Search of human proteins with 171184406

Search of human proteins with 171184406

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|171184406 solute carrier family 6 (neurotransmitter
transporter, betaine/GABA), member 12 [Homo sapiens]
         (614 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|171184408 solute carrier family 6 (neurotransmitter transport...  1281   0.0  
gi|171184406 solute carrier family 6 (neurotransmitter transport...  1281   0.0  
gi|171184404 solute carrier family 6 (neurotransmitter transport...  1281   0.0  
gi|21361581 solute carrier family 6 (neurotransmitter transporte...   887   0.0  
gi|7657587 solute carrier family 6 (neurotransmitter transporter...   843   0.0  
gi|197276623 solute carrier family 6 (neurotransmitter transport...   763   0.0  
gi|54607094 solute carrier family 6 (neurotransmitter transporte...   763   0.0  
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi...   671   0.0  
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa...   651   0.0  
gi|188528618 solute carrier family 6 (neurotransmitter transport...   625   e-179
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa...   577   e-164
gi|4557046 solute carrier family 6 member 2 [Homo sapiens]            530   e-150
gi|92859670 solute carrier family 6 (neurotransmitter transporte...   526   e-149
gi|134304856 solute carrier family 6, member 7 [Homo sapiens]         522   e-148
gi|4507041 solute carrier family 6 (neurotransmitter transporter...   515   e-146
gi|4507043 solute carrier family 6 member 4 [Homo sapiens]            513   e-145
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap...   505   e-143
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap...   505   e-143
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap...   505   e-143
gi|6005715 solute carrier family 6 (amino acid transporter), mem...   479   e-135
gi|51468073 solute carrier family 6, member 19 [Homo sapiens]         377   e-104
gi|194018524 solute carrier family 6, member 18 [Homo sapiens]        372   e-103
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s...   354   2e-97
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s...   294   2e-79
gi|58219014 solute carrier family 6, member 17 [Homo sapiens]         289   5e-78
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s...   278   8e-75
gi|197276625 solute carrier family 6 (neurotransmitter transport...   236   6e-62
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ...   209   6e-54
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s...   191   2e-48
gi|55749589 solute carrier family 6, member 16 [Homo sapiens]         166   4e-41

>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score = 1281 bits (3315), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 1   MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW 60
           MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW
Sbjct: 1   MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW 60

Query: 61  RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL 120
           RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL
Sbjct: 61  RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL 120

Query: 121 ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP 180
           ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP
Sbjct: 121 ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP 180

Query: 181 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY 240
           FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
Sbjct: 181 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY 240

Query: 241 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG 300
           FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
Sbjct: 241 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG 300

Query: 301 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP 360
           CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
Sbjct: 301 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP 360

Query: 361 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR 420
           GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
Sbjct: 361 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR 420

Query: 421 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR 480
           RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
Sbjct: 421 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR 480

Query: 481 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW 540
           FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
Sbjct: 481 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW 540

Query: 541 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP 600
           FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
Sbjct: 541 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP 600

Query: 601 TREGLIAGEKETHL 614
           TREGLIAGEKETHL
Sbjct: 601 TREGLIAGEKETHL 614


>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score = 1281 bits (3315), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 1   MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW 60
           MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW
Sbjct: 1   MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW 60

Query: 61  RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL 120
           RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL
Sbjct: 61  RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL 120

Query: 121 ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP 180
           ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP
Sbjct: 121 ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP 180

Query: 181 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY 240
           FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
Sbjct: 181 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY 240

Query: 241 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG 300
           FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
Sbjct: 241 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG 300

Query: 301 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP 360
           CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
Sbjct: 301 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP 360

Query: 361 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR 420
           GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
Sbjct: 361 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR 420

Query: 421 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR 480
           RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
Sbjct: 421 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR 480

Query: 481 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW 540
           FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
Sbjct: 481 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW 540

Query: 541 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP 600
           FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
Sbjct: 541 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP 600

Query: 601 TREGLIAGEKETHL 614
           TREGLIAGEKETHL
Sbjct: 601 TREGLIAGEKETHL 614


>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score = 1281 bits (3315), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 1   MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW 60
           MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW
Sbjct: 1   MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW 60

Query: 61  RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL 120
           RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL
Sbjct: 61  RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL 120

Query: 121 ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP 180
           ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP
Sbjct: 121 ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP 180

Query: 181 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY 240
           FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
Sbjct: 181 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY 240

Query: 241 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG 300
           FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
Sbjct: 241 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG 300

Query: 301 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP 360
           CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
Sbjct: 301 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP 360

Query: 361 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR 420
           GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
Sbjct: 361 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR 420

Query: 421 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR 480
           RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
Sbjct: 421 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR 480

Query: 481 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW 540
           FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
Sbjct: 481 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW 540

Query: 541 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP 600
           FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
Sbjct: 541 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP 600

Query: 601 TREGLIAGEKETHL 614
           TREGLIAGEKETHL
Sbjct: 601 TREGLIAGEKETHL 614


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score =  887 bits (2292), Expect = 0.0
 Identities = 421/589 (71%), Positives = 486/589 (82%), Gaps = 8/589 (1%)

Query: 25  LDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFV 84
           +++++ED   +RG W NKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY +F F 
Sbjct: 21  MEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFT 80

Query: 85  CGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYL 144
           CGIPVF LE ALGQYTSQG VTAWRKICP+F+GIG AS +I   LNVYYII+LAWALFYL
Sbjct: 81  CGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYL 140

Query: 145 FSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIH 204
           FSSFT +LPW  C + WNTEHC +F   +G+   T  EN TSPV+EFWERRVL I+ GI 
Sbjct: 141 FSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTS-ENATSPVIEFWERRVLKISDGIQ 199

Query: 205 DLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAY 264
            LG+LRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLV+LLIRGVTLPGA 
Sbjct: 200 HLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAA 259

Query: 265 QGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCF 324
           QGI +YL P+L RL DPQVWMDAGTQIFFSFAIC GCLTALGSYNKYHNNCY+DCIALCF
Sbjct: 260 QGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCF 319

Query: 325 LNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLF 384
           LNS TSFVAGF +FSILGFMSQEQGVPISEVAESGPGLAFIA+P+AV M+P S LW+C F
Sbjct: 320 LNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCF 379

Query: 385 FIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGG 444
           F M++ LGLDSQFVCVE LVTA +DM+P   RK  RRE+LIL ++V+ +L+GL ++TEGG
Sbjct: 380 FFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGG 439

Query: 445 MYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFL 504
           MY+FQLFDYYA+SG+CLLF+++FE +C++WVYGA RFYDNIEDMIGYRPWPL+K  WLFL
Sbjct: 440 MYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFL 499

Query: 505 TPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGP 564
           TP +C ATFLFSL KYTPL YN  Y YP WG ++GW LALSSMVC+P + +  L   +GP
Sbjct: 500 TPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGP 559

Query: 565 FRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSPTREGLIAGEKETH 613
           FR+R+RQL+ P   LPQ  ++P     AG +   +P    L   E E+H
Sbjct: 560 FRERIRQLMCPAEDLPQ--RNP-----AGPSAPATPRTSLLRLTELESH 601


>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score =  843 bits (2179), Expect = 0.0
 Identities = 389/549 (70%), Positives = 461/549 (83%), Gaps = 3/549 (0%)

Query: 33  VKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFL 92
           V +RG W NK+EFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF IPY +FF  CGIPVFFL
Sbjct: 47  VHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFL 106

Query: 93  EVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152
           E ALGQ+TS+G +T WRK+CPLF+GIG A+ VIE++LNVYYIIILAWA+FYL + FT+EL
Sbjct: 107 ETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTEL 166

