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Search of human proteins with 17402900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17402900 far upstream element-binding protein [Homo sapiens]
(644 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17402900 far upstream element-binding protein [Homo sapiens] 1357 0.0
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 819 0.0
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 608 e-174
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 85 2e-16
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 84 3e-16
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 84 3e-16
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 82 2e-15
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 80 6e-15
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 78 2e-14
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 76 1e-13
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 76 1e-13
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 75 2e-13
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 75 2e-13
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 75 2e-13
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 74 3e-13
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 74 3e-13
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 74 3e-13
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 74 4e-13
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 73 7e-13
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 73 7e-13
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 73 7e-13
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 73 7e-13
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 73 7e-13
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 73 7e-13
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 72 2e-12
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 72 2e-12
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 72 2e-12
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 71 3e-12
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 71 3e-12
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 70 5e-12
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 1357 bits (3512), Expect = 0.0
Identities = 644/644 (100%), Positives = 644/644 (100%)
Query: 1 MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGY 60
MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGY
Sbjct: 1 MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGY 60
Query: 61 GGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGG 120
GGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGG
Sbjct: 61 GGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGG 120
Query: 121 EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHG 180
EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHG
Sbjct: 121 EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHG 180
Query: 181 DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGD 240
DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGD
Sbjct: 181 DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGD 240
Query: 241 PYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKK 300
PYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKK
Sbjct: 241 PYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKK 300
Query: 301 IQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRG 360
IQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRG
Sbjct: 301 IQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRG 360
Query: 361 RGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNA 420
RGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNA
Sbjct: 361 RGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNA 420
Query: 421 DPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTP 480
DPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTP
Sbjct: 421 DPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTP 480
Query: 481 MGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAY 540
MGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAY
Sbjct: 481 MGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAY 540
Query: 541 YAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP 600
YAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP
Sbjct: 541 YAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP 600
Query: 601 TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ 644
TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ
Sbjct: 601 TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ 644
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 819 bits (2116), Expect = 0.0
Identities = 432/700 (61%), Positives = 491/700 (70%), Gaps = 90/700 (12%)
Query: 9 PPSSGSAGGGGGGGGGGG------------------VNDAFKDALQRARQIAAKIGGDAG 50
PP +G GGGG GGGG G DAF DA+QRARQIAAKIGGDA
Sbjct: 34 PPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAA 93
Query: 51 TSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVP 108
T++N++ D+G+GGQKR LEDGDQP++KK+A Q DS +QL P+H R+ MTEEY+VP
Sbjct: 94 TTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIH-PPPRTSMTEEYRVP 152
Query: 109 DGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIV 168
DGMVG IIGRGGEQI++IQQ+SGCK+QI+PDSGGLPERS LTG PESVQ AK +LD IV
Sbjct: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIV 212
Query: 169 EKGRPAP--GFHH--GDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224
+GR P FH G VQEIMIPA KAGLVIGKGGETIKQLQERAGVKM++IQD
Sbjct: 213 SRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQD 272
Query: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEYGSRIGGNEGIDVPI 282
G QNT DKPLRI GDPYKVQQA EMV++++ RDQGGF + RNEYGSRIGG GIDVP+
Sbjct: 273 GSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEYGSRIGG--GIDVPV 329
Query: 283 PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDL 342
PR +VG+VIGR+GEMIKKIQNDAGVRIQFK DDGT PE+IA I GPPDRC+HAA II DL
Sbjct: 330 PRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDL 389
Query: 343 LRSVQAGNPGGPG-----PGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGE 397
L+S+++G PG PG PGGRGRGRGQGNW GPPGG E F +PT K GL+IG+GGE
Sbjct: 390 LQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSIPTHKCGLVIGRGGE 445
Query: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPP 457
+K+I+QQ+GA +E+ R PPN DPN KLF IRG+PQQID+A+QLIEEKI GP+ P+GP
Sbjct: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP- 504
Query: 458 VPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---PPAPYAPQGWGNAY 514
PG PGP PMGP+NP P+N GPPG PH PP Y PQGWGN Y
Sbjct: 505 -------------GPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTY 551
Query: 515 PHWQQQAPPDPAK---AGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQ 571
P WQ AP DP+K A DPN AAWAAYY+HYYQ QPP P AP QG+
Sbjct: 552 PQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQ---QPPGPVPGPAPAPAAPPAQGEP 607
Query: 572 QNPAPAGQVDYTKAWEEYYKKMGQAVPAP---------------------------TGAP 604
P P GQ DYTKAWEEYYKK+GQ P GAP
Sbjct: 608 PQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP 667
Query: 605 PGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ 644
PG QPDYSAAWAEYYRQQAAYY QT G PQ PP QGQ
Sbjct: 668 PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707
Score = 37.4 bits (85), Expect = 0.043
Identities = 34/93 (36%), Positives = 38/93 (40%), Gaps = 17/93 (18%)
Query: 448 GGPVNPLGPPVPHGPHGVPGPHG------PPGPPGPGTPMGPYNPAPYNPGPPGPAPHGP 501
GGP PP P P G G G PPGPPG G G P GP G + GP
Sbjct: 7 GGP-----PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG---GGPGGGGPGGGSAGGP 58
Query: 502 PAPYAPQGWG---NAYPHWQQQAPPDPAKAGTD 531
P G G +A+ Q+A AK G D
Sbjct: 59 SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 608 bits (1567), Expect = e-174
Identities = 340/617 (55%), Positives = 403/617 (65%), Gaps = 82/617 (13%)
Query: 29 DAFKDALQRARQIAAKIGGDAGTSLNSND-------YGYGGQKRPLEDGDQPDAKKVAPQ 81
+ F DAL R RQIAAKI D+ LN++ YGYG QKRPL+DG
Sbjct: 17 EGFVDALHRVRQIAAKI--DSIPHLNNSTPLVDPSVYGYGVQKRPLDDG----------- 63
Query: 82 NDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSG 141
G QL + Q R+V+TEE+KVPD MVGFIIGRGGEQISRIQ ESGCKIQIA +S
Sbjct: 64 ---VGNQLGALVHQ--RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS 118
Query: 142 GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVI 201
G+PER C+LTGTPES++ AKRLL QIV++ R PGFH+ + +QEI+IPASK GLVI
Sbjct: 119 GIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVI 178
Query: 202 GKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIR--DQG 259
G+GGETIKQLQER GVKMVMIQDGP TGADKPLRITGD +KVQQA+EMVLE+IR DQ
Sbjct: 179 GRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238
Query: 260 GFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319
FR VR ++ SR+GG I+V +PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDG +P
Sbjct: 239 DFRGVRGDFNSRMGGGS-IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP 297
Query: 320 ERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEF 379
ER AQ+ GPPDRCQHAA II++L+ + Q + G RGRGRG+G+W++G PGG+QE
Sbjct: 298 ERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEI 357
Query: 380 NFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYA 439
+ VP K GL+IGKGGE IKSI+QQSGA +ELQRNPPPN+DPN++ FTIRG PQQI+ A
Sbjct: 358 TYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVA 417
Query: 440 RQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGP---PGPGTPMGPYNPAPYNPGPPGP 496
RQLI+EK+GG LG P G P PP P + P A N P
Sbjct: 418 RQLIDEKVGG--TNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHST 475
Query: 497 APHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAP 556
GPPA + QGWG+ Y WQQ P+ QQ+QP + P
Sbjct: 476 PVSGPPA-FLTQGWGSTYQAWQQPTQQVPS--------------------QQSQPQSSQP 514
Query: 557 AGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAV-PAPTGAPPGGQPDYSAAW 615
+Y+KAWE+YYKK A AP + P PDY+ AW
Sbjct: 515 ------------------------NYSKAWEDYYKKQSHAASAAPQASSP---PDYTMAW 547
Query: 616 AEYYRQQAAYYAQTSPQ 632
AEYYRQQ A+Y QT Q
Sbjct: 548 AEYYRQQVAFYGQTLGQ 564
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 84.7 bits (208), Expect = 2e-16
Identities = 96/312 (30%), Positives = 109/312 (34%), Gaps = 65/312 (20%)
Query: 345 SVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQ 404
S+ AGNP GP P G GN GPP P GK +GG
Sbjct: 30 SLIAGNPQGPSPQG-------GNKPQGPP---------PPPGKPQGPPPQGGN-----KP 68
Query: 405 QSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHG-PH 463
Q + PPP D + + G PQ G P GPP P G P
Sbjct: 69 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ---------GPPPQGGNQPQGPPPPPGKPQ 119
Query: 464 GVP--GPHGPPGPPGPGTPMG--PYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQ 519
G P G + P GPP PG P G P +P P P GPP PQG GN Q
Sbjct: 120 GPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP----PQG-GNQ----PQ 170
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAP-----TTTQTNGQGDQQNP 574
PP P K P + Q PPP P G P + + + G Q P
Sbjct: 171 GPPPPPGKPQGPPPQGG--------KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGP 222
Query: 575 APAGQVDYTKAWEEYYKKMG---QAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSP 631
P G K G Q P G PP G+P A Q A SP
Sbjct: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSA-----RSP 277
Query: 632 QGMPQHPPAPQG 643
G PQ PP +G
Sbjct: 278 PGKPQGPPQQEG 289
Score = 75.1 bits (183), Expect = 2e-13
Identities = 89/301 (29%), Positives = 103/301 (34%), Gaps = 63/301 (20%)
Query: 349 GNPGGPGP-GGRGRG-RGQGNWNMGPP--GGLQEFNFIVPTGKTGLIIGKGGETIKSISQ 404
G P GP P G + R R GPP GG Q P GK +
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP-----------QGPPP 123
Query: 405 QSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHG 464
Q G R + PPP P +G P Q D +R P +P G P P G
Sbjct: 124 QGGNR---PQGPPPPGKP-------QGPPPQGDKSRS--------PRSPPGKPQGPPPQG 165
Query: 465 VPGPHGPPGPPG-PGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPP 523
P GPP PPG P P P P PPG P GPP P + + P + Q P
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG-KPQGPP-PQGDKSRSSQSPPGKPQGP- 222
Query: 524 DPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYT 583
P + G P Q PPP P G P G Q P P G+
Sbjct: 223 -PPQGGNQP--------------QGPPPPPGKPQGPP----PQGGNKPQGPPPPGKPQGP 263
Query: 584 KAWEEYYKKMGQAVPAPTGAPP---GGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPA 640
A + ++ P PP G P A QQ Q P G PQ PP
Sbjct: 264 PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ----PQAPPAGQPQGPPR 319
Query: 641 P 641
P
Sbjct: 320 P 320
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/171 (30%), Positives = 58/171 (33%), Gaps = 56/171 (32%)
Query: 341 DLLRSVQA--GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGET 398
D RS Q+ G P GP P G GN GPP P GK +GG
Sbjct: 207 DKSRSSQSPPGKPQGPPPQG-------GNQPQGPPP---------PPGKPQGPPPQGGNK 250
Query: 399 IKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPV 458
+ PPP P +G P Q Q P P GPP
Sbjct: 251 --------------PQGPPPPGKP-------QGPPAQGGSKSQSARSP---PGKPQGPPQ 286
Query: 459 PHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQG 509
G + P GPP PP G P P PP P GPP P PQG
Sbjct: 287 QEGNN----PQGPP-PPAGGNPQQP-------QAPPAGQPQGPPRP--PQG 323
Score = 44.3 bits (103), Expect = 4e-04
Identities = 48/170 (28%), Positives = 58/170 (34%), Gaps = 43/170 (25%)
Query: 485 NPAPYNPGPPGPAPHG-------PPAPYAPQG----WGNAYPHWQQQAPPDPAKAGTDPN 533
+P+ P GP+P G PP P PQG GN + Q PP P K P
Sbjct: 28 SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGN-----KPQGPPPPGKPQGPPP 82
Query: 534 SAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKM 593
+ + PP P G P G Q P P G+
Sbjct: 83 QGD--------KSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGPPP-------- 123
Query: 594 GQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQG 643
Q P G PP G+P + R + SP G PQ PP PQG
Sbjct: 124 -QGGNRPQGPPPPGKPQGPPPQGDKSR------SPRSPPGKPQGPP-PQG 165
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 84.3 bits (207), Expect = 3e-16
Identities = 101/408 (24%), Positives = 163/408 (39%), Gaps = 80/408 (19%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEK- 170
VG IIG+ GE + RI+++S +I I+ G PER +TG+ +V A ++ +++
Sbjct: 29 VGSIIGKKGETVKRIREQSSARITIS--EGSCPERITTITGSTAAVFHAVSMIAFKLDED 86
Query: 171 --GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQN 228
PA G + P ++IPAS+ G +IGK G IK+++E G ++ + D N
Sbjct: 87 LCAAPANGGNVSRPP--VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN 144
Query: 229 TGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAV 287
+ ++ + ++G P + + +I + +G +P P ++
Sbjct: 145 S-TERAVTVSGVPDAIILCVRQICAVILESPP---------------KGATIPYHPSLSL 188
Query: 288 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQ 347
G V+ + + G +Q + TP A++T HA T SV
Sbjct: 189 GTVL---------LSANQGFSVQGQYG-AVTP---AEVTKLQQLSSHAVPFATP---SVV 232
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
G + P F+VP G +IG+ G I I Q SG
Sbjct: 233 PG--------------------LDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSG 272
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A I++ + ++ TI G+P I A+ LI + + G P +P
Sbjct: 273 AHIKIGNQAEGAGERHV---TITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPA 329
Query: 468 PHGPP------GPPG-PGTPMG-------PYNPAPY---NPGPPGPAP 498
P PP PPG GTP P P+ P PGP P
Sbjct: 330 PFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPP 377
Score = 57.0 bits (136), Expect = 5e-08
Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Query: 50 GTSLNSNDYGYG--GQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKV 107
GT L S + G+ GQ + + ++++ F T ++E+ V
Sbjct: 189 GTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLV 248
Query: 108 PDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQI 167
P+ ++G +IGR G +IS I+Q SG I+I + G ER +TG+P S+ A+ L+
Sbjct: 249 PNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITAC 308
Query: 168 VEKGRPAPGFHHGDGPGN 185
+E + G P +
Sbjct: 309 LETAKSTSGGTPSSAPAD 326
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/213 (21%), Positives = 84/213 (39%), Gaps = 63/213 (29%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T +P G +IG+ G +I I++ +G ++Q+A D LP ER+ ++G
Sbjct: 98 SRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDL--LPNSTERAVTVSGV 155
