BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|16950655 cyclin D1 [Homo sapiens] (295 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|16950655 cyclin D1 [Homo sapiens] 590 e-169 gi|4502617 cyclin D2 [Homo sapiens] 358 2e-99 gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 295 3e-80 gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 201 6e-52 gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 124 8e-29 gi|4502613 cyclin A [Homo sapiens] 97 2e-20 gi|17318565 cyclin E2 [Homo sapiens] 93 2e-19 gi|161377472 cyclin A1 isoform c [Homo sapiens] 93 2e-19 gi|161377470 cyclin A1 isoform c [Homo sapiens] 93 2e-19 gi|161377468 cyclin A1 isoform b [Homo sapiens] 93 2e-19 gi|4502611 cyclin A1 isoform a [Homo sapiens] 93 2e-19 gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 90 3e-18 gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 90 3e-18 gi|14327896 cyclin B1 [Homo sapiens] 82 4e-16 gi|4757930 cyclin B2 [Homo sapiens] 78 1e-14 gi|153791755 cyclin domain containing [Homo sapiens] 69 4e-12 gi|209915556 cyclin D3 isoform 4 [Homo sapiens] 69 6e-12 gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 68 8e-12 gi|40805832 cyclin G1 [Homo sapiens] 65 5e-11 gi|4757934 cyclin G1 [Homo sapiens] 65 5e-11 gi|197276674 cyclin J isoform 1 [Homo sapiens] 64 1e-10 gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 64 2e-10 gi|118572588 cyclin F [Homo sapiens] 60 3e-09 gi|5802992 cyclin I [Homo sapiens] 59 7e-09 gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 50 2e-06 gi|40254889 cyclin J isoform 2 [Homo sapiens] 49 4e-06 gi|4502623 cyclin H [Homo sapiens] 49 5e-06 gi|197276676 cyclin J isoform 3 [Homo sapiens] 49 5e-06 gi|89886237 cyclin I family, member 2 [Homo sapiens] 48 1e-05 gi|94680985 cyclin J-like [Homo sapiens] 47 3e-05 >gi|16950655 cyclin D1 [Homo sapiens] Length = 295 Score = 590 bits (1520), Expect = e-169 Identities = 295/295 (100%), Positives = 295/295 (100%) Query: 1 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV 60 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV Sbjct: 1 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV 60 Query: 61 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT 120 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT Sbjct: 61 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT 120 Query: 121 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK 180 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK Sbjct: 121 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK 180 Query: 181 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD 240 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD Sbjct: 181 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD 240 Query: 241 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI Sbjct: 241 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 >gi|4502617 cyclin D2 [Homo sapiens] Length = 289 Score = 358 bits (920), Expect = 2e-99 Identities = 181/293 (61%), Positives = 224/293 (76%), Gaps = 6/293 (2%) Query: 4 QLLCCEVETIRRAYPDANLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVAT 62 +LLC EV+ +RRA D NLL +DRVL+ +L EE P SYFKCVQK++ P MR++VAT Sbjct: 2 ELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVAT 61 Query: 63 WMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAE 122 WMLEVCEEQKCEEEVFPLAMNYLDRFL+ P KS LQLLGA CMF+ASK+KET PLTAE Sbjct: 62 WMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAE 121 Query: 123 KLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHA 182 KLCIYTDNSI+P+ELL+ EL+++ KLKWNLAA+TPHDFIEH L K+P+ E +IRKHA Sbjct: 122 KLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHA 181 Query: 183 QTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPD 242 QTF+ALCATD KF PPSM+A GSV AA+ GL + L+ LT L+++ D D Sbjct: 182 QTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVD 241 Query: 243 CLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 CL+ACQEQIEA+L +SL+Q +Q+ + + E+E+D A TPTDVRD+D+ Sbjct: 242 CLKACQEQIEAVLLNSLQQYRQDQ-----RDGSKSEDELDQASTPTDVRDIDL 289 >gi|4502619 cyclin D3 isoform 2 [Homo sapiens] Length = 292 Score = 295 bits (755), Expect = 3e-80 Identities = 153/295 (51%), Positives = 200/295 (67%), Gaps = 7/295 (2%) Query: 4 QLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVA 61 +LLCCE RA PD LL D RVL+++L+ EE P SYF+CVQ+E+ P MRK++A Sbjct: 