Search of human proteins with 112420977

Search of human proteins with 112420977

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
         (1119 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]        2179   0.0  
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]        2032   0.0  
gi|21361794 TIP120 protein [Homo sapiens]                            1231   0.0  
gi|62460637 importin 4 [Homo sapiens]                                  69   3e-11
gi|4826730 FK506 binding protein 12-rapamycin associated protein...    44   0.001
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ...    40   0.009
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro...    40   0.016
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap...    37   0.10 
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap...    37   0.10 
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap...    37   0.10 
gi|32455246 beta isoform of regulatory subunit A, protein phosph...    37   0.14 
gi|32455244 beta isoform of regulatory subunit A, protein phosph...    37   0.14 
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap...    36   0.23 
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    35   0.30 
gi|158631177 homeodomain leucine zipper protein [Homo sapiens]         35   0.30 
gi|55956788 nucleolin [Homo sapiens]                                   35   0.40 
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]           35   0.40 
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi...    35   0.40 
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    35   0.52 
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    35   0.52 
gi|23510381 transportin 1 isoform 2 [Homo sapiens]                     35   0.52 
gi|133925811 transportin 1 isoform 1 [Homo sapiens]                    35   0.52 
gi|239756451 PREDICTED: hypothetical protein XP_002344991 [Homo ...    34   0.68 
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]           34   0.68 
gi|239750982 PREDICTED: hypothetical protein XP_002347636 [Homo ...    34   0.68 
gi|239745387 PREDICTED: hypothetical protein XP_002343486 [Homo ...    34   0.68 
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       34   0.68 
gi|24797086 importin 5 [Homo sapiens]                                  34   0.68 
gi|21361399 alpha isoform of regulatory subunit A, protein phosp...    34   0.68 
gi|24430139 RNA polymerase II associated protein 1 [Homo sapiens]      34   0.68 

>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
          Length = 1119

 Score = 2179 bits (5647), Expect = 0.0
 Identities = 1119/1119 (100%), Positives = 1119/1119 (100%)

Query: 1    MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
            MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK
Sbjct: 1    MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60

Query: 61   NGEVQNLAVKWLGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVE 120
            NGEVQNLAVKWLGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVE
Sbjct: 61   NGEVQNLAVKWLGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVE 120

Query: 121  LADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDE 180
            LADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDE
Sbjct: 121  LADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDE 180

Query: 181  LRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFS 240
            LRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFS
Sbjct: 181  LRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFS 240

Query: 241  EQESEDEYSDDDDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVK 300
            EQESEDEYSDDDDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVK
Sbjct: 241  EQESEDEYSDDDDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVK 300

Query: 301  ADVFTAYIVLLRQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRAR 360
            ADVFTAYIVLLRQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRAR
Sbjct: 301  ADVFTAYIVLLRQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRAR 360

Query: 361  QGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAE 420
            QGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAE
Sbjct: 361  QGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAE 420

Query: 421  AFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAV 480
            AFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAV
Sbjct: 421  AFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAV 480

Query: 481  TLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKA 540
            TLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKA
Sbjct: 481  TLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKA 540

Query: 541  LTLVAVSPLQLDLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQ 600
            LTLVAVSPLQLDLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQ
Sbjct: 541  LTLVAVSPLQLDLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQ 600

Query: 601  AVLAELPALVNESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGV 660
            AVLAELPALVNESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGV
Sbjct: 601  AVLAELPALVNESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGV 660

Query: 661  LAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSA 720
            LAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSA
Sbjct: 661  LAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSA 720

Query: 721  ACPQEAASTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSP 780
            ACPQEAASTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSP
Sbjct: 721  ACPQEAASTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSP 780

Query: 781  SEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPY 840
            SEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPY
Sbjct: 781  SEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPY 840

Query: 841  AEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITA 900
            AEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITA
Sbjct: 841  AEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITA 900

Query: 901  VKFLISDQPHPIDPLLKSFIAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFK 960
            VKFLISDQPHPIDPLLKSFIAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFK
Sbjct: 901  VKFLISDQPHPIDPLLKSFIAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFK 960

Query: 961  HTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLAT 1020
            HTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLAT
Sbjct: 961  HTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLAT 1020

Query: 1021 LCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKS 1080
            LCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKS
Sbjct: 1021 LCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKS 1080

Query: 1081 PIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1119
            PIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS
Sbjct: 1081 PIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1119


>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
          Length = 1236

 Score = 2032 bits (5264), Expect = 0.0
 Identities = 1048/1072 (97%), Positives = 1048/1072 (97%), Gaps = 24/1072 (2%)

Query: 72   LGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPG 131
            LGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPG
Sbjct: 165  LGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPG 224

Query: 132  PRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEA 191
            PRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEA
Sbjct: 225  PRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEA 284

Query: 192  FLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDD 251
            FLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDD
Sbjct: 285  FLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDD 344

Query: 252  DDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLL 311
            DDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLL
Sbjct: 345  DDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLL 404

Query: 312  RQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELA 371
            RQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELA
Sbjct: 405  RQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELA 464

Query: 372  GVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLP 431
            GVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLP
Sbjct: 465  GVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLP 524

Query: 432  PVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD 491
            PVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD
Sbjct: 525  PVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD 584

