Guide to the Human Genome
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Name: TOP1MT Sequence: fasta or formatted (601aa) NCBI GI: 16418461
Description:

mitochondrial topoisomerase I

Referenced in:

Mitochondria
Replication Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         50           3
 C cysteine            1.7         10           2
 D aspartate           5.0         30           2
 E glutamate           9.5         57           2
 F phenylalanine       4.2         25           2
 G glycine             5.0         30           1
 H histidine           2.2         13           1
 I isoleucine          3.5         21           1
 K lysine              8.7         52           2
 L leucine             8.7         52           2
 M methionine          1.8         11           1
 N asparagine          3.2         19           1
 P proline             4.0         24           2
 Q glutamine           4.8         29           2
 R arginine            9.8         59           2
 S serine              4.5         27           1
 T threonine           4.5         27           3
 V valine              6.3         38           2
 W tryptophan          1.7         10           1
 Y tyrosine            2.8         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitochondrial topoisomerase I 
TOP1                  0.705   DNA topoisomerase I 
GOLGB1                0.018   golgi autoantigen, golgin subfamily b, macrogolgin ...
SMC2                  0.013   structural maintenance of chromosomes 2 
SMC2                  0.013   structural maintenance of chromosomes 2 
SMC2                  0.013   structural maintenance of chromosomes 2 
ANKRD20A1             0.012   ankyrin repeat domain 20 family, member A1 
GBP7                  0.011   guanylate binding protein 4-like 
ANKRD20A4             0.011   ankyrin repeat domain 20 family, member A4 
MYH10                 0.011   myosin, heavy polypeptide 10, non-muscle 
PLEC1                 0.011   plectin 1 isoform 11 
PLEC1                 0.011   plectin 1 isoform 10 
PLEC1                 0.011   plectin 1 isoform 8 
PLEC1                 0.011   plectin 1 isoform 7 
PLEC1                 0.011   plectin 1 isoform 6 
PLEC1                 0.011   plectin 1 isoform 3 
PLEC1                 0.011   plectin 1 isoform 2 
PLEC1                 0.011   plectin 1 isoform 1 
ANKRD20A3             0.010   ankyrin repeat domain 20 family, member A3 
SMC3                  0.010   structural maintenance of chromosomes 3 
CENPE                 0.010   centromere protein E 
ANKRD20A2             0.010   ankyrin repeat domain 20 family, member A2 
HOMER3                0.010   Homer, neuronal immediate early gene, 3 isoform 2 [...
CNTROB                0.010   centrobin, centrosomal BRCA2 interacting protein is...
CNTROB                0.010   centrobin, centrosomal BRCA2 interacting protein iso...
GOLGA8B               0.010   golgi autoantigen, golgin subfamily a, 8B 
GOLGA8A               0.010   golgi autoantigen, golgin subfamily a, 8A 
LOC283685             0.010   PREDICTED: golgi autoantigen, golgin subfamily a-li...
MCM10                 0.010   minichromosome maintenance complex component 10 isof...
CROCC                 0.010   ciliary rootlet coiled-coil 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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