Guide to the Human Genome
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Search of human proteins with 169184624

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo
sapiens]
         (267 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo sapi...   562   e-161
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 147   1e-35
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 147   1e-35
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          49   5e-06
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    47   2e-05
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       46   4e-05
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       46   4e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        43   3e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    42   4e-04
gi|197276661 paired box 1 [Homo sapiens]                               42   6e-04
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                42   7e-04
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 42   7e-04
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 42   7e-04
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 42   7e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    41   0.001
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  40   0.002
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     40   0.002
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    40   0.002
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    40   0.002
gi|22538470 eomesodermin [Homo sapiens]                                40   0.003
gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239754253 PREDICTED: hypothetical protein XP_002345936 [Homo ...    40   0.003
gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo ...    40   0.003
gi|239748791 PREDICTED: hypothetical protein XP_002346804 [Homo ...    40   0.003
gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo ...    40   0.003
gi|239742828 PREDICTED: hypothetical protein XP_002342673 [Homo ...    40   0.003
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       40   0.003
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]                      40   0.003
gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens]         40   0.003
gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens]         40   0.003

>gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo
           sapiens]
          Length = 267

 Score =  562 bits (1449), Expect = e-161
 Identities = 267/267 (100%), Positives = 267/267 (100%)

Query: 1   MAALGLALRKCQKGFPFQKTSHYPTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWL 60
           MAALGLALRKCQKGFPFQKTSHYPTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWL
Sbjct: 1   MAALGLALRKCQKGFPFQKTSHYPTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWL 60

Query: 61  RPLHPGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPP 120
           RPLHPGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPP
Sbjct: 61  RPLHPGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPP 120

Query: 121 GLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAA 180
           GLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAA
Sbjct: 121 GLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAA 180

Query: 181 QPQPPRPARPACGSSPMAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGT 240
           QPQPPRPARPACGSSPMAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGT
Sbjct: 181 QPQPPRPARPACGSSPMAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGT 240

Query: 241 PAMATTAASSGQRDRPCQPHARTQLSR 267
           PAMATTAASSGQRDRPCQPHARTQLSR
Sbjct: 241 PAMATTAASSGQRDRPCQPHARTQLSR 267


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  147 bits (370), Expect = 1e-35
 Identities = 71/71 (100%), Positives = 71/71 (100%)

Query: 197 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 256
           MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 1   MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60

Query: 257 CQPHARTQLSR 267
           CQPHARTQLSR
Sbjct: 61  CQPHARTQLSR 71


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  147 bits (370), Expect = 1e-35
 Identities = 71/71 (100%), Positives = 71/71 (100%)

Query: 197 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 256
           MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 1   MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60

Query: 257 CQPHARTQLSR 267
           CQPHARTQLSR
Sbjct: 61  CQPHARTQLSR 71


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 58/230 (25%), Positives = 82/230 (35%), Gaps = 46/230 (20%)

Query: 28  PEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLH-------PGAEGSQTRPSGAPQF 80
           P  PE S G    ++G    PH       G  LRP         PGAE S +     P  
Sbjct: 482 PRPPEPSQGPSTTSSGGGTGPH----PPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGG 537

Query: 81  TTLLALAAGSPWRPWRPG--------PALAGALRFPGAHGRLCAPPPPGLGLGQGR---- 128
            T      G+  +P  PG        PA                P PP +G         
Sbjct: 538 DTAQTPKPGTS-QPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPAT 596

Query: 129 --AGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALR---DGLAAQPQ 183
              G    P    S P+P       P +GTS++      +PT P G      +   +QP 
Sbjct: 597 PGGGTAQTPEAGTSQPMP-------PGMGTSTSH-----QPTTPGGGTAQTPEPGTSQPM 644

Query: 184 PPRPARPACGSSPMAEQLALVI-----GGTIGGLLLLLLIGASCCLWRRF 228
           P   + P+ G  P  ++   V+     GG +G LLLL L+G +  + + +
Sbjct: 645 PLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHY 694


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 52/167 (31%), Positives = 62/167 (37%), Gaps = 24/167 (14%)

Query: 26  PPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFTTLLA 85
           PPP+    S G        +  P  GG   +G   RP  P  EG    P G  Q      
Sbjct: 81  PPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP--EGPP--PQGGNQ------ 130

Query: 86  LAAGSPWRPWRP-GPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPLP 144
            + G P RP +P GP   G  +  G       PP PG   G    G     +  G  P P
Sbjct: 131 -SQGPPPRPGKPEGPPPQGGNQSQG------PPPRPGKPEGPPPQGGN---QSQGPPPHP 180

Query: 145 CTARLPAPQLGTSSTTDRPCARPTAPRG-ALRDGLAAQPQPPRPARP 190
                P PQ G  S    P  RP  P G   + G  +Q  PPRP +P
Sbjct: 181 GKPEGPPPQGGNQS--QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 225



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 57/188 (30%), Positives = 66/188 (35%), Gaps = 40/188 (21%)