Query: 492  QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQL 551
            QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQL
Sbjct: 585  QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQL 644

Query: 552  DLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVN 611
            DLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVN
Sbjct: 645  DLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVN 704

Query: 612  ESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQAL 671
            ESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQAL
Sbjct: 705  ESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQAL 764

Query: 672  VGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTAS 731
            VGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTAS
Sbjct: 765  VGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTAS 824

Query: 732  RLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYA 791
            RLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYA
Sbjct: 825  RLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYA 884

Query: 792  LGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR 851
            LGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR
Sbjct: 885  LGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR 944

Query: 852  CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHP 911
            CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHP
Sbjct: 945  CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHP 1004

Query: 912  IDPLLKSFI------------------------AVHNKPSLVRDLLDDILPLLYQETKIR 947
            IDPLLKSFI                        AVHNKPSLVRDLLDDILPLLYQETKIR
Sbjct: 1005 IDPLLKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIR 1064

Query: 948  RDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDI 1007
            RDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDI
Sbjct: 1065 RDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDI 1124

Query: 1008 RMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRA 1067
            RMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRA
Sbjct: 1125 RMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRA 1184

Query: 1068 VAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1119
            VAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS
Sbjct: 1185 VAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1236



 Score =  137 bits (345), Expect = 6e-32
 Identities = 72/73 (98%), Positives = 72/73 (98%)

Query: 1  MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
          MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK
Sbjct: 1  MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60

Query: 61 NGEVQNLAVKWLG 73
          NGEVQNLAVK LG
Sbjct: 61 NGEVQNLAVKCLG 73


>gi|21361794 TIP120 protein [Homo sapiens]
          Length = 1230

 Score = 1231 bits (3184), Expect = 0.0
 Identities = 618/1066 (57%), Positives = 808/1066 (75%), Gaps = 32/1066 (3%)

Query: 79   FHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSP 138
            FH S+L CLLPQL+SPRLAVRKR + ALGHL  +C   +FV+L +HLL  L       S 
Sbjct: 172  FHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKN---DSM 228

Query: 139  TAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPK 198
            +  RT IQC+ ++ RQAGHR+G +L++++PLV  FCN+DDDELRE C+QAFE+F+R+CPK
Sbjct: 229  STTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPK 288

Query: 199  EMGPHVPNVTSLCLQYIKHDPNYNYDS-DEDEEQMETEDSEFSEQESEDEYSDDDDMSWK 257
            E+ PHV  + ++CL+Y+ +DPNYNYD  DEDE  M+ +  +  +Q S+DEYSDDDDMSWK
Sbjct: 289  EVYPHVSTIINICLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWK 348

Query: 258  VRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPP 317
            VRRAAAKC+ A++S+R ++LP+F+ T++P LI RFKEREENVKADVF AY+ LL+QT+P 
Sbjct: 349  VRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPV 408

Query: 318  KGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGS 377
            + WL   +   Q  + L ML+ QVP +VKAL +Q+K++SV+ RQ CF++LTEL  VLPG+
Sbjct: 409  QSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGA 468

Query: 378  LAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACV 437
            L +H+PVLV GIIFSL D+SSSS +++DAL+ L  +L     + FHPH+  L+PPV+ACV
Sbjct: 469  LTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACV 528

Query: 438  ADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKER 497
             D FYKI +EAL+V Q+LV+ + PL +P   D  PY+ ++   T+ RL+A D+DQEVKER
Sbjct: 529  GDPFYKITSEALLVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKER 588

Query: 498  AISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPIL 557
            AISCMG ++ +LGD LG DL  TL + L+RL+NEITRL  +KALTL+A SPL++DL+P+L
Sbjct: 589  AISCMGQIICNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVL 648

Query: 558  AEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHV 617
             E + ILASFLRKNQRAL+L TL+ALD L ++   SL  + + AVL ELP L++ESDMHV
Sbjct: 649  GEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHV 708

Query: 618  AQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPP 677
            +Q+A+ FL T+ +  P+SL ++SG +L+EL+ L+RSPLL  G L+A   F QALV T   
Sbjct: 709  SQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTN 768

Query: 678  CVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDA 737
             + Y  L+ +LT PVY Q+       HKQ ++S+A+CVAAL+ ACP+E  +   + + D 
Sbjct: 769  NLGYMDLLRMLTGPVYSQST---ALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDV 825

Query: 738  RSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGA 797
            ++  S+  +++LA LSL EVG       Q ELK+V+LEA  SPSE+V++AASYALG +  
Sbjct: 826  KNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISV 885

Query: 798  GSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEE 857
            G+LP++LPF+L++I ++P+RQYLLLHSL+E + +A    LKPY E+IWALL + CE AEE
Sbjct: 886  GNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEE 945

Query: 858  GTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLK 917
            GTR VVAEC+GKL L++P  LLPRL+  L +G  + RS+V+TAVKF ISD P PIDPLLK
Sbjct: 946  GTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLK 1005

Query: 918  SFI------------------------AVHNKPSLVRDLLDDILPLLYQETKIRRDLIRE 953
            + I                        A HNKPSL+RDLLD +LP LY ETK+R++LIRE
Sbjct: 1006 NCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIRE 1065

