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Search of human proteins with 17017963
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17017963 forkhead box P2 isoform I [Homo sapiens]
(715 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 1410 0.0
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 1396 0.0
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 1241 0.0
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] 843 0.0
gi|60498992 forkhead box P4 isoform 3 [Homo sapiens] 694 0.0
gi|60498989 forkhead box P4 isoform 1 [Homo sapiens] 693 0.0
gi|29789367 forkhead box P4 isoform 2 [Homo sapiens] 683 0.0
gi|167466190 forkhead box P3 isoform b [Homo sapiens] 221 2e-57
gi|31982943 forkhead box P3 isoform a [Homo sapiens] 221 2e-57
gi|221139761 zinc finger protein 853 [Homo sapiens] 126 8e-29
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 125 1e-28
gi|110347429 mediator complex subunit 12 [Homo sapiens] 121 2e-27
gi|33286444 mastermind-like 2 [Homo sapiens] 113 5e-25
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 113 7e-25
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 113 7e-25
gi|93141033 PAX interacting protein 1 [Homo sapiens] 98 2e-20
gi|226246533 TOX high mobility group box family member 3 isoform... 95 2e-19
gi|226054295 TOX high mobility group box family member 3 isoform... 95 2e-19
gi|50301236 forkhead box J1 [Homo sapiens] 91 3e-18
gi|4507379 TATA box binding protein [Homo sapiens] 88 2e-17
gi|50345831 forkhead box J3 [Homo sapiens] 88 3e-17
gi|24497506 forkhead box A3 [Homo sapiens] 87 4e-17
gi|31563338 forkhead box K2 [Homo sapiens] 83 8e-16
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 82 1e-15
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 82 1e-15
gi|4885237 forkhead box C2 [Homo sapiens] 82 2e-15
gi|148746195 trichohyalin [Homo sapiens] 82 2e-15
gi|40549454 T-cell leukemia virus enhancer factor [Homo sapiens] 81 4e-15
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens] 80 7e-15
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens] 80 7e-15
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 1410 bits (3650), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA
Sbjct: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
Query: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQA 120
ARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQA
Sbjct: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQA 120
Query: 121 LLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 180
LLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 121 LLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 180
Query: 181 QQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQG 240
QQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQG
Sbjct: 181 QQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQG 240
Query: 241 LISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTT 300
LISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTT
Sbjct: 241 LISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTT 300
Query: 301 SSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDF 360
SSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDF
Sbjct: 301 SSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDF 360
Query: 361 GQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSP 420
GQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSP
Sbjct: 361 GQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSP 420
Query: 421 KPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHS 480
KPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHS
Sbjct: 421 KPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHS 480
Query: 481 DKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAY 540
DKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAY
Sbjct: 481 DKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAY 540
Query: 541 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPT 600
FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPT
Sbjct: 541 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPT 600
Query: 601 SLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSP 660
SLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSP
Sbjct: 601 SLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSP 660
Query: 661 GCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE 715
GCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
Sbjct: 661 GCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE 715
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 1396 bits (3614), Expect = 0.0
Identities = 715/740 (96%), Positives = 715/740 (96%), Gaps = 25/740 (3%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA
Sbjct: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
Query: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQ-------------------------VPVSVAMMT 95
ARQLLLQQQTSGLKSPKSSDKQRPLQ VPVSVAMMT
Sbjct: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMT 120
Query: 96 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155
PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ
Sbjct: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
Query: 156 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL
Sbjct: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
Query: 216 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 275
VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG
Sbjct: 241 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 300
Query: 276 VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE 335
VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE
Sbjct: 301 VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE 360
Query: 336 TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL 395
TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL
Sbjct: 361 TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL 420
Query: 396 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 455
SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT
Sbjct: 421 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 480
Query: 456 PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ 515
PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ
Sbjct: 481 PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ 540
Query: 516 AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV 575
AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV
Sbjct: 541 AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV 600
Query: 576 DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS 635
DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS
Sbjct: 601 DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS 660
Query: 636 GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH 695
GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH
Sbjct: 661 GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH 720
Query: 696 SPELEDDREIEEEPLSEDLE 715
SPELEDDREIEEEPLSEDLE
Sbjct: 721 SPELEDDREIEEEPLSEDLE 740
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 1241 bits (3210), Expect = 0.0
Identities = 623/623 (100%), Positives = 623/623 (100%)
Query: 93 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 152
MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ
Sbjct: 1 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 60
Query: 153 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Query: 213 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 272
QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE
Sbjct: 121 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 180
Query: 273 VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSS 332
VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSS
Sbjct: 181 VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSS 240
Query: 333 HEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLE 392
HEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLE
Sbjct: 241 HEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLE 300
Query: 393 IQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA 452
IQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA
Sbjct: 301 IQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA 360
Query: 453 PVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL 512
PVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL
Sbjct: 361 PVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL 420
Query: 513 IRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAV 572
IRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAV
Sbjct: 421 IRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAV 480
Query: 573 WTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINN 632
WTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINN
Sbjct: 481 WTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINN 540
Query: 633 ASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT 692
ASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT
Sbjct: 541 ASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT 600
Query: 693 ANHSPELEDDREIEEEPLSEDLE 715
ANHSPELEDDREIEEEPLSEDLE
Sbjct: 601 ANHSPELEDDREIEEEPLSEDLE 623
Score = 31.2 bits (69), Expect = 3.5
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
QQQQ AA+QL+ QQQ ++ + LQ +++ Q P Q L Q
Sbjct: 112 QQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQS---LPQAG 168
Query: 113 LSPQQLQALLQQQQAV 128
LSP ++Q L ++ V
Sbjct: 169 LSPAEIQQLWKEVTGV 184
>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
Length = 677
Score = 843 bits (2177), Expect = 0.0
Identities = 453/726 (62%), Positives = 541/726 (74%), Gaps = 60/726 (8%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS-RDGRSSGDTSS-EVSTVELLHLQQQQ-- 56
MMQES TET SN S QNG + L+ G R+GRS+G+T + ++ +L H QQQQ
Sbjct: 1 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ 60
Query: 57 ALQAARQLLLQQQ----TSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
ALQ ARQLLLQQQ SGLKSPK +DKQ LQVPVSVAMMTPQVITPQQMQQILQQQV
Sbjct: 61 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV 120
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
LSPQQLQ LL QQQQ QQQQ
Sbjct: 121 LSPQQLQVLL-------------------------------------QQQQALMLQQQQL 143
Query: 173 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQH 232
Q+ ++QQ+Q Q Q QQQH GKQ KEQQQ +A QQL FQQQLLQMQQLQQQ H
Sbjct: 144 QEFYKKQQEQLQLQLLQQQHAGKQPKEQQQ-------VATQQLAFQQQLLQMQQLQQQ-H 195
Query: 233 LLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDL 291
LLSLQRQGL++I PGQ ALP+Q L Q G+ P E+QQLWKEVT H+ E+ G H LDL
Sbjct: 196 LLSLQRQGLLTIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDL 254
Query: 292 TTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWP 351
TT SS+ S TS P H+ NGQ SV + +R+S SHEE SH LYGHGVCKWP
Sbjct: 255 TTTCVSSSAPSKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWP 311
Query: 352 GCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM 411
GCE++CEDF FLKHLN+EHALDDRSTAQCRVQMQVVQQLE+QL+K++ERLQAMMTHLH+
Sbjct: 312 GCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHV 371
Query: 412 RPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPN 471
+ +EPK +P+PLNLVSSVT+SK+ E SPQSLP TPTTPTAP+TP+TQGPSVIT S+
Sbjct: 372 KSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHT 431
Query: 472 VGAIRRRHSDKYNIPMSS-EIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEI 530
VG IRRR+SDKYN+P+SS +IA N EFYKNA+VRPPFTYA+LIRQAI+ES ++QLTLNEI
Sbjct: 432 VGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEI 491
Query: 531 YSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITG 590
Y+WFTR FAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE+QKRR QKI+G
Sbjct: 492 YNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISG 551
Query: 591 SPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLD 650
+P+L+KN+ +S Y LNA+LQA++AE+S+PL + + N L A+ E+LNG+++
Sbjct: 552 NPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME 611
Query: 651 HIDSN-GNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEP 709
H +SN +SSPG SP +H +HVKEEP+ E+ + P+SLVTTANHSP+ + DR+ E+EP
Sbjct: 612 HTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEP 671
Query: 710 LSEDLE 715
++ED+E
Sbjct: 672 VNEDME 677
>gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]
Length = 678
Score = 694 bits (1790), Expect = 0.0
Identities = 397/738 (53%), Positives = 492/738 (66%), Gaps = 85/738 (11%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS------------RDGRSSGDTSSEVSTVE 48
MM ESA+ETI ++ QNG+ +LS Q D S R+ + D++ E+S E
Sbjct: 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRP---LQVPVSVAMMTPQVITPQQMQ 105
LLH QQQQALQ ARQ LLQQ SGL SP ++D ++ +QVPVSVAMM+PQ++T
Sbjct: 61 LLHFQQQQALQVARQFLLQQ-ASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLT----- 114
Query: 106 QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
PQQ+Q +L Q LQ L QQQQ QQ+
Sbjct: 115 ---------PQQMQQILSPPQ---------------------LQALLQQQQALMLQQEYY 144
Query: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
++QQ+Q Q QQQ GK Q ++ L +QL FQQQLLQMQ
Sbjct: 145 KKQQEQLHLQLLTQQQA-----------GKP--------QPKEALGNKQLAFQQQLLQMQ 185
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIK 285
QLQQQ HLL+LQRQGL+S+ P QA+ P+Q+LPQA + P ++ QLWK ++ +K
Sbjct: 186 QLQQQ-HLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQPAEDSVK 244
Query: 286 HGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGH 345
GLDLT +++T+ + K SPP++HH++ NGQ +VL++RRDSSSHEET SH LYGH
