Guide to the Human Genome
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Search of human proteins with 18104969

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
precursor [Homo sapiens]
         (562 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec...  1183   0.0  
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec...  1164   0.0  
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo...   727   0.0  
gi|109150416 peroxidasin [Homo sapiens]                                55   2e-07
gi|28558982 thyroid peroxidase isoform a [Homo sapiens]                50   5e-06
gi|28558984 thyroid peroxidase isoform b [Homo sapiens]                50   5e-06
gi|28558988 thyroid peroxidase isoform d [Homo sapiens]                50   5e-06
gi|132566532 dual oxidase 2 precursor [Homo sapiens]                   45   1e-04
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]        45   1e-04
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]        45   1e-04
gi|20149640 dual oxidase 1 precursor [Homo sapiens]                    44   3e-04
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                    44   3e-04
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]        44   3e-04
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]         44   3e-04
gi|4557679 jagged 1 precursor [Homo sapiens]                           43   7e-04
gi|41327708 crumbs homolog 1 precursor [Homo sapiens]                  42   0.001
gi|4557759 myeloperoxidase [Homo sapiens]                              42   0.001
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]    42   0.001
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]     42   0.001
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]              41   0.003
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   40   0.006
gi|134244285 Notch homolog 3 [Homo sapiens]                            40   0.007
gi|24041035 notch 2 preproprotein [Homo sapiens]                       40   0.007
gi|148833508 notch1 preproprotein [Homo sapiens]                       39   0.010
gi|110735443 delta-like 1 [Homo sapiens]                               39   0.013
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa...    39   0.017
gi|4759146 slit homolog 2 [Homo sapiens]                               38   0.022
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]                38   0.028
gi|11321571 slit homolog 3 [Homo sapiens]                              37   0.037
gi|122937283 6720455I24Rik homolog [Homo sapiens]                      37   0.037

>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
           precursor [Homo sapiens]
          Length = 562

 Score = 1183 bits (3060), Expect = 0.0
 Identities = 562/562 (100%), Positives = 562/562 (100%)

Query: 1   MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60
           MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
Sbjct: 1   MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60

Query: 61  TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120
           TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
Sbjct: 61  TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120

Query: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180
           NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
Sbjct: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180

Query: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240
           LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
Sbjct: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240

Query: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300
           YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
Sbjct: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300

Query: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360
           ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
Sbjct: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360

Query: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKIGGGRNMDHHILHVAVDVIRESREM 420
           DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKIGGGRNMDHHILHVAVDVIRESREM
Sbjct: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKIGGGRNMDHHILHVAVDVIRESREM 420

Query: 421 RLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIF 480
           RLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIF
Sbjct: 421 RLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIF 480

Query: 481 GESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYV 540
           GESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYV
Sbjct: 481 GESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYV 540

Query: 541 SFRVPDASQDDGPAVERPSTEL 562
           SFRVPDASQDDGPAVERPSTEL
Sbjct: 541 SFRVPDASQDDGPAVERPSTEL 562


>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
           precursor [Homo sapiens]
          Length = 599

 Score = 1164 bits (3012), Expect = 0.0
 Identities = 562/599 (93%), Positives = 562/599 (93%), Gaps = 37/599 (6%)

Query: 1   MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60
           MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
Sbjct: 1   MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60

Query: 61  TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120
           TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
Sbjct: 61  TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120

Query: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180
           NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
Sbjct: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180

Query: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240
           LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
Sbjct: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240

Query: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300
           YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
Sbjct: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300

Query: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360
           ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
Sbjct: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360

Query: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK------------------------- 395
           DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK                         
Sbjct: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA 420

Query: 396 ------------IGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL 443
                       IGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
Sbjct: 421 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL 480

Query: 444 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS 503
           VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
Sbjct: 481 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS 540

Query: 504 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 562
           PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
Sbjct: 541 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 599


>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
           sapiens]
          Length = 604

 Score =  727 bits (1876), Expect = 0.0
 Identities = 340/552 (61%), Positives = 415/552 (75%), Gaps = 38/552 (6%)