Query: 954  VEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFI 1013
            VEMGPFKHTVDDGLD+RKAAFECMY+LL+SCL +LDI EFLNHVEDGLKDHYDI+MLTF+
Sbjct: 1066 VEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFL 1125

Query: 1014 MVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLT 1073
            M+ RL+TLCP+ VLQR+DRL+EPLRATCT KVKA SVKQEFEKQDELKRSAMRAVAALLT
Sbjct: 1126 MLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLT 1185

Query: 1074 IPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1119
            IPE  KSP+M++F SQI SNPELAA+FESIQKDS+S  + +SM+ S
Sbjct: 1186 IPEAEKSPLMSEFQSQISSNPELAAIFESIQKDSSST-NLESMDTS 1230


>gi|62460637 importin 4 [Homo sapiens]
          Length = 1081

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 147/594 (24%), Positives = 224/594 (37%), Gaps = 114/594 (19%)

Query: 47  RKVVKMLLRLLEDKN-GEVQNLA---------VKWLGVPLGAFHASLLHCLLPQL---SS 93
           R+V+ +LL  L+    G   +LA         V+ LG  +  +   L+ C+L  L   SS
Sbjct: 434 REVMPLLLAYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSS 493

Query: 94  PRLAVRKRAVGALGHLAAACSTDL---FVELADHLLDRLPGPRVPTSPTAIRTLIQCLGS 150
           PR   ++ AV ALG +A A    L   F  + +HL + L   R    P  I++L + LG 
Sbjct: 494 PR--AKELAVSALGAIATAAQASLLPYFPAIMEHLREFLLTGREDLQPVQIQSL-ETLGV 550

Query: 151 VGRQAGHRLGAHLDRLVPLVEDFCNL--------DDDELRESCLQAFEAFLRKCPKEMGP 202
           + R  G       + + PL E+ C L        DD +LR      F A      + + P
Sbjct: 551 LARAVG-------EPMRPLAEECCQLGLGLCDQVDDPDLRRCTYSLFAALSGLMGEGLAP 603

Query: 203 HVPNVTSLCLQYIKHD----PNYN-----------YDSDEDEEQM-----ETEDSEFSEQ 242
           H+  +T+L L  ++      P Y+            D +E+EE M     E +DSE S  
Sbjct: 604 HLEQITTLMLLSLRSTEGIVPQYDGSSSFLLFDDESDGEEEEELMDEDVEEEDDSEISGY 663

Query: 243 ESEDEYSDD-DDMSWKVRRAAAKCIAALISSRPDLLPD-FHCTLAPVLIRRFKEREENVK 300
             E+ + D+ +D    V   +     A +     +  + F     P L  R    E    
Sbjct: 664 SVENAFFDEKEDTCAAVGEISVNTSVAFLPYMESVFEEVFKLLECPHLNVRKAAHE---A 720

Query: 301 ADVFTAYIVLLRQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRAR 360
              F   +    Q+ P         EP        + R  VP  ++A+ R+      R R
Sbjct: 721 LGQFCCALHKACQSCP--------SEPNTAALQAALAR-VVPSYMQAVNRE------RER 765

Query: 361 QGCFSLLTELAGVL----------PGSLAEHMPVLVSGIIFSLA--------DRSSSSTI 402
           Q   ++L  L GVL          PG LAE   VL + +    A        +       
Sbjct: 766 QVVMAVLEALTGVLRSCGTLTLKPPGRLAELCGVLKAVLQRKTACQDTDEEEEEEDDDQA 825

Query: 403 RMDALAF------LQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVV--LQE 454
             DA+        +  L      ++F P     L P++ C       +A ++  V  L E
Sbjct: 826 EYDAMLLEHAGEAIPALAAAAGGDSFAPFFAGFL-PLLVCKTKQGCTVAEKSFAVGTLAE 884

Query: 455 LVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVGHLGDRLG 514
            ++ L             +V  +  V L+   A + D EV+  AI  MG L  H G    
Sbjct: 885 TIQGLGAA-------SAQFVSRLLPVLLS--TAQEADPEVRSNAIFGMGVLAEHGGHPAQ 935

Query: 515 DDLEPTLLL---LLDRLRNEITRLPAIKALT-LVAVSPLQLDLQPILAEALHIL 564
           +     L L   LL R R++  R     AL  L+  SP +     +LA  LH L
Sbjct: 936 EHFPKLLGLLFPLLARERHDRVRDNICGALARLLMASPTRKPEPQVLAALLHAL 989



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 58/253 (22%), Positives = 99/253 (39%), Gaps = 28/253 (11%)

Query: 510 GDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILA----EALHILA 565
           GD +   L P LL ++ +   + +++  ++   L A+     +LQP ++    E + +L 
Sbjct: 384 GDHIRQRLLPPLLQIVCKGLEDPSQV--VRNAALFALGQFSENLQPHISSYSREVMPLLL 441

Query: 566 SFLRKNQ--RALRLATLA-ALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAV 622
           ++L+         LA    AL+   ++ G  + P   + +   L  L N S     +LAV
Sbjct: 442 AYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAV 501

Query: 623 DFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYA 682
             L  +  A  ASL+     ++  L   L         L   E      + +       A
Sbjct: 502 SALGAIATAAQASLLPYFPAIMEHLREFL---------LTGREDLQPVQIQSLETLGVLA 552

