Guide to the Human Genome
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Search of human proteins with 16950655

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16950655 cyclin D1 [Homo sapiens]
         (295 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16950655 cyclin D1 [Homo sapiens]                                  590   e-169
gi|4502617 cyclin D2 [Homo sapiens]                                   358   2e-99
gi|4502619 cyclin D3 isoform 2 [Homo sapiens]                         295   3e-80
gi|209862835 cyclin D3 isoform 1 [Homo sapiens]                       201   6e-52
gi|209915553 cyclin D3 isoform 3 [Homo sapiens]                       124   8e-29
gi|4502613 cyclin A [Homo sapiens]                                     97   2e-20
gi|17318565 cyclin E2 [Homo sapiens]                                   93   2e-19
gi|161377472 cyclin A1 isoform c [Homo sapiens]                        93   2e-19
gi|161377470 cyclin A1 isoform c [Homo sapiens]                        93   2e-19
gi|161377468 cyclin A1 isoform b [Homo sapiens]                        93   2e-19
gi|4502611 cyclin A1 isoform a [Homo sapiens]                          93   2e-19
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                         90   3e-18
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                         90   3e-18
gi|14327896 cyclin B1 [Homo sapiens]                                   82   4e-16
gi|4757930 cyclin B2 [Homo sapiens]                                    78   1e-14
gi|153791755 cyclin domain containing [Homo sapiens]                   69   4e-12
gi|209915556 cyclin D3 isoform 4 [Homo sapiens]                        69   6e-12
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho...    68   8e-12
gi|40805832 cyclin G1 [Homo sapiens]                                   65   5e-11
gi|4757934 cyclin G1 [Homo sapiens]                                    65   5e-11
gi|197276674 cyclin J isoform 1 [Homo sapiens]                         64   1e-10
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         64   2e-10
gi|118572588 cyclin F [Homo sapiens]                                   60   3e-09
gi|5802992 cyclin I [Homo sapiens]                                     59   7e-09
gi|16306525 cyclin B3 isoform 1 [Homo sapiens]                         50   2e-06
gi|40254889 cyclin J isoform 2 [Homo sapiens]                          49   4e-06
gi|4502623 cyclin H [Homo sapiens]                                     49   5e-06
gi|197276676 cyclin J isoform 3 [Homo sapiens]                         49   5e-06
gi|89886237 cyclin I family, member 2 [Homo sapiens]                   48   1e-05
gi|94680985 cyclin J-like [Homo sapiens]                               47   3e-05

>gi|16950655 cyclin D1 [Homo sapiens]
          Length = 295

 Score =  590 bits (1520), Expect = e-169
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV 60
           MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV
Sbjct: 1   MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV 60

Query: 61  ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT 120
           ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT
Sbjct: 61  ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT 120

Query: 121 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK 180
           AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK
Sbjct: 121 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK 180

Query: 181 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD 240
           HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD
Sbjct: 181 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD 240

Query: 241 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
           PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
Sbjct: 241 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295


>gi|4502617 cyclin D2 [Homo sapiens]
          Length = 289

 Score =  358 bits (920), Expect = 2e-99
 Identities = 181/293 (61%), Positives = 224/293 (76%), Gaps = 6/293 (2%)

Query: 4   QLLCCEVETIRRAYPDANLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVAT 62
           +LLC EV+ +RRA  D NLL +DRVL+ +L  EE   P  SYFKCVQK++ P MR++VAT
Sbjct: 2   ELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVAT 61

Query: 63  WMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAE 122
           WMLEVCEEQKCEEEVFPLAMNYLDRFL+  P  KS LQLLGA CMF+ASK+KET PLTAE
Sbjct: 62  WMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAE 121

Query: 123 KLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHA 182
           KLCIYTDNSI+P+ELL+ EL+++ KLKWNLAA+TPHDFIEH L K+P+  E   +IRKHA
Sbjct: 122 KLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHA 181

Query: 183 QTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPD 242
           QTF+ALCATD KF   PPSM+A GSV AA+ GL      + L+   LT  L+++   D D
Sbjct: 182 QTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVD 241

Query: 243 CLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
           CL+ACQEQIEA+L +SL+Q +Q+       +  + E+E+D A TPTDVRD+D+
Sbjct: 242 CLKACQEQIEAVLLNSLQQYRQDQ-----RDGSKSEDELDQASTPTDVRDIDL 289