Query: 154 PESVQSAKRLLDQIVEKGRP---------------------------------------- 173
P+++ R + ++ + P
Sbjct: 156 PDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTK 215
Query: 174 ------------APGFHHGDGPG--NAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM 219
P G PG + QE ++P G VIG+ G I ++++ +G
Sbjct: 216 LQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAH- 274
Query: 220 VMIQDGPQNTGA-DKPLRITGDPYKVQQAKEMV 251
I+ G Q GA ++ + ITG P + A+ ++
Sbjct: 275 --IKIGNQAEGAGERHVTITGSPVSIALAQYLI 305
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 371 GPPGGLQE---------FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNAD 421
G GGL+E ++ + G IIGK GET+K I +QS ARI + P
Sbjct: 3 GSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE-- 60
Query: 422 PNMKLFTIRGTPQQIDYARQLIEEKI 447
++ TI G+ + +A +I K+
Sbjct: 61 ---RITTITGSTAAVFHAVSMIAFKL 83
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 84.3 bits (207), Expect = 3e-16
Identities = 101/408 (24%), Positives = 163/408 (39%), Gaps = 80/408 (19%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEK- 170
VG IIG+ GE + RI+++S +I I+ G PER +TG+ +V A ++ +++
Sbjct: 29 VGSIIGKKGETVKRIREQSSARITIS--EGSCPERITTITGSTAAVFHAVSMIAFKLDED 86
Query: 171 --GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQN 228
PA G + P ++IPAS+ G +IGK G IK+++E G ++ + D N
Sbjct: 87 LCAAPANGGNVSRPP--VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN 144
Query: 229 TGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAV 287
+ ++ + ++G P + + +I + +G +P P ++
Sbjct: 145 S-TERAVTVSGVPDAIILCVRQICAVILESPP---------------KGATIPYHPSLSL 188
Query: 288 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQ 347
G V+ + + G +Q + TP A++T HA T SV
Sbjct: 189 GTVL---------LSANQGFSVQGQYG-AVTP---AEVTKLQQLSSHAVPFATP---SVV 232
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
G + P F+VP G +IG+ G I I Q SG
Sbjct: 233 PG--------------------LDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSG 272
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A I++ + ++ TI G+P I A+ LI + + G P +P
Sbjct: 273 AHIKIGNQAEGAGERHV---TITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPA 329
Query: 468 PHGPP------GPPG-PGTPMG-------PYNPAPY---NPGPPGPAP 498
P PP PPG GTP P P+ P PGP P
Sbjct: 330 PFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPP 377
Score = 57.0 bits (136), Expect = 5e-08
Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Query: 50 GTSLNSNDYGYG--GQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKV 107
GT L S + G+ GQ + + ++++ F T ++E+ V
Sbjct: 189 GTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLV 248
Query: 108 PDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQI 167
P+ ++G +IGR G +IS I+Q SG I+I + G ER +TG+P S+ A+ L+
Sbjct: 249 PNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITAC 308
Query: 168 VEKGRPAPGFHHGDGPGN 185
+E + G P +
Sbjct: 309 LETAKSTSGGTPSSAPAD 326
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/213 (21%), Positives = 84/213 (39%), Gaps = 63/213 (29%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T +P G +IG+ G +I I++ +G ++Q+A D LP ER+ ++G
Sbjct: 98 SRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDL--LPNSTERAVTVSGV 155
Query: 154 PESVQSAKRLLDQIVEKGRP---------------------------------------- 173
P+++ R + ++ + P
Sbjct: 156 PDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTK 215
Query: 174 ------------APGFHHGDGPG--NAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM 219
P G PG + QE ++P G VIG+ G I ++++ +G
Sbjct: 216 LQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAH- 274
Query: 220 VMIQDGPQNTGA-DKPLRITGDPYKVQQAKEMV 251
I+ G Q GA ++ + ITG P + A+ ++
Sbjct: 275 --IKIGNQAEGAGERHVTITGSPVSIALAQYLI 305
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 371 GPPGGLQE---------FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNAD 421
G GGL+E ++ + G IIGK GET+K I +QS ARI + P
Sbjct: 3 GSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE-- 60
Query: 422 PNMKLFTIRGTPQQIDYARQLIEEKI 447
++ TI G+ + +A +I K+
Sbjct: 61 ---RITTITGSTAAVFHAVSMIAFKL 83
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 82.0 bits (201), Expect = 2e-15
Identities = 88/358 (24%), Positives = 149/358 (41%), Gaps = 59/358 (16%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLL-----DQ 166
VG IIG+ GE + ++++ESG +I I+ G PER +TG +++ A ++ +
Sbjct: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
Query: 167 IVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226
I+ +P +++PAS+ G +IGKGG IK+++E G ++ + D
Sbjct: 115 IINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDML 170
Query: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRF 285
N+ ++ + I+G P + Q + + ++ + +G +P P+
Sbjct: 171 PNS-TERAVTISGTPDAIIQCVKQICVVMLE---------------SPPKGATIPYRPKP 214
Query: 286 AVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIA--QITGPPDRCQHAAEIITDLL 343
A VI G+ IQ + PD T ++A Q PP
Sbjct: 215 ASTPVIFAGGQAY-TIQGQYAIP---HPDQLTKLHQLAMQQTPFPP-------------- 256
Query: 344 RSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGL------QEFNFIVPTGKTGLIIGKGGE 397
+ NP PG + MG GL +P G IIG+ G
Sbjct: 257 --LGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGT 314
Query: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
I I Q SGA+I++ +++ + TI GTP I A+ LI ++ V +G
Sbjct: 315 KINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARLTSEVTGMG 369
Score = 74.7 bits (182), Expect = 2e-13
Identities = 57/188 (30%), Positives = 89/188 (47%), Gaps = 32/188 (17%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIIT-----D 341
VG +IG+ GE +KK++ ++G RI +G PERI ITGP D A +I D
Sbjct: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
Query: 342 LLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKS 401
++ S+ + +P PP L+ +VP + G +IGKGG IK
Sbjct: 115 IINSM-SNSPA----------------TSKPPVTLR---LVVPASQCGSLIGKGGSKIKE 154
Query: 402 ISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPH 460
I + +GA++++ + PN+ + TI GTP I +Q+ + P P G +P+
Sbjct: 155 IRESTGAQVQVAGDMLPNS--TERAVTISGTPDAIIQCVKQICVVMLESP--PKGATIPY 210
Query: 461 GPHGVPGP 468
P P
Sbjct: 211 RPKPASTP 218
Score = 57.0 bits (136), Expect = 5e-08
Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 11/113 (9%)
Query: 53 LNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMV 112
L + + G+K PL ++ A+ + Q+ P T E +P+ ++
Sbjct: 257 LGQTNPAFPGEKLPLHSSEE--AQNLMGQSSGLDASPP---------ASTHELTIPNDLI 305
Query: 113 GFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLD 165
G IIGR G +I+ I+Q SG +I+IA + G ER +TGTP ++ A+ L++
Sbjct: 306 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 358
Score = 56.2 bits (134), Expect = 9e-08
Identities = 61/266 (22%), Positives = 109/266 (40%), Gaps = 37/266 (13%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
S+ +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ ++GT
Sbjct: 126 SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDM--LPNSTERAVTISGT 183
Query: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P++ +Q K++ ++E P G P A ++ +A + +G I
Sbjct: 184 PDAIIQCVKQICVVMLES--PPKGATIPYRPKPASTPVIFAGGQAYTI--QGQYAIPHPD 239
Query: 213 ERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRI 272
+ + + +Q P G+ + ++E + +
Sbjct: 240 QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEA------------------QNLM 281
Query: 273 GGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIA 323
G + G+D + IP +G +IGR G I +I+ +G +I+ + ER
Sbjct: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341
Query: 324 QITGPPDRCQHAAEIITDLLRSVQAG 349
ITG P A +I L S G
Sbjct: 342 TITGTPANISLAQYLINARLTSEVTG 367
Score = 47.0 bits (110), Expect = 5e-05
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 14/165 (8%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GET+K+++E +G + + I +G ++ + ITG + +A
Sbjct: 50 LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEG---NCPERIVTITGPTDAIFKAFA 105
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNE---GIDVPIPRFAVGIVIGRNGEMIKKIQNDAG 306
M+ + ++ N + ++ + + +P G +IG+ G IK+I+ G
Sbjct: 106 MIAYKFEE-----DIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTG 160
Query: 307 VRIQFKPDD-GTTPERIAQITGPPDR-CQHAAEIITDLLRSVQAG 349
++Q D + ER I+G PD Q +I +L S G
Sbjct: 161 AQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKG 205
Score = 36.2 bits (82), Expect = 0.096
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GET+K + ++SGARI + P ++ TI G I A +I K
Sbjct: 56 EVGSIIGKKGETVKKMREESGARINISEGNCPE-----RIVTITGPTDAIFKAFAMIAYK 110
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 80.1 bits (196), Expect = 6e-15
Identities = 99/320 (30%), Positives = 115/320 (35%), Gaps = 59/320 (18%)
Query: 345 SVQAGNPGGPGPGGRGRGRGQGN---WNMGPP--GGLQEFNFIVPTGKTGLIIGKGGETI 399
S+ AGNP G P G + +G + GPP GG Q P GK +GG
Sbjct: 30 SLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-- 87
Query: 400 KSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVP 459
Q + PPP D + + G PQ G P GPP P
Sbjct: 88 ---KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ---------GPPPQGGNQPQGPPPP 135
Query: 460 HG-PHGVP--GPHGPPGPPGPGTPMGP----YNPAPYNPGPPGPAPHGPPAPYAPQGWGN 512
G P G P G + P GPP PG P GP N + + PPG P GPP PQG GN
Sbjct: 136 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPG-KPQGPP----PQG-GN 189
Query: 513 AYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ---- 568
Q PP P K P + Q PPP P G P Q
Sbjct: 190 Q----PQGPPPPPGKPQGPPPQGG--------NKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Query: 569 --GDQQNPAPAGQVDYTKAWEEYYKKMG---QAVPAPTGAPPGGQPDYSAAWAEYYRQQA 623
G Q P P G K G Q P G PP G+P + +
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-----QGGS 292
Query: 624 AYYAQTSPQGMPQHPPAPQG 643
+ SP G PQ PP PQG
Sbjct: 293 KSRSSRSPPGKPQGPP-PQG 311
Score = 75.5 bits (184), Expect = 1e-13
Identities = 97/323 (30%), Positives = 111/323 (34%), Gaps = 72/323 (22%)
Query: 349 GNPGGPGP-GGRGRG-RGQGNWNMGPP--GGLQEFNFIVPTGKTGLIIGKGGETIKSISQ 404
G P GP P G + R R GPP GG Q P GK +GG
Sbjct: 96 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK------ 149
Query: 405 QSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNP--------LGP 456
+ PPP P +G P Q D + G P P GP
Sbjct: 150 --------PQGPPPPGKP-------QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Query: 457 PVPHG-PHGVP--GPHGPPGPPGPGTPMGP----YNPAPYNPGPPGPAPHGPPAPYAPQG 509
P P G P G P G + P GPP PG P GP N + PPG P GPP PQG
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG-KPQGPP----PQG 249
Query: 510 WGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAP------TTT 563
GN Q PP P K P + Q PPP P G P + +
Sbjct: 250 -GNQ----PQGPPPPPGKPQGPPPQGG--------NKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 564 QTNGQGDQQNPAPAGQVDYTKAWEEYYKKMG---QAVPAPTGAPPGGQPDYSAAWAEYYR 620
+ G Q P P G K G Q P G PP G+P
Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356
Query: 621 QQAAYYAQTSPQGMPQHPPAPQG 643
+ A SP G PQ PP +G
Sbjct: 357 RSA-----RSPPGKPQGPPQQEG 374
Score = 75.1 bits (183), Expect = 2e-13
Identities = 90/309 (29%), Positives = 99/309 (32%), Gaps = 76/309 (24%)
Query: 349 GNPGGPGPGGRGRGRGQGN---WNMGPP--GGLQEFNFIVPTGKTGLIIGKGGETIKSIS 403
G P GP P G + R + GPP GG Q P GK +GG
Sbjct: 157 GKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK----- 211
Query: 404 QQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPH 463
+ PPP P +G P Q D Q P P GPP P
Sbjct: 212 ---------PQGPPPPGKP-------QGPPPQGDNKSQSARSP---PGKPQGPP----PQ 248
Query: 464 GVPGPHGPPGPPG-PGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAP 522
G P GPP PPG P P P P PPG P GPP + + P + Q P
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 523 PDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQ-----QNPAPA 577
P + G P Q PPP P G P QG Q P P
Sbjct: 308 PP--QGGNQP--------------QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 351
Query: 578 GQVDYTKAWEEYYKKMG---QAVPAPTGAPP--GGQPDYSAAWAEYYRQQAAYYAQTSPQ 632
G A K G Q P G PP GG P Q P
Sbjct: 352 GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP---------------QAPPA 396
Query: 633 GMPQHPPAP 641
G PQ PP P
Sbjct: 397 GQPQGPPRP 405
Score = 58.2 bits (139), Expect = 2e-08
Identities = 60/198 (30%), Positives = 66/198 (33%), Gaps = 66/198 (33%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
G P GP P G GN GPP P GK + Q G+
Sbjct: 261 GKPQGPPPQG-------GNKPQGPP----------PPGKP-----------QGPPPQGGS 292
Query: 409 RIELQRNPP--PNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHG--PHG 464
+ R+PP P P +G P P P GPP G P G
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGPPPP--------------PGKPQGPPPQGGNKPQG 338
Query: 465 VPGPHGPPGPPG------------PGTPMGPYNPAPYNP-GPPGPAPHGPPAPYAPQGWG 511
P P P GPP PG P GP NP GPP PA P P AP
Sbjct: 339 PPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP---- 394
Query: 512 NAYPHWQQQAPPDPAKAG 529
P Q Q PP P + G
Sbjct: 395 ---PAGQPQGPPRPPQGG 409
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 78.2 bits (191), Expect = 2e-14
Identities = 92/407 (22%), Positives = 163/407 (40%), Gaps = 60/407 (14%)
Query: 43 AKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQL--PPMHQQQSRSV 100
AKI + + +Y + P E+ P + A + D + P Q+R +
Sbjct: 133 AKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQI 192
Query: 101 -MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQ 158
VP VG IIG+ G I I +++ ++ I ++ G E+ + TPE
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
Query: 159 SAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVK 218
A R++ +I++K +I+ G +IGK G +K+++ G K
Sbjct: 253 EACRMILEIMQKEADETKLAE-----EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTK 307
Query: 219 MVM--IQD----GPQNTGADKPLRITGDPYKVQQAKEMVLELIRD------------QGG 260
+ + +QD P+ T + + G A+ +++ +R+ G
Sbjct: 308 ITISSLQDLSIYNPERT-----ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGY 362
Query: 261 FREV--RNEYGS-----RIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP 313
F + +++G E +++ IP AVG +IG+ G IK++ AG I+ P
Sbjct: 363 FSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAP 422
Query: 314 DDG-TTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGP 372
+G ER+ ITGPP+ A I L+ NP
Sbjct: 423 AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNP--------------------K 462
Query: 373 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPN 419
E + VP+ G +IGKGG+T+ + + A + + R+ P+
Sbjct: 463 EEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
Score = 75.5 bits (184), Expect = 1e-13
Identities = 68/272 (25%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 180 GDGPGNAVQ--------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA 231
G PG Q I++P G +IGK G TIK + ++ + V I + A
Sbjct: 180 GHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAA 238
Query: 232 DKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVI 291
+KP+ I P +A M+LE+++ + ++ E +I + G+ VG +I
Sbjct: 239 EKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGL--------VGRLI 290
Query: 292 GRNGEMIKKIQNDAGVRIQFKPDDGTT---PERIAQITGPPDRCQHAAEIITDLLRSVQA 348
G+ G +KKI+++ G +I + PER + G + C A I LR
Sbjct: 291 GKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE 350
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEF------NFIVPTGKTGLIIGKGGETIKSI 402
+ + GP + N +PT G IIGK G IK +
Sbjct: 351 NDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQL 410
Query: 403 SQQSGARIELQRNPPPNADPNMKLFTIRGTPQ 434
++ +GA I++ P D + ++ I G P+
Sbjct: 411 ARFAGASIKIA--PAEGPDVSERMVIITGPPE 440
Score = 71.2 bits (173), Expect = 3e-12
Identities = 45/152 (29%), Positives = 81/152 (53%), Gaps = 7/152 (4%)
Query: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSG-GLPERSCMLTGTPESVQSAK-RLL 164
+P VG IIG+ G I ++ + +G I+IAP G + ER ++TG PE+ A+ R+
Sbjct: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIF 450
Query: 165 DQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224
++ E+ F + I +P+S AG VIGKGG+T+ +LQ ++++ +D
Sbjct: 451 GKLKEEN-----FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 505
Query: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELIR 256
+ + +RI G + Q A+ + E+++
Sbjct: 506 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQ 537
Score = 69.7 bits (169), Expect = 8e-12