Query: 683 KLISLLTAPVYEQAVDGGPGLHKQVFH-SLARCVAALSAACPQEAASTASRLVCDARSPH 741
           + +     P+ E+    G GL  QV    L RC  +L AA         S L+ +  +PH
Sbjct: 553 RAVGEPMRPLAEECCQLGLGLCDQVDDPDLRRCTYSLFAA--------LSGLMGEGLAPH 604

Query: 742 SSTGVKVLAFLSL 754
               +  L  LSL
Sbjct: 605 LEQ-ITTLMLLSL 616



 Score = 30.4 bits (67), Expect = 9.8
 Identities = 50/209 (23%), Positives = 82/209 (39%), Gaps = 36/209 (17%)

Query: 722 CPQEAASTASRLVCDARSPHS-STGVKVLAFLSLAEVGQVAGPGHQRELKAVLLE----A 776
           CPQ        L   + SP+    G+ VLA LS       AG   ++ L   LL+     
Sbjct: 350 CPQLMPMLEEAL--RSESPYQRKAGLLVLAVLS-----DGAGDHIRQRLLPPLLQIVCKG 402

Query: 777 LGSPSEDVRAAASYALGRVGAGSLP-------DFLPFLLEQIEAEPRRQYLLLHSLREAL 829
           L  PS+ VR AA +ALG+      P       + +P LL  +++ P       H L +A 
Sbjct: 403 LEDPSQVVRNAALFALGQFSENLQPHISSYSREVMPLLLAYLKSVPLGH---THHLAKAC 459

Query: 830 GAAQ------PDSLKPYAEDIWALLFQRCEG-AEEGTRGVVAECIGKLVLVNPSFLLP-- 880
            A +         ++PY  ++   + Q     +    + +    +G +     + LLP  
Sbjct: 460 YALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQASLLPYF 519

Query: 881 -----RLRKQLAAGRPHTRSTVITAVKFL 904
                 LR+ L  GR   +   I +++ L
Sbjct: 520 PAIMEHLREFLLTGREDLQPVQIQSLETL 548


>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
           [Homo sapiens]
          Length = 2549

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 85/381 (22%), Positives = 149/381 (39%), Gaps = 41/381 (10%)

Query: 562 HILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLA 621
           H+L+   ++ +R      L  L    +S+     P  +  + A LP    +   H  Q A
Sbjct: 419 HVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPP---KDFAHKRQKA 475

Query: 622 VDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDY 681
           +   ATV     + L    GP + + ++ L  P+L  G+  A    L  L    P     
Sbjct: 476 MQVDATVFTCI-SMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKD 534

Query: 682 AK--LISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARS 739
            +  L+ +L+  +  + +   PG+ K + H LA   +      P+ +   +  L      
Sbjct: 535 IQDGLLKMLSLVLMHKPLRH-PGMPKGLAHQLA---SPGLTTLPEASDVGSITLALRTLG 590

Query: 740 PHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEA------LGSPSEDVRAAASYALG 793
                G  +  F     V   A      E K + +EA      L +PS  + +  ++ + 
Sbjct: 591 SFEFEGHSLTQF-----VRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVS 645

Query: 794 RVGAGSLPDFLPFLLEQ--IEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR 851
           +     + D L  LL     + +P  +Y +L SL E       D+    AE++ AL    
Sbjct: 646 QTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERF-----DAHLAQAENLQALFVAL 700

Query: 852 CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVK--------F 903
            +   E  R +    +G+L  +NP+F++P LRK L         + I  +K         
Sbjct: 701 NDQVFE-IRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGH 759

Query: 904 LISDQPHPI----DPLLKSFI 920
           L+S+ P  I    +P+LK+ I
Sbjct: 760 LVSNAPRLIRPYMEPILKALI 780


>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
            [Homo sapiens]
          Length = 2671

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 129/598 (21%), Positives = 217/598 (36%), Gaps = 76/598 (12%)

Query: 344  VVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSS-TI 402
            V+  L     D  +  RQ    +   +    P +L E +P L   ++  LA   +   TI
Sbjct: 1885 VLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTI 1944

Query: 403  RMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPL 462
                L  L   LG +           +LP ++  + +      ++     Q +   L  +
Sbjct: 1945 AARTLGDLVRKLGEK-----------ILPEIIPILEEGLRSQKSDER---QGVCIGLSEI 1990

Query: 463  HRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLL 522
             +    D   Y  E S V  AR    D  +EV+E A      L   +G +  +D+ P LL
Sbjct: 1991 MKSTSRDAVLYFSE-SLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLL 2049

Query: 523  LLLDRLR------NEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKNQRALR 576
              LD         + + ++ AIK+  ++     +L   P+              N R L 
Sbjct: 2050 KQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPV--------------NTRVLA 2095

Query: 577  LATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQAQPASL 636
              +  A DAL +  G+ LP  AV   L E     +E  + +A      L+         +
Sbjct: 2096 FLSSVAGDALTRHLGVILP--AVMLALKEKLGTPDEQ-LEMANCQAVILSVEDDTGHRII 2152

Query: 637  VEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYEQA 696
            +E       +LL   RSP    G+  AA   L           DY   +  L + +    
Sbjct: 2153 IE-------DLLEATRSP--EVGMRQAAAIILNIYCSRSK--ADYTSHLRSLVSGLIRLF 2201

