Guide to the Human Genome
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Search of human proteins with 111548650

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111548650 family with sequence similarity 170, member A
[Homo sapiens]
         (329 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111548650 family with sequence similarity 170, member A [Homo...   672   0.0  
gi|169194829 PREDICTED: family with sequence similarity 170, mem...   110   2e-24
gi|89031947 PREDICTED: family with sequence similarity 170, memb...   110   2e-24
gi|37550464 PREDICTED: family with sequence similarity 170, memb...   110   2e-24
gi|194097454 hypothetical protein LOC284680 [Homo sapiens]             57   2e-08
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]               43   3e-04
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]               43   3e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        41   0.001
gi|17975763 myelin transcription factor 1 [Homo sapiens]               40   0.002
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    40   0.002
gi|118600967 shroom family member 4 [Homo sapiens]                     40   0.003
gi|21735415 centromere protein B [Homo sapiens]                        40   0.004
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    40   0.004
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    39   0.005
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    39   0.008
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    38   0.011
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    38   0.011
gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]                  38   0.011
gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]                   38   0.011
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              38   0.011
gi|21450836 zinc finger with UFM1-specific peptidase domain [Hom...    38   0.011
gi|169217548 PREDICTED: hypothetical protein [Homo sapiens]            38   0.014
gi|239752637 PREDICTED: hypothetical protein [Homo sapiens]            38   0.014
gi|113420837 PREDICTED: hypothetical protein [Homo sapiens]            38   0.014
gi|221219020 NYD-SP11 protein [Homo sapiens]                           37   0.019
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]             37   0.019
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]             37   0.019
gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]            37   0.019
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa...    37   0.019
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            37   0.024

>gi|111548650 family with sequence similarity 170, member A [Homo
           sapiens]
          Length = 329

 Score =  672 bits (1735), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MKRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSC 60
           MKRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSC
Sbjct: 1   MKRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSC 60

Query: 61  VSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCVN 120
           VSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCVN
Sbjct: 61  VSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCVN 120

Query: 121 KEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRN 180
           KEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRN
Sbjct: 121 KEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRN 180

Query: 181 LLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTM 240
           LLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTM
Sbjct: 181 LLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTM 240

Query: 241 EALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEE 300
           EALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEE
Sbjct: 241 EALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEE 300

Query: 301 GQPTEEDLGLRRSWSQCPGCVFHSPKDRN 329
           GQPTEEDLGLRRSWSQCPGCVFHSPKDRN
Sbjct: 301 GQPTEEDLGLRRSWSQCPGCVFHSPKDRN 329


>gi|169194829 PREDICTED: family with sequence similarity 170, member
           B [Homo sapiens]
          Length = 321

 Score =  110 bits (274), Expect = 2e-24
 Identities = 69/233 (29%), Positives = 111/233 (47%), Gaps = 10/233 (4%)

Query: 80  PQPQSPLAQVQERG----ETPPRSQHVSLSSYSSYKTCVSSLCV--NKEERGMKIYYMQV 133
           P+ +      ++RG     + P S+     SYS Y++C S +C   N   + +  +Y  V
Sbjct: 92  PREEGLYFAARDRGMRDWSSSPSSESSEYQSYSQYQSCCSCMCDEDNAAPQSVCAFYTHV 151

Query: 134 QMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKE 193
           Q  +GVAV+WETE   E + ++PR+ E    +  R      ++++   +     + +   
Sbjct: 152 QTVRGVAVAWETEAGFEPVTRKPRIHEAQFIKRQRWNGSSFEMASNTDMRWDLEACKSNC 211

Query: 194 HEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIRE 253
             E  + D L         P    PDWLVT   G RC+ACCRV  +++AL EH Q GIRE
Sbjct: 212 SPEPEDIDLLECCLQELREP----PDWLVTTNYGVRCVACCRVLPSLDALLEHAQHGIRE 267

Query: 254 GFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
           GFSC +F   M +          Q  +EE++ ++  E  +P+ +    Q  E+
Sbjct: 268 GFSCQIFFEEMLERRRAQGQAHDQQLEEEQSPSDNSECSRPQGEVLSAQQQEK 320