Identities = 75/295 (25%), Positives = 128/295 (43%), Gaps = 55/295 (18%)
Query: 92 MHQQQSRSVMTEEYKVP----DGMVGFIIGRGGEQISRIQQESGCKIQIAPD---SGGLP 144
M ++ + + EE + +G+VG +IG+ G + +I+ E+G KI I+ S P
Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
Query: 145 ERSCMLTGTPESVQSAKRLLDQIVEKGRPA-------------------------PGFHH 179
ER+ + GT E+ SA+ +I++K R A P HH
Sbjct: 322 ERTITVKGTVEACASAEI---EIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHH 378
Query: 180 GDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM-VMIQDGPQNTGADKPLRIT 238
P + + IP G +IGK G IKQL AG + + +GP +++ + IT
Sbjct: 379 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD--VSERMVIIT 436
Query: 239 GDPYKVQQAKEMVLELIRDQGGF---REVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNG 295
G P +A+ + ++++ F EV+ E + +P G VIG+ G
Sbjct: 437 GPPEAQFKAQGRIFGKLKEENFFNPKEEVKLE----------AHIRVPSSTAGRVIGKGG 486
Query: 296 EMIKKIQNDAGVRIQFKPDDGTTPER---IAQITGPPDRCQHAAEIITDLLRSVQ 347
+ + ++QN + P D T E I +I G Q A I ++++ V+
Sbjct: 487 KTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 15/108 (13%)
Query: 347 QAGNPGGPGPGGRG--RGRGQGNWNMGPPGGLQE-------FNFIVPTGKTGLIIGKGGE 397
+ +P P RG R QG+ PGG + +VPT G IIGK G
Sbjct: 159 EVSSPSPPQRAQRGDHSSREQGH----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGL 214
Query: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEE 445
TIK+I++Q+ +R+++ R N+ K TI TP+ A ++I E
Sbjct: 215 TIKNITKQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 75.9 bits (185), Expect = 1e-13
Identities = 90/354 (25%), Positives = 146/354 (41%), Gaps = 49/354 (13%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + RI++ESG +I I+ G PER LTG ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PA++ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 INSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQ-AKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVG 288
++ + I G P V + K++ L ++ E S+ + +P P A
Sbjct: 142 TERAITIAGVPQSVTECVKQICLVML-----------ETLSQSPQGRVMTIPYQPMPASS 190
Query: 289 IVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPP-----DRCQHAAEIITDLL 343
VI G+ + + AG P + GPP + QH + DL
Sbjct: 191 PVICAGGQ--DRCSDAAGY-----------PHATHDLEGPPLDAYSIQGQHTISPL-DLA 236
Query: 344 RSVQAGNP--------GGPGPGG--RGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIG 393
+ Q GG G G +G W +P G IIG
Sbjct: 237 KLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296
Query: 394 KGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
+ G I I Q SGA+I++ P + + TI G+ I A+ LI ++
Sbjct: 297 RQGANINEIRQMSGAQIKIAN---PVEGSSGRQVTITGSAASISLAQYLINARL 347
Score = 47.8 bits (112), Expect = 3e-05
Identities = 70/272 (25%), Positives = 114/272 (41%), Gaps = 39/272 (14%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGV 151
Query: 154 PESV-QSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P+SV + K++ ++E +P G + +PAS VI GG+ +
Sbjct: 152 PQSVTECVKQICLVMLETLSQSP-----QGRVMTIPYQPMPASSP--VICAGGQ--DRCS 202
Query: 213 ERAGVKMVMIQ-DGP-------QNTGADKPLRITGDPYKVQQAKEMVLELIRDQGG---- 260
+ AG +GP Q PL D K+ Q GG
Sbjct: 203 DAAGYPHATHDLEGPPLDAYSIQGQHTISPL----DLAKLNQVARQQSHFAMMHGGTGFA 258
Query: 261 -----FREVRNEYGSRIGGNEGI-DVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KP 313
EV+ + S + ++ IP +G +IGR G I +I+ +G +I+ P
Sbjct: 259 GIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANP 318
Query: 314 DDGTTPERIAQITGPPDRCQHAAEIITDLLRS 345
+G++ ++ ITG A +I L S
Sbjct: 319 VEGSSGRQVT-ITGSAASISLAQYLINARLSS 349
Score = 47.0 bits (110), Expect = 5e-05
Identities = 36/165 (21%), Positives = 77/165 (46%), Gaps = 7/165 (4%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GE++K+++E +G + + I +G ++ + +TG + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKRIREESGAR-INISEG---NCPERIITLTGPTNAIFKAFA 73
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 74 MIIDKLEEDINSSMTNSTAASR--PPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 310 QFKPDD-GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGG 353
Q D + ER I G P + I ++ + +P G
Sbjct: 132 QVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQG 176
Score = 38.1 bits (87), Expect = 0.025
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GE++K I ++SGARI + P ++ T+ G I A +I +K
Sbjct: 24 EVGSIIGKKGESVKRIREESGARINISEGNCPE-----RIITLTGPTNAIFKAFAMIIDK 78
Query: 447 IGGPVN 452
+ +N
Sbjct: 79 LEEDIN 84
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 75.9 bits (185), Expect = 1e-13
Identities = 85/360 (23%), Positives = 149/360 (41%), Gaps = 41/360 (11%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 142 TERAITIAGIPQSIIECVKQICVVMLE---------------SPPKGVTIPYRPKPSSSP 186
Query: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRC-----QHA--AEIITDL 342
VI G+ +D+ P P+ + GPP Q+A +T L
Sbjct: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPD----LEGPPLEAYTIQGQYAIPQPDLTKL 242
Query: 343 --LRSVQAGNP---GGPGPGG--RGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKG 395
L Q+ P G G G +G W + +P G IIG+
Sbjct: 243 HQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQ 302
Query: 396 GETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
G I I Q SGA+I++ + D + TI G+ I A+ LI ++ +G
Sbjct: 303 GAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGGMG 359
Score = 73.2 bits (178), Expect = 7e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
Query: 466 PGP 468
P
Sbjct: 184 SSP 186
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 280 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 339
Query: 157 VQSAKRLLD 165
+ A+ L++
Sbjct: 340 ISLAQYLIN 348
Score = 45.4 bits (106), Expect = 2e-04
Identities = 67/279 (24%), Positives = 106/279 (37%), Gaps = 41/279 (14%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
Query: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P+S ++ K++ ++E P V P + VI GG+
Sbjct: 152 PQSIIECVKQICVVMLE------------SPPKGVTIPYRPKPSSSPVIFAGGQDRYSTG 199
Query: 213 ERAGVKMVMIQDGPQNTGADKP----LRITGDPYKVQQAKEMVLELIRDQGGFREVRNEY 268
+ N + P I G Q + +L Q F
Sbjct: 200 SDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNT 259
Query: 269 G--------SRIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF 311
G + G G+D + IP +G +IGR G I +I+ +G +I+
Sbjct: 260 GFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKI 319
Query: 312 -KPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
P +G+T +R ITG A +I L S G
Sbjct: 320 ANPVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 357
Score = 43.1 bits (100), Expect = 8e-04
Identities = 32/141 (22%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 310 QFKPDD-GTTPERIAQITGPP 329
Q D + ER I G P
Sbjct: 132 QVAGDMLPNSTERAITIAGIP 152
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
Query: 447 I 447
+
Sbjct: 79 L 79
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 74.7 bits (182), Expect = 2e-13
Identities = 56/211 (26%), Positives = 104/211 (49%), Gaps = 32/211 (15%)
Query: 69 DGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQ 122
D D PD++K + PP R+ E+ + +P G IIG+GG+
Sbjct: 19 DLDPPDSRKRP-------LEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQT 71
Query: 123 ISRIQQESGCKIQIAPDSG---GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHH 179
I ++Q+E+G I+++ G ER C++ GT E++ + I EK R P
Sbjct: 72 IVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGF---IAEKIREMPQNVA 128
Query: 180 GDGPGNAVQ-------------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226
P + +Q +I++P S AGL+IGKGG T+K + E++G + + Q
Sbjct: 129 KTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD 188
Query: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRD 257
++ + ++G+P + ++A E++++ I++
Sbjct: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
Score = 73.9 bits (180), Expect = 4e-13
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 18/195 (9%)
Query: 263 EVRNEYGSRIGGNEGID------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD- 315
E E GS N G D V IP +A G +IG+ G+ I ++Q + G I+
Sbjct: 31 EAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
Query: 316 ---GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGP 372
GTT ER+ I G + I + +R + N P + + N
Sbjct: 91 FYPGTT-ERVCLIQGTVEALNAVHGFIAEKIREMPQ-NVAKTEPVSILQPQTTVN----- 143
Query: 373 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGT 432
P +++ IVP GLIIGKGG T+K++ +QSGA ++L + P + ++ T+ G
Sbjct: 144 PDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGE 202
Query: 433 PQQIDYARQLIEEKI 447
P+Q A +LI +KI
Sbjct: 203 PEQNRKAVELIIQKI 217
Score = 47.8 bits (112), Expect = 3e-05
Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGTPESVQSA 160
E VP+ +VG I+G+GG+ + Q+ +G +IQI+ +P R +TGTP + Q+A
Sbjct: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
Query: 161 KRLLDQ 166
+ L+ Q
Sbjct: 461 QYLITQ 466
Score = 45.1 bits (105), Expect = 2e-04
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Query: 187 VQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQ 245
V EI +P + G ++GKGG+T+ + QE G ++ + + G G ++ + ITG P Q
Sbjct: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458
Query: 246 QAKEMVLELIRDQGGFR 262
A+ ++ + I + G R
Sbjct: 459 AAQYLITQRITYEQGVR 475
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/65 (33%), Positives = 34/65 (52%)
Query: 383 VPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQL 442
VP G I+GKGG+T+ + +GARI++ + + TI GTP A+ L
Sbjct: 404 VPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYL 463
Query: 443 IEEKI 447
I ++I
Sbjct: 464 ITQRI 468
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 273 GGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPP 329
G + +++ +P VG ++G+ G+ + + Q G RIQ P R ITG P
Sbjct: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454
Query: 330 DRCQHAAEIITDLL---RSVQAGNP 351
Q A +IT + + V+A NP
Sbjct: 455 AATQAAQYLITQRITYEQGVRAANP 479
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 74.7 bits (182), Expect = 2e-13
Identities = 85/360 (23%), Positives = 149/360 (41%), Gaps = 37/360 (10%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 142 TERAITIAGIPQSIIECVKQICVVMLET-----------LSQSPPKGVTIPYRPKPSSSP 190
Query: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRC-----QHA--AEIITDL 342
VI G+ +D+ P P+ + GPP Q+A +T L
Sbjct: 191 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPD----LEGPPLEAYTIQGQYAIPQPDLTKL 246
Query: 343 --LRSVQAGNP---GGPGPGG--RGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKG 395
L Q+ P G G G +G W + +P G IIG+
Sbjct: 247 HQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQ 306
Query: 396 GETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
G I I Q SGA+I++ + D + TI G+ I A+ LI ++ +G
Sbjct: 307 GAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGGMG 363
Score = 69.7 bits (169), Expect = 8e-12
Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 26/187 (13%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQ----LIEEKIGGPVNPLGPPVPHG 461
GA++++ + PN+ + TI G PQ I+ +Q ++E P P G +P+
Sbjct: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLETLSQSP--PKGVTIPYR 183
Query: 462 PHGVPGP 468
P P
Sbjct: 184 PKPSSSP 190
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 284 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 343
Query: 157 VQSAKRLLD 165
+ A+ L++
Sbjct: 344 ISLAQYLIN 352
Score = 45.8 bits (107), Expect = 1e-04
Identities = 65/278 (23%), Positives = 107/278 (38%), Gaps = 35/278 (12%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
Query: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P+S ++ K++ ++E +P P S + ++ G +
Sbjct: 152 PQSIIECVKQICVVMLETLSQSP-------PKGVTIPYRPKPSSSPVIFAGGQDRYSTGS 204
Query: 213 ERAGVKMV--MIQDGPQNTGADKPLRITGDPYKVQQAKEMVL-ELIRDQGGFREVRNEYG 269
+ A + P G Y + Q L +L Q F G
Sbjct: 205 DSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTG 264
Query: 270 --------SRIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF- 311
+ G G+D + IP +G +IGR G I +I+ +G +I+
Sbjct: 265 FSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 324
Query: 312 KPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
P +G+T +R ITG A +I L S G
Sbjct: 325 NPVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 361
Score = 43.9 bits (102), Expect = 5e-04
Identities = 36/166 (21%), Positives = 77/166 (46%), Gaps = 8/166 (4%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 310 QFKPDD-GTTPERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGG 353
Q D + ER I G P + +I +L ++ P G
Sbjct: 132 QVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
Query: 447 I 447
+
Sbjct: 79 L 79
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 74.7 bits (182), Expect = 2e-13
Identities = 70/292 (23%), Positives = 121/292 (41%), Gaps = 61/292 (20%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLL-----DQ 166
VG IIG+ GE + ++++ESG +I I+ G PER +TG +++ A ++ +
Sbjct: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
Query: 167 IVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226
I+ +P +++PAS+ G +IGKGG IK+++E G ++ + D
Sbjct: 115 IINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDML 170
Query: 227 QNTGADKPLRITGDPYKVQQAKEMV----LELIRDQGGFR-------------------- 262
N+ ++ + I+G P + Q + + LE QG +
Sbjct: 171 PNS-TERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFP 229
Query: 263 ----------------EVRNEYGSRIGGNEGID---------VPIPRFAVGIVIGRNGEM 297
E + +G + G+D + IP +G +IGR G
Sbjct: 230 PLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTK 289
Query: 298 IKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
I +I+ +G +I+ + ER ITG P A +I L S G
Sbjct: 290 INEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTG 341
Score = 72.0 bits (175), Expect = 2e-12
Identities = 63/211 (29%), Positives = 94/211 (44%), Gaps = 40/211 (18%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIIT-----D 341
VG +IG+ GE +KK++ ++G RI +G PERI ITGP D A +I D
Sbjct: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
Query: 342 LLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKS 401
++ S+ + +P PP L+ +VP + G +IGKGG IK
Sbjct: 115 IINSM-SNSPA----------------TSKPPVTLR---LVVPASQCGSLIGKGGSKIKE 154
Query: 402 ISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHG 461
I + +GA++++ + PN+ + TI GTP I + I V L G
Sbjct: 155 IRESTGAQVQVAGDMLPNS--TERAVTISGTPDAIIQCVKQI------CVVMLEAYTIQG 206
Query: 462 PHGVPGP-----HGPPGPPGPGTPMGPYNPA 487
+ +P P H P P+G NPA
Sbjct: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPA 237
Score = 67.0 bits (162), Expect = 5e-11
Identities = 73/306 (23%), Positives = 124/306 (40%), Gaps = 52/306 (16%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GET+K+++E +G + + I +G ++ + ITG + +A
Sbjct: 50 LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEG---NCPERIVTITGPTDAIFKAFA 105
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNE---GIDVPIPRFAVGIVIGRNGEMIKKIQNDAG 306
M+ + ++ N + ++ + + +P G +IG+ G IK+I+ G
Sbjct: 106 MIAYKFEE-----DIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTG 160
Query: 307 VRIQFKPDD-GTTPERIAQITGPPDR--------CQHAAEIIT----------DLLRSVQ 347
++Q D + ER I+G PD C E T DL + Q
Sbjct: 161 AQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQ 220
Query: 348 AG------------NPGGPGPGGRGRGRGQGNWNMGPPGGL------QEFNFIVPTGKTG 389
NP PG + MG GL +P G
Sbjct: 221 LAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIG 280
Query: 390 LIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGG 449
IIG+ G I I Q SGA+I++ +++ + TI GTP I A+ LI ++
Sbjct: 281 CIIGRQGTKINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARLTS 337
Query: 450 PVNPLG 455
V +G
Sbjct: 338 EVTGMG 343
Score = 57.0 bits (136), Expect = 5e-08
Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 11/113 (9%)
Query: 53 LNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMV 112
L + + G+K PL ++ A+ + Q+ P T E +P+ ++
Sbjct: 231 LGQTNPAFPGEKLPLHSSEE--AQNLMGQSSGLDASPP---------ASTHELTIPNDLI 279
Query: 113 GFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLD 165
G IIGR G +I+ I+Q SG +I+IA + G ER +TGTP ++ A+ L++
Sbjct: 280 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332
Score = 48.5 bits (114), Expect = 2e-05
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 63/212 (29%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
