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Search of human proteins with 18079262
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18079262 tripartite motif-containing 6 isoform 2 [Homo
sapiens]
(488 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 1011 0.0
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 1011 0.0
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 612 e-175
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 563 e-160
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 563 e-160
gi|117938316 tripartite motif-containing 22 [Homo sapiens] 547 e-156
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 531 e-151
gi|15208660 tripartite motif protein 21 [Homo sapiens] 400 e-111
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 383 e-106
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 383 e-106
gi|37622899 ring finger protein 137 [Homo sapiens] 342 3e-94
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 328 9e-90
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 310 2e-84
gi|5454014 tripartite motif-containing 38 [Homo sapiens] 295 5e-80
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 287 2e-77
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 270 2e-72
gi|5730009 ret finger protein [Homo sapiens] 268 1e-71
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 260 2e-69
gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens] 253 2e-67
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 234 1e-61
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 234 1e-61
gi|22749269 ring finger protein 129 [Homo sapiens] 226 4e-59
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 221 1e-57
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 218 1e-56
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 214 1e-55
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] 213 3e-55
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 206 4e-53
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 201 2e-51
gi|4557743 Mediterranean fever protein [Homo sapiens] 199 6e-51
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 198 8e-51
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
Length = 488
Score = 1011 bits (2614), Expect = 0.0
Identities = 488/488 (100%), Positives = 488/488 (100%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ
Sbjct: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE
Sbjct: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360
VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD
Sbjct: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360
Query: 361 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 420
VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP
Sbjct: 361 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 420
Query: 421 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP 480
SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP
Sbjct: 421 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP 480
Query: 481 MTLRRPSS 488
MTLRRPSS
Sbjct: 481 MTLRRPSS 488
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 1011 bits (2614), Expect = 0.0
Identities = 488/488 (100%), Positives = 488/488 (100%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ
Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE
Sbjct: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360
VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD
Sbjct: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 388
Query: 361 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 420
VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP
Sbjct: 389 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 448
Query: 421 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP 480
SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP
Sbjct: 449 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP 508
Query: 481 MTLRRPSS 488
MTLRRPSS
Sbjct: 509 MTLRRPSS 516
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 612 bits (1579), Expect = e-175
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ
Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE
Sbjct: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
Score = 563 bits (1451), Expect = e-160
Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC
Sbjct: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE
Sbjct: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R
Sbjct: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW
Sbjct: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360
VDVTLN NLNLVL++++RQV +S P + Y+ VLGSQ+FSSGKHYWEVD
Sbjct: 655 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 708
Query: 361 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 418
V+KKTAWILGV + + A + Y++Y+P GYWVIGLQ+ +Y +E+S
Sbjct: 709 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 768
Query: 419 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474
S L LSM VPP RVGVFLDYEAG VSF+NVT+HG IY FSK F + PYFNP
Sbjct: 769 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 828
Query: 475 CNCVIPMTLRRPSS 488
NC PMTL PSS
Sbjct: 829 WNCPAPMTLCPPSS 842
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 563 bits (1451), Expect = e-160
Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC
Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE
Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360
VDVTLN NLNLVL++++RQV +S P + Y+ VLGSQ+FSSGKHYWEVD
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 354
Query: 361 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 418
V+KKTAWILGV + + A + Y++Y+P GYWVIGLQ+ +Y +E+S
Sbjct: 355 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 414
