Guide to the Human Genome
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Search of human proteins with 169214604

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169214604 PREDICTED: hypothetical protein [Homo sapiens]
         (583 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169214604 PREDICTED: hypothetical protein [Homo sapiens]          1164   0.0  
gi|169214874 PREDICTED: hypothetical protein [Homo sapiens]          1151   0.0  
gi|169215109 PREDICTED: hypothetical protein [Homo sapiens]          1151   0.0  
gi|239757495 PREDICTED: hypothetical protein [Homo sapiens]            55   2e-07
gi|239752012 PREDICTED: hypothetical protein XP_002348067 [Homo ...    55   2e-07
gi|239746497 PREDICTED: hypothetical protein XP_002343747 [Homo ...    55   2e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    43   0.001
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              41   0.003
gi|239754209 PREDICTED: hypothetical protein [Homo sapiens]            39   0.017
gi|239748740 PREDICTED: hypothetical protein [Homo sapiens]            39   0.017
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         37   0.065
gi|207452735 epiplakin 1 [Homo sapiens]                                36   0.086
gi|60097902 filaggrin [Homo sapiens]                                   36   0.11 
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ...    35   0.19 
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ...    35   0.19 
gi|60218906 golgi autoantigen, golgin subfamily a, 8F [Homo sapi...    35   0.19 
gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo sap...    35   0.19 
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            35   0.19 
gi|60218910 golgi autoantigen, golgin subfamily a, 8G [Homo sapi...    35   0.19 
gi|62122917 filaggrin family member 2 [Homo sapiens]                   35   0.25 
gi|110611218 ribosome binding protein 1 [Homo sapiens]                 35   0.25 
gi|110611220 ribosome binding protein 1 [Homo sapiens]                 35   0.25 
gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Hom...    35   0.25 
gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]    34   0.32 
gi|91208420 bassoon protein [Homo sapiens]                             34   0.42 
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    34   0.42 
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    33   0.55 
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho...    33   0.55 
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...    33   0.55 
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            33   0.72 

>gi|169214604 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 583

 Score = 1164 bits (3010), Expect = 0.0
 Identities = 583/583 (100%), Positives = 583/583 (100%)

Query: 1   MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL 60
           MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL
Sbjct: 1   MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL 60

Query: 61  ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120
           ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD
Sbjct: 61  ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120

Query: 121 AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ 180
           AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ
Sbjct: 121 AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ 180

Query: 181 DAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG 240
           DAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG
Sbjct: 181 DAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG 240

Query: 241 RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCW 300
           RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCW
Sbjct: 241 RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCW 300

Query: 301 ASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH 360
           ASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH
Sbjct: 301 ASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH 360

Query: 361 LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA 420
           LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA
Sbjct: 361 LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA 420

Query: 421 ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV 480
           ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV
Sbjct: 421 ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV 480

Query: 481 VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR 540
           VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR
Sbjct: 481 VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR 540

Query: 541 PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR 583
           PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR
Sbjct: 541 PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR 583


>gi|169214874 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 583

 Score = 1151 bits (2977), Expect = 0.0
 Identities = 579/583 (99%), Positives = 579/583 (99%)

Query: 1   MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL 60
           MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL
Sbjct: 1   MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL 60

Query: 61  ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120
           ELQVGAGEGVEDGGDWEGHEQDAAQ AAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD
Sbjct: 61  ELQVGAGEGVEDGGDWEGHEQDAAQYAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120

Query: 121 AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ 180
           AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ
Sbjct: 121 AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ 180

Query: 181 DAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG 240
           DAQRPQHAQHQPHLVQVAVARAGLATA GGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG
Sbjct: 181 DAQRPQHAQHQPHLVQVAVARAGLATARGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG 240

Query: 241 RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCW 300
           RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKG QKLCPVPCW
Sbjct: 241 RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGAQKLCPVPCW 300

Query: 301 ASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH 360
           ASQAEGPQAATW PYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH
Sbjct: 301 ASQAEGPQAATWEPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH 360

Query: 361 LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA 420
           LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA
Sbjct: 361 LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA 420

Query: 421 ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV 480
           ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV
Sbjct: 421 ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV 480

Query: 481 VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR 540
           VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR
Sbjct: 481 VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR 540

Query: 541 PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR 583
           PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR
Sbjct: 541 PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR 583


>gi|169215109 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 583

 Score = 1151 bits (2977), Expect = 0.0
 Identities = 579/583 (99%), Positives = 579/583 (99%)

Query: 1   MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL 60
           MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL
Sbjct: 1   MASGHRWQAGQACPPRSVIVSGVRGGTSEQDVTVLGHAQLRLGFDEELRPPEHHPLLLLL 60

Query: 61  ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120
           ELQVGAGEGVEDGGDWEGHEQDAAQ AAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD
Sbjct: 61  ELQVGAGEGVEDGGDWEGHEQDAAQYAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120

Query: 121 AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ 180
           AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ
Sbjct: 121 AGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ 180

Query: 181 DAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG 240
           DAQRPQHAQHQPHLVQVAVARAGLATA GGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG
Sbjct: 181 DAQRPQHAQHQPHLVQVAVARAGLATARGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAG 240

Query: 241 RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCW 300
           RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKG QKLCPVPCW
Sbjct: 241 RLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGAQKLCPVPCW 300

Query: 301 ASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH 360
           ASQAEGPQAATW PYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH
Sbjct: 301 ASQAEGPQAATWEPYFHAYKDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEH 360

Query: 361 LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA 420
           LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA
Sbjct: 361 LARQPRVRPLHHVAQSPHAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQVA 420

Query: 421 ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV 480
           ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV
Sbjct: 421 ALAAAVQVVLRDAPVQQLLLEGQRAHLAQQPQLARAQEGQDSAEGPRVAVEEELVAGDVV 480