>gi|89031947 PREDICTED: family with sequence similarity 170, member
           B [Homo sapiens]
          Length = 321

 Score =  110 bits (274), Expect = 2e-24
 Identities = 69/233 (29%), Positives = 111/233 (47%), Gaps = 10/233 (4%)

Query: 80  PQPQSPLAQVQERG----ETPPRSQHVSLSSYSSYKTCVSSLCV--NKEERGMKIYYMQV 133
           P+ +      ++RG     + P S+     SYS Y++C S +C   N   + +  +Y  V
Sbjct: 92  PREEGLYFAARDRGMRDWSSSPSSESSEYQSYSQYQSCCSCMCDEDNAAPQSVCAFYTHV 151

Query: 134 QMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKE 193
           Q  +GVAV+WETE   E + ++PR+ E    +  R      ++++   +     + +   
Sbjct: 152 QTVRGVAVAWETEAGFEPVTRKPRIHEAQFIKRQRWNGSSFEMASNTDMRWDLEACKSNC 211

Query: 194 HEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIRE 253
             E  + D L         P    PDWLVT   G RC+ACCRV  +++AL EH Q GIRE
Sbjct: 212 SPEPEDIDLLECCLQELREP----PDWLVTTNYGVRCVACCRVLPSLDALLEHAQHGIRE 267

Query: 254 GFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
           GFSC +F   M +          Q  +EE++ ++  E  +P+ +    Q  E+
Sbjct: 268 GFSCQIFFEEMLERRRAQGQAHDQQLEEEQSPSDNSECSRPQGEVLSAQQQEK 320


>gi|37550464 PREDICTED: family with sequence similarity 170, member
           B [Homo sapiens]
          Length = 321

 Score =  110 bits (274), Expect = 2e-24
 Identities = 69/233 (29%), Positives = 111/233 (47%), Gaps = 10/233 (4%)

Query: 80  PQPQSPLAQVQERG----ETPPRSQHVSLSSYSSYKTCVSSLCV--NKEERGMKIYYMQV 133
           P+ +      ++RG     + P S+     SYS Y++C S +C   N   + +  +Y  V
Sbjct: 92  PREEGLYFAARDRGMRDWSSSPSSESSEYQSYSQYQSCCSCMCDEDNAAPQSVCAFYTHV 151

Query: 134 QMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKE 193
           Q  +GVAV+WETE   E + ++PR+ E    +  R      ++++   +     + +   
Sbjct: 152 QTVRGVAVAWETEAGFEPVTRKPRIHEAQFIKRQRWNGSSFEMASNTDMRWDLEACKSNC 211

Query: 194 HEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIRE 253
             E  + D L         P    PDWLVT   G RC+ACCRV  +++AL EH Q GIRE
Sbjct: 212 SPEPEDIDLLECCLQELREP----PDWLVTTNYGVRCVACCRVLPSLDALLEHAQHGIRE 267

Query: 254 GFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
           GFSC +F   M +          Q  +EE++ ++  E  +P+ +    Q  E+
Sbjct: 268 GFSCQIFFEEMLERRRAQGQAHDQQLEEEQSPSDNSECSRPQGEVLSAQQQEK 320


>gi|194097454 hypothetical protein LOC284680 [Homo sapiens]
          Length = 261

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 174 SDVSTRNLLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMAC 233
           S+    N+ S S         E   +S     S T +D   A    W    +NG++C+AC
Sbjct: 131 SEDMAENICSSSSSPENTCPREATKKSRHGLDSITSQDILMASR--WHPAQQNGYKCVAC 188

Query: 234 CRVFTTMEALQEHVQFGIREGFSCHVFHLTMAQL 267
           CR++ T++ L+ H++ G REGFSC V++  +  L
Sbjct: 189 CRMYPTLDFLKSHIKRGFREGFSCKVYYRKLKAL 222


>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
          Length = 111

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 18/38 (47%), Positives = 27/38 (71%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
           G  E+++  DE+EEE G E+EEEE+ + +EE+G   EE
Sbjct: 45  GEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEE 82