Query: 26  PPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGA-EGSQTRPSGAPQFTTLL 84
           PPP+    S G        +  P  GG   +G    P HPG  EG    P G  Q     
Sbjct: 144 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP---PPHPGKPEGPP--PQGGNQ----- 193

Query: 85  ALAAGSPWRPWRP-GPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPL 143
             + G P RP +P GP   G  +  G       PP PG   G    G G +P+G    P 
Sbjct: 194 --SQGPPPRPGKPEGPPPQGGNQSQGP------PPRPGKPEGPPSQG-GNKPQGPP--PH 242

Query: 144 PCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQPP---------------RPA 188
           P   + P PQ G       P  RP  P      G   QP PP               RP 
Sbjct: 243 PGKPQGPPPQEGNKPQRPPPPGRPQGPPPP--GGNPQQPLPPPAGKPQGPPPPPQGGRPH 300

Query: 189 RPACGSSP 196
           RP  G  P
Sbjct: 301 RPPQGQPP 308


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 31/185 (16%)

Query: 14  GFPFQKTSHYPTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTR 73
           G P  +    PT  P+QP   +    +  G  + P  GG            P A  S  R
Sbjct: 501 GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP----PAARPPASPSPQR 556

Query: 74  PSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGL 133
            +G PQ T   +++  +P       P  +GA              PPG   GQ R G   
Sbjct: 557 QAGPPQATRQTSVSGPAP-------PKASGA--------------PPG---GQQRQGPPQ 592

Query: 134 RPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQP--PRPARPA 191
           +P G        +   P P+ G   TT +P      P G  +  LA +P    P PA  A
Sbjct: 593 KPPGPAGPTRQASQAGPVPRTG-PPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAA 651

Query: 192 CGSSP 196
            G  P
Sbjct: 652 AGGPP 656



 Score = 33.1 bits (74), Expect = 0.26
 Identities = 38/135 (28%), Positives = 48/135 (35%), Gaps = 9/135 (6%)

Query: 66  GAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLG 125
           G+ G    P   P         AG P +  RP P   G    PG   +   PP       
Sbjct: 431 GSHGQTPSPGALPLGRQTSQQPAGPPAQQ-RPPPQ--GGPPQPGPGPQRQGPPLQQRPPP 487

Query: 126 QGRAG-AGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQP 184
           QG+   +GL P     LP     RLP+P         +  A PT  +G     +A  P  
Sbjct: 488 QGQQHLSGLGPPAGSPLP----QRLPSPTSAPQQPASQ-AAPPTQGQGRQSRPVAGGPGA 542

Query: 185 PRPARPACGSSPMAE 199
           P  ARP    SP  +
Sbjct: 543 PPAARPPASPSPQRQ 557


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 31/185 (16%)

Query: 14  GFPFQKTSHYPTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTR 73
           G P  +    PT  P+QP   +    +  G  + P  GG            P A  S  R
Sbjct: 501 GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP----PAARPPASPSPQR 556

Query: 74  PSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGL 133
            +G PQ T   +++  +P       P  +GA              PPG   GQ R G   
Sbjct: 557 QAGPPQATRQTSVSGPAP-------PKASGA--------------PPG---GQQRQGPPQ 592

Query: 134 RPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQP--PRPARPA 191
           +P G        +   P P+ G   TT +P      P G  +  LA +P    P PA  A
Sbjct: 593 KPPGPAGPTRQASQAGPVPRTG-PPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAA 651

Query: 192 CGSSP 196
            G  P
Sbjct: 652 AGGPP 656



 Score = 33.1 bits (74), Expect = 0.26
 Identities = 38/135 (28%), Positives = 48/135 (35%), Gaps = 9/135 (6%)

Query: 66  GAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLG 125
           G+ G    P   P         AG P +  RP P   G    PG   +   PP       
Sbjct: 431 GSHGQTPSPGALPLGRQTSQQPAGPPAQQ-RPPPQ--GGPPQPGPGPQRQGPPLQQRPPP 487

Query: 126 QGRAG-AGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQP 184
           QG+   +GL P     LP     RLP+P         +  A PT  +G     +A  P  
Sbjct: 488 QGQQHLSGLGPPAGSPLP----QRLPSPTSAPQQPASQ-AAPPTQGQGRQSRPVAGGPGA 542

Query: 185 PRPARPACGSSPMAE 199
           P  ARP    SP  +
Sbjct: 543 PPAARPPASPSPQRQ 557


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 34/97 (35%), Positives = 42/97 (43%), Gaps = 17/97 (17%)

Query: 97   PGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGT 156
            PG A A  LR            PPG GLG GRA AG RP      P P + RLPA     
Sbjct: 1198 PGSATAADLR---------PKQPPGRGLGPGRAQAGARP------PAPRSPRLPASTSAA 1242

Query: 157  SSTTDRPCARPTAPRGALRDGLAAQP--QPPRPARPA 191
             + +  P ++  + R +      A+P   PPR   PA
Sbjct: 1243 RNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPPA 1279


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 24/179 (13%)