Query: 481 VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR 540
           VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR
Sbjct: 481 VIAHVEDVVEVGAGLELAQARQRELVQRGPGQRVLDAAYVDDDPTAAVLGLTALAGLILR 540

Query: 541 PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR 583
           PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR
Sbjct: 541 PQPLRPAVERALDGLALREEGRVEGGVRGAAQRAVVVVRIVSR 583


>gi|239757495 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 111

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 172 VARQAHHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQR 231
           +ARQ  + +DA     A+H  HL QVA   A L   C  +  QQR++ GQ  H VD+ +R
Sbjct: 1   MARQLEYAEDAHE---AEHLHHLAQVAELLAALVAQCHTS--QQREIEGQHRHNVDEVER 55

Query: 232 APQEGELAGRLNEPQEELQGEPAHAHRL 259
             +E    GR  E +  L+ EP  A  L
Sbjct: 56  VAEEVARTGRQQEARRHLEAEPGDAEVL 83


>gi|239752012 PREDICTED: hypothetical protein XP_002348067 [Homo
           sapiens]
          Length = 111

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 172 VARQAHHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQR 231
           +ARQ  + +DA     A+H  HL QVA   A L   C  +  QQR++ GQ  H VD+ +R
Sbjct: 1   MARQLEYAEDAHE---AEHLHHLAQVAELLAALVAQCHTS--QQREIEGQHRHNVDEVER 55

Query: 232 APQEGELAGRLNEPQEELQGEPAHAHRL 259
             +E    GR  E +  L+ EP  A  L
Sbjct: 56  VAEEVARTGRQQEARRHLEAEPGDAEVL 83


>gi|239746497 PREDICTED: hypothetical protein XP_002343747 [Homo
           sapiens]
          Length = 111

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 172 VARQAHHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQR 231
           +ARQ  + +DA     A+H  HL QVA   A L   C  +  QQR++ GQ  H VD+ +R
Sbjct: 1   MARQLEYAEDAHE---AEHLHHLAQVAELLAALVAQCHTS--QQREIEGQHRHNVDEVER 55

Query: 232 APQEGELAGRLNEPQEELQGEPAHAHRL 259
             +E    GR  E +  L+ EP  A  L
Sbjct: 56  VAEEVARTGRQQEARRHLEAEPGDAEVL 83


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/186 (21%), Positives = 73/186 (39%), Gaps = 15/186 (8%)

Query: 65   GAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHG---DDSPPVAGRDA 121
            G GEG E+ G+WEG E++  +   +      G  G+         G   ++     G + 
Sbjct: 944  GEGEGEEEEGEWEGEEEE-GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002

Query: 122  GELGAVGHLVLDDVEQGR-------EEGDGHAEEEQQE---PELAGAAAGREPQRLQPQG 171
            GE    G    ++ E+G        EEG+G  EEE+ E    E      G E +R + + 
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062

Query: 172  VARQAHHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQR 231
               +  + +  +     Q      +V+  + G         +Q++ V    G+  +QR +
Sbjct: 1063 EEEEGKYQETGEEENERQDGEEYKKVSKIK-GSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121

Query: 232  APQEGE 237
             P + +
Sbjct: 1122 MPVQSK 1127



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 49/230 (21%), Positives = 82/230 (35%), Gaps = 19/230 (8%)

Query: 67   GEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGA 126
            GEG E+ G+ E  E +  ++  +G     G  G+         G+      G   GE   
Sbjct: 833  GEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE-EGEGEGEEEG 891

Query: 127  VGHLVLDDVE-QGREEGDGHAEEEQQE--PELAGAAAGREPQRLQPQGVARQAHHVQDAQ 183
             G    ++ E +G EEG+G  EEE+ E   E  G     E +  + +G         + +
Sbjct: 892  EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951

Query: 184  RPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAGRLN 243
              +                G      G   ++ +  G++G    + +    EGE      
Sbjct: 952  EGEW--------------EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997

Query: 244  EPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQK 293
            E +EE +GE        +E+     G V  GE G   G       +G ++
Sbjct: 998  EGEEEGEGEEEGEGEGEEEEEGEVEGEVE-GEEGEGEGEEEEGEEEGEER 1046



 Score = 36.6 bits (83), Expect = 0.065
 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%)

Query: 61   ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120
            E + G GEG E+ G+ EG + +   +  +G +      G+           +     G  
Sbjct: 924  EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE--GEGEEEGEGEGEEGEGEG 981

Query: 121  AGELGAVGHLVLDDVEQGREEGDGHAE-----EEQQEPELAGAAAGRE 163
              E G       +  E+G EEG+G  E     EE++E E+ G   G E
Sbjct: 982  EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 48/231 (20%), Positives = 84/231 (36%), Gaps = 26/231 (11%)

Query: 65   GAGEGVEDGGDWEGHE-QDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVA-GRDAG 122
            G GE  E+GG+ EG E ++   +  +      G   +         G++      G + G
Sbjct: 803  GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862

Query: 123  ELGAVGHLVLDDVEQGRE-EGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQD 181
            E G       +  E+G E EG+G  EE + E E  G   G E +  + +G        ++
Sbjct: 863  EEG-------EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG-EGEGEEEGEGEGEE 914

Query: 182  AQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAGR 241
             +     + +    +            G    ++ +  G+DG    + +    EGE    
Sbjct: 915  EEGEGKGEEEGEEGE------------GEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962

Query: 242  LNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQ 292
              E +EE +GE        +E+     G     E G + G   G   + G+
Sbjct: 963  EGEGEEEGEGEGEEGEGEGEEEEGEGEGE---EEEGEEEGEEEGEGEEEGE 1010



