BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|171543895 ataxin 2 [Homo sapiens] (1313 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|171543895 ataxin 2 [Homo sapiens] 2687 0.0 gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] 621 e-177 gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 610 e-174 gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 610 e-174 gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] 610 e-174 gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] 610 e-174 gi|163965366 nascent polypeptide-associated complex alpha subuni... 95 5e-19 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 93 2e-18 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 84 7e-16 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 84 7e-16 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 84 7e-16 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 1e-14 gi|151301154 mucin 6, gastric [Homo sapiens] 77 8e-14 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 77 8e-14 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 2e-13 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 74 7e-13 gi|55750053 atrophin-1 [Homo sapiens] 73 2e-12 gi|55750041 atrophin-1 [Homo sapiens] 73 2e-12 gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 71 6e-12 gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 71 6e-12 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 70 1e-11 gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 70 1e-11 gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 70 1e-11 gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 70 1e-11 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 68 5e-11 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 68 5e-11 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 68 5e-11 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 68 5e-11 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 68 5e-11 gi|150170670 piccolo isoform 2 [Homo sapiens] 68 5e-11 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 2687 bits (6966), Expect = 0.0 Identities = 1313/1313 (100%), Positives = 1313/1313 (100%) Query: 1 MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGP 60 MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGP Sbjct: 1 MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGP 60 Query: 61 GPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAA 120 GPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAA Sbjct: 61 GPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAA 120 Query: 121 PTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ 180 PTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ Sbjct: 121 PTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ 180 Query: 181 QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRP 240 QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRP Sbjct: 181 QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRP 240 Query: 241 GLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPK 300 GLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPK Sbjct: 241 GLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPK 300 Query: 301 CDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA 360 CDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA Sbjct: 301 CDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA 360 Query: 361 KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLS 420 KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLS Sbjct: 361 KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLS 420 Query: 421 SYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSE 480 SYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSE Sbjct: 421 SYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSE 480 Query: 481 REGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG 540 REGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG Sbjct: 481 REGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG 540 Query: 541 SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPS 600 SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPS Sbjct: 541 SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPS 600 Query: 601 AHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT 660 AHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT Sbjct: 601 AHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT 660 Query: 661 PPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV 720 PPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV Sbjct: 661 PPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV 720 Query: 721 AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAEN 780 AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAEN Sbjct: 721 AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAEN 780 Query: 781 KGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSA 840 KGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSA Sbjct: 781 KGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSA 840 Query: 841 KDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE 900 KDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE Sbjct: 841 KDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE 900 Query: 901 EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQ 960 EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQ Sbjct: 901 EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQ 960 Query: 961 PVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPA 1020 PVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPA Sbjct: 961 PVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPA 1020 Query: 1021 SAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPP 1080 SAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPP Sbjct: 1021 SAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPP 1080 Query: 1081 THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATL 1140 THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATL Sbjct: 1081 THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATL 1140 Query: 1141 HPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAP 1200 HPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAP Sbjct: 1141 HPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAP 1200 Query: 1201 TPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHP 1260 TPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHP Sbjct: 1201 TPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHP 1260 Query: 1261 TAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL 1313 TAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL Sbjct: 1261 TAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL 1313 >gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] Length = 1044 Score = 621 bits (1602), Expect = e-177 Identities = 461/1206 (38%), Positives = 619/1206 (51%), Gaps = 225/1206 (18%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 Query: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 Query: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 Query: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 Query: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 Query: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 Query: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 Query: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 ++ P R A T + P +RP S PP P + P Sbjct: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 Query: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 +SP ASP+ + PT+ ++ P + P A Sbjct: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 Query: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P + + R Q Q + P+ + EN + P K E KG Sbjct: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K++D L TSE M ++ E ++ K + PS Sbjct: 580 EKEVDGL------------LTSEPMGSPVSSKTESVSDKE-DKPPLAPSGG--------- 617 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 T G +P P S QT SP K + +++ AEQV+ Sbjct: 618 --TEGPEQPPPPCPS--------------------QTGSPPVGLIKGEDKDEGPVAEQVK 655 Query: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 Query: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 Query: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 Query: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 Query: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 Query: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 Query: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP VQ+ Sbjct: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQS 1031 Query: 1308 HHQQQL 1313 H QQL Sbjct: 1032 HPSQQL 1037 Score = 39.3 bits (90), Expect = 0.025 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 Query: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 Query: 230 VVAATSGGGRPGLG 243 TS PG+G Sbjct: 480 ---VTSSVSDPGVG 490 Score = 35.4 bits (80), Expect = 0.36 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 Query: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 NG R L G L P RP +P P A PP +P A+P Sbjct: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 Query: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 AS P + A P P V P S+ P Sbjct: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 Score = 33.9 bits (76), Expect = 1.1 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Query: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 G+ +L PP PGA R G PP+S V Sbjct: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 >gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] Length = 1062 Score = 610 bits (1572), Expect = e-174 Identities = 455/1196 (38%), Positives = 612/1196 (51%), Gaps = 225/1196 (18%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 Query: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 Query: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 Query: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 Query: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 Query: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 Query: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 Query: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 ++ P R A T + P +RP S PP P + P Sbjct: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 Query: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 +SP ASP+ + PT+ ++ P + P A Sbjct: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 Query: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P + + R Q Q + P+ + EN + P K E KG Sbjct: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K++D L TSE M ++ E ++ K + PS Sbjct: 580 EKEVDGL------------LTSEPMGSPVSSKTESVSDKE-DKPPLAPSGG--------- 617 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 T G +P P S QT SP K + +++ AEQV+ Sbjct: 618 --TEGPEQPPPPCPS--------------------QTGSPPVGLIKGEDKDEGPVAEQVK 655 Query: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 Query: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 Query: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 Query: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 Query: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 Query: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 Query: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP Sbjct: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027 Score = 39.3 bits (90), Expect = 0.025 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 Query: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 Query: 230 VVAATSGGGRPGLG 243 TS PG+G Sbjct: 480 ---VTSSVSDPGVG 490 Score = 35.4 bits (80), Expect = 0.36 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 Query: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 NG R L G L P RP +P P A PP +P A+P Sbjct: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 Query: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 AS P + A P P V P S+ P Sbjct: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 Score = 33.9 bits (76), Expect = 1.1 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Query: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 G+ +L PP PGA R G PP+S V Sbjct: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 >gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] Length = 1044 Score = 610 bits (1572), Expect = e-174 Identities = 455/1196 (38%), Positives = 612/1196 (51%), Gaps = 225/1196 (18%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 Query: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 Query: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 Query: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 Query: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 Query: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 Query: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 Query: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 ++ P R A T + P +RP S PP P + P Sbjct: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 Query: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 +SP ASP+ + PT+ ++ P + P A Sbjct: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 Query: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P + + R Q Q + P+ + EN + P K E KG Sbjct: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K++D L TSE M ++ E ++ K + PS Sbjct: 580 EKEVDGL------------LTSEPMGSPVSSKTESVSDKE-DKPPLAPSGG--------- 617 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 T G +P P S QT SP K + +++ AEQV+ Sbjct: 618 --TEGPEQPPPPCPS--------------------QTGSPPVGLIKGEDKDEGPVAEQVK 655 Query: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 Query: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 Query: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 Query: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 Query: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 Query: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 Query: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP Sbjct: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027 Score = 39.3 bits (90), Expect = 0.025 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 Query: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 Query: 230 VVAATSGGGRPGLG 243 TS PG+G Sbjct: 480 ---VTSSVSDPGVG 490 Score = 35.4 bits (80), Expect = 0.36 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 Query: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 NG R L G L P RP +P P A PP +P A+P Sbjct: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 Query: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 AS P + A P P V P S+ P Sbjct: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 Score = 33.9 bits (76), Expect = 1.1 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Query: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 G+ +L PP PGA R G PP+S V Sbjct: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 >gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] Length = 1097 Score = 610 bits (1572), Expect = e-174 Identities = 455/1196 (38%), Positives = 612/1196 (51%), Gaps = 225/1196 (18%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 Query: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 Query: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 Query: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 Query: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 Query: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 Query: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 Query: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 ++ P R A T + P +RP S PP P + P Sbjct: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 Query: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 +SP ASP+ + PT+ ++ P + P A Sbjct: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 Query: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P + + R Q Q + P+ + EN + P K E KG Sbjct: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K++D L TSE M ++ E ++ K + PS Sbjct: 580 EKEVDGL------------LTSEPMGSPVSSKTESVSDKE-DKPPLAPSGG--------- 617 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 T G +P P S QT SP K + +++ AEQV+ Sbjct: 618 --TEGPEQPPPPCPS--------------------QTGSPPVGLIKGEDKDEGPVAEQVK 655 Query: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 Query: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 Query: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 Query: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 Query: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 Query: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 Query: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP Sbjct: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027 Score = 39.3 bits (90), Expect = 0.025 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 Query: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 Query: 230 VVAATSGGGRPGLG 243 TS PG+G Sbjct: 480 ---VTSSVSDPGVG 490 Score = 35.4 bits (80), Expect = 0.36 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 Query: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 NG R L G L P RP +P P A PP +P A+P Sbjct: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 Query: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 AS P + A P P V P S+ P Sbjct: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 Score = 33.9 bits (76), Expect = 1.1 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Query: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 G+ +L PP PGA R G PP+S V Sbjct: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 >gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] Length = 1075 Score = 610 bits (1572), Expect = e-174 Identities = 455/1196 (38%), Positives = 612/1196 (51%), Gaps = 225/1196 (18%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 Query: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 Query: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 Query: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 Query: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 Query: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 Query: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 Query: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 ++ P R A T + P +RP S PP P + P Sbjct: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 Query: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 +SP ASP+ + PT+ ++ P + P A Sbjct: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 Query: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P + + R Q Q + P+ + EN + P K E KG Sbjct: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K++D L TSE M ++ E ++ K + PS Sbjct: 580 EKEVDGL------------LTSEPMGSPVSSKTESVSDKE-DKPPLAPSGG--------- 617 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 T G +P P S QT SP K + +++ AEQV+ Sbjct: 618 --TEGPEQPPPPCPS--------------------QTGSPPVGLIKGEDKDEGPVAEQVK 655 Query: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 Query: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 Query: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 Query: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 Query: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 Query: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 Query: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP Sbjct: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027 Score = 39.3 bits (90), Expect = 0.025 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 Query: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 Query: 230 VVAATSGGGRPGLG 243 TS PG+G Sbjct: 480 ---VTSSVSDPGVG 490 Score = 35.4 bits (80), Expect = 0.36 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 Query: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 NG R L G L P RP +P P A PP +P A+P Sbjct: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 Query: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 AS P + A P P V P S+ P Sbjct: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 Score = 33.9 bits (76), Expect = 1.1 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Query: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 G+ +L PP PGA R G PP+S V Sbjct: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 94.7 bits (234), Expect = 5e-19 Identities = 191/834 (22%), Positives = 278/834 (33%), Gaps = 127/834 (15%) Query: 548 GGVPWPSP--CPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP 605 GG PSP P+P + P + GP + P+ A PT P + PPS P P+ PS G+P Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA-PTPPAATPPS-PKGGPATPSPKGAP 1009 Query: 606 APVSTMPKRMSSEGPPRMSPKAQRHPRNHRV-SAGRGSISSGLEFVSHNPPSEAATPPVA 664 P + P P+ SP A P+ A G + P TP Sbjct: 1010 TPPAVTPP------SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063 Query: 665 RTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL------ASPQAGI-IPT 717 SP GG + + G P +P P SP+ +P G + SP+ G+ P Sbjct: 1064 LPSPKGGPATPSLKGAP--TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121 Query: 718 EAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN--ETSPSF 775 A PAA TP SP A P A + SP G P T+P+ Sbjct: 1122 HKGAPTTPAA--TPPSPKGGLATPPPKGAPTT--PAATPPSPKGGLATPPPKGAPTTPAA 1177 Query: 776 SKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDK 835 + KG S P++T S L K Sbjct: 1178 TPPSPKGGLATPS------------PKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAA 1223 Query: 836 IEPSAKDSFIENSSSNC-TSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQ 894 PS K S T+ ++ P SP P+ P T ++ Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283 Query: 895 EKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQP 954 + +P P + + P P +P +P P+ P+P V P Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343 Query: 955 TPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPM----PVNQAKTYRAVPNMPQQRQDQ 1010 T P + P S P P TP P + + P +P + D Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPT-PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402 Query: 1011 HHQSAM-MHPASAAGPPI----AATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHV 1065 + + + P A P+ AATP A +P ++ P + Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS------LKKAPATSAPKGGP 1456 Query: 1066 YSPVIQGNARMMA--PPTHAQPGLVSSSATQYGAHE--QTHAMYACPKLPYNKETSPSFY 1121 +P +G+ + A PP+ +P AT + T A P LP +SP Sbjct: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV 1516 Query: 1122 FAISTGSLAQQYAHPNATL----------------HPHTPHPQPSATPT--------GQQ 1157 A T S + P ATL P P P TP Sbjct: 1517 PA--TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574 Query: 1158 QSQHGGSHPAPSPVQHHQHQAAQAL----HLASPQQQSAIYHAGLAPTPPSMTPASNTQS 1213 S+ S PA +P + + + L + SP + APTPP++TP S + Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE-------APTPPAVTPPSPEKG 1627 Query: 1214 PQNSFPAAQQTVFTIHPSHVQPAYTNPPHM-----AHVPQAHVQSGM-VPSHPTAHAPMM 1267 P P T + PS ++ + T+P + A VPQA G+ PTA ++ Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA--SKGLPAKKGPTALKEVL 1685 Query: 1268 ---------LMTTQPPGGPQAALAQSALQPI------------PVSTTAHFPYM 1300 ++T GPQ + + PI P+ST A P + Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLL 1739 Score = 74.3 bits (181), Expect = 7e-13 Identities = 163/716 (22%), Positives = 229/716 (31%), Gaps = 95/716 (13%) Query: 606 APVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVAR 665 AP S ++++ P + P Q P+N S S SS E + +P + A + Sbjct: 542 APFSPAQAGLTTKKDPTVLPLVQAAPKN---SPSFQSTSSSPE-IPLSPEATLAKKSLGE 597 Query: 666 TSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIP 725 P G SS+ S L + + G +GP+L S I PT A A P+ Sbjct: 598 PLPIGKPASSMTSP---LGVNSSASVIKTDSYAGPDSAGPLLKSSL--ITPTVA-AFPLE 651 Query: 726 AASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISP 785 +A P +P + + + + L+ +P + T P A P Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN--CP 709 Query: 786 VVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFI 845 V + L + S S S+ G D I ++ + + Sbjct: 710 VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA------GTPPGTKKVDGISHTSALAPV 763 Query: 846 ENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEK--- 902 +S C + S ++ + S L+ P S QT P K+ + Sbjct: 764 ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN 823 Query: 903 -KDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTT--PTSPRPQAQPSPSMVGHQQP----T 955 V S L N+ F S+ P+TT PT P P+ P+PS V P Sbjct: 824 LSSPVSPVEASFLPENSLSFQG---SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880 Query: 956 PVYTQPVCFAPNMMYPV--PVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQ 1013 P P N+ +P P +P + + MT +A+ A +P Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP--------- 931 Query: 1014 SAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGN 1073 A P A PP AATPP+ SP+ P P P P SP Sbjct: 932 -ASPSPKGAPTPP-AATPPSPKGGPATPSPKWAPTPPAA--TPPSPKGGPATPSP----- 982 Query: 1074 ARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQY 1133 PP P AT P T P+ GS Sbjct: 983 KGAPTPPAATPPSPKGGPAT---------------PSPKGAPTPPAVTPPSPKGS----- 1022 Query: 1134 AHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAI 1193 P AT P P+ATP + S P +P A L SP+ A Sbjct: 1023 --PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP-------TTPAATLPSPKGGPAT 1073 Query: 1194 YHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQS 1253 APTPP+ TP S P P P + PPH Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG--------- 1124 Query: 1254 GMVPSHPTAHAPMML--MTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307 P+ P A P + T PP G A +A P P A P P+ A Sbjct: 1125 --APTTPAATPPSPKGGLATPPPKG--APTTPAATPPSPKGGLATPPPKGAPTTPA 1176 Score = 73.9 bits (180), Expect = 9e-13 Identities = 131/530 (24%), Positives = 200/530 (37%), Gaps = 96/530 (18%) Query: 555 PCPSPSSRPPSRYQSGPNSLPPRAATPTRP--PSRPPSRPSRPPSHPSAHG---SPAPVS 609 P +PSS+ S P AATP+ P+ P P R P+ PS G SPA + Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409 Query: 610 TMPKR-----MSSEG----------PPRMSPKA-QRHPRNHRVSAGRGSISSG----LEF 649 PK+ ++ EG PP ++P + ++ P G + SS L Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469 Query: 650 VSHNPPSEAATPPVARTSPS------------GGTWSSVVSGVPRLSPKTHRPRSPRQNS 697 V+ P E P TS S T +V+ P+ P T S R++ Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP---SSRRDP 1526 Query: 698 IGNTPS-----GPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA-VTPSSEAKDSR- 750 I T + P +P+ +IP AM +P+ TPA P A TPSS+ S Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPP---AMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583 Query: 751 --LQDQRQNSPAGNKENIKPNETSPSFSKAENK-GISPVVSEHRKQIDDLKKFKNDFRLQ 807 + +P+ + I P TSPS +A ++P E K + Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT 1643 Query: 808 PSSTSESMDQ-------------LLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTS 854 PSS +S +K +K +K+ + A +S ++ Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES-TPIITAPTRK 1702 Query: 855 GSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEK-KDAAEQVRKST 913 G S + SP I + K G + V + Q+ K K KDA+ + Sbjct: 1703 GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL 1762 Query: 914 LNPNAKEFNPRSFSQ-----PKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 P +K P + + PKP + S A PSP + P+PV T P P Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVS----AAPSPPVSLPLAPSPVPTLP----PKQ 1814 Query: 969 MYPVPVSPGV------QPLYP------IPM-TPMPVNQAKTYRAV-PNMP 1004 + +P SPG+ +PL P +P+ P P++ +++V NMP Sbjct: 1815 QF-LPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMP 1863 Score = 65.9 bits (159), Expect = 3e-10 Identities = 189/839 (22%), Positives = 270/839 (32%), Gaps = 138/839 (16%) Query: 553 PSPCPSPSSRPPSRYQ----SGPNSLPPRAATPTRPPSRPPSRPSRPPSHPS---AHGSP 605 PSP P+ PP + S ++L P A++P P+ + S + SP Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794 Query: 606 APVSTM--------PKRMSSEGP---------PRMSPKAQRHPRNHRVSAGRGSISSGLE 648 +P+ P + S GP P +A P N + +GS S Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS--LSFQGSKDSPAT 852 Query: 649 FVSHNPPSEAATP---PVARTSPSGGTW--------SSVVSGVPRLSPKTHRPR------ 691 S PPS P V SP G T S V P+ P T P+ Sbjct: 853 THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912 Query: 692 ----SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAK 747 SP++ P G + ASP PT A P P+ PA+P+ A TP + Sbjct: 913 MTSSSPKKARATPAPKG-IPASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTPPAATP 970 Query: 748 DSRLQDQRQNSPAGNKENIKPNETSPSFSKA--ENKGI---SPVVSEHRKQIDDLKKFKN 802 S SP G SP A KG V K F Sbjct: 971 PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030 Query: 803 DFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSK--PN 860 P++T S +G + + K P+ + + + + S K P Sbjct: 1031 GASTPPAATPPS--------PKGSPAATPL-PKGAPTTPAATLPSPKGGPATPSLKGAPT 1081 Query: 861 SPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRK-STLNPNAK 919 P+ +P K GP S PA K A K + P A Sbjct: 1082 PPAATP-----PSPKGGPATPSPKGAPMPPAA----TPPSPKGGLATPPHKGAPTTPAAT 1132 Query: 920 EFNPR-SFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPN----MMYP--- 971 +P+ + P P PT+P + P T P P+ + P Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192 Query: 972 -VPVSPGVQPLYPIP----MTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPP 1026 P +P P P P TP P T A P P + + P+ P Sbjct: 1193 GAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSP--------KGGLATPSPKGAPT 1242 Query: 1027 I-AATPPAYSTQYVAYSPQQFPNQPL---------VQHVPHYQSQHPHVYSPVIQGNARM 1076 AATPP+ P+ P P + PH + +P V +P Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302 Query: 1077 MAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 +PP A ++ + G+ T P P SP G+ P Sbjct: 1303 TSPPKGAPTPPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPK-------GTPTLPATTP 1354 Query: 1137 NATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQA---------AQALHLASP 1187 ++ P TP + TP S GG PA +P + A + A+ SP Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGG--PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412 Query: 1188 QQQSA--IYHAGLAP------TPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTN 1239 ++ A + G A TPP++TP S ++P S P + PA T Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472 Query: 1240 P-PHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQP--PGGPQAALAQSALQPIPVSTTA 1295 P P P+ S P APM T P P+ A + + P++ TA Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531 Score = 57.8 bits (138), Expect = 7e-08 Identities = 70/263 (26%), Positives = 87/263 (33%), Gaps = 30/263 (11%) Query: 7 APRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGP------YPSAAPPPPG- 59 AP +PA S + A P + PA GG A P P+A PP P Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184 Query: 60 -------PGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGG--PPRPFVVLLLP 110 G P + ++PPS + G P + GG P P P Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244 Query: 111 LASPGAPPAAPTRASPLGA----RASPPRSGVSLARPA-PGCPRPAC----EPVYGPLTM 161 A+P +P P P GA A+PP LA P G P PA P GP T Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304 Query: 162 SLK--PQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSV 219 K P + + PPA V P G PA PS Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA---VTPPSPKGTPTLPATTPSSKGGPT 1361 Query: 220 SSSSATAPSSVVAATSGGGRPGL 242 + SS P+ A S G P + Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAM 1384 Score = 54.7 bits (130), Expect = 6e-07 Identities = 75/289 (25%), Positives = 92/289 (31%), Gaps = 43/289 (14%) Query: 3 SAAAAPRSPAVATESRRFAAAR-WPGWRSLQRPARRSGRGGGGAAPGPY-----PSAAPP 56 S AP PA S + A P W A GG A P P P+A PP Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994 Query: 57 PPGPGP---------------PPSRQSSPPSASDCFGSNGNGGGAFRPGSRR------LL 95 P GP PPS + SP A+ F + A P S + L Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSP--AATPFPKGASTPPAATPPSPKGSPAATPL 1052 Query: 96 GLGGPPRPFVVLLLPLASPGAP-------PAAPTRASPLGARASPPRSGVSLARPAPGCP 148 G P P L P P P P A T SP G A+P G + PA P Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP-PAATPP 1111 Query: 149 RP----ACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGL 204 P A P G T + + PP + P G Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171 Query: 205 LASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLP 253 +PAA P +++ S + AAT + GL S KG P Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL--ATPSPKGAP 1218 Score = 51.2 bits (121), Expect = 6e-06 Identities = 120/537 (22%), Positives = 192/537 (35%), Gaps = 79/537 (14%) Query: 557 PSPSSRPPSRYQSGPNSLPPRAATPTRP---PSRPPSRPSRPPSHPSAHGSPAPVSTMPK 613 P P+ PP P P AA P PS S P P S+ G+ P+ T P+ Sbjct: 41 PGPTLPPPC--SPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPE 98 Query: 614 R----MSSEGPPRMSPK--AQRHPRNHRVSAGRGSISSGLEFVS---HNPPSEAATPPVA 664 + GPP +SP A P G S S+ L V+ H+ +A PP Sbjct: 99 APTFLPNLIGPP-ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNL 157 Query: 665 RTSP------SGGTWSSVVSGVPRLSPKTHRPRSPRQ---NSIGNTPSGPVLASPQAGII 715 TSP G+ ++ + + PKT+ + P + N G TPS P + S Sbjct: 158 LTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG-TPSPPCIVSTVPYHC 216 Query: 716 PTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSF 775 T ++ AS +P + A+ S + KD+ + + ++K + P+ Sbjct: 217 VTPMASIQSGVASLPQTTPTTTLAIA-SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAA 275 Query: 776 SKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNRE--GEKSRDLIK 833 + + PVV+ +K DF + S + Q + + G+ + Sbjct: 276 LSLSTQSL-PVVTSSQKTAG--PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALS 332 Query: 834 DKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTE---------------HKRGP 878 D P+ K +++SS +G+S P+ S+ P + S E +GP Sbjct: 333 D---PTVKTISVDHSS----TGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGP 385 Query: 879 EVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSP 938 S T SP+ + KS +PNA P P S T Sbjct: 386 STISS--ITCSPSGSLNVATSFSLSPTTSLILKS--SPNATYHYPLVAQMPVSSVGTT-- 439 Query: 939 RPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMY-PV----PVSPGVQPLYPIPMTPMPVNQ 993 P +P + PT + C +P M P+ P SP + P+ Sbjct: 440 -PLVVTNPCTIA-AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497 Query: 994 AKTYR--AVPNMPQQRQDQHHQSAMM-----------HPASAAGPPIAATPPAYSTQ 1037 A T R P +P ++ S+++ PAS G P + +T+ Sbjct: 498 ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK 554 Score = 47.0 bits (110), Expect = 1e-04 Identities = 61/257 (23%), Positives = 86/257 (33%), Gaps = 27/257 (10%) Query: 3 SAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSA------APP 56 S AP +PA S + A P + PA GG A P+ A PP Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295 Query: 57 PPGPGP---PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLAS 113 P GP PP +PP+A+ S G P PP P LP + Sbjct: 1296 SPKGGPATSPPKGAPTPPAATP--PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353 Query: 114 P---GAPPAAPTRASPLGARASPPRSGVSLARP-----APGCPRPACEPVYGPLTMSLKP 165 P G P ++ P A+P G P P P P +P P + L P Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT-SPAVIPLSP 1412 Query: 166 QQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRK-PGGSGLLASPAAAPS------PSSSS 218 ++ ++ + P +++K P S PA S P+ + Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472 Query: 219 VSSSSATAPSSVVAATS 235 S AP V ++S Sbjct: 1473 PSPKEPPAPKQVATSSS 1489 Score = 46.2 bits (108), Expect = 2e-04 Identities = 59/226 (26%), Positives = 77/226 (34%), Gaps = 31/226 (13%) Query: 44 GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRP 103 G+ P + +P PP P P+ + P + G P P P Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK---------GVTLPPKET-------PTP 888 Query: 104 FVVLL-LPLASPG--APPAAP----TRASPLGARASPPRSGVSLARPAPGCPRPAC---- 152 VV L P P AP AP T +SP ARA+P G+ + G P P Sbjct: 889 SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP 948 Query: 153 EPVYGPLTMSLK-PQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAA 211 P GP T S K + + P P AA P G SP A Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008 Query: 212 PSP---SSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQ 254 P+P + S S A P A+T P +G + LP+ Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054 Score = 44.3 bits (103), Expect = 8e-04 Identities = 52/193 (26%), Positives = 71/193 (36%), Gaps = 16/193 (8%) Query: 45 AAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPF 104 A P AA P G PP+ +P S ++ GG P S+ G P P Sbjct: 1417 ATPVTREGAATPSKGDLTPPA--VTPVSLKKAPATSAPKGGPATPSSK-----GDPTLPA 1469 Query: 105 VVLLLPLASPGAPPAAPTRASPLGARASP-PRSGVSLARPAPGCPRPACEPVYGPLTMSL 163 V P P AP T +SP A A+P P +L P P+ P T S Sbjct: 1470 VTPPSP-KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV------PATPSS 1522 Query: 164 KPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-PSSSSVSSS 222 + ++ ++ P A V P + + +P AP+ PSS SS Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582 Query: 223 SATAPSSVVAATS 235 A PS+ A S Sbjct: 1583 PAVTPSTYKGAPS 1595 Score = 42.4 bits (98), Expect = 0.003 Identities = 68/254 (26%), Positives = 88/254 (34%), Gaps = 36/254 (14%) Query: 7 APRSPAVATESRRFAAARWPGWRSLQRPARR--SGRGGGGAAP---GPYPSAAPPPPGPG 61 AP V S + A P + PA S +G G P P P A PP G Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345 Query: 62 PP------PSRQSSPPSASDCFGS-------NGNGGGAFRPGSRRL-----LGLGGPPRP 103 P PS + P + S G + GG A P S + G P P Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405 Query: 104 FVVLLLPLASPGAPPAAPTRASPLGARASPPR-SGVSLAR-PAPGCPRPACEPVYGPLTM 161 V+ L P +P P A+P +PP + VSL + PA P+ GP T Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG------GPATP 1459 Query: 162 SLK--PQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAP-SPSSSS 218 S K P ++ +Q P A P G+ L PA P SP Sbjct: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL--PAVIPSSPKEVP 1517 Query: 219 VSSSSATAPSSVVA 232 + SS P + A Sbjct: 1518 ATPSSRRDPIAPTA 1531 Score = 39.7 bits (91), Expect = 0.019 Identities = 76/369 (20%), Positives = 144/369 (39%), Gaps = 30/369 (8%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMP 612 P+P +P P+R GP + A +P P S+ P A PV Sbjct: 1688 PAPESTPIITAPTR--KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745 Query: 613 KRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGT 672 + + SPK P + S + + F P E+A+ A + P + Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKAS----TPLTAAAFEKVLPKPESASVSAAPSPPV--S 1799 Query: 673 WSSVVSGVPRLSPKTH-RPRSPRQNSIGNTPSGPVLASPQ---AGIIPTEAVAMPIPAAS 728 S VP L PK P SP + +PS P+ + + +IP E ++ +P S Sbjct: 1800 LPLAPSPVPTLPPKQQFLPSSP--GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857 Query: 729 -----PTPASPASNRAVTPSSE---AKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAEN 780 PTP S A TPS++ K+++ +S E + + T + +A+ Sbjct: 1858 VLVNMPTPKS-AGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQL 1916 Query: 781 KGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREG-EKSRDLIKDKIEPS 839 + + E + K+ +++ + + + + + Q+ R KS++++ +P Sbjct: 1917 AAAAEIDEE---PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPD 1973 Query: 840 AKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHK-RGPEVTSQGVQTSSPACKQEKDD 898 S S + G +K S + + + K +G V++ T +P ++E ++ Sbjct: 1974 VYKS--PASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEE 2031 Query: 899 KEEKKDAAE 907 +E + E Sbjct: 2032 EEVDETGVE 2040 Score = 37.7 bits (86), Expect = 0.073 Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 27/195 (13%) Query: 43 GGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPR 102 G A P P + PP P +SP S + C G S+ L GP Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVT-C-----KMGATVPQASKGLPAKKGPTA 1680 Query: 103 PFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACE-PVYGPLT- 160 VL+ P APTR P ++S A P CP P+ + GPL+ Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSS--------ATSPPICPDPSAKNGSKGPLST 1732 Query: 161 ---MSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSS 217 L P Q+ + + + + PP + A+ A P P S+ Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA----AFEKVLPKPESA 1788 Query: 218 SVSSSSATAPSSVVA 232 SVS+ APS V+ Sbjct: 1789 SVSA----APSPPVS 1799 Score = 37.4 bits (85), Expect = 0.095 Identities = 40/194 (20%), Positives = 64/194 (32%), Gaps = 18/194 (9%) Query: 49 PYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLL 108 P P P P P P+ SS ++S + GA P + P P Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615 Query: 109 LPLASPGAPPAAPTRASPLGARASPP------------------RSGVSLARPAPGCPRP 150 P +P +P P +P G SPP + G ++ + + G P Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675 Query: 151 ACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAA 210 + ++ P+ ++ Q ++ PP K G G L++ A Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735 Query: 211 APSPSSSSVSSSSA 224 AP SS +A Sbjct: 1736 APLLPVQKDSSKTA 1749 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 92.8 bits (229), Expect = 2e-18 Identities = 184/776 (23%), Positives = 275/776 (35%), Gaps = 115/776 (14%) Query: 568 QSGPNSLPPRAA--TPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSP 625 +S P + P R+A + P SRPP+ + P+ + SP PVS+ + + P + Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131 Query: 626 KAQRHPRNHRVSAG-------RGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVS 678 K R V+ G R ++S+G + P +P +AR S + GT Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT----EV 187 Query: 679 GVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAAS---PTPASPA 735 G+PR +P RPR P + P V ++ + A P+A PAS + Sbjct: 188 GLPRPAPSA-RPRPPTEG-----PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241 Query: 736 SNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSF-SKAENKGIS----PVVSEH 790 + + TP S SPA + + + +P+ S+ + KG+ P V+ Sbjct: 242 LSSSATPLS-------------SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 RK P+ S L + G K+R + + + + S Sbjct: 289 RKDA------------APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 T P SPS PS+ + P + T+ P + + QV Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSLQTIPPIQVP 392 Query: 911 KSTLNPNAKEF-NPRSFSQPKPSTTPTSPRPQA----------QPSPSMVGHQQP----- 954 S +P+ + +P + S + +T+ SP QA Q S+ +P Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452 Query: 955 -TPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRA-VPNMPQQR---QD 1009 +P P+ + +SP V PL P+T P+ + + P P Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSS-PLTIHPLQALSSLASHSPQAPLSSLIMPP 511 Query: 1010 QHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPV 1069 QS++ P+ P TPP + +A P Q + PL PH+ +P Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT---------PHLETPP 562 Query: 1070 IQGNARMMAPP---THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAIST 1126 + APP T P SS AT A A P SP +S Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATP-----PPQAPPALASPPLQGLPSPP----LSP 613 Query: 1127 GSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLAS 1186 + A P L P P P A+P + S AP+ + H QA + S Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP--SPQAPNALAVHLLQAPFSPP-PS 670 Query: 1187 PQQQSAIYHAGLAPTPPSMTPASNTQ----SPQNSFPAAQQTVFTIHPSHVQPAYTNPPH 1242 P Q+ P PS TP S +P P + + PS P PP Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730 Query: 1243 MAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFP 1298 A Q VP P A PM T PP P LA LQ +P S A P Sbjct: 731 AAPPLQ-------VPPSPPASPPMSPSATPPPRVP-PLLAAPPLQ-VPPSPPASLP 777 Score = 92.8 bits (229), Expect = 2e-18 Identities = 200/857 (23%), Positives = 293/857 (34%), Gaps = 182/857 (21%) Query: 495 PPGQRN-----REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGG 549 P GQ+ E ++ G + +P+ +G+ R TS + P+ +R G Sbjct: 128 PLGQKGLRISAEETVARGKATE-APKRSALSAGAR--RDTSGPTPGTPSPAMARRSRAAG 184 Query: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRP--------PSHPSA 601 P P+PS+RP + S+ + T PS P+ RP P+ S Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS--PAARRRPSAGGGLQRPASRSL 242 Query: 602 HGSPAPVSTMPKRMSSEGP-PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT 660 S P+S+ P R GP R +P+A HP + GL+ + PP T Sbjct: 243 SSSATPLSS-PAR---SGPSARGTPRAPAHPSQPK--------PKGLQAL--RPPQ--VT 286 Query: 661 PPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV 720 PP +P+ G SS P S RP P N+ P A + P+ + Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP---------ATLPPSPPL 337 Query: 721 AMPIPAASPTPASPASNRAV-----TPSSEAKDSRLQDQRQNSPAGNKENIKPNE----- 770 A P+P A P+P++P S + + TP S+A S Q P + + I P + Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP--SLQTIPPIQVPHSL 395 Query: 771 TSPSFSKAENK-GISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSR 829 TSPS + +S + + L+ + + P T S L + +R Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS---LTSPSRPASTPP 452 Query: 830 DLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSS 889 D S + S P SP + S+ P +T +Q S Sbjct: 453 D------------------SPPLQAPLSLPASPPLQTSLSPAVSPLSSP-LTIHPLQALS 493 Query: 890 PACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPK----PSTTP---------- 935 +S+L P + + P S + P PS P Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553 Query: 936 TSPRPQAQPSPSMVGHQ-QPTPVYTQP------VCFAPNMMYPVPVSPGVQPLYPIPMTP 988 T+P + P P+ Q P+P+ T P + P P SP +Q L P++P Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613 Query: 989 M--PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIA--ATPPAYSTQYVAYSPQ 1044 + P QA A+P + P+ A PP++ ATP + +A Sbjct: 614 LATPPPQAPPXLALPPL------------QAPPSPPASPPLSPLATPSPQAPNALAVHLL 661 Query: 1045 QFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAM 1104 Q P P P Q+ SP + +A PP+ A P L + + Sbjct: 662 QAPFSP--PPSPPVQAPFSPPASPPVSPSA---TPPSQAPPSLAAP------------PL 704 Query: 1105 YACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGS 1164 P P + SPS + A P P P P A+P S Sbjct: 705 QVPPSPPASPPMSPS--------ATPPPQAPPPLAAPPLQVPPSPPASP---PMSPSATP 753 Query: 1165 HPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQT 1224 P P+ LA+P Q + P+PP+ P S P Sbjct: 754 PPRVPPL------------LAAPPLQ-------VPPSPPASLPMSPLAKP---------- 784 Query: 1225 VFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGP---QAAL 1281 P PA PP A G P P+A PM + T PP P A L Sbjct: 785 -----PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839 Query: 1282 AQSALQPIPVSTTAHFP 1298 Q P P S T P Sbjct: 840 LQVPPSP-PASPTLQAP 855 Score = 83.2 bits (204), Expect = 2e-15 Identities = 192/809 (23%), Positives = 266/809 (32%), Gaps = 152/809 (18%) Query: 571 PNSLPPRAATPTRPPSRPPSRPS------------RPPSHPSAHGSPAPVSTMPKRMSSE 618 P L PR RPP PP P+ R P A G +T+P+ Sbjct: 22 PGLLTPRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGGIGG--ATIPESAPRA 77 Query: 619 GPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNP-PSEAATPPVARTSPSG------G 671 GP R + + R+P + ++GRG + + S P S R P G Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137 Query: 672 TWSSVVSGVPRLSPK-THRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPT 730 +V G +PK + R+++ G TP P A + V +P PA S Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197 Query: 731 PASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P P + SS ++ S + SPA + PS + S Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEP----SPAARRR--------PSAGGGLQRPAS------ 239 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPS-AKDSFIENSS 849 S S S L + R G +R + PS K ++ Sbjct: 240 ------------------RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281 Query: 850 SNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQV 909 + K +P++ P ++S + T SP+ K D A Sbjct: 282 PPQVTPPRKDAAPALGP-------------LSSSPLATPSPS--GTKARPVPPPDNAATP 326 Query: 910 RKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMM 969 +TL P+ P + P PS P+ Q PSP Q P T P AP + Sbjct: 327 LPATLPPSPPLATPLPLAPPSPSAPPSL---QTLPSPPATPPSQAPPSMTTPPMQAPPSL 383 Query: 970 YPVP--------VSPGVQ-PLYPIPMTPMPVNQAKTYRAVPNMP--------QQRQDQHH 1012 +P SP +Q P P+ ++ + QA T P + RQ Q Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLALSSL---QATTSLGSPTLQATHSFLTMSPRQTQAS 440 Query: 1013 QSAMMHPASAA--GPP------IAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPH 1064 ++ PAS PP + A+PP ++ A SP + PL H P Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL---SSPLTIH-PLQALSSLA 496 Query: 1065 VYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKL---PYNKETSPSFY 1121 +SP ++ +M PP Q L S A T + P L P ++P Sbjct: 497 SHSPQAPLSSLIM-PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555 Query: 1122 FAISTGSL-----AQQYAHPNATLHPHTPH----PQPSATPTGQQQSQHGGSHPAPSPVQ 1172 + T Q P T P TP P P A P G P SP+ Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615 Query: 1173 HHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAA-----QQTVFT 1227 QA L L Q P+PP+ P S +P P A Q F+ Sbjct: 616 TPPPQAPPXLALPPLQ---------APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666 Query: 1228 IHPSHVQPAYTNPPHMAHV-----------PQAHVQSGMVPSHPTAHAPMMLMTTQPPGG 1276 PS A +PP V P VP P A PM T PP Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726 Query: 1277 PQAALAQSALQ--PIPVSTTAHFPYMTHP 1303 P LA LQ P P ++ P T P Sbjct: 727 P-PPLAAPPLQVPPSPPASPPMSPSATPP 754 Score = 68.6 bits (166), Expect = 4e-11 Identities = 182/787 (23%), Positives = 259/787 (32%), Gaps = 127/787 (16%) Query: 512 NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCP-------SPSSRP- 563 +SP P + P R+ +H S P R P P SP + P Sbjct: 250 SSPARSGPSARGTP-RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 564 PSRYQSGPNSLPPRAATP---TRPPSRP-----PSRPSRPPSHPSAHGSPAPVSTMPKRM 615 PS ++ P P AATP T PPS P P P P + PS P+P +T P Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP--- 365 Query: 616 SSEGPPRMSPKAQRHPRNHR----VSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGG 671 S+ PP M+ + P + + + S L+ PPS A + T+ G Sbjct: 366 -SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA----PPSPLALSSLQATTSLGS 420 Query: 672 TWSSVVSGVPRLSPKTHR-------------PRSPRQNSIGNTPSGPVLA---SPQAGII 715 +SP+ + P SP + + P+ P L SP + Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480 Query: 716 PTEAVAMPIPA----ASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNET 771 + P+ A AS +P +P S+ + P E + S Q PA P E Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSS-LIMPPLETQSSLAPPSLQTPPASL--TTPPLEN 537 Query: 772 SPSFSKAENKGIS-PVVSEHRKQID-----DLKKFKNDFRLQPSSTSESM--------DQ 817 PS + + S P+ + H + L+ + P T S+ Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597 Query: 818 LLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRG 877 L + +G S L P + + + S P SP +SP + + Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXL--ALPPLQAPPSPPASPPLSPLATPSPQAPNA 655 Query: 878 PEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTS 937 V S P + + +P A P S S PS P S Sbjct: 656 LAVHLLQAPFSPPPSPPVQ---------------APFSPPASP--PVSPSATPPSQAPPS 698 Query: 938 ---PRPQAQPSPSMVGHQQPT---PVYTQPVCFAPNMMYP--VPVSPGVQPLYPIPMTPM 989 P Q PSP P+ P P AP + P P SP + P P Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758 Query: 990 PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQ 1049 P+ A + P+ P S + P A PP ATPP Q + P FP Q Sbjct: 759 PLLAAPPLQVPPSPPASLP----MSPLAKPPPQA-PPALATPP---LQALPSPPASFPGQ 810 Query: 1050 PLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPK 1109 P + +P Q + AP P +S Q T Sbjct: 811 --APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG------ 862 Query: 1110 LPYNKETSPSFYFAISTGSLAQQYAHPNATLH-PHTPHPQPSATPT-----GQQQSQHGG 1163 P + P A++ G P++TL P SAT T G GG Sbjct: 863 -PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921 Query: 1164 SHPAPSPVQHHQ--HQAAQALHLASPQQQSAIYHAGLAPTPPSMTPAS--------NTQS 1213 + +P P H AA + A P A L P PP+ P S T+ Sbjct: 922 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-PWPPATGPGSADGLCTIYETEG 980 Query: 1214 PQNSFPA 1220 P+++ PA Sbjct: 981 PESATPA 987 Score = 59.3 bits (142), Expect = 2e-08 Identities = 64/233 (27%), Positives = 83/233 (35%), Gaps = 21/233 (9%) Query: 4 AAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGP- 62 A AP+ A++ +RR + PG S R G P P PSA P PP GP Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206 Query: 63 ----PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASP--GA 116 S S+ + GGG RP SR L PL+SP Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA----------TPLSSPARSG 256 Query: 117 PPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQ 176 P A T +P P+ +L P PR P GPL+ S + Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS---PLATPSPSGTK 313 Query: 177 QQQQQQQQQQQQPPPAAANVRKPGGSGL-LASPAAAPSPSSSSVSSSSATAPS 228 + P PA P + L LA P+ + PS ++ S AT PS Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366 Score = 58.2 bits (139), Expect = 5e-08 Identities = 62/201 (30%), Positives = 77/201 (38%), Gaps = 24/201 (11%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSS----PPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPR 102 P P P APP P PPP SS PP A S G P S L P Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP--LATPPPQA 621 Query: 103 PFVVLLLPLASPGAPPAAPTRASPLGARASP-PRSGVSLA----------RPAPGCPRPA 151 P + L PL +P +PPA+P PL A+P P++ +LA P+P P Sbjct: 622 PPXLALPPLQAPPSPPASP----PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677 Query: 152 CEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASP--A 209 P P++ S P Q Q PP + + P LA+P Sbjct: 678 SPPASPPVSPSATP-PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736 Query: 210 AAPSPSSSSVSSSSATAPSSV 230 PSP +S S SAT P V Sbjct: 737 VPPSPPASPPMSPSATPPPRV 757 Score = 48.9 bits (115), Expect = 3e-05 Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 49/229 (21%) Query: 45 AAPGPYPSAAPPPPGPGP--------PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLG 96 A+P PSA PPP P P PPS +SPP + P R Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA-----------TPPPRVPPL 760 Query: 97 LGGPP------RPFVVLLLPLAS--PGAPPAAPTRASPLGARASPPRS---------GVS 139 L PP P + + PLA P APPA T PL A SPP S S Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT--PPLQALPSPPASFPGQAPFSPSAS 818 Query: 140 LARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKP 199 L P P PV + + P Q ++ PP Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-----------PPTPGPDTSV 867 Query: 200 GGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNS 248 G L + A P P S SS+ + P ++S P RG +S Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916 Score = 48.5 bits (114), Expect = 4e-05 Identities = 70/258 (27%), Positives = 96/258 (37%), Gaps = 65/258 (25%) Query: 7 APRSPAVATES--RRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPP-------- 56 +PR P T + R AA G + L A R+G GG P P A P Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPL---AERAGGIGGATIPESAPRAGPTRSAGTSSR 88 Query: 57 -----PPGPG----PPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL---------- 97 PP G PP++ +SP S S G G RPG GL Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVS----SPGRASGTTRPGPLGQKGLRISAEETVAR 144 Query: 98 ----GGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGC-PRPAC 152 P R + + G P P+ A +RA+ + V L RPAP PRP Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA--GTEVGLPRPAPSARPRP-- 200 Query: 153 EPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAA-A 211 P GP ++ + +P PAA R+P G L PA+ + Sbjct: 201 -PTEGP----------------RKSVSSASEHSTTEPSPAAR--RRPSAGGGLQRPASRS 241 Query: 212 PSPSSSSVSSSSATAPSS 229 S S++ +SS + + PS+ Sbjct: 242 LSSSATPLSSPARSGPSA 259 Score = 43.5 bits (101), Expect = 0.001 Identities = 64/262 (24%), Positives = 93/262 (35%), Gaps = 67/262 (25%) Query: 3 SAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPY---PSAAPPPPG 59 SA PR+PA ++ + G ++L+ P R A GP P A P P G Sbjct: 258 SARGTPRAPAHPSQPKP------KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311 Query: 60 ----PGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLA--S 113 P PPP ++P A+ PP P + LPLA S Sbjct: 312 TKARPVPPPDNAATPLPATL------------------------PPSPPLATPLPLAPPS 347 Query: 114 PGAPPAAPTRASPLGARASPP-RSGVSLARPAPGCP----------------RPACEPVY 156 P APP+ T SP A+PP ++ S+ P P P+ + Sbjct: 348 PSAPPSLQTLPSP---PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404 Query: 157 GPLTMSL--------KPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASP 208 PL +S P Q +Q Q PA+ P L+ P Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464 Query: 209 AAAPSPSSSSVSSSSATAPSSV 230 A+ P +S S + S ++P ++ Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTI 486 Score = 42.0 bits (97), Expect = 0.004 Identities = 65/252 (25%), Positives = 83/252 (32%), Gaps = 53/252 (21%) Query: 45 AAPGPYPSAAPPPPGP----GPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGP 100 A+P PSA PP P PP SPP++ S P + L P Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-------ATPPPQAPPPLAAP 733 Query: 101 PRPFVVLLLPLASPGAPPAAPT-----------RASPLGARASPPRS--GVSLARPAPGC 147 P L +P + P +PP +P+ A PL SPP S LA+P P Sbjct: 734 P-----LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788 Query: 148 PRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANV---------RK 198 P P PL P Q PPP A V Sbjct: 789 PPALATP---PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845 Query: 199 PGGSGLLASPAAAPSPS-SSSVSSSSAT---------APSSVVAATSGGGRPGLGRGRNS 248 P S L +P P+P +SVS T PS ++T G P L +S Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSS 903 Query: 249 NKGLPQSTISFD 260 P+ +D Sbjct: 904 ATSTPEELRGYD 915 Score = 40.8 bits (94), Expect = 0.009 Identities = 51/189 (26%), Positives = 69/189 (36%), Gaps = 33/189 (17%) Query: 46 APGPYPSA-APPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPF 104 +P P P AP P PP S ++PPS + P S L PP Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQA--------------PPS-----LAAPP--- 703 Query: 105 VVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARP-----APGCPRPACEPVYGPL 159 L +P + P +PP +P+ P +A PP + L P +P A P P Sbjct: 704 --LQVPPSPPASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759 Query: 160 TMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAP-SPSSSS 218 ++ P Q + Q PP A + S + P AP SPS+S Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819 Query: 219 VSSSSATAP 227 S AT P Sbjct: 820 PMSPLATPP 828 Score = 39.7 bits (91), Expect = 0.019 Identities = 49/187 (26%), Positives = 62/187 (33%), Gaps = 34/187 (18%) Query: 63 PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLP---LASPGAPPA 119 PPS Q+ P S + P L L PP L L +P P Sbjct: 520 PPSLQTPPASLTT-------------PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566 Query: 120 APTRASPLGARASPPRSGVSLARPAP------------GCPRP-----ACEPVYGPLTMS 162 P +A P PP + S+A P P G P P A P P ++ Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626 Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAP-SPSSSSVSS 221 L P Q Q P A ++ + S + P AP SP +S S Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686 Query: 222 SSATAPS 228 SAT PS Sbjct: 687 PSATPPS 693 Score = 37.0 bits (84), Expect = 0.12 Identities = 49/174 (28%), Positives = 57/174 (32%), Gaps = 24/174 (13%) Query: 4 AAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPP 63 A P++P V P +LQ P R G + GP + A PGP PP Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA-LAPGPPPP 883 Query: 64 PSRQ-----------------SSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVV 106 PSR +S P + S GG A P L P Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943 Query: 107 LLLPLA---SPGAP---PAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEP 154 PLA +PGAP P A S G G A PAPG P P Sbjct: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997 Score = 36.2 bits (82), Expect = 0.21 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 11/162 (6%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP-APVSTM 611 P P P P SR PS SGP+ L +++ T P S P +A P A ++ Sbjct: 878 PGP-PPPPSRSPSSTLSGPD-LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935 Query: 612 PKRMSSEGP--PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSP- 668 S GP P A P + G GS + GL + E+ATP P Sbjct: 936 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS-ADGLCTIYETEGPESATPAPGALDPG 994 Query: 669 -SGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLAS 709 S GT + + RSP+Q +G P G + AS Sbjct: 995 PSPGTSGGKAAAGAGAGASS---RSPKQARLGELPLGALQAS 1033 Score = 35.0 bits (79), Expect = 0.47 Identities = 60/240 (25%), Positives = 87/240 (36%), Gaps = 63/240 (26%) Query: 38 SGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL 97 + R G P P S PPPP P+A G+ G G +P + R G+ Sbjct: 18 AARAPGLLTPRPPGSPRPPPP----------VTPAALRVLGAAGAVGR--KPLAERAGGI 65 Query: 98 GGPPRPFVVLLLPLASPGAPPAAPTRASPLGAR---ASPPRSG-VSLARPAPG-CPRPAC 152 GG P AP A PTR++ +R + PP SG A PA P P Sbjct: 66 GGATIP----------ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115 Query: 153 EPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPP--------------------PA 192 P G + + +P Q+ + ++ + + + P P+ Sbjct: 116 SP--GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173 Query: 193 AANVRKPGGSGL-----LASPAAAPSP-------SSSSVSSSSATAPSSVV--AATSGGG 238 A R+ +G +P+A P P S SS S S T PS ++GGG Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 84.3 bits (207), Expect = 7e-16 Identities = 119/475 (25%), Positives = 173/475 (36%), Gaps = 79/475 (16%) Query: 838 PSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNT-EHKRGPEVTSQGVQTSSPACKQEK 896 PSA + +S + S+K S + SN + ++ T + +TSS K ++ Sbjct: 60 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 119 Query: 897 DDKEEKKDAAEQVRKSTLNPNAK-EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPT 955 + E + + N + +P+ Q ST+P+ P PQ S S QQ Sbjct: 120 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 179 Query: 956 PVYTQPVCFAPNMMYPVPVS-PGVQPLYPIP-----MTPMPVNQAKTYRAVPNMPQQRQD 1009 P AP + P P S P P P P T +P + T PN PQ Sbjct: 180 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ---- 235 Query: 1010 QHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPV 1069 A T P T ++ +P P +P H P + S HP + Sbjct: 236 ------------------APTAPVPHT-HIQQAPALHPQRPPSPHPPPHPSPHPPLQP-- 274 Query: 1070 IQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSL 1129 + G+A + P+HAQP L H++ A P L + P ++ Sbjct: 275 LTGSAGQPSAPSHAQPPLHGQGP------PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 328 Query: 1130 AQQYAHPNATLHPHTPHPQPSATPT--GQQQSQHGGSHPAPSPVQH---------HQHQA 1178 A P A +PHT P++ QQ + PAP + H Q A Sbjct: 329 APLGTSP-AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 387 Query: 1179 AQA----LHLASPQQQSAIYHAGLAPTPPSMTPAS--NTQSPQNSFPAAQQTVFTIHPSH 1232 QA HL+ P S +A L P PP++ P S +T P ++ P Q + P Sbjct: 388 PQAHKHPPHLSGPSPFS--MNANL-PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 444 Query: 1233 VQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQP----------PGGP 1277 PA PP + QS +P P +H P L P PGGP Sbjct: 445 SSPA--QPPGL-------TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490 Score = 67.8 bits (164), Expect = 7e-11 Identities = 127/532 (23%), Positives = 187/532 (35%), Gaps = 96/532 (18%) Query: 741 TPSSEAKDSRLQDQRQNSPAGNKENIKP-NETSPSFSKAENKGISPVVSEHRKQIDDLKK 799 T S S L+ R+ PA P NE S + N + S + + + +KK Sbjct: 20 TRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGR--NSPSAASTSSNDSKAETVKK 77 Query: 800 FKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP 859 + + SS +S NK + ++K+ +++ +S T S+P Sbjct: 78 SAKKVKEEASSPLKS-----NKRQ---------REKVASDTEEADRTSSKKTKTQEISRP 123 Query: 860 NSPS-----ISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKST- 913 NSPS S S N E P+ Q +++SP+ +D++ + +A+Q Sbjct: 124 NSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ 183 Query: 914 ---------LNPNAKEFNPRSFSQPKPSTTP--TSPRPQAQPSPSMVGHQQPTPVYTQP- 961 + P P + P P TP T+ PQ P+ S +Q P P Sbjct: 184 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 243 Query: 962 --VCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRA-VPNMPQQRQDQHHQSA--- 1015 + AP + P SP P +P P P+ Q T A P+ P Q H Sbjct: 244 THIQQAPALHPQRPPSPHPPP-HPSPHPPL---QPLTGSAGQPSAPSHAQPPLHGQGPPG 299 Query: 1016 ---------MMHP-----------ASAAGPPIAATP----PAYSTQYVA-YSPQQFPNQP 1050 + HP AS P+ +P P S Q A S Q P Sbjct: 300 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359 Query: 1051 LVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYA-CPK 1109 Q +P PH+ P ++ AP H P +S + +M A P Sbjct: 360 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS--------PFSMNANLPP 411 Query: 1110 LPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPS 1169 P K S ++ST + P + P P A P G QSQ+ PA Sbjct: 412 PPALKPLS-----SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 466 Query: 1170 PVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAA 1221 P LH +PQ A H + PP +TP + P S P A Sbjct: 467 P--------PTGLHQVAPQPPFA-QHPFVPGGPPPITPPT---CPSTSTPPA 506 Score = 66.6 bits (161), Expect = 1e-10 Identities = 82/344 (23%), Positives = 128/344 (37%), Gaps = 22/344 (6%) Query: 437 REARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPP 496 R + N + SS KA ++ + +EE + ++ N +RE + +T E Sbjct: 53 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 112 Query: 497 GQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNS-GSDQRVVNGGVPWPSP 555 + + IS R NSP G+ S SRS + +P D R + +P SP Sbjct: 113 KKTKTQEIS----RPNSPSEGEGESSD--SRSVNDEGSSDPKDIDQDNRSTSPSIP--SP 164 Query: 556 CPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 + S S Q + PP PT P S P P P+ +P+ + P+ Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS 224 Query: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 + P+A P H ++ H PP + PP+ + S G Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ--- 281 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL---ASPQAGIIPTEAVAMPIP-AASPTP 731 S P H P +S+ +GP+L PQ +P +A P SP Sbjct: 282 -PSAPSHAQPPLHGQGPPGPHSL---QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337 Query: 732 ASPASNRAVTPSSEAKDSRLQDQRQNSPAG--NKENIKPNETSP 773 A P ++ + S A S+ + Q P +IKP T+P Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381 Score = 50.4 bits (119), Expect = 1e-05 Identities = 117/584 (20%), Positives = 195/584 (33%), Gaps = 111/584 (19%) Query: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP--SHPSAHGSPAP 607 +P P PS ++PP QS +LPP A + PP+ +PP HP G P P Sbjct: 437 MPQSQPLPSSPAQPPGLTQS--QNLPPPPA--SHPPTGLHQVAPQPPFAQHPFVPGGPPP 492 Query: 608 VSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSG---------LEFVSHNPPSEA 658 ++ P S P P P +A GSI+ G ++ + + E Sbjct: 493 IT--PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550 Query: 659 ATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTE 718 +PP SPS V P + ++ R + + P AG + Sbjct: 551 ESPPPPPRSPSP---EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAK 607 Query: 719 AVAMPIPAASPTPASPA-----------------------SNRAVTPSSEAKDSRLQDQR 755 I A A + RA SS A + RL D + Sbjct: 608 KREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 667 Query: 756 QNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESM 815 + P + + +P T+ + + P + + L ++ + P++ + Sbjct: 668 LSGPGHMRPSFEPPPTTIA-------AVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720 Query: 816 DQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHK 875 LN ++ P ++ P+I + Sbjct: 721 YMPLN----------------------------PTDPLLAYHMPGLYNVDPTIRERELRE 752 Query: 876 RGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNP-RSFSQPKPSTT 934 R E+ + + +E++ +E K E V+ L+P NP F++ T Sbjct: 753 R--EIREREI--------RERELRERMKPGFE-VKPPELDPLHPAANPMEHFARHSALTI 801 Query: 935 PTSPRPQAQPSPSMVGHQQPTPVYTQPVCFA-----PNMMYPVPV-SPGVQPLYPIPMTP 988 P P A P P H P+ + + A P M YP + + + +T Sbjct: 802 P----PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTS 857 Query: 989 MPVNQAKTYRAVPNMPQQRQDQH----HQSAMMHPASAAGPPIAATPPAYSTQYVA---Y 1041 P+ + + + P+ Q HQ +H S AGP P + ++A Y Sbjct: 858 DPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS-AGPVHPLVDPLTAGPHLARFPY 916 Query: 1042 SPQQFPNQPLVQHVPHYQS--QHPHVYSPVIQGNARMMAPPTHA 1083 P PN PL+ PH +HP +P + + PP A Sbjct: 917 PPGTLPN-PLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 959 Score = 45.8 bits (107), Expect = 3e-04 Identities = 64/240 (26%), Positives = 78/240 (32%), Gaps = 46/240 (19%) Query: 43 GGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRP-------GSRRLL 95 G PGP+ A P PP PP AS G A P S+ L Sbjct: 294 GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 353 Query: 96 GLGGPPRPFVVLLLPLASPGA--PPAAPTRASPLG-ARASPPRSGVSLARPAPGC----- 147 PPR + PLA P PP P P A PP L+ P+P Sbjct: 354 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH----LSGPSPFSMNANL 409 Query: 148 -PRPACEPVYG----------PLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPP------ 190 P PA +P+ P + L PQ Q Q Q Q PP Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469 Query: 191 ---------PAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPG 241 P A + PGG + +P PS S+ ++ P AA SGG G Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 528 Score = 43.9 bits (102), Expect = 0.001 Identities = 51/182 (28%), Positives = 64/182 (35%), Gaps = 23/182 (12%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFV- 105 PGP PSA PP P S+ + P A + + A +R PP P Sbjct: 210 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269 Query: 106 VLLLPLASPGAPPAAPTRASPLGARASPP-----RSGVSLARPAPGCP---RPACEPVYG 157 L PL P+AP+ A P PP ++G L P P P P Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 329 Query: 158 PLTMS---LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 PL S P Q Q Q QQ ++Q PPA LA P P P Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-----------LAMPHIKPPP 378 Query: 215 SS 216 ++ Sbjct: 379 TT 380 Score = 33.1 bits (74), Expect = 1.8 Identities = 41/181 (22%), Positives = 61/181 (33%), Gaps = 33/181 (18%) Query: 1165 HPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAP--------TPPSMTPA-------- 1208 HPA +P++H +A + + A +H GL P P + P Sbjct: 784 HPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLA 843 Query: 1209 -----SNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAH 1263 + + S P A+ +F + P H Q ++ + H Q P HP Sbjct: 844 AERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVD 903 Query: 1264 ----APMMLMTTQPPGG-PQAALAQ----SALQPIPVSTTAH---FPYMTHPSVQAHHQQ 1311 P + PPG P L Q + PV T + P P + A HQ Sbjct: 904 PLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQL 963 Query: 1312 Q 1312 Q Sbjct: 964 Q 964 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/153 (22%), Positives = 61/153 (39%), Gaps = 29/153 (18%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVV 106 P PS + PP GPG + PP C G+ +GG + G P P V Sbjct: 495 PPTCPSTSTPPAGPGT----SAQPP----CSGAAASGGS--------IAGGSSCPLPTVQ 538 Query: 107 L----LLPLASPGAPPAAPTRASPLGARASPP-------RSGVSLARPAPGCPRPACEPV 155 + L P +PP P SP P R L R C R + Sbjct: 539 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR--TDLY 596 Query: 156 YGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 + PL S +++++ ++ +++ +Q+ +++++ Sbjct: 597 FMPLAGSKLAKKREEAIEKAKREAEQKAREERE 629 Score = 30.8 bits (68), Expect = 8.9 Identities = 29/112 (25%), Positives = 38/112 (33%), Gaps = 10/112 (8%) Query: 103 PFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMS 162 P V P ++P P PT A A PP+ G A AP P+ PV Sbjct: 190 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ-GSPTASQAPNQPQAPTAPV------- 241 Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 P QQ Q+ P P G +G ++P+ A P Sbjct: 242 --PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 291 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 84.3 bits (207), Expect = 7e-16 Identities = 119/475 (25%), Positives = 173/475 (36%), Gaps = 79/475 (16%) Query: 838 PSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNT-EHKRGPEVTSQGVQTSSPACKQEK 896 PSA + +S + S+K S + SN + ++ T + +TSS K ++ Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 673 Query: 897 DDKEEKKDAAEQVRKSTLNPNAK-EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPT 955 + E + + N + +P+ Q ST+P+ P PQ S S QQ Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733 Query: 956 PVYTQPVCFAPNMMYPVPVS-PGVQPLYPIP-----MTPMPVNQAKTYRAVPNMPQQRQD 1009 P AP + P P S P P P P T +P + T PN PQ Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ---- 789 Query: 1010 QHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPV 1069 A T P T ++ +P P +P H P + S HP + Sbjct: 790 ------------------APTAPVPHT-HIQQAPALHPQRPPSPHPPPHPSPHPPLQP-- 828 Query: 1070 IQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSL 1129 + G+A + P+HAQP L H++ A P L + P ++ Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGP------PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882 Query: 1130 AQQYAHPNATLHPHTPHPQPSATPT--GQQQSQHGGSHPAPSPVQH---------HQHQA 1178 A P A +PHT P++ QQ + PAP + H Q A Sbjct: 883 APLGTSP-AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 941 Query: 1179 AQA----LHLASPQQQSAIYHAGLAPTPPSMTPAS--NTQSPQNSFPAAQQTVFTIHPSH 1232 QA HL+ P S +A L P PP++ P S +T P ++ P Q + P Sbjct: 942 PQAHKHPPHLSGPSPFS--MNANL-PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 998 Query: 1233 VQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQP----------PGGP 1277 PA PP + QS +P P +H P L P PGGP Sbjct: 999 SSPA--QPPGL-------TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044 Score = 67.8 bits (164), Expect = 7e-11 Identities = 127/532 (23%), Positives = 187/532 (35%), Gaps = 96/532 (18%) Query: 741 TPSSEAKDSRLQDQRQNSPAGNKENIKP-NETSPSFSKAENKGISPVVSEHRKQIDDLKK 799 T S S L+ R+ PA P NE S + N + S + + + +KK Sbjct: 574 TRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGR--NSPSAASTSSNDSKAETVKK 631 Query: 800 FKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP 859 + + SS +S NK + ++K+ +++ +S T S+P Sbjct: 632 SAKKVKEEASSPLKS-----NKRQ---------REKVASDTEEADRTSSKKTKTQEISRP 677 Query: 860 NSPS-----ISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKST- 913 NSPS S S N E P+ Q +++SP+ +D++ + +A+Q Sbjct: 678 NSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ 737 Query: 914 ---------LNPNAKEFNPRSFSQPKPSTTP--TSPRPQAQPSPSMVGHQQPTPVYTQP- 961 + P P + P P TP T+ PQ P+ S +Q P P Sbjct: 738 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 797 Query: 962 --VCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRA-VPNMPQQRQDQHHQSA--- 1015 + AP + P SP P +P P P+ Q T A P+ P Q H Sbjct: 798 THIQQAPALHPQRPPSPHPPP-HPSPHPPL---QPLTGSAGQPSAPSHAQPPLHGQGPPG 853 Query: 1016 ---------MMHP-----------ASAAGPPIAATP----PAYSTQYVA-YSPQQFPNQP 1050 + HP AS P+ +P P S Q A S Q P Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913 Query: 1051 LVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYA-CPK 1109 Q +P PH+ P ++ AP H P +S + +M A P Sbjct: 914 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS--------PFSMNANLPP 965 Query: 1110 LPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPS 1169 P K S ++ST + P + P P A P G QSQ+ PA Sbjct: 966 PPALKPLS-----SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 1020 Query: 1170 PVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAA 1221 P LH +PQ A H + PP +TP + P S P A Sbjct: 1021 P--------PTGLHQVAPQPPFA-QHPFVPGGPPPITPPT---CPSTSTPPA 1060 Score = 66.6 bits (161), Expect = 1e-10 Identities = 82/344 (23%), Positives = 128/344 (37%), Gaps = 22/344 (6%) Query: 437 REARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPP 496 R + N + SS KA ++ + +EE + ++ N +RE + +T E Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 666 Query: 497 GQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNS-GSDQRVVNGGVPWPSP 555 + + IS R NSP G+ S SRS + +P D R + +P SP Sbjct: 667 KKTKTQEIS----RPNSPSEGEGESSD--SRSVNDEGSSDPKDIDQDNRSTSPSIP--SP 718 Query: 556 CPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 + S S Q + PP PT P S P P P+ +P+ + P+ Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS 778 Query: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 + P+A P H ++ H PP + PP+ + S G Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ--- 835 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL---ASPQAGIIPTEAVAMPIP-AASPTP 731 S P H P +S+ +GP+L PQ +P +A P SP Sbjct: 836 -PSAPSHAQPPLHGQGPPGPHSL---QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891 Query: 732 ASPASNRAVTPSSEAKDSRLQDQRQNSPAG--NKENIKPNETSP 773 A P ++ + S A S+ + Q P +IKP T+P Sbjct: 892 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Score = 50.4 bits (119), Expect = 1e-05 Identities = 117/584 (20%), Positives = 195/584 (33%), Gaps = 111/584 (19%) Query: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP--SHPSAHGSPAP 607 +P P PS ++PP QS +LPP A + PP+ +PP HP G P P Sbjct: 991 MPQSQPLPSSPAQPPGLTQS--QNLPPPPA--SHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046 Query: 608 VSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSG---------LEFVSHNPPSEA 658 ++ P S P P P +A GSI+ G ++ + + E Sbjct: 1047 