Guide to the Human Genome
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Search of human proteins with 112382226

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
         (1012 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]        2109   0.0  
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]        2109   0.0  
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]        2109   0.0  
gi|55750053 atrophin-1 [Homo sapiens]                                 709   0.0  
gi|55750041 atrophin-1 [Homo sapiens]                                 709   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   154   5e-37
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...   147   6e-35
gi|163965366 nascent polypeptide-associated complex alpha subuni...   147   6e-35
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   138   2e-32
gi|47132519 Ras association and pleckstrin homology domains 1 is...   136   9e-32
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  135   3e-31
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   135   3e-31
gi|160707881 formin 2 [Homo sapiens]                                  132   1e-30
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...   132   2e-30
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  130   6e-30
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  130   6e-30
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    124   4e-28
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...   122   2e-27
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                115   2e-25
gi|116284392 mucin 2 precursor [Homo sapiens]                         115   2e-25
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   112   1e-24
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...   111   4e-24
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...   111   4e-24
gi|150417989 cyclin K isoform 1 [Homo sapiens]                        111   4e-24
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...   110   9e-24
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]             108   2e-23
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                107   4e-23
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]      105   2e-22
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s...   104   4e-22
gi|151301053 RNA binding motif protein 33 [Homo sapiens]              104   4e-22

>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 2109 bits (5465), Expect = 0.0
 Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)

Query: 1    MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP 60
            MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP
Sbjct: 1    MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP 60

Query: 61   SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI 120
            SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI
Sbjct: 61   SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI 120

Query: 121  SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 180
            SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML
Sbjct: 121  SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 180

Query: 181  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240
            QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP
Sbjct: 181  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240

Query: 241  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
            VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP
Sbjct: 241  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300

Query: 301  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 360
            HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR
Sbjct: 301  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 360

Query: 361  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420
            EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS
Sbjct: 361  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420

Query: 421  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 480
            LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF
Sbjct: 421  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 480

Query: 481  AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540
            AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK
Sbjct: 481  AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540

Query: 541  EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL 600
            EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL
Sbjct: 541  EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL 600

Query: 601  AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 660
            AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE
Sbjct: 601  AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 660

Query: 661  GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720
            GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF
Sbjct: 661  GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720

Query: 721  YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 780
            YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL
Sbjct: 721  YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 780

Query: 781  DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 840
            DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD
Sbjct: 781  DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 840

Query: 841  RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 900
            RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP
Sbjct: 841  RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 900

Query: 901  LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA 960
            LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA
Sbjct: 901  LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA 960

Query: 961  HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012
            HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL
Sbjct: 961  HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 2109 bits (5465), Expect = 0.0
 Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)

Query: 1    MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP 60
            MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP
Sbjct: 555  MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP 614

Query: 61   SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI 120
            SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI
Sbjct: 615  SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI 674

Query: 121  SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 180
            SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML
Sbjct: 675  SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 734

Query: 181  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240
            QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP
Sbjct: 735  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794

Query: 241  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
            VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP
Sbjct: 795  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854

Query: 301  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 360
            HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR
Sbjct: 855  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 914

Query: 361  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420
            EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS
Sbjct: 915  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974

Query: 421  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 480
            LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF
Sbjct: 975  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 1034

Query: 481  AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540
            AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK
Sbjct: 1035 AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 1094

Query: 541  EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL 600
            EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL
Sbjct: 1095 EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL 1154

Query: 601  AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 660
            AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE
Sbjct: 1155 AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 1214

Query: 661  GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720
            GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF
Sbjct: 1215 GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274

Query: 721  YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 780
            YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL
Sbjct: 1275 YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 1334

Query: 781  DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 840
            DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD
Sbjct: 1335 DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 1394

Query: 841  RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 900
            RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP
Sbjct: 1395 RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 1454

Query: 901  LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA 960
            LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA
Sbjct: 1455 LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA 1514

Query: 961  HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012
            HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL
Sbjct: 1515 HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1566



 Score = 37.0 bits (84), Expect = 0.094
 Identities = 14/36 (38%), Positives = 27/36 (75%)

Query: 627 EREREKEKEKEREREREREREAERAAKASSSAHEGR 662
           +++++K+KEK+R+R+R+RERE    A+ S ++   R
Sbjct: 4   DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRR 39



 Score = 33.9 bits (76), Expect = 0.80
 Identities = 16/43 (37%), Positives = 29/43 (67%), Gaps = 5/43 (11%)

Query: 624 AREEREREKEKEKERERERERE-----REAERAAKASSSAHEG 661
           A ++++++KEK+++R+R+RERE     RE+E +    S   EG
Sbjct: 3   ADKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEG 45


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 2109 bits (5465), Expect = 0.0
 Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)

Query: 1    MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP 60
            MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP
Sbjct: 555  MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSP 614

Query: 61   SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI 120
            SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI
Sbjct: 615  SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEI 674

Query: 121  SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 180
            SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML
Sbjct: 675  SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 734

Query: 181  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240
            QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP
Sbjct: 735  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794

Query: 241  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
            VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP
Sbjct: 795  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854

Query: 301  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 360
            HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR
Sbjct: 855  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 914

Query: 361  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420
            EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS
Sbjct: 915  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974

Query: 421  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 480
            LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF
Sbjct: 975  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 1034

Query: 481  AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540
            AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK
Sbjct: 1035 AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 1094

Query: 541  EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL 600
            EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL
Sbjct: 1095 EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPL 1154

Query: 601  AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 660
            AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE
Sbjct: 1155 AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 1214

Query: 661  GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720
            GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF
Sbjct: 1215 GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274

Query: 721  YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 780
            YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL
Sbjct: 1275 YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 1334

Query: 781  DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 840
            DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD
Sbjct: 1335 DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 1394

Query: 841  RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 900
            RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP
Sbjct: 1395 RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 1454

Query: 901  LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA 960
            LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA
Sbjct: 1455 LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAA 1514

Query: 961  HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012
            HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL
Sbjct: 1515 HQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1566



 Score = 37.0 bits (84), Expect = 0.094
 Identities = 14/36 (38%), Positives = 27/36 (75%)

Query: 627 EREREKEKEKEREREREREREAERAAKASSSAHEGR 662
           +++++K+KEK+R+R+R+RERE    A+ S ++   R
Sbjct: 4   DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRR 39



 Score = 33.9 bits (76), Expect = 0.80
 Identities = 16/43 (37%), Positives = 29/43 (67%), Gaps = 5/43 (11%)

Query: 624 AREEREREKEKEKERERERERE-----REAERAAKASSSAHEG 661
           A ++++++KEK+++R+R+RERE     RE+E +    S   EG
Sbjct: 3   ADKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEG 45


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score =  709 bits (1830), Expect = 0.0
 Identities = 451/937 (48%), Positives = 531/937 (56%), Gaps = 126/937 (13%)

Query: 158  SPSIPSPQDNESDSDSSAQQQMLQAQPPA--LQAPTGVTPAPSSAPPGTPQLPTPGPTP- 214
            +P++P P      +++SA    L AQP    L +P  +       PPG  + PT  P+P 
Sbjct: 298  TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357

Query: 215  ------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP-- 266
                  S+   PP   P +S + +   A ++    +            P  PH  P P  
Sbjct: 358  SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417

Query: 267  ---SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ----HPGPPQPFG 319
               S  PP         QPS PS A   +  QGPP P     G LL     HPGP     
Sbjct: 418  LSVSNQPPKYT------QPSLPSQA---VWSQGPPPPPPY--GRLLANSNAHPGP----- 461

Query: 320  LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPH-- 373
             PP  S G       P + + H   Q    Q   Q QQ  ++Q      PP P A PH  
Sbjct: 462  FPP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519

Query: 374  ------------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421
                        + P   +  P  P P AH  PPH      +S      PP +    SS 
Sbjct: 520  EGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH--SQVSYSQAGPNGPPVSSSSNSSS 576

Query: 422  STHHP--PSAHPPPLQLMPQSQPLPSSP-------------------AQPPGLTQSQNLP 460
            ST     P +HP P Q  PQ  P P  P                   + P G   +    
Sbjct: 577  STSQGSYPCSHPSPSQ-GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635

Query: 461  PPPASH--PPTGLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPAGPGTS---- 511
            PPP     P  G ++ A  P +      PG PP     TPP    TS PPAGPGT     
Sbjct: 636  PPPYGKRAPSPGAYKTATPPGYK-----PGSPPSFRTGTPPGYRGTS-PPAGPGTFKPGS 689

Query: 512  ---AQPPCSGAAASG------GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562
                  P   A  SG         A  S  PL   QIK+E  ++ E PESP PP RSPSP
Sbjct: 690  PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749

Query: 563  EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQ 622
             P VVD PSHASQSARF KHLDRG+NSCAR+DLYF+PL GSKLAKKR + +EK +REAEQ
Sbjct: 750  PPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQ 809

Query: 623  KAREEREREKEKEKEREREREREREAERAAKASSSAHEGR--LSDPQLSGPGHMRPSFEP 680
            +AREE+ERE+E+E+E+ERERE+ERE ER+ K    A EGR  +  P L GP   RP FE 
Sbjct: 810  RAREEKEREREREREKEREREKERELERSVKL---AQEGRAPVECPSL-GPVPHRPPFE- 864

Query: 681  PPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDP-LLAYHMPGLY 739
            P + +A VPPY+GPDTPALRTLSEYARPHVMSP NRNHPFY+PL   DP LL Y++P LY
Sbjct: 865  PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALY 924

Query: 740  NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANP-MEHFARHSA 798
            + DP  RE        RERE RER+LR+R+KPGFEVKP EL+PLH    P ++ F RH  
Sbjct: 925  SSDPAARE--------REREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976

Query: 799  LTIPP-TAGPHPFASFHPGLNPLERERLAL-AGPQLRPEMSYPDRLAAERIHAERMASLT 856
            L + P   G HPF  FHP L PLERERLAL AGP LRP+MSY +RLAAER HAER+A+L 
Sbjct: 977  LALQPGPPGLHPF-PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALG 1035

Query: 857  SDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPY 916
            +DPLARLQM NVTPHHHQHSHIHSHLHLHQQD +H  SA  VHPL+DPL +G HL R PY
Sbjct: 1036 NDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASAS-VHPLIDPLASGSHLTRIPY 1094

Query: 917  PPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRL 976
            P GTLPNPLL  P HE+E+LRH +F  PY RDLP ++  PMSAAHQLQAMHAQSAELQRL
Sbjct: 1095 PAGTLPNPLLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153

Query: 977  AME-QQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012
            A+E QQWLH H  +H   LP+QEDYYS LKKE DK L
Sbjct: 1154 ALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190



 Score =  235 bits (600), Expect = 1e-61
 Identities = 224/676 (33%), Positives = 283/676 (41%), Gaps = 145/676 (21%)

Query: 18  MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 77
           M+TR+++ SMS +RSGRKK+   P        E++RS GR SP   STSS+D KAE  ++
Sbjct: 1   MKTRQNKDSMS-MRSGRKKEAPGP-------REELRSRGRASPGGVSTSSSDGKAEKSRQ 52

Query: 78  SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDS 136
           +AKK + E +S  K NK+ R +  S++E  +  + KKTKT QE+ RP SPS+ +  S D 
Sbjct: 53  TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--SLDG 110

Query: 137 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ--------PPALQ 188
           RS+ND+GSSDP+DIDQDNRSTSPSI SP   E+DSDSS+      A+        PP+ Q
Sbjct: 111 RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQ 170

Query: 189 AP--------------TGVTP----------------APSSAPPGTPQLPTPGPTPSATA 218
            P                VTP                AP  APP  PQL  PG T    +
Sbjct: 171 PPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL-YPGGTGGVLS 229

Query: 219 VPPQGSPTASQA-----PN---QPQAPTAPVPHTHIQQAPALHPQRPPS----------- 259
            PP G      A     PN   Q   PT P+       A    P +PP+           
Sbjct: 230 GPPMGPKGGGAASSVGGPNGGKQHPPPTTPI-SVSSSGASGAPPTKPPTTPVGGGNLPSA 288

Query: 260 ------PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313
                 PH  P+  P P L+PL  ++  P  P     PL G   P PH++  G     PG
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASP--PGLGAQPLPGH-LPSPHAMGQGMGGLPPG 345

Query: 314 P-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
           P       P P  LPP +S   AP    P ++   +S    +S S+  S   P   P   
Sbjct: 346 PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP--FPASQ 403

Query: 367 APLAMPHIKPPPTT-----PIPQLPAPQAHKHPPHLSGPSP------FSMNANLPPPPAL 415
           A  + PH  PPPT+       P+   P          GP P         N+N  P P  
Sbjct: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFP 463

Query: 416 KPLSSLSTHHPP-SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS--HPPTG-- 470
               + ST HPP S H    Q   Q Q       Q        + PPPP +  HP  G  
Sbjct: 464 PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGS 523

Query: 471 ---LHQVAPQPPFAQ-HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI 526
               H  A  P      P+ PG  P   PP     S   AGP     PP S ++ S  S 
Sbjct: 524 SHHAHPYAMSPSLGSLRPYPPG--PAHLPPPHSQVSYSQAGPN---GPPVSSSSNSSSST 578

Query: 527 AGGS-SC-----------------PLPTVQIKEEALDD-----AEEP-----ESPPPPP- 557
           + GS  C                 P+PTV      L       A  P      SPP PP 
Sbjct: 579 SQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638

Query: 558 ---RSPSPEPTVVDTP 570
              R+PSP      TP
Sbjct: 639 YGKRAPSPGAYKTATP 654


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score =  709 bits (1830), Expect = 0.0
 Identities = 451/937 (48%), Positives = 531/937 (56%), Gaps = 126/937 (13%)

Query: 158  SPSIPSPQDNESDSDSSAQQQMLQAQPPA--LQAPTGVTPAPSSAPPGTPQLPTPGPTP- 214
            +P++P P      +++SA    L AQP    L +P  +       PPG  + PT  P+P 
Sbjct: 298  TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357

Query: 215  ------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP-- 266
                  S+   PP   P +S + +   A ++    +            P  PH  P P  
Sbjct: 358  SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417

Query: 267  ---SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ----HPGPPQPFG 319
               S  PP         QPS PS A   +  QGPP P     G LL     HPGP     
Sbjct: 418  LSVSNQPPKYT------QPSLPSQA---VWSQGPPPPPPY--GRLLANSNAHPGP----- 461

Query: 320  LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPH-- 373
             PP  S G       P + + H   Q    Q   Q QQ  ++Q      PP P A PH  
Sbjct: 462  FPP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519

Query: 374  ------------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421
                        + P   +  P  P P AH  PPH      +S      PP +    SS 
Sbjct: 520  EGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH--SQVSYSQAGPNGPPVSSSSNSSS 576

Query: 422  STHHP--PSAHPPPLQLMPQSQPLPSSP-------------------AQPPGLTQSQNLP 460
            ST     P +HP P Q  PQ  P P  P                   + P G   +    
Sbjct: 577  STSQGSYPCSHPSPSQ-GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635

Query: 461  PPPASH--PPTGLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPAGPGTS---- 511
            PPP     P  G ++ A  P +      PG PP     TPP    TS PPAGPGT     
Sbjct: 636  PPPYGKRAPSPGAYKTATPPGYK-----PGSPPSFRTGTPPGYRGTS-PPAGPGTFKPGS 689

Query: 512  ---AQPPCSGAAASG------GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562
                  P   A  SG         A  S  PL   QIK+E  ++ E PESP PP RSPSP
Sbjct: 690  PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749

Query: 563  EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQ 622
             P VVD PSHASQSARF KHLDRG+NSCAR+DLYF+PL GSKLAKKR + +EK +REAEQ
Sbjct: 750  PPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQ 809

Query: 623  KAREEREREKEKEKEREREREREREAERAAKASSSAHEGR--LSDPQLSGPGHMRPSFEP 680
            +AREE+ERE+E+E+E+ERERE+ERE ER+ K    A EGR  +  P L GP   RP FE 
Sbjct: 810  RAREEKEREREREREKEREREKERELERSVKL---AQEGRAPVECPSL-GPVPHRPPFE- 864

Query: 681  PPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDP-LLAYHMPGLY 739
            P + +A VPPY+GPDTPALRTLSEYARPHVMSP NRNHPFY+PL   DP LL Y++P LY
Sbjct: 865  PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALY 924

Query: 740  NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANP-MEHFARHSA 798
            + DP  RE        RERE RER+LR+R+KPGFEVKP EL+PLH    P ++ F RH  
Sbjct: 925  SSDPAARE--------REREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976

Query: 799  LTIPP-TAGPHPFASFHPGLNPLERERLAL-AGPQLRPEMSYPDRLAAERIHAERMASLT 856
            L + P   G HPF  FHP L PLERERLAL AGP LRP+MSY +RLAAER HAER+A+L 
Sbjct: 977  LALQPGPPGLHPF-PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALG 1035

Query: 857  SDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPY 916
            +DPLARLQM NVTPHHHQHSHIHSHLHLHQQD +H  SA  VHPL+DPL +G HL R PY
Sbjct: 1036 NDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASAS-VHPLIDPLASGSHLTRIPY 1094

Query: 917  PPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRL 976
            P GTLPNPLL  P HE+E+LRH +F  PY RDLP ++  PMSAAHQLQAMHAQSAELQRL
Sbjct: 1095 PAGTLPNPLLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153

Query: 977  AME-QQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012
            A+E QQWLH H  +H   LP+QEDYYS LKKE DK L
Sbjct: 1154 ALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190



 Score =  235 bits (600), Expect = 1e-61
 Identities = 224/676 (33%), Positives = 283/676 (41%), Gaps = 145/676 (21%)

Query: 18  MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 77
           M+TR+++ SMS +RSGRKK+   P        E++RS GR SP   STSS+D KAE  ++
Sbjct: 1   MKTRQNKDSMS-MRSGRKKEAPGP-------REELRSRGRASPGGVSTSSSDGKAEKSRQ 52

Query: 78  SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDS 136
           +AKK + E +S  K NK+ R +  S++E  +  + KKTKT QE+ RP SPS+ +  S D 
Sbjct: 53  TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--SLDG 110

Query: 137 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ--------PPALQ 188
           RS+ND+GSSDP+DIDQDNRSTSPSI SP   E+DSDSS+      A+        PP+ Q
Sbjct: 111 RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQ 170

Query: 189 AP--------------TGVTP----------------APSSAPPGTPQLPTPGPTPSATA 218
            P                VTP                AP  APP  PQL  PG T    +
Sbjct: 171 PPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL-YPGGTGGVLS 229

Query: 219 VPPQGSPTASQA-----PN---QPQAPTAPVPHTHIQQAPALHPQRPPS----------- 259
            PP G      A     PN   Q   PT P+       A    P +PP+           
Sbjct: 230 GPPMGPKGGGAASSVGGPNGGKQHPPPTTPI-SVSSSGASGAPPTKPPTTPVGGGNLPSA 288

Query: 260 ------PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313
                 PH  P+  P P L+PL  ++  P  P     PL G   P PH++  G     PG
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASP--PGLGAQPLPGH-LPSPHAMGQGMGGLPPG 345

Query: 314 P-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
           P       P P  LPP +S   AP    P ++   +S    +S S+  S   P   P   
Sbjct: 346 PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP--FPASQ 403

Query: 367 APLAMPHIKPPPTT-----PIPQLPAPQAHKHPPHLSGPSP------FSMNANLPPPPAL 415
           A  + PH  PPPT+       P+   P          GP P         N+N  P P  
Sbjct: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFP 463

Query: 416 KPLSSLSTHHPP-SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS--HPPTG-- 470
               + ST HPP S H    Q   Q Q       Q        + PPPP +  HP  G  
Sbjct: 464 PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGS 523

Query: 471 ---LHQVAPQPPFAQ-HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI 526
               H  A  P      P+ PG  P   PP     S   AGP     PP S ++ S  S 
Sbjct: 524 SHHAHPYAMSPSLGSLRPYPPG--PAHLPPPHSQVSYSQAGPN---GPPVSSSSNSSSST 578

Query: 527 AGGS-SC-----------------PLPTVQIKEEALDD-----AEEP-----ESPPPPP- 557
           + GS  C                 P+PTV      L       A  P      SPP PP 
Sbjct: 579 SQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638

Query: 558 ---RSPSPEPTVVDTP 570
              R+PSP      TP
Sbjct: 639 YGKRAPSPGAYKTATP 654


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score =  154 bits (388), Expect = 5e-37
 Identities = 142/437 (32%), Positives = 178/437 (40%), Gaps = 50/437 (11%)

Query: 170 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ 229
           ++ SS     LQ  P +L  P  +   PS APP       P  TP     PP  +P   Q
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLET-PPCPAPCPLQ 570

Query: 230 APNQPQAPTAPVPHTHIQQAPALHPQRPPS-PHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288
           AP  P     P   + I   P   PQ PP+   PP    P PPL PL     Q + P  A
Sbjct: 571 APPSPLTTPPPETPSSIATPP---PQAPPALASPPLQGLPSPPLSPLATPPPQ-APPXLA 626

Query: 289 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL----------PPQASQGQAPLGTSPAAA 338
            PPL  Q PP P +      L  P P  P  L          PP +   QAP   SP A+
Sbjct: 627 LPPL--QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPAS 682

Query: 339 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 398
            P +    P SQ+      PP +  +PP+P A P + P  T P PQ P P A   PP   
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPP-PQAPPPLAA--PPLQV 737

Query: 399 GPSPFS---MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---AQPPG 452
            PSP +   M+ +  PPP + PL +      P + P  L + P ++P P +P   A PP 
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP- 796

Query: 453 LTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSA 512
               Q LP PPAS P              Q PF P    P++P   P    PP       
Sbjct: 797 ---LQALPSPPASFP-------------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 513 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSH 572
           Q P S  A+           P P   +    L  A  P  PPPP RSPS   +  D   H
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900

Query: 573 ASQSARFYKHLDRGYNS 589
           +S +    + L RGY+S
Sbjct: 901 SSSATSTPEEL-RGYDS 916



 Score =  116 bits (290), Expect = 1e-25
 Identities = 246/990 (24%), Positives = 326/990 (32%), Gaps = 161/990 (16%)

Query: 53  RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 112
           RS+G +S + AS      + E     A   K  +  P+ S  R     AS T        
Sbjct: 81  RSAGTSSRNPASRPPASGRGER----APPAKNTSPGPVSSPGR-----ASGTTRPGPLGQ 131

Query: 113 KKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 172
           K  +   IS   + + G+   +  RS    G+       +D    +P  PSP        
Sbjct: 132 KGLR---ISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAMARRSRA 182

Query: 173 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG--------- 223
           +  +  + +  P A   P   T  P  +     +  T  P+P+A   P  G         
Sbjct: 183 AGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 224 ------SPTASQAPNQPQA---PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
                 +P +S A + P A   P AP  H    +   L   RPP    PP     P L P
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQV-TPPRKDAAPALGP 298

Query: 275 LTGSAGQPSAPSHAQ----PPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQG 327
           L+ S     +PS  +    PP      P P +L   P L  P    PP P   PP     
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP-SAPPSLQTL 357

Query: 328 QAPLGTSPAAAYPHTS---LQLPASQSALQSQQPPR-----EQPLPPAPLAMPHIKPPPT 379
            +P  T P+ A P  +   +Q P S   +   Q P          PP+PLA+  ++   +
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 380 TPIPQLPAPQA------HKHPPHLSGPS----------PFSMNANLP--PP------PAL 415
              P L A  +       +    L+ PS          P     +LP  PP      PA+
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477

Query: 416 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPAS---HPP 468
            PLSS  T HP  A        PQ+ PL SS   PP  TQS   PP    PPAS    P 
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQA-PL-SSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535

Query: 469 TGLHQVAPQP----------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 518
             L  +AP P          P  + P  P  P P+  P  P T+ PP  P + A PP   
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPSPLTTPPPETPSSIATPPPQA 594

Query: 519 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEP--------ESPPPPPRSPSPEPTVVDTP 570
             A       G    LP+  +   A    + P        ++PP PP SP   P    +P
Sbjct: 595 PPALASPPLQG----LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650

Query: 571 SHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 630
              +  A                   F P A   ++       +     A    +     
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710

Query: 631 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTT---IAA 687
                         +     AA           S P       M PS  PPP     +AA
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP-------MSPSATPPPRVPPLLAA 763

Query: 688 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 747
            P  + P  PA   +S  A+P   +P         P   T PL A   P      P    
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAP---------PALATPPLQALPSP------PASFP 808

Query: 748 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 807
            +          +          P     P    P  P A+P     R      PPT GP
Sbjct: 809 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-----PPTPGP 863

Query: 808 HPFASFHPGLNPLERERLALA-GPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMF 866
               S         R  LALA GP   P  S    L+   + A   +S TS P   L+ +
Sbjct: 864 DTSVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP-EELRGY 914

Query: 867 NVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 926
           +  P     +       L    P    S GP  PL      G   A  P+PP T P    
Sbjct: 915 DSGPEGGAAASPPPDAELAACHPA-AWSRGPAPPLA---FRGAPGAPLPWPPATGPGSAD 970

Query: 927 GQ-PPHEHEMLRHPVFGTPYPRDL-PGAIP 954
           G    +E E    P   TP P  L PG  P
Sbjct: 971 GLCTIYETE---GPESATPAPGALDPGPSP 997



 Score =  115 bits (288), Expect = 2e-25
 Identities = 143/470 (30%), Positives = 168/470 (35%), Gaps = 140/470 (29%)

Query: 185  PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP---NQPQAPTAPV 241
            P L+ P    P P  APP +P    P  TPS+ A PP  +P A  +P     P  P +P+
Sbjct: 556  PHLETPPCPAPCPLQAPP-SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614

Query: 242  PHTHIQQAP--ALHP-QRPPSPHPPP-------------------------HPSPHPPLQ 273
                 Q  P  AL P Q PPSP   P                          P P PP+Q
Sbjct: 615  ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 274  -PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS---QGQA 329
             P +  A  P +PS A PP   Q PP   SL A PL   P PP    + P A+   Q   
Sbjct: 675  APFSPPASPPVSPS-ATPP--SQAPP---SLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728

Query: 330  PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL-----------PPAPLAM-PHIKPP 377
            PL   P    P      P S SA     PPR  PL           PPA L M P  KPP
Sbjct: 729  PLAAPPLQVPPSPPASPPMSPSATP---PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785

Query: 378  PTTPIPQLPAP--QAHKHPP-HLSGPSPFSMNANLP------PPPALKP-LSSLSTHHPP 427
            P  P P L  P  QA   PP    G +PFS +A+LP      PPP   P L++     PP
Sbjct: 786  PQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844

Query: 428  SAHPPPLQLMPQSQPLPSSPAQPPG----LTQSQNLPPPPASHPPTGLH----------- 472
            S    P    P+  P P       G    L  +   PPPP+  P + L            
Sbjct: 845  SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904

Query: 473  -----------------QVAPQPPFAQ----HPFV--------------PGGPPPITPPT 497
                               A  PP A+    HP                PG P P  P T
Sbjct: 905  TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 964

Query: 498  --------C-------PSTSTPPAG-------PGTSAQPPCSGAAASGGS 525
                    C       P ++TP  G       PGTS     +GA A   S
Sbjct: 965  GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 200/831 (24%), Positives = 265/831 (31%), Gaps = 146/831 (17%)

Query: 184 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS---------------ATAVPPQGSPTAS 228
           PPA       +P P S+P        PGP                  AT  P + + +A 
Sbjct: 104 PPA----KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159

Query: 229 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288
            A      PT   P   + +           P P P   P PP +    S    S  S  
Sbjct: 160 -ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 289 QP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347
           +P P   + P     LQ            P   P  A  G +  GT  A A+P       
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP--ARSGPSARGTPRAPAHPSQP---- 272

Query: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 407
                LQ+ +PP  Q  PP   A P + P  ++P               L+ PSP    A
Sbjct: 273 -KPKGLQALRPP--QVTPPRKDAAPALGPLSSSP---------------LATPSPSGTKA 314

Query: 408 NLPPPP--ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465
              PPP  A  PL +     PP A P PL         P SP+ PP L   Q LP PPA+
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLA--------PPSPSAPPSL---QTLPSPPAT 363

Query: 466 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPP---TCPSTSTPPAGPGTSAQPPCSGAAAS 522
            P             +Q P     PP   PP   T P    P +    S Q P S  A S
Sbjct: 364 PP-------------SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410

Query: 523 GGSIAGGSSCPLPTVQIKEEALD----DAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 578
             S+   +S   PT+Q     L       +   + P  P S  P+   +  P     S  
Sbjct: 411 --SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468

Query: 579 FYKHLDRGYNSCARTDLYFMPL-AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKE 637
               L    +  + + L   PL A S LA    +A   +      + +        +   
Sbjct: 469 LQTSLSPAVSPLS-SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527

Query: 638 REREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDT 696
                         A          L+ P L  P    P   + PP+ +   PP    +T
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP----ET 583

Query: 697 PA-LRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREI 755
           P+ + T    A P + SP  +  P   PL+P    LA   P      P +    L+    
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPS-PPLSP----LATPPP---QAPPXLALPPLQAPP- 634

Query: 756 REREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTI-----PPTAGPHPF 810
                                PP   PL P A P        A+ +      P   P   
Sbjct: 635 --------------------SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 811 ASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTP 870
           A F P  +P          P   P    P  LAA  +         S P +     + TP
Sbjct: 675 APFSPPASPP-------VSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPMSPSATP 722

Query: 871 HHHQHSHIHSH-LHLHQQDPLH---QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 926
                  + +  L +    P       SA P  P V PL A P L   P PP +LP   L
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPL 781

Query: 927 GQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLA 977
            +PP +      P   TP  + LP    PP S   Q     + S  +  LA
Sbjct: 782 AKPPPQ----APPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLA 825



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 118/459 (25%), Positives = 163/459 (35%), Gaps = 99/459 (21%)

Query: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 241
           A+ PA +AP  +TP P    PG+P+ P P  TP+A  V       A     +P A     
Sbjct: 14  ARTPAARAPGLLTPRP----PGSPR-PPPPVTPAALRV----LGAAGAVGRKPLA----- 59

Query: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 300
                ++A  +     P   P   P         T SAG  S    ++PP  G+G   P 
Sbjct: 60  -----ERAGGIGGATIPESAPRAGP---------TRSAGTSSRNPASRPPASGRGERAPP 105

Query: 301 -HSLQAGPLLQ--------HPGPPQPFGLPPQASQG-------QAPLGTS-PAAAYPHTS 343
             +   GP+           PGP    GL   A +        +AP  ++  A A   TS
Sbjct: 106 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 165

Query: 344 LQLPASQS---ALQSQQPPREQPLP-PAPLAMPHIKPPPTTPIPQL----------PAPQ 389
              P + S   A +S+    E  LP PAP A P  +PP   P   +          P+P 
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--RPPTEGPRKSVSSASEHSTTEPSPA 223

Query: 390 AHKHP-----------------------PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
           A + P                       P  SGPS        P  P+      L    P
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRP 282

Query: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486
           P   PP     P   PL SSP   P  + ++  P PP  +  T L    P  P    P  
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342

Query: 487 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 546
              P P  PP+  +  +PPA P + A P  +         A  S   +P +Q+       
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ----APPSLQTIPPIQVPHSL--T 396

Query: 547 AEEPESPPPPPRSPSPE-------PTVVDTPSHASQSAR 578
           +   ++PP P    S +       PT+  T S  + S R
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 140/595 (23%), Positives = 187/595 (31%), Gaps = 113/595 (18%)

Query: 412 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP-AQPPGLTQSQNLPPPPASHPPTG 470
           P  L P    S   PP   P  L+++  +  +   P A+  G      +P       PT 
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 471 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------ 524
               + + P ++ P    G     PP   ++  P + PG ++     G     G      
Sbjct: 82  SAGTSSRNPASRPP--ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139

Query: 525 -SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 583
            ++A G +   P    K  AL      ++  P P +PSP        +  S++A     L
Sbjct: 140 ETVARGKATEAP----KRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGL 189

Query: 584 DRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 643
            R   S         P  G +  K    A E +  E    AR              R   
Sbjct: 190 PRPAPSARPRP----PTEGPR--KSVSSASEHSTTEPSPAAR--------------RRPS 229

Query: 644 REREAERAAKASSSAHEGRLSDPQLSGPGHM-------RPSFEPPPTTIAAVPPYIGPD- 695
                +R A  S S+    LS P  SGP           PS   P    A  PP + P  
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 696 ---TPALRTLSEY-----------ARPHVMSPTNRNHPFYMPLNPTDPLLAYH--MPGLY 739
               PAL  LS             ARP V  P N   P    L P+ PL       P   
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348

Query: 740 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 799
           +  P+++                        P     PP   P      PM+  A  S  
Sbjct: 349 SAPPSLQTL----------------------PSPPATPPSQAPPSMTTPPMQ--APPSLQ 384

Query: 800 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHA----ERMASL 855
           TIPP   PH   S  P L       LAL+  Q    +  P   A          +  ASL
Sbjct: 385 TIPPIQVPHSLTS--PSLQA-PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441

Query: 856 TSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFP 915
           TS         +  P       + + L L    PL    +  V PL  PLT  P  A   
Sbjct: 442 TSPSRPASTPPDSPP-------LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494

Query: 916 YPPGTLPNPL--LGQPPHEHEMLRHPV--------FGTPYPRDLPGAIPPPMSAA 960
               +   PL  L  PP E +    P           TP   +LP   PPP+  A
Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)

Query: 159  PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 208
            PS P+    ++    SA   M     P  QAP  V  AP      +PP +P L      P
Sbjct: 801  PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 859