S+ +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ ++GT
Sbjct: 126 SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDM--LPNSTERAVTISGT 183
Query: 154 PES-VQSAKRLLDQIVEK------------------------------GRPAPGF----- 177
P++ +Q K++ ++E G+ P F
Sbjct: 184 PDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL 243
Query: 178 --HHGD--------------GPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAG--VKM 219
H + P + E+ IP G +IG+ G I ++++ +G +K+
Sbjct: 244 PLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI 303
Query: 220 VMIQDGPQNTGADKPLRITGDPYKVQQAKEMV 251
+G +++ + ITG P + A+ ++
Sbjct: 304 ANATEG----SSERQITITGTPANISLAQYLI 331
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 74.3 bits (181), Expect = 3e-13
Identities = 65/197 (32%), Positives = 77/197 (39%), Gaps = 43/197 (21%)
Query: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGP-------------GGRGRGRGQGNWNMGPP 373
GPP R AA + D + G PG PGP G RG QG MGP
Sbjct: 1044 GPPGR-DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP--MGPS 1100
Query: 374 GGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTP 433
G P G G+ +G K + + G R + ++G P
Sbjct: 1101 G---------PAGARGIQGPQGPRGDKGEAGEPGER---------GLKGHRGFTGLQGLP 1142
Query: 434 QQIDYARQLIEEKIGGPVNPLGPPVPHGP------HGVPGPHGPPGPPGPGTPMGPYNPA 487
+ GP P GPP P GP +G+PGP GPPGP G GP P
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP- 1201
Query: 488 PYNPGPPGPAPHGPPAP 504
P NPGPPGP GPP P
Sbjct: 1202 PGNPGPPGPP--GPPGP 1216
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/238 (27%), Positives = 79/238 (33%), Gaps = 62/238 (26%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
G G PGP GR G N GPPG P G G
Sbjct: 141 GEKGAPGPRGRDGEPGTPG-NPGPPG---------PPGPPG------------------- 171
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
PP N G ++ A+ + + GP+ P+GP P GP G PGP
Sbjct: 172 --------PPGLGGNFAAQMAGGFDEKAGGAQLGVMQ---GPMGPMGPRGPPGPAGAPGP 220
Query: 469 HG------PPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQA 521
G PG PG PMGP P PGPPG P G G ++
Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGP----PGPPGKPGDDGEAGKPGKAG---------ERG 267
Query: 522 PPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ-GDQQNPAPAG 578
PP P A P + H AGAP +G G+ +P P G
Sbjct: 268 PPGPQGARGFPGTPGLPGVKGH-RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 324
Score = 58.2 bits (139), Expect = 2e-08
Identities = 87/342 (25%), Positives = 107/342 (31%), Gaps = 91/342 (26%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGL------------------ 390
G PG PGP G+ +G + GPPG E P G G
Sbjct: 915 GPPGPPGPSGKDGPKG-ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP 973
Query: 391 --IIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIG 448
+ G+ G I + Q G R P P+ +P + G P
Sbjct: 974 QGLAGQRG--IVGLPGQRGER-GFPGLPGPSGEPGKQ-----GAPGASGDR--------- 1016
Query: 449 GPVNPLGPPVPHGP------HGVPGPHGPPGPPGPGTPMGPYNP-----APYNPGPPG-P 496
GP P+GPP GP G PG GPPG G G AP PGPPG P
Sbjct: 1017 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1076
Query: 497 APHGP------------PAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHY 544
P GP P P G A Q P +P + +
Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG-F 1135
Query: 545 YQQQAQPPPAAPAGAPTTTQTNG-QGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGA 603
Q P P P+G + G G + P P G K +P P G
Sbjct: 1136 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---------KDGANGIPGPIG- 1185
Query: 604 PPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQH--PPAPQG 643
PPG + +T P G P + PP P G
Sbjct: 1186 PPGPR---------------GRSGETGPAGPPGNPGPPGPPG 1212
Score = 57.0 bits (136), Expect = 5e-08
Identities = 88/304 (28%), Positives = 110/304 (36%), Gaps = 49/304 (16%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
GNPG PG G G GPPG P GK G G+ G+ K+ +
Sbjct: 225 GNPGEPGEPGVSGPMGP----RGPPG---------PPGKPG-DDGEAGKPGKAGERGPPG 270
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
+ P P +K RG P +D A+ E G G P G +G PGP
Sbjct: 271 PQGARGFPGTPGLPGVKGH--RGYPG-LDGAKG--EAGAPGVKGESGSP---GENGSPGP 322
Query: 469 HGPPGPPGPGTPMGPYNPAPY--NPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPA 526
GP G PG GP A N G PGPA GPP P P G G +P AP
Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQPGPA--GPPGPVGPAG-GPGFP----GAPGAKG 375
Query: 527 KAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNG----QGDQQNPAPAGQVDY 582
+AG P A + P PAGA T+G +G P AG +
Sbjct: 376 EAG--PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433
Query: 583 TKAWEEYYKKMGQAVPAPTGA--PPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPA 640
+ P P GA P G + ++ + + P G PQ P
Sbjct: 434 PGP---------RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG-PQGAPG 483
Query: 641 PQGQ 644
P G+
Sbjct: 484 PAGE 487
Score = 56.6 bits (135), Expect = 7e-08
Identities = 84/330 (25%), Positives = 100/330 (30%), Gaps = 79/330 (23%)
Query: 349 GNPGGPGPGGRGRGRG-QGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
GNPG PGP G G GN+ GG E K G + Q
Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE---------------KAGGAQLGVMQGPM 203
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
+ + P P P + F +G P + E + GP+ P GPP GP G PG
Sbjct: 204 GPMGPRGPPGPAGAPGPQGF--QGNPGEPG------EPGVSGPMGPRGPP---GPPGKPG 252
Query: 468 PHGPPGPPGPGTPMGPYNPA-----PYNPGPPG--------------------------- 495
G G PG GP P P PG PG
Sbjct: 253 DDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESG 312
Query: 496 -PAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAG-TDPNSAAWAAYYAHYYQQQAQPPP 553
P +G P P P+G P + G T P AA A P P
Sbjct: 313 SPGENGSPGPMGPRGL--------------PGERGRTGPAGAAGARGNDGQPGPAGPPGP 358
Query: 554 AAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSA 613
PAG P G + P A + + G P P GA G P
Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS--PGPAGA--SGNPGTDG 414
Query: 614 AWAEYYRQQAAYYAQTSPQGMPQHPPAPQG 643
A A P+ PP PQG
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Score = 56.2 bits (134), Expect = 9e-08
Identities = 92/344 (26%), Positives = 105/344 (30%), Gaps = 65/344 (18%)
Query: 349 GNPGGPG-PGGRGRGRGQGN----WNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSIS 403
G PG PG PG RG G+ +GP G E P G G +G +
Sbjct: 549 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG---ARGQPGVMGFP 605
Query: 404 QQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPH 463
GA E P A + G P + E GP P GP G
Sbjct: 606 GPKGANGE-----PGKAGEK----GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 656
Query: 464 GVPGPH------GPPGPPGPGTPMGPYNPAPYNPGPPG----------PAPHGPPAPYAP 507
G PGP GPPGPPG G G P G PG P G P
Sbjct: 657 GAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715
Query: 508 QG----------------WGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQP 551
QG G A P Q PP + +A A +
Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPP-GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 774
Query: 552 PPAAPA-----------GAPTTTQTNGQ-GDQQNPAPAGQVDYTKAWEEYYKKMGQAVPA 599
P AP G P NG+ G+ P PAG A E + G PA
Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE-RGETGPPGPA 833
Query: 600 PTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQG 643
PPG A + Q PQG P P PQG
Sbjct: 834 GFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQG 876
Score = 55.5 bits (132), Expect = 2e-07
Identities = 92/351 (26%), Positives = 112/351 (31%), Gaps = 59/351 (16%)
Query: 171 GRPAPGFHHGDG--PGNAVQEIMI-PASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQ 227
G P G GD PG A ++ P + G +G + LQ G+ DGP+
Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 731
Query: 228 NT-------GADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDV 280
GA P + G P ++ + D+G E E G G+
Sbjct: 732 GASGPAGPPGAQGPPGLQGMPG--ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 789
Query: 281 PIPRFAVGIVIGRNGEMIKK-IQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEII 339
PI G GE+ AG R G ER TGPP A
Sbjct: 790 PIGPPGPAGANGEKGEVGPPGPAGSAGAR-------GAPGERGE--TGPPGPAGFAGPPG 840
Query: 340 TDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETI 399
D G PG G G +G G PG P G TG+ KG
Sbjct: 841 AD-------GQPGAKGEQGEAGQKGDA----GAPGPQGPSGAPGPQGPTGVTGPKGARGA 889
Query: 400 KSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVP 459
+ +G R PP ++ N GP P GP
Sbjct: 890 QGPPGATGFPGAAGRVGPPGSNGNP------------------------GPPGPPGPSGK 925
Query: 460 HGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQG 509
GP G G GPPG G GP P P G PG P G P PQG
Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPAGP-PGEKGEPGDDGPSGAEGPPGPQG 975
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/327 (24%), Positives = 101/327 (30%), Gaps = 65/327 (19%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
G PG PGP G G G + G PG + P G+ G +G + + G
Sbjct: 666 GLPGPPGPPGEGGKPG----DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG- 720
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
+ GTP + GP P G P G G+PG
Sbjct: 721 --------------------LPGTPGTDG------PKGASGPAGPPGAQGPPGLQGMPGE 754
Query: 469 HGPPGPPGPGTPMGPYNP-----APYNP---------GPPGPA-------PHGPPAPYAP 507
G G GP G AP GPPGPA GPP P
Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 814
Query: 508 QGWGNAYPHWQQQAPPDPAKAGTDPNS-----AAWAAYYAHYYQQQAQPPPAAPAGAP-- 560
G A + PP PA P + A A P P P+GAP
Sbjct: 815 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874
Query: 561 --TTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDYSAAWAE 617
T T +G + P G + A P P G P P G+ A +
Sbjct: 875 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD 934
Query: 618 YYRQQAAYYAQTSPQGMPQHPPAPQGQ 644
A + QG P PP +G+
Sbjct: 935 SGPPGRA--GEPGLQG-PAGPPGEKGE 958
Score = 52.8 bits (125), Expect = 1e-06
Identities = 74/276 (26%), Positives = 88/276 (31%), Gaps = 85/276 (30%)
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
AG G PGP G RG G PGG+ I P G+ G +G ++ G
Sbjct: 476 AGPQGAPGPAGEEGKRGA----RGEPGGVGP---IGPPGERGAPGNRGFPGQDGLAGPKG 528
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A E R P + GP G P G G+PG
Sbjct: 529 APGE--RGP----------------------------SGLAGPKGANGDPGRPGEPGLPG 558
Query: 468 PHGPPGPPGPGTPMGPYNPA-----PYNPGPPG-------PAPHGPPAPYAPQGW-GNAY 514
G G PG P G P+ PGPPG P G P P G G A
Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618
Query: 515 PHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNP 574
AP G D + A P PA PAG +G+Q P
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGA-----------AGPPGPAGPAGE--------RGEQGAP 659
Query: 575 APAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQP 609
P+G Q +P P G P GG+P
Sbjct: 660 GPSG---------------FQGLPGPPGPPGEGGKP 680
Score = 47.0 bits (110), Expect = 5e-05
Identities = 83/311 (26%), Positives = 101/311 (32%), Gaps = 23/311 (7%)
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+AG G GP G RG+ G PG G G+ KG I+
Sbjct: 376 EAGPTGARGPEGAQGPRGEP----GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVP 466
G P A + G P + + + GP P G P P G G
Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491
Query: 467 GPHGPPGPPGPGTPMGPYNPAPYNPGPPG----PAPHGPPAPYAPQGWGNAYPHWQQQAP 522
G G PG GP P G AP N G PG P G P P G A P P
Sbjct: 492 GARGEPGGVGPIGPPGE-RGAPGNRGFPGQDGLAGPKGAPGERGPSGL--AGPKGANGDP 548
Query: 523 PDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPA-----GAPTTTQTNGQ-GDQQNPAP 576
P + G P + Q P AP G P GQ G P P
Sbjct: 549 GRPGEPGL-PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGP 607
Query: 577 AG-QVDYTKAWEEYYKKMG--QAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQG 633
G + KA E+ + +P G P A A +Q A + QG
Sbjct: 608 KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA-PGPSGFQG 666
Query: 634 MPQHPPAPQGQ 644
+P PP P G+
Sbjct: 667 LP-GPPGPPGE 676
Score = 44.7 bits (104), Expect = 3e-04
Identities = 62/224 (27%), Positives = 68/224 (30%), Gaps = 56/224 (25%)
Query: 449 GPVNPLGPPVPHGPHGVPGPHGPPGPP-------GPGTPMGPYNPA-------------- 487
G P+ P G PGP G G P GP P GP PA
Sbjct: 83 GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 142
Query: 488 ---------PYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAW 537
PG PG P P GPP P P G G + Q A KAG A
Sbjct: 143 KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFA--AQMAGGFDEKAG----GAQL 196
Query: 538 AAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAV 597
+ PP PAGAP QG Q NP G+ + G
Sbjct: 197 GVMQGPMGPMGPRGPP-GPAGAP-----GPQGFQGNPGEPGEPGVS----------GPMG 240
Query: 598 PAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAP 641
P PPG D A +A PQG P P
Sbjct: 241 PRGPPGPPGKPGDDGEAGKP---GKAGERGPPGPQGARGFPGTP 281
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 74.3 bits (181), Expect = 3e-13
Identities = 65/197 (32%), Positives = 77/197 (39%), Gaps = 43/197 (21%)
Query: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGP-------------GGRGRGRGQGNWNMGPP 373
GPP R AA + D + G PG PGP G RG QG MGP
Sbjct: 975 GPPGR-DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP--MGPS 1031
Query: 374 GGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTP 433
G P G G+ +G K + + G R + ++G P
Sbjct: 1032 G---------PAGARGIQGPQGPRGDKGEAGEPGER---------GLKGHRGFTGLQGLP 1073
Query: 434 QQIDYARQLIEEKIGGPVNPLGPPVPHGP------HGVPGPHGPPGPPGPGTPMGPYNPA 487
+ GP P GPP P GP +G+PGP GPPGP G GP P
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP- 1132
Query: 488 PYNPGPPGPAPHGPPAP 504
P NPGPPGP GPP P
Sbjct: 1133 PGNPGPPGPP--GPPGP 1147
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/238 (27%), Positives = 79/238 (33%), Gaps = 62/238 (26%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
G G PGP GR G N GPPG P G G
Sbjct: 72 GEKGAPGPRGRDGEPGTPG-NPGPPG---------PPGPPG------------------- 102
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
PP N G ++ A+ + + GP+ P+GP P GP G PGP
Sbjct: 103 --------PPGLGGNFAAQMAGGFDEKAGGAQLGVMQ---GPMGPMGPRGPPGPAGAPGP 151
Query: 469 HG------PPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQA 521
G PG PG PMGP P PGPPG P G G ++
Sbjct: 152 QGFQGNPGEPGEPGVSGPMGPRGP----PGPPGKPGDDGEAGKPGKAG---------ERG 198
Query: 522 PPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ-GDQQNPAPAG 578
PP P A P + H AGAP +G G+ +P P G
Sbjct: 199 PPGPQGARGFPGTPGLPGVKGH-RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 255
Score = 58.2 bits (139), Expect = 2e-08
Identities = 87/342 (25%), Positives = 107/342 (31%), Gaps = 91/342 (26%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGL------------------ 390
G PG PGP G+ +G + GPPG E P G G
Sbjct: 846 GPPGPPGPSGKDGPKG-ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP 904
Query: 391 --IIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIG 448
+ G+ G I + Q G R P P+ +P + G P
Sbjct: 905 QGLAGQRG--IVGLPGQRGER-GFPGLPGPSGEPGKQ-----GAPGASGDR--------- 947
Query: 449 GPVNPLGPPVPHGP------HGVPGPHGPPGPPGPGTPMGPYNP-----APYNPGPPG-P 496
GP P+GPP GP G PG GPPG G G AP PGPPG P
Sbjct: 948 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1007
Query: 497 APHGP------------PAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHY 544
P GP P P G A Q P +P + +
Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG-F 1066
Query: 545 YQQQAQPPPAAPAGAPTTTQTNG-QGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGA 603
Q P P P+G + G G + P P G K +P P G
Sbjct: 1067 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---------KDGANGIPGPIG- 1116
Query: 604 PPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQH--PPAPQG 643
PPG + +T P G P + PP P G
Sbjct: 1117 PPGPR---------------GRSGETGPAGPPGNPGPPGPPG 1143
Score = 57.0 bits (136), Expect = 5e-08
Identities = 88/304 (28%), Positives = 110/304 (36%), Gaps = 49/304 (16%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
GNPG PG G G GPPG P GK G G+ G+ K+ +
Sbjct: 156 GNPGEPGEPGVSGPMGP----RGPPG---------PPGKPG-DDGEAGKPGKAGERGPPG 201
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
+ P P +K RG P +D A+ E G G P G +G PGP
Sbjct: 202 PQGARGFPGTPGLPGVKGH--RGYPG-LDGAKG--EAGAPGVKGESGSP---GENGSPGP 253
Query: 469 HGPPGPPGPGTPMGPYNPAPY--NPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPA 526
GP G PG GP A N G PGPA GPP P P G G +P AP
Sbjct: 254 MGPRGLPGERGRTGPAGAAGARGNDGQPGPA--GPPGPVGPAG-GPGFP----GAPGAKG 306