Query: 697  VDGGPGLHKQVFHSLARCVAALSAACPQ---EAASTASRLVCDARSPHSSTGV-----KV 748
             D  P + ++ + +L      L A       E      RL+ +        G       V
Sbjct: 2202 NDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGV 2261

Query: 749  LAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFLL 808
             + L +   G + G   Q+E  A   +ALG     +R  ++ AL           +  L 
Sbjct: 2262 TSILPVLREGVLTGSPEQKEEAA---KALGLV---IRLTSADALRPSVVSITGPLIRILG 2315

Query: 809  EQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIG 868
            ++     +   L   SL   L A    +LKP+   +     +  + +  G R   A+ +G
Sbjct: 2316 DRFSWNVKAALLETLSL---LLAKVGIALKPFLPQLQTTFTKALQDSNRGVRLKAADALG 2372

Query: 869  KL----VLVNPSF--LLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFI 920
            KL    + V+P F  LL  +R   A   P  R T++ A++F+I      +D +++  I
Sbjct: 2373 KLISIHIKVDPLFTELLNGIR---AMEDPGVRDTMLQALRFVIQGAGAKVDAVIRKNI 2427



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 54/233 (23%), Positives = 93/233 (39%), Gaps = 33/233 (14%)

Query: 341  VPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLAD----- 395
            V LV+ +L   L++ S R + G   LL  +A   P  L+  +P +V  +   L D     
Sbjct: 1495 VKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKV 1554

Query: 396  --------RSSSSTIRM-DALAFLQGLLG--TEPAEAFHPHLPILLPP------------ 432
                    R   S IR  + LA    LL   T+P+      L  LL              
Sbjct: 1555 QKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLA 1614

Query: 433  -VMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD 491
             +M  V  +F   + +   +  +++  ++ L   +  D  PY+  ++    A L   D  
Sbjct: 1615 LIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQK--DLAPYLPSVTPGLKASL--LDPV 1670

Query: 492  QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLV 544
             EV+  +   +G +V  +G+   +DL P L+  L   ++ + R  A + L  V
Sbjct: 1671 PEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEV 1723


>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
           protein homolog 1 [Homo sapiens]
          Length = 557

 Score = 39.7 bits (91), Expect = 0.016
 Identities = 20/36 (55%), Positives = 23/36 (63%), Gaps = 1/36 (2%)

Query: 218 DPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDD 253
           D  YNY+ DEDEE  E EDS   E+E ED+   DDD
Sbjct: 4   DEGYNYEFDEDEECSE-EDSGAEEEEDEDDDEPDDD 38


>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
           sapiens]
          Length = 594

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)

Query: 214 YIKHDPNYNYD-----SDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 268
           Y++H  N   +     SD DEE    ED E  E+E E E   +++ + +  + A  C A 
Sbjct: 241 YLRHQVNLRDELLQLYSDSDEED---EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAP 297

Query: 269 LISSRPDLLPDFHCTLAPVLIRRFKEREE 297
            + S+  LL   HC     L  + +  EE
Sbjct: 298 KLISQEALLHQHHCPQLEALQEKLRLLEE 326


>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
           sapiens]
          Length = 602

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)

Query: 214 YIKHDPNYNYD-----SDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 268
           Y++H  N   +     SD DEE    ED E  E+E E E   +++ + +  + A  C A 
Sbjct: 249 YLRHQVNLRDELLQLYSDSDEED---EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAP 305

Query: 269 LISSRPDLLPDFHCTLAPVLIRRFKEREE 297
            + S+  LL   HC     L  + +  EE
Sbjct: 306 KLISQEALLHQHHCPQLEALQEKLRLLEE 334


>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
           sapiens]
          Length = 619

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)

Query: 214 YIKHDPNYNYD-----SDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 268
           Y++H  N   +     SD DEE    ED E  E+E E E   +++ + +  + A  C A 
Sbjct: 241 YLRHQVNLRDELLQLYSDSDEED---EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAP 297

Query: 269 LISSRPDLLPDFHCTLAPVLIRRFKEREE 297
            + S+  LL   HC     L  + +  EE
Sbjct: 298 KLISQEALLHQHHCPQLEALQEKLRLLEE 326


>gi|32455246 beta isoform of regulatory subunit A, protein
           phosphatase 2 isoform a [Homo sapiens]
          Length = 601

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 10/137 (7%)

Query: 514 GDDLEPTLLLLLDRLRNEIT--RLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKN 571
           GDD    + +L+D LRNE    RL +IK L+ +A   L L ++   +E L  L   +   
Sbjct: 18  GDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIA---LALGVERTRSELLPFLTDTIYDE 74

Query: 572 QRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQA 631
              L    LA  + L    GL   P     +L  L  L    +  V   AV+ L  ++Q 
Sbjct: 75  DEVL----LALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQE 130

Query: 632 Q-PASLVEVSGPVLSEL 647
             P +L     P++  L
Sbjct: 131 HTPVALEAYFVPLVKRL 147


>gi|32455244 beta isoform of regulatory subunit A, protein
           phosphatase 2 isoform b [Homo sapiens]
          Length = 667

