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Search of human proteins with 11225260
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11225260 DNA topoisomerase I [Homo sapiens]
(765 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11225260 DNA topoisomerase I [Homo sapiens] 1577 0.0
gi|16418461 mitochondrial topoisomerase I [Homo sapiens] 863 0.0
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 84 4e-16
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 82 1e-15
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 82 1e-15
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 81 3e-15
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 80 9e-15
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 79 1e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 78 4e-14
gi|4557509 cylicin 2 [Homo sapiens] 77 6e-14
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 75 2e-13
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 72 3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 7e-12
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 70 7e-12
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 69 1e-11
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 69 2e-11
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 68 4e-11
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 68 4e-11
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 68 4e-11
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap... 68 4e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 5e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 8e-11
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 66 1e-10
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 65 2e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 65 3e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 4e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 4e-10
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 64 4e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 64 4e-10
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 64 5e-10
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 1577 bits (4084), Expect = 0.0
Identities = 765/765 (100%), Positives = 765/765 (100%)
Query: 1 MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKK 60
MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKK
Sbjct: 1 MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKK 60
Query: 61 HKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEP 120
HKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEP
Sbjct: 61 HKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEP 120
Query: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD 180
EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD
Sbjct: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD 180
Query: 181 KDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKF 240
KDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKF
Sbjct: 181 KDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKF 240
Query: 241 YYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKC 300
YYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKC
Sbjct: 241 YYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKC 300
Query: 301 DFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGL 360
DFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGL
Sbjct: 301 DFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGL 360
Query: 361 FRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENI 420
FRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENI
Sbjct: 361 FRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENI 420
Query: 421 QGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALY 480
QGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALY
Sbjct: 421 QGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALY 480
Query: 481 FIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNK 540
FIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNK
Sbjct: 481 FIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNK 540
Query: 541 VPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQ 600
VPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQ
Sbjct: 541 VPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQ 600
Query: 601 QLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLAD 660
QLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLAD
Sbjct: 601 QLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLAD 660
Query: 661 ARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSK 720
ARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSK
Sbjct: 661 ARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSK 720
Query: 721 LNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
LNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF
Sbjct: 721 LNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
>gi|16418461 mitochondrial topoisomerase I [Homo sapiens]
Length = 601
Score = 863 bits (2230), Expect = 0.0
Identities = 402/584 (68%), Positives = 493/584 (84%), Gaps = 2/584 (0%)
Query: 184 KVPEPDNKKKKPKKEEEQKWKW--WEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFY 241
+VP + P QK WE+E++ +G+KW+ LEHKGP FAPPYEPLP+ V+F+
Sbjct: 18 EVPRRPASRGVPGSRRTQKGSGARWEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFF 77
Query: 242 YDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCD 301
Y+G+ ++LS AEEVATF+ +MLDHEYTTKE+FRKNFF DWRKEM EE+ +I +L KCD
Sbjct: 78 YEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCD 137
Query: 302 FTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLF 361
FT++ +YF + ARK +S+EEK K+KEE EKL +E+G+CI+D H+E+I NFKIEPPGLF
Sbjct: 138 FTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLF 197
Query: 362 RGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQ 421
RGRG+HPKMGMLKRRI PED++INCS+D+K+P PP GH+WKEVR DN VTWL +WTE++Q
Sbjct: 198 RGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQ 257
Query: 422 GSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYF 481
SIKYIMLNP S++KGE WQK+ETARRL+ VD+IR+QYR DWKS+EMK RQRAVALYF
Sbjct: 258 NSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYF 317
Query: 482 IDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKV 541
IDKLALRAGNEKE+GE ADTVGCCSLRVEH+ LHPE DG ++VVEFDFLGKD IRYYN+V
Sbjct: 318 IDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRV 377
Query: 542 PVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQ 601
PVEK V+KNLQLFMENK P DDLFDRL T LNKHLQ+LM+GLTAKVFRTYNASITLQ+Q
Sbjct: 378 PVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQ 437
Query: 602 LKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADA 661
L+ LT +++I AKILSYNRANR VAILCNHQRA P TFEKSM NLQTKI AKKEQ+A+A
Sbjct: 438 LRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEA 497
Query: 662 RRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKL 721
R +L+ A+A+ K D K++ V+E K++ +++L+EQL +L VQATD+EENKQ+ALGTSKL
Sbjct: 498 RAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKL 557
Query: 722 NYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
NYLDPRI++AWCK++ VP+EKIY+KTQRE+FAWA+ MA ED+EF
Sbjct: 558 NYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 84.3 bits (207), Expect = 4e-16
Identities = 70/221 (31%), Positives = 105/221 (47%), Gaps = 53/221 (23%)
Query: 20 DSHKHKDKHKDR-EHRHKEHKKEKDREKSKHSNSEHKDSEK-------KHKEKE------ 65
D + KDK+KD+ + + K +KEKD+E + + K+ K K K KE
Sbjct: 541 DREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDP 600
Query: 66 KTKHKDG----SSEKHKDKHKDR-----DKEKRKEEKVRASGDAKIKKEKENGFSSPPQI 116
K K KDG EKHKDK KDR DK+KR++EKV+ G +E + +PP +
Sbjct: 601 KVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKG-----REDKMKAPAPPLV 655
Query: 117 KDEPEDDGYFVPPKEDIKPLKRPRDEDDADY---------------KPKKIKTEDTKKEK 161
+PPKE PL P + +K+K ++ KK+K
Sbjct: 656 ----------LPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDK 705
Query: 162 KRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
K K +++E K KK K ++K+K+ E K+K+ K E+ K
Sbjct: 706 KEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIK 746
Score = 64.3 bits (155), Expect = 4e-10
Identities = 82/314 (26%), Positives = 125/314 (39%), Gaps = 75/314 (23%)
Query: 28 HKDREHRHKEHKKEKDREK-SKHSNSEHKDSEKKH-KEKEKTKHKDGSSEKHKDKHKDRD 85
HK E + K + ++K K ++ K EK+ +E+EK K+KD S EK K K K++D
Sbjct: 506 HKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKD 565
Query: 86 KEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDA 145
KE +E K P KE +K E++A
Sbjct: 566 KETGRETK---------------------------------YPWKEFLK-------EEEA 585
Query: 146 D-YKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWK 204
D YK K + ED + K K DG ++K K K KDKK KK K K+E+E+
Sbjct: 586 DPYKFKIKEFEDVDPKVKLK-----DGLVRKEKEKHKDKKKDREKGKKDKDKREKEK--- 637
Query: 205 WWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSP-KAEEVATFFAKM 263
+K K E K APP P+ + + SP A V +
Sbjct: 638 ----------VKDKGREDKMKAPAPPLVLPPKEL------ALPLFSPATASRVPAMLPSL 681
Query: 264 LDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEE 323
L + + F++ K E+K K + + K + + +++ K E
Sbjct: 682 L-------PVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKRE 734
Query: 324 KLKIKEENEKLLKE 337
K K K ++EK+ E
Sbjct: 735 KEKEKHKHEKIKVE 748
Score = 52.0 bits (123), Expect = 2e-06
Identities = 43/140 (30%), Positives = 60/140 (42%), Gaps = 41/140 (29%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDS---------------------- 57
+ KHKDK KDRE + K+ K ++++EK K E K
Sbjct: 612 EKEKHKDKKKDRE-KGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPAT 670
Query: 58 ----------------EKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGD-A 100
EK +EKEK K K+ +K K+K K ++KEK K+EK R
Sbjct: 671 ASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDK-KEKKKKKEKEKEKKEKEREKEKRE 729
Query: 101 KIKKEKENGFSSPPQIKDEP 120
+ K+EKE +IK EP
Sbjct: 730 REKREKEKEKHKHEKIKVEP 749
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/63 (41%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
Query: 32 EHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKE 91
E + K +KEK ++K + + K+ EKK KE+EK K + EK K+KHK EK K
Sbjct: 691 EEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHK---HEKIKV 747
Query: 92 EKV 94
E V
Sbjct: 748 EPV 750
Score = 47.4 bits (111), Expect = 5e-05
Identities = 22/55 (40%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Query: 16 FRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHK 70
F + K K+K KD++ + K+ +KEK++ K K E ++ EK+ KEKEK KH+
Sbjct: 690 FEEKEKVKEKEKKKDKKEKKKKKEKEKEK-KEKEREKEKREREKREKEKEKHKHE 743
Score = 30.0 bits (66), Expect = 8.4
Identities = 13/47 (27%), Positives = 23/47 (48%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHK 55
+ + + D + K K+K K + R KE ++ + REK K + K
Sbjct: 698 EKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEK 744
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 82.4 bits (202), Expect = 1e-15
Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 12/205 (5%)
Query: 7 HNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEK---KHKE 63
HN S+ R HK + K RE R K + R+K K + + K+ E+ K +E
Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERR-KSRSRSHSRDKRKDTREKIKEKERVKEKDRE 396
Query: 64 KEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDD 123
KE+ + K+ EK + K+KDRDKE+ K+ + D + ++EKE+ + E E D
Sbjct: 397 KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH--EKDRDKEKEKEQD 454
Query: 124 GYFVPPKEDIKPLKRPRDEDDADYKPKKI-----KTEDTKKEKKRKLEEEEDGKLKKPKN 178
K+ K + R +D P + ++ + +E++R+ + K
Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514
Query: 179 -KDKDKKVPEPDNKKKKPKKEEEQK 202
K K + P P ++ KK KK E+++
Sbjct: 515 IKRKSSRSPSPRSRNKKDKKREKER 539
Score = 77.0 bits (188), Expect = 6e-14
Identities = 56/214 (26%), Positives = 99/214 (46%), Gaps = 36/214 (16%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K KD+ K+RE R KE +KEK+R K+K + E + +K KEK++ + ++ EK +DK K
Sbjct: 391 KEKDREKERE-REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKE----------- 131
+++++K KE + S + K++K+ +PP+ + +
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509
Query: 132 -DIKPLKR-------PRDEDDADYKPKKIKTEDTKKEKK------RKLEEEEDGKLK--- 174
K +KR PR + D K +K + +++ ++ RK + DGK K
Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569
Query: 175 -------KPKNKDKDKKVPEPDNKKKKPKKEEEQ 201
K NK+ D V + + K P+ EE +
Sbjct: 570 NSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 68.9 bits (167), Expect = 2e-11
Identities = 51/191 (26%), Positives = 90/191 (47%), Gaps = 50/191 (26%)
Query: 13 EADFRLNDSHKHKDKHKDREHR---HKEHKKEKDREKSK---HSNSEHKDSEKKHKEKEK 66
++ R ++ + + KDR HK+ K ++R KS+ HS + KD+ +K KEKE+
Sbjct: 330 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 67 TKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYF 126
K KD E+ ++K ++++KE+ K + KE+E KD +D
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDR--------DKERE---------KDREKDK--- 429
Query: 127 VPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVP 186
E D + + +K +D KEK+++ ++E K + KD+ K++
Sbjct: 430 ---------------EKDREREREKEHEKDRDKEKEKEQDKE------KEREKDRSKEI- 467
Query: 187 EPDNKKKKPKK 197
D K+KK KK
Sbjct: 468 --DEKRKKDKK 476
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 82.4 bits (202), Expect = 1e-15
Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 12/205 (5%)
Query: 7 HNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEK---KHKE 63
HN S+ R HK + K RE R K + R+K K + + K+ E+ K +E
Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERR-KSRSRSHSRDKRKDTREKIKEKERVKEKDRE 280
Query: 64 KEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDD 123
KE+ + K+ EK + K+KDRDKE+ K+ + D + ++EKE+ + E E D
Sbjct: 281 KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH--EKDRDKEKEKEQD 338
Query: 124 GYFVPPKEDIKPLKRPRDEDDADYKPKKI-----KTEDTKKEKKRKLEEEEDGKLKKPKN 178
K+ K + R +D P + ++ + +E++R+ + K
Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398
Query: 179 -KDKDKKVPEPDNKKKKPKKEEEQK 202
K K + P P ++ KK KK E+++
Sbjct: 399 IKRKSSRSPSPRSRNKKDKKREKER 423
Score = 77.0 bits (188), Expect = 6e-14
Identities = 56/214 (26%), Positives = 99/214 (46%), Gaps = 36/214 (16%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K KD+ K+RE R KE +KEK+R K+K + E + +K KEK++ + ++ EK +DK K
Sbjct: 275 KEKDREKERE-REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKE----------- 131
+++++K KE + S + K++K+ +PP+ + +
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393
Query: 132 -DIKPLKR-------PRDEDDADYKPKKIKTEDTKKEKK------RKLEEEEDGKLK--- 174
K +KR PR + D K +K + +++ ++ RK + DGK K
Sbjct: 394 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 453
Query: 175 -------KPKNKDKDKKVPEPDNKKKKPKKEEEQ 201
K NK+ D V + + K P+ EE +
Sbjct: 454 NSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 68.9 bits (167), Expect = 2e-11
Identities = 51/191 (26%), Positives = 90/191 (47%), Gaps = 50/191 (26%)
Query: 13 EADFRLNDSHKHKDKHKDREHR---HKEHKKEKDREKSK---HSNSEHKDSEKKHKEKEK 66
++ R ++ + + KDR HK+ K ++R KS+ HS + KD+ +K KEKE+
Sbjct: 214 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 67 TKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYF 126
K KD E+ ++K ++++KE+ K + KE+E KD +D
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDR--------DKERE---------KDREKDK--- 313
Query: 127 VPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVP 186
E D + + +K +D KEK+++ ++E K + KD+ K++
Sbjct: 314 ---------------EKDREREREKEHEKDRDKEKEKEQDKE------KEREKDRSKEI- 351
Query: 187 EPDNKKKKPKK 197
D K+KK KK
Sbjct: 352 --DEKRKKDKK 360
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 81.3 bits (199), Expect = 3e-15
Identities = 48/219 (21%), Positives = 109/219 (49%), Gaps = 4/219 (1%)
Query: 8 NDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
+D Q E D + K +D+ + R+ + +KE +R + + +E + ++ K+K +
Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFV 127
+ +D E+ +D+ +++++E++ E+ + + ++E++ + + E + D
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 128 PPKEDIKPLKRPRDEDDADYKPKKIKTE-DTKKEKKRKLEEEEDGKLKKPKNKDKDKKVP 186
KE + R RD ++ +T+ + ++E R+ E + D K +++++D+K
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 187 EPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGP 225
+KK+ KKE ++K K EE+ E K K+ E P
Sbjct: 255 RKKERKKERKKERKEKKK---EEKRREDKKRKWGEGISP 290
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 79.7 bits (195), Expect = 9e-15
Identities = 49/182 (26%), Positives = 90/182 (49%), Gaps = 16/182 (8%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSE--KKHKEKEKTKHKDGSSEKHKDK 80
+ K + ++RE R +E +KE+ RE+ K + K E K+ + K K + K + K++
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 81 HKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPR 140
K + ++K++E K R + K KKE++ Q + + K KR +
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQ--------------RRERKRKKRRK 140
Query: 141 DEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEE 200
+ + K +K + + +K KKRK EE E + + K + K+++ E +KK+ KKE
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
Query: 201 QK 202
+K
Sbjct: 201 KK 202
Score = 78.2 bits (191), Expect = 3e-14
Identities = 47/180 (26%), Positives = 91/180 (50%), Gaps = 20/180 (11%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
+ ++K + RE KE KK K RE+ K + K+ EK+ KE+ + + + EK K + K
Sbjct: 48 REREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
R + +RK++K R + + K+ +E + K+ K KR ++
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRK--------------KKRRKERKREKER 153
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
+ K KK K E+ +K+++R +E +K + + K+++ + + KK++ KK+E +K
Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKE------RKKERERKERRERKKERKKERRKKKERKK 207
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/166 (28%), Positives = 88/166 (53%), Gaps = 12/166 (7%)
Query: 39 KKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKD-GSSEKHKDKHKDRDKEKRKEEKVRAS 97
++E +R+K E ++ EK+ +E+EK + ++ G EK K K ++R KE+ ++ K R
Sbjct: 31 QRESERKK------ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 98 GDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDT 157
K ++EKE + K E + G K K ++ R+ ++ + +K K
Sbjct: 85 -QRKERREKERRKRKKEKKKRERKQRGRRERKK---KKERKERERENKQRRERKRKKRRK 140
Query: 158 KKEKKRKLEEEEDGKL-KKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
KK +K + E+E GK +K K + K+++ + + +K+ KKE E+K
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
Score = 65.9 bits (159), Expect = 1e-10
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 20/185 (10%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
R + + + K + ++ + +E KE++R++ K+ EK+ KE+ + + + EK
Sbjct: 50 REKERKRERGKKEKKKRKKRERGKERERKR--------KEREKQRKERREKERRKRKKEK 101
Query: 77 HKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPL 136
