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Search of human proteins with 167614504
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167614504 laminin, beta 1 precursor [Homo sapiens]
(1786 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 3761 0.0
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 1946 0.0
gi|143770880 laminin, beta 4 [Homo sapiens] 1456 0.0
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 424 e-118
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 424 e-118
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 424 e-118
gi|93204871 netrin 4 [Homo sapiens] 366 e-101
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 340 7e-93
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 307 7e-83
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 306 2e-82
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 306 2e-82
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 291 3e-78
gi|21264602 laminin alpha 5 [Homo sapiens] 283 8e-76
gi|219842266 usherin isoform B [Homo sapiens] 277 8e-74
gi|219842259 usherin isoform A [Homo sapiens] 277 8e-74
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 266 1e-70
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 266 1e-70
gi|148613884 netrin 1 [Homo sapiens] 254 4e-67
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 199 2e-50
gi|5453810 netrin 3 [Homo sapiens] 198 4e-50
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 172 3e-42
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 171 4e-42
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 171 4e-42
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 169 3e-41
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 167 6e-41
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 167 6e-41
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 162 3e-39
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 161 6e-39
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 159 2e-38
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 152 2e-36
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 3761 bits (9754), Expect = 0.0
Identities = 1786/1786 (100%), Positives = 1786/1786 (100%)
Query: 1 MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHK 60
MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHK
Sbjct: 1 MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHK 60
Query: 61 PEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVEN 120
PEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVEN
Sbjct: 61 PEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVEN 120
Query: 121 VTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTG 180
VTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTG
Sbjct: 121 VTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTG 180
Query: 181 PMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKL 240
PMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKL
Sbjct: 181 PMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKL 240
Query: 241 HTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMC 300
HTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMC
Sbjct: 241 HTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMC 300
Query: 301 RHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGG 360
RHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGG
Sbjct: 301 RHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGG 360
Query: 361 VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTG 420
VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTG
Sbjct: 361 VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTG 420
Query: 421 LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY 480
LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY
Sbjct: 421 LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY 480
Query: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC
Sbjct: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Query: 541 NEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFF 600
NEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFF
Sbjct: 541 NEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFF 600
Query: 601 IDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPG 660
IDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPG
Sbjct: 601 IDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPG 660
Query: 661 SRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGG 720
SRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGG
Sbjct: 661 SRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGG 720
Query: 721 SGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGS 780
SGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGS
Sbjct: 721 SGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGS 780
Query: 781 LSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC 840
LSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC
Sbjct: 781 LSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC 840
Query: 841 HCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLA 900
HCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLA
Sbjct: 841 HCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLA 900
Query: 901 GYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCAS 960
GYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCAS
Sbjct: 901 GYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCAS 960
Query: 961 GYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA 1020
GYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA
Sbjct: 961 GYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA 1020