Query: 419 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474
S L LSM VPP RVGVFLDYEAG VSF+NVT+HG IY FSK F + PYFNP
Sbjct: 415 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 474
Query: 475 CNCVIPMTLRRPSS 488
NC PMTL PSS
Sbjct: 475 WNCPAPMTLCPPSS 488
>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 563 bits (1451), Expect = e-160
Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC
Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE
Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360
VDVTLN NLNLVL++++RQV +S P + Y+ VLGSQ+FSSGKHYWEVD
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 354
Query: 361 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 418
V+KKTAWILGV + + A + Y++Y+P GYWVIGLQ+ +Y +E+S
Sbjct: 355 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 414
Query: 419 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474
S L LSM VPP RVGVFLDYEAG VSF+NVT+HG IY FSK F + PYFNP
Sbjct: 415 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 474
Query: 475 CNCVIPMTLRRPSS 488
NC PMTL PSS
Sbjct: 475 WNCPAPMTLCPPSS 488
>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
Length = 498
Score = 547 bits (1409), Expect = e-156
Identities = 287/501 (57%), Positives = 355/501 (70%), Gaps = 16/501 (3%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT +ESVI GE SCPVCQ
Sbjct: 1 MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
T +QPGNLRPNRHLANIV R++EV + P + K +C HG+KLQ+FC+EDGKVICW+CE
Sbjct: 61 TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
SQEH+GH TF + EV +E QEK Q +L++L E+QEAEKL IR+++T+WKN ++ ER
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
+I FN++R ILD EQREL+KLE+ E L + A + LV Q Q LISDL+RR
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
+GS++E+LQDV DV +RSE WTL+KP+++ KL+S+FR PDL ML+V +ELTDVQ YW
Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGA---KVSGPSCLEKHYDCSVLGSQHFSSGKHYW 357
VDV LNP +A N+ ++ ++RQV+ V K S P V G Q+FSSGK+YW
Sbjct: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAF---GVFGCQYFSSGKYYW 357
Query: 358 EVDVAKKTAWILGVCS--NSLGPT----FSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 411
EVDV+ K AWILGV S +SL F+F+ YSRY+PQ GYWVIGLQ+ E
Sbjct: 358 EVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCE 417
Query: 412 YRAYEDSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTT 467
Y A+EDSS S L L M VPP R+GVFLDYEAG VSF+NVTNHG IY FS F
Sbjct: 418 YNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRP 477
Query: 468 LCPYFNPCNCVIPMTLRRPSS 488
PYFNP NC++PMT+ PSS
Sbjct: 478 AYPYFNPWNCLVPMTVCPPSS 498
>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
Length = 493
Score = 531 bits (1367), Expect = e-151
Identities = 281/502 (55%), Positives = 353/502 (70%), Gaps = 23/502 (4%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+
Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SYQP N+RPNRH+AN+V +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60 ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHTF EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
+ +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
Query: 301 VDVTLNPHTANLNLVLAKNRRQVR------FVGAK-VSGPSCLEKHYDCSVLGSQHFSSG 353
VDVT+ P+ + V+++++RQV GA+ + + +Y +LGSQ +SG
Sbjct: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
Query: 354 KHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYR 413
KHYWEVDV+KKTAWILGVC+ N YQP+ GYWVIGL+ +
Sbjct: 358 KHYWEVDVSKKTAWILGVCAGFQPDAMC------NIEKNENYQPKYGYWVIGLEEGVKCS 411
Query: 414 AYEDSS---PS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPT 466
A++DSS PS + LS+ + P RVGVFLDYEA TVSF+N+TNHGF IY FS F
Sbjct: 412 AFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQ 471
Query: 467 TLCPYFNPCNCVIPMTLRRPSS 488
+ PY NP C +PMTL PSS
Sbjct: 472 PVFPYLNPRKCGVPMTLCSPSS 493
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 400 bits (1029), Expect = e-111
Identities = 215/466 (46%), Positives = 294/466 (63%), Gaps = 31/466 (6%)
Query: 11 EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 70
EEVTCPICL+ EP+SI+CGHSFCQ CI S +G+ G CPVC+ + NLRP
Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65
Query: 71 NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 130
NR LAN+V L+E+ + + CA HGE+L LFC++DGK +CW+C +S++HR H
Sbjct: 66 NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125
Query: 131 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 190
+EE AQEYQEK Q +L +L+ +++ AEKL I K+ WK +E ++ RI EF Q
Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185
Query: 191 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 250
+N L EQR+L++LE++E++ LRI+ E E L Q+Q+L+ELIS+L+RRC S +ELLQ
Sbjct: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245
Query: 251 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTA 310
+V V ERSE W L+ + +LRS+ P LK+MLR C V +TL+P TA
Sbjct: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCA---------VHITLDPDTA 296
Query: 311 NLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC--SVLGSQHFSSGKHYWEVDVAKKTAWI 368
N L+L+++RRQVR + S P E+ +D VLG+QHF SGKHYWEVDV K AW
Sbjct: 297 NPWLILSEDRRQVRLGDTQQSIPG-NEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWD 355
Query: 369 LGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTV 428
LGVC +S+ + +SG+W I L + +Y A + P L + V
Sbjct: 356 LGVCRDSV-----------RRKGHFLLSSKSGFWTIWLWNKQKYEA--GTYPQTPLHLQV 402
Query: 429 PPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474
PP +VG+FLDYEAG VSFYN+T+HG IY+FS+ F L P+F+P
Sbjct: 403 PPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSP 448
>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
sapiens]
Length = 326
Score = 383 bits (984), Expect = e-106
Identities = 190/300 (63%), Positives = 233/300 (77%), Gaps = 2/300 (0%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+
Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SYQP N+RPNRH+ANIV +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60 ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
+ +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
sapiens]
Length = 347
Score = 383 bits (984), Expect = e-106
Identities = 190/300 (63%), Positives = 233/300 (77%), Gaps = 2/300 (0%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+
Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SYQP N+RPNRH+ANIV +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60 ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
+ +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
Query: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 342 bits (878), Expect = 3e-94
Identities = 185/478 (38%), Positives = 281/478 (58%), Gaps = 33/478 (6%)
Query: 9 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 68
I EEV CPIC+ L EP+SIDCGHSFC +C++ Q +CP+C+ QP NL
Sbjct: 10 IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69
Query: 69 RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 128
RPN LAN+V ++R + L PG LK LC HGEKL++FC+ED ++C C +S EH H
Sbjct: 70 RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129
Query: 129 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 188
+E+VA EY+ + E+L+ LK E++EA KL R++ +WK Q+E + I EF
Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189
Query: 189 QLRNILDRVE----------QRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 238
+ + +L++ + L L++E + ++ +E ++L+ Q+Q L +I++L+
Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249
Query: 239 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 298
R Q +LQD+ +V RS+ W+L++PE + +L++ R L+ +L+ +
Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILK---------T 300
Query: 299 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS-VLGSQHFSSGKHYW 357
Y DV L+P TA L+++++R++V + P E+ Y + VLGSQ SSG+HYW
Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360
Query: 358 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 417
EV+V ++ W LGVC ++ + P G+WVI L+ +EYRA D
Sbjct: 361 EVEVGDRSEWGLGVCKQNV-----------DRKEVVYLSPHYGFWVIRLRKGNEYRAGTD 409
Query: 418 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPC 475
P +LS+ VPPRRVG+F+DYEA +SFYNVT+ G I+TF +Y FP L PYF+PC
Sbjct: 410 EYP--ILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPC 465
>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
Length = 270
Score = 328 bits (840), Expect = 9e-90
Identities = 165/255 (64%), Positives = 199/255 (78%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC
Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60
Query: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE
Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120
Query: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180
Query: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240
Query: 241 CQGSTMELLQDVSDV 255
Q STMELLQD+S +
Sbjct: 241 SQWSTMELLQDMSGI 255
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 310 bits (793), Expect = 2e-84
Identities = 180/479 (37%), Positives = 272/479 (56%), Gaps = 32/479 (6%)
Query: 9 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 68
+RE+ CP+CL+ L EP+S+DCGHSFC CI+ +S Q G +CP C+ ++P
Sbjct: 10 LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69
Query: 69 RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 128
RPNR LA +V +R + LG G + CA HGE L FC+ED +CW+C+ EHR H
Sbjct: 70 RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127
Query: 129 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 188
T ++E A YQ K Q +L+ ++ E ++A A + +K WK ++E +R R + EF
Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187
Query: 189 QLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMEL 248
+ R L + EQR+L++LE EE+ L+ + E+++ LV Q+++L+EL +L+ RCQ + L
Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247
Query: 249 LQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPH 308
L+ V V RS+ T + E +P +L++ P + +LR + VDV L+P
Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLR---------KFQVDVKLDPA 298
Query: 309 TANLNLVLAKNRRQVRFVGAKVSGPSCLEKH--YDCSVLGSQHFSSGKHYWEVDVAKKTA 366
TA+ +L+L + R V+ P+ E+ + C +LG Q FSSG+HYWEV V +
Sbjct: 299 TAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPC-ILGLQSFSSGRHYWEVLVGEGAE 357
Query: 367 WILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSM 426
W LGVC ++L + P++G W + L +EY +SPS+ L
Sbjct: 358 WGLGVCQDTL-----------PRKGETTPSPENGVWALWLLKGNEYMVL--ASPSVPLLQ 404
Query: 427 TVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNC---VIPMT 482
PR +G+FLDYEAG +SFYNVT+ G IYTF++ F L PYF C+ ++P T
Sbjct: 405 LESPRCIGIFLDYEAGEISFYNVTD-GSYIYTFNQ-LFSGLLRPYFFICDATPLILPPT 461
>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
Length = 465
Score = 295 bits (756), Expect = 5e-80
Identities = 177/471 (37%), Positives = 263/471 (55%), Gaps = 41/471 (8%)
Query: 11 EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 67
EE TC ICL L+T P+SI+CGHS+C CIT N + + QE CP C+ + +
Sbjct: 12 EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70
Query: 68 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 127
LRPN+ L +++ L+E + + C +HGE+ LFC+++G++ICW CER+ +H+G
Sbjct: 71 LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123
Query: 128 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 187
H T LVE+V Q Y+EK Q+++ KLK E + + T WK +++ +R +I+++F
Sbjct: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183
Query: 188 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 247
L+ L E+ L +LE+EE++ L + + E L ++ L+ I +LE +CQGS +
Sbjct: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243
Query: 248 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLRVCRELTDVQSYWVDV 303
LLQ+V+D RS L EA+ +L +M D+K+MLR S+ V V
Sbjct: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR---------SHQVSV 294
Query: 304 TLNPHTANLNLVLAKNRRQVR--FVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDV 361
TL+P TA+ L+L+++RRQV + S + C VLG + F+SG+ Y+EVDV
Sbjct: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC-VLGCEGFTSGRRYFEVDV 353
Query: 362 AKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPS 421
+ T W LGVC ++ + +PQSG+W + L Y A +SP
Sbjct: 354 GEGTGWDLGVCMENV-----------QRGTGMKQEPQSGFWTLRLCKKKGYVAL--TSPP 400
Query: 422 LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472
L + P VG+FLDYEAG VSFYN N G I+TF K F TL PYF
Sbjct: 401 TSLHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 287 bits (734), Expect = 2e-77
Identities = 177/490 (36%), Positives = 266/490 (54%), Gaps = 37/490 (7%)
Query: 1 MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 59
M +P L +++EE TC ICL+ T+P+ DCGH+FC+ CI R EG +CP C
Sbjct: 1 MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56
Query: 60 QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 119
+ NLRPNR LA + R L P + +C H E L FC ++ +++C C
Sbjct: 57 RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114
Query: 120 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 179
ERS EH H +++ A++ + K ++SL+ L+ + Q+A A E W+ +E +
Sbjct: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174
Query: 180 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 239
R + EF +LR +L EQ+ L++LE+EE + L + E L Q+ L ELI++LE
Sbjct: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234
Query: 240 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSY 299
RCQ + LLQD+ D R + L+ PE +P +LR++ R P L LR R
Sbjct: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG------- 287
Query: 300 WVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS--VLGSQHFSSGKHYW 357
DVTL+P TAN L+L+++RR V+ + + P E+ +D VLG + F+SG+HYW
Sbjct: 288 --DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPER-FDPGPCVLGQERFTSGRHYW 344
Query: 358 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 417
EV+V +T+W LGVC ++ N +G+W++ +Y +
Sbjct: 345 EVEVGDRTSWALGVCRENV-----------NRKEKGELSAGNGFWILVF-----LGSYYN 388
Query: 418 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP-CN 476
SS L + PPRRVG+FLDYEAG +SFY+ T+ G ++ F + F TL P F+P +
Sbjct: 389 SSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFSPLSS 447
Query: 477 CVIPMTLRRP 486
PMT+ RP
Sbjct: 448 SPTPMTICRP 457
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 270 bits (690), Expect = 2e-72
Identities = 170/494 (34%), Positives = 266/494 (53%), Gaps = 32/494 (6%)
Query: 2 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQT 61
T+ L +++ E +C +CLE L EP+ I+CGH+FC+ACIT + E + CPVC+
Sbjct: 16 TAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----ERDFPCPVCRK 71
Query: 62 SYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER 121
+ + +LRPNR L ++V +++ K LC H E L LFC ED + +C +C
Sbjct: 72 TSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAI 131
Query: 122 SQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERC 181
S HR H +++ QEY+EK Q+ L+ L+ + QE + + +K K +E R
Sbjct: 132 SHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQ 191
Query: 182 RIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRC 241
+I EF +L LD +Q L +LE+EE+ L+ + E L + + L L +++E +C
Sbjct: 192 QILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKC 251
Query: 242 QGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWV 301
S E+L+DV E+ E + ++ +L F + R R++ ++
Sbjct: 252 LQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNF--SNFPRQYFALRKI--LKQLIA 307
Query: 302 DVTLNPHTANLNLVLAKNRRQVRFVGAKVSG-PSCLEK--HYDCSVLGSQHFSSGKHYWE 358
DVTL+P TA+ NLVL+++R+ V+FV ++ P + Y C VL ++ F+SG+HYWE
Sbjct: 308 DVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPC-VLATEGFTSGRHYWE 366
Query: 359 VDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 418
V+V KT W +GVC +S+ P++GYW + L + +Y A +
Sbjct: 367 VEVGDKTHWAVGVCRDSVSRKGELTPL-----------PETGYWRVRLWNGDKYAA--TT 413
Query: 419 SPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP---- 474
+P L + V P+RVG+FLDYEAGT+SFYNVT+ IYTF+ F L P F P
Sbjct: 414 TPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSH-IYTFTD-TFTEKLWPLFYPGIRA 471
Query: 475 -CNCVIPMTLRRPS 487
P+T+R P+
Sbjct: 472 GRKNAAPLTIRPPT 485
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 268 bits (684), Expect = 1e-71
Identities = 173/487 (35%), Positives = 256/487 (52%), Gaps = 43/487 (8%)
Query: 9 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 68
+++E TCP+CL+ EP+ +DCGH+ C AC+ + E SCP C+ ++ ++
Sbjct: 10 LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65
Query: 69 RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 124
RPNRHLAN+ V++LR E GPG ++ +C H E L+L+C+ED IC +C+RS+E
Sbjct: 66 RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123
Query: 125 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 184
HRGH +EE + ++E+ Q L LK + ++ A + + + + ER +I
Sbjct: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183
Query: 185 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 244
EF QL + L E R L +LE+ + I A L LI+ LE + Q
Sbjct: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243
Query: 245 TMELLQDVSDVTERSEFWTLRKPEALPTKL---------RSMFRAPDLKRM-------LR 288
T ELLQD+ D R+E + +P P L + +F LK+ +
Sbjct: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDME 303
Query: 289 VCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH--YDCSVLG 346
+EL + Q Y VDVTL+P TA +L+L+ N RQVR+ + P E+ + C VLG
Sbjct: 304 KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC-VLG 362
Query: 347 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGL 406
S F +G+HYWEV+V K W +GVC +S+ + S PQ+G+W + L
Sbjct: 363 SPCFIAGRHYWEVEVGDKAKWTIGVCEDSV---------CRKGGVTS--APQNGFWAVSL 411