Query: 33  NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL 92
           NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NC+ P   T ++  L+P+P+  H++L
Sbjct: 19  NPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYIL 78

Query: 93  THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL 151
           TH + FW  VN   F+R  +M  VLT RS+LI SPPTYN+ + Y SWE+FSN+SYYTR L
Sbjct: 79  THFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRAL 138

Query: 152 PSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKT 211
           P VP DCPTP+G KGKKQLPD+  +  + LLRRKFIPDPQG+N+MFAFFAQHFTHQFFKT
Sbjct: 139 PPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKT 198

Query: 212 SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL 271
             K GP FT  LGHGVDL HIYG+ L RQ +LRLFKDGK+KYQ++DGEMYPP+V++    
Sbjct: 199 DHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAE 258

Query: 272 MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT 331
           M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT+
Sbjct: 259 MIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTS 318

Query: 332 RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP 391
           RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+P
Sbjct: 319 RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLP 378

Query: 392 DSF-------------------------------------KIGGGRNMDHHILHVAVDVI 414
           D+F                                     ++ GGRN+   +  V+   I
Sbjct: 379 DTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASI 438

Query: 415 RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC 474
            +SR+M+ Q FNEYRKRF +KPY SF+EL GEKEM+AELE LYGDIDA+E YP LL+EK 
Sbjct: 439 DQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKP 498

Query: 475 HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT 534
            P++IFGE+M+E+GAPFSLKGL+GN ICSP YWKPSTFGGEVGF I+ TA+++ L+C N 
Sbjct: 499 RPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNV 558

Query: 535 KTCPYVSFRVPD 546
           K CP+ SF VPD
Sbjct: 559 KGCPFTSFSVPD 570


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 71/332 (21%), Positives = 125/332 (37%), Gaps = 70/332 (21%)

Query: 296  GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF 355
            GL    TLW REHNR+   L   +P W  + ++  TR I+  E   I  + ++ ++ G  
Sbjct: 983  GLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEV 1042

Query: 356  LQLK------FDPELLFGVQFQYRNRIAMEFNH------LYHWH---------------- 387
                      +DP +  G+ F      A  F H      LY                   
Sbjct: 1043 GMRTLGEYHGYDPGINAGI-FNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKA 1101

Query: 388  --------------PLMPDSFKIGGGRNMDHHILH-------------VAVDV----IRE 416
                          PL+   F + G   +   +L+             VA+D+    I+ 
Sbjct: 1102 FFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQR 1161

Query: 417  SREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGLLLEK 473
             R+  + P+++YR    +    +F++L  E    E+  +L+ LYG    ++ +P L++E 
Sbjct: 1162 GRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVED 1221

Query: 474  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN 533
              P S  G +++ + +    +   G+ +    Y  P  F        +K  +L +++C N
Sbjct: 1222 LVPGSRLGPTLMCLLSTQFKRLRDGDRLW---YENPGVF-SPAQLTQIKQTSLARILCDN 1277

Query: 534  TKTCPYVS---FRVPDASQDDGPAVERPSTEL 562
                  V    FRV +     G   E P  +L
Sbjct: 1278 ADNITRVQSDVFRVAEFPHGYGSCDEIPRVDL 1309


>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
          Length = 933

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)

Query: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
           +D   +YG +  LERQ +     +G L+        G  Y P V   AP       GIP 
Sbjct: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383

Query: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
           +++      G      +P L    TLWLREHNR+   LKA +  W  + ++Q  R ++  
Sbjct: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443

Query: 338 ETIKIVIEEYVQQLSG 353
               I + +Y+ ++ G
Sbjct: 444 LHQIITLRDYIPRILG 459


>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
          Length = 876

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)

Query: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
           +D   +YG +  LERQ +     +G L+        G  Y P V   AP       GIP 
Sbjct: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383

Query: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
           +++      G      +P L    TLWLREHNR+   LKA +  W  + ++Q  R ++  
Sbjct: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443