Query: 527 KAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNG----QGDQQNPAPAGQVDY 582
+AG P A + P PAGA T+G +G P AG +
Sbjct: 307 EAG--PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364
Query: 583 TKAWEEYYKKMGQAVPAPTGA--PPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPA 640
+ P P GA P G + ++ + + P G PQ P
Sbjct: 365 PGP---------RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG-PQGAPG 414
Query: 641 PQGQ 644
P G+
Sbjct: 415 PAGE 418
Score = 56.6 bits (135), Expect = 7e-08
Identities = 67/233 (28%), Positives = 76/233 (32%), Gaps = 47/233 (20%)
Query: 431 GTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG-------PHGPPGPPGPGTPMGP 483
G PQ + L+ + + P P G G PG P GPPGP GP GP
Sbjct: 5 GAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP 64
Query: 484 YN----------PAPY----NPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKA 528
P P PG PG P P GPP P P G G + Q A KA
Sbjct: 65 RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFA--AQMAGGFDEKA 122
Query: 529 GTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEE 588
G A + PP PAGAP QG Q NP G+ +
Sbjct: 123 G----GAQLGVMQGPMGPMGPRGPP-GPAGAP-----GPQGFQGNPGEPGEPGVS----- 167
Query: 589 YYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAP 641
G P PPG D A +A PQG P P
Sbjct: 168 -----GPMGPRGPPGPPGKPGDDGEAGKP---GKAGERGPPGPQGARGFPGTP 212
Score = 56.2 bits (134), Expect = 9e-08
Identities = 92/344 (26%), Positives = 105/344 (30%), Gaps = 65/344 (18%)
Query: 349 GNPGGPG-PGGRGRGRGQGN----WNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSIS 403
G PG PG PG RG G+ +GP G E P G G +G +
Sbjct: 480 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG---ARGQPGVMGFP 536
Query: 404 QQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPH 463
GA E P A + G P + E GP P GP G
Sbjct: 537 GPKGANGE-----PGKAGEK----GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 587
Query: 464 GVPGPH------GPPGPPGPGTPMGPYNPAPYNPGPPG----------PAPHGPPAPYAP 507
G PGP GPPGPPG G G P G PG P G P
Sbjct: 588 GAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646
Query: 508 QG----------------WGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQP 551
QG G A P Q PP + +A A +
Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPP-GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 705
Query: 552 PPAAPA-----------GAPTTTQTNGQ-GDQQNPAPAGQVDYTKAWEEYYKKMGQAVPA 599
P AP G P NG+ G+ P PAG A E + G PA
Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE-RGETGPPGPA 764
Query: 600 PTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQG 643
PPG A + Q PQG P P PQG
Sbjct: 765 GFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQG 807
Score = 55.5 bits (132), Expect = 2e-07
Identities = 92/351 (26%), Positives = 112/351 (31%), Gaps = 59/351 (16%)
Query: 171 GRPAPGFHHGDG--PGNAVQEIMI-PASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQ 227
G P G GD PG A ++ P + G +G + LQ G+ DGP+
Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 662
Query: 228 NT-------GADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDV 280
GA P + G P ++ + D+G E E G G+
Sbjct: 663 GASGPAGPPGAQGPPGLQGMPG--ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 720
Query: 281 PIPRFAVGIVIGRNGEMIKK-IQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEII 339
PI G GE+ AG R G ER TGPP A
Sbjct: 721 PIGPPGPAGANGEKGEVGPPGPAGSAGAR-------GAPGERGE--TGPPGPAGFAGPPG 771
Query: 340 TDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETI 399
D G PG G G +G G PG P G TG+ KG
Sbjct: 772 AD-------GQPGAKGEQGEAGQKGDA----GAPGPQGPSGAPGPQGPTGVTGPKGARGA 820
Query: 400 KSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVP 459
+ +G R PP ++ N GP P GP
Sbjct: 821 QGPPGATGFPGAAGRVGPPGSNGNP------------------------GPPGPPGPSGK 856
Query: 460 HGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQG 509
GP G G GPPG G GP P P G PG P G P PQG
Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPAGP-PGEKGEPGDDGPSGAEGPPGPQG 906
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/327 (24%), Positives = 101/327 (30%), Gaps = 65/327 (19%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
G PG PGP G G G + G PG + P G+ G +G + + G
Sbjct: 597 GLPGPPGPPGEGGKPG----DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG- 651
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
+ GTP + GP P G P G G+PG
Sbjct: 652 --------------------LPGTPGTDG------PKGASGPAGPPGAQGPPGLQGMPGE 685
Query: 469 HGPPGPPGPGTPMGPYNP-----APYNP---------GPPGPA-------PHGPPAPYAP 507
G G GP G AP GPPGPA GPP P
Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 745
Query: 508 QGWGNAYPHWQQQAPPDPAKAGTDPNS-----AAWAAYYAHYYQQQAQPPPAAPAGAP-- 560
G A + PP PA P + A A P P P+GAP
Sbjct: 746 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805
Query: 561 --TTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDYSAAWAE 617
T T +G + P G + A P P G P P G+ A +
Sbjct: 806 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD 865
Query: 618 YYRQQAAYYAQTSPQGMPQHPPAPQGQ 644
A + QG P PP +G+
Sbjct: 866 SGPPGRA--GEPGLQG-PAGPPGEKGE 889
Score = 52.8 bits (125), Expect = 1e-06
Identities = 74/276 (26%), Positives = 88/276 (31%), Gaps = 85/276 (30%)
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
AG G PGP G RG G PGG+ I P G+ G +G ++ G
Sbjct: 407 AGPQGAPGPAGEEGKRGA----RGEPGGVGP---IGPPGERGAPGNRGFPGQDGLAGPKG 459
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A E R P + GP G P G G+PG
Sbjct: 460 APGE--RGP----------------------------SGLAGPKGANGDPGRPGEPGLPG 489
Query: 468 PHGPPGPPGPGTPMGPYNPA-----PYNPGPPG-------PAPHGPPAPYAPQGW-GNAY 514
G G PG P G P+ PGPPG P G P P G G A
Sbjct: 490 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549
Query: 515 PHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNP 574
AP G D + A P PA PAG +G+Q P
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGA-----------AGPPGPAGPAGE--------RGEQGAP 590
Query: 575 APAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQP 609
P+G Q +P P G P GG+P
Sbjct: 591 GPSG---------------FQGLPGPPGPPGEGGKP 611
Score = 47.0 bits (110), Expect = 5e-05
Identities = 83/311 (26%), Positives = 101/311 (32%), Gaps = 23/311 (7%)
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+AG G GP G RG+ G PG G G+ KG I+
Sbjct: 307 EAGPTGARGPEGAQGPRGEP----GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 362
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVP 466
G P A + G P + + + GP P G P P G G
Sbjct: 363 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422
Query: 467 GPHGPPGPPGPGTPMGPYNPAPYNPGPPG----PAPHGPPAPYAPQGWGNAYPHWQQQAP 522
G G PG GP P G AP N G PG P G P P G A P P
Sbjct: 423 GARGEPGGVGPIGPPGE-RGAPGNRGFPGQDGLAGPKGAPGERGPSGL--AGPKGANGDP 479
Query: 523 PDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPA-----GAPTTTQTNGQ-GDQQNPAP 576
P + G P + Q P AP G P GQ G P P
Sbjct: 480 GRPGEPGL-PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGP 538
Query: 577 AG-QVDYTKAWEEYYKKMG--QAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQG 633
G + KA E+ + +P G P A A +Q A + QG
Sbjct: 539 KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA-PGPSGFQG 597
Query: 634 MPQHPPAPQGQ 644
+P PP P G+
Sbjct: 598 LP-GPPGPPGE 607
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 74.3 bits (181), Expect = 3e-13
Identities = 67/245 (27%), Positives = 101/245 (41%), Gaps = 28/245 (11%)
Query: 274 GNEG---IDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD----GTTPERIAQIT 326
G EG + V IP +A G +IG+ G+ I ++Q + G I+ GTT ER+ +
Sbjct: 28 GEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTT-ERVCLVQ 86
Query: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTG 386
G + I + +R + P + Q N P ++ IVP
Sbjct: 87 GTAEALNAVHSFIAEKVREIPQAMTK---PEVVNILQPQTTMN---PDRAKQAKLIVPNS 140
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
GLIIGKGG T+K++ +QSGA ++L + P + ++ T+ G P+Q+ A I +K
Sbjct: 141 TAGLIIGKGGATVKAVMEQSGAWVQLSQK-PEGINLQERVVTVSGEPEQVHKAVSAIVQK 199
Query: 447 IG-----------GPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG 495
+ N GP P G P+ P P A GP G
Sbjct: 200 VQEDPQSSSCLNISYANVAGPVANSNPTG--SPYASPADVLPAAAAASAAAASGLLGPAG 257
Query: 496 PAPHG 500
A G
Sbjct: 258 LAGVG 262
Score = 72.8 bits (177), Expect = 9e-13
Identities = 53/201 (26%), Positives = 97/201 (48%), Gaps = 25/201 (12%)
Query: 79 APQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQISRIQQESGC 132
AP + + PP RS EE + +P G IIG+GG+ I ++Q+E+G
Sbjct: 5 APDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGA 64
Query: 133 KIQIAPDSG---GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQ- 188
I+++ G ER C++ GT E++ + I EK R P N +Q
Sbjct: 65 TIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSF---IAEKVREIPQAMTKPEVVNILQP 121
Query: 189 ------------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLR 236
++++P S AGL+IGKGG T+K + E++G + + Q ++ +
Sbjct: 122 QTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVT 181
Query: 237 ITGDPYKVQQAKEMVLELIRD 257
++G+P +V +A +++ +++
Sbjct: 182 VSGEPEQVHKAVSAIVQKVQE 202
Score = 49.7 bits (117), Expect = 8e-06
Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 50/157 (31%)
Query: 15 AGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPD 74
AG GGG GGGGG A AA G AG L
Sbjct: 368 AGAGGGAGGGGGPLVA-----------AAAAAGAAGGFLT-------------------- 396
Query: 75 AKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKI 134
A+K+A ++ + E VP+ +VG I+G+GG+ + Q+ +G +I
Sbjct: 397 AEKLAAES----------------AKELVEIAVPENLVGAILGKGGKTLVEYQELTGARI 440
Query: 135 QIAPDSGGLP---ERSCMLTGTPESVQSAKRLLDQIV 168
QI+ LP R +TG+P + Q+A+ L+ Q V
Sbjct: 441 QISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
Score = 43.5 bits (101), Expect = 6e-04
Identities = 22/75 (29%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQQA 247
EI +P + G ++GKGG+T+ + QE G ++ + + G G ++ + ITG P Q A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 248 KEMVLELIRDQGGFR 262
+ ++ + + + G R
Sbjct: 470 QYLISQRVTYEQGVR 484
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Query: 348 AGNPGGPGPGGRGRGRGQGNW----NMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSIS 403
AG GGP G + + + VP G I+GKGG+T+
Sbjct: 374 AGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQ 433
Query: 404 QQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
+ +GARI++ + + TI G+P A+ LI +++
Sbjct: 434 ELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
Score = 37.4 bits (85), Expect = 0.043
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
Query: 276 EGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPPDRC 332
E +++ +P VG ++G+ G+ + + Q G RIQ P R ITG P
Sbjct: 407 ELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAAT 466
Query: 333 QHAAEIITDLL---RSVQAGNP 351
Q A +I+ + + V+A NP
Sbjct: 467 QAAQYLISQRVTYEQGVRASNP 488
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 73.9 bits (180), Expect = 4e-13
Identities = 95/430 (22%), Positives = 173/430 (40%), Gaps = 82/430 (19%)
Query: 63 QKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQ 122
Q+ PL+ QP ++ Q S P +Q + VP VG IIG+ G
Sbjct: 161 QQNPLQ---QPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGAT 217
Query: 123 ISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGD 181
I I +++ KI + ++ G E+S + TPE +A + + +I+ K F
Sbjct: 218 IRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTE-- 275
Query: 182 GPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVM--IQD----GPQNTGADKPL 235
+I+ + G +IGK G +K++++ K+ + +Q+ P+ T +
Sbjct: 276 ---EIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERT-----I 327
Query: 236 RITGDPYKVQQAKEMVLELIRDQ-----------------------GGFREVRNEYGSRI 272
+ G+ +A+E +++ IR+ G F
Sbjct: 328 TVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTS 387
Query: 273 GGNEGIDVPIPRF---------------AVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGT 317
G + P P+F +VG +IG+ G+ IK++ AG I+ P +
Sbjct: 388 GPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAP 447
Query: 318 TPE-RIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGL 376
+ R+ ITGPP+ Q A+ GR G+ + + P +
Sbjct: 448 DAKVRMVIITGPPE-AQFKAQ--------------------GRIYGKIKEENFVSPKEEV 486
Query: 377 Q-EFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQ 435
+ E + VP+ G +IGKGG+T+ + S A + + R+ P+ + + + I G
Sbjct: 487 KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQV-VVKITGHFYA 545
Query: 436 IDYARQLIEE 445
A++ I+E
Sbjct: 546 CQVAQRKIQE 555
Score = 71.6 bits (174), Expect = 2e-12
Identities = 76/316 (24%), Positives = 126/316 (39%), Gaps = 41/316 (12%)
Query: 161 KRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMV 220
+R L Q + +PG P + +++P G +IGK G TI+ + ++ K+
Sbjct: 171 RRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKID 230
Query: 221 MIQDGPQNTGA-DKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGID 279
+ + +N GA +K + I P A + +LE++ + + E +I +
Sbjct: 231 VHRK--ENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNF- 287
Query: 280 VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTT---PERIAQITGPPDRCQHAA 336
VG +IG+ G +KKI+ D +I P T PER + G + C A
Sbjct: 288 -------VGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAE 340
Query: 337 EIITDLLRSVQAGNPGG--------PGPGGRGRG-----RGQGNWNMGPPGGL------- 376
E I +R + PG G G GPP +
Sbjct: 341 EEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQF 400
Query: 377 -----QEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRG 431
+ + +P G IIGK G+ IK +S+ +GA I++ P D +++ I G
Sbjct: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA--PAEAPDAKVRMVIITG 458
Query: 432 TPQQIDYARQLIEEKI 447
P+ A+ I KI
Sbjct: 459 PPEAQFKAQGRIYGKI 474
Score = 71.2 bits (173), Expect = 3e-12
Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 7/185 (3%)
Query: 73 PDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGC 132
P + P + PP Q + T +P VG IIG+ G+ I ++ + +G
Sbjct: 378 PTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGA 437
Query: 133 KIQIAP-DSGGLPERSCMLTGTPESVQSAK-RLLDQIVEKGRPAPGFHHGDGPGNAVQEI 190
I+IAP ++ R ++TG PE+ A+ R+ +I E+ +P I
Sbjct: 438 SIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSP-----KEEVKLEAHI 492
Query: 191 MIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEM 250
+P+ AG VIGKGG+T+ +LQ + ++V+ +D + ++ITG Y Q A+
Sbjct: 493 RVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRK 552
Query: 251 VLELI 255
+ E++
Sbjct: 553 IQEIL 557
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 73.2 bits (178), Expect = 7e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
Query: 466 PGP 468
P
Sbjct: 184 SSP 186
Score = 66.2 bits (160), Expect = 9e-11
Identities = 67/294 (22%), Positives = 121/294 (41%), Gaps = 60/294 (20%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQ----------------------GGFREVRNEY 268
++ + I G P + + + + ++ + G ++ +Y
Sbjct: 142 TERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQY 201
Query: 269 G-----------------------SRIGGNEGID---------VPIPRFAVGIVIGRNGE 296
G + G+D + IP +G +IGR G
Sbjct: 202 AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGA 261
Query: 297 MIKKIQNDAGVRIQF-KPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
I +I+ +G +I+ P +G+T +R ITG A +I L S G
Sbjct: 262 KINEIRQMSGAQIKIANPVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 314
Score = 54.7 bits (130), Expect = 3e-07
Identities = 68/308 (22%), Positives = 124/308 (40%), Gaps = 51/308 (16%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 310 QFKPDD-GTTPERIAQITG-PPDRCQHAAEIITDLLRSVQAG--NPGGPGP-------GG 358
Q D + ER I G P + +I +L S G P P P G
Sbjct: 132 QVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAG 191
Query: 359 RGRGRGQGNWNMGPPG-------GLQEFNFIVPTGKTGL--------------------- 390
QG + + P +Q+ +F + G TG
Sbjct: 192 GQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDL 251
Query: 391 ---IIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
IIG+ G I I Q SGA+I++ + D + TI G+ I A+ LI ++
Sbjct: 252 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 308
Query: 448 GGPVNPLG 455
+G
Sbjct: 309 SSETGGMG 316
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 237 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 296
Query: 157 VQSAKRLLD 165
+ A+ L++
Sbjct: 297 ISLAQYLIN 305