IT--PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104 Query: 659 ATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTE 718 +PP SPS V P + ++ R + + P AG + Sbjct: 1105 ESPPPPPRSPSP---EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAK 1161 Query: 719 AVAMPIPAASPTPASPA-----------------------SNRAVTPSSEAKDSRLQDQR 755 I A A + RA SS A + RL D + Sbjct: 1162 KREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 1221 Query: 756 QNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESM 815 + P + + +P T+ + + P + + L ++ + P++ + Sbjct: 1222 LSGPGHMRPSFEPPPTTIA-------AVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274 Query: 816 DQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHK 875 LN ++ P ++ P+I + Sbjct: 1275 YMPLN----------------------------PTDPLLAYHMPGLYNVDPTIRERELRE 1306 Query: 876 RGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNP-RSFSQPKPSTT 934 R E+ + + +E++ +E K E V+ L+P NP F++ T Sbjct: 1307 R--EIREREI--------RERELRERMKPGFE-VKPPELDPLHPAANPMEHFARHSALTI 1355 Query: 935 PTSPRPQAQPSPSMVGHQQPTPVYTQPVCFA-----PNMMYPVPV-SPGVQPLYPIPMTP 988 P P A P P H P+ + + A P M YP + + + +T Sbjct: 1356 P----PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTS 1411 Query: 989 MPVNQAKTYRAVPNMPQQRQDQH----HQSAMMHPASAAGPPIAATPPAYSTQYVA---Y 1041 P+ + + + P+ Q HQ +H S AGP P + ++A Y Sbjct: 1412 DPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS-AGPVHPLVDPLTAGPHLARFPY 1470 Query: 1042 SPQQFPNQPLVQHVPHYQS--QHPHVYSPVIQGNARMMAPPTHA 1083 P PN PL+ PH +HP +P + + PP A Sbjct: 1471 PPGTLPN-PLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 1513 Score = 45.8 bits (107), Expect = 3e-04 Identities = 64/240 (26%), Positives = 78/240 (32%), Gaps = 46/240 (19%) Query: 43 GGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRP-------GSRRLL 95 G PGP+ A P PP PP AS G A P S+ L Sbjct: 848 GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 907 Query: 96 GLGGPPRPFVVLLLPLASPGA--PPAAPTRASPLG-ARASPPRSGVSLARPAPGC----- 147 PPR + PLA P PP P P A PP L+ P+P Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH----LSGPSPFSMNANL 963 Query: 148 -PRPACEPVYG----------PLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPP------ 190 P PA +P+ P + L PQ Q Q Q Q PP Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023 Query: 191 ---------PAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPG 241 P A + PGG + +P PS S+ ++ P AA SGG G Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 1082 Score = 43.9 bits (102), Expect = 0.001 Identities = 51/182 (28%), Positives = 64/182 (35%), Gaps = 23/182 (12%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFV- 105 PGP PSA PP P S+ + P A + + A +R PP P Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 823 Query: 106 VLLLPLASPGAPPAAPTRASPLGARASPP-----RSGVSLARPAPGCP---RPACEPVYG 157 L PL P+AP+ A P PP ++G L P P P P Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883 Query: 158 PLTMS---LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 PL S P Q Q Q QQ ++Q PPA LA P P P Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-----------LAMPHIKPPP 932 Query: 215 SS 216 ++ Sbjct: 933 TT 934 Score = 33.1 bits (74), Expect = 1.8 Identities = 41/181 (22%), Positives = 61/181 (33%), Gaps = 33/181 (18%) Query: 1165 HPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAP--------TPPSMTPA-------- 1208 HPA +P++H +A + + A +H GL P P + P Sbjct: 1338 HPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLA 1397 Query: 1209 -----SNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAH 1263 + + S P A+ +F + P H Q ++ + H Q P HP Sbjct: 1398 AERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVD 1457 Query: 1264 ----APMMLMTTQPPGG-PQAALAQ----SALQPIPVSTTAH---FPYMTHPSVQAHHQQ 1311 P + PPG P L Q + PV T + P P + A HQ Sbjct: 1458 PLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQL 1517 Query: 1312 Q 1312 Q Sbjct: 1518 Q 1518 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/153 (22%), Positives = 61/153 (39%), Gaps = 29/153 (18%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVV 106 P PS + PP GPG + PP C G+ +GG + G P P V Sbjct: 1049 PPTCPSTSTPPAGPGT----SAQPP----CSGAAASGGS--------IAGGSSCPLPTVQ 1092 Query: 107 L----LLPLASPGAPPAAPTRASPLGARASPP-------RSGVSLARPAPGCPRPACEPV 155 + L P +PP P SP P R L R C R + Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR--TDLY 1150 Query: 156 YGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 + PL S +++++ ++ +++ +Q+ +++++ Sbjct: 1151 FMPLAGSKLAKKREEAIEKAKREAEQKAREERE 1183 Score = 30.8 bits (68), Expect = 8.9 Identities = 29/112 (25%), Positives = 38/112 (33%), Gaps = 10/112 (8%) Query: 103 PFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMS 162 P V P ++P P PT A A PP+ G A AP P+ PV Sbjct: 744 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ-GSPTASQAPNQPQAPTAPV------- 795 Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 P QQ Q+ P P G +G ++P+ A P Sbjct: 796 --PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 845 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 84.3 bits (207), Expect = 7e-16 Identities = 119/475 (25%), Positives = 173/475 (36%), Gaps = 79/475 (16%) Query: 838 PSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNT-EHKRGPEVTSQGVQTSSPACKQEK 896 PSA + +S + S+K S + SN + ++ T + +TSS K ++ Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 673 Query: 897 DDKEEKKDAAEQVRKSTLNPNAK-EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPT 955 + E + + N + +P+ Q ST+P+ P PQ S S QQ Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733 Query: 956 PVYTQPVCFAPNMMYPVPVS-PGVQPLYPIP-----MTPMPVNQAKTYRAVPNMPQQRQD 1009 P AP + P P S P P P P T +P + T PN PQ Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ---- 789 Query: 1010 QHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPV 1069 A T P T ++ +P P +P H P + S HP + Sbjct: 790 ------------------APTAPVPHT-HIQQAPALHPQRPPSPHPPPHPSPHPPLQP-- 828 Query: 1070 IQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSL 1129 + G+A + P+HAQP L H++ A P L + P ++ Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGP------PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882 Query: 1130 AQQYAHPNATLHPHTPHPQPSATPT--GQQQSQHGGSHPAPSPVQH---------HQHQA 1178 A P A +PHT P++ QQ + PAP + H Q A Sbjct: 883 APLGTSP-AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 941 Query: 1179 AQA----LHLASPQQQSAIYHAGLAPTPPSMTPAS--NTQSPQNSFPAAQQTVFTIHPSH 1232 QA HL+ P S +A L P PP++ P S +T P ++ P Q + P Sbjct: 942 PQAHKHPPHLSGPSPFS--MNANL-PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 998 Query: 1233 VQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQP----------PGGP 1277 PA PP + QS +P P +H P L P PGGP Sbjct: 999 SSPA--QPPGL-------TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044 Score = 67.8 bits (164), Expect = 7e-11 Identities = 127/532 (23%), Positives = 187/532 (35%), Gaps = 96/532 (18%) Query: 741 TPSSEAKDSRLQDQRQNSPAGNKENIKP-NETSPSFSKAENKGISPVVSEHRKQIDDLKK 799 T S S L+ R+ PA P NE S + N + S + + + +KK Sbjct: 574 TRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGR--NSPSAASTSSNDSKAETVKK 631 Query: 800 FKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP 859 + + SS +S NK + ++K+ +++ +S T S+P Sbjct: 632 SAKKVKEEASSPLKS-----NKRQ---------REKVASDTEEADRTSSKKTKTQEISRP 677 Query: 860 NSPS-----ISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKST- 913 NSPS S S N E P+ Q +++SP+ +D++ + +A+Q Sbjct: 678 NSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ 737 Query: 914 ---------LNPNAKEFNPRSFSQPKPSTTP--TSPRPQAQPSPSMVGHQQPTPVYTQP- 961 + P P + P P TP T+ PQ P+ S +Q P P Sbjct: 738 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 797 Query: 962 --VCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRA-VPNMPQQRQDQHHQSA--- 1015 + AP + P SP P +P P P+ Q T A P+ P Q H Sbjct: 798 THIQQAPALHPQRPPSPHPPP-HPSPHPPL---QPLTGSAGQPSAPSHAQPPLHGQGPPG 853 Query: 1016 ---------MMHP-----------ASAAGPPIAATP----PAYSTQYVA-YSPQQFPNQP 1050 + HP AS P+ +P P S Q A S Q P Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913 Query: 1051 LVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYA-CPK 1109 Q +P PH+ P ++ AP H P +S + +M A P Sbjct: 914 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS--------PFSMNANLPP 965 Query: 1110 LPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPS 1169 P K S ++ST + P + P P A P G QSQ+ PA Sbjct: 966 PPALKPLS-----SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 1020 Query: 1170 PVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAA 1221 P LH +PQ A H + PP +TP + P S P A Sbjct: 1021 P--------PTGLHQVAPQPPFA-QHPFVPGGPPPITPPT---CPSTSTPPA 1060 Score = 66.6 bits (161), Expect = 1e-10 Identities = 82/344 (23%), Positives = 128/344 (37%), Gaps = 22/344 (6%) Query: 437 REARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPP 496 R + N + SS KA ++ + +EE + ++ N +RE + +T E Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 666 Query: 497 GQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNS-GSDQRVVNGGVPWPSP 555 + + IS R NSP G+ S SRS + +P D R + +P SP Sbjct: 667 KKTKTQEIS----RPNSPSEGEGESSD--SRSVNDEGSSDPKDIDQDNRSTSPSIP--SP 718 Query: 556 CPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 + S S Q + PP PT P S P P P+ +P+ + P+ Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS 778 Query: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 + P+A P H ++ H PP + PP+ + S G Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ--- 835 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL---ASPQAGIIPTEAVAMPIP-AASPTP 731 S P H P +S+ +GP+L PQ +P +A P SP Sbjct: 836 -PSAPSHAQPPLHGQGPPGPHSL---QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891 Query: 732 ASPASNRAVTPSSEAKDSRLQDQRQNSPAG--NKENIKPNETSP 773 A P ++ + S A S+ + Q P +IKP T+P Sbjct: 892 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Score = 50.4 bits (119), Expect = 1e-05 Identities = 117/584 (20%), Positives = 195/584 (33%), Gaps = 111/584 (19%) Query: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP--SHPSAHGSPAP 607 +P P PS ++PP QS +LPP A + PP+ +PP HP G P P Sbjct: 991 MPQSQPLPSSPAQPPGLTQS--QNLPPPPA--SHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046 Query: 608 VSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSG---------LEFVSHNPPSEA 658 ++ P S P P P +A GSI+ G ++ + + E Sbjct: 1047 IT--PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104 Query: 659 ATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTE 718 +PP SPS V P + ++ R + + P AG + Sbjct: 1105 ESPPPPPRSPSP---EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAK 1161 Query: 719 AVAMPIPAASPTPASPA-----------------------SNRAVTPSSEAKDSRLQDQR 755 I A A + RA SS A + RL D + Sbjct: 1162 KREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 1221 Query: 756 QNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESM 815 + P + + +P T+ + + P + + L ++ + P++ + Sbjct: 1222 LSGPGHMRPSFEPPPTTIA-------AVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274 Query: 816 DQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHK 875 LN ++ P ++ P+I + Sbjct: 1275 YMPLN----------------------------PTDPLLAYHMPGLYNVDPTIRERELRE 1306 Query: 876 RGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNP-RSFSQPKPSTT 934 R E+ + + +E++ +E K E V+ L+P NP F++ T Sbjct: 1307 R--EIREREI--------RERELRERMKPGFE-VKPPELDPLHPAANPMEHFARHSALTI 1355 Query: 935 PTSPRPQAQPSPSMVGHQQPTPVYTQPVCFA-----PNMMYPVPV-SPGVQPLYPIPMTP 988 P P A P P H P+ + + A P M YP + + + +T Sbjct: 1356 P----PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTS 1411 Query: 989 MPVNQAKTYRAVPNMPQQRQDQH----HQSAMMHPASAAGPPIAATPPAYSTQYVA---Y 1041 P+ + + + P+ Q HQ +H S AGP P + ++A Y Sbjct: 1412 DPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS-AGPVHPLVDPLTAGPHLARFPY 1470 Query: 1042 SPQQFPNQPLVQHVPHYQS--QHPHVYSPVIQGNARMMAPPTHA 1083 P PN PL+ PH +HP +P + + PP A Sbjct: 1471 PPGTLPN-PLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 1513 Score = 45.8 bits (107), Expect = 3e-04 Identities = 64/240 (26%), Positives = 78/240 (32%), Gaps = 46/240 (19%) Query: 43 GGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRP-------GSRRLL 95 G PGP+ A P PP PP AS G A P S+ L Sbjct: 848 GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 907 Query: 96 GLGGPPRPFVVLLLPLASPGA--PPAAPTRASPLG-ARASPPRSGVSLARPAPGC----- 147 PPR + PLA P PP P P A PP L+ P+P Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH----LSGPSPFSMNANL 963 Query: 148 -PRPACEPVYG----------PLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPP------ 190 P PA +P+ P + L PQ Q Q Q Q PP Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023 Query: 191 ---------PAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPG 241 P A + PGG + +P PS S+ ++ P AA SGG G Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 1082 Score = 43.9 bits (102), Expect = 0.001 Identities = 51/182 (28%), Positives = 64/182 (35%), Gaps = 23/182 (12%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFV- 105 PGP PSA PP P S+ + P A + + A +R PP P Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 823 Query: 106 VLLLPLASPGAPPAAPTRASPLGARASPP-----RSGVSLARPAPGCP---RPACEPVYG 157 L PL P+AP+ A P PP ++G L P P P P Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883 Query: 158 PLTMS---LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 PL S P Q Q Q QQ ++Q PPA LA P P P Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-----------LAMPHIKPPP 932 Query: 215 SS 216 ++ Sbjct: 933 TT 934 Score = 33.1 bits (74), Expect = 1.8 Identities = 41/181 (22%), Positives = 61/181 (33%), Gaps = 33/181 (18%) Query: 1165 HPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAP--------TPPSMTPA-------- 1208 HPA +P++H +A + + A +H GL P P + P Sbjct: 1338 HPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLA 1397 Query: 1209 -----SNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAH 1263 + + S P A+ +F + P H Q ++ + H Q P HP Sbjct: 1398 AERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVD 1457 Query: 1264 ----APMMLMTTQPPGG-PQAALAQ----SALQPIPVSTTAH---FPYMTHPSVQAHHQQ 1311 P + PPG P L Q + PV T + P P + A HQ Sbjct: 1458 PLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQL 1517 Query: 1312 Q 1312 Q Sbjct: 1518 Q 1518 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/153 (22%), Positives = 61/153 (39%), Gaps = 29/153 (18%) Query: 47 PGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVV 106 P PS + PP GPG + PP C G+ +GG + G P P V Sbjct: 1049 PPTCPSTSTPPAGPGT----SAQPP----CSGAAASGGS--------IAGGSSCPLPTVQ 1092 Query: 107 L----LLPLASPGAPPAAPTRASPLGARASPP-------RSGVSLARPAPGCPRPACEPV 155 + L P +PP P SP P R L R C R + Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR--TDLY 1150 Query: 156 YGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 + PL S +++++ ++ +++ +Q+ +++++ Sbjct: 1151 FMPLAGSKLAKKREEAIEKAKREAEQKAREERE 1183 Score = 30.8 bits (68), Expect = 8.9 Identities = 29/112 (25%), Positives = 38/112 (33%), Gaps = 10/112 (8%) Query: 103 PFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMS 162 P V P ++P P PT A A PP+ G A AP P+ PV Sbjct: 744 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ-GSPTASQAPNQPQAPTAPV------- 795 Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 P QQ Q+ P P G +G ++P+ A P Sbjct: 796 --PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 845 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 80.5 bits (197), Expect = 1e-14 Identities = 165/700 (23%), Positives = 246/700 (35%), Gaps = 100/700 (14%) Query: 568 QSGPNSLPPRAA--TPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSP 625 +S P + P R+A + P SRPP+ + P+ + SP PVS+ + + P + Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131 Query: 626 KAQRHPRNHRVSAG-------RGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVS 678 K R V+ G R ++S+G + P +P +AR S + GT Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT----EV 187 Query: 679 GVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAAS---PTPASPA 735 G+PR +P RPR P + P V ++ + A P+A PAS + Sbjct: 188 GLPRPAPSA-RPRPPTEG-----PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241 Query: 736 SNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSF-SKAENKGIS----PVVSEH 790 + + TP S SPA + + + +P+ S+ + KG+ P V+ Sbjct: 242 LSSSATPLS-------------SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 RK D P +T L ++ P + +SS Sbjct: 289 RK---DAAPALGPLSSSPLATPSPSAALQSQ---------------APPTLPATPHSSSL 330 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVT--SQGVQTSSPACKQEKDDKEEKKDAAEQ 908 C + P +P SPS + + P T SQ + Q + Sbjct: 331 TCQLATPLPLAPP-SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389 Query: 909 VRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 P A P P++ P S P A PSP V+ F+P Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLS--PLATPSPQA---PNALAVHLLQAPFSPPP 444 Query: 969 MYPV--PVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPP 1026 PV P SP P P+ + P +QA A P P Q S M P SA PP Sbjct: 445 SPPVQAPFSPPASP--PVSPSATPPSQAPPSLAAP--PLQVPPSPPASPPMSP-SATPPP 499 Query: 1027 IAATPPAYSTQYVAYSPQQFP---NQPLVQHVPHYQSQHP--HVYSPVIQGNARMMAPPT 1081 A P A +A P Q P P +Q +P + P +SP +A P Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559 Query: 1082 HAQPGLVSSSATQYGAHEQTHAMYACPKL-----PYNKETSPSFYFAISTGSLAQQYAHP 1136 P ++++ Q P+ P + P A++ G P Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619 Query: 1137 NATLH-PHTPHPQPSATPT-----GQQQSQHGGSHPAPSPVQHHQ--HQAAQALHLASPQ 1188 ++TL P SAT T G GG+ +P P H AA + A P Sbjct: 620 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 679 Query: 1189 QQSAIYHAGLAPTPPSMTPAS--------NTQSPQNSFPA 1220 A L P PP+ P S T+ P+++ PA Sbjct: 680 AFRGAPGAPL-PWPPATGPGSADGLCTIYETEGPESATPA 718 Score = 69.7 bits (169), Expect = 2e-11 Identities = 115/458 (25%), Positives = 164/458 (35%), Gaps = 81/458 (17%) Query: 856 SSKPNSPSISP--SILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKST 913 S++P P+ P S+ S +EH SPA ++ + ++ + Sbjct: 195 SARPRPPTEGPRKSVSSASEHS---------TTEPSPAARR----RPSAGGGLQRPASRS 241 Query: 914 LNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVP 973 L+ +A + + S P TP +P +QP P + +P P T P A Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRKDA-------- 292 Query: 974 VSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPA 1033 +P + PL P+ + A +A P +P + P A PP + PP Sbjct: 293 -APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA-PPSPSAPP- 349 Query: 1034 YSTQYVAYSPQQFPNQPLVQ-HVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSA 1092 S Q + P P+Q P Q+ H + SP + + + PP A P L Sbjct: 350 -SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPALALPP- 404 Query: 1093 TQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNA-TLH----PHTPHP 1147 + A P P + SP ++T S PNA +H P +P P Sbjct: 405 -----------LQAPPSPPASPPLSP-----LATPSPQA----PNALAVHLLQAPFSPPP 444 Query: 1148 QPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQAL-HLASPQQQSAIYHAGLAPTPPSMT 1206 P Q S PA PV +QA LA+P Q + P+PP+ Sbjct: 445 SPPV--------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-------VPPSPPASP 489 Query: 1207 PASNTQSPQNSFP---AAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAH 1263 P S + +P P AA P PA PP A G P P+A Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549 Query: 1264 APMMLMTTQPPGGP---QAALAQSALQPIPVSTTAHFP 1298 PM + T PP P A L Q P P S T P Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAP 586 Score = 62.0 bits (149), Expect = 4e-09 Identities = 72/252 (28%), Positives = 90/252 (35%), Gaps = 37/252 (14%) Query: 4 AAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGP- 62 A AP+ A++ +RR + PG S R G P P PSA P PP GP Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206 Query: 63 ----PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASP--GA 116 S S+ + GGG RP SR L PL+SP Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA----------TPLSSPARSG 256 Query: 117 PPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQ 176 P A T +P P+ +L P PR P GPL+ S Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS-----------PLA 305 Query: 177 QQQQQQQQQQQQPPPAAANVRKPGGSGLLAS--PAAAPSPSS----SSVSSSSATAPSSV 230 Q Q PP A + LA+ P A PSPS+ ++ S AT PS Sbjct: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ- 364 Query: 231 VAATSGGGRPGL 242 AT+ G P L Sbjct: 365 --ATTSLGSPTL 374 Score = 56.2 bits (134), Expect = 2e-07 Identities = 62/208 (29%), Positives = 84/208 (40%), Gaps = 21/208 (10%) Query: 551 PWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVST 610 P SP SPS+ PPS Q+ P+ P P PP+ PP PS P P A P P++ Sbjct: 454 PPASPPVSPSATPPS--QAPPSLAAPPLQVPPSPPASPPMSPSATPP-PQA---PPPLAA 507 Query: 611 MPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF--VSHNPPSEAATPPVARTSP 668 P +++ PP +P A P + + S F + P S ATPP + P Sbjct: 508 PPLQLAK--PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP-PQAPP 564 Query: 669 SGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAM-PIPAA 727 V P SP PR P + SGP L T A+A P P Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL---------TLALAPGPPPPP 615 Query: 728 SPTPASPASNRAVTPSSEAKDSRLQDQR 755 S +P+S S + S + S ++ R Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELR 643 Score = 51.6 bits (122), Expect = 5e-06 Identities = 62/214 (28%), Positives = 80/214 (37%), Gaps = 38/214 (17%) Query: 557 PSPSSRPPSRYQSGPNSLPPRAAT------PTRPPSRPP-----SRPSRPPSHPSA---H 602 PSP + PP + P+ P A P PP PP S P+ PP PSA Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468 Query: 603 GSPAPVSTMPKRMSSEGP--PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNP--PSEA 658 +P ++ P ++ P P MSP A P+ A + L+ P P Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ-----APPPLAAPPLQLAKPPPQAPPAL 523 Query: 659 ATPPV-ARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPT 717 ATPP+ A SP G SP P SP P PVLA+P + P+ Sbjct: 524 ATPPLQALPSPPAS-----FPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPS 576 Query: 718 EAVAMPIPAASPTPASPASNRAVTPSSEAKDSRL 751 P ASPT +P P + RL Sbjct: 577 -------PPASPTLQAPRRPPTPGPDTSVSGPRL 603 Score = 50.4 bits (119), Expect = 1e-05 Identities = 62/247 (25%), Positives = 93/247 (37%), Gaps = 25/247 (10%) Query: 495 PPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPS 554 PP + R+ +S S ++S P + PS P S S + + P S Sbjct: 200 PPTEGPRKSVS--SASEHSTTEPSPAARRRPSAGGGLQ---RPASRS---LSSSATPLSS 251 Query: 555 PCPS-PSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPK 613 P S PS+R R + P+ P+ RPP P R P+ SP + Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311 Query: 614 RMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHN---PPSEAATPPVARTSPSG 670 + S+ PP + P S+ +++ L + PPS P T PS Sbjct: 312 ALQSQAPPTL-------PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364 Query: 671 GTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTP--SGPVLASPQAGIIPTEAVAMPI-PAA 727 T S G P L SP + + P + P LA P P+ + P+ P A Sbjct: 365 ATTS---LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421 Query: 728 SPTPASP 734 +P+P +P Sbjct: 422 TPSPQAP 428 Score = 48.5 bits (114), Expect = 4e-05 Identities = 70/258 (27%), Positives = 96/258 (37%), Gaps = 65/258 (25%) Query: 7 APRSPAVATES--RRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPP-------- 56 +PR P T + R AA G + L A R+G GG P P A P Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPL---AERAGGIGGATIPESAPRAGPTRSAGTSSR 88 Query: 57 -----PPGPG----PPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL---------- 97 PP G PP++ +SP S S G G RPG GL Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVS----SPGRASGTTRPGPLGQKGLRISAEETVAR 144 Query: 98 ----GGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGC-PRPAC 152 P R + + G P P+ A +RA+ + V L RPAP PRP Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA--GTEVGLPRPAPSARPRP-- 200 Query: 153 EPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAA-A 211 P GP ++ + +P PAA R+P G L PA+ + Sbjct: 201 -PTEGP----------------RKSVSSASEHSTTEPSPAAR--RRPSAGGGLQRPASRS 241 Query: 212 PSPSSSSVSSSSATAPSS 229 S S++ +SS + + PS+ Sbjct: 242 LSSSATPLSSPARSGPSA 259 Score = 48.5 bits (114), Expect = 4e-05 Identities = 71/273 (26%), Positives = 104/273 (38%), Gaps = 50/273 (18%) Query: 495 PPGQRN-----REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGG 549 P GQ+ E ++ G + +P+ +G+ S +P R Sbjct: 128 PLGQKGLRISAEETVARGKATE-APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186 Query: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAA--TPTRPPSRPPSRPS-----RPPSHPSAH 602 V P P PS RPP+ GP A+ + T P RPS + P+ S Sbjct: 187 VGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 603 GSPAPVSTMPKRMSSEGPP-RMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATP 661 S P+S+ P R GP R +P+A HP + GL+ + PP TP Sbjct: 244 SSATPLSS-PAR---SGPSARGTPRAPAHPSQPK--------PKGLQAL--RPPQ--VTP 287 Query: 662 PVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVA 721 P +P+ G SS P S P ++ TP L T +A Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPP---TLPATPHSSSL---------TCQLA 335 Query: 722 MPIPAASPTPASPASNRAV-----TPSSEAKDS 749 P+P A P+P++P S + + TP S+A S Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368 Score = 47.4 bits (111), Expect = 9e-05 Identities = 63/215 (29%), Positives = 82/215 (38%), Gaps = 42/215 (19%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP-----------SRPSRPP--SHP 599 PS P + PP + P + PP + + T PP PP P PP + P Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526 Query: 600 SAHGSPAPVSTMPKR--MSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSE 657 P+P ++ P + S MSP A P+ V A + PPS Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP---------LLQVPPSP 577 Query: 658 AATPPV--ARTSPSGGTWSSVVSGVPRLS-PKTHRPRSPRQNSIGNTPSGPVLA--SPQA 712 A+P + R P+ G +S VSG PRL+ P P S +T SGP LA S A Sbjct: 578 PASPTLQAPRRPPTPGPDTS-VSG-PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635 Query: 713 GIIPTE-----------AVAMPIPAASPTPASPAS 736 P E A A P P A PA+ Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 670 Score = 47.0 bits (110), Expect = 1e-04 Identities = 60/209 (28%), Positives = 79/209 (37%), Gaps = 29/209 (13%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP-APVSTM 611 PSP SP + PP + PP A P P PPS P+ PP P A SP AP + Sbjct: 382 PSPPLSPLATPPPQ-------APPALALP--PLQAPPSPPASPPLSPLATPSPQAPNALA 432 Query: 612 PKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATP-PVARTSPSG 670 + + P SP Q P + S +S S PPS AA P V + P+ Sbjct: 433 VHLLQAPFSPPPSPPVQA-PFSPPASP---PVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488 Query: 671 GTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPT 730 S + P+ P P P Q + + P LA+P P+ A Sbjct: 489 PPMSPSATPPPQAPPPLAAP--PLQLAKPPPQAPPALATP------------PLQALPSP 534 Query: 731 PASPASNRAVTPSSEAKDSRLQDQRQNSP 759 PAS +PS+ S L +P Sbjct: 535 PASFPGQAPFSPSASLPMSPLATPPPQAP 563 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/198 (26%), Positives = 69/198 (34%), Gaps = 37/198 (18%) Query: 46 APGPYPSAAPPPPGPGP--------PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL 97 +P P A PPP P PPS +SPP + L Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP--------------------LAT 422 Query: 98 GGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYG 157 P P + + L +P +PP +P +P ASPP S S P+ P A P+ Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQV 481 Query: 158 PLTMSLKPQQQQQQQQQQQQQ---QQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAP-- 212 P + P Q Q + PP A + P L + PA+ P Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541 Query: 213 ---SPSSSSVSSSSATAP 227 SPS+S S AT P Sbjct: 542 APFSPSASLPMSPLATPP 559 Score = 45.8 bits (107), Expect = 3e-04 Identities = 59/228 (25%), Positives = 79/228 (34%), Gaps = 40/228 (17%) Query: 54 APPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLAS 113 AP P P PP SPP++ S P S+ L PP L +P + Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSA-------TPPSQAPPSLAAPP-----LQVPPSP 485 Query: 114 PGAPPAAPTRASPLGARASPPRSG--VSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQ 171 P +PP +P+ P +A PP + + LA+P P P P PL P Sbjct: 486 PASPPMSPSATPP--PQAPPPLAAPPLQLAKPPPQAPPALATP---PLQALPSPPASFPG 540 Query: 172 QQQQQQQQQQQQQQQQQPPPAAANV---------RKPGGSGLLASPAAAPSPS-SSSVSS 221 Q PPP A V P S L +P P+P +SVS Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600 Query: 222 SSAT---------APSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFD 260 T PS ++T G P L +S P+ +D Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSSATSTPEELRGYD 646 Score = 45.1 bits (105), Expect = 5e-04 Identities = 56/210 (26%), Positives = 75/210 (35%), Gaps = 24/210 (11%) Query: 45 AAPGPYPSAAPPPPGP----GPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGP 100 A+P PSA PP P PP SPP++ S A P + L L P Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515 Query: 101 P--RPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGP 158 P P + PL + +PPA+ +P AS P S LA P P P PV Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS--PLATPPPQAP-----PVLAA 568 Query: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSS 218 + + P Q ++ PP G L + A P P S Sbjct: 569 PLLQVPPSPPASPTLQAPRR-----------PPTPGPDTSVSGPRLTLALAPGPPPPPSR 617 Query: 219 VSSSSATAPSSVVAATSGGGRPGLGRGRNS 248 SS+ + P ++S P RG +S Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDS 647 Score = 37.0 bits (84), Expect = 0.12 Identities = 49/174 (28%), Positives = 57/174 (32%), Gaps = 24/174 (13%) Query: 4 AAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPP 63 A P++P V P +LQ P R G + GP + A PGP PP Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA-LAPGPPPP 614 Query: 64 PSRQ-----------------SSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVV 106 PSR +S P + S GG A P L P Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674 Query: 107 LLLPLA---SPGAP---PAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEP 154 PLA +PGAP P A S G G A PAPG P P Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728 Score = 36.2 bits (82), Expect = 0.21 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 11/162 (6%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP-APVSTM 611 P P P P SR PS SGP+ L +++ T P S P +A P A ++ Sbjct: 609 PGP-PPPPSRSPSSTLSGPD-LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 666 Query: 612 PKRMSSEGP--PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSP- 668 S GP P A P + G GS + GL + E+ATP P Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS-ADGLCTIYETEGPESATPAPGALDPG 725 Query: 669 -SGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLAS 709 S GT + + RSP+Q +G P G + AS Sbjct: 726 PSPGTSGGKAAAGAGAGASS---RSPKQARLGELPLGALQAS 764 Score = 35.0 bits (79), Expect = 0.47 Identities = 60/240 (25%), Positives = 87/240 (36%), Gaps = 63/240 (26%) Query: 38 SGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL 97 + R G P P S PPPP P+A G+ G G +P + R G+ Sbjct: 18 AARAPGLLTPRPPGSPRPPPP----------VTPAALRVLGAAGAVGR--KPLAERAGGI 65 Query: 98 GGPPRPFVVLLLPLASPGAPPAAPTRASPLGAR---ASPPRSG-VSLARPAPG-CPRPAC 152 GG P AP A PTR++ +R + PP SG A PA P P Sbjct: 66 GGATIP----------ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115 Query: 153 EPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPP--------------------PA 192 P G + + +P Q+ + ++ + + + P P+ Sbjct: 116 SP--GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173 Query: 193 AANVRKPGGSGL-----LASPAAAPSP-------SSSSVSSSSATAPSSVV--AATSGGG 238 A R+ +G +P+A P P S SS S S T PS ++GGG Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 77.4 bits (189), Expect = 8e-14 Identities = 171/858 (19%), Positives = 274/858 (31%), Gaps = 108/858 (12%) Query: 514 PRMGQPGSGSMPSRS--------TSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPS 565 P QPG + P+ + T +T+ P++ VP P + S + Sbjct: 1372 PTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATT 1431 Query: 566 RYQSG-------PNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPK--RMS 616 Y + P +PP + + P + P+ SA AP T+P + Sbjct: 1432 TYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLK 1491 Query: 617 SEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVS-HNPPSEAATPPVARTSPSGGTWSS 675 + G +P P S S S+ S H+ S P V TS + T + Sbjct: 1492 ATGSTHTAPPIT--PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPA 735 + T+ S R T S P +SP + P A + PTP+ P Sbjct: 1550 TSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQ 1609 Query: 736 ----------SNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISP 785 S VTPS+ + Q S + + P T P + + G + Sbjct: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHS---MPTGTIPPPTTLKATGSTH 1666 Query: 786 VVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFI 845 + + +STS + E + S + Sbjct: 1667 TAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPM 1726 Query: 846 ENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDA 905 ++S + S ++ S S+ S+T PEVTS + +P Sbjct: 1727 TVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITP--------------- 1771 Query: 906 AEQVRKSTLNPNAKEFNPRSFSQPKPSTT---PTSPRPQAQPSPSMVGHQQPTPVYTQPV 962 T P A + S P P TT PT P + P Q T Y P Sbjct: 1772 -NHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTP- 1829 Query: 963 CFAPNMMYPVPVSPGVQPLYPIPMTPMPV----NQAKTYRAVPNMPQQRQDQHHQSAMMH 1018 P+ P V P P T + Q T ++ +MP + + Sbjct: 1830 -SHPHTTLPTHV-PSFSTSLVTPSTHTVIIPTHTQMATSASIHSMP---------TGTIP 1878 Query: 1019 PAS---AAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNAR 1075 P + A G A P +T + SP F +P++ S H P + + Sbjct: 1879 PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHH---PEVTPTST 1935 Query: 1076 MMAPPTHAQPG-------LVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGS 1128 P H G S+S+++ TH+ P++ T P + T + Sbjct: 1936 TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSP-PTGSSPFS-STGPMTATSFQTTT 1993 Query: 1129 LAQQYAHPNATLHPHTP-----------HPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQ 1177 +HP TL H P H T T S S P + + Sbjct: 1994 TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLK 2053 Query: 1178 AAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQS--------PQNSFPAAQQTVFTIH 1229 A + H A P + +G + T S + A+ + S PQNS + T Sbjct: 2054 ATGSTHTAPPM---TVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQ 2110 Query: 1230 PSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAP---MMLMTTQPPGGPQAALAQSAL 1286 H+ A T + + S PS +++ P T+ P G ++ + + Sbjct: 2111 LPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPV 2170 Query: 1287 QPIPVSTTAHFPYMTHPS 1304 +S+ +H THP+ Sbjct: 2171 HSTTLSSGSHSSLSTHPT 2188 Score = 59.3 bits (142), Expect = 2e-08 Identities = 147/777 (18%), Positives = 234/777 (30%), Gaps = 135/777 (17%) Query: 555 PCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPS-HPSAHGSPAPVSTMPK 613 P P+ S P+ +S LP AT T P P+ + P + P P T Sbjct: 1332 PTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQT 1391 Query: 614 RMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTW 673 R ++E +P +H+PP+ A PV T P T Sbjct: 1392 RTTTEYTTPQTP-----------------------HTTHSPPT--AGSPVPSTGPVTATS 1426 Query: 674 SSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPAS 733 + P TPS P +PT +P S + + Sbjct: 1427 FHATTTYP-------------------TPSHPETT------LPTH-----VPPFSTSLVT 1456 Query: 734 PASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQ 793 P+++ +TP+ +++ N A P + S I+P S + Sbjct: 1457 PSTHTVITPT----HAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQA 1512 Query: 794 IDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCT 853 K L ++S ++ + P A +++ T Sbjct: 1513 HSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVA-------HTNSAT 1565 Query: 854 SGSSKPNSPSISPSILSNTEHKRGP-EVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKS 912 S P + SP S+ GP TS T+ P ++ Sbjct: 1566 SSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHP---------------QT 1610 Query: 913 TLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCF-APNMMYP 971 TL + F S S PST AQ + S H PT P A + Sbjct: 1611 TLPTHVPPF---STSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHT 1667 Query: 972 VPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM--------HPASAA 1023 P T ++ T + ++ HH A +P S Sbjct: 1668 APTM-----TLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTG 1722 Query: 1024 GPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYS---PVIQGNARMMAPP 1080 PP+ T S ++S + S H H S P + + P Sbjct: 1723 TPPMTVTTSGTSQSRSSFSTAKTST-----------SLHSHTSSTHHPEVTSTSTTSITP 1771 Query: 1081 THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATL 1140 H +S+ T+ T A + P+ + P+ IS+ + T Sbjct: 1772 NH------TSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTT 1825 Query: 1141 HPHTPHPQ---PSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALH---LASPQQQSAIY 1194 +P HP P+ P+ +H P H Q + ++H + + I Sbjct: 1826 YPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPT-HTQMATSASIHSMPTGTIPPPTTIK 1884 Query: 1195 HAGLAPTPPSMTPASN--TQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQ 1252 G T P MTP ++ +QSP + A T H S P ++ H Sbjct: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944 Query: 1253 SGM------VPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 +G S ++ P T PP G + + TT +P +HP Sbjct: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHP 2001 Score = 52.0 bits (123), Expect = 4e-06 Identities = 142/705 (20%), Positives = 215/705 (30%), Gaps = 147/705 (20%) Query: 680 VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA 739 VP + P T +P + TP P S + P + I S T SP+SN Sbjct: 1194 VPCMPPTTPQPPT--------TPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNH- 1244 Query: 740 VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKK 799 TP+S + L +S P T+ +A G+ P + Sbjct: 1245 -TPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQA-TSGLPPTAT----------- 1291 Query: 800 FKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP 859 L+ ++T ++ Q + S P+ + S++ T P Sbjct: 1292 ------LRSTATKPTVTQATTRATASTAS---------PATTST--AQSTTRTTMTLPTP 1334 Query: 860 NSPSISPSILSNTEHK---------RGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 + SP++ +T + GP T T+ P Q Q R Sbjct: 1335 ATSGTSPTLPKSTNQELPGTTATQTTGPRPTP--ASTTGPTTPQPGQPTRPTATETTQTR 1392 Query: 911 KST--LNPNAKE--FNPRSFSQPKPSTTP----------TSPRPQAQPSPSMVGHQQP-- 954 +T P +P + P PST P T P P + P ++ H P Sbjct: 1393 TTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP-SHPETTLPTHVPPFS 