Sbjct: 245 QEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGSHPLYGH 304
Query: 346 GVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAM 405
G CKWPGCE++CED GQF+KHLN EHALDDRSTAQCRVQMQVVQQLEIQL+KE ERLQAM
Sbjct: 305 GECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAM 364
Query: 406 MTHLHMRPSEPKPSPKPLNLV------SSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQ 459
M HLHMRPSEPKP +PLN V S VT+S ++ P L PT+ APVTP+
Sbjct: 365 MAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVS--AADSFPDGLVHPPTSAAAPVTPLR- 421
Query: 460 GPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIME 519
P + AS+ G RRR SDK+ P+SSE+A N+EFYKNADVRPPFTYA+LIRQAI+E
Sbjct: 422 -PPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILE 480
Query: 520 SSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE 579
+ DRQLTLNEIY+WFTR FAYFRRN ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE E
Sbjct: 481 TPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDERE 540
Query: 580 YQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLIN-NASSGLL 638
YQKRR K+TGSPTLVKN+ + L YG ALNAS QAALAESS PLL++PG++N ++S LL
Sbjct: 541 YQKRRPPKMTGSPTLVKNMISGLSYG-ALNASYQAALAESSFPLLNSPGMLNPGSASSLL 599
Query: 639 QAVHEDLNGSLDHIDSNGNSS-PGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSP 697
H+D+ ++ + SNG+SS P SP + H + VKEEP AE++ P + N S
Sbjct: 600 PLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSA 659
Query: 698 E-LEDDREIEEEPLSEDL 714
+DR++EEE E+L
Sbjct: 660 SGPPEDRDLEEELPGEEL 677
>gi|60498989 forkhead box P4 isoform 1 [Homo sapiens]
Length = 680
Score = 693 bits (1789), Expect = 0.0
Identities = 397/738 (53%), Positives = 490/738 (66%), Gaps = 83/738 (11%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS------------RDGRSSGDTSSEVSTVE 48
MM ESA+ETI ++ QNG+ +LS Q D S R+ + D++ E+S E
Sbjct: 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRP---LQVPVSVAMMTPQVITPQQMQ 105
LLH QQQQALQ ARQ LLQQ SGL SP ++D ++ +QVPVSVAMM+PQ+
Sbjct: 61 LLHFQQQQALQVARQFLLQQ-ASGLSSPGNNDSKQSASAVQVPVSVAMMSPQM------- 112
Query: 106 QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
L+PQQ+Q Q+L Q Q QQQQ
Sbjct: 113 -------LTPQQMQ-----------------------------QILSPPQLQALLQQQQA 136
Query: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
QQ Q+ ++QQ+Q Q QQQ Q KE L +QL FQQQLLQMQ
Sbjct: 137 LMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEA---------LGNKQLAFQQQLLQMQ 187
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIK 285
QLQQQ HLL+LQRQGL+S+ P QA+ P+Q+LPQA + P ++ QLWK ++ +K
Sbjct: 188 QLQQQ-HLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQPAEDSVK 246
Query: 286 HGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGH 345
GLDLT +++T+ + K SPP++HH++ NGQ +VL++RRDSSSHEET SH LYGH
Sbjct: 247 QEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGSHPLYGH 306
Query: 346 GVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAM 405
G CKWPGCE++CED GQF+KHLN EHALDDRSTAQCRVQMQVVQQLEIQL+KE ERLQAM
Sbjct: 307 GECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAM 366
Query: 406 MTHLHMRPSEPKPSPKPLNLV------SSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQ 459
M HLHMRPSEPKP +PLN V S VT+S ++ P L PT+ APVTP+
Sbjct: 367 MAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVS--AADSFPDGLVHPPTSAAAPVTPLR- 423
Query: 460 GPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIME 519
P + AS+ G RRR SDK+ P+SSE+A N+EFYKNADVRPPFTYA+LIRQAI+E
Sbjct: 424 -PPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILE 482
Query: 520 SSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE 579
+ DRQLTLNEIY+WFTR FAYFRRN ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE E
Sbjct: 483 TPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDERE 542
Query: 580 YQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLIN-NASSGLL 638
YQKRR K+TGSPTLVKN+ + L YG ALNAS QAALAESS PLL++PG++N ++S LL
Sbjct: 543 YQKRRPPKMTGSPTLVKNMISGLSYG-ALNASYQAALAESSFPLLNSPGMLNPGSASSLL 601
Query: 639 QAVHEDLNGSLDHIDSNGNSS-PGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSP 697
H+D+ ++ + SNG+SS P SP + H + VKEEP AE++ P + N S
Sbjct: 602 PLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSA 661
Query: 698 E-LEDDREIEEEPLSEDL 714
+DR++EEE E+L
Sbjct: 662 SGPPEDRDLEEELPGEEL 679
>gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]
Length = 667
Score = 683 bits (1763), Expect = 0.0
Identities = 390/732 (53%), Positives = 486/732 (66%), Gaps = 84/732 (11%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS------------RDGRSSGDTSSEVSTVE 48
MM ESA+ETI ++ QNG+ +LS Q D S R+ + D++ E+S E
Sbjct: 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRP---LQVPVSVAMMTPQVITPQQMQ 105
LLH QQQQALQ ARQ LLQQ SGL SP ++D ++ +QVPVSVAMM+PQ+
Sbjct: 61 LLHFQQQQALQVARQFLLQQ-ASGLSSPGNNDSKQSASAVQVPVSVAMMSPQM------- 112
Query: 106 QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
L+PQQ+Q Q+L Q Q QQQQ
Sbjct: 113 -------LTPQQMQ-----------------------------QILSPPQLQALLQQQQA 136
Query: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
QQ Q+ ++QQ+Q Q QQQ Q KE L +QL FQQQLLQMQ
Sbjct: 137 LMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEA---------LGNKQLAFQQQLLQMQ 187
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIK 285
QLQQQ HLL+LQRQGL+S+ P QA+ P+Q+LPQA + P ++ QLWK ++ +K
Sbjct: 188 QLQQQ-HLLNLQRQGLVSLQPNQASGPLQTLPQA-VCPTDLPQLWKGEGAPGQPAEDSVK 245
Query: 286 HGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGH 345
GLDLT +++T+ + K SPP++HH++ NGQ +VL++RRDSSSHEET SH LYGH
Sbjct: 246 QEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGSHPLYGH 305
Query: 346 GVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAM 405
G CKWPGCE++CED GQF+KHLN EHALDDRSTAQCRVQMQVVQQLEIQL+KE ERLQAM
Sbjct: 306 GECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAM 365
Query: 406 MTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVIT 465
M HLHMRPSEPKP +P+ + ++ ++ P L PT+ APVTP+ P +
Sbjct: 366 MAHLHMRPSEPKPFSQPVTVSAA--------DSFPDGLVHPPTSAAAPVTPLR--PPGLG 415
Query: 466 PASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQL 525
AS+ G RRR SDK+ P+SSE+A N+EFYKNADVRPPFTYA+LIRQAI+E+ DRQL
Sbjct: 416 SASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQL 475
Query: 526 TLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRS 585
TLNEIY+WFTR FAYFRRN ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE EYQKRR
Sbjct: 476 TLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRP 535
Query: 586 QKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLIN-NASSGLLQAVHED 644
K+TGSPTLVKN+ + L YG ALNAS QAALAESS PLL++PG++N ++S LL H+D
Sbjct: 536 PKMTGSPTLVKNMISGLSYG-ALNASYQAALAESSFPLLNSPGMLNPGSASSLLPLSHDD 594
Query: 645 LNGSLDHIDSNGNSS-PGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPE-LEDD 702
+ ++ + SNG+SS P SP + H + VKEEP AE++ P + N S +D
Sbjct: 595 VGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSASGPPED 654
Query: 703 REIEEEPLSEDL 714
R++EEE E+L
Sbjct: 655 RDLEEELPGEEL 666
>gi|167466190 forkhead box P3 isoform b [Homo sapiens]
Length = 396
Score = 221 bits (563), Expect = 2e-57
Identities = 119/261 (45%), Positives = 163/261 (62%), Gaps = 18/261 (6%)
Query: 327 RRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQ 386
R+DS+ +S+ L +GVCKWPGCE + E+ FLKH +H LD++ AQC +Q +
Sbjct: 143 RKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQRE 202
Query: 387 VVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQT 446
+VQ LE QL E+E+L AM HL + + K S ++ SS S ++ Q
Sbjct: 203 MVQSLEQQLVLEKEKLSAMQAHLAGKMALTKAS----SVASSDKGSCCIVAAGSQG---- 254
Query: 447 PTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPP 506
PV P GP + ++ A+RR + E N +++K ++RPP
Sbjct: 255 ------PVVPAWSGPR----EAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPP 304
Query: 507 FTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVE 566
FTYATLIR AI+E+ ++Q TLNEIY WFTR FA+FR + ATWKNA+RHNLSLHKCFVRVE
Sbjct: 305 FTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVE 364
Query: 567 NVKGAVWTVDEVEYQKRRSQK 587
+ KGAVWTVDE+E++K+RSQ+
Sbjct: 365 SEKGAVWTVDELEFRKKRSQR 385
>gi|31982943 forkhead box P3 isoform a [Homo sapiens]
Length = 431
Score = 221 bits (563), Expect = 2e-57
Identities = 119/261 (45%), Positives = 163/261 (62%), Gaps = 18/261 (6%)
Query: 327 RRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQ 386
R+DS+ +S+ L +GVCKWPGCE + E+ FLKH +H LD++ AQC +Q +
Sbjct: 178 RKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQRE 237
Query: 387 VVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQT 446
+VQ LE QL E+E+L AM HL + + K S ++ SS S ++ Q
Sbjct: 238 MVQSLEQQLVLEKEKLSAMQAHLAGKMALTKAS----SVASSDKGSCCIVAAGSQG---- 289
Query: 447 PTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPP 506
PV P GP + ++ A+RR + E N +++K ++RPP
Sbjct: 290 ------PVVPAWSGPR----EAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPP 339
Query: 507 FTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVE 566
FTYATLIR AI+E+ ++Q TLNEIY WFTR FA+FR + ATWKNA+RHNLSLHKCFVRVE
Sbjct: 340 FTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVE 399
Query: 567 NVKGAVWTVDEVEYQKRRSQK 587
+ KGAVWTVDE+E++K+RSQ+
Sbjct: 400 SEKGAVWTVDELEFRKKRSQR 420
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 126 bits (316), Expect = 8e-29
Identities = 94/231 (40%), Positives = 121/231 (52%), Gaps = 15/231 (6%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
Q +Q Q L LQQQ + S Q+ V + P++ Q QQ+ QQV
Sbjct: 105 QHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV 164
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
Q+LQ +Q Q Q+QQ+ + ++ Q+Q+ Q L QQQQ+Q QQQQ QQQ+Q Q
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQ 224
Query: 173 QQQQQQQQQQQQQQQ-----QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL--QMQ 225
QQQ QQQQ+Q QQQQ QQQ +Q +QQQ Q QQQ L QQ QQQLL Q +
Sbjct: 225 QQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQE 284
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGV 276
QLQQQQ LQ+Q Q L Q L L P E +++ E+ V
Sbjct: 285 QLQQQQQQQLLQQQ--------QEQLQQQQLQPPPLEPEEEEEVELELMPV 327
Score = 125 bits (315), Expect = 1e-28
Identities = 93/235 (39%), Positives = 124/235 (52%), Gaps = 5/235 (2%)
Query: 51 HLQ-QQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQ 109
HL+ QQQ Q +Q L Q Q +S + + LQ+ + PQ + QQ Q Q
Sbjct: 115 HLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQ 174
Query: 110 QQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQ 169
+Q+ + Q + + QQQ + QQ Q Q+ ++QQEQL Q L QQQ+Q QQQQ QQQQ+Q
Sbjct: 175 EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQ 234
Query: 170 QQQQQQ----QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
QQQQQ QQQ Q QQQ QQQQ +Q EQQQ Q QQQ L QQ QQQ Q
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSME 280
QQQ+ L Q Q P + + ++ +P S E++Q +E+ +E
Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELE 349
Score = 116 bits (290), Expect = 8e-26
Identities = 106/392 (27%), Positives = 167/392 (42%), Gaps = 35/392 (8%)
Query: 79 SDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEF 138
+++ RP Q + + + Q P+ QQ +Q+ PQ L QQ Q QQQL +
Sbjct: 79 AEETRPGQRELQLQQLEQQ---PEPQQQPQHEQLQQPQPHLELQQQPQQD--GQQQLSQL 133
Query: 139 YKKQQEQLHLQLLQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQH 192
+++ + +H Q L+ QQQQ Q QQ Q+QQ+ QQQQ+Q Q QQ Q+QQ QQQ+
Sbjct: 134 QQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQ 193
Query: 193 PGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALP 252
+Q +EQQ QQQQ+QL QQL+ QQ+ LQ QQ QQQQ L Q+Q L+ GQ
Sbjct: 194 LQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQ 253
Query: 253 VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPIT 312
+ QA L ++Q ++ ++ PP+
Sbjct: 254 LLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLE 313
Query: 313 HHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHA 372
+ ++ D S +E E Q L+
Sbjct: 314 PEEEEEVELELMPV--DLGSEQE---------------------LEQQRQELERQQELER 350
Query: 373 LDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMS 432
++ Q ++Q + +QQLE QL +++++L+ L + P E + + L +
Sbjct: 351 QQEQRQLQLKLQ-EELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQP 409
Query: 433 KNMLETSPQSLPQTPTTPTAPVTPITQGPSVI 464
+ LE P + P AP + P +
Sbjct: 410 ELQLELVPAAGGGGAAVPGAPAAVVVAPPGYV 441
Score = 110 bits (275), Expect = 5e-24
Identities = 93/254 (36%), Positives = 129/254 (50%), Gaps = 36/254 (14%)
Query: 47 VELLHLQQQ-QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQ 105
++L+H QQQ Q Q Q LQQQ L++ ++ ++Q V Q+ Q Q
Sbjct: 150 LQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ--------VLQQQEQLQQQVQEQ 201
Query: 106 QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
Q+LQQQ QQ Q L QQ+Q LQQQQ Q+ ++ Q+Q L LLQQQ Q QQQ QQQ
Sbjct: 202 QLLQQQQEQLQQQQLLQQQEQ---LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQ 258
Query: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV--------- 216
Q Q QQQ +QQQ Q QQQ QQQ+ +Q ++QQ QQQQ+QL QQL
Sbjct: 259 QAQLQQQLLEQQQAQLQQQLLLQQQEQL-QQQQQQQLLQQQQEQLQQQQLQPPPLEPEEE 317
Query: 217 -------------FQQQL-LQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262
+Q+L Q Q+L++QQ L Q Q + + + ++ +
Sbjct: 318 EEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQ 377
Query: 263 PAEIQQLWKEVTGV 276
E Q++ E+T V
Sbjct: 378 QLEQQEVQLELTPV 391
Score = 97.1 bits (240), Expect = 5e-20
Identities = 75/217 (34%), Positives = 121/217 (55%), Gaps = 27/217 (12%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
QQQ+ LQ +QLLL QQ L+ +Q LQ Q++ QQ Q LQQQ+