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKP-EAKEEEGQPTEED 307
           A   GN E+E   +++ +   +E+EEE    E +EEEG   EED
Sbjct: 33  APANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEED 76



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)

Query: 272 ESESTQDEQEEENGNEKEE--EEKPEAKEEEGQPTEED 307
           E E  ++E+EEE G+ +EE  +E  EA+   G+   ED
Sbjct: 57  EEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAED 94



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 13/44 (29%), Positives = 22/44 (50%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRR 312
           G  E E  + + EEE+G+E EE E    K       ++D+  ++
Sbjct: 61  GEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKK 104



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 11/36 (30%), Positives = 22/36 (61%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           ++ +  + + EENG ++ + E  E +EE G+  EE+
Sbjct: 32  DAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEE 67


>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
          Length = 110

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 18/38 (47%), Positives = 27/38 (71%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
           G  E+++  DE+EEE G E+EEEE+ + +EE+G   EE
Sbjct: 44  GEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEE 81



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKP--EAKEEEGQPTEED 307
           A   GN   E+   EQE +N  ++EEEE    E +EEEG   EED
Sbjct: 33  APANGNANEEN--GEQEADNEVDEEEEEGGEEEEEEEEGDGEEED 75



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)

Query: 272 ESESTQDEQEEENGNEKEE--EEKPEAKEEEGQPTEED 307
           E E  ++E+EEE G+ +EE  +E  EA+   G+   ED
Sbjct: 56  EEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAED 93



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 13/44 (29%), Positives = 22/44 (50%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRR 312
           G  E E  + + EEE+G+E EE E    K       ++D+  ++
Sbjct: 60  GEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKK 103


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 18/42 (42%), Positives = 28/42 (66%)

Query: 266 QLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           Q  G  E E  ++++EEE  +E+EEEE+ E +EEE +  EE+
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 18/36 (50%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  +DE+EEE   E+EEEE+ E +EEE +  EE+
Sbjct: 735 EEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 17/36 (47%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E   +E+EEE+  E+EEEE+ E +EEE +  EE+
Sbjct: 736 EEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 18/46 (39%), Positives = 27/46 (58%)

Query: 262 LTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           L   Q   N + E  ++E++EE   E EEEE+ E +EEE +  EE+
Sbjct: 722 LAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEE 767



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 20/56 (35%), Positives = 30/56 (53%)

Query: 252 REGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           R GFS  +       L       + ++E+EEE  +E+EEEE  E +EEE +  EE+
Sbjct: 707 RVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEE 762



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 18/38 (47%), Positives = 23/38 (60%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLG 309
           E E  +DE+EEE   E+EEEE+ E +EEE       LG
Sbjct: 742 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALG 779



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLR 311
           E +  ++E+EEE   E+EEEE+ E +        E LG R
Sbjct: 746 EEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPR 785


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 18/36 (50%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  +DE+EEE   E+EEEE+ E +EEE +  EE+
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 18/41 (43%), Positives = 28/41 (68%)

Query: 267 LTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           L+   E E  ++E+EEE  +E+EEEE+ E +EEE +  EE+
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEE 295



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 17/36 (47%), Positives = 26/36 (72%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  ++E+EEE+  E+EEEE+ E +EEE +  EE+
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 17/36 (47%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  ++E+EEE   E+EEEE+ E +EEE +  EE+
Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 17/36 (47%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  ++E+EEE   E+EEEE+ E +EEE +  EE+
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 18/51 (35%), Positives = 28/51 (54%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRSWSQCPGCVF 322
           E E  ++E+EE+   E+EEEE+ E +EEE +  EE+          P  +F
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIF 313



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 16/36 (44%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           + E  ++E+EEE   E+EEEE+ E +EEE +  EE+
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 16/39 (41%), Positives = 25/39 (64%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G +  E   +E+EEE   E+E+EE+ E +EEE +  EE+
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 12/29 (41%), Positives = 18/29 (62%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEE 300
           E E  ++E+EEE   E+EEE  P+   +E
Sbjct: 287 EEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 19/39 (48%), Positives = 26/39 (66%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGL 310
           E E  ++EQEEE   E++EEE+ E +EEE +  EE L L
Sbjct: 861 EEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSL 899