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 43/206 (20%), Positives = 79/206 (38%), Gaps = 14/206 (6%)

Query: 61   ELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD 120
            E + G GEG E+ G+ EG E+       +G        G+          ++     G +
Sbjct: 870  EGEEGEGEGEEEEGEGEGEEE------GEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923

Query: 121  AGELGAVGHLVLDDVEQGREEGDGHAEEEQQE---PELAGAAAGREPQRLQPQGVARQAH 177
             GE G  G    ++ E   E+G+G  EEE+ E    E  G   G E    + +G   +  
Sbjct: 924  EGEEGE-GEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEG--EGEGEEGEGE 980

Query: 178  HVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGE 237
              ++    +  + +                  G   ++ +V G+   +  + +   +EGE
Sbjct: 981  GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 238  LAGRLNEPQEELQGEPAHAHRLHDED 263
              G   E ++E +GE    +R  +E+
Sbjct: 1041 EEG--EEREKEGEGEENRRNREEEEE 1064



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 51/240 (21%), Positives = 86/240 (35%), Gaps = 35/240 (14%)

Query: 24  RGGTSEQDVTVLGHAQLRLGFDEELRPPEH-HPLLLLLELQVGA----GEGVEDGGDWEG 78
           R G  E+++      + R G ++E +  E  H      E++ G     GEG E+ GD E 
Sbjct: 688 RPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747

Query: 79  HEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQG 138
            E+   +   +G        G+ V     R  ++        AG+            E+G
Sbjct: 748 EEEKEGEGKEEGE-------GEEVE--GEREKEEGERKKEERAGK-----------EEKG 787

Query: 139 REEGD-GHAEEEQ-----QEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRPQHAQHQP 192
            EEGD G  EEE+     +E E  G   G E +    +G   +    ++ +  +      
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE----EGKGEREEEEEEGEGEEEEGEGE 843

Query: 193 HLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAGRLNEPQEELQGE 252
                     G           + +  G++G    + +    EGE  G     +EE +GE
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 77/349 (22%), Positives = 123/349 (35%), Gaps = 54/349 (15%)

Query: 67   GEGV----EDGGDWEGHEQDAAQDAAQGHYLARG-APGDHVAIAHRRHGDDSP------- 114
            GEG+    E GG   GHE +   +AA G     G + G     A    G+  P       
Sbjct: 1794 GEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEA 1853

Query: 115  PVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQE---------PELAGAAAGREPQ 165
            P A  DA E         +DVE    EG+   E E  E         PE  GA A    +
Sbjct: 1854 PEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEK 1913

Query: 166  RLQPQGVARQAHHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQ 225
              QP+  + +A   +    P+    +    + A   A       G    + +V+  +  +
Sbjct: 1914 EAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEA------EGQTQPESEVI--ESQE 1965

Query: 226  VDQRQRAPQEGELAGRLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDA----G 281
             ++  +   E   A  +    +E +GE     +   EDV A      + E   +A     
Sbjct: 1966 AEEEAQPESEDVEALEVEVETQEAEGEA----QPESEDVEAPEAEGEMQEAEEEAQPESD 2021

Query: 282  GVSGPSRKGGQKLCPVPCWASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQGA 341
            GV    +  G++   V     + EG              D      G+ +       Q A
Sbjct: 2022 GVEAQPKSEGEEAQEVEGETQKTEG--------------DAQPESDGVEAPEAEEEAQEA 2067

Query: 342  DGEVDGGDGHEEHRQAGEHLARQP--RVRPLHHVAQSPHAAPQAALALG 388
            +GEV   +G E H ++ +  A++     +P     ++P A  +A  A G
Sbjct: 2068 EGEVQEAEG-EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 53/238 (22%), Positives = 86/238 (36%), Gaps = 22/238 (9%)

Query: 71   EDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELG----- 125
            ED  + EG E   A++AAQ    A G       +   +  ++       D   L      
Sbjct: 1930 EDEPESEGAEAQEAEEAAQE---AEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVET 1986

Query: 126  --AVGHLV--LDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQ- 180
              A G      +DVE    EG+    EE+ +PE  G  A  + +  + Q V  +    + 
Sbjct: 1987 QEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEG 2046

Query: 181  DAQRPQHAQHQPHLVQVAVARAGLATACGGAVH-QQRDVVGQDGHQVDQRQ----RAPQ- 234
            DAQ        P   + A    G      G  H +  DV  Q+     Q +     AP+ 
Sbjct: 2047 DAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEA 2106

Query: 235  --EGELAGRLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKG 290
              E + A  +  P+ E + +P  +  +   +        + G   +DA G + P  +G
Sbjct: 2107 EGEAQKAEGIEAPETEGEAQP-ESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 41/191 (21%), Positives = 66/191 (34%), Gaps = 7/191 (3%)

Query: 64   VGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGE 123
            V A E   D  + EG  Q  ++D           P            +  P   G +A E
Sbjct: 1851 VEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPE 1910

Query: 124  LGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQ 183
                     + VE    EG+   E E  E + A  AA     + QP+    ++   ++  
Sbjct: 1911 AEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEA 1970

Query: 184  RPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAGRLN 243
            +P+    +   V+V    A      G A  +  DV   +     + Q A +E +      
Sbjct: 1971 QPESEDVEALEVEVETQEAE-----GEAQPESEDVEAPEAE--GEMQEAEEEAQPESDGV 2023

Query: 244  EPQEELQGEPA 254
            E Q + +GE A
Sbjct: 2024 EAQPKSEGEEA 2034



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 10/128 (7%)

Query: 68   EGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAV 127
            EG+E   + EG  Q  ++            P      A    G+  P   G +A E    
Sbjct: 2114 EGIE-APETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEE 2172