Sbjct: 230 QQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQ---------QQLLEQQQAQ--LQQQL 278
Query: 113 LSPQQLQALLQQQQAVM------LQQQQLQ--EFYKKQQEQLHLQL----LQQQQQQQQQ 160
L QQ Q QQQQ ++ LQQQQLQ +++E++ L+L L +Q+ +QQ
Sbjct: 279 LLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQ 338
Query: 161 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQ 220
+Q+ ++QQ+ ++QQ+Q+Q Q + Q++ QQ + +Q ++Q +QQ+ Q +L +L QQQ
Sbjct: 339 RQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQ 398
Query: 221 LLQMQ----QLQQQQHLLSLQRQGLISIPPGQAALPV 253
+Q++ Q + Q L+ G ++P AA+ V
Sbjct: 399 EVQLELTPVQPELQLELVPAAGGGGAAVPGAPAAVVV 435
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/267 (18%), Positives = 99/267 (37%), Gaps = 24/267 (8%)
Query: 171 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ---QQLLQMQQL 227
+ Q++++ Q++ Q+ P ++ ++ + Q++L QQL Q QQ Q +QL
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQL 109
Query: 228 QQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHS--------- 278
QQ Q L LQ+Q P + L Q Q+L E+ +H
Sbjct: 110 QQPQPHLELQQQ-----PQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV 164
Query: 279 MEDNGIKHGGLDLTTNNS-SSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETG 337
E ++ L T + + + ++ Q L ++ E+
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQ 224
Query: 338 ASHTLYGHGVCKWPGCESICEDFGQFLKHL------NNEHALDDRSTAQCRVQMQVVQQL 391
+ + + GQ + L + L ++ AQ + Q+ + QQ
Sbjct: 225 QQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQE 284
Query: 392 EIQLSKERERLQAMMTHLHMRPSEPKP 418
++Q ++++ LQ L + +P P
Sbjct: 285 QLQQQQQQQLLQQQQEQLQQQQLQPPP 311
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 20/95 (21%)
Query: 152 QQQQQQQQQQQQQQQQQ---------QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 202
+ Q++++ Q++ Q+ + ++ + Q++ Q QQ +QQ P QQQ
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEP------QQQ 103
Query: 203 QQQQQQQLAAQQLVFQQQ-----LLQMQQLQQQQH 232
Q +Q Q L QQQ Q+ QLQQ++H
Sbjct: 104 PQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKH 138
Score = 34.7 bits (78), Expect = 0.32
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 159 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQQQQLAAQ 213
+ Q++++ Q++ Q+ + ++ PG+ Q EQQ + QQQ Q +
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQ--HE 107
Query: 214 QLVFQQQLLQMQQLQQ---QQHLLSLQRQGLISIPPGQAALPVQSL-PQAGLSPAEIQQ 268
QL Q L++QQ Q QQ L LQ++ S+ + +Q + Q L P ++Q+
Sbjct: 108 QLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQE 166
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 125 bits (315), Expect = 1e-28
Identities = 95/219 (43%), Positives = 120/219 (54%), Gaps = 17/219 (7%)
Query: 55 QQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLS 114
Q L A+ +LQQQ G P+ +Q + + S + +PQ+ QQ Q ++ ++++
Sbjct: 3799 QGMLGPAQVAVLQQQHPGALGPQGPHRQ--VLMTQSRVLSSPQLA--QQGQGLMGHRLVT 3854
Query: 115 PQQLQALLQ-QQQAVMLQQQQLQEFYKKQQEQLHL---------QLLQQQQQQQQQQ-QQ 163
QQ Q Q QQQ M LQ+ Q L QL QQQQ QQQQQ QQ
Sbjct: 3855 AQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQ 3914
Query: 164 QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQ 223
QQQQQ QQQQQ QQQQ QQQQQQQQ QQ +Q ++QQQQ QQQQQ QQ QQQ Q
Sbjct: 3915 QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQ 3974
Query: 224 MQQLQQQQHLLS--LQRQGLISIPPGQAALPVQSLPQAG 260
M L Q + LLS Q+Q +++ PG A P+Q G
Sbjct: 3975 MGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG 4013
Score = 85.9 bits (211), Expect = 1e-16
Identities = 72/195 (36%), Positives = 92/195 (47%), Gaps = 19/195 (9%)
Query: 7 TETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLL 66
+ +S+ + Q G + +L + + + S L HLQQ + + L
Sbjct: 3832 SRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQ-QHQQQGSMAGLSHLQQSLMSHSGQPKLS 3890
Query: 67 QQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQ 126
Q L+ + +Q+ LQ Q + QQ QQ+ QQQ L QQLQ QQQQ
Sbjct: 3891 AQPMGSLQQLQ---QQQQLQ--------QQQQLQQQQQQQLQQQQQLQQQQLQ---QQQQ 3936
Query: 127 AVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 186
LQQQQ Q+ QQ+Q LQ QQQQQQ Q QQQQQQQQ Q + QQQQQ
Sbjct: 3937 QQQLQQQQQQQL---QQQQQQLQQQQQQQQQ-QFQQQQQQQQMGLLNQSRTLLSPQQQQQ 3992
Query: 187 QQQQQHPGKQAKEQQ 201
QQ PG AK Q
Sbjct: 3993 QQVALGPGMPAKPLQ 4007
Score = 60.1 bits (144), Expect = 7e-09
Identities = 76/330 (23%), Positives = 124/330 (37%), Gaps = 58/330 (17%)
Query: 149 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQHPGKQAKEQQQQQQ 205
+LLQ++Q Q QQQ+ Q Q+ QQQQQQQQQQQ Q QQQQQQ PG Q + +
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773
Query: 206 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 265
Q + Q L +QQL Q P G PQ L PA+
Sbjct: 3774 QGLMPPS-----SHQGLLVQQLSPQP-------------PQG---------PQGMLGPAQ 3806
Query: 266 IQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLS 325
+ L ++ G G + + S +S ++ + H +V Q
Sbjct: 3807 VAVLQQQHPGA-----LGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQ---- 3857
Query: 326 ARRDSSSHEETGASHTL--YGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRV 383
++ H++ G+ L + G + L+ L + L + Q +
Sbjct: 3858 -QQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQ 3916
Query: 384 QMQVVQQLEIQ-------------LSKERERLQAMMTHLHMRPSEPK---PSPKPLNLVS 427
Q Q+ QQ ++Q +++++LQ L + + + + +
Sbjct: 3917 QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976
Query: 428 SVTMSKNMLETSPQSLPQTPTTPTAPVTPI 457
+ S+ +L Q Q P P P+
Sbjct: 3977 LLNQSRTLLSPQQQQQQQVALGPGMPAKPL 4006
Score = 59.7 bits (143), Expect = 9e-09
Identities = 53/158 (33%), Positives = 79/158 (50%), Gaps = 16/158 (10%)
Query: 105 QQILQQQV-LSPQQLQALLQQQQAVMLQQQQLQ----EFYKKQQEQLHLQLLQQQQQQQQ 159
QQ+LQ Q+ + +Q+ + ++A+ +Q+ + EF + E+L L QQ + Q+Q
Sbjct: 3518 QQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQ 3577
Query: 160 QQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216
Q ++QQ++ + + +QQQQQQQQQQQQQQH A Q + +L
Sbjct: 3578 LDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPG---- 3633
Query: 217 FQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQ 254
QLL LQ Q Q GL + PG ALP Q
Sbjct: 3634 ---QLLPGHGLQPPQGPPGGQAGGL-RLTPGGMALPGQ 3667
Score = 55.8 bits (133), Expect = 1e-07
Identities = 67/235 (28%), Positives = 84/235 (35%), Gaps = 78/235 (33%)
Query: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ----------------- 158
Q+ Q LQQQ+ + Q+ Q Q+ ++QQ+ L Q+ QQQQQQ
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGL 3776
Query: 159 ----QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK------------------- 195
Q QQ Q Q Q Q QQQHPG
Sbjct: 3777 MPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLS 3836
Query: 196 -----------------QAKEQQQQQQQQQQ---------------------LAAQQLVF 217
A++QQQQQQ QQQ L+AQ +
Sbjct: 3837 SPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGS 3896
Query: 218 QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 272
QQL Q QQLQQQQ L Q+Q L Q Q Q L + QQL ++
Sbjct: 3897 LQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951
Score = 51.6 bits (122), Expect = 3e-06
Identities = 41/135 (30%), Positives = 51/135 (37%), Gaps = 1/135 (0%)
Query: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 189
L + + +E KKQQ LQ QQQQQQQQQ Q + QQ
Sbjct: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ 3311
Query: 190 QQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL-QMQQLQQQQHLLSLQRQGLISIPPGQ 248
Q G Q Q QQ+L M + Q H+LS Q G + P Q
Sbjct: 3312 QLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQ 3371
Query: 249 AALPVQSLPQAGLSP 263
++ PV S G P
Sbjct: 3372 SSQPVLSQKPMGTMP 3386
Score = 47.0 bits (110), Expect = 6e-05
Identities = 42/153 (27%), Positives = 75/153 (49%), Gaps = 29/153 (18%)
Query: 121 LLQQQQAVMLQQQQLQE---FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ 177
L QQ + +Q + L+E ++K ++ L + ++ ++ + ++ + +QQ +
Sbjct: 3514 LFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSK 3573
Query: 178 QQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 237
Q+Q Q ++QQ++H A+ + +QQQQQQQ QQQ Q QQQH
Sbjct: 3574 IQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQ--------QQQ--Q-----QQQH----- 3613
Query: 238 RQGLISIPPGQA-----ALPVQSLPQAGLSPAE 265
++++ P Q+ LP Q LP GL P +
Sbjct: 3614 -SAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQ 3645
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Query: 30 GSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPV 89
G G+ +SSE S+V HL Q ++ Q T L P+ +RP+Q
Sbjct: 4113 GGSHGQLGSGSSSEASSVP--HLLAQPSVSLGDQP--GSMTQNLLGPQQPMLERPMQNNT 4168
Query: 90 SVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 149
P + Q Q L + P Q L Q Q V+ + QL+ +QQ+QL
Sbjct: 4169 GPQPPKPGPVL--QSGQGLPGVGIMPTVGQ-LRAQLQGVLAKNPQLRHLSPQQQQQLQAL 4225
Query: 150 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
L+Q+Q QQ Q +Q Q+ Q Q
Sbjct: 4226 LMQRQLQQSQAVRQTPPYQEPGTQTSPLQ 4254
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 413 PSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNV 472
P E SP P L S + ++ L P+ P +P ++P +P+ + P + P P
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP-LSPPEESPPS 529
Query: 473 GAIRRRHSDKYNIPMSSEIAPNYE 496
A+ S P +S ++P +E
Sbjct: 530 PALETPLSPP---PEASPLSPPFE 550
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 121 bits (304), Expect = 2e-27
Identities = 81/180 (45%), Positives = 106/180 (58%), Gaps = 8/180 (4%)
Query: 51 HLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQ 110
HLQQ+ + +Q GL S + Q Q P+ ++ MTP ++ Q +Q ++
Sbjct: 1990 HLQQRPSGYVHQQA--PTYGHGLTSTQRFSHQTLQQTPM-ISTMTP--MSAQGVQAGVRS 2044
Query: 111 QVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 170
+ P+Q Q QQQQ QQQQ Q+ ++QQ+Q H++ QQQQ +QQQQQQQQQQQQ
Sbjct: 2045 TAILPEQQQ---QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ 2101
Query: 171 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQ 230
QQQQQQQQQQQQQQ QQQQQQ + Q Q Q Q+Q Q QQ ++QLQQQ
Sbjct: 2102 QQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQ 2161
Score = 110 bits (274), Expect = 6e-24
Identities = 75/151 (49%), Positives = 89/151 (58%), Gaps = 14/151 (9%)
Query: 100 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 159
T QQ I +S Q +QA ++ + QQQQ Q+ ++QQ+Q Q QQQQQ
Sbjct: 2020 TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
Query: 160 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA------- 212
+QQQQQQ +QQQQQQQQQQQQQQQQQQQQQQ +QQQ QQQQQQ AA
Sbjct: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ-------QQQQHQQQQQQQAAPPQPQPQ 2132
Query: 213 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS 243
Q FQ+Q LQ Q QQQ L Q Q +S
Sbjct: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
Score = 93.2 bits (230), Expect = 8e-19
Identities = 88/261 (33%), Positives = 110/261 (42%), Gaps = 50/261 (19%)
Query: 50 LHLQQQQALQAARQLLLQ-QQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQIL 108
++ QQQ A+ ++L Q QQ+ G+ S + P S + T Q TP L
Sbjct: 1897 VYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSS---SYGLQTSQGYTPYVSHVGL 1953
Query: 109 QQQV----------LSPQQLQALLQQQQAVMLQQ----QQLQEFYKKQQEQLHLQLLQQQ 154
QQ S Q Q+ ++ QQ Y QQ + L
Sbjct: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
Query: 155 QQQQQQQQQQ---------------------------QQQQQQQQQQQQQQQQQQQQQQQ 187
Q+ Q QQ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
Query: 188 QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG 247
QQQ H +Q ++Q +QQQQQQ QQ QQQ Q QQ QQQQH Q+Q + PP
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQ--QQQQQQQQQQQQQQHQQQQQQQ---AAPPQ 2128
Query: 248 QAALPVQSLPQAGLSPAEIQQ 268
+ GL + QQ
Sbjct: 2129 PQPQSQPQFQRQGLQQTQQQQ 2149
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/158 (39%), Positives = 77/158 (48%), Gaps = 10/158 (6%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
LQQ + + Q +G++S +Q+ Q Q QQ QQ QQQ
Sbjct: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQ----------QQQQQQQQQQQQQQQ 2070
Query: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
QQ QQQQ ++ QQQQ Q+ ++QQ+Q Q QQQQQ QQQQQQQ Q Q
Sbjct: 2071 QQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130
Query: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 209
Q Q Q Q+Q QQ QQQQQ + QQQ Q Q
Sbjct: 2131 PQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Score = 53.5 bits (127), Expect = 7e-07
Identities = 52/173 (30%), Positives = 72/173 (41%), Gaps = 15/173 (8%)
Query: 5 SATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQL 64
++T+ S+ ++ Q M + + + A G +G S+ + + QQQQ Q +Q
Sbjct: 2011 TSTQRFSHQTLQQTPMISTMTPMSA---QGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQ 2067
Query: 65 LLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQ 124
QQQ + +Q+ L+ Q QQ QQ QQQ Q QQ
Sbjct: 2068 QQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQ------QQ 2121
Query: 125 QQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ 177
QQA Q Q + Q Q Q LQQ QQQQQ +Q QQQ Q Q
Sbjct: 2122 QQAAPPQPQ------PQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 113 bits (283), Expect = 5e-25
Identities = 82/184 (44%), Positives = 99/184 (53%), Gaps = 21/184 (11%)
Query: 146 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQQQQHPGKQAKEQQQ 202
LH QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQ A++QQQ
Sbjct: 584 LHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQ 643
Query: 203 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262
QQQQQQQ QQQ Q QQ QQQQ S Q L S P ++ LP+Q
Sbjct: 644 QQQQQQQ--------QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-------Q 688
Query: 263 PAEIQQLWKE-VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQS 321