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/225 (22%), Positives = 91/225 (40%), Gaps = 65/225 (28%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
Query: 154 PES-VQSAKRLLDQIVE---KG-----RPAPG---------------------------- 176
P+S ++ K++ ++E KG RP P
Sbjct: 152 PQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKL 211
Query: 177 -----------FHHGDGPGNA---------VQEIMIPASKAGLVIGKGGETIKQLQERAG 216
HG+ +A E+ IP G +IG+ G I ++++ +G
Sbjct: 212 HQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSG 271
Query: 217 VKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMV-LELIRDQGG 260
++ + P D+ + ITG + A+ ++ + L + GG
Sbjct: 272 AQIKIA--NPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGG 314
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 73.2 bits (178), Expect = 7e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
Query: 466 PGP 468
P
Sbjct: 184 SSP 186
Score = 71.6 bits (174), Expect = 2e-12
Identities = 84/362 (23%), Positives = 146/362 (40%), Gaps = 44/362 (12%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 142 TERAITIAGIPQSIIECVKQICVVMLE---------------SPPKGVTIPYRPKPSSSP 186
Query: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRC-----QHAAEIITDLLR 344
VI G+ +D+ P P+ + GPP Q+A DL +
Sbjct: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPD----LEGPPLEAYTIQGQYAIP-QPDLTK 241
Query: 345 SVQAGNPGGPGPGGRGRGRGQGNWNMGPP-----GGLQ------EFNFIVPTGKTGLIIG 393
Q P G G + P GL +P G IIG
Sbjct: 242 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIG 301
Query: 394 KGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNP 453
+ G I I Q SGA+I++ + D + TI G+ I A+ LI ++
Sbjct: 302 RQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGG 358
Query: 454 LG 455
+G
Sbjct: 359 MG 360
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 281 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 340
Query: 157 VQSAKRLLD 165
+ A+ L++
Sbjct: 341 ISLAQYLIN 349
Score = 43.9 bits (102), Expect = 5e-04
Identities = 61/277 (22%), Positives = 105/277 (37%), Gaps = 36/277 (12%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
Query: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P+S ++ K++ ++E P G P + ++ + G +
Sbjct: 152 PQSIIECVKQICVVMLES--PPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTT 209
Query: 213 ERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQ----------AKEMVLELIRDQGGFR 262
+ P G Y + Q ++ + GF
Sbjct: 210 PSMCL-------NPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS 262
Query: 263 EVRNEYGSRIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-K 312
+ + G G+D + IP +G +IGR G I +I+ +G +I+
Sbjct: 263 GIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 322
Query: 313 PDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
P +G+T +R ITG A +I L S G
Sbjct: 323 PVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 358
Score = 43.1 bits (100), Expect = 8e-04
Identities = 32/141 (22%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 310 QFKPDD-GTTPERIAQITGPP 329
Q D + ER I G P
Sbjct: 132 QVAGDMLPNSTERAITIAGIP 152
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
Query: 447 I 447
+
Sbjct: 79 L 79
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 73.2 bits (178), Expect = 7e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
Query: 466 PGP 468
P
Sbjct: 184 SSP 186
Score = 68.9 bits (167), Expect = 1e-11
Identities = 79/347 (22%), Positives = 141/347 (40%), Gaps = 45/347 (12%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 142 TERAITIAGIPQSIIECVKQICVVMLE---------------SPPKGVTIPYRPKPSSSP 186
Query: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
VI G+ IQ + +PD + Q + P + G
Sbjct: 187 VIFAGGQAY-TIQGQYAIP---QPDLTKLHQLAMQQSHFP----------------MTHG 226
Query: 350 NPGGPGPGGRGRGRGQGNW-NMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
N G G +G W + +P G IIG+ G I I Q SGA
Sbjct: 227 NTGFSGIES-SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGA 285
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
+I++ + D + TI G+ I A+ LI ++ +G
Sbjct: 286 QIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGGMG 329
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 250 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 309
Query: 157 VQSAKRLLD 165
+ A+ L++
Sbjct: 310 ISLAQYLIN 318
Score = 47.4 bits (111), Expect = 4e-05
Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 51/269 (18%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
Query: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P+S ++ K++ ++E P V P + VI GG+ +Q
Sbjct: 152 PQSIIECVKQICVVMLE------------SPPKGVTIPYRPKPSSSPVIFAGGQAY-TIQ 198
Query: 213 ERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQ--AKEMVLELIRDQGGFREVRNEYGS 270
+ + PQ D K+ Q ++ + GF + +
Sbjct: 199 GQYAI--------PQ-----------PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPE 239
Query: 271 RIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGTTPE 320
G G+D + IP +G +IGR G I +I+ +G +I+ P +G+T +
Sbjct: 240 VKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST-D 298
Query: 321 RIAQITGPPDRCQHAAEIITDLLRSVQAG 349
R ITG A +I L S G
Sbjct: 299 RQVTITGSAASISLAQYLINVRLSSETGG 327
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
Query: 447 I 447
+
Sbjct: 79 L 79
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 73.2 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRL 163
E +VP V IIGR G I ++++++G +I + + G ER +++G P V AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
Query: 164 LDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQ 223
+ QI+ + P +++ +P G +IG+GGETI+ + + +G K+ +
Sbjct: 115 IHQILTENTPVS------------EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 224 DGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFRE 263
+ + ++I+G +V AK ++LE + + R+
Sbjct: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRK 202
Score = 63.2 bits (152), Expect = 7e-10
Identities = 54/189 (28%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 261 FREVRNEYGSRIGGNE-GIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319
+RE R E + +G ++ I++ +P+ AV ++IGR G IK+++ G RI +D
Sbjct: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGD 95
Query: 320 ERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQE 378
ER+ I+G P C+ A I L +
Sbjct: 96 ERVLLISGFPVQVCKAKAAIHQILTENTPVSE---------------------------- 127
Query: 379 FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDY 438
VP G IIG+GGETI+SI + SGA+I + + +L I GT +++
Sbjct: 128 -QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLS-RLIKISGTQKEVAA 185
Query: 439 ARQLIEEKI 447
A+ LI EK+
Sbjct: 186 AKHLILEKV 194
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 20/155 (12%)
Query: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAK 248
E+ +P L+IG+ G IKQL+++ G + I ++ G ++ L I+G P +V +AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 249 EMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVR 308
+ +++ + E + +P+ +VG +IGR GE I+ I +G +
Sbjct: 113 AAIHQILTENTPVSE---------------QLSVPQRSVGRIIGRGGETIRSICKASGAK 157
Query: 309 IQF-KPDDGT-TPERIAQITGPPDRCQHAAEIITD 341
I K +GT R+ +I+G A +I +
Sbjct: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE 192
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 101 MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGG--LPERSCMLTGTPESVQ 158
++E+ VP VG IIGRGGE I I + SG KI +S G L R ++GT + V
Sbjct: 125 VSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVA 184
Query: 159 SAKRLL 164
+AK L+
Sbjct: 185 AAKHLI 190
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 73.2 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRL 163
E +VP V IIGR G I ++++++G +I + + G ER +++G P V AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
Query: 164 LDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQ 223
+ QI+ + P +++ +P G +IG+GGETI+ + + +G K+ +
Sbjct: 115 IHQILTENTPVS------------EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 224 DGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFRE 263
+ + ++I+G +V AK ++LE + + R+
Sbjct: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRK 202
Score = 63.2 bits (152), Expect = 7e-10
Identities = 54/189 (28%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 261 FREVRNEYGSRIGGNE-GIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319
+RE R E + +G ++ I++ +P+ AV ++IGR G IK+++ G RI +D
Sbjct: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGD 95
Query: 320 ERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQE 378
ER+ I+G P C+ A I L +
Sbjct: 96 ERVLLISGFPVQVCKAKAAIHQILTENTPVSE---------------------------- 127
Query: 379 FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDY 438
VP G IIG+GGETI+SI + SGA+I + + +L I GT +++
Sbjct: 128 -QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLS-RLIKISGTQKEVAA 185
Query: 439 ARQLIEEKI 447
A+ LI EK+
Sbjct: 186 AKHLILEKV 194
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 20/155 (12%)
Query: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAK 248
E+ +P L+IG+ G IKQL+++ G + I ++ G ++ L I+G P +V +AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 249 EMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVR 308
+ +++ + E + +P+ +VG +IGR GE I+ I +G +
Sbjct: 113 AAIHQILTENTPVSE---------------QLSVPQRSVGRIIGRGGETIRSICKASGAK 157
Query: 309 IQF-KPDDGT-TPERIAQITGPPDRCQHAAEIITD 341
I K +GT R+ +I+G A +I +
Sbjct: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE 192
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 101 MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGG--LPERSCMLTGTPESVQ 158
++E+ VP VG IIGRGGE I I + SG KI +S G L R ++GT + V
Sbjct: 125 VSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVA 184
Query: 159 SAKRLL 164
+AK L+
Sbjct: 185 AAKHLI 190
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 73.2 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRL 163
E +VP V IIGR G I ++++++G +I + + G ER +++G P V AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
Query: 164 LDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQ 223
+ QI+ + P +++ +P G +IG+GGETI+ + + +G K+ +
Sbjct: 115 IHQILTENTPVS------------EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 224 DGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFRE 263
+ + ++I+G +V AK ++LE + + R+
Sbjct: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRK 202
Score = 63.2 bits (152), Expect = 7e-10
Identities = 54/189 (28%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 261 FREVRNEYGSRIGGNE-GIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319
+RE R E + +G ++ I++ +P+ AV ++IGR G IK+++ G RI +D
Sbjct: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGD 95
Query: 320 ERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQE 378
ER+ I+G P C+ A I L +
Sbjct: 96 ERVLLISGFPVQVCKAKAAIHQILTENTPVSE---------------------------- 127
Query: 379 FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDY 438
VP G IIG+GGETI+SI + SGA+I + + +L I GT +++
Sbjct: 128 -QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLS-RLIKISGTQKEVAA 185
Query: 439 ARQLIEEKI 447
A+ LI EK+
Sbjct: 186 AKHLILEKV 194
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 20/155 (12%)
Query: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAK 248
E+ +P L+IG+ G IKQL+++ G + I ++ G ++ L I+G P +V +AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 249 EMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVR 308
+ +++ + E + +P+ +VG +IGR GE I+ I +G +
Sbjct: 113 AAIHQILTENTPVSE---------------QLSVPQRSVGRIIGRGGETIRSICKASGAK 157
Query: 309 IQF-KPDDGT-TPERIAQITGPPDRCQHAAEIITD 341
I K +GT R+ +I+G A +I +
Sbjct: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE 192
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 101 MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGG--LPERSCMLTGTPESVQ 158
++E+ VP VG IIGRGGE I I + SG KI +S G L R ++GT + V
Sbjct: 125 VSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVA 184
Query: 159 SAKRLL 164
+AK L+
Sbjct: 185 AAKHLI 190
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 72.0 bits (175), Expect = 2e-12
Identities = 64/207 (30%), Positives = 81/207 (39%), Gaps = 41/207 (19%)
Query: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTG 386
GPP + + + + R G PG GP G +G+ +GPPG +F F
Sbjct: 1264 GPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE----VGPPGPPGQFPFDFLQL 1319
Query: 387 KTGLIIGKGGETIKSISQQSGARIE----------LQRNPPPNAD------PNMKLFTIR 430
+ + KG + + + Q G R E L P P P K +IR
Sbjct: 1320 EAEM---KGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIR 1376
Query: 431 GTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYN 490
G P GP P GPP G G GP GPPGPPGP + GP+
Sbjct: 1377 GQP---------------GPPGPQGPP-GIGYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1420
Query: 491 PGPPGPAPHGPPAPYAPQGWGNAYPHW 517
PGPPGP GPP P G + W
Sbjct: 1421 PGPPGPP--GPPGPPGTMGASSGVRLW 1445
Score = 62.8 bits (151), Expect = 1e-09
Identities = 83/313 (26%), Positives = 107/313 (34%), Gaps = 76/313 (24%)
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
AG PG GP G +G+ G PG E G+ G I G + + +
Sbjct: 1150 AGFPGPAGPKGNLGSKGE----RGSPGPKGE------KGEPGSIFSPDGGALGPAQKGAK 1199
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPP----VPHGPH 463
+ P P P K +I + + + G G P + G
Sbjct: 1200 GEPGFRGPPGPYGRPGYK--------GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMR 1251
Query: 464 GVPGPHGPPGPPG-PGTPMGPYN--PAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQ 519
G+PGP GPPGPPG PGTP+ N PGPPG P GPP P +G +
Sbjct: 1252 GMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG---------E 1302
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ-GDQQNPAPAG 578
PP P + + Q +A+ G GQ G++ P G
Sbjct: 1303 VGPPGPP-----------GQFPFDFLQLEAE-----MKGEKGDRGDAGQKGERGEPGGGG 1346
Query: 579 QVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDYSAAWAEYYRQQAAYYAQTSPQGMP-- 635
G ++P P G P P G P E R Q PQG P
Sbjct: 1347 -------------FFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQP---GPPGPQGPPGI 1390
Query: 636 -----QHPPAPQG 643
Q PP P G
Sbjct: 1391 GYEGRQGPPGPPG 1403
Score = 56.6 bits (135), Expect = 7e-08
Identities = 86/327 (26%), Positives = 104/327 (31%), Gaps = 98/327 (29%)
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Q G PG PGP GR G GPPG +P + L G G ++++
Sbjct: 756 QKGEPGVPGPPGRA-GPPGSPCLPGPPG--------LPCPVSPL--GPAGPALQTVPGPQ 804
Query: 407 GARIELQRNPPPNAD------------PNMKLFTIRGTPQQIDYARQLIEEKIG--GPVN 452
G R+ P D + GTP + + +G GP
Sbjct: 805 GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPG 864
Query: 453 PLGPPVP---------------------------HGPHGVPGPHGPPGPPG-PGTP---- 480
P GPP P GP G PGP GPPG PG PG P
Sbjct: 865 PQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG 924
Query: 481 ------MGPYN--PAPYNPGPPG----PAPHGPPAPYAPQ---------GWGNAYPHWQQ 519
GP P GPPG P P GPP P G A H
Sbjct: 925 VNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 984
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQ 579
+ P PA A + A P PA P G P G G PAG
Sbjct: 985 KGAPGPAGARGESGLA-------------GAPGPAGPPGPPGPPGPPGPG-----LPAGF 1026
Query: 580 VDYTKAWEEYYKKMGQAVPAPTGAPPG 606
D + ++ ++ P G PPG
Sbjct: 1027 DDMEGSGGPFW-STARSADGPQG-PPG 1051
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/204 (28%), Positives = 74/204 (36%), Gaps = 44/204 (21%)
Query: 448 GGPVNPLGPPVPHGPHGVPGPHGPPGPPG-PGTPMGPYNPAPYNP-GPPGPAPHGPPAPY 505
GG V G G GVPGP G GPPG P P P P P +P GP GPA P P
Sbjct: 745 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQ 804
Query: 506 APQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQT 565
P G P + P + G DP + +P P G P T
Sbjct: 805 GPPG-----PPGRDGTPGRDGEPG-DPG-------------EDGKPGDTGPQGFPGTPGD 845
Query: 566 NG-QGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAA 624
G +GD+ +P G+ + P P G P P + + + +
Sbjct: 846 VGPKGDKGDPG-VGE---------------RGPPGPQGPPGPPGPSFRHDKLTFIDMEGS 889
Query: 625 YY-----AQTSPQGMPQHPPAPQG 643
+ A P+G P PP P G
Sbjct: 890 GFGGDLEALRGPRGFP-GPPGPPG 912
Score = 48.1 bits (113), Expect = 2e-05
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 74/329 (22%)
Query: 349 GNPGGPGPGGRGRGRGQGNWN-MGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