Query: 407 QHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPT 466
+ EY A +SP L + P +RVG+FLDY+AG VSFYNVT +TFS F
Sbjct: 412 WYGKEYWAL--TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTFSHATFCG 468
Query: 467 TLCPYFN 473
+ PYF+
Sbjct: 469 PVRPYFS 475
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 260 bits (665), Expect = 2e-69
Identities = 175/525 (33%), Positives = 272/525 (51%), Gaps = 64/525 (12%)
Query: 2 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQT 61
T+ L +++ E +C +CLE L EP+ I+CGH+FC+ACIT + E + CPVC+
Sbjct: 16 TAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----ERDFPCPVCRK 71
Query: 62 SYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER 121
+ + +LRPNR L ++V +++ K LC H E L LFC ED + +C +C
Sbjct: 72 TSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAI 131
Query: 122 SQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERC 181
S HR H +++ QEY+EK Q+ L+ L+ + QE + + +K K +E R
Sbjct: 132 SHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQ 191
Query: 182 RIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRC 241
+I EF +L LD +Q L +LE+EE+ L+ + E L + + L L +++E +C
Sbjct: 192 QILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKC 251
Query: 242 QGSTMELLQDVSDVTERS-------EFWTL--RKPEALPTKLRSMFRAPDLKRMLRVCRE 292
S E+L+DV E++ T+ R +AL ++ + R +K M E
Sbjct: 252 LQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTM-----E 306
Query: 293 LTDV------------QSYWV----------DVTLNPHTANLNLVLAKNRRQVRFVGAKV 330
+T V + Y+ DVTL+P TA+ NLVL+++R+ V+FV ++
Sbjct: 307 VTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRL 366
Query: 331 SGPSCLEKH---YDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQ 387
+ Y C VL ++ F+SG+HYWEV+V KT W +GVC +S+
Sbjct: 367 RDLPDTPRRFTFYPC-VLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPL-- 423
Query: 388 NHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFY 447
P++GYW + L + +Y A ++P L + V P+RVG+FLDYEAGT+SFY
Sbjct: 424 ---------PETGYWRVRLWNGDKYAA--TTTPFTPLHIKVKPKRVGIFLDYEAGTLSFY 472
Query: 448 NVTNHGFPIYTFSKYYFPTTLCPYFNP-----CNCVIPMTLRRPS 487
NVT+ IYTF+ F L P F P P+T+R P+
Sbjct: 473 NVTDRSH-IYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPT 515
>gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]
Length = 243
Score = 253 bits (647), Expect = 2e-67
Identities = 136/249 (54%), Positives = 170/249 (68%), Gaps = 12/249 (4%)
Query: 246 MELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTL 305
MELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YWVDVTL
Sbjct: 1 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 60
Query: 306 NPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKT 365
N NLNLVL++++RQV +S P + Y+ VLGSQ+FSSGKHYWEVDV+KKT
Sbjct: 61 NSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKT 114
Query: 366 AWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPS-- 421
AWILGV + + A + Y++Y+P GYWVIGLQ+ +Y +E+S S
Sbjct: 115 AWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDP 174
Query: 422 --LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVI 479
L LSM VPP RVGVFLDYEAG VSF+NVT+HG IY FSK F + PYFNP NC
Sbjct: 175 EVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPA 234
Query: 480 PMTLRRPSS 488
PMTL PSS
Sbjct: 235 PMTLCPPSS 243
>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 234 bits (598), Expect = 1e-61
Identities = 161/480 (33%), Positives = 245/480 (51%), Gaps = 49/480 (10%)
Query: 9 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 62
++EE TC ICL+ T+P+ CGH+FC+ACI + E G++G R CP C+
Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68
Query: 63 YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 122
NL PNR L + ++ PG Q K LC +H E L+LFCQ+D IC +C S
Sbjct: 69 SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124
Query: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182
+EHR H EE Q Y+ K +E ++ L+ + L A + W+ +++ R R
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184
Query: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 242
I EF ++ L EQR L+ LE EE++ + E+ L Q SL L+ LE R
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244
Query: 243 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWV 301
+++LQD+ + R +++ PE A PT+ R++ R P +LR +
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLR---------GFLE 295
Query: 302 DVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH----YDCSVLGSQHFSSGKHYW 357
DV + +A L+L ++ RQ R++G+ G K Y C+V G FSSG+HYW
Sbjct: 296 DVVPDATSAYPYLLLYES-RQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSSGRHYW 353
Query: 358 EV--DVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ--PQSGYWVIGLQHNHEY- 412
EV ++ W LGVC + N S R P++G+WV+ L +Y
Sbjct: 354 EVGMNITGDALWALGVCRD-------------NVSRKDRVPKCPENGFWVVQLSKGTKYL 400
Query: 413 RAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472
+ +P +L+ PP +G+FLD+EAG VSFY+V++ G ++T+S+ FP L P+F
Sbjct: 401 STFSALTPVMLME---PPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPFF 456
>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 234 bits (598), Expect = 1e-61
Identities = 161/480 (33%), Positives = 245/480 (51%), Gaps = 49/480 (10%)
Query: 9 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 62
++EE TC ICL+ T+P+ CGH+FC+ACI + E G++G R CP C+
Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68
Query: 63 YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 122
NL PNR L + ++ PG Q K LC +H E L+LFCQ+D IC +C S
Sbjct: 69 SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124
Query: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182
+EHR H EE Q Y+ K +E ++ L+ + L A + W+ +++ R R
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184
Query: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 242