Query: 338 ETIKIVIEEYVQQLSG 353
               I + +Y+ ++ G
Sbjct: 444 LHQIITLRDYIPRILG 459


>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
          Length = 889

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)

Query: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
           +D   +YG +  LERQ +     +G L+        G  Y P V   AP       GIP 
Sbjct: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383

Query: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
           +++      G      +P L    TLWLREHNR+   LKA +  W  + ++Q  R ++  
Sbjct: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443

Query: 338 ETIKIVIEEYVQQLSG 353
               I + +Y+ ++ G
Sbjct: 444 LHQIITLRDYIPRILG 459


>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
          Length = 1548

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 28/159 (17%)

Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR 276
           +D   IYG +      LR F  G+L       +   P   + P+LM          + PR
Sbjct: 179 LDGSAIYGSSHSWSDALRSFSGGQL---ASGPDPAFPRDSQNPLLMWAAPDPATGQNGPR 235

Query: 277 GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
           G+      A G E     P L     LW R HN     L  +HP W DE+LFQ  R  +I
Sbjct: 236 GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI 290

Query: 337 GETIKIVIEEY--------VQQLSGY--FLQLKFDPELL 365
                I + E+        + + +GY  FL     PE +
Sbjct: 291 ATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISPEFV 329


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 10/63 (15%)

Query: 19   LPVLLADP---------GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
            LP L+AD          G   P   C    C +QG+C++   D + CDCT T Y GP C 
Sbjct: 1075 LPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQ-QWDGFTCDCTMTSYGGPVCN 1133

Query: 70   IPG 72
             PG
Sbjct: 1134 DPG 1136



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 35  CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           C   PC++ G+C R G +R+ CDC  TG+ G  C
Sbjct: 694 CASAPCRNGGVC-REGWNRFICDCIGTGFLGRVC 726



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 4/54 (7%)

Query: 20  PVLLADPGAP-TPVNPCCY---YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
           P LL   G      +P C     PC + G+C         CDC+ TG+ G  C+
Sbjct: 189 PALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCS 242


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 10/63 (15%)

Query: 19   LPVLLADP---------GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
            LP L+AD          G   P   C    C +QG+C++   D + CDCT T Y GP C 
Sbjct: 1035 LPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQ-QWDGFTCDCTMTSYGGPVCN 1093

Query: 70   IPG 72
             PG
Sbjct: 1094 DPG 1096



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 35  CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           C   PC++ G+C R G +R+ CDC  TG+ G  C
Sbjct: 663 CASAPCRNGGVC-REGWNRFICDCIGTGFLGRVC 695



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 4/54 (7%)

Query: 20  PVLLADPGAP-TPVNPCCY---YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
           P LL   G      +P C     PC + G+C         CDC+ TG+ G  C+
Sbjct: 189 PALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCS 242


>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 18/132 (13%)

Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR 276
           +D   IYG +      LR F  G+L       +   P   + P+LM          + PR
Sbjct: 173 LDGSAIYGSSHSWSDALRSFSRGQL---ASGPDPAFPRDSQNPLLMWAAPDPATGQNGPR 229

Query: 277 GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
           G+      A G E     P L     LW R HN     L  +HP W DE+LFQ  R  +I
Sbjct: 230 GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI 284

Query: 337 GETIKIVIEEYV 348
                I + E++
Sbjct: 285 ATYQNIAVYEWL 296


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 18/132 (13%)

Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR 276
           +D   IYG +      LR F  G+L       +   P   + P+LM          + PR
Sbjct: 173 LDGSAIYGSSHSWSDALRSFSRGQL---ASGPDPAFPRDSQNPLLMWAAPDPATGQNGPR 229

Query: 277 GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
           G+      A G E     P L     LW R HN     L  +HP W DE+LFQ  R  +I
Sbjct: 230 GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI 284

Query: 337 GETIKIVIEEYV 348
                I + E++
Sbjct: 285 ATYQNIAVYEWL 296


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query: 34  PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct: 719 PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC 752