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 10/137 (7%)

Query: 514 GDDLEPTLLLLLDRLRNEIT--RLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKN 571
           GDD    + +L+D LRNE    RL +IK L+ +A   L L ++   +E L  L   +   
Sbjct: 18  GDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIA---LALGVERTRSELLPFLTDTIYDE 74

Query: 572 QRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQA 631
              L    LA  + L    GL   P     +L  L  L    +  V   AV+ L  ++Q 
Sbjct: 75  DEVL----LALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQE 130

Query: 632 Q-PASLVEVSGPVLSEL 647
             P +L     P++  L
Sbjct: 131 HTPVALEAYFVPLVKRL 147


>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
           sapiens]
          Length = 871

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 61/259 (23%), Positives = 107/259 (41%), Gaps = 38/259 (14%)

Query: 557 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 616
           LA A+ +L  F    + ALR A +  L+ +A        PSAV A   +L  L+ +S+  
Sbjct: 285 LAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLITDSNRS 339

Query: 617 VAQLAV-DFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTR 675
           +A LA+   L T +++    L++     +SE+    +  ++ A         + AL    
Sbjct: 340 IATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQA---------ISAL---- 386

Query: 676 PPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVC 735
             C  Y +  S++   +     D G   +K+   ++  C+ ++    P+   +  + L C
Sbjct: 387 --CQKYPRKHSVMMTFLSNMLRDDGGFEYKR---AIVDCIISIVEENPESKEAGLAHL-C 440

Query: 736 D--ARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAV--LLEALGSPSEDVRAAASYA 791
           +      H+    K+L  L         GP      K +  +   +   +E VRAAA  A
Sbjct: 441 EFIEDCEHTVLATKILHLLG------KEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSA 494

Query: 792 LGRVGAGS---LPDFLPFL 807
           L + GA +   LP  L  L
Sbjct: 495 LAKFGAQNESLLPSILVLL 513


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 35.4 bits (80), Expect = 0.30
 Identities = 15/49 (30%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 207 VTSLCLQYIKH--DPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDD 253
           + ++CL+ ++   D     D ++D++  + +D E  E+E E+E  DDDD
Sbjct: 119 IVNVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDD 167



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 224 DSDEDEEQMETEDSEFSEQESEDEYSDDDDMS 255
           D D+DE+  + ED E  E+E ED+  D +D +
Sbjct: 141 DDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFA 172


>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
          Length = 550

 Score = 35.4 bits (80), Expect = 0.30
 Identities = 13/31 (41%), Positives = 22/31 (70%)

Query: 224 DSDEDEEQMETEDSEFSEQESEDEYSDDDDM 254
           + +E+EE++  +D E  E+E ED+  DDDD+
Sbjct: 516 EEEEEEEELPEDDEEEEEEEEEDDDDDDDDV 546



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 15/28 (53%), Positives = 19/28 (67%)

Query: 226 DEDEEQMETEDSEFSEQESEDEYSDDDD 253
           DE+EE+ E E  E  E+E E+E  DDDD
Sbjct: 514 DEEEEEEEEELPEDDEEEEEEEEEDDDD 541



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 224 DSDEDEEQMETEDSEFSEQESEDEYSDDDD 253
           D +E+EE+ E  + +  E+E E+E  DDDD
Sbjct: 514 DEEEEEEEEELPEDDEEEEEEEEEDDDDDD 543



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 224 DSDEDEEQMETEDSEFSEQESEDEYSDDDD 253
           + +E+EE+   ED E  E+E E++  DDDD
Sbjct: 515 EEEEEEEEELPEDDEEEEEEEEEDDDDDDD 544


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 35.0 bits (79), Expect = 0.40
 Identities = 16/42 (38%), Positives = 26/42 (61%)

Query: 227 EDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 268
           ED ++ E +DSE  E++ EDE  D+D++     +AAA   A+
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS 184



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 171 EDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEE 230
           ED  + ++D+  E  ++   A  +K  K +     NV        + D + + D DED+E
Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE-DEDEEEDDEDEDDDDDEDDE 254

Query: 231 QMETEDSEFSEQESEDE 247
             + ED E  E+E E+E
Sbjct: 255 DDDDEDDEEEEEEEEEE 271


>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 487

 Score = 35.0 bits (79), Expect = 0.40
 Identities = 13/43 (30%), Positives = 25/43 (58%)

Query: 216 KHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKV 258
           K +   N + +EDEE+ + E+ E  E + ++E  DD+   W++
Sbjct: 320 KKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEDGDDEQSHWQL 362


>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
           sapiens]
          Length = 874

 Score = 35.0 bits (79), Expect = 0.40
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 557 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 616
           LA A+ +L  F    + ALR A +  L+ +A        PSAV A   +L  LV +S+  
Sbjct: 285 LAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLVTDSNRS 339

Query: 617 VAQLAV-DFLATVTQAQPASLVEVSGPVLSEL 647
           +A LA+   L T +++    L++     +SE+
Sbjct: 340 IATLAITTLLKTGSESSIDRLMKQISSFMSEI 371


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 34.7 bits (78), Expect = 0.52
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 193 LRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDD 252
           L + P   G   P  TS C  Y   D + + D +E+E++++ E  +  E E E+E  D D
Sbjct: 707 LAQHPHHRGLLSPGGTSCC--YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPD 764