I EF ++ L EQR L+ LE EE++ + E+ L Q SL L+ LE R
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244
Query: 243 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWV 301
+++LQD+ + R +++ PE A PT+ R++ R P +LR +
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLR---------GFLE 295
Query: 302 DVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH----YDCSVLGSQHFSSGKHYW 357
DV + +A L+L ++ RQ R++G+ G K Y C+V G FSSG+HYW
Sbjct: 296 DVVPDATSAYPYLLLYES-RQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSSGRHYW 353
Query: 358 EV--DVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ--PQSGYWVIGLQHNHEY- 412
EV ++ W LGVC + N S R P++G+WV+ L +Y
Sbjct: 354 EVGMNITGDALWALGVCRD-------------NVSRKDRVPKCPENGFWVVQLSKGTKYL 400
Query: 413 RAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472
+ +P +L+ PP +G+FLD+EAG VSFY+V++ G ++T+S+ FP L P+F
Sbjct: 401 STFSALTPVMLME---PPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPFF 456
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 226 bits (576), Expect = 4e-59
Identities = 143/473 (30%), Positives = 247/473 (52%), Gaps = 33/473 (6%)
Query: 6 LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 65
LV+++EE +CPICLE L +P++I+CGH+FC++C++ + ++ + CPVC+ +
Sbjct: 7 LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDL----DDTFPCPVCRFCFPY 62
Query: 66 GNLRPNRHLANIVRRLREVVLGPGK---QLKAVLCADHGEKLQLFCQEDGKVICWLCERS 122
+ R N L N+ +++ + K Q + +C H + L LFC +D +++C C S
Sbjct: 63 KSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFS 122
Query: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182
+H+ H+ +++ A ++E + SL+ L+N + EK+ K K ++E +R
Sbjct: 123 TKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREE 182
Query: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 242
I +EF Q+R L ++ L++++ EE L + E +L +L+ L+ ++E +
Sbjct: 183 INSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSV 242
Query: 243 GSTMELLQDVSDVTERSEFWTLRKPEALPTKLR--SMFRAPDLKRMLRVCRELTDVQSYW 300
S +ELL + ++ L+ PE +L P + R+ ++ +
Sbjct: 243 QSNLELLTQAKSM--HHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRI------IKPFQ 294
Query: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC-SVLGSQHFSSGKHYWEV 359
VDV L+ +TA+ L+++++R+ VR+ K + + Y C +VLGSQ FSSG+HYWEV
Sbjct: 295 VDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEV 354
Query: 360 DVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSS 419
+V K WILGVC + L ++ S G+W IG Y A +
Sbjct: 355 EVGNKPKWILGVCQDCL-----LRNWQDQPSVL------GGFWAIGRYMKSGYVASGPKT 403
Query: 420 PSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472
LL V P ++G+FLDYE G +SFYN+ + +YTF+ F + PYF
Sbjct: 404 TQLL--PVVKPSKIGIFLDYELGDLSFYNMNDRSI-LYTFND-CFTEAVWPYF 452
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 221 bits (563), Expect = 1e-57
Identities = 149/478 (31%), Positives = 245/478 (51%), Gaps = 36/478 (7%)
Query: 2 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQT 61
T+ ++ ++REE+TC ICL+ + P++ +CGHSFC C+ + E SCP C
Sbjct: 3 TADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEE----HNTPLSCPECWR 58
Query: 62 SYQPGNLRPNRHL---ANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 118
+ + + + N L A+I R+LR VL + + K ++ G
Sbjct: 59 TLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV-- 116
Query: 119 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 178
+Q H + L E + ++EK QE L L+ +EA+ + +E+ + + +
Sbjct: 117 ---AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKT 173
Query: 179 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 238
+ + +E+ ++ L EQ +L+ LEQEEK+ +R + E L Q +SL ++I+ +E
Sbjct: 174 CKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIE 233
Query: 239 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 298
Q S E L++V ERSE L+ PEA T+L S+ R +K MLR
Sbjct: 234 SSSQSSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGMKEMLR---------K 283
Query: 299 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVLGSQHFSSGKHYW 357
+ ++TL+P TAN LVL+++ + V++ G++ P E+ +VLG+Q F+SG+HYW
Sbjct: 284 FSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYW 343
Query: 358 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 417
EV+V KT W +G+C +S+ + P + +IGL+ +Y +
Sbjct: 344 EVEVGNKTEWEVGICKDSV-----------SRKGNLPKPPGDLFSLIGLKIGDDYSLWV- 391
Query: 418 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPC 475
SSP + P +VGVFLDYE+G ++FYN T+ IY+F + F L P F+PC
Sbjct: 392 SSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESL-IYSFPQASFQEALRPIFSPC 448
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 218 bits (555), Expect = 1e-56
Identities = 140/472 (29%), Positives = 239/472 (50%), Gaps = 33/472 (6%)
Query: 6 LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 65
L ++ E C ICL+ L++P++I+CGH+FC++CI ++S + + CPVC+ Q
Sbjct: 7 LTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQE 62
Query: 66 GNLRPNRHLANIV---RRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 122
G+ R N L ++ + L+ KQ + LC H + L +FC+ED V+C LC +
Sbjct: 63 GHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQP 122
Query: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182
+H+GHH +E+ A Y+++F ++ LK + + +KL + +K + +E +R
Sbjct: 123 PDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE 182
Query: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 242
+ +EF L LDR +Q L +L +EEK + + + + +L+ +S + +
Sbjct: 183 LSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSE 242
Query: 243 GSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVD 302
S +ELL + + SE + ++ K P + R+ ++ + V+
Sbjct: 243 LSELELLSQIK-IFYESENESSPSIFSIHLKRDGCSFPPQYSALQRI------IKKFKVE 295
Query: 303 VTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS--VLGSQHFSSGKHYWEVD 360
+ L+P TA+ NL++++++++VRF K P K + VLG +F SG+H+WE++