Query: 153 PWTTCNNFWNTEHCTDF--LNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLR 210
           PW TC + WNTE+C +F  LN S    V+  +N TSPVMEFWE RVL I+ GI  +G+LR
Sbjct: 167 PWATCGHEWNTENCVEFQKLNVSNYSHVS-LQNATSPVMEFWEHRVLAISDGIEHIGNLR 225

Query: 211 WELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYY 270
           WELALCLL AW ICYFCIWKG KSTGKVVY TATFPY+ML+ILLIRGVTLPGA +GI +Y
Sbjct: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285

Query: 271 LKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATS 330
           L PDL RL DPQVW+DAGTQIFFS+AIC GCLTALGSYN Y+NNCY+DCI LC LNS TS
Sbjct: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345

Query: 331 FVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIF 390
           FVAGF +FS+LGFM+ EQGVPI+EVAESGPGLAFIA+PKAVTMMPLS LW+ LFF+MLIF
Sbjct: 346 FVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIF 405

Query: 391 LGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQL 450
           LGLDSQFVCVE LVTA +DM+P+  R+  RRELLIL ++V+ Y +GL ++TEGGMYIFQL
Sbjct: 406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQL 465

Query: 451 FDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCL 510
           FD YA+SG+CLLF+++FE +CI WVYG++RFYDNIEDMIGYRP  L+K  W+ +TPG+C 
Sbjct: 466 FDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525

Query: 511 ATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLR 570
             F+F L KY PLKYNN+Y YP WGY IGW +ALSSM+C+PL++ IT+ KT G   ++L+
Sbjct: 526 GIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQ 585

Query: 571 QLITPDSSL 579
           +L TP + L
Sbjct: 586 KLTTPSTDL 594


>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  763 bits (1971), Expect = 0.0
 Identities = 354/556 (63%), Positives = 432/556 (77%), Gaps = 2/556 (0%)

Query: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

Query: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146

Query: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWERRVLGI 199
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWER VL +
Sbjct: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL 206

Query: 200 TSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVT 259
           + GI   GSL+W+LALCLLL W++C+FCIWKGV+STGKVVYFTATFP+ ML++LL+RG+T
Sbjct: 207 SPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLT 266

Query: 260 LPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDC 319
           LPGA  GI +YL PD+ RL+DPQVW+DAGTQIFFS+AIC G +T+LGSYNKY  N Y+DC
Sbjct: 267 LPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDC 326

Query: 320 IALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQL 379
           + L  LNS TSFV+GF +FSILGFM+QEQGV I++VAESGPGLAFIA+PKAVTMMPL   
Sbjct: 327 MLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTF 386

Query: 380 WSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFL 439
           WS LFFIML+ LGLDSQFV VE  +T+ +D++P  LRK  RRE+ I  +  + YL+GL +
Sbjct: 387 WSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTM 446

Query: 440 VTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKI 499
           VTEGGMY+FQLFDYYA+SG+CLL+++ FE   I+W+YG D  YD IEDMIGYRP P +K 
Sbjct: 447 VTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKY 506

Query: 500 SWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLL 559
           SW  +TP LC+  F+FSL KY PL YN  YVYP W   +GW LALSSM+CVPL +VI L 
Sbjct: 507 SWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC 566

Query: 560 KTRGPFRKRLRQLITP 575
           +T GPF  R++ L+TP
Sbjct: 567 QTEGPFLVRVKYLLTP 582


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  763 bits (1971), Expect = 0.0
 Identities = 354/556 (63%), Positives = 432/556 (77%), Gaps = 2/556 (0%)

Query: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

Query: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146

Query: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWERRVLGI 199
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWER VL +
Sbjct: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL 206

Query: 200 TSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVT 259
           + GI   GSL+W+LALCLLL W++C+FCIWKGV+STGKVVYFTATFP+ ML++LL+RG+T
Sbjct: 207 SPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLT 266

Query: 260 LPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDC 319
           LPGA  GI +YL PD+ RL+DPQVW+DAGTQIFFS+AIC G +T+LGSYNKY  N Y+DC
Sbjct: 267 LPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDC 326

Query: 320 IALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQL 379
           + L  LNS TSFV+GF +FSILGFM+QEQGV I++VAESGPGLAFIA+PKAVTMMPL   
Sbjct: 327 MLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTF 386

Query: 380 WSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFL 439
           WS LFFIML+ LGLDSQFV VE  +T+ +D++P  LRK  RRE+ I  +  + YL+GL +
Sbjct: 387 WSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTM 446

Query: 440 VTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKI 499
           VTEGGMY+FQLFDYYA+SG+CLL+++ FE   I+W+YG D  YD IEDMIGYRP P +K 
Sbjct: 447 VTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKY 506

Query: 500 SWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLL 559
           SW  +TP LC+  F+FSL KY PL YN  YVYP W   +GW LALSSM+CVPL +VI L 
Sbjct: 507 SWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC 566

Query: 560 KTRGPFRKRLRQLITP 575
           +T GPF  R++ L+TP
Sbjct: 567 QTEGPFLVRVKYLLTP 582


>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
           sapiens]
          Length = 635

 Score =  671 bits (1730), Expect = 0.0
 Identities = 313/551 (56%), Positives = 399/551 (72%), Gaps = 10/551 (1%)

Query: 33  VKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFL 92
           V  R  WT +M+F++S  G  +GLGNVWRFPYLCYKNGGG F IPY +   V GIP+FFL
Sbjct: 49  VPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFL 108

Query: 93  EVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152
           E++LGQ+   GS+  W  ICPLF+G+G AS+VI  Y N YYI++LAW  +YL  SFT+ L
Sbjct: 109 EISLGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTL 167

Query: 153 PWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFT--------SPVMEFWERRVLGITSGIH 204
           PW TC + WNT  C +   H      +   N T        SPV+EFWE +VL ++ G+ 
Sbjct: 168 PWATCGHTWNTPDCVEIFRHEDCANAS-LANLTCDQLADRRSPVIEFWENKVLRLSGGLE 226

Query: 205 DLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAY 264
             G+L WE+ LCLL  WV+ YFC+WKGVKSTGK+VYFTATFPY++LV+LL+RGV LPGA 
Sbjct: 227 VPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGAL 286

Query: 265 QGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCF 324
            GIIYYLKPD  +L  PQVW+DAGTQIFFS+AI  G LTALGSYN+++NNCYKD I L  
Sbjct: 287 DGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILAL 346

Query: 325 LNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLF 384
           +NS TSF AGFVVFSILGFM+ EQGV IS+VAESGPGLAFIA+P+AVT+MP++ LW+ LF
Sbjct: 347 INSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALF 406

Query: 385 FIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGG 444
           F ML+ LGLDSQFV VE  +T  +D+ P       +RE+ +     +C++I L +VT+GG
Sbjct: 407 FFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGG 466

Query: 445 MYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFL 504
           MY+FQLFDYY++SG  LL+ + +E V ++WVYGADRF D+I  MIGYRP P +K  W F 
Sbjct: 467 MYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFF 526

Query: 505 TPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGP 564
           TP +C+  F+F++  Y PL YNN YVYP WG ++GW  ALSSM+CVPL ++  LL+ +G 
Sbjct: 527 TPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGT 586

Query: 565 FRKRLRQLITP 575
             +R + L  P
Sbjct: 587 MAERWQHLTQP 597


>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
           sapiens]
          Length = 625

 Score =  651 bits (1680), Expect = 0.0
 Identities = 307/551 (55%), Positives = 393/551 (71%), Gaps = 20/551 (3%)