K + K R + +RK++K R + + K+ +E + K E K + K
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
Query: 137 KRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPK 196
KR ++E ++ K E +KE+K++ E +E + KK + K++ KK ++KK +
Sbjct: 162 KRKKEE-------REKKRERNRKERKKERERKERRERKKERKKERRKK-----KERKKDR 209
Query: 197 KEEEQ 201
K + Q
Sbjct: 210 KTDRQ 214
Score = 53.1 bits (126), Expect = 9e-07
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 40/159 (25%)
Query: 55 KDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPP 114
++SE+K + +E+ K K +++ K+R +E+ K+EK K +K++E G
Sbjct: 32 RESERKKERREREKRK-------REREKERKRERGKKEK-------KKRKKRERG----- 72
Query: 115 QIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLK 174
K +R R E + K ++ K +K++K+K E ++ G+
Sbjct: 73 -------------------KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR-- 111
Query: 175 KPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPE 213
+ + K K++K E +NK+++ +K ++++ K +ER E
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKE-----KEKTKHKDGSSEKH 77
+ ++K + + R ++ +K+++REK + N + + E++ KE KE+ K + E+
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 78 KDKHKDRDKEKRKEEKVRAS 97
KD+ DR + + +R S
Sbjct: 207 KDRKTDRQTDSQVFRPLRES 226
Score = 43.9 bits (102), Expect = 6e-04
Identities = 19/76 (25%), Positives = 39/76 (51%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
+ K K ++RE + + ++KE+ +E+ + E K KK + K+K + KD +++ D
Sbjct: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
Query: 83 DRDKEKRKEEKVRASG 98
R + +V +G
Sbjct: 220 FRPLRESAFNRVTVTG 235
Score = 39.3 bits (90), Expect = 0.014
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 130 KEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPE-- 187
+E + +R E + K+ K E KKEKK++ ++ E GK ++ K K+++K+ E
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKR-KKRERGKERERKRKEREKQRKERR 90
Query: 188 --PDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHK 223
K+KK KK+ E+K + E + + K + E+K
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
Score = 34.7 bits (78), Expect = 0.34
Identities = 19/78 (24%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Query: 134 KPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKK-PKNKDKDKKVPEPDNKK 192
KP + E + + ++ + + +KE+KR+ ++E K KK + K++++K E + K+
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE-KQ 85
Query: 193 KKPKKEEEQKWKWWEEER 210
+K ++E+E++ + E+++
Sbjct: 86 RKERREKERRKRKKEKKK 103
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 79.3 bits (194), Expect = 1e-14
Identities = 51/191 (26%), Positives = 103/191 (53%), Gaps = 16/191 (8%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
+ K + ++RE R +E +KE+ RE+ K + K E+K +E+E+ K + E + + K
Sbjct: 58 ERKKERREREKRKREREKERKRERGK----KEKKGERKKEERERKKRRR-EKENKEGEEK 112
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
++ K+K K+E+ R S + K ++ KE + ++ +++ KE + ++ R+
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE----REKERERKERKKRER 168
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
K ++ K ++ K+ KKR E + K +K + + K+++ + + KKK+ +K+E QK
Sbjct: 169 KQVGEKEEERKEKERKERKKR----ERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Query: 203 ---WKWWEEER 210
W E+ER
Sbjct: 225 DRQTNWREKER 235
Score = 77.4 bits (189), Expect = 5e-14
Identities = 48/195 (24%), Positives = 102/195 (52%), Gaps = 5/195 (2%)
Query: 27 KHKDRE-HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRD 85
+ ++RE KE KKE++ E+ K K K+ +EKE+ + + +K + K ++R+
Sbjct: 39 REREREIETRKEGKKERESERKKERREREK--RKREREKERKRERGKKEKKGERKKEERE 96
Query: 86 KEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDA 145
++KR+ EK G+ K K++K+ K+ E + +E+ K +R ++E +
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 146 DYKPKKIKTEDTKK--EKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKW 203
+ + K+ K + K+ EK+ + +E+E + KK + K++K ++++ KKE ++K
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Query: 204 KWWEEERYPEGIKWK 218
+ +E + W+
Sbjct: 217 ERKKERQKDRQTNWR 231
Score = 47.8 bits (112), Expect = 4e-05
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 6/71 (8%)
Query: 29 KDREHRHKEHKKEKDREKS-KHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKD-----KHK 82
K+ E + KE K+ K RE++ K E + E++ ++KE+ K ++ E+ KD + K
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233
Query: 83 DRDKEKRKEEK 93
+R K +RKE K
Sbjct: 234 ERGKRERKERK 244
Score = 37.7 bits (86), Expect = 0.040
Identities = 52/233 (22%), Positives = 98/233 (42%), Gaps = 30/233 (12%)
Query: 134 KPLKRPRDEDDADYKPKKIKT-----EDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEP 188
KP +P + + + ++I+T ++ + E+K++ E E K ++ K + +++ E
Sbjct: 27 KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 189 DNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGK--V 246
++KK ++E +++ + E + E K K E K E + +GK
Sbjct: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKK------------ERGRTSKEGKERE 134
Query: 247 MKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMS 306
K K EE K + E KE RK K RK++ +E+ K
Sbjct: 135 RKEERKREERKERERKKEERE---KERERKERKKRERKQVGEKEEERKEKERK------- 184
Query: 307 QYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPG 359
K + RK+ KE + K + E +K K+ + K+R N++ + G
Sbjct: 185 -ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Score = 35.4 bits (80), Expect = 0.20
Identities = 16/74 (21%), Positives = 34/74 (45%)
Query: 3 GDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHK 62
G+ + E R K++ K+RE + + +K++ ++K + KD + +
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR 231
Query: 63 EKEKTKHKDGSSEK 76
EKE+ K + +K
Sbjct: 232 EKERGKRERKERKK 245
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 77.8 bits (190), Expect = 4e-14
Identities = 41/204 (20%), Positives = 108/204 (52%), Gaps = 23/204 (11%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
R + + +D+ +DR+ R KE +++ DR++ + + + + K+ +++E+ + ++ + ++
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 77 HKDKHKDR----------DKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYF 126
+++ ++R D+EK +E K + + ++ ++ G Q + E E +
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE--- 374
Query: 127 VPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVP 186
+E + R R+E + D + D +KE++R+ E++ DG+ + K ++++K
Sbjct: 375 ---RERDRQSAREREERERD------RDRDRQKERERQTEKDRDGQRETEKQREREKD-R 424
Query: 187 EPDNKKKKPKKEEEQKWKWWEEER 210
E + +++ ++ E+QK + + ER
Sbjct: 425 ESERGRERGREREKQKGRERDRER 448
Score = 72.4 bits (176), Expect = 1e-12
Identities = 47/222 (21%), Positives = 109/222 (49%), Gaps = 16/222 (7%)
Query: 3 GDHLHNDSQIEADFRLNDSHKHKDKHKDREH-RHKEHKKEKDREKSKHSNSEHKDSEKKH 61
G D Q E + R D+ K +++ DRE R E ++K+RE+ K+ ++
Sbjct: 138 GRDRQTDGQRERE-RQRDAEKERERQTDRERQRQTERNRQKEREREKN--------RQER 188
Query: 62 KEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPE 121
+E+E+ + K+ +E D+H +R +E+ +E + + K + ++E + + E +
Sbjct: 189 RERERQREKENKTE---DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245
Query: 122 DDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDK 181
+ +E + +R R+ D + ++ K + + ++KR+ E D + ++ + + +
Sbjct: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Query: 182 DKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHK 223
+++ N+K++ ++E E++ E +R E + K E K
Sbjct: 306 ERERERERNRKRERERERERE---RERQRETERDREKERERK 344
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/198 (20%), Positives = 98/198 (49%), Gaps = 18/198 (9%)
Query: 17 RLNDSHKHKDKHKDRE-HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSE 75
R + + KD+H+ R+ HR ++ +EK+RE+ + + ++++++KE+ + + E
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 76 KHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKP 135
+ +D+ D +E+ ++ + + +E++ Q + E E + +++ +
Sbjct: 137 RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN------RQERRE 190
Query: 136 LKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKP 195
+R R++++ KTED E+ R+ E E + + + + + D+ E D ++K
Sbjct: 191 RERQREKEN--------KTEDRHSERGRERERERETETETERKRQTDR---ERDRQRKTE 239
Query: 196 KKEEEQKWKWWEEERYPE 213
++ E+Q + ER E
Sbjct: 240 REREKQAERERASERETE 257
Score = 59.7 bits (143), Expect = 1e-08
Identities = 44/199 (22%), Positives = 95/199 (47%), Gaps = 17/199 (8%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHK-DSEKKHKEKEKT---KHKDGSSE 75
+ + ++K E RH E +E++RE+ + +E K ++++ + KT + K E
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 76 KHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKP 135
+ ++ +RDKE+ +E D + +KE+E Q + E + +E +
Sbjct: 250 RASERETERDKERERERDRDRDRDRR-QKERERQTDRKRQRRTERD--------RETERK 300
Query: 136 LKRPRD-EDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKK 194
+R R+ E + + K+ + + ++E++R+ E E D ++ + + K K+ E D ++ +
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERD---REKERERKRKRQTEMDRERNR 357
Query: 195 PKKEEEQKWKWWEEERYPE 213
E ++ E ER E
Sbjct: 358 QTGREGRRQAERERERERE 376
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/206 (17%), Positives = 95/206 (46%), Gaps = 9/206 (4%)
Query: 17 RLNDSHKHKDKHKDREH-----RHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKD 71
R D K +++ DRE + + +KE++RE + +E+E+ + +
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
Query: 72 GSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKE 131
E+ D+ + R E+ ++++ + + ++E+E + +D + G +
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216
Query: 132 DIK---PLKRPRD-EDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPE 187
+ + KR D E D K ++ + + ++E+ + E E D + ++ +++D+D+ +
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 188 PDNKKKKPKKEEEQKWKWWEEERYPE 213
+ +++ +K + + + E ER E
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRE 302
Score = 53.5 bits (127), Expect = 7e-07
Identities = 22/100 (22%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
R + + +D+ RE +E +++DR+K + +E ++ EK++ + KD SE+
Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
Query: 77 HKDKHKDRDKEKRKEEKVRASGDAKIKKEKENG--FSSPP 114
+++ ++R+K+K +E D + ++++ + +PP
Sbjct: 429 GRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPP 468
Score = 48.1 bits (113), Expect = 3e-05
Identities = 39/206 (18%), Positives = 94/206 (45%), Gaps = 27/206 (13%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDG---- 72
R + ++ +++ ++RE R +E ++E +R++ K + K + +E+ + ++G
Sbjct: 309 RERERNRKRERERERE-RERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 73 SSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKED 132
E+ +++ +DR + +EE+ R D +KE+E + E + DG +E
Sbjct: 368 ERERERERERDRQSAREREERER-DRDRDRQKERER--------QTEKDRDG----QRET 414
Query: 133 IKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKK 192
K +R +D +++ ++ + + +K ++R E + D + + + + P P +
Sbjct: 415 EKQREREKDR-ESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTAR 473
Query: 193 KKPKKEEEQKWKWWEEERYPEGIKWK 218
+ + R GI+WK
Sbjct: 474 SGVVQS--------DPNRPTRGIRWK 491
Score = 34.7 bits (78), Expect = 0.34
Identities = 20/94 (21%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
Query: 136 LKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKK-----VPEPDN 190
L + + D D + + + E ++ +KR+ E E D K ++ + KD+ +K + D
Sbjct: 42 LGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDR 101
Query: 191 KKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKG 224
+K++ ++ + ++ + E+ER + + + E +G
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREG 135
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 77.0 bits (188), Expect = 6e-14
Identities = 69/222 (31%), Positives = 96/222 (43%), Gaps = 28/222 (12%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHR---HKEHKK-EKDREKSKHSNSEHKDSEKKHKEK 64
DS+ E DS K KD K +E + K+ KK +KD EK K S +E +D + K+
Sbjct: 129 DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKD 188
Query: 65 EKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDD- 123
K KD S K KD + + EK EK G KK K++ DE +D+
Sbjct: 189 NKKDKKD--SNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDED 246
Query: 124 --------GYFVPPKEDIKPLKRPR------------DEDDADYKPKKIKTEDTKKEKKR 163
K+D K +K+ + +DD + KK T+D KK K+
Sbjct: 247 GKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKK 306
Query: 164 KLEEEE-DGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWK 204
E+E D K KN KD K N KK KK+ ++K K
Sbjct: 307 DTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
Score = 57.8 bits (138), Expect = 4e-08
Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 17/163 (10%)
Query: 55 KDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKI-KKEKENGFSSP 113
K E K +K+ T + + KD K +D EK KEEK+ A D+K KK+ E G S
Sbjct: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
Query: 114 PQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKR---------- 163
+ +D E G K+D K + +D K +D+KK KK
Sbjct: 176 TESED--EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
Query: 164 ----KLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
K +E++D KK NK + K + D K+ K K++++K
Sbjct: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK 276
Score = 35.4 bits (80), Expect = 0.20
Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
Query: 3 GDHLHNDSQIEADFRLNDSHKHKDKHKDREHRH---KEHKKEKDREKSKHSNSEHKDSEK 59
GD + + + + K K D + + KE KK+ ++ K + KD+EK
Sbjct: 254 GDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAK---KDTEK 310
Query: 60 KHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEK 93
+ + +K K+ + KD K+ K+++K+ K
Sbjct: 311 ESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAK 344
Score = 33.1 bits (74), Expect = 0.99
Identities = 62/270 (22%), Positives = 103/270 (38%), Gaps = 27/270 (10%)
Query: 86 KEKRKEEKVRASGDAKIKKEKENGFSSPP--------QIKDEPEDDGYFVPPKEDIKPLK 137
K + K ++R + + I +E+ G P +I + P Y ++ +KP +
Sbjct: 46 KRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSV--YLAARRQPLKPTR 103
Query: 138 RPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD----KDKKVPEPDNKKK 193
+ A KK + + T+K+ E + GK K KD K++K+ + KK
Sbjct: 104 TVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKK 163
Query: 194 KPKKEEEQKWKWWEEERYPEGIKW-----KFLEHKGPVFAPPYE-----PLPENVKFYYD 243
K E+ K E E G K K +KG A E ++ K D
Sbjct: 164 GKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKD 223
Query: 244 GKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFT 303
K K A E+ A E K+ + + KD +K+ E K + K T
Sbjct: 224 SK--KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD-AKEIKKGKKDKKKPSST 280
Query: 304 QMSQYFKAQTEARKQMSKEEKLKIKEENEK 333
+ E++K +K+ K K++ EK
Sbjct: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEK 310
Score = 30.4 bits (67), Expect = 6.4
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 651 IDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVE--SKKKAVQRLEEQLMKLEVQATDR 708
I+ KE+ DA++D K K DA+ KD+ T+ E KK ++ ++ K + AT+
Sbjct: 147 IEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATES 206
Query: 709 EENK 712
E K
Sbjct: 207 EGEK 210
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 75.5 bits (184), Expect = 2e-13
Identities = 63/324 (19%), Positives = 143/324 (44%), Gaps = 31/324 (9%)
Query: 18 LNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKH 77
+ + +++ ++RE +E ++E++RE+ + E + ++ +++++TK +D ++
Sbjct: 305 IEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE 364
Query: 78 KDKHKDRDKEK-------RKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPK 130
+D+ +DR++ R EK R + + ++E+E + + E E + +
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSR-DRERERERERERERERERERERERERERERERER 423
Query: 131 EDIKPLKRPRDEDDAD-YKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPD 189
E K KR R+ED+ D Y+ +K+ +RKL E+E ++ KN + ++ +
Sbjct: 424 EREKDKKRDREEDEEDAYERRKL---------ERKLREKEAAYQERLKNWEIRERKKTRE 474
Query: 190 NKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKL 249
+K+ ++EE ++ E +R E F Y+ ++ K+Y + K
Sbjct: 475 YEKEAEREEERRREMAKEAKRLKE-------------FLEDYDDDRDDPKYYRGSALQKR 521
Query: 250 SPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYF 309
E+ + E E R+ + + E + + + Q+ Q
Sbjct: 522 LRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEP 581
Query: 310 KAQTEARKQMSKEEKLKIKEENEK 333
+++ E ++ KEEK + E E+
Sbjct: 582 ESEEEEEEKQEKEEKREEPMEEEE 605
Score = 69.7 bits (169), Expect = 1e-11
Identities = 55/247 (22%), Positives = 120/247 (48%), Gaps = 32/247 (12%)
Query: 17 RLNDSHKHKDKHKDREH-RHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKD---- 71
R D + ++K +DRE R +E ++E++RE+ + E + ++ +E+EK K +D
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436
Query: 72 --GSSEKHKDKHKDRDKEKRKEEKVR----------ASGDAKIKKEKENGFSSPPQIK-- 117
+ E+ K + K R+KE +E+++ + + ++E+E + K
Sbjct: 437 EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496
Query: 118 -------DEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEE--- 167
D+ DD + K L+ E +AD + +K + E+ ++ ++R L E
Sbjct: 497 KEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHP 556
Query: 168 EEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVF 227
+ D +L++ + + + ++ P+ K++P+ EEE++ K +EE+ E ++ + + P
Sbjct: 557 DPDAELQRMEQEAERRRQPQ---IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCL 613
Query: 228 APPYEPL 234
P P+
Sbjct: 614 KPTLRPI 620
Score = 59.7 bits (143), Expect = 1e-08
Identities = 66/350 (18%), Positives = 142/350 (40%), Gaps = 50/350 (14%)
Query: 10 SQIEADFRLNDSHKHKDKHKDREHRHKE--------------------HKKEKDREKSKH 49
S++ A + +DSH K K + +E + +E R+
Sbjct: 220 SELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISR 279
Query: 50 SNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENG 109
S+ +D+ KK +E++ K K+ ++ K+R + +R+ E+ R + + ++E+E
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKE-----RQEIEKERRERERERERERERRERERERERERE 334
Query: 110 FSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDED-DADYKPKKIKTEDTKKEKKRKLEEE 168
+ + E E D KE + R RD D D + + K +EK R E E
Sbjct: 335 REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERE 394
Query: 169 EDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFA 228
+ + ++ + ++++++ ++++ ++E E+ K EE + + + LE K
Sbjct: 395 REREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454
Query: 229 PPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTN 288
Y+ +N + K + +AE ++ R+EM
Sbjct: 455 AAYQERLKNWEIRERKKTREYEKEAERE-----------------------EERRREMAK 491
Query: 289 EEKNIITNLSKCDFTQMS-QYFKAQTEARKQMSKEEKLKIKEENEKLLKE 337
E K + L D + +Y++ ++ +E++++ E + K KE
Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE 541
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 71.6 bits (174), Expect = 3e-12
Identities = 45/200 (22%), Positives = 99/200 (49%), Gaps = 30/200 (15%)
Query: 8 NDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
N ++ E R D H+ +D+ DRE + +E +KE+DR++ + +E + ++ +++++
Sbjct: 29 NQTERENRHRQRDRHRERDRQTDRE-KERERQKERDRQRQRERETERETERQRERQRQRE 87
