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Search of human proteins with 169218173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
(977 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 2023 0.0
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 2023 0.0
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 1241 0.0
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 1241 0.0
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H... 1149 0.0
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho... 1120 0.0
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H... 1104 0.0
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 1023 0.0
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H... 960 0.0
gi|98986459 jumonji domain containing 2A [Homo sapiens] 137 4e-32
gi|39653317 jumonji domain containing 2D [Homo sapiens] 137 5e-32
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ... 134 4e-31
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 133 7e-31
gi|239755681 PREDICTED: hypothetical protein [Homo sapiens] 133 7e-31
gi|239750150 PREDICTED: hypothetical protein [Homo sapiens] 133 7e-31
gi|239744460 PREDICTED: hypothetical protein [Homo sapiens] 133 7e-31
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 133 7e-31
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 133 7e-31
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 133 7e-31
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 132 1e-30
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 132 1e-30
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 132 1e-30
gi|45504380 jumonji domain containing 2B [Homo sapiens] 132 2e-30
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 1e-13
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 73 1e-12
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 73 1e-12
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 68 5e-11
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 67 1e-10
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 66 2e-10
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 65 2e-10
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 2023 bits (5242), Expect = 0.0
Identities = 977/977 (100%), Positives = 977/977 (100%)
Query: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG
Sbjct: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
Query: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI
Sbjct: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
Query: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN
Sbjct: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
Query: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN
Sbjct: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
Query: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS
Sbjct: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
Query: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE
Sbjct: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED
Sbjct: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC
Sbjct: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
Query: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE
Sbjct: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
Query: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV
Sbjct: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
Query: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE
Sbjct: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
Query: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK
Sbjct: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
Query: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK
Sbjct: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
Query: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN
Sbjct: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
Query: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF
Sbjct: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
Query: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR
Sbjct: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
Query: 961 LQELLTVSEHWDDKAKS 977
LQELLTVSEHWDDKAKS
Sbjct: 961 LQELLTVSEHWDDKAKS 977
Score = 32.7 bits (73), Expect = 1.7
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 307 VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
VD+ +CL C ++ C+ C D++HT C+ P W CP C E
Sbjct: 1174 VDIKICL-CQKAPAAP-MIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSE 1225
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 2023 bits (5242), Expect = 0.0
Identities = 977/977 (100%), Positives = 977/977 (100%)
Query: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG
Sbjct: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
Query: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI
Sbjct: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
Query: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN
Sbjct: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
Query: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN
Sbjct: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
Query: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS
Sbjct: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
Query: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE
Sbjct: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED
Sbjct: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC
Sbjct: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