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 16/41 (39%), Positives = 27/41 (65%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLG 309
           G  +   +++E+EEE   E+EEEE+ + +EEE +  EE+ G
Sbjct: 852 GGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKG 892



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 15/39 (38%), Positives = 26/39 (66%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G+ E E  ++E++EE   E+E+EE+ E +EEE +   E+
Sbjct: 857 GDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 15/48 (31%), Positives = 26/48 (54%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRSWSQ 316
           G    E  ++E+E+E   E+EE+E+ E +EEE +    +  L   W +
Sbjct: 856 GGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPE 903



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 11/36 (30%), Positives = 22/36 (61%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           + +  +D    + G+ +EEEE+ E +EEE +  E++
Sbjct: 844 DEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQE 879


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 20/56 (35%), Positives = 33/56 (58%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRSWSQCPGCVFHSPKD 327
            + +  Q +QEEE   E+EEEE+ E +EEE +  EE+L  +   S+  G    +P++
Sbjct: 1123 QQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEE 1178



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 15/36 (41%), Positives = 23/36 (63%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            + +  Q +Q+EE   E+EEEE+ E +EEE    EE+
Sbjct: 1122 KQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEE 1157


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 20/45 (44%), Positives = 32/45 (71%), Gaps = 2/45 (4%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLG 309
           A +T +++SE  ++E+EEE   E+EEE + E +EEEG+  EE+ G
Sbjct: 395 ATITTSLKSEGEEEEEEEEE--EEEEEGEGEEEEEEGEEEEEEGG 437



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/35 (51%), Positives = 24/35 (68%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
           E E  ++E+EEE G  +EEEE+ E +EEEG   EE
Sbjct: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEE 441



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 18/43 (41%), Positives = 25/43 (58%)

Query: 263 TMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTE 305
           T  +  G  E E  ++E+EEE   E+EEEE  E +EE G+  E
Sbjct: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEE 441



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 23/120 (19%)

Query: 184 DSEPSGEEKEHEERTESDSLPGSPTVEDTPRA--KTPDWLVTMENGFRCMACCRVFTTME 241
           + E  GEE+E EE  + DS       E++     +  DW   +               +E
Sbjct: 438 EGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV---------------VE 482

Query: 242 ALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEG 301
           A      +G +E   C   H     L G  +S+S  D +EE++  E +E+E  +  EE+G
Sbjct: 483 AGGSFGAYGAQEEAQCPTLHF----LEGGEDSDS--DSEEEDDEEEDDEDEDDDDDEEDG 536



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G  E E  + E+EEE G E EE  + E  EEEG    ++
Sbjct: 420 GEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 272 ESESTQDEQEEENGNEKEEE--EKPEAKEEEGQPTEEDL 308
           E E  + E+EEE G E+EEE  E  E  EEE    E D+
Sbjct: 416 EEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 17/37 (45%), Positives = 27/37 (72%)

Query: 271  MESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            +  ES+++E+EEE+  E+EEEE+ E  EEE +  EE+
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEE 1100



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 17/41 (41%), Positives = 28/41 (68%)

Query: 273  SESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRS 313
            SE  ++E++EE   E+EEEE+ E +EEE +  EE+  ++ S
Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 17/44 (38%), Positives = 26/44 (59%)

Query: 264  MAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            + +L+     E  ++E EEE   E+EEEE  E +EEE +  EE+
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 15/37 (40%), Positives = 26/37 (70%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDL 308
            E E  ++++EEE   E+EEE++ E +EEE +  EE++
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENI 1106



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 17/42 (40%), Positives = 27/42 (64%)

Query: 266  QLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            QL    +  S ++E+EE+   E+EEEE+ E +EEE +  EE+
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 15/39 (38%), Positives = 25/39 (64%)

Query: 262  LTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEE 300
            L +++ +   E E   +E+EEE   E+E+EE+ E +EEE
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEE 1100



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 14/24 (58%), Positives = 19/24 (79%)

Query: 278  DEQEEENGNEKEEEEKPEAKEEEG 301
            +E+EEE   E+EEEE+ E +EEEG
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEG 1374



