Guide to the Human Genome
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Search of human proteins with 170014705

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170014705 SH3-domain binding protein 2 isoform a [Homo
sapiens]
         (561 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]   1176   0.0  
gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]   1176   0.0  
gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]   1176   0.0  
gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]   1176   0.0  
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    67   6e-11
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    67   6e-11
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    67   6e-11
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    67   6e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    64   3e-10
gi|221139926 NHS-like 1 [Homo sapiens]                                 63   6e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    63   6e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    63   6e-10
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             63   8e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   4e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   7e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    60   7e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    60   7e-09
gi|41281612 zinc finger protein 828 [Homo sapiens]                     60   7e-09
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    59   9e-09
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    59   9e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    59   1e-08
gi|110349719 titin isoform N2-A [Homo sapiens]                         58   2e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    58   3e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          58   3e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          58   3e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          58   3e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   57   3e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   57   3e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   57   3e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    57   3e-08

>gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]
          Length = 618

 Score = 1176 bits (3042), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60
           MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
Sbjct: 58  MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 117

Query: 61  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120
           FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
Sbjct: 118 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 177

Query: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180
           WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
Sbjct: 178 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 237

Query: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240
           DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
Sbjct: 238 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 297

Query: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
           KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
Sbjct: 298 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 357

Query: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360
           ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
Sbjct: 358 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 417

Query: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
           KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
Sbjct: 418 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 477

Query: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480
           QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
Sbjct: 478 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 537

Query: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540
           QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
Sbjct: 538 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 597

Query: 541 HVLPSHQSLLLRHPYGYTGPR 561
           HVLPSHQSLLLRHPYGYTGPR
Sbjct: 598 HVLPSHQSLLLRHPYGYTGPR 618


>gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]
          Length = 589

 Score = 1176 bits (3042), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60
           MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
Sbjct: 29  MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 88

Query: 61  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120
           FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
Sbjct: 89  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 148

Query: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180
           WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
Sbjct: 149 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 208

Query: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240
           DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
Sbjct: 209 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 268

Query: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
           KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
Sbjct: 269 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 328

Query: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360
           ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
Sbjct: 329 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 388

Query: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
           KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
Sbjct: 389 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 448

Query: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480
           QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
Sbjct: 449 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 508

Query: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540
           QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
Sbjct: 509 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 568

Query: 541 HVLPSHQSLLLRHPYGYTGPR 561
           HVLPSHQSLLLRHPYGYTGPR
Sbjct: 569 HVLPSHQSLLLRHPYGYTGPR 589


>gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]
          Length = 561

 Score = 1176 bits (3042), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60
           MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
Sbjct: 1   MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60

Query: 61  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120
           FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
Sbjct: 61  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120

Query: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180
           WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
Sbjct: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180

Query: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240
           DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
Sbjct: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240

Query: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
           KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
Sbjct: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300

Query: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360
           ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
Sbjct: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360

Query: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
           KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
Sbjct: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420

Query: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480
           QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
Sbjct: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480

Query: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540
           QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
Sbjct: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540

Query: 541 HVLPSHQSLLLRHPYGYTGPR 561
           HVLPSHQSLLLRHPYGYTGPR
Sbjct: 541 HVLPSHQSLLLRHPYGYTGPR 561


>gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]
          Length = 561

 Score = 1176 bits (3042), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60
           MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
Sbjct: 1   MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60

Query: 61  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120
           FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
Sbjct: 61  FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120

Query: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180
           WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
Sbjct: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180

Query: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240
           DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
Sbjct: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240

Query: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
           KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
Sbjct: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300

Query: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360
           ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
Sbjct: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360

Query: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
           KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
Sbjct: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420

Query: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480
           QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
Sbjct: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480

Query: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540
           QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
Sbjct: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540

Query: 541 HVLPSHQSLLLRHPYGYTGPR 561
           HVLPSHQSLLLRHPYGYTGPR
Sbjct: 541 HVLPSHQSLLLRHPYGYTGPR 561


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P SP  GR    +   P  PPPP+P+    A S      S TS  P P+ PPPPP     
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358

Query: 246 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 302
                          P  A   P VP        PP + +  APG+     PP       
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395

Query: 303 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 361
           PSP P       C T     +     +         L P  PP   PPP +  + P  + 
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446

Query: 362 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
                P    P  +  PG  VP + P PP+  +P  E    P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)

Query: 236 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 295
           PPPPP HG       A D+K  P C   A                 +   P +P   + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317

Query: 296 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 355
            F     P P P  P   A STSS     T+T                PP   PPP PA 
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361

Query: 356 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 407
             +   +     P + A PG+  P   P  PP ++   P A A P         LP+ E 
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 408 PQLPHLQRSPP 418
             LP     PP
Sbjct: 421 QGLPPPPPPPP 431


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P SP  GR    +   P  PPPP+P+    A S      S TS  P P+ PPPPP     
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358

Query: 246 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 302
                          P  A   P VP        PP + +  APG+     PP       
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395

Query: 303 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 361
           PSP P       C T     +     +         L P  PP   PPP +  + P  + 
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446

Query: 362 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
                P    P  +  PG  VP + P PP+  +P  E    P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)

Query: 236 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 295
           PPPPP HG       A D+K  P C   A                 +   P +P   + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317

Query: 296 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 355
            F     P P P  P   A STSS     T+T                PP   PPP PA 
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361

Query: 356 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 407
             +   +     P + A PG+  P   P  PP ++   P A A P         LP+ E 
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 408 PQLPHLQRSPP 418
             LP     PP
Sbjct: 421 QGLPPPPPPPP 431


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P SP  GR    +   P  PPPP+P+    A S      S TS  P P+ PPPPP     
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358

Query: 246 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 302
                          P  A   P VP        PP + +  APG+     PP       
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395

Query: 303 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 361
           PSP P       C T     +     +         L P  PP   PPP +  + P  + 
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446

Query: 362 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
                P    P  +  PG  VP + P PP+  +P  E    P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)

Query: 236 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 295
           PPPPP HG       A D+K  P C   A                 +   P +P   + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317

Query: 296 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 355
            F     P P P  P   A STSS     T+T                PP   PPP PA 
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361

Query: 356 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 407
             +   +     P + A PG+  P   P  PP ++   P A A P         LP+ E 
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 408 PQLPHLQRSPP 418
             LP     PP
Sbjct: 421 QGLPPPPPPPP 431


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P SP  GR    +   P  PPPP+P+    A S      S TS  P P+ PPPPP     
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358

Query: 246 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 302
                          P  A   P VP        PP + +  APG+     PP       
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395

Query: 303 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 361
           PSP P       C T     +     +         L P  PP   PPP +  + P  + 
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446

Query: 362 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
                P    P  +  PG  VP + P PP+  +P  E    P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)

Query: 236 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 295
           PPPPP HG       A D+K  P C   A                 +   P +P   + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317

Query: 296 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 355
            F     P P P  P   A STSS     T+T                PP   PPP PA 
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361

Query: 356 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 407
             +   +     P + A PG+  P   P  PP ++   P A A P         LP+ E 
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 408 PQLPHLQRSPP 418
             LP     PP
Sbjct: 421 QGLPPPPPPPP 431


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 85/287 (29%), Positives = 105/287 (36%), Gaps = 44/287 (15%)

Query: 186  PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
            P +P P   + A M P A PP P      P     P   + T   P   L  PPPK G P
Sbjct: 1094 PATPSP---KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK-GAP 1149

Query: 246  DVGLAAEDSKRDPLCPRRAEPCPRVPA-TPRR----MSDPPLSTMPTAPGLRKPPCFRES 300
                A   S +  L     +  P  PA TP      ++ P     PT P    P      
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209

Query: 301  ASPSPE--PWTPGHGACSTSSAAIMATATSRNCDKLKSFHL-SPRGPPTSEP----PPVP 353
            A+PSP+  P TP   A   S    +AT + +      +    SP+G P + P    P  P
Sbjct: 1210 ATPSPKGAPTTPA--ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267

Query: 354  ANKPKFLKIAEEDPPREAA-MPGLFVPPV------------APRPPALKLPVPE------ 394
            A  P  LK     PP + A  P +  PP             AP PPA   P P+      
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327

Query: 395  ----AMARPAVLPRPEK--PQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
                A   PAV P   K  P LP    S   G +  S S E P  P+
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEGPTPPA 1373



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 73/288 (25%), Positives = 111/288 (38%), Gaps = 29/288 (10%)

Query: 142  TSDSSSDTDSFYGAVERPVD-ISLSPYPTDNEDYEHDDEDDSYLE---PDSPEPGRLEDA 197
            T   S+  D+  G +  PV  +  S  P ++  ++   +  +      P SP+      A
Sbjct: 810  TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869

Query: 198  L--MHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSK 255
            +  + P     PP  TP  P+  ++P    F  +GP      P PK   P + + +   K
Sbjct: 870  VTPLSPKGVTLPPKETPT-PSVVNLP----FPKEGPAT----PAPKQA-PALSMTSSSPK 919

Query: 256  RDPLCPRRAEPCPR-VPATP--RRMSDPPLSTMPTAPGLRKPPCFRESASP--SPEPWTP 310
            +      RA P P+ +PA+P  +    PP +T P+  G    P  + + +P  +  P   
Sbjct: 920  K-----ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974

Query: 311  GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPRE 370
            G  A  +   A    A +    K      SP+G PT  PP V    PK    A   P   
Sbjct: 975  GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT--PPAVTPPSPKGSPAATPFPKGA 1032

Query: 371  AAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPE-KPQLPHLQRSP 417
            +  P    P     P A  LP        A LP P+  P  P L+ +P
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 63/243 (25%), Positives = 84/243 (34%), Gaps = 21/243 (8%)

Query: 186  PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
            P SP+ G    A   P   P PP  TP  P  S  P           P + PP PK G P
Sbjct: 1294 PPSPKGG---PATSPPKGAPTPPAATPPSPKGS--PGTPPPKGAPTPPAVTPPSPK-GTP 1347

Query: 246  DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSP 305
             +      SK  P  P   E      ATP     P ++      G   P    +  SP+ 
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407

Query: 306  EPWTP---------GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANK 356
             P +P           GA + S   +   A +    K      +P+G P +         
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467

Query: 357  PKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK--PQLPHLQ 414
            P     + ++PP    +     P  AP  PA   P+  A   PAV+P   K  P  P  +
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPA---PM-GAPTLPAVIPSSPKEVPATPSSR 1523

Query: 415  RSP 417
            R P
Sbjct: 1524 RDP 1526



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 67/230 (29%), Positives = 78/230 (33%), Gaps = 31/230 (13%)

Query: 186  PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
            P SP+ G    A   P   P PP  TP  P  S  P A  F      P    PP   G P
Sbjct: 993  PPSPKGG---PATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKGSP 1047

Query: 246  DVGLAAEDSKRDPLCPRRAEPCPRV-PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPS 304
                A    K  P  P    P P+  PATP       L   PT P    P      A+PS
Sbjct: 1048 ---AATPLPKGAPTTPAATLPSPKGGPATPS------LKGAPTPPAATPPSPKGGPATPS 1098

Query: 305  PEPWTPGHGACSTSSAAIMATATSRNCDKL-KSFHLSPRG----PPTSEPPPVPANKPKF 359
            P+       A   S    +AT   +       +   SP+G    PP    P  PA  P  
Sbjct: 1099 PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158

Query: 360  LKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPE-AMARPAVLPRPEKP 408
             K     PP          P  AP  PA   P P+  +A P+    P  P
Sbjct: 1159 PKGGLATPP----------PKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 72/275 (26%), Positives = 100/275 (36%), Gaps = 26/275 (9%)

Query: 184  LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPP----- 238
            + P SP+ G    +    P  P     +P+K   + + R  + T    G L PP      
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS-KGDLTPPAVTPVS 1442

Query: 239  ---PPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRM---SDPPLSTMPTAP-GL 291
                P    P  G A   SK DP  P    P P+ P  P+++   S P  +    AP G 
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502

Query: 292  RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT----ATSRNCDKLKSFHLSPRGPPTS 347
               P    S SP   P TP       +  A + +    AT    + L    ++   P  +
Sbjct: 1503 PTLPAVIPS-SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 348  EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR----PPALKLPVP-EAMARPAVL 402
               P P   P      E   P  A  P  +    +P+    PPA+  P P EA   PAV 
Sbjct: 1562 PAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620

Query: 403  -PRPEK-PQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
             P PEK P  P  + +P       S   + P  P+
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 51/227 (22%), Positives = 79/227 (34%), Gaps = 29/227 (12%)

Query: 186  PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG-- 243
            P    P  L++ L+ P     P +  P +      P+    ++  P P+ P P  K+G  
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKG----PQTKKSSATSP-PICPDPSAKNGSK 1727

Query: 244  ------LPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPRRMSDPPLSTMPTAPGLRKPPC 296
                   P   L  +         + A   P+ P A P   +  PL+       L KP  
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787

Query: 297  FRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP--PPVPA 354
               SA+PSP    P            +A +        + F  S  G     P  P  PA
Sbjct: 1788 ASVSAAPSPPVSLP------------LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835

Query: 355  NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAV 401
            ++ + L +   + P    +P   V    P P +  +PVP   A+  V
Sbjct: 1836 DEDELLPLIPPE-PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 65/269 (24%), Positives = 95/269 (35%), Gaps = 32/269 (11%)

Query: 202 PAYPPPPVPTPRKPAFSDMPRAHSFTSK---GPGPLLPPPP--------PKHGLPDVGLA 250
           P  PPP  P P++   S   +A  F S       PL  P P        P    P+    
Sbjct: 43  PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF 102