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 27   GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG 72
            G   P   C    C +QG+C++   D + CDC+ T +SGP C  PG
Sbjct: 1119 GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG 1163



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 5/31 (16%)

Query: 44  GICVRFGL-----DRYQCDCTRTGYSGPNCT 69
           G+C+  G+     D+  CDC+RTG+ G +C+
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS 256


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query: 34  PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct: 679 PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC 712



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 27   GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG 72
            G   P   C    C +QG+C++   D + CDC+ T +SGP C  PG
Sbjct: 1079 GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG 1123



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 5/31 (16%)

Query: 44  GICVRFGL-----DRYQCDCTRTGYSGPNCT 69
           G+C+  G+     D+  CDC+RTG+ G +C+
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS 256


>gi|4557679 jagged 1 precursor [Homo sapiens]
          Length = 1218

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 37  YYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           + PC + G C   G D+YQC C   GYSGPNC I
Sbjct: 303 HQPCLNGGTCSNTGPDKYQCSCPE-GYSGPNCEI 335



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 2/38 (5%)

Query: 33  NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           N C  +PC + G CV  G + Y+C+C   G++GP+C I
Sbjct: 784 NDCSPHPCYNSGTCVD-GDNWYRCECA-PGFAGPDCRI 819



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 2/39 (5%)

Query: 30  TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           T +N C   PC + G C R  ++ + CDC + G+ G  C
Sbjct: 666 TNINDCSQNPCHNGGTC-RDLVNDFYCDC-KNGWKGKTC 702



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           +N C   PC++ G C+  G++ Y+C C+  G+ G  C
Sbjct: 630 INDCESNPCRNGGTCID-GVNSYKCICS-DGWEGAYC 664


>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
          Length = 1406

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 3/43 (6%)

Query: 35  CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC--TIPGLWT 75
           C   PC H G+CV  G +RY C+CT +G++G +C   +P  W+
Sbjct: 266 CASQPCLHGGLCVD-GENRYSCNCTGSGFTGTHCETLMPLCWS 307



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 6/43 (13%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDC-----TRTGYSGPNCT 69
           VN C   PCQ+ G C       Y C C     +RT Y G +C+
Sbjct: 398 VNECSSNPCQNGGTCENLP-GNYTCHCPFDNLSRTFYGGRDCS 439


>gi|4557759 myeloperoxidase [Homo sapiens]
          Length = 745

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 294 LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV-IEEYVQQLS 352
           +P L    TL LREHNR+   LK+ +P W  E+L+Q  R I +G  ++I+   +Y+  + 
Sbjct: 409 MPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKI-VGAMVQIITYRDYLPLVL 467

Query: 353 GYFLQLKFDP 362
           G     K+ P
Sbjct: 468 GPTAMRKYLP 477


>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
          Length = 629

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/61 (39%), Positives = 32/61 (52%)

Query: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361
           TL+LREHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  L G  +Q    
Sbjct: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360

Query: 362 P 362
           P
Sbjct: 361 P 361


>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
          Length = 712

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/61 (39%), Positives = 32/61 (52%)

Query: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361
           TL+LREHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  L G  +Q    
Sbjct: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443

Query: 362 P 362
           P
Sbjct: 444 P 444


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 14/70 (20%)

Query: 27  GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG------------LW 74
           G   P   C    C +QG+C++   + + CDC+ T YSG  C  PG            L+
Sbjct: 672 GCEGPSTTCQEDSCANQGVCMQ-QWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILY 730

Query: 75  TWLRNSLRPS 84
           TW  N  RPS
Sbjct: 731 TWPAND-RPS 739



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 35  CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           C  YPC++  +C + G +R+ CDCT TGY G  C
Sbjct: 274 CDSYPCKNNAVC-KDGWNRFICDCTGTGYWGRTC 306


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 17/137 (12%)

Query: 227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLD-GEMYPPSVEEAPVLMHYPRGIPPQSQMA 285
            +D  ++YG + ER+ Q    +D  +   +L  G  +PPS +    L+ +  G PP     
Sbjct: 894  IDGSNVYGSS-ERESQA--LRDPSVPRGLLKTGFPWPPSGKP---LLPFSTG-PPTECAR 946