Query: 24   PTPPPEQPEYSSG--AIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFT 81
            PTPP   P    G  A     G    P     + +G    P H GA  +      +P+  
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 82   TLLALAAGSPWRPWRPGPALAGALRFPGAHGR----LCAPPPPGLGLGQGRAGAGLRPRG 137
                   G+P  P    P+  G L  P   G        PP P  GL      A   P+G
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL------ATPSPKG 1193

Query: 138  AGSLPLPCTARLPAPQLGTSSTTDR-----PCARPTAPRGALRDGLAAQPQPPRPARPA 191
            A + P    A  P+P+ G ++ + +     P A P +P+G    GLA       P  PA
Sbjct: 1194 APTTP---AATPPSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPSPKGAPTTPA 1245



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 53/188 (28%), Positives = 75/188 (39%), Gaps = 23/188 (12%)

Query: 20   TSHYPTPPPEQ--PEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGA 77
            T+H PTPP  +  P  S+   +   GV   P    +T     +    P  EG  T    A
Sbjct: 852  TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPK---ETPTPSVVNLPFP-KEGPATP---A 904

Query: 78   PQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAG-AGLRPR 136
            P+    L++ + SP +  R  PA  G    P   G   AP PP       + G A   P+
Sbjct: 905  PKQAPALSMTSSSPKKA-RATPAPKGIPASPSPKG---APTPPAATPPSPKGGPATPSPK 960

Query: 137  GAGSLPLPCTARLPAPQLGTSSTTDR-----PCARPTAPRGA-LRDGLAAQPQPPRPARP 190
             A   P P  A  P+P+ G ++ + +     P A P +P+G          P PP    P
Sbjct: 961  WA---PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 191  ACGSSPMA 198
            +   SP A
Sbjct: 1018 SPKGSPAA 1025



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 47/189 (24%), Positives = 64/189 (33%), Gaps = 33/189 (17%)

Query: 24   PTPPPEQPEYSSGAIMEAAGVDAMPHWG----GQTLEGEWLRPLHPGAEGSQTRPSGAPQ 79
            PTPP   P    G     +     P W       T       P  P  +G+ T P+  P 
Sbjct: 940  PTPPAATPPSPKGGPATPS-----PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994

Query: 80   FTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGA- 138
                     G P  P   G     A+  P   G   A P P  G     A     P+G+ 
Sbjct: 995  SPK------GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK-GASTPPAATPPSPKGSP 1047

Query: 139  GSLPLPC------TARLPAPQLGTSSTTDR-----PCARPTAPRGALRDGLAAQPQPPRP 187
             + PLP        A LP+P+ G ++ + +     P A P +P+G       A P P   
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG-----PATPSPKGA 1102

Query: 188  ARPACGSSP 196
              P   + P
Sbjct: 1103 PMPPAATPP 1111



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 42/182 (23%), Positives = 64/182 (35%), Gaps = 15/182 (8%)

Query: 24   PTPPPEQPEYSSGAIMEAA--GVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFT 81
            PT P   P    G +   +  G    P     + +G    P   GA  +      +P+  
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231

Query: 82   TLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRP-RGAGS 140
                   G+P  P    P+  G    P   G   AP PP       + G    P +GA  
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKG---APTPPAATPPSLKGGLATPPHKGA-- 1286

Query: 141  LPLPCTARLPAPQLGTSSTTDR-----PCARPTAPRGAL-RDGLAAQPQPPRPARPACGS 194
             P P     P+P+ G +++  +     P A P +P+G+         P PP    P+   
Sbjct: 1287 -PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 195  SP 196
            +P
Sbjct: 1346 TP 1347


>gi|197276661 paired box 1 [Homo sapiens]
          Length = 534

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 38/119 (31%), Positives = 51/119 (42%), Gaps = 16/119 (13%)

Query: 98  GPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGL---RPRGAGSLPLPCTARLPAPQL 154
           G  LA    +P A G   APP  G+ +  G   A +    P   GSLP P       P+ 
Sbjct: 384 GGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREGSLPAPAAR----PRT 439

Query: 155 GTSSTTDRPCARPTAPRGALRDGLAAQPQPPRPARPACGSSPMAEQLALVIG-GTIGGL 212
            + + TD P +RP  PRG+     A + +   P    C ++P        IG G IGGL
Sbjct: 440 PSVAYTDCP-SRPRPPRGSSPRTRARRERQADPGAQVCAAAP-------AIGTGRIGGL 490



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 44/152 (28%), Positives = 58/152 (38%), Gaps = 23/152 (15%)

Query: 23  YPTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFTT 82
           Y  P P  P  + G  +   G     H GG+       +  HP  EGS   P+  P+  +
Sbjct: 386 YLAPGPPWPP-AQGPPLAPPGAGVAVH-GGELAAAMTFK--HPSREGSLPAPAARPRTPS 441

Query: 83  LLALAAGSPWRPWRPGPALAGALR----FPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGA 138
           +      S  RP R       A R     PGA  ++CA  P    +G GR G GL    A
Sbjct: 442 VAYTDCPSRPRPPRGSSPRTRARRERQADPGA--QVCAAAP---AIGTGRIG-GLAEEEA 495

