Guide to the Human Genome
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Name: CDKN1A Sequence: fasta or formatted (164aa) NCBI GI: 17978495
Description:

cyclin-dependent kinase inhibitor 1A

Referenced in:

Cyclins and Related Functions
p53 Pathway
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt mRNA [164aa] cyclin-dependent kinase inhibitor 1A
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5          9           1
 C cysteine            3.0          5           1
 D aspartate           6.7         11           1
 E glutamate           7.3         12           2
 F phenylalanine       3.7          6           1
 G glycine            12.2         20           3
 H histidine           1.2          2           1
 I isoleucine          1.2          2           1
 K lysine              3.7          6           1
 L leucine             9.1         15           2
 M methionine          1.8          3           1
 N asparagine          1.2          2           1
 P proline             7.9         13           1
 Q glutamine           4.3          7           1
 R arginine           12.2         20           2
 S serine              7.9         13           1
 T threonine           4.9          8           1
 V valine              3.7          6           1
 W tryptophan          1.2          2           1
 Y tyrosine            1.2          2           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cyclin-dependent kinase inhibitor 1A 
CDKN1A                1.000   cyclin-dependent kinase inhibitor 1A 
CDKN1B                0.125   cyclin-dependent kinase inhibitor 1B 
CDKN1C                0.094   cyclin-dependent kinase inhibitor 1C isoform b [Hom...
CDKN1C                0.094   cyclin-dependent kinase inhibitor 1C isoform b [Hom...
CDKN1C                0.094   cyclin-dependent kinase inhibitor 1C isoform a 
MN1                   0.019   meningioma  1 
PLEKHM2               0.019   pleckstrin homology domain containing, family M (wi...
CCDC96                0.019   coiled-coil domain containing 96 
LOC100129786          0.019   PREDICTED: hypothetical protein LOC100129786 
LOC100129786          0.019   PREDICTED: hypothetical protein LOC100129786 
LOC100129786          0.019   PREDICTED: hypothetical protein LOC100129786 
ANO8                  0.016   anoctamin 8 
CELSR3                0.016   cadherin EGF LAG seven-pass G-type receptor 3 [Homo...
PRB4                  0.016   proline-rich protein BstNI subfamily 4 precursor [Ho...
LOC729196             0.013   PREDICTED: similar to unc-93 homolog B1 (C. elegans...
LOC100293985          0.013   PREDICTED: hypothetical protein 
LOC100289986          0.013   PREDICTED: hypothetical protein XP_002346657 
LOC100288009          0.013   PREDICTED: hypothetical protein XP_002342502 
KIAA0802              0.013   hypothetical protein LOC23255 
CEP170                0.013   centrosomal protein 170kDa isoform beta 
CEP170                0.013   centrosomal protein 170kDa isoform alpha 
CEP170                0.013   centrosomal protein 170kDa isoform gamma 
CRAMP1L               0.013   Crm, cramped-like 
CHUK                  0.013   conserved helix-loop-helix ubiquitous kinase 
C16orf13              0.013   hypothetical protein LOC84326 isoform g 
SHANK1                0.013   SH3 and multiple ankyrin repeat domains 1 
IRS2                  0.009   insulin receptor substrate 2 
SLC32A1               0.009   solute carrier family 32, member 1 
SYNJ1                 0.009   synaptojanin 1 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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