G PG PGP G G G + G P + P G GL KG + + G
Sbjct: 1010 GPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLP---G 1066
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A+ E+ + P G P + E I GP P G G G PG
Sbjct: 1067 AKGEVGADGVPG---------FPGLPGR---------EGIAGPQGPKGDRGSRGEKGDPG 1108
Query: 468 PH--------GPPGPPGPGTPMGPYNPAPYN-PGPPG-PAPHGPPAPYAPQG-------W 510
GPPGPPGP + + + + PGP G P G P P P+G
Sbjct: 1109 KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGER 1168
Query: 511 GNAYPHWQQQAP-----PD-----PAKAGT--DPNSAAWAAYYAHYYQQQAQPPPAAPAG 558
G+ P ++ P PD PA+ G +P Y + P P G
Sbjct: 1169 GSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRP-G 1227
Query: 559 APTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDY-SAAWA 616
P G+ + A G + + P P G P P G P Y S +A
Sbjct: 1228 RPGMNGLKGEKGEPGDASLG----------FGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1277
Query: 617 EYYRQQAAYYAQTSPQGMP--QHPPAPQG 643
E R P G+P Q PP P+G
Sbjct: 1278 ESSR--------PGPPGLPGNQGPPGPKG 1298
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/318 (25%), Positives = 98/318 (30%), Gaps = 66/318 (20%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG- 407
G PG PGP GR GPPG + + G G KG +SG
Sbjct: 950 GLPGPPGPPGRE----------GPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGL 999
Query: 408 ARIELQRNPP----PNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPV--NPLGPPVPHG 461
A PP P P G P D E GGP P G
Sbjct: 1000 AGAPGPAGPPGPPGPPGPPGP------GLPAGFDDM-----EGSGGPFWSTARSADGPQG 1048
Query: 462 PHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQ 520
P G+PG G PG PG G A PG PG P G P P+G +
Sbjct: 1049 PPGLPGLKGDPGVPGLPGAKGEVG-ADGVPGFPGLPGREGIAGPQGPKG-----DRGSRG 1102
Query: 521 APPDPAKAGTD----PNSAAWAAYYAHYYQQQAQ----------------PPPAAPAGAP 560
DP K G P + +Q P PA P G
Sbjct: 1103 EKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG-- 1160
Query: 561 TTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYR 620
+G++ +P P G+ + + G PA GA G+P + Y R
Sbjct: 1161 ---NLGSKGERGSPGPKGEKG--EPGSIFSPDGGALGPAQKGAK--GEPGFRGPPGPYGR 1213
Query: 621 QQAAYYAQTSPQGMPQHP 638
Y + G P P
Sbjct: 1214 --PGYKGEIGFPGRPGRP 1229
>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
sapiens]
Length = 1336
Score = 72.0 bits (175), Expect = 2e-12
Identities = 64/207 (30%), Positives = 81/207 (39%), Gaps = 41/207 (19%)
Query: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTG 386
GPP + + + + R G PG GP G +G+ +GPPG +F F
Sbjct: 849 GPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE----VGPPGPPGQFPFDFLQL 904
Query: 387 KTGLIIGKGGETIKSISQQSGARIE----------LQRNPPPNAD------PNMKLFTIR 430
+ + KG + + + Q G R E L P P P K +IR
Sbjct: 905 EAEM---KGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIR 961
Query: 431 GTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYN 490
G P GP P GPP G G GP GPPGPPGP + GP+
Sbjct: 962 GQP---------------GPPGPQGPP-GIGYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005
Query: 491 PGPPGPAPHGPPAPYAPQGWGNAYPHW 517
PGPPGP GPP P G + W
Sbjct: 1006 PGPPGPP--GPPGPPGTMGASSGVRLW 1030
Score = 62.8 bits (151), Expect = 1e-09
Identities = 83/313 (26%), Positives = 107/313 (34%), Gaps = 76/313 (24%)
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
AG PG GP G +G+ G PG E G+ G I G + + +
Sbjct: 735 AGFPGPAGPKGNLGSKGE----RGSPGPKGE------KGEPGSIFSPDGGALGPAQKGAK 784
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPP----VPHGPH 463
+ P P P K +I + + + G G P + G
Sbjct: 785 GEPGFRGPPGPYGRPGYK--------GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMR 836
Query: 464 GVPGPHGPPGPPG-PGTPMGPYN--PAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQ 519
G+PGP GPPGPPG PGTP+ N PGPPG P GPP P +G +
Sbjct: 837 GMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG---------E 887
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ-GDQQNPAPAG 578
PP P + + Q +A+ G GQ G++ P G
Sbjct: 888 VGPPGPP-----------GQFPFDFLQLEAE-----MKGEKGDRGDAGQKGERGEPGGGG 931
Query: 579 QVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDYSAAWAEYYRQQAAYYAQTSPQGMP-- 635
G ++P P G P P G P E R Q PQG P
Sbjct: 932 -------------FFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQP---GPPGPQGPPGI 975
Query: 636 -----QHPPAPQG 643
Q PP P G
Sbjct: 976 GYEGRQGPPGPPG 988
Score = 56.6 bits (135), Expect = 7e-08
Identities = 86/327 (26%), Positives = 104/327 (31%), Gaps = 98/327 (29%)
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Q G PG PGP GR G GPPG +P + L G G ++++
Sbjct: 341 QKGEPGVPGPPGRA-GPPGSPCLPGPPG--------LPCPVSPL--GPAGPALQTVPGPQ 389
Query: 407 GARIELQRNPPPNAD------------PNMKLFTIRGTPQQIDYARQLIEEKIG--GPVN 452
G R+ P D + GTP + + +G GP
Sbjct: 390 GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPG 449
Query: 453 PLGPPVP---------------------------HGPHGVPGPHGPPGPPG-PGTP---- 480
P GPP P GP G PGP GPPG PG PG P
Sbjct: 450 PQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG 509
Query: 481 ------MGPYN--PAPYNPGPPG----PAPHGPPAPYAPQ---------GWGNAYPHWQQ 519
GP P GPPG P P GPP P G A H
Sbjct: 510 VNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 569
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQ 579
+ P PA A + A P PA P G P G G PAG
Sbjct: 570 KGAPGPAGARGESGLA-------------GAPGPAGPPGPPGPPGPPGPG-----LPAGF 611
Query: 580 VDYTKAWEEYYKKMGQAVPAPTGAPPG 606
D + ++ ++ P G PPG
Sbjct: 612 DDMEGSGGPFW-STARSADGPQG-PPG 636
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/204 (28%), Positives = 74/204 (36%), Gaps = 44/204 (21%)
Query: 448 GGPVNPLGPPVPHGPHGVPGPHGPPGPPG-PGTPMGPYNPAPYNP-GPPGPAPHGPPAPY 505
GG V G G GVPGP G GPPG P P P P P +P GP GPA P P
Sbjct: 330 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQ 389
Query: 506 APQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQT 565
P G P + P + G DP + +P P G P T
Sbjct: 390 GPPG-----PPGRDGTPGRDGEPG-DPG-------------EDGKPGDTGPQGFPGTPGD 430
Query: 566 NG-QGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAA 624
G +GD+ +P G+ + P P G P P + + + +
Sbjct: 431 VGPKGDKGDPG-VGE---------------RGPPGPQGPPGPPGPSFRHDKLTFIDMEGS 474
Query: 625 YY-----AQTSPQGMPQHPPAPQG 643
+ A P+G P PP P G
Sbjct: 475 GFGGDLEALRGPRGFP-GPPGPPG 497
Score = 48.1 bits (113), Expect = 2e-05
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 74/329 (22%)
Query: 349 GNPGGPGPGGRGRGRGQGNWN-MGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
G PG PGP G G G + G P + P G GL KG + + G
Sbjct: 595 GPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLP---G 651
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A+ E+ + P G P + E I GP P G G G PG
Sbjct: 652 AKGEVGADGVPG---------FPGLPGR---------EGIAGPQGPKGDRGSRGEKGDPG 693
Query: 468 PH--------GPPGPPGPGTPMGPYNPAPYN-PGPPG-PAPHGPPAPYAPQG-------W 510
GPPGPPGP + + + + PGP G P G P P P+G
Sbjct: 694 KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGER 753
Query: 511 GNAYPHWQQQAP-----PD-----PAKAGT--DPNSAAWAAYYAHYYQQQAQPPPAAPAG 558
G+ P ++ P PD PA+ G +P Y + P P G
Sbjct: 754 GSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRP-G 812
Query: 559 APTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDY-SAAWA 616
P G+ + A G + + P P G P P G P Y S +A
Sbjct: 813 RPGMNGLKGEKGEPGDASLG----------FGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862
Query: 617 EYYRQQAAYYAQTSPQGMP--QHPPAPQG 643
E R P G+P Q PP P+G
Sbjct: 863 ESSR--------PGPPGLPGNQGPPGPKG 883
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/318 (25%), Positives = 98/318 (30%), Gaps = 66/318 (20%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG- 407
G PG PGP GR GPPG + + G G KG +SG
Sbjct: 535 GLPGPPGPPGRE----------GPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGL 584
Query: 408 ARIELQRNPP----PNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPV--NPLGPPVPHG 461
A PP P P G P D E GGP P G
Sbjct: 585 AGAPGPAGPPGPPGPPGPPGP------GLPAGFDDM-----EGSGGPFWSTARSADGPQG 633
Query: 462 PHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQ 520
P G+PG G PG PG G A PG PG P G P P+G +
Sbjct: 634 PPGLPGLKGDPGVPGLPGAKGEVG-ADGVPGFPGLPGREGIAGPQGPKG-----DRGSRG 687
Query: 521 APPDPAKAGTD----PNSAAWAAYYAHYYQQQAQ----------------PPPAAPAGAP 560
DP K G P + +Q P PA P G
Sbjct: 688 EKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG-- 745
Query: 561 TTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYR 620
+G++ +P P G+ + + G PA GA G+P + Y R
Sbjct: 746 ---NLGSKGERGSPGPKGEKG--EPGSIFSPDGGALGPAQKGAK--GEPGFRGPPGPYGR 798
Query: 621 QQAAYYAQTSPQGMPQHP 638
Y + G P P
Sbjct: 799 --PGYKGEIGFPGRPGRP 814
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 72.0 bits (175), Expect = 2e-12
Identities = 64/207 (30%), Positives = 81/207 (39%), Gaps = 41/207 (19%)
Query: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTG 386
GPP + + + + R G PG GP G +G+ +GPPG +F F
Sbjct: 1029 GPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE----VGPPGPPGQFPFDFLQL 1084
Query: 387 KTGLIIGKGGETIKSISQQSGARIE----------LQRNPPPNAD------PNMKLFTIR 430
+ + KG + + + Q G R E L P P P K +IR
Sbjct: 1085 EAEM---KGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIR 1141
Query: 431 GTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYN 490
G P GP P GPP G G GP GPPGPPGP + GP+
Sbjct: 1142 GQP---------------GPPGPQGPP-GIGYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1185
Query: 491 PGPPGPAPHGPPAPYAPQGWGNAYPHW 517
PGPPGP GPP P G + W
Sbjct: 1186 PGPPGPP--GPPGPPGTMGASSGVRLW 1210
Score = 62.8 bits (151), Expect = 1e-09
Identities = 83/313 (26%), Positives = 107/313 (34%), Gaps = 76/313 (24%)
Query: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
AG PG GP G +G+ G PG E G+ G I G + + +
Sbjct: 915 AGFPGPAGPKGNLGSKGE----RGSPGPKGE------KGEPGSIFSPDGGALGPAQKGAK 964
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPP----VPHGPH 463
+ P P P K +I + + + G G P + G
Sbjct: 965 GEPGFRGPPGPYGRPGYK--------GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMR 1016
Query: 464 GVPGPHGPPGPPG-PGTPMGPYN--PAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQ 519
G+PGP GPPGPPG PGTP+ N PGPPG P GPP P +G +
Sbjct: 1017 GMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG---------E 1067
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ-GDQQNPAPAG 578
PP P + + Q +A+ G GQ G++ P G
Sbjct: 1068 VGPPGPP-----------GQFPFDFLQLEAE-----MKGEKGDRGDAGQKGERGEPGGGG 1111
Query: 579 QVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDYSAAWAEYYRQQAAYYAQTSPQGMP-- 635
G ++P P G P P G P E R Q PQG P
Sbjct: 1112 -------------FFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQP---GPPGPQGPPGI 1155
Query: 636 -----QHPPAPQG 643
Q PP P G
Sbjct: 1156 GYEGRQGPPGPPG 1168
Score = 56.6 bits (135), Expect = 7e-08
Identities = 86/327 (26%), Positives = 104/327 (31%), Gaps = 98/327 (29%)
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Q G PG PGP GR G GPPG +P + L G G ++++
Sbjct: 521 QKGEPGVPGPPGRA-GPPGSPCLPGPPG--------LPCPVSPL--GPAGPALQTVPGPQ 569
Query: 407 GARIELQRNPPPNAD------------PNMKLFTIRGTPQQIDYARQLIEEKIG--GPVN 452
G R+ P D + GTP + + +G GP
Sbjct: 570 GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPG 629
Query: 453 PLGPPVP---------------------------HGPHGVPGPHGPPGPPG-PGTP---- 480
P GPP P GP G PGP GPPG PG PG P
Sbjct: 630 PQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG 689
Query: 481 ------MGPYN--PAPYNPGPPG----PAPHGPPAPYAPQ---------GWGNAYPHWQQ 519
GP P GPPG P P GPP P G A H
Sbjct: 690 VNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 749
Query: 520 QAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQ 579
+ P PA A + A P PA P G P G G PAG
Sbjct: 750 KGAPGPAGARGESGLA-------------GAPGPAGPPGPPGPPGPPGPG-----LPAGF 791
Query: 580 VDYTKAWEEYYKKMGQAVPAPTGAPPG 606
D + ++ ++ P G PPG
Sbjct: 792 DDMEGSGGPFW-STARSADGPQG-PPG 816
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/204 (28%), Positives = 74/204 (36%), Gaps = 44/204 (21%)
Query: 448 GGPVNPLGPPVPHGPHGVPGPHGPPGPPG-PGTPMGPYNPAPYNP-GPPGPAPHGPPAPY 505
GG V G G GVPGP G GPPG P P P P P +P GP GPA P P
Sbjct: 510 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQ 569
Query: 506 APQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQT 565
P G P + P + G DP + +P P G P T
Sbjct: 570 GPPG-----PPGRDGTPGRDGEPG-DPG-------------EDGKPGDTGPQGFPGTPGD 610
Query: 566 NG-QGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAA 624
G +GD+ +P G+ + P P G P P + + + +
Sbjct: 611 VGPKGDKGDPG-VGE---------------RGPPGPQGPPGPPGPSFRHDKLTFIDMEGS 654
Query: 625 YY-----AQTSPQGMPQHPPAPQG 643
+ A P+G P PP P G
Sbjct: 655 GFGGDLEALRGPRGFP-GPPGPPG 677
Score = 48.1 bits (113), Expect = 2e-05
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 74/329 (22%)
Query: 349 GNPGGPGPGGRGRGRGQGNWN-MGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
G PG PGP G G G + G P + P G GL KG + + G
Sbjct: 775 GPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLP---G 831
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
A+ E+ + P G P + E I GP P G G G PG
Sbjct: 832 AKGEVGADGVPG---------FPGLPGR---------EGIAGPQGPKGDRGSRGEKGDPG 873
Query: 468 PH--------GPPGPPGPGTPMGPYNPAPYN-PGPPG-PAPHGPPAPYAPQG-------W 510
GPPGPPGP + + + + PGP G P G P P P+G
Sbjct: 874 KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGER 933
Query: 511 GNAYPHWQQQAP-----PD-----PAKAGT--DPNSAAWAAYYAHYYQQQAQPPPAAPAG 558
G+ P ++ P PD PA+ G +P Y + P P G
Sbjct: 934 GSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRP-G 992
Query: 559 APTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAP-PGGQPDY-SAAWA 616
P G+ + A G + + P P G P P G P Y S +A
Sbjct: 993 RPGMNGLKGEKGEPGDASLG----------FGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1042
Query: 617 EYYRQQAAYYAQTSPQGMP--QHPPAPQG 643
E R P G+P Q PP P+G
Sbjct: 1043 ESSR--------PGPPGLPGNQGPPGPKG 1063
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/318 (25%), Positives = 98/318 (30%), Gaps = 66/318 (20%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG- 407
G PG PGP GR GPPG + + G G KG +SG
Sbjct: 715 GLPGPPGPPGRE----------GPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGL 764
Query: 408 ARIELQRNPP----PNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPV--NPLGPPVPHG 461
A PP P P G P D E GGP P G
Sbjct: 765 AGAPGPAGPPGPPGPPGPPGP------GLPAGFDDM-----EGSGGPFWSTARSADGPQG 813
Query: 462 PHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG-PAPHGPPAPYAPQGWGNAYPHWQQQ 520
P G+PG G PG PG G A PG PG P G P P+G +
Sbjct: 814 PPGLPGLKGDPGVPGLPGAKGEVG-ADGVPGFPGLPGREGIAGPQGPKG-----DRGSRG 867
Query: 521 APPDPAKAGTD----PNSAAWAAYYAHYYQQQAQ----------------PPPAAPAGAP 560
DP K G P + +Q P PA P G
Sbjct: 868 EKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG-- 925
Query: 561 TTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYR 620
+G++ +P P G+ + + G PA GA G+P + Y R
Sbjct: 926 ---NLGSKGERGSPGPKGEKG--EPGSIFSPDGGALGPAQKGAK--GEPGFRGPPGPYGR 978
Query: 621 QQAAYYAQTSPQGMPQHP 638
Y + G P P
Sbjct: 979 --PGYKGEIGFPGRPGRP 994
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 71.2 bits (173), Expect = 3e-12
Identities = 45/152 (29%), Positives = 81/152 (53%), Gaps = 7/152 (4%)
Query: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSG-GLPERSCMLTGTPESVQSAK-RLL 164
+P VG IIG+ G I ++ + +G I+IAP G + ER ++TG PE+ A+ R+
Sbjct: 434 IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIF 493
Query: 165 DQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224
++ E+ F + I +P+S AG VIGKGG+T+ +LQ ++++ +D
Sbjct: 494 GKLKEEN-----FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 548
Query: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELIR 256
+ + +RI G + Q A+ + E+++
Sbjct: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQ 580
Score = 67.4 bits (163), Expect = 4e-11
Identities = 77/315 (24%), Positives = 123/315 (39%), Gaps = 71/315 (22%)
Query: 180 GDGPGNAVQ--------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA 231
G PG Q I++P G +IGK G TIK + ++ + V I + A
Sbjct: 180 GHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAA 238
Query: 232 DKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVI 291
+KP+ I P +A M+LE+++ + ++ E +I + G+ VG +I
Sbjct: 239 EKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGL--------VGRLI 290
Query: 292 GRNGEMIKKIQNDAGVRIQFKPDDGTT---PERIAQITGPPDRCQHA-AEII-------- 339