+QQ+ + + G+ + + N+ + S N S P T +N Q
Sbjct: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPN--PCSNPNTGSGYMNSQQ 746
Query: 322 SVLS 325
S+L+
Sbjct: 747 SLLN 750
Score = 108 bits (270), Expect = 2e-23
Identities = 106/350 (30%), Positives = 147/350 (42%), Gaps = 88/350 (25%)
Query: 102 QQMQQILQQQ-------VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ 154
QQM +L Q QQ Q QQQQ QQQQ Q+ ++QQ+Q + QQ
Sbjct: 569 QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
Query: 155 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP--------------------- 193
QQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
Query: 194 ---------------GKQAKEQQQQQQ----------------------------QQQQL 210
G Q +QQ+Q Q QQ L
Sbjct: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
Query: 211 AAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLW 270
QQL+ ++Q LQ Q ++Q+Q LL LQ+Q L + P + + P +
Sbjct: 749 LNQQLMGKKQTLQRQIMEQKQQLL-LQQQMLAD---AEKIAPQDQINRHLSRPPPDYK-- 802
Query: 271 KEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKA-SPPITHHSIVNGQSSVLSARRD 329
+ V +M+ GG SST S N+++A + P++ H+I+ SS+LS
Sbjct: 803 DQRRNVGNMQPTAQYSGG--------SSTISLNSNQALANPVSTHTILTPNSSLLSTSHG 854
Query: 330 SSSHEETGASHT--LYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRS 377
+ + A +YG+ C P S+ Q + N + L +++
Sbjct: 855 TRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQN 904
Score = 52.4 bits (124), Expect = 1e-06
Identities = 115/549 (20%), Positives = 194/549 (35%), Gaps = 65/549 (11%)
Query: 9 TISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQ 68
+++NS+++ + Q A + G SG + + S E+ H QQ + + A RQ +
Sbjct: 392 SMANSALSTSSPIPSVPQSQAQPQTG--SGASRALPSWQEVSHAQQLKQIAANRQQHARM 449
Query: 69 QTSGLKSPKSSDKQRPLQVPVSVAMMTPQVI-TPQQMQQILQQQVLSPQQLQALLQQQQA 127
Q + ++ P S + I +P QQ Q SP A Q
Sbjct: 450 QQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQS-SPMPGVAGGSGQSK 508
Query: 128 VMLQQQQLQEFYKK--QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ---------- 175
VM YK + HL +L QQ+ Q + + +Q
Sbjct: 509 VMANYM-----YKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFN 563
Query: 176 QQQQQQQQQQQQQQQQHPGK---QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQH 232
Q QQ Q P ++QQQQQQQQQQ QQ QQQ Q QQ QQQQ
Sbjct: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQ 620
Query: 233 LLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLT 292
S+ Q Q Q+ +S + QQ ++ + + +
Sbjct: 621 QSSISAQ-------------QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS 667
Query: 293 TNNSSSTTSSNTSKASPPITHHSIVNG-QSSVLSARRDSSSHEETGASHTLYGHGVCKWP 351
+ + S S ++ P+ ++ Q+ ++ S ++ H++ G P
Sbjct: 668 SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSP 727
Query: 352 G---CESICEDFGQF--LKHLNNEHALDDRSTAQCRVQMQVVQ-QLEIQLSKERERL--- 402
C + G + L N+ + + T Q ++ Q Q L+ Q+ + E++
Sbjct: 728 SPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQ 787
Query: 403 QAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPS 462
+ HL P + K + + + T + Q P + T +T
Sbjct: 788 DQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILT---- 843
Query: 463 VITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL--IRQAIMES 520
PN + H + +P S N Y N P TY+ + Q +
Sbjct: 844 -------PNSSLLSTSHGTR--MPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQR 894
Query: 521 SDRQLTLNE 529
+ +QL N+
Sbjct: 895 NPKQLLANQ 903
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 113 bits (282), Expect = 7e-25
Identities = 82/164 (50%), Positives = 95/164 (57%), Gaps = 19/164 (11%)
Query: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ
Sbjct: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-------QQQQQQQQQQQFQAQQSA 195
Query: 172 QQQQQQ---QQQQQQQQQQQQQQHPGK---QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
QQQ Q QQQQQ QQQQQQQQH K Q ++Q QQQQQQ Q AQ + QQQ Q Q
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQ 253
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 269
Q QQQQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
Score = 108 bits (269), Expect = 2e-23
Identities = 85/190 (44%), Positives = 96/190 (50%), Gaps = 21/190 (11%)
Query: 92 AMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLL 151
+M TPQ Q LQQ L QQ Q QQQQ LQQQQ Q+ ++QQ Q +
Sbjct: 140 SMAVVSTATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQQQ--QQQQFQAQQSAM 196
Query: 152 QQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQ 204
QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+ Q +Q ++QQQQQ
Sbjct: 197 QQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
Query: 205 QQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQRQGLISIPPGQAALPV 253
QQQQQ A Q Q QQ +Q QQLQQ H Q PP P
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Query: 254 QSLPQAGLSP 263
Q PQ+ P
Sbjct: 317 QLPPQSQTQP 326
Score = 106 bits (265), Expect = 7e-23
Identities = 100/254 (39%), Positives = 119/254 (46%), Gaps = 40/254 (15%)
Query: 19 GMSTLSSQLDAGSRDGR----SSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLK 74
GM +L + S G+ +SG ++ V Q Q LQ Q+ LQQQ
Sbjct: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ---QVALQQQ----- 163
Query: 75 SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ 134
+Q+ Q A+ QQ QQ QQQ QQ A+ QQ QAV+ QQQQ
Sbjct: 164 -----QQQQQFQQQQQAAL--------QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQ 209
Query: 135 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQ 191
LQ+ +QQ+Q HL L Q QQQ QQQQQQ Q Q Q QQQQQQQQQQQQQQQQ Q
Sbjct: 210 LQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
Query: 192 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 251
P Q QQ Q Q QQL QM Q Q Q+ + P Q L
Sbjct: 267 QPPIQQPPMQQPQPPPSQ------ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--L 318
Query: 252 PVQSLPQAGLSPAE 265
P QS Q +S A+
Sbjct: 319 PPQSQTQPLVSQAQ 332
Score = 31.2 bits (69), Expect = 3.5
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 364 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 422
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 423 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 468
S + + + + Q P P P P+ Q PS + P S
Sbjct: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 113 bits (282), Expect = 7e-25
Identities = 82/164 (50%), Positives = 95/164 (57%), Gaps = 19/164 (11%)
Query: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ
Sbjct: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-------QQQQQQQQQQQFQAQQSA 195
Query: 172 QQQQQQ---QQQQQQQQQQQQQQHPGK---QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
QQQ Q QQQQQ QQQQQQQQH K Q ++Q QQQQQQ Q AQ + QQQ Q Q
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQ 253
Query: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 269
Q QQQQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
Score = 108 bits (269), Expect = 2e-23
Identities = 85/190 (44%), Positives = 96/190 (50%), Gaps = 21/190 (11%)
Query: 92 AMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLL 151
+M TPQ Q LQQ L QQ Q QQQQ LQQQQ Q+ ++QQ Q +
Sbjct: 140 SMAVVSTATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQQQ--QQQQFQAQQSAM 196
Query: 152 QQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQ 204
QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+ Q +Q ++QQQQQ
Sbjct: 197 QQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
Query: 205 QQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQRQGLISIPPGQAALPV 253
QQQQQ A Q Q QQ +Q QQLQQ H Q PP P
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Query: 254 QSLPQAGLSP 263
Q PQ+ P
Sbjct: 317 QLPPQSQTQP 326
Score = 106 bits (265), Expect = 7e-23
Identities = 100/254 (39%), Positives = 119/254 (46%), Gaps = 40/254 (15%)
Query: 19 GMSTLSSQLDAGSRDGR----SSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLK 74
GM +L + S G+ +SG ++ V Q Q LQ Q+ LQQQ
Sbjct: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ---QVALQQQ----- 163
Query: 75 SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ 134
+Q+ Q A+ QQ QQ QQQ QQ A+ QQ QAV+ QQQQ
Sbjct: 164 -----QQQQQFQQQQQAAL--------QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQ 209
Query: 135 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQ 191
LQ+ +QQ+Q HL L Q QQQ QQQQQQ Q Q Q QQQQQQQQQQQQQQQQ Q
Sbjct: 210 LQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
Query: 192 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 251
P Q QQ Q Q QQL QM Q Q Q+ + P Q L
Sbjct: 267 QPPIQQPPMQQPQPPPSQ------ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--L 318
Query: 252 PVQSLPQAGLSPAE 265
P QS Q +S A+
Sbjct: 319 PPQSQTQPLVSQAQ 332
Score = 63.2 bits (152), Expect = 8e-10
Identities = 68/256 (26%), Positives = 94/256 (36%), Gaps = 42/256 (16%)
Query: 40 TSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVI 99
T ++ V L QQQQ Q +Q LQQQ + + +Q +Q + Q +
Sbjct: 151 TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
Query: 100 TPQQ-------------------------------MQQILQQQVLSPQQLQALLQQQQAV 128
QQ +QQ QQQ QQ Q LQ Q +
Sbjct: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
Query: 129 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 186
QQ +Q+ + L QL Q Q Q Q QQ Q Q Q Q Q Q
Sbjct: 271 --QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
Query: 187 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS--I 244
Q Q PG Q Q + +V QQ +Q Q QQQ + + Q +++ +
Sbjct: 329 SQAQALPG-----QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
Query: 245 PPGQAALPVQSLPQAG 260
Q++LP+ S P G
Sbjct: 384 QVSQSSLPMLSSPSPG 399
Score = 50.1 bits (118), Expect = 7e-06
Identities = 71/259 (27%), Positives = 90/259 (34%), Gaps = 43/259 (16%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQR-----PLQVP-VSVAMMTPQVITPQQMQQ 106
QQQQ LQ QL LQQQ + + +Q P+Q P + P PQQ+QQ
Sbjct: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQ 292
Query: 107 I--LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ---------- 154
+ Q PQ Q + Q Q L Q + Q + L Q+L Q
Sbjct: 293 MHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
Query: 155 -------QQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQQQHPGK 195
Q Q QQQQ Q Q Q Q Q QQ Q Q P
Sbjct: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
Query: 196 QAKEQ--QQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAALP 252
Q Q Q Q +++ L Q Q ++ + S+P PG P
Sbjct: 413 QPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTP 472
Query: 253 VQS---LPQAGLSPAEIQQ 268
V + AG S AE QQ
Sbjct: 473 VNPSSVMSPAGSSQAEEQQ 491
Score = 31.2 bits (69), Expect = 3.5
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 364 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 422
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 423 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 468
S + + + + Q P P P P+ Q PS + P S
Sbjct: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 98.2 bits (243), Expect = 2e-20
Identities = 79/184 (42%), Positives = 90/184 (48%), Gaps = 30/184 (16%)
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITP----QQM 104
+LHLQ QQ +Q +Q QQQ S P Q+P P S Q P QQ
Sbjct: 416 VLHLQPQQIMQLQQQQ--QQQISQQPYP-----QQPPH-PFSQQQQQQQQAHPHQFSQQQ 467
Query: 105 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 164
Q QQQ+ PQQL QQ Q Q Q+F++ QQ QL Q L Q QQQ QQQ
Sbjct: 468 LQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQ 527
Query: 165 QQQQQQQQQQQQQQQQQQQQQQQQ-------------QQQHPGKQAKEQQQQQQ-----Q 206
QQQQ QQQQ Q+ QQQQQQQ Q Q Q P +Q +QQQQQQ Q
Sbjct: 528 QQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQ 587
Query: 207 QQQL 210
Q QL
Sbjct: 588 QHQL 591
Score = 90.5 bits (223), Expect = 5e-18
Identities = 79/190 (41%), Positives = 91/190 (47%), Gaps = 25/190 (13%)
Query: 90 SVAMMTPQVITPQQMQQILQQQVLSPQQLQAL-LQQQQAVMLQQQQLQEFYKKQQEQLHL 148
S +TP+ QQ QQ QQQ QQ L LQ QQ + LQQQQ Q+ ++ Q
Sbjct: 390 SQVKVTPETHMLQQQQQAQQQQ----QQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPP 445
Query: 149 QLLQQQQQQQQQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ-Q 201
QQQQQQQQ QQQ Q QQQ QQ + QQQ Q QQQH +Q Q Q
Sbjct: 446 HPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQ 505
Query: 202 QQQQQQQQLA------------AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG-Q 248
Q Q QQQQLA QQ + QQQL +M Q QQQQ + S L Q
Sbjct: 506 QHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQ 565
Query: 249 AALPVQSLPQ 258
+P Q PQ
Sbjct: 566 HQVPPQQPPQ 575
Score = 88.6 bits (218), Expect = 2e-17
Identities = 83/202 (41%), Positives = 100/202 (49%), Gaps = 28/202 (13%)
Query: 108 LQQQVLSPQQ----LQALLQQQQAV-----MLQQQQLQEFYKKQQEQLHLQ---LLQQQQ 155
L+QQV QQ A+L Q V MLQQQQ + ++Q LHLQ ++Q QQ
Sbjct: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
Query: 156 QQQQQQQQQQQQQQ------QQQQQQQQ----QQQQQQQQQQQQQQHPGKQAKEQQQQQQ 205
QQQQQ QQ QQ QQQQQQQQ Q QQQ Q QQQ HP +Q QQQ Q
Sbjct: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
Query: 206 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 265
QQ A Q F Q LQ QLQQQQ L LQ+Q + Q + Q L + + +
Sbjct: 490 PFQQQHALQQQFHQ--LQQHQLQQQQ-LAQLQQQHSLLQQQQQQQIQQQQLQR--MHQQQ 544
Query: 266 IQQLWKEVTGVH-SMEDNGIKH 286
QQ + T H S ++H
Sbjct: 545 QQQQMQSQTAPHLSQTSQALQH 566
Score = 71.2 bits (173), Expect = 3e-12
Identities = 79/262 (30%), Positives = 107/262 (40%), Gaps = 41/262 (15%)
Query: 110 QQVLSPQQLQALLQQQQAVM--LQQQ--QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
QQ+ P + +LQ A L+QQ Q+ + L Q+ + QQQQQ
Sbjct: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
Query: 166 QQQQQQ------------QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213