>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
          Length = 292

 Score =  295 bits (755), Expect = 3e-80
 Identities = 153/295 (51%), Positives = 200/295 (67%), Gaps = 7/295 (2%)

Query: 4   QLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVA 61
           +LLCCE      RA PD  LL D RVL+++L+ EE   P  SYF+CVQ+E+ P MRK++A
Sbjct: 2   ELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLA 61

Query: 62  TWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTA 121
            WMLEVCEEQ+CEEEVFPLAMNYLDR+LS  P +K++LQLLGA CM +ASK++ET PLT 
Sbjct: 62  YWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTI 121

Query: 122 EKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKH 181
           EKLCIYTD+++ P +L   E+L++ KLKW+LAA+  HDF+   L ++    + + +++KH
Sbjct: 122 EKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH 181

Query: 182 AQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDP 241
           AQTF+ALCATD  F   PPSM+A GS+ AAVQGL   S    +S   LT  L+ +   + 
Sbjct: 182 AQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEV 237

Query: 242 DCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
           DCLRACQEQIEA L  SLR+A Q +  P          +      TPTDV  + +
Sbjct: 238 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292


>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
          Length = 211

 Score =  201 bits (511), Expect = 6e-52
 Identities = 104/215 (48%), Positives = 140/215 (65%), Gaps = 5/215 (2%)

Query: 82  MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQME 141
           MNYLDR+LS  P +K++LQLLGA CM +ASK++ET PLT EKLCIYTD+++ P +L   E
Sbjct: 1   MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60

Query: 142 LLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPS 201
           +L++ KLKW+LAA+  HDF+   L ++    + + +++KHAQTF+ALCATD  F   PPS
Sbjct: 61  VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120

Query: 202 MVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQ 261
           M+A GS+ AAVQGL   S    +S   LT  L+ +   + DCLRACQEQIEA L  SLR+
Sbjct: 121 MIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRESLRE 176

Query: 262 AQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
           A Q +  P          +      TPTDV  + +
Sbjct: 177 ASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211


>gi|209915553 cyclin D3 isoform 3 [Homo sapiens]
          Length = 220

 Score =  124 bits (312), Expect = 8e-29
 Identities = 68/156 (43%), Positives = 93/156 (59%), Gaps = 5/156 (3%)

Query: 141 ELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPP 200
           E+L++ KLKW+LAA+  HDF+   L ++    + + +++KHAQTF+ALCATD  F   PP
Sbjct: 69  EVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPP 128

Query: 201 SMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLR 260
           SM+A GS+ AAVQGL   S    +S   LT  L+ +   + DCLRACQEQIEA L  SLR
Sbjct: 129 SMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 184

Query: 261 QAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
           +A Q +  P          +      TPTDV  + +
Sbjct: 185 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 220



 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 35/65 (53%), Positives = 45/65 (69%), Gaps = 2/65 (3%)

Query: 4  QLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVA 61
          +LLCCE      RA PD  LL D RVL+++L+ EE   P  SYF+CVQ+E+ P MRK++A
Sbjct: 2  ELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLA 61

Query: 62 TWMLE 66
           WMLE
Sbjct: 62 YWMLE 66


>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 53/136 (38%), Positives = 82/136 (60%), Gaps = 2/136 (1%)

Query: 35  EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94
           E  C P V Y K  Q ++  SMR I+  W++EV EE K + E   LA+NY+DRFLS   V
Sbjct: 190 EVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSV 248

Query: 95  KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAA 154
            + +LQL+G   M +ASK +E  P    +    TD++   +++L+ME L++  L ++LAA
Sbjct: 249 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAA 308

Query: 155 MTPHDFI-EHFLSKMP 169
            T + F+ ++FL + P
Sbjct: 309 PTVNQFLTQYFLHQQP 324


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 52/160 (32%), Positives = 90/160 (56%), Gaps = 3/160 (1%)

Query: 31  MLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRF-L 89
           MLK E        +F+ +  ++ P MR I+  W+LEVCE      E F LA ++ DRF L
Sbjct: 117 MLKKESRYVHD-KHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFML 175