Query: 128  GHLVLDDVEQGREEGDGHAEEE---------QQEPELAGAAAGREPQRLQPQGVARQAHH 178
                L+ VE    EG+   E E         + +PEL G  A    +  QP+    +   
Sbjct: 2173 AQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPE 2232

Query: 179  VQDAQRPQ 186
             +   +P+
Sbjct: 2233 AEGEAQPE 2240



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 31/136 (22%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 52   EHHPLLLLLELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGD 111
            E HP    ++ Q   GE   +    E  E +     A+G      AP           G 
Sbjct: 2077 EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIE----APETEGEAQPESEGI 2132

Query: 112  DSPPVAGRDAGELGAVGHLVLDDVEQGREEG-DGHAEEEQQEPELAGAAAGREPQRLQPQ 170
            ++P   G    E   V     +   Q   EG +    EE+ +PEL G  A       QP+
Sbjct: 2133 EAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPE 2192

Query: 171  GVARQAHHVQDAQRPQ 186
                +A   +   +P+
Sbjct: 2193 SEGIEAPEAEGEAQPE 2208


>gi|239754209 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 278

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 59/198 (29%), Positives = 71/198 (35%), Gaps = 32/198 (16%)

Query: 35  LGHAQLRLGFDEELRPPEHHPLLLLLELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLA 94
           L HA  R+   E L P     LL     Q+  G  V D G    H Q A +D A G    
Sbjct: 50  LVHALARVPVQEGLAPEHGRELLGDALEQLLDGRAVADEGG--RHLQAAGRDVAHGRLHV 107

Query: 95  RGAPGDHVA----------IAHRRHGDDSPPVAG-RDAGELGAV--GHLVLDDVEQGREE 141
            G P   VA          + H  HG  +P     R    +  V  GH VL       E 
Sbjct: 108 VGDPLHEVAAVLVLHVEHLLVHLLHGHAAPEDGSHRQVAAVARVAGGHHVLGVEHLLGEL 167

Query: 142 GDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRPQHAQHQPHLVQVAVAR 201
           G       ++ P L  A AG+  +    +  AR+ HHV       H Q    L QV V  
Sbjct: 168 G------HRERPVLLAAPAGQGREAGHEEVQAREGHHV-------HRQ----LAQVCVQL 210

Query: 202 AGLATACGGAVHQQRDVV 219
           A  A A G   H  R  V
Sbjct: 211 AREAQAGGDPAHGGRHQV 228


>gi|239748740 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 278

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 59/198 (29%), Positives = 71/198 (35%), Gaps = 32/198 (16%)

Query: 35  LGHAQLRLGFDEELRPPEHHPLLLLLELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLA 94
           L HA  R+   E L P     LL     Q+  G  V D G    H Q A +D A G    
Sbjct: 50  LVHALARVPVQEGLAPEHGRELLGDALEQLLDGRAVADEGG--RHLQAAGRDVAHGRLHV 107

Query: 95  RGAPGDHVA----------IAHRRHGDDSPPVAG-RDAGELGAV--GHLVLDDVEQGREE 141
            G P   VA          + H  HG  +P     R    +  V  GH VL       E 
Sbjct: 108 VGDPLHEVAAVLVLHVEHLLVHLLHGHAAPEDGSHRQVAAVARVAGGHHVLGVEHLLGEL 167

Query: 142 GDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRPQHAQHQPHLVQVAVAR 201
           G       ++ P L  A AG+  +    +  AR+ HHV       H Q    L QV V  
Sbjct: 168 G------HRERPVLLAAPAGQGREAGHEEVQAREGHHV-------HRQ----LAQVCVQL 210

Query: 202 AGLATACGGAVHQQRDVV 219
           A  A A G   H  R  V
Sbjct: 211 AREAQAGGDPAHGGRHQV 228


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 36.6 bits (83), Expect = 0.065
 Identities = 43/138 (31%), Positives = 57/138 (41%), Gaps = 23/138 (16%)

Query: 144 GHAEEEQQEPELAGAAAG------REPQRLQPQGVARQAHHVQDAQRPQHAQHQPHLVQV 197
           G +  + + P   G AAG      R+P+R  P+           AQ     +H P  + V
Sbjct: 629 GASRAQARLPHSGGPAAGGGRQLKRDPER--PESAKAFGREGSGAQGEAEVRHPPVGIAV 686

Query: 198 AVARAGLATACG----GAVHQQR-----DVVGQ---DGHQVDQRQRAPQEGELAGRLNEP 245
           AVAR   +   G    G V Q+R     +V G    D   VD R R  +E  L  RL+  
Sbjct: 687 AVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHGRADEDCVDDRARHREERLLGARLDRD 746

Query: 246 QEEL---QGEPAHAHRLH 260
           QE+L     E A   RLH
Sbjct: 747 QEKLLRESKELADLARLH 764


>gi|207452735 epiplakin 1 [Homo sapiens]
          Length = 5090

 Score = 36.2 bits (82), Expect = 0.086
 Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 13/75 (17%)

Query: 94   ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
            A  APG    +   R G   P  AGR  G+              GR + +G  E E QE 
Sbjct: 2578 AEEAPGARPQLQDARRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 2624

Query: 154  ELAGAAAGREPQRLQ 168
              A AAA R+ Q L+
Sbjct: 2625 AAAAAAARRQEQTLR 2639



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)

Query: 94   ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
            A  APG    +     G   P  AGR  G+              GR + +G  E E QE 
Sbjct: 3112 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 3158

Query: 154  ELAGAAAGREPQRLQ 168
              A AAA R+ Q L+
Sbjct: 3159 AAAAAAARRQEQTLR 3173



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)

Query: 94   ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
            A  APG    +     G   P  AGR  G+              GR + +G  E E QE 
Sbjct: 3646 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 3692