Query: 33  VKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFL 92
           V  R  WT +M+F++S  G  +GLGNVWRFPYLCYKNGGG F IPY +   V GIP+FFL
Sbjct: 49  VPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFL 108

Query: 93  EVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152
           E++LGQ+   GS+  W  ICPLF+G+G AS+VI  Y N YYI++LAW  +YL  SFT+ L
Sbjct: 109 EISLGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTL 167

Query: 153 PWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFT--------SPVMEFWERRVLGITSGIH 204
           PW TC + WNT  C +   H      +   N T        SPV+EFWE +VL ++ G+ 
Sbjct: 168 PWATCGHTWNTPDCVEIFRHEDCANAS-LANLTCDQLADRRSPVIEFWENKVLRLSGGLE 226

Query: 205 DLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAY 264
             G+L WE+ LCLL  WV+ YFC+WKGVKSTGK+VYFTATFPY++LV+LL+RGV LPGA 
Sbjct: 227 VPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGAL 286

Query: 265 QGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCF 324
            GIIYYLKPD  +L  PQVW+DAGTQIFFS+AI  G LTALGSYN+++NNCY        
Sbjct: 287 DGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCY-------- 338

Query: 325 LNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLF 384
             + TSF AGFVVFSILGFM+ EQGV IS+VAESGPGLAFIA+P+AVT+MP++ LW+ LF
Sbjct: 339 --NGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALF 396

Query: 385 FIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGG 444
           F ML+ LGLDSQFV VE  +T  +D+ P       +RE+ +     +C++I L +VT+GG
Sbjct: 397 FFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGG 456

Query: 445 MYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFL 504
           MY+FQLFDYY++SG  LL+ + +E V ++WVYGADRF D+I  MIGYRP P +K  W F 
Sbjct: 457 MYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFF 516

Query: 505 TPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGP 564
           TP +C+  F+F++  Y PL YNN YVYP WG ++GW  ALSSM+CVPL ++  LL+ +G 
Sbjct: 517 TPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGT 576

Query: 565 FRKRLRQLITP 575
             +R + L  P
Sbjct: 577 MAERWQHLTQP 587


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score =  625 bits (1613), Expect = e-179
 Identities = 292/585 (49%), Positives = 406/585 (69%), Gaps = 10/585 (1%)

Query: 2   DGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWR 61
           DG+++ +    P  +  P+      Q+    + DR  W  + +F++S  G  IGLGNVWR
Sbjct: 10  DGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWR 69

Query: 62  FPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLA 121
           FPYLC KNGGGAF IPYF+     G+P+F LE +LGQYTS G +  W K+ P+F+G+GLA
Sbjct: 70  FPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLA 128

Query: 122 SVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPF 181
           + V+  +LN+YYI+I++WA++YL++SFT+ LPW  C+N WNT+ C  F N+S   T    
Sbjct: 129 AAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRC--FSNYSMVNTT--- 183

Query: 182 ENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYF 241
            N TS V+EFWER +  +T G+   G +RW LA+ L +AW++ YFCIWKGV  TGKVVYF
Sbjct: 184 -NMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYF 242

Query: 242 TATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGC 301
           +AT+PY+ML+IL  RGVTLPGA +GI++Y+ P+  +L D +VW+DA TQIFFS+ +  G 
Sbjct: 243 SATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGS 302

Query: 302 LTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPG 361
           L ALGSYN +HNN Y+D I +C +NS TS  AGFV+FSI+GFM+      I++VA SGPG
Sbjct: 303 LIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPG 362

Query: 362 LAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRR 421
           LAF+A+P+AVT +P+S LW+ LFF ML+ LG+DSQF  VE  +TA +D +PR LR   RR
Sbjct: 363 LAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLR--NRR 420

Query: 422 ELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRF 481
           EL I  + ++ YLIGL  +T+GG+Y+F+LFDYY++SG+ LLFL  FE V ISW YG +RF
Sbjct: 421 ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF 480

Query: 482 YDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWF 541
           YDNI++M+G RP    K+ W F TP +    F+FS  + TPL   N YV+P WG  +GW 
Sbjct: 481 YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWL 539

Query: 542 LALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHP 586
           +ALSSMV +P ++    L  +G  ++R++ ++ P   + +P+  P
Sbjct: 540 MALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGP 584


>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
           sapiens]
          Length = 520

 Score =  577 bits (1487), Expect = e-164
 Identities = 272/481 (56%), Positives = 348/481 (72%), Gaps = 10/481 (2%)

Query: 103 GSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWN 162
           GS+  W  ICPLF+G+G AS+VI  Y N YYI++LAW  +YL  SFT+ LPW TC + WN
Sbjct: 4   GSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWN 62

Query: 163 TEHCTDFLNHSGAGTVTPFENFT--------SPVMEFWERRVLGITSGIHDLGSLRWELA 214
           T  C +   H      +   N T        SPV+EFWE +VL ++ G+   G+L WE+ 
Sbjct: 63  TPDCVEIFRHEDCANAS-LANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVT 121

Query: 215 LCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPD 274
           LCLL  WV+ YFC+WKGVKSTGK+VYFTATFPY++LV+LL+RGV LPGA  GIIYYLKPD
Sbjct: 122 LCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPD 181

Query: 275 LFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAG 334
             +L  PQVW+DAGTQIFFS+AI  G LTALGSYN+++NNCYKD I L  +NS TSF AG
Sbjct: 182 WSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAG 241

Query: 335 FVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLD 394
           FVVFSILGFM+ EQGV IS+VAESGPGLAFIA+P+AVT+MP++ LW+ LFF ML+ LGLD
Sbjct: 242 FVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLD 301

Query: 395 SQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYY 454
           SQFV VE  +T  +D+ P       +RE+ +     +C++I L +VT+GGMY+FQLFDYY
Sbjct: 302 SQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYY 361

Query: 455 ASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFL 514
           ++SG  LL+ + +E V ++WVYGADRF D+I  MIGYRP P +K  W F TP +C+  F+
Sbjct: 362 SASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFI 421

Query: 515 FSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLIT 574
           F++  Y PL YNN YVYP WG ++GW  ALSSM+CVPL ++  LL+ +G   +R + L  
Sbjct: 422 FNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQ 481

Query: 575 P 575
           P
Sbjct: 482 P 482


>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
          Length = 617

 Score =  530 bits (1365), Expect = e-150
 Identities = 255/553 (46%), Positives = 364/553 (65%), Gaps = 11/553 (1%)

Query: 30  EDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPV 89
           +   + R  W  K++F+LSV G  + L NVWRFPYLCYKNGGGAF IPY +F  + G+P+
Sbjct: 50  DGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPL 109

Query: 90  FFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFT 149
           F++E+ALGQY  +G+ T W KICP F+G+G A ++I  Y+  YY +I+AW+L+YLFSSFT
Sbjct: 110 FYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFT 168

Query: 150 SELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFT-SPVMEFWERRVLGI--TSGIH 204
             LPWT C + WN+ +CTD   LN S  G  T +  +  +P  EF+ER VL +  +SGIH
Sbjct: 169 LNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIH 228

Query: 205 DLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAY 264
           D+G  +W+L LCL++  ++ YF +WKGVK++GKVV+ TAT PY +L +LL+ GVTLPGA 
Sbjct: 229 DIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGAS 288

Query: 265 QGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCF 324
            GI  YL  D +RLK+  VW+DA TQIFFS     G L A  SYNK+ NNCY+D +    
Sbjct: 289 NGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSS 348