Query: 251 AEDSKRDPLCPRR---AEP--CPRVPATPRRMSDPPLSTMPTAP-GLRKPPCFRESASPS 304
             +    P+ P     A P   P +  TP   S  PL+ +  AP  ++K   F  +   S
Sbjct: 103 LPNLIGPPISPAALALASPMIAPTLKGTP--SSSAPLALVALAPHSVQKSSAFPPNLLTS 160

Query: 305 PEPWTPGH-GACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIA 363
           P        G+  T SA I  +    N +K+ S  + P    T  PP + +  P      
Sbjct: 161 PPSVAVAESGSVITLSAPIAPSEPKTNLNKVPS-EVVPNPKGTPSPPCIVSTVPYHCV-- 217

Query: 364 EEDPPREAAMPGLFVPPVAPRPPALKLPVPEA--MARPAVLPRPEKPQLPHLQR--SPPD 419
               P  +   G+   P       L +  P+       +VL  P+ P    L+   SPP 
Sbjct: 218 ---TPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA 274

Query: 420 GQSFRSFSFEKPRQPSQADTGGDDSDEDY 448
             S  + S   P   S   T G ++  D+
Sbjct: 275 ALSLSTQSL--PVVTSSQKTAGPNTPPDF 301


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 78/320 (24%), Positives = 117/320 (36%), Gaps = 62/320 (19%)

Query: 193  RLEDALMHPPAYPPPPVPTPRKPAFSD----MPRAHSFTSKGPG------PLLPPPPPKH 242
            +L+ A+  PPA PPPPVP+P  P  +D    +P     T    G      P+ PPPPP+ 
Sbjct: 919  KLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEA 978

Query: 243  GL-----PDVGLAAEDSKRDPLCP-------------RRAEPCPRVPATPRRMSD--PPL 282
             +     PD  L+       P+ P               +EP P  P  P+ M D  PP 
Sbjct: 979  LIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPF 1038

Query: 283  STM---PTAPGLRKPPCFRESASPSPEPWTPGHG-------ACSTSSAAIMATATSRNCD 332
            +      ++ G  +PP  +E  S  P P                 +S A  A  + R   
Sbjct: 1039 TNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQ 1098

Query: 333  KLKS-----FHLSPRG-----------PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGL 376
            + ++     +HL P                S+P  V ++ P   K + +     AA  G 
Sbjct: 1099 EQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERG- 1157

Query: 377  FVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQ 436
               PV+  P A      EA   P+  P P+       ++ PP  +  + F    P Q   
Sbjct: 1158 --GPVSRSPGAPSAGEAEARPSPSTTPLPDSSP---SRKPPPISKKPKLFLVVPPPQKDF 1212

Query: 437  ADTGGDDSDEDYEKVPLPNS 456
            A    ++  E    VP P +
Sbjct: 1213 AVEPAENVSEALRAVPSPTT 1232



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 31/150 (20%)

Query: 283 STMPTAPGLRKPPCFRESASPS-----PEPWTPGHGACSTSSAAIMATATSRNCDK---- 333
           S  PTA  L   P F +S SP+     P+P  P   +   SS +I +++TS +       
Sbjct: 856 SNTPTA--LTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEG 913

Query: 334 ---LKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALK- 389
              +K    +   PP   PPPVP+  P F   A+  P         F+PP  P     + 
Sbjct: 914 SGTMKKLDPAVGSPPAPPPPPVPS--PPFPCPADRSP---------FLPPPPPVTDCSQG 962

Query: 390 LPVPEAMARPAVLPRPEKPQLPHLQRSPPD 419
            P+P +   P   P P +  +P    SPPD
Sbjct: 963 SPLPHS---PVFPPPPPEALIPFC--SPPD 987



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 62/267 (23%), Positives = 92/267 (34%), Gaps = 28/267 (10%)

Query: 186  PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
            PDSP    L   L+     PP P   P+    +  P  +S   +     L PP  K    
Sbjct: 1002 PDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTK---- 1057

Query: 246  DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTM-----------PTAPGLR-K 293
                  E++ R P+     E    V   P R +    +             P AP    K
Sbjct: 1058 ------EETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLK 1111

Query: 294  PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVP 353
            P  F +S + + E  +    A  TSS    A ++S+          + RG P S  P  P
Sbjct: 1112 PSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQG----DHGSAAERGGPVSRSPGAP 1167

Query: 354  ANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHL 413
            +      + +    P   + P    PP++ + P L L VP      AV P     +    
Sbjct: 1168 SAGEAEARPSPSTTPLPDSSPSRKPPPIS-KKPKLFLVVPPPQKDFAVEPAENVSEALRA 1226

Query: 414  QRSPPDGQSFRSFSFEKPRQPSQADTG 440
              SP  G+   S    + ++ S A  G
Sbjct: 1227 VPSPTTGEE-GSVHSREAKESSAAQAG 1252


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 67/242 (27%), Positives = 88/242 (36%), Gaps = 32/242 (13%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P  P+P  L+       A  PP V  PRK A   +    S     P P  PP P     P
Sbjct: 260 PSQPKPKGLQ-------ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP--P 310

Query: 246 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAP-----GLRKPPCFRES 300
            +          P     +   P + AT   +  PPLS + T P      L  PP     
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370

Query: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL--SPRGPPTSEPPPVPANKPK 358
           + P+  P +P            +AT + +  + L + HL  +P  PP S P   P + P 
Sbjct: 371 SPPASPPLSP------------LATPSPQAPNAL-AVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 359 FLKIAEEDPPREAAMPGLFVPP--VAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRS 416
              ++    P   A P L  PP  V P PPA     P A   P   P    P L  L + 
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL-QLAKP 476

Query: 417 PP 418
           PP
Sbjct: 477 PP 478



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 72/258 (27%), Positives = 92/258 (35%), Gaps = 34/258 (13%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGP-GPLLPPPP---PK 241
           P SP        L  PPA PP    T        +   HSF    P  PL  PPP   P 
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSL--GSPTLQATHSFLPSPPLSPLATPPPQAPPA 360

Query: 242 HGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
             LP +          PL P  A P P+ P A    +   P S  P+      PP     
Sbjct: 361 LALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPF 413

Query: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSE-PPPVPANKPKF 359
           + P+  P +P     S +  ++ A           S  +SP   P  + PPP+ A   + 
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473

Query: 360 LKIAEEDPPREAAMP--GLFVPPV-----APRPPALKLPV----------PEAMARPAVL 402
            K   + PP  A  P   L  PP      AP  P+  LP+          P  +A P + 
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533

Query: 403 PRPEKPQLPHLQ--RSPP 418
             P  P  P LQ  R PP
Sbjct: 534 VPPSPPASPTLQAPRRPP 551



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 72/272 (26%), Positives = 96/272 (35%), Gaps = 24/272 (8%)

Query: 184 LEPDSPEPGRLEDALMHPP--AYPPPPVPTPRKPAFSDMPRAHSFTSKG--PGPLLPPPP 239
           L P +  P +   AL  PP  A P PP   P  P  +  P+A +  +      P  PPP 
Sbjct: 347 LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406

Query: 240 PKHGLPDVGLAAEDSKRDPLCPRRAEP---CPRVPATPRRMSDPPLSTMPTAPGLRKPPC 296
           P    P    A+         P +A P    P +   P   + PP+S   T P    PP 
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466

Query: 297 FR---ESASPSPEP----WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP 349
                + A P P+      TP   A  +  A+    A         S  +SP   P  + 
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASLPMSPLATPPPQA 523

Query: 350 PPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRP-PALKLPVPEAMARPAVLPRPEKP 408
           PPV A     L++    PP   A P L  P   P P P   +  P      A  P P   
Sbjct: 524 PPVLA--APLLQV----PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577

Query: 409 QLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG 440
           + P    S PD     S +   P +    D+G
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 609



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 63/238 (26%), Positives = 81/238 (34%), Gaps = 53/238 (22%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------ 239
           P SP           PP   PPP+  P        P+A    +  P   LP PP      
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502

Query: 240 ----PKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPAT---------PRRMSDP------ 280
               P   LP   LA    +  P+    A P  +VP +         PRR   P      
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559

Query: 281 --PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 338
             P  T+  APG   PP  R  +S    P   GH + +TS+            ++L+ + 
Sbjct: 560 SGPRLTLALAPGPPPPPS-RSPSSTLSGPDLAGHSSSATSTP-----------EELRGYD 607

Query: 339 LSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR-PPALKLPVPEA 395
             P G   + PPP           AE      AA      PP+A R  P   LP P A
Sbjct: 608 SGPEGGAAASPPP----------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 77/301 (25%), Positives = 99/301 (32%), Gaps = 58/301 (19%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPP------- 237
           +P +   G +  A +   A    P  T R PA     RA    +  PGP+  P       
Sbjct: 56  KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115

Query: 238 ---PPPKHGL-------PDVGLAAEDSKRDPL-CPRRAEPCPRVPATPRRMSDPPLSTMP 286
              P  + GL          G A E  KR  L    R +     P TP            
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175

Query: 287 TAPGLRKPPCFRESASPSPEPWTPG----------HGACSTSSAAIMATATSRNCDKLKS 336
           T  GL +P     + S  P P T G          H     S AA    +      +  S
Sbjct: 176 TEVGLPRP-----APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 230

Query: 337 FHLSPRGPPTSEP----------PPVPAN----KPK---FLKIAEEDPPREAAMPGLFVP 379
             LS    P S P          P  PA+    KPK    L+  +  PPR+ A P L   
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--G 288

Query: 380 PVAPRPPALKLP--VPEAMARPAVLPRPEKPQLPHLQRS----PPDGQSFRSFSFEKPRQ 433
           P++  P A   P   P   A P++   P  P  P  Q +     P  Q+  SF    P  
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348

Query: 434 P 434
           P
Sbjct: 349 P 349



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 51/181 (28%), Positives = 59/181 (32%), Gaps = 35/181 (19%)

Query: 227 TSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRA--------EPCPRVPATPRRMS 278
           T + PG   PPPP       V  AA    R PL  R          E  PR  A P R S
Sbjct: 26  TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR--AGPTRTS 83

Query: 279 DPPLSTMPTAPGLRKPPCFRES---------ASPSPEPWTPGHGACSTSSAAIMATATSR 329
            PP S      G R PP    S         AS +  P   G      S+   +A   + 
Sbjct: 84  RPPAS----GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139

Query: 330 NCDKLKSFHLSPR----GPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRP 385
              K  +     R    GP    P P  A + +     E   PR A       P   PRP
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPA-------PSARPRP 191

Query: 386 P 386
           P
Sbjct: 192 P 192



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 15/141 (10%)

Query: 186 PDSPEPGRLEDALMHPPAYPP--PPVPTPRKPAFSDMPRAHS----FTSKGPGPLLPPPP 239
           P    P  L   L+  P  PP  P +  PR+P       + S      +  PGP  PPPP
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPP 576

Query: 240 ---PKHGL--PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR-- 292
              P   L  PD+   +  +   P   R  +  P   A      D  L+    A   R  
Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636

Query: 293 KPPCFRESASPSPEPWTPGHG 313
            PP     A  +P PW P  G
Sbjct: 637 APPLAFRGAPGAPLPWPPATG 657


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 70/279 (25%), Positives = 108/279 (38%), Gaps = 44/279 (15%)

Query: 170 DNEDYEHDDEDD-SYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTS 228
           + +D E +++++ +  E   P   + E  L  PP  PP P P P  P  S  P       
Sbjct: 372 EEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP------- 424

Query: 229 KGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPAT-PRRMSDPPLSTMPT 287
             P PL PPPPP    P +        ++    +   P P VPAT  R+   PPL+    
Sbjct: 425 --PPPLCPPPPPPVSPPPLPSPPPPPAQE---EQEESPPPVVPATCSRKRGRPPLTPSQR 479

Query: 288 APGLRKPPCFRESASPSPEPWTPGHGACSTSS------AAIMATATSRNCDKLKSFHLSP 341
           A         RE+A   PE  +P     ST++      +  +A  ++     ++ F +  
Sbjct: 480 AE--------REAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM-- 529

Query: 342 RGPPTSEPPPVPANKPKFLK----IAEEDPPR--EAAMPGLFVPPVAPRPPALKLPVPEA 395
                   P V A   + +K      +EDPP+  +  +  +  PP+   PP  + P P  
Sbjct: 530 --------PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVP 581

Query: 396 MARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQP 434
               A  P      LP  +RS     +FR  S  +   P
Sbjct: 582 SPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 62/211 (29%), Positives = 77/211 (36%), Gaps = 51/211 (24%)

Query: 155  AVERPVDISLSPYPTDNEDYEHDDE-DDSYLEPDSPE---PGRLEDALMHPPAYPPPPVP 210
            A E    I  SP P+       D   D   L P +PE   P +  D  + P +   PP P
Sbjct: 1797 AAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP-P 1855

Query: 211  TPRKPAFSDMPRAHSFTSKGP------GPLLPPPPPK---HGLPDVGLAAEDSKRDPLCP 261
             PR  + + +   +   S+ P      GPL  P  P    H +P VG    D    P   
Sbjct: 1856 APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG--DPDFPAPPRRS 1913

Query: 262  RRAEP-CPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSA 320
            RR  P  PR P  P R + PPL T   +P LR PP                      +S 
Sbjct: 1914 RRPSPLAPRPP--PSRWASPPLKT---SPQLRVPP---------------------PTSV 1947