Query: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE
Sbjct: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
Query: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV
Sbjct: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
Query: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE
Sbjct: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
Query: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK
Sbjct: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
Query: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK
Sbjct: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
Query: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN
Sbjct: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
Query: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF
Sbjct: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
Query: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR
Sbjct: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
Query: 961 LQELLTVSEHWDDKAKS 977
LQELLTVSEHWDDKAKS
Sbjct: 961 LQELLTVSEHWDDKAKS 977
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 1241 bits (3210), Expect = 0.0
Identities = 595/967 (61%), Positives = 741/967 (76%), Gaps = 14/967 (1%)
Query: 17 LGGPGPLG---EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPP 73
+ G GP G EF+PPPECPVFEPSWEEF DP +FI +IRP+AE+TGICK+RPP DWQPP
Sbjct: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
Query: 74 FACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQL 133
FAC+V FTPR+QRLNELEA TRV+L+FLDQ+AK+WELQGSTLKIP VERKILDL+ L
Sbjct: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
Query: 134 NKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRC 193
+K+VA +GGF +V K++KW+K+ +++G+ PGK GS ++ HYERIL PY LF SG SL
Sbjct: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
Query: 194 LQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART 253
+Q PNL D K+K P+ S + P R + +K + E +R
Sbjct: 181 VQMPNL--DLKEKVE-----PEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRN 233
Query: 254 HNLRR-RMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKAT---NAVDL 309
L++ ++ PK + E R+ ++ + R +K T N VDL
Sbjct: 234 TELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDL 293
Query: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFG 369
YVC+ CG GN+ED+LLLCDGCDDSYHTFCLIPPL DVPKGDWRCPKC+A+ECSKP+EAFG
Sbjct: 294 YVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFG 353
Query: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
FEQA R+YTL++FGEMAD FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV VEYGADI
Sbjct: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
Query: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
+SK+FGSGFPV+DG+ K+ PEEEEY SGWNLNNMPV+EQSVLAHI DI GMK+PWLYV
Sbjct: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
Query: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVP +AAEQLE VM++LAPELF SQPDLL
Sbjct: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
Query: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
HQLVTIMNPN LM H VPVYRTNQCAGEFV+TFPRAYHSGFNQG+NFAEAVNFCT DWLP
Sbjct: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
Query: 610 LGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETV 669
+GRQCV HYR L R+CVFSH+E+I KMA+ + LDV +A+ V K++ +M E+E LRE+V
Sbjct: 594 IGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESV 653
Query: 670 RKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYK 729
++GV+ SE FEL+PDDERQC C+TTCF+SA++CSC P LVCL+H +LC CP K
Sbjct: 654 VQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQK 713
Query: 730 YKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMK 789
LRYRY L+DL ++ +K+RA+SY+ W V EAL A N KK L+ + ++E++E +
Sbjct: 714 KCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDR 773
Query: 790 KFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQL 849
K+P+NDL R LR ++AE CASVAQ LL+ K++ R G+++ +LTV EL+ FV QL
Sbjct: 774 KYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQL 833
Query: 850 YALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAE 909
++LPCV+SQ +K+LL+ VE+F + +Q+ + +ETP +++LQ L+D+ VELP+L
Sbjct: 834 FSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPR 893
Query: 910 MRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSE 969
++ L+QARWL+EV+ DP +TLD M++LID GVGLAP+ AVEKAMA LQELLTVSE
Sbjct: 894 LKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
Query: 970 HWDDKAK 976
W++KAK
Sbjct: 954 RWEEKAK 960
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 1241 bits (3210), Expect = 0.0
Identities = 595/967 (61%), Positives = 741/967 (76%), Gaps = 14/967 (1%)
Query: 17 LGGPGPLG---EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPP 73
+ G GP G EF+PPPECPVFEPSWEEF DP +FI +IRP+AE+TGICK+RPP DWQPP
Sbjct: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
Query: 74 FACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQL 133
FAC+V FTPR+QRLNELEA TRV+L+FLDQ+AK+WELQGSTLKIP VERKILDL+ L
Sbjct: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
Query: 134 NKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRC 193
+K+VA +GGF +V K++KW+K+ +++G+ PGK GS ++ HYERIL PY LF SG SL
Sbjct: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
Query: 194 LQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART 253
+Q PNL D K+K P+ S + P R + +K + E +R
Sbjct: 181 VQMPNL--DLKEKVE-----PEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRN 233
Query: 254 HNLRR-RMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKAT---NAVDL 309
L++ ++ PK + E R+ ++ + R +K T N VDL