QQQQQQ Q QQQQQQQ QQ QQ HP Q ++QQQQQ Q + Q
Sbjct: 408 QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ-QQQQQQQAHPHQFSQQ 466
Query: 214 QLVFQQQLLQ--------MQQLQ--QQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 263
QL F QQ L QQLQ QQQH L Q L Q L Q L Q
Sbjct: 467 QLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQL-----QQHQLQQQQLAQLQQQH 521
Query: 264 AEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSV 323
+ +QQ ++ ++ ++ S T+ + S+ S + H
Sbjct: 522 SLLQQQQQQ-----QIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
Query: 324 LSARRDSSSHEETGASHTLYGH 345
++ S ++ H L+GH
Sbjct: 577 QQQQQPPPSPQQ----HQLFGH 594
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/153 (33%), Positives = 58/153 (37%), Gaps = 49/153 (32%)
Query: 48 ELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQI 107
+L QQQ ALQ Q Q Q+
Sbjct: 487 QLQPFQQQHALQ-------------------------------------QQFHQLQQHQL 509
Query: 108 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 167
QQQ+ QQ +LLQQQQ +QQQQLQ + QQQQQQQ Q Q
Sbjct: 510 QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMH------------QQQQQQQMQSQTAPHL 557
Query: 168 QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ 200
Q Q Q Q QQ QQQQQQQ P + Q
Sbjct: 558 SQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQ 590
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 95.1 bits (235), Expect = 2e-19
Identities = 67/174 (38%), Positives = 89/174 (51%), Gaps = 18/174 (10%)
Query: 66 LQQQTSGLKSPKSSDKQRPLQV---PVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL 122
L Q + SP++ + P + P+++ + Q++T + + + +P L+
Sbjct: 357 LSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAP-----LI 411
Query: 123 QQQQAVML---QQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 179
M+ Q+ + QQ Q+ LQ QQQQQQQ QQ QQQQ QQ Q QQ QQQ
Sbjct: 412 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 471
Query: 180 QQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ-QQLLQMQQLQQQQH 232
QQQ Q QQH QQQQQ QQQ+ QQL Q QQ LQ+QQLQ QH
Sbjct: 472 MQQQHFQHHMQQH------LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH 519
Score = 84.7 bits (208), Expect = 3e-16
Identities = 57/146 (39%), Positives = 72/146 (49%), Gaps = 13/146 (8%)
Query: 94 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 153
++P V T Q Q+ QQQ QQ+Q + QQQ LQQ Q+ + ++Q +Q H Q
Sbjct: 427 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQ----LQQHQMHQQIQQQMQQQHFQ--HH 480
Query: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213
QQ QQQQQ QQQ QQQ QQQ QQ+ Q QQ Q QH Q Q +Q A
Sbjct: 481 MQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH-------QSQPSPRQHSPVAS 533
Query: 214 QLVFQQQLLQMQQLQQQQHLLSLQRQ 239
Q+ + Q QQH +Q Q
Sbjct: 534 QITSPIPAIGSPQPASQQHQSQIQSQ 559
Score = 79.0 bits (193), Expect = 1e-14
Identities = 50/102 (49%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216
Q QQ Q Q QQQQQQQQQQ QQ QQQQ QQ Q Q +Q ++Q Q QQ L QQ
Sbjct: 432 QTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQH 491
Query: 217 FQQQLLQ---MQQLQQQQHLLSLQRQGLISIPPGQAALPVQS 255
QQQ+ Q QQLQQ+ L LQ S P + PV S
Sbjct: 492 LQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVAS 533
Score = 70.1 bits (170), Expect = 7e-12
Identities = 51/145 (35%), Positives = 65/145 (44%), Gaps = 16/145 (11%)
Query: 89 VSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK------Q 142
VS ++ T Q Q QQ QQQ + Q Q L Q Q +QQQ Q+ ++ Q
Sbjct: 427 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQ 486
Query: 143 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----------QH 192
Q+Q HLQ QQQ QQQ QQ+ Q QQ Q Q Q Q +Q Q
Sbjct: 487 QQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQ 546
Query: 193 PGKQAKEQQQQQQQQQQLAAQQLVF 217
P Q + Q Q Q Q Q+ +Q +F
Sbjct: 547 PASQQHQSQIQSQTQTQVLSQVSIF 571
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/188 (29%), Positives = 73/188 (38%), Gaps = 12/188 (6%)
Query: 2 MQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVE-LLHLQQQQALQA 60
M + T ++M N + L S + S S V T + + LQQQQ Q
Sbjct: 389 MNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQ 448
Query: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQA 120
+ +QQQ +Q+ Q M QQ QQ LQQQ+ + QQLQ
Sbjct: 449 QQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHL----QQQQQHLQQQI-NQQQLQQ 503
Query: 121 LLQQQQAVMLQQQQLQEFYKKQQ--EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
LQQ+ LQ QQLQ + Q + H + Q Q QQ Q Q Q Q
Sbjct: 504 QLQQR----LQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQ 559
Query: 179 QQQQQQQQ 186
Q Q Q
Sbjct: 560 TQTQVLSQ 567
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/47 (48%), Positives = 25/47 (53%)
Query: 193 PGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
P Q Q QQ Q QL QQ QQQ+ QMQQ Q QQH + Q Q
Sbjct: 423 PSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQ 469
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 95.1 bits (235), Expect = 2e-19
Identities = 67/174 (38%), Positives = 89/174 (51%), Gaps = 18/174 (10%)
Query: 66 LQQQTSGLKSPKSSDKQRPLQV---PVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL 122
L Q + SP++ + P + P+++ + Q++T + + + +P L+
Sbjct: 362 LSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAP-----LI 416
Query: 123 QQQQAVML---QQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 179
M+ Q+ + QQ Q+ LQ QQQQQQQ QQ QQQQ QQ Q QQ QQQ
Sbjct: 417 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 476
Query: 180 QQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ-QQLLQMQQLQQQQH 232
QQQ Q QQH QQQQQ QQQ+ QQL Q QQ LQ+QQLQ QH
Sbjct: 477 MQQQHFQHHMQQH------LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH 524
Score = 84.7 bits (208), Expect = 3e-16
Identities = 57/146 (39%), Positives = 72/146 (49%), Gaps = 13/146 (8%)
Query: 94 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 153
++P V T Q Q+ QQQ QQ+Q + QQQ LQQ Q+ + ++Q +Q H Q
Sbjct: 432 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQ----LQQHQMHQQIQQQMQQQHFQ--HH 485
Query: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213
QQ QQQQQ QQQ QQQ QQQ QQ+ Q QQ Q QH Q Q +Q A
Sbjct: 486 MQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH-------QSQPSPRQHSPVAS 538
Query: 214 QLVFQQQLLQMQQLQQQQHLLSLQRQ 239
Q+ + Q QQH +Q Q
Sbjct: 539 QITSPIPAIGSPQPASQQHQSQIQSQ 564
Score = 79.0 bits (193), Expect = 1e-14
Identities = 50/102 (49%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216
Q QQ Q Q QQQQQQQQQQ QQ QQQQ QQ Q Q +Q ++Q Q QQ L QQ
Sbjct: 437 QTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQH 496
Query: 217 FQQQLLQ---MQQLQQQQHLLSLQRQGLISIPPGQAALPVQS 255
QQQ+ Q QQLQQ+ L LQ S P + PV S
Sbjct: 497 LQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVAS 538
Score = 70.1 bits (170), Expect = 7e-12
Identities = 51/145 (35%), Positives = 65/145 (44%), Gaps = 16/145 (11%)
Query: 89 VSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK------Q 142
VS ++ T Q Q QQ QQQ + Q Q L Q Q +QQQ Q+ ++ Q
Sbjct: 432 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQ 491
Query: 143 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----------QH 192
Q+Q HLQ QQQ QQQ QQ+ Q QQ Q Q Q Q +Q Q
Sbjct: 492 QQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQ 551
Query: 193 PGKQAKEQQQQQQQQQQLAAQQLVF 217
P Q + Q Q Q Q Q+ +Q +F
Sbjct: 552 PASQQHQSQIQSQTQTQVLSQVSIF 576
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/188 (29%), Positives = 73/188 (38%), Gaps = 12/188 (6%)
Query: 2 MQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVE-LLHLQQQQALQA 60
M + T ++M N + L S + S S V T + + LQQQQ Q
Sbjct: 394 MNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQ 453
Query: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQA 120
+ +QQQ +Q+ Q M QQ QQ LQQQ+ + QQLQ
Sbjct: 454 QQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHL----QQQQQHLQQQI-NQQQLQQ 508
Query: 121 LLQQQQAVMLQQQQLQEFYKKQQ--EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
LQQ+ LQ QQLQ + Q + H + Q Q QQ Q Q Q Q
Sbjct: 509 QLQQR----LQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQ 564
Query: 179 QQQQQQQQ 186
Q Q Q
Sbjct: 565 TQTQVLSQ 572
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/47 (48%), Positives = 25/47 (53%)
Query: 193 PGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
P Q Q QQ Q QL QQ QQQ+ QMQQ Q QQH + Q Q
Sbjct: 428 PSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQ 474
>gi|50301236 forkhead box J1 [Homo sapiens]
Length = 421
Score = 91.3 bits (225), Expect = 3e-18
Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 16/155 (10%)
Query: 438 TSPQSLPQTPTTPTAPVTPITQGPSVI----TPASVPNVGAIRRRHSDKYNIPMSSEIAP 493
T P Q P + AP +P+ P+ + TP P R P ++
Sbjct: 57 TDPHGYHQVPGS-AAPGSPLAADPACLGQPHTPGK-PTSSCTSRSAPPGLQAPPPDDV-- 112
Query: 494 NYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVR 553
++ N V+PP++YATLI A+ S ++TL+ IY W T F YFR TW+N++R
Sbjct: 113 --DYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIR 170
Query: 554 HNLSLHKCFVRV-----ENVKGAVWTVDEVEYQKR 583
HNLSL+KCF++V E KG W +D +Y +R
Sbjct: 171 HNLSLNKCFIKVPREKDEPGKGGFWRIDP-QYAER 204
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 88.2 bits (217), Expect = 2e-17
Identities = 50/76 (65%), Positives = 54/76 (71%), Gaps = 2/76 (2%)
Query: 148 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
L+ Q+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ A +Q QQ
Sbjct: 52 LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
Query: 208 QQLAAQ--QLVFQQQL 221
Q + Q QL Q L
Sbjct: 112 QGTSGQAPQLFHSQTL 127
Score = 87.0 bits (214), Expect = 5e-17
Identities = 61/119 (51%), Positives = 68/119 (57%), Gaps = 17/119 (14%)
Query: 148 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
L +L++QQ+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQ
Sbjct: 49 LSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQA 96
Query: 208 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAAL-PVQSLPQAGLSPA 264
AA Q QQ Q Q Q S Q L + P PG L P P ++PA
Sbjct: 97 VAAAAVQQSTSQQATQGTSGQAPQLFHS---QTLTTAPLPGTTPLYPSPMTPMTPITPA 152
Score = 75.5 bits (184), Expect = 2e-13
Identities = 48/95 (50%), Positives = 58/95 (61%), Gaps = 12/95 (12%)
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
L+PQ +Q +L++QQ Q+ +QQ+Q QQQQQQQQQQQQQQQQQQQQQ
Sbjct: 38 LTPQPIQ---NTNSLSILEEQQRQQ---QQQQQ------QQQQQQQQQQQQQQQQQQQQQ 85
Query: 173 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
QQQQQQQQQQ QQ +QA + Q Q
Sbjct: 86 QQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
Score = 61.2 bits (147), Expect = 3e-09
Identities = 48/128 (37%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 66 LQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQV-ITPQQMQQILQQQVLSPQQLQALLQQ 124
L GL SP+ + +P+ MM +TPQ +Q +L QQ Q QQ
Sbjct: 7 LPPYAQGLASPQGAMTPG---IPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQ 63
Query: 125 QQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 184
QQ QQQQ Q+ ++QQ QQQQQQQQQQQQQ QQ QQ Q
Sbjct: 64 QQQQQQQQQQQQQQQQQQQ--------QQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTS 115
Query: 185 QQQQQQQH 192
Q Q H
Sbjct: 116 GQAPQLFH 123
Score = 30.0 bits (66), Expect = 7.8
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 199 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 258
E+QQ+QQQQQQ Q QQ QQQQ Q+Q Q Q++
Sbjct: 53 EEQQRQQQQQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAA 99
Query: 259 AGLSPAEIQQLWKEVTG 275
A + + QQ + +G
Sbjct: 100 AAVQQSTSQQATQGTSG 116
>gi|50345831 forkhead box J3 [Homo sapiens]
Length = 622
Score = 87.8 bits (216), Expect = 3e-17
Identities = 66/249 (26%), Positives = 113/249 (45%), Gaps = 42/249 (16%)
Query: 418 PSPKPLNLVSSVTMSKNMLETSPQ-----SLPQTPTTPTAPVTPITQGPSVITPASVPNV 472
PS L + S + S ++ PQ ++ ++ T A T I++ +++ P
Sbjct: 9 PSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDP------ 62
Query: 473 GAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYS 532
N + E E ++ D +PP++YA+LI AI S +++TL+EIY
Sbjct: 63 -----------NTTLDQE-----EVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQ 106
Query: 533 WFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRV-----ENVKGAVWTVDEVEYQ------ 581
W F Y+R + WKN++RHNLSL+KCF++V + KG+ W +D +
Sbjct: 107 WICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTR 166
Query: 582 -KRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQA 640
K+R++ + + T SLG ++ S LA + ++N + N +
Sbjct: 167 PKKRARSVERASTPYSIDSDSLGMECIISGSASPTLA---INTVTNKVTLYNTDQDGSDS 223
Query: 641 VHEDLNGSL 649
LN SL
Sbjct: 224 PRSSLNNSL 232
>gi|24497506 forkhead box A3 [Homo sapiens]
Length = 350
Score = 87.4 bits (215), Expect = 4e-17
Identities = 55/173 (31%), Positives = 83/173 (47%), Gaps = 16/173 (9%)
Query: 413 PSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNV 472
P P P+ PLN S +T++ P LP +P P+ P+ P P+ + P +
Sbjct: 27 PVTPVPTMAPLN--SYMTLNPLSSPYPPGGLPASPL-PSGPLAP--PAPAAPLGPTFPGL 81
Query: 473 GAIRRRHSDKYNIP-----MSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTL 527
G S Y P E+ Y A +PP++Y +LI AI ++ + LTL
Sbjct: 82 GVSGGSSSSGYGAPGPGLVHGKEMPKGYR-RPLAHAKPPYSYISLITMAIQQAPGKMLTL 140
Query: 528 NEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENV-----KGAVWTV 575
+EIY W F Y+R N W+N++RH+LS + CFV+V KG+ W +
Sbjct: 141 SEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWAL 193
>gi|31563338 forkhead box K2 [Homo sapiens]
Length = 660
Score = 83.2 bits (204), Expect = 8e-16
Identities = 68/252 (26%), Positives = 124/252 (49%), Gaps = 31/252 (12%)