Query: 325 LNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLF 384
           +N  TSFV+GF +FSILG+M+ E  V I +VA  G GL FI +P+A++ +  S  W+ +F
Sbjct: 349 INCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVF 408

Query: 385 FIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGG 444
           F+ML+ LGLDS    +E ++T   D F    R    R+L    +    +L+ LF +T+GG
Sbjct: 409 FVMLLALGLDSSMGGMEAVITGLADDFQVLKR---HRKLFTFGVTFSTFLLALFCITKGG 465

Query: 445 MYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFL 504
           +Y+  L D +A +G  +LF  L E + +SW YG DRF ++I+ M+G+RP    ++ W F+
Sbjct: 466 IYVLTLLDTFA-AGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFV 524

Query: 505 TPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGP 564
           +P   L   + S+  + PL Y++ Y++PPW   +GW +ALSSMV VP++V+   L T+G 
Sbjct: 525 SPAFLLFVVVVSIINFKPLTYDD-YIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGS 583

Query: 565 FRKRLRQLITPDS 577
             +RL   ITP++
Sbjct: 584 LWERLAYGITPEN 596


>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
           glycine), member 5 [Homo sapiens]
          Length = 797

 Score =  526 bits (1354), Expect = e-149
 Identities = 270/601 (44%), Positives = 381/601 (63%), Gaps = 41/601 (6%)

Query: 27  QEDE--DQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFV 84
           QEDE  D+ K RG W++K++F+LS+ G  +GLGNVWRFPYL ++NGGGAF IPY +   +
Sbjct: 180 QEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLAL 239

Query: 85  CGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYL 144
            G+P+FFLEV+LGQ+ SQG V+ W+ I P  QG G+A ++I   + +YY +I+ + LFYL
Sbjct: 240 AGLPIFFLEVSLGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNVIICYTLFYL 298

Query: 145 FSSFTSELPWTTCNNFWNTEHCTD------------------FLNHSGAGTVTP---FEN 183
           F+SF S LPW +CNN WNT  C D                    N +   T  P     N
Sbjct: 299 FASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVN 358

Query: 184 FTSPV--------MEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKST 235
           FTS           E+++  VL I++GI   G +RW LALCL LAWVI Y  + KG+K++
Sbjct: 359 FTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTS 418

Query: 236 GKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSF 295
           GKVVYFTATFPY++LVILLIRGVTLPGA  GI Y++ P   +L D  VW DA TQIFFS 
Sbjct: 419 GKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSL 478

Query: 296 AICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEV 355
           +   G L  L SYNK+HNNCY+D + +   NSATS  AGFV+FS++GFM+ E+ V I  V
Sbjct: 479 SAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENV 538

Query: 356 AESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQL 415
           A+ GPG+AF+ +P+A+T +PLS  W+ +FF+ML+ LGLD+ F  +E +VT+  D FP+ L
Sbjct: 539 ADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYL 598

Query: 416 RKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWV 475
           R    + +  L   +  +++G  ++T+GG+Y+FQL D YA+S   L+ +++FE+V IS+V
Sbjct: 599 RT--HKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAAS-YALVIIAIFELVGISYV 655

Query: 476 YGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWG 535
           YG  RF ++IE MIG++P    K+ W F+TP +      FS  ++ P+ Y + Y YP W 
Sbjct: 656 YGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGS-YRYPNWS 714

Query: 536 YSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRN 595
             +GW +   S++ +P+  VI +    G F +RL+ + +     PQP   P L    G  
Sbjct: 715 MVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCS-----PQPDWGPFLAQHRGER 769

Query: 596 F 596
           +
Sbjct: 770 Y 770


>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
          Length = 636

 Score =  522 bits (1345), Expect = e-148
 Identities = 262/552 (47%), Positives = 360/552 (65%), Gaps = 11/552 (1%)

Query: 29  DEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIP 88
           D D    RG WT K++F+LS  G  +GLGNVWRFPY  Y NGGGAF +PYF+   +CGIP
Sbjct: 30  DVDFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIP 89

Query: 89  VFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSF 148
           +FFLE++LGQ++S G +  W KI PLF+G G A ++I   + +YY +I+A+ LFYLF+S 
Sbjct: 90  LFFLELSLGQFSSLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASL 148

Query: 149 TSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFT---SPVMEFWERRVLGI--TSGI 203
           TS+LPW  C N+WNTE C +           P  N T   SP  E+W R VL I  + GI
Sbjct: 149 TSDLPWEHCGNWWNTELCLEHRVSKDGNGALPL-NLTCTVSPSEEYWSRYVLHIQGSQGI 207

Query: 204 HDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGA 263
              G +RW L LCLLLAWVI + CI KGVKS+GKVVYFTATFPYL+L++LL+RGVTLPGA
Sbjct: 208 GSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGA 267

Query: 264 YQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALC 323
           ++GI +YL P    L   +VW++A  QIF+S  +  G L    SYN +H N Y+D   + 
Sbjct: 268 WKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVT 327

Query: 324 FLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCL 383
             N+ TS +AGF +FS+LG+MSQE GVP+ +VA++GPGLAF+ +P+A+TM+PLS  WS L
Sbjct: 328 LGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFL 387

Query: 384 FFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEG 443
           FF ML+ LGLDSQF  +E +VTA  D FP  LR   ++ +    I V  YL+GL L T+G
Sbjct: 388 FFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRP--KKAVFSGLICVAMYLMGLILTTDG 445

Query: 444 GMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLF 503
           GMY   L D Y++S   L+ + +   + ++ VYG  RF  +I  M+G++P    +  WLF
Sbjct: 446 GMYWLVLLDDYSAS-FGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLF 504

Query: 504 LTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRG 563
           L+P   LA  ++S+ KY P +Y + Y +PPW   +G  + L S + +P  +++ +L+  G
Sbjct: 505 LSPATLLALMVYSIVKYQPSEYGS-YRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEG 563

Query: 564 PFRKRLRQLITP 575
              +RL+Q   P
Sbjct: 564 SLWERLQQASRP 575


>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
           dopamine), member 3 [Homo sapiens]
          Length = 620

 Score =  515 bits (1327), Expect = e-146
 Identities = 249/549 (45%), Positives = 354/549 (64%), Gaps = 10/549 (1%)

Query: 32  QVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFF 91
           + +DR  W  K++F+LSV G  + L NVWRFPYLCYKNGGGAF +PY +F  + G+P+F+
Sbjct: 56  EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115

Query: 92  LEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSE 151
           +E+ALGQ+  +G+   W KICP+ +G+G   ++I  Y+  +Y +I+AWAL YLFSSFT+E
Sbjct: 116 MELALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTE 174

Query: 152 LPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENF--TSPVMEFWERRVLGI--TSGIHDLG 207
           LPW  CNN WN+ +C+D      +G  +   +   T+P  E++ER VL +  + GI DLG
Sbjct: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG 234

Query: 208 SLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGI 267
             RW+L  CL+L  V+ YF +WKGVK++GKVV+ TAT PY++L  LL+RGVTLPGA  GI
Sbjct: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294

Query: 268 IYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNS 327
             YL  D +RL +  VW+DA TQ+ FS  +  G L A  SYNK+ NNCY+D I    +NS
Sbjct: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354

Query: 328 ATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIM 387
            TSF +GFVVFS LG+M+Q+  VPI +VA+ GPGL FI +P+A+  +PLS  W+ +FFIM
Sbjct: 355 LTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIM 414

Query: 388 LIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYI 447
           L+ LG+DS    +E ++T  ID F    R    REL  L I +  +L+ LF VT GG+Y+
Sbjct: 415 LLTLGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYV 471