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 14/31 (45%), Positives = 21/31 (67%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQ 302
            + E  ++E+EEE   E+EEEE+ E +EE  Q
Sbjct: 1077 DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 14/31 (45%), Positives = 21/31 (67%)

Query: 277  QDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            ++E+EEE   E+EEEE+   +EE G   E+D
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKD 1381



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 12/32 (37%), Positives = 20/32 (62%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQP 303
            E E  ++E+EE+   E+EEEE+ E +  +  P
Sbjct: 1079 EEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 12/32 (37%), Positives = 19/32 (59%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQP 303
            E E  ++E+E+E   E+EEEE+ E   +   P
Sbjct: 1080 EEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 17/63 (26%), Positives = 26/63 (41%)

Query: 139  VAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKEHEERT 198
            + +  E +ET E+L  Q           V   T P +    +L+   E   EE+E EE  
Sbjct: 1305 IRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEE 1364

Query: 199  ESD 201
            E +
Sbjct: 1365 EEE 1367


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 26/70 (37%), Positives = 42/70 (60%), Gaps = 8/70 (11%)

Query: 240 MEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQE--EENGNEKEEEEKPEAK 297
           +E+L++   F +  G S  +FH     L G  E+E  ++++E  EE G E+EEEE+ E +
Sbjct: 84  LESLEDFEHF-LMSGES--LFHYP---LVGEEETEREEEDEEIQEEGGEEEEEEEEEEEE 137

Query: 298 EEEGQPTEED 307
           EEE +  EE+
Sbjct: 138 EEEEEEEEEE 147



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 38/143 (26%), Positives = 54/143 (37%), Gaps = 35/143 (24%)

Query: 168 RVGTPPSDVSTRNLLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENG 227
           R G  P+D ST N  SD E + E+ E E            ++ED        +L++ E+ 
Sbjct: 58  RDGGFPNDASTENRSSDQESASEDIELE------------SLEDFEH-----FLMSGESL 100

Query: 228 FRCMACCRVFTTMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNE 287
           F         T  E   E +Q                    G  E E  ++E+EEE   E
Sbjct: 101 FHYPLVGEEETEREEEDEEIQE------------------EGGEEEEEEEEEEEEEEEEE 142

Query: 288 KEEEEKPEAKEEEGQPTEEDLGL 310
           +EEEE+P A  +      E   L
Sbjct: 143 EEEEEQPRAGPQGSGGNHEQYSL 165


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 64/310 (20%), Positives = 117/310 (37%), Gaps = 60/310 (19%)

Query: 2   KRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSCV 61
           K+++ +K  + E+ ++  EK  G SK+   A+Q    ++ +   +   E     +    +
Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEEL 372

Query: 62  SSSRKLIHSGIQ-RIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCV- 119
            + RK      Q +  R   + +    ++++ G+   +SQ  + +   +    + +  V 
Sbjct: 373 EAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVE 432

Query: 120 --NKEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVS 177
             +K+    K    + +  K +    E++E  ES      ME     EV+  G P  + +
Sbjct: 433 VPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES------MELCAAVEVMEQGVPEKEET 486

Query: 178 TRNLLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVF 237
                    P   E E EE TE   L               DW                 
Sbjct: 487 ---------PPPVEPEEEEDTEDAGLD--------------DW----------------- 506

Query: 238 TTMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAK 297
              EA+    +    EG   H+      ++  N E E  ++E+EEE+  E EEEE+ E +
Sbjct: 507 ---EAMASDEETEKVEGNKVHI------EVKENPEEEEEEEEEEEED-EESEEEEEEEGE 556

Query: 298 EEEGQPTEED 307
            E  +  EED
Sbjct: 557 SEGSEGDEED 566



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 14/126 (11%)

Query: 196 ERTESDSLPGS-PTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIREG 254
           E    DSLP   P  ED  R K P  L + E       C  V    + + E  +      
Sbjct: 432 EVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEE--TPPP 489

Query: 255 FSCHVFHLTMAQLTGNMESESTQDEQEEENGN-----------EKEEEEKPEAKEEEGQP 303
                   T      + E+ ++ +E E+  GN           E+EEEE+ E ++EE + 
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549