Query: 396 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 455
S++RE+ +A + ++ +P SP +N+ ++ + L + ++ + P++P
Sbjct: 159 SEKREKQEA--SESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRG 216
Query: 456 PITQGPSV--ITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLI 513
+ G V + P+ + N+ A + P + + A + K+ D +PP++YA LI
Sbjct: 217 AGSSGYKVGRVMPSDL-NLMADNSQ-------PENEKEASGGDSPKD-DSKPPYSYAQLI 267
Query: 514 RQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRV-----ENV 568
QAI + D+QLTLN IY+ T+ + Y+R W+N++RHNLSL++ F++V E
Sbjct: 268 VQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPG 327
Query: 569 KGAVWTVD--------EVEYQKRRSQKITG-----SPTLVKNIPTSLGYGAALNASLQAA 615
KG+ W +D E ++KRR + + P ++ P S + L+A A
Sbjct: 328 KGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGA 387
Query: 616 LAESSLPLLSNP 627
SL +P
Sbjct: 388 QTPESLSREGSP 399
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 82.4 bits (202), Expect = 1e-15
Identities = 66/197 (33%), Positives = 84/197 (42%), Gaps = 13/197 (6%)
Query: 78 SSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQE 137
S+ P + + + +V+ P + + L P +L Q QQ +
Sbjct: 378 SATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRV 437
Query: 138 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 197
+ QQ LQ L Q + QQQQQQQQQQQQQQQQQQQQQQQQQQQ H
Sbjct: 438 LQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQ 497
Query: 198 KEQQQQQQ---QQQQLAAQQLVF------QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQ 248
QQ Q QQQQ+ QQ + Q Q + Q Q+Q L P Q
Sbjct: 498 DAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQ 557
Query: 249 AALPVQSLPQAGLSPAE 265
Q+ P+ SP E
Sbjct: 558 Q----QASPEYLTSPQE 570
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 82.4 bits (202), Expect = 1e-15
Identities = 66/197 (33%), Positives = 84/197 (42%), Gaps = 13/197 (6%)
Query: 78 SSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQE 137
S+ P + + + +V+ P + + L P +L Q QQ +
Sbjct: 378 SATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRV 437
Query: 138 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 197
+ QQ LQ L Q + QQQQQQQQQQQQQQQQQQQQQQQQQQQ H
Sbjct: 438 LQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQ 497
Query: 198 KEQQQQQQ---QQQQLAAQQLVF------QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQ 248
QQ Q QQQQ+ QQ + Q Q + Q Q+Q L P Q
Sbjct: 498 DAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQ 557
Query: 249 AALPVQSLPQAGLSPAE 265
Q+ P+ SP E
Sbjct: 558 Q----QASPEYLTSPQE 570
>gi|4885237 forkhead box C2 [Homo sapiens]
Length = 501
Score = 82.0 bits (201), Expect = 2e-15
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 8/110 (7%)
Query: 479 HSDKYNIPMSSEIAPNYEFYKNAD---VRPPFTYATLIRQAIMESSDRQLTLNEIYSWFT 535
H ++Y+ M AP + A V+PP++Y LI AI + ++++TLN IY +
Sbjct: 44 HPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIM 103
Query: 536 RTFAYFRRNAATWKNAVRHNLSLHKCFVRV-----ENVKGAVWTVDEVEY 580
F ++R N W+N++RHNLSL++CFV+V + KG+ WT+D Y
Sbjct: 104 DRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSY 153
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 82.0 bits (201), Expect = 2e-15
Identities = 40/137 (29%), Positives = 97/137 (70%), Gaps = 4/137 (2%)
Query: 101 PQQMQQILQQQV-LSPQQLQALLQQQQAVMLQQQQL---QEFYKKQQEQLHLQLLQQQQQ 156
PQ+ +++ +++ L + Q L +++Q QQQ+L Q+ +KQ+E+ Q ++++Q
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216
Q++++QQ+++++QQ +++Q+++++QQ +++Q++++ + +EQ++++++QQ QQL
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 217 FQQQLLQMQQLQQQQHL 233
+QQL + QQL+++Q L
Sbjct: 385 REQQLRREQQLRREQQL 401
Score = 80.1 bits (196), Expect = 7e-15
Identities = 50/190 (26%), Positives = 113/190 (59%), Gaps = 19/190 (10%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
++ Q + RQ LQ++ L+ + + +R Q QQ Q++ ++Q
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE------------EQQQQRLRREQQ 305
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ---QQQQQQQQ 169
L +Q + +QQ+ ++++ QE ++Q+E+ QL ++Q+++++QQ +Q++++++
Sbjct: 306 LRRKQEEERREQQE----ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 170 QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 229
QQ +++Q++++++QQ +++QQ +Q + +QQ +++QQ QQL +QQL + QQL++
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 230 QQHLLSLQRQ 239
+Q L Q +
Sbjct: 422 EQQLRREQEE 431
Score = 73.9 bits (180), Expect = 5e-13
Identities = 45/191 (23%), Positives = 115/191 (60%), Gaps = 20/191 (10%)
Query: 59 QAARQLLLQQQTSGLKSPKSSDKQRP---LQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115
Q R+ LL+ + G + + ++R Q + + ++ +++ +++
Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ----QQQQQQQQQQQQQQQ 171
++LQ +++Q L++Q+L+ ++Q+E+ Q L+++QQ Q++++++QQ+++++Q
Sbjct: 269 RELQE--EEEQLRKLERQELRR--ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 172 QQQQQQQQQQQQQQ---------QQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 222
Q++++QQ+++++QQ +QQ ++ ++ +EQQ +++Q+++ QQL +QQL
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 223 QMQQLQQQQHL 233
+ QQL+++Q L
Sbjct: 385 REQQLRREQQL 395
Score = 73.6 bits (179), Expect = 6e-13
Identities = 44/190 (23%), Positives = 109/190 (57%), Gaps = 15/190 (7%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
Q+Q+ LQ + L + + L+ + ++Q+ Q + +Q + Q++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQ------------QRLRREQQLRRKQEEE 313
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ---QQQQQQQ 169
QQ + QQ++ ++++ Q+ ++Q+E+ QL ++Q++++++QQ +Q+++++
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 170 QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 229
+QQ +++QQ +++QQ +++QQ +Q + +QQ +++QQ QQL +QQL + Q+ ++
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 230 QQHLLSLQRQ 239
+ +R+
Sbjct: 434 HEQKHEQERR 443
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/205 (21%), Positives = 122/205 (59%), Gaps = 16/205 (7%)
Query: 51 HLQQQQALQAARQLLLQQQTSGLK----SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ 106
H Q+++ Q R +++ LK + ++R Q+ Q + Q+ ++
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Query: 107 ILQQQVLSPQQL--------QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 158
LQQ++ S QQL + LL++++ L+Q++ ++ K++QE+ QLL+++++++
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 159 QQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
QQ+ +++Q+++ +Q+ ++++ +Q+++++Q+ +++ P ++ ++Q + ++Q++ QQ
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 215 LVFQQQLLQMQQLQQQQHLLSLQRQ 239
L +QQ + Q+L++++ L+++
Sbjct: 647 LRREQQERREQRLKREEEEERLEQR 671
Score = 72.0 bits (175), Expect = 2e-12
Identities = 30/138 (21%), Positives = 94/138 (68%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
++ ++ Q++ + + + +++ LQ+++ Q + Q+E+ L+ L++Q+ ++++Q
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 162 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 221
+++QQQQ+ +++QQ +++Q++++++QQ+++ ++ +EQQ+++++QQ Q+ +QQL
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 222 LQMQQLQQQQHLLSLQRQ 239
+ Q+ ++++ L +++
Sbjct: 352 RREQEEERREQQLRREQE 369
Score = 66.6 bits (161), Expect = 8e-11
Identities = 37/201 (18%), Positives = 121/201 (60%), Gaps = 17/201 (8%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
++++ LQ + LL+++ + + + +R + + Q++ ++ ++ LQ++
Sbjct: 991 REEEELQQEEEQLLREER---EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Query: 113 LSPQQLQALLQQQQAVMLQQ------QQLQEFYKKQQE--QLHLQLLQQQQQQQQQQQQQ 164
++ + L Q+++ ++ ++ Q+L+ Y+K++E Q QLL+++ +++++Q+++
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107
Query: 165 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------LVFQ 218
+Q +++++ QQ+++Q +++++++++Q +Q +E+++ QQ+++QL ++ +
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 219 QQLLQMQQLQQQQHLLSLQRQ 239
+Q + ++LQQ++ L + Q
Sbjct: 1168 RQYREEEELQQEEEQLLREEQ 1188
Score = 63.9 bits (154), Expect = 5e-10
Identities = 43/187 (22%), Positives = 105/187 (56%), Gaps = 20/187 (10%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
QQQQ L+ +QL +Q+ + + +Q+ + + Q+ ++Q
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQERR----------------EQQEERREQQ 338
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
L +Q + QQ + ++++ Q+ ++Q+E+ Q L+++QQ +++QQ +++QQ +++
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 173 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQH 232
QQ +++QQ +++QQ +++Q Q + +QQ +++Q++ +Q Q++ Q + +Q++
Sbjct: 399 QQLRREQQLRREQQLRREQ----QLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 233 LLSLQRQ 239
L+R+
Sbjct: 455 RDWLKRE 461
Score = 63.5 bits (153), Expect = 6e-10
Identities = 33/142 (23%), Positives = 95/142 (66%), Gaps = 7/142 (4%)
Query: 100 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 159
T + Q+ +QQ+ Q+ + ++++ + L++++ +E QQE+ QL ++Q+++++
Sbjct: 464 TERHEQERRKQQLKRDQEEE---RRERWLKLEEEERRE----QQERREQQLRREQEERRE 516
Query: 160 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQ 219
Q+ ++Q+++++ QQ+ + +QQ +++Q+++++Q ++ +++ +Q++++Q+L +Q +
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 220 QLLQMQQLQQQQHLLSLQRQGL 241
QLL+ ++ ++QQ L Q + L
Sbjct: 577 QLLKREEERRQQRLKREQEERL 598
Score = 62.4 bits (150), Expect = 1e-09
Identities = 45/204 (22%), Positives = 113/204 (55%), Gaps = 17/204 (8%)
Query: 48 ELLHLQQQQALQAA-RQLLLQQQTSGLKSPKS---SDKQR-------PLQVPVSVAMMTP 96
EL L++++ LQ R LQ++ GL+ + S +QR L+ T
Sbjct: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL 889
Query: 97 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156
Q Q +QQ+L ++ + ++++ Q+Q+ Q ++Q +Q QLL+++++
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ-- 214
++++Q++++Q ++ ++ QQ+++Q ++ +++++Q K+ +E+++ QQ+++QL ++
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 215 ----LVFQQQLLQMQQLQQQQHLL 234
+++Q + +LQQ++ L
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQL 1033
Score = 62.4 bits (150), Expect = 1e-09
Identities = 32/144 (22%), Positives = 90/144 (62%), Gaps = 2/144 (1%)
Query: 96 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155
PQ+ ++ QQ+ + ++ + LLQ+ + L++Q+ ++++++QL Q +++
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 156 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
Q++QQ ++Q+ +++ ++++Q +Q+ +Q+Q ++Q+++ +EQ + ++++QQL Q+
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 216 VFQQQLLQMQQLQQQQHLLSLQRQ 239
++ + +QL+Q++ L+ Q
Sbjct: 1770 --DRKFREEEQLRQEREEQQLRSQ 1791
Score = 61.2 bits (147), Expect = 3e-09
Identities = 41/191 (21%), Positives = 111/191 (58%), Gaps = 22/191 (11%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
+++Q L+ +QL +QQ + + + R Q Q+ QQ+++ +QQ+
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQ----------QLRREQQLRR--EQQL 419
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEF-YKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
QQL+ ++++ +Q+ +E K++QE+ L ++++ ++ +Q++++QQ ++
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 172 QQQ---------QQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 222
Q++ +++++++QQ++++QQ + ++ +EQ+ ++Q++++ Q+L +QQL
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 223 QMQQLQQQQHL 233
+ Q+ +++Q L
Sbjct: 540 REQEERREQLL 550
Score = 61.2 bits (147), Expect = 3e-09
Identities = 34/146 (23%), Positives = 96/146 (65%), Gaps = 6/146 (4%)
Query: 97 QVITPQQMQQILQQQVLSPQQL--QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ 154
Q+ QQ+++ +QQ+ QQL + L+++Q + +Q++ + K +QE+ +L ++Q
Sbjct: 394 QLRREQQLRR--EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 155 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
++++ +++++ ++ +Q++++QQ ++ Q+++++++ ++ + ++QQ++++QQL +Q
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 215 LVFQQQLLQMQQLQQ--QQHLLSLQR 238
++Q L+ Q+ ++ QQ L S Q+
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQ 537
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/193 (20%), Positives = 113/193 (58%), Gaps = 10/193 (5%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
L+++Q L+ +QL +QQ + +R Q+ + Q + +Q ++ +Q+
Sbjct: 383 LRREQQLRREQQLRREQQLR-----REQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Query: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ--QQQQQQQQ 169
++ Q L ++Q+ ++ +E + +QE+ QL + Q+++++++ + ++++++
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 170 QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ--- 226
+QQ++++QQ +++Q+++++Q+ ++ + QQ+ + +QQL +Q ++QLL+ ++
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 227 LQQQQHLLSLQRQ 239
L+Q++ L+R+
Sbjct: 558 LEQERREQRLKRE 570
Score = 60.5 bits (145), Expect = 5e-09
Identities = 28/135 (20%), Positives = 89/135 (65%), Gaps = 4/135 (2%)
Query: 105 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 164
+Q +++ L ++ Q L ++ + Q+++ Q +++ +Q QLL+++++++++Q+ +
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Query: 165 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 224
+Q +++++ QQ+++Q +++ +++++Q +Q +E+++ QQ+++QL ++ ++Q +
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 225 QQLQQQQHLLSLQRQ 239
Q ++++ LQRQ
Sbjct: 1198 QYREEEE----LQRQ 1208
Score = 59.7 bits (143), Expect = 9e-09
Identities = 42/170 (24%), Positives = 98/170 (57%), Gaps = 27/170 (15%)
Query: 97 QVITPQQMQQILQQQVLSPQQL---QALLQQQQAVMLQQ----QQL---QEFYKKQQEQL 146
Q + +Q ++ +QQ+ QQL Q L ++QQ QQ QQL Q+ ++QQ +
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 147 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQQQQQ 189
QL ++Q++++ +Q+ +Q++++Q+ +++Q Q++++QQ ++ Q+
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 190 QQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