Query: 139 GSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
            + P    AR  +PQ        +PC  P  P
Sbjct: 496 SAGPR--GARPASPQA-------QPCLWPDPP 518


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 56/182 (30%), Positives = 63/182 (34%), Gaps = 22/182 (12%)

Query: 24  PTPPPEQPEYSSGAIMEAAGVDAMPHWGG-QTLEGEWLRPLHPGAEG-------SQTRPS 75
           P  PP  P  S   I    G   +P   G Q   G    P  PG  G        Q    
Sbjct: 157 PPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLP 216

Query: 76  GAPQFTTLLALAAGSPWRPWRPGPA---LAGALRFPGAHGRLCAPPPPGLGLGQGRAGA- 131
           GAP          G+P  P  PGPA     G    PGA G      PPG+   +G  GA 
Sbjct: 217 GAPG-------QGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAV 269

Query: 132 -GLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCAR-PTAPRGALRDGLAAQPQPPRPAR 189
               P G   + +P  A LP PQ G S     P  R P    G    G+   P P     
Sbjct: 270 GPKGPPGVDGVGVPGAAGLPGPQ-GPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRG 328

Query: 190 PA 191
           PA
Sbjct: 329 PA 330



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 47/157 (29%), Positives = 54/157 (34%), Gaps = 21/157 (13%)

Query: 55  LEGEWLRPLHPGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPA------LAGALRFP 108
           L+GE   P  PG  G    P G P F     +  G P    +PGPA        G    P
Sbjct: 75  LKGEPGPPGKPGPRG----PPGPPGFPGKPGM--GKPGLHGQPGPAGPPGFSRMGKAGPP 128

Query: 109 GAHGRLCAPPPPGLGLGQG-RAGAGLR-PRGAGSLPLPCTARLP-------APQLGTSST 159
           G  G++  P  PGL    G R   GLR P G   LP P    +P        P       
Sbjct: 129 GLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQG 188

Query: 160 TDRPCARPTAPRGALRDGLAAQPQPPRPARPACGSSP 196
              P   P  P      G     QP  P  P  G +P
Sbjct: 189 EPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP 225



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%)

Query: 65  PGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPA-LAGALRFPGAHGRLCAPPPPGLG 123
           PG +G +  P G P          G P      GP+ LAG    PG  G   A  PPG  
Sbjct: 375 PGPKG-EAGPGGPP----------GVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPT 423

Query: 124 LGQGRAGAGLRPRG---AGSLPLPCTARLPAPQLGTSSTTDRP----CARPTAPRGALRD 176
             +G  G   RP G   AG+L       LP  Q G    +  P     A P  P+G    
Sbjct: 424 GPKGEPGFTGRPGGPGVAGALGQKGDLGLPG-QPGLRGPSGIPGLQGPAGPIGPQGL--P 480

Query: 177 GLAAQPQPPRP 187
           GL  +P  P P
Sbjct: 481 GLKGEPGLPGP 491


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 47/160 (29%), Positives = 55/160 (34%), Gaps = 30/160 (18%)

Query: 61  RPLHPGAEGSQTRPSGAPQ-----FTTLLALAAGSPWR--------PWR--PGPALAGAL 105
           RP H    G    P G P        +L     G P +        PW   P P +    
Sbjct: 377 RPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436

Query: 106 RFPGAHGRLCAPPPPGLGLGQGRAGAGLRP--RGAGSLPLPCTARLPAPQLGTSSTTDRP 163
             PG HG    PPP    LG    G+G+    +G G +P P    +P P    S      
Sbjct: 437 HPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP--- 489

Query: 164 CARPTAPRGALRDGLAAQPQPPRPARPACGSSPMAEQLAL 203
              P  P G L      Q QPP P  P   SS MA    L
Sbjct: 490 ---PPPPSGPLPPWQQQQQQPPPPPPP---SSSMASSTPL 523


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%)

Query: 61  RPLHPGAEGSQTRPSGAPQ-----FTTLLALAAGSPWR--------PWR--PGPALAGAL 105
           RP H    G    P G P        +L     G P +        PW   P P +    
Sbjct: 377 RPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436

Query: 106 RFPGAHGRLCAPPPPGLGLGQGRAGAGLRP--RGAGSLPLPCTARLPAPQLGTSSTTDRP 163
             PG HG    PPP    LG    G+G+    +G G +P P    +P P    S     P
Sbjct: 437 HPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492

Query: 164 CARPTAPRGALRDGLAAQPQPPRPARPACGSSPMAEQ 200
              P+ P    +      P PP P+     S+P+  Q
Sbjct: 493 ---PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ 526


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%)

Query: 61  RPLHPGAEGSQTRPSGAPQ-----FTTLLALAAGSPWR--------PWR--PGPALAGAL 105
           RP H    G    P G P        +L     G P +        PW   P P +    
Sbjct: 377 RPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436

Query: 106 RFPGAHGRLCAPPPPGLGLGQGRAGAGLRP--RGAGSLPLPCTARLPAPQLGTSSTTDRP 163
             PG HG    PPP    LG    G+G+    +G G +P P    +P P    S     P
Sbjct: 437 HPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492