Query: 304 TEEDLG 309
            EE+ G
Sbjct: 550 EEEEEG 555



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 49/217 (22%), Positives = 85/217 (39%), Gaps = 26/217 (11%)

Query: 2   KRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCS-- 59
           ++R+++K  E E  +   ++G  ++KSQ +A       +    +QGV EV S        
Sbjct: 385 EKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGV-EVPSKDSLPKKR 443

Query: 60  --CVSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERG-----ETPP-----RSQHVSLSSY 107
                  RK I   ++              +V E+G     ETPP       +    +  
Sbjct: 444 PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL 503

Query: 108 SSYKTCVSSLCVNKEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVV 167
             ++   S     K E G K+ +++V+ N       E EE  E  E+    EE    E  
Sbjct: 504 DDWEAMASDEETEKVE-GNKV-HIEVKENPE-----EEEEEEEEEEEDEESEEEEEEEGE 556

Query: 168 RVGTPPSDVSTRNLLSDSEPSGE--EKEHEERTESDS 202
             G+   +   +  +SD + SG+  +K+  +   SDS
Sbjct: 557 SEGSEGDEEDEK--VSDEKDSGKTLDKKPSKEMSSDS 591


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 16/35 (45%), Positives = 24/35 (68%)

Query: 273  SESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            +E  ++E EEE G E++EEEK E +EE  Q  E++
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDE 1906



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 17/37 (45%), Positives = 22/37 (59%)

Query: 269  GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTE 305
            G  E E  ++E EEE   EKE+EEK E +  EG+  E
Sbjct: 1884 GEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEE 1920



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 17/40 (42%), Positives = 26/40 (65%)

Query: 268  TGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            T   E E  ++E EEE+  EKEE+E+  A+E+E +  EE+
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEE 1911



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 16/42 (38%), Positives = 26/42 (61%)

Query: 266  QLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            Q+   +E E   +E+EEE+  E+ EEE  E KEE+ + T ++
Sbjct: 1861 QILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQE 1902



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
            E E  + E+E+E   E++EEE  + KE+E +  EE
Sbjct: 1878 EDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 272  ESESTQDEQEEENGNEK--EEEEKPEAKEEEGQPTEEDLGLRRSWSQ 316
            E    +DE+E+E   E+  +E+E  E +EEE    E++ GL     Q
Sbjct: 1882 EEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQ 1928


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 16/35 (45%), Positives = 24/35 (68%)

Query: 273  SESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            +E  ++E EEE G E++EEEK E +EE  Q  E++
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDE 1906



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 17/37 (45%), Positives = 22/37 (59%)

Query: 269  GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTE 305
            G  E E  ++E EEE   EKE+EEK E +  EG+  E
Sbjct: 1884 GEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEE 1920



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 17/40 (42%), Positives = 26/40 (65%)

Query: 268  TGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            T   E E  ++E EEE+  EKEE+E+  A+E+E +  EE+
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEE 1911



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 16/42 (38%), Positives = 26/42 (61%)

Query: 266  QLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            Q+   +E E   +E+EEE+  E+ EEE  E KEE+ + T ++
Sbjct: 1861 QILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQE 1902



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
            E E  + E+E+E   E++EEE  + KE+E +  EE
Sbjct: 1878 EDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 272  ESESTQDEQEEENGNEK--EEEEKPEAKEEEGQPTEEDLGLRRSWSQ 316
            E    +DE+E+E   E+  +E+E  E +EEE    E++ GL     Q
Sbjct: 1882 EEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQ 1928


>gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
          Length = 337

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 18/43 (41%), Positives = 28/43 (65%)

Query: 266 QLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDL 308
           Q+ G  ++ S +DE EEE+ ++ EEE+K +   E+GQ  EE L
Sbjct: 233 QVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPL 275


>gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
          Length = 376

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 18/43 (41%), Positives = 28/43 (65%)

Query: 266 QLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDL 308
           Q+ G  ++ S +DE EEE+ ++ EEE+K +   E+GQ  EE L
Sbjct: 272 QVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPL 314


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 8/67 (11%)