Query: 90  SLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLK 149
           + + + K+ LQL+G T +F+ASK++E      ++    TD +   E++L+MEL+++  LK
Sbjct: 176 TQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALK 235

Query: 150 WNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-TFVAL 188
           W L  +T   ++  FL      +  K ++ +++Q TF+ +
Sbjct: 236 WELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQI 275


>gi|161377472 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%)

Query: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84
           + + + + +AE    P   Y K  Q ++   MR I+  W++EV EE K   E   LA+N+
Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227

Query: 85  LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144
           LDRFLS   V + +LQL+G   M +ASK +E  P   ++    TD++    +LL+ME LL
Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287

Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204
           +  L ++L   T + F+  +L +       + + +  A+  ++L   D  F+   PS++A
Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344

Query: 205 AGSVVAAVQGLN 216
           A +   A   +N
Sbjct: 345 AAAFCLANYTVN 356


>gi|161377470 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%)

Query: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84
           + + + + +AE    P   Y K  Q ++   MR I+  W++EV EE K   E   LA+N+
Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227

Query: 85  LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144
           LDRFLS   V + +LQL+G   M +ASK +E  P   ++    TD++    +LL+ME LL
Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287

Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204
           +  L ++L   T + F+  +L +       + + +  A+  ++L   D  F+   PS++A
Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344

Query: 205 AGSVVAAVQGLN 216
           A +   A   +N
Sbjct: 345 AAAFCLANYTVN 356


>gi|161377468 cyclin A1 isoform b [Homo sapiens]
          Length = 464

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%)

Query: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84
           + + + + +AE    P   Y K  Q ++   MR I+  W++EV EE K   E   LA+N+
Sbjct: 212 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 270

Query: 85  LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144
           LDRFLS   V + +LQL+G   M +ASK +E  P   ++    TD++    +LL+ME LL
Sbjct: 271 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 330

Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204
           +  L ++L   T + F+  +L +       + + +  A+  ++L   D  F+   PS++A
Sbjct: 331 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 387

Query: 205 AGSVVAAVQGLN 216
           A +   A   +N
Sbjct: 388 AAAFCLANYTVN 399


>gi|4502611 cyclin A1 isoform a [Homo sapiens]
          Length = 465

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%)

Query: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84
           + + + + +AE    P   Y K  Q ++   MR I+  W++EV EE K   E   LA+N+
Sbjct: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271

Query: 85  LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144
           LDRFLS   V + +LQL+G   M +ASK +E  P   ++    TD++    +LL+ME LL
Sbjct: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331

Query: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204
           +  L ++L   T + F+  +L +       + + +  A+  ++L   D  F+   PS++A
Sbjct: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388

Query: 205 AGSVVAAVQGLN 216
           A +   A   +N
Sbjct: 389 AAAFCLANYTVN 400


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 55/193 (28%), Positives = 103/193 (53%), Gaps = 11/193 (5%)

Query: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVL-PSMRKIVATWMLEVCEEQKCEEEVFPLAMN 83
           + V + ML  E+T      + +  Q  +L P MR I+  W++EVCE  K   E F LA +
Sbjct: 114 EEVWKIMLNKEKTYLRDQHFLE--QHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQD 171

Query: 84  YLDRFLSL-EPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMEL 142
           + DR+++  E V K+ LQL+G + +F+A+K++E  P    +    TD +   +E+L MEL
Sbjct: 172 FFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMEL 231

Query: 143 LLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-------TFVALCATDVKF 195
           +++  LKW L+ +T   ++  ++      + ++ ++ ++ Q         + LC  DV  
Sbjct: 232 MIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDC 291

Query: 196 ISNPPSMVAAGSV 208
           +  P  ++AA ++
Sbjct: 292 LEFPYGILAASAL 304


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 55/193 (28%), Positives = 103/193 (53%), Gaps = 11/193 (5%)

Query: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVL-PSMRKIVATWMLEVCEEQKCEEEVFPLAMN 83
           + V + ML  E+T      + +  Q  +L P MR I+  W++EVCE  K   E F LA +
Sbjct: 99  EEVWKIMLNKEKTYLRDQHFLE--QHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQD 156

Query: 84  YLDRFLSL-EPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMEL 142
           + DR+++  E V K+ LQL+G + +F+A+K++E  P    +    TD +   +E+L MEL
Sbjct: 157 FFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMEL 216