Sbjct: 234 TELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDL 293
Query: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFG 369
YVC+ CG GN+ED+LLLCDGCDDSYHTFCLIPPL DVPKGDWRCPKC+A+ECSKP+EAFG
Sbjct: 294 YVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFG 353
Query: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
FEQA R+YTL++FGEMAD FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV VEYGADI
Sbjct: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
Query: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
+SK+FGSGFPV+DG+ K+ PEEEEY SGWNLNNMPV+EQSVLAHI DI GMK+PWLYV
Sbjct: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
Query: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVP +AAEQLE VM++LAPELF SQPDLL
Sbjct: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
Query: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
HQLVTIMNPN LM H VPVYRTNQCAGEFV+TFPRAYHSGFNQG+NFAEAVNFCT DWLP
Sbjct: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
Query: 610 LGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETV 669
+GRQCV HYR L R+CVFSH+E+I KMA+ + LDV +A+ V K++ +M E+E LRE+V
Sbjct: 594 IGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESV 653
Query: 670 RKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYK 729
++GV+ SE FEL+PDDERQC C+TTCF+SA++CSC P LVCL+H +LC CP K
Sbjct: 654 VQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQK 713
Query: 730 YKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMK 789
LRYRY L+DL ++ +K+RA+SY+ W V EAL A N KK L+ + ++E++E +
Sbjct: 714 KCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDR 773
Query: 790 KFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQL 849
K+P+NDL R LR ++AE CASVAQ LL+ K++ R G+++ +LTV EL+ FV QL
Sbjct: 774 KYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQL 833
Query: 850 YALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAE 909
++LPCV+SQ +K+LL+ VE+F + +Q+ + +ETP +++LQ L+D+ VELP+L
Sbjct: 834 FSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPR 893
Query: 910 MRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSE 969
++ L+QARWL+EV+ DP +TLD M++LID GVGLAP+ AVEKAMA LQELLTVSE
Sbjct: 894 LKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
Query: 970 HWDDKAK 976
W++KAK
Sbjct: 954 RWEEKAK 960
>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
sapiens]
Length = 1560
Score = 1149 bits (2972), Expect = 0.0
Identities = 564/988 (57%), Positives = 725/988 (73%), Gaps = 44/988 (4%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
+FLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 DFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PRIQRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VER+ILDL+ L+K+V EEGG+
Sbjct: 67 PRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYE 126
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSL-RCLQKPNLTTDT 203
+CKDR+W ++A ++ + PGK +GS +R HYERI+ PY ++ SG +L +C +P +
Sbjct: 127 AICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP-FDNEE 185
Query: 204 KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTE------------- 250
KDKEYKPH IP RQSVQPS+ RRAKR++ + + + E+ E
Sbjct: 186 KDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKM 245
Query: 251 ------ARTHNLRRR----MGCPTPKCENEKEMKSSIKQEPIERKDYIVENEK--EKPKS 298
A+ LR++ CP P ++E+ +K E K ++ E+ P+
Sbjct: 246 MGLGLMAKDKTLRKKDKEGPECP-PTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEP 304
Query: 299 RSKKA-------TNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKG 349
+K +NA ++ YVC +C G+++D+LLLCDGCDD+YH FCL+PPL ++PKG
Sbjct: 305 CTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKG 364
Query: 350 DWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKE 409
WRCPKC+ EC +P EAFGFEQA R+YTL++FGEMAD+FK+DYFNMPVHMVPTELVEKE
Sbjct: 365 VWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKE 424
Query: 410 FWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQ 469
FWRLV++IEEDVTVEYGADI SKEFGSGFPV D K L+PEEEEY SGWNLN MPV+EQ
Sbjct: 425 FWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQ 484
Query: 470 SVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQ 529
SVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVP AAE
Sbjct: 485 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 544
Query: 530 LENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSG 589
LE VMKKL PELF SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVITFPRAYHSG
Sbjct: 545 LEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 604
Query: 590 FNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVAS 649
FNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+ + LD+ +A+
Sbjct: 605 FNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAA 664
Query: 650 TVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCK 709
V K+M IM+++E+ LR+ + + G+ ++ER FELLPDDERQC+KCKTTCF+SA++C
Sbjct: 665 AVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDC 724
Query: 710 PGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAK 769
P LVCL H+ +LC C + LRYRYTLD+L M++ LK+RAES++ WA V ALE +
Sbjct: 725 PDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVE 784
Query: 770 INKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSG 829
+K+SL +AL E+ ++FP+++LL+ L+ +AE C S A L++G+ +R
Sbjct: 785 DGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVA 844
Query: 830 GGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAE 889
G Q+T+ ELR F+ Q+ LPC + Q +K +L +VE +Q +++ L+ S
Sbjct: 845 G----LQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 900
Query: 890 LQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDMRRLIDLGVG 947