Query: 164 CARPTAPRGALRDGLAAQPQPPRPARPACGSSPMAEQ 200
              P+ P    +      P PP P+     S+P+  Q
Sbjct: 493 ---PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ 526



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 40/157 (25%), Positives = 52/157 (33%), Gaps = 36/157 (22%)

Query: 16  PFQKTSHYPTPPPEQP-----------EYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLH 64
           P+Q+    P PPP              + ++     +AG  ++P W  Q           
Sbjct: 499 PWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA----AS 554

Query: 65  PGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPP---- 120
           PGA   Q  P+  P     L      P  P  P P        PG+ G + APPPP    
Sbjct: 555 PGAPQMQGNPTMVP-----LPPGVQPPLPPGAPPPPPPPP---PGSAGMMYAPPPPPPPP 606

Query: 121 ----GLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQ 153
                     G   AG+ P G    P P     P PQ
Sbjct: 607 MDPSNFVTMMGMGVAGMPPFGMPPAPPP-----PPPQ 638


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 60/188 (31%), Positives = 70/188 (37%), Gaps = 31/188 (16%)

Query: 24  PTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFTTL 83
           P PPP Q   +   + +AA +   P    + L G    PL  G+     RP   P     
Sbjct: 716 PPPPPPQVTSAIATLQQAAAMSFCPQVA-RPLVG----PLALGSPRLVRRPPPGP----- 765

Query: 84  LALAAGSPWRPWRPGPALAGALRFPGA-----HGRLCAPPPPGLGLGQGRAGAGLRPRGA 138
            A AA SP  P  P  +  GA   P A     +G L A P  G  L   R     RP  A
Sbjct: 766 -APAAASPGPP--PPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSA 822

Query: 139 GSLPLPCTARLPAPQLGT---SSTTDR----PCARPTAPRGALRD----GLAAQPQPPRP 187
               LP  A  P P   T   SS+T R    P AR  AP    RD    G A    P   
Sbjct: 823 SQPSLPHGA--PGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQDS 880

Query: 188 ARPACGSS 195
           AR    S+
Sbjct: 881 ARSRLSSN 888


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 55/212 (25%), Positives = 73/212 (34%), Gaps = 46/212 (21%)

Query: 24   PTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFTTL 83
            P PPP +P  +     + A +  +P       EGE  +P  P         S  P  T  
Sbjct: 1193 PPPPPAEPPPT-----DLAHLPPLP-----PPEGEARKPAKPPV-------SPKPVLTQP 1235

Query: 84   LALAAGSPWRPWR----PGPALAGALRFPGAHGR----LCAPPPPGLGLGQGRAGAGLRP 135
            +    GSP    +    PGP   G+     AHG        PPPP       +A AGL  
Sbjct: 1236 VPKLQGSPTPTSKKVPLPGP---GSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPS 1292

Query: 136  RGAGSLPLPCTARLPAPQL----GTSSTTDRPCARPTAP--------------RGALRDG 177
              AG  P P  AR P   L    GT  +     A+P +P                A    
Sbjct: 1293 GSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAA 1352

Query: 178  LAAQPQPPRPARPACGSSPMAEQLALVIGGTI 209
             AA P PP  A P   +    E+ +  +   +
Sbjct: 1353 AAAPPAPPEGASPGDSARQKLEETSACLAAAL 1384


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 40/125 (32%), Positives = 50/125 (40%), Gaps = 12/125 (9%)

Query: 64  HPGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPG-PALAGALRFPGAHGRLCAPPPPGL 122
           H G +G + +P GAP          G P  P   G P   GA   PG  GR+ AP P G 
Sbjct: 182 HNGLDGLKGQP-GAPG-------VKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGA 233

Query: 123 GLGQGRAGAGLRPRG-AGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGAL-RDGLAA 180
               G  G  + P G  GS   P     P P+    +  +   A P  PRG +   GL+ 
Sbjct: 234 RGSDGSVGP-VGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSG 292

Query: 181 QPQPP 185
              PP
Sbjct: 293 PVGPP 297



 Score = 34.7 bits (78), Expect = 0.089
 Identities = 44/167 (26%), Positives = 57/167 (34%), Gaps = 19/167 (11%)

Query: 51  GGQTLEGEWLRPLHPGAEGSQ-TRPSGAPQFTTLLALAAGSPWRPWRPGP---------- 99
           G + L GE  R   PG  G++ +  S  P        +AG P  P  PGP          
Sbjct: 214 GARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA 273

Query: 100 ------ALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQ 153
                    G +  PG  G +  P  PG     G  GA   P  AG+  LP    +P P 
Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333

Query: 154 LGTSSTTDRPCARPTAPRGALRDGLAAQPQPPRPARPACGSSPMAEQ 200
               +T  R       P G+   G +     P  A P     P  E+
Sbjct: 334 GAAGATGARGLVGEPGPAGS--KGESGNKGEPGSAGPQGPPGPSGEE 378



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 34/109 (31%), Positives = 38/109 (34%), Gaps = 14/109 (12%)