Query: 209  TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 255
            TPGP  S +      A+ P   P  S++P+   +      H+    +           P+
Sbjct: 860  TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919

Query: 256  RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 298
               +  PPP       HP+     P PPL       G P AP    PP  G G       
Sbjct: 920  GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 974

Query: 299  -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 338
                 GP S    P    PGP P   G               P QA  G+ PLG   A+ 
Sbjct: 975  IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034

Query: 339  YPH---TSLQLPASQSA 352
              H    +L L A++ A
Sbjct: 1035 VQHLLSRTLLLAAAEGA 1051



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 136/595 (22%), Positives = 191/595 (32%), Gaps = 116/595 (19%)

Query: 437 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP-TGLHQVAPQPPFAQHPFVPGGPPPITP 495
           +P+S P  + P +  G T S+N    PAS PP +G  + AP       P     P P++ 
Sbjct: 70  IPESAPR-AGPTRSAG-TSSRN----PASRPPASGRGERAP-------PAKNTSPGPVSS 116

Query: 496 PTCPSTSTPPA-----------------GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 538
           P   S +T P                  G  T A P  S  +A       G +   P+  
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSGPTPGTPSPA 175

Query: 539 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 598
           +   +     E   P P P +    PT     S +S S    +H     +  AR      
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS----EHSTTEPSPAARR----R 227

Query: 599 PLAGSKLAKKREEAIEKAKREAEQKARE------------EREREKEKEKERERERERER 646
           P AG  L +    ++  +       AR                + K K  +  R  +   
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287

Query: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYA 706
             + AA A        L+ P  SG    RP   PPP   A   P   P +P L T    A
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSGT-KARPV--PPPDNAATPLPATLPPSPPLATPLPLA 344

Query: 707 RPHVMSPTNRNHPFYMPLNP---------TDPLLAYHMPGLYNVDPTIRERELREREIRE 757
            P   +P +       P  P         T P+ A   P L  + P      L    ++ 
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA--PPSLQTIPPIQVPHSLTSPSLQA 402

Query: 758 --REIRERELRERMKPG---------FEVKPPE------LDPLHPAANPMEHFARHSALT 800
               +    L+     G         F    P         P  PA+ P +     + L+
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462

Query: 801 IPPTAGPHPFASFHPGLNPLER----------ERLALAGPQ------LRPEMSYPDRLAA 844
           +P  A P    S  P ++PL              LA   PQ      + P +     LA 
Sbjct: 463 LP--ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520

Query: 845 ERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDP 904
             +     ASLT+ PL  L      P     + + +  HL            P  P   P
Sbjct: 521 PSLQTPP-ASLTTPPLENLPSLAPPPLQTASAPLTTP-HLET----------PPCPAPCP 568

Query: 905 LTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVF-GTPYPRDLPGAIPPPMS 958
           L A P  +    PP   P+ +   PP     L  P   G P P   P A PPP +
Sbjct: 569 LQAPP--SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score =  147 bits (370), Expect = 6e-35
 Identities = 187/649 (28%), Positives = 242/649 (37%), Gaps = 151/649 (23%)

Query: 113  KKTKTQEISRPNSPSEGEG-ESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDS 171
            +K + +++      S+ +G  SS+S S ++  SSD +D + +    S     P   +   
Sbjct: 679  RKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKH 738

Query: 172  DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP--QLPTPGPTPSATAVPPQGSPTASQ 229
                 QQM QA  P  Q P    P P   PP  P  Q   P P P   ++P Q +P    
Sbjct: 739  HHHHHQQMQQAPAPVPQQPP---PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKS 795

Query: 230  APN----------QPQAP----------TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269
            +P           +PQ P          T P+ H    + P   PQ PP    PPH + H
Sbjct: 796  SPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQ-PPEHSTPPHLNQH 854

Query: 270  PPLQPLT---GSAGQPSAPSH---AQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ 323
              + P         QPS PS+   A PP   + P    +L   PLL     PQP    P 
Sbjct: 855  AVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL-----PQP----PM 905

Query: 324  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP---------REQPLPPAPLAMPHI 374
            A   Q  L      A P TS+Q+      LQ  QPP         + QP PP P   PH 
Sbjct: 906  AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP-PPPHP 964

Query: 375  K---------PPPTTPIPQLPAPQAHKHPP---HLSGPSPFSMNANLPPPPALKPLSSLS 422
                      PPP  P PQ P  Q H+ PP   HL  P  FS +   PPPP         
Sbjct: 965  SVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ-PMQFSTHIQQPPPP--------Q 1015

Query: 423  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQVAPQPPFA 481
               PP  HPPP Q     QP P  PA+P  + Q  + P    S P  TG  + AP P   
Sbjct: 1016 GQQPP--HPPPGQ-----QPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMI 1068

Query: 482  QHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKE 541
              P +              + T  + P  + QP      A+  S+      P P V +KE
Sbjct: 1069 HSPQMSQF----------QSLTHQSPPQQNVQPKKQELRAA--SVVQ----PQPLVVVKE 1112

Query: 542  EALDDA---EEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG--------YNS- 589
            E +       EP SP   P  P   P  +  P H  Q     K +D G         N+ 
Sbjct: 1113 EKIHSPIIRSEPFSPSLRPEPPK-HPESIKAPVHLPQRPEM-KPVDVGRPVIRPPEQNAP 1170

Query: 590  ------------------CARTDLYFM------------PLAGSKLAKKREEAIEKAKRE 619
                                + DL               P   S  AK   ++ E+ +R 
Sbjct: 1171 PPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRA 1230

Query: 620  AEQKAREERER-------EKEKEKERER-EREREREAERAAKASSSAHE 660
            A +K  EERE+         EKEKER R ER R RE E A + +  AHE
Sbjct: 1231 AREK--EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 50/165 (30%), Positives = 58/165 (35%), Gaps = 35/165 (21%)

Query: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 226
           N + + +  Q Q  Q  PP +QA    TP P   P  TP L     TP  T VPPQ   T
Sbjct: 198 NTTQASTPPQTQTPQPNPPPVQA----TPHPF--PAVTPDLIVQ--TPVMTVVPPQPLQT 249

Query: 227 ASQAPNQPQAPTAPVPHTHIQQAPALHPQRP-----------------PSPHPPPHPSPH 269
               P QPQ P AP P   +Q  P +    P                 P+   P H  P 
Sbjct: 250 PPPVPPQPQPPPAPAPQP-VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPS 308

Query: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314
            P +P T   GQ    S          P  P         QHP P
Sbjct: 309 LPPEPKTTKLGQRRESSR---------PVKPPKKDVPDSQQHPAP 344



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 49/155 (31%), Positives = 58/155 (37%), Gaps = 22/155 (14%)

Query: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 380
           PPQ    Q      P  A PH     PA    L  Q P     +PP PL  P   PP   
Sbjct: 205 PPQTQTPQP--NPPPVQATPHP---FPAVTPDLIVQTPVMTV-VPPQPLQTPPPVPPQPQ 258

Query: 381 PIPQLPAPQ-AHKHPPHLSG-PSP------FSMNANLPPPPALKPLSSLSTHHPPSAHPP 432
           P P  PAPQ    HPP ++  P P          A+   P  + P+     H PPS  P 
Sbjct: 259 P-PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI-----HEPPSLPPE 312

Query: 433 PLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPAS 465
           P       +   S P +PP   +  SQ  P P  S
Sbjct: 313 PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 42/143 (29%), Positives = 51/143 (35%), Gaps = 23/143 (16%)

Query: 366 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 425
           P    +P+     T P  Q P P     PP  + P PF         PA+ P   + T  
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNP---PPVQATPHPF---------PAVTPDLIVQTPV 238

Query: 426 PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 485
                P PLQ  P   P+P  P  PP        P P  SHPP  +    PQP   +   
Sbjct: 239 MTVVPPQPLQTPP---PVPPQPQPPPA-----PAPQPVQSHPP--IIAATPQPVKTKKG- 287

Query: 486 VPGGPPPITPPTCPSTSTPPAGP 508
           V       TP T      PP+ P
Sbjct: 288 VKRKADTTTPTTIDPIHEPPSLP 310



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 35/153 (22%)

Query: 189 APTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTAS-----QAPNQPQAPTAPVP 242
           A  GV+  P++    TP Q  TP P P      P   P  +     Q P     P  P+ 
Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPL- 247

Query: 243 HTHIQQAPALHPQRPPSPHPPPHPSP-------HPPL-----QPLTGSAGQPSAPSHAQP 290
                Q P   P  PP P PP  P+P       HPP+     QP+    G         P
Sbjct: 248 -----QTP---PPVPPQPQPP--PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297

Query: 291 ----PLHGQG--PPGPHSLQAGPLLQHPGPPQP 317
               P+H     PP P + + G   +   P +P
Sbjct: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP 330



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 57/243 (23%), Positives = 100/243 (41%), Gaps = 33/243 (13%)

Query: 548 EEPESPPPPPRSPS-PEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 606
           +EPE P     SP+ P PT V  P  +S S+      D   +S + TD      +  + A
Sbjct: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS-----DSSSDSDSSTDD-----SEEERA 508

Query: 607 KKREEAIEKAKREAEQKA-----REEREREKEKEKEREREREREREAERAAKASSSAHEG 661
           ++  E  E+ K   EQ A     ++ + ++KEK+K+ +++ + +R+ E      S A E 
Sbjct: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568

Query: 662 RLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720
                + +   +   S  EP P      P Y   +    + +S   +  +    N+    
Sbjct: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINK---- 624

Query: 721 YMP---LNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERE------LRERMKP 771
            +P   L     ++    P L N +P   E E+    ++   +RE E      LR++ KP
Sbjct: 625 -LPGEKLGRVVHIIQSREPSLKNSNPD--EIEIDFETLKPSTLRELERYVTSCLRKKRKP 681

Query: 772 GFE 774
             E
Sbjct: 682 QAE 684



 Score = 34.7 bits (78), Expect = 0.47
 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 16/122 (13%)

Query: 451 PGLTQSQNLP--------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPP-PI-TPPTCPS 500
           P  TQ+   P        PPP    P     V P     Q P +   PP P+ TPP  P 
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPD-LIVQTPVMTVVPPQPLQTPPPVPP 255

Query: 501 TSTPPAGPG---TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557
              PP  P      + PP   A         G      T       +D   EP S PP P
Sbjct: 256 QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT--TPTTIDPIHEPPSLPPEP 313

Query: 558 RS 559
           ++
Sbjct: 314 KT 315


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  147 bits (370), Expect = 6e-35
 Identities = 157/559 (28%), Positives = 203/559 (36%), Gaps = 64/559 (11%)

Query: 38   PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 97
            P SP G T P  E    S  N P        +  A    K A  +   +SSP K+     
Sbjct: 872  PLSPKGVTLPPKETPTPSVVNLPFP-----KEGPATPAPKQAPALSMTSSSPKKARATPA 926

Query: 98   EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 157
             K    +      S K   T   + P SP  G    S   +     ++ P          
Sbjct: 927  PKGIPASP-----SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP------KG 975

Query: 158  SPSIPSPQDNESD---SDSSAQQQMLQAQPPALQAPTGVTP-APSSAPPGTPQLPTPGPT 213
             P+ PSP+   +    +  S +       P     P  VTP +P  +P  TP        
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035

Query: 214  PSATAVPPQGSPTASQAPN-QPQAPTAPVPHTH-------IQQAPALHPQRPPSPH---- 261
            P+AT   P+GSP A+  P   P  P A +P          ++ AP      PPSP     
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095

Query: 262  -PPPHPSPHPPL----QPLTGSA-----GQPSAPSHAQP-PLHGQGPPGPHSLQAGPLLQ 310
             P P  +P PP      P  G A     G P+ P+   P P  G   P P      P   
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155

Query: 311  HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 370
             P P      PP       P  T P+   P   L  P+ + A  +  P    P P   LA
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTT--PAATPPSPKGGLA 1210

Query: 371  MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP---PALKPLSSLSTHHPP 427
             P  K  PTTP    P+P+     P   G +P +  A  P P   PA  P     T  PP
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGPATPPPKGAPT--PP 1267

Query: 428  SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV- 486
            +A PP L+    + P   +P  P  +T     PP P   P T   + AP PP A  P   
Sbjct: 1268 AATPPSLKGGLATPPHKGAP-NPAVVT-----PPSPKGGPATSPPKGAPTPPAATPPSPK 1321

Query: 487  --PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 544
              PG PPP   PT P+  TPP+  GT   P  + ++  G +       P P         
Sbjct: 1322 GSPGTPPPKGAPTPPAV-TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 545  DDAEEPESPPPPPRSPSPE 563
              A  P SP   P  PSP+
Sbjct: 1381 GPAMTPPSPKRGPAIPSPK 1399



 Score =  137 bits (346), Expect = 4e-32
 Identities = 174/651 (26%), Positives = 234/651 (35%), Gaps = 115/651 (17%)

Query: 3    KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSA 62
            K    ED G S      T  S+G+++ L         SP    SP+   +    +  P+ 
Sbjct: 768  KECPTEDSGASA-----TASSKGTLTYLAD-------SP----SPLGVSVSPQTKRPPTK 811

Query: 63   ASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKK-TKTQEIS 121
              ++  D+    +      V E +  P  S   Q  K +  T  +    S K   T    
Sbjct: 812  KGSAGPDTPIGNLSSPVSPV-EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870

Query: 122  RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181
             P SP           ++  + +  P  ++       P+ P+P+   + S +S+  +  +
Sbjct: 871  TPLSPK--------GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922

Query: 182  AQP-----PALQAPTGVTPAPSSAPP---GTPQLPTP--GPTPSATAVP----------P 221
            A P     PA  +P G    P++ PP   G P  P+P   PTP A   P          P
Sbjct: 923  ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982

Query: 222  QGSPTASQA--------PNQPQAPTAPVPHTHIQQAPALHPQRPPSPH--------PPPH 265
            +G+PT   A        P  P    AP P      +P   P   P P          PP 
Sbjct: 983  KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042

Query: 266  PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
            P   P   PL    G P+ P+   P   G GP  P SL+  P      PP P G P   S
Sbjct: 1043 PKGSPAATPL--PKGAPTTPAATLPSPKG-GPATP-SLKGAPTPPAATPPSPKGGPATPS 1098

Query: 326  QGQAP-------------LGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-----LPPA 367
               AP             L T P    P T    P S     +  PP+  P      PP+
Sbjct: 1099 PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158

Query: 368  P---LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------PALKPL 418
            P   LA P  K  PTTP    P+P+     P   G +P +  A  P P      P+ K  
Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGA 1217

Query: 419  SSLSTHHPPS-----AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP----- 468
             +     PPS     A P P          P SP   P     +  P PPA+ PP     
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277

Query: 469  --TGLHQVAPQPPFAQHPFVPGGP---PPITPPTCPSTSTPPAGPGTSAQPPCSGA---- 519
              T  H+ AP P     P   GGP   PP   PT P  +TPP+  G+   PP  GA    
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT-PPAATPPSPKGSPGTPPPKGAPTPP 1336

Query: 520  AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570
            A +  S  G  + P  T   K      + + E P PP  +PS +     TP
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSK-EGPTPPAATPSHKGGPAMTP 1386



 Score =  120 bits (302), Expect = 5e-27
 Identities = 169/640 (26%), Positives = 244/640 (38%), Gaps = 138/640 (21%)

Query: 52   IRSSGRNSPSAASTSSN-----DSKAETVKKS------AKKVKEEASSPLKSNKRQREKV 100
            ++++ +NSPS  STSS+       +A   KKS        K     +SPL  N      +
Sbjct: 563  VQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNS-SASVI 621

Query: 101  ASDTEEADRTSSKKTKTQEIS-------------RPNSPSEGEGESSDSRSVND--EG-- 143
             +D+     ++    K+  I+                +P+  +G S+ + + +   EG  
Sbjct: 622  KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681

Query: 144  SSDPKD--IDQDNRSTSPSIPSPQDN----ESDSDSSAQQQMLQAQPPALQAPTGVTPAP 197
            S  PK+  + +   +T P +P+  +N     S  ++ A    L   P   ++    +  P
Sbjct: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741

Query: 198  SSAPPGTPQL-------------------PT-------------------PGPTPSATAV 219
            +  PPGT ++                   PT                     P+P   +V
Sbjct: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSV 801

Query: 220  PPQGS--PT--ASQAPNQP----QAPTAPVPHTHI----------QQAPA-LHPQRPPSP 260
             PQ    PT   S  P+ P     +P +PV  + +          + +PA  H   PPSP
Sbjct: 802  SPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861

Query: 261  HPPPHPSPHPPLQP--LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ-- 316
               P PS   PL P  +T    +   PS    P   +GP  P   QA  L      P+  
Sbjct: 862  KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921

Query: 317  -----PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP-REQPLPPAPLA 370
                 P G+P   S   AP   +P AA P +    PA+ S   +  PP    P P    A
Sbjct: 922  RATPAPKGIPASPSPKGAP---TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978

Query: 371  MPHIKPPPTTPI---------PQLPAPQAHKHPPHLSGPS--------PFSMNANLPP-- 411
             P  K  PT P          P  P+P+    PP ++ PS        PF   A+ PP  
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038

Query: 412  -PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 470
             PP+ K  S  +T  P  A   P   +P  +  P++P+     T     PP P   P T 
Sbjct: 1039 TPPSPKG-SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 471  LHQVAPQPPFAQHPFVPGG---PPPITPPTCPSTSTPPAGPGTSAQPPCSGA----AASG 523
              + AP PP A  P   GG   PP    PT P+ +TPP+  G  A PP  GA    AA+ 
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATP 1156

Query: 524  GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 563
             S  GG + P P    K      A  P SP     +PSP+
Sbjct: 1157 PSPKGGLATPPP----KGAPTTPAATPPSPKGGLATPSPK 1192



 Score =  102 bits (255), Expect = 1e-21
 Identities = 120/470 (25%), Positives = 166/470 (35%), Gaps = 69/470 (14%)

Query: 162  PSPQDNESDSDSSAQQQMLQAQPP------ALQAPTGVTPAPSSAPPGTPQ-LPTPGP-- 212
            PSP+   +            A PP      A  +P G    P++ PP     L TP P  
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239

Query: 213  ---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP-PSPHPPPHPSP 268
               TP+AT   P+G P        P  P A  P      A   H   P P+   PP P  
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299

Query: 269  HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP------- 321
             P   P  G+   P+ P+ A PP   +G PG    +  P      PP P G P       
Sbjct: 1300 GPATSPPKGA---PTPPA-ATPP-SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 322  --------PQASQGQAPLGTSPA-----AAYPHTSLQLPASQSALQSQQPPREQPLPP-- 366
                    P + +G  P   +P+     A  P +  + PA  S       P   PL P  
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414

Query: 367  -----------APLAMPHIKPPPTTPI--PQLPAPQAHKHPPHL-SGPSPFSMNANLPP- 411
                       A  +   + PP  TP+   + PA  A K  P   S     ++ A  PP 
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474

Query: 412  ---PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468
               PPA K +++ S+     A P P+        +PSSP + P    S+  P  P +   
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA--- 1531

Query: 469  TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 528
            T L +  P     +   +P      +P   P+  TP   P T +    S   A   S   
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591

Query: 529  GSSCP--------LPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570
            G+  P        + +   KE     A  P SP   P +P+P+ T    P
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641



 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 156/656 (23%), Positives = 241/656 (36%), Gaps = 99/656 (15%)

Query: 35   KKQPASPDGRTSPINEDIRS-SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN 93
            K  P +P  + +P    +   S + +P+  +T+ +     T   S +     A++P    
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 94   ------KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDP 147
                     +   A  + + D TS           P +P   EG ++ S+     G   P
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK-----GDLTP 1435

Query: 148  KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP-----SSAPP 202
              +   +   +P+  +P+   +   S     +    PP+ + P    PAP     SS+P 
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP----PAPKQVATSSSPK 1491

Query: 203  GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA-LHPQR---PP 258
              P  P P   P+  AV P         P+  + P AP      ++ PA L P+    PP
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551

Query: 259  S---PHPPPHPS-PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314
            +   P P   P+ P P   P T S+ + S+P    P  + +G P P  L   P +  P P
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY-KGAPSPKELLIPPAVTSPSP 1610

Query: 315  PQ----PFGLPPQASQG---QAPLGTSPAAAYPHTSLQ----LPASQSALQSQQPPREQ- 362
             +    P   PP   +G    AP GT  +     +SL+     PAS +       P+   
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670

Query: 363  --PLPPAPLAMPHI---KPPPTTPI---PQLPAPQAHK----HPPHLSGPS-------PF 403
              P    P A+  +     P +TPI   P    PQ  K     PP    PS       P 
Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730

Query: 404  SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQS--QNLPP 461
            S  A  P  P  K  SS +     ++H P   L P     P S A  P LT +  + + P
Sbjct: 1731 STVAPAPLLPVQKD-SSKTAKGKDASHSPKGPLAP-----PESKASTP-LTAAAFEKVLP 1783

Query: 462  PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAA 521
             P S   +     AP PP +    +P  P P+ P   P     P+ PG   + P    A 
Sbjct: 1784 KPESASVS----AAPSPPVS----LPLAPSPV-PTLPPKQQFLPSSPGLVLESPSKPLAP 1834

Query: 522  SGGS----------IAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571
            +             I+GG   P  +V +       A  P   P   +  +       T S
Sbjct: 1835 ADEDELLPLIPPEPISGG--VPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTES 1892

Query: 572  HASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKR-EAEQKARE 626
             + +S    +  D    +  +  L       +  A+  EE + KAK+  +E+KAR+
Sbjct: 1893 DSDESVPELEEQDSTQATTQQAQL-------AAAAEIDEEPVSKAKQSRSEKKARK 1941



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 123/431 (28%), Positives = 166/431 (38%), Gaps = 69/431 (16%)

Query: 180  LQAQPPALQAPT---GVTPAPSSAPP---GTPQL-PTPGPTPSATAVPPQGSPTASQ-AP 231
            L++  PA  APT   G +   ++A P   GT  L P   P    T       PTAS+  P
Sbjct: 650  LESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCP 709

Query: 232  NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTG----SAGQPSAPSH 287
              P       P   +  AP + P+  PSP  PP  +P P  + + G    SA  P A S 
Sbjct: 710  VAPSPQNTCAPLATLVLAPEI-PKSVPSPSLPPAGTP-PGTKKVDGISHTSALAPVASSP 767

Query: 288  AQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP-------PQASQGQA----PLGTSPA 336
             + P    G     S + G L      P P G+        P   +G A    P+G   +
Sbjct: 768  KECPTEDSGASATASSK-GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826

Query: 337  AAYPHTSLQLPASQSALQ-SQQPPR--EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH 393
               P  +  LP +  + Q S+  P     P PP+P   P   P   TP+    +P+    
Sbjct: 827  PVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP--TPSAVTPL----SPKGVTL 880

Query: 394  PPHLSGPSPFSMNANLP------PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP 447
            PP  + P+P  +N   P      P P   P  S+++  P  A   P      + P P   
Sbjct: 881  PPKET-PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939

Query: 448  AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP---PTCPSTSTP 504
              PP  T     PP P   P T   + AP PP A  P   GGP   +P   PT P  +TP
Sbjct: 940  PTPPAAT-----PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT-PPAATP 993

Query: 505  PAGPGTSAQPPCSGA----AASGGSIAGG-SSCPLPTVQIKEEALDDAEEPESPPPPPRS 559
            P+  G  A P   GA    A +  S  G  ++ P P             +  S PP    
Sbjct: 994  PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP-------------KGASTPPAATP 1040

Query: 560  PSPEPTVVDTP 570
            PSP+ +   TP
Sbjct: 1041 PSPKGSPAATP 1051



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 108/422 (25%), Positives = 155/422 (36%), Gaps = 85/422 (20%)

Query: 32   SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKV------KEE 85
            S  KK PA+P    +P    +  S      A  +S  D  A T    +KK       KE 
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 86   ASSPLKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGS 144
               P  +    ++  A  T +EA  T S K    E S P + +              +G+
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSK----EASSPPAVTPS----------TYKGA 1593

Query: 145  SDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----GVTPAPS-- 198
              PK++        P++ SP   E+ +            PPA+  P+      TPAP   
Sbjct: 1594 PSPKEL-----LIPPAVTSPSPKEAPT------------PPAVTPPSPEKGPATPAPKGT 1636

Query: 199  -SAPPGTPQLPTPGPTPSATAVPPQGS--PTASQAPNQPQAPT-------APVPH-THIQ 247
             ++PP TP      PT  A+     G+  P AS+     + PT       AP P  T I 
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696

Query: 248  QAPALH-PQRPPSPHPPPHPSPHPPLQ-----PLTGSAGQPSAPSHAQPPLHGQGPPGPH 301
             AP    PQ   S    P   P P  +     PL+  A  P  P         +G    H
Sbjct: 1697 TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASH 1756

Query: 302  SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP----AAAYPHTSLQLPASQSALQSQQ 357
            S   GPL     PP+     P  +     +   P     +A P   + LP + S + +  
Sbjct: 1757 S-PKGPL----APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT-L 1810

Query: 358  PPREQPLPPAPLAMPHIKPPPTTP------IPQLPAPQAHKHPPHLSGPSPF-SMNANLP 410
            PP++Q LP +P  +      P  P      +P +P       P  +SG  PF S+  N+P
Sbjct: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIP-------PEPISGGVPFQSVLVNMP 1863

Query: 411  PP 412
             P
Sbjct: 1864 TP 1865



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 106/394 (26%), Positives = 138/394 (35%), Gaps = 76/394 (19%)

Query: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284
           P   Q   QPQA TA +P +      A   Q  P P  PP  SP P   PL       SA
Sbjct: 10  PATEQELPQPQAETAVLPMSSALSVTAALGQ--PGPTLPPPCSPAPQQCPL-------SA 60

Query: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA-PLGTSP-AAAYPHT 342
            + A P       P P ++ + PL        PF   PQ+S G A PLGT+P A  +   
Sbjct: 61  ANQASP------FPSPSTIASTPL------EVPF---PQSSSGTALPLGTAPEAPTFLPN 105

Query: 343 SLQLPASQSALQSQQPP-----REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH- 396
            +  P S +AL    P      +  P   APLA+  + P         P P     PP  
Sbjct: 106 LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFP-PNLLTSPPSV 164

Query: 397 ----------LSGP-SPFSMNANLPPPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLP 444
                     LS P +P     NL   P+    +   T  PP      P   +     + 
Sbjct: 165 AVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQ 224

Query: 445 SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST- 503
           S  A  P  T +  L         T +  V   P   Q+P       P++PP   S ST 
Sbjct: 225 SGVASLPQTTPTTTLAIASPQVKDTTISSVLISP---QNPGSLSLKGPVSPPAALSLSTQ 281

Query: 504 ---------PPAGPGTSAQPPCSGAA-------ASGGSI-----AGGSSCPLPTVQI--K 540
                      AGP T    P S  +       +S GS+      G S+   PTV+    
Sbjct: 282 SLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISV 341

Query: 541 EEALDDAEEPES----PPPPPRSPSPEPTVVDTP 570
           + +   A  P      PP P R+     TV   P
Sbjct: 342 DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFP 375



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 96/448 (21%), Positives = 138/448 (30%), Gaps = 91/448 (20%)

Query: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 241
           A     +  T V+P  SS P    +  +P     A   P + S   +     P +P  P 
Sbjct: 452 APTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPD 511

Query: 242 P----------------HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 285
           P                   +Q  PA     P SP      +   P       A   ++P
Sbjct: 512 PEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP 571

Query: 286 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 345
           S        + P  P +  A   L   G P P G P  AS   +PLG + +A+   T   
Sbjct: 572 SFQSTSSSPEIPLSPEATLAKKSL---GEPLPIGKP--ASSMTSPLGVNSSASVIKTD-- 624

Query: 346 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSM 405
                            P    PL    +  P     P   A  A   P    G S ++ 
Sbjct: 625 -------------SYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTT 671

Query: 406 NANLPPPPALKPLSSLSTHHPPSAHP------PPLQLMPQSQ------PLPSSPAQP--- 450
            A+    P L+   SL+    P  HP        L L+P +       P P +   P   
Sbjct: 672 TAS----PFLEGTVSLA----PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723

Query: 451 -------PGLTQSQNLPP---PPASHPPTGLHQVAPQPPFAQHP---------------- 484
                  P    S +LPP   PP +    G+   +   P A  P                
Sbjct: 724 LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783

Query: 485 -----FVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQI 539
                ++   P P+     P T  PP   G++      G  +S  S    S  P  ++  
Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843

Query: 540 KEEALDDAEEPESPPPPPRSPSPEPTVV 567
            + + D      SP PP    +P P+ V
Sbjct: 844 -QGSKDSPATTHSPTPPSPKGAPTPSAV 870



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 84/363 (23%), Positives = 120/363 (33%), Gaps = 63/363 (17%)

Query: 197 PSSAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 255
           P  A    P      P P A TAV P  S  +  A      PT P P +   Q   L   
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 256 RPPSPHPPPHPSPHPPLQ-PLTGSAGQPSAPSHAQPPL-----HGQGPP-GPHSLQ-AGP 307
              SP P P      PL+ P   S+   + P    P       +  GPP  P +L  A P
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121

Query: 308 LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 367
           ++       P    P A    AP     ++A+P   L  P S +  +S            
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGS--------VI 173

Query: 368 PLAMPHIKPPPTT-----PIPQLPAPQAHKHPPHLSGPSPF-------SMNANLPPPPAL 415
            L+ P     P T     P   +P P+    PP +    P+       S+ + +   P  
Sbjct: 174 TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQT 233

Query: 416 KPLSSLSTHHP------------------------PSAHPPPLQLMPQSQPLPSSPAQPP 451
            P ++L+   P                        P + P  L L  QS P+ +S  +  
Sbjct: 234 TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293

Query: 452 GLTQSQNLPPPPASHPPTGLHQVAP--QPPFAQHPFV-PGGPPPITPPTCPSTSTPPAGP 508
           G     + P    SH       +AP  Q  F     +   GP  ++ PT  + S   +  
Sbjct: 294 GPNTPPDFPISLGSH-------LAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSST 346

Query: 509 GTS 511
           G S
Sbjct: 347 GAS 349



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 109/459 (23%), Positives = 149/459 (32%), Gaps = 49/459 (10%)

Query: 147 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ-PPALQAPTGVTPAPSSAPPGTP 205
           P +  +   +T   +P PQ   +    S+   +  A   P    P   +PAP   P    
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 206 QLPTPGPTPSATA-------VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
              +P P+PS  A        P   S TA      P+APT          +PA      P
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121

Query: 259 --SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316
             +P     PS   PL  L   A      S A PP     PP     ++G ++    P  
Sbjct: 122 MIAPTLKGTPSSSAPL-ALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180

Query: 317 PFGLPPQASQGQA-------PLGT-SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368
           P    P+ +  +        P GT SP               +++QS      Q  P   
Sbjct: 181 P--SEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTT 238

Query: 369 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL--SSLSTHHP 426
           LA+   +   TT    L +PQ   +P  LS   P S  A L       P+  SS  T  P
Sbjct: 239 LAIASPQVKDTTISSVLISPQ---NPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGP 295

Query: 427 PSAHPPPLQLMPQSQPL---------------PSSPAQPPGLTQSQNLPPPPASHPPTGL 471
            +    P+ L     PL               PS+ + P   T S +     AS+P    
Sbjct: 296 NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP---- 351

Query: 472 HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 531
            Q +  PP      V        P   PS      GP T +   CS  + S       S 
Sbjct: 352 SQRSVIPPLPSRNEVVPATVAAFPVVAPSVD---KGPSTISSITCS-PSGSLNVATSFSL 407

Query: 532 CPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570
            P  ++ +K         P     P  S    P VV  P
Sbjct: 408 SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNP 446


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score =  138 bits (348), Expect = 2e-32
 Identities = 177/638 (27%), Positives = 247/638 (38%), Gaps = 97/638 (15%)

Query: 3   KPVKEEDDGLSG----KHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRN 58
           KP+ E   G+ G    + + R   +R + ++ R+   + PAS  G  +P  ++      +
Sbjct: 56  KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115

Query: 59  SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 118
           SP  AS ++        +K  +   EE  +  K+           TE   R++      +
Sbjct: 116 SPGRASGTTRPGPLG--QKGLRISAEETVARGKA-----------TEAPKRSALSAGARR 162

Query: 119 EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQ 178
           + S P   +     +  SR+   E       + +   S  P  P+    +S S S+++  
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVG-----LPRPAPSARPRPPTEGPRKSVS-SASEHS 216

Query: 179 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV--PPQGSPTASQAPNQPQA 236
             +  P A + P        SA  G  +  +   + SAT +  P +  P+A   P  P  
Sbjct: 217 TTEPSPAARRRP--------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268

Query: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
           P+ P P         L   RPP    PP     P L PL+ S     +PS A   L  Q 
Sbjct: 269 PSQPKPK-------GLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSAA---LQSQA 317

Query: 297 PPG----PHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
           PP     PHS      L  P    PP P   PP      +P  T P+ A   TSL  P  
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSP-SAPPSLQTLPSPPATPPSQAT--TSLGSPTL 374

Query: 350 QSALQSQQPPREQPL----PPAP--LAMPHIKPPPTTPI-PQL-----PAPQAHKHPPHL 397
           Q+       P   PL    P AP  LA+P ++ PP+ P  P L     P+PQA       
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434

Query: 398 SGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 452
              +PFS   + P      PPA  P+S  +T  PPS  PP L   P   P PS PA PP 
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASPP- 490

Query: 453 LTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGGPP 491
           ++ S   P   PPP + PP  L +  PQ P A                  Q PF P    
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550

Query: 492 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 551
           P++P   P    PP       Q P S  A+           P P   +    L  A  P 
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610