Query: 143 LLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-------TFVALCATDVKF 195
           +++  LKW L+ +T   ++  ++      + ++ ++ ++ Q         + LC  DV  
Sbjct: 217 MIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDC 276

Query: 196 ISNPPSMVAAGSV 208
           +  P  ++AA ++
Sbjct: 277 LEFPYGILAASAL 289


>gi|14327896 cyclin B1 [Homo sapiens]
          Length = 433

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 49/167 (29%), Positives = 86/167 (51%), Gaps = 4/167 (2%)

Query: 50  KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109
           +EV  +MR I+  W+++V  + +  +E   + ++ +DRF+    V K  LQL+G T MF+
Sbjct: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254

Query: 110 ASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMP 169
           ASK +E  P         TDN+    ++ QME+ ++  L + L    P  F+    SK+ 
Sbjct: 255 ASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRR-ASKIG 313

Query: 170 EAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLN 216
           E +  +  + K+    + L   D   +  PPS +AAG+   A++ L+
Sbjct: 314 EVDVEQHTLAKY---LMELTMLDYDMVHFPPSQIAAGAFCLALKILD 357


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 48/178 (26%), Positives = 87/178 (48%), Gaps = 4/178 (2%)

Query: 50  KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109
           +++   MR I+  W+++V  + +  +E   + +  +DRFL ++PV + +LQL+G T + +
Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218

Query: 110 ASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMP 169
           ASK +E      E     TDN+    ++ +ME L++ +LK+ L    P  F+    SK  
Sbjct: 219 ASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRR-ASKAG 277

Query: 170 EAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227
           E +  +  + K+    + L   D   +   PS VAA +   + + L     N    YY
Sbjct: 278 EVDVEQHTLAKY---LMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYY 332


>gi|153791755 cyclin domain containing [Homo sapiens]
          Length = 350

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 50/176 (28%), Positives = 79/176 (44%), Gaps = 4/176 (2%)

Query: 49  QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108
           Q +V    R  + +W++ V  +     E   L +N LDRFL+  PV     QLLG T + 
Sbjct: 125 QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLL 184

Query: 109 VASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKM 168
           +A K  E  P   ++L      +   ++L  +E ++++KL + L A T   F+EHF    
Sbjct: 185 IACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHAR 244

Query: 169 PEAEENKQIIRKHAQTF----VALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSP 220
            EA + +      AQ        L   D  F S  PS++A   +  A + L +  P
Sbjct: 245 VEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP 300


>gi|209915556 cyclin D3 isoform 4 [Homo sapiens]
          Length = 96

 Score = 68.6 bits (166), Expect = 6e-12
 Identities = 42/98 (42%), Positives = 53/98 (54%), Gaps = 5/98 (5%)

Query: 199 PPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESS 258
           PPSM+A GS+ AAVQGL   S    +S   LT  L+ +   + DCLRACQEQIEA L  S
Sbjct: 3   PPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRES 58

Query: 259 LRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
           LR+A Q +  P          +      TPTDV  + +
Sbjct: 59  LREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 96


>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 307

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 37/107 (34%), Positives = 61/107 (57%)

Query: 46  KCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGAT 105
           + + + V P MR +V  W+++V E      +   LA++ LD +LS   V+  RLQLLG  
Sbjct: 97  RALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVA 156

Query: 106 CMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNL 152
           C+FVA KM+E +      LC+ + +S    ELL+ E  ++++L + L
Sbjct: 157 CLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203


>gi|40805832 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 19/201 (9%)

Query: 28  LRAMLKAEETCAPSVSYFKCVQK------EVLPSMRKIVATWMLEVCEEQKCEEEVFPLA 81
           L A+L+ E  C P V   + ++        +   +R      +L + +    + E F LA
Sbjct: 17  LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76

Query: 82  MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKLCIYTDNSIRPEELL 138
           +N LDRFLS   V+   L  +G +C ++A K  E    +PL  + + I +       +L+
Sbjct: 77  VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135

Query: 139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVAL------CATD 192
           +ME +++ K+ W + A T   F++ + S +   +EN  + R+++  F  L      C   
Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLL---QENLPLERRNSINFERLEAQLKACHCR 192