Query: 87  AAGSPWRPWRPGPALA-------GALRFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAG 139
           AAG       PGPA +       G   FPGA GR   P P G+    G  G    P G  
Sbjct: 761 AAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPG----PAGKE 816

Query: 140 SLPLPCTARLPAPQLGTSSTTDRP-CARPTAPRGALRDGLAAQPQPPRP 187
            L  P   + P  + G       P  A    P G    G A  P  P P
Sbjct: 817 GLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSG--EAGTAGPPGTPGP 863


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 2/121 (1%)

Query: 73   RPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAG 132
            RP+  P        A+   WR  +      GA    G H       P GLGLG G A A 
Sbjct: 924  RPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYYGPIEPQGLGLGLGEARAA 983

Query: 133  LRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQPPRPARPAC 192
              PRGA   PL   A  P  +   S         P  P      G  + P PP  A  A 
Sbjct: 984  --PRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPPAAAATAV 1041

Query: 193  G 193
            G
Sbjct: 1042 G 1042



 Score = 29.3 bits (64), Expect = 3.8
 Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 15/60 (25%)

Query: 69  GSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGR 128
           G    P G  +   LLALA  SP+    PGP  AG                PG GLG  R
Sbjct: 5   GGPRGPRGPAKMLLLLALACASPFPEEAPGPGGAGG---------------PGGGLGGAR 49


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 44/139 (31%), Positives = 48/139 (34%), Gaps = 7/139 (5%)

Query: 65  PGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFP---GAHGRLCAPPPPG 121
           PG  G    P   P   T      G P  P  PGP   G +  P   G   R   PPPP 
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277

Query: 122 LGLGQ--GRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLA 179
           L  GQ  G+   G  P G    P+P     P P          P   P  P G L   L 
Sbjct: 278 LFPGQPFGQPPLGPLPPGPPP-PVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336

Query: 180 AQPQPPRPARPACGSSPMA 198
             P P  P  P  G+ P A
Sbjct: 337 LAPPPHLPGPPP-GAPPPA 354



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 42/127 (33%), Positives = 47/127 (37%), Gaps = 12/127 (9%)

Query: 75  SGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPPPGLGLGQGRAGAGLR 134
           +G P  ++  A   G   R   PG A+ G  RFPG  G     PPP    GQ      L 
Sbjct: 186 AGPPGGSSRAAFPQGGRGRGRFPG-AVPGGDRFPGPAGP--GGPPPPFPAGQTPPRPPLG 242

Query: 135 PRGAGSLPLPCTAR--LPAPQLGTSSTTDR---PCARPTAPRGALRDGLAAQPQPPRPAR 189
           P G    P P      LP P  G  +  DR   P   P  P G    G    P PP P  
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG----PLPPGPPP 298

Query: 190 PACGSSP 196
           P  G  P
Sbjct: 299 PVPGYGP 305


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 40/144 (27%), Positives = 53/144 (36%), Gaps = 12/144 (8%)

Query: 24  PTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFTTL 83
           P    E P  ++ A   AA   A   +   +L  E      PG +GS+     AP     
Sbjct: 108 PCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSEL---AAPCSLFP 164

Query: 84  LALAAGSPWRPWRPGPALA----GALRFPGAHGRLCAPP-----PPGLGLGQGRAGAGLR 134
              AAG+P  P  P P  A    G++  PG       PP      PG G G G  G+   
Sbjct: 165 YQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGG 224

Query: 135 PRGAGSLPLPCTARLPAPQLGTSS 158
             G G+      A L  P  G ++
Sbjct: 225 GGGPGTYQYSQGAPLYGPYPGAAA 248


>gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 180

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 48/152 (31%), Positives = 57/152 (37%), Gaps = 37/152 (24%)

Query: 65  PGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPA------LAGALRFPGAHGRLCAPP 118
           PGA G+  RP   P      A     P +PWRPGP        A +   PG+  R  A P
Sbjct: 48  PGAPGALGRPK--PVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105

Query: 119 --------PPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
                   PP   + +     G RP G         +R P PQ GT    D P      P
Sbjct: 106 APPRCSRRPPTTTVSRVAPSPG-RPAGLH------RSREPRPQDGTPPPVDTP------P 152

Query: 171 RGALRDGLAAQPQPPRPARPACGSS-PMAEQL 201
           R        A+P+P    RP  GS  P  EQL
Sbjct: 153 R-------TARPRPAFTPRPVVGSERPRQEQL 177



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 106 RFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCA 165
           R PGA G L  P P   G   G      +P   G L  P   R P+  +  S++  RP A
Sbjct: 46  RPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSAS--RPTA 103

Query: 166 RPTAPRGALRDGLAAQPQ-PPRPARPA 191
            P  PR + R       +  P P RPA
Sbjct: 104 TPAPPRCSRRPPTTTVSRVAPSPGRPA 130


>gi|239754253 PREDICTED: hypothetical protein XP_002345936 [Homo
           sapiens]
          Length = 145

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 112 GRLCAPPPPGLGLGQGRAGAGL-RPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
           G  C+P PP     +  +G G  RPRG     +   A LP+           P A PTAP
Sbjct: 3   GVCCSPAPPDEARSRAWSGCGCPRPRGEVRRAVARLAALPSAHHTALHLPPVPAAPPTAP 62