Query: 552 SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 589
            PPPP RSPS   +  D   H+S +    + L RGY+S
Sbjct: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 647



 Score =  117 bits (292), Expect = 7e-26
 Identities = 138/531 (25%), Positives = 195/531 (36%), Gaps = 98/531 (18%)

Query: 101 ASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 158
           A+  E A R    ++       P S  P+ G GE +         ++ P  +    R++ 
Sbjct: 68  ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK-----NTSPGPVSSPGRASG 122

Query: 159 PSIPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----P 201
            + P P   +    S  ++ A+ +  +A +  AL A        PT  TP+P+ A     
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182

Query: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261
            GT ++  P P PSA   PP   P  S +     + T P P    + +     QRP S  
Sbjct: 183 AGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241

Query: 262 PPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 320
                +P   P +    + G P AP+H   P     P G  +L+         PPQ    
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPK----PKGLQALR---------PPQVTPP 288

Query: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP-----------PAPL 369
              A+    PL +SP A         P+  +ALQSQ PP     P           P PL
Sbjct: 289 RKDAAPALGPLSSSPLAT--------PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340

Query: 370 AMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
           A P    PP+   +P  PA    +    L  P+  + ++ LP PP L PL++     PP+
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPA 399

Query: 429 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 488
              PPLQ  P     P+SP   P  T S   P   A H         P PP  Q PF P 
Sbjct: 400 LALPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPP 455

Query: 489 GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 548
             PP++P   P +  PP                         S   P +Q+         
Sbjct: 456 ASPPVSPSATPPSQAPP-------------------------SLAAPPLQVP-------- 482

Query: 549 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 599
            P  P  PP SPS  P     P  A+   +  K   +   + A   L  +P
Sbjct: 483 -PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 127/480 (26%), Positives = 166/480 (34%), Gaps = 104/480 (21%)

Query: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---------------------- 219
           A+ PA +AP  +TP     PPG+P+ P P  TP+A  V                      
Sbjct: 14  ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 220 -----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------- 267
                 P+  PT S   +     + P      ++AP   P +  SP P   P        
Sbjct: 69  TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGPVSSPGRASGTTR 125

Query: 268 PHPPLQP-LTGSAGQPSAPSHA-QPPLHGQGPPGPHSLQAGPLLQHPGPPQP-------- 317
           P P  Q  L  SA +  A   A + P       G     +GP    PG P P        
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT---PGTPSPAMARRSRA 182

Query: 318 ----FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP------PA 367
                GLP  A   +      P    P  S+   +  S  +     R +P        PA
Sbjct: 183 AGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238

Query: 368 PLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKP 417
             ++     P ++P    P+ +   + P H S P P  + A  PP          PAL P
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 418 LSS--LSTHHPPSA----HPPPLQLMPQSQ--------PLPSSPAQPPGLTQSQNLPPPP 463
           LSS  L+T  P +A     PP L   P S         PLP +P  P      Q LP PP
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358

Query: 464 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP--------AGPGTSAQPP 515
           A+ P      +      A H F+P   PP++P   P    PP        A P   A PP
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPS--PPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416

Query: 516 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-PPPRSPSPEPTVVDTPSHAS 574
            S  A          +  L             + P SPP  PP SPS  P     PS A+
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)

Query: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 208
           PS P+    ++    SA   M     P  QAP  V  AP      +PP +P L      P
Sbjct: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 590

Query: 209 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 255
           TPGP  S +      A+ P   P  S++P+   +      H+    +           P+
Sbjct: 591 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 650

Query: 256 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 298
              +  PPP       HP+     P PPL       G P AP    PP  G G       
Sbjct: 651 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 705

Query: 299 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 338
                GP S    P    PGP P   G               P QA  G+ PLG   A+ 
Sbjct: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 765

Query: 339 YPH---TSLQLPASQSA 352
             H    +L L A++ A
Sbjct: 766 VQHLLSRTLLLAAAEGA 782


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score =  136 bits (343), Expect = 9e-32
 Identities = 143/513 (27%), Positives = 195/513 (38%), Gaps = 61/513 (11%)

Query: 86   ASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDS--RSVNDEG 143
            +SS +KS         S +  ++++ S  + TQ      S S      S++  R    E 
Sbjct: 530  SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEE 589

Query: 144  SSDPKDIDQDNRSTSPSIP--SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201
            SS  + ++  NR  +  +P  SPQ       +++Q       PP    P    P P   P
Sbjct: 590  SSKAR-MESMNRPYTSLVPPLSPQPKIVTPYTASQPS-----PPLPPPPPPPPPPPPPPP 643

Query: 202  PGTPQLPTPGPTPSATAVP---PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR-- 256
            P  P LP+     + +A P      + T  Q  +Q        P   + Q+ ++ PQ   
Sbjct: 644  PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703

Query: 257  ------PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310
                  PP P PPP P+P   +  L  +   PS P  + PP   +     H  Q  P   
Sbjct: 704  PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763

Query: 311  HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL- 369
             P PP P  LPPQA     PL T PA     T      +    Q+  P    P+PPA   
Sbjct: 764  PPPPPIPAPLPPQAPP--KPLVTIPAPTSTKT-----VAPVVTQAAPPTPTPPVPPAKKQ 816

Query: 370  -AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
             A P    PP+ P P +P P     PP L     F      PPP  L P+ S+       
Sbjct: 817  PAFPASYIPPSPPTPPVPVP-----PPTLPKQQSFCAK---PPPSPLSPVPSVVKQIASQ 868

Query: 429  AHPPPLQLMPQSQPL--------PSSP----AQPPGLTQSQNLPPPPASHPPTGLHQVAP 476
              PPP     +SQPL        P SP    A+P     S  +P P    PP     V P
Sbjct: 869  FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928

Query: 477  QPPFAQHPFVPGGPPPITPPTCPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGS 530
             PP +  P  P  PPP   PT   + +P       + PG    PP     +S  S + G+
Sbjct: 929  PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS-SSGA 987

Query: 531  SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 563
              P P    K  ++D      +PP    SPS E
Sbjct: 988  EHPEP----KRPSVDSLVSKFTPPAESGSPSKE 1016



 Score =  116 bits (291), Expect = 9e-26
 Identities = 128/454 (28%), Positives = 165/454 (36%), Gaps = 92/454 (20%)

Query: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPA-LQAPTGVTPAPSSAPPGTPQLPTPGPTP 214
           S+S SIP  Q N S+   S    +   QP   +++ + V+   S A     QL       
Sbjct: 538 SSSSSIPESQSNHSNQSDSG---VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES---- 590

Query: 215 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP--- 271
           S   +     P  S  P     P    P+T  Q +P L P  PP P PPP P P PP   
Sbjct: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650

Query: 272 --LQPLTGSAGQ-----------PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP-----G 313
               P  GSA              +A  H+        PP   S    P +  P      
Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710

Query: 314 PPQPFGLPPQASQGQAPLGTSPAA------AYPHTSLQLPASQSALQSQQPPREQPLPPA 367
           PP P   PP      A L  +P A      + P   L++   Q   Q   PP   P PP 
Sbjct: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ-VAPPTPPPPPPI 769

Query: 368 PLAMPHIKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
           P  +P   PP   P+  +PAP + K   P ++  +P       P PP            P
Sbjct: 770 PAPLPPQAPP--KPLVTIPAPTSTKTVAPVVTQAAP-----PTPTPPV-----------P 811

Query: 427 PSAHPP--PLQLMPQSQPLPSSPAQPPGLTQSQNL----PPPPASHPPTGLHQVAPQPPF 480
           P+   P  P   +P S P P  P  PP L + Q+     PP P S  P+ + Q+A Q   
Sbjct: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ--- 868

Query: 481 AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540
                    PPP TPP   S    P     + Q P    A         SS P+P+    
Sbjct: 869 --------FPPPPTPPAMESQPLKPVPANVAPQSP---PAVKAKPKWQPSSIPVPS---- 913

Query: 541 EEALDDAEEPESPPPPPRS----PSPEPTVVDTP 570
                    P+ PPPPP S    P P P+ V  P
Sbjct: 914 ---------PDFPPPPPESSLVFPPPPPSPVPAP 938



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 122/437 (27%), Positives = 161/437 (36%), Gaps = 65/437 (14%)

Query: 158  SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV-TPAPSSAPPGTPQLPTPGPTPSA 216
            +PS+P              Q + Q  PP    P  +  P P  APP  P +  P PT + 
Sbjct: 734  APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP-KPLVTIPAPTSTK 792

Query: 217  TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-PALHPQRPPSPHPPPHPSPHPPLQPL 275
            T      +P  +QA   P  PT PVP    Q A PA +   PPSP  PP P P P L   
Sbjct: 793  TV-----APVVTQAA--PPTPTPPVPPAKKQPAFPASYI--PPSPPTPPVPVPPPTL--- 840

Query: 276  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 335
                  P   S    P      P P S+      Q P PP P   P   SQ   P+  + 
Sbjct: 841  ------PKQQSFCAKPPPSPLSPVP-SVVKQIASQFPPPPTP---PAMESQPLKPVPANV 890

Query: 336  AAAYPHTSLQLPASQ-SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394
            A   P      P  Q S++    P    P P + L  P   PPP +P+P  P P     P
Sbjct: 891  APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP---PPPPSPVPAPPPP-----P 942

Query: 395  PHLSGPSP------------FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 442
            P  + P+P             S      PPP  +  SS+ +    + HP P +    S  
Sbjct: 943  PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLV 1001

Query: 443  LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--------FAQHPFVPG-GPPPI 493
               +P    G    + LPPP A   P  L+      P         A+ P + G G   +
Sbjct: 1002 SKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSV 1061

Query: 494  TP-PTCPSTST-PPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550
               P+ PS S  PP  P T    PP    A      +G +S  +  V  + +        
Sbjct: 1062 VEFPSPPSDSDFPPPPPETELPLPPIEIPAV----FSGNTSPKVAVVNPQPQQWSKMSVK 1117

Query: 551  ESPPP--PPRSPSPEPT 565
            ++PPP  P R+ S   T
Sbjct: 1118 KAPPPTRPKRNDSTRLT 1134



 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 97/390 (24%), Positives = 132/390 (33%), Gaps = 97/390 (24%)

Query: 158  SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSAT 217
            +P +P P        +  +QQ   A+PP    P+ ++P PS       Q P P PTP A 
Sbjct: 830  TPPVPVPPP------TLPKQQSFCAKPP----PSPLSPVPSVVKQIASQFPPP-PTPPAM 878

Query: 218  AVPPQGSPTASQAPNQPQAPTA---------PVPHTHIQQAPA----LHPQRPPSPHPPP 264
               P     A+ AP  P A  A         PVP       P     + P  PPSP P P
Sbjct: 879  ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938

Query: 265  HPSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGPPGPH---SLQAGPLLQHPGPPQPF-- 318
             P P P   P    +G P    S    P   + PP P    S+++    +HP P +P   
Sbjct: 939  PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVD 998

Query: 319  ----GLPPQASQGQAPLGTSPAAAYPH-------TSLQLPA--SQSALQSQQPPR----- 360
                   P A  G     T P  A P        + + LP    Q  + ++ P       
Sbjct: 999  SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058

Query: 361  ----EQPLPPAPLAMPHIKPPPTTPIP----QLPAPQAHKHPPHLSGPSP-----FSMNA 407
                E P PP+    P   PPP T +P    ++PA  +    P ++  +P       M+ 
Sbjct: 1059 DSVVEFPSPPSDSDFP--PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116

Query: 408  NLPPPPALKPL--SSLSTHHPPSAHPPPLQLMPQSQPLPSSP------------------ 447
               PPP       S+  T    S  P    ++PQ    P S                   
Sbjct: 1117 KKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK 1176

Query: 448  --------------AQPPGLTQSQNLPPPP 463
                          A+P        LPPPP
Sbjct: 1177 SITRHGSLSSRMSRAEPTATMDDMALPPPP 1206



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 13/28 (46%), Positives = 15/28 (53%)

Query: 550 PESPPPPPRSPSPEPTVVDTPSHASQSA 577
           P  PPPPP  P P P     PS ++ SA
Sbjct: 630 PPPPPPPPPPPPPPPPPPPLPSQSAPSA 657



 Score = 30.4 bits (67), Expect = 8.8
 Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 550 PESPPPPPRSPSPEPTV--VDTPSHASQSARFYKH--LDRGYNSCARTDLYFMP 599
           P  PPPPP  P P P +     PS  S +  F K+  + R  N+   +   F P
Sbjct: 633 PPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP 686


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  135 bits (339), Expect = 3e-31
 Identities = 165/674 (24%), Positives = 241/674 (35%), Gaps = 134/674 (19%)

Query: 25  GSMSTLRSGRKKQPASPDGR-------TSPINEDIRSSGRNSPSAASTSSNDS----KAE 73
           G+  T++S  K+ P  P+ +       +  I E+   S     S++S+SS+ S    K +
Sbjct: 83  GASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIK 142

Query: 74  TVKKSAKKVKEEASSPLKSNKRQREK------------------------VASDTEEADR 109
           + K SA   + +    +K NK+ R K                           DT     
Sbjct: 143 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQH 202

Query: 110 ----TSSKKTKTQEIS-RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS---- 160
               TS K T  + I+ RP+ P   +     S +VN E + + K+    N+ TS      
Sbjct: 203 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 262

Query: 161 IPSPQDNESDSDSSAQQ----QMLQAQP----------PALQAPTGVTPAPSSAP----- 201
             S ++ +S   +SA+       + A+P          PAL  P   TP     P     
Sbjct: 263 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 322

Query: 202 -----------PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250
                      P TP+ P P  T SA   P + +PT ++ P  P  P  P P T  + AP
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAP 381

Query: 251 ALH--------------PQRP-------PSPHPPPHPSPHPPLQPL---------TGSAG 280
                            P++P       P+P  P  P+P  P +P          T    
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441

Query: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
            P+AP    P    +  P      A    + P P  P    P  ++        PA    
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 341 HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP------IPQLPAPQAHKHP 394
            ++   P   S   +++P    P  PAP      KP PTTP       P+ PAP   K P
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKP 559

Query: 395 PHLSG--PSPFSMNANLPPPPA-LKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSS 446
              +   P+P +     P  P  L P     L+  +   P    P  L      +P P++
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619

Query: 447 PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPP 505
           P +P   T     P  P    PT   + AP  P    P  P    P TP  T P+T   P
Sbjct: 620 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679

Query: 506 AGPGTSAQPPCSGAAASGGSIAGGSSC--PLPTVQIKEEALDDAEEPESPPPPPRSPSP- 562
           A P T  +P     A +       ++C  P PT   K  A    +EP   P  P+ P+P 
Sbjct: 680 A-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEP--APTTPKEPAPT 735

Query: 563 -----EPTVVDTPS 571
                 PT +  P+
Sbjct: 736 TPKGTAPTTLKEPA 749



 Score =  123 bits (309), Expect = 8e-28
 Identities = 154/675 (22%), Positives = 240/675 (35%), Gaps = 112/675 (16%)

Query: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107
           +N++     + + +    +S D K +T   SAK+ +    +  K      + +A  T +A
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTT--SAKETQSIEKTSAKDLAPTSKVLAKPTPKA 294

Query: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 167
           + T    TK   ++ P  P+    +   S +       +P      +  T+P  P+P   
Sbjct: 295 ETT----TKGPALTTPKEPTPTTPKEPASTT-----PKEPTPTTIKSAPTTPKEPAPTTT 345

Query: 168 ESDSDSSAQQQMLQAQPPALQAP------TGVTPAPSS--APPGTPQLPTPG-PTPSATA 218
           +S   +  +      + PA   P      T   PAP++  + P TP+ P P  P   A  
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405

Query: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGS 278
            P + +PT  + P  P  P  P P T   + PA    + P+P  P  P+P  P +P   +
Sbjct: 406 TPKEPAPTTPKEPT-PTTPKEPAPTT---KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461

Query: 279 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL-QHPGPPQPFGLP-----PQASQGQAPLG 332
             +P+  +  +P       P P + ++ P   + P P      P     P  +  + P  
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521

Query: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 389
           T+P    P T    P   +    ++P    P  PAP      KP PTTP    P  P   
Sbjct: 522 TTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTK--KPAPTTPKEPAPTTPKET 575

Query: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP----PSAHPPPLQLMPQS----- 440
           A   P  L+  +P  +    P  PA      L+   P    P+    P    P++     
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 635

Query: 441 ----------QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ----------------- 473
                     +P P++P +P   T  +  P  P    PT L +                 
Sbjct: 636 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695

Query: 474 --------------------VAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPPAGPGTSA 512
                                AP  P    P  P  P P TP  T P+T   PA P T  
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA-PTTPK 754

Query: 513 QPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP------ESPPPPPRSPSPEP 564
           +P     A   + G  +  S  P PT   KE A    +EP      +  P  P +P P  
Sbjct: 755 KPAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 813

Query: 565 TVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 624
           + V TP+   +    +K  D      +  +L   P   +     +E  +   K  A  K 
Sbjct: 814 SEVSTPTTTKEPTTIHKSPDE-----STPELSAEPTPKALENSPKEPGVPTTKTPAATKP 868

Query: 625 REEREREKEKEKERE 639
            E     K+K  ER+
Sbjct: 869 -EMTTTAKDKTTERD 882



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 44/245 (17%), Positives = 86/245 (35%), Gaps = 15/245 (6%)

Query: 38   PASPDGRTS-----PINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92
            P +  G TS     P     + +   +P   + ++    A T  ++      E S+P  +
Sbjct: 763  PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 822

Query: 93   NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSSDPKD-- 149
             +      + D    + ++    K  E    NSP E G   +    +   E ++  KD  
Sbjct: 823  KEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKT 878

Query: 150  IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 209
             ++D R+T P   +     +   ++  ++  +++  A       T    + P     L T
Sbjct: 879  TERDLRTT-PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 937

Query: 210  PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269
                P  T    + + T ++  N+P+    P       +A    PQ+P      P  +  
Sbjct: 938  TTLAPKVTTT--KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 995

Query: 270  PPLQP 274
            P   P
Sbjct: 996  PKTMP 1000



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 68/367 (18%), Positives = 119/367 (32%), Gaps = 57/367 (15%)

Query: 36   KQPA----SPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP-- 89
            K+PA    +P     P +         +P   + ++    A T  K       + ++P  
Sbjct: 685  KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 744

Query: 90   LKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148
            LK       K  +  E A  T+   T T  +   P +P E     +   +  +   + PK
Sbjct: 745  LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE-----TAPTTPKEPAPTTPK 799

Query: 149  DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP---TGVTPAPSSAPPGTP 205
                    T+P  P P  +E  + ++ ++     + P    P      TP      P  P
Sbjct: 800  K----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855

Query: 206  QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH 265
             +PT   TP+AT   P+ + TA     +    T P   T    AP +  +   +      
Sbjct: 856  GVPTT-KTPAAT--KPEMTTTAKDKTTERDLRTTPETTT---AAPKMTKETATTTEKTTE 909

Query: 266  PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
                     +T +  Q + P                              +   L P+ +
Sbjct: 910  SKITATTTQVTSTTTQDTTPFKIT------------------------TLKTTTLAPKVT 945

Query: 326  QGQAPLGTSPAAAYPHTSL----QLPASQSALQSQQPPREQPLPPA----PLAMPHIKPP 377
              +  + T+     P  +     +   S++     Q P + P  P     P  MP ++ P
Sbjct: 946  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1005

Query: 378  PTTPIPQ 384
             TTP P+
Sbjct: 1006 KTTPTPR 1012


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  135 bits (339), Expect = 3e-31
 Identities = 165/674 (24%), Positives = 241/674 (35%), Gaps = 134/674 (19%)

Query: 25  GSMSTLRSGRKKQPASPDGR-------TSPINEDIRSSGRNSPSAASTSSNDS----KAE 73
           G+  T++S  K+ P  P+ +       +  I E+   S     S++S+SS+ S    K +
Sbjct: 124 GASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIK 183

Query: 74  TVKKSAKKVKEEASSPLKSNKRQREK------------------------VASDTEEADR 109
           + K SA   + +    +K NK+ R K                           DT     
Sbjct: 184 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQH 243

Query: 110 ----TSSKKTKTQEIS-RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS---- 160
               TS K T  + I+ RP+ P   +     S +VN E + + K+    N+ TS      
Sbjct: 244 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 303

Query: 161 IPSPQDNESDSDSSAQQ----QMLQAQP----------PALQAPTGVTPAPSSAP----- 201
             S ++ +S   +SA+       + A+P          PAL  P   TP     P     
Sbjct: 304 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 363

Query: 202 -----------PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250
                      P TP+ P P  T SA   P + +PT ++ P  P  P  P P T  + AP
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAP 422

Query: 251 ALH--------------PQRP-------PSPHPPPHPSPHPPLQPL---------TGSAG 280
                            P++P       P+P  P  P+P  P +P          T    
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482

Query: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
            P+AP    P    +  P      A    + P P  P    P  ++        PA    
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 341 HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP------IPQLPAPQAHKHP 394
            ++   P   S   +++P    P  PAP      KP PTTP       P+ PAP   K P
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKP 600

Query: 395 PHLSG--PSPFSMNANLPPPPA-LKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSS 446
              +   P+P +     P  P  L P     L+  +   P    P  L      +P P++
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660

Query: 447 PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPP 505
           P +P   T     P  P    PT   + AP  P    P  P    P TP  T P+T   P
Sbjct: 661 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720

Query: 506 AGPGTSAQPPCSGAAASGGSIAGGSSC--PLPTVQIKEEALDDAEEPESPPPPPRSPSP- 562
           A P T  +P     A +       ++C  P PT   K  A    +EP   P  P+ P+P 
Sbjct: 721 A-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEP--APTTPKEPAPT 776

Query: 563 -----EPTVVDTPS 571
                 PT +  P+
Sbjct: 777 TPKGTAPTTLKEPA 790



 Score =  123 bits (309), Expect = 8e-28
 Identities = 154/675 (22%), Positives = 240/675 (35%), Gaps = 112/675 (16%)

Query: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107
           +N++     + + +    +S D K +T   SAK+ +    +  K      + +A  T +A
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTT--SAKETQSIEKTSAKDLAPTSKVLAKPTPKA 335

Query: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 167
           + T    TK   ++ P  P+    +   S +       +P      +  T+P  P+P   
Sbjct: 336 ETT----TKGPALTTPKEPTPTTPKEPASTT-----PKEPTPTTIKSAPTTPKEPAPTTT 386

Query: 168 ESDSDSSAQQQMLQAQPPALQAP------TGVTPAPSS--APPGTPQLPTPG-PTPSATA 218
           +S   +  +      + PA   P      T   PAP++  + P TP+ P P  P   A  
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446

Query: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGS 278
            P + +PT  + P  P  P  P P T   + PA    + P+P  P  P+P  P +P   +
Sbjct: 447 TPKEPAPTTPKEPT-PTTPKEPAPTT---KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502

Query: 279 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL-QHPGPPQPFGLP-----PQASQGQAPLG 332
             +P+  +  +P       P P + ++ P   + P P      P     P  +  + P  
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562

Query: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 389
           T+P    P T    P   +    ++P    P  PAP      KP PTTP    P  P   
Sbjct: 563 TTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTK--KPAPTTPKEPAPTTPKET 616

Query: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP----PSAHPPPLQLMPQS----- 440
           A   P  L+  +P  +    P  PA      L+   P    P+    P    P++     
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 676

Query: 441 ----------QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ----------------- 473
                     +P P++P +P   T  +  P  P    PT L +                 
Sbjct: 677 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736

Query: 474 --------------------VAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPPAGPGTSA 512
                                AP  P    P  P  P P TP  T P+T   PA P T  
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA-PTTPK 795

Query: 513 QPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP------ESPPPPPRSPSPEP 564
           +P     A   + G  +  S  P PT   KE A    +EP      +  P  P +P P  
Sbjct: 796 KPAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 854

Query: 565 TVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 624
           + V TP+   +    +K  D      +  +L   P   +     +E  +   K  A  K 
Sbjct: 855 SEVSTPTTTKEPTTIHKSPDE-----STPELSAEPTPKALENSPKEPGVPTTKTPAATKP 909

Query: 625 REEREREKEKEKERE 639
            E     K+K  ER+
Sbjct: 910 -EMTTTAKDKTTERD 923



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 44/245 (17%), Positives = 86/245 (35%), Gaps = 15/245 (6%)

Query: 38   PASPDGRTS-----PINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92
            P +  G TS     P     + +   +P   + ++    A T  ++      E S+P  +
Sbjct: 804  PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 863

Query: 93   NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSSDPKD-- 149
             +      + D    + ++    K  E    NSP E G   +    +   E ++  KD  
Sbjct: 864  KEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKT 919

Query: 150  IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 209
             ++D R+T P   +     +   ++  ++  +++  A       T    + P     L T
Sbjct: 920  TERDLRTT-PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 978

Query: 210  PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269
                P  T    + + T ++  N+P+    P       +A    PQ+P      P  +  
Sbjct: 979  TTLAPKVTTT--KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 1036

Query: 270  PPLQP 274
            P   P
Sbjct: 1037 PKTMP 1041



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 68/367 (18%), Positives = 119/367 (32%), Gaps = 57/367 (15%)

Query: 36   KQPA----SPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP-- 89
            K+PA    +P     P +         +P   + ++    A T  K       + ++P  
Sbjct: 726  KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 785

Query: 90   LKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148
            LK       K  +  E A  T+   T T  +   P +P E     +   +  +   + PK
Sbjct: 786  LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE-----TAPTTPKEPAPTTPK 840

Query: 149  DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP---TGVTPAPSSAPPGTP 205
                    T+P  P P  +E  + ++ ++     + P    P      TP      P  P
Sbjct: 841  K----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896

Query: 206  QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH 265
             +PT   TP+AT   P+ + TA     +    T P   T    AP +  +   +      
Sbjct: 897  GVPTT-KTPAAT--KPEMTTTAKDKTTERDLRTTPETTT---AAPKMTKETATTTEKTTE 950

Query: 266  PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
                     +T +  Q + P                              +   L P+ +
Sbjct: 951  SKITATTTQVTSTTTQDTTPFKIT------------------------TLKTTTLAPKVT 986

Query: 326  QGQAPLGTSPAAAYPHTSL----QLPASQSALQSQQPPREQPLPPA----PLAMPHIKPP 377
              +  + T+     P  +     +   S++     Q P + P  P     P  MP ++ P
Sbjct: 987  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1046

Query: 378  PTTPIPQ 384
             TTP P+
Sbjct: 1047 KTTPTPR 1053


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  132 bits (333), Expect = 1e-30
 Identities = 152/480 (31%), Positives = 179/480 (37%), Gaps = 81/480 (16%)

Query: 117  TQEISRPNSP-----SEGEGE--SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNES 169
            TQ IS+P  P     S G+G+  S    S++ E  +  +         S +IPSP     
Sbjct: 804  TQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC 863

Query: 170  DSDSSAQQQ--MLQAQPPALQAPTGVTPAPSSAPPGTPQL-------PTPGPTPSATAVP 220
               SS+     M+   PP L   T V   PS+A P  P L       P P P P A   P
Sbjct: 864  TESSSSMPGLGMVPPPPPPLPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922

Query: 221  PQGSPTASQAPNQPQ-----APTAPVPHTHIQQAPALH----PQRPPSPH---PPPHPSP 268
            P   P A   P  P       P  P+P   I   P L     P  PP P    PPP P P
Sbjct: 923  PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982

Query: 269  H---PPLQPLTGSAGQPSAPSHA-----QPPLHGQGPPGPHSLQAGPLLQHPGPPQP-FG 319
                PP  PL G+   P  P         PPL G G P P  L    +   P PP P  G
Sbjct: 983  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAG 1040

Query: 320  LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP----PAPLAMPHIK 375
            +PP      A  G  P    P   +  P          PP   PLP    P P  +P   
Sbjct: 1041 IPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAG 1095

Query: 376  PPPTTPIPQLPAPQAHKHPPHLSG----PSPFSMNANLPPPPALKPLSSLSTHHPPSAHP 431
             PP  P+P +  P     PP L G    P P    A +PPPP   PL       PP   P
Sbjct: 1096 IPPPPPLPGVGIPP----PPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPP---P 1145

Query: 432  PPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP-----ASHPPTGLHQVAPQPPFAQHPFV 486
             P   +P   PLP +   PP       +PPPP        PP  L  V   PP    P +
Sbjct: 1146 LPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP----PPL 1201

Query: 487  PG-GPPPITPPTCPSTSTPPA------GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQI 539
            PG G PP  PP  P    PPA       PGT   PP     +    +    S  LPT Q+
Sbjct: 1202 PGAGIPP--PPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 88/282 (31%), Positives = 103/282 (36%), Gaps = 44/282 (15%)

Query: 184  PPALQAPTGVTPAP----SSAPPGTPQ----LPTPGPTPSATAVPPQGSPTASQAPNQPQ 235
            PP      G+ P P    +  PP  P     +P P P P A   PP   P A   P  P 
Sbjct: 999  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058

Query: 236  A-----PTAPVPHTHIQQAPALH----PQRPPSPH---PPPHPSPH---PPLQPLTGSAG 280
                  P  P+P   I   P L     P  PP P    PPP P P    PP  PL G+  
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118

Query: 281  QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQASQGQAPLGTSPAAAY 339
             P       PPL G G P P  L    +   P PP P  G+PP      A  G  P    
Sbjct: 1119 PPP------PPLPGAGIPPPPPLPGAGI--PPPPPLPRVGIPPPPPLPGA--GIPPPPPL 1168

Query: 340  PHTSLQLPASQSALQSQQPPREQPLP----PAPLAMPHIKPPPTTPIPQL---PAPQAHK 392
            P   +  P     +    PP   PLP    P P  +P    PP  P+P +   PAP    
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPP---PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPL 1225

Query: 393  HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL 434
             PP    P P  +  + PP       S+L T       PPPL
Sbjct: 1226 PPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267



 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 103/350 (29%), Positives = 122/350 (34%), Gaps = 85/350 (24%)

Query: 272  LQPLTGSAGQPSAPSHAQPPLHGQGP-------------PGPHSLQAG---PLLQHPGPP 315
            L P+ G  G+P  P  A+      GP             P   S+Q     P      PP
Sbjct: 757  LPPVDGLPGRPPCPPGAE-----SGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811

Query: 316  QPFGLPPQASQGQAPLGTSPAAAYPH-------TSLQLPASQSALQSQQPPREQPLP--P 366
             P  L   A QGQ      P +  PH       TS +   S +   S   P   PLP   
Sbjct: 812  PPPSLLWSAGQGQ------PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865

Query: 367  APLAMPHIK--PPPTTPIPQLPAPQ----AHKHPPHLSG------PSPFSMNANLPPPP- 413
            +  +MP +   PPP  P+P +  P     A   PP L G      P P    A +PPPP 
Sbjct: 866  SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925

Query: 414  -------ALKPLSSLSTHHPP----SAHPPPLQL----MPQSQPLPSSPAQPPGLTQSQN 458
                    L PL       PP    +A PPP  L    +P   PLP +   PP       
Sbjct: 926  LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG 985

Query: 459  LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP----AGPGTSAQP 514
            +PPPP   P  G+    P PP    P    G PP  PP  P    PP     G G    P
Sbjct: 986  IPPPPPL-PGAGI----PPPP----PLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPP 1034

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 564
            P  GA         G+  P P        L  A  P  PP P     P P
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPP------PPLPGAGIPPPPPLPGAGIPPPP 1078



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 62/201 (30%), Positives = 72/201 (35%), Gaps = 27/201 (13%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA-----PT 238
            PP      G+ P P     G   +P P P P A   PP   P A   P  P       P 
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154

Query: 239  APVPHTHIQQAPALH----PQRPPSPH---PPPHPSPH---PPLQPLTGSAGQPSAPSHA 288
             P+P   I   P L     P  PP P    PPP P P    PP  PL G+   P      
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP------ 1208

Query: 289  QPPLHGQG-PPGPHSLQAGPLLQHPGPP-QPFGLPPQASQ-GQAPLGTSPAAAYPHTSLQ 345
             PPL G G PP P      P    P PP  P   PP   Q G + L T     +    L 
Sbjct: 1209 PPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268

Query: 346  LPASQSALQSQQPPREQPLPP 366
                   +   +  R+QP+ P
Sbjct: 1269 SGLFGLGMNQDKGSRKQPIEP 1289



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 91/381 (23%), Positives = 125/381 (32%), Gaps = 65/381 (17%)

Query: 56  GRNSPSAASTSSNDSKAET-----VKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT 110
           G    S    S +DS+A       ++K+  K K    S     +   +  A  T E D  
Sbjct: 56  GGGGESGKKKSKSDSRASVFSNLRIRKNLSKGKGAGGS----REDVLDSQALQTGELDSA 111

Query: 111 SSKKTKTQEIS-RPNSPSEGEGESSDSRSVNDEGSSDP-----------KDID-----QD 153
            S  TKT ++S   +     + E +D   V   G   P           +D++     QD
Sbjct: 112 HSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQD 171

Query: 154 NRSTSP----------SIPSPQDNESDSDSSA-----QQQMLQAQPPALQAPTGVTPAPS 198
            + TS           S    +D  SD   +      QQQ LQ Q    Q    +  A  
Sbjct: 172 GQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEE 231

Query: 199 SAPPGTPQLPTPGPTPSATAV---PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 255
            A P T   P PG           P  G+  A  +P+  QA +A         A    PQ
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291

Query: 256 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 315
           +PPSP   P  S  P L      A QP+A              GP    AG  ++  G  
Sbjct: 292 QPPSPGGLP-VSEAPSL-----PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345