2 ELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLA 61 Query: 62 TWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTA 121 WMLEVCEEQ+CEEEVFPLAMNYLDR+LS P +K++LQLLGA CM +ASK++ET PLT Sbjct: 62 YWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTI 121 Query: 122 EKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKH 181 EKLCIYTD+++ P +L E+L++ KLKW+LAA+ HDF+ L ++ + + +++KH Sbjct: 122 EKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH 181 Query: 182 AQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDP 241 AQTF+ALCATD F PPSM+A GS+ AAVQGL S +S LT L+ + + Sbjct: 182 AQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEV 237 Query: 242 DCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 DCLRACQEQIEA L SLR+A Q + P + TPTDV + + Sbjct: 238 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292 >gi|209862835 cyclin D3 isoform 1 [Homo sapiens] Length = 211 Score = 201 bits (511), Expect = 6e-52 Identities = 104/215 (48%), Positives = 140/215 (65%), Gaps = 5/215 (2%) Query: 82 MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQME 141 MNYLDR+LS P +K++LQLLGA CM +ASK++ET PLT EKLCIYTD+++ P +L E Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60 Query: 142 LLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPS 201 +L++ KLKW+LAA+ HDF+ L ++ + + +++KHAQTF+ALCATD F PPS Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120 Query: 202 MVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQ 261 M+A GS+ AAVQGL S +S LT L+ + + DCLRACQEQIEA L SLR+ Sbjct: 121 MIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRESLRE 176 Query: 262 AQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 A Q + P + TPTDV + + Sbjct: 177 ASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211 >gi|209915553 cyclin D3 isoform 3 [Homo sapiens] Length = 220 Score = 124 bits (312), Expect = 8e-29 Identities = 68/156 (43%), Positives = 93/156 (59%), Gaps = 5/156 (3%) Query: 141 ELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPP 200 E+L++ KLKW+LAA+ HDF+ L ++ + + +++KHAQTF+ALCATD F PP Sbjct: 69 EVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPP 128 Query: 201 SMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLR 260 SM+A GS+ AAVQGL S +S LT L+ + + DCLRACQEQIEA L SLR Sbjct: 129 SMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 184 Query: 261 QAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 +A Q + P + TPTDV + + Sbjct: 185 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 220 Score = 68.2 bits (165), Expect = 8e-12 Identities = 35/65 (53%), Positives = 45/65 (69%), Gaps = 2/65 (3%) Query: 4 QLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVA 61 +LLCCE RA PD LL D RVL+++L+ EE P SYF+CVQ+E+ P MRK++A Sbjct: 2 ELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLA 61 Query: 62 TWMLE 66 WMLE Sbjct: 62 YWMLE 66 >gi|4502613 cyclin A [Homo sapiens] Length = 432 Score = 96.7 bits (239), Expect = 2e-20 Identities = 53/136 (38%), Positives = 82/136 (60%), Gaps = 2/136 (1%) Query: 35 EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94 E C P V Y K Q ++ SMR I+ W++EV EE K + E LA+NY+DRFLS V Sbjct: 190 EVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSV 248 Query: 95 KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAA 154 + +LQL+G M +ASK +E P + TD++ +++L+ME L++ L ++LAA Sbjct: 249 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAA 308 Query: 155 MTPHDFI-EHFLSKMP 169 T + F+ ++FL + P Sbjct: 309 PTVNQFLTQYFLHQQP 324 >gi|17318565 cyclin E2 [Homo sapiens] Length = 404 Score = 93.2 bits (230), Expect = 2e-19 Identities = 52/160 (32%), Positives = 90/160 (56%), Gaps = 3/160 (1%) Query: 31 MLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRF-L 89 MLK E +F+ + ++ P MR I+ W+LEVCE E F LA ++ DRF L Sbjct: 117 MLKKESRYVHD-KHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFML 175 Query: 90 SLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLK 149 + + + K+ LQL+G T +F+ASK++E ++ TD + E++L+MEL+++ LK Sbjct: 176 TQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALK 235 Query: 150 WNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-TFVAL 188 W L +T ++ FL + K ++ +++Q TF+ + Sbjct: 236 WELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQI 275 >gi|161377472 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 93.2 bits (230), Expect = 2e-19 