Query: 321  AIMATATSRNCDKLKSFHLSPRGPPTSEPPP 351
                T TS          L+P GP  S PPP
Sbjct: 1948 VTALTPTSGE--------LAPPGPAPSPPPP 1970



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 34/174 (19%)

Query: 201 PPAYPPPPVPT-PRKPAFSD----MPRAHSFTS-----KGPGPLLPPPPPKHGLPDVGLA 250
           PPA PPPP P+ P  PA S     + RA  FT      K    +L PPP   G P+    
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP--LGAPE---- 675

Query: 251 AEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTP 310
           A + +  P     AEP PR       +S P  + + T P        +   SP       
Sbjct: 676 APEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTP-------VKAEVSP------- 721

Query: 311 GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTS---EPPPVPANKPKFLK 361
            HGA + S+         +    L++  L    PP     +PPP P   P   K
Sbjct: 722 -HGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 43/182 (23%)

Query: 206  PPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAE 265
            PPPV  P  P         S+T       LPP P    LP VG+             R  
Sbjct: 2212 PPPVKQPPLPPTISPTAPTSWT-------LPPGPLLGVLPVVGVV------------RPA 2252

Query: 266  PCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPW----------------- 308
            P P  P     +S  P S    A  +++   F   + P+P P+                 
Sbjct: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQ 2312

Query: 309  TPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVP-ANKPKFLKIAEEDP 367
             PG G+   S    M T T R         L   G P  E  P P   +   L + E+ P
Sbjct: 2313 VPGLGSGGFSRVR-MKTPTVRGV-----LDLDRPGEPAGEESPGPLQERSPLLPLPEDGP 2366

Query: 368  PR 369
            P+
Sbjct: 2367 PQ 2368



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 50/190 (26%), Positives = 65/190 (34%), Gaps = 30/190 (15%)

Query: 268  PRVPATPRRMSDPPLST---MPTAPGLRKP-----PCFRESASPSPEPWTPGHGACSTSS 319
            P   + P    DPPL T   +P AP    P     P  R  +  +P P        S S 
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPP-----APRSFSG 1862

Query: 320  AAIMATATSRNCDKLKSFHLSPR---GPPTSEPPPVPA-NKPKFLKIAEEDPPREAAMPG 375
            A I     S +   L      P    G P+S    +P    P F       PPR +  P 
Sbjct: 1863 ARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDF-----PAPPRRSRRPS 1917

Query: 376  LFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
                P+APRPP  +   P     P +   P    +  L  +P  G+   +     P  P 
Sbjct: 1918 ----PLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTAL--TPTSGE--LAPPGPAPSPPP 1969

Query: 436  QADTGGDDSD 445
              D G D  D
Sbjct: 1970 PEDLGPDFED 1979



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 7/84 (8%)

Query: 182  SYLEPDSPEPGRLEDALMHPPAYPPPPVPT-------PRKPAFSDMPRAHSFTSKGPGPL 234
            S+  P  P  G L    +  PA PPPP P        P  P    +      T  G  P 
Sbjct: 2231 SWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP 2290

Query: 235  LPPPPPKHGLPDVGLAAEDSKRDP 258
             PPP     L + G A+ED+ + P
Sbjct: 2291 APPPYKAPRLDEDGEASEDTPQVP 2314



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 26/124 (20%)

Query: 153  YGAVERPVD-ISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPP--- 208
            Y    RP+  +S  P P+            +  +PD P P R       P A  PPP   
Sbjct: 1870 YSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPR-RSRRPSPLAPRPPPSRW 1928

Query: 209  ------------VPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDV-------GL 249
                        VP P     +  P +      GP P   PPPP+   PD        GL
Sbjct: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAP--SPPPPEDLGPDFEDMEVVSGL 1986

Query: 250  AAED 253
            +A D
Sbjct: 1987 SAAD 1990


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 90/345 (26%), Positives = 121/345 (35%), Gaps = 51/345 (14%)

Query: 186  PDSPEPGRLEDALMHP--PAYPPPPVPTPRKPAFSDMPRAHSFTSKGP-GPLLPPPPPKH 242
            P   EP     A+  P  P  P   VPTP +P     P A   T + P  P    P P+ 
Sbjct: 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPTSPAAAVPTPEE 1103

Query: 243  GLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP-------- 294
              P    AA  +  +P  P  A P P  PA+P      P      AP +  P        
Sbjct: 1104 --PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161

Query: 295  --PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD---------KLKSFHLSPRG 343
              P   ESASP+    TP   A   +  A +   TS              L+ F      
Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221

Query: 344  PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPV-APRPPALKLPVPEAMARPAV- 401
             PTSE P   A        A    P E   P   VP +  P   A  +  PE ++ PA  
Sbjct: 1222 VPTSEEPASLA--------AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273

Query: 402  LPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNT 461
            +P PE+P  P    S          + E+P  P+ A    + +      VP P    +  
Sbjct: 1274 VPTPEEPASPAAAVS----------NLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA 1323

Query: 462  TESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSN 506
                 +E +    SP G P  G+    +S   S +   V +E S+
Sbjct: 1324 AAVPPMEEV----SPIGVPFLGVSAHTDSVPISEEGTPVLEEASS 1364



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 61/245 (24%), Positives = 81/245 (33%), Gaps = 49/245 (20%)

Query: 195  EDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDS 254
            ED     P  P   V  P +P  + +  +       P   +P P                
Sbjct: 967  EDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP---------------- 1010

Query: 255  KRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP----PCFRESASPSPEPWTP 310
              +P  P  A P P  P +P     PP    PT+P    P    P    +A P+PE    
Sbjct: 1011 -EEPTSPAAAVPTPEEPTSPAAAVPPP--EEPTSPAAAVPTPEEPTSPAAAVPTPEE--- 1064

Query: 311  GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPRE 370
                  TS AA + T               P  P  + P P     P     A    P E
Sbjct: 1065 -----PTSPAAAVPTPE------------EPTSPAAAVPTPEEPTSP----AAAVPTPEE 1103

Query: 371  AAMPGLFVP-PVAPRPPALKLPVPEAMARP-AVLPRPEKPQLPHLQRSPPDGQSFRSFSF 428
               P   VP P  P  PA  +P PE  A P A +P PE+P  P      P+  +  + + 
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163

Query: 429  EKPRQ 433
              P +
Sbjct: 1164 PTPEE 1168



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 55/218 (25%), Positives = 74/218 (33%), Gaps = 21/218 (9%)

Query: 273  TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD 332
            T   +S P  +T+P             +A  SPE   P   A  T          S    
Sbjct: 897  TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWA 956

Query: 333  KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP---------PREAAMPGLFVP-PVA 382
             L           T E P  PA        A E+P         P E A P   VP P  
Sbjct: 957  ALAITVPITEEDGTPEGPVTPATTVH----APEEPDTAAVRVSTPEEPASPAAAVPTPEE 1012

Query: 383  PRPPALKLPVPEAMARP-AVLPRPEKPQLPHLQRSPPDGQSFRSFSF---EKPRQPSQAD 438
            P  PA  +P PE    P A +P PE+P  P      P+  +  + +    E+P  P+ A 
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072

Query: 439  TGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSP 476
               ++       VP P      T+ +  V    + TSP
Sbjct: 1073 PTPEEPTSPAAAVPTPEE---PTSPAAAVPTPEEPTSP 1107


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 66/241 (27%), Positives = 84/241 (34%), Gaps = 50/241 (20%)

Query: 201 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPP---PPKHGLPDVGLAAEDSKRD 257
           PP   P P+  P  P  +  P   S  +  P P  PP    PP  GLP            
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALASPPLQGLPS----------P 609

Query: 258 PLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 317
           PL P    P    P  P  ++ PPL   P+ P     P     A+PSP+         + 
Sbjct: 610 PLSPLATPP----PQAPPXLALPPLQAPPSPPA---SPPLSPLATPSPQ---------AP 653

Query: 318 SSAAIMATATSRNCDKLKSFHL--SPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPG 375
           ++ A+               HL  +P  PP S P   P + P    ++    P   A P 
Sbjct: 654 NALAV---------------HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698

Query: 376 LFVPP--VAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQ 433
           L  PP  V P PPA     P A   P   P    P L  +  SPP        +   PR 
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL-QVPPSPPASPPMSPSATPPPRV 757

Query: 434 P 434
           P
Sbjct: 758 P 758



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 79/304 (25%), Positives = 103/304 (33%), Gaps = 45/304 (14%)

Query: 159 PVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPP------PPVPTP 212
           P    LSP  T +    +         P SP P     A   PPA PP      PP   P
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696

Query: 213 ---RKPAFSDMPRAHSFTSKGPGPLLPP-PPPKHGLPDVGLAAEDSKRDPLCPRRAEPCP 268
                P     P   +     P    PP  PP    P + +        P+ P  A P P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP-SATPPP 755

Query: 269 RVP----ATPRRMSDPPLSTMPTAPGLRKPPCFRES-------ASPSPEPWTPGHGACST 317
           RVP    A P ++   P +++P +P  + PP    +       A PSP    PG    S 
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815

Query: 318 SSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLF 377
           S+                S  +SP   P  + PPV A     L++    PP   A P L 
Sbjct: 816 SA----------------SLPMSPLATPPPQAPPVLA--APLLQV----PPSPPASPTLQ 853

Query: 378 VPPVAPRP-PALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQ 436
            P   P P P   +  P      A  P P   + P    S PD     S +   P +   
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913

Query: 437 ADTG 440
            D+G
Sbjct: 914 YDSG 917



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/293 (26%), Positives = 104/293 (35%), Gaps = 29/293 (9%)

Query: 201 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLC 260
           P A P PP   PRK   S     HS T   P     P     GL      +  S   PL 
Sbjct: 194 PSARPRPPTEGPRKSVSS--ASEHSTTEPSPAARRRPSAGG-GLQRPASRSLSSSATPLS 250

Query: 261 -PRRAEPCPR-VPATPRRMSDP-PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 317
            P R+ P  R  P  P   S P P       P    PP  R+ A+P+  P +    A  +
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPS 308

Query: 318 SSAAIMATATSRNCDKLKSFHLSPRGPPTSEP----PPVPANKPKF--LKIAEEDPPREA 371
            S          +          P  PP + P    PP P+  P    L      PP +A
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368

Query: 372 AMPGLFVPPVAPRPPALKLP---VPEAMARPAVLPRPEKPQLPHLQRS----PPDGQSFR 424
             P +  PP+   P    +P   VP ++  P++   P    L  LQ +     P  Q+  
Sbjct: 369 P-PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427

Query: 425 SFSFEKPRQ-------PSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERL 470
           SF    PRQ       PS+  +   DS      + LP S  + T+ S  V  L
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 64/239 (26%), Positives = 83/239 (34%), Gaps = 49/239 (20%)

Query: 184 LEPDSPEPGRLEDALMHPPAY--PPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP-- 239
           + P +  P R+   L  PP    P PP   P  P     P+A    +  P   LP PP  
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806

Query: 240 --------PKHGLPDVGLAAEDSKRDPLCPR---RAEPCPRVPAT---PRRMSDP----- 280
                   P   LP   LA    +  P+      +  P P    T   PRR   P     
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866

Query: 281 ---PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSF 337
              P  T+  APG   PP  R  +S    P   GH + +TS+            ++L+ +
Sbjct: 867 VSGPRLTLALAPGPPPPPS-RSPSSTLSGPDLAGHSSSATSTP-----------EELRGY 914

Query: 338 HLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR-PPALKLPVPEA 395
              P G   + PPP           AE      AA      PP+A R  P   LP P A
Sbjct: 915 DSGPEGGAAASPPP----------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 963



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 73/271 (26%), Positives = 95/271 (35%), Gaps = 47/271 (17%)

Query: 184 LEPDSPEPGRLEDALMHPPAYPP---------PPVPTPRKPAFSDMPRA---HSFTSKGP 231
           L P SP        L  PPA PP         PP+  P  P+   +P     HS TS   
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP--PSLQTIPPIQVPHSLTS--- 397

Query: 232 GPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA-TPRRMSDP--PLSTMPTA 288
            P L  PP    L    L A  S   P            P  T   ++ P  P ST P +
Sbjct: 398 -PSLQAPPSPLALSS--LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454

Query: 289 PGLRKP------PCFRESASPSPEPWT------PGHGACSTSSAAIMATATSRNCDKLKS 336
           P L+ P      P  + S SP+  P +      P     S +S +  A  +S     L++
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514

Query: 337 FHLSPRGPPTSEPPPVPANKPKFLKIAE-EDPPREAAMPGLFVPPVAPRPPALKLPVPEA 395
              S   PP+ + PP     P    +     PP + A   L  P +   P     P+ +A
Sbjct: 515 --QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL-QA 571

Query: 396 MARPAVLPRPE--------KPQLPHLQRSPP 418
              P   P PE         PQ P    SPP
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPP 602



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 15/141 (10%)

Query: 186 PDSPEPGRLEDALMHPPAYPP--PPVPTPRKPAFSDMPRAHS----FTSKGPGPLLPPPP 239
           P    P  L   L+  P  PP  P +  PR+P       + S      +  PGP  PPPP
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPP 884

Query: 240 ---PKHGL--PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR-- 292
              P   L  PD+   +  +   P   R  +  P   A      D  L+    A   R  
Sbjct: 885 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 944

Query: 293 KPPCFRESASPSPEPWTPGHG 313
            PP     A  +P PW P  G
Sbjct: 945 APPLAFRGAPGAPLPWPPATG 965



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 47/189 (24%), Positives = 57/189 (30%), Gaps = 42/189 (22%)