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFV 127
+ + + +++ KDRD+E+++E D ++ ++ G Q + E + +
Sbjct: 88 RKR----QTDRERDKDRDRERKRET------DRNRERNRKGGRERDKQTERERDRERERQ 137
Query: 128 PPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPE 187
+E + +R R + + + + E+ KKE+K K + K++K
Sbjct: 138 RQRERERQRQRERKRETDRERQRWAEREERKKERK--------------KERKKERK--- 180
Query: 188 PDNKKKKPKKEEEQKWKWWE 207
KKK+ K+ E++K KW E
Sbjct: 181 --EKKKEEKRREDKKRKWGE 198
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/197 (17%), Positives = 93/197 (47%), Gaps = 16/197 (8%)
Query: 34 RHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEK 93
R +E K+E DR K +D +++ + + + +++ ++H+++ + D+EK +E +
Sbjct: 3 RQRERKRETDRGKE---TERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
Query: 94 VRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDED---------- 143
+ ++E E + + + E ++ + +R R+ D
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 144 -DADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKK--KKPKKEEE 200
+ D + ++ + + +++++R+ E + + K+ ++++ + + KK KK +K+E
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 201 QKWKWWEEERYPEGIKW 217
++ K E+ R + KW
Sbjct: 180 KEKKKEEKRREDKKRKW 196
Score = 35.4 bits (80), Expect = 0.20
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSS 74
R ++ + + + +RE R KE KKE+ +E+ + K E+K +E +K K +G S
Sbjct: 150 RKRETDRERQRWAEREERKKERKKERKKERKE------KKKEEKRREDKKRKWGEGIS 201
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 70.1 bits (170), Expect = 7e-12
Identities = 67/340 (19%), Positives = 170/340 (50%), Gaps = 38/340 (11%)
Query: 29 KDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKH-KDRDKE 87
++ E R +E K K EK ++ E K +E+E+ + + ++K ++++KE
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 88 KRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPE-----DDGYFVPPKEDIKPLKRPRDE 142
R+++K+R + ++++++E + +++++ E ++ + K+ + ++ RD+
Sbjct: 299 LREQKKLREQ-EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357
Query: 143 DDADY-KPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPD----NKKKKPKK 197
++ + + ++++ ++ + ++ K+ E+E+ ++ + ++++KK+ E + +++K +K
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 198 EEEQKW----KWWEEERYPEGIK--W---KFLEHKGPVFAPPYEPLPENVKFYYDGKVM- 247
+EE W K W+++R PE + W K E + ++ E + + + + K M
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMW 476
Query: 248 ---KLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWR----KEMTNEEKNIITNLSKC 300
K+ + +++ KM D E + + + +D R +E E+K + K
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK- 535
Query: 301 DFTQMSQYFKAQTEARKQMSKEEKLKIKE---ENEKLLKE 337
M + K Q + +K +EEK++ +E E EK ++E
Sbjct: 536 ----MREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Score = 69.3 bits (168), Expect = 1e-11
Identities = 66/322 (20%), Positives = 154/322 (47%), Gaps = 31/322 (9%)
Query: 26 DKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT-KHKDGSSEKHKD----- 79
++ +++E R +E +K ++E+ ++ EKK +E+E+T + ++ +K ++
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 80 KHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRP 139
+ K+ +++ E+K + K+++++E + +I+D+ E G K+ + K
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG---QEKKMWRQEKMR 482
Query: 140 RDEDDADYKPKKIKTEDTKK-EKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKE 198
ED + +K++ ++ K +++ ++ E+++ +K + + KK+ + + K ++ KK
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 199 EEQKWKWW-EEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVA 257
+EQ+ K W +EE+ E + + E K E + E + K+ + E++
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKK---MREEEEMMREQEE--------KMQEQEEKMR 591
Query: 258 TFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARK 317
KM + E E ++ K W +E E+ + + + Q K Q + K
Sbjct: 592 EQEEKMWEQE----EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 318 QMSKEEKL-----KIKEENEKL 334
+EEK+ K++E+ EK+
Sbjct: 648 MWEQEEKMREQEEKMREQEEKM 669
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/205 (18%), Positives = 109/205 (53%), Gaps = 12/205 (5%)
Query: 13 EADFRLNDSHKHKDKHK---DREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKE-KTK 68
E D RL + + + K +E + +E KK +++EK E E++ +E+E K +
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570
Query: 69 HKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVP 128
++ + ++K ++++++ R++E+ + K+++++E + ++ ++ E+D
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED----- 625
Query: 129 PKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEED---GKLKKPKNKDKDKKV 185
++ + + ++E + + K + E+ +E++ K+ E+E+ G+ +K + +++ +
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 186 PEPDNKKKKPKKEEEQKWKWWEEER 210
E ++++ K +++ W +EE+
Sbjct: 686 QEEKMREQEEKMRGQEEKMWGQEEK 710
Score = 60.5 bits (145), Expect = 6e-09
Identities = 58/351 (16%), Positives = 171/351 (48%), Gaps = 23/351 (6%)
Query: 11 QIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHK 70
Q E +++ + K+K ++E ++ +K ++E+ E EKK +EK + +
Sbjct: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 71 DGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPK 130
+ + ++K +D++++ +E+ D ++++++E + E
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE----------- 533
Query: 131 EDIKPLKRPRDEDDADY-KPKKIKTEDTKKEKKRKL-EEEEDGKLKKPKNKDKDKKVPEP 188
E ++ K+ ++++ + + +K++ E+ +E+++K+ EEEE + ++ K +++++K+ E
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 189 DNK--KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKV 246
+ K +++ K +E+++ W +EE+ E + ++ + + E + E + ++ +
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE-QE 652
Query: 247 MKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMS 306
K+ + E++ KM E +E ++ + ++M +E+ + K +
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMRE--QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 307 QYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEP 357
+ + + ++ +E++ +I+++ EK+ + + H+ER + + P
Sbjct: 711 MWGQEEKMWGQEEMREKEERIRDQKEKMQER-----LPEHEERCSEPCLPP 756
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/222 (20%), Positives = 109/222 (49%), Gaps = 11/222 (4%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTK 68
D E + ++ D + K D+E R E + E+ REK + + K +++ K +E+ K
Sbjct: 486 DQMWEQEEKMRDQEQ---KMWDQEERMWE-QDERLREKEERMREQKKMWQQEEKMREEKK 541
Query: 69 HKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVP 128
++ + + K R++E+ +E + + + ++ +E+E + E E+ +
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 129 PKEDIKPLKRPRDED---DADYKPKKIKTEDTKKEKKRKLEEEEDGKL-KKPKNKDKDKK 184
K + K E+ + + + K + E+ E++ K++E+E+ ++ K +++++K
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Query: 185 VPEPDNK---KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHK 223
+ E + K +++ +E+E+K + EE+ + K + E K
Sbjct: 662 MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 70.1 bits (170), Expect = 7e-12
Identities = 45/199 (22%), Positives = 102/199 (51%), Gaps = 20/199 (10%)
Query: 17 RLNDSHKHKDKHKDREH-RHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSE 75
R + + +++ +DR+H R +E ++E+DREK + E ++ E++ +E+E+ + ++ E
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERE-RERERERERERERE 775
Query: 76 KHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKP 135
+ +++ K+R++++ E+K + D + K+E+ +D DG+ ++ K
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIR--------EDRNPRDGH-----DERKS 822
Query: 136 LKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKP 195
KR R+E P ++ ++E + G K K++ + V +++ P
Sbjct: 823 KKRYRNEG----SPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSP 878
Query: 196 KK-EEEQKWKWWEEERYPE 213
E+++ +W EE+R PE
Sbjct: 879 SHLTEDRQGRWKEEDRKPE 897
Score = 61.2 bits (147), Expect = 3e-09
Identities = 45/207 (21%), Positives = 92/207 (44%), Gaps = 40/207 (19%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
R + + +D+ K+RE +E ++E++RE+ + E + + ++KE+ + +D
Sbjct: 735 RERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRD----- 789
Query: 77 HKDKHKDRDKEKRKEEKVR-------ASGDAKIKKEKEN-GFSSPPQI-----KDEPEDD 123
+DK K RD + K E++R + K KK N G SP Q + P+ D
Sbjct: 790 WEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 849
Query: 124 GYFVPPKEDIKPLKRPRDEDDADYK----PKKIKTEDTKKEKKRKLEEEEDGKLK----K 175
Y DD + K + ++ ++++ L E+ G+ K K
Sbjct: 850 AY--------------NSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 895
Query: 176 PKNKDKDKKVPEPDNKKKKPKKEEEQK 202
P+ K+ ++ E + K+K +++++
Sbjct: 896 PERKESSRRYEEQELKEKVSSVDKQRE 922
Score = 60.8 bits (146), Expect = 4e-09
Identities = 37/226 (16%), Positives = 101/226 (44%), Gaps = 15/226 (6%)
Query: 2 SGDHLHNDSQIEADFRLNDSHKHKDKHKDR-----EHRHKEHKKEKDREKSKHSNSE--- 53
S + H+ + + + D + +D E RH E + +RE+ + +S
Sbjct: 588 SNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH 647
Query: 54 -------HKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEK 106
+D ++ + ++ + + +D+ ++RD+E+ +E + + + ++E
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKEREL 707
Query: 107 ENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLE 166
E + + + E E D ++ + +R R+ D + ++ + + ++E++R+ E
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767
Query: 167 EEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYP 212
E + + ++ + +DK+++ K K + + +K + E+R P
Sbjct: 768 RERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813
Score = 50.4 bits (119), Expect = 6e-06
Identities = 54/225 (24%), Positives = 96/225 (42%), Gaps = 29/225 (12%)
Query: 29 KDREHRHKEHKKEKDREKSKHSNSEHKDSEKKH---KEKEKTKHKDGSSEKHKD---KHK 82
+DR+ R KE ++ +R++S E + EK K++E+T+ + S + +D H+
Sbjct: 883 EDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 83 DRDKEK----RKEEKVRASGDAK-IKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIK--- 134
D+E E K +A K IKK+KE+ + +DG PK+ K
Sbjct: 943 SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002
Query: 135 -PLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKK- 192
KR + + D+D I E+ ++ K+K + P K++ V + K
Sbjct: 1003 IEKKRKKSKGDSD-----ISDEEAAQQSKKKRGP------RTPPITTKEELVEMCNGKNG 1051
Query: 193 --KKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLP 235
+ +K+E+ + W +E P+ + EH P P P
Sbjct: 1052 ILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSP 1096
Score = 50.1 bits (118), Expect = 8e-06
Identities = 56/251 (22%), Positives = 109/251 (43%), Gaps = 42/251 (16%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDS------EKKHKEKEK 66
E + R + + +++ ++RE R +E +E+D+E+ + + E KD EK+ + +E
Sbjct: 752 EREERERERERERERERERE-RERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810
Query: 67 TKHKDGSSEKHKDKH-------KDRDKEKRKEE-----KVRASGDAKIKKEK-------- 106
+DG E+ K R KR+ E SGD K +K +
Sbjct: 811 RNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870
Query: 107 -ENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKL 165
E+ SP + ++ + +ED KP R E Y+ +++K + + +K+R+
Sbjct: 871 QESRSLSPSHLTEDRQGRW----KEEDRKP---ERKESSRRYEEQELKEKVSSVDKQREQ 923
Query: 166 EE-EEDGKLKKP------KNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWK 218
E E +++ +++D++ D KKK K +++ K E++ E +
Sbjct: 924 TEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIE 983
Query: 219 FLEHKGPVFAP 229
G VF+P
Sbjct: 984 TTSEDGQVFSP 994
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/203 (18%), Positives = 96/203 (47%), Gaps = 23/203 (11%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKEKD-REKSKHSNSEHKDSEKKHKEKEKTKHKD 71
+ D ++S+ H + ++ E+D R++++ S+ E + E+ ++ + +
Sbjct: 582 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 641
Query: 72 GSSEKHKDKHKDRDKEKRKEEK-VRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPK 130
S +H+ ++ + ++++R+EE+ V D + ++ +E E E D +
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERD--------RERERD------R 687
Query: 131 EDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDN 190
E + +R RD + + K + ++E+ R+ E E + + + +++D+D
Sbjct: 688 ERERERERERDRE-------REKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 191 KKKKPKKEEEQKWKWWEEERYPE 213
+++ +KE E++ + E ER E
Sbjct: 741 RERDREKEREREREERERERERE 763
Score = 43.9 bits (102), Expect = 6e-04
Identities = 41/215 (19%), Positives = 85/215 (39%), Gaps = 33/215 (15%)
Query: 21 SHKHKDKHKDRE------HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSS 74
S H +H+ RE R K+ ++E++ E+ + S+ +H+D + +++ +D
Sbjct: 407 SQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRD 466
Query: 75 EKH-KDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDI 133
+ +D RD + ++ S D K ++ + S D + +G KED
Sbjct: 467 RRELRDSRDMRDSREMRD----YSRDTKESRDPRDS-RSTRDAHDYRDREGRDTHRKEDT 521
Query: 134 KPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKK 193
P E+ Y ++ E ++ E + + E +++ + +VPE K
Sbjct: 522 YP------EESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGS 575
Query: 194 KPKKEE---------------EQKWKWWEEERYPE 213
+ + E + + E +RYPE
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPE 610
Score = 41.2 bits (95), Expect = 0.004
Identities = 37/181 (20%), Positives = 77/181 (42%), Gaps = 12/181 (6%)
Query: 29 KDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDK---HKDRD 85
+D +HR +K S SN H + + H+ G + + + RD
Sbjct: 1176 EDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSA-HRSGDDQSGRKRVLHSGSRD 1234
Query: 86 KEKRKEEKVRASGDAKIKKEK--ENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDED 143
+EK K ++ ++I + K E S+ +D P+ D + R D
Sbjct: 1235 REKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFD 1294
Query: 144 DADYKPKKIKTE-DTKKEKKRK----LEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKE 198
D ++ + E D ++E++R+ E + D P+N+D+D ++ E + ++++ K+
Sbjct: 1295 SRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRD-RLRERERERERDKRR 1353
Query: 199 E 199
+
Sbjct: 1354 D 1354
Score = 40.4 bits (93), Expect = 0.006
Identities = 50/251 (19%), Positives = 104/251 (41%), Gaps = 60/251 (23%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSK-HSNSEHKDSEKKHKEKEKT----------- 67
D+H ++D+ HR ++ E+ R + H E +E +++ + ++
Sbjct: 503 DAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGR 562
Query: 68 ----------KHKDGSSEKHKDKH------------------KDRDKEKRKEEKVRASG- 98
K GS D H +DR E+ ++ R S
Sbjct: 563 SRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSF 622
Query: 99 -------DAKIKKEKENGFSSPPQIK---DEPEDDGY-------FVPPKEDIKPLKRPRD 141
D + +E++ SSP + + DE E D V + D + +R R+
Sbjct: 623 ERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRE 682
Query: 142 -EDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDK-KVPEPDNKKKKPKKEE 199
E D + + ++ + D ++EK+R+LE E + ++ + K++D+ + + D+ +++ ++ E
Sbjct: 683 RERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERE 742
Query: 200 EQKWKWWEEER 210
+ K E ER
Sbjct: 743 RDREKERERER 753
Score = 40.0 bits (92), Expect = 0.008
Identities = 41/224 (18%), Positives = 96/224 (42%), Gaps = 28/224 (12%)
Query: 2 SGDHLHNDSQIEADFRLND---SHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSE 58
S H S E+D +++ S +D+ ++R+ + ++E++R ++ + +
Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK 1329
Query: 59 KKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPP---- 114
+ +++ + ++ E+ +DK +D D+E +E + S + ++++ F S
Sbjct: 1330 DWPRNRDRDRLRERERERERDKRRDLDRE--RERLISDSVERDRDRDRDRTFESSQIESV 1387
Query: 115 ---QIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEED- 170
+ K E E + D L + R D D + E K E+ LE +D
Sbjct: 1388 KRCEAKLEGEHERDLESTSRDSLALDKER--MDKDLGSVQGFEETNKSERTESLEAGDDE 1445
Query: 171 -------------GKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQ 201
G+ +P + D+ ++ D +K++ +++EE+
Sbjct: 1446 SKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEK 1489
Score = 35.4 bits (80), Expect = 0.20
Identities = 35/197 (17%), Positives = 80/197 (40%), Gaps = 8/197 (4%)
Query: 42 KDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAK 101
++R K+K + + + ++ +E K+ S +H++K + K +E+ S +
Sbjct: 86 RERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREK----EDIKITKERTPESEEEN 141
Query: 102 IKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEK 161
++ E S I + + ++ I+ ++++ + + + I ++ E
Sbjct: 142 VEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEV 201
Query: 162 KRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLE 221
R + L+K K K P+ + KK +K +++R K +
Sbjct: 202 VRS-KLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQR---NSKTNQSK 257
Query: 222 HKGPVFAPPYEPLPENV 238
KGP P P+PE++
Sbjct: 258 KKGPRTPSPPPPIPEDI 274
Score = 33.1 bits (74), Expect = 0.99
Identities = 30/186 (16%), Positives = 68/186 (36%), Gaps = 14/186 (7%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
+ + +K KD+ +++ K+ ++ +R++ K +H ++H SS+
Sbjct: 279 KYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQS 338
Query: 77 HKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPL 136
+ +RK + + P + P P+ P
Sbjct: 339 GSSIQRHSPSPRRKRTP---------SPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSP- 388
Query: 137 KRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD-KDKKVPEPDNKKKKP 195
PR K + E T + R+ E ED + K+ + KD ++++ E D +
Sbjct: 389 --PRHRSPMREKGRH-DHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445
Query: 196 KKEEEQ 201
+++ +
Sbjct: 446 HRDDRE 451
Score = 32.7 bits (73), Expect = 1.3
Identities = 30/127 (23%), Positives = 60/127 (47%), Gaps = 17/127 (13%)
Query: 9 DSQIEADFRLNDSHK--HKDKHKDREHRHKEHKKE-KDREKSKHSNSEHKDSEKKHKEKE 65
DS+ E ++ + S H+D + R+ R + ++ +DR + + S E + ++
Sbjct: 429 DSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRD 488
Query: 66 KTKHKDG-SSEKHKDKHKDRDKE----KRKE----EKVRASGDAKIKKEKENGFSSPPQI 116
+ +D S +D H RD+E RKE E+ R+ G +++E SS +I
Sbjct: 489 TKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREE-----SSRTEI 543
Query: 117 KDEPEDD 123
++E ++
Sbjct: 544 RNESRNE 550
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 69.3 bits (168), Expect = 1e-11
Identities = 53/209 (25%), Positives = 106/209 (50%), Gaps = 22/209 (10%)
Query: 17 RLNDSHKHKDKHKDRE-HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSE 75
R D + KDR+ HR ++ ++ R +S+ S S+ + E++HKE+E+ K +D
Sbjct: 30 RDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSR-SRSKSAERERRHKERERDKERD---R 85
Query: 76 KHKDKHKDRDKEKRKEEKVRAS------GDAKIKKEKENGFSSPPQIKDEPEDDGYFVPP 129
KD+ +D+D +R +++ R+S D K +K++++ KDE ++ G P
Sbjct: 86 NKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSK-------KDEEDEHGDKKPK 138
Query: 130 KEDI---KPLKRPRDEDDADYKPKKI-KTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
+ + + L + + E++A+ KPK + K E + KR+ +E E+ + + + K K+
Sbjct: 139 AQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQF 198
Query: 186 PEPDNKKKKPKKEEEQKWKWWEEERYPEG 214
+ K + +E E++ + ER G
Sbjct: 199 QDLGRKMLEDPQERERRERRERMERETNG 227
Score = 65.9 bits (159), Expect = 1e-10
Identities = 50/205 (24%), Positives = 106/205 (51%), Gaps = 18/205 (8%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