LQ LL+ + VE+P+ +++ ++EQARWL+EV++ L PS+ TL MR L+ G
Sbjct: 901 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRT-LAPSARRGTLAVMRGLLVAGAS 959
Query: 948 LAPYSAVEKAMARLQELLTVSEHWDDKA 975
+AP AV+KA A LQELLT++E W++KA
Sbjct: 960 VAPSPAVDKAQAELQELLTIAERWEEKA 987
>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
sapiens]
Length = 1539
Score = 1120 bits (2896), Expect = 0.0
Identities = 542/977 (55%), Positives = 710/977 (72%), Gaps = 35/977 (3%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
EFLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERKILDL+ L+K+V EEGG+
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSG-DSLRCLQKPNLTTDT 203
+CKDR+W ++A ++ + PGK +GS +R HYERI+ PY +F SG + ++C P +
Sbjct: 127 AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP-FDNEV 185
Query: 204 KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART---------- 253
KDKEYKPH IP RQSVQPS+ +RRAKR++ + + + E+ E +
Sbjct: 186 KDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKM 245
Query: 254 -----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKK 302
+ +++ CP +++ + ++ +E + K
Sbjct: 246 MGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKN 305
Query: 303 ATNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
++A +D Y+C +C G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+ E
Sbjct: 306 HSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAE 365
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
C +P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEED
Sbjct: 366 CKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED 425
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
VTVEYGADI SKEFGSGFPV + K LSPEE+EY SGWNLN MPV++QSVL HI ADI
Sbjct: 426 VTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADIS 485
Query: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
GMK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVP AAE LE VMK L PE
Sbjct: 486 GMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPE 545
Query: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
LF SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVITFPRAYHSGFNQG+NFAEAV
Sbjct: 546 LFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAV 605
Query: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
NFCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+ + LD+ +A V K+M IM++
Sbjct: 606 NFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQ 665
Query: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
+E+ LR+ + + GV ++ER FELLPDDERQC+KCKTTCF+SA++C P LVCL H+
Sbjct: 666 EERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHIN 725
Query: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
+LC C + LRYRYTLD+L M++ LK+RAES++ WA V ALE + +K+S +
Sbjct: 726 DLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELR 785
Query: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
AL E+ ++FP+++LL+ L+ + E C + L++G+ QLT+
Sbjct: 786 ALESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQ-------VARMDTPQLTLT 838
Query: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
ELR + Q+ +LPC + Q +KD+L +VE +Q +++ L+ S L+ LL+ +
Sbjct: 839 ELRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQL 898
Query: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDMRRLIDLGVGLAPYSAVEKAM 958
VE+P+ +++ ++EQA+WL+EV+QA L PS+ +L M+ L+ +G +A +V+KA
Sbjct: 899 GVEVPEAHQLQQQVEQAQWLDEVKQA-LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKAR 957
Query: 959 ARLQELLTVSEHWDDKA 975
A LQELLT++E W++KA
Sbjct: 958 AELQELLTIAERWEEKA 974
>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
sapiens]
Length = 1570
Score = 1104 bits (2855), Expect = 0.0
Identities = 542/1008 (53%), Positives = 710/1008 (70%), Gaps = 66/1008 (6%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
EFLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERKILDL+ L+K+V EEGG+
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSG-DSLRCLQKPNLTTDT 203
+CKDR+W ++A ++ + PGK +GS +R HYERI+ PY +F SG + ++C P +
Sbjct: 127 AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP-FDNEV 185
Query: 204 KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART---------- 253
KDKEYKPH IP RQSVQPS+ +RRAKR++ + + + E+ E +
Sbjct: 186 KDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKM 245
Query: 254 -----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKK 302
+ +++ CP +++ + ++ +E + K
Sbjct: 246 MGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKN 305
Query: 303 ATNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
++A +D Y+C +C G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+ E
Sbjct: 306 HSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAE 365
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
C +P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEED
Sbjct: 366 CKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED 425
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEE----------------------------- 451
VTVEYGADI SKEFGSGFPV + K LSPEE
Sbjct: 426 VTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPPKVL 485
Query: 452 --EEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSIN 509
+EY SGWNLN MPV++QSVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSIN
Sbjct: 486 GLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSIN 545
Query: 510 YLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVY 569
YLHWGEPKTWYGVP AAE LE VMK L PELF SQPDLLHQLVT+MNPNTLM+H VPV
Sbjct: 546 YLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVV 605
