Guide to the Human Genome
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Name: PLEKHM2 Sequence: fasta or formatted (1019aa) NCBI GI: 221139728
Description:

pleckstrin homology domain containing, family M (with RUN domain) member 2

Referenced in:

Inositol Pathways
Additional Interaction Domain Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         62           2
 C cysteine            2.9         30           2
 D aspartate           6.5         66           2
 E glutamate           8.5         87           3
 F phenylalanine       2.9         30           2
 G glycine             6.1         62           4
 H histidine           2.6         27           2
 I isoleucine          2.6         27           1
 K lysine              4.4         45           4
 L leucine            11.3        115           4
 M methionine          1.7         17           1
 N asparagine          2.5         25           2
 P proline             6.9         70           2
 Q glutamine           4.5         46           2
 R arginine            4.6         47           2
 S serine             10.3        105           3
 T threonine           5.8         59           2
 V valine              5.7         58           2
 W tryptophan          1.2         12           1
 Y tyrosine            2.8         29           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pleckstrin homology domain containing, family M (wi... 
PLEKHM1               0.021   pleckstrin homology domain containing, family M (wit...
RUNDC2A               0.019   RUN domain containing 2A 
NOLC1                 0.013   nucleolar and coiled-body phosphoprotein 1 
RUFY1                 0.012   RUN and FYVE domain-containing 1 isoform b 
RUFY1                 0.012   RUN and FYVE domain-containing 1 isoform b 
RUFY1                 0.012   RUN and FYVE domain-containing 1 isoform a 
MLL2                  0.012   myeloid/lymphoid or mixed-lineage leukemia 2 
DSPP                  0.012   dentin sialophosphoprotein preproprotein 
GTF2F1                0.011   general transcription factor IIF, polypeptide 1, 74...
RUNDC3A               0.011   RUN domain containing 3A isoform 3 
RUNDC3B               0.011   RUN domain containing 3B isoform c 
RUNDC3B               0.011   RUN domain containing 3B isoform b 
MUC12                 0.010   PREDICTED: mucin 12 
RUNDC3A               0.010   RUN domain containing 3A isoform 1 
RUNDC3A               0.010   RUN domain containing 3A isoform 2 
LOC100289777          0.010   PREDICTED: hypothetical protein XP_002348316 
NEFH                  0.009   neurofilament, heavy polypeptide 200kDa 
LIPE                  0.008   hormone-sensitive lipase 
RUFY3                 0.008   RUN and FYVE domain containing 3 isoform 2 
RUFY3                 0.008   RUN and FYVE domain containing 3 isoform 1 
RUFY3                 0.008   RUN and FYVE domain containing 3 isoform 3 
CCDC88C               0.008   DVL-binding protein DAPLE 
LOC400986             0.008   PREDICTED: protein immuno-reactive with anti-PTH po...
VCX                   0.008   variable charge, X chromosome 
RUNDC3B               0.008   RUN domain containing 3B isoform a 
LOC100133714          0.008   PREDICTED: similar to Mucin-12, partial 
RUFY2                 0.008   RUN and FYVE domain-containing 2 isoform a 
MUC12                 0.007   PREDICTED: mucin 12 
VCX3A                 0.007   variable charge, X-linked 3A 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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