+ + K +RE RHKE +++K+R+++K KD ++ K+++++ G + K + K
Sbjct: 62 RSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSR-K 120
Query: 83 DRDKEKRKEEKVRASGDAKIKKE--KENGFSSPPQIKDEPEDDGYFVPPKE-DIKPLKRP 139
DRD +K +E++ GD K K + + + ++E E F+ E + + LKR
Sbjct: 121 DRDSKKDEEDE---HGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRR 177
Query: 140 RDEDDADYKPKKIKTEDTKKEK------KRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKK 193
+ E + + +++ E+ KK K ++ LE+ ++ + ++ + + + + D + +
Sbjct: 178 QQEVE---ERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGR 234
Query: 194 KPKKEEEQKWKWWE--EERYPEGIK 216
+ +EE+ K K +ERY GIK
Sbjct: 235 QKIREEKDKSKELHAIKERYLGGIK 259
Score = 59.7 bits (143), Expect = 1e-08
Identities = 43/193 (22%), Positives = 89/193 (46%), Gaps = 14/193 (7%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K +D +E R + +++R++ + S K+H+ +++ + GS + + + K
Sbjct: 9 KDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDR--RRGGSRSRSRSRSK 66
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDD-----GYFVPPKEDIKPLK 137
++E+R +E+ R + KK+++ + KD G ++D + K
Sbjct: 67 SAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKD-RDSK 125
Query: 138 RPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKK 197
+ +++ D KPK + K+K EEE + KPK K ++ E K+ ++
Sbjct: 126 KDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEA---KPKFLSKAEREAE---ALKRRQQ 179
Query: 198 EEEQKWKWWEEER 210
E E++ + EEER
Sbjct: 180 EVEERQRMLEEER 192
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/183 (25%), Positives = 84/183 (45%), Gaps = 22/183 (12%)
Query: 41 EKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEK-----RKEEKVR 95
+KDR+ S S E K S +E+++ + + S K + +H+ RD+ + R + +
Sbjct: 8 KKDRDASP-SKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 96 ASGDAKIKKEKENGFSSPPQIKDEPED-DGYFVPPKEDIKPLKRPRDEDDADYKPKKIKT 154
++ + KE+E KD D DG+ +R +D + P + K
Sbjct: 67 SAERERRHKERERDKERDRNKKDRDRDKDGH-----------RRDKDRKRSSLSPGRGKD 115
Query: 155 EDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEE-ERYPE 213
++K++ K +EE++ KKPK + E KKK ++E E K K+ + ER E
Sbjct: 116 FKSRKDRDSKKDEEDEHGDKKPKAQPLSL---EELLAKKKAEEEAEAKPKFLSKAEREAE 172
Query: 214 GIK 216
+K
Sbjct: 173 ALK 175
Score = 39.7 bits (91), Expect = 0.011
Identities = 40/208 (19%), Positives = 87/208 (41%), Gaps = 31/208 (14%)
Query: 27 KHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDK 86
K + +E ++ E++R+K K + + +E+E+ + ++ + + +
Sbjct: 175 KRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGR 234
Query: 87 EKRKEEKVRASGDAKIKKEKENGFSSPPQIK-----------DEPEDDGYFVPPKEDIKP 135
+K +EEK ++ IK+ G + + D ED D P
Sbjct: 235 QKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSI------DYNP 288
Query: 136 LKRPRDEDD-------ADYKPKKIKTEDTK-----KEKKRKLEE--EEDGKLKKPKNKDK 181
L + R + A K+ K E ++ EK+R LEE +E+ +L+K + K+
Sbjct: 289 LYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEA 348
Query: 182 DKKVPEPDNKKKKPKKEEEQKWKWWEEE 209
++ + +KK + ++ W+ + E+
Sbjct: 349 KQRWDDRHWSQKKLDEMTDRDWRIFRED 376
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 68.6 bits (166), Expect = 2e-11
Identities = 43/192 (22%), Positives = 100/192 (52%), Gaps = 23/192 (11%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
+ D H +D+ +DRE R++E ++++REK E + ++ +++++ ++ E+
Sbjct: 38 KTEDRHSERDRQRDRE-RNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKER 96
Query: 77 HKDKHK--DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIK 134
D+H DR+++K+KE ++ D + +K+KE G + + + E D +E +
Sbjct: 97 ETDRHTETDRERQKQKEREMERVRDREREKQKEMG----RERQTDRETD------RERER 146
Query: 135 PLKRPRDEDDADYKPKKIKTEDT----KKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDN 190
+R R+ ++ KTED ++E+KR+ E + + K ++ + ++ E D
Sbjct: 147 QAERERETG------RERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDR 200
Query: 191 KKKKPKKEEEQK 202
K+ + ++ E ++
Sbjct: 201 KRDRQRESERER 212
Score = 67.4 bits (163), Expect = 5e-11
Identities = 42/214 (19%), Positives = 102/214 (47%), Gaps = 32/214 (14%)
Query: 7 HNDSQIEADFRLNDSHKHKDKHKDR------EHRHKEHKKEKDREKSKHSNSEHKDSEKK 60
H ++ E R + + D+ +DR E RH E +++DRE+++ + + + ++
Sbjct: 9 HTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQT 68
Query: 61 HKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEP 120
+E E+ + ++ ++ ++ ++RDKE+ + + + +KE+E +++D
Sbjct: 69 DREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE-----MERVRDR- 122
Query: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLE-EEEDGKLKKPKNK 179
+E K + R R D +T +E++R+ E E E G+ +K +++
Sbjct: 123 --------EREKQKEMGRERQTD-----------RETDRERERQAERERETGRERKTEDR 163
Query: 180 DKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPE 213
++++ +++K + +E ++ E ER E
Sbjct: 164 HRERERERKRERERKRETKERERHTDMERERQRE 197
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/163 (17%), Positives = 77/163 (47%), Gaps = 11/163 (6%)
Query: 40 KEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGD 99
+ K + H+ +E D +++ + + + K +D+H +RD+++ +E D
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 100 AKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKK 159
+E+E + + E E D ++ + +R RD++ + + E +K
Sbjct: 62 ----REREKQTDREGERQRERERD------RDRQRETERERDKERETDRHTETDRE-RQK 110
Query: 160 EKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
+K+R++E D + +K K ++++ +++++ + E E++
Sbjct: 111 QKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERE 153
Score = 40.0 bits (92), Expect = 0.008
Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEK-KHKEKEKT 67
+ Q E + K +D+H++RE +E K+E++R++ H D E+ + +E ++
Sbjct: 145 ERQAERERETGRERKTEDRHRERE---RERKRERERKRETKERERHTDMERERQRETDRK 201
Query: 68 KHKDGSSEKHKD 79
+ + SE+ +D
Sbjct: 202 RDRQRESERERD 213
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 67.8 bits (164), Expect = 4e-11
Identities = 57/202 (28%), Positives = 93/202 (46%), Gaps = 40/202 (19%)
Query: 22 HKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHK--------DSEKKHKEKEKTKHKDGS 73
HK +K K+ K +EK REK + + K +S++KH ++K K D S
Sbjct: 859 HKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNS 918
Query: 74 ----SEKHKDKHKDRDKEK----RKEEKVRASGDAKIKKEKENGF--------SSPPQIK 117
SEK K+K KDR+ +K R +E + + I++EK++ P +K
Sbjct: 919 EYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLK 978
Query: 118 DEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPK 177
++ +D+ PLK P D K KK K D KE+ + ++ + L K K
Sbjct: 979 EKTKDE-----------PLKTP----DGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLK 1023
Query: 178 NK-DKDKKVPEPDNKKKKPKKE 198
++ DK K P +K +PK++
Sbjct: 1024 SEADKPKPKSSPASKDTRPKEK 1045
Score = 67.8 bits (164), Expect = 4e-11
Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 49/227 (21%)
Query: 21 SHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKK----------HKE----KEK 66
S K K+K KDRE KE K +D+E +NS+H EKK H++ KEK
Sbjct: 923 SEKGKNKEKDRELDKKE--KSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEK 980
Query: 67 TKHK-----DGSSEKHKDKHKDRDKEKRK-EEKVRASGDAKIKKEKENGFSSPPQIKDEP 120
TK + DG + KDK DR KE+ K ++K++ + K+K E + K +P
Sbjct: 981 TKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEAD---------KPKP 1031
Query: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKP-------KKIKTEDTKKEKKRKLEEEEDGKL 173
+ P +D +P ++ DD K ++ E K+ K K++++E +L
Sbjct: 1032 KSS----PASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERL 1087
Query: 174 K-------KPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPE 213
+ K K+K+K K P K+ + + + + +E+ P+
Sbjct: 1088 RNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPK 1134
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/226 (27%), Positives = 101/226 (44%), Gaps = 23/226 (10%)
Query: 10 SQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKH 69
S IE L+ K D K + +H + KEK ++S+ + + E+K EKEK
Sbjct: 768 SAIEESIGLHLVEKEIDIEK--QEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIK 825
Query: 70 KDGSSEKHK-------DKHKDRDK------EKRKEEKVRASGDAKIKK----EKENGFSS 112
+ SEK K DK K++DK EK +E ++ A IKK EK
Sbjct: 826 HEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMD 885
Query: 113 PPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPK---KIKTEDTKKEKKRKLEEEE 169
K++PE + + KE K+ + D+++Y K K +D + +KK K ++E
Sbjct: 886 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 945
Query: 170 DGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEE-RYPEG 214
+ K+ ++KK D K + +K K K +E + P+G
Sbjct: 946 SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDG 991
Score = 63.2 bits (152), Expect = 9e-10
Identities = 92/390 (23%), Positives = 159/390 (40%), Gaps = 77/390 (19%)
Query: 10 SQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKH 69
S+ + DF L K K KD +H + +K K + KHKE+EK KH
Sbjct: 583 SKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKH 642
Query: 70 KDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPP 129
K E K+K+K +D K + V + KEN F S DE ED F+
Sbjct: 643 KK-EIEGEKEKYKTKDSAKELQRSVEFDREF----WKENFFKS-----DETED--LFLNM 690
Query: 130 KEDIKPLKRPRD-----EDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD-KDK 183
+ + L++ +DD K K + E KE++ K+++E + ++ K KD K++
Sbjct: 691 EHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEE 750
Query: 184 KVPEPDNK-------------------------------------KKKPKKEEEQKWKWW 206
+ P +K K+KP+K + K K
Sbjct: 751 RENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDI 810
Query: 207 EEERYPEGIKWKFLEHKGPV------FAPPYEPLPENVKFY--YDGKVMKLSPKAEEVAT 258
E+ K K ++H+ + + + E K Y + K K K++ A
Sbjct: 811 EKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAA 870
Query: 259 FFAKMLDHEYTTKEIFRKNFFKDWRKE---MTNEEKNIITNLSKCDFTQMSQYFKAQ--- 312
K D E + +++ RK+ + KE ++EK+++ +K + S+Y K++
Sbjct: 871 -IKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNK--QSDNSEYSKSEKGK 927
Query: 313 -TEARKQMSKEEKLKIKEE----NEKLLKE 337
E +++ K+EK + KE N K ++E
Sbjct: 928 NKEKDRELDKKEKSRDKESINITNSKHIQE 957
Score = 58.9 bits (141), Expect = 2e-08
Identities = 99/419 (23%), Positives = 171/419 (40%), Gaps = 87/419 (20%)
Query: 4 DHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDR-----EKSKHS-------- 50
D H+ + +D L K K + +HKE +KEK + EK K+
Sbjct: 603 DEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKEL 662
Query: 51 --------------------------NSEHKD--SEKKHKEKEKTKHKDGSSEKH--KDK 80
N EH+ EKK K ++ K + EKH K++
Sbjct: 663 QRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKER 722
Query: 81 HKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPR 140
+ +++K K+E ++ + KIK KE + P E G + E+ L
Sbjct: 723 NFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLG--MSAIEESIGLHLVE 780
Query: 141 DEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPK---- 196
E D + + K IK K EK+ +++E++ K+++ K +K+KK+ + ++K +K K
Sbjct: 781 KEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMER-KTFEKEKKI-KHEHKSEKDKLDLS 838
Query: 197 ------KEEEQKWKWWEEERYPEGIKWKFL----------EHKGPVFAPPYEPLPENVKF 240
KE+++ + E+ + EG K K + + + + PE +
Sbjct: 839 ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 898
Query: 241 YYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDW---RKEMTNEEKNI-ITN 296
+ K L K K D+ +K KN KD +KE + ++++I ITN
Sbjct: 899 LAESKEKHLMEKKN-------KQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITN 951
Query: 297 LSKCDFTQMSQYF---KAQTE---ARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKER 349
+ S KAQ E + K+ +K+E LK + EK K+ +D +KER
Sbjct: 952 SKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD---IDRYKER 1007
Score = 57.0 bits (136), Expect = 6e-08
Identities = 85/343 (24%), Positives = 133/343 (38%), Gaps = 102/343 (29%)
Query: 39 KKEKDREKSKHSNSEH----KDSEKKHKEKE------------KTKHKDGSS-EKHKDKH 81
K K +EKSKH H + S K K+++ K K+G + +KHK KH
Sbjct: 575 KSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKH 634
Query: 82 KDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRD 141
K+R+KEK K+E I+ EKE K+ K L+R +
Sbjct: 635 KEREKEKHKKE---------IEGEKEK------------------YKTKDSAKELQRSVE 667
Query: 142 EDDADYKPKKIKTEDTKK------------EKKRKLEEE-EDGKLKKPKNKDKDKKVPEP 188
D +K K+++T+ EKK KLE+ +D K K K+ K++ E
Sbjct: 668 FDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEE 727
Query: 189 DNKKKK--PKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKV 246
+K KK K E+K K +EER EN+ D +
Sbjct: 728 RDKIKKESEKSFREEKIKDLKEER-------------------------ENIPTDKDSEF 762
Query: 247 MKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMS 306
L A E + + KEI ++ +EK+I + K +
Sbjct: 763 TSLGMSAIE------ESIGLHLVEKEI-----------DIEKQEKHIKESKEKPEKRSQI 805
Query: 307 QYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKER 349
+ + RK KE+K+K + ++EK + C+ D KE+
Sbjct: 806 KEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECV-DKIKEK 847
Score = 43.9 bits (102), Expect = 6e-04
Identities = 103/490 (21%), Positives = 204/490 (41%), Gaps = 48/490 (9%)
Query: 19 NDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKD-----GS 73
+D K+ EH+ K K K + ++K+ ++ EK+ KE + +
Sbjct: 429 SDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDC 488
Query: 74 SEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKEN--GFSSPPQIKDEPEDDGYFVPP-- 129
SEK +++ R K++ K ++ G S + E + P
Sbjct: 489 SEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGS 548
Query: 130 -KEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEE---EDGKLKKPKNKDKDKKV 185
+ ++P D ++++ P+ + K ++K K +++ E G+ K KD+D
Sbjct: 549 SEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHS- 607
Query: 186 PEPDN---------KKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPE 236
P +N K+ K K+ + K K E+E++ + I+ + ++K A + L
Sbjct: 608 PTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSA---KELQR 664
Query: 237 NVKFYYDGKVMKLS-PKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIIT 295
+V+F D + K + K++E F M +HE T E + K+ + + + +EK++
Sbjct: 665 SVEF--DREFWKENFFKSDETEDLFLNM-EHESLTLE-KKSKLEKNIKDDKSTKEKHV-- 718
Query: 296 NLSKCDFTQMSQYFKAQTEARKQMSKEEKLK-IKEENEKLL----KEYGFCIMDNHKERI 350
+ +F + K ++E + +EEK+K +KEE E + E+ M +E I
Sbjct: 719 -SKERNFKEERDKIKKESE---KSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESI 774
Query: 351 ANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKV 410
+E + H K K PE KD + K K+++H++K
Sbjct: 775 GLHLVEKEIDIEKQEKHIKESKEK----PEKRSQIKEKDIEKMERKTFEKEKKIKHEHKS 830
Query: 411 TW-LVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWK-SK 468
+ +E + + L K K+ +K + +KK D+ +++ + D K K
Sbjct: 831 EKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK 890
Query: 469 EMKVRQRAVA 478
E ++R +A
Sbjct: 891 EKPEKERHLA 900
Score = 36.2 bits (82), Expect = 0.12
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 107 ENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADY-KPKKIKTEDTKKEKKRK- 164
++GF+ P Q ++ D KP R + A Y K KI+ D KE K K
Sbjct: 3 KSGFTKPIQSENSDSDSNMVE------KPYGRKSKDKIASYSKTPKIERSDVSKEMKEKS 56
Query: 165 -LEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
++ + + +N+++D + +KKK KKE K
Sbjct: 57 SMKRKLPFTISPSRNEERDSDTEKEGPEKKKTKKEAGNK 95
Score = 35.4 bits (80), Expect = 0.20
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 22 HKHKDKHKDRE---HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHK 78
HK K K K++E +R+ K KD+EK+KH+ +E K+KE ++K + + K
Sbjct: 1075 HKEKIKQKEKERLRNRNCLELKIKDKEKTKHT-----PTESKNKELTRSKSSEVTDAYTK 1129
Query: 79 DKHKDRDKEKRKEEKVRASGDAKIKKE---KENGFSSPPQIKDE 119
+K + +D + + V + K +N + P+ ++E
Sbjct: 1130 EK-QPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1172
Score = 33.9 bits (76), Expect = 0.58
Identities = 34/132 (25%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 32 EHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHK-DGSSEKHKDKHKDRDKEKRK 90
E + K+K SK E D K+ KEK K K + +++ +D D EK
Sbjct: 23 EKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEERDSDTEKEG 82
Query: 91 EEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPK 150
EK K KKE N S+P I GY + ++ + L + D++
Sbjct: 83 PEK------KKTKKEAGNKKSTPVSIL-----FGYPLSERKQMALLMQMTARDNSPDSTP 131
Query: 151 KIKTEDTKKEKK 162
++ T +KK
Sbjct: 132 NHPSQTTPAQKK 143
Score = 32.0 bits (71), Expect = 2.2
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 79 DKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKR 138
D+H R +++++ E K+EK S K +P Y D + L+
Sbjct: 354 DRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQN 413
Query: 139 PRDEDDADYKPKKIKTE-DTKKEKKRKLEEEEDGKLK-KPKNKDKDKKVPEPDNKKKKPK 196
+ P+ ++ TKKE E ++ GK+K K KN++K+K +N++ K +
Sbjct: 414 KKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNK-----ENQELKQE 468
Query: 197 KEEEQ 201
KE ++
Sbjct: 469 KEGKE 473
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 67.8 bits (164), Expect = 4e-11
Identities = 57/202 (28%), Positives = 93/202 (46%), Gaps = 40/202 (19%)
Query: 22 HKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHK--------DSEKKHKEKEKTKHKDGS 73
HK +K K+ K +EK REK + + K +S++KH ++K K D S
Sbjct: 882 HKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNS 941
Query: 74 ----SEKHKDKHKDRDKEK----RKEEKVRASGDAKIKKEKENGF--------SSPPQIK 117
SEK K+K KDR+ +K R +E + + I++EK++ P +K
Sbjct: 942 EYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLK 1001
Query: 118 DEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPK 177
++ +D+ PLK P D K KK K D KE+ + ++ + L K K
Sbjct: 1002 EKTKDE-----------PLKTP----DGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLK 1046
Query: 178 NK-DKDKKVPEPDNKKKKPKKE 198
++ DK K P +K +PK++
Sbjct: 1047 SEADKPKPKSSPASKDTRPKEK 1068
Score = 67.8 bits (164), Expect = 4e-11
Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 49/227 (21%)
Query: 21 SHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKK----------HKE----KEK 66
S K K+K KDRE KE K +D+E +NS+H EKK H++ KEK
Sbjct: 946 SEKGKNKEKDRELDKKE--KSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEK 1003
Query: 67 TKHK-----DGSSEKHKDKHKDRDKEKRK-EEKVRASGDAKIKKEKENGFSSPPQIKDEP 120
TK + DG + KDK DR KE+ K ++K++ + K+K E + K +P
Sbjct: 1004 TKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEAD---------KPKP 1054
Query: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKP-------KKIKTEDTKKEKKRKLEEEEDGKL 173
+ P +D +P ++ DD K ++ E K+ K K++++E +L
Sbjct: 1055 KSS----PASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERL 1110
Query: 174 K-------KPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPE 213
+ K K+K+K K P K+ + + + + +E+ P+
Sbjct: 1111 RNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPK 1157
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/226 (27%), Positives = 101/226 (44%), Gaps = 23/226 (10%)
Query: 10 SQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKH 69
S IE L+ K D K + +H + KEK ++S+ + + E+K EKEK
Sbjct: 791 SAIEESIGLHLVEKEIDIEK--QEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIK 848
Query: 70 KDGSSEKHK-------DKHKDRDK------EKRKEEKVRASGDAKIKK----EKENGFSS 112