Query: 1021 LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG 1080
LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG
Sbjct: 1021 LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG 1080
Query: 1081 CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIE 1140
CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIE
Sbjct: 1081 CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIE 1140
Query: 1141 TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRF 1200
TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRF
Sbjct: 1141 TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRF 1200
Query: 1201 LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV 1260
LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV
Sbjct: 1201 LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV 1260
Query: 1261 TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS 1320
TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS
Sbjct: 1261 TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS 1320
Query: 1321 ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE 1380
ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE
Sbjct: 1321 ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE 1380
Query: 1381 LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA 1440
LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA
Sbjct: 1381 LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA 1440
Query: 1441 WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL 1500
WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL
Sbjct: 1441 WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL 1500
Query: 1501 RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI 1560
RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI
Sbjct: 1501 RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI 1560
Query: 1561 LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI 1620
LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI
Sbjct: 1561 LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI 1620
Query: 1621 QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK 1680
QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK
Sbjct: 1621 QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK 1680
Query: 1681 QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL 1740
QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL
Sbjct: 1681 QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL 1740
Query: 1741 KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL 1786
KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL
Sbjct: 1741 KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL 1786
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 1946 bits (5041), Expect = 0.0
Identities = 899/1785 (50%), Positives = 1214/1785 (68%), Gaps = 15/1785 (0%)
Query: 7 LAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI 66
L S LA A+ A + GC+ GSCYPATGDLL+GRA +L+ +STCGL+ P+PYCI
Sbjct: 22 LLLSVLAATLAQAPAPDVP---GCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCI 78
Query: 67 VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLD 126
VSHLQ++KKCF+C+S+ P+ NP SH I+NVVT+FAP R WWQSENG+ VTIQLD
Sbjct: 79 VSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLD 138
Query: 127 LEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVD 186
LEAEFHFTHLIMTFKTFRPAAML+ERS+DFG+TW VYRYF+YDC A FPG+ P + D
Sbjct: 139 LEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWD 198
Query: 187 DIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDN 246
D++C+SRYS+IEPSTEGEVI+R LDPA I DPYS RIQNLLKITNLR+ +LHTLGDN
Sbjct: 199 DVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDN 258
Query: 247 LLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKG 306
LLD R EIREKYYYA+Y++VVRGNCFCYGHASECAP G EGMVHG C+C+HNT+G
Sbjct: 259 LLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRG 318
Query: 307 LNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQ 366
LNCE C DFY DLPWRPAE +S+AC+KC C+ H+ SCHFDMAVYLA+GNVSGGVCD CQ
Sbjct: 319 LNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQ 378
Query: 367 HNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC 426
HNT GR+CE C+PF+Y+ P +D+RDP C C CDP GSQ+ G CDS+ D + GL++GQC
Sbjct: 379 HNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQC 438
Query: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVT 486
RCK +V G C C++GF+ LS D GC+ C CN GT+PG PCD +G CYCKRLVT
Sbjct: 439 RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVT 498
Query: 487 GQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPG 546
G+ CD+CLP HWGLS+DL GCRPCDCD+GGAL+ C +GQC CR HM+GR+C +V+PG
Sbjct: 499 GRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPG 558
Query: 547 YYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPY 606
Y+ LDH ++EAE+ G + +VER PSWTG+GFVR+ EG LEF + ++P
Sbjct: 559 YFRPFLDHLIWEAEDTR-GQVLDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPK 617
Query: 607 SMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVL 666
+M+YD+L+R EPQ+P+ W + + VQRPG +P S CG+ +P DD +L P +RY++
Sbjct: 618 AMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPKDDRIQGTLQPHARYLIF 677
Query: 667 PRPVCFEKGTNYTVRLELPQYTSSDSDVESPYT----LIDSLVLMPYCKSLDIFTVGGSG 722
P PVC E G +Y + L+L + T + E+PY+ LIDSLVL+P L++F SG
Sbjct: 678 PNPVCLEPGISYKLHLKLVR-TGGSAQPETPYSGPGLLIDSLVLLPRVLVLEMF----SG 732
Query: 723 DGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLS 782
TF+RY+C E KT ++ C ++ S+S L++ L C+C+PQGSLS
Sbjct: 733 GDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLS 792
Query: 783 SVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHC 842