Query: 316 QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 375
              G   + +   AP G+      P      P        ++P  E   P AP A     
Sbjct: 346 DEEG--EEDAFEDAPRGSPGEEWAPEVGEDAPQR----LGEEPEEEAQGPDAPAA----- 394

Query: 376 PPPTTPIPQLPAPQAHKHPPH 396
                 +P  PAP      P+
Sbjct: 395 ----ASLPGSPAPSQRCFKPY 411



 Score = 30.4 bits (67), Expect = 8.8
 Identities = 38/157 (24%), Positives = 53/157 (33%), Gaps = 30/157 (19%)

Query: 444 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST 503
           P SP     L+   +LP             +A +P   Q P  PGG P    P+ P+   
Sbjct: 264 PGSPDTEQALSALSDLP-----------ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQP 312

Query: 504 -------------PPAGPG-TSAQPPCSGAAASG--GSIAGGSSCP--LPTVQIKEEALD 545
                        P AGPG  +A  P  GA  +   G        P   P  +   E  +
Sbjct: 313 AAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGE 372

Query: 546 DAEEPESPPPPPRSPSPE-PTVVDTPSHASQSARFYK 581
           DA +     P   +  P+ P     P   + S R +K
Sbjct: 373 DAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFK 409


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score =  132 bits (331), Expect = 2e-30
 Identities = 165/562 (29%), Positives = 219/562 (38%), Gaps = 94/562 (16%)

Query: 101 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 160
           A+  E A R    +T     SRP  P+ G GE +         ++ P  +    R++  +
Sbjct: 68  ATIPESAPRAGPTRT-----SRP--PASGRGERAPPAK-----NTSPGPVSSPGRASGTT 115

Query: 161 IPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----PPG 203
            P P   +    S  ++ A+ +  +A +  AL A        PT  TP+P+ A      G
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175

Query: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263
           T ++  P P PSA   PP   P  S +     + T P P    + +     QRP S    
Sbjct: 176 T-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234

Query: 264 PHPSP-HPPLQPLTGSAGQPSAPSHAQPP----LHGQGPPG---PHSLQA---GPLLQHP 312
              +P   P +    + G P AP+H   P    L    PP    P    A   GPL   P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294

Query: 313 -------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL- 364
                   PP P   PP      +P  T P+ A   TSL  P  Q+       P   PL 
Sbjct: 295 LATPSPSAPPSP-SAPPSLQTLPSPPATPPSQAT--TSLGSPTLQATHSFLPSPPLSPLA 351

Query: 365 ---PPAP--LAMPHIKPPPTTPI-PQL-----PAPQAHKHPPHLSGPSPFSMNANLP--- 410
              P AP  LA+P ++ PP+ P  P L     P+PQA          +PFS   + P   
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411

Query: 411 --PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP---PPPAS 465
              PPA  P+S  +T  PPS  PP L   P   P PS PA PP ++ S   P   PPP +
Sbjct: 412 PFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASPP-MSPSATPPPQAPPPLA 467

Query: 466 HPPTGLHQVAPQPPFA------------------QHPFVPGGPPPITPPTCPSTSTPPAG 507
            PP  L +  PQ P A                  Q PF P    P++P   P    PP  
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 527

Query: 508 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 567
                Q P S  A+           P P   +    L  A  P  PPPP RSPS   +  
Sbjct: 528 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587

Query: 568 DTPSHASQSARFYKHLDRGYNS 589
           D   H+S +    + L RGY+S
Sbjct: 588 DLAGHSSSATSTPEEL-RGYDS 608



 Score =  127 bits (318), Expect = 7e-29
 Identities = 176/658 (26%), Positives = 229/658 (34%), Gaps = 142/658 (21%)

Query: 3   KPVKEEDDGLSGKHSMRTRRSRGSMSTLR---SGR-KKQPASPDGRTSPINEDIRSSGRN 58
           KP+ E   G+ G     +    G   T R   SGR ++ P + +    P++   R+SG  
Sbjct: 56  KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115

Query: 59  SP----------SAASTSSNDSKAETVKKSAKKV--KEEASSPLKSNKRQREKVASDTEE 106
            P          SA  T +     E  K+SA     + + S P            +    
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPAMARRSR 172

Query: 107 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---------------GSSDPKDID 151
           A  T     +    +RP  P+EG  +S  S S +                 G   P    
Sbjct: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232

Query: 152 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQA--PTGVTPAPSSAPPGT-PQLP 208
             + +T  S P+     +     A     Q +P  LQA  P  VTP    A P   P   
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292

Query: 209 TPGPTPSATAVP-PQGSPTASQAPNQPQAP----TAPVPHTHIQQAPALHPQRPPSP--H 261
           +P  TPS +A P P   P+    P+ P  P    T  +    +Q   +  P  P SP   
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352

Query: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP-----HSLQAGPLLQHPGPPQ 316
           PPP   P   L PL      P++P  +  PL    P  P     H LQA P    P PP 
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLS--PLATPSPQAPNALAVHLLQA-PFSPPPSPPV 409

Query: 317 PFGLPPQASQGQAPLGTSPAAAYPHTS---LQLPASQSALQSQQPPREQP-LPPAPLAMP 372
                P AS   +P  T P+ A P  +   LQ+P S  A     P    P   P PLA P
Sbjct: 410 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 469

Query: 373 HI---KPPPTTPIPQLPAP--QAHKHPP-HLSGPSPFSMNANLP------PPPALKP-LS 419
            +   KPPP  P P L  P  QA   PP    G +PFS +A+LP      PPP   P L+
Sbjct: 470 PLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528

Query: 420 SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG----LTQSQNLPPPPASHPPTGLH--- 472
           +     PPS    P    P+  P P       G    L  +   PPPP+  P + L    
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588

Query: 473 -------------------------QVAPQPPFAQ----HPFV--------------PGG 489
                                      A  PP A+    HP                PG 
Sbjct: 589 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 648

Query: 490 PPPITPPT--------C-------PSTSTPPAG-------PGTSAQPPCSGAAASGGS 525
           P P  P T        C       P ++TP  G       PGTS     +GA A   S
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 706



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 127/444 (28%), Positives = 163/444 (36%), Gaps = 71/444 (15%)

Query: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-----SPTASQAPN---- 232
           A+ PA +AP  +TP     PPG+P+ P P  TP+A  V          P A +A      
Sbjct: 14  ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 233 --QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT---GSAGQPSAPSH 287
                AP A    T    A     + PP+ +  P P   P     T   G  GQ      
Sbjct: 69  TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128

Query: 288 AQPPL-HGQGPPGP--HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS---------- 334
           A+  +  G+    P   +L AG      GP      P  A + +A  GT           
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGLPRPAPSA 187

Query: 335 ---PAAAYPHTSLQLPASQSALQSQQPPREQPLP------PAPLAMPHIKPPPTTPIPQL 385
              P    P  S+   +  S  +     R +P        PA  ++     P ++P    
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247

Query: 386 PAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKPLSSLSTHHPPSAHPPPLQ 435
           P+ +   + P H S P P  + A  PP          PAL PLSS     P  + PP   
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307

Query: 436 LMPQSQPLPSSPAQPPG-LTQSQNLPPPPASH---PPTGLHQVAPQPPFAQHPFVPGGPP 491
             P  Q LPS PA PP   T S   P   A+H   P   L  +A  PP  Q P     PP
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPP 365

Query: 492 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 551
              PP+ P  ++PP  P  +  P    A A     A  S  P P VQ           P 
Sbjct: 366 LQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ----------APF 413

Query: 552 SPP-PPPRSPSPEPTVVDTPSHAS 574
           SPP  PP SPS  P     PS A+
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAA 437



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)

Query: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 208
           PS P+    ++    SA   M     P  QAP  V  AP      +PP +P L      P
Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 551

Query: 209 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 255
           TPGP  S +      A+ P   P  S++P+   +      H+    +           P+
Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611

Query: 256 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 298
              +  PPP       HP+     P PPL       G P AP    PP  G G       
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 666

Query: 299 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 338
                GP S    P    PGP P   G               P QA  G+ PLG   A+ 
Sbjct: 667 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 726

Query: 339 YPH---TSLQLPASQSA 352
             H    +L L A++ A
Sbjct: 727 VQHLLSRTLLLAAAEGA 743



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 144/644 (22%), Positives = 201/644 (31%), Gaps = 86/644 (13%)

Query: 364 LPPAPLAMPHIKPPPTTP--IPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 414
           L P P   P   PPP TP  +  L A  A    P       + G + P S     P   +
Sbjct: 25  LTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83

Query: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474
             P S      PP+ +  P    P S P  +S    PG    + L          G    
Sbjct: 84  RPPASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140

Query: 475 APQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAG---------PGTSAQPPCSGAAASG 523
           AP+     A       GP P TP    +  +  AG         P    +PP  G   S 
Sbjct: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200

Query: 524 GSIAGGSSC-PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 582
            S +  S+  P P  + +  A    + P S     RS S   T + +P+ +  SAR    
Sbjct: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPAS-----RSLSSSATPLSSPARSGPSARGTPR 255

Query: 583 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK-AKREAEQKAREEREREKEKEKERERE 641
                +      L    L   ++   R++A        +   A                +
Sbjct: 256 APAHPSQPKPKGL--QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313

Query: 642 REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRT 701
                 A   ++A++S     L  P L       PS   PP +  A PP   P   AL  
Sbjct: 314 TLPSPPATPPSQATTS-----LGSPTLQATHSFLPS---PPLSPLATPPPQAPPALALPP 365

Query: 702 LSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM-PGLYNVDPTIRERELREREIREREI 760
           L     P    P +   P   P       LA H+    ++  P+   +            
Sbjct: 366 LQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422

Query: 761 RERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPL 820
                  +  P     P ++ P  PA+ PM      S    PP   P P A+      PL
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPM------SPSATPPPQAPPPLAA-----PPL 471

Query: 821 ERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHS 880
           +   LA   PQ  P ++ P   A     A         P A L M  +     Q   + +
Sbjct: 472 Q---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528

Query: 881 HLHLH-----QQDPLHQGSAGPVHPLVDPLTAGPHLARF-----PYPPGTLPNPLLGQPP 930
              L         P  Q    P  P  D   +GP L        P PP   P+  L  P 
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP- 587

Query: 931 HEHEMLRHPVFGTPYPRDLPG----------AIPPP---MSAAH 961
              ++  H    T  P +L G          A PPP   ++A H
Sbjct: 588 ---DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  130 bits (327), Expect = 6e-30
 Identities = 138/598 (23%), Positives = 214/598 (35%), Gaps = 70/598 (11%)

Query: 29  TLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASS 88
           T +    K P   +  +   N D + +   +P  ++T  N         +AK +    S 
Sbjct: 74  TKKKPTPKPPVVDEAGSGLDNGDFKVT---TPDTSTTQHNKVSTSPKITTAKPINPRPSL 130

Query: 89  PLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148
           P  S+  +   +  + E    T    T  ++ S     ++G+ +++ ++       +  K
Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTS-----TDGKEKTTSAKETQSIEKTSAK 185

Query: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPGTPQ 206
           D+   ++  +   P  +        +  ++     P  PA   P   TP    + P TP+
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245

Query: 207 LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH------------- 253
            P P  T SA   P + +PT ++ P  P  P  P P T  + AP                
Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304

Query: 254 -PQRP-------PSPHPPPHPSPHPPLQPL---------TGSAGQPSAPSHAQPPLHGQG 296
            P++P       P+P  P  P+P  P +P          T     P+AP    P    + 
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 364

Query: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
            P      A    + P P  P    P  ++        PA     ++   P   S   ++
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424

Query: 357 QPPREQPLPPAPLAMPHIKPPPTTP------IPQLPAPQAHKHPPHLSG--PSPFSMNAN 408
           +P    P  PAP      KP PTTP       P+ PAP   K P   +   P+P +    
Sbjct: 425 EPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482

Query: 409 LPPPPA-LKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462
            P  P  L P     L+  +   P    P  L      +P P++P +P   T     P  
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542

Query: 463 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPPAGPGTSAQPPCSGAAA 521
           P    PT   + AP  P    P  P    P TP  T P+T   PA P T  +P     A 
Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA-PTTPKKPAPKELAP 601

Query: 522 SGGSIAGGSSC--PLPTVQIKEEALDDAEEPESPPPPPRSPSP------EPTVVDTPS 571
           +       ++C  P PT   K  A    +EP   P  P+ P+P       PT +  P+
Sbjct: 602 TTTKEPTSTTCDKPAPTTP-KGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPA 656



 Score =  123 bits (309), Expect = 8e-28
 Identities = 154/675 (22%), Positives = 240/675 (35%), Gaps = 112/675 (16%)

Query: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107
           +N++     + + +    +S D K +T   SAK+ +    +  K      + +A  T +A
Sbjct: 144 VNKETTVETKETTTTNKQTSTDGKEKTT--SAKETQSIEKTSAKDLAPTSKVLAKPTPKA 201

Query: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 167
           + T    TK   ++ P  P+    +   S +       +P      +  T+P  P+P   
Sbjct: 202 ETT----TKGPALTTPKEPTPTTPKEPASTT-----PKEPTPTTIKSAPTTPKEPAPTTT 252

Query: 168 ESDSDSSAQQQMLQAQPPALQAP------TGVTPAPSS--APPGTPQLPTPG-PTPSATA 218
           +S   +  +      + PA   P      T   PAP++  + P TP+ P P  P   A  
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312

Query: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGS 278
            P + +PT  + P  P  P  P P T   + PA    + P+P  P  P+P  P +P   +
Sbjct: 313 TPKEPAPTTPKEPT-PTTPKEPAPTT---KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368

Query: 279 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL-QHPGPPQPFGLP-----PQASQGQAPLG 332
             +P+  +  +P       P P + ++ P   + P P      P     P  +  + P  
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428

Query: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 389
           T+P    P T    P   +    ++P    P  PAP      KP PTTP    P  P   
Sbjct: 429 TTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTK--KPAPTTPKEPAPTTPKET 482

Query: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP----PSAHPPPLQLMPQS----- 440
           A   P  L+  +P  +    P  PA      L+   P    P+    P    P++     
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542

Query: 441 ----------QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ----------------- 473
                     +P P++P +P   T  +  P  P    PT L +                 
Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602

Query: 474 --------------------VAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPPAGPGTSA 512
                                AP  P    P  P  P P TP  T P+T   PA P T  
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA-PTTPK 661

Query: 513 QPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP------ESPPPPPRSPSPEP 564
           +P     A   + G  +  S  P PT   KE A    +EP      +  P  P +P P  
Sbjct: 662 KPAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 720

Query: 565 TVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 624
           + V TP+   +    +K  D      +  +L   P   +     +E  +   K  A  K 
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDE-----STPELSAEPTPKALENSPKEPGVPTTKTPAATKP 775

Query: 625 REEREREKEKEKERE 639
            E     K+K  ER+
Sbjct: 776 -EMTTTAKDKTTERD 789



 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 120/512 (23%), Positives = 180/512 (35%), Gaps = 43/512 (8%)

Query: 95  RQREKVASDTEE--ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ 152
           ++ +K   D E   A+   +KK +T++   P  P   E  S          + D      
Sbjct: 50  KKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQH 109

Query: 153 DNRSTSPSI-------PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 205
           +  STSP I       P P     +SD+S +  +   +   ++     T    ++  G  
Sbjct: 110 NKVSTSPKITTAKPINPRP-SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 168

Query: 206 QLPTPGPTPSATAVPPQG-SPTAS-QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263
           +  +   T S      +  +PT+   A   P+A T         + PAL   + P+P  P
Sbjct: 169 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT-------TKGPALTTPKEPTPTTP 221

Query: 264 PHPSPHPPLQPL-TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322
             P+   P +P  T     P+ P    P      P  P    A    + P P  P    P
Sbjct: 222 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE-PAPTTTKEPAPTTPKEPAP 280

Query: 323 QASQGQAPLGTSPAAAYPH----TSLQLPASQSALQSQQPPREQPLPPAPL--AMPHIKP 376
             ++  AP  T  A   P     T+ + PA  +  +      ++P P  P   A    +P
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340

Query: 377 PPTTP------IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 430
            PTTP       P+ PAP   K P   +   P       P P   K  +  +T   P+  
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400

Query: 431 PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490
             P     +S   P++P +P   T  +  P  P    PT   + AP  P    P  P  P
Sbjct: 401 KEPAPTTTKS--APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458

Query: 491 PPIT----PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS-SCPLPTVQIKEEALD 545
            P T     PT P    P     T+   P      +   +A  +   P PT   +E A  
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPT 517

Query: 546 DAEEPESPPPPPRSPSPEPTVVDTPSHASQSA 577
             EEP   P  P  P+P       P+   + A
Sbjct: 518 TPEEP--TPTTPEEPAPTTPKAAAPNTPKEPA 547



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 44/245 (17%), Positives = 86/245 (35%), Gaps = 15/245 (6%)

Query: 38  PASPDGRTS-----PINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92
           P +  G TS     P     + +   +P   + ++    A T  ++      E S+P  +
Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 729

Query: 93  NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSSDPKD-- 149
            +      + D    + ++    K  E    NSP E G   +    +   E ++  KD  
Sbjct: 730 KEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKT 785

Query: 150 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 209
            ++D R+T P   +     +   ++  ++  +++  A       T    + P     L T
Sbjct: 786 TERDLRTT-PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844

Query: 210 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269
               P  T    + + T ++  N+P+    P       +A    PQ+P      P  +  
Sbjct: 845 TTLAPKVTTT--KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 902

Query: 270 PPLQP 274
           P   P
Sbjct: 903 PKTMP 907



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 68/367 (18%), Positives = 119/367 (32%), Gaps = 57/367 (15%)

Query: 36  KQPA----SPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP-- 89
           K+PA    +P     P +         +P   + ++    A T  K       + ++P  
Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651

Query: 90  LKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148
           LK       K  +  E A  T+   T T  +   P +P E     +   +  +   + PK
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE-----TAPTTPKEPAPTTPK 706

Query: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP---TGVTPAPSSAPPGTP 205
                   T+P  P P  +E  + ++ ++     + P    P      TP      P  P
Sbjct: 707 K----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762

Query: 206 QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH 265
            +PT   TP+AT   P+ + TA     +    T P   T    AP +  +   +      
Sbjct: 763 GVPTT-KTPAAT--KPEMTTTAKDKTTERDLRTTPETTT---AAPKMTKETATTTEKTTE 816

Query: 266 PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
                    +T +  Q + P                              +   L P+ +
Sbjct: 817 SKITATTTQVTSTTTQDTTPFKIT------------------------TLKTTTLAPKVT 852

Query: 326 QGQAPLGTSPAAAYPHTSL----QLPASQSALQSQQPPREQPLPPA----PLAMPHIKPP 377
             +  + T+     P  +     +   S++     Q P + P  P     P  MP ++ P
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 912

Query: 378 PTTPIPQ 384
            TTP P+
Sbjct: 913 KTTPTPR 919


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  130 bits (327), Expect = 6e-30
 Identities = 138/598 (23%), Positives = 214/598 (35%), Gaps = 70/598 (11%)

Query: 29  TLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASS 88
           T +    K P   +  +   N D + +   +P  ++T  N         +AK +    S 
Sbjct: 115 TKKKPTPKPPVVDEAGSGLDNGDFKVT---TPDTSTTQHNKVSTSPKITTAKPINPRPSL 171

Query: 89  PLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148
           P  S+  +   +  + E    T    T  ++ S     ++G+ +++ ++       +  K
Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTS-----TDGKEKTTSAKETQSIEKTSAK 226

Query: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPGTPQ 206
           D+   ++  +   P  +        +  ++     P  PA   P   TP    + P TP+
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286

Query: 207 LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH------------- 253
            P P  T SA   P + +PT ++ P  P  P  P P T  + AP                
Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345

Query: 254 -PQRP-------PSPHPPPHPSPHPPLQPL---------TGSAGQPSAPSHAQPPLHGQG 296
            P++P       P+P  P  P+P  P +P          T     P+AP    P    + 
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 405

Query: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
            P      A    + P P  P    P  ++        PA     ++   P   S   ++
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465

Query: 357 QPPREQPLPPAPLAMPHIKPPPTTP------IPQLPAPQAHKHPPHLSG--PSPFSMNAN 408
           +P    P  PAP      KP PTTP       P+ PAP   K P   +   P+P +    
Sbjct: 466 EPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523

Query: 409 LPPPPA-LKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462
            P  P  L P     L+  +   P    P  L      +P P++P +P   T     P  
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583

Query: 463 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPPAGPGTSAQPPCSGAAA 521
           P    PT   + AP  P    P  P    P TP  T P+T   PA P T  +P     A 
Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA-PTTPKKPAPKELAP 642

Query: 522 SGGSIAGGSSC--PLPTVQIKEEALDDAEEPESPPPPPRSPSP------EPTVVDTPS 571
           +       ++C  P PT   K  A    +EP   P  P+ P+P       PT +  P+
Sbjct: 643 TTTKEPTSTTCDKPAPTTP-KGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPA 697



 Score =  123 bits (309), Expect = 8e-28
 Identities = 154/675 (22%), Positives = 240/675 (35%), Gaps = 112/675 (16%)

Query: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107
           +N++     + + +    +S D K +T   SAK+ +    +  K      + +A  T +A
Sbjct: 185 VNKETTVETKETTTTNKQTSTDGKEKTT--SAKETQSIEKTSAKDLAPTSKVLAKPTPKA 242

Query: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 167
           + T    TK   ++ P  P+    +   S +       +P      +  T+P  P+P   
Sbjct: 243 ETT----TKGPALTTPKEPTPTTPKEPASTT-----PKEPTPTTIKSAPTTPKEPAPTTT 293

Query: 168 ESDSDSSAQQQMLQAQPPALQAP------TGVTPAPSS--APPGTPQLPTPG-PTPSATA 218
           +S   +  +      + PA   P      T   PAP++  + P TP+ P P  P   A  
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353

Query: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGS 278
            P + +PT  + P  P  P  P P T   + PA    + P+P  P  P+P  P +P   +
Sbjct: 354 TPKEPAPTTPKEPT-PTTPKEPAPTT---KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409

Query: 279 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL-QHPGPPQPFGLP-----PQASQGQAPLG 332
             +P+  +  +P       P P + ++ P   + P P      P     P  +  + P  
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469

Query: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 389
           T+P    P T    P   +    ++P    P  PAP      KP PTTP    P  P   
Sbjct: 470 TTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTK--KPAPTTPKEPAPTTPKET 523

Query: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP----PSAHPPPLQLMPQS----- 440
           A   P  L+  +P  +    P  PA      L+   P    P+    P    P++     
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583

Query: 441 ----------QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ----------------- 473
                     +P P++P +P   T  +  P  P    PT L +                 
Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643

Query: 474 --------------------VAPQPPFAQHPFVPGGPPPITPP-TCPSTSTPPAGPGTSA 512
                                AP  P    P  P  P P TP  T P+T   PA P T  
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA-PTTPK 702

Query: 513 QPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP------ESPPPPPRSPSPEP 564
           +P     A   + G  +  S  P PT   KE A    +EP      +  P  P +P P  
Sbjct: 703 KPAPKELAPTTTKGPTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 761

Query: 565 TVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 624
           + V TP+   +    +K  D      +  +L   P   +     +E  +   K  A  K 
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDE-----STPELSAEPTPKALENSPKEPGVPTTKTPAATKP 816

Query: 625 REEREREKEKEKERE 639
            E     K+K  ER+
Sbjct: 817 -EMTTTAKDKTTERD 830



 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 120/512 (23%), Positives = 180/512 (35%), Gaps = 43/512 (8%)

Query: 95  RQREKVASDTEE--ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ 152
           ++ +K   D E   A+   +KK +T++   P  P   E  S          + D      
Sbjct: 91  KKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQH 150

Query: 153 DNRSTSPSI-------PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 205
           +  STSP I       P P     +SD+S +  +   +   ++     T    ++  G  
Sbjct: 151 NKVSTSPKITTAKPINPRP-SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 209

Query: 206 QLPTPGPTPSATAVPPQG-SPTAS-QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263
           +  +   T S      +  +PT+   A   P+A T         + PAL   + P+P  P
Sbjct: 210 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT-------TKGPALTTPKEPTPTTP 262

Query: 264 PHPSPHPPLQPL-TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322
             P+   P +P  T     P+ P    P      P  P    A    + P P  P    P
Sbjct: 263 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE-PAPTTTKEPAPTTPKEPAP 321

Query: 323 QASQGQAPLGTSPAAAYPH----TSLQLPASQSALQSQQPPREQPLPPAPL--AMPHIKP 376
             ++  AP  T  A   P     T+ + PA  +  +      ++P P  P   A    +P
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381

Query: 377 PPTTP------IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 430
            PTTP       P+ PAP   K P   +   P       P P   K  +  +T   P+  
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441

Query: 431 PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490
             P     +S   P++P +P   T  +  P  P    PT   + AP  P    P  P  P
Sbjct: 442 KEPAPTTTKS--APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499

Query: 491 PPIT----PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS-SCPLPTVQIKEEALD 545
            P T     PT P    P     T+   P      +   +A  +   P PT   +E A  
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPT 558

Query: 546 DAEEPESPPPPPRSPSPEPTVVDTPSHASQSA 577
             EEP   P  P  P+P       P+   + A
Sbjct: 559 TPEEP--TPTTPEEPAPTTPKAAAPNTPKEPA 588



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 44/245 (17%), Positives = 86/245 (35%), Gaps = 15/245 (6%)

Query: 38  PASPDGRTS-----PINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92
           P +  G TS     P     + +   +P   + ++    A T  ++      E S+P  +
Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 770

Query: 93  NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSSDPKD-- 149
            +      + D    + ++    K  E    NSP E G   +    +   E ++  KD  
Sbjct: 771 KEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKT 826

Query: 150 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 209
            ++D R+T P   +     +   ++  ++  +++  A       T    + P     L T
Sbjct: 827 TERDLRTT-PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 885

Query: 210 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269
               P  T    + + T ++  N+P+    P       +A    PQ+P      P  +  
Sbjct: 886 TTLAPKVTTT--KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 943

Query: 270 PPLQP 274
           P   P
Sbjct: 944 PKTMP 948



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 68/367 (18%), Positives = 119/367 (32%), Gaps = 57/367 (15%)

Query: 36  KQPA----SPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP-- 89
           K+PA    +P     P +         +P   + ++    A T  K       + ++P  
Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692

Query: 90  LKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148
           LK       K  +  E A  T+   T T  +   P +P E     +   +  +   + PK
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE-----TAPTTPKEPAPTTPK 747

Query: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP---TGVTPAPSSAPPGTP 205
                   T+P  P P  +E  + ++ ++     + P    P      TP      P  P
Sbjct: 748 K----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803

Query: 206 QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH 265
            +PT   TP+AT   P+ + TA     +    T P   T    AP +  +   +      
Sbjct: 804 GVPTT-KTPAAT--KPEMTTTAKDKTTERDLRTTPETTT---AAPKMTKETATTTEKTTE 857

Query: 266 PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
                    +T +  Q + P                              +   L P+ +
Sbjct: 858 SKITATTTQVTSTTTQDTTPFKIT------------------------TLKTTTLAPKVT 893

Query: 326 QGQAPLGTSPAAAYPHTSL----QLPASQSALQSQQPPREQPLPPA----PLAMPHIKPP 377
             +  + T+     P  +     +   S++     Q P + P  P     P  MP ++ P
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 953

Query: 378 PTTPIPQ 384
            TTP P+
Sbjct: 954 KTTPTPR 960


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  124 bits (311), Expect = 4e-28
 Identities = 133/459 (28%), Positives = 156/459 (33%), Gaps = 68/459 (14%)

Query: 111 SSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 170
           SS +   +++S+  SPS   G   + +    +G + P+     +    P  P PQ     
Sbjct: 14  SSAQNLNEDVSQEESPSLIAG---NPQGAPPQGGNKPQG--PPSPPGKPQGPPPQGGNQP 68

Query: 171 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTAS-- 228
                     Q  PP      G        PPG PQ P P    S +   P G P     
Sbjct: 69  QGPPPPPGKPQGPPPQ-----GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 123

Query: 229 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288
           Q  NQPQ P  P P    Q  P     +P  P PP  P   PP        G   + S  
Sbjct: 124 QGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-------QGDNKSRSSR 174

Query: 289 QPPLHGQGPPGPHSLQAGPLLQHPGPP--QPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 346
            PP   QGPP     Q G   Q P PP  +P G PPQ        G  P    P    Q 
Sbjct: 175 SPPGKPQGPPP----QGGNQPQGPPPPPGKPQGPPPQG-------GNKPQGPPPPGKPQG 223

Query: 347 PASQSALQSQQ---PPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPF 403
           P  Q   +SQ    PP +   PP         PPP    PQ P PQ    P    GP P 
Sbjct: 224 PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---QGPPPP 280

Query: 404 SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463
                 PP    K  SS S    P   PP      Q    P  P  PPG  Q    PPP 
Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQGPPP------QGGNQPQGPPPPPGKPQG---PPPQ 331

Query: 464 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523
             + P G     P PP       P GPPP       S  +PP  P     P   G    G
Sbjct: 332 GGNKPQG-----PPPPGK-----PQGPPPQGGSKSRSARSPPGKP--QGPPQQEGNNPQG 379

Query: 524 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562
                G +   P           A +P+ PP PP+   P
Sbjct: 380 PPPPAGGNPQQPQAP-------PAGQPQGPPRPPQGGRP 411



 Score =  124 bits (310), Expect = 6e-28
 Identities = 128/429 (29%), Positives = 148/429 (34%), Gaps = 69/429 (16%)

Query: 160 SIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 219
           ++ S Q+   D        ++   P       G  P    +PPG PQ P           
Sbjct: 12  ALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP----------- 60

Query: 220 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 279
           PPQG        NQPQ P  P P    Q  P     +P  P PP  P   PP    + S 
Sbjct: 61  PPQGG-------NQPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 111

Query: 280 GQPSAPSHAQPPLHG---QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG--TS 334
             P       PP  G   QGPP P     GP  Q    PQ    PP   QG  P G   S
Sbjct: 112 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-PPPPGKPQGPPPQGDNKS 170

Query: 335 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP--PPTTPIPQLPAPQ--- 389
            ++  P    Q P  Q   Q Q PP     P  P      KP  PP    PQ P PQ   
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 230

Query: 390 ----AHKHPPHLSGPSPFSMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 444
               A   P    GP P   N    PPPP  K          P   PP     PQ  P P
Sbjct: 231 KSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK----------PQGPPPQGGNKPQGPPPP 280

Query: 445 SSPAQPP----GLTQSQNLPP-PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP 499
             P  PP      ++S   PP  P   PP G +Q    PP    P  P GPP       P
Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPP-------P 330

Query: 500 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--- 556
                P GP    +P   G    GGS +  +  P    Q   +   +   P+ PPPP   
Sbjct: 331 QGGNKPQGPPPPGKP--QGPPPQGGSKSRSARSPPGKPQGPPQ--QEGNNPQGPPPPAGG 386

Query: 557 -PRSPSPEP 564
            P+ P   P
Sbjct: 387 NPQQPQAPP 395



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 106/364 (29%), Positives = 126/364 (34%), Gaps = 92/364 (25%)

Query: 213 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 272
           +PS  A  PQG+P   Q  N+PQ P +P             P +P  P P     P  P 
Sbjct: 28  SPSLIAGNPQGAPP--QGGNKPQGPPSP-------------PGKPQGPPPQGGNQPQGPP 72

Query: 273 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 332
            P     G+P  P    PP  G  P GP           P P +P G PPQ  + ++P  
Sbjct: 73  PP----PGKPQGP----PPQGGNKPQGP-----------PPPGKPQGPPPQGDKSRSPRS 113

Query: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 392
                  P    Q P  Q   Q Q PP                PPP  P  Q P PQ   
Sbjct: 114 -------PPGKPQGPPPQGGNQPQGPP----------------PPPGKP--QGPPPQGGN 148

Query: 393 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 452
            P    GP P       PP    K  SS S    P   PP      Q    P  P  PPG
Sbjct: 149 KP---QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP------QGGNQPQGPPPPPG 199

Query: 453 LTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSA 512
             Q    PPP   + P G     P PP       P GPPP       S  +PP  P    
Sbjct: 200 KPQG---PPPQGGNKPQG-----PPPPGK-----PQGPPPQGDNKSQSARSPPGKP--QG 244

Query: 513 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSH 572
            PP  G    G         P P  + +        +P+ PPPP + P   P    + S 
Sbjct: 245 PPPQGGNQPQGP--------PPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSR 295

Query: 573 ASQS 576
           +S+S
Sbjct: 296 SSRS 299



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 41/146 (28%), Positives = 49/146 (33%), Gaps = 18/146 (12%)

Query: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185
           P +G  +S  SRS   +    P       +   P    PQ       +  Q      +P 
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346

Query: 186 ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SPTASQAPNQPQAPTAPVPHT 244
                 G     + +PPG PQ P     P      PQG  P A   P QPQAP       
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQGP-----PQQEGNNPQGPPPPAGGNPQQPQAP------- 394

Query: 245 HIQQAPALHPQRPPSPHPPPHPSPHP 270
                PA  PQ PP P     PS  P
Sbjct: 395 -----PAGQPQGPPRPPQGGRPSRPP 415


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score =  122 bits (306), Expect = 2e-27
 Identities = 140/485 (28%), Positives = 188/485 (38%), Gaps = 59/485 (12%)

Query: 117 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQ 176
           T   SR + P  G+  + +  ++       PK       S  P  P P   E+     A 
Sbjct: 366 TPVCSRFSPPEPGDTPTDEPDALYVACQGQPKG--GHVTSMQPKEPGPLQCEAKPLGKAG 423

