BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo sapiens] (1687 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho... 3413 0.0 gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom... 3355 0.0 gi|40807471 transcription termination factor, RNA polymerase II ... 113 1e-24 gi|21071052 helicase-like transcription factor [Homo sapiens] 111 7e-24 gi|21071054 helicase-like transcription factor [Homo sapiens] 111 7e-24 gi|58331268 excision repair protein ERCC6-like [Homo sapiens] 80 1e-14 gi|21914927 helicase, lymphoid-specific [Homo sapiens] 74 9e-13 gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 74 9e-13 gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 69 3e-11 gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo s... 69 3e-11 gi|58219008 RAD26L hypothetical protein [Homo sapiens] 67 1e-10 gi|21071058 SWI/SNF-related matrix-associated actin-dependent re... 66 3e-10 gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 65 7e-10 gi|164419749 SWI/SNF-related matrix-associated actin-dependent r... 65 7e-10 gi|21071044 SWI/SNF-related matrix-associated actin-dependent re... 65 7e-10 gi|38708321 INO80 complex homolog 1 [Homo sapiens] 64 1e-09 gi|4557565 excision repair cross-complementing rodent repair def... 64 2e-09 gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 63 3e-09 gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 63 3e-09 gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 63 3e-09 gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 62 4e-09 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 61 8e-09 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 61 8e-09 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 61 8e-09 gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ... 61 1e-08 gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ... 61 1e-08 gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ... 61 1e-08 gi|4885377 histone cluster 1, H1d [Homo sapiens] 60 1e-08 gi|148612870 chromodomain helicase DNA binding protein 1-like [H... 60 1e-08 gi|6912622 RAD54 homolog B [Homo sapiens] 59 4e-08 >gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo sapiens] Length = 1687 Score = 3413 bits (8850), Expect = 0.0 Identities = 1687/1687 (100%), Positives = 1687/1687 (100%) Query: 1 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS 60 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS Sbjct: 1 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS 60 Query: 61 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT 120 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT Sbjct: 61 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT 120 Query: 121 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS 180 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS Sbjct: 121 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS 180 Query: 181 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL 240 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL Sbjct: 181 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL 240 Query: 241 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL 300 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL Sbjct: 241 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL 300 Query: 301 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP 360 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP Sbjct: 301 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP 360 Query: 361 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK 420 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK Sbjct: 361 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK 420 Query: 421 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR 480 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR Sbjct: 421 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR 480 Query: 481 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK 540 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK Sbjct: 481 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK 540 Query: 541 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH 600 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH Sbjct: 541 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH 600 Query: 601 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE 660 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE Sbjct: 601 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE 660 Query: 661 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI 720 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI Sbjct: 661 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI 720 Query: 721 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN 780 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN Sbjct: 721 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN 780 Query: 781 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG 840 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG Sbjct: 781 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG 840 Query: 841 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL 900 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL Sbjct: 841 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL 900 Query: 901 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS 960 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS Sbjct: 901 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS 960 Query: 961 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK 1020 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK Sbjct: 961 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK 1020 Query: 1021 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA 1080 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA Sbjct: 1021 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA 1080 Query: 1081 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL 1140 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL Sbjct: 1081 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL 1140 Query: 1141 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKGLQFLLTTQ 1200 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKGLQFLLTTQ Sbjct: 1141 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKGLQFLLTTQ 1200 Query: 1201 MEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESK 1260 MEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESK Sbjct: 1201 MEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESK 1260 Query: 1261 LFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVE 1320 LFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVE Sbjct: 1261 LFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVE 1320 Query: 1321 FVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPV 1380 FVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPV Sbjct: 1321 FVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPV 1380 Query: 1381 LHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICA 1440 LHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICA Sbjct: 1381 LHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICA 1440 Query: 1441 RQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKA 1500 RQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKA Sbjct: 1441 RQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKA 1500 Query: 1501 NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFA 1560 NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFA Sbjct: 1501 NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFA 1560 Query: 1561 QISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIG 1620 QISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIG Sbjct: 1561 QISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIG 1620 Query: 1621 RVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFT 1680 RVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFT Sbjct: 1621 RVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFT 1680 Query: 1681 KETEELE 1687 KETEELE Sbjct: 1681 KETEELE 1687 >gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo sapiens] Length = 1659 Score = 3355 bits (8699), Expect = 0.0 Identities = 1656/1656 (100%), Positives = 1656/1656 (100%) Query: 1 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS 60 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS Sbjct: 1 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS 60 Query: 61 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT 120 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT Sbjct: 61 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT 120 Query: 121 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS 180 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS Sbjct: 121 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS 180 Query: 181 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL 240 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL Sbjct: 181 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL 240 Query: 241 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL 300 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL Sbjct: 241 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL 300 Query: 301 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP 360 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP Sbjct: 301 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP 360 Query: 361 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK 420 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK Sbjct: 361 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK 420 Query: 421 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR 480 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR Sbjct: 421 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR 480 Query: 481 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK 540 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK Sbjct: 481 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK 540 Query: 541 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH 600 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH Sbjct: 541 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH 600 Query: 601 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE 660 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE Sbjct: 601 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE 660 Query: 661 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI 720 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI Sbjct: 661 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI 720 Query: 721 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN 780 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN Sbjct: 721 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN 780 Query: 781 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG 840 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG Sbjct: 781 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG 840 Query: 841 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL 900 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL Sbjct: 841 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL 900 Query: 901 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS 960 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS Sbjct: 901 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS 960 Query: 961 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK 1020 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK Sbjct: 961 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK 1020 Query: 1021 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA 1080 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA Sbjct: 1021 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA 1080 Query: 1081 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL 1140 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL Sbjct: 1081 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL 1140 Query: 1141 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKGLQFLLTTQ 1200 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKGLQFLLTTQ Sbjct: 1141 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKGLQFLLTTQ 1200 Query: 1201 MEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESK 1260 MEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESK Sbjct: 1201 MEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESK 1260 Query: 1261 LFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVE 1320 LFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVE Sbjct: 1261 LFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVE 1320 Query: 1321 FVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPV 1380 FVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPV Sbjct: 1321 FVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPV 1380 Query: 1381 LHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICA 1440 LHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICA Sbjct: 1381 LHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICA 1440 Query: 1441 RQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKA 1500 RQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKA Sbjct: 1441 RQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKA 1500 Query: 1501 NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFA 1560 NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFA Sbjct: 1501 NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFA 1560 Query: 1561 QISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIG 1620 QISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIG Sbjct: 1561 QISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIG 1620 Query: 1621 RVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERS 1656 RVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERS Sbjct: 1621 RVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERS 1656 >gi|40807471 transcription termination factor, RNA polymerase II [Homo sapiens] Length = 1162 Score = 113 bits (283), Expect = 1e-24 Identities = 95/337 (28%), Positives = 148/337 (43%), Gaps = 44/337 (13%) Query: 714 STRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYD 773 ++ TLII P+S+ H W +E+ + V S+ LRV +Y G +D + L+ DIVI TY Sbjct: 640 TSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDS--RARVLSTYDIVITTYS 697 Query: 774 VLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAE 833 ++ E+ +N ++ +PL+ + W RI LDEA V+ P V+ + Sbjct: 698 LVAKEIP------TNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSI 751 Query: 834 MAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLY 893 +L RW ++GTP+Q L D++ L+ FL P+ + W R KK + L Sbjct: 752 AVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLW-RSQVDNGSKKGGERL- 809 Query: 894 SFIAKILWRSAKKDVIDQ-----IQIPPQTEEIHWLHFSPVERHFYH------------- 935 S + K L KD +D + +P + ++H L S E Y+ Sbjct: 810 SILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSY 869 Query: 936 -RQHEV-CCQDVVVKLRKISDWALKLSSLD----------RRTVTSILYPLLRLRQACCH 983 ++HE Q S AL+ S + R + IL LLRLRQ CCH Sbjct: 870 LKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCH 929 Query: 984 PQAVRGEFLPLQKSFEQSTFS----FSTMTMEELLTS 1016 ++ P++ E S S +T+ EL S Sbjct: 930 LSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDS 966 Score = 83.2 bits (204), Expect = 2e-15 Identities = 49/171 (28%), Positives = 88/171 (51%), Gaps = 4/171 (2%) Query: 1513 STKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQIS---RVKTFQ 1569 STK+ +++ L IQ K+++ S W ++L +++ L + + +A I K Sbjct: 990 STKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRM 1049 Query: 1570 ENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTK 1629 + + AF ++L+ L G GL + H+ L++ NP+ E QA R++R+GQ K Sbjct: 1050 DLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQK 1109 Query: 1630 PTIVHRFLIKATIEER-MQAMLKTAERSHTNSSAKHSEASVLTVADLADLF 1679 ++HRF+ + T+EE+ +Q K + + S + LT+ADL LF Sbjct: 1110 DVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLF 1160 Score = 43.5 bits (101), Expect = 0.002 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 27/104 (25%) Query: 319 ECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGC----IIREYPNS--GPQLL----- 367 +C+R + +H +W+ +TSE + + C ++ E P P LL Sbjct: 521 QCYRGH-TNQDHVHAVWK--ITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQA 577 Query: 368 -------------GGILADEMGLGKTVEVLALILTHTRQDVKQD 398 GGILAD+MGLGKT+ ++ALILT Q+ K++ Sbjct: 578 LAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEE 621 >gi|21071052 helicase-like transcription factor [Homo sapiens] Length = 1009 Score = 111 bits (277), Expect = 7e-24 Identities = 81/275 (29%), Positives = 122/275 (44%), Gaps = 39/275 (14%) Query: 716 RATLIISPSSICHQWVDEINRHVRSS-SLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDV 774 R TLII P S+ W+D+ +H++S L VY G D +P L++QDIV+ TY++ Sbjct: 476 RTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYG--PDRIREPALLSKQDIVLTTYNI 533 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 L H G SPL ++ W R+ LDE + P + + Sbjct: 534 LT---------HDYGTKG------------DSPLHSIRWLRVILDEGHAIRNPNAQQTKA 572 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNP---QH 891 L RW ++GTP+Q L+DL+ L+ FL ++P+ + WW R + RP + + Sbjct: 573 VLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHRTIQRPVTMGDEGGLRR 632 Query: 892 LYSFIAKILWRSAKKDVI---DQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVK 948 L S I I R K I +++P + I + S ER Y V + Sbjct: 633 LQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSDEERKIY---QSVKNEGRATI 689 Query: 949 LRKISDWALKLSSLDRRTVTSILYPLLRLRQACCH 983 R ++ + D +L LLRLRQ CCH Sbjct: 690 GRYFNEGTVLAHYAD------VLGLLLRLRQICCH 718 Score = 94.4 bits (233), Expect = 9e-19 Identities = 65/221 (29%), Positives = 105/221 (47%), Gaps = 16/221 (7%) Query: 1434 EPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISY 1493 E C IC L + C H FC CI +I+ + + KC +CR + Sbjct: 758 EECAICLDSLTVP-VITHCAHVFCKPCICQVIQ-----NEQPHAKCPLCRNDIHEDNLLE 811 Query: 1494 VFTSEKA-NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKAL 1552 E A + E+ ++ + S+K+ A++ L ++ ++P K+LV S + L +I L Sbjct: 812 CPPEELARDSEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPL 871 Query: 1553 TDNNMEF-------AQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLL 1605 + F AQ RV++ Q + P I+LL L G GL + A+ V L Sbjct: 872 KASGFVFTRLDGSMAQKKRVESIQCFQNTEAGSP--TIMLLSLKAGGVGLNLSAASRVFL 929 Query: 1606 VEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERM 1646 ++P NPA E Q R HR+GQ + I+ +F++K ++EE M Sbjct: 930 MDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENM 970 Score = 52.8 bits (125), Expect = 3e-06 Identities = 43/148 (29%), Positives = 69/148 (46%), Gaps = 31/148 (20%) Query: 272 DIDELYHFVKQ---THQQETQSIQVDVQHPALIPVLRPYQREAVNWMLQQECFRSSPATE 328 + D+L+ +K+ TH+ E A+ L P+Q++A+ WM+ +E + P Sbjct: 213 EFDKLFEDLKEDDKTHEMEPAE--------AIETPLLPHQKQALAWMVSRENSKELPP-- 262 Query: 329 SALHFLWREIVTSEGLKLYYNPYTGCIIREYPNSGPQLLGGILADEMGLGKTVEVLALIL 388 W + LYYN T ++ P + + GGILAD+MGLGKT+ +A+IL Sbjct: 263 -----FWEQ-----RNDLYYNTITNFSEKDRPEN---VHGGILADDMGLGKTLTAIAVIL 309 Query: 389 THTRQDVKQDALTLPEGKVVNYFIPSHY 416 T+ D LP +V + Y Sbjct: 310 TNF-----HDGRPLPIERVKKNLLKKEY 332 >gi|21071054 helicase-like transcription factor [Homo sapiens] Length = 1009 Score = 111 bits (277), Expect = 7e-24 Identities = 81/275 (29%), Positives = 122/275 (44%), Gaps = 39/275 (14%) Query: 716 RATLIISPSSICHQWVDEINRHVRSS-SLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDV 774 R TLII P S+ W+D+ +H++S L VY G D +P L++QDIV+ TY++ Sbjct: 476 RTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYG--PDRIREPALLSKQDIVLTTYNI 533 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 L H G SPL ++ W R+ LDE + P + + Sbjct: 534 LT---------HDYGTKG------------DSPLHSIRWLRVILDEGHAIRNPNAQQTKA 572 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNP---QH 891 L RW ++GTP+Q L+DL+ L+ FL ++P+ + WW R + RP + + Sbjct: 573 VLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHRTIQRPVTMGDEGGLRR 632 Query: 892 LYSFIAKILWRSAKKDVI---DQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVK 948 L S I I R K I +++P + I + S ER Y V + Sbjct: 633 LQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSDEERKIY---QSVKNEGRATI 689 Query: 949 LRKISDWALKLSSLDRRTVTSILYPLLRLRQACCH 983 R ++ + D +L LLRLRQ CCH Sbjct: 690 GRYFNEGTVLAHYAD------VLGLLLRLRQICCH 718 Score = 94.4 bits (233), Expect = 9e-19 Identities = 65/221 (29%), Positives = 105/221 (47%), Gaps = 16/221 (7%) Query: 1434 EPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISY 1493 E C IC L + C H FC CI +I+ + + KC +CR + Sbjct: 758 EECAICLDSLTVP-VITHCAHVFCKPCICQVIQ-----NEQPHAKCPLCRNDIHEDNLLE 811 Query: 1494 VFTSEKA-NQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKAL 1552 E A + E+ ++ + S+K+ A++ L ++ ++P K+LV S + L +I L Sbjct: 812 CPPEELARDSEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPL 871 Query: 1553 TDNNMEF-------AQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLL 1605 + F AQ RV++ Q + P I+LL L G GL + A+ V L Sbjct: 872 KASGFVFTRLDGSMAQKKRVESIQCFQNTEAGSP--TIMLLSLKAGGVGLNLSAASRVFL 929 Query: 1606 VEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERM 1646 ++P NPA E Q R HR+GQ + I+ +F++K ++EE M Sbjct: 930 MDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENM 970 Score = 52.8 bits (125), Expect = 3e-06 Identities = 43/148 (29%), Positives = 69/148 (46%), Gaps = 31/148 (20%) Query: 272 DIDELYHFVKQ---THQQETQSIQVDVQHPALIPVLRPYQREAVNWMLQQECFRSSPATE 328 + D+L+ +K+ TH+ E A+ L P+Q++A+ WM+ +E + P Sbjct: 213 EFDKLFEDLKEDDKTHEMEPAE--------AIETPLLPHQKQALAWMVSRENSKELPP-- 262 Query: 329 SALHFLWREIVTSEGLKLYYNPYTGCIIREYPNSGPQLLGGILADEMGLGKTVEVLALIL 388 W + LYYN T ++ P + + GGILAD+MGLGKT+ +A+IL Sbjct: 263 -----FWEQ-----RNDLYYNTITNFSEKDRPEN---VHGGILADDMGLGKTLTAIAVIL 309 Query: 389 THTRQDVKQDALTLPEGKVVNYFIPSHY 416 T+ D LP +V + Y Sbjct: 310 TNF-----HDGRPLPIERVKKNLLKKEY 332 >gi|58331268 excision repair protein ERCC6-like [Homo sapiens] Length = 1250 Score = 80.5 bits (197), Expect = 1e-14 Identities = 51/163 (31%), Positives = 87/163 (53%), Gaps = 9/163 (5%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTF----QENLSAFKRDPQIN 1582 +LRD G + LVFS + +L+II + L + + + +I T ++ ++ F+++ + Sbjct: 471 RLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYS 530 Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 + LL G GLT+ AT V++ +P NPA + QA+ RV+RIGQ + +V+R + T+ Sbjct: 531 VFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTV 590 Query: 1643 EE---RMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKE 1682 EE R Q + R T K + + +L +LFT E Sbjct: 591 EEKIYRRQVFKDSLIRQTTGE--KKNPFRYFSKQELRELFTIE 631 Score = 45.8 bits (107), Expect = 3e-04 Identities = 37/148 (25%), Positives = 67/148 (45%), Gaps = 25/148 (16%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQ--DIVIITYDVLR 776 L+I P+++ + WV E + + +RV + G KD + +Q ++I TY +L Sbjct: 149 LLIMPTNLINTWVKEFIKW--TPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLI 206 Query: 777 SELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQ 836 + N + R Q+ W + LDEA ++ + K+A A+ Sbjct: 207 N----------NWQQLSSFRGQE-----------FVWDYVILDEAHKIKTSSTKSAICAR 245 Query: 837 RLSGINRWCISGTPVQRGLEDLFGLVVF 864 + NR ++GTP+Q L++L+ L F Sbjct: 246 AIPASNRLLLTGTPIQNNLQELWSLFDF 273 Score = 35.4 bits (80), Expect = 0.47 Identities = 14/20 (70%), Positives = 19/20 (95%) Query: 368 GGILADEMGLGKTVEVLALI 387 GGILAD+MGLGKTV+++A + Sbjct: 117 GGILADDMGLGKTVQIIAFL 136 >gi|21914927 helicase, lymphoid-specific [Homo sapiens] Length = 838 Score = 74.3 bits (181), Expect = 9e-13 Identities = 39/123 (31%), Positives = 68/123 (55%), Gaps = 3/123 (2%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQE---NLSAFKRDPQINI 1583 +L+ G K L+FS +LDI+ + F+++ ++ E N+ +F DP++ I Sbjct: 610 ELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFI 669 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 L+ G G+ + A V++ + NP +LQA R HRIGQTKP +V+R + TI+ Sbjct: 670 FLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTID 729 Query: 1644 ERM 1646 +++ Sbjct: 730 QKI 732 Score = 36.6 bits (83), Expect = 0.21 Identities = 21/45 (46%), Positives = 27/45 (60%), Gaps = 8/45 (17%) Query: 351 YTGCIIREYPNSGPQLL--------GGILADEMGLGKTVEVLALI 387 +TG ++R Y G + L GILADEMGLGKTV+ +A I Sbjct: 218 FTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATI 262 Score = 36.2 bits (82), Expect = 0.28 Identities = 29/135 (21%), Positives = 59/135 (43%), Gaps = 15/135 (11%) Query: 813 WWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPY-- 870 W + +DE ++ + +R + N+ ++GTP+Q L +L+ L+ FL + + Sbjct: 348 WKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDD 407 Query: 871 --CVKHWW--------VRLLYRPYCKKNPQH-LYSFIAKILWRSAKKDVIDQIQIPPQTE 