G+ G +KKI+++ G +I + PER + G + C A EI+
Sbjct: 291 GKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE 350
Query: 340 TDLLRSVQAGN--PG----------------GPGPGGRGRGRG----------------Q 365
D+L Q N PG P G RG
Sbjct: 351 NDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLY 410
Query: 366 GNWNMGPPGGLQEF------NFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPN 419
+ GP + N +PT G IIGK G IK +++ +GA I++ P
Sbjct: 411 PHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA--PAEG 468
Query: 420 ADPNMKLFTIRGTPQ 434
D + ++ I G P+
Sbjct: 469 PDVSERMVIITGPPE 483
Score = 67.0 bits (162), Expect = 5e-11
Identities = 81/336 (24%), Positives = 138/336 (41%), Gaps = 53/336 (15%)
Query: 92 MHQQQSRSVMTEEYKVP----DGMVGFIIGRGGEQISRIQQESGCKIQIAPD---SGGLP 144
M ++ + + EE + +G+VG +IG+ G + +I+ E+G KI I+ S P
Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
Query: 145 ERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKG 204
ER+ + GT E+ SA+ +I++K R A +++ +A L+ G
Sbjct: 322 ERTITVKGTVEACASAEI---EIMKKLREA-----------FENDMLAVNQQANLIPGLN 367
Query: 205 GETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREV 264
+ G+ ++ GP+ P P+ L G F
Sbjct: 368 LSALGIFS--TGLSVLSPPAGPRGAPPAAPYH----PFTTHSGYFSSLYPHHQFGPFPH- 420
Query: 265 RNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDG-TTPERIA 323
+ Y + E +++ IP AVG +IG+ G IK++ AG I+ P +G ER+
Sbjct: 421 HHSYPEQ----EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMV 476
Query: 324 QITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIV 383
ITGPP+ A I L+ NP E + V
Sbjct: 477 IITGPPEAQFKAQGRIFGKLKEENFFNP--------------------KEEVKLEAHIRV 516
Query: 384 PTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPN 419
P+ G +IGKGG+T+ + + A + + R+ P+
Sbjct: 517 PSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/177 (25%), Positives = 78/177 (44%), Gaps = 20/177 (11%)
Query: 178 HHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM-VMIQDGPQNTGADKPLR 236
HH P + + IP G +IGK G IKQL AG + + +GP +++ +
Sbjct: 420 HHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD--VSERMVI 477
Query: 237 ITGDPYKVQQAKEMVLELIRDQGGF---REVRNEYGSRIGGNEGIDVPIPRFAVGIVIGR 293
ITG P +A+ + ++++ F EV+ E + +P G VIG+
Sbjct: 478 ITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLE----------AHIRVPSSTAGRVIGK 527
Query: 294 NGEMIKKIQNDAGVRIQFKPDDGTTPER---IAQITGPPDRCQHAAEIITDLLRSVQ 347
G+ + ++QN + P D T E I +I G Q A I ++++ V+
Sbjct: 528 GGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 583
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 15/108 (13%)
Query: 347 QAGNPGGPGPGGRG--RGRGQGNWNMGPPGGLQE-------FNFIVPTGKTGLIIGKGGE 397
+ +P P RG R QG+ PGG + +VPT G IIGK G
Sbjct: 159 EVSSPSPPQRAQRGDHSSREQGH----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGL 214
Query: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEE 445
TIK+I++Q+ +R+++ R N+ K TI TP+ A ++I E
Sbjct: 215 TIKNITKQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260
Score = 38.1 bits (87), Expect = 0.025
Identities = 58/265 (21%), Positives = 92/265 (34%), Gaps = 54/265 (20%)
Query: 267 EYGSRIGGNEG---IDVP----IPRFAVGIVIGRNGEMIKKI--QNDAGVRIQFKPDDGT 317
E G GG ID P +P VG +IG+ G IK I Q + V I K + G
Sbjct: 178 EQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA 237
Query: 318 TPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQ 377
E+ I P+ A +I ++++ + + L+
Sbjct: 238 A-EKPVTIHATPEGTSEACRMILEIMQ------------------KEADETKLAEEIPLK 278
Query: 378 EFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQID 437
+ G G +IGK G +K I ++G +I + + + T++GT +
Sbjct: 279 ---ILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACA 335
Query: 438 YARQLIEEKIGGPVNPLGPPVPHGPHGVPGPH--------------GPPGPPGPGTPMGP 483
A I +K+ V + +PG + PP P P P
Sbjct: 336 SAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAP 395
Query: 484 YNPAPYNPG---------PPGPAPH 499
Y+P + G GP PH
Sbjct: 396 YHPFTTHSGYFSSLYPHHQFGPFPH 420
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 71.2 bits (173), Expect = 3e-12
Identities = 96/357 (26%), Positives = 119/357 (33%), Gaps = 92/357 (25%)
Query: 349 GNPGGPGPGGRGRGRG-QGNWNM----GPPGGLQEFNFIVPTGKTGLIIGKGGETIKSIS 403
G G GP G RG QG M GPPG + GK GL +G + +
Sbjct: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD------PGKPGLTGPQGPQGLPGTP 793
Query: 404 QQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPH 463
+ G + E + T+ G P GP P G P P GP
Sbjct: 794 GRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM---------GPPGPPGAPGPAGPA 844
Query: 464 GVPGPH------GPPGPPGPGTPMGPYNPAPYNP---------GPPGP------------ 496
G+PG GPPGPPGP P GP P P P GPPGP
Sbjct: 845 GLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904
Query: 497 -APHGPPAPYAPQG-WGNAYPHWQQ--------------------QAPP----------- 523
P GPP P P+G G P Q Q PP
Sbjct: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD 964
Query: 524 --DPAKAGT--DPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQ 579
DP G P+ + + Y P P P G P + ++GQ QQ + Q
Sbjct: 965 KGDPGVPGALGIPSGPSEGGSSSTMYVS-GPPGPPGPPGPPGSISSSGQEIQQYISEYMQ 1023
Query: 580 VDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEY--YRQQAAYYAQTSPQGM 634
D ++ Y Q P P G PPG + +Y Y +TS G+
Sbjct: 1024 SDSIRS----YLSGVQGPPGPPG-PPGPVTTITGETFDYSELASHVVSYLRTSGYGV 1075
Score = 68.6 bits (166), Expect = 2e-11
Identities = 91/363 (25%), Positives = 116/363 (31%), Gaps = 107/363 (29%)
Query: 349 GNPGGPG-PGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
G PG G PG G +G P G Q P G+ GL G
Sbjct: 722 GEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-----PRGEQGLTGMPG------------ 764
Query: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYA--RQLIEEKIGGP-----------VNPL 454
++ P P+ DP T PQ + R I+ + G P +
Sbjct: 765 ----IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVP 820
Query: 455 GPPVPHGPHGVPGPHGPP------------------GPPGPGTPMGPYNPAPYNPGPPGP 496
GPP P G G PGP G P GPPGP P GP P P PGPPGP
Sbjct: 821 GPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP--PGPSIPGPPGP 878
Query: 497 ---------------------------APHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAG 529
P GPP P P+G Q PP P
Sbjct: 879 RGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKG---------DQGPPGPRGHQ 929
Query: 530 TDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEY 589
+ ++ + + Q PP P +GD+ +P G + E
Sbjct: 930 GEQGLPGFSTSGSSSFGLNLQGPPGPPG------PQGPKGDKGDPGVPGALGIPSGPSEG 983
Query: 590 YKKMGQAVPAPTGAP-PGGQPDYSAAWAEYYRQQAAYYAQTSP--------QGMPQHPPA 640
V P G P P G P ++ + +Q + Y Q+ QG P PP
Sbjct: 984 GSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQG-PPGPPG 1042
Query: 641 PQG 643
P G
Sbjct: 1043 PPG 1045
Score = 60.1 bits (144), Expect = 6e-09
Identities = 87/353 (24%), Positives = 103/353 (29%), Gaps = 91/353 (25%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
G PG PGP G G PG + N P G G G SI G
Sbjct: 833 GPPGAPGPAGPA----------GLPGHQEVLNLQGPPGPPG----PRGPPGPSIPGPPGP 878
Query: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGP 468
R PP P G P E + GP P GPP P G G PGP
Sbjct: 879 R-----GPPGEGLP--------GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGP 925
Query: 469 HG------------------------PPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAP 504
G PPGPPGP P G +PG PG A P P
Sbjct: 926 RGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKG----DPGVPG-ALGIPSGP 980
Query: 505 YAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQ-----------QAQPPP 553
Y P P G+ +S Y Y Q Q P P
Sbjct: 981 SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP 1040
Query: 554 AAPAGAPTTT------------------QTNGQGDQQNPAPAGQVDYTKAWE-----EYY 590
P G TT +T+G G + D + +Y
Sbjct: 1041 PGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL 1100
Query: 591 KKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQG 643
++ P G PPG D S +Y + + S G+ P P G
Sbjct: 1101 RQYLMGPRGPPG-PPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPG 1152
Score = 50.1 bits (118), Expect = 6e-06
Identities = 92/367 (25%), Positives = 110/367 (29%), Gaps = 108/367 (29%)
Query: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLI--IGKGGETIKSISQQS 406
G PG PGP G +G G G + + P G+ G +G GE S +
Sbjct: 588 GTPGIPGPLGHPGPQGP----KGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEK 643
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPH--- 463
G R P P+ P G P + + G P GPP P G
Sbjct: 644 GER-GAAGEPGPHGPP--------GVPGSVG------PKGSSGSPGPQGPPGPVGLQGLR 688
Query: 464 ------GVPGPHGPPGPPGP-------------GTP-----------------MGPYNPA 487
GV G GP GPPGP G P MGP P
Sbjct: 689 GEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPD 748
Query: 488 PYNPGPPG-------PAPHGPPAPYAPQGW-GNAYPHWQQQAPPDPAKAGTDPNSAAWAA 539
+ GP G P GPP P G G P Q P P + G A
Sbjct: 749 GHQ-GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK 807
Query: 540 YYAHYYQQQ-------------------AQPPPAAPAGAPTTTQT-NGQGDQQNPAPAGQ 579
P PA PAG P + N QG P P G
Sbjct: 808 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRG- 866
Query: 580 VDYTKAWEEYYKKMGQAVPAPTG--APPG-GQPDYSAAWAEYYRQQAAYYAQTSPQGMPQ 636
G ++P P G PPG G P + + + P G P
Sbjct: 867 ------------PPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL--SGPPG-PP 911
Query: 637 HPPAPQG 643
PP P+G
Sbjct: 912 GPPGPKG 918
Score = 48.9 bits (115), Expect = 1e-05
Identities = 41/137 (29%), Positives = 49/137 (35%), Gaps = 30/137 (21%)
Query: 449 GPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGP--YNPAPYNPGPPGP-APHGPPAPY 505
GP +G P P G G PG G PGP G P GP + +PG GP G P
Sbjct: 570 GPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPM 629
Query: 506 APQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQT 565
P+G + PP + G AA +P P P G P +
Sbjct: 630 GPRG---------EAGPPGSGEKG--ERGAA------------GEPGPHGPPGVPGSVGP 666
Query: 566 NGQ----GDQQNPAPAG 578
G G Q P P G
Sbjct: 667 KGSSGSPGPQGPPGPVG 683
Score = 44.3 bits (103), Expect = 4e-04
Identities = 58/226 (25%), Positives = 82/226 (36%), Gaps = 67/226 (29%)
Query: 340 TDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGL-----QEFNF---------IVPT 385
+D +RS +G G PGP G PPG + + F++ + T
Sbjct: 1024 SDSIRSYLSGVQGPPGPPG-------------PPGPVTTITGETFDYSELASHVVSYLRT 1070
Query: 386 GKTGLIIGKGG---ETIKSISQQSGARIELQRN-PPPNADPNMKLFTIRGTPQQIDYAR- 440
G+ + E I ++ Q+ R L++ P P + G+ +DYA
Sbjct: 1071 SGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAEL 1130
Query: 441 -QLIEEKIGGPVNPLGPPVPHGPHGVPGPH-----------------GPPGPPGP-GTPM 481
I + +G P P GP G+PG GPPGPPGP G P
Sbjct: 1131 SSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPG 1190
Query: 482 GPYNPAP--------------YNPGPPGPAPHGPPAPYAPQGWGNA 513
++ + PGPPGP GPP P P G A
Sbjct: 1191 NVWSSISVEDLSSYLHTAGLSFIPGPPGPP--GPPGPRGPPGVSGA 1234
Score = 43.1 bits (100), Expect = 8e-04
Identities = 21/45 (46%), Positives = 22/45 (48%), Gaps = 10/45 (22%)
Query: 455 GPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPH 499
GPP G G PGP G GP GP P +PGPPGP H
Sbjct: 1438 GPPGQKGEMGTPGPKGDRGPAGP----------PGHPGPPGPRGH 1472
Score = 38.5 bits (88), Expect = 0.019
Identities = 23/63 (36%), Positives = 24/63 (38%), Gaps = 17/63 (26%)
Query: 457 PVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNP----------------GPPG-PAPH 499
P P GP G PGP GPPG G N + GPPG P P
Sbjct: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273
Query: 500 GPP 502
GPP
Sbjct: 1274 GPP 1276
Score = 38.1 bits (87), Expect = 0.025
Identities = 46/162 (28%), Positives = 61/162 (37%), Gaps = 35/162 (21%)
Query: 348 AGNPGGPGPGGRGRG-RGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGG---------- 396
AG+ G G G G RG ++GP GG + G+ G GG
Sbjct: 1318 AGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGA------AAEGGMYAGNGGLLGADFAGDL 1371
Query: 397 ---ETIKSISQQSGARIELQ------RNPP----PNADPNM-KLFTIRG--TPQQIDYAR 440
E +S+ + LQ + PP P P + K+F+ T +D+ +
Sbjct: 1372 DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQ 1431
Query: 441 QLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMG 482
I GP G GP G GP GPPG PGP P G
Sbjct: 1432 TY--GAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRG 1471
Score = 36.6 bits (83), Expect = 0.074
Identities = 26/77 (33%), Positives = 28/77 (36%), Gaps = 29/77 (37%)
Query: 461 GPHGVPGPHGPPG---------------------------PPGPGTPMGPYNPAPYNPGP 493
GP G PGP GPPG PPG MG P + GP
Sbjct: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKG-DRGP 1457
Query: 494 PGPAPH-GPPAPYAPQG 509
GP H GPP P +G
Sbjct: 1458 AGPPGHPGPPGPRGHKG 1474
Score = 30.4 bits (67), Expect = 5.3
Identities = 12/15 (80%), Positives = 13/15 (86%)
Query: 11 SSGSAGGGGGGGGGG 25
S GS+GGGG GGGGG
Sbjct: 426 SYGSSGGGGSGGGGG 440
Score = 29.6 bits (65), Expect = 9.0
Identities = 14/28 (50%), Positives = 14/28 (50%)
Query: 449 GPVNPLGPPVPHGPHGVPGPHGPPGPPG 476
G P G P GP G PGP GP G G
Sbjct: 1447 GTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/362 (23%), Positives = 146/362 (40%), Gaps = 40/362 (11%)
Query: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
Query: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 142 TERAITIAGIPQSIIECVKQICVVMLET-----------LSQSPPKGVTIPYRPKPSSSP 190
Query: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRC-----QHAAEIITDLLR 344
VI G+ +D+ P P+ + GPP Q+A DL +
Sbjct: 191 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPD----LEGPPLEAYTIQGQYAIP-QPDLTK 245
Query: 345 SVQAGNPGGPGPGGRGRGRGQGNWNMGPP-----GGLQ------EFNFIVPTGKTGLIIG 393
Q P G G + P GL +P G IIG
Sbjct: 246 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIG 305
Query: 394 KGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNP 453
+ G I I Q SGA+I++ + D + TI G+ I A+ LI ++
Sbjct: 306 RQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGG 362
Query: 454 LG 455
+G
Sbjct: 363 MG 364
Score = 69.7 bits (169), Expect = 8e-12
Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 26/187 (13%)
Query: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
Query: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQ----LIEEKIGGPVNPLGPPVPHG 461
GA++++ + PN+ + TI G PQ I+ +Q ++E P P G +P+
Sbjct: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLETLSQSP--PKGVTIPYR 183
Query: 462 PHGVPGP 468
P P
Sbjct: 184 PKPSSSP 190
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 285 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 344
Query: 157 VQSAKRLLD 165
+ A+ L++
Sbjct: 345 ISLAQYLIN 353
Score = 44.3 bits (103), Expect = 4e-04
Identities = 62/279 (22%), Positives = 107/279 (38%), Gaps = 36/279 (12%)
Query: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
Query: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
P+S ++ K++ ++E +P P S + ++ G +
Sbjct: 152 PQSIIECVKQICVVMLETLSQSP-------PKGVTIPYRPKPSSSPVIFAGGQDRYSTGS 204
Query: 213 ERAGVKMV--MIQDGPQNTGADKPLRITGDPYKVQQ----------AKEMVLELIRDQGG 260
+ A + P G Y + Q ++ + G
Sbjct: 205 DSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTG 264
Query: 261 FREVRNEYGSRIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF 311
F + + G G+D + IP +G +IGR G I +I+ +G +I+
Sbjct: 265 FSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKI 324
Query: 312 -KPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
P +G+T +R ITG A +I L S G
Sbjct: 325 ANPVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 362
Score = 43.9 bits (102), Expect = 5e-04
Identities = 36/166 (21%), Positives = 77/166 (46%), Gaps = 8/166 (4%)
Query: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
Query: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 310 QFKPDD-GTTPERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGG 353
Q D + ER I G P + +I +L ++ P G
Sbjct: 132 QVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
Query: 447 I 447
+
Sbjct: 79 L 79
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.136 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,378,433
Number of Sequences: 37866
Number of extensions: 2882397
Number of successful extensions: 55108
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 779
Number of HSP's successfully gapped in prelim test: 1080
Number of HSP's that attempted gapping in prelim test: 15785
Number of HSP's gapped (non-prelim): 13876
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.