Sbjct: 296 IILDPETAHPNLIVSEDKKRVRFTKRKQKVPG-FPKRFTVKPVVLGFPYFHSGRHFWEIE 354
Query: 361 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 420
V K+ W +G+C +SL PT A Q W I LQ + + +P
Sbjct: 355 VGDKSEWAIGICKDSL-PT----------KARRPSSAQQECWRIELQDDGYHAPGAFPTP 403
Query: 421 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472
LL V R +G+FLDYE G +SFYN+ I TF+ F L PYF
Sbjct: 404 LLL---EVKARAIGIFLDYEMGEISFYNMAEKSH-ICTFTD-TFTGPLRPYF 450
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 214 bits (546), Expect = 1e-55
Identities = 148/475 (31%), Positives = 235/475 (49%), Gaps = 55/475 (11%)
Query: 8 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 67
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
Query: 68 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 127
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
Query: 128 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 187
H ++E + Y+EK +S + L + ++ L + T WK++++ +R RI TEF
Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
Query: 188 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 247
++L N L E L++L +EE++ + + E L SL++LI ++ + Q T+E
Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
Query: 248 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLN 306
LLQ+ +V RSE + EA+ K++++ + P +K ML+ + V V L
Sbjct: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK---------RFQVAVNLA 286
Query: 307 PHTANLNLVLAKNRRQVRFVGAKVSGP------------------SCLEK--HYDCSVLG 346
TA+ LV ++ R V+ + S P + +E+ H C VLG
Sbjct: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPC-VLG 345
Query: 347 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYW-VIG 405
F+SGKHYWEV+ +GVC + + + + ++ Y +GYW +IG
Sbjct: 346 KNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIG 405
Query: 406 LQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFS 460
P RVGV+LD G VSFY+ + G ++TFS
Sbjct: 406 F-------------PGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS 446
>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
Length = 450
Score = 213 bits (542), Expect = 3e-55
Identities = 152/459 (33%), Positives = 231/459 (50%), Gaps = 49/459 (10%)
Query: 30 CGHSFCQACITPNGRESVIGQEGERS------CPVCQTSYQPGNLRPNRHLANIVRRLRE 83
CGH+FC+ACI + E G++G R CP C+ NL PNR L + ++
Sbjct: 4 CGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQ 62
Query: 84 VVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEK 143
PG Q K LC +H E L+LFCQ+D IC +C S+EHR H EE Q Y+ K
Sbjct: 63 ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLK 118
Query: 144 FQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELK 203
+E ++ L+ + L A + W+ +++ R RI EF ++ L EQR L+
Sbjct: 119 LEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQ 178
Query: 204 KLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWT 263
LE EE++ + E+ L Q SL L+ LE R +++LQD+ + R +
Sbjct: 179 ALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVS 238
Query: 264 LRKPE-ALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQ 322
++ PE A PT+ R++ R P +LR + DV + +A L+L ++ RQ
Sbjct: 239 VQCPEVAPPTRPRTVCRVPGQIEVLR---------GFLEDVVPDATSAYPYLLLYES-RQ 288
Query: 323 VRFVGAKVSGPSCLEKH----YDCSVLGSQHFSSGKHYWEV--DVAKKTAWILGVCSNSL 376
R++G+ G K Y C+V G FSSG+HYWEV ++ W LGVC +
Sbjct: 289 RRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSSGRHYWEVGMNITGDALWALGVCRD-- 345
Query: 377 GPTFSFNHFAQNHSAYSRYQ--PQSGYWVIGLQHNHEY-RAYEDSSPSLLLSMTVPPRRV 433
N S R P++G+WV+ L +Y + +P +L+ PP +
Sbjct: 346 -----------NVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLME---PPSHM 391
Query: 434 GVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472
G+FLD+EAG VSFY+V++ G ++T+S+ FP L P+F
Sbjct: 392 GIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPFF 429
>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
Length = 511
Score = 206 bits (524), Expect = 4e-53
Identities = 152/500 (30%), Positives = 238/500 (47%), Gaps = 50/500 (10%)
Query: 8 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS--------CPVC 59
+++ E TC ICLEL EP+S++CGHSFC+ACI G G + CP C
Sbjct: 22 ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81
Query: 60 QTSYQPGNLRPNRHLANIVRRLREVVL---GPGK--------QLKAVLCADHGEKLQLFC 108
+ +P LRPNR LA + LR L PG+ + A C HGE +L+C
Sbjct: 82 REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141
Query: 109 QEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREK 168
Q+DG+ IC +C+R++EHR H ++E QE +E + L+ LK E ++ E + +++
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201
Query: 169 KTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQ 228
QM E+ ++ EF LR L E R L +LE+ ++ + E L +
Sbjct: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261
Query: 229 SLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS-----MFRAPDL 283
L +L S ++ Q ++ LQ+ R KP + +++++ + L
Sbjct: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVL 321
Query: 284 KRMLRVCRELTDVQSYW-----VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK 338
K ML+ +E D++ V++TL+P TAN L+L+ + + VR +G +
Sbjct: 322 KGMLKKFKE--DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVR-LGERAQDLPNHPC 378
Query: 339 HYDCS--VLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ 396
+D + VL S FSSG+H+WEV+V K W GV S+ + +
Sbjct: 379 RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESV-----------RRKGLTPFT 427
Query: 397 PQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPI 456
P+ G W + L + +Y A S L + RV V LD E G VSFY V + +
Sbjct: 428 PEEGVWALQL-NGGQYWAVTSPERSPLSCGHL--SRVRVALDLEVGAVSFYAVEDMRH-L 483
Query: 457 YTFSKYYFPTTLCPYFNPCN 476
YTF + F + P F+ C+
Sbjct: 484 YTF-RVNFQERVFPLFSVCS 502
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 201 bits (510), Expect = 2e-51
Identities = 148/501 (29%), Positives = 235/501 (46%), Gaps = 81/501 (16%)