Query: 177 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236
            Q+     P L+AP      P   PP    L +P P  S T+ PP+ S  +   P   + 
Sbjct: 424 VQL----EPQLEAPLN-EEMPLLPPPEESPL-SPPPEESPTSPPPEASRLS---PPPEEL 474

Query: 237 PTAPVPHT-HIQQAPALHPQRPP---SP-HPPPHPSPHPPLQPLTGSAGQPSAPSHA-QP 290
           P +P+P   H+ +     P  PP   SP  PPP  SP  PL+    S  + S PS A + 
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534

Query: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP----PQASQGQAPLGTSPAAAYPHTSLQL 346
           PL    PP   S  + P  + P  P P  LP    P+AS+   P   SP +  P  S   
Sbjct: 535 PL---SPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591

Query: 347 PASQSAL--------QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 398
           P  +++             PP E PL P P A     PP  +P+   P       PP +S
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651

Query: 399 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP------PPLQLMPQSQPLPSSPAQPP- 451
             SP  + + L PPP   PLS      P S  P      PP +  P S P   SPA PP 
Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711

Query: 452 -------GLTQSQNLPPP--PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502
                   L +S  LP P  P   P +    ++P+P   + P +   P P  P   P   
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP---EEPHL--SPRPEEPHLSPQAE 766

Query: 503 TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD-DAEEPESPPPPPR--- 558
            P   P    + PC  A      ++  +  P  + Q +E  L    EEP   P P     
Sbjct: 767 EPHLSP--QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824

Query: 559 SPSPE 563
           SP PE
Sbjct: 825 SPQPE 829



 Score =  120 bits (300), Expect = 8e-27
 Identities = 208/775 (26%), Positives = 288/775 (37%), Gaps = 102/775 (13%)

Query: 247  QQAPALHPQRPPSPHPPPHPSPHPPL-----QPLTG--SAGQPSAPSHAQPPLHGQGPP- 298
            Q  P      PP P   P   P         QP  G  ++ QP  P     PL  +  P 
Sbjct: 364  QHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG----PLQCEAKPL 419

Query: 299  GPHSLQAGPLLQHP-GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL------QLPASQ- 350
            G   +Q  P L+ P     P   PP+ S    P   SP +  P  S       +LPAS  
Sbjct: 420  GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479

Query: 351  -SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL 409
              AL   +P  E PL P P   P   PP ++P    P  ++   PP  S PSP ++   L
Sbjct: 480  PEALHLSRPLEESPLSPPPEESPLSPPPESSPFS--PLEESPLSPPEESPPSP-ALETPL 536

Query: 410  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP---PASH 466
             PPP   PLS      P S  PPP +L P S P  +S   PP   +S   PPP   P S 
Sbjct: 537  SPPPEASPLSPPFEESPLS--PPPEEL-PTSPPPEASRLSPPP-EESPMSPPPEESPMSP 592

Query: 467  PPTGLHQVAPQPPFAQHPFVPGGPP---PITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523
            PP         PPF + P  P  PP   P++PP   S  +PP      + PP     +  
Sbjct: 593  PPEASRLF---PPFEESPLSP--PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647

Query: 524  GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSPSPEPTVVDTPSHASQSARFYK 581
              ++  S  PLP V       +  E P SPPP   P SP PE + +  P   S ++    
Sbjct: 648  PEVSRLS--PLPVVSRLSPPPE--ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP--P 701

Query: 582  HLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERE 641
              D   +      L  +PL  S L    EE     + E    +    E       E    
Sbjct: 702  PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE---- 757

Query: 642  REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRT 701
                              E  LS PQ   P H+ P  E P        P++ P       
Sbjct: 758  ------------------EPHLS-PQAEEP-HLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797

Query: 702  LSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIR 761
              +    H+   T   H   +   P +P L+   P   ++ P   E  L  R   E  + 
Sbjct: 798  SPQPEELHLSPQTEEPH---LSPVPEEPCLS-PQPEESHLSPQSEEPCLSPRP-EESHLS 852

Query: 762  ERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAG-PHPFASFHPGLNPL 820
                +  + P  E KPPE     PA   +  F      ++ P  G P       P L+PL
Sbjct: 853  PELEKPPLSPRPE-KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911

Query: 821  ERE-RLALAG-PQLRPEMSYPDRL---AAERIHAERMASLTSDPLARLQM-FNVTPHHHQ 874
              E  L+ +G P L P++  PD L    +  I A    +L+  PL  L+  F        
Sbjct: 912  PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS--PLGELEYPFGAKGDSDP 969

Query: 875  HSHIHSHLHLHQQDPLHQGSA---GPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPH 931
             S + + +      P  + +     PV P++ P + G  +   P  P  L  PL   PP 
Sbjct: 970  ESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVG--PASP-ILMEPL---PPQ 1023

Query: 932  EHEMLRH---PVFGTP---YPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQ 980
               +L+H   P    P    P  LP ++P P+S   ++  + +  AEL  +  E+
Sbjct: 1024 CSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV-SDEAELHEMETEK 1077



 Score =  104 bits (260), Expect = 4e-22
 Identities = 155/623 (24%), Positives = 213/623 (34%), Gaps = 108/623 (17%)

Query: 35   KKQPASPDGRTSPINEDIRSSG----RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPL 90
            ++ P SP    SP++    SS       SP +    S  S A     S        S P 
Sbjct: 490  EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549

Query: 91   KSNKRQ---REKVASDTEEADRTS-----SKKTKTQEISRPNSPSEGEG------ESSDS 136
            + +       E   S   EA R S     S  +   E S  + P E         ES  S
Sbjct: 550  EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLS 609

Query: 137  RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML-------QAQPPALQA 189
                +   S P +  + +     S  SP   ES      +   L       +  PP  ++
Sbjct: 610  PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669

Query: 190  PTGVTP--APSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP-------QAPTAP 240
            P    P  +P+S PP   +L +P P  S T+ PP+ SP AS  P          ++P  P
Sbjct: 670  PLSPPPEESPTSPPPEASRL-SPPPEDSPTSPPPEDSP-ASPPPEDSLMSLPLEESPLLP 727

Query: 241  VPHTHI----QQAPALHPQRPPSPHPPPHPS-PH-------PPLQPLTGSAGQPSAPSHA 288
            +P         + P L P RP  PH  P P  PH       P L P        + P   
Sbjct: 728  LPEEPQLCPRSEGPHLSP-RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786

Query: 289  QPPLHGQGP---PGPHSLQAGPLLQHPG----PPQPFGLP-PQAS----QGQAPLGTSPA 336
                  +GP   P P  L   P  + P     P +P   P P+ S    Q + P   SP 
Sbjct: 787  HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPC-LSPR 845

Query: 337  AAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP------------------- 377
                H S +L     + + ++PP E    PAP  +P   PP                   
Sbjct: 846  PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905

Query: 378  -PTTPIPQLPAPQAHKHPPHLSG--------PSPFSMNANLPPPPALKPLSSLSTHHPPS 428
             P +P+P+   P +    P LS         P P S       PPAL PL  L   +P  
Sbjct: 906  PPLSPLPE-ELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE--YPFG 962

Query: 429  AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP-PPASHPPTGLHQVAPQPPFAQHPFVP 487
            A        P + P+  +P  PP      +  P PP   PP+    V P  P    P   
Sbjct: 963  AKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL-- 1020

Query: 488  GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG-----GSIAGGSSCPLPTVQIKEE 542
               PP   P    +  P   P +   PP    +        G + G S       ++ E 
Sbjct: 1021 ---PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD----EAELHEM 1073

Query: 543  ALDDAEEPESPPPPPRSPSPEPT 565
              +   EPE P   P + SP P+
Sbjct: 1074 ETEKVSEPECPALEPSATSPLPS 1096



 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 162/714 (22%), Positives = 256/714 (35%), Gaps = 127/714 (17%)

Query: 70   SKAETVKKSAKKVKEEASSPL---KSNKRQREKVASDTEEADRTSSKKTKTQEISR---- 122
            S+ + + K  +KV     +P      + R   ++    ++A+   +K+TK  +I+R    
Sbjct: 2040 SRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDR 2099

Query: 123  --------PNSPSEGEGESSDSRSVNDEGSSDPKDI----DQDNRSTSPSIPSPQDNESD 170
                    P   + G    + + ++     + P  +    D   +  + S+P P D+  +
Sbjct: 2100 PALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGP-DSPGE 2158

Query: 171  SDSSAQQQMLQAQPPALQAPTGVTPAPS------SAPPGTPQLPTPGPTPS------ATA 218
                   Q+  AQ P+ Q P G+ PA        +APP  P  P+P   P+      A++
Sbjct: 2159 LFLKLPPQV-PAQVPS-QDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASS 2216

Query: 219  VPPQGSPTA--SQAPNQPQ-APTAPVPHTHIQQAPALH----PQRP---------PSPHP 262
             P  G P    +  P  P+  P+ P P     + P+L     P+ P         P   P
Sbjct: 2217 RPGAGQPGEFHTTPPGTPRHQPSTPDPFLK-PRCPSLDNLAVPESPGVGGGKASEPLLSP 2275

Query: 263  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPH----SLQAGPLLQHPGPPQ 316
            PP       L+      G  S+PS+  P L     P  G H     L+   + + P  P+
Sbjct: 2276 PPFGESRKALEVKKEELG-ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR 2334

Query: 317  PFGLPPQA-SQGQAPLGTSPAAAY-----PHTSLQLPASQSALQSQQP--PREQPLPPAP 368
               + PQ+   G  P    PA A       H  +  P S +   +Q P  PR QP PP  
Sbjct: 2335 ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES 2394

Query: 369  LAMPHIKPPPTTPIPQLPA-PQAHKHPPHLSGPSPFSMNANLPPP-------------PA 414
                  +  P+ P  ++PA PQ+         P P S  A  P P             P 
Sbjct: 2395 CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454

Query: 415  LKPLSS---LSTHHPPSAHPPPLQLMPQS------------QPLPSSPAQPPGLTQSQNL 459
             +P S       H PP   PP +     S              LP+ PA           
Sbjct: 2455 SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ 2514

Query: 460  PPPPASHPPTGLHQVAPQPPFAQHPFVPGGP---PPITPPTCPSTSTPP------AGPG- 509
            PP     P TG     P P     P   G P   PP+  P  P    PP       GPG 
Sbjct: 2515 PPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLP----PPHGINSHFGPGP 2570

Query: 510  TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDT 569
            T  +P  +    + G+     S   P+     E+      P  PP     P+P+ ++   
Sbjct: 2571 TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESY--GLSPLRPPSVLPPPAPDGSLPYL 2628

Query: 570  PSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERE 629
               ASQ +     +++      R D       G+ +      A     ++       + E
Sbjct: 2629 SHGASQRSGITSPVEK------RED------PGTGMGSSLATAELPGTQDPGMSGLSQTE 2676

Query: 630  REKEKEKERERE----REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 679
             EK+++++R RE    ++ +R   R  K +++A  G +  P   G     P+FE
Sbjct: 2677 LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730



 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 94/333 (28%), Positives = 119/333 (35%), Gaps = 54/333 (16%)

Query: 143  GSSDPKDIDQDNRSTSPSIP----SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 198
            G      +   + S + S+P     P  +  D   S  Q +L  Q P L+ P        
Sbjct: 4112 GGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTG-- 4169

Query: 199  SAPPGTPQLPTPGPT-PSATAVPPQG-SPTASQAPNQPQAPTAPVPH-THI-----QQAP 250
                  PQ P PGP   S   +P  G  PT  Q   Q Q   A  P   H+     QQ  
Sbjct: 4170 ------PQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223

Query: 251  ALHPQRPPSP-----HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 305
            AL  QR           PP+  P     PL G  G        QP L G   PGP   Q 
Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLG-------CQPQLGGF--PGP---QT 4271

Query: 306  GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-----TSLQLPASQSAL--QSQQP 358
            GPL +    P+P G PP+       L T P     H     +S Q P   S L   S Q 
Sbjct: 4272 GPLQELGAGPRPQG-PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330

Query: 359  PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL--SGPSPFSMNANL-----PP 411
            P E  LPP     P  + P   P P   +P A +    L   G  P+    NL     P 
Sbjct: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390

Query: 412  PPALKP--LSSLSTHHPPSAHPPPLQLMPQSQP 442
              +L P  L  ++    P A    ++  P+ +P
Sbjct: 4391 QSSLVPGHLDQVNGQVVPEASQLSIKQEPREEP 4423



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 88/335 (26%), Positives = 126/335 (37%), Gaps = 63/335 (18%)

Query: 404  SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN--LPP 461
            +++  +PP P        +   PP A  P + +         SP  P GL+ S +  L P
Sbjct: 2101 ALHLRIPPQPG-------ALGSPPPAAAPTIFI--------GSPTTPAGLSTSADGFLKP 2145

Query: 462  PPASHP-------------PTGLHQVAPQPPFAQHPFVPGGPP-PITPPTCPSTSTPPAG 507
            P  S P             P    QV  Q PF   P  P  P  P  PPT P   +P   
Sbjct: 2146 PAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA 2205

Query: 508  PGTSAQPPCSGAAASGGSIAGGS-------------SCPLPTVQIKEEALDDAEEPESPP 554
            P   AQPP  GA++  G+   G              S P P ++ +  +LD+   PESP 
Sbjct: 2206 P---AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262

Query: 555  PPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR--TDLYFM--PLAGSKLAKKRE 610
                  S EP +   P   S+ A   K  + G +S +    +L F+  P +G+ L     
Sbjct: 2263 VGGGKAS-EPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLG---- 2317

Query: 611  EAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE-----GRLSD 665
              +E    +  +     R  + E +      R +E    +A   S  +H      G  +D
Sbjct: 2318 -GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376

Query: 666  PQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALR 700
            P    P   RP   PPP +  A+PP   P  P  R
Sbjct: 2377 PYAQPPLTPRPQ-PPPPESCCALPPRSLPSDPFSR 2410



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 96/344 (27%), Positives = 122/344 (35%), Gaps = 54/344 (15%)

Query: 266  PSPHP--PLQPLTGSAGQPSAPSHAQPPLHG---------QGPPGPHSLQAGPLLQHPGP 314
            PS H   PL   T      + P   +P L G         Q  P P SLQ  P L+ PG 
Sbjct: 4041 PSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQ 4100

Query: 315  PQP----FGLPPQASQGQAPLGTSP-AAAYPHTSLQLPAS---------QSALQSQQPPR 360
             Q            S GQ   G+S  A++ PH   Q   S         Q+ L  QQP  
Sbjct: 4101 QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPML 4160

Query: 361  EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-LS 419
            E+P+        +  P P  P P L + Q    P     P+   + A L    A  P L 
Sbjct: 4161 ERPM------QNNTGPQPPKPGPVLQSGQGL--PGVGIMPTVGQLRAQLQGVLAKNPQLR 4212

Query: 420  SLSTHHPPSAHPPPLQL-MPQSQPLPSSPA-QPPGLTQSQNLPPPPASHPPTGLH---QV 474
             LS           +Q  + QSQ +  +P  Q PG TQ+  L       P  G     Q 
Sbjct: 4213 HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG-TQTSPLQGLLGCQPQLGGFPGPQT 4271

Query: 475  APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 534
             P       P  P GPP +  P    ++ P  GP     PP S       S     S  L
Sbjct: 4272 GPLQELGAGPR-PQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330

Query: 535  PTVQIKEEALDDAEEPESPPPPPRSPSPE-PTVVDTPSHASQSA 577
            PT            E + PP  P +P P+ PT+   P   S +A
Sbjct: 4331 PT------------EAQLPPTHPGTPKPQGPTLEPPPGRVSPAA 4362



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 96/363 (26%), Positives = 120/363 (33%), Gaps = 58/363 (15%)

Query: 157  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ-----LPTPG 211
            T+P   + +  E     S   Q+L  QP     P+ +   P    PG  Q     L T G
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112

Query: 212  PTPSATAVPPQGSPTASQAPN---QPQAPTAPVPHTHIQQAPALHPQRPPSPHP------ 262
               S   +    S  AS  P+   QP       P +  Q    L PQ+P    P      
Sbjct: 4113 GG-SHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNL--LGPQQPMLERPMQNNTG 4169

Query: 263  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322
            P  P P P LQ   G  G    P+  Q     QG      L   P L+H  P Q      
Sbjct: 4170 PQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGV-----LAKNPQLRHLSPQQQ----- 4219

Query: 323  QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-LPPAPL-----AMPHI-- 374
               Q QA L            +Q    QS    Q PP ++P    +PL       P +  
Sbjct: 4220 --QQLQALL------------MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGG 4265

Query: 375  -KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 433
               P T P+ +L A    + PP L  P        L   P L P+        P     P
Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPPRLPAPP-----GALSTGPVLGPVHPTPPPSSPQEPKRP 4320

Query: 434  LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 493
             QL   S  LP+  AQ P        P  P   PP G  +V+P            G  P 
Sbjct: 4321 SQLPSPSSQLPTE-AQLPPTHPGTPKPQGPTLEPPPG--RVSPAAAQLADTLFSKGLGPW 4377

Query: 494  TPP 496
             PP
Sbjct: 4378 DPP 4380



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 71/252 (28%), Positives = 83/252 (32%), Gaps = 40/252 (15%)

Query: 173  SSAQQQMLQA--QPPALQAPTGVTPAPSSAPPGTPQLPTPGPT---PSATAVP-PQGSPT 226
            S  QQQ LQA      LQ    V   P    PGT   P  G     P     P PQ  P 
Sbjct: 4215 SPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL 4274

Query: 227  AS--QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284
                  P     P  P P   +   P L P  P     PP  SP  P +P      Q  +
Sbjct: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPT----PPPSSPQEPKRP-----SQLPS 4325

Query: 285  PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 344
            PS +Q P   Q PP            HPG P+P G   +   G+     SPAAA    +L
Sbjct: 4326 PS-SQLPTEAQLPP-----------THPGTPKPQGPTLEPPPGR----VSPAAAQLADTL 4369

Query: 345  QLPA-----SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 399
                         L   Q P +  L P  L   + +  P     QL   Q  +  P   G
Sbjct: 4370 FSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEA--SQLSIKQEPREEPCALG 4427

Query: 400  PSPFSMNANLPP 411
                   AN  P
Sbjct: 4428 AQSVKREANGEP 4439



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 96/431 (22%), Positives = 144/431 (33%), Gaps = 67/431 (15%)

Query: 38   PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 97
            P  PD  +  + ++  S+    PS+   +   S  + +       +E    P  +     
Sbjct: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAAS--- 4657

Query: 98   EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 157
               A D+E A R +S+      ++   +P   + E  D R  +DE S  P  I   +   
Sbjct: 4658 ---ARDSERALRDTSEVKSLDLLAALPTPPHNQTE--DVRMESDEDSDSPDSIVPASSPE 4712

Query: 158  S------PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 211
            S      P  P       + +  A   ++   P A      +   P + P G   L  PG
Sbjct: 4713 SILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRA-----SIPVFPDTKPYGALGLEVPG 4767

Query: 212  PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPS-----PHPPPHP 266
              P  T    +GS  +        A    +    +  A  L  + P S     P  P   
Sbjct: 4768 KLPVTTWEKGKGSEVSVML-TVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARA 4826

Query: 267  SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP-GPHSLQAGPLLQHPGPPQPFGLPPQAS 325
               P         G+   P   +  L G+ P  GP  L+    +  PG    + L  Q  
Sbjct: 4827 GTEP-------KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVL-PG----YTLKSQLD 4874

Query: 326  QGQAPLGTSPAAAYP--HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 383
                    SPA   P  H+     ++    Q   PP E+P PP     P    PPT P+ 
Sbjct: 4875 ILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLV 4934

Query: 384  QLPA-PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 442
            +LP  P A                   PP P+  PL+S     P SA P P    P+   
Sbjct: 4935 ELPTEPLAE------------------PPVPSPLPLAS----SPESARPKPRARPPEE-- 4970

Query: 443  LPSSPAQPPGL 453
                 ++PP L
Sbjct: 4971 --GEDSRPPRL 4979



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 103/426 (24%), Positives = 149/426 (34%), Gaps = 61/426 (14%)

Query: 14   GKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDI-RSSGRNSPSAASTSSNDSKA 72
            G  S  T  S G +S LR      P +PDG    ++    + SG  SP            
Sbjct: 2595 GPSSGSTGESYG-LSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMG 2653

Query: 73   ETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT----QEISRPNSPSE 128
             ++          A++ L   +       S TE   +   ++ +     Q+I R     E
Sbjct: 2654 SSL----------ATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQE 2703

Query: 129  GEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 188
             E  ++ + +V   GS   +        +SP+       ++    +  +  L   PP+  
Sbjct: 2704 KETAAAAAGAVGPPGSWGAEP-------SSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKL 2756

Query: 189  APTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTASQAPNQ--PQAPTAPVPHTH 245
            +  G    P S P       P P  TPS+  V  +     SQA  Q  P   + P+    
Sbjct: 2757 S--GPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQ 2814

Query: 246  IQ-----QAPALHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 299
             Q     QA A    R   S   P  P P    Q L    G P A    + P  G+  PG
Sbjct: 2815 QQLWQQQQATAATSMRFAMSARFPSTPGPELGRQAL----GSPLAGISTRLPGPGEPVPG 2870

Query: 300  P----------HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          H++Q G  L   G P P   PPQ  +        P +  PH  L     
Sbjct: 2871 PAGPAQFIELRHNVQKG--LGPGGTPFPGQGPPQRPRFY------PVSEDPHR-LAPEGL 2921

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP-QAHKHPP---HLSGPSPFSM 405
            +    S  PP++   PPAP     + P P T  P LP   +    PP    L  P+P ++
Sbjct: 2922 RGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLAL 2981

Query: 406  NANLPP 411
             A   P
Sbjct: 2982 EAGKLP 2987



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 98/393 (24%), Positives = 134/393 (34%), Gaps = 68/393 (17%)

Query: 147  PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ 206
            P  +    +S  P    P   +S    +   +  + QPP +    G     S    G P 
Sbjct: 2437 PSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPA 2496

Query: 207  LPTPGPTPSATAVPPQGSPTASQAPNQPQAP--------TAPVPHTHIQQA--PALHPQR 256
                GP     A  P G P     PN  ++P         +P+  T  Q    P+L P  
Sbjct: 2497 ALPAGPAGELHAKVPSGQP-----PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV 2551

Query: 257  PPSPHPPPH-------PSP-----------------HP---PLQPLTGSAGQPSAPSHAQ 289
            P    PPPH       P P                 HP   PL P +GS G+    S  +
Sbjct: 2552 PQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLR 2611

Query: 290  PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP---LGTSPAAA-YPHTSLQ 345
            PP     PP P    + P L H G  Q  G+     + + P   +G+S A A  P T  Q
Sbjct: 2612 PP-SVLPPPAPDG--SLPYLSH-GASQRSGITSPVEKREDPGTGMGSSLATAELPGT--Q 2665

Query: 346  LPASQSALQSQ-QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 404
             P      Q++ +  R++      L    I+        +  A  A    P      P S
Sbjct: 2666 DPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGP------PGS 2719

Query: 405  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ---NLPP 461
              A  P  PA + LS   T    +     L  +P S+   S P   PG   S    + PP
Sbjct: 2720 WGAE-PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSK--LSGPILGPGSFPSDDRLSRPP 2776

Query: 462  PPASHPPTGLHQ---VAPQPPFAQHPFVPGGPP 491
            PPA+     ++    V     F Q    PG  P
Sbjct: 2777 PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLP 2809



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 81/433 (18%), Positives = 157/433 (36%), Gaps = 64/433 (14%)

Query: 323  QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP--------LPPAPLAMPHI 374
            Q  Q  A L  SP+ + P    +LP         QPP+  P        L P  +A+P  
Sbjct: 3609 QQQQHSAVLALSPSQS-PRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQ 3667

Query: 375  KPPP--TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP-----PPPALKPLSSLSTHHPP 427
               P   T + Q    Q       L+GPS      NL      P   L     L      
Sbjct: 3668 PGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQR 3727

Query: 428  SAHPPPLQLMPQSQP----------LPSSPAQPPGLTQSQNLPP------PPASHPPTGL 471
                  LQ   Q Q           +     Q PG+  +Q L P      PP+SH    +
Sbjct: 3728 MQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLV 3787

Query: 472  HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG-----TSAQPPCSGAAASGGSI 526
             Q++PQPP      +      +     P  +  P GP      T ++   S   A  G  
Sbjct: 3788 QQLSPQPPQGPQGMLGPAQVAVLQQQHPG-ALGPQGPHRQVLMTQSRVLSSPQLAQQGQ- 3845

Query: 527  AGGSSCPLPTVQIKEEALDDAEEPESP-----PPPPRSPSPEPTVVDTPSHASQSARFYK 581
             G     L T Q +++     ++              S S +P +   P  + Q  +  +
Sbjct: 3846 -GLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ 3904

Query: 582  HLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERE 641
             L +                  +L +++++ +++ ++  +Q+ ++++++++ +++++++ 
Sbjct: 3905 QLQQ----------------QQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQL 3948

Query: 642  REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRT 701
            ++++++ ++  +      + +    Q+      R    P       V   +GP  PA + 
Sbjct: 3949 QQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVA--LGPGMPA-KP 4005

Query: 702  LSEYARPHVMSPT 714
            L  ++ P  + PT
Sbjct: 4006 LQHFSSPGALGPT 4018



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 75/365 (20%), Positives = 112/365 (30%), Gaps = 49/365 (13%)

Query: 190  PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 249
            PT  +  P + PP   Q    G TPS           +++   +    T+ V    +  A
Sbjct: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679

Query: 250  PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP---LHGQGPPGPHSLQAG 306
                         PPH             +  P +   A  P   L  + P  PH L +G
Sbjct: 4680 LPT----------PPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPH-LGSG 4728

Query: 307  -------------PLLQHPGPP-----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA 348
                         PL+     P     +P+G       G+ P+ T         S+ L  
Sbjct: 4729 RWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTV 4788

Query: 349  SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408
            S +A ++             + +P+         P     +  K      G     +   
Sbjct: 4789 SAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGK 4848

Query: 409  LPP--PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL------- 459
             P   P  LK   ++   +   +    L L+ Q  P P  P Q        NL       
Sbjct: 4849 SPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA 4908

Query: 460  PPPPASHPPTGLHQVAPQP------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 513
            PPP    PP     +AP P      P  + P  P   PP+  P   ++S   A P   A+
Sbjct: 4909 PPPEEPSPPPS--PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966

Query: 514  PPCSG 518
            PP  G
Sbjct: 4967 PPEEG 4971



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 68/300 (22%), Positives = 96/300 (32%), Gaps = 42/300 (14%)

Query: 177  QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236
            +Q +Q      +  T    A +  PPG+      G  PS+ A           A  Q ++
Sbjct: 2692 RQQIQRNTLRQEKETAAAAAGAVGPPGSW-----GAEPSSPAFEQLSRGQTPFAGTQDKS 2746

Query: 237  PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
                +P + +   P L P   PS      P P             P+ PS          
Sbjct: 2747 SLVGLPPSKLS-GPILGPGSFPSDDRLSRPPP-------------PATPSSMDV------ 2786

Query: 297  PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
                  L  G    +   P P  LP Q  Q Q        AA   TS++   S     + 
Sbjct: 2787 --NSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA---TSMRFAMSARFPSTP 2841

Query: 357  QPPREQPLPPAPLAMPHIK-PPPTTPIPQLPAPQAHKHPPHL------SGPSPFSMNANL 409
             P   +    +PLA    + P P  P+P    P       H        G +PF      
Sbjct: 2842 GPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFP-GQGP 2900

Query: 410  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469
            P  P   P+S      P    P  L+ +  S   P  P+ PP    + +L P P +  PT
Sbjct: 2901 PQRPRFYPVSE----DPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPT 2956



 Score = 34.7 bits (78), Expect = 0.47
 Identities = 40/145 (27%), Positives = 52/145 (35%), Gaps = 31/145 (21%)

Query: 304  QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 363
            Q   LL  PGP Q   LP +        G+SP+ A     L L        ++QP   QP
Sbjct: 3281 QQHSLLSAPGPAQAMSLPHE--------GSSPSLAGSQQQLSL----GLAGARQPGLPQP 3328

Query: 364  LPPAPLAMPHIKPPPTTPIPQLPAP-------QAHKHPPHLSGPSPFSMNANLPPPPALK 416
            L P          PP   + Q  AP       Q H       G +      +  P  + K
Sbjct: 3329 LMPT--------QPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQK 3380

Query: 417  PLSSLSTHHPPSAHPPPLQLMPQSQ 441
            P+ ++    PPS    P QL  Q Q
Sbjct: 3381 PMGTM----PPSMCMKPQQLAMQQQ 3401



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 21/97 (21%)

Query: 263  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322
            P  P P  P QP   +  Q  APS A     G    G H  QAG             +P 
Sbjct: 3323 PGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGL------------VPQ 3370

Query: 323  QASQ---GQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
            Q+SQ    Q P+GT P       S+ +   Q A+Q Q
Sbjct: 3371 QSSQPVLSQKPMGTMP------PSMCMKPQQLAMQQQ 3401



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 38/151 (25%), Positives = 59/151 (39%), Gaps = 22/151 (14%)

Query: 160  SIPSPQD---------NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP 210
            S+PSP           +E++      +++ + + PAL+ P+  +P PS  P G    P P
Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE-PSATSPLPS--PMGDLSCPAP 1106

Query: 211  GPTPSATAVPPQGSPTAS----QAP-NQPQAPTAPVP-HTHIQQAPALHPQRPPSPHPPP 264
             P P+       G  TA      AP +QP+    P    + ++ +P L      +P  P 
Sbjct: 1107 SPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPM 1166

Query: 265  HPSPHPPLQPLTGS----AGQPSAPSHAQPP 291
               P        GS      +P AP    PP
Sbjct: 1167 EVYPECKQTAGQGSPCEEQEEPRAPVAPTPP 1197



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 42/150 (28%)

Query: 129  GEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 188
            G  + ++   +  E  S+P+    +  +TSP +PSP  + S    S          PAL 
Sbjct: 1063 GVSDEAELHEMETEKVSEPECPALEPSATSP-LPSPMGDLSCPAPSPA--------PALD 1113

Query: 189  APTGV----TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP------------------- 225
              +G+     P      PG+   P PG TP + A   +GSP                   
Sbjct: 1114 DFSGLGEDTAPLDGIDAPGSQ--PEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPE 1171

Query: 226  ---TASQAP-----NQPQAPTAPVPHTHIQ 247
               TA Q        +P+AP AP P T I+
Sbjct: 1172 CKQTAGQGSPCEEQEEPRAPVAPTPPTLIK 1201



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 8/116 (6%)

Query: 247  QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 306
            QQ P +   +   P P         L P +   G        QPP   QG  GP  + A 
Sbjct: 3758 QQGPGVQTNQALGPKPQG-------LMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQV-AV 3809

Query: 307  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
               QHPG   P G   Q    Q+ + +SP  A     L      +A Q QQ  + Q
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQ 3865


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score =  115 bits (289), Expect = 2e-25
 Identities = 124/500 (24%), Positives = 179/500 (35%), Gaps = 58/500 (11%)

Query: 22  RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 81
           R +GS+   + GRK      DG+  P        G + P  A  ++N    E VKK+ ++
Sbjct: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221

Query: 82  VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 140
           ++      +++ + Q +       E  R +   +     I RP   SE    ++ +    
Sbjct: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281

Query: 141 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 200
             G+     I  D +   P  P    +++  D    ++ L       +AP   +   +S 
Sbjct: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334

Query: 201 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
           P  TP    P P   A   PP    S T S+ P     P+   P+        +H   P 
Sbjct: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388

Query: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 318
            P   PH  PHP      G  G P   +   PP     PP P      P+ Q P PP   
Sbjct: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442

Query: 319 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 377
           G PP     G  P+G+     +    +  P     +         P PP P   P   PP
Sbjct: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP--------PPPPPPSGQP--PPP 492

Query: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437
           P+ P+P     Q    PP    P P S  A+  P P  +  ++ +T     + PP  Q  
Sbjct: 493 PSGPLPPWQQQQQQPPPP----PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ-- 546

Query: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT--GLHQVAPQPPFAQHPFVPGGPPPITP 495
            Q     +SP  P        +P PP   PP   G     P PP      +   PPP  P
Sbjct: 547 -QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605

Query: 496 PTCPSTSTPPAGPGTSAQPP 515
           P  PS      G G +  PP
Sbjct: 606 PMDPSNFVTMMGMGVAGMPP 625



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 58/193 (30%), Positives = 70/193 (36%), Gaps = 38/193 (19%)

Query: 162 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 215
           P P D    S    S   ++ Q +      P G+ P P   P G P  P  GP P     
Sbjct: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503

Query: 216 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 256
               PP   P++S A + P             A T  +P    QQA A      PQ    
Sbjct: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563

Query: 257 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 309
                 PP   PP P  +P PP  P  GSAG   AP    PP     P  P +      +
Sbjct: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP-----PMDPSNFVTMMGM 618

Query: 310 QHPGPPQPFGLPP 322
              G P PFG+PP
Sbjct: 619 GVAGMP-PFGMPP 630



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 45/163 (27%), Positives = 52/163 (31%), Gaps = 30/163 (18%)

Query: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV----TPAP-------SSAPPGTPQL 207
           P  PS Q     S      Q  Q QPP    P+      TP P       ++   GT  +
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541

Query: 208 PTPGPTPSATAVPP-----QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP---- 258
           P      +A A  P     QG+PT    P   Q P  P        AP   P  PP    
Sbjct: 542 PPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP-------GAPPPPPPPPPGSAG 594