1451 Query: 955 ------------TPVYTQPVCFAPNMMYPVPVSPGVQPLYPI-------PMTPMPVNQAK 995 TP + Q A N P P L P+TP ++ Sbjct: 1452 TSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQ 1511 Query: 996 TYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHV 1055 + + H S+ HP TP ST+ +P N Sbjct: 1512 AHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTR--TRTPVAHTNSATSSRP 1569 Query: 1056 PHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKE 1115 P + H +PPT + P SS+ +T Y P P Sbjct: 1570 PPPFTTH---------------SPPTGSSP--FSSTGPMTATSFKTTTTYPTPSHPQTTL 1612 Query: 1116 TS--PSFYFAISTGSL--------------AQQYAHPNATLHPHT-------PHPQPSAT 1152 + P F ++ T S A ++ P T+ P T H P+ T Sbjct: 1613 PTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMT 1672 Query: 1153 PTGQQQSQHGGS-HPAPSPVQHHQH-QAAQALHLASPQQQSAIYHAGLAPTPPSMTPASN 1210 T SQ S + A + H H + S + + TPP S Sbjct: 1673 LTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSG 1732 Query: 1211 TQSPQNSFPAAQ-------QTVFTIHPSHVQPAYTN--PPHMA---HVPQAHVQSGMVPS 1258 T ++SF A+ T T HP + T+ P H + P AH S Sbjct: 1733 TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSA---- 1788 Query: 1259 HPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 ++ P T PP G + + TT +P +HP Sbjct: 1789 -TSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHP 1832 Score = 43.9 bits (102), Expect = 0.001 Identities = 69/309 (22%), Positives = 101/309 (32%), Gaps = 34/309 (11%) Query: 1027 IAATPPAYSTQYVAYSPQQFPNQP--LVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHA- 1083 +++T P+ S+ + SP Q P P L P S P + + A PPT Sbjct: 1233 LSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATL 1292 Query: 1084 ---------------QPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAIST-- 1126 +S AT A T P P TSP+ + + Sbjct: 1293 RSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPT-PATSGTSPTLPKSTNQEL 1351 Query: 1127 -GSLAQQYAHPN----ATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSP----VQHHQHQ 1177 G+ A Q P +T P TP P PT + +Q + +P H Sbjct: 1352 PGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT 1411 Query: 1178 AAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFT-IHPSHVQPA 1236 A + P ++ + PTP T P S + T I P+H Q A Sbjct: 1412 AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471 Query: 1237 YTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAH 1296 + H A + + + T AP + TT G A + + P S +H Sbjct: 1472 TSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTT---SGTSQAHSSFSTNKTPTSLHSH 1528 Query: 1297 FPYMTHPSV 1305 HP V Sbjct: 1529 TSSTHHPEV 1537 Score = 42.7 bits (99), Expect = 0.002 Identities = 170/855 (19%), Positives = 276/855 (32%), Gaps = 134/855 (15%) Query: 514 PRMGQPGSGSMPSRSTSH-TSDFNPNSGSDQRVVNGGVP-WPSPCPSPSSRP---PSRYQ 568 P P S + P +TS T+ P Q + VP + + +PS+ P+ Q Sbjct: 1579 PTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQ 1638 Query: 569 SGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMP---KRMSSEGPPRMSP 625 ++ T T PP P+ + S H +P T + +SS + S Sbjct: 1639 MATSASIHSMPTGTIPP------PTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTST 1692 Query: 626 KAQRHPRN-HRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLS 684 H + H A S ++ ++ NP S P TS + + SS + S Sbjct: 1693 SLHSHTSSTHHAEATSTSTTN----ITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTS 1748 Query: 685 -----PKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA 739 TH P ++ TP+ + T A + +P T + P Sbjct: 1749 LHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTP 1808 Query: 740 VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKK 799 ++ + + Q + P PSFS + ++P S H I Sbjct: 1809 ISSTGPVTATSFQTTTTYPTPSHPHTTLPTHV-PSFSTSL---VTP--STHTVII----- 1857 Query: 800 FKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP 859 P+ T + ++ G + + ++S + S Sbjct: 1858 --------PTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSF 1909 Query: 860 NSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK 919 ++ S S+ +T PEVT +P + T P A Sbjct: 1910 STAKTSTSLPYHTSSTHHPEVTPTSTTNITP----------------KHTSTGTRTPVAH 1953 Query: 920 EFNPRSFSQPKPSTT---PTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVP--- 973 + S P P TT PT P + P Q T Y P + VP Sbjct: 1954 TTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFS 2013 Query: 974 ---VSPGVQPLYPIPMTPMP----VNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPP 1026 V+P + T M ++ T P + H + P + Sbjct: 2014 TSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAP---PMTVTTSG 2070 Query: 1027 IAATPPAYSTQYVAYS--------PQQF----PNQPLVQHVPHYQSQHPHVYSPVIQGNA 1074 + T ++ST + S PQ P+ P+ +PH S +PV N Sbjct: 2071 TSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS----ATTPVSTTNQ 2126 Query: 1075 RMMA-PPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQY 1133 + P+ + P VSS + QT + + TS SF A + Sbjct: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSP--------SVGTSSSFVSAPVHSTTLSSG 2178 Query: 1134 AHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAI 1193 +H + + HP T SA+P SP +A ++SP SA+ Sbjct: 2179 SHSSLSTHPTTA--SVSASPLFPS-----------SPAASTTIRATLPHTISSPFTLSAL 2225 Query: 1194 YHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQS 1253 P TP+S+ S +FP+ +T + H + + + + S Sbjct: 2226 LPISTVTVSP--TPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTS 2283 Query: 1254 GM------VPSHPTAHAPMMLMTTQPPG---GPQAALAQSAL-------QPIPVSTTAHF 1297 G V PT +P+ +TT+ PG P S+L PVS+ Sbjct: 2284 GFVSLTSGVTGIPT--SPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLG-T 2340 Query: 1298 PYMTHPSVQAHHQQQ 1312 P T P V + +QQ Sbjct: 2341 PTPTSPGVCSVREQQ 2355 Score = 40.0 bits (92), Expect = 0.015 Identities = 101/504 (20%), Positives = 158/504 (31%), Gaps = 49/504 (9%) Query: 513 SPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPS--PCPSPSSRPPSRYQSG 570 +P G+ + + +TS TS P + G P S P + S + + Y Sbjct: 1770 TPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTY--- 1826 Query: 571 PNSLPPRAATPTRPPS------RPPSRPSRPPSHP------SAHGSPAPVSTMPKRMSSE 618 P P PT PS P + P+H S H P P + + Sbjct: 1827 PTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKAT 1886 Query: 619 GPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT--PPVARTSPSGGTWSSV 676 G +P P S S S+ S P ++T P V TS + T Sbjct: 1887 GSTHTAPPMT--PTTSGTSQSPSSFSTAKTSTSL-PYHTSSTHHPEVTPTSTTNITPKHT 1943 Query: 677 VSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPA- 735 +G T S R + T S P +SP + P A + PTP+ P Sbjct: 1944 STGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQT 2003 Query: 736 ---------SNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPV 786 S VTPS+ Q S + + P T P + + G + Sbjct: 2004 TLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS---TPTGTVPPPTTLKATGSTHT 2060 Query: 787 VSEHRKQIDDLKKFKNDFRLQPSSTS--ESMDQLLNKNREGEKSRDLIKDKIEPSAKDSF 844 + + F +S+S S L + S + S+ + Sbjct: 2061 APPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTP 2120 Query: 845 IENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKD 904 + ++ +S S P++PS S + ++ S G +S + Sbjct: 2121 VSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSH 2180 Query: 905 AAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCF 964 ++ +T + +A P S P STT + P SP + P T Sbjct: 2181 SSLSTHPTTASVSASPLFP---SSPAASTTIRATLPHTISSPFTLSALLPISTVT----- 2232 Query: 965 APNMMYPVPVSPGVQPLYPIPMTP 988 + P P S P TP Sbjct: 2233 ----VSPTPSSHLASSTIAFPSTP 2252 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 77.4 bits (189), Expect = 8e-14 Identities = 124/504 (24%), Positives = 184/504 (36%), Gaps = 92/504 (18%) Query: 447 EIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISW 506 E+ S + K D + +Y + SS G S ++ + + +N EV Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV--- 517 Query: 507 GSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCP-----SPSS 561 G R++SP S P + TS S PSP P SPS Sbjct: 518 GRRRRHSPSRSASPS---PRKRQKETSPRGRRRRS-----------PSPPPTRRRRSPSP 563 Query: 562 RPPSRYQSGPNSLPPRAATPTRPPSR---------------------PPSRPSRPPSHPS 600 PP R + P PPR TP+ PP R P R + PP P Sbjct: 564 APPPRRRRTPTP-PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622 Query: 601 AHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT 660 SP+P PKR S PP PK + P R S S S + + Sbjct: 623 RRASPSP---PPKRRVSHSPP---PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP 676 Query: 661 PPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV 720 P R SPS RPR+P+ +S +SPQ P+ + Sbjct: 677 QPNKRHSPS------------------PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS- 717 Query: 721 AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNS----PAGNKENIKPNETSPSFS 776 PI S TP +A +PS ++ R+ R S PA K P SP S Sbjct: 718 TRPIRRVSRTPEPKKIKKAASPSPQSV-RRVSSSRSVSGSPEPAAKK---PPAPPSPVQS 773 Query: 777 KAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKI 836 ++ + SP V +KK K+ PS S + K ++ +K + KDK Sbjct: 774 QSPSTNWSPAV--------PVKKAKSP-TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824 Query: 837 EPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEK 896 K E + + + + P + + + + L+ E PE +T S A + Sbjct: 825 HKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKK---ETESEA-EDNL 880 Query: 897 DDKEE--KKDAAEQVRKSTLNPNA 918 DD E+ ++ A +RK+ ++P + Sbjct: 881 DDLEKHLREKALRSMRKAQVSPQS 904 Score = 67.8 bits (164), Expect = 7e-11 Identities = 148/738 (20%), Positives = 239/738 (32%), Gaps = 118/738 (15%) Query: 554 SPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAH----------- 602 SP P S P R + +S PR T +R PS P + + P P Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA 238 Query: 603 GSPAPVSTMPKRMSSEGPPRMSP---------KAQRHPRNHRVSAGRGSISSGLEFVSHN 653 S + + +PK P SP K + PR+ S R S SH Sbjct: 239 TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS--RSPSHT 296 Query: 654 PP-------SEAATP-----PVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNT 701 P S + +P P R SP T PR P R R R Sbjct: 297 RPRRRHRSRSRSYSPRRRPSPRRRPSPRRRT-------PPRRMPPPPRHRRSRSPVRRRR 349 Query: 702 PSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAG 761 S L+ + + + + P T + P R ++PS+ R R + PA Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR---HRPSPPAT 406 Query: 762 NKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNK 821 + + T ++ +S VS R K + R PS + L++ Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVS--VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSE 464 Query: 822 NREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVT 881 + E + + D ++ + +N S+ SGSS S S H + EV Sbjct: 465 SEEDKGGKMAAADSVQ-QRRQYRRQNQQSSSDSGSS-----SSSEDERPKRSHVKNGEVG 518 Query: 882 SQGVQTSSPACKQEKDDKEEKKDAAEQVRK---STLNPNAKEFNPRSFSQPKPSTTPTSP 938 + + SP+ ++ +K+ + + R+ + P + +P P+ TPT P Sbjct: 519 RR--RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPP 576 Query: 939 RPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYR 998 + PSP Y+ P+ Y SP P P P + R Sbjct: 577 PRRRTPSPPPRRRSPSPRRYSPPI----QRRY----SPSPPPKRRTASPPPPPKR----R 624 Query: 999 AVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQY-VAYSPQQFPN-----QPLV 1052 A P+ P +R+ H P + P P+ S+++ SP + QP Sbjct: 625 ASPSPPPKRRVSHSPP----PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680 Query: 1053 QHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPY 1112 +H P + + P S P + G SS + T + + P Sbjct: 681 RHSPSPRPRAPQTSS-----------SPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729 Query: 1113 NKE------TSPSFYFAISTGSLAQQYAHPNATLHPHTP--------------------- 1145 K+ SP +S+ P A P P Sbjct: 730 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKA 789 Query: 1146 -HPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPS 1204 P PS +P + GG + H+ H ++++ A A TP + Sbjct: 790 KSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAA 849 Query: 1205 MTPASNTQSPQNSFPAAQ 1222 + A+ T + + A + Sbjct: 850 IAAATTTLAQEEPVAAPE 867 Score = 65.1 bits (157), Expect = 4e-10 Identities = 133/605 (21%), Positives = 204/605 (33%), Gaps = 94/605 (15%) Query: 465 RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSM 524 RS Y+ +R S R + +PP R+R R SP + S + Sbjct: 303 RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR--------RSRSPVRRRRRSSAS 354 Query: 525 PSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQS-GPNSLPPRAATPTR 583 S S+S +S S P P +S PP + + P++ PPR Sbjct: 355 LSGSSSSSSSSRSRSP------------PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402 Query: 584 PPSRPPSRPSRPPS-HPSAHGSPAPVSTMPKRMSSE------GPPRMSPKAQRHPRNHRV 636 PP+ PP + P+ S + VS P R S + R SP PR + Sbjct: 403 PPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVEL 462 Query: 637 S----------AGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV----PR 682 S A S+ ++ N S + + + + S V +G R Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522 Query: 683 LSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASP----TPASPASNR 738 SP SPR+ +P G SP PT P PA P TP P R Sbjct: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPP--PTRRRRSPSPAPPPRRRRTPTPPPRRR 580 Query: 739 AVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLK 798 TPS + +R + P + SPS P + R Sbjct: 581 --TPSPPPRRRSPSPRRYSPPIQRR-------YSPSPPPKRRTASPPPPPKRRASPSPPP 631 Query: 799 KFKNDFRLQPSSTSESMDQ-----LLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCT 853 K + P S + + L +K+R+G ++ P + Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691 Query: 854 SGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKST 913 SS P P + S+ + ++ P +++ ++ S + K K+ + + VR+ + Sbjct: 692 QTSSSP--PPVRRGASSSPQRRQSPSPSTRPIRRVS-RTPEPKKIKKAASPSPQSVRRVS 748 Query: 914 LNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVP 973 + RS S S P + +P A PSP V Q P + N VP Sbjct: 749 --------SSRSVS---GSPEPAAKKPPAPPSP--VQSQSP----------STNWSPAVP 785 Query: 974 VSPGVQPLYPIPMTPMPVNQ---AKTYRAVPNMPQQRQDQH--HQSAMMHPASAAGPPIA 1028 V P P P P +Q K + + ++ +H H+ A AA A Sbjct: 786 VKKAKSPT-PSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAA 844 Query: 1029 ATPPA 1033 TP A Sbjct: 845 VTPAA 849 Score = 44.7 bits (104), Expect = 6e-04 Identities = 58/234 (24%), Positives = 88/234 (37%), Gaps = 32/234 (13%) Query: 18 RRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPP------ 71 RR + +R +R S RG +P P P+ P P PPP R+ +P Sbjct: 521 RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580 Query: 72 SASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARA 131 + S + P +R PP+ ASP PP RASP + Sbjct: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK------RRTASP--PPPPKRRASP----S 628 Query: 132 SPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQ----QQQQQQQQQQQQQQQQQQ 187 PP+ VS + P P+ PV + SL + ++ + ++ + Q ++ Sbjct: 629 PPPKRRVSHSPP----PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684 Query: 188 QPPPAAANVRK---PGGSGLLASP--AAAPSPSSSSVSSSSAT-APSSVVAATS 235 P P A P G +SP +PSPS+ + S T P + A S Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAAS 738 Score = 42.7 bits (99), Expect = 0.002 Identities = 62/237 (26%), Positives = 83/237 (35%), Gaps = 43/237 (18%) Query: 8 PRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSA---------APPPP 58 PRS + ++SR +R P S RP RR +P PS PP Sbjct: 276 PRSRS-RSKSRSRTRSRSP---SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRR 331 Query: 59 GPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPP 118 P PP R+S P S G + S R PP+ P +PP Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS---PPKK------PPKRTSSPP 382 Query: 119 AAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQ 178 R SP ASPPR RP+P P T P + + QQ Sbjct: 383 RKTRRLSP---SASPPRRR---HRPSP------------PAT---PPPKTRHSPTPQQSN 421 Query: 179 QQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATS 235 + ++ + P + V K G+ SP+ AP P +S S + AA S Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS 478 Score = 35.8 bits (81), Expect = 0.28 Identities = 47/176 (26%), Positives = 64/176 (36%), Gaps = 42/176 (23%) Query: 29 RSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 RS R RRS G++ S + PP PP R SSPP + Sbjct: 342 RSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK--PPKRTSSPPRKT-------------- 385 Query: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPG-- 146 RRL PPR SP A P TR SP +++ R S +PG Sbjct: 386 ---RRLSPSASPPRR-----RHRPSPPATPPPKTRHSPTPQQSNRTRK--SRVSVSPGRT 435 Query: 147 --------------CPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 P PA +P L+ S + + + QQ++Q ++Q QQ Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQ 491 Score = 32.3 bits (72), Expect = 3.1 Identities = 58/316 (18%), Positives = 116/316 (36%), Gaps = 37/316 (11%) Query: 879 EVTSQGVQTSSPACKQEKDDKEEKKDAAE-----QVRKSTLNPNAKEF---NPRSFS--- 927 E+ + ++ A +++D+ ++K+D E + R+ + +P ++ +PR S Sbjct: 130 EIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPV 189 Query: 928 ----------QPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPG 977 P+ T SP P + +P+ +P + P Sbjct: 190 RRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPK 249 Query: 978 VQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQ 1037 +P+ P P P P +K + + R +S + P + ++ Sbjct: 250 PEPI-PEPKEPSPEKNSKKEK---EKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305 Query: 1038 YVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGA 1097 +YSP++ +P + P + + P P + R +P + S+S + + Sbjct: 306 SRSYSPRR---RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS--SASLSGSSS 360 Query: 1098 HEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPH---TPHPQPSATPT 1154 + + PK P + +SP T L+ + P P TP P+ +PT Sbjct: 361 SSSSSRSRSPPKKPPKRTSSP----PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT 416 Query: 1155 GQQQSQHGGSHPAPSP 1170 QQ ++ S + SP Sbjct: 417 PQQSNRTRKSRVSVSP 432 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 76.3 bits (186), Expect = 2e-13 Identities = 163/739 (22%), Positives = 248/739 (33%), Gaps = 121/739 (16%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP---APVS 609 P P SP S PP P P + PPS P PP S P +P+S Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555 Query: 610 TMPKRMSSEGPP---RMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT--PPVA 664 P+ + + PP R+SP + P +S E +PP EA+ PP Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESP-----------MSPPPEESPMSPPPEASRLFPPFE 604 Query: 665 RTSPSGGTWSSVVSGVPRLSPKTHRPR-SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMP 723 + S S +S P S + P SP +P P + +P + P Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664 Query: 724 IPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGI 783 P SP + P +P EA SRL ++SP P E SP+ E+ + Sbjct: 665 PPEESPL-SPPPEESPTSPPPEA--SRLSPPPEDSPTS-----PPPEDSPASPPPEDSLM 716 Query: 784 SPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDS 843 S + E L + +L P S + + E S + + P A++ Sbjct: 717 SLPLEE-----SPLLPLPEEPQLCPRSEGPHLSP---RPEEPHLSPRPEEPHLSPQAEEP 768 Query: 844 FIENSSSN-CTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEK 902 + C + P P +SP PE QT P E+ Sbjct: 769 HLSPQPEEPCLC--AVPEEPHLSPQA-EGPHLSPQPEELHLSPQTEEP----HLSPVPEE 821 Query: 903 KDAAEQVRKSTLNPNAKE--FNPR---SFSQPKPSTTPTSPRPQAQPS-PSMVGHQQPTP 956 + Q +S L+P ++E +PR S P+ P SPRP+ P P + P Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881 Query: 957 VYTQP--VCFAPNMMYPVPVSPGVQPLYPIPMT---------------------PMPVNQ 993 ++ P +P + P PG PL P+P P P++ Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941 Query: 994 AKTYRAVPNMPQQRQDQHHQSAM--MHPASAAGPPIAATPPAYSTQYVAYSPQQFP---- 1047 T A P + + ++ A P S PI TP + + P+ P Sbjct: 942 IITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMIL 1001 Query: 1048 ----NQPLVQHVPHYQSQHPHVYSPVIQGN-ARMMAPPTHAQP--------------GLV 1088 P+ P P SP++Q + +PP+ P G V Sbjct: 1002 PPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKV 1061 Query: 1089 SSSATQYGAHEQTHAMYACPKLPYNKETS---------------PSFYFAISTGSLAQQY 1133 + + HE + P+ P + ++ PS A+ S + Sbjct: 1062 VGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121 Query: 1134 AHPNATLHPHTPHPQPSATPTGQQQSQHGGS-------HPAPSPVQHHQHQAAQALHLAS 1186 P + P+P TP G S+ GS AP + Q S Sbjct: 1122 TAPLDGIDAPGSQPEPGQTP-GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGS 1180 Query: 1187 PQQQSAIYHAGLAPTPPSM 1205 P ++ A +APTPP++ Sbjct: 1181 PCEEQEEPRAPVAPTPPTL 1199 Score = 75.1 bits (183), Expect = 4e-13 Identities = 128/531 (24%), Positives = 185/531 (34%), Gaps = 77/531 (14%) Query: 553 PSPCPSPSSRPP--SRYQSGPNSLP----PRAATPTRP----PSRPPSRPSRPPSHPSAH 602 P P SP+S PP SR P LP P A +RP P PP P P P Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP--PEESPLSPPPE 508 Query: 603 GSP-APVSTMPKRMSSEGPPR------MSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPP 655 SP +P+ P E PP +SP + P + +S E + +PP Sbjct: 509 SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE--ESPLSPPPEELPTSPP 566 Query: 656 SEAA--TPPVARTSPSGGTWSSVVSGVPRLS----PKTHRPRS--PRQNSIGNTPSGPVL 707 EA+ +PP + S S +S P S P P S P ++ + P L Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626 Query: 708 ASP----QAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNK 763 + P P E+ P P S P +R P E+ S ++ SP Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEA 686 Query: 764 ENIK-PNETSPSFSKAENKGISPVVSEHRKQI----DDLKKFKNDFRLQPSSTSESMDQL 818 + P E SP+ E+ SP + + L + +L P S L Sbjct: 687 SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG---PHL 743 Query: 819 LNKNREGEKSRDLIKDKIEPSAKDSFIE-NSSSNCTSGSSKPNSPSISPSILSNTEHKRG 877 + E S + + P A++ + C + P P +SP Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL--CAVPEEPHLSPQ-AEGPHLSPQ 800 Query: 878 PEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKE--FNPR---SFSQPKPS 932 PE QT P E+ + Q +S L+P ++E +PR S P+ Sbjct: 801 PEELHLSPQTEEP----HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE 856 Query: 933 TTPTSPRPQAQP-SPSMVGHQQPTPVYTQP--VCFAPNMMYPVPVSPGVQPLYPIPMTPM 989 P SPRP+ P P + P++ P +P + P PG PL P+P Sbjct: 857 KPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP---- 912 Query: 990 PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPI-----AATPPAYS 1035 +P + S + P PP+ AA PPA S Sbjct: 913 -----------EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS 952 Score = 50.1 bits (118), Expect = 1e-05 Identities = 78/293 (26%), Positives = 102/293 (34%), Gaps = 49/293 (16%) Query: 483 GHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSD 542 G + T + P R +V G P+ P PS SH F P S +D Sbjct: 2318 GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPS-PPSHPDIFRPGSYTD 2376 Query: 543 QRVVNGGVPWPSPCP--------------SPSSRPPSRYQSGPNS---LPPR-------A 578 P P P P P SR P+ QS +S L PR Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC 2436 Query: 579 ATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSA 638 +P P + P SRPPS P + AP+ P+ PP ++ KA S Sbjct: 2437 PSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ----PPEVAFKAGSLA---HTSL 2489 Query: 639 GRGSISSGL----------EFVSHNPPSEAATPP----VARTSPSGGTWSSVVSGVPRLS 684 G G + L + S PP+ +P V SP T+ V G P L Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAV-GEPSLK 2548 Query: 685 PKTHRPRSPRQNSI-GNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPAS 736 P +P P + I + GP L PQ+ T A P+ SP S S Sbjct: 2549 PPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY-TVATGNFHPSGSPLGPSSGS 2600 Score = 45.1 bits (105), Expect = 5e-04 Identities = 22/26 (84%), Positives = 23/26 (88%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L+ QQQQQ QQQQQQ QQQQQQQQQQ Sbjct: 3940 LQQQQQQQLQQQQQQLQQQQQQQQQQ 3965 Score = 44.7 bits (104), Expect = 6e-04 Identities = 22/26 (84%), Positives = 23/26 (88%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L+ QQQQ QQQQQQQQQQ QQQQQQQ Sbjct: 3948 LQQQQQQLQQQQQQQQQQFQQQQQQQ 3973 Score = 43.9 bits (102), Expect = 0.001 Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 10/121 (8%) Query: 111 LASPGAPPAAPTRASPLGARASPPRSGV--SLARPAPGC-PRPACEPVYGPLTMSLKPQQ 167 +A PG P P + L + SG SLA P+ G P GP + L+ +Q Sbjct: 3662 MALPGQP-GGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ 3720 Query: 168 QQQQQQQQQ------QQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSS 221 Q QQQ+ Q QQQQQQQQQQ A ++ G G+ + A P P S Sbjct: 3721 LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780 Query: 222 S 222 S Sbjct: 3781 S 3781 Score = 43.5 bits (101), Expect = 0.001 Identities = 21/23 (91%), Positives = 21/23 (91%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQQQQQQQ QQQQQQQ QQQQQQ Sbjct: 3932 QQQQQQQQLQQQQQQQLQQQQQQ 3954 Score = 43.1 bits (100), Expect = 0.002 Identities = 21/23 (91%), Positives = 21/23 (91%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQQ QQQQQQQQQQ QQQQQQQQ Sbjct: 3952 QQQLQQQQQQQQQQFQQQQQQQQ 3974 Score = 42.4 bits (98), Expect = 0.003 Identities = 108/501 (21%), Positives = 164/501 (32%), Gaps = 109/501 (21%) Query: 837 EPSAKDSFIENSSSNCTS---------GSSKPNSPSISPSILSNTEHKRGPEVTSQGVQT 887 +PS D F++ + + G K + P +SP E ++ EV + + Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG--ESRKALEVKKEELGA 2294 Query: 888 SSPACKQEKDDKEEKKDAAEQ----------VRKSTLNPNAKEFNPRSFS-----QPKPS 932 SSP+ + + V K+ L P A + P+S Q P Sbjct: 2295 SSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPP 2354 Query: 933 TTPTSPRPQAQPS-------------PSMVGHQQPTPVYTQPVCFAPNMMYP------VP 973 +P P + P P + QP P + C P P VP Sbjct: 2355 AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP--PESCCALPPRSLPSDPFSRVP 2412 Query: 974 VSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPA 1033 SP Q P+TP P++ A+ + P P+ + P + PP+ Sbjct: 2413 ASPQSQSSSQSPLTPRPLS-AEAFCPSPVTPRFQ----------------SPDPYSRPPS 2455 Query: 1034 YSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSAT 1093 ++P P +P P + A +A + G +A Sbjct: 2456 RPQSRDPFAPLHKPPRP---------------QPPEVAFKAGSLAHTSLGAGGF--PAAL 2498 Query: 1094 QYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHP--HTPHPQPSA 1151 G + HA + P N SP + T S ++ P A P P PQP Sbjct: 2499 PAGPAGELHAKVPSGQ-PPNFVRSPGTGAFVGTPS-PMRFTFPQAVGEPSLKPPVPQPGL 2556 Query: 1152 TPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLA----SPQQQSAIYHAGLAP-TPPSMT 1206 P S G P + A H + P S GL+P PPS+ Sbjct: 2557 PPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL 2616 Query: 1207 PASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPM 1266 P +P S P + H + + T+P P +GM S TA P Sbjct: 2617 P---PPAPDGSLP------YLSHGASQRSGITSPVEKREDP----GTGMGSSLATAELP- 2662 Query: 1267 MLMTTQPPGGPQAALAQSALQ 1287 TQ PG + L+Q+ L+ Sbjct: 2663 ---GTQDPG--MSGLSQTELE 2678 Score = 42.4 bits (98), Expect = 0.003 Identities = 22/43 (51%), Positives = 28/43 (65%) Query: 146 GCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 G P+ + +P+ + + Q QQQQQ QQQQQQQ QQQQQ Q Sbjct: 3885 GQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQ 3927 Score = 42.4 bits (98), Expect = 0.003 Identities = 21/26 (80%), Positives = 22/26 (84%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L+ QQQQQ QQQQQ QQQQ QQQQQQ Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQ 3937 Score = 42.4 bits (98), Expect = 0.003 Identities = 21/26 (80%), Positives = 22/26 (84%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L+ QQQ QQQQ QQQQQQQQ QQQQQ Sbjct: 3920 LQQQQQLQQQQLQQQQQQQQLQQQQQ 3945 Score = 42.4 bits (98), Expect = 0.003 Identities = 21/26 (80%), Positives = 22/26 (84%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L+ QQ QQQQQQQQ QQQQQQQ QQQ Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQ 3951 Score = 42.4 bits (98), Expect = 0.003 Identities = 21/26 (80%), Positives = 22/26 (84%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L+ QQQQQQ QQQQQQQ QQQQQQ Q Sbjct: 3931 LQQQQQQQQLQQQQQQQLQQQQQQLQ 3956 Score = 42.4 bits (98), Expect = 0.003 Identities = 25/49 (51%), Positives = 27/49 (55%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP 214 Q QQQQQQQ QQQQQQ QQQQQQ ++ GLL SP Sbjct: 3939 QLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSP 3987 Score = 41.6 bits (96), Expect = 0.005 Identities = 81/282 (28%), Positives = 98/282 (34%), Gaps = 67/282 (23%) Query: 474 VQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTS 533 +QRN+ +E + PPG SWG+ +SP Q G P T S Sbjct: 2695 IQRNTLRQEKETAAAAAGAVGPPG-------SWGA-EPSSPAFEQLSRGQTPFAGTQDKS 2746 Query: 534 DFNPNSGSDQRVVNGGVPWPSPCPSPS--SRPP-----------SRYQSG---------- 570 G ++G + P PS SRPP SR G Sbjct: 2747 SL---VGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAP 2803 Query: 571 -PNSLPPR-------------AATPTR--PPSRPPSRPSRPPSHPSAHGSP-APVSTMPK 613 P SLP + AAT R +R PS P P A GSP A +ST Sbjct: 2804 YPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG-PELGRQALGSPLAGIST--- 2859 Query: 614 RMSSEGPPRMSPK--AQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVA----RTS 667 R+ G P P AQ H V G G G F PP PV+ R + Sbjct: 2860 RLPGPGEPVPGPAGPAQFIELRHNVQKGLGP--GGTPFPGQGPPQRPRFYPVSEDPHRLA 2917 Query: 668 PSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTP--SGPVL 707 P G VSG+P P P NS+ TP GP L Sbjct: 2918 PE-GLRGLAVSGLPPQKPSA-PPAPELNNSLHPTPHTKGPTL 2957 Score = 41.2 bits (95), Expect = 0.007 Identities = 21/30 (70%), Positives = 22/30 (73%) Query: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L + QQ QQQQQQQ QQQQQQ QQQQQ Sbjct: 3931 LQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960 Score = 40.8 bits (94), Expect = 0.009 Identities = 20/23 (86%), Positives = 20/23 (86%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQQQ QQQQQQQ QQQQQ QQQQ Sbjct: 3908 QQQQLQQQQQQQLQQQQQLQQQQ 3930 Score = 40.8 bits (94), Expect = 0.009 Identities = 20/23 (86%), Positives = 20/23 (86%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQQQ QQQQQ QQQQ QQQQQQQ Sbjct: 3916 QQQQLQQQQQLQQQQLQQQQQQQ 3938 Score = 40.8 bits (94), Expect = 0.009 Identities = 20/23 (86%), Positives = 20/23 (86%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQQ QQQQQ QQQQ QQQQQQQQ Sbjct: 3917 QQQLQQQQQLQQQQLQQQQQQQQ 3939 Score = 40.8 bits (94), Expect = 0.009 Identities = 20/23 (86%), Positives = 20/23 (86%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQ QQQQ QQQQQQQQ QQQQQQ Sbjct: 3924 QQLQQQQLQQQQQQQQLQQQQQQ 3946 Score = 40.8 bits (94), Expect = 0.009 Identities = 20/23 (86%), Positives = 20/23 (86%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 Q QQQQ QQQQQQQQ QQQQQQQ Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQQQQ 3947 Score = 40.8 bits (94), Expect = 0.009 Identities = 20/23 (86%), Positives = 20/23 (86%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 Q QQQQQQQQ QQQQQQQ QQQQ Sbjct: 3930 QLQQQQQQQQLQQQQQQQLQQQQ 3952 Score = 40.8 bits (94), Expect = 0.009 Identities = 21/30 (70%), Positives = 22/30 (73%) Query: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L + Q QQQQQQ QQQQQQQQQQ QQQ Sbjct: 3940 LQQQQQQQLQQQQQQLQQQQQQQQQQFQQQ 3969 Score = 40.4 bits (93), Expect = 0.011 Identities = 20/25 (80%), Positives = 21/25 (84%) Query: 163 LKPQQQQQQQQQQQQQQQQQQQQQQ 187 L+ QQQ QQQQQQQ QQQQQ QQQQ Sbjct: 3906 LQQQQQLQQQQQQQLQQQQQLQQQQ 3930 Score = 40.0 bits (92), Expect = 0.015 Identities = 33/89 (37%), Positives = 39/89 (43%), Gaps = 22/89 (24%) Query: 163 LKPQQQQQQQQQQQQQQQQQ-------------QQQQQQ--------PPPAAANVRKPGG 201 L+ QQQQQQQQ QQQQQQQQ QQQQQQ P + PG Sbjct: 3955 LQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGA 4014 Query: 202 SG-LLASPAAAPSPSSSSVSSSSATAPSS 229 G L + +VSS + PS+ Sbjct: 4015 LGPTLLLTGKEQNTVDPAVSSEATEGPST 4043 Score = 39.3 bits (90), Expect = 0.025 Identities = 55/200 (27%), Positives = 72/200 (36%), Gaps = 26/200 (13%) Query: 1126 TGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLA 1185 TG L + A P P P P P A TG G HP P P + + L Sbjct: 4271 TGPLQELGAGPRPQGPPRLPAP-PGALSTGPVL---GPVHPTPPPSSPQEPKRPSQLPSP 4326 Query: 1186 SPQQQSAIYHAGLAPTPPSMTPASNTQS----PQNSFPAAQQTVFTIHPSHVQPAYTNPP 1241 S Q + A L PT P TP + P PAA Q T+ + P +PP Sbjct: 4327 SSQLPT---EAQLPPTHPG-TPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGP--WDPP 4380 Query: 1242 HMAHVPQAHVQSGMVPSH-------PTAHAPMMLMTTQPPGGPQAALAQSAL-----QPI 1289 Q QS +VP H A + + +P P A AQS +PI Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440 Query: 1290 PVSTTAHFPYMTHPSVQAHH 1309 T++ + P +A H Sbjct: 4441 GAPGTSNHLLLAGPRSEAGH 4460 Score = 38.9 bits (89), Expect = 0.033 Identities = 56/211 (26%), Positives = 76/211 (36%), Gaps = 36/211 (17%) Query: 51 PSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGG-----------GAFRPGSRRLLGLGG 99 PS PP P PG PP P + FG G G F P S LG Sbjct: 2545 PSLKPPVPQPGLPP-----PHGINSHFGPGPTLGKPQSTNYTVATGNFHP-SGSPLGPSS 2598 Query: 100 PPRPFVVLLLPLASPGA-PPAAPTRASPLGARASPPRSGVSL---ARPAPG--------- 146 L PL P PP AP + P + + RSG++ R PG Sbjct: 2599 GSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLAT 2658 Query: 147 --CPRPACEPVYGPLTMSLKPQQQQQQQQQ----QQQQQQQQQQQQQQPPPAAANVRKPG 200 P + G L+ Q+Q+Q+ ++ QQ Q+ +Q+++ AA V PG Sbjct: 2659 AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718 Query: 201 GSGLLASPAAAPSPSSSSVSSSSATAPSSVV 231 G S A S + SS+V Sbjct: 2719 SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLV 2749 Score = 38.5 bits (88), Expect = 0.043 Identities = 20/30 (66%), Positives = 21/30 (70%) Query: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ 188 L + Q QQQQQ QQQQ QQQQQQQQ Q Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ 3941 Score = 38.1 bits (87), Expect = 0.056 Identities = 19/23 (82%), Positives = 19/23 (82%) Query: 166 QQQQQQQQQQQQQQQQQQQQQQQ 188 QQ QQQQQQQ QQQQQ QQQQ Q Sbjct: 3910 QQLQQQQQQQLQQQQQLQQQQLQ 3932 Score = 37.7 bits (86), Expect = 0.073 Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 9/101 (8%) Query: 525 PSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLP--PRAATPT 582 P T H+ +N S D R ++ +P P S PPS P S P P PT Sbjct: 4886 PEPPTQHSYTYNV-SNLDVRQLS------APPPEEPSPPPSPLAPSPASPPTEPLVELPT 4938 Query: 583 RPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRM 623 P + PP P + P P + P+ PPR+ Sbjct: 4939 EPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979 Score = 37.4 bits (85), Expect = 0.095 Identities = 58/239 (24%), Positives = 82/239 (34%), Gaps = 36/239 (15%) Query: 8 PRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGP-PPSR 66 P + ++ A+ P L RP S +P P S PPP P P Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESP-----LSPPPEESPLSPPPESSPFSPLE 516 Query: 67 QS--SPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPL-ASPGAPP--AAP 121 +S SPP S P S L PP L P SP +PP P Sbjct: 517 ESPLSPPEES--------------PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562 Query: 122 TRASPLGARASPPRSGVSLARP---APGCPRPACEPVYGPLTMS-LKPQQQQ---QQQQQ 174 T P +R SPP ++ P +P P P ++ P S L P ++ + Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622 Query: 175 QQQQQQQQQQQQQQPPPAAANVRKPGG----SGLLASPAAAPSPSSSSVSSSSATAPSS 229 + + PPP + + P S L +P P S +S +P+S Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681 Score = 37.4 bits (85), Expect = 0.095 Identities = 45/159 (28%), Positives = 58/159 (36%), Gaps = 31/159 (19%) Query: 35 ARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRL 94 AR++ R P P A PP P SP + + G + + G +P + + Sbjct: 2094 ARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPA---GLSTSADGFLKPPAGSV 2150 Query: 95 LGLGGPPRPFVVL------------------LLPLAS--PGAPPAAPTRASPLGARASPP 134 G P F+ L PL P APP P SP GA A PP Sbjct: 2151 PGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210 Query: 135 RSGVSLARPAPGCP-----RPACEPVYGPLTMS--LKPQ 166 G S +RP G P P P + P T LKP+ Sbjct: 2211 MLGAS-SRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR 2248 Score = 36.6 bits (83), Expect = 0.16 Identities = 39/129 (30%), Positives = 48/129 (37%), Gaps = 16/129 (12%) Query: 46 APGPYPSAAPPPP-----GPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLG---- 96 +P P S PPP P P S S PP AS F + P L Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623 Query: 97 --LGGPPRPFVVLLLPLASPGAPPAAPTRASPLG--ARASPPRSGVSLARP---APGCPR 149 L PP + P SP +PP +R SPL +R SPP L+ P +P P Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP 683 Query: 150 PACEPVYGP 158 P + P Sbjct: 684 PEASRLSPP 692 Score = 36.6 bits (83), Expect = 0.16 Identities = 44/166 (26%), Positives = 54/166 (32%), Gaps = 33/166 (19%) Query: 56 PPPGPGP------PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLL 109 P P P P PP R GG + GS P +L Sbjct: 4080 PQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPH---LLAQ 4136 Query: 110 PLASPGAPPAAPTR-----ASPLGARASPPRSGVSLARPAP------GCPRPACEPVYGP 158 P S G P + T+ P+ R +G +P P G P P G Sbjct: 4137 PSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQ 4196 Query: 159 LTMSLK-------------PQQQQQQQQQQQQQQQQQQQQQQQPPP 191 L L+ PQQQQQ Q Q+Q QQ Q +Q PP Sbjct: 4197 LRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPP 4242 Score = 36.2 bits (82), Expect = 0.21 Identities = 50/201 (24%), Positives = 69/201 (34%), Gaps = 25/201 (12%) Query: 51 PSAAPPPPGP-GPPP--SRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVL 107 P PP P PPP S S PP AS + P L L P + Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP---EALHLSRPLEESPLS 495 Query: 108 LLPLASPGAPPAAPTRASPL--GARASPPRSGVSLARPAPGCPRPACEPVYGPLTMS-LK 164 P SP +PP + SPL + P S S A P P P P+ P S L Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555 Query: 165 PQQQQ------------QQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASP---- 208 P ++ ++ ++ PPP A+ + P L+ P Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615 Query: 209 AAAPSPSSSSVSSSSATAPSS 229 +P P +S +S +P S Sbjct: 616 PLSPPPEASRLSPPPEDSPMS 636 Score = 35.4 bits (80), Expect = 0.36 Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 30/90 (33%) Query: 53 AAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVL-LLPL 111 +APPP P PPPS + P++ P P V L PL Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASP-------------------------PTEPLVELPTEPL 4941 Query: 112 ASPGAPPAAPTRASPLGA----RASPPRSG 137 A P P P +SP A RA PP G Sbjct: 4942 AEPPVPSPLPLASSPESARPKPRARPPEEG 4971 Score = 35.0 bits (79), Expect = 0.47 Identities = 77/364 (21%), Positives = 113/364 (31%), Gaps = 63/364 (17%) Query: 929 PKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTP 988 P PS T +P + S G QP +T P P +P QP P P Sbjct: 2198 PYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP-----------PGTPRHQPSTPDPFL- 2245 Query: 989 MPVNQAKTYRAVPNMPQQRQDQHHQSAMMHP--------ASAAGPPIAATPPAYSTQYVA 1040 P + AVP P + + + P + A+ P+Y + Sbjct: 2246 KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLG 2305 Query: 1041 