Query: 570 RTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSH 629
RTNQCAGEFVITFPRAYHSGFNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH
Sbjct: 606 RTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSH 665
Query: 630 DEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDE 689
+E+ICKMA+ + LD+ +A V K+M IM+++E+ LR+ + + GV ++ER FELLPDDE
Sbjct: 666 EELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDDE 725
Query: 690 RQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALK 749
RQC+KCKTTCF+SA++C P LVCL H+ +LC C + LRYRYTLD+L M++ LK
Sbjct: 726 RQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLK 785
Query: 750 LRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEK 809
+RAES++ WA V ALE + +K+S +AL E+ ++FP+++LL+ L+ + E
Sbjct: 786 IRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSEVEA 845
Query: 810 CASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRV 869
C + L++G+ QLT+ ELR + Q+ +LPC + Q +KD+L +V
Sbjct: 846 CIAQVLGLVSGQ-------VARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQV 898
Query: 870 EDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLD 929
E +Q +++ L+ S L+ LL+ + VE+P+ +++ ++EQA+WL+EV+QA L
Sbjct: 899 EAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA-LA 957
Query: 930 PSSL--TLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKA 975
PS+ +L M+ L+ +G +A +V+KA A LQELLT++E W++KA
Sbjct: 958 PSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKA 1005
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 1023 bits (2644), Expect = 0.0
Identities = 514/976 (52%), Positives = 667/976 (68%), Gaps = 90/976 (9%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
EFLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERK
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERK------------------ 108
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTK 204
IL+ Y+L S +C P + K
Sbjct: 109 ---------------------------------ILDLYSL-----SKQCNTHP-FDNEVK 129
Query: 205 DKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART----------- 253
DKEYKPH IP RQSVQPS+ +RRAKR++ + + + E+ E +
Sbjct: 130 DKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKMM 189
Query: 254 ----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKA 303
+ +++ CP +++ + ++ +E + K
Sbjct: 190 GLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKNH 249
Query: 304 TNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQEC 361
++A +D Y+C +C G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+ EC
Sbjct: 250 SSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAEC 309
Query: 362 SKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDV 421
+P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV
Sbjct: 310 KQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDV 369
Query: 422 TVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICG 481
TVEYGADI SKEFGSGFPV + K LSPEE+EY SGWNLN MPV++QSVL HI ADI G
Sbjct: 370 TVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADISG 429
Query: 482 MKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPEL 541
MK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVP AAE LE VMK L PEL
Sbjct: 430 MKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPEL 489
Query: 542 FVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVN 601
F SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVITFPRAYHSGFNQG+NFAEAVN
Sbjct: 490 FDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVN 549
Query: 602 FCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIED 661
FCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+ + LD+ +A V K+M IM+++
Sbjct: 550 FCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQE 609
Query: 662 EKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKE 721
E+ LR+ + + GV ++ER FELLPDDERQC+KCKTTCF+SA++C P LVCL H+ +
Sbjct: 610 ERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHIND 669
Query: 722 LCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKA 781
LC C + LRYRYTLD+L M++ LK+RAES++ WA V ALE + +K+S +A
Sbjct: 670 LCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRA 729
Query: 782 LIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNE 841
L E+ ++FP+++LL+ L+ + E C + L++G+ QLT+ E
Sbjct: 730 LESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQ-------VARMDTPQLTLTE 782
Query: 842 LRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFD 901
LR + Q+ +LPC + Q +KD+L +VE +Q +++ L+ S L+ LL+ +
Sbjct: 783 LRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQLG 842
Query: 902 VELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDMRRLIDLGVGLAPYSAVEKAMA 959
VE+P+ +++ ++EQA+WL+EV+QA L PS+ +L M+ L+ +G +A +V+KA A
Sbjct: 843 VEVPEAHQLQQQVEQAQWLDEVKQA-LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARA 901
Query: 960 RLQELLTVSEHWDDKA 975
LQELLT++E W++KA
Sbjct: 902 ELQELLTIAERWEEKA 917
>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
sapiens]
Length = 1379
Score = 960 bits (2481), Expect = 0.0
Identities = 478/877 (54%), Positives = 625/877 (71%), Gaps = 44/877 (5%)
Query: 136 LVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSL-RCL 194
+V EEGG+ +CKDR+W ++A ++ + PGK +GS +R HYERI+ PY ++ SG +L +C
Sbjct: 51 IVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCN 110
Query: 195 QKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTE---- 250
+P + KDKEYKPH IP RQSVQPS+ RRAKR++ + + + E+ E
Sbjct: 111 TRP-FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKL 169
Query: 251 ---------------ARTHNLRRR----MGCPTPKCENEKEMKSSIKQEPIERKDYIVEN 291
A+ LR++ CP P ++E+ +K E K ++