S C+P+GGQC C+P VVGR C+ CAPG +GFGP+GC+ C+C +G++++ C +GQC C
Sbjct: 793 SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLC 852
Query: 843 FQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGY 902
G + +CDRC G WGFPSC+PC CNGHAD+C+ TG CL C+D+T G +CERC+AG+
Sbjct: 853 RTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGF 912
Query: 903 YGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGY 962
+GDP + G CRPCPCP+GP S R FA SC+QD + Q+ C C GY G RC+ CA G+
Sbjct: 913 HGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
Query: 963 FGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQ 1022
FG+PS GG CQ C+C NID DP+ACD TG+CL+CL+HTEG HC C+ G++G A +
Sbjct: 973 FGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAAR 1032
Query: 1023 QDCRKCVCNYLGTVQEHCNGSD-CQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGC 1081
Q C +C CN LGT + C D C CD ++GQC CLPNV G +CDRCAPN W L SG GC
Sbjct: 1033 QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC 1092
Query: 1082 DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIET 1141
PC C+ + + GP+CNEFTGQC C GFGGRTCSECQEL WGDP ++C ACDCD RGI+T
Sbjct: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDT 1152
Query: 1142 PQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFL 1201
PQC + TG C C GV G RCD+C RG+SG+FP C PCH CF WD ++ +L RT R
Sbjct: 1153 PQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLE 1212
Query: 1202 EKAKALKISGVIGPYRETVDSVERKVSEIKDIL-AQSPAAEPLKNIGNLFEEAEKLIKDV 1260
++A+ L+ +GV+G + + ++ K+ ++ I+ A++ +A + EE + I +
Sbjct: 1213 QRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEA 1272
Query: 1261 TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS 1320
TE + Q+E L+D ++ + L L+ + +L+ T+++L + L+ +K+S+ GA DS
Sbjct: 1273 TEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDS 1332
Query: 1321 ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE 1380
I S EAE R N S S V SA R R E +M ++ F K R L +
Sbjct: 1333 IRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGK 1392
Query: 1381 LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA 1440
L+ +L L+ E+ CG P A C+ + CGG CR ++G+ +CGG C G A A
Sbjct: 1393 LSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLA 1452
Query: 1441 WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL 1500
+A ++ ALAE + V+E + +A EA+Q A+ L K NA++ +++++N+EL
Sbjct: 1453 LGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQEL 1512
Query: 1501 RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI 1560
+ LI+ +++FL Q+ AD DSIE VA VL++ +P++ +Q+Q+L I ERV SL+ V+ I
Sbjct: 1513 QELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAI 1572
Query: 1561 LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI 1620
L + D+ RAE LL++A+RA A D K A+ V+ ALEEA++AQ A+ AI+ A D
Sbjct: 1573 LARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADT 1632
Query: 1621 QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK 1680
+ T+ L ++ A +E L +A +R +L+ +E LK K A NS A E+ + +
Sbjct: 1633 RDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQ 1692
Query: 1681 QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL 1740
A++ ++ L G L ++Y+ V+ L +K + A+ +AE L++EA+ LL A KLQ L
Sbjct: 1693 GRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRL 1752
Query: 1741 KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTC 1785
++LE YE+N+R LE KA +L LE +RS+L+ I+ +V +Y+TC
Sbjct: 1753 QELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTC 1797
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 1456 bits (3769), Expect = 0.0
Identities = 733/1785 (41%), Positives = 1037/1785 (58%), Gaps = 77/1785 (4%)
Query: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETL 89
C G+C+P TGDLL+GR +L +STCGL + + YCI+S+L+ ++KCFIC+S+ PY
Sbjct: 23 CNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYD 82
Query: 90 NPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
P+SH IENV+ +F P+R K WWQSENG+++V+I+LDLEA F F+HLI+TFKTFRPAAML
Sbjct: 83 QPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAML 142
Query: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRA 209
+ERS+D+G W V++YFA DC SFP I++G + V DI+CDS+YSDIEPST GEV+ +
Sbjct: 143 VERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKV 202
Query: 210 LDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRM-EIREKYYYAVYDMVVR 268
LDP+F+IE+PYSP IQ+L+ +TNLRI F KLHTLGD LL R + +KYYYA+Y+M+VR
Sbjct: 203 LDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVR 262
Query: 269 GNCFCYGHASECAPVDGFNEEV---EGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAE 325
G+CFC GHASEC P+ +V GMVHG C+C+HNT G NCE C DF+ D PWRPA
Sbjct: 263 GSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAA 322
Query: 326 GRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHP 385
NAC+ C+CN HS CHFDM YLA+G +SGGVC+DCQHNT G++C++C+P +Y+ P
Sbjct: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDP 382
Query: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
+ I DP C C CDP G+ + GIC S++D + G +AGQC CK NVEG CD CK Y
Sbjct: 383 LKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY 442
Query: 446 DLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLD 505
LS+ DP GC+ C CNPLG++P CD +TG C C VTG HC++C +WGL N L
Sbjct: 443 GLSATDPLGCQPCDCNPLGSLP-FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLH 501
Query: 506 GCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANL- 564
GC PCDCD+GGA +N C ++GQC CRPH+ GR C+E PGY+FA L+ YLYEAEEA
Sbjct: 502 GCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTL 561
Query: 565 -------------GPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPYSMEYD 611
P V +V + + +WTG GF RV GA L F ++NIP+ +++