Query: 259 ---SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
              +P PPP P   P         G    P    PP     PP
Sbjct: 595 MMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  115 bits (288), Expect = 2e-25
 Identities = 115/398 (28%), Positives = 151/398 (37%), Gaps = 74/398 (18%)

Query: 187  LQAPTGVTPAPSSAPPGTPQLP---TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 243
            +  P+  T  PS  P  T  LP   TP P  + T  PP   PT + +P      T P   
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP---PTTTPSPPITTTTTPP--- 1449

Query: 244  THIQQAPALHPQRPPSPH--PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH 301
                  P   P  P S    PPP  +P PP           + PS   PP     PP   
Sbjct: 1450 ------PTTTPSPPISTTTTPPPTTTPSPPT----------TTPS---PPTTTPSPPTTT 1490

Query: 302  SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 361
            +    P    P PP    + P AS    P  T+P+     T+   P +     +  PP  
Sbjct: 1491 TTTPPPTTT-PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTT-----TPSPPTT 1544

Query: 362  QPLPPAPLAMPHIKPPPTTPIPQ-----LPAPQAHKHPPHLSGPSPFSMNANLPPPPAL- 415
             P+ P P +   + PP TTP P       P P     PP  + PSP ++    PPP    
Sbjct: 1545 TPITP-PTSTTTL-PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602

Query: 416  KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--PPTGLHQ 473
             P ++ +T  PP+  P P    P + P  S+   PP  T S   PPP  +   PPT    
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPT-STTTLPPTTTPS---PPPTTTTTPPPT---- 1654

Query: 474  VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 533
              P PP    P      PPIT  T P  +T P+ P T+   P +    +       SS P
Sbjct: 1655 TTPSPPTTTTP-----SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS-P 1708

Query: 534  LPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571
            + T               + P    +PSP PT + TPS
Sbjct: 1709 ITTT--------------TTPSSTTTPSPPPTTMTTPS 1732



 Score =  113 bits (283), Expect = 8e-25
 Identities = 109/395 (27%), Positives = 140/395 (35%), Gaps = 56/395 (14%)

Query: 190  PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP---QGSPTASQAPNQPQAPTAPVPHTHI 246
            PT  T  P +  P  P   T  P P+ T  PP     +P  +  P+ P + T   P T  
Sbjct: 1410 PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTT 1469

Query: 247  QQAPALHPQRP---PSPH------PPPHPSPHPPLQ-PLTGSAGQPSAPSHAQPPLHGQG 296
               P   P  P   PSP       PPP  +P PP   P+T     P A +   PP     
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT-----PPASTTTLPPTTTPS 1524

Query: 297  PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
            PP   +    P    P PP    + P  S    P  T+P+   P T+   P         
Sbjct: 1525 PPTTTTTTPPPTTT-PSPPTTTPITPPTSTTTLPPTTTPSP--PPTTTTTP--------- 1572

Query: 357  QPPREQPLPPA------PLAMPHIKPPPTTPIPQL-----PAPQAHKHPPHLSGPSPFSM 405
             PP   P PP       P       PP TTP P       P P     PP  +  +P + 
Sbjct: 1573 -PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631

Query: 406  NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465
               LPP     P  + +T  PP+  P P      S P+ ++   PP  T S  +   P+ 
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS- 1690

Query: 466  HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGS 525
             PPT      P P             PIT  T PS++T P+ P T+   P      S  +
Sbjct: 1691 -PPT-TTMTTPSPTTTP-------SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741

Query: 526  IAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSP 560
                +  P  T       L     P S  PP  SP
Sbjct: 1742 TTMTTLPPTTT----SSPLTTTPLPPSITPPTFSP 1772



 Score =  111 bits (277), Expect = 4e-24
 Identities = 96/348 (27%), Positives = 124/348 (35%), Gaps = 37/348 (10%)

Query: 184  PPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVP 242
            PP    P+      ++ PP T P  PT  P+P  T   P  + T +  P    +P    P
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 243  HTHIQQAPALHPQRPPSP------HPPPHPSPHP----PLQPLTGSAGQPSAPSHAQPPL 292
             T       L P   PSP       PPP  +P P    P+ P T +   P   + + PP 
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 293  HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA 352
                PP P +  + P    P PP      P  +   +P  T+     P T+   P+  + 
Sbjct: 1568 TTTTPP-PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT---PSPPTT 1623

Query: 353  LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP 412
                 P     LPP         PPPTT     P P     PP  + PSP  +     PP
Sbjct: 1624 TPITPPTSTTTLPPTTTP----SPPPTT--TTTPPPTTTPSPPTTTTPSP-PITTTTTPP 1676

Query: 413  PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH 472
            P   P S ++T   P   P      P     PSSP        S   P PP +   T   
Sbjct: 1677 PTTTPSSPITTTPSP---PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733

Query: 473  QVAPQPPFAQHPFVPGG-----------PPPITPPT-CPSTSTPPAGP 508
               P PP      +P             PP ITPPT  P ++T P  P
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score =  110 bits (275), Expect = 7e-24
 Identities = 92/338 (27%), Positives = 119/338 (35%), Gaps = 26/338 (7%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 243
            P    +P   TP+P +  P  P   T  P P+ T  PP  +P        P A T  +P 
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT------PPASTTTLPP 1519

Query: 244  THIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 303
            T     P      PP P   P P    P+ P T +   P   + + PP     PP P + 
Sbjct: 1520 TTTPSPPTTTTTTPP-PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP-PTTT 1577

Query: 304  QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 363
             + P    P PP      P  +   +P  T+     P T+   P+  +      P     
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT---PSPPTTTPITPPTSTTT 1634

Query: 364  LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 423
            LPP         PPPTT     P P     PP  + PSP  +     PPP   P S ++T
Sbjct: 1635 LPPTTTP----SPPPTTTTT--PPPTTTPSPPTTTTPSP-PITTTTTPPPTTTPSSPITT 1687

Query: 424  HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 483
               P   P      P     PSSP        S   P PP +   T      P PP    
Sbjct: 1688 TPSP---PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744

Query: 484  PFVPG---GPPPITPPTCPSTSTPPAGPGTSAQP--PC 516
              +P      P  T P  PS + P   P ++  P  PC
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPC 1782



 Score =  107 bits (267), Expect = 6e-23
 Identities = 104/387 (26%), Positives = 141/387 (36%), Gaps = 60/387 (15%)

Query: 207  LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 266
            + TP P P+ T  PP  S T       P  PT                    +  PPP  
Sbjct: 1396 ITTPSP-PTTTPSPPPTSTTTLPPTTTPSPPTTT------------------TTTPPPTT 1436

Query: 267  SPHPPL-----QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 321
            +P PP+      P T +   P + +   PP      P P +    P    P PP      
Sbjct: 1437 TPSPPITTTTTPPPTTTPSPPISTTTTPPP---TTTPSPPTTTPSPPTTTPSPPTTTTTT 1493

Query: 322  PQASQGQAPLGTSPAAAYPHTS----LQLPASQSALQSQQPPREQPLPP--APLAMP--- 372
            P  +   +P  T+P      T+       P+  +   +  PP   P PP   P+  P   
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553

Query: 373  HIKPPPTTPIP-----QLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL-KPLSSLSTHHP 426
               PP TTP P       P P     PP  + PSP ++    PPP     P ++ +T  P
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP 1613

Query: 427  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP--PASHPPTGLHQVAPQPPFAQHP 484
            P+  P P    P + P  S+   PP  T S   PPP    + PPT      P PP    P
Sbjct: 1614 PTTTPSPPTTTPITPP-TSTTTLPPTTTPS---PPPTTTTTPPPT----TTPSPPTTTTP 1665

Query: 485  FVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 544
                  PPIT  T P  +T P+ P T+   P +    +       SS P+ T        
Sbjct: 1666 -----SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS-PITTTTTPSSTT 1719

Query: 545  DDAEEPE--SPPPPPRSPSPEPTVVDT 569
              +  P   + P P  +PSP  T + T
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPPTTTMTT 1746



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 82/307 (26%), Positives = 115/307 (37%), Gaps = 40/307 (13%)

Query: 162  PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--APPGT------------PQL 207
            PSP      +  ++   +     P+    T  TP P++  +PP T            P  
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559

Query: 208  PTPGPTPSATAVPP---QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPP 264
             TP P P+ T  PP     SP  +  P+ P   T   P T     P      PP P   P
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP-PTTTP 1618

Query: 265  HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP-QPFGLPPQ 323
             P    P+ P T +   P   + + PP     PP P +  + P    P PP      PP 
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP-PTTTPSPPTTTTPSPPITTTTTPPP 1677

Query: 324  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 383
             +   +P+ T+P+   P T++  P+  +   S   P      P+    P   PPPTT   
Sbjct: 1678 TTTPSSPITTTPSP--PTTTMTTPSPTTTPSS---PITTTTTPSSTTTP--SPPPTT--M 1728

Query: 384  QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 443
              P+P     P       P +    LPP     PL+  +T  PPS  PP     P S   
Sbjct: 1729 TTPSPTTTPSP-------PTTTMTTLPPTTTSSPLT--TTPLPPSITPPTFS--PFSTTT 1777

Query: 444  PSSPAQP 450
            P++P  P
Sbjct: 1778 PTTPCVP 1784



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 101/409 (24%), Positives = 134/409 (32%), Gaps = 77/409 (18%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3966 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4024

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 4025 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 4080

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGPSPFS 404
                   Q P   P+       P   P     P TTPI                 P+P  
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--------TPTPTPTG 4192

Query: 405  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA 464
                 P   +  P++ L+T     ++PPP    PQ+    SSP     LT+S  L     
Sbjct: 4193 TQTGPPTHTSTAPIAELTT-----SNPPPESSTPQTSRSTSSP-----LTESTTL----L 4238

Query: 465  SHPPTGLHQVAPQPPFA-QHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523
            S  P  +   +  PP     P    G   ++PP  PST+T P  PGT  +          
Sbjct: 4239 STLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP--PSTTTSP--PGTPTR---------- 4284

Query: 524  GSIAGGSSCPLP-TVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571
            G+  G SS P P TVQ    +               + +P PT + TPS
Sbjct: 4285 GTTTGSSSAPTPSTVQTTTTS---------------AWTPTPTPLSTPS 4318



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 93/406 (22%), Positives = 120/406 (29%), Gaps = 41/406 (10%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3932

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3988

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGPSPFS 404
                   Q P   P+       P   P     P TTPI           P     P+   
Sbjct: 4049 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4108

Query: 405  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP--PGLTQSQNLPPP 462
            +       P   P  +      P+  P          P P+    P    +T +  + P 
Sbjct: 4109 ITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4164

Query: 463  PASHPPTGLHQVAPQPPFAQHPFVPGGPPPIT---PPTCPSTSTPPAGPGTSAQPPCSGA 519
            P    PTG       P        P   P  T   PPT   TST P    T++ PP    
Sbjct: 4165 PT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT--HTSTAPIAELTTSNPP---P 4216

Query: 520  AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 565
             +S    +  +S PL         L  A E  S  PP    +P  T
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1954

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2010

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2011 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2070

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2186

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2241 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2288



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 1919 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1977

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2033

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2209

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2263

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2264 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2311



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2000

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2056

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2057 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2116

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2232

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2287 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 1965 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2023

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2079

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2080 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2139

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2255

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2310 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2357



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 1988 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2046

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2102

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2162

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2278

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2332

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2333 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2380



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2011 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2069

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2125

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2126 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2185

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2246 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2301

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2355

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2356 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2034 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2092

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2148

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2149 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2324

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2379 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2426



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2057 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2171

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2172 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2231

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2347

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2401

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2402 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2449



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2080 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2138

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2194

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2195 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2370

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2425 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2161

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2217

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2393

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2394 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2448 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2495



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2126 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2184

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2240

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2416

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2470

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2471 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2518



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2149 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2207

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2263

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2264 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2439

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2494 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2541



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2172 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2230

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2286

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2462

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2517 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2564



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2195 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2253

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2309

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2430 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2485

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2539

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2540 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2587



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2276

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2332

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2333 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2508

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2562

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2563 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2299

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2355

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2531

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2586 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2264 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2322

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2378

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2554

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2609 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2656



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2345

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2401

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2577

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2631

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2632 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2368

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2424

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2600

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2654

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2655 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2333 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2391

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2447

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2623

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2677

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2678 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2725



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2470

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2591 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2646

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2700

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2701 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2437

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2493

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2669

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2724 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2771



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2516

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2692

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2746

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2747 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2794



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2483

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2539

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2715

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2770 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2506

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2562

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2683 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2738

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2793 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2840



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2529

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2585

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2706 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2761

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2816 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2863



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2608

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2784

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2839 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2575

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2631

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2807

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2808 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2862 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2909



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2654

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2830

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2884

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2885 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2932



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2621

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2677

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2853

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2907

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2908 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2644

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2700

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2876

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2931 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 2978



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2667

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2723

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2844 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2899

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2953

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2954 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3001



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2690

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2746

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2922

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 2977 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2713

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2769

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2945

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2999

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3000 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2736

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2792

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2913 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2968

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3022

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3023 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3070



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2759

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2815

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 2991

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3046 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3093



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2782

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2838

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3014

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3069 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3116



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2861

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3037

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3091

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3092 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3139



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2828

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2884

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3005 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3060

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3115 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2851

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2907

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3028 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3083

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3138 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3185



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2930

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3051 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3106

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3161 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2897

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2953

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3129

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3184 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2920

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2976

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3152

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3207 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3254



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2943

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 2999

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3120 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3175

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3230 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3277



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2966

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3022

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3143 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3198

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3253 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2989

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3045

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3166 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3221

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3276 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3323



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3012

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3068

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3244

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3299 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3346



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3035

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3091

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3267

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3268 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3322 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3058

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3114

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3290

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3345 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3392



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3137

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3313

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3367

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3368 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3415



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3104

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3160

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3281 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3336

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3391 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3127

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3183

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3359

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3414 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3461



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3150

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3206

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3327 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3382

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3437 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3484



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3229

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3405

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3460 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3196

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3252

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3373 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3428

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3483 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3275

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3396 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3451

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3506 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3553



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3242

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3298

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3474

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3529 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3265

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3321

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3497

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3552 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3599



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3288

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3344

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3465 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3520

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3575 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3622



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3311

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3367

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3543

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3598 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3645



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3334

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3390

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3511 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3566

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3621 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3357

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3413

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3534 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3589

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3644 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3691



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3380

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3436

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3612

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3667 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3714



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3403

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3459

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3580 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3635

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3636 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3690 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3737



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3426

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3482

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3603 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3658

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3713 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3760



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3449

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3505

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3681

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3736 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3472

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3528

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3649 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3704

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3759 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3495

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3551

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3727

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3728 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3782 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3829



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3574

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3695 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3750

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3805 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3852



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3541

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3597

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3717

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3718 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3773

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3774 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3828 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3875



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3564

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3620

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3741 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3796

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3851 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3898



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3587

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3643

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3819

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3820 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3874 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3921



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3610

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3611 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3666

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3842

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3897 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3944



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3689

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3809

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3810 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3865

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3919

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3920 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3967



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3656

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3712

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3772

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3833 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3888

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3889 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3942

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3943 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 3990



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3679

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3735

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3911

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3912 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3965

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3966 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4013



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3702

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3758

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3934

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3988

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 3989 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4036



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3725

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3781

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3841

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3902 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3957

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3958 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 4012 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4059



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3748

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3804

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3864

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 3980

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4034

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 4035 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4082



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3771

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3827

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3887

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3888 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3947

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3948 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 4003

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 4058 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4105



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3794

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3850

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3971 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 4026

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4080

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 4081 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4128



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3817

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3873

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3934 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 4049

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 4050 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4103

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 4104 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4151



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 91/420 (21%), Positives = 129/420 (30%), Gaps = 59/420 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3896

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3957 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 4072

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDTPS 571
            P +    +  ++   +  P PT           + P + P       +P+P PT   TP+
Sbjct: 4127 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 93/425 (21%), Positives = 131/425 (30%), Gaps = 61/425 (14%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3863

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
            P P     Q P   P       +P P P  +  P   P+T +      P+    P   Q 
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 3919

Query: 297  PPGPHSLQAGPLLQHPGP-------PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
            P          +   P P         P       +    P GT      P T+      
Sbjct: 3920 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3979

Query: 350  QSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPAPQAHKHPPHLSGP--SP 402
                   Q P   P+       P   P     P TTPI           P     P  +P
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039

Query: 403  FSMNANLPP--------PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
             +    + P         P   P+++ +T  P     P     P + P+ ++    P  T
Sbjct: 4040 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP--T 4095

Query: 455  QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
             +      P + P T    V P P         G   P T P   +T+  P    T  Q 
Sbjct: 4096 PTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQT 4149

Query: 515  PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---PPPRSPSPEPTVVDT-- 569
            P +    +  ++   +  P PT           + P + P       +P+P PT   T  
Sbjct: 4150 PTTTPITTTTTV---TPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTGP 4197

Query: 570  PSHAS 574
            P+H S
Sbjct: 4198 PTHTS 4202



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 63/267 (23%), Positives = 84/267 (31%), Gaps = 27/267 (10%)

Query: 184  PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----A 239
            P      T  T  P+  P GT Q PT  P  + T V P  +PT +Q P      T     
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4139

Query: 240  PVPHTHIQQAPALHP---QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP----SHAQPPL 292
            P P     Q P   P       +P P P  +  P   P+T +      P    +   PP 
Sbjct: 4140 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT 4199

Query: 293  HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA 352
            H    P      + P             PP++S  Q    TS       T L        
Sbjct: 4200 HTSTAPIAELTTSNP-------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 4246

Query: 353  LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP- 411
            + S  PP     P        + PPP+T       P         S P+P ++       
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 4306

Query: 412  -PPALKPLSSLSTHHPPSAHPPPLQLM 437
              P   PLS+ S        P P  ++
Sbjct: 4307 WTPTPTPLSTPSIIRTTGLRPYPSSVL 4333



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 101/504 (20%), Positives = 164/504 (32%), Gaps = 80/504 (15%)

Query: 110  TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNES 169
            T+     T  I+ P S +     ++ S       +  P        +T+PS P       
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP 1675

Query: 170  DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP---QGSPT 226
               ++    +     P     T  TP+P++ P  +P   T  P+ + T  PP     +P+
Sbjct: 1676 PPTTTPSSPITTTPSPPTTTMT--TPSPTTTP-SSPITTTTTPSSTTTPSPPPTTMTTPS 1732

Query: 227  ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH-----PSPHPPLQPLTGSAG- 280
             +  P+ P      +P T    +P      PPS  PP        +P  P  PL    G 
Sbjct: 1733 PTTTPSPPTTTMTTLPPT-TTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGW 1791

Query: 281  -QPSAPSHAQP----PLHGQ--GPPGPHSLQAGPLLQHPGPPQPFGLPPQA--------- 324
                 P+  +P     L G   GP    ++     +    P  P G   Q          
Sbjct: 1792 LDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMY---PDVPIGQLGQTVVCDVSVGL 1848

Query: 325  ---SQGQAPLGTSPAAAYPHTSLQLPASQSALQ---SQQPPREQPLPPAPLAMPHIKPPP 378
               ++ Q P G  P A   +  + +   +   Q         E P PP    +       
Sbjct: 1849 ICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPI-----TT 1903

Query: 379  TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP--------PPALKPLSSLSTHHPPSAH 430
            TT +   P P   + P      +P +    + P         P   P+++ +T  P    
Sbjct: 1904 TTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 1958

Query: 431  PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490
             P     P + P+ ++    P  T +      P + P T    V P P         G  
Sbjct: 1959 -PTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQ 2009

Query: 491  PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550
             P T P   +T+  P    T  Q P +    +  ++   +  P PT           + P
Sbjct: 2010 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPT---------GTQTP 2057

Query: 551  ESPP---PPPRSPSPEPTVVDTPS 571
             + P       +P+P PT   TP+
Sbjct: 2058 TTTPITTTTTVTPTPTPTGTQTPT 2081



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 79/340 (23%), Positives = 108/340 (31%), Gaps = 43/340 (12%)

Query: 143  GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV-TPAPSSAP 201
            G+  P        +T    P+P   ++ + +           P    PTG  TP  +   
Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPIT 4156

Query: 202  PGTPQLPTPGPT--PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPS 259
              T   PTP PT   + T  P   + T +  P      T P  HT       L    PP 
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216

Query: 260  PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG-----P 314
                P  S      PLT S    S      PP        P S    P     G     P
Sbjct: 4217 ESSTPQTS-RSTSSPLTESTTLLS----TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP 4271

Query: 315  PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL-PPAPLAMPH 373
            P     PP         G+S +A  P T       Q+   S   P   PL  P+ +    
Sbjct: 4272 PSTTTSPPGTPTRGTTTGSS-SAPTPST------VQTTTTSAWTPTPTPLSTPSIIRTTG 4324

Query: 374  IKPPPTTPIPQLPAPQAHKHPPH-----LSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
            ++P P++ +        +  P         G + + +N +L         S  ST   PS
Sbjct: 4325 LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST---PS 4381

Query: 429  AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468
              P P     +S P PS P+  P         P P + PP
Sbjct: 4382 PTPTP----SKSTPTPSKPSSTPS-------KPTPGTKPP 4410


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  112 bits (281), Expect = 1e-24
 Identities = 114/363 (31%), Positives = 133/363 (36%), Gaps = 66/363 (18%)

Query: 173 SSAQ---QQMLQAQPPALQA--PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 227
           SSAQ   + + Q + P+L A  P G +P   + P G P  P PG        PPQG    
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP--PPPGKPQGP---PPQGG-NK 67

Query: 228 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH 287
            Q P  P  P  P P     ++P   P +P  P P     P  P  P     G+P  P  
Sbjct: 68  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP----PGKPQGP-- 121

Query: 288 AQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347
             PP  G  P GP           P P +P G PPQ  + ++P         P    Q P
Sbjct: 122 --PPQGGNRPQGP-----------PPPGKPQGPPPQGDKSRSPRS-------PPGKPQGP 161

Query: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKH------PPHLSG 399
             Q   Q Q PP     P  P      KP  PP    PQ P PQ  K       P    G
Sbjct: 162 PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQG 221

Query: 400 PSPFSMNANL-PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP----GLT 454
           P P   N    PPPP  KP             PP     PQ  P P  P  PP      +
Sbjct: 222 PPPQGGNQPQGPPPPPGKP----------QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKS 271

Query: 455 QSQNLPPPPASHPP--TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSA 512
           QS   PP     PP   G +   P PP   +P  P  PP   P   P    PP G G  +
Sbjct: 272 QSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP---RPPQG-GRPS 327

Query: 513 QPP 515
           +PP
Sbjct: 328 RPP 330



 Score =  107 bits (268), Expect = 4e-23
 Identities = 108/361 (29%), Positives = 123/361 (34%), Gaps = 63/361 (17%)

Query: 148 KDIDQDNRST----SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203
           +D+ Q+   +    +P  PSPQ               Q  PP      G        PPG
Sbjct: 21  EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ-----GGNKPQGPPPPG 75

Query: 204 TPQLPTPGPTPSATAVPPQGSPTA--SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261
            PQ P P    S +   P G P     Q  NQPQ P  P P    Q  P     RP  P 
Sbjct: 76  KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNRPQGPP 133

Query: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 321
           PP  P   PP    + S   P       PP  G  P GP           P P +P G P
Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----------PPPPGKPQGPP 183

Query: 322 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381
           PQ   G+ P G  P           P    +  SQ PP +   PP         PPP   
Sbjct: 184 PQG--GKKPQGPPPPGKPQGPP---PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238

Query: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441
            PQ P PQ    P               PPPP  KP              PP Q   +SQ
Sbjct: 239 KPQGPPPQGGNKPQG-------------PPPPG-KP------------QGPPAQGGSKSQ 272

Query: 442 PLPSSPAQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPFVPGGPP----PITP 495
              S P +P G  Q +   P  PP   PP G +   PQ P A  P  P  PP    P  P
Sbjct: 273 SARSPPGKPQGPPQQEGNNPQGPP---PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329

Query: 496 P 496
           P
Sbjct: 330 P 330



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 96/335 (28%), Positives = 114/335 (34%), Gaps = 67/335 (20%)

Query: 247 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 306
           +++P+L    P  P P     P  P  P     G+P  P    PP  G  P GP      
Sbjct: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPP----PGKPQGP----PPQGGNKPQGP------ 71

Query: 307 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
                P P +P G PPQ  + ++P         P    Q P  Q   Q Q PP     P 
Sbjct: 72  -----PPPGKPQGPPPQGDKSRSPRS-------PPGKPQGPPPQGGNQPQGPPPPPGKPQ 119

Query: 367 APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
            P       PP     PQ P P     P    GP P    +  P  P  KP         
Sbjct: 120 GP-------PPQGGNRPQGPPP-----PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 167

Query: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA---SHPPTGLHQVA-------P 476
               PPP    PQ  P P    +P G       PPPP      PP G    +       P
Sbjct: 168 QPQGPPPPPGKPQGPP-PQGGKKPQG-------PPPPGKPQGPPPQGDKSRSSQSPPGKP 219

Query: 477 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP---CSGAAASGGSIAGGSSCP 533
           Q P  Q    P GPPP  PP  P    P  G      PP     G  A GGS +  +  P
Sbjct: 220 QGPPPQGGNQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277

Query: 534 LPTVQIKEEALDDAEEPESPPPP----PRSPSPEP 564
               Q   +   +   P+ PPPP    P+ P   P
Sbjct: 278 PGKPQGPPQ--QEGNNPQGPPPPAGGNPQQPQAPP 310



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 41/150 (27%), Positives = 50/150 (33%), Gaps = 18/150 (12%)

Query: 122 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181
           +P  P     +S  S+S   +    P       +   P    PQ       +  Q     
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257

Query: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SPTASQAPNQPQAPTAP 240
            +P    A  G     + +PPG PQ P     P      PQG  P A   P QPQAP   
Sbjct: 258 GKPQGPPAQGGSKSQSARSPPGKPQGP-----PQQEGNNPQGPPPPAGGNPQQPQAP--- 309

Query: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHP 270
                    PA  PQ PP P     PS  P
Sbjct: 310 ---------PAGQPQGPPRPPQGGRPSRPP 330


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score =  111 bits (277), Expect = 4e-24
 Identities = 121/423 (28%), Positives = 146/423 (34%), Gaps = 87/423 (20%)

Query: 179 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238
           + QA  P L++          + P  P LP  G + SA    P   P     P+      
Sbjct: 103 LFQAGMPKLRSTANRDNDSGGSRP--PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160

Query: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
            P P  +    P       P   PPP PS   P+Q    + G P  P             
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207

Query: 299 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 358
                  GP    PGP  P   P   ++G A  G S          Q P S S+  S +P
Sbjct: 208 ------GGPRQPSPGPTPP---PFPGNRGTALGGGS--------IRQSPLSSSSPFSNRP 250

Query: 359 PREQPLPPAPLAMPHIKPPPTTP------------IPQLPAPQAHKHPPHLSGPSPFSMN 406
               PLPP P      KPPP  P            +P  P P  +  PP  S P P + +
Sbjct: 251 ----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP--PPPPQNNKPPVPSTPRPSASS 304

Query: 407 ANLPPPPALK-------PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 459
              PPPP          P SS      P      L L   + PLPS     PG  +S  L
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS-----PG--RSGPL 357

Query: 460 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA 519
           PPPP+  P          PP  + P    GP P  PP   + ST  A P T   P  SG 
Sbjct: 358 PPPPSERP----------PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407

Query: 520 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARF 579
                S   G   PLP          D     +PPPPP S S      D+P      +RF
Sbjct: 408 ----DSPRSGPRPPLP---------PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRF 454

Query: 580 YKH 582
           Y H
Sbjct: 455 YFH 457



 Score =  102 bits (255), Expect = 1e-21
 Identities = 124/443 (27%), Positives = 159/443 (35%), Gaps = 105/443 (23%)

Query: 140 NDEGSSDPKDIDQDNRSTS------PS------IPSPQDNESDSDSSAQQQM-----LQA 182
           ND G S P  +    RSTS      PS      +PSP       +    +       + +
Sbjct: 119 NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGS 178

Query: 183 QPPALQAPTGVTPAP-SSAP--------PGTPQLPTPGPTP------SATAV---PPQGS 224
           +P ++  P   TP P  S+P        PG P+ P+PGPTP        TA+     + S
Sbjct: 179 KPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238

Query: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284
           P +S +P   + P  P P   +   P   P  P    P  H    PP  P      +P  
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPP-PPPPPVGNRPSIHREAVPPPPP---QNNKPPV 294

Query: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 344
           PS  +P    Q PP P      P    PGPP    LPP +S      G       P  +L
Sbjct: 295 PSTPRPSASSQAPPPP------PPPSRPGPPP---LPPSSS------GNDETPRLPQRNL 339

Query: 345 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 404
            L +S   L S  P R  PLPP P   P   PPP             + PP  SGP    
Sbjct: 340 SLSSSTPPLPS--PGRSGPLPPPPSERP---PPPV------------RDPPGRSGP---- 378

Query: 405 MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQPPGLTQSQNLPPP 462
               LPPPP +    S S   P +   P    +  P+S P P  P   P    S   PPP
Sbjct: 379 ----LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP----SAGAPPP 430

Query: 463 PASHPPTGLHQVAPQPP--------FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
           P   P T +       P        F  HP          PP  P   T  + P   A+ 
Sbjct: 431 PP--PSTSIRNGFQDSPCEDEWESRFYFHPISD------LPPPEPYVQTTKSYPSKLAR- 481

Query: 515 PCSGAAASGGSIAGGSSCPLPTV 537
                + SG +     + PLP +
Sbjct: 482 ---NESRSGSNRRERGAPPLPPI 501



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 94/325 (28%), Positives = 114/325 (35%), Gaps = 58/325 (17%)

Query: 157 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS- 215
           T P  P  +       S  Q  +  + P + + P   TP+ +      P  P  G  PS 
Sbjct: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277

Query: 216 -ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
              AVPP            PQ    PVP T     P+   Q PP P PP  P P PPL P
Sbjct: 278 HREAVPPP----------PPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGP-PPLPP 323

Query: 275 LTGSAGQPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPG--PPQPFGLPPQASQGQAP 330
              S+G    P   Q    L    PP P   ++GPL   P   PP P   PP  S    P
Sbjct: 324 --SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381

Query: 331 LGTSPAAAYPHTSLQLPA-----SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 385
               P +    TS  LPA     S+S + S   PR  P PP P   P    PP       
Sbjct: 382 --PPPVSRNGSTSRALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPP------- 429

Query: 386 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 445
                   PP    P   S+       P      S    HP S  PPP   +  ++  PS
Sbjct: 430 --------PP----PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477

Query: 446 SPAQPPGLTQSQN-------LPPPP 463
             A+    + S         LPP P
Sbjct: 478 KLARNESRSGSNRRERGAPPLPPIP 502


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score =  111 bits (277), Expect = 4e-24
 Identities = 121/423 (28%), Positives = 146/423 (34%), Gaps = 87/423 (20%)

Query: 179 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238
           + QA  P L++          + P  P LP  G + SA    P   P     P+      
Sbjct: 103 LFQAGMPKLRSTANRDNDSGGSRP--PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160

Query: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
            P P  +    P       P   PPP PS   P+Q    + G P  P             
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207

Query: 299 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 358
                  GP    PGP  P   P   ++G A  G S          Q P S S+  S +P
Sbjct: 208 ------GGPRQPSPGPTPP---PFPGNRGTALGGGS--------IRQSPLSSSSPFSNRP 250

Query: 359 PREQPLPPAPLAMPHIKPPPTTP------------IPQLPAPQAHKHPPHLSGPSPFSMN 406
               PLPP P      KPPP  P            +P  P P  +  PP  S P P + +
Sbjct: 251 ----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP--PPPPQNNKPPVPSTPRPSASS 304

Query: 407 ANLPPPPALK-------PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 459
              PPPP          P SS      P      L L   + PLPS     PG  +S  L
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS-----PG--RSGPL 357

Query: 460 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA 519
           PPPP+  P          PP  + P    GP P  PP   + ST  A P T   P  SG 
Sbjct: 358 PPPPSERP----------PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407

Query: 520 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARF 579
                S   G   PLP          D     +PPPPP S S      D+P      +RF
Sbjct: 408 ----DSPRSGPRPPLP---------PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRF 454

Query: 580 YKH 582
           Y H
Sbjct: 455 YFH 457



 Score =  102 bits (255), Expect = 1e-21
 Identities = 124/443 (27%), Positives = 159/443 (35%), Gaps = 105/443 (23%)

Query: 140 NDEGSSDPKDIDQDNRSTS------PS------IPSPQDNESDSDSSAQQQM-----LQA 182
           ND G S P  +    RSTS      PS      +PSP       +    +       + +
Sbjct: 119 NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGS 178

Query: 183 QPPALQAPTGVTPAP-SSAP--------PGTPQLPTPGPTP------SATAV---PPQGS 224
           +P ++  P   TP P  S+P        PG P+ P+PGPTP        TA+     + S
Sbjct: 179 KPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238

Query: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284
           P +S +P   + P  P P   +   P   P  P    P  H    PP  P      +P  
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPP-PPPPPVGNRPSIHREAVPPPPP---QNNKPPV 294

Query: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 344
           PS  +P    Q PP P      P    PGPP    LPP +S      G       P  +L
Sbjct: 295 PSTPRPSASSQAPPPP------PPPSRPGPPP---LPPSSS------GNDETPRLPQRNL 339

Query: 345 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 404
            L +S   L S  P R  PLPP P   P   PPP             + PP  SGP    
Sbjct: 340 SLSSSTPPLPS--PGRSGPLPPPPSERP---PPPV------------RDPPGRSGP---- 378