Sbjct: 170 QIYGAGPKMMGLGLMAKDKTLRKKDKEGPECP-PTVVVKEELGGDVKVESTSPKTFLESK 228
Query: 292 EK--EKPKSRSKKA-------TNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLI 340
E+ P+ +K +NA ++ YVC +C G+++D+LLLCDGCDD+YH FCL+
Sbjct: 229 EELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLL 288
Query: 341 PPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHM 400
PPL ++PKG WRCPKC+ EC +P EAFGFEQA R+YTL++FGEMAD+FK+DYFNMPVHM
Sbjct: 289 PPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHM 348
Query: 401 VPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWN 460
VPTELVEKEFWRLV++IEEDVTVEYGADI SKEFGSGFPV D K L+PEEEEY SGWN
Sbjct: 349 VPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWN 408
Query: 461 LNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWY 520
LN MPV+EQSVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWY
Sbjct: 409 LNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWY 468
Query: 521 GVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVI 580
GVP AAE LE VMKKL PELF SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVI
Sbjct: 469 GVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVI 528
Query: 581 TFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKA 640
TFPRAYHSGFNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+
Sbjct: 529 TFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACP 588
Query: 641 DVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCF 700
+ LD+ +A+ V K+M IM+++E+ LR+ + + G+ ++ER FELLPDDERQC+KCKTTCF
Sbjct: 589 EKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCF 648
Query: 701 MSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWAL 760
+SA++C P LVCL H+ +LC C + LRYRYTLD+L M++ LK+RAES++ WA
Sbjct: 649 LSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWAN 708
Query: 761 NVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNG 820
V ALE + +K+SL +AL E+ ++FP+++LL+ L+ +AE C S A L++G
Sbjct: 709 KVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSG 768
Query: 821 KRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLL 880
+ +R G Q+T+ ELR F+ Q+ LPC + Q +K +L +VE +Q +++ L
Sbjct: 769 QEAGPHRVAG----LQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREAL 824
Query: 881 SEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDM 938
+ S LQ LL+ + VE+P+ +++ ++EQARWL+EV++ L PS+ TL M
Sbjct: 825 ASLPSSPGLLQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRT-LAPSARRGTLAVM 883
Query: 939 RRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKA 975
R L+ G +AP AV+KA A LQELLT++E W++KA
Sbjct: 884 RGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKA 920
Score = 81.6 bits (200), Expect = 3e-15
Identities = 33/43 (76%), Positives = 38/43 (88%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPP 67
+FLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP
Sbjct: 7 DFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPP 49
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 137 bits (346), Expect = 4e-32
Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 26/238 (10%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T+R F ++A+ SD + P + EL E+++W+ + T + YGAD+ +
Sbjct: 93 TVREFRKIAN---SDKYCTPRYSEFEEL-ERKYWKNL-TFNPPI---YGADVNGTLY--- 141
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
E+++D WN+ + + V I G+ P+LY GM +SF
Sbjct: 142 --------------EKHVDE-WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFA 186
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY VP ++LE + K P S L +T+++
Sbjct: 187 WHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLIS 246
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCV 615
P L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF T W+ G+Q V
Sbjct: 247 PLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 28 PPPECPVFEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC-DVDKLHFTP 85
P F P+ EEF + +I I A + G+ KV PP +W+P + D+D L
Sbjct: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
Query: 86 RIQRL 90
IQ+L
Sbjct: 70 PIQQL 74
>gi|39653317 jumonji domain containing 2D [Homo sapiens]
Length = 523
Score = 137 bits (345), Expect = 5e-32
Identities = 83/243 (34%), Positives = 117/243 (48%), Gaps = 23/243 (9%)
Query: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
F Q + T GE S + P H +L E+++W+ + I YGADI
Sbjct: 86 FTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDL-ERKYWK--NRIYNSPI--YGADI 140
Query: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
+ F WNL ++ ++ + I G+ P+LY
Sbjct: 141 SGSLFDEN------------------TKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYF 182
Query: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
GM ++F WH ED YSINYLH GEPKTWY VP ++LE + ++L P L
Sbjct: 183 GMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFL 242
Query: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
V +++P L + +P R Q AGEF++TFP YH+GFN GFN AEA+NF T W+
Sbjct: 243 RHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWID 302
Query: 610 LGR 612
G+
Sbjct: 303 YGK 305
>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
sapiens]
Length = 1246
Score = 134 bits (337), Expect = 4e-31
Identities = 111/396 (28%), Positives = 183/396 (46%), Gaps = 39/396 (9%)
Query: 375 RDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEF 434
R +L TF A S F+ P E +E+E+WRLV + V V G + +
Sbjct: 818 RSVSLTTFYRTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTH 873
Query: 435 GSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFS 494
GSGFPV GK E + GWNL +P S+L H+ A + G+ +PWL +GM FS
Sbjct: 874 GSGFPV--GK------SEPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFS 924