Query: 286  VGQEVFGLLPG---------LMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
              QE    L G         L    TLW REHNRV   L A +P W    ++Q  R I+ 
Sbjct: 947  QEQESPCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVG 1006

Query: 337  GETIKIVIEEYVQQLSG 353
             E   I    ++ ++ G
Sbjct: 1007 AELQHITYSHWLPKVLG 1023



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 18/79 (22%), Positives = 41/79 (51%), Gaps = 3/79 (3%)

Query: 410  AVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFY 466
            A  +I+  R+  + P+ ++R    +    +F++L  E    E+  +L +LYG    ++ +
Sbjct: 1138 AATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLW 1197

Query: 467  PGLLLEKCHPNSIFGESMI 485
            P L++E   P +  G +++
Sbjct: 1198 PALMVEDLIPGTRVGPTLM 1216


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            V+PC   PCQH G C R  +  Y C+C   GY+G NC
Sbjct: 1085 VDPCLAQPCQHGGTC-RGYMGGYMCECL-PGYNGDNC 1119



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 4/42 (9%)

Query: 33  NPCCYYPCQHQGIC---VRFGLDRYQCDCTRTGYSGPNCTIP 71
           +PC   PC  +G+C   V  G  R+ C C R G+ GP+C++P
Sbjct: 80  DPCHSGPCAGRGVCQSSVVAGTARFSCRCPR-GFRGPDCSLP 120



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 1/51 (1%)

Query: 20  PVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           P     P    P  PC   PC++ G C + G   Y C C   G+ G NC +
Sbjct: 186 PAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL-PGFEGQNCEV 235



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 10/60 (16%)

Query: 12  FLLLLPP--LPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
           F  L PP  LP L   P      +PC + PC H GIC       ++C C   G+SGP C+
Sbjct: 679 FRCLCPPGSLPPLCLPPS-----HPCAHEPCSH-GICYD-APGGFRCVC-EPGWSGPRCS 730



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           V+ C   PC+H G C+   +D+Y C C  +G +G NC +
Sbjct: 583 VDECRSQPCRHGGKCLDL-VDKYLCRCP-SGTTGVNCEV 619



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 4/46 (8%)

Query: 26  PGAPTPVNPCCYYPCQHQGICV-RFGLDRYQCDCTRTGYSGPNCTI 70
           P   T VN C   PC++Q  C+ R G  ++ C C   G++G  C +
Sbjct: 426 PRCETDVNECLSGPCRNQATCLDRIG--QFTCIC-MAGFTGTYCEV 468



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 2/39 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
            V+ C   PCQH G C+   + RY C C   G  G  C I
Sbjct: 1123 VDECASQPCQHGGSCIDL-VARYLCSCP-PGTLGVLCEI 1159



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           ++PC   PC+H G C         C C + G+ GP C
Sbjct: 772 LSPCTPNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRC 807


>gi|24041035 notch 2 preproprotein [Homo sapiens]
          Length = 2471

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            +N C  +PC ++G CV  GL  Y+C C   GY+G NC
Sbjct: 1026 INECSSHPCLNEGTCVD-GLGTYRCSCP-LGYTGKNC 1060



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            ++ C   PCQH   C  F +  Y+C+C   GY G NC
Sbjct: 1150 LDECASNPCQHGATCSDF-IGGYRCECV-PGYQGVNC 1184



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 2/30 (6%)

Query: 39  PCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           PC+H G CV      + C+C + GY+GP C
Sbjct: 426 PCEHAGKCVNTD-GAFHCECLK-GYAGPRC 453



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           +N C   PC + G CV   ++R+QC C   G++GP C I
Sbjct: 495 INECQSNPCVNNGQCVD-KVNRFQCLCP-PGFTGPVCQI 531



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%)