+ SEK K DK K++DK EK +E ++ A IKK EK
Sbjct: 849 HEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMD 908
Query: 113 PPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPK---KIKTEDTKKEKKRKLEEEE 169
K++PE + + KE K+ + D+++Y K K +D + +KK K ++E
Sbjct: 909 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 968
Query: 170 DGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEE-RYPEG 214
+ K+ ++KK D K + +K K K +E + P+G
Sbjct: 969 SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDG 1014
Score = 63.2 bits (152), Expect = 9e-10
Identities = 92/390 (23%), Positives = 159/390 (40%), Gaps = 77/390 (19%)
Query: 10 SQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKH 69
S+ + DF L K K KD +H + +K K + KHKE+EK KH
Sbjct: 606 SKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKH 665
Query: 70 KDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPP 129
K E K+K+K +D K + V + KEN F S DE ED F+
Sbjct: 666 KK-EIEGEKEKYKTKDSAKELQRSVEFDREF----WKENFFKS-----DETED--LFLNM 713
Query: 130 KEDIKPLKRPRD-----EDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD-KDK 183
+ + L++ +DD K K + E KE++ K+++E + ++ K KD K++
Sbjct: 714 EHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEE 773
Query: 184 KVPEPDNK-------------------------------------KKKPKKEEEQKWKWW 206
+ P +K K+KP+K + K K
Sbjct: 774 RENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDI 833
Query: 207 EEERYPEGIKWKFLEHKGPV------FAPPYEPLPENVKFY--YDGKVMKLSPKAEEVAT 258
E+ K K ++H+ + + + E K Y + K K K++ A
Sbjct: 834 EKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAA 893
Query: 259 FFAKMLDHEYTTKEIFRKNFFKDWRKE---MTNEEKNIITNLSKCDFTQMSQYFKAQ--- 312
K D E + +++ RK+ + KE ++EK+++ +K + S+Y K++
Sbjct: 894 -IKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNK--QSDNSEYSKSEKGK 950
Query: 313 -TEARKQMSKEEKLKIKEE----NEKLLKE 337
E +++ K+EK + KE N K ++E
Sbjct: 951 NKEKDRELDKKEKSRDKESINITNSKHIQE 980
Score = 58.9 bits (141), Expect = 2e-08
Identities = 99/419 (23%), Positives = 171/419 (40%), Gaps = 87/419 (20%)
Query: 4 DHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDR-----EKSKHS-------- 50
D H+ + +D L K K + +HKE +KEK + EK K+
Sbjct: 626 DEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKEL 685
Query: 51 --------------------------NSEHKD--SEKKHKEKEKTKHKDGSSEKH--KDK 80
N EH+ EKK K ++ K + EKH K++
Sbjct: 686 QRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKER 745
Query: 81 HKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPR 140
+ +++K K+E ++ + KIK KE + P E G + E+ L
Sbjct: 746 NFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLG--MSAIEESIGLHLVE 803
Query: 141 DEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPK---- 196
E D + + K IK K EK+ +++E++ K+++ K +K+KK+ + ++K +K K
Sbjct: 804 KEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMER-KTFEKEKKI-KHEHKSEKDKLDLS 861
Query: 197 ------KEEEQKWKWWEEERYPEGIKWKFL----------EHKGPVFAPPYEPLPENVKF 240
KE+++ + E+ + EG K K + + + + PE +
Sbjct: 862 ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 921
Query: 241 YYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDW---RKEMTNEEKNI-ITN 296
+ K L K K D+ +K KN KD +KE + ++++I ITN
Sbjct: 922 LAESKEKHLMEKKN-------KQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITN 974
Query: 297 LSKCDFTQMSQYF---KAQTE---ARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKER 349
+ S KAQ E + K+ +K+E LK + EK K+ +D +KER
Sbjct: 975 SKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD---IDRYKER 1030
Score = 57.0 bits (136), Expect = 6e-08
Identities = 85/343 (24%), Positives = 133/343 (38%), Gaps = 102/343 (29%)
Query: 39 KKEKDREKSKHSNSEH----KDSEKKHKEKE------------KTKHKDGSS-EKHKDKH 81
K K +EKSKH H + S K K+++ K K+G + +KHK KH
Sbjct: 598 KSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKH 657
Query: 82 KDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRD 141
K+R+KEK K+E I+ EKE K+ K L+R +
Sbjct: 658 KEREKEKHKKE---------IEGEKEK------------------YKTKDSAKELQRSVE 690
Query: 142 EDDADYKPKKIKTEDTKK------------EKKRKLEEE-EDGKLKKPKNKDKDKKVPEP 188
D +K K+++T+ EKK KLE+ +D K K K+ K++ E
Sbjct: 691 FDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEE 750
Query: 189 DNKKKK--PKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKV 246
+K KK K E+K K +EER EN+ D +
Sbjct: 751 RDKIKKESEKSFREEKIKDLKEER-------------------------ENIPTDKDSEF 785
Query: 247 MKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMS 306
L A E + + KEI ++ +EK+I + K +
Sbjct: 786 TSLGMSAIE------ESIGLHLVEKEI-----------DIEKQEKHIKESKEKPEKRSQI 828
Query: 307 QYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKER 349
+ + RK KE+K+K + ++EK + C+ D KE+
Sbjct: 829 KEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECV-DKIKEK 870
Score = 43.9 bits (102), Expect = 6e-04
Identities = 103/490 (21%), Positives = 204/490 (41%), Gaps = 48/490 (9%)
Query: 19 NDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKD-----GS 73
+D K+ EH+ K K K + ++K+ ++ EK+ KE + +
Sbjct: 452 SDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDC 511
Query: 74 SEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKEN--GFSSPPQIKDEPEDDGYFVPP-- 129
SEK +++ R K++ K ++ G S + E + P
Sbjct: 512 SEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGS 571
Query: 130 -KEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEE---EDGKLKKPKNKDKDKKV 185
+ ++P D ++++ P+ + K ++K K +++ E G+ K KD+D
Sbjct: 572 SEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHS- 630
Query: 186 PEPDN---------KKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPE 236
P +N K+ K K+ + K K E+E++ + I+ + ++K A + L
Sbjct: 631 PTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSA---KELQR 687
Query: 237 NVKFYYDGKVMKLS-PKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIIT 295
+V+F D + K + K++E F M +HE T E + K+ + + + +EK++
Sbjct: 688 SVEF--DREFWKENFFKSDETEDLFLNM-EHESLTLE-KKSKLEKNIKDDKSTKEKHV-- 741
Query: 296 NLSKCDFTQMSQYFKAQTEARKQMSKEEKLK-IKEENEKLL----KEYGFCIMDNHKERI 350
+ +F + K ++E + +EEK+K +KEE E + E+ M +E I
Sbjct: 742 -SKERNFKEERDKIKKESE---KSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESI 797
Query: 351 ANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKV 410
+E + H K K PE KD + K K+++H++K
Sbjct: 798 GLHLVEKEIDIEKQEKHIKESKEK----PEKRSQIKEKDIEKMERKTFEKEKKIKHEHKS 853
Query: 411 TW-LVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWK-SK 468
+ +E + + L K K+ +K + +KK D+ +++ + D K K
Sbjct: 854 EKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK 913
Query: 469 EMKVRQRAVA 478
E ++R +A
Sbjct: 914 EKPEKERHLA 923
Score = 35.4 bits (80), Expect = 0.20
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 22 HKHKDKHKDRE---HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHK 78
HK K K K++E +R+ K KD+EK+KH+ +E K+KE ++K + + K
Sbjct: 1098 HKEKIKQKEKERLRNRNCLELKIKDKEKTKHT-----PTESKNKELTRSKSSEVTDAYTK 1152
Query: 79 DKHKDRDKEKRKEEKVRASGDAKIKKE---KENGFSSPPQIKDE 119
+K + +D + + V + K +N + P+ ++E
Sbjct: 1153 EK-QPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1195
Score = 32.0 bits (71), Expect = 2.2
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 79 DKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKR 138
D+H R +++++ E K+EK S K +P Y D + L+
Sbjct: 377 DRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQN 436
Query: 139 PRDEDDADYKPKKIKTE-DTKKEKKRKLEEEEDGKLK-KPKNKDKDKKVPEPDNKKKKPK 196
+ P+ ++ TKKE E ++ GK+K K KN++K+K +N++ K +
Sbjct: 437 KKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNK-----ENQELKQE 491
Query: 197 KEEEQ 201
KE ++
Sbjct: 492 KEGKE 496
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 67.8 bits (164), Expect = 4e-11
Identities = 46/202 (22%), Positives = 92/202 (45%), Gaps = 13/202 (6%)
Query: 3 GDHLHNDSQIEADFRLNDSHKHKDKHKDREH-RHKEHKKEKDREKSKHSNSEHKDSEKKH 61
GD D + E + N+ + +D+ D+E +E ++E+ RE+SK S + EKKH
Sbjct: 347 GDRRDRDREREKE---NERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKH 403
Query: 62 KE-KEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEP 120
KE K+ +H+D + K+K R + + ++ + R+ K+ + + K+E
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463
Query: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD 180
++ K + + + D+ K KK + KEK RK ++ K+ +
Sbjct: 464 KE-------KSNKRSRSGSQGRTDSVEKSKK-REHSPSKEKSRKRSRSKERSHKRDHSDS 515
Query: 181 KDKKVPEPDNKKKKPKKEEEQK 202
KD+ + + ++E ++K
Sbjct: 516 KDQSDKHDRRRSQSIEQESQEK 537
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 12/186 (6%)
Query: 20 DSHKHKDKHKDR-EHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHK 78
D ++K + R E KE +KE+ R +S E + S + + + +++ +D K
Sbjct: 292 DRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD-----RK 346
Query: 79 DKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKR 138
+DRD+E+ KE + D KE+ N + ++ + + +++ K
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKERGN---EREKERERSRERSKEQRSRGEVEEKKH 403
Query: 139 PRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKE 198
D+DD ++ K D+KKEKK + K + K +K+K K +
Sbjct: 404 KEDKDDRRHRDDK---RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHK 460
Query: 199 EEQKWK 204
E K K
Sbjct: 461 NESKEK 466
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 34/171 (19%)
Query: 20 DSHKHKDKHKDREHR--------HKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKD 71
+ KHK+ DR HR K+H + + RE+ S S +++ K+ + + K K
Sbjct: 399 EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK--- 455
Query: 72 GSSEKHKDKHKDR-DKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPK 130
S KHK++ K++ +K R + R K KK + SP + K +
Sbjct: 456 --SSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREH----SPSKEKSR---------KR 500
Query: 131 EDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDK 181
K RD D+ K + K +++R E++ + K+ KNKD+
Sbjct: 501 SRSKERSHKRDHSDS-------KDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 54.7 bits (130), Expect = 3e-07
Identities = 35/197 (17%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 17 RLNDSHKHKDKHKDR--EHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSS 74
R + H+ + + +DR + R ++ ++EK+ E+ + + ++ +EKE+ + ++ S
Sbjct: 331 RSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390
Query: 75 EKH------KDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVP 128
E+ + KHK+ DK+ R+ + + K + + + + G
Sbjct: 391 EQRSRGEVEEKKHKE-DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449
Query: 129 PKEDIKPLKRPRDEDDADYKPKKI----KTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKK 184
+ K K + + K + +T+ +K KKR+ ++ K+ ++K++ K
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHK 509
Query: 185 VPEPDNKKKKPKKEEEQ 201
D+K + K + +
Sbjct: 510 RDHSDSKDQSDKHDRRR 526
Score = 53.9 bits (128), Expect = 5e-07
Identities = 39/185 (21%), Positives = 83/185 (44%), Gaps = 22/185 (11%)
Query: 17 RLNDSHKHKDKHKDREH---RHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGS 73
RL K ++K + R R E ++ + RE+ + S + ++K +++ + ++
Sbjct: 303 RLEREAKEREKERRRSRSIDRGLERRRSRSRERHR---SRSRSRDRKGDRRDRDREREKE 359
Query: 74 SEKHKDKHKDRDKEKRKE-EKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKED 132
+E+ + + +D DKE+ E EK R + K+++ G + K++ +D
Sbjct: 360 NERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD---------- 409
Query: 133 IKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKK 192
+R RD D D K +K + +E+K + K+ +++ K+K + K
Sbjct: 410 ----RRHRD-DKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESK 464
Query: 193 KKPKK 197
+K K
Sbjct: 465 EKSNK 469
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/200 (17%), Positives = 91/200 (45%), Gaps = 11/200 (5%)
Query: 11 QIEADFRLNDSHKHKDKHKDR---EHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
++E + + + + + + DR R + ++ + R +S+ + +D +++ +EKE
Sbjct: 303 RLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE-REKENE 361
Query: 68 KHKDGSSEKHKDKHKDRDKE----KRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDD 123
+ + + K++ +R+KE + + ++ R+ G+ + KK KE+ + +D+ D
Sbjct: 362 RGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKED--KDDRRHRDDKRDS 419
Query: 124 GYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLE-EEEDGKLKKPKNKDKD 182
++ R + K+ ++ +K K K E +E+ K + ++ +
Sbjct: 420 KKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRT 479
Query: 183 KKVPEPDNKKKKPKKEEEQK 202
V + ++ P KE+ +K
Sbjct: 480 DSVEKSKKREHSPSKEKSRK 499
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/187 (18%), Positives = 80/187 (42%), Gaps = 15/187 (8%)
Query: 29 KDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEK 88
KD + +E + +R +S+ + + ++ H++G D+ +R+KE+
Sbjct: 242 KDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKER 301
Query: 89 RKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDED----- 143
++ E+ A K ++ + + + + D K +R RD +
Sbjct: 302 QRLER-EAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN 360
Query: 144 ------DADYKPKKIKTEDTKKEKKRKLEEEE--DGKLKKPKNK-DKDKKVPEPDNKKKK 194
D DY ++ + ++E+ R+ +E+ G++++ K+K DKD + D + K
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSK 420
Query: 195 PKKEEEQ 201
+K+ +
Sbjct: 421 KEKKHSR 427
Score = 34.3 bits (77), Expect = 0.45
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 7/73 (9%)
Query: 2 SGDHLHNDSQIEADFRLNDSHKHKDKH----KDREHR--HKEHKKEKDREKSKHSNS-EH 54
SG DS ++ R + K K + K+R H+ H + K + D+ + S S E
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532
Query: 55 KDSEKKHKEKEKT 67
+ EK+HK K++T
Sbjct: 533 ESQEKQHKNKDET 545
>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
sapiens]
Length = 558
Score = 67.8 bits (164), Expect = 4e-11
Identities = 50/212 (23%), Positives = 100/212 (47%), Gaps = 25/212 (11%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSE-KKHKEKEKTKHKDGSSEKHK 78
D H+ K +D+E+ + + K+R+ +H + H+DS K+H++++K + +D +
Sbjct: 318 DQHQQKQS-RDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDR 376
Query: 79 DKHKDRDKEK---RKEEKVRASGDAK------IKKEKENGFSSPPQIKDE--PEDDGYFV 127
+++D+EK R++E+ R D K+EK +++ E +D Y
Sbjct: 377 VWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRD 436
Query: 128 PPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPE 187
K ++ R++D + P + K + L++E K++ KDK++ +
Sbjct: 437 REKREVGVQSSERNQDRKESSP-------NSRAKDKFLDQERSNKMRN-MAKDKERNQEK 488
Query: 188 PDNKKK----KPKKEEEQKWKWWEEERYPEGI 215
P N + K + EE + K E+ER PE +
Sbjct: 489 PSNSESSLGAKHRLTEEGQEKGKEQERPPEAV 520
Score = 61.6 bits (148), Expect = 3e-09
Identities = 63/284 (22%), Positives = 122/284 (42%), Gaps = 28/284 (9%)
Query: 13 EADFRLNDSHKHKDK------HKDREHRH-----KEHKKEKDREKSKHSNSE--HKDSEK 59
E DF+ + S H H R H + H+K +D+ + K S + H
Sbjct: 277 ENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRD 336
Query: 60 KHKEKEKTKHKDGSS-EKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKD 118
KE++ +H++ S + H +H+ DK + ++++ R+ K +K++E +S Q +D
Sbjct: 337 YRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREK-YSQREQERD 395
Query: 119 EPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRK------LEEEEDGK 172
++D P ++ K K E+ + ++ + D ++++++ E +D K
Sbjct: 396 RQQND-QNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRK 454
Query: 173 LKKPKNKDKDKKV-PEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLE---HKGPVFA 228
P ++ KDK + E NK + K++E+ + G K + E KG
Sbjct: 455 ESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQE 514
Query: 229 PPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKE 272
P E + + K + VM S + +A A++ Y KE
Sbjct: 515 RPPEAVSKFAKRNNEETVM--SARDRYLARQMARVNAKTYIEKE 556
Score = 46.6 bits (109), Expect = 9e-05
Identities = 38/211 (18%), Positives = 93/211 (44%), Gaps = 15/211 (7%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTK 68
DS +A +D + + R + +E E KH S++ + T+
Sbjct: 247 DSDFDAKSSADD-----EIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTR 301
Query: 69 HKDGSSEKHKDKHKDRDKEKRKEEKVRAS--GDAKIKKEKENGFSSPPQIKDEPEDDGYF 126
H S + K D+ ++K+ + + + D +KE+++ + ++ D ++
Sbjct: 302 HHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDS-----HRHREASHRDSHW 356
Query: 127 VPPKEDIKPLKR-PRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
+++ KP R R+ D +K +K + + +++E++R ++ + + + K++ K
Sbjct: 357 KRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKA 416
Query: 186 PEPDNKKKKPKKEEEQKWKWWEEERYPEGIK 216
E K +K + E K++ + E+ G++
Sbjct: 417 KEEHMKVRKERYENNDKYR--DREKREVGVQ 445
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/172 (20%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Query: 7 HNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKH---KE 63
++ + E D + ND ++ +K + E + + K R++ +N +++D EK+ +
Sbjct: 387 YSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQS 446
Query: 64 KEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSS---PPQIKDEP 120
E+ + + SS + K K D+E+ + + A + +++ N SS ++ +E
Sbjct: 447 SERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEG 506
Query: 121 EDDG--YFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEED 170
++ G PP+ K KR +E + + + + + K +E+E+D
Sbjct: 507 QEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD 558
Score = 30.4 bits (67), Expect = 6.4
Identities = 70/355 (19%), Positives = 133/355 (37%), Gaps = 48/355 (13%)
Query: 24 HKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKD 83
+ + K +E + + KDR K K+ ++ K E + KE+EK K E+ +K +
Sbjct: 79 YDEMQKKKEENNPKLLLGKDR-KPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEF 137
Query: 84 RDKE----KRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRP 139
DKE ++K++ + + ++++ + + + + G++ L +
Sbjct: 138 DDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFY------RHLLNQA 191
Query: 140 RDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK---DKDKKVPE-PD-----N 190
E++ + K+EK R E K + P+ K D KV E PD +
Sbjct: 192 VGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFD 251
Query: 191 KKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFA-PPYEPLPENVKFYYDGKVMKL 249
K E E+ E+ E + F H+ + P E + + + G
Sbjct: 252 AKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSR 311
Query: 250 SPKAEEVATFFAKMLDHE--YTTKEI--------FRKNFFKD--WRKEMTNEEKNIITNL 297
+ E + D E YT ++ R+ +D W++ ++
Sbjct: 312 GHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQR 371
Query: 298 SKCDFT-----QMSQYFKAQTEARKQMS----------KEEKLKIKEENEKLLKE 337
+ D +Y + + E +Q + KEEK K KEE+ K+ KE
Sbjct: 372 ERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKE 426
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 67.4 bits (163), Expect = 5e-11
Identities = 63/332 (18%), Positives = 164/332 (49%), Gaps = 31/332 (9%)
Query: 29 KDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKH-KDRDKE 87
++ E R +E K K EK ++ E K +E+E+ + + ++K ++++KE
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 88 KRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPE-----DDGYFVPPKEDIKPLKRPRDE 142