Query: 154  ELAGAAAGREPQRLQ 168
              A AAA R+ Q L+
Sbjct: 3693 AAAAAAARRQEQTLR 3707



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)

Query: 94   ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
            A  APG    +     G   P  AGR  G+              GR + +G  E E QE 
Sbjct: 4714 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 4760

Query: 154  ELAGAAAGREPQRLQ 168
              A AAA R+ Q L+
Sbjct: 4761 AAAAAAARRQEQTLR 4775



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)

Query: 94   ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
            A  APG    +     G   P  AGR  G+              GR + +G  E E QE 
Sbjct: 4180 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 4226

Query: 154  ELAGAAAGREPQRLQ 168
              A AAA R+ Q L+
Sbjct: 4227 AAATAAARRQEQTLR 4241


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 70/342 (20%), Positives = 110/342 (32%), Gaps = 56/342 (16%)

Query: 80   EQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDS---------PPVAGRDAGELGAVGHL 130
            E  +   AA  H  AR +PG+     H++  D S            A RD+G  G+ G  
Sbjct: 1011 ETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQ 1070

Query: 131  VLDDVEQGREEGD-----GHAEE-------EQQEPELAGAAAGREPQRLQPQGVARQA-- 176
              D  E   EE D     GH ++       ++   + +G  +GR    +       Q+  
Sbjct: 1071 ASDS-EGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSES 1129

Query: 177  ---------------HHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQ 221
                           HH Q     +H+  Q     +            G+ H+Q   V +
Sbjct: 1130 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQS--VDR 1187

Query: 222  DGHQVDQRQRAPQEGELAGRLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAG 281
             GH          +G             Q     A R   +D  +  G+   G R  +A 
Sbjct: 1188 SGHSGSHHSHTTSQGR------SDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAA 1241

Query: 282  GVSGPSRKG--GQKLCPVPCWASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKYLAGQ 339
              +  SR    GQ+        S+    Q ++ +    + +   D +   GS  +   G 
Sbjct: 1242 SWADSSRHSQVGQEQSS----GSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGS 1297

Query: 340  GADGEVDGGDG---HEEHRQAGEHLARQPRVRPLHHVAQSPH 378
              +   DG      H+E R +  H A   R    HH   S H
Sbjct: 1298 SREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSH 1339



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 45/222 (20%), Positives = 79/222 (35%), Gaps = 38/222 (17%)

Query: 66   AGEGVEDGGDW----------EGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPP 115
            A   V D G W          EGH +++   +  GH    G  G H     + H + +  
Sbjct: 1054 ASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGH----GQDGPH----QQSHQESARD 1105

Query: 116  VAGRDAGELGAVGHLVLDDVEQ-----------GREEGDGHAEEEQQEPELAGAAAGREP 164
             +G  +G  G+  + V    +            GR +G  H E+ +     + +  G++ 
Sbjct: 1106 WSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQG-SHHEQARDSSRHSASQEGQDT 1164

Query: 165  QRLQP---QGVARQAHHVQDAQRPQHA-QHQPHLVQVAVARA--GLATACGGAVHQQRDV 218
             R  P   +G  + +HH Q   R  H+  H  H      + A  G + +   +   ++D 
Sbjct: 1165 IRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDK 1224

Query: 219  VGQDG--HQVDQRQRAPQEGELAGRLNEPQEELQGEPAHAHR 258
               DG  H   +   A    + +      QE+  G     H+
Sbjct: 1225 QSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQ 1266



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 61/257 (23%), Positives = 86/257 (33%), Gaps = 52/257 (20%)

Query: 67   GEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD-AGELG 125
            G  V    D EGH +D+ + +       RG+     A    RHG   P     D AG   
Sbjct: 943  GSSVSQDSDSEGHSEDSERWSGSASRNHRGS-----AQEQSRHGSRHPRSHHEDRAGH-- 995

Query: 126  AVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRP 185
              GH      +  R+ G  HAE         G AA    Q     G    + H Q A   
Sbjct: 996  --GH----SADSSRQSGTPHAETSS-----GGQAASSHEQARSSPGERHGSRHQQSADSS 1044

Query: 186  QHAQHQPHLVQVAVARAGLATACGGAV-----HQQRDVV------GQDG-HQVDQRQRAP 233
            +H+         AV  +G   + G        H +          GQDG HQ   ++ A 
Sbjct: 1045 RHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESAR 1104

Query: 234  Q-EGELAGR----LNEPQEELQGEPAH------------AHRLHDEDVVAHLGTVALGER 276
               G  +GR    + +     Q E AH            +H     D   H    +  + 
Sbjct: 1105 DWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH----SASQE 1160

Query: 277  GRDAGGVSGPSRKGGQK 293
            G+D       SR+GG++
Sbjct: 1161 GQDTIRAHPGSRRGGRQ 1177



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 61/257 (23%), Positives = 86/257 (33%), Gaps = 53/257 (20%)

Query: 67   GEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRD-AGELG 125
            G  V    D EGH +D+ + +       RG+  +       RHG   P     D AG   
Sbjct: 3212 GSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE-----QSRHGSRHPRSHHEDRAGH-- 3264

Query: 126  AVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRP 185
              GH      ++ R+ G  HAE         G AA    Q     G    + H Q A   
Sbjct: 3265 --GH----SADRSRQSGTRHAETSS-----GGQAASSHEQARSSPGERHGSRHQQSADSS 3313

Query: 186  QHAQHQPHLVQVAV------ARAGLATACGGAVHQQRDVVGQDGH-QVDQRQRAPQE--- 235
            +H+         AV        +G   +      ++ D     GH Q    Q++ QE   
Sbjct: 3314 RHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESAR 3373