Query: 241 EALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEE 300
           E LQE     + EGF+       +A L+ + + E  ++ +EEE   E+EEEE  E +EEE
Sbjct: 339 EQLQE-----VLEGFN---MAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEE 390

Query: 301 GQPTEED 307
            +  EE+
Sbjct: 391 EEEEEEE 397



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 14/33 (42%), Positives = 19/33 (57%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPT 304
           E E  +DE+EEE   E+EEEE  +  + E   T
Sbjct: 377 EEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSAT 409



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 12/31 (38%), Positives = 20/31 (64%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQ 302
           E+E  ++E EEE   E+EEEE+   +  +G+
Sbjct: 375 EAEEEEEEDEEEEEEEEEEEEEEPQQRGQGE 405


>gi|21450836 zinc finger with UFM1-specific peptidase domain [Homo
           sapiens]
          Length = 578

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 41/170 (24%), Positives = 66/170 (38%), Gaps = 22/170 (12%)

Query: 144 ETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKEHEERTESDSL 203
           E+ + L+S EKQ  + E+  S      +PP          +    G+ +EH E  E+   
Sbjct: 125 ESRKFLKSREKQSSLTEIKGSVYETTYSPP----------ECPFCGKIEEHSEDMETHVK 174

Query: 204 PGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIREGFSCHVFHLT 263
                + D P       L      + C  C  + T    LQEHV   + E    + F   
Sbjct: 175 TKHANLLDIPLEDCDQPL------YDCPMCGLICTNYHILQEHVDLHLEE----NSFQQG 224

Query: 264 MAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRS 313
           M ++  + + +     Q+EE+   + EE + E   EE Q  +   GL  S
Sbjct: 225 MDRVQCSGDLQLAHQLQQEEDRKRRSEESRQEI--EEFQKLQRQYGLDNS 272


>gi|169217548 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 15/39 (38%), Positives = 27/39 (69%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G  E+++  DE+ EE+G E+EEE++ + +EE+G   E +
Sbjct: 44  GEQEADNEVDEEGEESGEEEEEEKEGDGEEEDGDEEEAE 82



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 16/43 (37%), Positives = 22/43 (51%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           A   GN   E+ + E + E   E EE  + E +E+EG   EED
Sbjct: 33  APANGNANEENGEQEADNEVDEEGEESGEEEEEEKEGDGEEED 75


>gi|239752637 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 15/39 (38%), Positives = 27/39 (69%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G  E+++  DE+ EE+G E+EEE++ + +EE+G   E +
Sbjct: 44  GEQEADNEVDEEGEESGEEEEEEKEGDGEEEDGDEEEAE 82



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 16/43 (37%), Positives = 22/43 (51%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           A   GN   E+ + E + E   E EE  + E +E+EG   EED
Sbjct: 33  APANGNANEENGEQEADNEVDEEGEESGEEEEEEKEGDGEEED 75


>gi|113420837 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 15/39 (38%), Positives = 27/39 (69%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G  E+++  DE+ EE+G E+EEE++ + +EE+G   E +
Sbjct: 44  GEQEADNEVDEEGEESGEEEEEEKEGDGEEEDGDEEEAE 82



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 16/43 (37%), Positives = 22/43 (51%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           A   GN   E+ + E + E   E EE  + E +E+EG   EED
Sbjct: 33  APANGNANEENGEQEADNEVDEEGEESGEEEEEEKEGDGEEED 75


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 260  FHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLG 309
            F   M  L   +E + +   +EEE   E+EE E+ E +EEE +  EE+ G
Sbjct: 2226 FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG 2275



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 15/36 (41%), Positives = 22/36 (61%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            E    ++E+EEE   E+EEE K E + EE Q  +E+
Sbjct: 2249 EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284



 Score = 32.0 bits (71), Expect = 0.78
 Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 4/39 (10%)

Query: 272  ESESTQDEQEEENGNEKEEEE----KPEAKEEEGQPTEE 306
            E E  ++E+ EE   EKEEEE    K E K+EE Q  EE
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 14/41 (34%), Positives = 24/41 (58%)