Query: 227 TSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRA---------------------- 264
           T + PG   PPPP       V  AA    R PL  R                        
Sbjct: 26  TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85

Query: 265 ---EPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAA 321
               P  R PA+ R    PP     T+PG   P      AS +  P   G      S+  
Sbjct: 86  SSRNPASRPPASGRGERAPPAKN--TSPG---PVSSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 322 IMATATSRNCDKLKSFHLSPR----GPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLF 377
            +A   +    K  +     R    GP    P P  A + +     E   PR A      
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPA------ 193

Query: 378 VPPVAPRPP 386
            P   PRPP
Sbjct: 194 -PSARPRPP 201


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 73/260 (28%), Positives = 93/260 (35%), Gaps = 34/260 (13%)

Query: 184 LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGP-GPLLPPPP--- 239
           L P SP        L  PPA PP    T        +   HSF    P  PL  PPP   
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSL--GSPTLQATHSFLPSPPLSPLATPPPQAP 397

Query: 240 PKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPRRMSDPPLSTMPTAPGLRKPPCFR 298
           P   LP +          PL P  A P P+ P A    +   P S  P+      PP   
Sbjct: 398 PALALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPS------PPVQA 450

Query: 299 ESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSE-PPPVPANKP 357
             + P+  P +P     S +  ++ A           S  +SP   P  + PPP+ A   
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510

Query: 358 KFLKIAEEDPPREAAMP--GLFVPPV-----APRPPALKLPV----------PEAMARPA 400
           +  K   + PP  A  P   L  PP      AP  P+  LP+          P  +A P 
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570

Query: 401 VLPRPEKPQLPHLQ--RSPP 418
           +   P  P  P LQ  R PP
Sbjct: 571 LQVPPSPPASPTLQAPRRPP 590



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 68/265 (25%), Positives = 92/265 (34%), Gaps = 48/265 (18%)

Query: 186 PDSPEPGRLEDALMHPPAYPPP--------------PVPTPRK---------PAFSDMPR 222
           P  P+P  L+   + PP   PP              P+ TP           P     P 
Sbjct: 269 PSQPKPKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326

Query: 223 AHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPL 282
           + S T +   PL   PP     P +          P     +   P + AT   +  PPL
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386

Query: 283 STMPTAP-----GLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSF 337
           S + T P      L  PP     + P+  P +P            +AT + +  + L + 
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSP------------LATPSPQAPNAL-AV 433

Query: 338 HL--SPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPP--VAPRPPALKLPVP 393
           HL  +P  PP S P   P + P    ++    P   A P L  PP  V P PPA     P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493

Query: 394 EAMARPAVLPRPEKPQLPHLQRSPP 418
            A   P   P    P L  L + PP
Sbjct: 494 SATPPPQAPPPLAAPPL-QLAKPPP 517



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 64/232 (27%), Positives = 80/232 (34%), Gaps = 53/232 (22%)

Query: 198 LMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPP---PPPKHGLPDVGLAAED- 253
           L  P    P    TPR PA    P+      KG   L PP   PP K   P +G  +   
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 254 -SKRDPLCPRRAEPCPRVPATPRRMS-----DPPLSTMPTAPGLRKPPCFRESASPSPEP 307
            +   P    +++  P +PATP   S       PL   P +P    PP  +    PSP  
Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS--APPSLQ--TLPSPPA 359

Query: 308 WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 367
             P     S  S  + AT          SF  SP   P + PPP                
Sbjct: 360 TPPSQATTSLGSPTLQAT---------HSFLPSPPLSPLATPPP--------------QA 396

Query: 368 PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQ--LPHLQRSP 417
           P   A+P L  PP  P  P L          P   P P+ P     HL ++P
Sbjct: 397 PPALALPPLQAPPSPPASPPLS---------PLATPSPQAPNALAVHLLQAP 439



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 63/238 (26%), Positives = 81/238 (34%), Gaps = 53/238 (22%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------ 239
           P SP           PP   PPP+  P        P+A    +  P   LP PP      
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541

Query: 240 ----PKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPAT---------PRRMSDP------ 280
               P   LP   LA    +  P+    A P  +VP +         PRR   P      
Sbjct: 542 APFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598

Query: 281 --PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 338
             P  T+  APG   PP  R  +S    P   GH + +TS+            ++L+ + 
Sbjct: 599 SGPRLTLALAPGPPPPPS-RSPSSTLSGPDLAGHSSSATSTP-----------EELRGYD 646

Query: 339 LSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR-PPALKLPVPEA 395
             P G   + PPP           AE      AA      PP+A R  P   LP P A
Sbjct: 647 SGPEGGAAASPPP----------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 15/141 (10%)

Query: 186 PDSPEPGRLEDALMHPPAYPP--PPVPTPRKPAFSDMPRAHS----FTSKGPGPLLPPPP 239
           P    P  L   L+  P  PP  P +  PR+P       + S      +  PGP  PPPP
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPP 615

Query: 240 ---PKHGL--PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR-- 292
              P   L  PD+   +  +   P   R  +  P   A      D  L+    A   R  
Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675

Query: 293 KPPCFRESASPSPEPWTPGHG 313
            PP     A  +P PW P  G
Sbjct: 676 APPLAFRGAPGAPLPWPPATG 696



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 47/189 (24%), Positives = 57/189 (30%), Gaps = 42/189 (22%)

Query: 227 TSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRA---------------------- 264
           T + PG   PPPP       V  AA    R PL  R                        
Sbjct: 26  TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85

Query: 265 ---EPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAA 321
               P  R PA+ R    PP     T+PG   P      AS +  P   G      S+  
Sbjct: 86  SSRNPASRPPASGRGERAPPAKN--TSPG---PVSSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 322 IMATATSRNCDKLKSFHLSPR----GPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLF 377
            +A   +    K  +     R    GP    P P  A + +     E   PR A      
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPA------ 193

Query: 378 VPPVAPRPP 386
            P   PRPP
Sbjct: 194 -PSARPRPP 201


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 66/243 (27%), Positives = 88/243 (36%), Gaps = 38/243 (15%)

Query: 201 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-----PDVGLAAEDSK 255
           PP  PP    T  KP FS       F    PG    PP P+        PDVG     SK
Sbjct: 126 PPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG-----SK 179

Query: 256 RDPLCPRRAEPCPRVPATPRRMSDPPLST-MPTAPGLRKPPCFRESASPSPEPWTPGHGA 314
            D + P        VP+TPR +   P +   P  PG  + P    S  P+P P+ PG+  
Sbjct: 180 PDSIPPP-------VPSTPRPIQSSPHNRGSPPVPGGPRQP----SPGPTPPPF-PGNRG 227

Query: 315 CSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAA-M 373
            +    +I  +  S +              P S  PP+P    + L      PP      
Sbjct: 228 TALGGGSIRQSPLSSSS-------------PFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274

Query: 374 PGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQ 433
           P +    V P PP    P   +  RP+   +   P  P  +  PP      S + E PR 
Sbjct: 275 PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334

Query: 434 PSQ 436
           P +
Sbjct: 335 PQR 337



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/316 (25%), Positives = 101/316 (31%), Gaps = 63/316 (19%)

Query: 166 PYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHS 225
           P P+        +   + + P  P+ G   D++       PPPVP+  +P  S      S
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI-------PPPVPSTPRPIQSSPHNRGS 203

Query: 226 FTSKG------PGPLLPPPPPKHGLP---------DVGLAAEDSKRDPL--CPRRA---E 265
               G      PGP  PP P   G            +  ++  S R PL   P RA   +
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263

Query: 266 PCPRVPATPRRMS--------DPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 317
           P P  P    R S         PP +  P  P   +P    ++  P P P  PG      
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323

Query: 318 SSAAIMATAT--SRNCDKLKSF-------HLSPRGPPTSEPPPVPANKPKFLKIAEEDPP 368
           SS+    T     RN     S           P  PP SE PP P   P         PP
Sbjct: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383

Query: 369 -------REAAMP---------GLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPH 412
                     A+P         G+  P   PRPP   LP     A     P P       
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP---LPPDRPSAGAPPPPPPSTSIRNG 440

Query: 413 LQRSPPDGQSFRSFSF 428
            Q SP + +    F F
Sbjct: 441 FQDSPCEDEWESRFYF 456



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/142 (29%), Positives = 47/142 (33%), Gaps = 38/142 (26%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P  P PGR       P   PPPPV  P  P  S             GPL PPPP      
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDP--PGRS-------------GPLPPPPPVSRN-- 388

Query: 246 DVGLAAEDSKRDPLCPRRA-----EPCPRVPATPRRMS----DPPLSTMPTAPGLRKPPC 296
             G  +      P  P R+        PR P  P R S     PP  +     G +  PC
Sbjct: 389 --GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPC 446

Query: 297 FRE----------SASPSPEPW 308
             E          S  P PEP+
Sbjct: 447 EDEWESRFYFHPISDLPPPEPY 468


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 66/243 (27%), Positives = 88/243 (36%), Gaps = 38/243 (15%)

Query: 201 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-----PDVGLAAEDSK 255
           PP  PP    T  KP FS       F    PG    PP P+        PDVG     SK
Sbjct: 126 PPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG-----SK 179

Query: 256 RDPLCPRRAEPCPRVPATPRRMSDPPLST-MPTAPGLRKPPCFRESASPSPEPWTPGHGA 314
            D + P        VP+TPR +   P +   P  PG  + P    S  P+P P+ PG+  
Sbjct: 180 PDSIPPP-------VPSTPRPIQSSPHNRGSPPVPGGPRQP----SPGPTPPPF-PGNRG 227

Query: 315 CSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAA-M 373
            +    +I  +  S +              P S  PP+P    + L      PP      
Sbjct: 228 TALGGGSIRQSPLSSSS-------------PFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274

Query: 374 PGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQ 433
           P +    V P PP    P   +  RP+   +   P  P  +  PP      S + E PR 
Sbjct: 275 PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334

Query: 434 PSQ 436
           P +
Sbjct: 335 PQR 337



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/316 (25%), Positives = 101/316 (31%), Gaps = 63/316 (19%)

Query: 166 PYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHS 225
           P P+        +   + + P  P+ G   D++       PPPVP+  +P  S      S
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI-------PPPVPSTPRPIQSSPHNRGS 203

Query: 226 FTSKG------PGPLLPPPPPKHGLP---------DVGLAAEDSKRDPL--CPRRA---E 265
               G      PGP  PP P   G            +  ++  S R PL   P RA   +
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263

Query: 266 PCPRVPATPRRMS--------DPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 317
           P P  P    R S         PP +  P  P   +P    ++  P P P  PG      
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323

Query: 318 SSAAIMATAT--SRNCDKLKSF-------HLSPRGPPTSEPPPVPANKPKFLKIAEEDPP 368
           SS+    T     RN     S           P  PP SE PP P   P         PP
Sbjct: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383

Query: 369 -------REAAMP---------GLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPH 412
                     A+P         G+  P   PRPP   LP     A     P P       
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP---LPPDRPSAGAPPPPPPSTSIRNG 440

Query: 413 LQRSPPDGQSFRSFSF 428
            Q SP + +    F F
Sbjct: 441 FQDSPCEDEWESRFYF 456



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/142 (29%), Positives = 47/142 (33%), Gaps = 38/142 (26%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
           P  P PGR       P   PPPPV  P  P  S             GPL PPPP      
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDP--PGRS-------------GPLPPPPPVSRN-- 388

Query: 246 DVGLAAEDSKRDPLCPRRA-----EPCPRVPATPRRMS----DPPLSTMPTAPGLRKPPC 296
             G  +      P  P R+        PR P  P R S     PP  +     G +  PC
Sbjct: 389 --GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPC 446

Query: 297 FRE----------SASPSPEPW 308
             E          S  P PEP+
Sbjct: 447 EDEWESRFYFHPISDLPPPEPY 468


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 64/260 (24%)

Query: 182 SYLEPDSPEPGRLED-------ALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPL 234
           S L P+SP+P  L         +++ P    P P P P KPA                 +
Sbjct: 139 SVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA----------------SV 182

Query: 235 LPPPPPKHGLPDVGLAAEDSKRDPL-CPRRAEPCPRVPATPR-RMSDPPLSTMPTAPGLR 292
             P PPK  +P      E  K  P+  P   +P P  P + +  +S+P        P   
Sbjct: 183 SSPEPPK-SVP----VCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETL 237

Query: 293 KPPCFRESASP----SPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSE 348
            PP      SP    SPEPW P   A   S  +   T+              PR P  SE
Sbjct: 238 GPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP------------EPRKPSPSE 285

Query: 349 PP----PVPANKPKFLKIAEEDPPREAAMPGLFV--PPVAPR-----PPALKLPVPEAMA 397
            P    P PA  P      E   P  A  PG +   PP +PR     P A   P   A  
Sbjct: 286 SPEPWKPFPAVSP------EPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKP 339

Query: 398 RPAVLPRPEKPQLPHLQRSP 417
            P+V P P KP +P +   P
Sbjct: 340 APSVSPGPWKP-IPSVSPGP 358



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 68/260 (26%), Positives = 89/260 (34%), Gaps = 32/260 (12%)

Query: 201 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPL- 259
           P    PP   +P  P  +  P        GP P   P   K        + E  K  P  
Sbjct: 234 PETLGPPSASSPESPVLAASPEPW-----GPSPAASPESRKSARTT---SPEPRKPSPSE 285

Query: 260 CPRRAEPCPRVPATPRRMSDP--PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 317
            P   +P P V   PRR +    P S  P  PG  +P  ++ + S S  PW P   A S 
Sbjct: 286 SPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRP--WKSNPSASSGPWKPAKPAPSV 343