Query: 236  ---GELAGR----LNEPQEELQGEPAH------------AHRLHDEDVVAHLGTVALGER 276
               G  +GR    L +     Q E AH            +H     D   H    +  + 
Sbjct: 3374 DRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH----SASQE 3429

Query: 277  GRDA-GGVSGPSRKGGQ 292
            G+D   G  G SR+G Q
Sbjct: 3430 GQDTIRGHPGSSRRGRQ 3446



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 32/137 (23%), Positives = 47/137 (34%), Gaps = 14/137 (10%)

Query: 67  GEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGA 126
           G       D EGH +++   +  GH  A      H      R G+ S    GR    L  
Sbjct: 416 GSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERS----GRSGSSLYQ 471

Query: 127 VGHLVLDDVEQGRE------EGDGHAEEEQQEPELAGAAAGREPQRLQP---QGVARQAH 177
           V      D   GR           H E+ +     + +  G++  R  P   +G  + +H
Sbjct: 472 VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531

Query: 178 HVQDAQRPQHA-QHQPH 193
           H Q   R  H+  H  H
Sbjct: 532 HEQSVNRSGHSGSHHSH 548


>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
           [Homo sapiens]
          Length = 806

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 23/111 (20%)

Query: 68  EGVE--DGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELG 125
           EG+   DG   E  E++ A  AA       G   +  A +   +GDD     G D  ELG
Sbjct: 94  EGISALDGDQMELGEENGAAGAADS-----GPMEEEEAASEDENGDDQGFQEGED--ELG 146

Query: 126 AVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQA 176
                   D E+G  + +GH E++ Q P      A ++ Q  Q +G A++A
Sbjct: 147 --------DEEEGAGDENGHGEQQPQPP------ATQQQQPQQQRGAAKEA 183


>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
           [Homo sapiens]
          Length = 825

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 23/111 (20%)

Query: 68  EGVE--DGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELG 125
           EG+   DG   E  E++ A  AA       G   +  A +   +GDD     G D  ELG
Sbjct: 94  EGISALDGDQMELGEENGAAGAADS-----GPMEEEEAASEDENGDDQGFQEGED--ELG 146

Query: 126 AVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQA 176
                   D E+G  + +GH E++ Q P      A ++ Q  Q +G A++A
Sbjct: 147 --------DEEEGAGDENGHGEQQPQPP------ATQQQQPQQQRGAAKEA 183


>gi|60218906 golgi autoantigen, golgin subfamily a, 8F [Homo
           sapiens]
          Length = 283

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 17/46 (36%), Positives = 23/46 (50%)

Query: 66  AGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGD 111
           AG+GV  GGD++GH +         H  + GAP      A  +HGD
Sbjct: 178 AGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGD 223


>gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo
           sapiens]
          Length = 430

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 17/46 (36%), Positives = 23/46 (50%)

Query: 66  AGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGD 111
           AG+GV  GGD++GH +         H  + GAP      A  +HGD
Sbjct: 325 AGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGD 370


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 79/341 (23%), Positives = 119/341 (34%), Gaps = 66/341 (19%)

Query: 67  GEGVEDGGDWEGHE-QDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELG 125
           GE    GG+ EG E  + A++A +G    + A G          G D  P A    G  G
Sbjct: 29  GEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGG---------GPDRGPEA-EARGTRG 78

Query: 126 AVGHLVLDD-------VEQGREEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVA-RQAH 177
           A G    ++       V QG EE  G  + E       GA+ GR  Q  +P+G A R+  
Sbjct: 79  AHGETEAEEGAPEGAEVPQGGEETSGAQQVE-------GASPGRGAQG-EPRGEAQREPE 130

Query: 178 HVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGE 237
                +R + A+ +P + +          +  G      D  G  G  ++    A    E
Sbjct: 131 DSAAPERQEEAEQRPEVPE---------GSASGEAGDSVDAEGPLGDNIEAEGPAGDSVE 181

Query: 238 LAGRLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPV 297
             GR+ +  +      A        D    LG     E G     V    R G       
Sbjct: 182 AEGRVGDSVD------AEGPAGDSVDAEGPLGDNIQAE-GPAGDSVDAEGRVGD------ 228

Query: 298 PCWASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLKY--LAGQGADGEVDGGDGHEEHR 355
              +  AEGP             D +D +  +G  ++    AG G +  V  GD  E   
Sbjct: 229 ---SVDAEGPAG-----------DSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEG 274

Query: 356 QAGEHLARQPRVRPLHHVAQSPHAAPQAALA-LGRALAVAA 395
            AG+ +  +        V+  P  +   +L+    A+ VAA
Sbjct: 275 PAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAA 315


>gi|60218910 golgi autoantigen, golgin subfamily a, 8G [Homo
           sapiens]
          Length = 434

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 17/46 (36%), Positives = 23/46 (50%)

Query: 66  AGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGD 111
           AG+GV  GGD++GH +         H  + GAP      A  +HGD
Sbjct: 329 AGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGD 374


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 71/319 (22%), Positives = 104/319 (32%), Gaps = 51/319 (15%)

Query: 67   GEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHG------DDSPPVAGRD 120
            G G  +  D EG+   +   +   H  AR   G+  +I H RHG       D+   A   
Sbjct: 1725 GSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSG 1784

Query: 121  AGELGAVGHLVLDDVEQGREE---GDGHAEEEQQEPELAGAAAGRE-PQRLQPQGVARQA 176
             G+    G         G  E    +GH+   Q+ P   G   G+   Q  + + +  + 
Sbjct: 1785 HGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQR-PHSRGHTHGQAGSQHGESESIVDER 1843