R+++++R + ++++++E + +++++ E ++ + K+ + ++ RD+
Sbjct: 337 LREQKELREQ-EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 143 DDADY--------KPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPD---NK 191
++ + K ++++ ++ E+ K+ EE+ + ++ K +D+++K+ E + +
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 192 KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSP 251
+KK ++EEE + E+ + E W+ E + + LPE + ++ + K+
Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEW-----QQQRLPEQKEKLWEQE--KMQE 508
Query: 252 KAEEVATFFAKMLDHEY---TTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQY 308
+ E++ K+ D E K+++R+ ++ +M +E+ + K +
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERME 568
Query: 309 FKAQTEARKQMSKEEKLKIKE---ENEKLLKE 337
K Q + +K +EEK++ +E E EK ++E
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Score = 67.4 bits (163), Expect = 5e-11
Identities = 74/371 (19%), Positives = 171/371 (46%), Gaps = 50/371 (13%)
Query: 13 EADFRLNDSH---KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKH 69
E D RL + + ++K ++ + +E KK +++EK E E++ +E+EK
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460
Query: 70 KDGSSEKHKD-------------KHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQI 116
++ + + ++ + K+ +++ E+K + K+++++E + +I
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 117 KDEPEDDGY--------FVPPKED--IKPLKRPRDED----DADYKPKKIKTEDTKK--E 160
+D+ E G + +ED + ++ RD++ D + + +K E KK +
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 161 KKRKLEEEEDGKLKKPKNKDKDKKVPEPDNK-KKKPKKEEEQKWKWWEEERYPEGIKWKF 219
++ K+ EEE + ++ K +++++ + E + K +++ +K +EQ+ K WE+E + + K
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 220 LEHKGPVFAP-----PYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIF 274
E + ++ + LPE + ++ + M+ K +E + E T+E
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 275 RKNFFKDWRKEMTNEEKNIITNLSKC---DFTQMSQYFKAQTEARKQMSKEEKL-----K 326
+K W +E EE+++ K + Q K Q + K +EE++ K
Sbjct: 701 KKT----WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 327 IKEENEKLLKE 337
+ E+ EK+ ++
Sbjct: 757 MWEQEEKMWEQ 767
Score = 67.0 bits (162), Expect = 6e-11
Identities = 68/348 (19%), Positives = 160/348 (45%), Gaps = 33/348 (9%)
Query: 13 EADFRLNDSHKHKDKHK----DREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT- 67
E + R + K + K + R +E K + EK ++ EK+ +E+EK
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDE-----PED 122
+ + E+ + + +K +EEK+R + K+ +++E + Q++++ ++
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQ-EEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 123 DGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKD 182
+ + + + +R R+++ + +K++ E +E+++K ++E+ ++ + ++++
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 183 KKVPEPD----NKKKKPKKEEEQKW----KWWEEERYPEGIK--W---KFLEHKGPVFAP 229
KK+ E + +++K +K+EE W K W+++R PE + W K E + ++
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 230 PYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNE 289
E + + + + K M K E D + +E R K W +E E
Sbjct: 517 E-EKIRDQEEMWGQEKKMWRQEKMRE-------QEDQMWEQEEKMRDQEQKMWDQEERME 568
Query: 290 EKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKE 337
+K D + + + E K+M +EE++ ++E+ EK+ ++
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM-MREQEEKMQEQ 615
Score = 67.0 bits (162), Expect = 6e-11
Identities = 67/366 (18%), Positives = 169/366 (46%), Gaps = 52/366 (14%)
Query: 11 QIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSE-HKDSEKKHKEKEKTKH 69
Q+E + + K +D+E + +E ++ ++REK E ++ E+K +++E+
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 70 KDGSSE-------KHKDKHKDRDKEKRKEEKV------------------RASGDAKIKK 104
+ E + K+K +++K + +EEK+ + K+++
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 105 EKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRK 164
+++ + +++D+ + + +E+ K E + +K++ E+ +E+++K
Sbjct: 542 QEDQMWEQEEKMRDQEQK----MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 165 L-EEEEDGKLKKPKNKDKDKKVPEPDNK----KKKPKKEEEQKW-----------KWWEE 208
+ EEEE + ++ K +++++K+ E + K ++K +++EE+ W K WE+
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 209 ERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEY 268
+R PE K K EH+ E + E + ++ + M+ + +E T+ + + E
Sbjct: 658 QRLPEQ-KEKLWEHEK---MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 269 TTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIK 328
+ +E R+ ++ + M +E+ + K + + + + ++ E+ ++
Sbjct: 714 SMRE--REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 329 EENEKL 334
E+ EKL
Sbjct: 772 EQKEKL 777
Score = 66.2 bits (160), Expect = 1e-10
Identities = 64/345 (18%), Positives = 160/345 (46%), Gaps = 43/345 (12%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTK 68
+ ++ + R+ + K + ++ +E +E++ + + + EK +++EK
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641
Query: 69 HKDGSSEKHKDKHKDRDKEKRKEEKV----RASGDAKIKKEKENGFSSPPQIKDEPEDDG 124
++ + ++K ++ + ++EK+ + K+++++E +
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW-------------- 687
Query: 125 YFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKL-EEEEDGKLKKPKNKDKDK 183
E K K+ ++++ + +K++ E++ +E+++K+ EEEE + ++ K +++++
Sbjct: 688 ------EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 184 KVPEPDNKK-KKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYY 242
K+ E + + ++ +K EQ+ K WE++R PE K K EH E + E K +
Sbjct: 742 KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ-KEKLWEH---------EKMQEQEKIWE 791
Query: 243 DGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKD---WRKE--MTNEEKNIITNL 297
+ K+ + E++ KM E + K + ++ W +E M +E+ +
Sbjct: 792 QEE--KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQE 849
Query: 298 SKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCI 342
K + Q K + + K +EEK++ +EE + +E +C+
Sbjct: 850 EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCV 894
Score = 64.3 bits (155), Expect = 4e-10
Identities = 59/327 (18%), Positives = 151/327 (46%), Gaps = 35/327 (10%)
Query: 27 KHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDK 86
+ +++E R +E + + +E + + EK +++EK + ++ + +++ +++K
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 383
Query: 87 EKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPL---KRPRDED 143
+ R++E+ + ++ ++ E +++++ + +E+ K K+ RD++
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 443
Query: 144 DADYKPKKIKT--------EDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKP 195
+ + ++I+ E+T +E++ K++++E+ ++ + + + +++PE K +
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 196 KKEEEQKWKWWEEERY---------PEGIKW---KFLEHKGPVFAPPYEPLPENVKFYYD 243
+K +EQ+ K WE+E E W K E + ++ + + K +
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 244 GKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFT 303
+ M+ + +E T+ D E +E R ++ K+M EE+ + K
Sbjct: 564 EERMEKKTQEQEKKTW-----DQEEKMREEER---MREREKKMREEEEMMREQEEK---- 611
Query: 304 QMSQYFKAQTEARKQMSKEEKLKIKEE 330
Q K Q + K +EEK++ +EE
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Score = 63.2 bits (152), Expect = 9e-10
Identities = 68/308 (22%), Positives = 142/308 (46%), Gaps = 23/308 (7%)
Query: 25 KDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDR 84
++K +++E + E ++EK R++ + + + EKK +E+EK + +++ ++R
Sbjct: 536 QEKMREQEDQMWE-QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 85 DKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDD 144
+K+ R+EE++ + K+++++E E E+ + K + K E+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEK--------MQEQEEKMWEQEEKMQEQEEKMWEQEEK 646
Query: 145 ADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWK 204
+ +K+ + E+K KL E E + ++ K +++++K+ E ++K KK +EQ+ K
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQ-EQEKMQEQEEKIWE---QEKMEKKTQEQEKK 702
Query: 205 WWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKML 264
W++E+ E + E K E + + + K+ + EE+ KM
Sbjct: 703 TWDQEKMREEESMREREKK----MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMW 758
Query: 265 DHEYTTKEIFRKNFFKD--WRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKE 322
+ E E R K+ W E E++ I K Q K + + K +E
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEK----MRDQEEKMRGQEEKMRGQE 814
Query: 323 EKLKIKEE 330
EK++ +EE
Sbjct: 815 EKMRGQEE 822
Score = 55.5 bits (132), Expect = 2e-07
Identities = 69/351 (19%), Positives = 157/351 (44%), Gaps = 54/351 (15%)
Query: 27 KHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDK 86
+ ++++ R +E + + E+ + ++ EK ++ EK + + E+ K K RD+
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK---KTRDQ 442
Query: 87 EK---------------RKEEKVRASGDAKIKKEKENGFSSP---------PQIKDEPED 122
E+ R+EE+ + K++K++EN + P+ K++ +
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 123 DGYFVPPKEDI-KPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDK 181
+E I + ++ RD+++ + KK+ ++ +E++ ++ E+E+ K +D+
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE------KMRDQ 556
Query: 182 DKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFY 241
++K+ + + + +K K +E++K W +EE+ E + + E K E + +
Sbjct: 557 EQKMWDQEERMEK-KTQEQEKKTWDQEEKMREEERMREREKK----MREEEEMMREQEEK 611
Query: 242 YDGKVMKLSPKAEEVATFFAKMLDHE---YTTKEIFRKNFFKDWRKEMTNEEKNIITNLS 298
+ K+ + E++ KM + E + +E + K W ++ E+K
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE------ 665
Query: 299 KCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKER 349
++ ++ K Q E K +EEK+ +E+ EK +E D K R
Sbjct: 666 -----KLWEHEKMQ-EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Score = 43.1 bits (100), Expect = 0.001
Identities = 42/227 (18%), Positives = 103/227 (45%), Gaps = 49/227 (21%)
Query: 37 EHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEK--RKEEKV 94
EH+K +++EK + + + EK K+ ++ + K EK +++ R++EK R+EE++
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 95 RASGDAKIKKEKENGFSSPPQIKDEPE----------DDGYFVPPKEDIKPLKRPRDEDD 144
+ K+++++E ++ ++ E + KE + ++ ++++
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Query: 145 ADYKPKKIKTEDTK----KEKKRKLEEEEDGKLKK------------------------- 175
+ +K++ ++ K +EK R EE+ G+ +K
Sbjct: 789 IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 176 -----PKNKDKDKKVPEPDNK---KKKPKKEEEQKWKWWEEERYPEG 214
K + +++K+ E + K +++ +E+E+K + EE+ Y G
Sbjct: 849 EEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVG 895
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 66.6 bits (161), Expect = 8e-11
Identities = 68/339 (20%), Positives = 159/339 (46%), Gaps = 34/339 (10%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDG 72
E R + + + K RE K H++EK RE+ E + E+K +E+EK + ++
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE-----EKRQEEEKIREQEKRQEQEA 430
Query: 73 SSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKED 132
+ ++K ++++++ R++EK + KI ++++ Q ++E + +E+
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 133 IKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK--DKDKKVPEPDN 190
I K E + +KI+ ++ K ++ + E++ K+++ + K +++K+ E +
Sbjct: 491 IWRQKEKMHEQE-----EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Query: 191 KKKKPKKEEEQKWKWWEEERYPEGIK-W----KFLEHKGPVFAPPYEPLPENVKFYYDGK 245
++ +K EQ+ W EE+R + K W K E + V+ + + K +
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Query: 246 VM-----KLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSK- 299
M K+ + E++ K+ + E +E ++EMT E++ + +
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIRE----------QEEMTQEQEEKMGEQEEK 655
Query: 300 -CDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKE 337
C+ + Q + +++ +E++ KI+E+ EK+ ++
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Score = 64.3 bits (155), Expect = 4e-10
Identities = 64/319 (20%), Positives = 150/319 (47%), Gaps = 59/319 (18%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K + + E ++ +K ++ E+ H + ++ E+K +E+EK + ++ E+ +
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 434
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
+K + +EEK+R + K+ +++E + +E I+ ++ +++
Sbjct: 435 QEEKIREQEEKIREQ-EKKMWRQEEK------------------IHEQEKIREEEKRQEQ 475
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK--DKDKKVPEPDNKKKKPKKEEE 200
++ + +KI ++ +K K+ E+E+ K++K + K +++K+ E +++K +++EE
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKMHEQEE-KIRKQEEKVWRQEEKIRE---QEEKIREQEE 531
Query: 201 QKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFF 260
+ W+ E+ R E + W+ E K + K+ + + E+
Sbjct: 532 KMWRQEEKIREQEEM-WR-----------------EEEKMHEQEKIWEEEKRQEQE---- 569
Query: 261 AKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMS 320
D + +E R+ K WR+ EEK I + Q + +K + + R+Q
Sbjct: 570 ----DKMWRQEEKIREQEEKVWRQ----EEK--IREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 321 K--EEKLKIKEENEKLLKE 337
K E++ KI+E+ EK+ ++
Sbjct: 620 KIQEQEEKIREQEEKIREQ 638
Score = 56.2 bits (134), Expect = 1e-07
Identities = 35/213 (16%), Positives = 112/213 (52%), Gaps = 13/213 (6%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
+ ++K +++E +E +K ++EK + +K +++EK + ++ + ++K +
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
+++++++++E+ + KI++++E +I+++ E ++ + ++E
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 654
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK---------DKDKKVPEPDNK-- 191
+ + K + E+T ++ K+ E+E K+++ + K ++++K+ E + K
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQEK-KIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 192 -KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHK 223
+++ +E+E+K + EE+ + + ++ + E K
Sbjct: 714 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 53.9 bits (128), Expect = 5e-07
Identities = 36/197 (18%), Positives = 101/197 (51%), Gaps = 24/197 (12%)
Query: 29 KDREHRHKEHKKEKDREKSKHSNSEHKDSEKK-HKEKEKTKHKDGSSEKHKDKHKDRDKE 87
++ + R +E K + EK + + ++ E+K K++EK + ++ ++ ++K ++++++
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 88 KRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADY 147
R++E++ + K+ +++E +++++ E R E+
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE---------------TMWRQEEKIRE 679
Query: 148 KPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK--DKDKKVPEPDNKKKKPKKEEEQKWKW 205
+ KKI+ ++ K ++ ++ +E++ K+ + + K ++++K+ E + K ++ Q+ K
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR------QEEKM 733
Query: 206 WEEERYPEGIKWKFLEH 222
WE+E + K EH
Sbjct: 734 WEQEVRLRQQEEKMQEH 750
Score = 48.9 bits (115), Expect = 2e-05
Identities = 70/341 (20%), Positives = 155/341 (45%), Gaps = 39/341 (11%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHK-EHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
+++++ +L +S K + + +E + K E K ++ + ++H E + +
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFV 127
+ + ++ + +K R+EEK++ + KI++++E +I+++ E
Sbjct: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEE------ 335
Query: 128 PPKEDIKPLKRPRDEDDADYKPKKIKTEDT----KKEKKRKLEE---EEDGKLKKPKNK- 179
K R E+ K +K++ ++ K+EK R+ EE E++ K+++ +
Sbjct: 336 ---------KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 180 -DKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENV 238
+K++K+ E + K + +K EQ+ K EEE+ E + K E + ++ + +
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKMWRQEEKIREQEE 444
Query: 239 KFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLS 298
K K M + EE K+ + E +E R+ + WR+E E+ I
Sbjct: 445 KIREQEKKMW---RQEE------KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 299 KCDFTQMSQYFKAQTEARKQMSK--EEKLKIKEENEKLLKE 337
+ Q + K + + +Q K E++ KI+E+ EK+ ++
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Score = 33.5 bits (75), Expect = 0.76
Identities = 16/114 (14%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKE-KEKT 67
+ +I + + K ++ + +E K ++ E + ++ EKK +E +EK
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPE 121
+ ++ ++ ++K +++++ ++E+ + K+++++E + +++ + E
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 66.2 bits (160), Expect = 1e-10
Identities = 44/197 (22%), Positives = 100/197 (50%), Gaps = 29/197 (14%)
Query: 23 KHKDKHKDREH---RHKEHKKEKDREKSKHSNSEHK---------DSEKKH-----KEKE 65
+ +++ ++RE R KE +EKDRE K + + K D ++K +++E
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 66 KTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGY 125
+ E+ +D+ +++D+E++++ ++ D +I+ EK+ + ++ E + Y
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDR-----DREREMGETERY 172
Query: 126 FVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
+E K + RD D + ++ + ED ++++ R+ E E+D ++ +D+DK
Sbjct: 173 RDRERERQKQRETRRDRD----RERQREKEDRERDRDRQKEREKDRYRERETGRDRDK-- 226
Query: 186 PEPDNKKKKPKKEEEQK 202
E D ++++ K + QK
Sbjct: 227 -ERDRERQREKDRDRQK 242
Score = 60.8 bits (146), Expect = 4e-09
Identities = 34/176 (19%), Positives = 89/176 (50%), Gaps = 18/176 (10%)
Query: 23 KHKDKHKDRE-HRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKH 81
K + + KDRE + ++ ++++DRE+ + + + K +++E + E+ +D+
Sbjct: 74 KERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRK 133
Query: 82 KDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRD 141
+++D+E++++ ++ D +I+ EK+ + ++ E + Y +E K + RD
Sbjct: 134 REKDRERQRQREIGIDKDREIETEKDRD-----REREMGETERYRDRERERQKQRETRRD 188
Query: 142 EDDADYKPKKIKTEDTKKEKKRKLE------------EEEDGKLKKPKNKDKDKKV 185
D + K+ + D ++K+R+ + +E D + ++ K++D+ K +
Sbjct: 189 RDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/209 (17%), Positives = 102/209 (48%), Gaps = 29/209 (13%)
Query: 17 RLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEK 76
R + + + + K+R HR K+ + EKDR++ + + E + + +++E+ +D +E
Sbjct: 62 RQRERERQRKRAKER-HREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETET 120
Query: 77 HKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPL 136
+ + ++R +++++E+ D + ++++E G +I+ E + D
Sbjct: 121 ERQEERERQRDRKREK------DRERQRQREIGIDKDREIETEKDRD------------- 161
Query: 137 KRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEED---GKLKKPKNKDKDK-KVPEPDNKK 192
R R+ + + + + + +++K+R+ + D + K+ + +D+D+ K E D +
Sbjct: 162 -REREMGETE----RYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR 216
Query: 193 KKPKKEEEQKWKWWEEERYPEGIKWKFLE 221
++ + K + E +R + + K ++
Sbjct: 217 ERETGRDRDKERDRERQREKDRDRQKAID 245
Score = 47.0 bits (110), Expect = 7e-05
Identities = 14/89 (15%), Positives = 55/89 (61%), Gaps = 2/89 (2%)
Query: 6 LHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEK-KHKEK 64
+ + + + + ++ +++D+ ++R+ + +E ++++DRE+ + +D ++ K +EK
Sbjct: 154 IETEKDRDREREMGETERYRDRERERQ-KQRETRRDRDRERQREKEDRERDRDRQKEREK 212
Query: 65 EKTKHKDGSSEKHKDKHKDRDKEKRKEEK 93
++ + ++ ++ K++ ++R +EK ++ +
Sbjct: 213 DRYRERETGRDRDKERDRERQREKDRDRQ 241
Score = 40.4 bits (93), Expect = 0.006
Identities = 27/156 (17%), Positives = 73/156 (46%), Gaps = 41/156 (26%)
Query: 62 KEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPE 121
+E+E+ + ++ ++ K++H+++D+E K+ D + K+++E