Query: 448 FQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPG 507
           F L D++A +G  +LF  L E + ++W YG  +F D+I+ M G RP    ++ W  ++P 
Sbjct: 472 FTLLDHFA-AGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPC 530

Query: 508 LCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRK 567
             L   + S+  + P  Y   Y++P W  ++GW +A SSM  VP++         G FR+
Sbjct: 531 FLLFVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFRE 589

Query: 568 RLRQLITPD 576
           +L   I P+
Sbjct: 590 KLAYAIAPE 598


>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
          Length = 630

 Score =  513 bits (1321), Expect = e-145
 Identities = 249/561 (44%), Positives = 371/561 (66%), Gaps = 20/561 (3%)

Query: 35  DRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEV 94
           +R  W  K++F+LSV G  + LGNVWRFPY+CY+NGGGAF +PY I     GIP+F++E+
Sbjct: 78  ERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMEL 137

Query: 95  ALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPW 154
           ALGQY   G ++ WRKICP+F+GIG A  +I  Y+  YY  I+AWAL+YL SSFT +LPW
Sbjct: 138 ALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPW 197

Query: 155 TTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGI--TSGIHDLGSLRWE 212
           T+C N WNT +CT++ +      +T   + TSP  EF+ R VL I  + G+ DLG + W+
Sbjct: 198 TSCKNSWNTGNCTNYFSEDN---ITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQ 254

Query: 213 LALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLK 272
           LALC++L + + YF IWKGVK++GKVV+ TATFPY++L +LL+RG TLPGA++G+++YLK
Sbjct: 255 LALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLK 314

Query: 273 PDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFV 332
           P+  +L +  VW+DA  QIFFS     G L A  SYNK++NNCY+D +    +N  TSFV
Sbjct: 315 PNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFV 374

Query: 333 AGFVVFSILGFMSQEQGVPISEVA-ESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFL 391
           +GFV+F++LG+M++ +   +SEVA ++GP L FI + +A+  MP S  ++ +FF+MLI L
Sbjct: 375 SGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITL 434

Query: 392 GLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLF 451
           GLDS F  +E ++TA +D FP    K  RRE  +L + + C+   L  +T GG Y+ +L 
Sbjct: 435 GLDSTFAGLEGVITAVLDEFPHVWAK--RRERFVLAVVITCFFGSLVTLTFGGAYVVKLL 492

Query: 452 DYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCL- 510
           + YA +G  +L ++L E V +SW YG  +F  ++++M+G+ P    +I W+ ++P   L 
Sbjct: 493 EEYA-TGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLF 551

Query: 511 --ATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKR 568
              +FL S  +    +YN    YP W   +G+ +  SS +C+P ++   L+ T G F++R
Sbjct: 552 IICSFLMSPPQLRLFQYN----YPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKER 607

Query: 569 LRQLITPDSSLPQPKQHPCLD 589
           + + ITP++    P + PC D
Sbjct: 608 IIKSITPET----PTEIPCGD 624


>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
           sapiens]
          Length = 633

 Score =  505 bits (1300), Expect = e-143
 Identities = 251/573 (43%), Positives = 363/573 (63%), Gaps = 24/573 (4%)

Query: 18  VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
           VP E  K DQ  +     RG W N++EFVL+  G  +GLGNVWRFPYLCY+NGGGAF  P
Sbjct: 14  VPSEATKRDQNLK-----RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 68

Query: 78  YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
           YFI    CGIP+FF+E++ GQ+ SQG +  WR I P+F+G+G   +V+ +Y+ +YY +++
Sbjct: 69  YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 127

Query: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHS----GAGTVTPFENF--------- 184
             A +Y FSS T  LPW  CNN WNT  C   L+ S    G+       N          
Sbjct: 128 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 187

Query: 185 -TSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTA 243
            TSP  E+W   VL ++  I + G +R  L  CL ++W++ + C+ +GVKS+GKVVYFTA
Sbjct: 188 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTA 247

Query: 244 TFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLT 303
           TFPY++L IL +RGVTL GA+ GI+YYL P   ++ + +VW DA +QIF+S     G L 
Sbjct: 248 TFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 307

Query: 304 ALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLA 363
            + SYNK+HNNCY+D + +   N ATS  AGFV+FSILGFM+   GV +S VA+ GPGLA
Sbjct: 308 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 367

Query: 364 FIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRREL 423
           F+A+P+A+T++P+S LWS LFF MLI LGL +QF  +E LVTA +D    +     ++  
Sbjct: 368 FVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTY 426

Query: 424 LILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYD 483
           + L +AV  +L+G+ L ++ G+Y   L D YA+S   L+ +S    V I ++YG   ++ 
Sbjct: 427 VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQ 485

Query: 484 NIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLA 543
           +I+ M+G+ P    +I W F++P +     +F++ +Y P+ YN+ Y YP W  +IG+ +A
Sbjct: 486 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMA 544

Query: 544 LSSMVCVPLFVVITLLKTRG-PFRKRLRQLITP 575
           LSS++C+PL+ +  L +T G    +RL+    P
Sbjct: 545 LSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 577


>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
           sapiens]
          Length = 706

 Score =  505 bits (1300), Expect = e-143
 Identities = 251/573 (43%), Positives = 363/573 (63%), Gaps = 24/573 (4%)

Query: 18  VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
           VP E  K DQ  +     RG W N++EFVL+  G  +GLGNVWRFPYLCY+NGGGAF  P
Sbjct: 87  VPSEATKRDQNLK-----RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 141

Query: 78  YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
           YFI    CGIP+FF+E++ GQ+ SQG +  WR I P+F+G+G   +V+ +Y+ +YY +++
Sbjct: 142 YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 200

Query: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHS----GAGTVTPFENF--------- 184
             A +Y FSS T  LPW  CNN WNT  C   L+ S    G+       N          
Sbjct: 201 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 260

Query: 185 -TSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTA 243
            TSP  E+W   VL ++  I + G +R  L  CL ++W++ + C+ +GVKS+GKVVYFTA
Sbjct: 261 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTA 320

Query: 244 TFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLT 303
           TFPY++L IL +RGVTL GA+ GI+YYL P   ++ + +VW DA +QIF+S     G L 
Sbjct: 321 TFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 380

Query: 304 ALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLA 363
            + SYNK+HNNCY+D + +   N ATS  AGFV+FSILGFM+   GV +S VA+ GPGLA
Sbjct: 381 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 440

Query: 364 FIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRREL 423
           F+A+P+A+T++P+S LWS LFF MLI LGL +QF  +E LVTA +D    +     ++  
Sbjct: 441 FVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTY 499

Query: 424 LILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYD 483
           + L +AV  +L+G+ L ++ G+Y   L D YA+S   L+ +S    V I ++YG   ++ 
Sbjct: 500 VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQ 558

Query: 484 NIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLA 543
           +I+ M+G+ P    +I W F++P +     +F++ +Y P+ YN+ Y YP W  +IG+ +A
Sbjct: 559 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMA 617

Query: 544 LSSMVCVPLFVVITLLKTRG-PFRKRLRQLITP 575
           LSS++C+PL+ +  L +T G    +RL+    P
Sbjct: 618 LSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 650


>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
           sapiens]
          Length = 652

 Score =  505 bits (1300), Expect = e-143
 Identities = 251/573 (43%), Positives = 363/573 (63%), Gaps = 24/573 (4%)

Query: 18  VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
           VP E  K DQ  +     RG W N++EFVL+  G  +GLGNVWRFPYLCY+NGGGAF  P
Sbjct: 33  VPSEATKRDQNLK-----RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 87