Query: 318 S----------SAAIMATATSRNCDKLKSFHLSP---RGPPTSEPPPVPANKPKFLKIAE 364
           S          S        S +    KS  +SP   + PP S P    +  P+  K A 
Sbjct: 344 SPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPAS-PESWKSGPPELRKTAP 402

Query: 365 EDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQ-LPHLQRSPPDGQSF 423
              P         VPPV+P       P+   +  PA  P   KP   P L +  PD +  
Sbjct: 403 TLSPEHWKA----VPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKT 458

Query: 424 RSFSFEKPRQPSQADTGGDD 443
              S + P     +  G  D
Sbjct: 459 SPASLDFPESQKSSRGGSPD 478



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 57/236 (24%), Positives = 89/236 (37%), Gaps = 47/236 (19%)

Query: 228 SKGPGPLLPPPPPKH-----------GLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 276
           +K   P+  PP P+H            +P + +  +      L P   +P P  P  P++
Sbjct: 100 NKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQ-KLGSVLSPESPKPTPLTPLEPQK 158

Query: 277 MSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKS 336
               P S +  +P L+ P        PSPEP  P         A++ +    ++    +S
Sbjct: 159 ----PGSVV--SPELQTP-------LPSPEPSKP---------ASVSSPEPPKSVPVCES 196

Query: 337 FHLSP-RGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVA--PRPPALKLPVP 393
             L+P   P   +P PV     K   ++   P +++  P    PP A  P  P L     
Sbjct: 197 QKLAPVPSPEPQKPAPVSPESVK-ATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPE 255

Query: 394 EAMARPAVLPRPEK--------PQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGG 441
                PA  P   K        P+ P    SP   + F + S E PR+P+ A + G
Sbjct: 256 PWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPE-PRRPAPAVSPG 310


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 66/220 (30%), Positives = 82/220 (37%), Gaps = 44/220 (20%)

Query: 188 SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDV 247
           SP PG  +D    PP  P PP PT      S  P     TS+ PGP  PP  P       
Sbjct: 728 SPSPGG-DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVP------- 779

Query: 248 GLAAEDSKRDPLCPRRAE-PCPRVP----ATPRRMSDPPLSTMPTAPGLRKPPCFRESAS 302
                   R+PL P+ +  P P VP      P R+S  P  TMPT           +S +
Sbjct: 780 -------PREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTT----------QSFA 822

Query: 303 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH--LSPRGPPTSEPPPVPANKPKFL 360
             P+  TP         A        R+  K+ S H  L P  P   E         +FL
Sbjct: 823 SDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLE------RYQRFL 876

Query: 361 KIAEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARP 399
           + A+  + P    +P L  PP  P P A     P A  RP
Sbjct: 877 REAQSPEEPTPLPVPLLLPPPSTPAPAA-----PTATVRP 911



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 72/304 (23%), Positives = 102/304 (33%), Gaps = 51/304 (16%)

Query: 139 PLDTSD------SSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPG 192
           P+D  D      S+S      G V++P              Y+   ED   L  D    G
Sbjct: 490 PMDPPDLLSVELSTSRPPQHLGGVKKPT-------------YDPVSEDQDPLSSDFKRLG 536

Query: 193 RLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAE 252
             +  L        P    P   A        +    G  P++P   P    P +   A 
Sbjct: 537 LRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPC--APSLAQLAM 594

Query: 253 DSKRDPLCPRRAEPCPRVP--ATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTP 310
           D+     C    E  P+ P  A PR +   P+      P L  PP + + A    +    
Sbjct: 595 DA-----CSLLDETPPQSPTRALPRPLHPTPVVDWDARP-LPPPPAYDDVAQDEDD---- 644

Query: 311 GHGACSTSSAAIMATATSRNCDKLKSFHLSP---RGPPTSE-----PPPVPANKPKFLKI 362
               CS +S  + A   +       ++   P   R PP  E     PP      P   + 
Sbjct: 645 -FEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQT 703

Query: 363 AEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPR---PEKPQLPHLQRSP- 417
           AE     ++  M  L  P  +P P     P P    +P V PR   P +P  PH+Q SP 
Sbjct: 704 AEIFQALQQECMRQLQAPAGSPAPS----PSPGGDDKPQVPPRVPIPPRPTRPHVQLSPA 759

Query: 418 PDGQ 421
           P G+
Sbjct: 760 PPGE 763



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 63/289 (21%), Positives = 98/289 (33%), Gaps = 50/289 (17%)

Query: 202 PAYPPPPV-----PTPRKPAFSDMPRAH--------SFTSKGPGPLLPPPPPKHGLPDVG 248
           P +P P V     P P  PA+ D+ +          + T  G G    P  P  G  +  
Sbjct: 615 PLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGV---PAGPSQGQTNYA 671

Query: 249 LAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR--KPPCFRESASP--S 304
              E ++  P       P       P +    P S+  TA   +  +  C R+  +P  S
Sbjct: 672 FVPEQARPPP-------PLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGS 724

Query: 305 PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAE 364
           P P +P  G               R          +P G   +   P PA+ P+   +  
Sbjct: 725 PAP-SPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR---VPP 780

Query: 365 EDP--PREAAMPGLFVPP-VAPRPPALK------LPVPEAMARPAVLPRPEKPQLPHLQR 415
            +P  P+ +  P   VPP  +P PP L       +P  ++ A       P+  Q P  + 
Sbjct: 781 REPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRA 840

Query: 416 SP------PDGQSFRSFSF----EKPRQPSQADTGGDDSDEDYEKVPLP 454
            P       DG+   S  +    E+P    +      ++    E  PLP
Sbjct: 841 GPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLP 889



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 5/67 (7%)

Query: 186 PDSPEPGRLEDALMHPPAYPPPPVPT----PRKPAFSDMPRAHSFTSKGPGPLLPPPPPK 241
           P+ P P  +   L+ PP+ P P  PT    P   A  D     S  +  PG   PPP   
Sbjct: 882 PEEPTPLPVP-LLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRAT 940

Query: 242 HGLPDVG 248
             LP  G
Sbjct: 941 ARLPQRG 947



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 46/177 (25%), Positives = 62/177 (35%), Gaps = 31/177 (17%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPP--VPTPRKPAFSDMPRAHSFTSK---GPGPLLPPPP 239
           EP SP+  R    L+ P + P PP    +P K     MP   SF S        ++  P 
Sbjct: 782 EPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGK----TMPTTQSFASDPKYATPQVIQAPG 837

Query: 240 PKHGLPDVGLAAEDSKRDP-----LCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP 294
           P+ G P +     D K+       L P R     R     R    P   T    P L  P
Sbjct: 838 PRAG-PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPP 896

Query: 295 PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP 351
           P     ++P+P        A  T++   M  A     D   +F  +   P    PPP
Sbjct: 897 P-----STPAP--------AAPTATVRPMPQAA---LDPKANFSTNNSNPGARPPPP 937


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
           sapiens]
          Length = 1086

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 66/220 (30%), Positives = 82/220 (37%), Gaps = 44/220 (20%)

Query: 188 SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDV 247
           SP PG  +D    PP  P PP PT      S  P     TS+ PGP  PP  P       
Sbjct: 806 SPSPGG-DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVP------- 857

Query: 248 GLAAEDSKRDPLCPRRAE-PCPRVP----ATPRRMSDPPLSTMPTAPGLRKPPCFRESAS 302
                   R+PL P+ +  P P VP      P R+S  P  TMPT           +S +
Sbjct: 858 -------PREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTT----------QSFA 900

Query: 303 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH--LSPRGPPTSEPPPVPANKPKFL 360
             P+  TP         A        R+  K+ S H  L P  P   E         +FL
Sbjct: 901 SDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLE------RYQRFL 954

Query: 361 KIAEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARP 399
           + A+  + P    +P L  PP  P P A     P A  RP
Sbjct: 955 REAQSPEEPTPLPVPLLLPPPSTPAPAA-----PTATVRP 989



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 74/306 (24%), Positives = 104/306 (33%), Gaps = 40/306 (13%)

Query: 139 PLDTSD------SSSDTDSFYGAVER--PVDISLSPYPTDNEDYEHDDEDDSYLEPDSPE 190
           P+D  D      S+S      G V+R  P       + T    Y+   ED   L  D   
Sbjct: 553 PMDPPDLLSVELSTSRPPQHLGGVKREPPPRPPQPAFFTQKPTYDPVSEDQDPLSSDFKR 612

Query: 191 PGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLA 250
            G  +  L        P    P   A        +    G  P++P   P    P +   
Sbjct: 613 LGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPC--APSLAQL 670

Query: 251 AEDSKRDPLCPRRAEPCPRVP--ATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPW 308
           A D+     C    E  P+ P  A PR +   P+      P L  PP + + A    +  
Sbjct: 671 AMDA-----CSLLDETPPQSPTRALPRPLHPTPVVDWDARP-LPPPPAYDDVAQDEDD-- 722

Query: 309 TPGHGACSTSSAAIMATATSRNCDKLKSFHLSP---RGPPTSE-----PPPVPANKPKFL 360
                 CS +S  + A   +       ++   P   R PP  E     PP      P   
Sbjct: 723 ---FEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSA 779

Query: 361 KIAEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPR---PEKPQLPHLQRS 416
           + AE     ++  M  L  P  +P P     P P    +P V PR   P +P  PH+Q S
Sbjct: 780 QTAEIFQALQQECMRQLQAPAGSPAPS----PSPGGDDKPQVPPRVPIPPRPTRPHVQLS 835

Query: 417 P-PDGQ 421
           P P G+
Sbjct: 836 PAPPGE 841



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 63/289 (21%), Positives = 98/289 (33%), Gaps = 50/289 (17%)

Query: 202 PAYPPPPV-----PTPRKPAFSDMPRAH--------SFTSKGPGPLLPPPPPKHGLPDVG 248
           P +P P V     P P  PA+ D+ +          + T  G G    P  P  G  +  
Sbjct: 693 PLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGV---PAGPSQGQTNYA 749

Query: 249 LAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR--KPPCFRESASP--S 304
              E ++  P       P       P +    P S+  TA   +  +  C R+  +P  S
Sbjct: 750 FVPEQARPPP-------PLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGS 802

Query: 305 PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAE 364
           P P +P  G               R          +P G   +   P PA+ P+   +  
Sbjct: 803 PAP-SPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR---VPP 858

Query: 365 EDP--PREAAMPGLFVPP-VAPRPPALK------LPVPEAMARPAVLPRPEKPQLPHLQR 415
            +P  P+ +  P   VPP  +P PP L       +P  ++ A       P+  Q P  + 
Sbjct: 859 REPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRA 918

Query: 416 SP------PDGQSFRSFSF----EKPRQPSQADTGGDDSDEDYEKVPLP 454
            P       DG+   S  +    E+P    +      ++    E  PLP
Sbjct: 919 GPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLP 967



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 5/67 (7%)

Query: 186  PDSPEPGRLEDALMHPPAYPPPPVPT----PRKPAFSDMPRAHSFTSKGPGPLLPPPPPK 241
            P+ P P  +   L+ PP+ P P  PT    P   A  D     S  +  PG   PPP   
Sbjct: 960  PEEPTPLPVP-LLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRAT 1018

Query: 242  HGLPDVG 248
              LP  G
Sbjct: 1019 ARLPQRG 1025



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 46/177 (25%), Positives = 62/177 (35%), Gaps = 31/177 (17%)

Query: 185  EPDSPEPGRLEDALMHPPAYPPPP--VPTPRKPAFSDMPRAHSFTSK---GPGPLLPPPP 239
            EP SP+  R    L+ P + P PP    +P K     MP   SF S        ++  P 
Sbjct: 860  EPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGK----TMPTTQSFASDPKYATPQVIQAPG 915

Query: 240  PKHGLPDVGLAAEDSKRDP-----LCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP 294
            P+ G P +     D K+       L P R     R     R    P   T    P L  P
Sbjct: 916  PRAG-PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPP 974

Query: 295  PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP 351
            P     ++P+P        A  T++   M  A     D   +F  +   P    PPP
Sbjct: 975  P-----STPAP--------AAPTATVRPMPQAA---LDPKANFSTNNSNPGARPPPP 1015


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 69/253 (27%), Positives = 85/253 (33%), Gaps = 53/253 (20%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 244
           +P  P P   +     PP  PPP  P P +P     P              PPPPP    
Sbjct: 57  KPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQ---------QPPPPP---- 103

Query: 245 PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPS 304
                  +DS + P+  +   P P V + P   S  P +T PT+     PP     + P 
Sbjct: 104 -------QDSSK-PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA---PP----GSGPG 148

Query: 305 PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANK-------P 357
           P P TP     S    A   T  S            P  PP + P P P  K       P
Sbjct: 149 PTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGP 207

Query: 358 KFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLP-----H 412
           K  K+     P+    PGL  P   P+PP           R    PR  +   P     H
Sbjct: 208 KGGKM--PGGPKPGGGPGLSTPGGHPKPP----------HRGGGEPRGGRQHHPPYHQQH 255

Query: 413 LQRSPPDGQSFRS 425
            Q  PP G   RS
Sbjct: 256 HQGPPPGGPGGRS 268



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 47/194 (24%), Positives = 59/194 (30%), Gaps = 19/194 (9%)

Query: 238 PPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCF 297
           PPP  GL        +  R P+ P   +  P+ P  P           P  P  ++PP  
Sbjct: 34  PPPGMGL--------NQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH 85