Query: 253 D 253
           D
Sbjct: 765 D 765


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 34.7 bits (78), Expect = 0.52
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 193 LRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDD 252
           L + P   G   P  TS C  Y   D + + D +E+E++++ E  +  E E E+E  D D
Sbjct: 707 LAQHPHHRGLLSPGGTSCC--YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPD 764

Query: 253 D 253
           D
Sbjct: 765 D 765


>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
          Length = 890

 Score = 34.7 bits (78), Expect = 0.52
 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 34/154 (22%)

Query: 159 LGAHLDRLVP----LVEDFCNLDDDELRESCLQAFEAFLRK-----CPKEMGPHVPNVTS 209
           L   +DRL+P    +VE       D+     L+A E +L       C   +  H+P +  
Sbjct: 243 LEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIP 302

Query: 210 LCLQYIKHDPN----YNYDSDEDEE-------------------QMETEDSEFSEQESED 246
           + +  +K+          D +EDE                    Q   ED    E + +D
Sbjct: 303 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDD 362

Query: 247 EYSDDDDMS-WKVRRAAAKCIAALIS-SRPDLLP 278
           E  DDD +S W +R+ +A  +  L +  R +LLP
Sbjct: 363 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLP 396



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 26/166 (15%)

Query: 367 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 423
           L  LA V    L  H+  L+  ++F    +   S    +   A   +QG++         
Sbjct: 383 LDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMI--------- 433

Query: 424 PHLPILLPPVMACVADSFYKIAAEALVVLQELVR-ALWPLHRPRMLDPEPYVGEMSAVTL 482
           P+LP L+P ++ C++D   K A    +    L R A W + +P    P+ Y+  +    L
Sbjct: 434 PYLPELIPHLIQCLSD---KKALVRSITCWTLSRYAHWVVSQP----PDTYLKPLMTELL 486

Query: 483 ARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 528
            R+   D ++ V+E A S        L +    +L P L  +LD L
Sbjct: 487 KRI--LDSNKRVQEAACSAF----ATLEEEACTELVPYLAYILDTL 526


>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
          Length = 898

 Score = 34.7 bits (78), Expect = 0.52
 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 34/154 (22%)

Query: 159 LGAHLDRLVP----LVEDFCNLDDDELRESCLQAFEAFLRK-----CPKEMGPHVPNVTS 209
           L   +DRL+P    +VE       D+     L+A E +L       C   +  H+P +  
Sbjct: 251 LEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIP 310

Query: 210 LCLQYIKHDPN----YNYDSDEDEE-------------------QMETEDSEFSEQESED 246
           + +  +K+          D +EDE                    Q   ED    E + +D
Sbjct: 311 VLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDD 370

Query: 247 EYSDDDDMS-WKVRRAAAKCIAALIS-SRPDLLP 278
           E  DDD +S W +R+ +A  +  L +  R +LLP
Sbjct: 371 EIDDDDTISDWNLRKCSAAALDVLANVYRDELLP 404



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 26/166 (15%)

Query: 367 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 423
           L  LA V    L  H+  L+  ++F    +   S    +   A   +QG++         
Sbjct: 391 LDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMI--------- 441

Query: 424 PHLPILLPPVMACVADSFYKIAAEALVVLQELVR-ALWPLHRPRMLDPEPYVGEMSAVTL 482
           P+LP L+P ++ C++D   K A    +    L R A W + +P    P+ Y+  +    L
Sbjct: 442 PYLPELIPHLIQCLSD---KKALVRSITCWTLSRYAHWVVSQP----PDTYLKPLMTELL 494

Query: 483 ARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 528
            R+   D ++ V+E A S        L +    +L P L  +LD L
Sbjct: 495 KRI--LDSNKRVQEAACSAF----ATLEEEACTELVPYLAYILDTL 534


>gi|239756451 PREDICTED: hypothetical protein XP_002344991 [Homo
           sapiens]
          Length = 197

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 8/67 (11%)

Query: 202 PHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRA 261
           PH+ + TS C   +  +P+ + + + +EE+ + +D E      E+E  +DDD   ++RR+
Sbjct: 108 PHLFSATSGCTGRL--EPSESLELEPEEEEDDDDDDE------EEEELEDDDDEEELRRS 159

Query: 262 AAKCIAA 268
            A C AA
Sbjct: 160 FAGCRAA 166


>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 488

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 12/43 (27%), Positives = 24/43 (55%)

Query: 216 KHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKV 258
           K +     D +++EE+ + ED +  + E E+E  DD+   W++
Sbjct: 321 KEEEENEEDEEDEEEEKDEEDEDEEDDEDEEEDGDDEQSHWQL 363


>gi|239750982 PREDICTED: hypothetical protein XP_002347636 [Homo
           sapiens]
          Length = 206

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 8/67 (11%)

Query: 202 PHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRA 261
           PH+ + TS C   +  +P+ + + + +EE+ + +D E      E+E  +DDD   ++RR+
Sbjct: 117 PHLFSATSGCTGRL--EPSESLELEPEEEEDDDDDDE------EEEELEDDDDEEELRRS 168

Query: 262 AAKCIAA 268
            A C AA
Sbjct: 169 FAGCRAA 175


>gi|239745387 PREDICTED: hypothetical protein XP_002343486 [Homo
           sapiens]
          Length = 197