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%) Query: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84 + + + + +AE P Y K Q ++ MR I+ W++EV EE K E LA+N+ Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 Query: 85 LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144 LDRFLS V + +LQL+G M +ASK +E P ++ TD++ +LL+ME LL Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204 + L ++L T + F+ +L + + + + A+ ++L D F+ PS++A Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 Query: 205 AGSVVAAVQGLN 216 A + A +N Sbjct: 345 AAAFCLANYTVN 356 >gi|161377470 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 93.2 bits (230), Expect = 2e-19 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%) Query: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84 + + + + +AE P Y K Q ++ MR I+ W++EV EE K E LA+N+ Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 Query: 85 LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144 LDRFLS V + +LQL+G M +ASK +E P ++ TD++ +LL+ME LL Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204 + L ++L T + F+ +L + + + + A+ ++L D F+ PS++A Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 Query: 205 AGSVVAAVQGLN 216 A + A +N Sbjct: 345 AAAFCLANYTVN 356 >gi|161377468 cyclin A1 isoform b [Homo sapiens] Length = 464 Score = 93.2 bits (230), Expect = 2e-19 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%) Query: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84 + + + + +AE P Y K Q ++ MR I+ W++EV EE K E LA+N+ Sbjct: 212 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 270 Query: 85 LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144 LDRFLS V + +LQL+G M +ASK +E P ++ TD++ +LL+ME LL Sbjct: 271 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 330 Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204 + L ++L T + F+ +L + + + + A+ ++L D F+ PS++A Sbjct: 331 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 387 Query: 205 AGSVVAAVQGLN 216 A + A +N Sbjct: 388 AAAFCLANYTVN 399 >gi|4502611 cyclin A1 isoform a [Homo sapiens] Length = 465 Score = 93.2 bits (230), Expect = 2e-19 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%) Query: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84 + + + + +AE P Y K Q ++ MR I+ W++EV EE K E LA+N+ Sbjct: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271 Query: 85 LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144 LDRFLS V + +LQL+G M +ASK +E P ++ TD++ +LL+ME LL Sbjct: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331 Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204 + L ++L T + F+ +L + + + + A+ ++L D F+ PS++A Sbjct: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388 Query: 205 AGSVVAAVQGLN 216 A + A +N Sbjct: 389 AAAFCLANYTVN 400 >gi|17318559 cyclin E1 isoform 1 [Homo sapiens] Length = 410 Score = 89.7 bits (221), Expect = 3e-18 Identities = 55/193 (28%), Positives = 103/193 (53%), Gaps = 11/193 (5%) Query: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVL-PSMRKIVATWMLEVCEEQKCEEEVFPLAMN 83 + V + ML E+T + + Q +L P MR I+ W++EVCE K E F LA + Sbjct: 114 EEVWKIMLNKEKTYLRDQHFLE--QHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQD 171 Query: 84 YLDRFLSL-EPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMEL 142 + DR+++ E V K+ LQL+G + +F+A+K++E P + TD + +E+L MEL Sbjct: 172 FFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMEL 231 Query: 143 LLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-------TFVALCATDVKF 195 +++ LKW L+ +T ++ ++ + ++ ++ ++ Q + LC DV Sbjct: 232 MIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDC 291 Query: 196 ISNPPSMVAAGSV 208 + P ++AA ++ Sbjct: 292 LEFPYGILAASAL 304 >gi|17318561 cyclin E1 isoform 2 [Homo sapiens] Length = 395 Score = 89.7 bits (221), Expect = 3e-18 Identities = 55/193 (28%), Positives = 103/193 (53%), Gaps = 11/193 (5%) Query: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVL-PSMRKIVATWMLEVCEEQKCEEEVFPLAMN 83 + V + ML E+T + + Q +L P MR I+ W++EVCE K E F LA + Sbjct: 99 EEVWKIMLNKEKTYLRDQHFLE--QHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQD 156 Query: 84 YLDRFLSL-EPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMEL 142 + DR+++ E V K+ LQL+G + +F+A+K++E P + TD + +E+L MEL Sbjct: 157 FFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMEL 216 Query: 143 LLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-------TFVALCATDVKF 195 +++ LKW L+ +T ++ ++ + ++ ++ ++ Q + LC DV Sbjct: 217 MIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDC 276 Query: 196 ISNPPSMVAAGSV 208 + P ++AA ++ Sbjct: 277 LEFPYGILAASAL 289 >gi|14327896 cyclin B1 [Homo sapiens] Length = 433 Score = 82.4 bits (202), Expect = 4e-16 Identities = 49/167 (29%), Positives = 86/167 (51%), Gaps = 4/167 (2%) Query: 50 KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109 +EV +MR I+ W+++V + + +E + ++ +DRF+ V K LQL+G T MF+ Sbjct: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254 Query: 110 ASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMP 169 ASK +E P TDN+ ++ QME+ ++ L + L P F+ SK+ Sbjct: 255 ASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRR-ASKIG 313 Query: 170 EAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLN 216 E + + + K+ + L D + PPS +AAG+ A++ L+ Sbjct: 314 EVDVEQHTLAKY---LMELTMLDYDMVHFPPSQIAAGAFCLALKILD 357 >gi|4757930 cyclin B2 [Homo sapiens] Length = 398 Score = 77.8 bits (190), Expect = 1e-14 Identities = 48/178 (26%), Positives = 87/178 (48%), Gaps = 4/178 (2%) Query: 50 KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109 +++ MR I+ W+++V + + +E + + +DRFL ++PV + +LQL+G T + + Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218 Query: 110 ASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMP 169 ASK +E E TDN+ ++ +ME L++ +LK+ L P F+ SK Sbjct: 219 ASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRR-ASKAG 277 Query: 170 EAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227 E + + + K+ + L D + PS VAA + + + L N YY Sbjct: 278 EVDVEQHTLAKY---LMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYY 332 >gi|153791755 cyclin domain containing [Homo sapiens] Length = 350 Score = 69.3 bits (168), Expect = 4e-12 Identities = 50/176 (28%), Positives = 79/176 (44%), Gaps = 4/176 (2%) Query: 49 QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108 Q +V R + +W++ V + E L +N LDRFL+ PV QLLG T + Sbjct: 125 QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLL 184 Query: 109 VASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKM 168 +A K E P ++L + ++L +E ++++KL + L A T F+EHF Sbjct: 185 IACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHAR 244 Query: 169 PEAEENKQIIRKHAQTF----VALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSP 220 EA + + AQ L D F S PS++A + A + L + P Sbjct: 245 VEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP 300 >gi|209915556 cyclin D3 isoform 4 [Homo sapiens] Length = 96 Score = 68.6 bits (166), Expect = 6e-12 Identities = 42/98 (42%), Positives = 53/98 (54%), Gaps = 5/98 (5%) Query: 199 PPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESS 258 PPSM+A GS+ AAVQGL S +S LT L+ + + DCLRACQEQIEA L S Sbjct: 3 PPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRES 58 Query: 259 LRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 LR+A Q + P + TPTDV + + Sbjct: 59 LREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 96 >gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo sapiens] Length = 307 Score = 68.2 bits (165), Expect = 8e-12 Identities = 37/107 (34%), Positives = 61/107 (57%) Query: 46 KCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGAT 105 + + + V P MR +V W+++V E + LA++ LD +LS V+ RLQLLG Sbjct: 97 RALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVA 156 Query: 106 CMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNL 152 C+FVA KM+E + LC+ + +S ELL+ E ++++L + L Sbjct: 157 CLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203 >gi|40805832 cyclin G1 [Homo sapiens] Length = 295 Score = 65.5 bits (158), Expect = 5e-11 Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 19/201 (9%) Query: 28 LRAMLKAEETCAPSVSYFKCVQK------EVLPSMRKIVATWMLEVCEEQKCEEEVFPLA 81 L A+L+ E C P V + ++ + +R +L + + + E F LA Sbjct: 17 LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76 Query: 82 MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKLCIYTDNSIRPEELL 138 +N LDRFLS V+ L +G +C ++A K E +PL + + I + +L+ Sbjct: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135 Query: 139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVAL------CATD 192 +ME +++ K+ W + A T F++ + S + +EN + R+++ F L C Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLL---QENLPLERRNSINFERLEAQLKACHCR 192 Query: 193 VKFISNPPSMVAAGSVVAAVQ 213 + F PS++A + +Q Sbjct: 193 IIFSKAKPSVLALSIIALEIQ 213 >gi|4757934 cyclin G1 [Homo sapiens] Length = 295 Score = 65.5 bits (158), Expect = 5e-11 Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 19/201 (9%) Query: 28 LRAMLKAEETCAPSVSYFKCVQK------EVLPSMRKIVATWMLEVCEEQKCEEEVFPLA 81 L A+L+ E C P V + ++ + +R +L + + + E F LA Sbjct: 17 LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76 Query: 82 MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKLCIYTDNSIRPEELL 138 +N LDRFLS V+ L +G +C ++A K E +PL + + I + +L+ Sbjct: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135 Query: 139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVAL------CATD 192 +ME +++ K+ W + A T F++ + S + +EN + R+++ F L C Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLL---QENLPLERRNSINFERLEAQLKACHCR 192 Query: 193 VKFISNPPSMVAAGSVVAAVQ 213 + F PS++A + +Q Sbjct: 193 IIFSKAKPSVLALSIIALEIQ 213 >gi|197276674 cyclin J isoform 1 [Homo sapiens] Length = 383 Score = 64.3 bits (155), Expect = 1e-10 Identities = 59/205 (28%), Positives = 100/205 (48%), Gaps = 29/205 (14%) Query: 80 LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132 LA+ LD F+ + +L L+ +C+ +ASK +E ++P E+L C+ N + Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121 Query: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK------------MPEAEENKQIIR 179 ++ LL MELLL+ +WNL T FIE++LS+ M E+ K + Sbjct: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMA 181 Query: 180 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 239 K+A F+ + D F++ PS+VAA V ++ L L SP +RLT + Sbjct: 182 KYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRL-SPTWPTRLHRLTAY------- 233 Query: 240 DPDCLRACQEQIEALLESSLRQAQQ 264 D L C E++ ++ +++A + Sbjct: 234 SWDFLVQCIERLLIAHDNDVKEANK 258 >gi|90669307 cyclin B3 isoform 3 [Homo sapiens] Length = 1395 Score = 63.5 bits (153), Expect = 2e-10 Identities = 45/179 (25%), Positives = 80/179 (44%), Gaps = 4/179 (2%) Query: 49 QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108 Q E+ MR I+ W++EV + E LA+ +D +L KK +LQLLGAT Sbjct: 1153 QIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFM 1212 Query: 109 VASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKM 168 +A+K +E + D++ + E+L ME+ ++N LK ++ + HFL + Sbjct: 1213 IAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAY----HFLRRY 1268 Query: 169 PEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227 ++ + + ++ S +AA S++ A+ L FL +Y Sbjct: 1269 ARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHY 1327 >gi|118572588 cyclin F [Homo sapiens] Length = 786 Score = 59.7 bits (143), Expect = 3e-09 Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 6/165 (3%) Query: 48 VQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCM 107 VQK + +MR I+ W++EV + L + +DR+L V + RLQLLG CM Sbjct: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360 Query: 108 FVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSK 167 + ++ LT + TDN+ + E+L++M +V+ L+ + T D+ E L+ Sbjct: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420 Query: 168 MPEAEENKQIIRKHAQTFVA-LCATDVKFISNPPSMVAAGSVVAA 211 +P ++ +H +F+ L + P+ +AA +++ A Sbjct: 421 VP-----VELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLA 460 >gi|5802992 cyclin I [Homo sapiens] Length = 377 Score = 58.5 bits (140), Expect = 7e-09 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 12/122 (9%) Query: 50 KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109 + V PS R V W+ ++ + E F LA + LDRFL+ L + +C F+ Sbjct: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97 Query: 110 ASKM---KETIP----LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIE 162 A+K E IP L + C E+L+ME ++++KL W+L TP DF+ Sbjct: 98 AAKTVEEDERIPVLKVLARDSFC-----GCSSSEILRMERIILDKLNWDLHTATPLDFLH 152 Query: 163 HF 164 F Sbjct: 153 IF 154 >gi|16306525 cyclin B3 isoform 1 [Homo sapiens] Length = 291 Score = 50.1 bits (118), Expect = 2e-06 Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 4/152 (2%) Query: 76 EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE 135 E LA+ +D +L KK +LQLLGAT +A+K +E + D++ + Sbjct: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135 Query: 136 ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKF 195 E+L ME+ ++N LK ++ + HFL + ++ + + + Sbjct: 136 EVLSMEINILNVLKCDINIPIAY----HFLRRYARCIHTNMKTLTLSRYICEMTLQEYHY 191 Query: 196 ISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227 + S +AA S++ A+ L FL +Y Sbjct: 192 VQEKASKLAAASLLLALYMKKLGYWVPFLEHY 