Query: 495 SFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVT 554
+ CW + + I+YLH G WY +P +LE+V+ L +L V
Sbjct: 925 TSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVM 984
Query: 555 IMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQC 614
I +P L + V+RT Q +G+FV+ FP ++ S G++ +E V+F T W +G +
Sbjct: 985 I-SPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFET 1043
Query: 615 VEHYRLLHRYCVFSHDEMICKMA-SKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLG 673
+ + H FS ++++ ++A ++A + ST+ + + + E R + + G
Sbjct: 1044 AKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAG 1103
Query: 674 VIDSER-----------------MDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVC- 715
+ S R + L ER+C C+ C++S + ++ C
Sbjct: 1104 LHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMV-VQENENVVFCL 1162
Query: 716 ---LHHVKELCSCPPYKYKLRYRYTLDDLYPMMNAL 748
L HV++ SC KL YRY + + ++N +
Sbjct: 1163 ECALRHVEKQKSC--RGLKLMYRYDEEQIISLVNQI 1196
Score = 79.0 bits (193), Expect = 2e-14
Identities = 45/127 (35%), Positives = 71/127 (55%), Gaps = 2/127 (1%)
Query: 31 ECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRL 90
E PV PS +EF DP +I +R E+ G+C+V PPPDW+P + D++ F +IQ +
Sbjct: 556 EIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLN-DEMRFVTQIQHI 614
Query: 91 NELEAQTRVKLNFLDQIAKYWELQGSTL-KIPHVERKILDLFQLNKLVAEEGGFAVVCKD 149
++L + + L I K+ + QG T+ ++P + LDL +L+ E GG V
Sbjct: 615 HKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDL 674
Query: 150 RKWTKIA 156
+KW K+A
Sbjct: 675 KKWNKLA 681
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 133 bits (335), Expect = 7e-31
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
Query: 85 PRIQRL 90
IQ++
Sbjct: 71 APIQQM 76
>gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 133 bits (335), Expect = 7e-31
Identities = 64/154 (41%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP + LE + ++L P++ L V +++P L + +P Q AGEF
Sbjct: 209 WYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
Score = 30.4 bits (67), Expect = 8.5
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 35 FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQ 71
F P+ EEFAD ++ + A Q G+ KV PP +W+
Sbjct: 18 FYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWK 55
>gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 133 bits (335), Expect = 7e-31
Identities = 64/154 (41%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP + LE + ++L P++ L V +++P L + +P Q AGEF
Sbjct: 209 WYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
Score = 30.4 bits (67), Expect = 8.5
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 35 FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQ 71
F P+ EEFAD ++ + A Q G+ KV PP +W+
Sbjct: 18 FYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWK 55
>gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 133 bits (335), Expect = 7e-31
Identities = 64/154 (41%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP + LE + ++L P++ L V +++P L + +P Q AGEF
Sbjct: 209 WYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
Score = 30.4 bits (67), Expect = 8.5
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 35 FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQ 71
F P+ EEFAD ++ + A Q G+ KV PP +W+
Sbjct: 18 FYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWK 55
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 133 bits (335), Expect = 7e-31
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 117 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 168
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 169 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 210
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 211 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 270
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 271 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 325
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 34 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 92
Query: 85 PRIQRL 90
IQ++
Sbjct: 93 APIQQM 98
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 133 bits (335), Expect = 7e-31
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
Query: 85 PRIQRL 90
IQ++
Sbjct: 71 APIQQM 76
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 133 bits (335), Expect = 7e-31
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
Query: 85 PRIQRL 90
IQ++
Sbjct: 71 APIQQM 76
>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 132 bits (333), Expect = 1e-30
Identities = 65/154 (42%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP ++LE + ++L P L V +++P L + +P R Q AGEF
Sbjct: 209 WYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 132 bits (333), Expect = 1e-30
Identities = 65/154 (42%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP ++LE + ++L P L V +++P L + +P R Q AGEF
Sbjct: 209 WYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 132 bits (333), Expect = 1e-30
Identities = 65/154 (42%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP ++LE + ++L P L V +++P L + +P R Q AGEF
Sbjct: 209 WYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 132 bits (331), Expect = 2e-30
Identities = 77/232 (33%), Positives = 116/232 (50%), Gaps = 23/232 (9%)
Query: 381 TFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPV 440
T GE S+ + P H +L E+++W+ ++ V+ YGADI+ +
Sbjct: 94 TVGEYRRLANSEKYCTPRHQDFDDL-ERKYWKNLTF----VSPIYGADISGSLYDDDV-- 146
Query: 441 RDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHI 500