++ + K +++++++QQ+ QQL +Q+ + Q+L++Q+ LQ++
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Score = 58.9 bits (141), Expect = 2e-08
Identities = 36/191 (18%), Positives = 114/191 (59%), Gaps = 9/191 (4%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
L+++Q L+ +QL +QQ L+ + +++ L+ + + Q+ +Q ++Q
Sbjct: 389 LRREQQLRREQQLRREQQ---LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 112 VLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 168
L +Q + L ++++ +Q++ ++ K+ QE+ + + +++++++QQ++++Q
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
Query: 169 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ 228
Q +++Q+++++Q+ ++Q+++++ +Q +QQ +++Q+ +QL+ +++ +++Q +
Sbjct: 506 QLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 229 QQQHLLSLQRQ 239
++Q L Q +
Sbjct: 563 REQRLKREQEE 573
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/164 (22%), Positives = 93/164 (56%), Gaps = 14/164 (8%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
++ QQ+ Q++ ++ + LLQ+++ L +Q+ + ++++QL Q ++ ++Q+ +
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 162 QQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPGKQAK----------EQQQQQQQQ 207
Q+ +++ +++QQ +QQ+Q Q++QQ ++Q G+Q + EQ +Q++++
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 208 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 251
QQL+ Q+ + +L + + +Q+Q ++ + + GQ L
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Score = 58.5 bits (140), Expect = 2e-08
Identities = 35/167 (20%), Positives = 101/167 (60%), Gaps = 6/167 (3%)
Query: 55 QQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLS 114
QQ L++ +QL +Q+ + K +++R Q + Q ++ Q+L+++
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ---EERRDQLLKRE--E 583
Query: 115 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 174
++ Q L ++Q+ + Q+ + +E + +QE+ Q L++++ +++++QQ + ++Q++++
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 175 QQQQQQQQQQQQQQQQQHPGKQAK-EQQQQQQQQQQLAAQQLVFQQQ 220
QQQ +++QQ++++Q+ + ++ + EQ+ +++ +++ Q+L ++Q
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690
Score = 58.5 bits (140), Expect = 2e-08
Identities = 27/139 (19%), Positives = 89/139 (64%), Gaps = 6/139 (4%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
+Q +Q +++ L ++ Q L ++++ Q+++ Q K+ +Q QLL ++ +++++Q
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 162 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------L 215
+++++ +++++ QQ+++Q +++++++++Q +Q +++ + QQ+++QL ++
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 216 VFQQQLLQMQQLQQQQHLL 234
++Q + ++LQQ++ L
Sbjct: 1045 ERERQYREEEELQQEEEQL 1063
Score = 58.5 bits (140), Expect = 2e-08
Identities = 42/209 (20%), Positives = 107/209 (51%), Gaps = 22/209 (10%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
+++Q Q + L +Q K K R + Q+ + QQ+ Q++
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ-------------------LLQQ 153
++ + LLQ+++ L +Q+ + +++ QL Q LLQ+
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQHPGKQAKEQQQQQQQQQQL 210
++QQ ++Q++ ++ ++++QQ ++Q++++ Q++QQ ++Q ++ +E++Q +Q+ +Q
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 211 AAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
++ +++L+ +QL+ ++ L+RQ
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/198 (17%), Positives = 116/198 (58%), Gaps = 18/198 (9%)
Query: 55 QQALQAARQLLLQQ----QTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQ 110
Q+ L+ +QLL ++ Q + + +++R + + Q++ ++ ++ Q+
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 111 QVLSPQQLQALLQQQQAVMLQQ------QQLQEFYKKQQE--QLHLQLLQQQQQQQQQQQ 162
+ ++ + L Q+++ ++ ++ Q+ ++ Y++++E Q QLL+++++++++Q+
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Query: 163 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------LV 216
++Q +++ + QQ+++Q ++++++++ Q +Q +E+++ QQ+++QL ++
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 217 FQQQLLQMQQLQQQQHLL 234
++Q + ++LQQ++ L
Sbjct: 1076 LERQYRKEEELQQEEEQL 1093
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/123 (21%), Positives = 80/123 (65%), Gaps = 4/123 (3%)
Query: 109 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 168
++++ +Q + L+++Q L++Q+ + + K+++QL Q +QQ +Q + ++ ++++Q
Sbjct: 1364 EEELRHQEQGRKFLEEEQR--LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 169 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ 228
Q +Q++ ++ ++++QQ ++Q++ +EQQ +Q++ ++ ++ + Q++ + QQL
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER--EEQQLH 1479
Query: 229 QQQ 231
+Q+
Sbjct: 1480 RQE 1482
Score = 56.2 bits (134), Expect = 1e-07
Identities = 37/182 (20%), Positives = 97/182 (53%), Gaps = 17/182 (9%)
Query: 50 LHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQ 109
LH QQ+Q + L++Q G + + D+ R + +Q++Q +
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQ--RRQDRDRKFR-------------EEEQLRQERE 1568
Query: 110 QQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQ 169
+Q LS Q+ + ++ + +Q+Q ++F + +Q+ + QQ +Q++ ++ ++ +Q
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
Query: 170 QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 229
Q++++QQ +Q++ ++ +++ +Q +EQQ + + ++ ++ + Q+ + QQL++
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG--EEQQLRR 1686
Query: 230 QQ 231
Q+
Sbjct: 1687 QE 1688
Score = 55.8 bits (133), Expect = 1e-07
Identities = 37/217 (17%), Positives = 117/217 (53%), Gaps = 9/217 (4%)
Query: 26 QLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGL--KSPKSSDKQR 83
+L R+ R + + E L +++Q L+ R+ +Q+ K K K+
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 84 PLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 143
L P+ Q+ ++ +++ Q+ + LL++++ +Q+ +++ KK +
Sbjct: 972 QLLGE------EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 144 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQQQQQQQHPGKQAKEQQQ 202
Q + L ++++++++ Q++++Q +++++ QQ+++Q ++++ +++Q +Q +++++
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 203 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
QQ+++QL ++ +++ + +Q ++++ L + Q
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/199 (21%), Positives = 108/199 (54%), Gaps = 21/199 (10%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQ-- 109
L++Q+ + R+ L+ Q G K + + R + Q+ ++ QQ+ Q
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 110 -------QQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQE---------QLHLQLLQQ 153
+Q LS Q+ ++++ + +Q++ ++F +++Q+ + QLLQ+
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 154 QQQQQQQQQQQQQQ-QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212
+++QQ +Q++ ++ +++QQ ++Q++ ++ ++Q+ + Q P ++ E++QQ +QQ+
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR--Q 1530
Query: 213 QQLVFQQQLLQMQQLQQQQ 231
++ + ++Q L+ Q+ QQ+
Sbjct: 1531 RKFLQEEQQLRRQERGQQR 1549
Score = 55.8 bits (133), Expect = 1e-07
Identities = 37/197 (18%), Positives = 109/197 (55%), Gaps = 11/197 (5%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
++QQ + R+ Q+ L+ + K R + + Q+ ++ ++IL+++
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFRE-EEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
L P++ + L++Q+ +++ Q +++++QL Q ++ ++++Q +Q++++QQ +
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
Query: 173 QQQ------QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ 226
QQ+ +++Q Q ++Q+Q+ +Q +Q + ++Q Q++ +Q ++Q++ + +Q
Sbjct: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874
Query: 227 LQQ----QQHLLSLQRQ 239
++ ++H+ Q++
Sbjct: 1875 ERERKLREEHIRRQQKE 1891
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/201 (19%), Positives = 111/201 (55%), Gaps = 12/201 (5%)
Query: 32 RDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSV 91
R+ R + E +LL ++Q+ + +QL +QQ + K +++ L+
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEE-RRQQQLRREQQERREQRLKREEEEERLE----- 669
Query: 92 AMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLL 151
Q + + ++ +Q++ +Q QA + + + Q QL+ +Q +++ +
Sbjct: 670 -----QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-QAKEQQQQQQQQQQL 210
+Q+ Q+++Q+Q++++++++ + Q Q++++ +QQQ+++Q+ Q + +++ ++ +Q+L
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Query: 211 AAQQLVFQQQLLQMQQLQQQQ 231
+A+ + +Q+ Q++ ++QQ
Sbjct: 785 SARPPLREQRERQLRAEERQQ 805
Score = 55.1 bits (131), Expect = 2e-07
Identities = 36/186 (19%), Positives = 104/186 (55%), Gaps = 7/186 (3%)
Query: 26 QLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPL 85
QL R+ R + + E L +++Q L R+ +Q+ + +Q
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 86 QVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQE- 144
Q+ P+ Q+ ++ +++ Q+ + LL++++ ++Q+L+ Y++++E
Sbjct: 1092 QL----LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR-RRQELERQYREEEEV 1146
Query: 145 -QLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203
Q QLL+++ +++++Q+ ++Q +++++ QQ+++Q +++Q++++Q+ + +E++ Q
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Query: 204 QQQQQQ 209
+Q+++Q
Sbjct: 1207 RQKRKQ 1212
Score = 55.1 bits (131), Expect = 2e-07
Identities = 26/136 (19%), Positives = 87/136 (63%), Gaps = 4/136 (2%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ----EFYKKQQEQLHLQLLQQQQQQ 157
Q+ +Q+L+++ ++ + Q ++ LQQ++ Q E K+++++L Q ++++ Q
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Query: 158 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF 217
Q+++Q +++ +++++Q+ ++Q +++++ QQ+++ ++ +E+++Q++++Q ++L
Sbjct: 1148 QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
Query: 218 QQQLLQMQQLQQQQHL 233
Q++ + + Q+ L
Sbjct: 1208 QKRKQRYRDEDQRSDL 1223
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/199 (21%), Positives = 101/199 (50%), Gaps = 19/199 (9%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
+++Q LQ + L +Q K + + R + + P++ +QQ+
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ------------Q 160
Q+ + LQ++Q + Q++ Q + ++ + L+Q++++QQ +
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLE 1584
Query: 161 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ--QQQQQQQLAAQQ---- 214
+Q+ ++Q+Q+++ + +QQ ++Q+ QQQ +Q ++ +E +Q Q++++QQL Q+
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 215 -LVFQQQLLQMQQLQQQQH 232
L + QL + ++ QQ +H
Sbjct: 1645 FLEEEPQLRRQEREQQLRH 1663
Score = 54.7 bits (130), Expect = 3e-07
Identities = 24/126 (19%), Positives = 84/126 (66%), Gaps = 3/126 (2%)
Query: 117 QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ---LLQQQQQQQQQQQQQQQQQQQQQQ 173
QL+ ++++ + + LQE +K+Q+ L + L +++++++++Q+Q++Q ++++Q
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 174 QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 233
QQ+++Q +++++++++Q +Q ++ ++ QQ+++QL ++ +++ + ++ ++++ L
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 234 LSLQRQ 239
+ Q
Sbjct: 997 QQEEEQ 1002
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/139 (19%), Positives = 95/139 (68%), Gaps = 12/139 (8%)
Query: 102 QQMQQIL--QQQVLSPQQLQALLQQQQAVMLQQQQL--QEFYKKQQEQLHLQLLQQQQQQ 157
Q+ +Q+L +++ Q+L+ ++++ + +++QL +E K+++++ Q ++++ Q
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 158 QQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQHPGKQAKEQQQQQQQQQQLAA 212
Q+++Q ++++++++Q+ ++Q +++++ QQ+++Q ++ P K+ +++ ++Q ++++
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 213 QQLVFQQQLLQMQQLQQQQ 231
Q+ ++QLL+ +Q +++Q
Sbjct: 1178 QE---EEQLLREEQEKRRQ 1193
Score = 54.3 bits (129), Expect = 4e-07
Identities = 40/175 (22%), Positives = 97/175 (55%), Gaps = 15/175 (8%)
Query: 109 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ-----------QQQ 157
+QQ+ ++ + LQ++Q L++Q+L+ ++ ++EQL + Q+Q +++
Sbjct: 1697 EQQLRRQERERKFLQEEQ--QLRRQELERKFR-EEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 158 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF 217
Q + ++++QQ ++Q++ ++ ++++Q +Q++++QQ +++ + ++++Q +Q +Q +
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 218 QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 272
QQ + +++Q L Q Q L Q Q Q S E Q+LW+E
Sbjct: 1814 PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE-KSRREEQELWQE 1867
Score = 53.9 bits (128), Expect = 5e-07
Identities = 33/159 (20%), Positives = 92/159 (57%), Gaps = 21/159 (13%)
Query: 102 QQMQQILQQQ--VLSPQQLQALLQQQQAVMLQQQQL--QEFYKKQQEQLHLQLLQQQQQQ 157
Q+ +Q+L+++ Q+L+ ++++ V +++QL +E K+++++L Q ++++ Q
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 158 QQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ- 213
Q+++Q ++Q++++Q++++Q +++++ Q+Q+++Q+ Q + + Q + +++ A +
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
Query: 214 -------------QLVFQQQLLQMQQLQQQQHLLSLQRQ 239
+ + QL Q Q QHLL Q++
Sbjct: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/144 (21%), Positives = 78/144 (54%), Gaps = 29/144 (20%)
Query: 117 QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ--- 173
QL++ +Q+ + + + QE +++QEQ + ++ + Q Q++++ +QQQ+++Q
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 174 --------------------------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Q+++Q + +++QQ++Q+ P ++ KEQ+++Q+++
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 208 QQLAAQQLVFQQQLLQMQQLQQQQ 231
++ Q L ++QL + ++ QQ Q
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQ 850
Score = 52.0 bits (123), Expect = 2e-06
Identities = 43/205 (20%), Positives = 106/205 (51%), Gaps = 14/205 (6%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
L+++Q L+ R +++ L+ + R Q + Q + Q+ + ++Q
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHR--QERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ----------QQQQQ 161