Y--SPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAH 1098 + SP H+ + + P V+ + A + P + PGL G Sbjct: 2306 FVDSPSS------GTHLGGLELKTPDVFKAPLTPRASQVEPQS---PGL--------GLR 2348 Query: 1099 EQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQ 1158 Q P + PS GS YA P T P P P+ + Sbjct: 2349 PQEP-----PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL 2403 Query: 1159 SQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSF 1218 S SP Q SP + P+P +TP + P + Sbjct: 2404 PSDPFSRVPASPQSQSSSQ--------SPLTPRPLSAEAFCPSP--VTPRFQSPDPYSRP 2453 Query: 1219 PAAQQTVFTIHPSHVQPAYTNPPHMAHV--PQAHVQSG------MVPSHPTAHAPMMLMT 1270 P+ Q+ P H +P PP +A AH G +P+ P + + Sbjct: 2454 PSRPQSRDPFAPLH-KPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512 Query: 1271 TQPP 1274 QPP Sbjct: 2513 GQPP 2516 Score = 34.7 bits (78), Expect = 0.62 Identities = 57/250 (22%), Positives = 83/250 (33%), Gaps = 60/250 (24%) Query: 513 SPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSS------RPPSR 566 SP +G+P S + P S S + ++ + P P P P S PP+ Sbjct: 892 SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951 Query: 567 YQSGPNSLP-----------PRAATPTRPPSRPPSRPS-----------RPPSHPSAHGS 604 G P P AA P PP + PPS S G Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP 1011 Query: 605 PAPVSTMPKRMSSEGPPRMSPKAQRH--PRNHRVSAGRGSISSGLEFVSHNPPSEAATPP 662 +P+ P PP+ SP Q P+N +PPS+ + P Sbjct: 1012 ASPILMEPL------PPQCSPLLQHSLVPQN-------------------SPPSQCSPPA 1046 Query: 663 VARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAM 722 + + PS + V GV + H + + + P P L +P+ + Sbjct: 1047 LPLSVPSPLSPIGKVVGVSD-EAELHEMETEKVSE----PECPALEPSATSPLPSPMGDL 1101 Query: 723 PIPAASPTPA 732 PA SP PA Sbjct: 1102 SCPAPSPAPA 1111 Score = 34.3 bits (77), Expect = 0.81 Identities = 57/253 (22%), Positives = 84/253 (33%), Gaps = 63/253 (24%) Query: 46 APGPYPSAAPP--PPGPGPPPSRQ----SSPPSASDC------FGSNGNGGGAFRPGSRR 93 +P PS +P PP P PPP ++PP+ S FG+ G+ Sbjct: 918 SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSD--------- 968 Query: 94 LLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPA-- 151 P P +L P A T P+ PP G + +P P Sbjct: 969 ------PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022 Query: 152 -CEPVYGPLTMSLKPQQQQQQQ------------------------QQQQQQQQQQQQQQ 186 C P+ L SL PQ Q + + + + ++ Sbjct: 1023 QCSPL---LQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079 Query: 187 QQPPPA---AANVRKPGGSGLLASPAAAPSPSSSSVSS-SSATAPSSVVAATSGGGRPGL 242 + PA +A P G L+ PA +P+P+ S TAP + A PG Sbjct: 1080 EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQ 1139 Query: 243 GRGRNSN--KGLP 253 G ++ KG P Sbjct: 1140 TPGSLASELKGSP 1152 Score = 34.3 bits (77), Expect = 0.81 Identities = 48/201 (23%), Positives = 71/201 (35%), Gaps = 15/201 (7%) Query: 45 AAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPF 104 A P P+ A G G P + S + D G + + G G P Sbjct: 3137 ATPKVEPAPAANSLGLGLKPGQ--SMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAH 3194 Query: 105 VVLLLPLASPGAPPAAPTRASPLGARA---SPPRSGVSLARPAPGCPRPACEPVYGPLTM 161 ++ PL+ PG GA P SG L + + L Sbjct: 3195 LLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDL-- 3252 Query: 162 SLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSS 221 L+ ++++ Q++QQ Q Q QQQQQ + + PG PA A S S Sbjct: 3253 -LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPG-------PAQAMSLPHEGSSP 3304 Query: 222 SSATAPSSVVAATSGGGRPGL 242 S A + + +G +PGL Sbjct: 3305 SLAGSQQQLSLGLAGARQPGL 3325 Score = 33.9 bits (76), Expect = 1.1 Identities = 15/23 (65%), Positives = 19/23 (82%) Query: 162 SLKPQQQQQQQQQQQQQQQQQQQ 184 +L + + +QQQQQQQQQQQQQQ Sbjct: 3590 NLMAEYRNKQQQQQQQQQQQQQQ 3612 Score = 33.5 bits (75), Expect = 1.4 Identities = 16/32 (50%), Positives = 21/32 (65%) Query: 168 QQQQQQQQQQQQQQQQQQQQQPPPAAANVRKP 199 + + +QQQQQQQQQQQQQQ A + + P Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSP 3625 Score = 33.5 bits (75), Expect = 1.4 Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 7/94 (7%) Query: 554 SPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPS----RPSRPPSHPSAHGSPAPVS 609 SP P P ++ Y + +A P PS PPS P+ PP+ P P++ Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942 Query: 610 TMPKRMSSEGPPRMSPKAQR-HPRNHRVSAGRGS 642 P + S P SP++ R PR G S Sbjct: 4943 EPP--VPSPLPLASSPESARPKPRARPPEEGEDS 4974 Score = 33.1 bits (74), Expect = 1.8 Identities = 46/186 (24%), Positives = 59/186 (31%), Gaps = 19/186 (10%) Query: 46 APGPYPSAAPPPP-----GPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGP 100 +P P S PPP P P SR S PP S A P L+ L Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT-SPPPEDSPASPPPEDSLMSLPLE 721 Query: 101 PRPFVVLLLPLASPGAPPAAPTRASP-LGARASPPRSGVSLARP--APGCPRPACEPVYG 157 P LLPL P P P P L R P P +P P P Sbjct: 722 ESP----LLPL--PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE 775 Query: 158 PLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSS 217 + P++ Q + Q ++ P +P S + P +P P S Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP----QTEEPHLSPVPEEPCLSPQPEES 831 Query: 218 SVSSSS 223 +S S Sbjct: 832 HLSPQS 837 Score = 33.1 bits (74), Expect = 1.8 Identities = 23/80 (28%), Positives = 29/80 (36%) Query: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSS 218 L + +QQQQQQQQQQQQQQ P + + K G L P Sbjct: 3591 LMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGG 3650 Query: 219 VSSSSATAPSSVVAATSGGG 238 + P + GG Sbjct: 3651 QAGGLRLTPGGMALPGQPGG 3670 Score = 32.7 bits (73), Expect = 2.3 Identities = 67/282 (23%), Positives = 98/282 (34%), Gaps = 45/282 (15%) Query: 558 SPSSRPPSRYQSGPNSLPPRAATPTRP--------PSRPPSRPSRPPSHPSAHGSPAPVS 609 +P + PP +G + PP +RP + PP P PS P P S Sbjct: 2192 APPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPS 2251 Query: 610 ----TMPKRMSSEG----PPRMSP----KAQRHPRNHRVSAGRGSISSG---LEFV---- 650 +P+ G P +SP ++++ + G S S G L FV Sbjct: 2252 LDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPS 2311 Query: 651 --SHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLA 708 +H E TP V + +P S V P L + P P Q + PS P + Sbjct: 2312 SGTHLGGLELKTPDVFK-APLTPRASQVEPQSPGLGLRPQEP-PPAQALAPSPPSHPDIF 2369 Query: 709 SPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKD--SRLQDQRQNSPAG----- 761 P + T+ A P P P P S A+ P S D SR+ Q+ + Sbjct: 2370 RPGS---YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426 Query: 762 ----NKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKK 799 + E P+ +P F + P + R L K Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468 Score = 32.0 bits (71), Expect = 4.0 Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 14/115 (12%) Query: 97 LGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVY 156 LGG P P L L + P P +P GA ++ P G P P P+ EP Sbjct: 4263 LGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQ---EP-- 4317 Query: 157 GPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAA 211 +P Q Q + Q P P + P G SPAAA Sbjct: 4318 ------KRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR---VSPAAA 4363 Score = 31.6 bits (70), Expect = 5.2 Identities = 60/311 (19%), Positives = 104/311 (33%), Gaps = 36/311 (11%) Query: 768 PNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDF-------RLQPSSTSESMDQLLN 820 P E P + A ++ V+ E + ++++ + + +++P+ + S+ L Sbjct: 3096 PEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLK 3155 Query: 821 KNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSG------SSKPNSPSISPSILSNTEH 874 + SRD S+ E +S T G + P S S+L E Sbjct: 3156 PGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFEL 3215 Query: 875 KRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR---KSTLNPNAKEFNPRSFSQPKP 931 + G G PA ++ DK E A ++ + L KE + Q Sbjct: 3216 ESGALTLPGG-----PAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQ--QLSA 3268 Query: 932 STTPTSPRPQAQPSPSMVGHQQPTPVYT------QPVCFAPNMMYPVPVSPGVQPLYPIP 985 P + Q Q S++ P + P + ++ QP P P Sbjct: 3269 QLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQP 3328 Query: 986 MTP-MPVNQAKTYRAVPNMPQQRQD------QHHQSAMMHPASAAGPPIAATPPAYSTQY 1038 + P P A R P+M QH A + P ++ P ++ P Sbjct: 3329 LMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPS 3388 Query: 1039 VAYSPQQFPNQ 1049 + PQQ Q Sbjct: 3389 MCMKPQQLAMQ 3399 Score = 31.6 bits (70), Expect = 5.2 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 9/65 (13%) Query: 159 LTMSLKPQQQQQQQQQ---------QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPA 209 L L+ QQQQQQQQQ QQQQQ Q Q P + P L Sbjct: 3730 LAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQ 3789 Query: 210 AAPSP 214 +P P Sbjct: 3790 LSPQP 3794 Score = 30.8 bits (68), Expect = 8.9 Identities = 52/203 (25%), Positives = 72/203 (35%), Gaps = 29/203 (14%) Query: 55 PPPPGPG-----PPPSRQ--SSPPSASDCFGSNGNGGGAFRPGSRR-------LLGLGGP 100 P PG G PPP++ SPPS D FRPGS L P Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHPD----------IFRPGSYTDPYAQPPLTPRPQP 2389 Query: 101 PRPFVVLLLPLASPGAPPAAPTRASPLGARAS-PPRSGVSLARPAPGCPRPACEPVYGPL 159 P P LP S + P + ASP +S P + L+ A CP P P Sbjct: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA-FCPSPVTPRFQSPD 2448 Query: 160 TMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-PSSSS 218 S P + Q + + + Q + A + G+G PAA P+ P+ Sbjct: 2449 PYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG--GFPAALPAGPAGEL 2506 Query: 219 VSSSSATAPSSVVAATSGGGRPG 241 + + P + V + G G Sbjct: 2507 HAKVPSGQPPNFVRSPGTGAFVG 2529 Score = 30.8 bits (68), Expect = 8.9 Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 8/107 (7%) Query: 548 GGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAP 607 GG P P P R Q GP LP + P P P+ PPS P P+ Sbjct: 4264 GGFPGPQTGPLQELGAGPRPQ-GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQ 4322 Query: 608 VSTMPKRMSSEG--PPRM--SPKAQ---RHPRNHRVSAGRGSISSGL 647 + + ++ +E PP +PK Q P RVS ++ L Sbjct: 4323 LPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTL 4369 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 74.3 bits (181), Expect = 7e-13 Identities = 127/528 (24%), Positives = 179/528 (33%), Gaps = 108/528 (20%) Query: 654 PPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRS---PRQNSIGN-TPSGPVLAS 709 P ++ ATP SPS G S + G SP S P + + TP P Sbjct: 1519 PWNQGATPAYGAWSPSVG--SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPG 1576 Query: 710 PQAGIIPTEAVAMPIPAASPT-PA-SPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIK 767 P + IP+ AM P+ SPT PA P S TP S + SP+ + + Sbjct: 1577 PSSPYIPSPGGAMS-PSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPN 1635 Query: 768 PNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEK 827 + TSPS+S SP S P+S S S Sbjct: 1636 YSPTSPSYSPT-----SPSYS-------------------PTSPSYS------------- 1658 Query: 828 SRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQT 887 P++ + S + TS S P SPS SP+ S + TS Sbjct: 1659 ----------PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1708 Query: 888 SSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPS 945 +SP+ + S +P + ++P S +S P+ TPTSP S Sbjct: 1709 TSPSYSPTSPSYSPTSPSYSPTSPS-YSPTSPSYSPTSPNYSPTSPNYTPTSP----SYS 1763 Query: 946 PSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQ 1005 P+ + +P YT +PN P SP P P P + R P P Sbjct: 1764 PTSPSYSPTSPNYTPT---SPNYS---PTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPT 1817 Query: 1006 QRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHV 1065 S S P T P+YS Y+P P P Y P Sbjct: 1818 YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPT---SPKYSPTSPK- 1873 Query: 1066 YSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAIS 1125 YSP PT+ S + +Y T++ P P TSP Sbjct: 1874 YSP---------TSPTY------SPTTPKYSPTSPTYS----PTSPVYTPTSP------- 1907 Query: 1126 TGSLAQQYAHPNATLHPHTPHPQPSA---TPTGQQQSQHGGSHPAPSP 1170 +Y+ + T P +P P++ +PT + S + + P SP Sbjct: 1908 ------KYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSP 1949 Score = 71.6 bits (174), Expect = 5e-12 Identities = 103/456 (22%), Positives = 162/456 (35%), Gaps = 56/456 (12%) Query: 848 SSSNCTSGSSKPNSPSISPSILS-NTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAA 906 S+++ SG S SP+ SP+ S + P + S G SP+ E + Sbjct: 1549 SAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPG-GAMSPSYSPTSPAYEPRSPGG 1607 Query: 907 EQVRKSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVY--TQPV 962 + + +P + ++P S +S P+ +PTSP SP+ + +P Y T P Sbjct: 1608 YTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSP----SYSPTSPSYSPTSPSYSPTSP- 1662 Query: 963 CFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASA 1022 ++P P SP P P P + P P S S Sbjct: 1663 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1722 Query: 1023 AGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTH 1082 P + T P+YS +YSP P+Y P+ Y+P + + Sbjct: 1723 TSPSYSPTSPSYSPTSPSYSPTS----------PNYSPTSPN-YTPTSPSYSPTSPSYSP 1771 Query: 1083 AQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHP 1142 P +S + T Y+ P P TSPS+ + +Y + T P Sbjct: 1772 TSPNYTPTSPN----YSPTSPSYS-PTSPSYSPTSPSY------SPSSPRYTPQSPTYTP 1820 Query: 1143 HTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTP 1202 +P PS+ ++ + P+ SP + SP+ +PT Sbjct: 1821 SSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKY---------SPTS 1871 Query: 1203 PSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYT------NPPHMAHVPQAHVQSGMV 1256 P +P S T SP + P T T P+ P YT +P + P + S Sbjct: 1872 PKYSPTSPTYSP--TTPKYSPTSPTYSPT--SPVYTPTSPKYSPTSPTYSPTSPKYSPTS 1927 Query: 1257 PSH-PTAHAPMMLMTTQP---PGGPQAALAQSALQP 1288 P++ PT+ T P P P +L A+ P Sbjct: 1928 PTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISP 1963 Score = 69.7 bits (169), Expect = 2e-11 Identities = 116/500 (23%), Positives = 174/500 (34%), Gaps = 67/500 (13%) Query: 495 PPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVP--W 552 P G + + W G +P G S S+ S T + F+P++ SD + G W Sbjct: 1509 PMGGISPAMTPWNQGA--TPAYGA-WSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAW 1565 Query: 553 -PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTM 611 P+P S P S Y P + +PT P P S P PS SP S Sbjct: 1566 SPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSY--SPTSPSYS 1623 Query: 612 PKRMS-SEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSG 670 P S S P SP + S++P S + +P SP+ Sbjct: 1624 PTSPSYSPTSPNYSPTSP----------------------SYSPTSPSYSPTSPSYSPTS 1661 Query: 671 GTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPI-PAASP 729 ++S SP ++ P SP +P+ P + PT P P+ SP Sbjct: 1662 PSYSPTSPSYSPTSP-SYSPTSP-----SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1715 Query: 730 T-PASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVS 788 T P+ ++ + +P+S + SP + + TSPS+S + SP Sbjct: 1716 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPT-SPSYSPTSP 1774 Query: 789 EHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENS 848 + + + S TS S PS+ + Sbjct: 1775 NYTPTSPNYSPTSPSY----SPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSP 1830 Query: 849 SSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQ 908 S + TS P SPS SPS PE T + S + K + + Sbjct: 1831 SYSPTSPKYTPTSPSYSPS---------SPEYTPTSPKYSPTSPKYSPTSPKYSPTS--- 1878 Query: 909 VRKSTLNPNAKEFNPRS--FSQPKPSTTPTSPR---PQAQPSPSMVGHQQPTPVYTQPVC 963 T +P +++P S +S P TPTSP+ SP+ + +P Y+ Sbjct: 1879 ---PTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPT-- 1933 Query: 964 FAPNMMYPVPVSPGVQPLYP 983 +P P SPG P P Sbjct: 1934 -SPKGSTYSPTSPGYSPTSP 1952 Score = 57.8 bits (138), Expect = 7e-08 Identities = 82/349 (23%), Positives = 129/349 (36%), Gaps = 40/349 (11%) Query: 912 STLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYP 971 S + P A F+P + S + SP P+P G P+ Y A + Y Sbjct: 1537 SGMTPGAAGFSPSAASDASGFSPGYSPA--WSPTPGSPGSPGPSSPYIPSPGGAMSPSYS 1594 Query: 972 VPVSPGVQPLYPIPMTPMPVNQAKTYRAV-PNMPQQRQDQHHQSAMMHPASAAGPPIAAT 1030 P SP +P P TP + + T + P P + S S P + T Sbjct: 1595 -PTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPT 1653 Query: 1031 PPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSS 1090 P+YS +YSP P P Y P YSP P+++ P S Sbjct: 1654 SPSYSPTSPSYSPTSPSYSPTS---PSYSPTSPS-YSPT---------SPSYS-PTSPSY 1699 Query: 1091 SATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPS 1150 S T ++ T Y+ P P TSPS+ + Y+ + + P +P+ P+ Sbjct: 1700 SPTS-PSYSPTSPSYS-PTSPSYSPTSPSY------SPTSPSYSPTSPSYSPTSPNYSPT 1751 Query: 1151 ATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASN 1210 + + + P+ SP + + SP +PT PS +P S Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSY---------SPTSPSYSPTSP 1802 Query: 1211 TQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSH 1259 + SP + Q +T PS P+Y +P ++ P + + PS+ Sbjct: 1803 SYSPSSPRYTPQSPTYT--PS--SPSY-SPSSPSYSPTSPKYTPTSPSY 1846 Score = 41.6 bits (96), Expect = 0.005 Identities = 51/205 (24%), Positives = 68/205 (33%), Gaps = 11/205 (5%) Query: 44 GAAPGPYPSAAPPPPGPGPP-PSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPR 102 G +PG P+ +P P PG P PS P S A+ P R G P Sbjct: 1556 GFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEP---RSPGGYTPQS 1612 Query: 103 PFVVLLLPLASPGAPPAAPT--RASPLGARASPPRSGVSLARPAPGCPRPACEPV---YG 157 P P SP +P +PT SP SP S P+ P+ P Y Sbjct: 1613 PSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1672 Query: 158 PLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQP--PPAAANVRKPGGSGLLASPAAAPSPS 215 P + S P P P + + S SP+ +P+ Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1732 Query: 216 SSSVSSSSATAPSSVVAATSGGGRP 240 S S +S S + S + TS P Sbjct: 1733 SYSPTSPSYSPTSPNYSPTSPNYTP 1757 Score = 38.9 bits (89), Expect = 0.033 Identities = 56/198 (28%), Positives = 69/198 (34%), Gaps = 21/198 (10%) Query: 38 SGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL 97 S GG A P+ A P G P P A+ S + F PG Sbjct: 1508 SPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPG----YSP 1563 Query: 98 GGPPRPFVVLLLPLASPGAP-PAAPTRASPLGARASPPRSGVSLARP--APGCPRPACEP 154 P P SPG+P P++P SP GA SP S S A +PG P P Sbjct: 1564 AWSPTP--------GSPGSPGPSSPYIPSPGGA-MSPSYSPTSPAYEPRSPGGYTPQ-SP 1613 Query: 155 VYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQP--PPAAANVRKPGGSGLLASPAAAP 212 Y P + S P P P + + S SP+ +P Sbjct: 1614 SYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1673 Query: 213 -SPSSSSVSSS-SATAPS 228 SPS S S S S T+PS Sbjct: 1674 TSPSYSPTSPSYSPTSPS 1691 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 72.8 bits (177), Expect = 2e-12 Identities = 81/249 (32%), Positives = 99/249 (39%), Gaps = 33/249 (13%) Query: 39 GRGGGGAAPGPY--PSAAPPP--------PGPGPP-----PSRQSSPPSASDCFGSNGNG 83 G+G GG PGP P+ AP P P PP S SS +AS S+ + Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 84 GGAFRPGSRRLLGLGGPPRPFVVLLLPLASPG-APPAAPTRASPLGARASPPRSGVSL-- 140 F P S+ L P L + P P+ P++A PP G L Sbjct: 396 ASPF-PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454 Query: 141 --ARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ-----PPPAA 193 A P P P + P + QQQQQQQQQQQQQQQQQQQ PPP A Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA 514 Query: 194 ANVRKPGGSGLLASPAAAPSPSSSSV---SSSSATAP---SSVVAATSGGGRPGLGRGRN 247 GGS A P A SPS S+ A P S V + +G P + N Sbjct: 515 FPHPLEGGSSHHAHPYAM-SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573 Query: 248 SNKGLPQST 256 S+ Q + Sbjct: 574 SSSSTSQGS 582 Score = 64.3 bits (155), Expect = 7e-10 Identities = 174/829 (20%), Positives = 259/829 (31%), Gaps = 150/829 (18%) Query: 445 AEEIESSAQYKARVA------LENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQ 498 AE+ +A+ KARV + RSEE + + SE T+ + +P Q Sbjct: 47 AEKSRQTAK-KARVEEASTPKVNKQGRSEE-----ISESESEETNAPKKTKTEQELPRPQ 100 Query: 499 RNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGV-------- 550 ++ S N P +RSTS S ++P S + + G+ Sbjct: 101 SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTS-PSIYSPGSVENDSDSSSGLSQGPARPY 159 Query: 551 -------PWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRP--PSRPSRPPSHPSA 601 P P P S +P + ++ P+ P P PP+ + P PP HP Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL 219 Query: 602 H-GSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT 660 + G V + P G S + H S+SS S PP++ T Sbjct: 220 YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS--SGASGAPPTKPPT 277 Query: 661 PPVA----RTSPSGGTWSSVVSGV---PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQA- 712 PV ++P + V + P L P + SP +G P L SP A Sbjct: 278 TPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP--PGLGAQPLPGHLPSPHAM 335 Query: 713 ----GIIPTEAVAMPIPAASPTPASPASNRAVTP------SSEAKDSRLQDQRQNSPAGN 762 G +P P A SP PAS+ A P SS + S +S + + Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 763 KENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKN 822 ++ PS+ + S VS + QPS S+++ Sbjct: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKY-----------TQPSLPSQAV------- 437 Query: 823 REGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTS 882 S P P +L+N+ GP S Sbjct: 438 --------------------------------WSQGPPPPPPYGRLLANSNAHPGPFPPS 465 Query: 883 QGVQ-TSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQ 941 G Q T+ P ++++ +Q ++ N S P P P Sbjct: 466 TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN----SGPPP--------PG 513 Query: 942 AQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVP 1001 A P P G + P +P++ P PG L P P +Q +A P Sbjct: 514 AFPHPLEGGSSH----HAHPYAMSPSLGSLRPYPPGPAHL------PPPHSQVSYSQAGP 563 Query: 1002 NMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQ 1061 N P + S+ S P + P+ Q +P FP P V + Sbjct: 564 NGPPVSSSSNSSSS----TSQGSYPCSHPSPSQGPQ---GAPYPFPPVPTV-------TT 609 Query: 1062 HPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLP-YNKETSPSF 1120 S VI A A A P YG + Y P Y + PSF Sbjct: 610 SSATLSTVIATVASSPAGYKTASP----PGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF 665 Query: 1121 YFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQ 1180 G T P +P P P P +P A Q Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQ 725 Query: 1181 ALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIH 1229 Q+ + Y +P PP+ +P+ + A+Q F H Sbjct: 726 I-----KQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKH 769 Score = 63.2 bits (152), Expect = 2e-09 Identities = 132/626 (21%), Positives = 202/626 (32%), Gaps = 99/626 (15%) Query: 747 KDSR-LQDQRQNSPAGNKENIKPN-ETSP---SFSKAENKGISPVVSEHRKQIDDLKKFK 801 KDS ++ R+ G +E ++ SP S S ++ K + + ++++ K Sbjct: 7 KDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPK 66 Query: 802 NDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNS 861 + + + SES + N ++ + ++L + + PS DS G S + Sbjct: 67 VNKQGRSEEISESESEETNAPKKTKTEQELPRPQ-SPSDLDSL---------DGRSLNDD 116 Query: 862 PSISPSILSNTEHKRGPEVTSQG-VQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKE 920 S P + P + S G V+ S + S P++ Sbjct: 117 GSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTP 176 Query: 921 FNPRSFSQPKPSTTPTSPRPQAQPSPSMV---------GHQQPTPVYTQPVCFAPNM--- 968 P + +P PS TPT +P S + H Q P T V P M Sbjct: 177 RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236 Query: 969 ---MYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASA--- 1022 P +P P TP+ V+ + A P P P + Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296 Query: 1023 AGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVP--HYQSQ-----------------HP 1063 P + P + SP QPL H+P H Q P Sbjct: 297 VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP 356 Query: 1064 HVYSPVIQGNARMMAPP--------THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKE 1115 H P ++ APP + + SSS++ + A A P P++ Sbjct: 357 HSLPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413 Query: 1116 TSPSFYFAISTGSLAQQYAHPNATLH--------PHTP----------HPQPSATPTGQQ 1157 S +S + +Y P+ P P HP P TG Q Sbjct: 414 PPTS----LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469 Query: 1158 QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTP-ASNTQSPQN 1216 + H P + HHQ Q Q QQQ +H P PP P S + Sbjct: 470 STAHP---PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH 526 Query: 1217 SFP-AAQQTVFTIHPSHVQPAYTNPPH------MAHVPQAHVQSGMVPSHPTAHAPMMLM 1269 + P A ++ ++ P PA+ PPH A V S S T+ Sbjct: 527 AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586 Query: 1270 TTQPPGGPQAALAQSALQPIPVSTTA 1295 P GPQ A P+P TT+ Sbjct: 587 HPSPSQGPQG--APYPFPPVPTVTTS 610 Score = 60.1 bits (144), Expect = 1e-08 Identities = 152/742 (20%), Positives = 261/742 (35%), Gaps = 120/742 (16%) Query: 510 RQNSPRMGQPGSGSMP------SRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRP 563 +Q+ G P G+ P S +H +P+ GS + P P+ P P S+ Sbjct: 501 QQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS----LRPYPPGPAHLPPPHSQV 556 Query: 564 PSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRM 623 S Q+GPN P +++ + S S+ S P SHPS P +G P Sbjct: 557 -SYSQAGPNGPPVSSSSNS---SSSTSQGSYPCSHPSPSQGP------------QGAPYP 600 Query: 624 SPKAQRHPRNHRVSAGRGSISSGLEFVSHNPP-----SEAATPPVARTSPSGGTWSSVVS 678 P V+ ++S+ + V+ +P S PP + +PS G + + Sbjct: 601 FPPVPT------VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATP 654 Query: 679 -GVPRLSPKTHRPRSPRQNSIGNTPSGPVL---ASPQAGIIPTE-AVAMPIPAASPTPAS 733 G SP + R +P + P+GP SP G P A +P+ P PA+ Sbjct: 655 PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714 Query: 734 PASNRAVTPSS---------EAKDSRLQDQRQNSPAGNKENIKPNETSPS--FSKAENKG 782 PAS ++ + E +S + R SP ++ P+ S S F+K ++G Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV-PSHASQSARFNKHLDRG 773 Query: 783 ISPVVSEH------------RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRD 830 + +K+ D ++K + + + E + RE EK R+ Sbjct: 774 FNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKER-----EREREREKERE 828 Query: 831 LIKDK-IEPSAKDSFIENSSSNCTSGSSKPNSPSISP-SILSNTEHKRGPEVTSQGVQTS 888 K++ +E S K + + C S P+ P P S ++ GP+ + ++T Sbjct: 829 REKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPD--TPALRTL 886 Query: 889 SPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFN-PRSFSQPKPSTTPTSPRPQAQPSPS 947 S + + V ++P +N P +S + + Sbjct: 887 SEYARPHVMSPGNRNHPF-YVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDR 945 Query: 948 MVGHQQPTPVYTQPVCFAPNM-MYPVP------VSPGVQPLYPIPMTPMPVNQAKTYRAV 1000 + + P +P+ P + P P + PG L+P P P + A+ Sbjct: 946 LKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLAL 1005 Query: 1001 PNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQS 1060 P R D + + A ++ + A ++ PH+ Sbjct: 1006 AAGPALRPDMSYAERL------------AAERQHAERVAALGNDPLARLQMLNVTPHHH- 1052 Query: 1061 QHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSF 1120 QH H++S + H Q + ++SA+ + + + ++PY T P+ Sbjct: 1053 QHSHIHSHL----------HLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPN- 1101 Query: 1121 YFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQ 1180 L H N L Q A P + A +Q Q+A+ Sbjct: 1102 -------PLLPHPLHENEVL-----RHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAE 1149 Query: 1181 ALHLASPQQQSAIYHAGLAPTP 1202 LA QQQ H L P Sbjct: 1150 LQRLALEQQQWLHAHHPLHSVP 1171 Score = 58.9 bits (141), Expect = 3e-08 Identities = 108/475 (22%), Positives = 159/475 (33%), Gaps = 72/475 (15%) Query: 884 GVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK-----EFNPRSFSQPKPSTTPTS- 937 GV TSS K EK + KK E+ +N + E + PK + T Sbjct: 37 GVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQEL 96 Query: 938 PRPQAQPSPSMV--------GHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPM 989 PRPQ+ + G P + +P++ P V + P Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP- 155 Query: 990 PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQ 1049 A+ Y P P Q S P ++ P + TP Y ++P + P Sbjct: 156 ----ARPYHPPPLFPPSPQPP--DSTPRQPEASFEPHPSVTPTGY------HAPMEPPTS 203 Query: 1050 PLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPK 1109 + Q P HP +Y G + PP + G +SS +Q + P Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGV--LSGPPMGPKGGGAASSVGGPNGGKQ----HPPPT 257 Query: 1110 LPYNKETS------PSFYFAISTGSLAQQYAHPNATLHPHTPH--PQPSATPTGQQQSQH 1161 P + +S P+ G A P A TP+ P P+ P + Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 1162 GGSHPAPSPVQ-HHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQ-SPQNSFP 1219 G P P H Q + P + LAP+P S+ PAS++ +P FP Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKG---PTLAPSPHSLPPASSSAPAPPMRFP 374 Query: 1220 -------------AAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPM 1266 ++ + + P A + PH P + S P + P Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434 Query: 1267 MLMTTQ-----PPGGPQAALAQSALQPIPVST----TAHFPYMTHPSVQAHHQQQ 1312 + +Q PP G A + + P P ST TAH P TH HH QQ Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH----HHHQQ 485 Score = 56.2 bits (134), Expect = 2e-07 Identities = 171/828 (20%), Positives = 268/828 (32%), Gaps = 151/828 (18%) Query: 462 NDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQ--- 518 +D ++E+ + TA + E +N + R+ E+ S N+P+ + Sbjct: 43 SDGKAEKSRQTAKKARVEEASTPKVNKQG--------RSEEISESESEETNAPKKTKTEQ 94 Query: 519 --PGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPP 576 P S + N + SD R ++ + SPS P ++ +S Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQD----NRSTSPSIYSPGSVENDSDSSSG 150 Query: 577 RAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKR--MSSEGPPRMSPKAQRHPRNH 634 + P RP PP P SP P + P++ S E P ++P P Sbjct: 151 LSQGPARPYHPPPLFPP----------SPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP 200 Query: 635 RVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPR 694 S + PP A PP + P GGT V+SG P + PK S Sbjct: 201 PTSR-----------MFQAPPG--APPPHPQLYP-GGT-GGVLSGPP-MGPKGGGAAS-- 242 Query: 695 QNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQ 754 S+G G P I + + A P P P +P + PS+ Sbjct: 243 --SVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP-PTTPVGGGNL-PSAP--------- 289 Query: 755 RQNSPAGNKENIKPN-ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSE 813 P N ++ PN P+ N SP + L P + + Sbjct: 290 ----PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPS--------PHAMGQ 337 Query: 814 SMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTE 873 M L +G + PS S + SS P P P S++ Sbjct: 338 GMGGLPPGPEKGPT--------LAPSPH--------SLPPASSSAPAPPMRFPYSSSSSS 381 Query: 874 HKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPST 933 +S ++SP A Q S P SF P + Sbjct: 382 SAAASSSSSSSSSSASPF-------------PASQALPSY---------PHSFPPPTSLS 419 Query: 934 TPTSPRPQAQPS-PSMVGHQQ---PTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPM 989 P QPS PS Q P P Y + + + P P S G Q Sbjct: 420 VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST-----AHP 474 Query: 990 PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYS--TQYVAYSPQQFP 1047 PV+ + QQ+Q Q Q H ++ PP A P + + A+ P Sbjct: 475 PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534 Query: 1048 NQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTH----- 1102 + ++ P + P +S V A PP + SSS+T G++ +H Sbjct: 535 SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN--SSSSTSQGSYPCSHPSPSQ 592 Query: 1103 ----AMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQ 1158 A Y P +P +S + I+T + + + A+ P+ + + +P + Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTASPPGPPPYGKRAPSPGAYKT 651 Query: 1159 SQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPT--PPSMTPASNTQSPQN 1216 + G P P + +P + G +P P + P S T P Sbjct: 652 ATPPGYKPGSPP----------SFRTGTPPG-----YRGTSPPAGPGTFKPGSPTVGPGP 696 Query: 1217 SFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHA 1264 PA + ++ P PA P + Q + P P A Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPA 744 Score = 48.9 bits (115), Expect = 3e-05 Identities = 49/156 (31%), Positives = 58/156 (37%), Gaps = 15/156 (9%) Query: 8 PRSPAVATESRRFAA-----ARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGP 62 P P V T S + A P P G +PG Y +A PP PG Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 63 PPS-RQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAP 121 PPS R +PP S G G F+PGS + GP P LP P PPAAP Sbjct: 662 PPSFRTGTPPGYRGT--SPPAGPGTFKPGSPTV--GPGPLPPAGPSGLPSLPP--PPAAP 715 Query: 122 TRASPLGA---RASPPRSGVSLARPAPGCPRPACEP 154 PL A + P + P P P+ P Sbjct: 716 ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751 Score = 40.4 bits (93), Expect = 0.011 Identities = 60/224 (26%), Positives = 73/224 (32%), Gaps = 54/224 (24%) Query: 41 GGGGAAPGPYP------SAAPPPPGPG--PPPSRQSS--------PPSASDCFGSNGNGG 84 GG PY S P PPGP PPP Q S PP +S S+ Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580 Query: 85 GAFRPGSRRLLGLG--GPPRPF----------VVLLLPLASPGAPPAAPTRASPLGARAS 132 G++ P S G G P PF L +A+ + PA ASP G Sbjct: 581 GSY-PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG---- 635 Query: 133 PPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPA 192 PP G P+PG + A P Y P + + PPA Sbjct: 636 PPPYGKRA--PSPGAYKTATPPGYKP-------------GSPPSFRTGTPPGYRGTSPPA 680 Query: 193 AANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSG 236 KPG SP P P + S + P A SG Sbjct: 681 GPGTFKPG------SPTVGPGPLPPAGPSGLPSLPPPPAAPASG 718 Score = 35.4 bits (80), Expect = 0.36 Identities = 69/267 (25%), Positives = 83/267 (31%), Gaps = 48/267 (17%) Query: 38 SGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS---NGNGGGAFRPGSRRL 94 SG G A P P PP P PP S P ++ + S G P SR Sbjct: 149 SGLSQGPARPYHPPPLFPP--SPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMF 206 Query: 95 LGLGGPPRPFV---------VLLLPLASPGAPPAAPTRASPLGARASPP--------RSG 137 G P P VL P P AA + P G + PP SG Sbjct: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266 Query: 138 VSLARPA------------PGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQ 185 S A P P P PA P P + P + Q Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTP-NLPPPPALRPLNNASASPPGLGAQPL 325 Query: 186 QQQPPPAAANVRKPGG--SGLLASPAAAPSPSSSSVSSSSATAP-----------SSVVA 232 P A + GG G P APSP S +SSSA AP SS A Sbjct: 326 PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA 385 Query: 233 ATSGGGRPGLGRGRNSNKGLPQSTISF 259 ++S +++ LP SF Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSF 412 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 72.8 bits (177), Expect = 2e-12 Identities = 81/249 (32%), Positives = 99/249 (39%), Gaps = 33/249 (13%) Query: 39 GRGGGGAAPGPY--PSAAPPP--------PGPGPP-----PSRQSSPPSASDCFGSNGNG 83 G+G GG PGP P+ AP P P PP S SS +AS S+ + Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 84 GGAFRPGSRRLLGLGGPPRPFVVLLLPLASPG-APPAAPTRASPLGARASPPRSGVSL-- 140 F P S+ L P L + P P+ P++A PP G L Sbjct: 396 ASPF-PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454 Query: 141 --ARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ-----PPPAA 193 A P P P + P + QQQQQQQQQQQQQQQQQQQ PPP A Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA 514 Query: 194 ANVRKPGGSGLLASPAAAPSPSSSSV---SSSSATAP---SSVVAATSGGGRPGLGRGRN 247 GGS A P A SPS S+ A P S V + +G P + N Sbjct: 515 FPHPLEGGSSHHAHPYAM-SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573 Query: 248 SNKGLPQST 256 S+ Q + Sbjct: 574 SSSSTSQGS 582 Score = 64.3 bits (155), Expect = 7e-10 Identities = 174/829 (20%), Positives = 259/829 (31%), Gaps = 150/829 (18%) Query: 445 AEEIESSAQYKARVA------LENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQ 498 AE+ +A+ KARV + RSEE + + SE T+ + +P Q Sbjct: 47 AEKSRQTAK-KARVEEASTPKVNKQGRSEE-----ISESESEETNAPKKTKTEQELPRPQ 100 Query: 499 RNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGV-------- 550 ++ S N P +RSTS S ++P S + + G+ Sbjct: 101 SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTS-PSIYSPGSVENDSDSSSGLSQGPARPY 159 Query: 551 -------PWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRP--PSRPSRPPSHPSA 601 P P P S +P + ++ P+ P P PP+ + P PP HP Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL 219 Query: 602 H-GSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT 660 + G V + P G S + H S+SS S PP++ T Sbjct: 220 YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS--SGASGAPPTKPPT 277 Query: 661 PPVA----RTSPSGGTWSSVVSGV---PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQA- 712 PV ++P + V + P L P + SP +G P L SP A Sbjct: 278 TPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP--PGLGAQPLPGHLPSPHAM 335 Query: 713 ----GIIPTEAVAMPIPAASPTPASPASNRAVTP------SSEAKDSRLQDQRQNSPAGN 762 G +P P A SP PAS+ A P SS + S +S + + Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 763 KENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKN 822 ++ PS+ + S VS + QPS S+++ Sbjct: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKY-----------TQPSLPSQAV------- 437 Query: 823 REGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTS 882 S P P +L+N+ GP S Sbjct: 438 --------------------------------WSQGPPPPPPYGRLLANSNAHPGPFPPS 465 Query: 883 QGVQ-TSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQ 941 G Q T+ P ++++ +Q ++ N S P P P Sbjct: 466 TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN----SGPPP--------PG 513 Query: 942 AQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVP 1001 A P P G + P +P++ P PG L P P +Q +A P Sbjct: 514 AFPHPLEGGSSH----HAHPYAMSPSLGSLRPYPPGPAHL------PPPHSQVSYSQAGP 563 Query: 1002 NMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQ 1061 N P + S+ S P + P+ Q +P FP P V + Sbjct: 564 NGPPVSSSSNSSSS----TSQGSYPCSHPSPSQGPQ---GAPYPFPPVPTV-------TT 609 Query: 1062 HPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLP-YNKETSPSF 1120 S VI A A A P YG + Y P Y + PSF Sbjct: 610 SSATLSTVIATVASSPAGYKTASP----PGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF 665 Query: 1121 YFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQ 1180 G T P +P P P P +P A Q Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQ 725 Query: 1181 ALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIH 1229 Q+ + Y +P PP+ +P+ + A+Q F H Sbjct: 726 I-----KQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKH 769 Score = 63.2 bits (152), Expect = 2e-09 Identities = 132/626 (21%), Positives = 202/626 (32%), Gaps = 99/626 (15%) Query: 747 KDSR-LQDQRQNSPAGNKENIKPN-ETSP---SFSKAENKGISPVVSEHRKQIDDLKKFK 801 KDS ++ R+ G +E ++ SP S S ++ K + + ++++ K Sbjct: 7 KDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPK 66 Query: 802 NDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNS 861 + + + SES + N ++ + ++L + + PS DS G S + Sbjct: 67 VNKQGRSEEISESESEETNAPKKTKTEQELPRPQ-SPSDLDSL---------DGRSLNDD 116 Query: 862 PSISPSILSNTEHKRGPEVTSQG-VQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKE 920 S P + P + S G V+ S + S P++ Sbjct: 117 GSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTP 176 Query: 921 FNPRSFSQPKPSTTPTSPRPQAQPSPSMV---------GHQQPTPVYTQPVCFAPNM--- 968 P + +P PS TPT +P S + H Q P T V P M Sbjct: 177 RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236 Query: 969 ---MYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASA--- 1022 P +P P TP+ V+ + A P P P + Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296 Query: 1023 AGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVP--HYQSQ-----------------HP 1063 P + P + SP QPL H+P H Q P Sbjct: 297 VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP 356 Query: 1064 HVYSPVIQGNARMMAPP--------THAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKE 1115 H P ++ APP + + SSS++ + A A P P++ Sbjct: 357 HSLPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413 Query: 1116 TSPSFYFAISTGSLAQQYAHPNATLH--------PHTP----------HPQPSATPTGQQ 1157 S +S + +Y P+ P P HP P TG Q Sbjct: 414 PPTS----LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469 Query: 1158 QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTP-ASNTQSPQN 1216 + H P + HHQ Q Q QQQ +H P PP P S + Sbjct: 470 STAHP---PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH 526 Query: 1217 SFP-AAQQTVFTIHPSHVQPAYTNPPH------MAHVPQAHVQSGMVPSHPTAHAPMMLM 1269 + P A ++ ++ P PA+ PPH A V S S T+ Sbjct: 527 AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586 Query: 1270 TTQPPGGPQAALAQSALQPIPVSTTA 1295 P GPQ A P+P TT+ Sbjct: 587 HPSPSQGPQG--APYPFPPVPTVTTS 610 Score = 60.1 bits (144), Expect = 1e-08 Identities = 152/742 (20%), Positives = 261/742 (35%), Gaps = 120/742 (16%) Query: 510 RQNSPRMGQPGSGSMP------SRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRP 563 +Q+ G P G+ P S +H +P+ GS + P P+ P P S+ Sbjct: 501 QQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS----LRPYPPGPAHLPPPHSQV 556 Query: 564 PSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRM 623 S Q+GPN P +++ + S S+ S P SHPS P +G P Sbjct: 557 -SYSQAGPNGPPVSSSSNS---SSSTSQGSYPCSHPSPSQGP------------QGAPYP 600 Query: 624 SPKAQRHPRNHRVSAGRGSISSGLEFVSHNPP-----SEAATPPVARTSPSGGTWSSVVS 678 P V+ ++S+ + V+ +P S PP + +PS G + + Sbjct: 601 FPPVPT------VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATP 654 Query: 679 -GVPRLSPKTHRPRSPRQNSIGNTPSGPVL---ASPQAGIIPTE-AVAMPIPAASPTPAS 733 G SP + R +P + P+GP SP G P A +P+ P PA+ Sbjct: 655 PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714 Query: 734 PASNRAVTPSS---------EAKDSRLQDQRQNSPAGNKENIKPNETSPS--FSKAENKG 782 PAS ++ + E +S + R SP ++ P+ S S F+K ++G Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV-PSHASQSARFNKHLDRG 773 Query: 783 ISPVVSEH------------RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRD 830 + +K+ D ++K + + + E + RE EK R+ Sbjct: 774 FNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKER-----EREREREKERE 828 Query: 831 LIKDK-IEPSAKDSFIENSSSNCTSGSSKPNSPSISP-SILSNTEHKRGPEVTSQGVQTS 888 K++ +E S K + + C S P+ P P S ++ GP+ + ++T Sbjct: 829 REKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPD--TPALRTL 886 Query: 889 SPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFN-PRSFSQPKPSTTPTSPRPQAQPSPS 947 S + + V ++P +N P +S + + Sbjct: 887 SEYARPHVMSPGNRNHPF-YVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDR 945 Query: 948 MVGHQQPTPVYTQPVCFAPNM-MYPVP------VSPGVQPLYPIPMTPMPVNQAKTYRAV 1000 + + P +P+ P + P P + PG L+P P P + A+ Sbjct: 946 LKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLAL 1005 Query: 1001 PNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQS 1060 P R D + + A ++ + A ++ PH+ Sbjct: 1006 AAGPALRPDMSYAERL------------AAERQHAERVAALGNDPLARLQMLNVTPHHH- 1052 Query: 1061 QHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSF 1120 QH H++S + H Q + ++SA+ + + + ++PY T P+ Sbjct: 1053 QHSHIHSHL----------HLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPN- 1101 Query: 1121 YFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQ 1180 L H N L Q A P + A +Q Q+A+ Sbjct: 1102 -------PLLPHPLHENEVL-----RHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAE 1149 Query: 1181 ALHLASPQQQSAIYHAGLAPTP 1202 LA QQQ H L P Sbjct: 1150 LQRLALEQQQWLHAHHPLHSVP 1171 Score = 58.9 bits (141), Expect = 3e-08 Identities = 108/475 (22%), Positives = 159/475 (33%), Gaps = 72/475 (15%) Query: 884 GVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK-----EFNPRSFSQPKPSTTPTS- 937 GV TSS K EK + KK E+ +N + E + PK + T Sbjct: 37 GVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQEL 96 Query: 938 PRPQAQPSPSMV--------GHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPM 989 PRPQ+ + G P + +P++ P V + P Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP- 155 Query: 990 PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQ 1049 A+ Y P P Q S P ++ P + TP Y ++P + P Sbjct: 156 ----ARPYHPPPLFPPSPQPP--DSTPRQPEASFEPHPSVTPTGY------HAPMEPPTS 203 Query: 1050 PLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPK 1109 + Q P HP +Y G + PP + G +SS +Q + P Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGV--LSGPPMGPKGGGAASSVGGPNGGKQ----HPPPT 257 Query: 1110 LPYNKETS------PSFYFAISTGSLAQQYAHPNATLHPHTPH--PQPSATPTGQQQSQH 1161 P + +S P+ G A P A TP+ P P+ P + Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 1162 GGSHPAPSPVQ-HHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQ-SPQNSFP 1219 G P P H Q + P + LAP+P S+ PAS++ +P FP Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKG---PTLAPSPHSLPPASSSAPAPPMRFP 374 Query: 1220 -------------AAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPM 1266 ++ + + P A + PH P + S P + P Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434 Query: 1267 MLMTTQ-----PPGGPQAALAQSALQPIPVST----TAHFPYMTHPSVQAHHQQQ 1312 + +Q PP G A + + P P ST TAH P TH HH QQ Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH----HHHQQ 485 Score = 56.2 bits (134), Expect = 2e-07 Identities = 171/828 (20%), Positives = 268/828 (32%), Gaps = 151/828 (18%) Query: 462 NDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQ--- 518 +D ++E+ + TA + E +N + R+ E+ S N+P+ + Sbjct: 43 SDGKAEKSRQTAKKARVEEASTPKVNKQG--------RSEEISESESEETNAPKKTKTEQ 94 Query: 519 --PGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPP 576 P S + N + SD R ++ + SPS P ++ +S Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQD----NRSTSPSIYSPGSVENDSDSSSG 150 Query: 577 RAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKR--MSSEGPPRMSPKAQRHPRNH 634 + P RP PP P SP P + P++ S E P ++P P Sbjct: 151 LSQGPARPYHPPPLFPP----------SPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP 200 Query: 635 RVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPR 694 S + PP A PP + P GGT V+SG P + PK S Sbjct: 201 PTSR-----------MFQAPPG--APPPHPQLYP-GGT-GGVLSGPP-MGPKGGGAAS-- 242 Query: 695 QNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQ 754 S+G G P I + + A P P P +P + PS+ Sbjct: 243 --SVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP-PTTPVGGGNL-PSAP--------- 289 Query: 755 RQNSPAGNKENIKPN-ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSE 813 P N ++ PN P+ N SP + L P + + Sbjct: 290 ----PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPS--------PHAMGQ 337 Query: 814 SMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTE 873 M L +G + PS S + SS P P P S++ Sbjct: 338 GMGGLPPGPEKGPT--------LAPSPH--------SLPPASSSAPAPPMRFPYSSSSSS 381 Query: 874 HKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPST 933 +S ++SP A Q S P SF P + Sbjct: 382 SAAASSSSSSSSSSASPF-------------PASQALPSY---------PHSFPPPTSLS 419 Query: 934 TPTSPRPQAQPS-PSMVGHQQ---PTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPM 989 P QPS PS Q P P Y + + + P P S G Q Sbjct: 420 VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST-----AHP 474 Query: 990 PVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYS--TQYVAYSPQQFP 1047 PV+ + QQ+Q Q Q H ++ PP A P + + A+ P Sbjct: 475 PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534 Query: 1048 NQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTH----- 1102 + ++ P + P +S V A PP + SSS+T G++ +H Sbjct: 535 SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN--SSSSTSQGSYPCSHPSPSQ 592 Query: 1103 ----AMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQ 1158 A Y P +P +S + I+T + + + A+ P+ + + +P + Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTASPPGPPPYGKRAPSPGAYKT 651 Query: 1159 SQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPT--PPSMTPASNTQSPQN 1216 + G P P + +P + G +P P + P S T P Sbjct: 652 ATPPGYKPGSPP----------SFRTGTPPG-----YRGTSPPAGPGTFKPGSPTVGPGP 696 Query: 1217 SFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHA 1264 PA + ++ P PA P + Q + P P A Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPA 744 Score = 48.9 bits (115), Expect = 3e-05 Identities = 49/156 (31%), Positives = 58/156 (37%), Gaps = 15/156 (9%) Query: 8 PRSPAVATESRRFAA-----ARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGP 62 P P V T S + A P P G +PG Y +A PP PG Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 63 PPS-RQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAP 121 PPS R +PP S G G F+PGS + GP P LP P PPAAP Sbjct: 662 PPSFRTGTPPGYRGT--SPPAGPGTFKPGSPTV--GPGPLPPAGPSGLPSLPP--PPAAP 715 Query: 122 TRASPLGA---RASPPRSGVSLARPAPGCPRPACEP 154 PL A + P + P P P+ P Sbjct: 716 ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751 Score = 40.4 bits (93), Expect = 0.011 Identities = 60/224 (26%), Positives = 73/224 (32%), Gaps = 54/224 (24%) Query: 41 GGGGAAPGPYP------SAAPPPPGPG--PPPSRQSS--------PPSASDCFGSNGNGG 84 GG PY S P PPGP PPP Q S PP +S S+ Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580 Query: 85 GAFRPGSRRLLGLG--GPPRPF----------VVLLLPLASPGAPPAAPTRASPLGARAS 132 G++ P S G G P PF L +A+ + PA ASP G Sbjct: 581 GSY-PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG---- 635 Query: 133 PPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPA 192 PP G P+PG + A P Y P + + PPA Sbjct: 636 PPPYGKRA--PSPGAYKTATPPGYKP-------------GSPPSFRTGTPPGYRGTSPPA 680 Query: 193 AANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSG 236 KPG SP P P + S + P A SG Sbjct: 681 GPGTFKPG------SPTVGPGPLPPAGPSGLPSLPPPPAAPASG 718 Score = 35.4 bits (80), Expect = 0.36 Identities = 69/267 (25%), Positives = 83/267 (31%), Gaps = 48/267 (17%) Query: 38 SGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS---NGNGGGAFRPGSRRL 94 SG G A P P PP P PP S P ++ + S G P SR Sbjct: 149 SGLSQGPARPYHPPPLFPP--SPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMF 206 Query: 95 LGLGGPPRPFV---------VLLLPLASPGAPPAAPTRASPLGARASPP--------RSG 137 G P P VL P P AA + P G + PP SG Sbjct: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266 Query: 138 VSLARPA------------PGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQ 185 S A P P P PA P P + P + Q Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTP-NLPPPPALRPLNNASASPPGLGAQPL 325 Query: 186 QQQPPPAAANVRKPGG--SGLLASPAAAPSPSSSSVSSSSATAP-----------SSVVA 232 P A + GG G P APSP S +SSSA AP SS A Sbjct: 326 PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA 385 Query: 233 ATSGGGRPGLGRGRNSNKGLPQSTISF 259 ++S +++ LP SF Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSF 412 >gi|48255900 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a [Homo sapiens] Length = 1590 Score = 71.2 bits (173), Expect = 6e-12 Identities = 71/215 (33%), Positives = 89/215 (41%), Gaps = 43/215 (20%) Query: 55 PPPPGPGPPPSRQS-----------SPPSASDCFGSNGNGGGAF---RPGSRRLLGLGGP 100 PP PG GPP S SP A + S +GGG P S+ + G Sbjct: 101 PPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGD 160 Query: 101 PRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLT 160 P+ + + G P +P + L A+ + LAR P P V G T Sbjct: 161 PQA-----MSQPNRGPSPFSPVQLHQLRAQILAYKM---LARGQP-LPETLQLAVQGKRT 211 Query: 161 M---SLKPQQQQQQQQQQQQQQQQQQQQQQQPP---------PAAANVRKPGGSGLLAS- 207 + + QQQQQQQQQQQQQQQQQQQ QQQPP PA N +P G G S Sbjct: 212 LPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSG 271 Query: 208 -------PAAAPSPSSSSVSSSSATAPSSVVAATS 235 P AP S ++A P++ V S Sbjct: 272 PSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPS 306 Score = 36.6 bits (83), Expect = 0.16 Identities = 83/425 (19%), Positives = 153/425 (36%), Gaps = 68/425 (16%) Query: 507 GSG-RQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRV---VNGGVPWPSPCPSPSSR 562 G+G R P MG P S M S + S G+ + V ++GG P+P P S+ Sbjct: 96 GTGMRPPHPGMGPPQS-PMDQHSQGYMSPHPSPLGAPEHVSSPMSGG--GPTPPQMPPSQ 152 Query: 563 PPSRYQSGPNSL--PPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 P + P ++ P R +P P R A G P P + Sbjct: 153 PGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTL 212 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPP--VARTSPSGGTWSSVVS 678 P + + Q+ + + + + P ++ P V PSG Sbjct: 213 PGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPG------ 266 Query: 679 GVPRLSPKTHRPRSPRQNSIGN-TPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASN 737 P LS + + P G +P+ P A P A +P +V P P P+P Sbjct: 267 --PELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAP-GQPSPVLQLQ- 322 Query: 738 RAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDL 797 Q Q + SP + + P E + + ++ +++++L Sbjct: 323 --------------QKQSRISPIQKPQGLDPVE----ILQEREYRLQARIAHRIQELENL 364 Query: 798 K-KFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGS 856 D R + + +++ +LLN R+ L ++ + +D+ +E + Sbjct: 365 PGSLPPDLRTKATVELKAL-RLLNFQRQ------LRQEVVACMRRDTTLETA-------- 409 Query: 857 SKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNP 916 L++ +KR T + + + KQ+K ++E K+ Q +++ Sbjct: 410 ------------LNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQ 457 Query: 917 NAKEF 921 +AK+F Sbjct: 458 HAKDF 462 Score = 35.4 bits (80), Expect = 0.36 Identities = 51/186 (27%), Positives = 62/186 (33%), Gaps = 24/186 (12%) Query: 551 PWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVST 610 P PSP P PS P GP P + P PPS SHP P ST Sbjct: 13 PGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPS-----VSHP----MPTMGST 63 Query: 611 MPKRMSSEGPPRM-SPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPS 669 EG +M P H + GS+ PP PP + Sbjct: 64 ---DFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKG----TGMRPPHPGMGPPQSPMDQH 116 Query: 670 GGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAG-IIPTEAVAMPIPAAS 728 + S P SP P G P+ P + Q G +IP + AM P Sbjct: 117 SQGYMS-----PHPSP-LGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRG 170 Query: 729 PTPASP 734 P+P SP Sbjct: 171 PSPFSP 176 Score = 35.0 bits (79), Expect = 0.47 Identities = 39/148 (26%), Positives = 62/148 (41%), Gaps = 29/148 (19%) Query: 56 PPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPG 115 P P P ++Q P+ + +G PG L GP P LP+ +PG Sbjct: 239 PQQQPPQPQTQQQQQPALVNYNRPSG-------PGPE----LSGPSTP---QKLPVPAPG 284 Query: 116 APPA-APTRASPLGARASPPRSGVSLARPAPGCPRPACE---------PVYGPLTMSLKP 165 P+ AP A+ A A P G S+ +PAPG P P + P+ P L P Sbjct: 285 GRPSPAPPAAAQPPAAAVP---GPSVPQPAPGQPSPVLQLQQKQSRISPIQKP--QGLDP 339 Query: 166 QQQQQQQQQQQQQQQQQQQQQQQPPPAA 193 + Q+++ + Q + + Q+ + P + Sbjct: 340 VEILQEREYRLQARIAHRIQELENLPGS 367 Score = 34.3 bits (77), Expect = 0.81 Identities = 78/355 (21%), Positives = 102/355 (28%), Gaps = 72/355 (20%) Query: 933 TTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAP------NMMYPVPVSPGVQPLYPIPM 986 +TPT P P PS P P+ P +MM P P P V Sbjct: 2 STPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVS------- 54 Query: 987 TPMPVNQAKTYRAVPNMPQQRQDQHHQS----------AMMHPASAAGPPIAATPPAYST 1036 PMP + + PQ+ Q H+ +H S G + P Sbjct: 55 HPMPTMGSTDF------PQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGP 108 Query: 1037 QYVAYSPQQFPNQPLVQHVPHYQSQHP-------HVYSPVIQGNARMMAPPTHAQPGLVS 1089 P P+ QH Y S HP HV SP+ G P +QPG + Sbjct: 109 ----------PQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPP-SQPGALI 157 Query: 1090 SSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTG-------SLAQQYAHPNATLHP 1142 Q + P + Y ++ G LA Q L Sbjct: 158 PGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQ 217 Query: 1143 HTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQ----QQSAIYHAGL 1198 Q QQQ Q P Q Q Q ++ P + S Sbjct: 218 QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQK 277 Query: 1199 APTP-----PSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQ 1248 P P PS P + Q P + P PS QPA P + + Q Sbjct: 278 LPVPAPGGRPSPAPPAAAQPPAAAVPG---------PSVPQPAPGQPSPVLQLQQ 323 Score = 33.9 bits (76), Expect = 1.1 Identities = 77/327 (23%), Positives = 103/327 (31%), Gaps = 56/327 (17%) Query: 929 PKPSTTPTSPRPQAQPSPS--MVGHQQPTPVYTQ-PVCFAPNMMYPVPVSPGVQPLYPIP 985 P P +P S PSP V H PT T P M P+ + I Sbjct: 31 PGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIH 90 Query: 986 MTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM-HPASAAGPPIAATPPAYSTQYVAYSPQ 1044 M + PQ DQH Q M HP+ P ++P + PQ Sbjct: 91 CGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGG---PTPPQ 147 Query: 1045 QFPNQP--LVQHVPHYQSQ---HPHVYSPV--IQGNARMMA----------PPT------ 1081 P+QP L+ P SQ P +SPV Q A+++A P T Sbjct: 148 MPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQ 207 Query: 1082 --HAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNAT 1139 PGL Q +Q + P + P QQ P Sbjct: 208 GKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQ----------TQQQQQPALV 257 Query: 1140 LH--PHTPHPQPSATPTGQQQSQHG-GSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHA 1196 + P P P+ S T Q+ G P+P+P Q AA + PQ Sbjct: 258 NYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQ-------- 309 Query: 1197 GLAPTPPSMTPASNTQSPQNSFPAAQQ 1223 P P +P Q Q+ Q+ Sbjct: 310 ---PAPGQPSPVLQLQQKQSRISPIQK 333 Score = 32.0 bits (71), Expect = 4.0 Identities = 40/169 (23%), Positives = 54/169 (31%), Gaps = 8/169 (4%) Query: 923 PRSFSQPKPSTTPTSPR-PQAQPSPSMVGHQQPTPVYTQ-PVCFAPNMMYPVPVSPGVQP 980 P S P PT P+ P +QP + G Q + P F+P ++ + Sbjct: 131 PEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYK 190 Query: 981 LY----PIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYST 1036 + P+P T Q K R +P + QQ+Q Q Q PP T Sbjct: 191 MLARGQPLPETLQLAVQGK--RTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQT 248 Query: 1037 QYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQP 1085 Q N+P P G APP AQP Sbjct: 249 QQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQP 297 Score = 31.2 bits (69), Expect = 6.8 Identities = 34/176 (19%), Positives = 67/176 (38%), Gaps = 38/176 (21%) Query: 878 PEVTSQGVQ--TSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPS--- 932 PE VQ + P +Q++ +++++ +Q ++ P + P++ Q +P+ Sbjct: 199 PETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVN 258 Query: 933 --------------TTPTS---PRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVS 975 +TP P P +PSP+ QP P P P++ P P Sbjct: 259 YNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQP-PAAAVP---GPSVPQPAPGQ 314 Query: 976 PG-----------VQPLY-PIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHP 1019 P + P+ P + P+ + Q + YR + + Q+ + + P Sbjct: 315 PSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPP 370 >gi|48255898 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform b [Homo sapiens] Length = 1572 Score = 71.2 bits (173), Expect = 6e-12 Identities = 71/215 (33%), Positives = 89/215 (41%), Gaps = 43/215 (20%) Query: 55 PPPPGPGPPPSRQS-----------SPPSASDCFGSNGNGGGAF---RPGSRRLLGLGGP 100 PP PG GPP S SP A + S +GGG P S+ + G Sbjct: 101 PPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGD 160 Query: 101 PRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLT 160 P+ + + G P +P + L A+ + LAR P P V G T Sbjct: 161 PQA-----MSQPNRGPSPFSPVQLHQLRAQILAYKM---LARGQP-LPETLQLAVQGKRT 211 Query: 161 M---SLKPQQQQQQQQQQQQQQQQQQQQQQQPP---------PAAANVRKPGGSGLLAS- 207 + + QQQQQQQQQQQQQQQQQQQ QQQPP PA N +P G G S Sbjct: 212 LPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSG 271 Query: 208 -------PAAAPSPSSSSVSSSSATAPSSVVAATS 235 P AP S ++A P++ V S Sbjct: 272 PSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPS 306 Score = 36.6 bits (83), Expect = 0.16 Identities = 83/425 (19%), Positives = 153/425 (36%), Gaps = 68/425 (16%) Query: 507 GSG-RQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRV---VNGGVPWPSPCPSPSSR 562 G+G R P MG P S M S + S G+ + V ++GG P+P P S+ Sbjct: 96 GTGMRPPHPGMGPPQS-PMDQHSQGYMSPHPSPLGAPEHVSSPMSGG--GPTPPQMPPSQ 152 Query: 563 PPSRYQSGPNSL--PPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 P + P ++ P R +P P R A G P P + Sbjct: 153 PGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTL 212 Query: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPP--VARTSPSGGTWSSVVS 678 P + + Q+ + + + + P ++ P V PSG Sbjct: 213 PGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPG------ 266 Query: 679 GVPRLSPKTHRPRSPRQNSIGN-TPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASN 737 P LS + + P G +P+ P A P A +P +V P P P+P Sbjct: 267 --PELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAP-GQPSPVLQLQ- 322 Query: 738 RAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDL 797 Q Q + SP + + P E + + ++ +++++L Sbjct: 323 --------------QKQSRISPIQKPQGLDPVE----ILQEREYRLQARIAHRIQELENL 364 Query: 798 K-KFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGS 856 D R + + +++ +LLN R+ L ++ + +D+ +E + Sbjct: 365 PGSLPPDLRTKATVELKAL-RLLNFQRQ------LRQEVVACMRRDTTLETA-------- 409 Query: 857 SKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNP 916 L++ +KR T + + + KQ+K ++E K+ Q +++ Sbjct: 410 ------------LNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQ 457 Query: 917 NAKEF 921 +AK+F Sbjct: 458 HAKDF 462 Score = 35.4 bits (80), Expect = 0.36 Identities = 51/186 (27%), Positives = 62/186 (33%), Gaps = 24/186 (12%) Query: 551 PWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVST 610 P PSP P PS P GP P + P PPS SHP P ST Sbjct: 13 PGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPS-----VSHP----MPTMGST 63 Query: 611 MPKRMSSEGPPRM-SPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPS 669 EG +M P H + GS+ PP PP + Sbjct: 64 ---DFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKG----TGMRPPHPGMGPPQSPMDQH 116 Query: 670 GGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAG-IIPTEAVAMPIPAAS 728 + S P SP P G P+ P + Q G +IP + AM P Sbjct: 117 SQGYMS-----PHPSP-LGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRG 170 Query: 729 PTPASP 734 P+P SP Sbjct: 171 PSPFSP 176 Score = 35.0 bits (79), Expect = 0.47 Identities = 39/148 (26%), Positives = 62/148 (41%), Gaps = 29/148 (19%) Query: 56 PPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPG 115 P P P ++Q P+ + +G PG L GP P LP+ +PG Sbjct: 239 PQQQPPQPQTQQQQQPALVNYNRPSG-------PGPE----LSGPSTP---QKLPVPAPG 284 Query: 116 APPA-APTRASPLGARASPPRSGVSLARPAPGCPRPACE---------PVYGPLTMSLKP 165 P+ AP A+ A A P G S+ +PAPG P P + P+ P L P Sbjct: 285 GRPSPAPPAAAQPPAAAVP---GPSVPQPAPGQPSPVLQLQQKQSRISPIQKP--QGLDP 339 Query: 166 QQQQQQQQQQQQQQQQQQQQQQQPPPAA 193 + Q+++ + Q + + Q+ + P + Sbjct: 340 VEILQEREYRLQARIAHRIQELENLPGS 367 Score = 34.3 bits (77), Expect = 0.81 Identities = 78/355 (21%), Positives = 102/355 (28%), Gaps = 72/355 (20%) Query: 933 TTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAP------NMMYPVPVSPGVQPLYPIPM 986 +TPT P P PS P P+ P +MM P P P V Sbjct: 2 STPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVS------- 54 Query: 987 TPMPVNQAKTYRAVPNMPQQRQDQHHQS----------AMMHPASAAGPPIAATPPAYST 1036 PMP + + PQ+ Q H+ +H S G + P Sbjct: 55 HPMPTMGSTDF------PQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGP 108 Query: 1037 QYVAYSPQQFPNQPLVQHVPHYQSQHP-------HVYSPVIQGNARMMAPPTHAQPGLVS 1089 P P+ QH Y S HP HV SP+ G P +QPG + Sbjct: 109 ----------PQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPP-SQPGALI 157 Query: 1090 SSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTG-------SLAQQYAHPNATLHP 1142 Q + P + Y ++ G LA Q L Sbjct: 158 PGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQ 217 Query: 1143 HTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQ----QQSAIYHAGL 1198 Q QQQ Q P Q Q Q ++ P + S Sbjct: 218 QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQK 277 Query: 1199 APTP-----PSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQ 1248 P P PS P + Q P + P PS QPA P + + Q Sbjct: 278 LPVPAPGGRPSPAPPAAAQPPAAAVPG---------PSVPQPAPGQPSPVLQLQQ 323 Score = 33.9 bits (76), Expect = 1.1 Identities = 77/327 (23%), Positives = 103/327 (31%), Gaps = 56/327 (17%) Query: 929 PKPSTTPTSPRPQAQPSPS--MVGHQQPTPVYTQ-PVCFAPNMMYPVPVSPGVQPLYPIP 985 P P +P S PSP V H PT T P M P+ + I Sbjct: 31 PGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIH 90 Query: 986 MTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM-HPASAAGPPIAATPPAYSTQYVAYSPQ 1044 M + PQ DQH Q M HP+ P ++P + PQ Sbjct: 91 CGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGG---PTPPQ 147 Query: 1045 QFPNQP--LVQHVPHYQSQ---HPHVYSPV--IQGNARMMA----------PPT------ 1081 P+QP L+ P SQ P +SPV Q A+++A P T Sbjct: 148 MPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQ 207 Query: 1082 --HAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNAT 1139 PGL Q +Q + P + P QQ P Sbjct: 208 GKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQ----------TQQQQQPALV 257 Query: 1140 LH--PHTPHPQPSATPTGQQQSQHG-GSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHA 1196 + P P P+ S T Q+ G P+P+P Q AA + PQ Sbjct: 258 NYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQ-------- 309 Query: 1197 GLAPTPPSMTPASNTQSPQNSFPAAQQ 1223 P P +P Q Q+ Q+ Sbjct: 310 ---PAPGQPSPVLQLQQKQSRISPIQK 333 Score = 32.0 bits (71), Expect = 4.0 Identities = 40/169 (23%), Positives = 54/169 (31%), Gaps = 8/169 (4%) Query: 923 PRSFSQPKPSTTPTSPR-PQAQPSPSMVGHQQPTPVYTQ-PVCFAPNMMYPVPVSPGVQP 980 P S P PT P+ P +QP + G Q + P F+P ++ + Sbjct: 131 PEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYK 190 Query: 981 LY----PIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYST 1036 + P+P T Q K R +P + QQ+Q Q Q PP T Sbjct: 191 MLARGQPLPETLQLAVQGK--RTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQT 248 Query: 1037 QYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQP 1085 Q N+P P G APP AQP Sbjct: 249 QQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQP 297 Score = 31.2 bits (69), Expect = 6.8 Identities = 34/176 (19%), Positives = 67/176 (38%), Gaps = 38/176 (21%) Query: 878 PEVTSQGVQ--TSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPS--- 932 PE VQ + P +Q++ +++++ +Q ++ P + P++ Q +P+ Sbjct: 199 PETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVN 258 Query: 933 --------------TTPTS---PRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVS 975 +TP P P +PSP+ QP P P P++ P P Sbjct: 259 YNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQP-PAAAVP---GPSVPQPAPGQ 314 Query: 976 PG-----------VQPLY-PIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHP 1019 P + P+ P + P+ + Q + YR + + Q+ + + P Sbjct: 315 PSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPP 370 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 70.5 bits (171), Expect = 1e-11 Identities = 160/702 (22%), Positives = 233/702 (33%), Gaps = 80/702 (11%) Query: 568 QSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAH----GSPAPVSTMPKRMSSEG---- 619 ++G + P A P RPP P PP A G+ V P + G Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 620 -PPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNP-PSEAATPPVARTSPSG------G 671 P +P+A + ++GRG + + S P S R P G Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 Query: 672 TWSSVVSGVPRLSPK-THRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPT 730 +V G +PK + R+++ G TP P A + V +P PA S Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 Query: 731 PASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 P P + SS ++ S + SPA + S++ + +P+ S Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEP----SPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIE---- 846 R PS+ + + + L ++ P KD+ Sbjct: 245 RS--------------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 290 Query: 847 NSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAA 906 +SS T S P SPS PS+ + P SQ + Q + Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATP--PSQATTSLGSPTLQATHSFLPSPPLS 348 Query: 907 EQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAP 966 P A P P++ P S P A PSP V+ F+P Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLS--PLATPSPQA---PNALAVHLLQAPFSP 403 Query: 967 NMMYPV--PVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAG 1024 PV P SP P P+ + P +QA A P P Q S M P SA Sbjct: 404 PPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLAAP--PLQVPPSPPASPPMSP-SATP 458 Query: 1025 PPIAATPPAYSTQYVAYSPQQFP---NQPLVQHVPHYQSQHP--HVYSPVIQGNARMMAP 1079 PP A P A +A P Q P P +Q +P + P +SP +A Sbjct: 459 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518 Query: 1080 PTHAQPGLVSSSATQYGAHEQTHAMYACPKL-----PYNKETSPSFYFAISTGSLAQQYA 1134 P P ++++ Q P+ P + P A++ G Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578 Query: 1135 HPNATLH-PHTPHPQPSATPT-----GQQQSQHGGSHPAPSPVQHHQ--HQAAQALHLAS 1186 P++TL P SAT T G GG+ +P P H AA + A Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638 Query: 1187 PQQQSAIYHAGLAPTPPSMTPAS--------NTQSPQNSFPA 1220 P A L P PP+ P S T+ P+++ PA Sbjct: 639 PLAFRGAPGAPL-PWPPATGPGSADGLCTIYETEGPESATPA 679 Score = 61.6 bits (148), Expect = 5e-09 Identities = 118/493 (23%), Positives = 170/493 (34%), Gaps = 107/493 (21%) Query: 833 KDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPAC 892 + K + K S + + TSG + P +PS + ++ G EV G+ +P+ Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPT-PGTPSPA---MARRSRAAGTEV---GLPRPAPSA 187 Query: 893 KQEKDDKEEKKDAAEQVRKSTLNPN-AKEFNPRS------------FSQPKPSTTPTSPR 939 + + +K + ST P+ A P + S P ++P Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247 Query: 940 PQAQPSPSMVGH-QQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYR 998 P A+ +P H QP P G+Q L P +TP + A Sbjct: 248 PSARGTPRAPAHPSQPKP-------------------KGLQALRPPQVTPPRKDAAPALG 288 Query: 999 AVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQ-HVPH 1057 + + P + S + PP + PP S Q + P P+Q P Sbjct: 289 PLSSSP------------LATPSPSAPPSPSAPP--SLQTLPSPPATPPSQATTSLGSPT 334 Query: 1058 YQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETS 1117 Q+ H + SP + + + PP A P L + A P P + S Sbjct: 335 LQATHSFLPSPPL---SPLATPPPQAPPALALPP------------LQAPPSPPASPPLS 379 Query: 1118 PSFYFAISTGSLAQQYAHPNA-TLH----PHTPHPQPSATPTGQQQSQHGGSHPAPSPVQ 1172 P ++T S PNA +H P +P P P Q S PA PV Sbjct: 380 P-----LATPSPQA----PNALAVHLLQAPFSPPPSPPV--------QAPFSPPASPPVS 422 Query: 1173 HHQHQAAQAL-HLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFP---AAQQTVFTI 1228 +QA LA+P Q + P+PP+ P S + +P P AA Sbjct: 423 PSATPPSQAPPSLAAPPLQ-------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475 Query: 1229 HPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGP---QAALAQSA 1285 P PA PP A G P P+A PM + T PP P A L Q Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535 Query: 1286 LQPIPVSTTAHFP 1298 P P S T P Sbjct: 536 PSP-PASPTLQAP 547 Score = 60.1 bits (144), Expect = 1e-08 Identities = 63/236 (26%), Positives = 83/236 (35%), Gaps = 21/236 (8%) Query: 4 AAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGP- 62 A AP+ A++ +RR + PG S R G P P PSA P PP GP Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197 Query: 63 ----PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASP--GA 116 S S+ + GGG RP SR L PL+SP Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA----------TPLSSPARSG 247 Query: 117 PPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQ 176 P A T +P P+ +L P PR P GPL+ S P Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSPSAPPS 305 Query: 177 QQQQQQQQQQQQPP--PAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSV 230 Q PP P + G L A+ + PSP S +++ AP ++ Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361 Score = 56.2 bits (134), Expect = 2e-07 Identities = 62/208 (29%), Positives = 84/208 (40%), Gaps = 21/208 (10%) Query: 551 PWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVST 610 P SP SPS+ PPS Q+ P+ P P PP+ PP PS P P A P P++ Sbjct: 415 PPASPPVSPSATPPS--QAPPSLAAPPLQVPPSPPASPPMSPSATPP-PQA---PPPLAA 468 Query: 611 MPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF--VSHNPPSEAATPPVARTSP 668 P +++ PP +P A P + + S F + P S ATPP + P Sbjct: 469 PPLQLAK--PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP-PQAPP 525 Query: 669 SGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAM-PIPAA 727 V P SP PR P + SGP L T A+A P P Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL---------TLALAPGPPPPP 576 Query: 728 SPTPASPASNRAVTPSSEAKDSRLQDQR 755 S +P+S S + S + S ++ R Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELR 604 Score = 53.9 bits (128), Expect = 1e-06 Identities = 69/271 (25%), Positives = 98/271 (36%), Gaps = 21/271 (7%) Query: 495 PPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPS 554 PP + R+ +S S ++S P + PS P S S + + P S Sbjct: 191 PPTEGPRKSVS--SASEHSTTEPSPAARRRPSAGGGLQ---RPASRS---LSSSATPLSS 242 Query: 555 PCPS-PSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPK 613 P S PS+R R + P+ P+ RPP P R P+ SP + Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 Query: 614 RMSSEGPPRM----SPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPS 669 S PP + SP A P S G ++ + F+ P S ATPP P Sbjct: 303 PPSPSAPPSLQTLPSPPA-TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-----PQ 356 Query: 670 GGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASP 729 ++ SP P SP P+ + QA P + P+ A Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPPVQAPFS 414 Query: 730 TPASPASNRAVTPSSEAKDSRLQDQRQNSPA 760 PASP + + TP S+A S Q P+ Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445 Score = 53.1 bits (126), Expect = 2e-06 Identities = 76/293 (25%), Positives = 113/293 (38%), Gaps = 58/293 (19%) Query: 495 PPGQRN-----REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGG 549 P GQ+ E ++ G + +P+ +G+ R TS + P+ +R G Sbjct: 119 PLGQKGLRISAEETVARGKATE-APKRSALSAGAR--RDTSGPTPGTPSPAMARRSRAAG 175 Query: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPS--------------RPPSR---- 591 P P+PS+RP + S+ + T PS RP SR Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235 Query: 592 ---PSRPP--SHPSAHGSPA----PVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGS 642 P P S PSA G+P P PK + + PP+++P PR A Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-----PRKDAAPALGPL 290 Query: 643 ISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNT- 701 SS L S + P + PP +T PS P +P + S ++ T Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPS-----------PPATPPSQATTSLGSPTLQATH 339 Query: 702 ---PSGPV--LASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDS 749 PS P+ LA+P P A+ P+ A PASP + TPS +A ++ Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALP-PLQAPPSPPASPPLSPLATPSPQAPNA 391 Score = 52.8 bits (125), Expect = 2e-06 Identities = 70/249 (28%), Positives = 98/249 (39%), Gaps = 56/249 (22%) Query: 7 APRSPAVATES--RRFAAARWPGWRSLQRPARRSGRGGGGAAP------GPYPSAAPPPP 58 +PR P T + R AA G + L A R+G GG P GP ++ PP Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPL---AERAGGIGGATIPESAPRAGPTRTSRPPAS 88 Query: 59 GPG--PPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL--------------GGPPR 102 G G PP++ +SP S S G G RPG GL P R Sbjct: 89 GRGERAPPAKNTSPGPVS----SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144 Query: 103 PFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGC-PRPACEPVYGPLTM 161 + + G P P+ A +RA+ + V L RPAP PRP P GP Sbjct: 145 SALSAGARRDTSGPTPGTPSPAMARRSRAA--GTEVGLPRPAPSARPRP---PTEGP--- 196 Query: 162 SLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAA-APSPSSSSVS 220 ++ + +P PAA R+P G L PA+ + S S++ +S Sbjct: 197 -------------RKSVSSASEHSTTEPSPAAR--RRPSAGGGLQRPASRSLSSSATPLS 241 Query: 221 SSSATAPSS 229 S + + PS+ Sbjct: 242 SPARSGPSA 250 Score = 51.2 bits (121), Expect = 6e-06 Identities = 54/197 (27%), Positives = 71/197 (36%), Gaps = 37/197 (18%) Query: 558 SPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSS 617 SP PP + P + PP + + T P PPS + P P P+P ++ P S+ Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPMSPSA 456 Query: 618 EGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNP--PSEAATPPV-ARTSPSGGTWS 674 PP+ P P L+ P P ATPP+ A SP Sbjct: 457 TPPPQAPPPLAAPP---------------LQLAKPPPQAPPALATPPLQALPSPPAS--- 498 Query: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASP 734 G SP P SP P PVLA+P + P+ P ASPT +P Sbjct: 499 --FPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPS-------PPASPTLQAP 547 Query: 735 ASNRAVTPSSEAKDSRL 751 P + RL Sbjct: 548 RRPPTPGPDTSVSGPRL 564 Score = 50.4 bits (119), Expect = 1e-05 Identities = 106/456 (23%), Positives = 156/456 (34%), Gaps = 58/456 (12%) Query: 855 GSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTL 914 G P + + SP +S+ G T++ + ++ + A E ++S L Sbjct: 91 GERAPPAKNTSPGPVSSPGRASG---TTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147 Query: 915 NPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPV 974 + A+ R S P P T + +++ + + VG +P Sbjct: 148 SAGAR----RDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-------------------- 183 Query: 975 SPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATP--- 1031 +P +P P V+ A + P R+ + PAS + +ATP Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS-SATPLSS 242 Query: 1032 PAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSS 1091 PA S +P+ P P Q+ P +P + A + P + + S S Sbjct: 243 PARSGPSARGTPRA-PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 Query: 1092 ATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAH---PNATLHP-HTPHP 1147 A A + LP T PS S GS Q H P+ L P TP P Sbjct: 302 APP-----SPSAPPSLQTLPSPPATPPS-QATTSLGSPTLQATHSFLPSPPLSPLATPPP 355 Query: 1148 Q--PSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQAL--HLASPQQQSAIYHAGLAP-TP 1202 Q P+ Q + P SP+ QA AL HL AP +P Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415 Query: 1203 PSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTA 1262 P+ P S + +P + P PS P PP P + P P Sbjct: 416 