Query: 267  LTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            L+   E E  ++E+ EE    +EEEE+ E +E E +  E++
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE 2283



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 2/35 (5%)

Query: 270  NMESESTQDEQEEENGNEKE--EEEKPEAKEEEGQ 302
            ++ SE  ++ +EEE   E+E  EEE+   +EEEG+
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEE 306
            E E  Q E+EEE   +K++E+K E  +E+ +  EE
Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEE 2308



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 12/36 (33%), Positives = 23/36 (63%)

Query: 272  ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
            E E  ++E+EE    E+ EE++ E +EEE +  +++
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293


>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
          Length = 1123

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 9/71 (12%)

Query: 239 TMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQD--EQEEENGNEKEEEEKPEA 296
           T E L E  +  + EG       LTM +  G+ ESESTQ+  E+E+E  + +EEE+  + 
Sbjct: 553 TEEELTEQQEVLLGEGA------LTMPR-EGSTESESTQEDLEEEDEEDDGEEEEDCIQV 605

Query: 297 KEEEGQPTEED 307
           K+EEG+   E+
Sbjct: 606 KDEEGESGAEE 616


>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
          Length = 1122

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 9/71 (12%)

Query: 239 TMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQD--EQEEENGNEKEEEEKPEA 296
           T E L E  +  + EG       LTM +  G+ ESESTQ+  E+E+E  + +EEE+  + 
Sbjct: 552 TEEELTEQQEVLLGEGA------LTMPR-EGSTESESTQEDLEEEDEEDDGEEEEDCIQV 604

Query: 297 KEEEGQPTEED 307
           K+EEG+   E+
Sbjct: 605 KDEEGESGAEE 615


>gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 15/39 (38%), Positives = 26/39 (66%)

Query: 269 GNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           G  E++   DE+ EE+G E+EEE++ + +EE+G   E +
Sbjct: 44  GEQEADKEVDEEGEESGEEEEEEKEGDGEEEDGDEEEAE 82



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 16/43 (37%), Positives = 23/43 (53%)

Query: 265 AQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           A   GN   E+ + E ++E   E EE  + E +E+EG   EED
Sbjct: 33  APANGNANEENGEQEADKEVDEEGEESGEEEEEEKEGDGEEED 75


>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
           sapiens]
          Length = 528

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 20/56 (35%), Positives = 30/56 (53%)

Query: 257 CHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRR 312
           CH+F   +A      E +  + ++EEE    +EEE +   KEEE +  EE+  LRR
Sbjct: 169 CHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRR 224



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 14/36 (38%), Positives = 21/36 (58%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  +  Q+EE    +EEEE+   +EEE +  EE+
Sbjct: 200 EEEERERLQKEEEKRRREEEERLRREEEERRRIEEE 235


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 16/36 (44%), Positives = 25/36 (69%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  ++E+EEE   ++EEEEK E KEE+ +  E++
Sbjct: 127 EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 18/36 (50%), Positives = 25/36 (69%), Gaps = 2/36 (5%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E E  +DE+EEE   EKEE+E  E +E+EG+  EE+
Sbjct: 136 EEEKEEDEEEEEKEEEKEEDE--EEEEKEGKKMEEE 169



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 16/34 (47%), Positives = 23/34 (67%)

Query: 274 ESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           E  ++ +EEE   EKEE+E+ E KEEE +  EE+
Sbjct: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 16/38 (42%), Positives = 24/38 (63%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLG 309
           E E  ++E++EE   E EEEE+ E ++EE +  EE  G
Sbjct: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEG 163



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 13/37 (35%), Positives = 25/37 (67%)

Query: 271 MESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEED 307
           +E E  + E+EE+   ++E+EE+ E +EE+ +  EE+
Sbjct: 123 VEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEE 159



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 14/42 (33%), Positives = 27/42 (64%)

Query: 272 ESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRS 313
           E E  ++++EE+  +E+EEE++ +  EEE    E D  ++R+
Sbjct: 141 EDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRT 182


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.124    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,315,900
Number of Sequences: 37866
Number of extensions: 794437
Number of successful extensions: 16933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 351
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 8992
Number of HSP's gapped (non-prelim): 5125
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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