Query: 30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGL 73
            T VN C   PC+++G CV+   +  QC C  +G++G  C +P +
Sbjct: 1062 TLVNLCSRSPCKNKGTCVQKKAES-QCLCP-SGWAGAYCDVPNV 1103



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 33  NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           N C   PCQ+ G C    ++ Y+C C + G+ G NC +
Sbjct: 759 NECLSNPCQNGGTCDNL-VNGYRCTC-KKGFKGYNCQV 794



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)

Query: 40   CQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            CQH G+C+  G   Y C C   GY+G  C
Sbjct: 1120 CQHSGVCINAGNTHY-CQCP-LGYTGSYC 1146



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 30  TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           T +N C   PC++ G C  + ++ Y C C + G+ G +C
Sbjct: 948 TDMNECLSEPCKNGGTCSDY-VNSYTCKC-QAGFDGVHC 984



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 11/30 (36%), Positives = 16/30 (53%), Gaps = 1/30 (3%)

Query: 39  PCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           PC + G C     D Y+C C + G++G  C
Sbjct: 114 PCLNGGTCHMLSRDTYECTC-QVGFTGKEC 142



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 12/35 (34%), Positives = 18/35 (51%), Gaps = 1/35 (2%)

Query: 34  PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           PC   PC + G C + G   ++C+C   G+ G  C
Sbjct: 224 PCAPSPCVNGGTCRQTGDFTFECNCL-PGFEGSTC 257



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 2/42 (4%)

Query: 30  TPVNPCCYYPCQHQGICVRF-GLDRYQCDCTRTGYSGPNCTI 70
           T + PC   PC++  +C      + Y C C   G+ G  CTI
Sbjct: 832 TVLAPCSPNPCENAAVCKESPNFESYTCLCA-PGWQGQRCTI 872


>gi|148833508 notch1 preproprotein [Homo sapiens]
          Length = 2555

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            VN C   PC H G C + G   Y+C C + GY+GPNC
Sbjct: 1022 VNECDSQPCLHGGTC-QDGCGSYRCTCPQ-GYTGPNC 1056



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 3/46 (6%)

Query: 25  DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           DP   + VN C   PC H G C R  L+ Y+CDC   G+SG NC I
Sbjct: 710 DPTCLSEVNECNSNPCVH-GAC-RDSLNGYKCDCD-PGWSGTNCDI 752



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 4/42 (9%)

Query: 33  NPCCYYPCQHQGIC---VRFGLDRYQCDCTRTGYSGPNCTIP 71
           NPC   PC++ G C    R G+  Y C C   G+SGP C  P
Sbjct: 61  NPCLSTPCKNAGTCHVVDRRGVADYACSCA-LGFSGPLCLTP 101



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 26  PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           P    P  PC   PCQ+ G C   G   ++C C   G++G NC
Sbjct: 213 PNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL-PGFTGQNC 254



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 30  TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           T +N C   PC+H G C +   + Y C C + G +GPNC I
Sbjct: 602 TNINECSSQPCRHGGTC-QDRDNAYLCFCLK-GTTGPNCEI 640



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 26  PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           P   T +N C   PC +QG C+   +  Y+C+C    Y+G  C +
Sbjct: 786 PNCQTNINECASNPCLNQGTCID-DVAGYKCNCL-LPYTGATCEV 828



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 2/40 (5%)

Query: 30  TPV-NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           TP+ N C   PC++ G C    L  Y+C C   G+SG +C
Sbjct: 100 TPLDNACLTNPCRNGGTCDLLTLTEYKCRCP-PGWSGKSC 138



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           +N C   PC+H   C       Y+C C + GYSG NC
Sbjct: 870 INECVLSPCRHGASCQNTH-GGYRCHC-QAGYSGRNC 904



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 2/45 (4%)

Query: 26  PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           P     VN C   PCQ+   C+   +  +QC C   GY G +C +
Sbjct: 447 PRCEIDVNECVSNPCQNDATCLD-QIGEFQCIC-MPGYEGVHCEV 489



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 16/36 (44%), Positives = 18/36 (50%), Gaps = 2/36 (5%)