Query: 298 RESASPSP----EPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPP--- 350
           +    P P    +P  P   +     A     A         S    P  PPTS  P   
Sbjct: 86  QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145

Query: 351 ---PVPANKPKFLKIAEEDPPREAAMPGL-FVPPVAPRPPALKLPVPEAMARPAVLPRPE 406
              P P   P         PP      G+   PP A  PP     VP     P   P P 
Sbjct: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPG 205

Query: 407 KPQLPHLQRSPPDG 420
            P+   +   P  G
Sbjct: 206 GPKGGKMPGGPKPG 219


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 62/258 (24%), Positives = 106/258 (41%), Gaps = 34/258 (13%)

Query: 185   EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFS-----DMPRAHSFTSKGPGPLLP--- 236
             +P++P P ++ +A          PVP P+KP        ++P+A     K P  + P   
Sbjct: 10517 KPEAPPP-KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE 10575

Query: 237   -PPP-----PKHGLPDVGLAAEDSKRD-------PLCPRRAEPCPRVPATPRRMSDPPLS 283
              PPP     PK  +P+  + A   K+        P  P+   P  +VP  P +  + P +
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635

Query: 284   TMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK-----SFH 338
              +P  P +  P      A P P+P +P            +    +   ++ +        
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694

Query: 339   LSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR----PPALKLPVP 393
             + P+ P P  + P V A KP+   +   + P+E  +P   VP V P+    PPA    VP
Sbjct: 10695 VPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEV-VPEKKVPLVVPKKPEAPPAKVPEVP 10753

Query: 394   EAMARPAVLPRPEKPQLP 411
             + +     +  P+KP++P
Sbjct: 10754 KEVVPEKKVAVPKKPEVP 10771



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 61/254 (24%), Positives = 90/254 (35%), Gaps = 43/254 (16%)

Query: 178   DEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFS--DMPRAHSFTSKGPGPLL 235
             +E + + +P +P  G      + PP  PP  V   ++P     ++P+      K   P  
Sbjct: 10428 EEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE 10487

Query: 236   PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 295
             P  PP   +P+V           L P+   P  +VP  P +  + P   +P AP    P 
Sbjct: 10488 PRVPPTK-VPEV-----------LPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP- 10534

Query: 296   CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP------ 349
                E   P P P  P             A    +  + +      P  PP   P      
Sbjct: 10535 ---EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP---KPESPPPEVPEAPKEV 10588

Query: 350   ------PPVPANKPKFLKIAEEDPPREAAMPGLFVP---PVAPRPPALKLP------VPE 394
                   P  P  KP+   +   + P+E  +P   VP   P  P  P  K+P      VPE
Sbjct: 10589 VPEKKVPAAPPKKPEVTPVKVPEAPKEV-VPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE 10647

Query: 395   AMARPAVLPRPEKP 408
                  A+ P+PE P
Sbjct: 10648 KKVPEAIPPKPESP 10661



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 66/285 (23%), Positives = 102/285 (35%), Gaps = 46/285 (16%)

Query: 157   ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 216
             E+ V  ++ P P        ++ ++  LE    E     +    P    PP  P P K  
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEK-- 10704

Query: 217   FSDMPRAHSFTSKGP--GPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPR--VP- 271
                  +A +  +K P   P+  P  PK  +P+  +     K+    P +    P+  VP 
Sbjct: 10705 -----KAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPE 10759

Query: 272   ---ATPRRMSDPP--LSTMPTAPGLRKPPCF---RESASPSPEPWTPGHGACSTSSAAIM 323
                A P++   PP  +  +P  P L + P       + SP PE +            A  
Sbjct: 10760 KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIA-- 10817

Query: 324   ATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKF--------LKIAEEDPPRE----- 370
                     ++ K   ++    P   PP VP    K         +K  E  PP+E     
Sbjct: 10818 -------PEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870

Query: 371   -AAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPR---PEKPQLP 411
                 P L   P  P P   K  V E + +   +P+   PEKPQ+P
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP 10915



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 82/338 (24%), Positives = 115/338 (34%), Gaps = 65/338 (19%)

Query: 172   EDYEHDDEDDSYLEPDSPEPGRLEDA---LMHP----PAYPPPPVPTPRKPAFSDMPRAH 224
             E+YE  +E D Y E +  E  R E+    +  P    P  P P  P P KP     P A 
Sbjct: 9757  EEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPK---APPAK 9813

Query: 225   SFTSKGPGPLLPPPPPKHGLPDVGLAAEDSK-------RDPLCPRR----AEPCPRVPAT 273
                   P   +P P PK   P      E+ K       R  +  R      EP  +VP  
Sbjct: 9814  VLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK 9873

Query: 274   PRRM---SDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN 330
             P+R+      P+     AP +R P   +E     PE          T     +       
Sbjct: 9874  PKRVVAEEKVPVPRKEVAPPVRVPEVPKEL---EPEE-VAFEEEVVTHVEEYLVEEEEEY 9929

Query: 331   CDKLKSFHLS--------------PRGPPTSEPPPVPANK---------PKFLKIAEEDP 367
               + + F                 PR P   E  PVP  K         P+  K  EE  
Sbjct: 9930  IHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKV 9989

Query: 368   ----PREAAMPGLFVPPVAPRP-PALKLPVP---EAMARPAVLPRPEKPQLPHLQRSPPD 419
                 P++   P   VP V  +P P  K+PVP   +  A PA +P   K  +P  +   P 
Sbjct: 9990  PVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA 10049

Query: 420   GQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSV 457
              +   +   + P  P +         E+ +  P+P  V
Sbjct: 10050 PKKVEAPPAKVPEVPKKL------IPEEKKPTPVPKKV 10081



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 63/263 (23%), Positives = 90/263 (34%), Gaps = 30/263 (11%)

Query: 185   EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG- 243
             +P+SP P   E      P    P  P P+KP  + +    +     P   +P PPPK   
Sbjct: 10573 KPESPPPEVPEAPKEVVPEKKVPAAP-PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631

Query: 244   -----LPDVGLAAEDSKRDP--LCPRRAEPCPRVPATPRRMS--DPPLSTMPTAPGLRKP 294
                  +P+V   A   K+ P  + P+   P P V   P  ++  +PP   +        P
Sbjct: 10632 VPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPP 10691

Query: 295   PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL----SPRGPPTSEPP 350
                     P PE   P   A       +      +     K   L     P  PP   P 
Sbjct: 10692 QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE 10751

Query: 351   P----VPANKPKFLKIAEEDP------PREAAM---PGLFVPPVAPRPPALKLPVPEAMA 397
                  VP  K    K  E  P      P++  +   P + VP  A  PP      PE +A
Sbjct: 10752 VPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIA 10811

Query: 398   -RPAVLPRPEKPQLPHLQRSPPD 419
                 + P  EKP +P  +   P+
Sbjct: 10812 PEEEIAPEEEKP-VPVAEEEEPE 10833



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 52/208 (25%), Positives = 74/208 (35%), Gaps = 23/208 (11%)

Query: 186   PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 245
             P  PEP ++ +     P  PPPP P P K    +         K   P  P  P K  L 
Sbjct: 10863 PKEPEPEKVIEKPKLKPR-PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT 10921

Query: 246   DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSP 305
              + +   + K   L P R +P P+     + +             LRK P   E   P  
Sbjct: 10922 PLKVPGGEKKVRKLLPER-KPEPKEEVVLKSV-------------LRKRP---EEEEPKV 10964

Query: 306   EPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKF-LKIAE 364
             EP             A+      +  ++++   ++ R     EP  VP  KP   L   E
Sbjct: 10965 EP----KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPE 11020

Query: 365   EDPPREAAMPGLFVPPVAPRPPALKLPV 392
               P  EA +  +  PPV P P  +  PV
Sbjct: 11021 PKPKPEAEVKTIKPPPVEPEPTPIAAPV 11048



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 53/241 (21%), Positives = 78/241 (32%), Gaps = 54/241 (22%)

Query: 185   EPDSPEPGRLEDA----------LMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPL 234
             EP+ P P   E+           ++  P  PPP  P P K    + P+          P 
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVI--EKPKLK--------PR 10880

Query: 235   LPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP 294
              PPPPP     DV        ++ +   +A P  +VP  P+      L+ +    G +K 
Sbjct: 10881 PPPPPPAPPKEDV--------KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932

Query: 295   PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPA 354
                     P P+               + +    R              P   EP   P 
Sbjct: 10933 RKLLPERKPEPK-----------EEVVLKSVLRKR--------------PEEEEPKVEPK 10967

Query: 355   NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAV-LPRPEKPQLPHL 413
                K  K A  +PP    +  + VP V  R   +  P      +PA+ LP PE    P  
Sbjct: 10968 KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA 11027

Query: 414   Q 414
             +
Sbjct: 11028 E 11028



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 59/276 (21%), Positives = 98/276 (35%), Gaps = 55/276 (19%)

Query: 170   DNEDYEHDDEDDSYLEPDSPE-PGRLEDALMHPPAYPPPPVPTPRK----PA-FSDMPRA 223
             + E+Y H++E+    E   P  P ++ +    P      PVP P+K    PA   ++P+ 
Sbjct: 9925  EEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKK 9984

Query: 224   HSFT-------SKGPGPLLPPPPPKHGLPDVGLAAEDSK-------RDPLCPRRAEPCPR 269
                         + P P   P  PK  +P+  +     K       + P  P++  P  +
Sbjct: 9985  PEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044

Query: 270   VPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSR 329
             VP    +  + P + +P  P    P    E   P+P P                      
Sbjct: 10045 VPVPAPKKVEAPPAKVPEVPKKLIP----EEKKPTPVP---------------------- 10078

Query: 330   NCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKI--AEEDPPREAAMPGLFVPPVAPRPPA 387
                  K     P+ P   EP PVP   P+  ++   EE  P E  +P      V P    
Sbjct: 10079 ----KKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE--EEEVLPEEEE 10132

Query: 388   LKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSF 423
             +     E +     +P PE+ ++P  +   P+ + F
Sbjct: 10133 VLPEEEEVLPEEEEIP-PEEEEVPPEEEYVPEEEEF 10167



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 44/220 (20%), Positives = 73/220 (33%), Gaps = 31/220 (14%)

Query: 157  ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDAL--MHPPAYPPPPVPTPRK 214
            E    +S+S Y  +  + E + E   Y   + PE   +E+ L  +       P   T R+
Sbjct: 9499 EEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQ 9558

Query: 215  PAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATP 274
                 +        + P P   P  PK  +P+  + A   K++ + P      P+VP  P
Sbjct: 9559 EKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPP------PKVPEEP 9612

Query: 275  RRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKL 334
            ++            P  + PP   +   P P   T  H   +     ++A          
Sbjct: 9613 KK----------PVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVT-------- 9654

Query: 335  KSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMP 374
                     PP +  P  P       K+ +  P RE   P
Sbjct: 9655 -----KKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPP 9689



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 7/85 (8%)

Query: 335  KSFHLSPRGPPT-SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVP 393
            K   L P+ P    EPPP    +     + E+  P          PP  P  P  K PVP
Sbjct: 9560 KKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEP--KKPVP 9617

Query: 394  EAMARPAVL----PRPEKPQLPHLQ 414
            E    P V+    P P K    H+Q
Sbjct: 9618 EKKVPPKVIKMEEPLPAKVTERHMQ 9642



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 42/211 (19%), Positives = 77/211 (36%), Gaps = 30/211 (14%)

Query: 109  FFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYP 168
            FF++ +EEE    +  +++EI     ++ + +  S             E+P    ++P P
Sbjct: 9248 FFASHTEEEVSVTVPEVQKEIV---TEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVP 9304

Query: 169  TDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSD-MPRAHSFT 227
               +      +     +   PE  +        PA PP     P+KP   + +P   +  
Sbjct: 9305 IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKK 9364

Query: 228  SKGPGPLLPP--------------------PPPKHGLPDVGLAAEDSKRDPLCPRRAE-- 265
             + P   +P                     PPP   +P++       +R P+ PR+ E  
Sbjct: 9365 KEAPPAKVPEVQKGVVTEEKITIVTQREESPPP--AVPEIPKKKVPEERKPV-PRKEEEV 9421

Query: 266  -PCPRVPATPRRMSDPPLSTMPTAPGLRKPP 295
             P P+VPA P++        +P     + PP
Sbjct: 9422 PPPPKVPALPKKPVPEEKVAVPVPVAKKAPP 9452


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 56/208 (26%), Positives = 75/208 (36%), Gaps = 56/208 (26%)

Query: 201 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLL-------------------PPPPP- 240
           PP  PPPP P P  P  S  P      S  PGPL                    PPPPP 
Sbjct: 176 PPTPPPPPPPLP-PPLPSSSPIKTPLVSP-PGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233

Query: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTA--PGLRKPPCFR 298
              LP   + ++ + +  L P    P P           PPL  +P    PGL+  P   
Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIP-----------PPLPLLPPCGYPGLKAEPASP 282

Query: 299 ESAS---PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 355
              +   P+P P  P + +CS  ++             L +  L      +  PPP+P  
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRAS-------------LPAPPLPGVNSSSETPPPLPPK 329

Query: 356 KPKFLKIAEEDPPREAAMPGLFVPPVAP 383
            P F     + PP++A    L  PP  P
Sbjct: 330 SPSF-----QAPPQKAGAQALPAPPAPP 352