919 + W+ + ++N H L+ + L R K DV +++PP+ E Sbjct: 408 LKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDV--ALEVPPKRE 465 Query: 920 EIHWLHFSPVERHFY 934 + + S + FY Sbjct: 466 VVVYAPLSKKQEIFY 480 >gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa [Homo sapiens] Length = 1849 Score = 74.3 bits (181), Expect = 9e-13 Identities = 48/158 (30%), Positives = 78/158 (49%), Gaps = 7/158 (4%) Query: 1534 KALVFSTWQDVLDIISKALTDNNMEFAQISRVKTF------QENLSAFKRDPQINILLLP 1587 + L+F + +LDI+ L ++ R+ +S F DP I++LLL Sbjct: 1646 RILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLT 1705 Query: 1588 LHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQ 1647 H G GL + A V+ VE NP +LQA+ R HRIGQ + V+R + + T+EE++ Sbjct: 1706 THVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIM 1765 Query: 1648 AMLK-TAERSHTNSSAKHSEASVLTVADLADLFTKETE 1684 + K ++T S ++S + L DLFT + + Sbjct: 1766 GLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKD 1803 Score = 60.8 bits (146), Expect = 1e-08 Identities = 59/288 (20%), Positives = 115/288 (39%), Gaps = 49/288 (17%) Query: 718 TLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRS 777 +L++ P ++ WVDE+ + L L Y G + H + ++++ +YDV+R+ Sbjct: 1329 SLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRN 1388 Query: 778 ELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQR 837 ++++ RN K I LDE +++ K ++ ++ Sbjct: 1389 DIDF-------------FRNIKFNYCI-------------LDEGHVIKNGKTKLSKAVKQ 1422 Query: 838 LSGINRWCISGTPVQRGLEDLFGLV-----VFLGIEPYCVKHWWVRLLYRPYCKKNPQH- 891 L+ R +SGTP+Q + +L+ L FLG E + +L + + + Sbjct: 1423 LTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQ 1482 Query: 892 ---------LYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYH---RQHE 939 L+ + L R K+DV+ +PP+ + ++ SP++ Y + Sbjct: 1483 EAGVLAMDALHRQVLPFLLRRMKEDVLQ--DLPPKIIQDYYCTLSPLQVQLYEDFAKSRA 1540 Query: 940 VCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAV 987 C D V +S+ + + + L LR+ C HP V Sbjct: 1541 KCDVDETVSSATLSE---ETEKPKLKATGHVFQALQYLRKLCNHPALV 1585 Score = 31.2 bits (69), Expect = 8.9 Identities = 47/186 (25%), Positives = 72/186 (38%), Gaps = 40/186 (21%) Query: 332 HFLWREIVTSEGLKLYYNPYT-GCIIREYPNSGPQLLG--------GILADEMGLGKTVE 382 HFL +++ + L+ Y P +R+Y G L GIL D+MGLGKT++ Sbjct: 1242 HFL-EQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQ 1300 Query: 383 VLALIL---THTRQDVKQ----DALTLPEGKVVNYFIPSHYFG--GKLKKTEIQNIEFEP 433 + ++ H Q+ + + + LP V + H+ GK E N P Sbjct: 1301 SICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSREYLN----P 1356 Query: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLK---CL 490 P R+ + VK N + YDV RN R +K C+ Sbjct: 1357 LHYTGPPTERIRLQHQVKRHN--------------LIVASYDVVRNDIDFFRNIKFNYCI 1402 Query: 491 IFEGLV 496 + EG V Sbjct: 1403 LDEGHV 1408 >gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sapiens] Length = 1954 Score = 69.3 bits (168), Expect = 3e-11 Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 8/185 (4%) Query: 1510 GSHSTKVEAVVRTLMKI--QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKT 1567 GS K + L K+ +LRD G + L+FS +LD++ L ++ +I T Sbjct: 1016 GSSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGIT 1075 Query: 1568 F---QENLSAFKRD-PQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVH 1623 QE + F Q LL G G+ + A V++ + NP +++QA R H Sbjct: 1076 GGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAH 1135 Query: 1624 RIGQTKPTIVHRFLIKATIEERM-QAMLKTAERSH-TNSSAKHSEASVLTVADLADLFTK 1681 RIGQ K +++RF+ +A++EER+ Q + +H S++ +T +L D+ Sbjct: 1136 RIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDILKF 1195 Query: 1682 ETEEL 1686 TEEL Sbjct: 1196 GTEEL 1200 Score = 41.6 bits (96), Expect = 0.007 Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 32/234 (13%) Query: 808 LVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGI 867 L ++EW + +DEA ++ K + + ++GTP+Q LE+LF L+ FL Sbjct: 836 LGSIEWACLVVDEAHRLKNNQSKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTP 895 Query: 868 EPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFS 927 E + ++ + + L+ + + R K DV +P +TE I + S Sbjct: 896 ERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFK--NMPAKTELIVRVELS 953 Query: 928 PVERHFYHRQHEVCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHP--- 984 +++ +Y + R L+S S+L ++ L++ C HP Sbjct: 954 QMQKKYYK----------FILTRNFE----ALNSKGGGNQVSLLNIMMDLKKCCNHPYLF 999 Query: 985 --QAVRGEFLPLQKSFEQSTF---SFSTMTMEELLTSLQKKCGTECEEAHRQLV 1033 AV LP S++ S+ S M ++++L L+ +E HR L+ Sbjct: 1000 PVAAVEAPVLP-NGSYDGSSLVKSSGKLMLLQKMLKKLR-------DEGHRVLI 1045 >gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo sapiens] Length = 1079 Score = 69.3 bits (168), Expect = 3e-11 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 3/134 (2%) Query: 1520 VRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENL---SAFK 1576 V+ +K+ L++ K LVF+ +L ++A+ +N + +I + E + + F+ Sbjct: 326 VKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVSSSERIHLVNQFQ 385 Query: 1577 RDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRF 1636 +DP + +L + GLT A+HV+ E +P H QA R HRIGQ +H Sbjct: 386 KDPDTRVAILSIQAAGQGLTFTAASHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYL 445 Query: 1637 LIKATIEERMQAML 1650 + T++ M ML Sbjct: 446 IANGTLDTLMWGML 459 >gi|58219008 RAD26L hypothetical protein [Homo sapiens] Length = 712 Score = 67.4 bits (163), Expect = 1e-10 Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 28/276 (10%) Query: 1396 LLNDKAVATSQLQKKLGQLLY--LTNLEKS--------QDKTSGGVNPEPCPICARQLGK 1445 L K + QL KK +++Y LT+ +K+ +D T + EPC + Q + Sbjct: 380 LRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRR 439 Query: 1446 QWAVLTCGHCFCNECISIIIEQY-----SVGSHRSSIKCAIC--RQTTSHKEI-SYVFTS 1497 T H E + + Y V +H + ++ A +Q T K I VF+ Sbjct: 440 NCCYKTNSH---GETVKTLYLSYLTVLQKVANHVALLQAASTSKQQETLIKRICDQVFSR 496 Query: 1498 --EKANQEEDIPVKGSHSTKVEAVVRTLMKI--QLRDPGAKALVFSTWQDVLDIISKALT 1553 + + +D + K ++ L ++ R K L+FS +LD++ + Sbjct: 497 FPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNRDKVLLFSFSTKLLDVLQQYCM 556 Query: 1554 DNNMEFAQISRVKTFQENLSA---FKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPIL 1610 + +++ ++ +E L F +NI L+ G GL + A V+L +P Sbjct: 557 ASGLDYRRLDGSTKSEERLKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTW 616 Query: 1611 NPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERM 1646 NPA++LQAI R +RIGQ + V R + T+EE M Sbjct: 617 NPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIM 652 Score = 45.8 bits (107), Expect = 3e-04 Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 43/170 (25%) Query: 711 EPVSTRAT---LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDI 767 EP+S+ A LI++P S+ + W DE++ RV V G +KD L + +I Sbjct: 201 EPLSSTAKKMFLIVAPLSVLYNWKDELDTW---GYFRVTVLHGNRKDNELIRVKQRKCEI 257 Query: 768 VIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECP 827 + TY+ LR L+ L ++EW + +DEA ++ P Sbjct: 258 ALTTYETLRLCLD--------------------------ELNSLEWSAVIVDEAHRIKNP 291 Query: 828 TVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWV 877 + E+ + L R ++GT +Q +++L +CV W V Sbjct: 292 KARVTEVMKALKCNVRIGLTGTILQNNMKEL-----------WCVMDWAV 330 Score = 34.7 bits (78), Expect = 0.81 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 14/63 (22%) Query: 350 PYT-GCIIREYPNSGPQLLGG--------ILADEMGLGKTVEVLALILT-----HTRQDV 395 PYT +R+Y G + L G IL D+MGLGKTV+V++ + TR+D+ Sbjct: 127 PYTINRYLRDYQREGTRFLYGHYIHGGGCILGDDMGLGKTVQVISFLAAVLHKKGTREDI 186 Query: 396 KQD 398 + + Sbjct: 187 ENN 189 >gi|21071058 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a5 [Homo sapiens] Length = 1052 Score = 65.9 bits (159), Expect = 3e-10 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 4/124 (3%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKRDPQIN---- 1582 +L++ G++ L+FS VLDI+ N E+ ++ E + + N Sbjct: 494 KLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKF 553 Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 + +L G G+ + A V+L + NP +LQA+ R HRIGQTK V RF+ T+ Sbjct: 554 VFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTV 613 Query: 1643 EERM 1646 EER+ Sbjct: 614 EERI 617 Score = 60.5 bits (145), Expect = 1e-08 Identities = 65/308 (21%), Positives = 125/308 (40%), Gaps = 48/308 (15%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFL-AEQDIVIITYDVLRS 777 +++ P S H W+ E R V + L+ ++ F++ L E D+ + +Y++L Sbjct: 233 MVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIK 292 Query: 778 ELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQR 837 E S W + +DEA ++ K +E+ + Sbjct: 293 E--------------------------KSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVRE 326 Query: 838 LSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYC---KKNPQHLYS 894 NR ++GTP+Q L +L+ L+ FL + + + C +K + L+ Sbjct: 327 FKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHM 386 Query: 895 FIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISD 954 + L R K DV + +PP+ E ++ S ++R +Y R + +D+ + Sbjct: 387 VLRPFLLRRIKADV--EKSLPPKKEVKIYVGLSKMQREWYTR---ILMKDIDI------- 434 Query: 955 WALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRG--EFLPLQKSFEQSTFSFSTMTMEE 1012 L+S + +L L++LR+ C HP G P T S + +++ Sbjct: 435 ----LNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDK 490 Query: 1013 LLTSLQKK 1020 LL L+++ Sbjct: 491 LLPKLKEQ 498 Score = 34.3 bits (77), Expect = 1.1 Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 2/46 (4%) Query: 367 LGGILADEMGLGKTVEVLALI--LTHTRQDVKQDALTLPEGKVVNY 410 + GILADEMGLGKT++ ++L+ + H R + +P+ + N+ Sbjct: 199 INGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNW 244 >gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sapiens] Length = 1912 Score = 64.7 bits (156), Expect = 7e-10 Identities = 46/165 (27%), Positives = 78/165 (47%), Gaps = 6/165 (3%) Query: 1528 LRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKR----DPQINI 1583 L++ G + L+FS +LD++ L ++ +I T A R Q Sbjct: 1062 LKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFC 1121 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 LL G G+ + A V++ + NP +++QA R HRIGQ K +++RF+ +A++E Sbjct: 1122 FLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVE 1181 Query: 1644 ERM-QAMLKTAERSH-TNSSAKHSEASVLTVADLADLFTKETEEL 1686 ER+ Q K +H S+ ++ +L D+ TEEL Sbjct: 1182 ERITQVAKKKMMLTHLVVRPGLGSKTGSMSKQELDDILKFGTEEL 1226 Score = 41.6 bits (96), Expect = 0.007 Identities = 31/127 (24%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Query: 808 LVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGI 867 L +++W + +DEA ++ K + S ++ ++GTP+Q LE+LF L+ FL Sbjct: 862 LGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTP 921 Query: 868 EPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFS 927 E + ++ + + L+ + + R K DV +P +TE I + S Sbjct: 922 ERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKADVFK--NMPSKTELIVRVELS 979 Query: 928 PVERHFY 934 P+++ +Y Sbjct: 980 PMQKKYY 986 >gi|164419749 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a1 isoform b [Homo sapiens] Length = 1042 Score = 64.7 bits (156), Expect = 7e-10 Identities = 63/277 (22%), Positives = 119/277 (42%), Gaps = 50/277 (18%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVK--KDGFLQPHFL-AEQDIVIITYDVL 775 +++ P S H W++E R V SLRV+ + G K + F++ + E D+ + +Y+++ Sbjct: 236 MVLVPKSTLHNWMNEFKRWV--PSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMV 293 Query: 776 RSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMA 835 E + H W + +DEA ++ K +E+ Sbjct: 294 IKEKSVFKKFH--------------------------WRYLVIDEAHRIKNEKSKLSEIV 327 Query: 836 QRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYC---KKNPQHL 892 + NR ++GTP+Q L +L+ L+ FL + + + C +K + L Sbjct: 328 REFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERL 387 Query: 893 YSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKI 952 ++ + L R K DV + +PP+ E +L S ++R +Y + + +D+ V Sbjct: 388 HAVLKPFLLRRIKTDV--EKSLPPKKEIKIYLGLSKMQREWYTK---ILMKDIDV----- 437 Query: 953 SDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRG 989 L+S + +L L++LR+ C HP G Sbjct: 438 ------LNSSGKMDKMRLLNILMQLRKCCNHPYLFDG 468 Score = 63.9 bits (154), Expect = 1e-09 Identities = 43/140 (30%), Positives = 69/140 (49%), Gaps = 6/140 (4%) Query: 1511 SHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQE 1570 S+S K+ + + L K L++ G++ L+FS +LDI+ E+ ++ +E Sbjct: 483 SNSGKMVVLDKLLAK--LKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE 540 Query: 1571 NLSAFKRDPQIN----ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIG 1626 A + N I +L G G+ + A V+L + NP +LQA+ R HRIG Sbjct: 541 REEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIG 600 Query: 1627 QTKPTIVHRFLIKATIEERM 1646 Q KP V R + T+EER+ Sbjct: 601 QKKPVRVFRLITDNTVEERI 620 Score = 35.8 bits (81), Expect = 0.36 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%) Query: 367 LGGILADEMGLGKTVEVLALI--LTHTRQDVKQDALTLPEGKVVNY 410 + GILADEMGLGKT++ +AL+ L H R + +P+ + N+ Sbjct: 202 VNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNW 247 >gi|21071044 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a1 isoform a [Homo sapiens] Length = 1054 Score = 64.7 bits (156), Expect = 7e-10 Identities = 63/277 (22%), Positives = 119/277 (42%), Gaps = 50/277 (18%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVK--KDGFLQPHFL-AEQDIVIITYDVL 775 +++ P S H W++E R V SLRV+ + G K + F++ + E D+ + +Y+++ Sbjct: 236 MVLVPKSTLHNWMNEFKRWV--PSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMV 293 Query: 776 RSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMA 835 E + H W + +DEA ++ K +E+ Sbjct: 294 IKEKSVFKKFH--------------------------WRYLVIDEAHRIKNEKSKLSEIV 327 Query: 836 QRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYC---KKNPQHL 892 + NR ++GTP+Q L +L+ L+ FL + + + C +K + L Sbjct: 328 REFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERL 387 Query: 893 YSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKI 952 ++ + L R K DV + +PP+ E +L S ++R +Y + + +D+ V Sbjct: 388 HAVLKPFLLRRIKTDV--EKSLPPKKEIKIYLGLSKMQREWYTK---ILMKDIDV----- 437 Query: 953 SDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRG 989 L+S + +L L++LR+ C HP G Sbjct: 438 ------LNSSGKMDKMRLLNILMQLRKCCNHPYLFDG 468 Score = 58.2 bits (139), Expect = 7e-08 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 18/152 (11%) Query: 1511 SHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQE 1570 S+S K+ + + L K L++ G++ L+FS +LDI+ E+ ++ +E Sbjct: 483 SNSGKMVVLDKLLAK--LKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE 540 Query: 1571 NLSAFKRDPQIN----------------ILLLPLHTGSNGLTIIEATHVLLVEPILNPAH 1614 F + I +L G G+ + A V+L + NP Sbjct: 541 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV 600 Query: 1615 ELQAIGRVHRIGQTKPTIVHRFLIKATIEERM 1646 +LQA+ R HRIGQ KP V R + T+EER+ Sbjct: 601 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERI 632 Score = 35.8 bits (81), Expect = 0.36 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%) Query: 367 LGGILADEMGLGKTVEVLALI--LTHTRQDVKQDALTLPEGKVVNY 410 + GILADEMGLGKT++ +AL+ L H R + +P+ + N+ Sbjct: 202 VNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNW 247 >gi|38708321 INO80 complex homolog 1 [Homo sapiens] Length = 1556 Score = 63.9 bits (154), Expect = 1e-09 Identities = 42/165 (25%), Positives = 81/165 (49%), Gaps = 5/165 (3%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQI---SRVKTFQENLSAFKRDPQINI 1583 +L+ G + L++S ++D++ + + + ++ S++ ++ ++ F+ I + Sbjct: 1112 RLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADFQNRNDIFV 1171 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 LL G G+ + A V+ + NP + QA+ R HR+GQTK V+R + K TIE Sbjct: 1172 FLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIE 1231 Query: 1644 ER-MQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETEELE 1687 ER +Q + +E S + + L ++ L + EELE Sbjct: 1232 ERILQRAKEKSEIQRMVISGGNFKPDTLKPKEVVSLLL-DDEELE 1275 Score = 43.5 bits (101), Expect = 0.002 Identities = 56/287 (19%), Positives = 117/287 (40%), Gaps = 57/287 (19%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKD-----GFLQPHFLAEQD----IVI 769 LIISP+S + W E R V +VL Y G D F L QD +VI Sbjct: 571 LIISPASTLNNWHQEFTRFV--PKFKVLPYWGNPHDRKVIRRFWSQKTLYTQDAPFHVVI 628 Query: 770 ITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTV 829 +Y ++ ++ Y V+W + LDEAQ ++ + Sbjct: 629 TSYQLVVQDVKYFQ--------------------------RVKWQYMVLDEAQALKSSSS 662 Query: 830 KAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYC----VKHWWVRLLYRPYC 885 ++ + NR ++GTP+Q + +L+ L+ F+ + W+ + + Sbjct: 663 VRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAE 722 Query: 886 KKNP------QHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHR-QH 938 K+ L+ + + R KKDV + ++ + E + + + ++ Y ++ Sbjct: 723 NKSAIDENQLSRLHMILKPFMLRRIKKDV--ENELSDKIEILMYCQLTSRQKLLYQALKN 780 Query: 939 EVCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQ 985 ++ +D++ ++ + + T +S++ +++ R+ C HP+ Sbjct: 781 KISIEDLLQS-------SMGSTQQAQNTTSSLMNLVMQFRKVCNHPE 820 Score = 35.0 bits (79), Expect = 0.62 Identities = 16/23 (69%), Positives = 20/23 (86%) Query: 365 QLLGGILADEMGLGKTVEVLALI 387 Q + GILADEMGLGKTV+ +AL+ Sbjct: 535 QGINGILADEMGLGKTVQSIALL 557 >gi|4557565 excision repair cross-complementing rodent repair deficiency, complementation group 6 [Homo sapiens] Length = 1493 Score = 63.5 bits (153), Expect = 2e-09 Identities = 41/131 (31%), Positives = 66/131 (50%), Gaps = 4/131 (3%) Query: 1519 VVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTF---QENLSAF 1575 VV +L+KI + G + L+FS + +LDI+ L + ++ T Q ++ + Sbjct: 843 VVESLLKIWHKQ-GQRVLLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRY 901 Query: 1576 KRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHR 1635 D I + LL G G+ + A V++ +P NP+ + QA R RIGQ K V+R Sbjct: 902 NEDTSIFVFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYR 961 Query: 1636 FLIKATIEERM 1646 L TIEE++ Sbjct: 962 LLTAGTIEEKI 972 Score = 43.9 bits (102), Expect = 0.001 Identities = 59/290 (20%), Positives = 111/290 (38%), Gaps = 62/290 (21%) Query: 718 TLIISPSSICHQWVDEINRHVRSSSLRVLVYQGV---KKDGFLQPHFLAEQDIVIITYDV 774 T+I+ P+++ HQWV E + + +L G KK+ ++ V + + Sbjct: 569 TVIVCPTTVMHQWVKEFHTWWPPFRVAILHETGSYTHKKEKLIRD--------VAHCHGI 620 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 L + +Y+ + + RY +W + LDE + P Sbjct: 621 LITSYSYIRLMQDDIS---------RY----------DWHYVILDEGHKIRNPNAAVTLA 661 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVF-----LGIEPYCVKHWWVRLLYRPYCKKNP 889 ++ +R +SG+P+Q L +L+ L F LG P ++ + V + Y +P Sbjct: 662 CKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASP 721 Query: 890 QH----------LYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHE 939 L I L R K DV + +P + E++ + + + Y Q+ Sbjct: 722 VQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVY--QNF 779 Query: 940 VCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRG 989 V ++V +I + +++ S L+ LR+ C HP G Sbjct: 780 VDSKEVY----RILNGEMQIFS-----------GLIALRKICNHPDLFSG 814 Score = 35.4 bits (80), Expect = 0.47 Identities = 14/23 (60%), Positives = 19/23 (82%) Query: 365 QLLGGILADEMGLGKTVEVLALI 387 Q GGIL DEMGLGKT++++A + Sbjct: 524 QQAGGILGDEMGLGKTIQIIAFL 546 >gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1 [Homo sapiens] Length = 2000 Score = 62.8 bits (151), Expect = 3e-09 Identities = 46/166 (27%), Positives = 81/166 (48%), Gaps = 6/166 (3%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTF---QENLSAFKRD-PQIN 1582 +L++ G + L+FS +LD++ L ++ +I T QE + F Q Sbjct: 1071 KLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQF 1130 Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 LL G G+ + A V++ + NP +++QA R HRIGQ +++RF+ +A++ Sbjct: 1131 CFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASV 1190 Query: 1643 EERM-QAMLKTAERSH-TNSSAKHSEASVLTVADLADLFTKETEEL 1686 EER+ Q + +H S+A ++ +L D+ TEEL Sbjct: 1191 EERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEEL 1236 Score = 40.0 bits (92), Expect = 0.019 Identities = 48/226 (21%), Positives = 90/226 (39%), Gaps = 16/226 (7%) Query: 808 LVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGI 867 L ++ W + +DEA ++ K + ++ ++GTP+Q LE+LF L+ FL Sbjct: 872 LGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTP 931 Query: 868 EPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFS 927 E + ++ + + L+ + + R K DV +P +TE I + S Sbjct: 932 ERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFK--NMPAKTELIVRVELS 989 Query: 928 PVERHFYHRQHEVCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAV 987 P+++ +Y + R L+S S+L ++ L++ C HP Sbjct: 990 PMQKKYYK----------YILTRNFE----ALNSRGGGNQVSLLNIMMDLKKCCNHPYLF 1035 Query: 988 RGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKKCGTECEEAHRQLV 1033 + K + + + L LQK E+ HR L+ Sbjct: 1036 PVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLI 1081 >gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2 [Homo sapiens] Length = 1966 Score = 62.8 bits (151), Expect = 3e-09 Identities = 46/166 (27%), Positives = 81/166 (48%), Gaps = 6/166 (3%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTF---QENLSAFKRD-PQIN 1582 +L++ G + L+FS +LD++ L ++ +I T QE + F Q Sbjct: 1071 KLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQF 1130 Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 LL G G+ + A V++ + NP +++QA R HRIGQ +++RF+ +A++ Sbjct: 1131 CFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASV 1190 Query: 1643 EERM-QAMLKTAERSH-TNSSAKHSEASVLTVADLADLFTKETEEL 1686 EER+ Q + +H S+A ++ +L D+ TEEL Sbjct: 1191 EERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEEL 1236 Score = 40.0 bits (92), Expect = 0.019 Identities = 48/226 (21%), Positives = 90/226 (39%), Gaps = 16/226 (7%) Query: 808 LVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGI 867 L ++ W + +DEA ++ K + ++ ++GTP+Q LE+LF L+ FL Sbjct: 872 LGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTP 931 Query: 868 EPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFS 927 E + ++ + + L+ + + R K DV +P +TE I + S Sbjct: 932 ERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFK--NMPAKTELIVRVELS 989 Query: 928 PVERHFYHRQHEVCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAV 987 P+++ +Y + R L+S S+L ++ L++ C HP Sbjct: 990 PMQKKYYK----------YILTRNFE----ALNSRGGGNQVSLLNIMMDLKKCCNHPYLF 1035 Query: 988 RGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKKCGTECEEAHRQLV 1033 + K + + + L LQK E+ HR L+ Sbjct: 1036 PVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLI 1081 >gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3 [Homo sapiens] Length = 2059 Score = 62.8 bits (151), Expect = 3e-09 Identities = 46/166 (27%), Positives = 81/166 (48%), Gaps = 6/166 (3%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTF---QENLSAFKRD-PQIN 1582 +L++ G + L+FS +LD++ L ++ +I T QE + F Q Sbjct: 1130 KLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQF 1189 Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 LL G G+ + A V++ + NP +++QA R HRIGQ +++RF+ +A++ Sbjct: 1190 CFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASV 1249 Query: 1643 EERM-QAMLKTAERSH-TNSSAKHSEASVLTVADLADLFTKETEEL 1686 EER+ Q + +H S+A ++ +L D+ TEEL Sbjct: 1250 EERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEEL 1295 Score = 40.0 bits (92), Expect = 0.019 Identities = 48/226 (21%), Positives = 90/226 (39%), Gaps = 16/226 (7%) Query: 808 LVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGI 867 L ++ W + +DEA ++ K + ++ ++GTP+Q LE+LF L+ FL Sbjct: 931 LGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTP 990 Query: 868 EPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFS 927 E + ++ + + L+ + + R K DV +P +TE I + S Sbjct: 991 ERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFK--NMPAKTELIVRVELS 1048 Query: 928 PVERHFYHRQHEVCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAV 987 P+++ +Y + R L+S S+L ++ L++ C HP Sbjct: 1049 PMQKKYYK----------YILTRNFE----ALNSRGGGNQVSLLNIMMDLKKCCNHPYLF 1094 Query: 988 RGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKKCGTECEEAHRQLV 1033 + K + + + L LQK E+ HR L+ Sbjct: 1095 PVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLI 1140 >gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1 [Homo sapiens] Length = 1828 Score = 62.4 bits (150), Expect = 4e-09 Identities = 38/124 (30%), Positives = 66/124 (53%), Gaps = 4/124 (3%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQIS---RVKTFQENLSAFKRDPQINI 1583 +LR+ G + L+FS +LDI+++ LT + F ++ + + ++ L F D + Sbjct: 802 RLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDF 861 Query: 1584 -LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 LL G G+ + A V++ + NP ++LQA R HRIGQ K ++R + K T+ Sbjct: 862 CFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTV 921 Query: 1643 EERM 1646 EE + Sbjct: 922 EEEI 925 Score = 36.6 bits (83), Expect = 0.21 Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 7/129 (5%) Query: 808 LVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGI 867 L ++ W + +DEA ++ + +R I+GTP+Q L++L+ L+ F+ Sbjct: 606 LGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMP 665 Query: 868 EPYCVKHWWVRLL--YRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLH 925 E + +W + + Q L+ + L R KKDV + +P + E+I + Sbjct: 666 EKF---EFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDV--EKSLPAKVEQILRVE 720 Query: 926 FSPVERHFY 934 S +++ +Y Sbjct: 721 MSALQKQYY 729 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 61.2 bits (147), Expect = 8e-09 Identities = 30/105 (28%), Positives = 59/105 (56%) Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 + ++ GS G+ ++ A V++ + NP++++Q+I RV+R GQTKP V+RFL + T+ Sbjct: 2074 LFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTM 2133 Query: 1643 EERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETEELE 1687 E+++ T + + T+ +L +L+T E + L+ Sbjct: 2134 EDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLD 2178 Score = 37.0 bits (84), Expect = 0.16 Identities = 60/367 (16%), Positives = 134/367 (36%), Gaps = 49/367 (13%) Query: 516 EEDICDKTKKQAVGSPRKIQKETRKSGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSK 575 +ED + K + + ++E + ++ + E D +DD P + R K Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE----DENDDSKSP-------GKGRKK 1441 Query: 576 LRKKLVPSTKKGKSQPFINPDSQGHCPATSDSG----------ITDVAMSKSTCISEFNQ 625 +RK L + ++Q + + + I D + +K ++ Sbjct: 1442 IRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVL 1501 Query: 626 EHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFECICGELDQIDRKPRVQCLKCHLWQH 685 + E E+ E L ++ + + ++C C + + + P C+ H Sbjct: 1502 D-EDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAH---- 1556 Query: 686 AKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRS----S 741 C+ K L++ F H ++ + + L++ P + W++E + Sbjct: 1557 --CMGLG-KTLQVVSFL--HTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDE 1611 Query: 742 SLRVLVYQGVKKD---GFLQPHFLAEQDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQ 798 L V VK+ ++ + + ++II Y++ R N GR ++++ Sbjct: 1612 KLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYR-----------NLAQGRNVKSR 1660 Query: 799 KRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDL 858 K LV + DE +++ ++ + R ++GTP+Q L + Sbjct: 1661 KLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEY 1720 Query: 859 FGLVVFL 865 +V F+ Sbjct: 1721 HCMVNFI 1727 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 61.2 bits (147), Expect = 8e-09 Identities = 30/105 (28%), Positives = 59/105 (56%) Query: 1583 ILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATI 1642 + ++ GS G+ ++ A V++ + NP++++Q+I RV+R GQTKP V+RFL + T+ Sbjct: 2112 LFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTM 2171 Query: 1643 EERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETEELE 1687 E+++ T + + T+ +L +L+T E + L+ Sbjct: 2172 EDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLD 2216 Score = 37.0 bits (84), Expect = 0.16 Identities = 60/367 (16%), Positives = 134/367 (36%), Gaps = 49/367 (13%) Query: 516 EEDICDKTKKQAVGSPRKIQKETRKSGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSK 575 +ED + K + + ++E + ++ + E D +DD P + R K Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE----DENDDSKSP-------GKGRKK 1479 Query: 576 LRKKLVPSTKKGKSQPFINPDSQGHCPATSDSG----------ITDVAMSKSTCISEFNQ 625 +RK L + ++Q + + + I D + +K ++ Sbjct: 1480 IRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVL 1539 Query: 626 EHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFECICGELDQIDRKPRVQCLKCHLWQH 685 + E E+ E L ++ + + ++C C + + + P C+ H Sbjct: 1540 D-EDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAH---- 1594 Query: 686 AKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRS----S 741 C+ K L++ F H ++ + + L++ P + W++E + Sbjct: 1595 --CMGLG-KTLQVVSFL--HTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDE 1649 Query: 742 SLRVLVYQGVKKD---GFLQPHFLAEQDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQ 798 L V VK+ ++ + + ++II Y++ R N GR ++++ Sbjct: 1650 KLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYR-----------NLAQGRNVKSR 1698 Query: 799 KRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDL 858 K LV + DE +++ ++ + R ++GTP+Q L + Sbjct: 1699 KLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEY 1758 Query: 859 FGLVVFL 865 +V F+ Sbjct: 1759 HCMVNFI 1765 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 61.2 bits (147), Expect = 8e-09 Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 3/123 (2%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQI---SRVKTFQENLSAFKRDPQINI 1583 QL+ G + L+F+ +LD++ + LT + + ++ +RV+ Q + F D +I Sbjct: 2054 QLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFC 2113 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 +L +G G+ + A V+ + NP + QA R HRIGQT+ ++R + + T+E Sbjct: 2114 FILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVE 2173 Query: 1644 ERM 1646 E + Sbjct: 2174 ENI 2176 Score = 38.9 bits (89), Expect = 0.043 Identities = 65/308 (21%), Positives = 118/308 (38%), Gaps = 66/308 (21%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKD------GFLQPHFLAEQDIVIITY 772 LII P+S+ W E+ R S ++L Y G +K+ G+ +P+ + I +Y Sbjct: 671 LIIVPTSVMLNWEMELKRWC--PSFKILTYYGAQKERKLKRQGWTKPNAF---HVCITSY 725 Query: 773 DVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAA 832 ++ +D + R + W + LDEAQ ++ + Sbjct: 726 KLVL-------------QDHQAFRRKN-------------WRYLILDEAQNIKNFKSQRW 759 Query: 833 EMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYC----VKHWWVRLL------YR 882 + + R ++GTP+Q L +L+ L+ FL + K W+ L + Sbjct: 760 QSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHREFKEWFSNPLTGMIEGSQ 819 Query: 883 PYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCC 942 Y + + L+ + L R K DV + Q+P + E + S +R Y Sbjct: 820 EYNEGLVKRLHKVLRPFLLRRVKVDV--EKQMPKKYEHVIRCRLSKRQRCLY-------- 869 Query: 943 QDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQST 1002 D + + +L S++ L++LR+ C HP + P+ F Sbjct: 870 DDFMAQ-------TTTKETLATGHFMSVINILMQLRKVCNHPNLF--DPRPVTSPFITPG 920 Query: 1003 FSFSTMTM 1010 FST ++ Sbjct: 921 ICFSTASL 928 Score = 35.4 bits (80), Expect = 0.47 Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 8/40 (20%) Query: 356 IREYPNSG--------PQLLGGILADEMGLGKTVEVLALI 387 +REY + G + L GILADEMGLGKT++ ++L+ Sbjct: 618 LREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLL 657 >gi|190358536 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 isoform a [Homo sapiens] Length = 1028 Score = 60.8 bits (146), Expect = 1e-08 Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENL---SAFKRDPQINI 1583 +L+ G + ++FS + +LDI+ L + + ++ E + F D I + Sbjct: 867 ELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFV 926 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 LL G G+ + A V+L + NP ++ QA R HR+GQTK +V + + + TIE Sbjct: 927 FLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIE 986 Query: 1644 ERM 1646 E M Sbjct: 987 ESM 989 Score = 43.1 bits (100), Expect = 0.002 Identities = 57/269 (21%), Positives = 107/269 (39%), Gaps = 59/269 (21%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDG----FLQPHFLAEQDIVIITYDV 774 LI+ P+S W+ E+N + +L+VL Y G +++ F + ++++ TY+ Sbjct: 549 LIVVPASTIDNWLREVN--LWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNC 606 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 S +S+D R K AI DE M++ + Sbjct: 607 AIS----------SSDDRSLFRRLKLNYAI-------------FDEGHMLKNMGSIRYQH 643 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRP----------Y 884 ++ NR ++GTPVQ L +L L+ F+ + +R ++ Y Sbjct: 644 LMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIY 703 Query: 885 CKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFY---------- 934 K+ H I + R K++V+ Q+PP+ + I S + Y Sbjct: 704 EKERIAHAKQIIKPFILRRVKEEVLK--QLPPKKDRIELCAMSEKQEQLYLGLFNRLKKS 761 Query: 935 ------HRQHEVCCQDVVVKLRKISDWAL 957 + E+C +V+++LRK+++ L Sbjct: 762 INNLVTEKNTEMC--NVMMQLRKMANHPL 788 Score = 34.3 bits (77), Expect = 1.1 Identities = 14/21 (66%), Positives = 18/21 (85%) Query: 367 LGGILADEMGLGKTVEVLALI 387 L GILADEMGLGKT++ +A + Sbjct: 516 LNGILADEMGLGKTIQAIAFL 536 >gi|190358534 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 