Query: 171 RGALRDGLAAQPQPP-----RPARPACGSSPMAEQLALVIGGTIG 210
            G  R   A +   P      P  P+  ++P+  +      GT+G
Sbjct: 63  PGFQRGPGARKRSAPSAMLLEPPHPSAAAAPLQRRRRTPPPGTVG 107


>gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo
           sapiens]
          Length = 180

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 48/152 (31%), Positives = 57/152 (37%), Gaps = 37/152 (24%)

Query: 65  PGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPA------LAGALRFPGAHGRLCAPP 118
           PGA G+  RP   P      A     P +PWRPGP        A +   PG+  R  A P
Sbjct: 48  PGAPGALGRPK--PVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105

Query: 119 --------PPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
                   PP   + +     G RP G         +R P PQ GT    D P      P
Sbjct: 106 APPRCSRRPPTTTVSRVAPSPG-RPAGLH------RSREPRPQDGTPPPVDTP------P 152

Query: 171 RGALRDGLAAQPQPPRPARPACGSS-PMAEQL 201
           R        A+P+P    RP  GS  P  EQL
Sbjct: 153 R-------TARPRPAFTPRPVVGSERPRQEQL 177



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 106 RFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCA 165
           R PGA G L  P P   G   G      +P   G L  P   R P+  +  S++  RP A
Sbjct: 46  RPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSAS--RPTA 103

Query: 166 RPTAPRGALRDGLAAQPQ-PPRPARPA 191
            P  PR + R       +  P P RPA
Sbjct: 104 TPAPPRCSRRPPTTTVSRVAPSPGRPA 130


>gi|239748791 PREDICTED: hypothetical protein XP_002346804 [Homo
           sapiens]
          Length = 145

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 112 GRLCAPPPPGLGLGQGRAGAGL-RPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
           G  C+P PP     +  +G G  RPRG     +   A LP+           P A PTAP
Sbjct: 3   GVCCSPAPPDEARSRAWSGCGCPRPRGEVRRAVARLAALPSAHHTALHLPPVPAAPPTAP 62

Query: 171 RGALRDGLAAQPQPP-----RPARPACGSSPMAEQLALVIGGTIG 210
            G  R   A +   P      P  P+  ++P+  +      GT+G
Sbjct: 63  PGFQRGPGARKRSAPSAMLLEPPHPSAAAAPLQRRRRTPPPGTVG 107


>gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo
           sapiens]
          Length = 180

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 48/152 (31%), Positives = 57/152 (37%), Gaps = 37/152 (24%)

Query: 65  PGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPA------LAGALRFPGAHGRLCAPP 118
           PGA G+  RP   P      A     P +PWRPGP        A +   PG+  R  A P
Sbjct: 48  PGAPGALGRPK--PVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105

Query: 119 --------PPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
                   PP   + +     G RP G         +R P PQ GT    D P      P
Sbjct: 106 APPRCSRRPPTTTVSRVAPSPG-RPAGLH------RSREPRPQDGTPPPVDTP------P 152

Query: 171 RGALRDGLAAQPQPPRPARPACGSS-PMAEQL 201
           R        A+P+P    RP  GS  P  EQL
Sbjct: 153 R-------TARPRPAFTPRPVVGSERPRQEQL 177



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 106 RFPGAHGRLCAPPPPGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCA 165
           R PGA G L  P P   G   G      +P   G L  P   R P+  +  S++  RP A
Sbjct: 46  RPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSAS--RPTA 103

Query: 166 RPTAPRGALRDGLAAQPQ-PPRPARPA 191
            P  PR + R       +  P P RPA
Sbjct: 104 TPAPPRCSRRPPTTTVSRVAPSPGRPA 130


>gi|239742828 PREDICTED: hypothetical protein XP_002342673 [Homo
           sapiens]
          Length = 145

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 112 GRLCAPPPPGLGLGQGRAGAGL-RPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAP 170
           G  C+P PP     +  +G G  RPRG     +   A LP+           P A PTAP
Sbjct: 3   GVCCSPAPPDEARSRAWSGCGCPRPRGEVRRAVARLAALPSAHHTALHLPPVPAAPPTAP 62

Query: 171 RGALRDGLAAQPQPP-----RPARPACGSSPMAEQLALVIGGTIG 210
            G  R   A +   P      P  P+  ++P+  +      GT+G
Sbjct: 63  PGFQRGPGARKRSAPSAMLLEPPHPSAAAAPLQRRRRTPPPGTVG 107


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 48/175 (27%), Positives = 64/175 (36%), Gaps = 34/175 (19%)

Query: 24  PTPPPEQPEYSSGAIMEAAGVDAMPHWGGQTLEGEWLRPLHPGAEGSQTRPSGAPQFTTL 83
           P PPP+Q +            DA    G Q        P  P A  +  RPS   +    
Sbjct: 303 PGPPPKQADLP----------DAKDSPGPQ--------PTDPPASEAPDRPSKPER---- 340