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 42/134 (31%), Positives = 49/134 (36%), Gaps = 19/134 (14%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPG--------PLLP 236
           EP SP     +DA   PPA PPPP+P    P  S  PRA       PG        P LP
Sbjct: 278 EPASPA----QDA-QEPPA-PPPPLP----PYASCSPRASLPAPPLPGVNSSSETPPPLP 327

Query: 237 PPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPC 296
           P  P    P     A+     P  P  ++P  +     R  +       P AP  R P  
Sbjct: 328 PKSPSFQAPPQKAGAQALPAPP-APPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTT 386

Query: 297 FRESASPSPEPWTP 310
              S S     WTP
Sbjct: 387 ELSSKSQQATAWTP 400



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 56/211 (26%), Positives = 65/211 (30%), Gaps = 71/211 (33%)

Query: 232 GPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL 291
           GPL+PP  P+ G       A          R A P P VPA       PP  T P  P  
Sbjct: 142 GPLIPPASPRLGNTSEAHGAA---------RTAPPRPNVPA-------PPPPTPPPPPPP 185

Query: 292 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP 351
             PP       PS  P                          +K+  +SP GP T    P
Sbjct: 186 LPPPL------PSSSP--------------------------IKTPLVSPPGPLTKGNLP 213

Query: 352 VPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA------MARPAVLPRP 405
           V A            PP   A P     P  P PP    P+P A        +P + P  
Sbjct: 214 VVA------------PPVPCAPP-----PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLH 256

Query: 406 EKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQ 436
             P  P L   PP G          P Q +Q
Sbjct: 257 LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQ 287



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 60/238 (25%), Positives = 77/238 (32%), Gaps = 62/238 (26%)

Query: 199 MHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDP 258
           M  P  PPPP+P P                  P PL  PPPP    P V         D 
Sbjct: 1   MPVPPPPPPPLPPP------------------PPPLGAPPPPPPSAPPV-------STDT 35

Query: 259 LCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPW----TPGHGA 314
              RRA+P  R            L+ +     LRK     + ++P  E        G G+
Sbjct: 36  SSLRRADPKGR---------SALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGS 86

Query: 315 CSTSSAA--------------IMATATSRNCDKLK------SFHLSPRGP-PTSEPPPVP 353
            +T  A+              ++  A  R+    K      S   SPR P  T   P +P
Sbjct: 87  ANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIP 146

Query: 354 ANKPKFLKIAEEDPPREAAMPGLFV---PPVAPRPPALKLPVPEAMARPAVLPRPEKP 408
              P+    +E       A P   V   PP  P PP   LP P   + P   P    P
Sbjct: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 91/392 (23%), Positives = 142/392 (36%), Gaps = 40/392 (10%)

Query: 62  KSSTSASPQGAFSLSGYNR---VMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEER 118
           +SS   SP  A + S  ++   V ++A++       P K    +K+ R    S + E +R
Sbjct: 53  RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS---NKRQREKVASDTEEADR 109

Query: 119 KSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDI-----SLSPYPTDNED 173
            S      +EI   +   +   ++SDS S  D        P DI     S SP     +D
Sbjct: 110 TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---GSSDPKDIDQDNRSTSPSIPSPQD 166

Query: 174 YEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGP 233
            E D +  +  +    +P  L+      PA    P  TP+ P     P A +   +G  P
Sbjct: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP 225

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRK 293
                P +   P   +     ++ P    +  P P  P  P     PPL  +  + G   
Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--PHPSPHPPLQPLTGSAG--- 280

Query: 294 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP---P 350
               + SA    +P  P HG       ++ A    ++    + F L P+      P    
Sbjct: 281 ----QPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 334

Query: 351 PVPANKPKFLKIA-------EEDPPREAAMPG--LFVPPVAPRP--PALKLPVPEAMARP 399
           P  A     L++         + PPRE  +P   L +P + P P  P  +LP P+A   P
Sbjct: 335 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394

Query: 400 AVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKP 431
             L  P    +      PP  +   S S   P
Sbjct: 395 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/269 (23%), Positives = 86/269 (31%), Gaps = 61/269 (22%)

Query: 201 PPAYPPPPVPTPRKPA-------------FSDMPRAHSFTSKGP-----GPLL--PPPPP 240
           PP+  PPP P+P  P                  P  H     GP     GPLL  P PP 
Sbjct: 257 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316

Query: 241 KHGLP---------------------DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSD 279
             GLP                      + L A  S      P R +P P  P     +  
Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 376

Query: 280 PPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL 339
           PP + +P  P  +        + PSP           + +A +      +    L + H 
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSP----------FSMNANLPPPPALKPLSSLSTHHP 426

Query: 340 SPRGPPT------SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV- 392
               PP       S+P P    +P  L  ++  PP  A+ P   +  VAP+PP  + P  
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486

Query: 393 ---PEAMARPAVLPRPEKPQLPHLQRSPP 418
              P  +  P        P  P     PP
Sbjct: 487 PGGPPPITPPTCPSTSTPPAGPGTSAQPP 515



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 11/190 (5%)

Query: 189 PEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-PDV 247
           P P  +   L  PPA  P    +   P  +  P         P P  P  PP  GL    
Sbjct: 400 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQ 457

Query: 248 GLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEP 307
            L    +   P    +  P P     P     PP  T PT P    PP     A P    
Sbjct: 458 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP-----AGPGTSA 512

Query: 308 WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 367
             P  GA ++  +    ++      ++K   L     P S PPP  +  P+   +   D 
Sbjct: 513 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV---DT 569

Query: 368 PREAAMPGLF 377
           P  A+    F
Sbjct: 570 PSHASQSARF 579



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 22/112 (19%)

Query: 344 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
           PP +   P P   P    +  +  P  +  P         +P A   PVP    + A   
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN--------QPQAPTAPVPHTHIQQAPAL 252

Query: 404 RPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG--GDDSDEDYEKVPL 453
            P++P  PH    PP   S        P  P Q  TG  G  S   + + PL
Sbjct: 253 HPQRPPSPH----PPPHPS--------PHPPLQPLTGSAGQPSAPSHAQPPL 292


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 91/392 (23%), Positives = 142/392 (36%), Gaps = 40/392 (10%)

Query: 62  KSSTSASPQGAFSLSGYNR---VMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEER 118
           +SS   SP  A + S  ++   V ++A++       P K    +K+ R    S + E +R
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS---NKRQREKVASDTEEADR 663

Query: 119 KSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDI-----SLSPYPTDNED 173
            S      +EI   +   +   ++SDS S  D        P DI     S SP     +D
Sbjct: 664 TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---GSSDPKDIDQDNRSTSPSIPSPQD 720

Query: 174 YEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGP 233
            E D +  +  +    +P  L+      PA    P  TP+ P     P A +   +G  P
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP 779

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRK 293
                P +   P   +     ++ P    +  P P  P  P     PPL  +  + G   
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--PHPSPHPPLQPLTGSAG--- 834

Query: 294 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP---P 350
               + SA    +P  P HG       ++ A    ++    + F L P+      P    
Sbjct: 835 ----QPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 888

Query: 351 PVPANKPKFLKIA-------EEDPPREAAMPG--LFVPPVAPRP--PALKLPVPEAMARP 399
           P  A     L++         + PPRE  +P   L +P + P P  P  +LP P+A   P
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948

Query: 400 AVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKP 431
             L  P    +      PP  +   S S   P
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/269 (23%), Positives = 86/269 (31%), Gaps = 61/269 (22%)

Query: 201  PPAYPPPPVPTPRKPA-------------FSDMPRAHSFTSKGP-----GPLL--PPPPP 240
            PP+  PPP P+P  P                  P  H     GP     GPLL  P PP 
Sbjct: 811  PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 241  KHGLP---------------------DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSD 279
              GLP                      + L A  S      P R +P P  P     +  
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930

Query: 280  PPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL 339
            PP + +P  P  +        + PSP           + +A +      +    L + H 
Sbjct: 931  PPTTPIPQLPAPQAHKHPPHLSGPSP----------FSMNANLPPPPALKPLSSLSTHHP 980

Query: 340  SPRGPPT------SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV- 392
                PP       S+P P    +P  L  ++  PP  A+ P   +  VAP+PP  + P  
Sbjct: 981  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040

Query: 393  ---PEAMARPAVLPRPEKPQLPHLQRSPP 418
               P  +  P        P  P     PP
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 11/190 (5%)

Query: 189  PEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-PDV 247
            P P  +   L  PPA  P    +   P  +  P         P P  P  PP  GL    
Sbjct: 954  PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQ 1011

Query: 248  GLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEP 307
             L    +   P    +  P P     P     PP  T PT P    PP     A P    
Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP-----AGPGTSA 1066

Query: 308  WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 367
              P  GA ++  +    ++      ++K   L     P S PPP  +  P+   +   D 
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV---DT 1123

Query: 368  PREAAMPGLF 377
            P  A+    F
Sbjct: 1124 PSHASQSARF 1133



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 22/112 (19%)

Query: 344 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
           PP +   P P   P    +  +  P  +  P         +P A   PVP    + A   
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN--------QPQAPTAPVPHTHIQQAPAL 806

Query: 404 RPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG--GDDSDEDYEKVPL 453
            P++P  PH    PP   S        P  P Q  TG  G  S   + + PL
Sbjct: 807 HPQRPPSPH----PPPHPS--------PHPPLQPLTGSAGQPSAPSHAQPPL 846


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 91/392 (23%), Positives = 142/392 (36%), Gaps = 40/392 (10%)

Query: 62  KSSTSASPQGAFSLSGYNR---VMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEER 118
           +SS   SP  A + S  ++   V ++A++       P K    +K+ R    S + E +R
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS---NKRQREKVASDTEEADR 663

Query: 119 KSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDI-----SLSPYPTDNED 173
            S      +EI   +   +   ++SDS S  D        P DI     S SP     +D
Sbjct: 664 TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---GSSDPKDIDQDNRSTSPSIPSPQD 720

Query: 174 YEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGP 233
            E D +  +  +    +P  L+      PA    P  TP+ P     P A +   +G  P
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP 779

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRK 293
                P +   P   +     ++ P    +  P P  P  P     PPL  +  + G   
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--PHPSPHPPLQPLTGSAG--- 834

Query: 294 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP---P 350
               + SA    +P  P HG       ++ A    ++    + F L P+      P    
Sbjct: 835 ----QPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 888

Query: 351 PVPANKPKFLKIA-------EEDPPREAAMPG--LFVPPVAPRP--PALKLPVPEAMARP 399
           P  A     L++         + PPRE  +P   L +P + P P  P  +LP P+A   P
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948

Query: 400 AVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKP 431
             L  P    +      PP  +   S S   P
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/269 (23%), Positives = 86/269 (31%), Gaps = 61/269 (22%)

Query: 201  PPAYPPPPVPTPRKPA-------------FSDMPRAHSFTSKGP-----GPLL--PPPPP 240
            PP+  PPP P+P  P                  P  H     GP     GPLL  P PP 
Sbjct: 811  PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 241  KHGLP---------------------DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSD 279
              GLP                      + L A  S      P R +P P  P     +  
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930

Query: 280  PPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL 339
            PP + +P  P  +        + PSP           + +A +      +    L + H 
Sbjct: 931  PPTTPIPQLPAPQAHKHPPHLSGPSP----------FSMNANLPPPPALKPLSSLSTHHP 980

Query: 340  SPRGPPT------SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV- 392
                PP       S+P P    +P  L  ++  PP  A+ P   +  VAP+PP  + P  
Sbjct: 981  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040

Query: 393  ---PEAMARPAVLPRPEKPQLPHLQRSPP 418
               P  +  P        P  P     PP
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 11/190 (5%)

Query: 189  PEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-PDV 247
            P P  +   L  PPA  P    +   P  +  P         P P  P  PP  GL    
Sbjct: 954  PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQ 1011

Query: 248  GLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEP 307
             L    +   P    +  P P     P     PP  T PT P    PP     A P    
Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP-----AGPGTSA 1066

Query: 308  WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 367
              P  GA ++  +    ++      ++K   L     P S PPP  +  P+   +   D 
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV---DT 1123

Query: 368  PREAAMPGLF 377
            P  A+    F
Sbjct: 1124 PSHASQSARF 1133



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 22/112 (19%)

Query: 344 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 403
           PP +   P P   P    +  +  P  +  P         +P A   PVP    + A   
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN--------QPQAPTAPVPHTHIQQAPAL 806

Query: 404 RPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG--GDDSDEDYEKVPL 453
            P++P  PH    PP   S        P  P Q  TG  G  S   + + PL
Sbjct: 807 HPQRPPSPH----PPPHPS--------PHPPLQPLTGSAGQPSAPSHAQPPL 846


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)

Query: 157 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 216
           + P   ++   PT  ++        +   P  P P   ++     P  P  P PT  K  
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 286

Query: 217 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 276
                ++   T K P P  P  P           A  + ++P      EP P  P  P  
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 335

Query: 277 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 320
            +  P  T      PTAP    P   +E A           +  P P TP   A +T+ +
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395

Query: 321 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 379
           A   T         KS   +P+ P PT+   P P    +      + P            
Sbjct: 396 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 454

Query: 380 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 438
           P  P P   K P P     PA   P+   P  P  + +P   +     + EKP   +  +
Sbjct: 455 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 513

Query: 439 TGGDDSDEDYEKVP 452
                 +E     P
Sbjct: 514 LAPTTPEEPTPTTP 527



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)

Query: 166 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 218
           P PT  E+      E+ +   P+ P P   + A  + P  P P  P      TP++PA +
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565

Query: 219 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 275
                   T KG  P  L  P P     P     A  + ++P      +P P  P  T  
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 276 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 335
                P  T P  P    P     +    P P TP   A    +       TS   DK  
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 683