Query: 8 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 67
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
Query: 68 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 127
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
Query: 128 HHTFLVEEVAQEY--------------------------QEKFQESLKKLKNEEQEAEKL 161
H ++E + Y +EK +S + L + ++ L
Sbjct: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
Query: 162 TAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 221
+ T WK++++ +R RI TEF++L N L E L++L +EE++ + + E
Sbjct: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
Query: 222 DLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRA 280
L SL++LI ++ + Q T+ELLQ+ +V RSE + EA+ K++++ +
Sbjct: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQI 295
Query: 281 PDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGP------- 333
P +K ML+ + V V L TA+ LV ++ R V+ + S P
Sbjct: 296 PLMKEMLK---------RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWN 346
Query: 334 -----------SCLEK--HYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTF 380
+ +E+ H C VLG F+SGKHYWEV+ +GVC +
Sbjct: 347 YFAGWRNPQKTAFVERFQHLPC-VLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGIT 405
Query: 381 SFNHFAQNHSAYSRYQPQSGYW-VIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDY 439
+ + + ++ Y +GYW +IG P RVGV+LD
Sbjct: 406 DRSKMSPDVGIWAIYWSAAGYWPLIGF-------------PGTPTQQEPALHRVGVYLDR 452
Query: 440 EAGTVSFYNVTNHGFPIYTFS 460
G VSFY+ + G ++TFS
Sbjct: 453 GTGNVSFYSAVD-GVHLHTFS 472
>gi|4557743 Mediterranean fever protein [Homo sapiens]
Length = 781
Score = 199 bits (505), Expect = 6e-51
Identities = 149/483 (30%), Positives = 223/483 (46%), Gaps = 61/483 (12%)
Query: 16 PICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ---PGNLRPNR 72
P C +P+ C C +G G CP CQ S++ PG+L P +
Sbjct: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSP-GCPRCQDSHERKSPGSLSP-Q 370
Query: 73 HLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFL 132
L R L++V L LFC++ + IC +C SQEH+GH
Sbjct: 371 PLPQCKRHLKQVQL-------------------LFCEDHDEPICLICSLSQEHQGHRVRP 411
Query: 133 VEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRN 192
+EEVA E+++K Q+ L+ LK + E+ ++ EK S+ Q E + R+Q + Q+
Sbjct: 412 IEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471
Query: 193 ILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDV 252
L++ E + LE + +I + + + L LI +LE + S ELLQD+
Sbjct: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
Query: 253 SDVTERS------EFWTLRKPEALPTKL-----RSMFRAPDLKRMLRVCR---------E 292
D+ R+ E WT P+ + K+ +S F K R E
Sbjct: 532 GDILHRAKTVPVPEKWT--TPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPE 589
Query: 293 LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC-SVLGSQHFS 351
L Q++ V+V L+ TA NL+ + + + VR P ++ C VLGS F
Sbjct: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649
Query: 352 SGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 411
SG+ YWEV+V KTAWILG C S+ + P++GYWV+ + +E
Sbjct: 650 SGRRYWEVEVGDKTAWILGACKTSI-----------SRKGNMTLSPENGYWVVIMMKENE 698
Query: 412 YRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPY 471
Y+A S P L + PP+RVG+F+DY G++SFYNVT IYTF+ F L P
Sbjct: 699 YQA--SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSH-IYTFASCSFSGPLQPI 755
Query: 472 FNP 474
F+P
Sbjct: 756 FSP 758
>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
Length = 630
Score = 198 bits (504), Expect = 8e-51
Identities = 136/444 (30%), Positives = 217/444 (48%), Gaps = 34/444 (7%)
Query: 55 SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 111
+CP C+ S+ + RPN LAN+V+ +R++ PG+ + +C H E L+LFC+ D
Sbjct: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241
Query: 112 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 171
+ IC +C S+ H+ H +EEV QEY+ K Q ++ L+ + +K+ A + T
Sbjct: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301
Query: 172 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 231
K+QM+ E + +EF +L L + ++L + + L A + L Q L
Sbjct: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361
Query: 232 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEAL---PTKLRSMFRAPD--LKRM 286
L+++ + R Q + LLQD+ + R E L+ PE P + S D +++M
Sbjct: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421
Query: 287 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVL 345
R+ Q+ VD+TL+P TA+ L+L+ +RR VR + ++ DC VL
Sbjct: 422 SRMF-----CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476
Query: 346 GSQHFSSGKHYWEVDVAKKTAWILGVCSNSL---------------GPTFSFNHFAQNHS 390
G+Q F SG+HYWEV+V + W +G S G S H +
Sbjct: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536
Query: 391 AYSRYQP--QSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYN 448
+ QP Q W +G + Y+A + S+ LLS + PRR GV+LDYEAG + FYN
Sbjct: 537 LHLPQQPLLQREVWCVG-TNGKRYQA-QSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594
Query: 449 VTNHGFPIYTFSKYYFPTTLCPYF 472
++TFS + + P+F
Sbjct: 595 AETLAH-VHTFSAAFLGERVFPFF 617
Score = 51.2 bits (121), Expect = 2e-06
Identities = 19/40 (47%), Positives = 28/40 (70%)
Query: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 40
MT + ++EE C ICL+ T+P+SI CGH+FC+ C+T
Sbjct: 6 MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,524,034
Number of Sequences: 37866
Number of extensions: 966963
Number of successful extensions: 6577
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 599
Number of HSP's that attempted gapping in prelim test: 4202
Number of HSP's gapped (non-prelim): 2078
length of query: 488
length of database: 18,247,518
effective HSP length: 106
effective length of query: 382
effective length of database: 14,233,722
effective search space: 5437281804
effective search space used: 5437281804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.