L Q+ + +++ + +QQ+ ++F +++Q+ + QQ++Q Q +Q+
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Query: 162 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQH-PGKQAKEQQQQQQQQQQLAAQQLVFQQQ 220
+++QQ +Q++ ++ + ++Q+ ++Q+Q+++ +Q +Q+ QQQ +Q ++ +Q
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626
Query: 221 LLQMQQLQQQQHLLSLQRQGLISIP 245
LLQ ++ +QQ H R+ L P
Sbjct: 1627 LLQERE-EQQLHRQERDRKFLEEEP 1650
Score = 51.6 bits (122), Expect = 3e-06
Identities = 31/181 (17%), Positives = 104/181 (57%), Gaps = 8/181 (4%)
Query: 63 QLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL 122
Q LLQ++ L+ + ++R Q + Q+ +Q+L+++ ++ +
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQE----RQYREEEQLQQEEEQLLREEREKRRRQERER 958
Query: 123 QQQQAVMLQQQQLQ----EFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
Q ++ LQQ++ Q E K+++++ + ++++ QQ+++Q +++++++++Q+ ++
Sbjct: 959 QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 179 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQR 238
Q +++ + QQ+++ ++ +E+++ Q++++Q ++ + Q++ + + ++ + L+R
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 239 Q 239
Q
Sbjct: 1079 Q 1079
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/133 (18%), Positives = 78/133 (58%)
Query: 109 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 168
+Q++ + L+ ++Q +QQ+ Q F +++E+ + +++++++ Q ++++Q
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 169 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ 228
Q++++ QQ Q+++ Q+ Q+++ +Q ++Q+ + Q +++ ++ + +QL+
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 229 QQQHLLSLQRQGL 241
++Q LL + + L
Sbjct: 901 KEQQLLQEEEEEL 913
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/131 (21%), Positives = 80/131 (61%), Gaps = 9/131 (6%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
++ +Q+LQ++ P + Q ++ + L+ Q+ + +++++L Q +++ +++QQ
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 162 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 221
+ Q+++QQ +Q + ++ ++++QQ +Q++ + +EQQ ++Q+++ ++ L
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE---------RKFL 1449
Query: 222 LQMQQLQQQQH 232
+ QQL+Q++H
Sbjct: 1450 EEEQQLRQERH 1460
Score = 49.7 bits (117), Expect = 1e-05
Identities = 30/138 (21%), Positives = 86/138 (62%), Gaps = 12/138 (8%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ----EQLHLQLLQQQQQ- 156
+Q+ Q ++Q L Q+ ++++ + Q+Q ++F +++Q ++ + L+++QQ
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEE--LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 157 ---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ--QQQQQQQQLA 211
+++QQ +Q + ++ ++++QQ +Q++ ++ ++++Q +Q +E++ +++QQ +Q
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 212 AQQLVFQQQLLQMQQLQQ 229
++ ++QLLQ ++ QQ
Sbjct: 1460 HRKFREEEQLLQEREEQQ 1477
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/122 (20%), Positives = 80/122 (65%), Gaps = 6/122 (4%)
Query: 119 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
++LLQ ++ Q++ Q ++ + QL + Q+++Q++Q+Q+++ + ++Q ++Q++
Sbjct: 107 ESLLQDRR-----QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL 161
Query: 179 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQR 238
+Q+ +Q++ ++ ++ +E+++++ +++QL + + ++ +QL++++ LL L+R
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE-LLELRR 220
Query: 239 QG 240
+G
Sbjct: 221 KG 222
Score = 49.3 bits (116), Expect = 1e-05
Identities = 40/200 (20%), Positives = 104/200 (52%), Gaps = 17/200 (8%)
Query: 48 ELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQI 107
E H QQQ+ Q R Q Q KS ++ L + + + ++ QQ
Sbjct: 752 ERAHRQQQEEEQR-RDFTWQWQAE----EKSERGRQRLSARPPLREQRERQLRAEERQQ- 805
Query: 108 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 167
++Q P++ + +Q++ ++++ +F +++++ + QQ Q+++ Q+ Q++
Sbjct: 806 -REQRFLPEEEEK--EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862
Query: 168 QQQQQQQQQQQQQQQQQQQQQQQQH-----PGKQA---KEQQQQQQQQQQLAAQQLVFQQ 219
++ Q+Q++ Q+ + Q ++++++++H P Q KEQQ Q+++++L ++ ++
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 220 QLLQMQQLQQQQHLLSLQRQ 239
+ Q +Q ++++ L + Q
Sbjct: 923 RQEQERQYREEEQLQQEEEQ 942
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/153 (22%), Positives = 86/153 (56%), Gaps = 24/153 (15%)
Query: 109 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ-------EQLHLQ-----LLQQQQQ 156
+QQV ++ + L+++Q L+Q++ ++F +++Q +QLH Q L+++QQ
Sbjct: 1436 EQQVRRQERERKFLEEEQ--QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 157 QQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQQ------QQQQHPGKQAKEQQQQQQQ 206
++Q++ ++ ++Q+ + Q+ + +++QQ +QQ Q++Q +Q + QQ++Q +
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 207 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
++ ++ + Q++ Q Q++ L+ Q
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Score = 48.9 bits (115), Expect = 2e-05
Identities = 37/169 (21%), Positives = 93/169 (55%), Gaps = 17/169 (10%)
Query: 81 KQRPLQVPVSVAMMTPQVITPQQ--MQQILQQQVLSPQQLQALLQQQQAVMLQQ-QQLQE 137
+QR Q+ Q P++ +Q +Q+ ++LQ L +++Q ++ QQLQE
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 138 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQQQQQQQ 184
QE + Q+Q++ Q+ + Q ++++ Q+Q +++QQ Q++++
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 185 Q-QQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQH 232
+ Q+++++ +Q +E+Q ++++Q Q +QL+ +++ + +Q +++Q+
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/186 (16%), Positives = 102/186 (54%), Gaps = 10/186 (5%)
Query: 54 QQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVL 113
+++ Q RQ +Q+ + + S+KQ L+ Q ++ +++ +Q+
Sbjct: 130 EEEPGQRRRQKRQEQERELAEGEEQSEKQERLE----------QRDRQRRDEELWRQRQE 179
Query: 114 SPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 173
++ + +++Q + + +EF ++Q + L +++ ++++QQQ++++Q + Q
Sbjct: 180 WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQ 239
Query: 174 QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 233
++++++ ++++ ++++ ++ + Q+Q++ Q+++ ++L Q+ + Q+ +QQQ
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 234 LSLQRQ 239
L ++Q
Sbjct: 300 LRREQQ 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/143 (20%), Positives = 86/143 (60%), Gaps = 14/143 (9%)
Query: 102 QQMQQIL-QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQ------QEQLHLQLLQQQ 154
Q +Q +L +QQ +Q + QQ+ +++QL+ +K+ + Q QLL+++
Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Query: 155 QQQQQQQQQQQQQQQQQQQ--QQQQQQQQQQQQ-----QQQQQQHPGKQAKEQQQQQQQQ 207
+++++++Q+ ++ ++++Q Q++++Q ++Q+ ++++ +H + K +++Q+ +
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384
Query: 208 QQLAAQQLVFQQQLLQMQQLQQQ 230
+Q ++ + ++Q L+ Q+ +QQ
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQ 1407
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/106 (23%), Positives = 59/106 (55%), Gaps = 7/106 (6%)
Query: 141 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ 200
+Q E L+ Q QQ Q +QQ++ ++Q++++ QQ+ + +++Q ++ K+AK +
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 201 QQQQQQQQQLAAQQ-------LVFQQQLLQMQQLQQQQHLLSLQRQ 239
++ Q+++QL ++ ++ + +QL Q++ L+RQ
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/119 (21%), Positives = 72/119 (60%), Gaps = 4/119 (3%)
Query: 108 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 167
LQ Q Q ++Q+ Q Q +E ++ +++L + ++Q+++Q + +++QQ
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ 805
Query: 168 QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ 226
++Q+ ++++++Q+++Q+++++ K+ + ++++Q Q++ AQQL ++ LQ Q
Sbjct: 806 REQRFLPEEEEKEQRRRQRRERE----KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/168 (16%), Positives = 86/168 (51%), Gaps = 29/168 (17%)
Query: 97 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156
Q + ++ ++ +QQ+L ++ + QQQ Q+++ Q ++++E+ Q L+++ +
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 157 QQQQQQQQQQQQQQQQQQQ-----------------------------QQQQQQQQQQQQ 187
+++++Q+ +++Q+Q +++ Q+ Q+++Q+Q++
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 188 QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235
++++ + +++++ +QQQ Q+ F Q ++ ++ + LS
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/172 (18%), Positives = 92/172 (53%), Gaps = 9/172 (5%)
Query: 68 QQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQA 127
+Q+ P+ + QR Q + Q+ ++ +QQ +Q + Q QA
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ-EEEQRRDFTWQWQA 773
Query: 128 VMLQQQQLQEFYKKQ--QEQLHLQLLQQQQQQQQQ----QQQQQQQQQQQQQQQQQQQQQ 181
++ Q + +EQ QL +++QQ++Q ++++++Q+++Q+++++++ Q
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 182 QQQQQQQQQQHPGKQAKEQQQ--QQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231
++++Q Q++ +Q +E++ Q+ Q+++ + +Q Q+ Q+++ ++++
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
Score = 40.4 bits (93), Expect = 0.006
Identities = 25/131 (19%), Positives = 68/131 (51%), Gaps = 12/131 (9%)
Query: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
Q +Q Q+ P+ Q + Q ++Q+ + + +EQ Q +Q+ +Q++
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170
Query: 162 QQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQHPGKQAKEQQQQQQQQQQ 209
++ +Q+Q+ Q++++++ +++Q Q ++Q ++ + + + ++++QQQ+
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230
Query: 210 LAAQQLVFQQQ 220
Q VFQ++
Sbjct: 231 RERQDRVFQEE 241
Score = 38.9 bits (89), Expect = 0.017
Identities = 19/103 (18%), Positives = 64/103 (62%), Gaps = 1/103 (0%)
Query: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 189
L+++ Q +K+QEQ ++Q ++Q++ +Q+ +Q++ ++ +Q+Q+ Q++++++
Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188
Query: 190 QQHPGKQAKEQQQQQ-QQQQQLAAQQLVFQQQLLQMQQLQQQQ 231
++ + K + ++ ++QL ++L+ ++ + ++ QQ++
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231
Score = 36.2 bits (82), Expect = 0.11
Identities = 39/220 (17%), Positives = 99/220 (45%), Gaps = 35/220 (15%)
Query: 48 ELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQI 107
E L +++Q L+ R+ +Q+ + +Q Q+ P+ Q++++
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL----LREEPEKRRRQELERQ 1169
Query: 108 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ------ 161
+++ Q+ + LL+++Q Q+++ Q +++E+L Q +Q+ + + Q+
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQERERQY---REEEELQRQKRKQRYRDEDQRSDLKWQ 1226
Query: 162 -------------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 202
+ +Q +Q + Q + +Q QQ Q +QQ ++ + ++
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Query: 203 QQQQQQQLAAQQLVFQQQ---LLQMQQLQQQQHLLSLQRQ 239
QQ+ + +QL ++Q + ++ Q+++ LL +R+
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
Score = 32.7 bits (73), Expect = 1.2
Identities = 28/158 (17%), Positives = 77/158 (48%), Gaps = 4/158 (2%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
QQ ++ ++ R+ ++Q L+ + + RP Q Q+ +Q Q++ Q++
Sbjct: 1786 QQLRSQESDRKFREEEQ---LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ-QQQQQQQQQQQQQQQQQ 171
+ + Q+++ +Q+ QE +K++++ +L ++ ++QQ+++Q+ +Q + +
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
Query: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 209
Q+ + + + Q P + + + Q+Q+ Q
Sbjct: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
>gi|40549454 T-cell leukemia virus enhancer factor [Homo sapiens]
Length = 431
Score = 80.9 bits (198), Expect = 4e-15
Identities = 43/100 (43%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 499 KNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSL 558
K+A +PP++++ LI AI S ++ L + EIYSW F YF WKN+VRHNLSL
Sbjct: 107 KSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSL 166
Query: 559 HKCFVRVE------NVKGAVWTVDEVEYQKRRSQKITGSP 592
+KCF +VE N KG++W VD EY+ Q + P
Sbjct: 167 NKCFQKVERSHGKVNGKGSLWCVDP-EYKPNLIQALKKQP 205
>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
Length = 490
Score = 80.1 bits (196), Expect = 7e-15
Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 7/104 (6%)
Query: 495 YEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRH 554
Y+ +N + +PP++++ LI AI +S ++L + +IY+W F YF WKN+VRH
Sbjct: 105 YDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRH 164
Query: 555 NLSLHKCFVRVENV------KGAVWTVDEVEYQKRRSQKITGSP 592
NLSL+KCF +V+ KG++W +D EY++ Q + +P
Sbjct: 165 NLSLNKCFKKVDKERSQSIGKGSLWCIDP-EYRQNLIQALKKTP 207
>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
Length = 468
Score = 80.1 bits (196), Expect = 7e-15
Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 7/104 (6%)
Query: 495 YEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRH 554
Y+ +N + +PP++++ LI AI +S ++L + +IY+W F YF WKN+VRH
Sbjct: 105 YDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRH 164
Query: 555 NLSLHKCFVRVENV------KGAVWTVDEVEYQKRRSQKITGSP 592
NLSL+KCF +V+ KG++W +D EY++ Q + +P
Sbjct: 165 NLSLNKCFKKVDKERSQSIGKGSLWCIDP-EYRQNLIQALKKTP 207
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.123 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,126,980
Number of Sequences: 37866
Number of extensions: 1455653
Number of successful extensions: 76878
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1005
Number of HSP's successfully gapped in prelim test: 543
Number of HSP's that attempted gapping in prelim test: 13556
Number of HSP's gapped (non-prelim): 15635
length of query: 715
length of database: 18,247,518
effective HSP length: 109
effective length of query: 606
effective length of database: 14,120,124
effective search space: 8556795144
effective search space used: 8556795144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.