Query: 33  NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           N C   PC + G C       Y C C R G+SGPNC
Sbjct: 755 NECESNPCVNGGTCKDM-TSGYVCTC-REGFSGPNC 788



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
            ++ C  +PCQ+ G C+    + Y+C C R G  G +C I
Sbjct: 1184 IDECLSHPCQNGGTCLDLP-NTYKCSCPR-GTQGVHCEI 1220


>gi|110735443 delta-like 1 [Homo sapiens]
          Length = 723

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 2/38 (5%)

Query: 31  PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           PV+ C + PC +   C   G  RY C+C R GY GPNC
Sbjct: 481 PVSRCEHAPCHNGATCHERG-HRYVCECAR-GYGGPNC 516



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 32  VNPCCYY-PCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           +N C ++ PC++   C   G   Y C C R GY+G  C +
Sbjct: 289 LNYCTHHKPCKNGATCTNTGQGSYTCSC-RPGYTGATCEL 327


>gi|38348304 von Willebrand factor A domain containing 2 [Homo
           sapiens]
          Length = 725

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 17/37 (45%), Positives = 19/37 (51%)

Query: 34  PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           PC   PCQ+ G CV  GLD YQC C        NC +
Sbjct: 298 PCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCAL 334


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)

Query: 33  NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP 71
           NPC   PC++ G C    +D Y+C C   G+ G +C +P
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDFYRCTCP-YGFKGQDCDVP 957



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 31  PVNPCCYYPCQHQGIC-VRFG-LDRYQCDCTRTGYSGPNCTI 70
           P++ C   PC+H G C ++ G  D + C C   G+ G NC +
Sbjct: 957 PIHACISNPCKHGGTCHLKEGEEDGFWCICA-DGFEGENCEV 997


>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
          Length = 3144

 Score = 37.7 bits (86), Expect = 0.028
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 2/37 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            ++ C   PC H G+C+  G++ Y CDC ++G+ G +C
Sbjct: 1005 LDECLSEPCLHDGVCID-GINHYTCDC-KSGFFGTHC 1039



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
            +PC    C + G C+  G   Y C+CT TG+ G  CT
Sbjct: 2612 SPCSLMKCGNGGTCIESGTSVY-CNCT-TGWKGSFCT 2646



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 2/39 (5%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
           +N C   PC++ G CV    +R+ C+C    Y GP C +
Sbjct: 929 INECSSEPCKNNGTCVDL-TNRFFCNC-EPEYHGPFCEL 965



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
            +N C   PC ++G C +     + C C R GY+G  C
Sbjct: 1080 INDCTSIPCMNEGFCQK-SAHGFTCICPR-GYTGAYC 1114


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 33  NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP 71
           N C   PC++ G C +  ++ Y+C C  + Y G +CT+P
Sbjct: 918 NACLSSPCKNNGTCTQDPVELYRCACPYS-YKGKDCTVP 955



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 16/42 (38%), Positives = 19/42 (45%), Gaps = 3/42 (7%)

Query: 31  PVNPCCYYPCQHQGIC--VRFGLDRYQCDCTRTGYSGPNCTI 70
           P+N C   PCQH G C       D + C C   G+ G  C I
Sbjct: 955 PINTCIQNPCQHGGTCHLSDSHKDGFSCSCP-LGFEGQRCEI 995


>gi|122937283 6720455I24Rik homolog [Homo sapiens]
          Length = 1413

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%)

Query: 32  VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
           VN C   PCQ+ G C   G++ ++C C   G+ GP C
Sbjct: 312 VNECASQPCQNGGTCTH-GINSFRCQCP-AGFGGPTC 346



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)

Query: 35   CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
            C   PCQ+ G CV  G D + CDC   G+ G  C +
Sbjct: 1311 CSENPCQNGGTCVP-GADAHSCDC-GPGFKGRRCEL 1344


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.142    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,472,806
Number of Sequences: 37866
Number of extensions: 1204011
Number of successful extensions: 2922
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 2738
Number of HSP's gapped (non-prelim): 236
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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