Query: 193 VKFISNPPSMVAAGSVVAAVQ 213
           + F    PS++A   +   +Q
Sbjct: 193 IIFSKAKPSVLALSIIALEIQ 213


>gi|4757934 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 19/201 (9%)

Query: 28  LRAMLKAEETCAPSVSYFKCVQK------EVLPSMRKIVATWMLEVCEEQKCEEEVFPLA 81
           L A+L+ E  C P V   + ++        +   +R      +L + +    + E F LA
Sbjct: 17  LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76

Query: 82  MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKLCIYTDNSIRPEELL 138
           +N LDRFLS   V+   L  +G +C ++A K  E    +PL  + + I +       +L+
Sbjct: 77  VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135

Query: 139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVAL------CATD 192
           +ME +++ K+ W + A T   F++ + S +   +EN  + R+++  F  L      C   
Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLL---QENLPLERRNSINFERLEAQLKACHCR 192

Query: 193 VKFISNPPSMVAAGSVVAAVQ 213
           + F    PS++A   +   +Q
Sbjct: 193 IIFSKAKPSVLALSIIALEIQ 213


>gi|197276674 cyclin J isoform 1 [Homo sapiens]
          Length = 383

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 59/205 (28%), Positives = 100/205 (48%), Gaps = 29/205 (14%)

Query: 80  LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132
           LA+  LD F+    +   +L L+  +C+ +ASK +E   ++P   E+L    C+   N +
Sbjct: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121

Query: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK------------MPEAEENKQIIR 179
             ++ LL MELLL+   +WNL   T   FIE++LS+            M   E+ K  + 
Sbjct: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMA 181

Query: 180 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 239
           K+A  F+ +   D  F++  PS+VAA  V ++   L L SP      +RLT +       
Sbjct: 182 KYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRL-SPTWPTRLHRLTAY------- 233

Query: 240 DPDCLRACQEQIEALLESSLRQAQQ 264
             D L  C E++    ++ +++A +
Sbjct: 234 SWDFLVQCIERLLIAHDNDVKEANK 258


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 45/179 (25%), Positives = 80/179 (44%), Gaps = 4/179 (2%)

Query: 49   QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108
            Q E+   MR I+  W++EV    +   E   LA+  +D +L     KK +LQLLGAT   
Sbjct: 1153 QIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFM 1212

Query: 109  VASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKM 168
            +A+K +E      +      D++ +  E+L ME+ ++N LK ++     +    HFL + 
Sbjct: 1213 IAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAY----HFLRRY 1268

Query: 169  PEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227
                         ++    +   +  ++    S +AA S++ A+    L     FL +Y
Sbjct: 1269 ARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHY 1327


>gi|118572588 cyclin F [Homo sapiens]
          Length = 786

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 6/165 (3%)

Query: 48  VQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCM 107
           VQK +  +MR I+  W++EV   +        L +  +DR+L    V + RLQLLG  CM
Sbjct: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360

Query: 108 FVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSK 167
            + ++      LT  +    TDN+ + E+L++M   +V+ L+  +   T  D+ E  L+ 
Sbjct: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420

Query: 168 MPEAEENKQIIRKHAQTFVA-LCATDVKFISNPPSMVAAGSVVAA 211
           +P      ++  +H  +F+  L        +  P+ +AA +++ A
Sbjct: 421 VP-----VELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLA 460


>gi|5802992 cyclin I [Homo sapiens]
          Length = 377

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 12/122 (9%)

Query: 50  KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109
           + V PS R  V  W+ ++  +     E F LA + LDRFL+        L  +  +C F+
Sbjct: 38  QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97

Query: 110 ASKM---KETIP----LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIE 162
           A+K     E IP    L  +  C          E+L+ME ++++KL W+L   TP DF+ 
Sbjct: 98  AAKTVEEDERIPVLKVLARDSFC-----GCSSSEILRMERIILDKLNWDLHTATPLDFLH 152

Query: 163 HF 164
            F
Sbjct: 153 IF 154


>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
          Length = 291

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 4/152 (2%)

Query: 76  EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE 135
           E   LA+  +D +L     KK +LQLLGAT   +A+K +E      +      D++ +  
Sbjct: 76  ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135

Query: 136 ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKF 195
           E+L ME+ ++N LK ++     +    HFL +              ++    +   +  +
Sbjct: 136 EVLSMEINILNVLKCDINIPIAY----HFLRRYARCIHTNMKTLTLSRYICEMTLQEYHY 191