223 >gi|40254889 cyclin J isoform 2 [Homo sapiens] Length = 372 Score = 49.3 bits (116), Expect = 4e-06 Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 40/205 (19%) Query: 80 LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132 LA+ LD F+ + +L L+ +C+ +ASK +E ++P E+L C+ N + Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121 Query: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK------------MPEAEENKQIIR 179 ++ LL MELLL+ +WNL T FIE++LS+ M E+ K + Sbjct: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMA 181 Query: 180 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 239 K+A F+ + S+ A + VA+ + + SP +RLT + Sbjct: 182 KYADYFLEV------------SLQVAAACVASSRIILRLSPTWPTRLHRLTAY------- 222 Query: 240 DPDCLRACQEQIEALLESSLRQAQQ 264 D L C E++ ++ +++A + Sbjct: 223 SWDFLVQCIERLLIAHDNDVKEANK 247 >gi|4502623 cyclin H [Homo sapiens] Length = 323 Score = 48.9 bits (115), Expect = 5e-06 Identities = 63/274 (22%), Positives = 115/274 (41%), Gaps = 32/274 (11%) Query: 11 ETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEE 70 E + R DAN R R A P+ F +E+ ++ K +LE C Sbjct: 17 EQLARLRADAN----RKFRCKAVANGKVLPNDPVFLEPHEEM--TLCKYYEKRLLEFCSV 70 Query: 71 QK--CEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYT 128 K V A Y RF V + +++ TC F+A K+ E + + + Sbjct: 71 FKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLR 130 Query: 129 DNSIRPE----ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAE---ENKQIIRKH 181 ++ + E ++L+ ELLL+ +L ++L P+ E FL + EN +I+RK Sbjct: 131 ESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKT 190 Query: 182 AQTFVALCATDVKFISNPPSMVAAGSVVAAVQ--GLNLRSPNNFLSYYRLTRFLSRVIKC 239 A F+ A ++ PS +A +++++ G+ + S +LS + Sbjct: 191 ADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMES------------YLSESLML 238 Query: 240 DPDCLRACQEQIEALLESSLRQAQQNMDPKAAEE 273 + R C Q+ +++ S+R + +P +EE Sbjct: 239 KEN--RTCLSQLLDIMK-SMRNLVKKYEPPRSEE 269 >gi|197276676 cyclin J isoform 3 [Homo sapiens] Length = 371 Score = 48.9 bits (115), Expect = 5e-06 Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 9/96 (9%) Query: 80 LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132 LA+ LD F+ + +L L+ +C+ +ASK +E ++P E+L C+ N + Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121 Query: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK 167 ++ LL MELLL+ +WNL T FIE++LS+ Sbjct: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157 >gi|89886237 cyclin I family, member 2 [Homo sapiens] Length = 369 Score = 47.8 bits (112), Expect = 1e-05 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 5/119 (4%) Query: 49 QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108 Q E+ + ++V W+L + + F LA+ R L VK+ L T + Sbjct: 143 QDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLR 201 Query: 109 VASKMKET---IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHF 164 +A+K+ E IP + Y + P ELL+MEL ++++L W+L TP DF+ F Sbjct: 202 LAAKVNEEEEFIPQVKDFTKHY-GSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIF 259 >gi|94680985 cyclin J-like [Homo sapiens] Length = 435 Score = 46.6 bits (109), Expect = 3e-05 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 21/145 (14%) Query: 131 SIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEEN-------------KQI 177 ++ +ELL ELLL+ WNL TP F++++L +++ K+ Sbjct: 169 TLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKEC 228 Query: 178 IRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVI 237 ++++A F+ + D F PS+VAA V A+ L L SP Y+ TR L R+ Sbjct: 229 LKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQL-SP-----YW--TRDLQRIS 280 Query: 238 KCDPDCLRACQEQIEALLESSLRQA 262 + L C E + + ++ L+ A Sbjct: 281 SYSLEHLSTCIEILLVVYDNVLKDA 305 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.132 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,171,253 Number of Sequences: 37866 Number of extensions: 469474 Number of successful extensions: 5633 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 55 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 5262 Number of HSP's gapped (non-prelim): 252 length of query: 295 length of database: 18,247,518 effective HSP length: 102 effective length of query: 193 effective length of database: 14,385,186 effective search space: 2776340898 effective search space used: 2776340898 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.