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 8/67 (11%)

Query: 202 PHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRA 261
           PH+ + TS C   +  +P+ + + + +EE+ + +D E      E+E  +DDD   ++RR+
Sbjct: 108 PHLFSATSGCTGRL--EPSESLELEPEEEEDDDDDDE------EEEELEDDDDEEELRRS 159

Query: 262 AAKCIAA 268
            A C AA
Sbjct: 160 FAGCRAA 166


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 14/34 (41%), Positives = 21/34 (61%)

Query: 220  NYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDD 253
            N + D  +DEE+ E ED E  +++ E E  D+DD
Sbjct: 2425 NEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDD 2458



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 15/35 (42%), Positives = 21/35 (60%)

Query: 218  DPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDD 252
            D + + D +E+EE+ E +D E  E E  DE  DDD
Sbjct: 2427 DEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDD 2461


>gi|24797086 importin 5 [Homo sapiens]
          Length = 1115

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 28/128 (21%), Positives = 49/128 (38%)

Query: 340 QVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSS 399
           Q P  +K L   +  ++V  R+    +     G+       ++ V+   ++  + D+   
Sbjct: 146 QWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHP 205

Query: 400 STIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRAL 459
           S   + A A    +L  E   A   H   LLP  +  V DS Y+     L  L E+   +
Sbjct: 206 SIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTV 265

Query: 460 WPLHRPRM 467
               RP +
Sbjct: 266 PKYLRPHL 273


>gi|21361399 alpha isoform of regulatory subunit A, protein
           phosphatase 2 [Homo sapiens]
          Length = 589

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 9/127 (7%)

Query: 514 GDDLEPTLLLLLDRLRNEIT--RLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKN 571
           GDD    + +L+D LRNE    RL +IK L+ +A   L L ++   +E L  L   +   
Sbjct: 6   GDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIA---LALGVERTRSELLPFLTDTIYDE 62

Query: 572 QRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQA 631
              L    LA  + L     L   P  V  +L  L +L    +  V   AV+ L  ++  
Sbjct: 63  DEVL----LALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHE 118

Query: 632 QPASLVE 638
              S +E
Sbjct: 119 HSPSDLE 125


>gi|24430139 RNA polymerase II associated protein 1 [Homo sapiens]
          Length = 1393

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 80/343 (23%), Positives = 121/343 (35%), Gaps = 44/343 (12%)

Query: 549  LQLDLQPILAEALHILASFLRKNQ-RALRLATLAALDALAQSQGLSLPPSAVQAVLAELP 607
            L  +L P+L  AL ++   L  +  + L +  +A+L  L     L+   +  + +     
Sbjct: 690  LYRELYPVLMRALQVVPRELSTHPPQPLSMQRIASLLTLLTQLTLAAGSTPAETI----- 744

Query: 608  ALVNESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLL-------PAGV 660
                 SD   A L+    + VT  Q + L  +  P L + L+LL  P +       P   
Sbjct: 745  -----SDSAEASLSAT-PSLVTWTQVSGLQPLVEPCLRQTLKLLSRPEMWRAVGPVPVAC 798

Query: 661  LAAAEGFLQALVGTRPPCV-----DYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCV 715
            L     + QA       C      D  +L   L  P+  Q   G       ++ SL  C 
Sbjct: 799  LLFLGAYYQAWSQQPSSCPEDWLQDMQRLSEELLLPLLSQPTLGS------LWDSLRHCS 852

Query: 716  AA---LSAACPQEAASTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQ--RELK 770
                 LS     EA  +   L C    P  S       F  L  +  +     Q  + L 
Sbjct: 853  LLCNPLSCVPALEAPPSLVSLGCSGGCPRLSLAGSASPFPFLTALLSLLNTLAQIHKGLC 912

Query: 771  AVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALG 830
              L   L +P        +Y L  V  G+ P   PF    +  E   QYL L +L +   
Sbjct: 913  GQLAAILAAPG-----LQNYFLQCVAPGAAPHLTPFSAWALRHEYHLQYLAL-ALAQKAA 966

Query: 831  AAQP---DSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKL 870
            A QP        Y     ALL +   G+E  T  ++  C+ +L
Sbjct: 967  ALQPLPATHAALYHGMALALLSRLLPGSEYLTHELLLSCVFRL 1009



 Score = 30.4 bits (67), Expect = 9.8
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 4/82 (4%)

Query: 1015 VARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTI 1074
            +ARL  + P  +LQ   RL+  L  +  A +++ S  QE   +   +       +A +T 
Sbjct: 232  IARLQAMAPEEILQEQQRLLAQLDPSLVAFLRSHSHTQEQTGETASEEQRPGGPSANVTK 291

Query: 1075 PEVGKSPIMADFSSQIRSNPEL 1096
             E    P+M+ F+S+ R   +L
Sbjct: 292  EE----PLMSAFASEPRKRDKL 309


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,796,153
Number of Sequences: 37866
Number of extensions: 1903214
Number of successful extensions: 10647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 9316
Number of HSP's gapped (non-prelim): 958
length of query: 1119
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1006
effective length of database: 13,968,660
effective search space: 14052471960
effective search space used: 14052471960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.