PASPPVSPSATPPSQAP----------PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465 Query: 1263 HAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFP 1298 A L +PP ALA LQ +P S A FP Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALP-SPPASFP 500 Score = 47.4 bits (111), Expect = 9e-05 Identities = 63/215 (29%), Positives = 82/215 (38%), Gaps = 42/215 (19%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP-----------SRPSRPP--SHP 599 PS P + PP + P + PP + + T PP PP P PP + P Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487 Query: 600 SAHGSPAPVSTMPKR--MSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSE 657 P+P ++ P + S MSP A P+ V A + PPS Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP---------LLQVPPSP 538 Query: 658 AATPPV--ARTSPSGGTWSSVVSGVPRLS-PKTHRPRSPRQNSIGNTPSGPVLA--SPQA 712 A+P + R P+ G +S VSG PRL+ P P S +T SGP LA S A Sbjct: 539 PASPTLQAPRRPPTPGPDTS-VSG-PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 596 Query: 713 GIIPTE-----------AVAMPIPAASPTPASPAS 736 P E A A P P A PA+ Sbjct: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 631 Score = 47.0 bits (110), Expect = 1e-04 Identities = 60/209 (28%), Positives = 79/209 (37%), Gaps = 29/209 (13%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP-APVSTM 611 PSP SP + PP + PP A P P PPS P+ PP P A SP AP + Sbjct: 343 PSPPLSPLATPPPQ-------APPALALP--PLQAPPSPPASPPLSPLATPSPQAPNALA 393 Query: 612 PKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATP-PVARTSPSG 670 + + P SP Q P + S +S S PPS AA P V + P+ Sbjct: 394 VHLLQAPFSPPPSPPVQA-PFSPPASP---PVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 Query: 671 GTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPT 730 S + P+ P P P Q + + P LA+P P+ A Sbjct: 450 PPMSPSATPPPQAPPPLAAP--PLQLAKPPPQAPPALATP------------PLQALPSP 495 Query: 731 PASPASNRAVTPSSEAKDSRLQDQRQNSP 759 PAS +PS+ S L +P Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQAP 524 Score = 45.8 bits (107), Expect = 3e-04 Identities = 68/265 (25%), Positives = 98/265 (36%), Gaps = 78/265 (29%) Query: 553 PSPCPSPSSRPPSRYQS-----------GPNSLPPRAATPTRP----------------- 584 P P+ +SRPP+ + GP S P RA+ TRP Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134 Query: 585 ---PSRPPSRPS------RPPSHPSAHGSPAPVSTMPKRMSSE--GPPRMSPKAQRHPRN 633 + P R + R S P+ G+P+P R + G PR +P A+ P Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGLPRPAPSARPRP-- 191 Query: 634 HRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGG-------TWSSVVSGVPRLSPK 686 R S+SS E + P P AR PS G + S S P SP Sbjct: 192 -PTEGPRKSVSSASEHSTTEP------SPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244 Query: 687 THRPR---SPRQNSIGNTPSGPVL--------------ASPQAGIIPTEAVAMPIPAASP 729 P +PR + + P L A+P G + + +A P P+A P Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304 Query: 730 TPASPASNRAV-----TPSSEAKDS 749 +P++P S + + TP S+A S Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTS 329 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/198 (26%), Positives = 69/198 (34%), Gaps = 37/198 (18%) Query: 46 APGPYPSAAPPPPGPGP--------PPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL 97 +P P A PPP P PPS +SPP + L Sbjct: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP--------------------LAT 383 Query: 98 GGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYG 157 P P + + L +P +PP +P +P ASPP S S P+ P A P+ Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQV 442 Query: 158 PLTMSLKPQQQQQQQQQQQQQ---QQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAP-- 212 P + P Q Q + PP A + P L + PA+ P Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502 Query: 213 ---SPSSSSVSSSSATAP 227 SPS+S S AT P Sbjct: 503 APFSPSASLPMSPLATPP 520 Score = 45.8 bits (107), Expect = 3e-04 Identities = 59/228 (25%), Positives = 79/228 (34%), Gaps = 40/228 (17%) Query: 54 APPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLAS 113 AP P P PP SPP++ S P S+ L PP L +P + Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSA-------TPPSQAPPSLAAPP-----LQVPPSP 446 Query: 114 PGAPPAAPTRASPLGARASPPRSG--VSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQ 171 P +PP +P+ P +A PP + + LA+P P P P PL P Sbjct: 447 PASPPMSPSATPP--PQAPPPLAAPPLQLAKPPPQAPPALATP---PLQALPSPPASFPG 501 Query: 172 QQQQQQQQQQQQQQQQQPPPAAANV---------RKPGGSGLLASPAAAPSPS-SSSVSS 221 Q PPP A V P S L +P P+P +SVS Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561 Query: 222 SSAT---------APSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFD 260 T PS ++T G P L +S P+ +D Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSSATSTPEELRGYD 607 Score = 45.1 bits (105), Expect = 5e-04 Identities = 56/210 (26%), Positives = 75/210 (35%), Gaps = 24/210 (11%) Query: 45 AAPGPYPSAAPPPPGP----GPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGP 100 A+P PSA PP P PP SPP++ S A P + L L P Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 Query: 101 P--RPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGP 158 P P + PL + +PPA+ +P AS P S LA P P P PV Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS--PLATPPPQAP-----PVLAA 529 Query: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSS 218 + + P Q ++ PP G L + A P P S Sbjct: 530 PLLQVPPSPPASPTLQAPRR-----------PPTPGPDTSVSGPRLTLALAPGPPPPPSR 578 Query: 219 VSSSSATAPSSVVAATSGGGRPGLGRGRNS 248 SS+ + P ++S P RG +S Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDS 608 Score = 37.0 bits (84), Expect = 0.12 Identities = 49/174 (28%), Positives = 57/174 (32%), Gaps = 24/174 (13%) Query: 4 AAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPP 63 A P++P V P +LQ P R G + GP + A PGP PP Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA-LAPGPPPP 575 Query: 64 PSRQ-----------------SSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVV 106 PSR +S P + S GG A P L P Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635 Query: 107 LLLPLA---SPGAP---PAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEP 154 PLA +PGAP P A S G G A PAPG P P Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689 Score = 36.2 bits (82), Expect = 0.21 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 11/162 (6%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSP-APVSTM 611 P P P P SR PS SGP+ L +++ T P S P +A P A ++ Sbjct: 570 PGP-PPPPSRSPSSTLSGPD-LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627 Query: 612 PKRMSSEGP--PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSP- 668 S GP P A P + G GS + GL + E+ATP P Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS-ADGLCTIYETEGPESATPAPGALDPG 686 Query: 669 -SGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLAS 709 S GT + + RSP+Q +G P G + AS Sbjct: 687 PSPGTSGGKAAAGAGAGASS---RSPKQARLGELPLGALQAS 725 Score = 35.8 bits (81), Expect = 0.28 Identities = 60/230 (26%), Positives = 81/230 (35%), Gaps = 52/230 (22%) Query: 38 SGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGL 97 + R G P P S PPPP P+A G+ G G +P + R G+ Sbjct: 18 AARAPGLLTPRPPGSPRPPPP----------VTPAALRVLGAAGAVGR--KPLAERAGGI 65 Query: 98 GGPPRPFVVLLLPLASPGAPPAAPTR-----ASPLGARASPPRS----GVSLARPAPGCP 148 GG P AP A PTR AS G RA P ++ VS A G Sbjct: 66 GGATIP----------ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115 Query: 149 RPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQ--------PPPAAA------ 194 RP G L +S + + + + ++ ++ P PA A Sbjct: 116 RPGPLGQKG-LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174 Query: 195 ----NVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVV--AATSGGG 238 + +P S P P S SS S S T PS ++GGG Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224 >gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] Length = 1220 Score = 70.5 bits (171), Expect = 1e-11 Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 44/307 (14%) Query: 1022 AAGPPIAATPPAYSTQYVAYSPQQFPNQ---PLVQH--VPHYQSQ--HPHVYSPVIQGNA 1074 A G P+A + + + Y QQ P P+ H +P Q+Q +PH +P Sbjct: 789 AQGEPVAG----HESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENP------ 838 Query: 1075 RMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLA---- 1130 PP G V+ +A H P P + P+ + TG A Sbjct: 839 ---PPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRP 895 Query: 1131 -QQYAHPNATLHPHTPHPQPSATPTGQQQ---SQHGGSHPAPSPVQHHQHQAAQALHLAS 1186 Q A P + +P+TP+ +++ TGQ Q +QH S P SP A Sbjct: 896 QQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSP----------ATSFPP 945 Query: 1187 PQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHV 1246 P A + G PPS + + + PAA + + + Q + +PP + V Sbjct: 946 PPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPAS-QRTGPQNGWNDPPALNRV 1004 Query: 1247 PQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQA-ALAQSALQPIPVSTTAHFPYMTHPSV 1305 P + +P + P+ P G PQ+ L Q P+P+S+ + FP P Sbjct: 1005 P----KKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGG 1060 Query: 1306 QAHHQQQ 1312 Q H Q Sbjct: 1061 QPFHGVQ 1067 Score = 34.3 bits (77), Expect = 0.81 Identities = 43/208 (20%), Positives = 65/208 (31%), Gaps = 11/208 (5%) Query: 557 PSPSSRPPSRYQSGPNSLPPRAAT-PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 P + PP + N P A PT P P P P P P T M Sbjct: 833 PHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAM 892 Query: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 P P + +P +S+ + + + S + P P + +S Sbjct: 893 YRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGAS 952 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL-----ASPQAGIIPTEAV-AMPIPAASP 729 G P P + P + G P+ L PQ G A+ +P P Sbjct: 953 FQHGGPGAPPSSSAYALP-PGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMP 1011 Query: 730 ---TPASPASNRAVTPSSEAKDSRLQDQ 754 P P ++ + P + + LQ Q Sbjct: 1012 ENFMPPVPITSPIMNPLGDPQSQMLQQQ 1039 Score = 32.7 bits (73), Expect = 2.3 Identities = 46/200 (23%), Positives = 65/200 (32%), Gaps = 33/200 (16%) Query: 46 APGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGG--PPRP 103 +PG + PP P P P Q P FG+ G+ +RP P P Sbjct: 860 SPGHMHTQVPPYPQPQPYQPAQPYP------FGTGGSA--MYRPQQPVAPPTSNAYPNTP 911 Query: 104 FVVLLLPLASPGAPPAAPTRAS-----PLGARASPPRSGVSLARPAPGCPRPACEPVYGP 158 ++ AA +AS P + PP SG S PG P + P Sbjct: 912 YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPP 971 Query: 159 LTMSLKPQQQQQQQQQQQQQQ---------------QQQQQQQQQPPPAAANVRKPGG-- 201 T P + Q+ Q ++ + P P + + P G Sbjct: 972 GTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDP 1031 Query: 202 -SGLLASPAAAPSPSSSSVS 220 S +L +AP P SS S Sbjct: 1032 QSQMLQQQPSAPVPLSSQSS 1051 >gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] Length = 1181 Score = 70.5 bits (171), Expect = 1e-11 Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 44/307 (14%) Query: 1022 AAGPPIAATPPAYSTQYVAYSPQQFPNQ---PLVQH--VPHYQSQ--HPHVYSPVIQGNA 1074 A G P+A + + + Y QQ P P+ H +P Q+Q +PH +P Sbjct: 750 AQGEPVAG----HESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENP------ 799 Query: 1075 RMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLA---- 1130 PP G V+ +A H P P + P+ + TG A Sbjct: 800 ---PPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRP 856 Query: 1131 -QQYAHPNATLHPHTPHPQPSATPTGQQQ---SQHGGSHPAPSPVQHHQHQAAQALHLAS 1186 Q A P + +P+TP+ +++ TGQ Q +QH S P SP A Sbjct: 857 QQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSP----------ATSFPP 906 Query: 1187 PQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHV 1246 P A + G PPS + + + PAA + + + Q + +PP + V Sbjct: 907 PPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPAS-QRTGPQNGWNDPPALNRV 965 Query: 1247 PQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQA-ALAQSALQPIPVSTTAHFPYMTHPSV 1305 P + +P + P+ P G PQ+ L Q P+P+S+ + FP P Sbjct: 966 P----KKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGG 1021 Query: 1306 QAHHQQQ 1312 Q H Q Sbjct: 1022 QPFHGVQ 1028 Score = 34.3 bits (77), Expect = 0.81 Identities = 43/208 (20%), Positives = 65/208 (31%), Gaps = 11/208 (5%) Query: 557 PSPSSRPPSRYQSGPNSLPPRAAT-PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 P + PP + N P A PT P P P P P P T M Sbjct: 794 PHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAM 853 Query: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 P P + +P +S+ + + + S + P P + +S Sbjct: 854 YRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGAS 913 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL-----ASPQAGIIPTEAV-AMPIPAASP 729 G P P + P + G P+ L PQ G A+ +P P Sbjct: 914 FQHGGPGAPPSSSAYALP-PGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMP 972 Query: 730 ---TPASPASNRAVTPSSEAKDSRLQDQ 754 P P ++ + P + + LQ Q Sbjct: 973 ENFMPPVPITSPIMNPLGDPQSQMLQQQ 1000 Score = 32.7 bits (73), Expect = 2.3 Identities = 46/200 (23%), Positives = 65/200 (32%), Gaps = 33/200 (16%) Query: 46 APGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGG--PPRP 103 +PG + PP P P P Q P FG+ G+ +RP P P Sbjct: 821 SPGHMHTQVPPYPQPQPYQPAQPYP------FGTGGSA--MYRPQQPVAPPTSNAYPNTP 872 Query: 104 FVVLLLPLASPGAPPAAPTRAS-----PLGARASPPRSGVSLARPAPGCPRPACEPVYGP 158 ++ AA +AS P + PP SG S PG P + P Sbjct: 873 YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPP 932 Query: 159 LTMSLKPQQQQQQQQQQQQQQ---------------QQQQQQQQQPPPAAANVRKPGG-- 201 T P + Q+ Q ++ + P P + + P G Sbjct: 933 GTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDP 992 Query: 202 -SGLLASPAAAPSPSSSSVS 220 S +L +AP P SS S Sbjct: 993 QSQMLQQQPSAPVPLSSQSS 1012 >gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] Length = 1220 Score = 70.5 bits (171), Expect = 1e-11 Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 44/307 (14%) Query: 1022 AAGPPIAATPPAYSTQYVAYSPQQFPNQ---PLVQH--VPHYQSQ--HPHVYSPVIQGNA 1074 A G P+A + + + Y QQ P P+ H +P Q+Q +PH +P Sbjct: 789 AQGEPVAG----HESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENP------ 838 Query: 1075 RMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLA---- 1130 PP G V+ +A H P P + P+ + TG A Sbjct: 839 ---PPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRP 895 Query: 1131 -QQYAHPNATLHPHTPHPQPSATPTGQQQ---SQHGGSHPAPSPVQHHQHQAAQALHLAS 1186 Q A P + +P+TP+ +++ TGQ Q +QH S P SP A Sbjct: 896 QQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSP----------ATSFPP 945 Query: 1187 PQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHV 1246 P A + G PPS + + + PAA + + + Q + +PP + V Sbjct: 946 PPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPAS-QRTGPQNGWNDPPALNRV 1004 Query: 1247 PQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQA-ALAQSALQPIPVSTTAHFPYMTHPSV 1305 P + +P + P+ P G PQ+ L Q P+P+S+ + FP P Sbjct: 1005 P----KKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGG 1060 Query: 1306 QAHHQQQ 1312 Q H Q Sbjct: 1061 QPFHGVQ 1067 Score = 34.3 bits (77), Expect = 0.81 Identities = 43/208 (20%), Positives = 65/208 (31%), Gaps = 11/208 (5%) Query: 557 PSPSSRPPSRYQSGPNSLPPRAAT-PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 P + PP + N P A PT P P P P P P T M Sbjct: 833 PHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAM 892 Query: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 P P + +P +S+ + + + S + P P + +S Sbjct: 893 YRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGAS 952 Query: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL-----ASPQAGIIPTEAV-AMPIPAASP 729 G P P + P + G P+ L PQ G A+ +P P Sbjct: 953 FQHGGPGAPPSSSAYALP-PGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMP 1011 Query: 730 ---TPASPASNRAVTPSSEAKDSRLQDQ 754 P P ++ + P + + LQ Q Sbjct: 1012 ENFMPPVPITSPIMNPLGDPQSQMLQQQ 1039 Score = 32.7 bits (73), Expect = 2.3 Identities = 46/200 (23%), Positives = 65/200 (32%), Gaps = 33/200 (16%) Query: 46 APGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGG--PPRP 103 +PG + PP P P P Q P FG+ G+ +RP P P Sbjct: 860 SPGHMHTQVPPYPQPQPYQPAQPYP------FGTGGSA--MYRPQQPVAPPTSNAYPNTP 911 Query: 104 FVVLLLPLASPGAPPAAPTRAS-----PLGARASPPRSGVSLARPAPGCPRPACEPVYGP 158 ++ AA +AS P + PP SG S PG P + P Sbjct: 912 YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPP 971 Query: 159 LTMSLKPQQQQQQQQQQQQQQ---------------QQQQQQQQQPPPAAANVRKPGG-- 201 T P + Q+ Q ++ + P P + + P G Sbjct: 972 GTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDP 1031 Query: 202 -SGLLASPAAAPSPSSSSVS 220 S +L +AP P SS S Sbjct: 1032 QSQMLQQQPSAPVPLSSQSS 1051 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 68.2 bits (165), Expect = 5e-11 Identities = 84/412 (20%), Positives = 158/412 (38%), Gaps = 49/412 (11%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP---------SHPSAHG 603 P+P P + ++ P + P+ PT P+ P +P P++ Sbjct: 554 PAPTTPKEPAPTTPKETAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611 Query: 604 SPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPV 663 P T PK + P +P + P + +G+ + L+ + P + A + Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKEL 668 Query: 664 ARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMP 723 A T+ G T ++ P +PK P +P++ + TP P +P+ T V+ P Sbjct: 669 APTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTP 726 Query: 724 IPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGI 783 PT + + + TP A+ + +NSP KE P +P+ +K Sbjct: 727 TTTKEPTTIHKSPDES-TPELSAEPT--PKALENSP---KEPGVPTTKTPAATK------ 774 Query: 784 SPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDS 843 P ++ K K + D R P +T+ + EK+ + S Sbjct: 775 -PEMTTTAKD----KTTERDLRTTPETTTAAPKMTKETATTTEKTTE------------S 817 Query: 844 FIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKK 903 I +++ TS +++ +P ++ + T P+VT+ ++ + ++ + K Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTT---LAPKVTTTKKTITTTEIMNKPEETAKPK 874 Query: 904 DAAEQVRKSTLNPNAKEFNPRS-FSQPKPSTTPTSPRPQAQPSPSMVGHQQP 954 D A + +T P P+ S KP T P +P+ P+P + P Sbjct: 875 DRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 926 Score = 60.5 bits (145), Expect = 1e-08 Identities = 116/620 (18%), Positives = 210/620 (33%), Gaps = 67/620 (10%) Query: 449 ESSAQYKARVALENDDRSEEEKYTAV---QRNSSEREGHSINTRENKYIPPGQR------ 499 E+S +E + + K T+ ++ +S +E SI K + P + Sbjct: 139 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 198 Query: 500 -NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPS 558 E + G +P+ P + P+ +T P + + + P P+ Sbjct: 199 PKAETTTKGPAL-TTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPT 250 Query: 559 PS-SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPA-PVSTMPKRMS 616 + S P + + P + A T + P+ ++ P + SA +P P T PK+ + Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310 Query: 617 SEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPP--VARTSPSGGTWS 674 P +P + P + + + E P A T P A T+P + Sbjct: 311 PTTPKEPAPTTPKEP---TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367 Query: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASP 734 + P + K P +P++ + T S P A PT + P P+P + Sbjct: 368 TPKEPAP-TTTKEPSPTTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTT 423 Query: 735 ASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEHRK 792 TP A + ++ +P KE P E +P+ +K +P Sbjct: 424 KEPAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTKKP----APTTP---- 471 Query: 793 QIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNC 852 K P T+ + + L EK +K P+ + + Sbjct: 472 --------KEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEP 522 Query: 853 TSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTS----SPACKQEKDDKEEKKDAAEQ 908 T + + +P+ + NT + P + T+ +P +E K A Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582 Query: 909 VRK----STLNPNAKEFNPRSFSQPKPST----TPTSPRPQAQPSPSMVGHQQP-TPVYT 959 +++ + P KE P + +P +T PT+P+ A +P P P T Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642 Query: 960 QPVCFAP-NMMYPVPVSP-GVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM 1017 P AP + P P +P P P T + + P P++ + Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702 Query: 1018 HPASAAGPPIAATPPAYSTQ 1037 P TPP +++ Sbjct: 703 TTPKKPAPTTPETPPPTTSE 722 Score = 58.9 bits (141), Expect = 3e-08 Identities = 91/442 (20%), Positives = 143/442 (32%), Gaps = 55/442 (12%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMP 612 PSP +P P+ +S P + A T T+ P PS P+ PAP T P Sbjct: 380 PSPT-TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-----PTTTKEPAP--TTP 431 Query: 613 KRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGT 672 K + P + +P + P + P+ T A T+P Sbjct: 432 KEPAPTTPKKPAPTTPKEPAP----------------TTPKEPAPTTTKKPAPTTPKEPA 475 Query: 673 WSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPA 732 ++ P +PK P +P + TP P +P+ T P P P Sbjct: 476 PTTPKETAP-TTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533 Query: 733 SPASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEH 790 +P + TP A + ++ +P KE P ET+P+ KG +P + Sbjct: 534 TPKAAAPNTPKEPAPTT----PKEPAPTTPKEPAPTTPKETAPT----TPKGTAPTTLKE 585 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K + L P++T E DK P+ + Sbjct: 586 PAPTTPKKPAPKE--LAPTTTKEPTSTTC--------------DKPAPTTPKGTAPTTPK 629 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 + K +P+ T + P + + A Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689 Query: 911 KSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM-M 969 K T KE P + +P P TTP +P P + ++PT ++ P P + Sbjct: 690 KETAPTTPKEPAPTTPKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748 Query: 970 YPVPVSPGVQPLYP-IPMTPMP 990 P P + P P +P T P Sbjct: 749 EPTPKALENSPKEPGVPTTKTP 770 Score = 57.0 bits (136), Expect = 1e-07 Identities = 122/597 (20%), Positives = 194/597 (32%), Gaps = 74/597 (12%) Query: 759 PAGNKENIKPN-ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQ 817 P + ++ PN +TS S NK E ++ K+ D + + +S E+ Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNK---ETTVETKETTTTNKQTSTDGKEKTTSAKET--- 176 Query: 818 LLNKNREGEKSRDLI---KDKIEPSAKDSFIENSSSNCTSGSSKPNSP----SISPSILS 870 ++ E ++DL K +P+ K + T P +P S +P + Sbjct: 177 ---QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233 Query: 871 NTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPK 930 T K P + PA K K+ A K KE P + +P Sbjct: 234 PTTIKSAPTTPKE------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 287 Query: 931 PSTTPTSPRPQAQPSPSMVGHQQPT------------PVYTQPVCFAPNMMYPVPVSPGV 978 P+TT ++P +P+P+ PT P T P AP P P +P Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-K 346 Query: 979 QPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMH---PASAAGPPIAATPPAYS 1035 +P P P P + P P + P + P PA + Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406 Query: 1036 TQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVS---SSA 1092 T A + + P+ + + P +P + AP T +P + + Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAP 460 Query: 1093 TQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSAT 1152 T T P P KET+P+ + T + ++ A P P P+ A Sbjct: 461 TTTKKPAPTTPKEPAPTTP--KETAPTTPKKL-TPTTPEKLA-PTTPEKPAPTTPEELAP 516 Query: 1153 PTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQ 1212 T ++ + PAP+ + + +P++ + APT P T + + Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576 Query: 1213 -------------SPQNSFPAAQQTVFTIHPSHV---QPAYTNP----PHMAHVPQAHVQ 1252 +P+ P T P+ +PA T P P P Sbjct: 577 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 636 Query: 1253 SGMVPSHPTAHAPMMLMTTQP--PGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307 P+ P AP L P P P P STT+ P T P A Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 693 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 68.2 bits (165), Expect = 5e-11 Identities = 84/412 (20%), Positives = 158/412 (38%), Gaps = 49/412 (11%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP---------SHPSAHG 603 P+P P + ++ P + P+ PT P+ P +P P++ Sbjct: 595 PAPTTPKEPAPTTPKETAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652 Query: 604 SPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPV 663 P T PK + P +P + P + +G+ + L+ + P + A + Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKEL 709 Query: 664 ARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMP 723 A T+ G T ++ P +PK P +P++ + TP P +P+ T V+ P Sbjct: 710 APTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTP 767 Query: 724 IPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGI 783 PT + + + TP A+ + +NSP KE P +P+ +K Sbjct: 768 TTTKEPTTIHKSPDES-TPELSAEPT--PKALENSP---KEPGVPTTKTPAATK------ 815 Query: 784 SPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDS 843 P ++ K K + D R P +T+ + EK+ + S Sbjct: 816 -PEMTTTAKD----KTTERDLRTTPETTTAAPKMTKETATTTEKTTE------------S 858 Query: 844 FIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKK 903 I +++ TS +++ +P ++ + T P+VT+ ++ + ++ + K Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTT---LAPKVTTTKKTITTTEIMNKPEETAKPK 915 Query: 904 DAAEQVRKSTLNPNAKEFNPRS-FSQPKPSTTPTSPRPQAQPSPSMVGHQQP 954 D A + +T P P+ S KP T P +P+ P+P + P Sbjct: 916 DRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 967 Score = 60.5 bits (145), Expect = 1e-08 Identities = 116/620 (18%), Positives = 210/620 (33%), Gaps = 67/620 (10%) Query: 449 ESSAQYKARVALENDDRSEEEKYTAV---QRNSSEREGHSINTRENKYIPPGQR------ 499 E+S +E + + K T+ ++ +S +E SI K + P + Sbjct: 180 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 239 Query: 500 -NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPS 558 E + G +P+ P + P+ +T P + + + P P+ Sbjct: 240 PKAETTTKGPAL-TTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPT 291 Query: 559 PS-SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPA-PVSTMPKRMS 616 + S P + + P + A T + P+ ++ P + SA +P P T PK+ + Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351 Query: 617 SEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPP--VARTSPSGGTWS 674 P +P + P + + + E P A T P A T+P + Sbjct: 352 PTTPKEPAPTTPKEP---TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408 Query: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASP 734 + P + K P +P++ + T S P A PT + P P+P + Sbjct: 409 TPKEPAP-TTTKEPSPTTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTT 464 Query: 735 ASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEHRK 792 TP A + ++ +P KE P E +P+ +K +P Sbjct: 465 KEPAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTKKP----APTTP---- 512 Query: 793 QIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNC 852 K P T+ + + L EK +K P+ + + Sbjct: 513 --------KEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEP 563 Query: 853 TSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTS----SPACKQEKDDKEEKKDAAEQ 908 T + + +P+ + NT + P + T+ +P +E K A Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623 Query: 909 VRK----STLNPNAKEFNPRSFSQPKPST----TPTSPRPQAQPSPSMVGHQQP-TPVYT 959 +++ + P KE P + +P +T PT+P+ A +P P P T Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683 Query: 960 QPVCFAP-NMMYPVPVSP-GVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM 1017 P AP + P P +P P P T + + P P++ + Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743 Query: 1018 HPASAAGPPIAATPPAYSTQ 1037 P TPP +++ Sbjct: 744 TTPKKPAPTTPETPPPTTSE 763 Score = 58.9 bits (141), Expect = 3e-08 Identities = 91/442 (20%), Positives = 143/442 (32%), Gaps = 55/442 (12%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMP 612 PSP +P P+ +S P + A T T+ P PS P+ PAP T P Sbjct: 421 PSPT-TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-----PTTTKEPAP--TTP 472 Query: 613 KRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGT 672 K + P + +P + P + P+ T A T+P Sbjct: 473 KEPAPTTPKKPAPTTPKEPAP----------------TTPKEPAPTTTKKPAPTTPKEPA 516 Query: 673 WSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPA 732 ++ P +PK P +P + TP P +P+ T P P P Sbjct: 517 PTTPKETAP-TTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574 Query: 733 SPASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEH 790 +P + TP A + ++ +P KE P ET+P+ KG +P + Sbjct: 575 TPKAAAPNTPKEPAPTT----PKEPAPTTPKEPAPTTPKETAPT----TPKGTAPTTLKE 626 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K + L P++T E DK P+ + Sbjct: 627 PAPTTPKKPAPKE--LAPTTTKEPTSTTC--------------DKPAPTTPKGTAPTTPK 670 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 + K +P+ T + P + + A Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730 Query: 911 KSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM-M 969 K T KE P + +P P TTP +P P + ++PT ++ P P + Sbjct: 731 KETAPTTPKEPAPTTPKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789 Query: 970 YPVPVSPGVQPLYP-IPMTPMP 990 P P + P P +P T P Sbjct: 790 EPTPKALENSPKEPGVPTTKTP 811 Score = 57.0 bits (136), Expect = 1e-07 Identities = 122/597 (20%), Positives = 194/597 (32%), Gaps = 74/597 (12%) Query: 759 PAGNKENIKPN-ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQ 817 P + ++ PN +TS S NK E ++ K+ D + + +S E+ Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNK---ETTVETKETTTTNKQTSTDGKEKTTSAKET--- 217 Query: 818 LLNKNREGEKSRDLI---KDKIEPSAKDSFIENSSSNCTSGSSKPNSP----SISPSILS 870 ++ E ++DL K +P+ K + T P +P S +P + Sbjct: 218 ---QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274 Query: 871 NTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPK 930 T K P + PA K K+ A K KE P + +P Sbjct: 275 PTTIKSAPTTPKE------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 328 Query: 931 PSTTPTSPRPQAQPSPSMVGHQQPT------------PVYTQPVCFAPNMMYPVPVSPGV 978 P+TT ++P +P+P+ PT P T P AP P P +P Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-K 387 Query: 979 QPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMH---PASAAGPPIAATPPAYS 1035 +P P P P + P P + P + P PA + Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447 Query: 1036 TQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVS---SSA 1092 T A + + P+ + + P +P + AP T +P + + Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAP 501 Query: 1093 TQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSAT 1152 T T P P KET+P+ + T + ++ A P P P+ A Sbjct: 502 TTTKKPAPTTPKEPAPTTP--KETAPTTPKKL-TPTTPEKLA-PTTPEKPAPTTPEELAP 557 Query: 1153 PTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQ 1212 T ++ + PAP+ + + +P++ + APT P T + + Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617 Query: 1213 -------------SPQNSFPAAQQTVFTIHPSHV---QPAYTNP----PHMAHVPQAHVQ 1252 +P+ P T P+ +PA T P P P Sbjct: 618 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 677 Query: 1253 SGMVPSHPTAHAPMMLMTTQP--PGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307 P+ P AP L P P P P STT+ P T P A Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 734 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 68.2 bits (165), Expect = 5e-11 Identities = 84/412 (20%), Positives = 158/412 (38%), Gaps = 49/412 (11%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP---------SHPSAHG 603 P+P P + ++ P + P+ PT P+ P +P P++ Sbjct: 647 PAPTTPKEPAPTTPKETAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704 Query: 604 SPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPV 663 P T PK + P +P + P + +G+ + L+ + P + A + Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKEL 761 Query: 664 ARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMP 723 A T+ G T ++ P +PK P +P++ + TP P +P+ T V+ P Sbjct: 762 APTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTP 819 Query: 724 IPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGI 783 PT + + + TP A+ + +NSP KE P +P+ +K Sbjct: 820 TTTKEPTTIHKSPDES-TPELSAEPT--PKALENSP---KEPGVPTTKTPAATK------ 867 Query: 784 SPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDS 843 P ++ K K + D R P +T+ + EK+ + S Sbjct: 868 -PEMTTTAKD----KTTERDLRTTPETTTAAPKMTKETATTTEKTTE------------S 910 Query: 844 FIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKK 903 I +++ TS +++ +P ++ + T P+VT+ ++ + ++ + K Sbjct: 911 KITATTTQVTSTTTQDTTPFKITTLKTTT---LAPKVTTTKKTITTTEIMNKPEETAKPK 967 Query: 904 DAAEQVRKSTLNPNAKEFNPRS-FSQPKPSTTPTSPRPQAQPSPSMVGHQQP 954 D A + +T P P+ S KP T P +P+ P+P + P Sbjct: 968 DRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1019 Score = 62.0 bits (149), Expect = 4e-09 Identities = 157/773 (20%), Positives = 256/773 (33%), Gaps = 105/773 (13%) Query: 585 PSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSIS 644 P+ PPS PP PS G+ + + KR SPK + +V Sbjct: 69 PTSPPSSKKAPP--PS--GASQTIKSTTKR---------SPKPPNKKKTKKVIESEEITE 115 Query: 645 SGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGN--TP 702 VS N S +++ + +S SS S R K + + ++N TP Sbjct: 116 E--HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 173 Query: 703 SGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGN 762 PV+ +G+ + +P ++ N+ V+ S + ++ P Sbjct: 174 KPPVVDEAGSGLDNGD-----FKVTTPDTSTTQHNK-VSTSPKITTAK--------PINP 219 Query: 763 KENIKPN-ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNK 821 + ++ PN +TS S NK E ++ K+ D + + +S E+ + Sbjct: 220 RPSLPPNSDTSKETSLTVNK---ETTVETKETTTTNKQTSTDGKEKTTSAKET------Q 270 Query: 822 NREGEKSRDLI---KDKIEPSAKDSFIENSSSNCTSGSSKPNSP----SISPSILSNTEH 874 + E ++DL K +P+ K + T P +P S +P + T Sbjct: 271 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 330 Query: 875 KRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTT 934 K P + PA K K+ A K KE P + +P P+TT Sbjct: 331 KSAPTTPKE------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384 Query: 935 PTSPRPQAQPSPSMVGHQQPT------------PVYTQPVCFAPNMMYPVPVSPGVQPLY 982 ++P +P+P+ PT P T P AP P P +P +P Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-KEPAP 443 Query: 983 PIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMH---PASAAGPPIAATPPAYSTQYV 1039 P P P + P P + P + P PA +T Sbjct: 444 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 503 Query: 1040 AYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVS---SSATQYG 1096 A + + P+ + + P +P + AP T +P + + T Sbjct: 504 APTTPKEPSPTTTKEPAPTTPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTK 557 Query: 1097 AHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQ 1156 T P P KET+P+ + T + ++ A P P P+ A T + Sbjct: 558 KPAPTTPKEPAPTTP--KETAPTTPKKL-TPTTPEKLA-PTTPEKPAPTTPEELAPTTPE 613 Query: 1157 QQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQ---- 1212 + + PAP+ + + +P++ + APT P T + + Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 673 Query: 1213 ---------SPQNSFPAAQQTVFTIHPSHV---QPAYTNP----PHMAHVPQAHVQSGMV 1256 +P+ P T P+ +PA T P P P Sbjct: 674 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 733 Query: 1257 PSHPTAHAPMMLMTTQP--PGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307 P+ P AP L P P P P STT+ P T P A Sbjct: 734 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 786 Score = 60.5 bits (145), Expect = 1e-08 Identities = 116/620 (18%), Positives = 210/620 (33%), Gaps = 67/620 (10%) Query: 449 ESSAQYKARVALENDDRSEEEKYTAV---QRNSSEREGHSINTRENKYIPPGQR------ 499 E+S +E + + K T+ ++ +S +E SI K + P + Sbjct: 232 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 291 Query: 500 -NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPS 558 E + G +P+ P + P+ +T P + + + P P+ Sbjct: 292 PKAETTTKGPAL-TTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPT 343 Query: 559 PS-SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPA-PVSTMPKRMS 616 + S P + + P + A T + P+ ++ P + SA +P P T PK+ + Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403 Query: 617 SEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPP--VARTSPSGGTWS 674 P +P + P + + + E P A T P A T+P + Sbjct: 404 PTTPKEPAPTTPKEP---TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460 Query: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASP 734 + P + K P +P++ + T S P A PT + P P+P + Sbjct: 461 TPKEPAP-TTTKEPSPTTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTT 516 Query: 735 ASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEHRK 792 TP A + ++ +P KE P E +P+ +K +P Sbjct: 517 KEPAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTKKP----APTTP---- 564 Query: 793 QIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNC 852 K P T+ + + L EK +K P+ + + Sbjct: 565 --------KEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEP 615 Query: 853 TSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTS----SPACKQEKDDKEEKKDAAEQ 908 T + + +P+ + NT + P + T+ +P +E K A Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675 Query: 909 VRK----STLNPNAKEFNPRSFSQPKPST----TPTSPRPQAQPSPSMVGHQQP-TPVYT 959 +++ + P KE P + +P +T PT+P+ A +P P P T Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735 Query: 960 QPVCFAP-NMMYPVPVSP-GVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM 1017 P AP + P P +P P P T + + P P++ + Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795 Query: 1018 HPASAAGPPIAATPPAYSTQ 1037 P TPP +++ Sbjct: 796 TTPKKPAPTTPETPPPTTSE 815 Score = 58.9 bits (141), Expect = 3e-08 Identities = 91/442 (20%), Positives = 143/442 (32%), Gaps = 55/442 (12%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMP 612 PSP +P P+ +S P + A T T+ P PS P+ PAP T P Sbjct: 473 PSPT-TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-----PTTTKEPAP--TTP 524 Query: 613 KRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGT 672 K + P + +P + P + P+ T A T+P Sbjct: 525 KEPAPTTPKKPAPTTPKEPAP----------------TTPKEPAPTTTKKPAPTTPKEPA 568 Query: 673 WSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPA 732 ++ P +PK P +P + TP P +P+ T P P P Sbjct: 569 PTTPKETAP-TTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626 Query: 733 SPASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEH 790 +P + TP A + ++ +P KE P ET+P+ KG +P + Sbjct: 627 TPKAAAPNTPKEPAPTT----PKEPAPTTPKEPAPTTPKETAPT----TPKGTAPTTLKE 678 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K + L P++T E DK P+ + Sbjct: 679 PAPTTPKKPAPKE--LAPTTTKEPTSTTC--------------DKPAPTTPKGTAPTTPK 722 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 + K +P+ T + P + + A Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782 Query: 911 KSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM-M 969 K T KE P + +P P TTP +P P + ++PT ++ P P + Sbjct: 783 KETAPTTPKEPAPTTPKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841 Query: 970 YPVPVSPGVQPLYP-IPMTPMP 990 P P + P P +P T P Sbjct: 842 EPTPKALENSPKEPGVPTTKTP 863 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 68.2 bits (165), Expect = 5e-11 Identities = 84/412 (20%), Positives = 158/412 (38%), Gaps = 49/412 (11%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPP---------SHPSAHG 603 P+P P + ++ P + P+ PT P+ P +P P++ Sbjct: 688 PAPTTPKEPAPTTPKETAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745 Query: 604 SPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPV 663 P T PK + P +P + P + +G+ + L+ + P + A + Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKEL 802 Query: 664 ARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMP 723 A T+ G T ++ P +PK P +P++ + TP P +P+ T V+ P Sbjct: 803 APTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTP 860 Query: 724 IPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGI 783 PT + + + TP A+ + +NSP KE P +P+ +K Sbjct: 861 TTTKEPTTIHKSPDES-TPELSAEPT--PKALENSP---KEPGVPTTKTPAATK------ 908 Query: 784 SPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDS 843 P ++ K K + D R P +T+ + EK+ + S Sbjct: 909 -PEMTTTAKD----KTTERDLRTTPETTTAAPKMTKETATTTEKTTE------------S 951 Query: 844 FIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKK 903 I +++ TS +++ +P ++ + T P+VT+ ++ + ++ + K Sbjct: 952 KITATTTQVTSTTTQDTTPFKITTLKTTT---LAPKVTTTKKTITTTEIMNKPEETAKPK 1008 Query: 904 DAAEQVRKSTLNPNAKEFNPRS-FSQPKPSTTPTSPRPQAQPSPSMVGHQQP 954 D A + +T P P+ S KP T P +P+ P+P + P Sbjct: 1009 DRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1060 Score = 62.0 bits (149), Expect = 4e-09 Identities = 157/773 (20%), Positives = 256/773 (33%), Gaps = 105/773 (13%) Query: 585 PSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSIS 644 P+ PPS PP PS G+ + + KR SPK + +V Sbjct: 110 PTSPPSSKKAPP--PS--GASQTIKSTTKR---------SPKPPNKKKTKKVIESEEITE 156 Query: 645 SGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGN--TP 702 VS N S +++ + +S SS S R K + + ++N TP Sbjct: 157 E--HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 214 Query: 703 SGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGN 762 PV+ +G+ + +P ++ N+ V+ S + ++ P Sbjct: 215 KPPVVDEAGSGLDNGD-----FKVTTPDTSTTQHNK-VSTSPKITTAK--------PINP 260 Query: 763 KENIKPN-ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNK 821 + ++ PN +TS S NK E ++ K+ D + + +S E+ + Sbjct: 261 RPSLPPNSDTSKETSLTVNK---ETTVETKETTTTNKQTSTDGKEKTTSAKET------Q 311 Query: 822 NREGEKSRDLI---KDKIEPSAKDSFIENSSSNCTSGSSKPNSP----SISPSILSNTEH 874 + E ++DL K +P+ K + T P +P S +P + T Sbjct: 312 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 371 Query: 875 KRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTT 934 K P + PA K K+ A K KE P + +P P+TT Sbjct: 372 KSAPTTPKE------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425 Query: 935 PTSPRPQAQPSPSMVGHQQPT------------PVYTQPVCFAPNMMYPVPVSPGVQPLY 982 ++P +P+P+ PT P T P AP P P +P +P Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-KEPAP 484 Query: 983 PIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMH---PASAAGPPIAATPPAYSTQYV 1039 P P P + P P + P + P PA +T Sbjct: 485 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 544 Query: 1040 AYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVS---SSATQYG 1096 A + + P+ + + P +P + AP T +P + + T Sbjct: 545 APTTPKEPSPTTTKEPAPTTPKEPAPTTP------KKPAPTTPKEPAPTTPKEPAPTTTK 598 Query: 1097 AHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQ 1156 T P P KET+P+ + T + ++ A P P P+ A T + Sbjct: 599 KPAPTTPKEPAPTTP--KETAPTTPKKL-TPTTPEKLA-PTTPEKPAPTTPEELAPTTPE 654 Query: 1157 QQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQ---- 1212 + + PAP+ + + +P++ + APT P T + + Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 714 Query: 1213 ---------SPQNSFPAAQQTVFTIHPSHV---QPAYTNP----PHMAHVPQAHVQSGMV 1256 +P+ P T P+ +PA T P P P Sbjct: 715 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 774 Query: 1257 PSHPTAHAPMMLMTTQP--PGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307 P+ P AP L P P P P STT+ P T P A Sbjct: 775 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 827 Score = 60.5 bits (145), Expect = 1e-08 Identities = 116/620 (18%), Positives = 210/620 (33%), Gaps = 67/620 (10%) Query: 449 ESSAQYKARVALENDDRSEEEKYTAV---QRNSSEREGHSINTRENKYIPPGQR------ 499 E+S +E + + K T+ ++ +S +E SI K + P + Sbjct: 273 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 332 Query: 500 -NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPS 558 E + G +P+ P + P+ +T P + + + P P+ Sbjct: 333 PKAETTTKGPAL-TTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPT 384 Query: 559 PS-SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPA-PVSTMPKRMS 616 + S P + + P + A T + P+ ++ P + SA +P P T PK+ + Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444 Query: 617 SEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPP--VARTSPSGGTWS 674 P +P + P + + + E P A T P A T+P + Sbjct: 445 PTTPKEPAPTTPKEP---TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501 Query: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASP 734 + P + K P +P++ + T S P A PT + P P+P + Sbjct: 502 TPKEPAP-TTTKEPSPTTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTT 557 Query: 735 ASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEHRK 792 TP A + ++ +P KE P E +P+ +K +P Sbjct: 558 KEPAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTKKP----APTTP---- 605 Query: 793 QIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNC 852 K P T+ + + L EK +K P+ + + Sbjct: 606 --------KEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEP 656 Query: 853 TSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTS----SPACKQEKDDKEEKKDAAEQ 908 T + + +P+ + NT + P + T+ +P +E K A Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 716 Query: 909 VRK----STLNPNAKEFNPRSFSQPKPST----TPTSPRPQAQPSPSMVGHQQP-TPVYT 959 +++ + P KE P + +P +T PT+P+ A +P P P T Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776 Query: 960 QPVCFAP-NMMYPVPVSP-GVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMM 1017 P AP + P P +P P P T + + P P++ + Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836 Query: 1018 HPASAAGPPIAATPPAYSTQ 1037 P TPP +++ Sbjct: 837 TTPKKPAPTTPETPPPTTSE 856 Score = 58.9 bits (141), Expect = 3e-08 Identities = 91/442 (20%), Positives = 143/442 (32%), Gaps = 55/442 (12%) Query: 553 PSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMP 612 PSP +P P+ +S P + A T T+ P PS P+ PAP T P Sbjct: 514 PSPT-TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-----PTTTKEPAP--TTP 565 Query: 613 KRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGT 672 K + P + +P + P + P+ T A T+P Sbjct: 566 KEPAPTTPKKPAPTTPKEPAP----------------TTPKEPAPTTTKKPAPTTPKEPA 609 Query: 673 WSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPA 732 ++ P +PK P +P + TP P +P+ T P P P Sbjct: 610 PTTPKETAP-TTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 667 Query: 733 SPASNRAVTPSSEAKDSRLQDQRQNSPAGNKE--NIKPNETSPSFSKAENKGISPVVSEH 790 +P + TP A + ++ +P KE P ET+P+ KG +P + Sbjct: 668 TPKAAAPNTPKEPAPTT----PKEPAPTTPKEPAPTTPKETAPT----TPKGTAPTTLKE 719 Query: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 K + L P++T E DK P+ + Sbjct: 720 PAPTTPKKPAPKE--LAPTTTKEPTSTTC--------------DKPAPTTPKGTAPTTPK 763 Query: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 + K +P+ T + P + + A Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823 Query: 911 KSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM-M 969 K T KE P + +P P TTP +P P + ++PT ++ P P + Sbjct: 824 KETAPTTPKEPAPTTPKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882 Query: 970 YPVPVSPGVQPLYP-IPMTPMP 990 P P + P P +P T P Sbjct: 883 EPTPKALENSPKEPGVPTTKTP 904 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 68.2 bits (165), Expect = 5e-11 Identities = 194/926 (20%), Positives = 311/926 (33%), Gaps = 98/926 (10%) Query: 365 EHKEKDLEPWDAGELTANEELEALEND-VSNGWDPNDMFRYNEENYGVVSTYDSSLSSYT 423 E + + L P ++T EEL + D D R + G ++ + S Sbjct: 832 ERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLK 891 Query: 424 VPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAV----QRNSS 479 V +E SEE +++ + L + + E D EEK V Sbjct: 892 VEIE--TSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRG 949 Query: 480 EREGHSINTRENKYIP-----------PGQRNREVISW----GSGRQNSPRMGQPGSGSM 524 E EG S + + P PG + V S G G SPR Q G + Sbjct: 950 EPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNC 1009 Query: 525 ---PSRSTSHTSDFNPNSGSDQRVVNGGVPWPSP-CPSPSSRPPSRYQSGPNSLPPRAAT 580 P+ S S DQ + +P P P+P +P + QS + PP + Sbjct: 1010 KMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNS-QSQKHLAPPPLLS 1068 Query: 581 PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGR 640 P P +P R +R A +P P + R S + P Sbjct: 1069 PLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPH 1128 Query: 641 GSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGN 700 S S+ + V+ P S+A R+S T VV P L P T + Sbjct: 1129 PSTSTA-QPVTPKPTSQATRSRTNRSSVK--TPEPVVPTAPELQPSTSTDQPVTSEPTSQ 1185 Query: 701 TPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPA 760 G ++ + E V +P A S +++R VT SE + ++ S Sbjct: 1186 VTRG---RKSRSSVKTPETV---VPTALELQPSTSTDRPVT--SEPTSQATRGRKNRSSV 1237 Query: 761 GNKENIKPN--ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFR-----------LQ 807 E + P E PS S + PV SE Q +K ++ + L+ Sbjct: 1238 KTPEPVVPTAPELQPSTSTDQ-----PVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELR 1292 Query: 808 PSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPS 867 PS++++ +R ++ K + + E S T P S + Sbjct: 1293 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTR 1352 Query: 868 ILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFS 927 +N + PE T P+ E+ E A + RK+ RS Sbjct: 1353 SRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKN-----------RSSG 1401 Query: 928 QPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYP---VPVSPGVQPLYPI 984 + + PT+P+ + S +PT T+ ++ P VP +P +QP Sbjct: 1402 KTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTST 1461 Query: 985 --PMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYS 1042 P+TP P +QA R + + + + + +++ P+ + P + +T+ Sbjct: 1462 DQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNR 1521 Query: 1043 PQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTH 1102 + +V P Q PV P + A G + S+ + Sbjct: 1522 SSVKTPETVVPAAPELQPS-TSTDQPVTP------EPTSRATRGRTNRSSVKTPESIVPI 1574 Query: 1103 AMYACPKLPYNKETSP---SFYFAISTGSLAQQYAHPNATLHPHTPHP--------QPSA 1151 A P N+ +P S T + + P P PHP P Sbjct: 1575 APELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPE-PHPTTSTDQPVTPKL 1633 Query: 1152 TPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNT 1211 T ++ + S P PV+ AA L +P QS A +A S T S+T Sbjct: 1634 TSRATRRKTNRSSVKTPKPVE----PAASDLEPFTPTDQSVTPEA-IAQGGQSKTLRSST 1688 Query: 1212 --QSPQNSFPAAQQTVFTIHPSHVQP 1235 P + P Q V T P +P Sbjct: 1689 VRAMPVPTTPEFQSPVTTDQPISPEP 1714 Score = 62.8 bits (151), Expect = 2e-09 Identities = 195/952 (20%), Positives = 328/952 (34%), Gaps = 160/952 (16%) Query: 425 PLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGH 484 PLER+ + +R+ EE+ Q + + L D +E + S ER+ Sbjct: 830 PLERETEKLLPERQTDVTG-EEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRE 888 Query: 485 SINTR------------ENKYIPPGQRNREVISWGSGRQNSP-RMGQPGSGSMPSRSTSH 531 S+ + + +P REV + R+ P + + + R T Sbjct: 889 SLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQR 948 Query: 532 TSDFNPNSGSDQRVVNGGVPWPSP------CPSPSSRP-PSRYQSGPNSLPPRAATPTR- 583 P GS + P P P P P+S P PS QSG P +P R Sbjct: 949 GE---PEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSP---VSPRRH 1002 Query: 584 ---------PPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSP---KAQRHP 631 PP+ SR R S +P + +P + P P ++Q+H Sbjct: 1003 QKGLLNCKMPPAEKASR-IRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHL 1061 Query: 632 RNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR 691 + + P + P V +T G + L P +P+ Sbjct: 1062 APPPLLS---------------PLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPK 1106 Query: 692 SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRL 751 + S TP A+P+ P+ + A P+ TP P+S+A SR Sbjct: 1107 IRTRKSSRMTPFPATSAAPEPH--PSTSTAQPV-----TPK---------PTSQATRSRT 1150 Query: 752 QDQRQNSPAGNKENIKPN--ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFR---- 805 +P E + P E PS S + PV SE Q+ +K ++ + Sbjct: 1151 NRSSVKTP----EPVVPTAPELQPSTSTDQ-----PVTSEPTSQVTRGRKSRSSVKTPET 1201 Query: 806 -------LQPSSTSES--MDQLLNKNREGEKSRDLIK--DKIEPSAKDSFIENSSSNCTS 854 LQPS++++ + ++ G K+R +K + + P+A + ++ S+S Sbjct: 1202 VVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPE--LQPSTSTDQP 1259 Query: 855 GSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTL 914 +S+P + RG + S V+T P + + K T Sbjct: 1260 VTSEPTYQAT-----------RGRKNRSS-VKTPEPVVPTAPELRPSTSTDRPVTPKPTS 1307 Query: 915 NPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYP--- 971 N S P+ + PT+P Q S +PT T+ ++ P Sbjct: 1308 RTTRSRTNMSSVKTPE-TVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPEST 1366 Query: 972 VPVSPGVQPLYPI--PMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAA 1029 VP++P + P P+TP P ++A R + + + + + P+++ P+ Sbjct: 1367 VPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTP 1426 Query: 1030 TPPAYSTQ------YVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHA 1083 P + +T+ V P P +Q P + P P Q + Sbjct: 1427 EPTSQATRGRTNRSSVKTPETVVPTAPELQ--PSTSTDQPVTPEPTSQATRGRTDRSSVK 1484 Query: 1084 QPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPH 1143 P V +A + A T P E + + G + T+ P Sbjct: 1485 TPETVVPTAPELQASASTDQ-------PVTSEPTSR----TTRGRKNRSSVKTPETVVPA 1533 Query: 1144 TPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQ-QQSAIYHAGLAPTP 1202 P QPS T T Q + S + +++ +P+ Q S + + P P Sbjct: 1534 APELQPS-TSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEP 1592 Query: 1203 PSM-----TPASNTQSPQNSFPAAQQ---TVFTIHPSHVQPAYTNPPHMAHVPQAHVQ-- 1252 S T S+ ++P+ P A + T T P V P T+ ++ V+ Sbjct: 1593 TSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQP--VTPKLTSRATRRKTNRSSVKTP 1650 Query: 1253 -------SGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHF 1297 S + P PT + Q GG L S ++ +PV TT F Sbjct: 1651 KPVEPAASDLEPFTPTDQSVTPEAIAQ--GGQSKTLRSSTVRAMPVPTTPEF 1700 Score = 62.4 bits (150), Expect = 3e-09 Identities = 151/736 (20%), Positives = 252/736 (34%), Gaps = 79/736 (10%) Query: 518 QPGSGSMPSRS-TSHTSDFNPNSGSDQRVVNGGVPWPS----PCPSPSSRPPSRYQSGPN 572 Q GS P +S F+P R + P+P+ P P PS+ P Sbjct: 1083 QDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPT 1142 Query: 573 SLPPRAATPTRPPSRP-PSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHP 631 S R+ T P P P+ P PS + PV++ P + G R S + + P Sbjct: 1143 SQATRSRTNRSSVKTPEPVVPTAPELQPST-STDQPVTSEPTSQVTRG--RKSRSSVKTP 1199 Query: 632 RNHRVSAGRGSISSGLEF-VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRP 690 +A S+ + V+ P S+A R+S T VV P L P T Sbjct: 1200 ETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVK--TPEPVVPTAPELQPSTSTD 1257 Query: 691 RSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSR 750 + G ++ + E V +P A S +++R VTP ++ +R Sbjct: 1258 QPVTSEPTYQATRG---RKNRSSVKTPEPV---VPTAPELRPSTSTDRPVTPKPTSRTTR 1311 Query: 751 LQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPV----VSEHRKQIDDLKKFKNDFRL 806 + S E + P S + ++ ++P + R + +K ++ + Sbjct: 1312 --SRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPI 1369 Query: 807 QPS-STSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSIS 865 P S S +Q + +R +N SS T + P +P + Sbjct: 1370 APELPPSTSTEQPVTPEPTSRATRGR--------------KNRSSGKTPETLVPTAPKLE 1415 Query: 866 PSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNP-- 923 PS ++T+ PE TSQ T + E A +++ ST P Sbjct: 1416 PS--TSTDQPVTPEPTSQA--TRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTS 1471 Query: 924 --------RSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVS 975 RS + + PT+P QA S +PT T+ ++ P V Sbjct: 1472 QATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVV 1531 Query: 976 PGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAM-----MHPASAAGPPIAAT 1030 P L P T PV T RA + + +S + + P+++ + Sbjct: 1532 PAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPE 1591 Query: 1031 PPAYSTQYVAYSPQQFPNQPLVQHV--PHYQSQHPHVYSPVI-------QGNARMMAPPT 1081 P + +T+ +P+V PH + +P + + N + P Sbjct: 1592 PTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPK 1651 Query: 1082 HAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLH 1141 +P +S + +Q+ A + +K S A+ + ++ P T Sbjct: 1652 PVEP--AASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPT-TPEFQSPVTTDQ 1708 Query: 1142 PHTPHP--QPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLA 1199 P +P P QPS ++Q G +P+ H A L Q S G Sbjct: 1709 PISPEPITQPSCI---KRQRAAGNPGSLAAPIDHKPCSAP----LEPKSQASRNQRWGAV 1761 Query: 1200 PTPPSMTPASNTQSPQ 1215 S+T SPQ Sbjct: 1762 RAAESLTAIPEPASPQ 1777 Score = 51.6 bits (122), Expect = 5e-06 Identities = 147/776 (18%), Positives = 246/776 (31%), Gaps = 107/776 (13%) Query: 31 LQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG 90 L+R +R GG + A+ P P PG P SA GS G G+ P Sbjct: 942 LERDTQRGEPEGG--SQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGS--PV 997 Query: 91 SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRP 150 S PR LL P A A+ RA+ +R L P P P Sbjct: 998 S---------PRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAP 1048 Query: 151 -------------ACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVR 197 A P+ PL S+KP ++ +Q Q+ + + +P +R Sbjct: 1049 PQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIR 1108 Query: 198 KPGGSGLLASPA--AAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQS 255 S + PA AAP P S+ ++ T + A S R + + +P + Sbjct: 1109 TRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV---KTPEPVVPTA 1165 Query: 256 TISFDGIYANMRMVHILTSVV--GSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKST 313 + + TS V G K VK P E ++ Sbjct: 1166 PELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTS 1225 Query: 314 ESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEP 373 +++ G K + K + VV ++ S + T G ++ Sbjct: 1226 QATRGRKNRSSV-----KTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKT 1280 Query: 374 WDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEE 433 + TA E + D P + N V T ++ VP + Sbjct: 1281 PEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET-----VVPTAPE---- 1331 Query: 434 FLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKY 493 L+ +Q +S ++R + + E A + S + Sbjct: 1332 -LQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSR 1390 Query: 494 IPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWP 553 G++NR SG P P++ +DQ V Sbjct: 1391 ATRGRKNR------------------SSGKTPETLVPTAPKLEPSTSTDQPVT------- 1425 Query: 554 SPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPK 613 P P+S+ + + P PT P +P + +P +P P S + Sbjct: 1426 ---PEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPV-------TPEPTSQATR 1475 Query: 614 ----RMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPS 669 R S + P + P A + +S + V+ P S R+S Sbjct: 1476 GRTDRSSVKTPETVVPTAPELQAS----------ASTDQPVTSEPTSRTTRGRKNRSSVK 1525 Query: 670 GGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASP 729 T +VV P L P T + G + ++ + E++ +P A Sbjct: 1526 --TPETVVPAAPELQPSTSTDQPVTPEPTSRATRG---RTNRSSVKTPESI---VPIAPE 1577 Query: 730 TPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISP 785 S + N+ VTP ++ +R + R S E + P P + + ++ ++P Sbjct: 1578 LQPSTSRNQLVTPEPTSRATRCRTNR--SSVKTPEPVVPTAPEPHPTTSTDQPVTP 1631 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 68.2 bits (165), Expect = 5e-11 Identities = 127/630 (20%), Positives = 202/630 (32%), Gaps = 93/630 (14%) Query: 518 QPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPR 577 QPG G +P++ P S Q+ G PS P P+ PP Q GP PP+ Sbjct: 443 QPGPGKIPAQQAG------PGKTSAQQT--GPTKPPSQLPGPAKPPPQ--QPGPAKPPPQ 492 Query: 578 AATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVS 637 +PPS+ P PP P P P++ S PP P + + P + S Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPG------PAKPSPQQPGSTKPPSQQPGSAK-PSAQQPS 545 Query: 638 AGRGSISSGLEFVSHNPPSEAATPPV----ARTSPSGGTWSSVVSGVPRLSPKTHRPRSP 693 + S + VS + PP A+ PS G ++ H P Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKA 605 Query: 694 RQNSI-----------GNTPS------------------------GPVLASPQ-----AG 713 N+ G P+ PV +SPQ A Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665 Query: 714 IIPTEAVAMPIPAASPTP----ASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN 769 + T AV+ P T A+P + + P + ++ + K P Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725 Query: 770 ETS---------PSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLN 820 S PS ++K +PV + KQ +K + ++T + Sbjct: 726 ADSLSKPAPPKEPSVPSEQDK--APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783 Query: 821 KNREGEKSRDLIK-DKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPE 879 +++ EK+ +K D +PS SF S P+ I+S+ GP Sbjct: 784 QSQAEEKTTPPLKTDSAKPS--QSFPPTGEKVSPFDSKAIPRPASDSKIISHP----GPS 837 Query: 880 VTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPR 939 S+G + P K+E+ K + K + + K + PR + T SP+ Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897 Query: 940 PQAQPS------PSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQ 993 PQ Q S+ + P Q + + L P P +Q Sbjct: 898 PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957 Query: 994 AKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQ 1053 + + P Q Q A P + P T+ +P +P + Sbjct: 958 SGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK----APAAEKLEPKAE 1013 Query: 1054 HVPHYQSQHPHVYSPVIQGNARMMAPPTHA 1083 P + P I+ + + A P A Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043 Score = 62.4 bits (150), Expect = 3e-09 Identities = 213/988 (21%), Positives = 320/988 (32%), Gaps = 222/988 (22%) Query: 420 SSYTVPLERDNSEEFLKREARANQLA---EEIESSAQYKARV-------ALENDDRSEEE 469 S T+ L+ S LK E +++ + E+ + + + V + + + S+EE Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEE 188 Query: 470 ---KYTAVQRNSSEREG---HSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGS 523 K VQ+ + EG + + K IP Q G GR + G P S S Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQ--------GPGRDPLQQDGTPKSIS 240 Query: 524 MPSRSTSHTSDFNPNSGSDQRVVNGGVPWPS------PCPSPSSRPPSRYQS-------- 569 S+ P +G + + G P P +SRP ++ Sbjct: 241 --SQQPEKIKSQPPGTG---KPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295 Query: 570 ----GPNSLPPRAATPTRPPSRPPSR------PSRPPSHPSAHGSPAPVSTMPKRMSSEG 619 P+ P + TP +PP++ P P++PP+ PS G P++ P + Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS--GLTKPLAQQPGTVK--- 350 Query: 620 PPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG 679 PP P + P A + +G E PS P A P G V Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSE-----KPSSEQPGPKALAQPPG------VGK 399 Query: 680 VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVA-------MPIPAASPTPA 732 P P +P + + + P L SP PT+ +P A P Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459 Query: 733 SPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRK 792 S P S+ +Q PA KP P +K ++ P ++ Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPA------KPPPQQPGSAKPPSQ--QPGSTKPPP 511 Query: 793 QIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPS-AKDSFIENSSSN 851 Q QP S Q + ++ +PS AK S +++ Sbjct: 512 Q-------------QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558 Query: 852 CTSGSSKP-NSPSISPSILSNTEHKRGPEVTSQGV-QTSSPACKQEKDDKEEKKDAAEQV 909 +GS KP P++SPS K+ P SQG+ +T P C + E E+ Sbjct: 559 SQTGSGKPLQPPTVSPSA------KQPP---SQGLPKTICPLC----NTTELLLHVPEKA 605 Query: 910 RKSTLNPNAKEFNPRSFSQPKPSTTPTSP--RPQAQPSPSMVGHQQPTPVYTQPVCFAPN 967 +T P P T Q ++ G P P QP Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL---- 661 Query: 968 MMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPI 1027 PV + V P P P A + + P+ ++ P P + Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP---------PPLVKQPTL 712 Query: 1028 AATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGL 1087 +P A + Q P P VP Q + P Q +M+ P T L Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ--PKMVKPTT----DL 766 Query: 1088 VSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHP 1147 VSSS+ P +P +K S A++ P L + P Sbjct: 767 VSSSSAT-----------TKPDIPSSK-----------VQSQAEEKTTP--PLKTDSAKP 802 Query: 1148 QPSATPTGQQQSQHGG-------------SHPAPS----------PVQHHQHQAAQALHL 1184 S PTG++ S SHP PS PVQ + + +A Sbjct: 803 SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ-KKEEPKKAQTK 861 Query: 1185 ASPQQQSAIYHAGLAPTPPSMTPASNTQSP---QNSFPAAQQTVFTIHPSHVQPAYTNPP 1241 SP+ + G +PTPP P + P Q+ P Q F+++ + A + P Sbjct: 862 MSPKPDAKPMPKG-SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920 Query: 1242 --------------------------HMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPP- 1274 A P H QSG P P AP +QPP Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG--PGAPMKQAP---APSQPPT 975 Query: 1275 -GGPQAALAQSALQP---IPVSTTAHFP 1298 GP + Q+ P IPV P Sbjct: 976 SQGPPKSTGQAPPAPAKSIPVKKETKAP 1003 Score = 58.9 bits (141), Expect = 3e-08 Identities = 92/402 (22%), Positives = 140/402 (34%), Gaps = 81/402 (20%) Query: 537 PNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGP---NSLPPRAATPTRPPSRPPSRPS 593 P SD ++++ P PSS + Q P P +A T P Sbjct: 822 PRPASDSKIISH--------PGPSSESKGQKQVDPVQKKEEPKKAQTKMSP--------- 864 Query: 594 RPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHN 653 +P + P GSP P P + P+ SPK Q R R S GSI+ Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR--RFSLNLGSITDA------- 915 Query: 654 PPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAG 713 P S+ TP T G +S+ S L +P Q SGP QA Sbjct: 916 PKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ-------SGPGAPMKQA- 967 Query: 714 IIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSP 773 P P+ PT P + P + AK ++ + + +PA K K E +P Sbjct: 968 ---------PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK-APAAEKLEPKA-EQAP 1016 Query: 774 SFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIK 833 + + E + P + + + + +K +L+ S ES L K+ I Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLC-------KTELNIG 1069 Query: 834 DKIEPSAKD-SFIENSSSNCTSGSSKPNSPSISPSILSNTEHKR---------------- 876 K P+ + +N N + P+ I + N + +R Sbjct: 1070 SKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAP 1129 Query: 877 -GPEVTSQGVQTSS--------PACKQEKDDKEEKKDAAEQV 909 GP+ + V T S P K K ++E K AE+V Sbjct: 1130 SGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV 1171 Score = 57.8 bits (138), Expect = 7e-08 Identities = 148/622 (23%), Positives = 207/622 (33%), Gaps = 109/622 (17%) Query: 708 ASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRL--QDQRQNSPAGNKEN 765 AS + +P A + A S+ A+ EA S+L +++RQ + ++ Sbjct: 5 ASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ 64 Query: 766 IKPNETSPSFSKAENKGISPVVSEHRKQ-IDDLKKFKNDFRLQPSSTSESMDQLLNKNRE 824 P + P + AE+ S HRKQ +D K R P L+K+R Sbjct: 65 GLPKGSVPP-AAAESP------SMHRKQELDSSHPPKQSGR--PPDPGRPAQPGLSKSRT 115 Query: 825 GEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQG 884 + R ++ P S I S + + + S+ P LS S Sbjct: 116 TDTFRS---EQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN---ALSAVSSV 169 Query: 885 VQTSSP--ACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRP-- 940 V +P + +EE + V+K P P PKP P Sbjct: 170 VNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDP 229 Query: 941 -QAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGV-QPLYPIPMTPMPVNQAKTYR 998 Q +P + QQP + +QP PG +P+ TP + + Sbjct: 230 LQQDGTPKSISSQQPEKIKSQP--------------PGTGKPIQGPTQTPQTDHAKLPLQ 275 Query: 999 AVPNMPQQRQDQHHQSAMMHPA--SAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVP 1056 + PQ +Q + + P+ S + PPI Q P +P Q Sbjct: 276 RDASRPQTKQADIVRGESVKPSLPSPSKPPIQ---------------QPTPGKPPAQQPG 320 Query: 1057 HYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKET 1116 H +SQ P P Q + + P QPG V G + P P Sbjct: 321 HEKSQ-PGPAKPPAQPSG--LTKPLAQQPGTVKPPVQPPGTTKP-------PAQPLGPAK 370 Query: 1117 SPSFYFAISTGSL--AQQYAHPNATLHP----HTPHPQPS-ATPTGQQ------------ 1157 P A TGS + + P A P TP QP A P QQ Sbjct: 371 PP----AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426 Query: 1158 -QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPT-PPSMTPASNTQSPQ 1215 QS P +PVQ A A P + SA PT PPS P PQ Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQ-AGPGKTSA---QQTGPTKPPSQLPGPAKPPPQ 482 Query: 1216 NSFPAAQ--QTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQP 1273 PA Q + P QP T PP PQ Q G P +P +T+P Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPP-----PQ---QPG-----PAKPSPQQPGSTKP 529 Query: 1274 PGGPQAALAQSALQPIPVSTTA 1295 P + SA QP P +A Sbjct: 530 PSQQPGSAKPSAQQPSPAKPSA 551 Score = 56.6 bits (135), Expect = 2e-07 Identities = 125/599 (20%), Positives = 203/599 (33%), Gaps = 70/599 (11%) Query: 657 EAATPPVARTSPSGGTWSSVVSG-VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGII 715 + + PP A SPS + S P+ S + P P Q + + + S Q Sbjct: 68 KGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK--- 124 Query: 716 PTEAVAMPIPAASPTPASPASNRAVTP-SSEAKDSRLQDQRQNSPAGNKENIKPNETSPS 774 +P SP+ S +++ T E K S + A + + N+ +P Sbjct: 125 --------LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNP- 175 Query: 775 FSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKD 834 F + S + ++++ ++ K + ++P + + + G RD ++ Sbjct: 176 FDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPG---RDPLQQ 232 Query: 835 KIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQ 894 P + S + G+ KP P+ T+H + P Sbjct: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQ---GPTQTPQTDHAKLP---------------L 274 Query: 895 EKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSP--RPQAQPSPSMVGHQ 952 ++D + A+ VR ++ P+ + QP P P ++QP P+ Q Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ 334 Query: 953 Q---PTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQD 1009 P+ QP P + P P QPL P P Q + + P + Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP---AKPPAQQTGSEKPSSEQPGPKAL 391 Query: 1010 QHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPV 1069 PA GP A PP TQ V +P+ QP +Q ++ P Sbjct: 392 AQPPGVGKTPAQQPGP---AKPP---TQQVG-TPKPLAQQPGLQS----PAKAPGPTKTP 440 Query: 1070 IQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSL 1129 +Q P A PG +SA Q G + + P P ++ P+ GS Sbjct: 441 VQQPGPGKIPAQQAGPG--KTSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPPPQQPGSA 497 Query: 1130 AQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQ 1189 P +T P P A P+ QQ GS PS +AQ A P Sbjct: 498 KPPSQQPGSTKPP--PQQPGPAKPSPQQP----GSTKPPSQQPGSAKPSAQQPSPAKPSA 551 Query: 1190 QSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQ 1248 Q + P S T + P P+A+Q P + P + HVP+ Sbjct: 552 QQ-------STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE 603 Score = 52.0 bits (123), Expect = 4e-06 Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 32/217 (14%) Query: 34 PARRSG-RGGGGAAPGPYPSAAPP--------PPGPGPPPSRQSSPPSASDCFGSNGNGG 84 PA+++G PGP A PP PGP PP++Q P Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL---------- 421 Query: 85 GAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPA 144 A +PG + GP + P+ PG +A P + S ++G + +P Sbjct: 422 -AQQPGLQSPAKAPGPTKT------PVQQPGPGKIPAQQAGP--GKTSAQQTGPT--KPP 470 Query: 145 PGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGL 204 P PA P P + P QQ + QQ + QQP PA + ++PG + Sbjct: 471 SQLPGPAKPPPQQP-GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529 Query: 205 LASPAAAPSPSSSSVSSSSATAPSSV-VAATSGGGRP 240 + + PS+ S + +A S + +G G+P Sbjct: 530 PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566 Score = 49.7 bits (117), Expect = 2e-05 Identities = 54/198 (27%), Positives = 71/198 (35%), Gaps = 33/198 (16%) Query: 35 ARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRL 94 A++ G APGP + P GPG P++Q+ P S G +P S+ Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQP-GPGKIPAQQAGPGKTS------AQQTGPTKPPSQ-- 472 Query: 95 LGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEP 154 L GP +P P PG PA P P A PP +P P P PA Sbjct: 473 --LPGPAKP------PPQQPG--PAKPPPQQP--GSAKPPSQQPGSTKPPPQQPGPA--- 517 Query: 155 VYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPP--PAAANVRKPGGSGLLASPAAAP 212 PQQ + QQ + QQ P P+A KP P P Sbjct: 518 -------KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570 Query: 213 SPSSSSVSSSSATAPSSV 230 + S S+ S P ++ Sbjct: 571 TVSPSAKQPPSQGLPKTI 588 Score = 44.7 bits (104), Expect = 6e-04 Identities = 61/215 (28%), Positives = 74/215 (34%), Gaps = 33/215 (15%) Query: 31 LQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG 90 LQR A R G S P P P PP +Q +P A +PG Sbjct: 274 LQRDASRPQTKQADIVRGE--SVKPSLPSPSKPPIQQPTPGKPP-----------AQQPG 320 Query: 91 SRRLL-GLGGPPRPFVVLLLPLA-SPGA--PPAAP-----TRASPLGARASPPRSGVSLA 141 + G PP L PLA PG PP P A PLG A PP Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSE 379 Query: 142 RPAPGCPRP---ACEPVYGPLTMS----LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAA 194 +P+ P P A P G KP QQ + QQ Q + P P Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Query: 195 NVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS 229 V++PG + PA P +S + T P S Sbjct: 440 PVQQPGPGKI---PAQQAGPGKTSAQQTGPTKPPS 471 Score = 42.0 bits (97), Expect = 0.004 Identities = 50/199 (25%), Positives = 76/199 (38%), Gaps = 19/199 (9%) Query: 553 PSPCPSPSS---RPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVS 609 PS PS SS +P ++S + + P PP PP P PP P P P S Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP----LPPPTS 2432 Query: 610 TMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSI---SSGLEFVSHNPPSEAATPPVART 666 P + + SP P V+ + S+GL + PP + Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492 Query: 667 SPSGGTWS-SVVSGVPRLSPKTHRPRSP----RQNSIGNTPSGPVLASPQA-GIIPTEAV 720 PSG ++ P ++PK P+ P + I P+G L S ++ + Sbjct: 2493 IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552 Query: 721 AMPIPAASPTPASPASNRA 739 +P P +P SP SN++ Sbjct: 2553 KLPSPT---SPLSPHSNKS 2568 Score = 38.9 bits (89), Expect = 0.033 Identities = 47/204 (23%), Positives = 71/204 (34%), Gaps = 50/204 (24%) Query: 49 PYPSAAPPPPGPG-------PPPSRQSSPPSASDCFGSN--------------------- 80 P P +P PPGP P P + P S F N Sbjct: 870 PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929 Query: 81 ---GNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAP-PAAPTRASPLGARASPPRS 136 G G F S L+ G P P + PGAP AP + P ++ P + Sbjct: 930 KLFGFGASIFSQAS-NLISTAGQPGPH-----SQSGPGAPMKQAPAPSQPPTSQGPPKST 983 Query: 137 GVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPP---AA 193 G A PAP P + P L+P + +Q ++ + +++PPP + Sbjct: 984 G--QAPPAPAKSIPVKKETKAPAAEKLEP-------KAEQAPTVKRTETEKKPPPIKDSK 1034 Query: 194 ANVRKPGGSGLLASPAAAPSPSSS 217 + +P + L +P P S+ Sbjct: 1035 SLTAEPQKAVLPTKLEKSPKPEST 1058 Score = 38.9 bits (89), Expect = 0.033 Identities = 86/433 (19%), Positives = 154/433 (35%), Gaps = 41/433 (9%) Query: 612 PKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAAT--PPVARTSPS 669 P+ +S+ PP K ++ P + + ++ +PP P++ SP Sbjct: 3578 PQYLSATSPP----KDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPG 3633 Query: 670 GGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASP 729 S+ V L P P+ + P ASP+ + +++ P P + Sbjct: 3634 KALESAFVPYEKPL-PDDISPQKVLHPDMAKVPP----ASPKTAKMMQRSMSDPKPLS-- 3686 Query: 730 TPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNK-ENIKPNETSPSFSKAENKGISPVVS 788 P + S+RA +E ++ +S A K + PN S S + + Sbjct: 3687 -PTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGT 3745 Query: 789 EHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNRE-GEKSRDLIKDKIEPSAKDSFIE- 846 R++I LQ +D + ++ + +K +L +++ E AK ++E Sbjct: 3746 VSRRRICRTNTMARAKILQ--DIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEM 3803 Query: 847 --NSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTS---------QGVQTSSPACKQE 895 N + + + + ++ EV+S G++ A + E Sbjct: 3804 GINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTE 3863 Query: 896 KDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPK-PSTTPTSPRPQAQPSPSMVGHQQP 954 + E S L P + +S P P+ PTS Q+ + HQQ Sbjct: 3864 FSQFIPPQTQTE----SQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQV 3919 Query: 955 TPVYTQPVCFAPNMMYPVP---VSPGVQPLYPIPMTPMPVNQ---AKTYRAVPNMPQQRQ 1008 +P TQP A M P +P QP Y +P M + Q T P + + Sbjct: 3920 SPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYE 3979 Query: 1009 DQHHQSAMMHPAS 1021 +Q M+ P S Sbjct: 3980 VIRNQPLMIAPVS 3992 Score = 37.0 bits (84), Expect = 0.12 Identities = 19/42 (45%), Positives = 19/42 (45%) Query: 33 RPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSAS 74 RP RS A P P P PPPP P PPP PP S Sbjct: 2391 RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432 Score = 35.0 bits (79), Expect = 0.47 Identities = 64/262 (24%), Positives = 85/262 (32%), Gaps = 53/262 (20%) Query: 929 PKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTP 988 P S+ P PRP + S + Q P P P P P P P P P +P Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPP-------PPPPPPPPPPPPPPPPPLPPPTSP 2433 Query: 989 MPVNQAK--------------TYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAY 1034 P K + AV + + + + + A PP+ PP Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV---PP-- 2488 Query: 1035 STQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSAT- 1093 P P+ + H P S+ P PVI PT P S T Sbjct: 2489 -------KPSSIPSGLVFTHRPE-PSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540 Query: 1094 QYGAHEQTHAMYACPK-----LPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQ 1148 + T A Y P P++ ++SP F + SL + Y TL P Sbjct: 2541 SMTLNLVTSADYKLPSPTSPLSPHSNKSSPRF-----SKSLTETYV--VITL------PS 2587 Query: 1149 PSATPTGQQQSQHGGSHPAPSP 1170 TPT SQ S P SP Sbjct: 2588 EPGTPTDSSASQAITSWPLGSP 2609 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.124 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,650,314 Number of Sequences: 37866 Number of extensions: 4731874 Number of successful extensions: 89649 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 774 Number of HSP's successfully gapped in prelim test: 2736 Number of HSP's that attempted gapping in prelim test: 33840 Number of HSP's gapped (non-prelim): 35277 length of query: 1313 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1199 effective length of database: 13,930,794 effective search space: 16703022006 effective search space used: 16703022006 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.