Query: 336 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 390
               +P  P    PT+   P P    K      E PP   +   +  P     P  + K 
Sbjct: 684 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 738

Query: 391 P---VPEAMARP---AVLPRPEKPQLP 411
           P    PE  A P   A+   P++P +P
Sbjct: 739 PDESTPELSAEPTPKALENSPKEPGVP 765



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 244
           EP    P          PA   P  P P  P  +        T   P  L P  P K   
Sbjct: 449 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 508

Query: 245 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 298
                 A  +  +P      EP P  P  A P    +P    P    PT P    P   +
Sbjct: 509 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568

Query: 299 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 341
           E+A  +P+           P TP   A    +       TS  CDK        +   +P
Sbjct: 569 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628

Query: 342 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 386
           + P PT+   P P       P  LK      P++ A P    P             P P 
Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 687

Query: 387 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 446
             K   P     PA  P   K   P    +PP   S  S +    ++P+      D+S  
Sbjct: 688 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 744

Query: 447 DYEKVPLPNSV 457
           +    P P ++
Sbjct: 745 ELSAEPTPKAL 755



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 288
           +L  P PK         AE + + P      EP P  P      TP+  +   + + PT 
Sbjct: 193 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243

Query: 289 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 338
           P    P      P   +  +P+    P P TP   A +T+      T  S      +   
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303

Query: 339 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 395
            +P+ P PT+  EP P    +P      E  P  +   P     P  P P A K P P  
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 360

Query: 396 MARPAVLPRPEKPQLPHLQRSP 417
              PA  P   K   P   + P
Sbjct: 361 PKEPA--PTTPKEPAPTTTKEP 380



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)

Query: 187 DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 240
           D P P   ++     P  P P   TP+KPA +        TS+   P     P      P
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739

Query: 241 KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 291
               P++       A E+S ++P  P    P    P +  T + + ++  L T P     
Sbjct: 740 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 798

Query: 292 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 349
             P   +E+A+ + E  T      +T+      T   T      LK+  L+P+   T + 
Sbjct: 799 AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 857

Query: 350 PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 407
                  NKP+     E   P++ A       P  P+ P      P +  +P  +PR  K
Sbjct: 858 ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 911

Query: 408 PQ 409
           P+
Sbjct: 912 PK 913



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)

Query: 286 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 344
           PT+  L KP    E+ +  P   TP     +T       T        +KS   +P+ P 
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248

Query: 345 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 387
                             T EP P    +P      E  P    + P     P  P P  
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 305

Query: 388 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
            K P P     PA      P P  P+ P      P   + +  +   P++P+
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)

Query: 157 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 216
           + P   ++   PT  ++        +   P  P P   ++     P  P  P PT  K  
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 327

Query: 217 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 276
                ++   T K P P  P  P           A  + ++P      EP P  P  P  
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 376

Query: 277 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 320
            +  P  T      PTAP    P   +E A           +  P P TP   A +T+ +
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436

Query: 321 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 379
           A   T         KS   +P+ P PT+   P P    +      + P            
Sbjct: 437 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 495

Query: 380 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 438
           P  P P   K P P     PA   P+   P  P  + +P   +     + EKP   +  +
Sbjct: 496 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 554

Query: 439 TGGDDSDEDYEKVP 452
                 +E     P
Sbjct: 555 LAPTTPEEPTPTTP 568



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)

Query: 166 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 218
           P PT  E+      E+ +   P+ P P   + A  + P  P P  P      TP++PA +
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606

Query: 219 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 275
                   T KG  P  L  P P     P     A  + ++P      +P P  P  T  
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 276 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 335
                P  T P  P    P     +    P P TP   A    +       TS   DK  
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 724

Query: 336 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 390
               +P  P    PT+   P P    K      E PP   +   +  P     P  + K 
Sbjct: 725 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 779

Query: 391 P---VPEAMARP---AVLPRPEKPQLP 411
           P    PE  A P   A+   P++P +P
Sbjct: 780 PDESTPELSAEPTPKALENSPKEPGVP 806



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 244
           EP    P          PA   P  P P  P  +        T   P  L P  P K   
Sbjct: 490 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 549

Query: 245 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 298
                 A  +  +P      EP P  P  A P    +P    P    PT P    P   +
Sbjct: 550 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609

Query: 299 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 341
           E+A  +P+           P TP   A    +       TS  CDK        +   +P
Sbjct: 610 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669

Query: 342 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 386
           + P PT+   P P       P  LK      P++ A P    P             P P 
Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 728

Query: 387 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 446
             K   P     PA  P   K   P    +PP   S  S +    ++P+      D+S  
Sbjct: 729 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 785

Query: 447 DYEKVPLPNSV 457
           +    P P ++
Sbjct: 786 ELSAEPTPKAL 796



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 288
           +L  P PK         AE + + P      EP P  P      TP+  +   + + PT 
Sbjct: 234 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284

Query: 289 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 338
           P    P      P   +  +P+    P P TP   A +T+      T  S      +   
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344

Query: 339 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 395
            +P+ P PT+  EP P    +P      E  P  +   P     P  P P A K P P  
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 401

Query: 396 MARPAVLPRPEKPQLPHLQRSP 417
              PA  P   K   P   + P
Sbjct: 402 PKEPA--PTTPKEPAPTTTKEP 421



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)

Query: 187 DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 240
           D P P   ++     P  P P   TP+KPA +        TS+   P     P      P
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780

Query: 241 KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 291
               P++       A E+S ++P  P    P    P +  T + + ++  L T P     
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 839

Query: 292 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 349
             P   +E+A+ + E  T      +T+      T   T      LK+  L+P+   T + 
Sbjct: 840 AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 898

Query: 350 PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 407
                  NKP+     E   P++ A       P  P+ P      P +  +P  +PR  K
Sbjct: 899 ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 952

Query: 408 PQ 409
           P+
Sbjct: 953 PK 954



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)

Query: 286 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 344
           PT+  L KP    E+ +  P   TP     +T       T        +KS   +P+ P 
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289

Query: 345 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 387
                             T EP P    +P      E  P    + P     P  P P  
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 346

Query: 388 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
            K P P     PA      P P  P+ P      P   + +  +   P++P+
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)

Query: 157 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 216
           + P   ++   PT  ++        +   P  P P   ++     P  P  P PT  K  
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 379

Query: 217 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 276
                ++   T K P P  P  P           A  + ++P      EP P  P  P  
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 428

Query: 277 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 320
            +  P  T      PTAP    P   +E A           +  P P TP   A +T+ +
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488

Query: 321 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 379
           A   T         KS   +P+ P PT+   P P    +      + P            
Sbjct: 489 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547

Query: 380 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 438
           P  P P   K P P     PA   P+   P  P  + +P   +     + EKP   +  +
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 606

Query: 439 TGGDDSDEDYEKVP 452
                 +E     P
Sbjct: 607 LAPTTPEEPTPTTP 620



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)

Query: 166 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 218
           P PT  E+      E+ +   P+ P P   + A  + P  P P  P      TP++PA +
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658

Query: 219 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 275
                   T KG  P  L  P P     P     A  + ++P      +P P  P  T  
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 276 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 335
                P  T P  P    P     +    P P TP   A    +       TS   DK  
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 776

Query: 336 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 390
               +P  P    PT+   P P    K      E PP   +   +  P     P  + K 
Sbjct: 777 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 831

Query: 391 P---VPEAMARP---AVLPRPEKPQLP 411
           P    PE  A P   A+   P++P +P
Sbjct: 832 PDESTPELSAEPTPKALENSPKEPGVP 858



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 244
           EP    P          PA   P  P P  P  +        T   P  L P  P K   
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 601

Query: 245 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 298
                 A  +  +P      EP P  P  A P    +P    P    PT P    P   +
Sbjct: 602 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661

Query: 299 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 341
           E+A  +P+           P TP   A    +       TS  CDK        +   +P
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721

Query: 342 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 386
           + P PT+   P P       P  LK      P++ A P    P             P P 
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 780

Query: 387 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 446
             K   P     PA  P   K   P    +PP   S  S +    ++P+      D+S  
Sbjct: 781 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 837

Query: 447 DYEKVPLPNSV 457
           +    P P ++
Sbjct: 838 ELSAEPTPKAL 848



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 288
           +L  P PK         AE + + P      EP P  P      TP+  +   + + PT 
Sbjct: 286 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336

Query: 289 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 338
           P    P      P   +  +P+    P P TP   A +T+      T  S      +   
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396

Query: 339 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 395
            +P+ P PT+  EP P    +P      E  P  +   P     P  P P A K P P  
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 453

Query: 396 MARPAVLPRPEKPQLPHLQRSP 417
              PA  P   K   P   + P
Sbjct: 454 PKEPA--PTTPKEPAPTTTKEP 473



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)

Query: 187  DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 240
            D P P   ++     P  P P   TP+KPA +        TS+   P     P      P
Sbjct: 775  DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832

Query: 241  KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 291
                P++       A E+S ++P  P    P    P +  T + + ++  L T P     
Sbjct: 833  DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 891

Query: 292  RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 349
              P   +E+A+ + E  T      +T+      T   T      LK+  L+P+   T + 
Sbjct: 892  AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 950

Query: 350  PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 407
                   NKP+     E   P++ A       P  P+ P      P +  +P  +PR  K
Sbjct: 951  ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 1004

Query: 408  PQ 409
            P+
Sbjct: 1005 PK 1006



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)

Query: 286 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 344
           PT+  L KP    E+ +  P   TP     +T       T        +KS   +P+ P 
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341

Query: 345 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 387
                             T EP P    +P      E  P    + P     P  P P  
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 398

Query: 388 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
            K P P     PA      P P  P+ P      P   + +  +   P++P+
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)

Query: 157 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 216
           + P   ++   PT  ++        +   P  P P   ++     P  P  P PT  K  
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 420

Query: 217 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 276
                ++   T K P P  P  P           A  + ++P      EP P  P  P  
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 469

Query: 277 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 320
            +  P  T      PTAP    P   +E A           +  P P TP   A +T+ +
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529

Query: 321 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 379
           A   T         KS   +P+ P PT+   P P    +      + P            
Sbjct: 530 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588

Query: 380 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 438
           P  P P   K P P     PA   P+   P  P  + +P   +     + EKP   +  +
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 647

Query: 439 TGGDDSDEDYEKVP 452
                 +E     P
Sbjct: 648 LAPTTPEEPTPTTP 661



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)

Query: 166 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 218
           P PT  E+      E+ +   P+ P P   + A  + P  P P  P      TP++PA +
Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699

Query: 219 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 275
                   T KG  P  L  P P     P     A  + ++P      +P P  P  T  
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 276 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 335
                P  T P  P    P     +    P P TP   A    +       TS   DK  
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 817

Query: 336 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 390
               +P  P    PT+   P P    K      E PP   +   +  P     P  + K 
Sbjct: 818 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 872

Query: 391 P---VPEAMARP---AVLPRPEKPQLP 411
           P    PE  A P   A+   P++P +P
Sbjct: 873 PDESTPELSAEPTPKALENSPKEPGVP 899



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)

Query: 185 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 244
           EP    P          PA   P  P P  P  +        T   P  L P  P K   
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 642

Query: 245 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 298
                 A  +  +P      EP P  P  A P    +P    P    PT P    P   +
Sbjct: 643 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702

Query: 299 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 341
           E+A  +P+           P TP   A    +       TS  CDK        +   +P
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762

Query: 342 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 386
           + P PT+   P P       P  LK      P++ A P    P             P P 
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 821

Query: 387 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 446
             K   P     PA  P   K   P    +PP   S  S +    ++P+      D+S  
Sbjct: 822 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 878

Query: 447 DYEKVPLPNSV 457
           +    P P ++
Sbjct: 879 ELSAEPTPKAL 889



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)

Query: 234 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 288
           +L  P PK         AE + + P      EP P  P      TP+  +   + + PT 
Sbjct: 327 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377

Query: 289 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 338
           P    P      P   +  +P+    P P TP   A +T+      T  S      +   
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437

Query: 339 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 395
            +P+ P PT+  EP P    +P      E  P  +   P     P  P P A K P P  
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 494

Query: 396 MARPAVLPRPEKPQLPHLQRSP 417
              PA  P   K   P   + P
Sbjct: 495 PKEPA--PTTPKEPAPTTTKEP 514



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)

Query: 187  DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 240
            D P P   ++     P  P P   TP+KPA +        TS+   P     P      P
Sbjct: 816  DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873

Query: 241  KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 291
                P++       A E+S ++P  P    P    P +  T + + ++  L T P     
Sbjct: 874  DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 932

Query: 292  RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 349
              P   +E+A+ + E  T      +T+      T   T      LK+  L+P+   T + 
Sbjct: 933  AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 991

Query: 350  PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 407
                   NKP+     E   P++ A       P  P+ P      P +  +P  +PR  K
Sbjct: 992  ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 1045

Query: 408  PQ 409
            P+
Sbjct: 1046 PK 1047



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)

Query: 286 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 344
           PT+  L KP    E+ +  P   TP     +T       T        +KS   +P+ P 
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382

Query: 345 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 387
                             T EP P    +P      E  P    + P     P  P P  
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 439

Query: 388 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 435
            K P P     PA      P P  P+ P      P   + +  +   P++P+
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,034,758
Number of Sequences: 37866
Number of extensions: 2166214
Number of successful extensions: 21055
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 223
Number of HSP's successfully gapped in prelim test: 1353
Number of HSP's that attempted gapping in prelim test: 11072
Number of HSP's gapped (non-prelim): 6486
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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