Query: 78  YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
           YFI    CGIP+FF+E++ GQ+ SQG +  WR I P+F+G+G   +V+ +Y+ +YY +++
Sbjct: 88  YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 146

Query: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHS----GAGTVTPFENF--------- 184
             A +Y FSS T  LPW  CNN WNT  C   L+ S    G+       N          
Sbjct: 147 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 206

Query: 185 -TSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTA 243
            TSP  E+W   VL ++  I + G +R  L  CL ++W++ + C+ +GVKS+GKVVYFTA
Sbjct: 207 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTA 266

Query: 244 TFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLT 303
           TFPY++L IL +RGVTL GA+ GI+YYL P   ++ + +VW DA +QIF+S     G L 
Sbjct: 267 TFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 326

Query: 304 ALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLA 363
            + SYNK+HNNCY+D + +   N ATS  AGFV+FSILGFM+   GV +S VA+ GPGLA
Sbjct: 327 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 386

Query: 364 FIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRREL 423
           F+A+P+A+T++P+S LWS LFF MLI LGL +QF  +E LVTA +D    +     ++  
Sbjct: 387 FVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTY 445

Query: 424 LILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYD 483
           + L +AV  +L+G+ L ++ G+Y   L D YA+S   L+ +S    V I ++YG   ++ 
Sbjct: 446 VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQ 504

Query: 484 NIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLA 543
           +I+ M+G+ P    +I W F++P +     +F++ +Y P+ YN+ Y YP W  +IG+ +A
Sbjct: 505 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMA 563

Query: 544 LSSMVCVPLFVVITLLKTRG-PFRKRLRQLITP 575
           LSS++C+PL+ +  L +T G    +RL+    P
Sbjct: 564 LSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 596


>gi|6005715 solute carrier family 6 (amino acid transporter), member
           14 [Homo sapiens]
          Length = 642

 Score =  479 bits (1232), Expect = e-135
 Identities = 246/602 (40%), Positives = 370/602 (61%), Gaps = 40/602 (6%)

Query: 18  VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
           V    E     + D+ +DRG W+ K +++LS+ G  +GLGNVWRFPYL Y NGGGAF IP
Sbjct: 18  VSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIP 77

Query: 78  YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
           Y I   + G+P+FFLE +LGQ+ S G V+ WR I PLFQG+G+  V+I  ++ +YY +I+
Sbjct: 78  YAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVII 136

Query: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCT--DFLNHSGAGTVTP--------------F 181
           A++L+Y+F+SF SELPW  C++ W+ ++C+    + H    TV                 
Sbjct: 137 AYSLYYMFASFQSELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDI 195

Query: 182 ENFTS------------PVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIW 229
            NFT             P  ++W +  L  +SG+++ G + W LALCLLLAW+I    ++
Sbjct: 196 NNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALF 255

Query: 230 KGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYL--KPDLFRLKDPQVWMDA 287
           KG+KS+GKVVYFTA FPY++L+ILL+RG TL GA +GI YY+  + +  +LK+ +VW DA
Sbjct: 256 KGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDA 315

Query: 288 GTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQE 347
            TQIF+S ++  G L AL SYNK+ NNC+ D I +C  N  TS  AGF +FSILG M+  
Sbjct: 316 ATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHI 375

Query: 348 QGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTAS 407
            G  +S+V +SG  LAFIA+P+A+  +P    WS LFF ML+ LGLDSQF  +E + T  
Sbjct: 376 SGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTI 435

Query: 408 IDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLF 467
            D+FP+ ++K   R  + L   ++ +L+GL  VT+ G+Y   L D++  +G  +L  ++ 
Sbjct: 436 QDLFPKVMKK--MRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFC-AGWGILIAAIL 492

Query: 468 EVVCISWVYGADRFYDNIEDMIGYRPWPL---VKISWLFLTPGLCLATFLFSLSKYTPLK 524
           E+V I W+YG +RF ++ E MIG + W      +  W  +TP L +A F++SL ++    
Sbjct: 493 ELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPN 552

Query: 525 YNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSL-PQPK 583
           Y  +  YP WG ++GW + +  ++ +P+  +I +++ +G   +RL     P S+  P  +
Sbjct: 553 YGAI-PYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLE 611

Query: 584 QH 585
           QH
Sbjct: 612 QH 613


>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
          Length = 634

 Score =  377 bits (968), Expect = e-104
 Identities = 214/603 (35%), Positives = 313/603 (51%), Gaps = 81/603 (13%)

Query: 24  KLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFF 83
           +L+  ++++   R +W NK +++L+  G  +GLGNVWRFPYLC  +GGGAF IP+ I   
Sbjct: 20  ELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLV 79

Query: 84  VCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFY 143
           + GIP+ +LE A+GQ   +GS+  W  I P  +G+GLAS++    + +YY  I++W ++Y
Sbjct: 80  LEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWY 139

Query: 144 LFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGI 203
           LF+SF   LPW+ C            LN +  G V      +SPV  FW R  L I++ I
Sbjct: 140 LFNSFQEPLPWSDCP-----------LNENQTGYVDECAR-SSPVDYFWYRETLNISTSI 187

Query: 204 HDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGA 263
            D GS++W + LCL  AW + Y C  +G+++TGK VY T+T PY++L I LIRG+TL GA
Sbjct: 188 SDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGA 247

Query: 264 YQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALC 323
             GI++   P++  L  P  W+DAG Q+FFSF++  G L +  SYN  HNNC KD + + 
Sbjct: 248 TNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVS 307

Query: 324 FLNSATSFVAGFVVFSILGF---------------------------MSQEQGVPISE-- 354
            +N  TS     VV+S++GF                           ++QE  V + +  
Sbjct: 308 IINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRC 367

Query: 355 -----------------------VAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFL 391
                                   A  G GLAFI F +A+T MPLS LWS LFFIML  L
Sbjct: 368 NASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCL 427

Query: 392 GLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLF 451
           GL S F  +E +V    D+  R +     +E+L   I +  +LIG       G Y   L 
Sbjct: 428 GLSSMFGNMEGVVVPLQDL--RVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLL 485

Query: 452 DYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLA 511
           D YA S I LL ++  E+  + +VYG DRF  +IE MIG++P    +++W  ++P L L 
Sbjct: 486 DSYAGS-IPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLI 544

Query: 512 TFLFSL--------------SKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVIT 557
            FLF                  Y     +    YP W Y +   +A    + +P + +  
Sbjct: 545 IFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYK 604

Query: 558 LLK 560
           L++
Sbjct: 605 LIR 607


>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
          Length = 628

 Score =  372 bits (954), Expect = e-103
 Identities = 219/596 (36%), Positives = 318/596 (53%), Gaps = 86/596 (14%)

Query: 35  DRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEV 94
           +R +W NK +++LS  G  +GLGN+WRFPYLC   GGGAF IPY I     GIP+F +E+
Sbjct: 17  ERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIFHVEL 76

Query: 95  ALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPW 154
           A+GQ   +GSV  W  I P   G+GL  V +   +++YY  I+AW L+YL +SF   LPW
Sbjct: 77  AIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPW 136

Query: 155 TTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWELA 214
           ++C    N    T F+              +S V  FW R+ L IT+ I+D GS++W L 
Sbjct: 137 SSCPPDLNR---TGFVEECQG---------SSAVSYFWYRQTLNITADINDSGSIQWWLL 184

Query: 215 LCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPD 274
           +CL  +W + Y C+ +G+++TGKV+YFTA FPYL+L I LIRG+TLPGA +G+IY   P+
Sbjct: 185 ICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYLFTPN 244