Query: 84  LALAAGSPWRPWRPGPALAGALRFPGAHGRLC-APPPPGLGLGQGRAGAG-LRPRGAGSL 141
            A+    P  P R    + GA+  PG    L   P  PG  + +  +  G L+P  A   
Sbjct: 341 AAMNGADPISPQR----VRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEW 396

Query: 142 PLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQPPRPARPACGSSP 196
           P    +  PAP +   ST+ R   R T  R         QP PP P   +  S+P
Sbjct: 397 PGRPQSHPPAPPVQAPSTSRRGLIRVTTQRAL------GQPPPPEPTASSMASAP 445



 Score = 33.1 bits (74), Expect = 0.26
 Identities = 39/123 (31%), Positives = 49/123 (39%), Gaps = 23/123 (18%)

Query: 98  GPALAGA---------LRFPGAHGRLCAPPPPGLG----LGQG-RAGAGLRPRGAGSLPL 143
           GP+  GA         +R P   G+L  P     G    LG+G + G GL   G G  P 
Sbjct: 739 GPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGRGPQGGPGLSRNGVG--PA 796

Query: 144 PCTARL---PAPQLGTSSTTDRPCARPTAPRGAL--RDGLA--AQPQPPRPARPACGSSP 196
           P  + L   P   +  S + D    R    R ++  R GL   A P P    RP  GS P
Sbjct: 797 PSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFQRCGLRGLASPPPGGALRPRRGSHP 856

Query: 197 MAE 199
            AE
Sbjct: 857 KAE 859


>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
          Length = 904

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 9/137 (6%)

Query: 60  LRPLHPGAEGSQTRPSGAPQFTTLLALAAGSPWRPWRPGPALAGALRFPGAHGRLCAPPP 119
           L P  PGA G  +R S +PQ       A  S W P         A   P       AP P
Sbjct: 255 LVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEP--------AAGNSPARASVPAAPNP 306

Query: 120 PGLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLA 179
                      +  RP  +   P P   ++  P++  SS      A P     A    + 
Sbjct: 307 AATSATSVHVRSPARPSESRLAPTPTEGKV-RPRVTNSSPMGWSSAAPCTAAAASHPAVP 365

Query: 180 AQPQPPRPARPACGSSP 196
                PRPA P  G +P
Sbjct: 366 PSAPDPRPATPQGGGAP 382



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 17/57 (29%), Positives = 25/57 (43%)

Query: 142 PLPCTARLPAPQLGTSSTTDRPCARPTAPRGALRDGLAAQPQPPRPARPACGSSPMA 198
           P P TA +P+ Q  T +    P A+P         GL ++ +PP P   +  S   A
Sbjct: 474 PSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASA 530


>gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens]
          Length = 530

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 39/127 (30%), Positives = 49/127 (38%), Gaps = 12/127 (9%)

Query: 121 GLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSST-TDRPCARPTAPRGALRDGLA 179
           G G      G G   RGA   P P  +   A ++   +T TD    +P+ P   L D L+
Sbjct: 12  GSGSWHSERGEG---RGARPQPTPSGSMQQANKVSLKATWTDAESKQPSQPLPDLADHLS 68

Query: 180 AQP----QPPRPAR---PACGSSPMAEQLALVIGGT-IGGLLLLLLIGASCCLWRRFCAT 231
           AQ     +P RPA    P    SP  E     I  T IG    L         W RFC  
Sbjct: 69  AQATALARPRRPASLTPPRADPSPSKESDQTAIDQTAIGSYYQLFAAAVGNVEWLRFCLN 128

Query: 232 LTYEELP 238
            +  E+P
Sbjct: 129 QSLREIP 135


>gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens]
          Length = 343

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 39/127 (30%), Positives = 49/127 (38%), Gaps = 12/127 (9%)

Query: 121 GLGLGQGRAGAGLRPRGAGSLPLPCTARLPAPQLGTSST-TDRPCARPTAPRGALRDGLA 179
           G G      G G   RGA   P P  +   A ++   +T TD    +P+ P   L D L+
Sbjct: 12  GSGSWHSERGEG---RGARPQPTPSGSMQQANKVSLKATWTDAESKQPSQPLPDLADHLS 68

Query: 180 AQP----QPPRPAR---PACGSSPMAEQLALVIGGT-IGGLLLLLLIGASCCLWRRFCAT 231
           AQ     +P RPA    P    SP  E     I  T IG    L         W RFC  
Sbjct: 69  AQATALARPRRPASLTPPRADPSPSKESDQTAIDQTAIGSYYQLFAAAVGNVEWLRFCLN 128

Query: 232 LTYEELP 238
            +  E+P
Sbjct: 129 QSLREIP 135


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,708,038
Number of Sequences: 37866
Number of extensions: 985464
Number of successful extensions: 7218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 817
Number of HSP's that attempted gapping in prelim test: 5801
Number of HSP's gapped (non-prelim): 2041
length of query: 267
length of database: 18,247,518
effective HSP length: 100
effective length of query: 167
effective length of database: 14,460,918
effective search space: 2414973306
effective search space used: 2414973306
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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