Query: 405 MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQPPGLTQSQNLPPP 462
               LPPPP +    S S   P +   P    +  P+S P P  P   P    S   PPP
Sbjct: 379 ----LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP----SAGAPPP 430

Query: 463 PASHPPTGLHQVAPQPP--------FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
           P   P T +       P        F  HP          PP  P   T  + P   A+ 
Sbjct: 431 PP--PSTSIRNGFQDSPCEDEWESRFYFHPISD------LPPPEPYVQTTKSYPSKLAR- 481

Query: 515 PCSGAAASGGSIAGGSSCPLPTV 537
                + SG +     + PLP +
Sbjct: 482 ---NESRSGSNRRERGAPPLPPI 501



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 94/325 (28%), Positives = 114/325 (35%), Gaps = 58/325 (17%)

Query: 157 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS- 215
           T P  P  +       S  Q  +  + P + + P   TP+ +      P  P  G  PS 
Sbjct: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277

Query: 216 -ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
              AVPP            PQ    PVP T     P+   Q PP P PP  P P PPL P
Sbjct: 278 HREAVPPP----------PPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGP-PPLPP 323

Query: 275 LTGSAGQPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPG--PPQPFGLPPQASQGQAP 330
              S+G    P   Q    L    PP P   ++GPL   P   PP P   PP  S    P
Sbjct: 324 --SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381

Query: 331 LGTSPAAAYPHTSLQLPA-----SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 385
               P +    TS  LPA     S+S + S   PR  P PP P   P    PP       
Sbjct: 382 --PPPVSRNGSTSRALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPP------- 429

Query: 386 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 445
                   PP    P   S+       P      S    HP S  PPP   +  ++  PS
Sbjct: 430 --------PP----PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477

Query: 446 SPAQPPGLTQSQN-------LPPPP 463
             A+    + S         LPP P
Sbjct: 478 KLARNESRSGSNRRERGAPPLPPIP 502


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score =  111 bits (277), Expect = 4e-24
 Identities = 108/371 (29%), Positives = 141/371 (38%), Gaps = 77/371 (20%)

Query: 170 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----P 225
           D  S  +QQM    P  LQ P  + P P       PQ+    P+ S+    PQ      P
Sbjct: 256 DLYSQGKQQMPHHTPHQLQQPPSLQPTPQ-----VPQVQQSQPSQSSEPSQPQQKDPQQP 310

Query: 226 TASQAPNQPQAPTAPVPHT--HIQQAPALHPQR------PPSPHPPPHPSPHPPLQPLTG 277
              Q P Q     +P P +   +++A  + P+       PP P  P   + HPPL P   
Sbjct: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA-- 368

Query: 278 SAGQPSAPSHAQPPLHGQ----GPPGPHSLQAGPLLQHPGP--PQPFGLPPQASQGQAPL 331
                  P   +PPL        PPGP      P +Q P P  P P   PP       P 
Sbjct: 369 -----HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP- 422

Query: 332 GTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 391
              P ++Y  T +   +S  + +  Q  +         +M   + P    +P    P AH
Sbjct: 423 --PPPSSYM-TGMSTTSSYMSGEGYQSLQ---------SMMKTEGPSYGALPPAYGPPAH 470

Query: 392 -KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 450
             + PH+  P+P       PPPP   P +S     PP A PPP          P  P  P
Sbjct: 471 LPYHPHVYPPNP-------PPPPVPPPPASF----PPPAIPPPT---------PGYPPPP 510

Query: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPP---------FAQHPFVPGGPPPITPPTCPST 501
           P  T + N PPPP   PPT  H V P PP         +      PGG PP+ PP  P  
Sbjct: 511 P--TYNPNFPPPPPRLPPT--HAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566

Query: 502 STPPAGPGTSA 512
             P  G G +A
Sbjct: 567 MPPVGGLGRAA 577



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 103/354 (29%), Positives = 126/354 (35%), Gaps = 71/354 (20%)

Query: 123 PNSPSEGEGESSDSRSVNDEGSSDPKD-IDQDNRSTSPSIPSPQDNESDSDSSA-----Q 176
           P  P   + + S S   +     DP+    Q   +  P  PSPQ +       A     +
Sbjct: 283 PQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPK 342

Query: 177 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236
           ++   A+PP  + P   T  P   PP  P  P     P A A+     P    A + P+ 
Sbjct: 343 EENKAAEPPPPKIPKIETTHP-PLPPAHP--PPDRKPPLAAALGEAEPPGPVDATDLPKV 399

Query: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
              P  H      PA   Q PP PH PP   P PP   +TG +   S  S          
Sbjct: 400 QIPPPAH------PAPVHQPPPLPHRPP---PPPPSSYMTGMSTTSSYMS---------- 440

Query: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
             G  SLQ+  +++  GP          S G  P    P A  P+     P +       
Sbjct: 441 GEGYQSLQS--MMKTEGP----------SYGALPPAYGPPAHLPYHPHVYPPN------- 481

Query: 357 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 416
            PP   P PPA    P I PPPT   P                P P + N N PPPP   
Sbjct: 482 PPPPPVPPPPASFPPPAI-PPPTPGYP----------------PPPPTYNPNFPPPPPRL 524

Query: 417 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 470
           P     TH  P   PP L L P S P    PA PPG       P PP   PP G
Sbjct: 525 P----PTHAVPPHPPPGLGLPPASYP---PPAVPPGGQPPVPPPIPPPGMPPVG 571



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 83/297 (27%), Positives = 97/297 (32%), Gaps = 77/297 (25%)

Query: 300 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359
           PH LQ  P LQ P P  P     Q SQ   P              Q PA Q    S QP 
Sbjct: 270 PHQLQQPPSLQ-PTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPS 328

Query: 360 REQPLPPAPLAMPHIK----PPPTTPIPQL-----PAPQAHKHPPHLSGPSPFSMNANLP 410
             + +  A +  P  +     PP   IP++     P P AH  PP    P   ++    P
Sbjct: 329 SPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP-PPDRKPPLAAALGEAEP 387

Query: 411 PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP------------------G 452
           P P +          PP AHP P+   P   PLP  P  PP                  G
Sbjct: 388 PGP-VDATDLPKVQIPPPAHPAPVHQPP---PLPHRPPPPPPSSYMTGMSTTSSYMSGEG 443

Query: 453 LTQSQNLPP---------PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST 503
               Q++           PPA  PP  L       P+  H + P  PPP  PP   S   
Sbjct: 444 YQSLQSMMKTEGPSYGALPPAYGPPAHL-------PYHPHVYPPNPPPPPVPPPPASFPP 496

Query: 504 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSP 560
           P   P T   PP                 P PT             P  PPPPPR P
Sbjct: 497 PAIPPPTPGYPP-----------------PPPTY-----------NPNFPPPPPRLP 525



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 76/244 (31%), Positives = 95/244 (38%), Gaps = 43/244 (17%)

Query: 340 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 399
           PH   Q P+ Q   Q  Q  + QP   +  + P  K P      Q PA Q  K  P  S 
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329

Query: 400 P---------SPFSMNANLPPPPALKPLSSLSTHHPP--SAHPPPLQLMPQSQPLPSSPA 448
           P         SP   N    PPP   P   + T HPP   AHPPP +  P +  L    A
Sbjct: 330 PRQVKRAVVVSPKEENKAAEPPPPKIP--KIETTHPPLPPAHPPPDRKPPLAAAL--GEA 385

Query: 449 QPPGLTQSQNLPP---PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT----CPST 501
           +PPG   + +LP    PP +HP           P  Q P +P  PPP  P +      +T
Sbjct: 386 EPPGPVDATDLPKVQIPPPAHPA----------PVHQPPPLPHRPPPPPPSSYMTGMSTT 435

Query: 502 STPPAGPG-TSAQPPCSGAAASGGSI--AGGSSCPLPTVQIKEEALDDAEEPESPPPPPR 558
           S+  +G G  S Q        S G++  A G    LP              P +PPPPP 
Sbjct: 436 SSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP--------YHPHVYPPNPPPPPV 487

Query: 559 SPSP 562
            P P
Sbjct: 488 PPPP 491



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 48/179 (26%), Positives = 61/179 (34%), Gaps = 18/179 (10%)

Query: 389 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 448
           Q   H PH            L  PP+L+P   +    P      P Q    SQP    P 
Sbjct: 264 QMPHHTPH-----------QLQQPPSLQPTPQV----PQVQQSQPSQSSEPSQPQQKDPQ 308

Query: 449 QPPGLTQSQNLPPPPASHP--PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 506
           QP    Q    P  P+  P  P  + +     P  ++      PP I          PPA
Sbjct: 309 QPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA 368

Query: 507 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 565
            P    +PP + A           +  LP VQI   A   A   + PP P R P P P+
Sbjct: 369 HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA-HPAPVHQPPPLPHRPPPPPPS 426



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 74/338 (21%), Positives = 118/338 (34%), Gaps = 81/338 (23%)

Query: 630 REKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF--EPPPTTIAA 687
           ++ +  +  E  + ++++ ++ A+    A + +   PQ S P  ++ +    P     AA
Sbjct: 289 QQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAA 348

Query: 688 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 747
            PP   P  P + T +    P    P +R  P    L   +P      PG   VD T   
Sbjct: 349 EPP--PPKIPKIET-THPPLPPAHPPPDRKPPLAAALGEAEP------PG--PVDAT--- 394

Query: 748 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 807
            +L + +I                     PP   P HPA  P+     H    +P    P
Sbjct: 395 -DLPKVQI---------------------PP---PAHPA--PV-----HQPPPLPHRPPP 422

Query: 808 HPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFN 867
            P +S+  G++                  SY   ++ E   + +    T  P        
Sbjct: 423 PPPSSYMTGMSTTS---------------SY---MSGEGYQSLQSMMKTEGP----SYGA 460

Query: 868 VTPHHHQHSHIHSHLHLHQQDP----LHQGSAGPVHPLVDPLTAG------PHLARFPYP 917
           + P +   +H+  H H++  +P    +    A    P + P T G       +   FP P
Sbjct: 461 LPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520

Query: 918 PGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPP 955
           P  LP P    PPH    L  P    P P   PG  PP
Sbjct: 521 PPRLP-PTHAVPPHPPPGLGLPPASYPPPAVPPGGQPP 557


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score =  110 bits (274), Expect = 9e-24
 Identities = 131/416 (31%), Positives = 163/416 (39%), Gaps = 67/416 (16%)

Query: 176 QQQMLQAQPPALQAPTGVTPAPSS-APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234
           Q Q   A P A     GVT  PS+ A   TP       TP+A         T   AP  P
Sbjct: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP 628

Query: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 294
            A + P+P   +QQ  A  P + P+P     P    P QP  G A  P      QPP   
Sbjct: 629 PAVSTPLP-LGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVLGQPP--- 683

Query: 295 QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 354
                P ++     LQ         LP + SQ   PL    +A  PH  L +PAS   + 
Sbjct: 684 --SATPTAILTQDSLQ-------MFLPQERSQ--QPL----SAEGPH--LSVPAS--VIV 724

Query: 355 SQQPPREQPLPPAPLAM--------PHIKPPPTTPIPQLPAPQAHKHPPHLSGPS----- 401
           S  PP + P P  P+A         P  +  P  P PQ+PA    K P   S PS     
Sbjct: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA-PAPQIPAAAPLKGPGPSSSPSLPHQA 783

Query: 402 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--TQSQNL 459
           P   + +LP P   +P  S     P S   PP +      P P +P   PG+   Q+Q  
Sbjct: 784 PLGDSPHLPSPHPTRP-PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842

Query: 460 PPPPASHP-PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ--PPC 516
            PPPAS+P PT     AP PP           PP+ P      S PP GP   A   PP 
Sbjct: 843 VPPPASNPAPT-----APGPP----------QPPLRP-----QSQPPEGPLPPAPHLPPS 882

Query: 517 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP-ESPPPPPR-SPSPEPTVVDTP 570
           S ++A   S    S  P PT    +     ++ P +SP PPP     PEP     P
Sbjct: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938



 Score =  110 bits (274), Expect = 9e-24
 Identities = 138/483 (28%), Positives = 170/483 (35%), Gaps = 105/483 (21%)

Query: 122  RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181
            +P +P+   GE++   +V     + P          + S P P   +      AQQ    
Sbjct: 604  QPATPAAATGEAAPVLTVQPAPQAPP----------AVSTPLPLGLQQPQ---AQQPPQA 650

Query: 182  AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA--TAVPPQGS------PTASQAPNQ 233
              P A   P   TP PS     +P+    G  PSA  TA+  Q S         SQ P  
Sbjct: 651  PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710

Query: 234  PQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 293
             + P   VP + I  A            PPP   P P      G+   P AP     P  
Sbjct: 711  AEGPHLSVPASVIVSA------------PPPAQDPAPATPVAKGAGLGPQAPDSQASP-- 756

Query: 294  GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 353
                P P    A P L+ PGP     LP      QAPLG SP    PH +          
Sbjct: 757  ---APAPQIPAAAP-LKGPGPSSSPSLP-----HQAPLGDSPHLPSPHPT---------- 797

Query: 354  QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 413
               +PP   P  P  ++    +PP   P+   P PQA   PP L G         +PPP 
Sbjct: 798  ---RPPSRPPSRPQSVS----RPPSEPPLHPCPPPQA---PPTLPGIFVIQNQLGVPPP- 846

Query: 414  ALKPLSSLSTHHPPSAHPPPLQLMPQSQ----PLPSSPAQPPGLTQ---------SQNLP 460
                    S   P +  PP   L PQSQ    PLP +P  PP  T          S  LP
Sbjct: 847  -------ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899

Query: 461  PPPASH------PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-PAGPGTSA- 512
             P  S       P  G H+    PP       P  PPP  P T    +TP PA P   A 
Sbjct: 900  APTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL 959

Query: 513  -----QPPCSGA----AASGGSIAGGSSCPL-PTVQIKEEALDDAEEPE-SPPPPPRSPS 561
                 Q P SG      A G   A  +S  L P        L   + P  +P  P  +P+
Sbjct: 960  LERFHQVP-SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPA 1018

Query: 562  PEP 564
            P P
Sbjct: 1019 PAP 1021



 Score =  106 bits (264), Expect = 1e-22
 Identities = 141/540 (26%), Positives = 196/540 (36%), Gaps = 91/540 (16%)

Query: 56   GRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKT 115
            G   P+  + ++ ++      + A +     S+PL    +Q +      ++  +  + + 
Sbjct: 601  GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ-----AQQPPQAPTPQA 655

Query: 116  KTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI-DQDN-RSTSPSIPSPQDNESDSDS 173
                 +    PS G   S +   +    S+ P  I  QD+ +   P   S Q   ++   
Sbjct: 656  AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715

Query: 174  -SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAVPPQGSPTAS 228
             S    ++ + PP  Q P   TP    A  G PQ P    +P P P   A  P   P  S
Sbjct: 716  LSVPASVIVSAPPPAQDPAPATPVAKGAGLG-PQAPDSQASPAPAPQIPAAAPLKGPGPS 774

Query: 229  QAPNQP-QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPSAP 285
             +P+ P QAP    PH      P+ HP RPPS  PP  P     PP +P       P  P
Sbjct: 775  SSPSLPHQAPLGDSPHL-----PSPHPTRPPS-RPPSRPQSVSRPPSEPPL----HPCPP 824

Query: 286  SHAQPPLHG-------QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 338
              A P L G        G P P S    P    PGPPQP    P   Q Q P G  P A 
Sbjct: 825  PQAPPTLPGIFVIQNQLGVPPPAS---NPAPTAPGPPQP----PLRPQSQPPEGPLPPAP 877

Query: 339  Y--PHTSLQLPASQSALQSQQP---PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH 393
            +  P ++    AS S   S+ P   P +  L   P   PH  P P   +  +P P A   
Sbjct: 878  HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA--- 934

Query: 394  PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 453
                            PPPP  +    ++T  P  A P P  L+ +   +PS       +
Sbjct: 935  ----------------PPPPPPRTFQMVTTPFP--ALPQPKALLERFHQVPSGI-----I 971

Query: 454  TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 513
             Q++    P A    T L    P    A    V G  P  TP T PS +  PA    +  
Sbjct: 972  LQNKAGGAPAAPQTSTSL---GPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGL 1027

Query: 514  PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPES----------PPPPPRSPSPE 563
            PP     A   + A      LPT+ + + A     +P              PP   PS E
Sbjct: 1028 PPL--LPAENKAFASN----LPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 123/440 (27%), Positives = 152/440 (34%), Gaps = 76/440 (17%)

Query: 192 GVTPAPSSAPPGTPQLPTPG-------PTPSA----TAVPPQGSPTASQAPNQPQ---AP 237
           G   AP+  P G P    PG       P P+     T  P Q  P     P   Q    P
Sbjct: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP 370

Query: 238 TAPVPHT-HIQQAPALHPQRPPSPH-------------------PPPHPSPHPPLQP--L 275
            AP   T  IQ  P   PQ+P +P                    P P    +   QP   
Sbjct: 371 FAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPAT 430

Query: 276 TGSAGQPSAPSHAQPP----LHGQGP----PGPHSLQAGPLLQHPGPPQPFGLPPQASQG 327
           T  A  P  P     P    L  QG     P  H L        PG P    LP Q S  
Sbjct: 431 TTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAP-AVQLPQQLSAL 489

Query: 328 QAPLGTS-PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP-----PTTP 381
            A +G    AAA PHT  QL A+   L +Q      PL   P+  PH            P
Sbjct: 490 PANVGGQILAAAAPHTGGQLIAN-PILTNQN--LAGPLSLGPVLAPHSGAHSAHILSAAP 546

Query: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA----HPPPLQLM 437
           I Q+  P   + P  L+  S  + +   P  PA   +    T  PPSA    + P   + 
Sbjct: 547 I-QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT-LPPSAVAMLNTPDGLVQ 604

Query: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQ-VAPQPPFAQHPFVPGGPPPITP 495
           P +    +  A P    Q     PP  S P P GL Q  A QPP A  P     P   TP
Sbjct: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664

Query: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE---- 551
              P  ++ P       QPP    +A+  +I    S  +   Q + +    AE P     
Sbjct: 665 QPSPGLASSPE-KIVLGQPP----SATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719

Query: 552 -----SPPPPPRSPSPEPTV 566
                S PPP + P+P   V
Sbjct: 720 ASVIVSAPPPAQDPAPATPV 739



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 105/459 (22%), Positives = 150/459 (32%), Gaps = 67/459 (14%)

Query: 88   SPLKSNKRQREKVASDTEEADRTSSKKTKTQ----EISRPNSPSEGEGESSDSRSVNDEG 143
            SP   +K   E     T+   RT +   K +    E SR  SPS  E    D   + +E 
Sbjct: 1126 SPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPS-AEMVMIDRMFIQEEK 1184

Query: 144  SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203
            ++   D           + S +       +S++   L    P   +     P  S+ PP 
Sbjct: 1185 TTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSS----APGASTQPP- 1239

Query: 204  TPQLPTP--------GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 255
             P LPT         G +PS T      S ++S + +     +A       +  P     
Sbjct: 1240 -PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSS-----SAASSLDADEDGPMPSRN 1293

Query: 256  RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ-AGPLLQHPGP 314
            RPP             L+    +       + A  P+H Q PP P +L+ A P  + P P
Sbjct: 1294 RPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVH-QPPPPPATLKVAEPPPRPPPP 1352

Query: 315  PQPFGL-------PPQASQGQAPLGTSPAAA---YPHTSLQLPASQSALQSQQPPREQPL 364
            P P G        PP A+  + PLGT+P         T  +      A +     R +  
Sbjct: 1353 PPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGG 1412

Query: 365  PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 424
             PAPL    +    +  I +L A +   +   L GP         PP PA          
Sbjct: 1413 SPAPLPAK-VDEATSGLIRELAAVEDELYQRMLKGP---------PPEPAASAAQGTGDP 1462

Query: 425  HPPSAHPPPLQLMPQSQP------LPSSPAQPPGLTQSQ--------NLPPPPASHPPTG 470
               +   PP +      P        S   Q   LT+          NL   P   P   
Sbjct: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP--- 1519

Query: 471  LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 509
                AP  P A     P  PPP+  P     S+   G G
Sbjct: 1520 ----APSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLG 1554



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 79/309 (25%), Positives = 97/309 (31%), Gaps = 77/309 (24%)

Query: 278  SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337
            S G P A S     L G GP       + P      PP    LP +        G SP+ 
Sbjct: 1207 SLGLPIAASSEGHRLPGHGPLS----SSAPGASTQPPPH---LPTKLVIRHGGAGGSPSV 1259

Query: 338  AYPHTSLQLPASQS---ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394
             +   S  L +S S   A  S     + P       MP    PP                
Sbjct: 1260 TWARASSSLSSSSSSSSAASSLDADEDGP-------MPSRNRPPIKTYEARSRIGLKLKI 1312

Query: 395  PHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
               +G S    N  L P            H PP   PPP  L           A+PP   
Sbjct: 1313 KQEAGLSKVVHNTALDP-----------VHQPP---PPPATL---------KVAEPP--- 1346

Query: 455  QSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP------STSTPPAG 507
                 P PP   PPTG ++     PP    P  P   P  T P CP      +      G
Sbjct: 1347 -----PRPPPPPPPTGQMNGTVDHPP----PAAPERKPLGTAPHCPRLPLRKTYRENVGG 1397

Query: 508  PGTSAQPPCSGAAASGGSIAGGSSCPLP-------TVQIKEEALDDAE----EPESPPPP 556
            PG     P        G   GGS  PLP       +  I+E A  + E      + PPP 
Sbjct: 1398 PGAPEGTP-------AGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE 1450

Query: 557  PRSPSPEPT 565
            P + + + T
Sbjct: 1451 PAASAAQGT 1459


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score =  108 bits (271), Expect = 2e-23
 Identities = 167/669 (24%), Positives = 227/669 (33%), Gaps = 144/669 (21%)

Query: 10   DGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST---- 65
            D  S   S  T  S GS  + + G + QP S     S +      SGR SPS  ST    
Sbjct: 414  DTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEAS 473

Query: 66   ------SSNDSKAETVKKSAKKVKEEASSPLKSNK-RQREKVASDTEEADRTSSKKTKTQ 118
                  SS      +V  S +K+K     P +++   QR     D         ++ +  
Sbjct: 474  DTLSIRSSGQLSGRSV--SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQP 531

Query: 119  EISRPN-----------------------------------------SPSEGEGESSDSR 137
            ++ RP                                          SPS G    S + 
Sbjct: 532  QLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTP 591

Query: 138  SVNDEGSSDPK---------------DIDQDNRSTSPSIPSPQDNESD---SDSSAQQQM 179
            ++  +G + P                 +     S S S+ S   + SD   SD S  Q +
Sbjct: 592  TLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651

Query: 180  LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPT 238
                   +  P    PAP S PP  P+ P P  P  +A AV P    T   +P  P  PT
Sbjct: 652  TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP--PT 709

Query: 239  APVPHTHIQQAPALHPQRPPSPHPPP--HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
                 T +Q++P +   + P P PPP  HP P P  +P       PSA   A+ PL    
Sbjct: 710  PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV-VVEAPSASETAEEPLQDPN 768

Query: 297  -----PPGPHSLQAGPLLQHPGPPQPF----GLPPQASQGQAPLGTSPAAAYPHTSLQLP 347
                 PP P   Q   +   P P + F       P    G   L +SPAA+         
Sbjct: 769  WPPPPPPAPEE-QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS--------S 819

Query: 348  ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS---GPSPFS 404
            +S +ALQ Q P    P PPAP A     P P +  P   A    K P   S   GP    
Sbjct: 820  SSATALQIQPPGSPDP-PPAPPA-----PAPASSAPGHVAKLPQKEPVGCSKGGGPPRED 873

Query: 405  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA 464
            + A L  P  L+ +   S   P  A  P L         PS+P +P     S    P PA
Sbjct: 874  VGAPLVTPSLLQMVRLRSVGAPGGAPTPALG--------PSAPQKPLRRALSGRASPVPA 925

Query: 465  SHPPTGLHQVAPQPPFAQ------HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 518
              P +GLH        +           P GPP   P        PP  P ++A    S 
Sbjct: 926  --PSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP-------RPPQSPASTASFIFSK 976

Query: 519  AAA-----------SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 567
             +            +   +       L ++  +       + P++PPP  R PS     V
Sbjct: 977  GSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS-----V 1031

Query: 568  DTPSHASQS 576
              P  AS S
Sbjct: 1032 GVPPPASPS 1040



 Score =  105 bits (263), Expect = 2e-22
 Identities = 182/773 (23%), Positives = 259/773 (33%), Gaps = 148/773 (19%)

Query: 14   GKHSMRTRRS----RGSMSTLRS-GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN 68
            G+ S+RT         S +++RS GR    +SP  R+           R+  S++ T S+
Sbjct: 370  GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRS-----------RHPSSSSDTWSH 418

Query: 69   DSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE 128
               ++T+      +  +  S                E +  ++S     Q  S   SPS 
Sbjct: 419  SQSSDTIVSDGSTLSSKGGSE------------GQPESSTASNSVVPPPQGGSGRGSPSG 466

Query: 129  GE-GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 187
            G   E+SD+ S+   G    + +        P  P P+   S         + Q      
Sbjct: 467  GSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP--PPPRRTHS---------LHQRGLAVP 515

Query: 188  QAPTGVTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI 246
              P G+ P P     P  P+ PT G +  A A P   +P  S  P      +   P +  
Sbjct: 516  DGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRS-- 573

Query: 247  QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP-------LHGQGPPG 299
                   P+R  SP          P  P  G AG P++P  AQPP       L   G   
Sbjct: 574  -------PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626

Query: 300  PHSL--------------QAGPLL-----------QHPGPPQPFGLPPQASQGQAPLGTS 334
              SL              ++GP +            HP  P PF  PP  S+ ++P   +
Sbjct: 627  SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP--SKPRSPNPAA 684

Query: 335  PAAAYPHTSLQLPASQSALQSQQPPREQ----PLPPAPLAMPHIKPPPTTPIPQLPAPQA 390
            PA A P   +  P S +    Q PP  Q    PL  +P+      PPP+ P    P P  
Sbjct: 685  PALAAPAV-VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743

Query: 391  HKHPPHLSGPSPFSMNA-------NLPPPPALKPLSS-LSTHHPPSAHPPPLQLMPQSQP 442
             K P  +      S  A       N PPPP   P    LS    P   PP       + P
Sbjct: 744  TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP---PPEEAFFSVASP 800

Query: 443  LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502
             P+ P+  P L  S     P AS       Q+ P          PG P P  PP  P+ +
Sbjct: 801  EPAGPSGSPELVSS-----PAASSSSATALQIQP----------PGSPDP--PPAPPAPA 843

Query: 503  TPPAGPGTSAQPPCS---GAAASGGSIAGGSSCPLPTVQIKEEA-LDDAEEPESPPPPPR 558
               + PG  A+ P     G +  GG        PL T  + +   L     P   P P  
Sbjct: 844  PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903

Query: 559  SPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK-LAKKREEAIEKAK 617
             PS        P   + S R            A   L    LA S+ L+  +     +A+
Sbjct: 904  GPSAP----QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE 959

Query: 618  REAEQ-----------KAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 666
                Q           K   + + E+    E + + +R   AE  + +     +     P
Sbjct: 960  PRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP 1019

Query: 667  QLSGPGHMRPSFEPPPTTIAAVP---PYIGPDTPALRTLSEYARPHVMSPTNR 716
            +   P   +PS   PP    + P   P   P T  L        PH    T R
Sbjct: 1020 KAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL--------PHTQDRTKR 1064



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 43/172 (25%), Positives = 66/172 (38%), Gaps = 26/172 (15%)

Query: 173  SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTAS-QAP 231
            SS     ++ +  +L A  G++ A  + PP     P   P  +A+ +  +GS     + P
Sbjct: 927  SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986

Query: 232  NQPQ----------APTAPVPHTHIQQAPALHPQRPPSPH-------PPPHPSPHPPLQP 274
              P+          A    +      QAP   P+ PP          PPP    +P  +P
Sbjct: 987  VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP 1046

Query: 275  LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 326
            LT      + P++  P  H Q        + G +LQ  GP +  GLP   SQ
Sbjct: 1047 LT------APPTNGLP--HTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQ 1090


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score =  107 bits (268), Expect = 4e-23
 Identities = 121/497 (24%), Positives = 175/497 (35%), Gaps = 79/497 (15%)

Query: 22  RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 81
           R +GS+   + GRK      DG+  P        G + P  A  ++N    E VKK+ ++
Sbjct: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221

Query: 82  VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 140
           ++      +++ + Q +       E  R +   +     I RP   SE    ++ +    
Sbjct: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281

Query: 141 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 200
             G+     I  D +   P  P    +++  D    ++ L       +AP   +   +S 
Sbjct: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334

Query: 201 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
           P  TP    P P   A   PP    S T S+ P     P+   P+        +H   P 
Sbjct: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388

Query: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 318
            P   PH  PHP      G  G P   +   PP     PP P      P+ Q P PP   
Sbjct: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442

Query: 319 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 377
           G PP     G  P+G+     +    +                   +PP P+ M    PP
Sbjct: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480

Query: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437
           P       P P + + PP  SGP P        PPP   P SS+++  P     P  Q  
Sbjct: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP----LPWQQNT 529

Query: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 497
             +     + + PP   Q       P +    G   + P PP  Q P  PG PPP  PP 
Sbjct: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP- 588

Query: 498 CPSTSTPPAGPGTSAQP 514
                 PP   G    P
Sbjct: 589 ------PPGSAGMMIPP 599



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 95/333 (28%), Positives = 121/333 (36%), Gaps = 61/333 (18%)

Query: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 318
           +P P    S   P      SA +P+AP++  PP     P    + Q+ P   + GP +  
Sbjct: 323 APVPASVGSTSGPATTPLASAPRPAAPANNPPP-----PSLMSTTQSRPPWMNSGPSE-- 375

Query: 319 GLPPQASQGQAPLGTSPAA-AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 377
             P     G  P G      ++PH    L         Q  P     PP P   P   PP
Sbjct: 376 SRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNG---PPPPWMQP---PP 429

Query: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437
           P  P+ Q P      HPP   GP P  M+  L   P    +  L  H      PPP    
Sbjct: 430 P--PMNQGP------HPPGHHGPPP--MDQYLGSTPVGSGVYRL--HQGKGMMPPP---- 473

Query: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP----- 492
               P+   P  PP        PPPP+  PP       P PP+ Q    P  PPP     
Sbjct: 474 ----PMGMMP--PP--------PPPPSGQPPP--PPSGPLPPWQQQQQQPPPPPPPSSSM 517

Query: 493 --ITP-PTCPSTSTPPAGPGTSAQPP-----CSGAAASGGSIAGGSSCPLPTVQIKEEAL 544
              TP P   +T+T     GT + PP      + AA+ G     G+   +P     +  L
Sbjct: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577

Query: 545 DDAEEPESPPPPPRSPSP--EPTVVDTPSHASQ 575
                P  PPPPP S      P   D PSH S+
Sbjct: 578 PPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESE 610



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 54/184 (29%), Positives = 64/184 (34%), Gaps = 38/184 (20%)

Query: 162 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 215
           P P D    S    S   ++ Q +      P G+ P P   P G P  P  GP P     
Sbjct: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503

Query: 216 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 256
               PP   P++S A + P             A T  +P    QQA A      PQ    
Sbjct: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563

Query: 257 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 309
                 PP   PP P  +P PP  P  GSAG         PP  G GP         PL+
Sbjct: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGM------MIPPRGGDGPSHESEDFPRPLV 617

Query: 310 QHPG 313
             PG
Sbjct: 618 TLPG 621



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 9/113 (7%)

Query: 144 SSDPKDIDQDNRSTSPS-----IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 198
           SS P    Q+  +T+ S     IP  Q  ++ + +S     +Q  P  +  P GV P   
Sbjct: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP-- 576

Query: 199 SAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250
             PPG P  P P P  SA   +PP+G    S        P   +P    QQ P
Sbjct: 577 -LPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score =  105 bits (263), Expect = 2e-22
 Identities = 135/492 (27%), Positives = 173/492 (35%), Gaps = 116/492 (23%)

Query: 143  GSSDPKDIDQDNRSTSPSIPSPQDN---------------ESDSDSSAQQQMLQAQPPAL 187
            G  +P++ + D     P++P+   +                SDS SS Q  ML +   A 
Sbjct: 585  GPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAA 644

Query: 188  QAPTG-VTPAPSSAPPGTPQ-LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTH 245
             +P   V   P S  P  PQ LP+ G     TA P  G P  S       AP  P     
Sbjct: 645  PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAP--GLPVGSVP-----APACP----- 692

Query: 246  IQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 305
                P+L  Q  P P     P   PP  P+    GQP+ P    PPL  Q  P P  L  
Sbjct: 693  ----PSLQ-QHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPL-AQPTPLPQVLAP 746

Query: 306  GPLLQHPGPPQPFGLPP---QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
             P++  P  P P  LPP    ASQ  AP    P        LQ+P +     +Q PP+  
Sbjct: 747  QPVV--PLQPVPPHLPPYLAPASQVGAPAQLKP--------LQMPQAPLQPLAQVPPQMP 796

Query: 363  PLPPAPLAMPHI----KPP-----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 413
            P+P  P   P       PP     PT  +P +P PQ     P +  P   S+ A LPP  
Sbjct: 797  PIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFS--PAVILP---SLAAPLPPAS 851

Query: 414  ALKPLSSLSTHHPPSA------------HPPPLQLMPQSQP-------------LPSSPA 448
               PL ++   HPP A             P  + L+  + P             LP  P 
Sbjct: 852  PALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPV 911