Query: 177  H---HVQDAQRPQHAQH------QPHLVQVAVARAGLATACGGAVHQQRDVVGQDGHQVD 227
            H   H Q      H+Q       Q         R+G + +    VH         GH   
Sbjct: 1844 HGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHT-HSGH--T 1900

Query: 228  QRQRAPQEGELAGRLNEPQEELQGEPA----HAHRLHDEDVVAHLGTVALGERGRDAGGV 283
              Q   Q GE    +++  +   G+      H H  H + +    G+   G RG      
Sbjct: 1901 HSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTI--QTGSRTTGRRG------ 1952

Query: 284  SGPSRKGGQKLCPVPCWASQAEGPQAATWTPYFHAYKDRLDLDLGLGSVLK----YLAGQ 339
            SG S              S +EGP   + T   H +          GS +        GQ
Sbjct: 1953 SGHSE------------YSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQ 2000

Query: 340  GADGEVDGGDGHEEHRQAG 358
             AD    G  GH +  Q G
Sbjct: 2001 TADTTRHGHSGHGQSTQRG 2019


>gi|110611218 ribosome binding protein 1 [Homo sapiens]
          Length = 977

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 82/373 (21%), Positives = 135/373 (36%), Gaps = 52/373 (13%)

Query: 140 EEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRPQHAQHQPHLVQVAV 199
           E+ +   ++EQQ   L   AA  E Q LQ Q   R++   ++A + +  +    L     
Sbjct: 407 EKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRES---EEALQKRLDEVSRELCHTQS 463

Query: 200 ARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAGRLNEPQEELQGEPAHAHRL 259
           + A L      A  QQ+                 Q  EL  +L   + E++ +      L
Sbjct: 464 SHASLRADAEKAQEQQQ-----------------QMAELHSKLQSSEAEVRSKCEELSGL 506

Query: 260 HDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCWASQAEGPQAATWTPYFHAY 319
           H +   A      L ER R    +     + GQ        ASQAE  Q  T        
Sbjct: 507 HGQLQEARAENSQLTERIRSIEALL----EAGQARDAQDVQASQAEADQQQT------RL 556

Query: 320 KDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEHLA--RQPRVRPLHHVAQSP 377
           K+      GL      L       +V   D  E++ +A E LA   Q     LH + Q+ 
Sbjct: 557 KELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQAK 616

Query: 378 HAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQV------------AALAAA 425
             + +    +      A LA+   +  L   +  E L  L+             A  ++ 
Sbjct: 617 EESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSD 676

Query: 426 VQVVLRDAPVQQLLLEGQ----RAHLAQQP----QLARAQEGQDSAEGPRVAVEEELVAG 477
           +   LR+A   Q  L+ +    R+ LA+       L ++ E ++     +V   EE +  
Sbjct: 677 LASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQK 736

Query: 478 DVVVIAHVEDVVE 490
             V + H+E++VE
Sbjct: 737 SRVTVKHLEEIVE 749


>gi|110611220 ribosome binding protein 1 [Homo sapiens]
          Length = 977

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 82/373 (21%), Positives = 135/373 (36%), Gaps = 52/373 (13%)

Query: 140 EEGDGHAEEEQQEPELAGAAAGREPQRLQPQGVARQAHHVQDAQRPQHAQHQPHLVQVAV 199
           E+ +   ++EQQ   L   AA  E Q LQ Q   R++   ++A + +  +    L     
Sbjct: 407 EKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRES---EEALQKRLDEVSRELCHTQS 463

Query: 200 ARAGLATACGGAVHQQRDVVGQDGHQVDQRQRAPQEGELAGRLNEPQEELQGEPAHAHRL 259
           + A L      A  QQ+                 Q  EL  +L   + E++ +      L
Sbjct: 464 SHASLRADAEKAQEQQQ-----------------QMAELHSKLQSSEAEVRSKCEELSGL 506

Query: 260 HDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQKLCPVPCWASQAEGPQAATWTPYFHAY 319
           H +   A      L ER R    +     + GQ        ASQAE  Q  T        
Sbjct: 507 HGQLQEARAENSQLTERIRSIEALL----EAGQARDAQDVQASQAEADQQQT------RL 556

Query: 320 KDRLDLDLGLGSVLKYLAGQGADGEVDGGDGHEEHRQAGEHLA--RQPRVRPLHHVAQSP 377
           K+      GL      L       +V   D  E++ +A E LA   Q     LH + Q+ 
Sbjct: 557 KELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQAK 616

Query: 378 HAAPQAALALGRALAVAALAVQRVVLFLPLHHLRELLNLLQV------------AALAAA 425
             + +    +      A LA+   +  L   +  E L  L+             A  ++ 
Sbjct: 617 EESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSD 676

Query: 426 VQVVLRDAPVQQLLLEGQ----RAHLAQQP----QLARAQEGQDSAEGPRVAVEEELVAG 477
           +   LR+A   Q  L+ +    R+ LA+       L ++ E ++     +V   EE +  
Sbjct: 677 LASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQK 736

Query: 478 DVVVIAHVEDVVE 490
             V + H+E++VE
Sbjct: 737 SRVTVKHLEEIVE 749


>gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Homo
           sapiens]
          Length = 802

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 41/146 (28%), Positives = 52/146 (35%), Gaps = 35/146 (23%)

Query: 37  HAQLRLGFDEELRPPEHHPLLLLLELQVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARG 96
           H+ LRLG +   R            L  G+G G    G   G E  + +    G  ++R 
Sbjct: 206 HSSLRLGRNSAARA-----------LISGSGTGAAREGKASGMEARSVE--MSGDRVSRP 252