isoform b [Homo sapiens] Length = 1026 Score = 60.8 bits (146), Expect = 1e-08 Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENL---SAFKRDPQINI 1583 +L+ G + ++FS + +LDI+ L + + ++ E + F D I + Sbjct: 865 ELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFV 924 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 LL G G+ + A V+L + NP ++ QA R HR+GQTK +V + + + TIE Sbjct: 925 FLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIE 984 Query: 1644 ERM 1646 E M Sbjct: 985 ESM 987 Score = 43.9 bits (102), Expect = 0.001 Identities = 57/267 (21%), Positives = 107/267 (40%), Gaps = 57/267 (21%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDG----FLQPHFLAEQDIVIITYDV 774 LI+ P+S W+ E+N + +L+VL Y G +++ F + ++++ TY+ Sbjct: 549 LIVVPASTIDNWLREVN--LWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNC 606 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 S +S+D R K AI DE M++ + Sbjct: 607 AIS----------SSDDRSLFRRLKLNYAI-------------FDEGHMLKNMGSIRYQH 643 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRP----------Y 884 ++ NR ++GTPVQ L +L L+ F+ + +R ++ Y Sbjct: 644 LMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIY 703 Query: 885 CKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFY---------- 934 K+ H I + R K++V+ Q+PP+ + I S + Y Sbjct: 704 EKERIAHAKQIIKPFILRRVKEEVLK--QLPPKKDRIELCAMSEKQEQLYLGLFNRLKKS 761 Query: 935 ----HRQHEVCCQDVVVKLRKISDWAL 957 + E+C +V+++LRK+++ L Sbjct: 762 INNLEKNTEMC--NVMMQLRKMANHPL 786 Score = 34.3 bits (77), Expect = 1.1 Identities = 14/21 (66%), Positives = 18/21 (85%) Query: 367 LGGILADEMGLGKTVEVLALI 387 L GILADEMGLGKT++ +A + Sbjct: 516 LNGILADEMGLGKTIQAIAFL 536 >gi|190358532 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 isoform a [Homo sapiens] Length = 1028 Score = 60.8 bits (146), Expect = 1e-08 Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Query: 1527 QLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENL---SAFKRDPQINI 1583 +L+ G + ++FS + +LDI+ L + + ++ E + F D I + Sbjct: 867 ELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFV 926 Query: 1584 LLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIE 1643 LL G G+ + A V+L + NP ++ QA R HR+GQTK +V + + + TIE Sbjct: 927 FLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIE 986 Query: 1644 ERM 1646 E M Sbjct: 987 ESM 989 Score = 43.1 bits (100), Expect = 0.002 Identities = 57/269 (21%), Positives = 107/269 (39%), Gaps = 59/269 (21%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDG----FLQPHFLAEQDIVIITYDV 774 LI+ P+S W+ E+N + +L+VL Y G +++ F + ++++ TY+ Sbjct: 549 LIVVPASTIDNWLREVN--LWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNC 606 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 S +S+D R K AI DE M++ + Sbjct: 607 AIS----------SSDDRSLFRRLKLNYAI-------------FDEGHMLKNMGSIRYQH 643 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRP----------Y 884 ++ NR ++GTPVQ L +L L+ F+ + +R ++ Y Sbjct: 644 LMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIY 703 Query: 885 CKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFY---------- 934 K+ H I + R K++V+ Q+PP+ + I S + Y Sbjct: 704 EKERIAHAKQIIKPFILRRVKEEVLK--QLPPKKDRIELCAMSEKQEQLYLGLFNRLKKS 761 Query: 935 ------HRQHEVCCQDVVVKLRKISDWAL 957 + E+C +V+++LRK+++ L Sbjct: 762 INNLVTEKNTEMC--NVMMQLRKMANHPL 788 Score = 34.3 bits (77), Expect = 1.1 Identities = 14/21 (66%), Positives = 18/21 (85%) Query: 367 LGGILADEMGLGKTVEVLALI 387 L GILADEMGLGKT++ +A + Sbjct: 516 LNGILADEMGLGKTIQAIAFL 536 >gi|4885377 histone cluster 1, H1d [Homo sapiens] Length = 221 Score = 60.5 bits (145), Expect = 1e-08 Identities = 36/100 (36%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Query: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493 K K PP +I AV + GVS+ ++ K +++ YDV++N S +K LK L+ + Sbjct: 33 KRKASGPPVSELITKAVAASKERSGVSLAALKKALAAA-GYDVEKNNSRIKLGLKSLVSK 91 Query: 494 GLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRK 533 G + Q KG G SG+F L K + K KK PRK Sbjct: 92 GTLVQTKGTGASGSFKLNKKAASGEGKPKAKKAGAAKPRK 131 >gi|148612870 chromodomain helicase DNA binding protein 1-like [Homo sapiens] Length = 897 Score = 60.5 bits (145), Expect = 1e-08 Identities = 42/139 (30%), Positives = 64/139 (46%), Gaps = 4/139 (2%) Query: 1510 GSHSTKVEAVVRTLMKIQ--LRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKT 1567 G H T+ + L K+ L G + L+FS +LDI+ + + ++ Sbjct: 339 GDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVR 398 Query: 1568 FQENLSAFKRDPQ--INILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRI 1625 +E A K Q I + LL G G+ + A V+ V+ NP ++LQA R HRI Sbjct: 399 GEERHLAIKNFGQQPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRI 458 Query: 1626 GQTKPTIVHRFLIKATIEE 1644 GQ K V R + + T+EE Sbjct: 459 GQNKSVKVIRLIGRDTVEE 477 Score = 40.8 bits (94), Expect = 0.011 Identities = 42/224 (18%), Positives = 91/224 (40%), Gaps = 40/224 (17%) Query: 719 LIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQD---IVIITYDVL 775 LI+ P S+ W +E+ R + L + Y G K++ L ++ +++ TY++ Sbjct: 99 LILCPLSVLSNWKEEMQRF--APGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEIC 156 Query: 776 RSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMA 835 + ++ L + W + +DEA ++ + + Sbjct: 157 LKDASF--------------------------LKSFPWSVLVVDEAHRLKNQSSLLHKTL 190 Query: 836 QRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYC-----KKNPQ 890 S + ++GTP+Q L++L+ L+ F +EP V + Y ++ Sbjct: 191 SEFSVVFSLLLTGTPIQNSLQELYSLLSF--VEPDLFSKEEVGDFIQRYQDIEKESESAS 248 Query: 891 HLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFY 934 L+ + L R K +V ++P +TE + + S +++ +Y Sbjct: 249 ELHKLLQPFLLRRVKAEV--ATELPKKTEVVIYHGMSALQKKYY 290 Score = 31.6 bits (70), Expect = 6.8 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 8/45 (17%) Query: 352 TGCIIREYPNSGPQLL--------GGILADEMGLGKTVEVLALIL 388 TG +R Y G L G IL DEMGLGKT + +AL + Sbjct: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFI 86 >gi|6912622 RAD54 homolog B [Homo sapiens] Length = 910 Score = 58.9 bits (141), Expect = 4e-08 Identities = 46/174 (26%), Positives = 82/174 (47%), Gaps = 6/174 (3%) Query: 1513 STKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQI---SRVKTFQ 1569 S K++ + + L I P K ++ S + L+I+ + + + ++ + + Q Sbjct: 641 SGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQ 700 Query: 1570 ENLSAFK-RDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQT 1628 + + F + I LL G GL +I +H++L + NPA ++QA+ RV R GQ Sbjct: 701 QIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQK 760 Query: 1629 KPTIVHRFLIKATIEERM--QAMLKTAERSHTNSSAKHSEASVLTVADLADLFT 1680 P ++R L TIEE++ + + K K SE +V +L +LFT Sbjct: 761 YPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFT 814 Score = 43.1 bits (100), Expect = 0.002 Identities = 35/151 (23%), Positives = 69/151 (45%), Gaps = 30/151 (19%) Query: 716 RATLIISPSSICHQWVDEINRHVRSSSLRVL-VYQGVKKDGFLQPHFLAEQDIVIITYDV 774 + TLI++P S+ + W E + + S +++ V Q K + F++ F + ++II+Y++ Sbjct: 356 KKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYS---VLIISYEM 412 Query: 775 LRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEM 834 L L+ +++N K + I DE ++ +K Sbjct: 413 LLRSLD-------------QIKNIKFDLLI-------------CDEGHRLKNSAIKTTTA 446 Query: 835 AQRLSGINRWCISGTPVQRGLEDLFGLVVFL 865 LS R ++GTP+Q L++ F L+ F+ Sbjct: 447 LISLSCEKRIILTGTPIQNDLQEFFALIDFV 477 Score = 34.3 bits (77), Expect = 1.1 Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 6/48 (12%) Query: 368 GGILADEMGLGKTVEVLALILT------HTRQDVKQDALTLPEGKVVN 409 G ILADEMGLGKT++ ++LI T + + V + L + G +VN Sbjct: 321 GAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVN 368 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,212,368 Number of Sequences: 37866 Number of extensions: 2994865 Number of successful extensions: 10657 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 70 Number of HSP's successfully gapped in prelim test: 146 Number of HSP's that attempted gapping in prelim test: 10206 Number of HSP's gapped (non-prelim): 534 length of query: 1687 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1571 effective length of database: 13,855,062 effective search space: 21766302402 effective search space used: 21766302402 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.