Query: 449  QPPGLTQSQNLPPPPASHPPT-GLHQVAPQPPFAQHPFVPGGPPPITP--PTCPSTSTPP 505
             P    Q      PP+ H     +    PQP     P +P  P P+ P  PT P     P
Sbjct: 912  YPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP--PQPVLPPQPTLPPQPVLP 969

Query: 506  AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 565
              P    QP                  P P +           +P  PP P     PEP 
Sbjct: 970  PQPTRPPQPVLP---------------PQPML---------PPQPVLPPQPALPVRPEPL 1005

Query: 566  VVDTPSHASQSA 577
                P  A+ +A
Sbjct: 1006 QPHLPEQAAPAA 1017



 Score =  102 bits (253), Expect = 2e-21
 Identities = 146/547 (26%), Positives = 188/547 (34%), Gaps = 122/547 (22%)

Query: 118  QEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST-----SPSIPSPQDNESDSD 172
            Q +  P  P+     +SDS   + +GS+   D     +S      + + PSP        
Sbjct: 596  QHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPP 655

Query: 173  SSAQQQMLQAQPP--ALQAPT-------GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 223
             S    + Q+ P   A Q PT       G  PAP+  P      P P  +  A  +PP  
Sbjct: 656  VSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS-FAPVLPPPS 714

Query: 224  SPTASQAPNQPQAP-------TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP----- 271
            +P  +  P QP  P         P P   +     + P +P  PH PP+ +P        
Sbjct: 715  TPMPT-GPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPA 773

Query: 272  -LQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 330
             L+PL      P AP      +  Q PP P      PL    G P      P A+    P
Sbjct: 774  QLKPLQ----MPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVP 829

Query: 331  LGT--SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP--HIKP--PPTTPI-- 382
                 SPA   P  +  LP +  AL  Q      P P APLAMP   I P  P T P+  
Sbjct: 830  PPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHP-PGAPLAMPCRTIVPNAPATIPLLA 888

Query: 383  ---PQLPAPQAHKHPPHLSG-----------------PSPFSMNANL---PPPPALKPLS 419
               P + A   H     L G                 PSP     N+   PP PAL P  
Sbjct: 889  VAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQP 948

Query: 420  SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG--LTQSQNLPPPPASHPPTGLHQVAPQ 477
            +L    PP    PP   +P    LP  P +PP   L     LPP P   P   L  V P+
Sbjct: 949  TL----PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL-PVRPE 1003

Query: 478  P-------------------------PFA-----QHPFVPGGPPPITPPTCPSTSTPPAG 507
            P                         P+A     Q P VP  P  +  P  P    P A 
Sbjct: 1004 PLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLP-AA 1062

Query: 508  PGTSAQPPCSGAAASGG-----------------SIAGGS--SCPLPTVQIKEEALDDAE 548
            P    Q P S A  S                    + GG   + P PTVQ+  E + + +
Sbjct: 1063 PELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQ 1122

Query: 549  EPESPPP 555
              +  PP
Sbjct: 1123 ASQDKPP 1129



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 111/394 (28%), Positives = 141/394 (35%), Gaps = 60/394 (15%)

Query: 178  QMLQAQ-PPALQAPTGVTPAP-----------SSAPPGTPQLPT------PGPT------ 213
            QM QA   P  Q P  + P P              PP  P LPT      P P       
Sbjct: 779  QMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAV 838

Query: 214  --PSATAVPPQGSPT----ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 267
              PS  A  P  SP     A + P+ P AP A    T +  APA  P    +P      S
Sbjct: 839  ILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALS 898

Query: 268  PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 327
             H  +  L G    P+A     P      PP PH            PPQP  LPPQ +  
Sbjct: 899  IHSAVAQLPGQPVYPAAFPQMAPT---DVPPSPHHTVQN---MRATPPQP-ALPPQPTLP 951

Query: 328  QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH----IKPPPTTP-I 382
              P+   P    P   +  P      Q   PP+   LPP P+  P     ++P P  P +
Sbjct: 952  PQPV-LPPQPTLPPQPVLPPQPTRPPQPVLPPQPM-LPPQPVLPPQPALPVRPEPLQPHL 1009

Query: 383  PQLPAPQAHKHPPHLSG-PSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 439
            P+  AP A      L G P+P++++  A +P  P + P + LS   P    P   +L+PQ
Sbjct: 1010 PEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVP-VPPAAVLSPPLPEVLLPAAPELLPQ 1068

Query: 440  --------SQPLPSSPAQPPGLTQSQNLPPP--PASHPPTGLHQVAPQPPFAQHPFVPGG 489
                    S  + S P Q   L    N P P  P    P    Q+  +P   Q       
Sbjct: 1069 FPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEP--VQEEQASQD 1126

Query: 490  PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523
             PP  P +C S        G      C GA   G
Sbjct: 1127 KPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGG 1160



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 82/271 (30%), Positives = 101/271 (37%), Gaps = 36/271 (13%)

Query: 266  PSPHPPLQPLTG-SAGQPSAPSHAQPPLHGQGP--PGPHSLQAGPLLQHPGPPQP----- 317
            P   PP     G   G+ S  S A  P++ Q     G       P+ +HP P  P     
Sbjct: 1273 PGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPP 1332

Query: 318  ---FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 374
                 LPP+ASQ  AP     ++    + L   ASQ  L    P      PPAPLA    
Sbjct: 1333 LPLSSLPPEASQDSAPYKDQLSSKEQPSFL---ASQQLLSQAGPSNPPGAPPAPLAP--- 1386

Query: 375  KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP--LSSLSTHHP-PSAHP 431
              PP T +PQ  A      P   + P P S  A+    P       S L T  P    H 
Sbjct: 1387 SSPPVTALPQDGAA-----PATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHE 1441

Query: 432  PPLQLMPQSQPL-PSSPAQPPGLTQSQN-----LPPPPASHPPTGLHQVAPQPPFAQ-HP 484
             PL + P    L P +PA     T+  +     LPPP     P   H   PQP   Q  P
Sbjct: 1442 APLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP---HSGTPQPALGQPAP 1498

Query: 485  FVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 515
             +P     ++  T    S PP GP    QPP
Sbjct: 1499 LLPAAVGAVSLATSQLPS-PPLGPTVPPQPP 1528



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 88/312 (28%), Positives = 105/312 (33%), Gaps = 56/312 (17%)

Query: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ--HPGPPQP-------FGLPPQASQGQAPL 331
           QP        P   +GPP P  +Q     Q   PGPP+P         LPP        L
Sbjct: 551 QPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSL 610

Query: 332 GTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP---LAMPHIKPPPTTPIPQLPAP 388
            +         S     SQS+ QS          P+P   +  P +   P  P   LP+ 
Sbjct: 611 ASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLP-QSLPSL 669

Query: 389 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 448
            A++ P    G     +     P PA  P  SL  H P  A      L P S P+P+ P 
Sbjct: 670 GAYQQPTAAPG-----LPVGSVPAPACPP--SLQQHFPDPAMSFAPVLPPPSTPMPTGPG 722

Query: 449 QPPGLTQSQNLPPPPASHPPTGLHQV-APQPPFAQHPFVPGGPPPITP------------ 495
           QP    Q    PPP A   PT L QV APQP     P  P  PP + P            
Sbjct: 723 QPAPPGQQ---PPPLAQ--PTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKP 777

Query: 496 ------PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 549
                 P  P    PP  P     PP +  A   G        P  TV            
Sbjct: 778 LQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATV------------ 825

Query: 550 PESPPPPPRSPS 561
           P  PPP   SP+
Sbjct: 826 PPVPPPQYFSPA 837



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 84/336 (25%), Positives = 110/336 (32%), Gaps = 78/336 (23%)

Query: 148  KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ-------------APTGVT 194
            +D D D R + P    P  +     +  + +  QA  P  Q              P    
Sbjct: 1263 EDTDAD-RGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEH 1321

Query: 195  PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 254
            PAP  AP  +P LP        +++PP+ S  ++   +Q  +   P      Q      P
Sbjct: 1322 PAPE-APESSPPLPL-------SSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP 1373

Query: 255  QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314
              PP   P P     PP+  L      P+  +  +P              +G   Q  GP
Sbjct: 1374 SNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPA-------------SGTASQAGGP 1420

Query: 315  PQPFGLP-------PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 367
              P GL        P A   +APL   P           P + S  +    PRE   PPA
Sbjct: 1421 GTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAST-RDASAPREPLPPPA 1479

Query: 368  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 427
            P   PH      TP P L  P                     P  PA     SL+T   P
Sbjct: 1480 PEPSPH----SGTPQPALGQP--------------------APLLPAAVGAVSLATSQLP 1515

Query: 428  SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463
            S   PPL         P+ P QPP   +S    PPP
Sbjct: 1516 S---PPLG--------PTVPPQPPSALESDGEGPPP 1540



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 86/321 (26%), Positives = 116/321 (36%), Gaps = 65/321 (20%)

Query: 83   KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 142
            +E     +K    + E + S+  +ADR S   T     S P+  + G G   +SR     
Sbjct: 1243 RETFIEQMKDVMDKAEDMLSEDTDADRGSDPGT-----SPPHLSTCGLGTGEESRQSQAN 1297

Query: 143  GSSDPKDIDQDNR-----------------STSPSIPS---PQDNESDSDSSAQQQMLQA 182
                 +++    +                  +SP +P    P +   DS     Q   + 
Sbjct: 1298 APVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKE 1357

Query: 183  QPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG------------SPTASQA 230
            QP  L +   ++ A  S PPG P  P    +P  TA+P  G            S TASQA
Sbjct: 1358 QPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQA 1417

Query: 231  --PNQPQAPTA------PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP 282
              P  PQ  T+      P+  TH  +AP L  Q       P  P+P         S    
Sbjct: 1418 GGPGTPQGLTSELETSQPLAETH--EAP-LAVQPLVVGLAPCTPAPE------AASTRDA 1468

Query: 283  SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342
            SAP    PP   +  P PHS    P L  P P  P      A+ G   L TS   + P  
Sbjct: 1469 SAPREPLPPPAPE--PSPHSGTPQPALGQPAPLLP------AAVGAVSLATSQLPSPPLG 1520

Query: 343  SLQLPASQSALQSQ---QPPR 360
                P   SAL+S     PPR
Sbjct: 1521 PTVPPQPPSALESDGEGPPPR 1541



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 64/269 (23%), Positives = 89/269 (33%), Gaps = 73/269 (27%)

Query: 329  APLGTSPAAAYPHTSL-QLPASQSALQSQQ--------------------PPREQPLPPA 367
            A  G+ P  + PH S   L   + + QSQ                     P  E P P A
Sbjct: 1267 ADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEA 1326

Query: 368  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 427
            P + P   P P + +P   +  +  +   LS     S  A+       + LS     +PP
Sbjct: 1327 PESSP---PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQ------QLLSQAGPSNPP 1377

Query: 428  SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHP---------PTGL-HQVAPQ 477
             A  PP  L P S P+ + P    G   + +  P PAS           P GL  ++   
Sbjct: 1378 GA--PPAPLAPSSPPVTALPQD--GAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS 1433

Query: 478  PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 537
             P A+    P    P+     P T  P A     A  P                 PLP  
Sbjct: 1434 QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPRE---------------PLP-- 1476

Query: 538  QIKEEALDDAEEPESPPPPPRSPSPEPTV 566
                        P +P P P S +P+P +
Sbjct: 1477 ------------PPAPEPSPHSGTPQPAL 1493



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 48/206 (23%), Positives = 59/206 (28%), Gaps = 60/206 (29%)

Query: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQ-------SQPLPSSPAQPPGLTQSQNLPPPPAS 465
           PAL+P        P  A  PP+ L  Q        QP P  P +P      Q+L PP   
Sbjct: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEA---DQHLLPPTLP 604

Query: 466 HPPTGL-------------------------------------HQVAPQPPFAQHPFVPG 488
              T L                                      Q    PP ++ P +P 
Sbjct: 605 TSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQ 664

Query: 489 GPP-------PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKE 541
             P       P   P  P  S P      S Q      A S   +    S P+PT     
Sbjct: 665 SLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT----- 719

Query: 542 EALDDAEEPESPPPPPRSPSPEPTVV 567
                   P   PPP   P+P P V+
Sbjct: 720 -GPGQPAPPGQQPPPLAQPTPLPQVL 744



 Score = 34.7 bits (78), Expect = 0.47
 Identities = 37/145 (25%), Positives = 49/145 (33%), Gaps = 12/145 (8%)

Query: 275 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 334
           + G  G+   P     P  G GP G    +A      PGP +        S  + P G  
Sbjct: 1   MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAA--RPGPQRFLRRSVVESDQEEPPGLE 58

Query: 335 PAAA---YPHTSLQ---LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 388
            A A    P   LQ   L   ++     +  R +P  PAP A+      P  P    P P
Sbjct: 59  AAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEP 118

Query: 389 QAHKHPPHLSGPSPFSMNANLPPPP 413
              + P    GP P +      P P
Sbjct: 119 VGTQEP----GPDPIAAAVETAPAP 139



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 5/97 (5%)

Query: 884 LHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFG- 942
           L Q  P    S  PV P   P T  P     P PPG  P PL    P    +   PV   
Sbjct: 695 LQQHFPDPAMSFAPVLP--PPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPL 752

Query: 943 TPYPRDLPGAIPP--PMSAAHQLQAMHAQSAELQRLA 977
            P P  LP  + P   + A  QL+ +    A LQ LA
Sbjct: 753 QPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLA 789



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 184 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238
           P AL A  G   AP+ A P       PGP P A AV  + +P     P +  A T
Sbjct: 98  PAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAV--ETAPAPDGGPREEAAAT 150



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 49/218 (22%), Positives = 87/218 (39%), Gaps = 13/218 (5%)

Query: 28   STLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAA-----STSSNDSKAETVKKSAKKV 82
            ST  SG+  Q   P    + ++ DI S   +    A     +     S+  T K S+K  
Sbjct: 2000 STGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGWTVYHPTSERVTYKSSSKPR 2059

Query: 83   KEEASSPLK-SNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 141
                S P+  S     +++    E + R+S+          P      + + ++S +   
Sbjct: 2060 ARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPALHVQAQVNNSNNKKG 2119

Query: 142  EGSSD-PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS- 199
              + D  K +D+    TS ++ + Q   + +     Q++   +  A  A  G   A ++ 
Sbjct: 2120 TFTDDLHKLVDE---WTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAP 2176

Query: 200  -APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236
             A  G P+LP P P P +T V P  +PT S     P++
Sbjct: 2177 RAGVGMPRLP-PAPGPLSTTVIPGAAPTLSVPTPDPES 2213



 Score = 30.4 bits (67), Expect = 8.8
 Identities = 30/126 (23%), Positives = 39/126 (30%), Gaps = 27/126 (21%)

Query: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261
           PGT   P  G  P+  A P       +  P   +     V  +  ++ P L     P P 
Sbjct: 11  PGTLMEPGRGAGPAGMAEPR----AKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQ 66

Query: 262 PPP----------------------HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 299
           PP                        P+   P   L    G P AP+ A P   G   PG
Sbjct: 67  PPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAA-LVAQPGAPGAPADAGPEPVGTQEPG 125

Query: 300 PHSLQA 305
           P  + A
Sbjct: 126 PDPIAA 131


>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
            sapiens]
          Length = 1235

 Score =  104 bits (260), Expect = 4e-22
 Identities = 242/1102 (21%), Positives = 347/1102 (31%), Gaps = 308/1102 (27%)

Query: 76   KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 134
            KK  K +++             E  + +++   R+SS+    + +S  ++PS  G G   
Sbjct: 166  KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221

Query: 135  DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 171
            DS S  +E +SD                       P+   QD     P I   + ++  S
Sbjct: 222  DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281

Query: 172  DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 228
                ++ + +  P  L+ P      P   P   PQL  P P P     T  PPQ  P ++
Sbjct: 282  QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339

Query: 229  QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPP------------HPSPHPPLQPLT 276
            Q P  P       P   +Q AP    QRPP P  P             HPS     QPL+
Sbjct: 340  QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS 392

Query: 277  G-----------SAGQPSAPSHAQPPL-----HGQGPPGPHSL-------QAGPLLQHPG 313
                        S+ + S P+  QP       H    P P SL          P LQ P 
Sbjct: 393  AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPA 452

Query: 314  ---------PPQPFGLPPQASQGQAPLGTSPAAAY--PHTSLQLPASQSALQSQQPPREQ 362
                     PP     PP  + G   +   PA +       L+   +   L SQ   R  
Sbjct: 453  HSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGA 512

Query: 363  PLPPAPLA-------------------------MPHIKPPPTTPIPQLPAPQA------- 390
             L P P                            PH  PP  T I   PAP         
Sbjct: 513  SLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPP--TAIMPTPAPPMFDKYPTK 570

Query: 391  ----------HKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHP 426
                      H +PP +SG  P              F      P  P L+        H 
Sbjct: 571  VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHV 630

Query: 427  PSA-----HPPPLQLMPQSQP-------LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474
              A     H   ++   QS P        P   ++PPG +    +  P     P+ L   
Sbjct: 631  HIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSA 690

Query: 475  APQPPFAQHPF-VPGGPPP-----------ITPPTCPSTSTPPAGPGTSAQPPCSGAAAS 522
            A     A HP   P GPPP           + P   PST T  A  G +A       + +
Sbjct: 691  AG----AAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVT 746

Query: 523  GGSIAGGSSCPLPTVQIKEEALDDAEEPESP-----PPPPRSPSPEPTVVDTPSHASQSA 577
              S+ G    P         ++ +   P  P       PP  P+P P +       S SA
Sbjct: 747  PNSMFGHKDGP---------SVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASA 797

Query: 578  RFY---KHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK------------------- 615
              +   + +D+  +S ++ D             K  E++EK                   
Sbjct: 798  AAHDRDRDVDKRDSSVSKDD-------------KERESVEKRHSSHPSPAPVLPVNALGH 844

Query: 616  AKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMR 675
             +   EQ         +EK+K +ERER+     +  A     A EG L  P+  G GH  
Sbjct: 845  TRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL--PEKDGHGHEG 902

Query: 676  PSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM 735
             +       +A VP             S Y R  V+     N        P     AY  
Sbjct: 903  RAAGEEAKQLARVP-------------SPYVRTPVVESARPNSTSSREAEPRKGEPAYEN 949

Query: 736  PGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFAR 795
            P           ++  E +++E    + +L           PPE    H A+ P      
Sbjct: 950  P-----------KKSSEVKVKEERKEDHDL-----------PPEAPQTHRASEP------ 981

Query: 796  HSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERM--A 853
                  PP   P+  +S HPG  PL    + +    + P M+    L   R+    M  +
Sbjct: 982  ------PP---PNSSSSVHPG--PLASMPMTVGVTGIHP-MNSISSLDRTRMMTPFMGIS 1029

Query: 854  SLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG---SAGPVHPLVDP------ 904
             L          F+  P        +  L +H++DPL +       P+H L  P      
Sbjct: 1030 PLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEAD 1089

Query: 905  ---LTAGPHLARFPYPPGTLPNPLLGQPPHEHE------------MLR----HPVFGTPY 945
                   PH   + +      +PL   P  EHE            MLR    H    + +
Sbjct: 1090 RSFRDREPH--DYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVH 1147

Query: 946  PRDLPGAIPPPMSAAHQLQAMH 967
            P  L G +P P      L +MH
Sbjct: 1148 PASLDGHLPHPSLITPGLPSMH 1169


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score =  104 bits (260), Expect = 4e-22
 Identities = 124/418 (29%), Positives = 152/418 (36%), Gaps = 84/418 (20%)

Query: 183 QPPALQAPTGVTPAPSSAP---PGTPQLP--TPGPTPSATAVPPQGSPTASQ--APNQPQ 235
           Q P L  P+   P P+  P   PG P+ P  TPGP P++ + PP+  P   Q  AP  PQ
Sbjct: 400 QVPLLPVPS--QPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPR-LPLQDQWRAPPPPQ 456

Query: 236 -----------APTAPVPHTHIQQAPALHPQRPP----SPHPPPHPSPHPPLQP---LTG 277
                       P  P  H  ++Q     P  PP    S HP P  SP P  QP      
Sbjct: 457 DRDPFFLGVSGEPRFP-SHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQ 515

Query: 278 SAGQPSAPSH--AQPPLHGQGPPG------PHSLQAGPLLQH-----PGPPQPFGLPPQA 324
              QP  P     +P L   GP G      P S    P +       PGP QPF LP   
Sbjct: 516 QGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPF-LPTHT 574

Query: 325 SQG-QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 383
               Q PL   P    PH        Q      QPP + P  P P      +PPP  P  
Sbjct: 575 QPNLQGPL--HPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPP----QHQPPPQHPPQ 628

Query: 384 QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 443
             P  Q H H  HLS            PPP L P+S       P   P      PQ+   
Sbjct: 629 HPPQHQHHHHHHHLS-----------VPPPPLMPMSQ------PQFRPHVQTAQPQASSS 671

Query: 444 PSSPAQPPGL---TQSQNLPPPPASHPPTGLHQVAPQPP----FAQHPFVPGGPPPITPP 496
                Q  GL   T SQN+   P       + Q+ P  P      + P  P     ++  
Sbjct: 672 RMQCPQRQGLRHNTTSQNVSKRP-------MQQMQPTAPRNSNLRELPIAPSHVIEMSSS 724

Query: 497 TCPSTSTPPAGPGTSAQPP---CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 551
            C +T +    P  SA PP    +G+ +S G          P  Q KEEA  + E P+
Sbjct: 725 RCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPD 782



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 147/572 (25%), Positives = 197/572 (34%), Gaps = 174/572 (30%)

Query: 201 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 260
           PP  PQ P P P P      PQ  P  S    QP  P  PV H H       HP  P   
Sbjct: 313 PPVVPQAPPPPPPP------PQQQPIRSLFQPQPLQPLLPVQHPH-------HPSPPQGM 359

Query: 261 HPPPH---------PSPHPPLQP--------LTGSAGQP------SAPSHAQPPLHGQGP 297
           H PP          P P  P QP          G+   P        PS  +P +  Q  
Sbjct: 360 HMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF 419

Query: 298 PGPHSLQAGPLLQH-PGP-PQPFGLPPQ---ASQGQAP----------LGTSPAAAYPH- 341
           PGP         QH PGP P  F  PP+     Q +AP          LG S    +P  
Sbjct: 420 PGPPEFP-----QHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSH 474

Query: 342 -------------------------TSLQLPASQSA----LQSQQP--PREQPL-----P 365
                                    T   LP +Q       Q QQP  PRE+P+     P
Sbjct: 475 LFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQP 534

Query: 366 PAPLAMPHIKPP---PTTPI-----PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 417
           P P+ + H   P    T P      P LP P     P H        ++  LPPP     
Sbjct: 535 PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP----- 589

Query: 418 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP--PASHPPTGLHQVA 475
                  H P    P  Q  PQ QP    P QPP     Q+ PPP  P  HPP   H   
Sbjct: 590 -------HQPQPQQPQQQPPPQHQP----PHQPPHQPPPQHQPPPQHPPQHPPQHQHH-- 636

Query: 476 PQPPFAQHPFVPGGPPPITPPTCP------STSTPPAGPGTSAQPPCSGAAASGGSIAGG 529
                  H  +   PPP+ P + P       T+ P A   +S++  C        +    
Sbjct: 637 -----HHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQA---SSSRMQCPQRQGLRHNTTSQ 688

Query: 530 SSCPLPTVQIKEEALDDAEEPESPPPPPR---------SPSPEPTV-----VDTPSHASQ 575
           +    P  Q++  A  ++   E P  P           S +P   V        PS A  
Sbjct: 689 NVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVA 748

Query: 576 SARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA--------------IEKAKREAE 621
            +R         +S  +T++   P   S +A+ +EEA              + + K E +
Sbjct: 749 GSR---------SSQGKTEVKVKP--ASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQ 797

Query: 622 QKAREEREREKEKEKEREREREREREAERAAK 653
           ++ REE  ++KE  ++++    ++   ER A+
Sbjct: 798 KRLREEILKQKELRRQQQAGARKKELLERLAQ 829



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 161/731 (22%), Positives = 238/731 (32%), Gaps = 139/731 (19%)

Query: 250 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 309
           PAL P +PP     P P P PP Q    S  QP       P  H      PH        
Sbjct: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQH------PH-------- 351

Query: 310 QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 369
            HP PPQ   +PPQ                    L+ P          PP   P  P  +
Sbjct: 352 -HPSPPQGMHMPPQ--------------------LETPR-----MMMTPPPVTPQQPKNI 385

Query: 370 AM-PHIKPPPTTP--IPQLPAPQAHK---HPPHLSGPSPFSMNANLPPPPALKPLSSLST 423
            + PH K    TP  +P LP P   +    P    GP  F  +   P P +      L  
Sbjct: 386 HINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPL 445

Query: 424 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 483
                A PPP    P    +   P  P  L   Q  PPPP   PPT L+   P P  +  
Sbjct: 446 QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP-PPTLLNSSHPVPTQSPL 504

Query: 484 PFVPGGP-------PPITP---PTCPSTSTP-PAG------PGTSAQ----PPCSGAAAS 522
           PF   GP        P+ P   P  P+   P P G      PG++      PP       
Sbjct: 505 PFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPG 564

Query: 523 GG----------SIAGGSSCPLPTV-QIKEEALDDAEEPESPPP--PPRSPSP--EPTVV 567
            G          ++ G    PLP   Q + +       P+  PP  PP  P P  +P   
Sbjct: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624

Query: 568 DTPSHASQSARFYKHLDRGYNS---CARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 624
             P H  Q    + H             +   F P   +   +     ++  +R+  +  
Sbjct: 625 HPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHN 684

Query: 625 REEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRP--SFEPPP 682
              +   K   ++ +    R         A S   E   S    +    ++P  S  PP 
Sbjct: 685 TTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPS 744

Query: 683 TTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVD 742
             +A      G     ++  S  A+P   + T    P     +  +    Y +       
Sbjct: 745 RAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFP-----DEDEETRLYRLK--IEEQ 797

Query: 743 PTIRERELREREIRERE---IRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 799
             +RE  L+++E+R ++    R++EL ER+         +   L+    P E      AL
Sbjct: 798 KRLREEILKQKELRRQQQAGARKKELLERL-------AQQQQQLYAPPPPAEQ--EEQAL 848

Query: 800 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP 859
           +  PT G           NPL    L   G Q+R  +     +  + +    +   TS+ 
Sbjct: 849 SPSPTNG-----------NPL----LPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNF 893

Query: 860 LARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPG 919
           +      +     +Q   + +  HL Q   + Q    P+H ++            P  P 
Sbjct: 894 VP-----SSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVL------------PIKPA 936

Query: 920 TLPNPLLGQPP 930
            +  P + Q P
Sbjct: 937 DVEEPAVPQTP 947



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 77/276 (27%), Positives = 90/276 (32%), Gaps = 47/276 (17%)

Query: 147 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ 206
           P  +  + RS  P  P P    S      Q  +   QP       G  P      P  P 
Sbjct: 472 PSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPA 531

Query: 207 LPTPGPT--------PSATAVP--PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR 256
           L  PGP          SAT  P  P   P     P QP  PT    HT       LHP  
Sbjct: 532 LQPPGPVGILHFSQPGSATTRPFIPPRQPFL-PGPGQPFLPT----HTQPNLQGPLHP-- 584

Query: 257 PPSPHPPPH-PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH---- 311
              P PPPH P P  P Q        P  P H  PP H   PP  H  Q  P  QH    
Sbjct: 585 ---PLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQH--QPPPQHPPQHPPQHQHHHHH 639

Query: 312 ------PGPPQPFGLP----------PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQS 355
                 P P  P   P          PQAS  +  +         H +     S+  +Q 
Sbjct: 640 HHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSR--MQCPQRQGLRHNTTSQNVSKRPMQQ 697

Query: 356 QQP--PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 389
            QP  PR   L   P+A  H+    ++     P+ Q
Sbjct: 698 MQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQ 733



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 83/414 (20%), Positives = 134/414 (32%), Gaps = 53/414 (12%)

Query: 28   STLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAS 87
            +T      K+P      T+P N ++R      P A S     S +      + +VK    
Sbjct: 684  NTTSQNVSKRPMQQMQPTAPRNSNLREL----PIAPSHVIEMSSSRCSATPSAQVK---- 735

Query: 88   SPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS--------V 139
             P+ S       VA       +T  K      +++P   ++ E E  D           +
Sbjct: 736  -PIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKI 794

Query: 140  NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 199
             ++     + + Q          + +    +  +  QQQ+    PPA Q    ++P+P++
Sbjct: 795  EEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTN 854

Query: 200  APPGTPQLPTPGP-----TPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALH 253
               G P LP PG        +   V  Q    ++  P      P++       QQ  AL 
Sbjct: 855  ---GNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALK 911

Query: 254  PQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 312
              R     P     P H  L        +P+ P            P   S+Q  P    P
Sbjct: 912  HLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQ----------TPRVASIQGRPQDTKP 961

Query: 313  GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372
            G  +       +  G  P  +S        S     S      +  P+  P P      P
Sbjct: 962  GVKRTVTHRTNSGGGDGPHISSKVRVI-KLSGGGGESDGFFHPEGQPQRLPQP------P 1014

Query: 373  HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
             + P P   +         + PPHL    P   +A+ P PP +K +  +   HP
Sbjct: 1015 EVGPQPARKVTLTRG--GLQQPPHL----PAGPHAHSPVPPGIKSIQGI---HP 1059



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 48/174 (27%), Positives = 62/174 (35%), Gaps = 32/174 (18%)

Query: 393 HPPHLSGPSPFSMNANLPPPPAL---KPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPSSPA 448
           H P L    P  +    PPPP     +P+ SL         P PLQ L+P   P   SP 
Sbjct: 304 HRPALLPTQPPVVPQAPPPPPPPPQQQPIRSL-------FQPQPLQPLLPVQHPHHPSPP 356

Query: 449 Q----PPGLTQSQNL--PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502
           Q    PP L   + +  PPP     P  +H     P F      P   P +  P+ P   
Sbjct: 357 QGMHMPPQLETPRMMMTPPPVTPQQPKNIH---INPHFKGTVVTPVQVPLLPVPSQP--- 410

Query: 503 TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP 556
            P  GP     PP       G         P+P    +   L   ++  +PPPP
Sbjct: 411 RPAVGPQRFPGPPEFPQHTPG---------PVPNSFSQPPRLPLQDQWRAPPPP 455



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 96/418 (22%), Positives = 140/418 (33%), Gaps = 69/418 (16%)

Query: 603 SKLAKKREEAIEKAKREAEQKAR--EEREREKEKEKEREREREREREAERAA------KA 654
           S + ++R    E  +  AE KA   E  ERE++ ++ R   R   R            + 
Sbjct: 233 SDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQR 292

Query: 655 SSSAHEGRLSDPQLSGPGHMRPSFEP--PPTTIAAVPPYIGPDTPALRTLSEYARPHVMS 712
             S   GR+ D         RP+  P  PP    A PP   P  P  + +    +P  + 
Sbjct: 293 RESTERGRMKDH--------RPALLPTQPPVVPQAPPP--PPPPPQQQPIRSLFQPQPLQ 342

Query: 713 PTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPG 772
           P     P   P +P+ P    HMP        +    +    +  ++ +   +    K G
Sbjct: 343 PLL---PVQHPHHPSPPQ-GMHMPPQLETPRMM----MTPPPVTPQQPKNIHINPHFK-G 393

Query: 773 FEVKPPELDPLHPAANPMEHFARHSALTIPP-----TAGPHPFASFHPGLNPLERERLAL 827
             V P ++ PL P  +             PP     T GP P +   P   PL+ +  A 
Sbjct: 394 TVVTPVQV-PLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAP 452

Query: 828 AGPQLRP--------EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIH 879
             PQ R         E  +P  L  E    +R       P   L   +  P         
Sbjct: 453 PPPQDRDPFFLGVSGEPRFPSHLFLE----QRSPPPPPPPPTLLNSSHPVP-------TQ 501

Query: 880 SHLHLHQQDP-LHQGSAGPVHPLVDPLTA-----GP-HLARFPYPPGTLPNPLLGQPPHE 932
           S L   Q  P  +Q    PV P   P+       GP  +  F  P      P +  PP +
Sbjct: 502 SPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFI--PPRQ 559

Query: 933 HEMLR--HPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPH 988
             +     P   T    +L G + PP+   HQ Q    Q    Q+   + Q  H  PH
Sbjct: 560 PFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ----QQPPPQHQPPHQPPH 613



 Score = 33.9 bits (76), Expect = 0.80
 Identities = 42/168 (25%), Positives = 55/168 (32%), Gaps = 30/168 (17%)

Query: 803 PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LA 861
           PT  P PF    P  N   ++ +      +RP +  P  +    +H  +  S T+ P + 
Sbjct: 499 PTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI--LHFSQPGSATTRPFIP 556

Query: 862 RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTL 921
             Q F   P           L  H Q  L     GP+HP              P PP   
Sbjct: 557 PRQPFLPGPGQ-------PFLPTHTQPNLQ----GPLHP--------------PLPPPHQ 591

Query: 922 PNPLLGQ--PPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMH 967
           P P   Q  PP +H+    P    P     P   PP     HQ    H
Sbjct: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHH 639


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,118,291
Number of Sequences: 37866
Number of extensions: 5067069
Number of successful extensions: 133584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1468
Number of HSP's successfully gapped in prelim test: 3525
Number of HSP's that attempted gapping in prelim test: 30597
Number of HSP's gapped (non-prelim): 47548
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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