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDR------DRQRKRDRER------------- 98
Query: 122 DDGYFVPPKEDIKPLKRPRDED-------DADYKPKKIKTEDTKKEKKRKLEEEEDGKLK 174
+R RD D D D + + + E+ ++++ RK E++ + + +
Sbjct: 99 ---------------QRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
Query: 175 KPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEER 210
+ DKD+++ ++ ++ + E ++++ E ER
Sbjct: 144 REIGIDKDREIETEKDRDREREMGETERYRDRERER 179
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 65.5 bits (158), Expect = 2e-10
Identities = 42/180 (23%), Positives = 91/180 (50%), Gaps = 21/180 (11%)
Query: 22 HKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKH 81
H+ +D+ ++RE R + +++K+RE+ + S +D ++ + ++K + + S E+ KDK
Sbjct: 230 HRDRDRDRERERRERSRERDKERERRR---SRSRDRRRRSRSRDKEERR-RSRERSKDKD 285
Query: 82 KDRDKEKRKEEKVRASGDAKIKKEKENG---FSSPPQIKDEPEDDGYFVPPKEDIKPLKR 138
+DR K + + RA + + K+E G + P + D P DDG P ++ P
Sbjct: 286 RDR-KRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDG----PPGELGP--- 337
Query: 139 PRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKE 198
D P++ K D +E++R E + + + +++D+D++ + ++ + E
Sbjct: 338 -----DGPDGPEE-KGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
Score = 37.0 bits (84), Expect = 0.069
Identities = 26/137 (18%), Positives = 54/137 (39%), Gaps = 29/137 (21%)
Query: 2 SGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSN---------- 51
S D + + R + KDK +DR+ R ++ RE+ +
Sbjct: 259 SRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAE 318
Query: 52 -SEHKDS------------------EKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEE 92
SE D+ E+K +++++ + + SE+ + + +DRD+++ +E
Sbjct: 319 PSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREH 378
Query: 93 KVRASGDAKIKKEKENG 109
K G + + E G
Sbjct: 379 KRGERGSERGRDEARGG 395
Score = 36.6 bits (83), Expect = 0.090
Identities = 34/179 (18%), Positives = 77/179 (43%), Gaps = 11/179 (6%)
Query: 25 KDKHKDREHRHKEHKKEKDREKS-KHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKD 83
K K R + E++ E+D + KH++ + D + + E+ + G +
Sbjct: 138 KRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLG 197
Query: 84 RDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDED 143
+ + +R SG + E SP +D D + + +R R E
Sbjct: 198 GTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRD--------RERERRERSR-ER 248
Query: 144 DADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
D + + ++ ++ D ++ + + +EE ++ K+KD+D+K +++ ++E E+K
Sbjct: 249 DKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK-RRSSRSRERARRERERK 306
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 64.7 bits (156), Expect = 3e-10
Identities = 39/200 (19%), Positives = 103/200 (51%), Gaps = 21/200 (10%)
Query: 11 QIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHK 70
Q E +R + ++K ++ E R ++ + + EK + + EK H+++EK + +
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 71 DGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPK 130
+ + ++K D++++ R++E+ + KI++++E +I+++ E
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE--------- 606
Query: 131 EDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDN 190
+ + ++E + + K + E+ +E++ K+ +E+ K ++++KK+ E +
Sbjct: 607 -----MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE------KIREQEKKIREQEE 655
Query: 191 K-KKKPKKEEEQKWKWWEEE 209
K +++ + +EQ+ K WE+E
Sbjct: 656 KIREQEEMMQEQEEKMWEQE 675
Score = 59.3 bits (142), Expect = 1e-08
Identities = 54/329 (16%), Positives = 153/329 (46%), Gaps = 54/329 (16%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K + + E ++ +K ++ E+ H + ++ E+K +E+EK + ++ E+ +
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
+K + +EEK+R + ++E++ + +E I+ ++ +++
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEK-------------------IHEQEKIREEEKRQEQ 522
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK---------DKDKKVPEPDNK-- 191
++ + +KI+ ++ +K K+ E+E+ K++K + K D+++K+ E + K
Sbjct: 523 EEMWRQEEKIREQEEIWRQKEKIHEQEE-KIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 192 ------KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGK 245
+++ +K EQ+ K E+E + + K E + + E + E +
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM-CEQEEKMQEQEE------ 634
Query: 246 VMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQM 305
K+ + E++ K+ + E +E ++ ++ ++M +E+ + C+ +
Sbjct: 635 --KMRRQEEKIREQEKKIREQEEKIRE--QEEMMQEQEEKMWEQEEKM------CEQEEK 684
Query: 306 SQYFKAQTEARKQMSKEEKLKIKEENEKL 334
Q + + +++ E++++++++ EK+
Sbjct: 685 MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Score = 45.4 bits (106), Expect = 2e-04
Identities = 84/470 (17%), Positives = 200/470 (42%), Gaps = 47/470 (10%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHK-EHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
+++++ +L +S K + + +E + K E K ++ + ++H E + +
Sbjct: 284 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 343
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFV 127
+ + ++ + +K R+EEK++ + KI++++E +I+++ E
Sbjct: 344 AQVEENELWNRLNQQQEEKMWRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEE------ 396
Query: 128 PPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPE 187
+ R +++ ++ K E +++++ E+EE + ++ +K++K+ E
Sbjct: 397 ----------KMRRQEEMMWE----KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442
Query: 188 PDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVM 247
+ K + +K EQ+ K EEE+ E K + E K E + E +
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK---MWRQEEKIREQEE-------- 491
Query: 248 KLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQ 307
K+ + E++ K+ + E +E R+ + WR+E E+ I + Q +
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK 551
Query: 308 YFKAQTEARKQMSK--EEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRG 365
K + + +Q K +++ KI+E+ EK+ ++ K R KI
Sbjct: 552 IRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR--------- 602
Query: 366 NHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIK 425
+M + M E C ++ K+ + +E + + + E I+ +
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 426 YIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQR 475
M+ E++ + E ++++ +K+R Q + W+ +E+++RQ+
Sbjct: 663 --MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE-QEVRLRQQ 709
Score = 40.0 bits (92), Expect = 0.008
Identities = 29/154 (18%), Positives = 78/154 (50%), Gaps = 7/154 (4%)
Query: 22 HKHKDKHKDREHR--HKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT--KHKDGSSEKH 77
H ++K +++E + +E K + EK + + ++ E+ +E+E+ + ++ E+
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 78 KDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLK 137
+ + +K +R+EEK+R + KI +E+E ++ E E+ + K + K
Sbjct: 627 EKMQEQEEKMRRQEEKIREQ-EKKI-REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Query: 138 RPRDEDDADYKPKKIKTEDTK-KEKKRKLEEEED 170
E+ + +K+ ++ + ++++ K++E ++
Sbjct: 685 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 64.3 bits (155), Expect = 4e-10
Identities = 50/218 (22%), Positives = 110/218 (50%), Gaps = 21/218 (9%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKEKDREK-SKHSNSEHKDSEKKHKEKEKTKHKD 71
E + ++++ K +++ + R+ K ++EK +E+ +K E K E++ K +E+ K
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 72 GSSEKHKDKHKDRDKEK--------RKEEKVRASGD-----------AKIKKEKENGFSS 112
EK ++ K R++EK R+EEK+R + KI+K++E +
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500
Query: 113 PPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGK 172
++ D+ E + R ++E + + K + E+ +E++ K+ E+E+
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 173 LKKPKNKDKDKKVPEPDNK-KKKPKKEEEQKWKWWEEE 209
++ K + +++K+ E + K +++ +K EQ+ K WE+E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Score = 59.3 bits (142), Expect = 1e-08
Identities = 40/191 (20%), Positives = 105/191 (54%), Gaps = 28/191 (14%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
+ ++K +++E ++ +K +++E+ + + EK K++EK ++ + H + K
Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE--EKMHDQEEK 510
Query: 83 DRDKEK---RKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRP 139
R++E+ R+EEK+R + KI++++E +I+++ E + +
Sbjct: 511 IREQEEKMWRQEEKIREQ-EEKIREQEE-------KIREQEE--------------MMQE 548
Query: 140 RDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNK-KKKPKKE 198
++E + + K + E ++++++ E+EE + +K K +++++K+ E + K +++ +
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608
Query: 199 EEQKWKWWEEE 209
+EQ+ K WE+E
Sbjct: 609 QEQEEKMWEQE 619
Score = 56.6 bits (135), Expect = 8e-08
Identities = 55/308 (17%), Positives = 137/308 (44%), Gaps = 27/308 (8%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K + + E ++ +K ++ E+ H + ++ E+K +E+EK + ++ E+ +
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 420
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
+K + +EEK+R + K+ +++E + +E I+ ++ +++
Sbjct: 421 QEEKIREQEEKIREQ-EKKMWRQEEK------------------IHEQEKIREEEKRQEQ 461
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
++ + +KI+ ++ +K K+ E+E + ++ K +++K+ ++++K +++EE+
Sbjct: 462 EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM---HDQEEKIREQEEKM 518
Query: 203 WKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAK 262
W+ E+ R E K E + + + K + M+ K +
Sbjct: 519 WRQEEKIREQEE---KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE 575
Query: 263 MLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKE 322
+ KE R+ K W +E E+ + + + + Q K + K +E
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEM--MQEQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 323 EKLKIKEE 330
EK++ +EE
Sbjct: 634 EKMRRQEE 641
Score = 51.2 bits (121), Expect = 4e-06
Identities = 38/180 (21%), Positives = 95/180 (52%), Gaps = 19/180 (10%)
Query: 23 KHKDKHKDREH--RHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEK-TKHKDGSSEKHKD 79
+ ++K D+E R +E K + EK + + ++ E+K +E+E+ + ++ + ++
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
Query: 80 KHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRP 139
K ++++K +R+EEK+R + KI+++KE +I ++ E R
Sbjct: 559 KMQEQEKMRRQEEKIREQ-EEKIREQKEKIREQEEKIWEQEEK--------------IRE 603
Query: 140 RDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEE 199
++E + + K + E+ E++ K++E+E+ K+++ + K +++V ++K + +E
Sbjct: 604 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE-KMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 49.7 bits (117), Expect = 1e-05
Identities = 91/477 (19%), Positives = 203/477 (42%), Gaps = 56/477 (11%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHK-EHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
+++++ +L +S K + + +E + K E K ++ + ++H E + +
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
Query: 68 KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFV 127
+ + ++ + +K R+EEK++ + KI++++E +I+++ E
Sbjct: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEE------ 335
Query: 128 PPKEDIKPLKRPRDEDDADYKPKKIKTEDT----KKEKKRKLEEEEDGKLKKPKNKDKDK 183
K R E+ K +K++ ++ K+EK R+LEE +K++
Sbjct: 336 ---------KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE---------MMWEKEE 377
Query: 184 KVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYD 243
K+ E + K + +K EQ+ K EEE+ E + K E + ++ + + K
Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 244 GKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFT 303
K M + EE K+ + E +E R+ + WR+E E+ I +
Sbjct: 436 EKKMW---RQEE------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE---- 482
Query: 304 QMSQYFKAQTEARKQMSKEEKL-----KIKEENEKLLKEYGFCIMDNHKERIANFKIEPP 358
+M + K + + K +EEK+ KI+E+ EK+ ++ K R KI
Sbjct: 483 KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542
Query: 359 GLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTE 418
+ KMG + ++ ++ + + + + +++R + W E
Sbjct: 543 EEMM-QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW--EQEE 599
Query: 419 NIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQR 475
I+ + M+ E++ + E ++++ +K+R Q + W+ +E+++RQ+
Sbjct: 600 KIREQEE--MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE-QEVRLRQQ 653
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 64.3 bits (155), Expect = 4e-10
Identities = 44/209 (21%), Positives = 115/209 (55%), Gaps = 20/209 (9%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDG 72
E R + + + K RE K H++EK RE+ E + E+K +E+EK + ++
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-----EEKRQEEEKIREQEKRQEQEA 383
Query: 73 SSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKED 132
+ ++K ++++++ R++E++ + K+ +++E + +++++ E +E
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK---MRRQEEK 440
Query: 133 IKPL-KRPRDEDDADYKPKKIKTEDTKK---------EKKRKLEEEEDG-KLKKPKNKDK 181
I+ K+ R++++ + +++ E +K E++ K++E+E+ + ++ K +++
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 182 DKKVPEPDNK-KKKPKKEEEQKWKWWEEE 209
+KK+ E + K +++ + +EQ+ K WE+E
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Score = 53.5 bits (127), Expect = 7e-07
Identities = 60/339 (17%), Positives = 156/339 (46%), Gaps = 35/339 (10%)
Query: 4 DHLHNDSQ-----IEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSE 58
DHL + Q ++A N+ ++ ++ + +E K ++ EK + + ++ E
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315
Query: 59 KKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKD 118
+K + +E+ EK + + + KEEK+R + ++EK Q +
Sbjct: 316 EKMRRQEEMMW-----EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR-----EQEEK 365
Query: 119 EPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIK-TEDTKKEKKRKLEEEEDGKLKKPK 177
E++ K + K R E+ + +KI+ E+ +E++ K+ E+E+ ++ +
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 178 N-KDKDKKVPEPDNK-KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLP 235
+++++K+ + K +++ KK EQ+ K E+E + + K E +G +
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM-------CE 478
Query: 236 ENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIIT 295
+ K + K+ + E++ K+ + E +E ++ ++ ++M +E+ +
Sbjct: 479 QEAKMQEQEE--KMRRQEEKIREQEKKIREQEEKIRE--QEEMMQEQEEKMWEQEEKM-- 532
Query: 296 NLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKL 334
C+ + Q + + +++ +E++++++++ EK+
Sbjct: 533 ----CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 50.4 bits (119), Expect = 6e-06
Identities = 56/321 (17%), Positives = 144/321 (44%), Gaps = 38/321 (11%)
Query: 30 DREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKR 89
+ +H KE + + +++ +E + + +E++ + ++ E+ + + +K +
Sbjct: 254 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 90 KEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKP 149
+EEK+R ++ EKE ++ E E+ + R+ ++ ++
Sbjct: 314 QEEKMRR--QEEMMWEKEEKMRRQEEMMWEKEE---------------KIRELEEKMHEQ 356
Query: 150 KKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNK--------KKKPKKEEEQ 201
+KI+ ++ K++++ K+ E+E + ++ K +++K+ E + K +++ +K EQ
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 202 KWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFA 261
+ K WE+E + + K + + + + K ++M+ + E++
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ--EQEEKMGEQEG 474
Query: 262 KMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSK 321
KM + E +E ++ + +++ +EK I K Q Q + K +
Sbjct: 475 KMCEQEAKMQE--QEEKMRRQEEKIREQEKKIREQEEKI----REQEEMMQEQEEKMWEQ 528
Query: 322 EEKL-----KIKEENEKLLKE 337
EEK+ K++E+ EK+ ++
Sbjct: 529 EEKMCEQEEKMQEQEEKMRRQ 549
Score = 40.0 bits (92), Expect = 0.008
Identities = 69/322 (21%), Positives = 142/322 (44%), Gaps = 44/322 (13%)
Query: 50 SNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRK----EEKVRASGDAKIKKE 105
++ E K+ K +EK + + S + K R E+ K +++++A D + KE
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKE 261
Query: 106 KENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTK----KEK 161
++ + +E E +E+ K R E+ + +KI+ ++ K +EK
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEE----KMWRQEEKIQEREEKIQEQEEKIREQEEK 317
Query: 162 KRKLEE---EEDGKLKKPKNK--DKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIK 216
R+ EE E++ K+++ + +K++K+ E + K + +K EQ+ K EEE+ E +
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--Q 375
Query: 217 WKFLEHKGPVFAPPYEPLPENVKFYYDGKVM------------KLSPKAEEVATFFAKML 264
K E + ++ + + K ++M K+ + EE+ KM
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 265 DHEYTTKEIFRKNFFKDWR----KEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMS 320
E +E +K ++ + +EM E++ + + + Q K Q + K
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEE---KMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 321 KEEKL-----KIKEENEKLLKE 337
+EEK+ KI+E+ EK+ ++
Sbjct: 493 QEEKIREQEKKIREQEEKIREQ 514
Score = 36.6 bits (83), Expect = 0.090
Identities = 28/144 (19%), Positives = 72/144 (50%), Gaps = 5/144 (3%)
Query: 27 KHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKE-KEKTKHKDGS-SEKHKDKHKDR 84
+ ++ + R +E K + +K + + ++ E+ +E +EK ++G E+ +
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 85 DKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDD 144
+K +R+EEK+R + KI +E+E ++ E E+ + K + K E+
Sbjct: 488 EKMRRQEEKIREQ-EKKI-REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Query: 145 ADYKPKKIKTEDTK-KEKKRKLEE 167
+ +K++ ++ + ++++ K++E
Sbjct: 546 MRRQEEKMREQEVRLRQQEEKMQE 569
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 64.3 bits (155), Expect = 4e-10
Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 30/150 (20%)
Query: 36 KEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKD-KHKDRDKEKRKEEKV 94
K+ KK+K+ E+++ + ++ EK+ K KEK K K EK K K ++ KEK +EEK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 95 RASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKT 154
R K K+E+E ++E E++ +E++ + + K+
Sbjct: 62 RKRKRKKKKEEEE---------REEEEEE-----------------EEEEKEEEEKEEGR 95
Query: 155 EDTKKEKKRKLEEEEDGKLKKPKNKDKDKK 184
KK+K+R+ EEEE+ KK K + K KK
Sbjct: 96 RRKKKKKRRRKEEEEE---KKKKRRRKTKK 122
Score = 62.4 bits (150), Expect = 2e-09
Identities = 45/161 (27%), Positives = 76/161 (47%), Gaps = 39/161 (24%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
K K K K+ E + + E++ EK + K+ K+ ++K+KTK +EK K+K +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK----ETEKRKEKEE 57
Query: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
+ K KRK +K KKE+E ++E E+ +E
Sbjct: 58 EEKKRKRKRKK---------KKEEEE--------REEEEE------------------EE 82
Query: 143 DDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDK 183
++ + +K + KK+KKR+ +EEE+ K KK + K K K
Sbjct: 83 EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 55.1 bits (131), Expect = 2e-07
Identities = 45/153 (29%), Positives = 78/153 (50%), Gaps = 35/153 (22%)
Query: 55 KDSEKKHKEKEKTKHKDGSSEKHKD--KHKDRDKEKRKE-EKVRASGDAKIKKEKENGFS 111
K +KK KE E+T+ + + E+ + K K++ KEKRKE EK + + + + +KEKE
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56
Query: 112 SPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDG 171
E+ K KR R K KK + E ++E++ + E+EE+