+ WN+ ++ + V I G+ P+LY GM ++F WH
Sbjct: 147 ----------------AQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHT 190
Query: 501 EDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNT 560
ED YSINYLH+GEPK+WY +P ++LE + P L +T+++P
Sbjct: 191 EDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPII 250
Query: 561 LMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
L + +P R Q AGEF+ITFP YH+GFN GFN AE+ NF T+ W+ G+
Sbjct: 251 LKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGK 302
Score = 32.7 bits (73), Expect = 1.7
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQP 72
P C + F P+ EEF D ++ I A + G+ K+ PP +W+P
Sbjct: 11 PSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKP 56
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 76.3 bits (186), Expect = 1e-13
Identities = 34/71 (47%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 302 KATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLA-QE 360
K V+ VC +CG +D RLLLCD CD SYHT+CL PPL VPKG W+C C++ +
Sbjct: 1420 KGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQ 1479
Query: 361 CSKPQEAFGFE 371
C F E
Sbjct: 1480 CGAASPGFHCE 1490
Score = 58.5 bits (140), Expect = 3e-08
Identities = 20/59 (33%), Positives = 33/59 (55%)
Query: 298 SRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKC 356
+R + + VC C ++ ++L+C+ CD YHTFCL PP+ ++P W+C C
Sbjct: 262 ARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKAC 320
Score = 40.4 bits (93), Expect = 0.008
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Query: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKC-LAQECSKP 364
C +C + L C C YH CL L + W+CP+C + Q C KP
Sbjct: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKP 282
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 72.8 bits (177), Expect = 1e-12
Identities = 30/56 (53%), Positives = 35/56 (62%)
Query: 302 KATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCL 357
K ++ VC CG D RLLLCD CD SYHT+CL PPL VPKG W+C C+
Sbjct: 1000 KGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
Score = 57.4 bits (137), Expect = 6e-08
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 311 VCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKC-LAQEC 361
VC C ++ ++L+CD CD YHTFCL P + VP W+C C + EC
Sbjct: 390 VCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIEC 441
Score = 40.0 bits (92), Expect = 0.011
Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 294 EKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRC 353
++ RSK+ N C +C S D C C YH CL + + + W+C
Sbjct: 332 DQAPERSKEDAN------CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQC 385
Query: 354 PKC-LAQECSKPQE 366
P+C + Q C + E
Sbjct: 386 PECKVCQNCKQSGE 399
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 72.8 bits (177), Expect = 1e-12
Identities = 31/63 (49%), Positives = 38/63 (60%)
Query: 296 PKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK 355
P +K + D C +CG + EDRLLLCDGCD YH CL PPL +VP +W CP+
Sbjct: 170 PVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPE 229
Query: 356 CLA 358
C A
Sbjct: 230 CAA 232
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 67.8 bits (164), Expect = 5e-11
Identities = 33/74 (44%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 283 ERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPP 342
E+ E E+EK S++A A D C CG N + +LLCD CD YHT CL PP
Sbjct: 868 EKSSAASEEEEEK---ESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPP 924
Query: 343 LHDVPKGDWRCPKC 356
L +P G+W CP C
Sbjct: 925 LMIIPDGEWFCPPC 938
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 66.6 bits (161), Expect = 1e-10
Identities = 44/157 (28%), Positives = 76/157 (48%), Gaps = 32/157 (20%)
Query: 261 GCPTPKCENEK-EMKSSIKQEPIERKDYIVENEK-----EKPKSRSKKATNAVDLYV--- 311
G PK + K + + S K E ++ + +VE K EK K+ ++A ++V
Sbjct: 1111 GFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLG 1170
Query: 312 ----------------CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK 355
C +C ++D+L+LCD C+ ++H FCL P L++VP G+W+CP
Sbjct: 1171 MLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPA 1230
Query: 356 CLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSD 392
C Q + + + G R+YT + E ++ +SD
Sbjct: 1231 C--QPATARRNSRG-----RNYTEESASEDSEDDESD 1260
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 65.9 bits (159), Expect = 2e-10
Identities = 28/62 (45%), Positives = 39/62 (62%)
Query: 299 RSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLA 358
RS +V+ CL+C G++++ LLLCDGCD H +C P + VP+GDW C CLA
Sbjct: 1666 RSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLA 1725
Query: 359 QE 360
Q+
Sbjct: 1726 QQ 1727
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 65.5 bits (158), Expect = 2e-10
Identities = 24/48 (50%), Positives = 33/48 (68%)
Query: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQ 359
C +C G++E+ LLLCDGCD HT+C P + +P GDW CP C+A+
Sbjct: 1934 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAK 1981
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,205,747
Number of Sequences: 37866
Number of extensions: 2049899
Number of successful extensions: 7357
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 6960
Number of HSP's gapped (non-prelim): 445
length of query: 977
length of database: 18,247,518
effective HSP length: 112
effective length of query: 865
effective length of database: 14,006,526
effective search space: 12115644990
effective search space used: 12115644990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.