Query: 275 LFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAG 334
           +  L++P+VW+DA TQIFFS ++  G   A  SYN   N+C KD + +  +N  TS  A 
Sbjct: 245 MHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLYAS 304

Query: 335 FVVFSILGFMS---------------------QEQGV----------------------- 350
             VFS+LGF +                      EQ +                       
Sbjct: 305 IAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQL 364

Query: 351 PIS--------EVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVEC 402
           P+         + + SGPGLAF+ F +    MP + +W+ LFF ML  LGL + F  VE 
Sbjct: 365 PLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFGTVEA 424

Query: 403 LVTASID--MFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGIC 460
           ++T  +D  + PR + K    E L   + ++C+L       + G Y  ++FD +A+S   
Sbjct: 425 VITPLLDVGVLPRWVPK----EALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASP-N 479

Query: 461 LLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFL--FSLS 518
           LL L+  EVV + +VYG  RF D+I  M G RP P  +++W  ++P L L  F+    L 
Sbjct: 480 LLMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSP-LLLTIFVAYIILL 538

Query: 519 KYTPLKY---NNVY---------VYPPWGYSIGWFLALSSMVCVPLFVVITLLKTR 562
            + PL+Y   N  Y         +YP W  +    L+L  ++ VP+  +  LL  R
Sbjct: 539 FWKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALAQLLTRR 594


>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
           sapiens]
          Length = 592

 Score =  354 bits (908), Expect = 2e-97
 Identities = 210/595 (35%), Positives = 304/595 (51%), Gaps = 81/595 (13%)

Query: 34  KDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLE 93
           K R  W N ++FV +     +GLGNVWRFPYLC   GGG+F +PY I   V G+P+ +LE
Sbjct: 3   KARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLE 62

Query: 94  VALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELP 153
           +A+GQ   QGS+ AWR I P   G+G+ASVV+  +L++YY +I AWA +YLF SF   LP
Sbjct: 63  LAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLP 122

Query: 154 WTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWEL 213
           W+ C            LN +  G     E  +S    FW R+ L I+  + + G ++WE 
Sbjct: 123 WSVCP-----------LNGNHTGYDEECEKASS-TQYFWYRKTLNISPSLQENGGVQWEP 170

Query: 214 ALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKP 273
           ALCLLLAW++ Y CI +G +STGKVVYFTA+ PY +L+I LIRG+TL GA  G++Y   P
Sbjct: 171 ALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTP 230

Query: 274 DLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVA 333
            + +L +P+ W++A TQIFFS  +  G L A  SYN+  NNC K  I +  +NS TS  A
Sbjct: 231 KIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFA 290

Query: 334 GFVVFSILGFMSQ--------------------EQGVPISEVAESGPGLAFIAFP----- 368
             V FSI GF +                     E G   +   E   G    A+P     
Sbjct: 291 SIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSE 350

Query: 369 -----------------------------KAVTMMPLSQLWSCLFFIMLIFLGLDSQFVC 399
                                        +A+  M +SQLWS L+F ML+ LG+ S    
Sbjct: 351 MFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGN 410

Query: 400 VECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGI 459
              ++T   D   + +     +E +   + ++   IG+    E G Y F +F+ YA++ +
Sbjct: 411 TAAILTPLTD--SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT-L 467

Query: 460 CLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSK 519
            LL + L E + + +VYG  RF  +++ M G       K+ W  ++P L ++ F+F LS 
Sbjct: 468 SLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSD 527

Query: 520 YT---PLKYNN---------VYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTR 562
           Y     LKY              YP +  ++   L  SS +C+PL  + T ++ R
Sbjct: 528 YILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRR 582


>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
           sapiens]
          Length = 555

 Score =  294 bits (752), Expect = 2e-79
 Identities = 189/595 (31%), Positives = 277/595 (46%), Gaps = 118/595 (19%)

Query: 34  KDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLE 93
           K R  W N ++FV +     +GLGNVWRFPYLC   GGG+F +PY I   V G+P+ +LE
Sbjct: 3   KARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLE 62

Query: 94  VALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELP 153
           +A+GQ   QGS+ AWR I P   G+G+ASVV+  +L++YY +I AWA +YLF SF   LP
Sbjct: 63  LAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLP 122

Query: 154 WTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWEL 213
           W+ C            LN +  G     E  +S    FW R+ L I+  + + G ++WE 
Sbjct: 123 WSVCP-----------LNGNHTGYDEECEKASS-TQYFWYRKTLNISPSLQENGGVQWEP 170

Query: 214 ALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKP 273
           ALCLLLAW++ Y CI +G +STGK+                                   
Sbjct: 171 ALCLLLAWLVVYLCILRGTESTGKIE---------------------------------- 196

Query: 274 DLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVA 333
              +L +P+ W++A TQIFFS  +  G L A  SYN+  NNC K  I +  +NS TS  A
Sbjct: 197 ---QLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFA 253

Query: 334 GFVVFSILGFMSQ--------------------EQGVPISEVAESGPGLAFIAFP----- 368
             V FSI GF +                     E G   +   E   G    A+P     
Sbjct: 254 SIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSE 313

Query: 369 -----------------------------KAVTMMPLSQLWSCLFFIMLIFLGLDSQFVC 399
                                        +A+  M +SQLWS L+F ML+ LG+ S    
Sbjct: 314 MFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGN 373

Query: 400 VECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGI 459
              ++T   D   + +     +E +   + ++   IG+    E G Y F +F+ YA++ +
Sbjct: 374 TAAILTPLTD--SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT-L 430

Query: 460 CLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSK 519
            LL + L E + + +VYG  RF  +++ M G       K+ W  ++P L ++ F+F LS 
Sbjct: 431 SLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSD 490

Query: 520 YT---PLKYNN---------VYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTR 562
           Y     LKY              YP +  ++   L  SS +C+PL  + T ++ R
Sbjct: 491 YILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRR 545


>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
          Length = 727

 Score =  289 bits (740), Expect = 5e-78
 Identities = 132/322 (40%), Positives = 198/322 (61%), Gaps = 10/322 (3%)

Query: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81
           G++   E+E   +DR  W +K++++L+  G  +GLGN+WRFPYLC KNGGGA+ +PY + 
Sbjct: 46  GKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVL 105

Query: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141
             + GIP+FFLE+A+GQ   +GS+  W  ICP   GIG +S ++  ++ +YY +I+ W++
Sbjct: 106 LIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSI 165

Query: 142 FYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITS 201
           FY F SF   LPW+ C            + +     V      +S    FW R  L I+ 
Sbjct: 166 FYFFKSFQYPLPWSEC----------PVVRNGSVAVVEAECEKSSATTYFWYREALDISD 215

Query: 202 GIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLP 261
            I + G L W++ LCLL+AW I    + KG++S+GKV+YF++ FPY++L   L+RG+ L 
Sbjct: 216 SISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLR 275

Query: 262 GAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIA 321
           GA  GI++   P L ++ DPQVW +A TQ+FF+  +  G + A  SYNK  NNC+ D   
Sbjct: 276 GAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAAL 335

Query: 322 LCFLNSATSFVAGFVVFSILGF 343
           + F+N  TS +A  VVF++LGF
Sbjct: 336 VSFINFFTSVLATLVVFAVLGF 357



 Score =  103 bits (256), Expect = 6e-22
 Identities = 55/153 (35%), Positives = 84/153 (54%), Gaps = 8/153 (5%)

Query: 359 GPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKS 418
           G GLAFIAF +A+T  P S  WS +FF+MLI LGL S    +  + T  ID F       
Sbjct: 437 GTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTF------K 490