Query: 97  APGDHVAIAHRRHGD---------DSPPVAGRDAGE-------LGAVGHLVLDDVEQGRE 140
           APGD       R GD         + PP+  R   E       L +V +    DV   RE
Sbjct: 253 APGDS------REGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARE 306

Query: 141 EGDGHAEEEQQEPELAGAAAGREPQR 166
                 EEE    E  GA  G  P R
Sbjct: 307 LRRQQREEEGPGDEAEGAEEGPGPPR 332


>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 11/111 (9%)

Query: 63  QVGAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAG 122
           Q  AG+G +D G  +G  Q   Q   QG    +G P         + G   PP  GR  G
Sbjct: 57  QPSAGDGNQDDGPQQGPPQQGGQQ-QQGPPPPQGKPQ-----GPPQQGGHPPPPQGRPQG 110

Query: 123 ELGAVGHLVLDDVEQGREEGDGHAEEEQQ--EPELAGAAAGREPQRLQPQG 171
                GH       +GR +G       QQ   P   G   G  PQ  +PQG
Sbjct: 111 PPQQGGH---PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQG 158



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 8/123 (6%)

Query: 70  VEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGH 129
           + DGGD E    +  Q    G   ++ + GD        + DD P       G     G 
Sbjct: 32  ISDGGDSEQFLDEERQGPPLGGQQSQPSAGDG-------NQDDGPQQGPPQQGGQQQQGP 84

Query: 130 LVLDDVEQGREEGDGHAEEEQQEPELAGAAAGR-EPQRLQPQGVARQAHHVQDAQRPQHA 188
                  QG  +  GH    Q  P+      G   P R +PQG  +Q  H Q    P   
Sbjct: 85  PPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPG 144

Query: 189 QHQ 191
           + Q
Sbjct: 145 KPQ 147


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 38/141 (26%), Positives = 52/141 (36%), Gaps = 23/141 (16%)

Query: 96   GAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEE---EQQE 152
            G PG H +    RHGD     +GR  GE            E GR     HA +    +  
Sbjct: 3634 GGPGRHASAKEHRHGDHGRH-SGRHTGE------------EPGRRAAKPHARDLGRHEAR 3680

Query: 153  PELAGAAAGREPQRLQPQGVARQAHHVQDAQRPQHAQHQPHLVQVAVARAGLATACGGAV 212
            P    ++A   P++ QP G    A + Q + R   A H       + ++ G   A  G  
Sbjct: 3681 PHSQPSSAPAMPKKGQP-GYPSSAEYSQPS-RASSAYH-----HASDSKKGSRQAHSGPA 3733

Query: 213  HQQRDVVGQDGHQVDQRQRAP 233
              Q     Q   Q+  RQ AP
Sbjct: 3734 ALQSKAEPQAQPQLQGRQAAP 3754


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 21/57 (36%), Positives = 28/57 (49%)

Query: 237  ELAGRLNEPQEELQGEPAHAHRLHDEDVVAHLGTVALGERGRDAGGVSGPSRKGGQK 293
            EL  R  E +EEL+ E A   R+  +   A      L ER  +AGG S   R+G +K
Sbjct: 1159 ELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRK 1215


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 34/146 (23%), Positives = 44/146 (30%), Gaps = 19/146 (13%)

Query: 65  GAGEGVEDGGDWEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRH---------GDDSPP 115
           G G G+  GG    HE           +     PG  +   HR H         G    P
Sbjct: 740 GPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRP 799

Query: 116 VAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPELAGAAAGRE--------PQRL 167
             G   G  G  GH   +    G   G GH   E     + G+   R         P   
Sbjct: 800 HEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGH 859

Query: 168 QPQGVARQAHHVQDAQRPQHAQHQPH 193
           +P  V    H   D + P   +H+ H
Sbjct: 860 RPHDV--PGHRGHDHRGPPPHEHRGH 883


>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
           sapiens]
          Length = 584

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 12/88 (13%)

Query: 228 QRQRAPQ-EGELAGRLNEPQEELQ-----GEPAHAHRLHDEDVVAHLGTVA--LGERGRD 279
           +R+ +P+ EGE AG++   +++ +     G P  A        +A L  VA  LG   +D
Sbjct: 380 RRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKD 439

Query: 280 AGGVSGPSRKGGQKLCPVPCWASQAEGP 307
            GG  GP R GG      P  +S A+ P
Sbjct: 440 PGGGGGPVRAGGAS----PAASSTAQPP 463


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 16/99 (16%)

Query: 61  ELQVGAGEGVEDGGD--------WEGHEQDAAQDAAQGHYLARGAPGDHVAIAHRRHGDD 112
           E QV AG  +E G          WE  ++  A+   +     +   G H A   +  G+D
Sbjct: 760 EAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGED 819

Query: 113 SPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQ 151
           S        G  G        +V + RE GDG AE +Q+
Sbjct: 820 SRSPEAATEGGAG--------EVSKERESGDGEAEGDQR 850


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 13/117 (11%)

Query: 93  LARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGR--------EEGDG 144
           LA G  G+H      R G+    + G+   +     H VL  ++QG         +    
Sbjct: 399 LAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHP 458

Query: 145 HAEEEQQEPELAGAAAGREPQRLQPQGVARQAHH---VQDA--QRPQHAQHQPHLVQ 196
           H +++QQ+ +       ++ Q+ Q Q      HH   +QDA  Q+ QHA  Q  ++Q
Sbjct: 459 HQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQ 515


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,928,291
Number of Sequences: 37866
Number of extensions: 1294453
Number of successful extensions: 5058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 4836
Number of HSP's gapped (non-prelim): 264
length of query: 583
length of database: 18,247,518
effective HSP length: 108
effective length of query: 475
effective length of database: 14,157,990
effective search space: 6725045250
effective search space used: 6725045250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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