Query: 196 ISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227
           +    S +AA S++ A+    L     FL +Y
Sbjct: 192 VQEKASKLAAASLLLALYMKKLGYWVPFLEHY 223


>gi|40254889 cyclin J isoform 2 [Homo sapiens]
          Length = 372

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 40/205 (19%)

Query: 80  LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132
           LA+  LD F+    +   +L L+  +C+ +ASK +E   ++P   E+L    C+   N +
Sbjct: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121

Query: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK------------MPEAEENKQIIR 179
             ++ LL MELLL+   +WNL   T   FIE++LS+            M   E+ K  + 
Sbjct: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMA 181

Query: 180 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 239
           K+A  F+ +            S+  A + VA+ + +   SP      +RLT +       
Sbjct: 182 KYADYFLEV------------SLQVAAACVASSRIILRLSPTWPTRLHRLTAY------- 222

Query: 240 DPDCLRACQEQIEALLESSLRQAQQ 264
             D L  C E++    ++ +++A +
Sbjct: 223 SWDFLVQCIERLLIAHDNDVKEANK 247


>gi|4502623 cyclin H [Homo sapiens]
          Length = 323

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 63/274 (22%), Positives = 115/274 (41%), Gaps = 32/274 (11%)

Query: 11  ETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEE 70
           E + R   DAN    R  R    A     P+   F    +E+  ++ K     +LE C  
Sbjct: 17  EQLARLRADAN----RKFRCKAVANGKVLPNDPVFLEPHEEM--TLCKYYEKRLLEFCSV 70

Query: 71  QK--CEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYT 128
            K      V   A  Y  RF     V +   +++  TC F+A K+ E    + + +    
Sbjct: 71  FKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLR 130

Query: 129 DNSIRPE----ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAE---ENKQIIRKH 181
           ++ +  E    ++L+ ELLL+ +L ++L    P+   E FL  +       EN +I+RK 
Sbjct: 131 ESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKT 190

Query: 182 AQTFVALCATDVKFISNPPSMVAAGSVVAAVQ--GLNLRSPNNFLSYYRLTRFLSRVIKC 239
           A  F+   A    ++   PS +A  +++++    G+ + S            +LS  +  
Sbjct: 191 ADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMES------------YLSESLML 238

Query: 240 DPDCLRACQEQIEALLESSLRQAQQNMDPKAAEE 273
             +  R C  Q+  +++ S+R   +  +P  +EE
Sbjct: 239 KEN--RTCLSQLLDIMK-SMRNLVKKYEPPRSEE 269


>gi|197276676 cyclin J isoform 3 [Homo sapiens]
          Length = 371

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 9/96 (9%)

Query: 80  LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132
           LA+  LD F+    +   +L L+  +C+ +ASK +E   ++P   E+L    C+   N +
Sbjct: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121

Query: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK 167
             ++ LL MELLL+   +WNL   T   FIE++LS+
Sbjct: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 5/119 (4%)

Query: 49  QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108
           Q E+  +  ++V  W+L +       +  F LA+    R L    VK+  L     T + 
Sbjct: 143 QDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLR 201

Query: 109 VASKMKET---IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHF 164
           +A+K+ E    IP   +    Y  +   P ELL+MEL ++++L W+L   TP DF+  F
Sbjct: 202 LAAKVNEEEEFIPQVKDFTKHY-GSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIF 259


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 21/145 (14%)

Query: 131 SIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEEN-------------KQI 177
           ++  +ELL  ELLL+    WNL   TP  F++++L      +++             K+ 
Sbjct: 169 TLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKEC 228

Query: 178 IRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVI 237
           ++++A  F+ +   D  F    PS+VAA  V A+   L L SP     Y+  TR L R+ 
Sbjct: 229 LKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQL-SP-----YW--TRDLQRIS 280

Query: 238 KCDPDCLRACQEQIEALLESSLRQA 262
               + L  C E +  + ++ L+ A
Sbjct: 281 SYSLEHLSTCIEILLVVYDNVLKDA 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,171,253
Number of Sequences: 37866
Number of extensions: 469474
Number of successful extensions: 5633
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5262
Number of HSP's gapped (non-prelim): 252
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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