Query: 419 GRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGA 478
             +E+  +   V  +L+GL  V   G Y   +FD Y S+ + L  + + E + ++W+YG 
Sbjct: 491 VPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDY-SATLPLTLIVILENIAVAWIYGT 549

Query: 479 DRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLA 511
            +F   + +M+G+RP+      W F++P LC+A
Sbjct: 550 KKFMQELTEMLGFRPYRFYFYMWKFVSP-LCMA 581


>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
           sapiens]
          Length = 730

 Score =  278 bits (712), Expect = 8e-75
 Identities = 134/325 (41%), Positives = 197/325 (60%), Gaps = 11/325 (3%)

Query: 20  EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78
           +E +  D E+  +V+D R  W +K++++L+  G  +GLGNVWRFPYLC KNGGGA+ +PY
Sbjct: 44  QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103

Query: 79  FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138
            I   V GIP+FFLE+++GQ   +GS+  W  I P   GIG AS V+  ++ +YY +I+ 
Sbjct: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163

Query: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198
           W+LFY   SF   LPW  C    N  H            V P    +S    +W R  L 
Sbjct: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213

Query: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGV 258
           I+S I + G L W++ +CLL AWV+    + KG++S+GK++YF++ FPY++L+  LIR  
Sbjct: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAF 273

Query: 259 TLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKD 318
            L G+  GI +   P L  + +P+VW +A TQ+FF+  +  G + A  SYNK  NNC+ D
Sbjct: 274 LLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFD 333

Query: 319 CIALCFLNSATSFVAGFVVFSILGF 343
            + + F+N  TS +A  VVF++LGF
Sbjct: 334 AVLVSFINFFTSVLATLVVFAVLGF 358



 Score =  117 bits (292), Expect = 4e-26
 Identities = 68/212 (32%), Positives = 113/212 (53%), Gaps = 18/212 (8%)

Query: 356 AESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQL 415
           A  G GLAFIAF +A+T  P S  WS +FF+ML+ LGL S F  +E +VT  +D F    
Sbjct: 435 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTF---- 490

Query: 416 RKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWV 475
               R+E+L +   ++ + IGL  V   G Y   +FD Y S+ + LL + + E + + +V
Sbjct: 491 --KVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDY-SATLPLLIVVILENIAVCFV 547

Query: 476 YGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSK--YTPLKYN------- 526
           YG D+F ++++DM+G+ P       W +++P + L+  + S+     +P  YN       
Sbjct: 548 YGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKA 607

Query: 527 --NVYVYPPWGYSIGWFLALSSMVCVPLFVVI 556
                 YP WG  +   L + +++ VP+  ++
Sbjct: 608 SEEFLSYPTWGLVVCVSLVVFAILPVPVVFIV 639


>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform b [Homo sapiens]
          Length = 200

 Score =  236 bits (601), Expect = 6e-62
 Identities = 107/174 (61%), Positives = 127/174 (72%), Gaps = 2/174 (1%)

Query: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

Query: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146

Query: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWE 193
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWE
Sbjct: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200


>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
           sapiens]
          Length = 623

 Score =  209 bits (532), Expect = 6e-54
 Identities = 103/260 (39%), Positives = 152/260 (58%), Gaps = 10/260 (3%)

Query: 84  VCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFY 143
           V GIP+FFLE+++GQ   +GS+  W  I P   GIG AS V+  ++ +YY +I+ W+LFY
Sbjct: 2   VIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFY 61

Query: 144 LFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGI 203
              SF   LPW  C    N  H            V P    +S    +W R  L I+S I
Sbjct: 62  FSQSFQQPLPWDQCPLVKNASHTF----------VEPECEQSSATTYYWYREALNISSSI 111

Query: 204 HDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGA 263
            + G L W++ +CLL AWV+    + KG++S+GK++YF++ FPY++L+  LIR   L G+
Sbjct: 112 SESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGS 171

Query: 264 YQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALC 323
             GI +   P L  + +P+VW +A TQ+FF+  +  G + A  SYNK  NNC+ D + + 
Sbjct: 172 IDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVS 231

Query: 324 FLNSATSFVAGFVVFSILGF 343
           F+N  TS +A  VVF++LGF
Sbjct: 232 FINFFTSVLATLVVFAVLGF 251



 Score =  117 bits (292), Expect = 4e-26
 Identities = 68/212 (32%), Positives = 113/212 (53%), Gaps = 18/212 (8%)

Query: 356 AESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQL 415
           A  G GLAFIAF +A+T  P S  WS +FF+ML+ LGL S F  +E +VT  +D F    
Sbjct: 328 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTF---- 383

Query: 416 RKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWV 475
               R+E+L +   ++ + IGL  V   G Y   +FD Y S+ + LL + + E + + +V
Sbjct: 384 --KVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDY-SATLPLLIVVILENIAVCFV 440

Query: 476 YGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSK--YTPLKYN------- 526
           YG D+F ++++DM+G+ P       W +++P + L+  + S+     +P  YN       
Sbjct: 441 YGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKA 500

Query: 527 --NVYVYPPWGYSIGWFLALSSMVCVPLFVVI 556
                 YP WG  +   L + +++ VP+  ++
Sbjct: 501 SEEFLSYPTWGLVVCVSLVVFAILPVPVVFIV 532


>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
           sapiens]
          Length = 289

 Score =  191 bits (484), Expect = 2e-48
 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%)

Query: 20  EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78
           +E +  D E+  +V+D R  W +K++++L+  G  +GLGNVWRFPYLC KNGGGA+ +PY
Sbjct: 44  QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103

Query: 79  FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138
            I   V GIP+FFLE+++GQ   +GS+  W  I P   GIG AS V+  ++ +YY +I+ 
Sbjct: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163

Query: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198
           W+LFY   SF   LPW  C    N  H            V P    +S    +W R  L 
Sbjct: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213

Query: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254
           I+S I + G L W++ +CLL AWV+    + KG++S+GKV   +   P+L+L+I +
Sbjct: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266


>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
          Length = 736

 Score =  166 bits (421), Expect = 4e-41
 Identities = 98/324 (30%), Positives = 159/324 (49%), Gaps = 12/324 (3%)

Query: 20  EEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYF 79
           E+ +  ++++ + +  R  W++K E++L+  G  +    +WRF YL   +GG +F   Y 
Sbjct: 87  EKVQMTEKKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYI 146

Query: 80  IFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAW 139
              F+ G+P+ FLE+A GQ   QG +  W+ I P   G+G +S ++   L +Y+ ++ +W
Sbjct: 147 FMLFLVGVPLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSW 206

Query: 140 ALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGI 199
            +FY+  SF   +PW         E C   +N SG     P    T+P + FW ++ L  
Sbjct: 207 IIFYMSQSFQFPVPW---------EKCPLTMNSSG---FDPECERTTPSIYFWYQQALKA 254

Query: 200 TSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVT 259
           +  I D GS  + L L   L W +    +  G+KSTGKV+Y     P  ++V   IR + 
Sbjct: 255 SDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFIRTLL 314

Query: 260 LPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDC 319
           L GA  G+   +   +  + +  VW  AG Q+  +  I  G + +L SY    NNC  D 
Sbjct: 315 LEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDA 374

Query: 320 IALCFLNSATSFVAGFVVFSILGF 343
             +  +N  T  V     F +LGF
Sbjct: 375 FLVSVINLLTLLVFTSFNFCVLGF 398


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.144    0.479 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,914,126
Number of Sequences: 37866
Number of extensions: 1118537
Number of successful extensions: 3414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3263
Number of HSP's gapped (non-prelim): 66
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.