Sbjct: 57 -------------------EEEKKRKRKR-------KKKKEEEEREEEEEEEEEEKEEEE 90
Query: 172 KL--KKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
K ++ K K K ++ E + KKKK +++ ++K
Sbjct: 91 KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 53.5 bits (127), Expect = 7e-07
Identities = 21/87 (24%), Positives = 51/87 (58%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKD 79
++ + ++K R+ + KE +KEK+++K + K+ E++ K++++ + K E+ ++
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 80 KHKDRDKEKRKEEKVRASGDAKIKKEK 106
+ ++ ++EK +EEK K KK +
Sbjct: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Score = 51.2 bits (121), Expect = 4e-06
Identities = 20/98 (20%), Positives = 56/98 (57%)
Query: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTK 68
+ + E + + + K K K K+++ + KE +K K++E+ + + +K+ +E+E+ +
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79
Query: 69 HKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEK 106
++ ++ ++K + R ++K+K+ + + + K KK +
Sbjct: 80 EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 3/79 (3%)
Query: 134 KPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKK 193
K K+ +E + + ++ + ++ K+++KRK + +E K KK K +K K+ E + K+K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 194 ---KPKKEEEQKWKWWEEE 209
K KKEEE++ + EEE
Sbjct: 64 RKRKKKKEEEEREEEEEEE 82
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 16/82 (19%)
Query: 148 KPKKIKTEDTKKEKKRKLEEEEDGKLK-----KPKNKDKDKKVPEPDNKK---------- 192
K KK +TE+T++ ++ + EEE++GK K K K K+K KK E + +K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 193 -KKPKKEEEQKWKWWEEERYPE 213
K+ KK+EE++ + EEE E
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEE 85
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/92 (28%), Positives = 52/92 (56%), Gaps = 8/92 (8%)
Query: 131 EDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKK----PKNKDKDKKVP 186
E+ + + +E++ + K K+ + E K+++K+K +E + + +K K K K KK
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 187 EPDNKKKKPKKEEEQKWKWWEEERYPEGIKWK 218
E + ++++ ++EEE+K EEE EG + K
Sbjct: 71 EEEEREEEEEEEEEEK----EEEEKEEGRRRK 98
Score = 39.7 bits (91), Expect = 0.011
Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 16/63 (25%)
Query: 158 KKEKKRKL-------------EEEEDGKLK---KPKNKDKDKKVPEPDNKKKKPKKEEEQ 201
KK+KK+K EEE++GK K K K K+K+KK + +K+K K+EEE+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 202 KWK 204
K K
Sbjct: 61 KRK 63
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 64.3 bits (155), Expect = 4e-10
Identities = 53/199 (26%), Positives = 94/199 (47%), Gaps = 25/199 (12%)
Query: 25 KDKHKDREHRHKEHKKE-KDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKD 83
K++ K E K+E K EK+K E S +K K EK K D S + K K+
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Query: 84 RDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIK-PLK----- 137
+ + +K + +K+E ++ + +K++ + +P KE++K P+K
Sbjct: 773 --EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830
Query: 138 ---------RPRDEDDADYKPKKIKTEDTKKEK-------KRKLEEEEDGKLKKPKNKDK 181
+ +E+ A PK + +D+KKE+ K K+EE+++ ++KPK
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890
Query: 182 DKKVPEPDNKKKKPKKEEE 200
+ K E ++KKK P E+E
Sbjct: 891 EAKKEEAEDKKKVPTPEKE 909
Score = 63.2 bits (152), Expect = 9e-10
Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 35/199 (17%)
Query: 25 KDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDR 84
K++ K +E + KE K+ + EK+ + K EKK +KE+ K+ K ++K K+
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAP---ATPKTEEKKDSKKEEAPKKEAPKPKVEEK-KEP 880
Query: 85 DKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRP----R 140
EK KE KV A K+E E+ P K+ P V KED KP ++ +
Sbjct: 881 AVEKPKESKVEAK-----KEEAEDKKKVPTPEKEAPAK----VEVKEDAKPKEKTEVAKK 931
Query: 141 DEDDADYKPKKIKTE---------DTKKEKKRKLEE---------EEDGKLKKPKNKDKD 182
+ DDA K E DTK+EK +K EE E+D L K +K K
Sbjct: 932 EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Query: 183 KKVPEPDNKKKKPKKEEEQ 201
+K + + +K K E+
Sbjct: 992 EKAEKSSSTDQKDSKPPEK 1010
Score = 57.4 bits (137), Expect = 5e-08
Identities = 74/300 (24%), Positives = 112/300 (37%), Gaps = 26/300 (8%)
Query: 42 KDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRK---EEKVRASG 98
K EK+K E S +K K K + K K K + + EK K +E+ ++
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 99 DAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTK 158
AK ++ + P+ K +++ K K ++E + K K ED K
Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808
Query: 159 KEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPK-----KEEEQKWKWWEEERYPE 213
+K ++EE K + K ++ KV EP K ++ K K EE+K EE E
Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868
Query: 214 GIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEI 273
K K E K P P E E K + K +P+ E A K E+
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 274 FRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEK 333
+K KE + + K + K+ +KEEK K EE K
Sbjct: 929 AKKEPDDAKAKEPSKPAE------------------KKEAAPEKKDTKEEKAKKPEEKPK 970
Score = 53.9 bits (128), Expect = 5e-07
Identities = 74/338 (21%), Positives = 124/338 (36%), Gaps = 20/338 (5%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKE-KDREKSKHSNSEHKDSEKKHKEKEKTKHKD 71
EA + + K + K E + E K EK+K E S + K EK + K
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 72 GSSEKHKDKHKDRDKEKRK---EEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVP 128
+ K +K K KE+ K E K + +K+E ++ + +K+E +
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 129 PKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKR-KLEEEEDGKLKKPKNKDKDKKVPE 187
P++ P K + P+K + + +K K K E + K K P +
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 188 PDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVM 247
K++ K E+ K EE + PE + K PV P + K
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPE-------KAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Query: 248 KLSPKAEEVATFFAKMLDHEYTTKEIFRK--NFFKDWRKEMTNEEKNIITNLS---KCDF 302
+ + E+ T K + + KE R + F + K EE K D
Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA 807
Query: 303 TQMSQYFKAQTEARKQMSKEEK---LKIKEENEKLLKE 337
+ + E + + +EEK +K+KE +K +E
Sbjct: 808 KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Score = 53.9 bits (128), Expect = 5e-07
Identities = 75/272 (27%), Positives = 113/272 (41%), Gaps = 42/272 (15%)
Query: 10 SQIEADFRLNDSHKHKDKHKDREHRHKEHK---KEKDR-------EKSKHSNSEHKDSEK 59
S ++ + + + K +K K + + E K KE+ R EK+K E S +
Sbjct: 738 SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 60 KHKEKEKTKHKDGSSE---KHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQI 116
K K K K E K + K +++EK +E KV+ KK +E + P+
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP----KKAEEEKAPATPKT 853
Query: 117 KDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKL-----EEEEDG 171
+++ + P KE KP K ++ A KPK+ K E K+E + K E+E
Sbjct: 854 EEKKDSKKEEAPKKEAPKP-KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912
Query: 172 KLK-----KPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPV 226
K++ KPK K + K D K K+P K E+K E PE K + K P
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK------EAAPEKKDTKEEKAKKPE 966
Query: 227 FAPPYEPLPENVKFYYDGKVMK---LSPKAEE 255
P E K D K + PKAE+
Sbjct: 967 EKPKTE-----AKAKEDDKTLSKEPSKPKAEK 993
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/184 (28%), Positives = 69/184 (37%), Gaps = 27/184 (14%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKD 79
DS K + K+ E KKE EK K S E KK + +D
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE----AKKEEA--------------ED 899
Query: 80 KHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIK-DEPEDDGYFVPPKEDIKPLKR 138
K K EK KV DAK K++ E P K EP K++ P K+
Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA----EKKEAAPEKK 955
Query: 139 PRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKE 198
E+ A +K KTE KE + L +E KPK + +K K P+K
Sbjct: 956 DTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP----SKPKAEKAEKSSSTDQKDSKPPEKA 1011
Query: 199 EEQK 202
E K
Sbjct: 1012 TEDK 1015
Score = 45.4 bits (106), Expect = 2e-04
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 19/203 (9%)
Query: 27 KHKDREHRHKEHKKEKD----REKSKHSNSEHKDSEKKHKE--KEKTKHKDGSSEKHKDK 80
K K E K EK+ E+++ + + +E++ KE +E+ K ++G E+ +
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496
Query: 81 HKDRDKEKRKEEKVRASGDAK--IKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKR 138
++ K EE +AK +K+E ++ + K+E + P++ P K
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK- 555
Query: 139 PRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKE 198
+E + + K + E+ K + K E+ K+ + K PE K K P KE
Sbjct: 556 --EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE---KAKSPVKE 610
Query: 199 E-----EQKWKWWEEERYPEGIK 216
E E K EE + P +K
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVK 633
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/188 (22%), Positives = 74/188 (39%), Gaps = 15/188 (7%)
Query: 27 KHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDK 86
+ +++E + +E K+E+ E+ + E + +E + + S K + K K
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 87 EKRKEEK---VRASGDAKIKKEKENGFSSPPQIK----DEPEDDGYFVPPKEDIKPLKRP 139
KEE K K + SPP+ K +E + P++ P K
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591
Query: 140 RDEDDADYKPKKIKT---EDTKKEKKRKLEEEEDGK----LKKP-KNKDKDKKVPEPDNK 191
P+K K+ E+ K + K +E+ K +K P K K K+ + K
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651
Query: 192 KKKPKKEE 199
K P+KEE
Sbjct: 652 AKSPEKEE 659
Score = 43.5 bits (101), Expect = 7e-04
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 15/189 (7%)
Query: 40 KEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGD 99
+E E+ K + E E+ +E+E ++ + ++ +KE + K A
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527
Query: 100 AKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIK---PLKRPRDED---DADYK-PKKI 152
A+ K ++ SP ++K + P KE+ K K P E+ A+ K P+K
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKS---PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 153 KT---EDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKK--KPKKEEEQKWKWWE 207
K+ E+ K + K E+ +K+ + K P + K + K E+ K E
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Query: 208 EERYPEGIK 216
E + PE K
Sbjct: 645 EAKSPEKAK 653
Score = 30.4 bits (67), Expect = 6.4
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 634 RAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQR 693
+ PPK E+ K + KK+ +K + K+A KV E K+ AV++
Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKD-----------SKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 694 LEEQLMKLEVQATDREENKQI 714
+E K+E + + E+ K++
Sbjct: 885 PKES--KVEAKKEEAEDKKKV 903
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 63.9 bits (154), Expect = 5e-10
Identities = 55/212 (25%), Positives = 98/212 (46%), Gaps = 23/212 (10%)
Query: 2 SGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRH------KEHKKEKDREKSKHSNSEHK 55
S D + +++ + + +D K KD KD E K+ +K+ ++K K + K
Sbjct: 303 SKDAKKDSKKVKKNVKKDD--KKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKK 360
Query: 56 DSEKKHKEKEKTKHKDGSSEKHKDKH-----KDRDKEKRKEEKVRASGDAKIKKEKENGF 110
KK+ E T+ D ++ ++ K+ DK K+ +K+ S D+ + E E+
Sbjct: 361 KDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDK-KKDAKKITFSTDS--ESELESKE 417
Query: 111 SSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEED 170
S + KD+ + ++ K +K + DAD +PK + K EKK K + ++D
Sbjct: 418 SQKDEKKDKKDS------KTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKD 471
Query: 171 GKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
K KK K+ + E D + KK KK ++K
Sbjct: 472 DK-KKDAKKNAESTEMESDLELKKDKKHSKEK 502
Score = 62.0 bits (149), Expect = 2e-09
Identities = 53/212 (25%), Positives = 87/212 (41%), Gaps = 21/212 (9%)
Query: 8 NDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT 67
+D I D L + ++ K+ ++ K KK+ + K S++E +DS+ K+ +K
Sbjct: 255 DDESINFDAWLRNYSQNNSKNYSLKYT-KYTKKDTKKNAKKSSDAESEDSKDAKKDSKKV 313
Query: 68 KHKDGSSEKHKDKHKDRDK------EKRKEEKVRASGDAKIKKE-KENGFSSPPQIKDEP 120
K +K KD KD + + + E K K+KK+ K+ P+ D
Sbjct: 314 KKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTE 373
Query: 121 EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKI-----------KTEDTKKEKKRKLEEEE 169
D + D + LK+ DD KKI E K EKK K + +
Sbjct: 374 SGDAK--DARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKT 431
Query: 170 DGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQ 201
D K +++ EP KK KK+E++
Sbjct: 432 DNKKSVKNDEESTDADSEPKGDSKKGKKDEKK 463
Score = 57.8 bits (138), Expect = 4e-08
Identities = 54/199 (27%), Positives = 87/199 (43%), Gaps = 21/199 (10%)
Query: 13 EADFRLNDSHKHKDKHKDREHRHKEHKKE-KDREKSKHSNSEHKDSEKKHKEKEKTKHKD 71
+++ L KD+ KD++ ++KK K+ E+S ++SE K KK K+ EK KD
Sbjct: 408 DSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKD 467
Query: 72 GSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKE 131
K DK KD K+ E D ++KK+K++ KD +D ++
Sbjct: 468 ---SKKDDKKKD---AKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKD------ARK 515
Query: 132 DIKPLKRPRDEDD-ADYKPK-KIKTEDTKKEKK------RKLEEEEDGKLKKPKNKDKDK 183
D + DE +K KIK DT+ E+ +K +E DG K + +
Sbjct: 516 DTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLES 575
Query: 184 KVPEPDNKKKKPKKEEEQK 202
K + KK E+ +K
Sbjct: 576 KRGFRMSSKKTTFNEKGEK 594
Score = 51.6 bits (122), Expect = 3e-06
Identities = 78/325 (24%), Positives = 122/325 (37%), Gaps = 19/325 (5%)
Query: 44 REKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIK 103
+ SK+ + ++ KK +K K D SE KD KD K K+ +K D +K
Sbjct: 270 QNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKD--VK 327
Query: 104 KEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKR 163
K+ E+ + KDE +D K+D K LK+ + D P+ TE + R
Sbjct: 328 KDTESTDAESGDSKDERKDT------KKDKKKLKKDDKKKDTKKYPESTDTESGDAKDAR 381
Query: 164 KLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKW---KFL 220
+ LKK D KK + + E E K +E++ + K K +
Sbjct: 382 N----DSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSV 437
Query: 221 EHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFK 280
++ EP ++ K D K K K ++ K + ++ K K
Sbjct: 438 KNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKK-DK 496
Query: 281 DWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGF 340
KE +K+I + K D F ++ + S + K E E L K
Sbjct: 497 KHSKEKKGSKKDIKKDARK-DTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAK 555
Query: 341 CIMDNHKERIANFKIEPPGLFRGRG 365
+D AN K+E GL RG
Sbjct: 556 KKIDESDGTSANSKME--GLESKRG 578
Score = 51.2 bits (121), Expect = 4e-06
Identities = 74/262 (28%), Positives = 102/262 (38%), Gaps = 43/262 (16%)
Query: 2 SGD--HLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEK 59
SGD NDS+ L + K+ DK KD K+ D E S KD EK
Sbjct: 374 SGDAKDARNDSR-----NLKKASKNDDKKKDA----KKITFSTDSESELESKESQKD-EK 423
Query: 60 KHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDE 119
K K+ KT +K S K+ ++ D D E + + K K KK+++ G KD
Sbjct: 424 KDKKDSKTDNK--KSVKNDEESTDADSEPKGDSK-------KGKKDEKKG------KKDS 468
Query: 120 PEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNK 179
+DD K+D K E ++D + KK KK K K ++D +KK K
Sbjct: 469 KKDD-----KKKDAKK-NAESTEMESDLELKK-----DKKHSKEKKGSKKD--IKKDARK 515
Query: 180 DKDKKVPEPDNKKK---KPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPE 236
D + E D K K + + EE Y G K K E G E L
Sbjct: 516 DTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLES 575
Query: 237 NVKFYYDGKVMKLSPKAEEVAT 258
F K + K E+ +T
Sbjct: 576 KRGFRMSSKKTTFNEKGEKAST 597
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/232 (24%), Positives = 92/232 (39%), Gaps = 42/232 (18%)
Query: 2 SGDHLHNDSQIEADFRLNDSHKHK-----DKHKDREHRHKEHKKEKDREKSKHSNSE--- 53
S + +SQ N S K K K + E H ++ +KD ++SK SN
Sbjct: 177 SSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISE 236
Query: 54 ----------------HKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRAS 97
D E + + + +S+ + K+ K+ K + + S
Sbjct: 237 ICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTK-KNAKKS 295
Query: 98 GDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYK--------- 148
DA+ + K+ S K+ +DD K+D+K D + D K
Sbjct: 296 SDAESEDSKDAKKDSKKVKKNVKKDD-----KKKDVKKDTESTDAESGDSKDERKDTKKD 350
Query: 149 PKKIKTEDTKKEKKRKLE--EEEDGKLKKPKNKDKD-KKVPEPDNKKKKPKK 197
KK+K +D KK+ K+ E + E G K +N ++ KK + D+KKK KK
Sbjct: 351 KKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKK 402
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/205 (24%), Positives = 78/205 (38%), Gaps = 28/205 (13%)
Query: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSE------- 75
K K K + K+ EK+K N K K E E++K SSE
Sbjct: 128 KKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQN 187
Query: 76 --------KHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPED----D 123
KDK ++ +K E + + K K K + S+ P + E+ D
Sbjct: 188 SKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPK-KDLKRSKTSNDPISEICSENSLNVD 246
Query: 124 GYFVPPKEDIKP------LKRPRDEDDADYKPK--KIKTEDTKKEKKRKLEEEEDGKLKK 175
+ + D + L+ + +Y K K +DTKK K+ + E +
Sbjct: 247 FLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDA 306
Query: 176 PKNKDKDKKVPEPDNKKKKPKKEEE 200
K+ K KK + D+KKK KK+ E
Sbjct: 307 KKDSKKVKKNVKKDDKKKDVKKDTE 331
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/227 (24%), Positives = 86/227 (37%), Gaps = 46/227 (20%)
Query: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSE----KKHKEKEKTKHKDGSSE 75
DS K K K + K+ K+KD +K+ S D E KKH KEK
Sbjct: 453 DSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHS-KEK--------- 502
Query: 76 KHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIK--DEPEDDGYFVPPKEDI 133
K KD K+ RK+ + S DA+ + + GF + +IK D ++ + P
Sbjct: 503 --KGSKKDIKKDARKDTE---STDAEFDESSKTGFKTSTKIKGSDTESEESLYKP----- 552
Query: 134 KPLKRPRDEDDADYKPKKIKTEDTKK----EKKRKLEEEEDGKLKKPKNKDKDKKVPEPD 189
K+ DE D K++ ++K+ K+ E+ K + +K P P
Sbjct: 553 -GAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPLPA 611
Query: 190 NKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPE 236
+ P P+ + + + P P Y PLPE
Sbjct: 612 CEPSLPS---------------PKVRRLCWCKMPPPPPKPRYAPLPE 643
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,974,926
Number of Sequences: 37866
Number of extensions: 1792951
Number of successful extensions: 34559
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 898
Number of HSP's that attempted gapping in prelim test: 10288
Number of HSP's gapped (non-prelim): 11161
length of query: 765
length of database: 18,247,518
effective HSP length: 110
effective length of query: 655
effective length of database: 14,082,258
effective search space: 9223878990
effective search space used: 9223878990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.