Sbjct: 562 QGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNIPFPVDFT 621
Query: 612 ILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVLPRPVC 671
I I YE Q W ++ V PG S C Q +L +R ++LP P+C
Sbjct: 622 IAIHYETQSAADWTVQIV-VNPPG---GSEHCIPKTLQSKPQSFALPAATRIMLLPTPIC 677
Query: 672 FEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAW 731
E Y++ + Q +S S + L+DSL L+P SL+ F +
Sbjct: 678 LEPDVQYSIDVYFSQPLQGESHAHS-HVLVDSLGLIPQINSLENF---------CSKQDL 727
Query: 732 ETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQ 791
+ +Q + C+E + ++ + C +I S+SA LH +AC+C PQGS+ S C GGQ
Sbjct: 728 DEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQ 787
Query: 792 CQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQC 851
CQC+P VVGR C+RC+ G++ G GC PC CH QGS + C+ VTGQC C V R+C
Sbjct: 788 CQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRC 847
Query: 852 DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSG 911
DRCL G++GFPSC PC CN A+ CDP TG C NC +T G NCERC+ GYYG+P SG
Sbjct: 848 DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNP--SSG 905
Query: 912 DHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG 971
CRPC CPD P S + FA SCYQ+ + + C C GY G++C +C++G++GNP G
Sbjct: 906 QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGA 965
Query: 972 SCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCN 1031
CQPC C+NNID TDPE+C + TG CL+CL++T+G +CQ C+ G+YG AL Q CR+C C+
Sbjct: 966 PCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCH 1025
Query: 1032 YLGTVQEHC--NGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAA 1089
G C G C CD TG C CLPNV G CDRCA W L G GC C+C+
Sbjct: 1026 ASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPR 1085
Query: 1090 HSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTG 1149
S C++ TGQC C G+GG+ CSECQE ++GDP C CDC+ G + P CD TG
Sbjct: 1086 TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTG 1145
Query: 1150 QCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKI 1209
C C EGV G RCD+C RG+S FP C CH CF WD I+ L+ + A ++
Sbjct: 1146 MCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMED 1205
Query: 1210 SGVIGPYRET-VDSVERKVSEIKDILAQS--PAAEPLKNIGNLFEEAEKLIKDVTEMMAQ 1266
P E + VSEI+ IL P+ + LK +KD + + +
Sbjct: 1206 KRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLK------------VKDYHDSVRR 1253
Query: 1267 VEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEF---IKNSDIRGALDSITK 1323
++L++ D+++ D +++L E+++ + N+ I + ++I K
Sbjct: 1254 QIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKK 1313
Query: 1324 YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAG 1383
Y+ +S AE+++N E +ST+ SA R+ + ++ + + L E
Sbjct: 1314 YYHISSSAEKKIN----ETSSTINTSANTRNDLLTIL--------DTLTSKGNLSLERLK 1361
Query: 1384 KLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQK 1443
+++ D+ E CG P C CGG C +G RKC GPGC G +T++ NA QK
Sbjct: 1362 QIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQK 1421
Query: 1444 AMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNL 1503
A + + + +V L + +A+ +K +A + K + + D E +
Sbjct: 1422 AQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLF 1481
Query: 1504 IKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQH 1563
IK+++NFL +++ + IE VAN VL + +P Q L + I++ ++
Sbjct: 1482 IKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENR 1541
Query: 1564 SAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGT 1623
+ A+ LL +AK A K+A ++ + D L++A+ Q A I Q +I
Sbjct: 1542 LNEEADGAQKLLVKAKAAEKAA-NILLNLDKTLNQLQQAQITQGRANSTITQLTANITKI 1600
Query: 1624 QNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSA 1683
+ + E++T + L A QR S LE + L+ K ++ A + +SA
Sbjct: 1601 KKNVLQAENQTREMKSELELAKQR-SGLEDGLSLLQTKLQRHQDHAVNAK----VQAESA 1655
Query: 1684 EDVKKTLDGELDEKYKKVENLIAKKTEESA---DARRKAEMLQNEAKTLLAQANSKLQLL 1740
+ +L+ E E KK ++ +KT + + K + L++ A+ L +K++ +
Sbjct: 1656 QHQAGSLEKEFVE-LKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRI 1714
Query: 1741 KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTC 1785
DLERK +D + KA +L LE +V ++ +I ++ Y+ C
Sbjct: 1715 TDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARC 1759
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 424 bits (1090), Expect = e-118
Identities = 218/517 (42%), Positives = 296/517 (57%), Gaps = 30/517 (5%)
Query: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETL 89
C+ G+CYP GDLL+GR + L +STCGL KPE YC + + KC C+S+ P+
Sbjct: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
Query: 90 NPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
N SH +ENV ++ P R WWQS+N V V++QLDL+ F ++M F+ PA ML
Sbjct: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
Query: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE---GEVI 206
IERSSDFGKTW VY+Y A DC ++FP + G + D+ C S P+ G+V
Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQ--RPNARLNGGKVQ 190
Query: 207 FRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMV 266
+D I S +IQ + +ITNLR+ F +L + R YYAV +
Sbjct: 191 LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPV-----PQRGYHPPSAYYAVSQLR 245
Query: 267 VRGNCFCYGHASECAPVDGFNE--EVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPA 324
++G+CFC+GHA CAP G + VH C+C+HNT G NCE C FY++ PWRPA
Sbjct: 246 LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPA 305
Query: 325 EGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQH 384
EG++++ C++C+CN HS +CHFD AV+ A+ GGVCD+C+ +T G+NCE+C+ Y+++
Sbjct: 306 EGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
Query: 385 PERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
C C CDP G+ CD T GQC CK +V+GE CD+CK GF
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVT--------GQCVCKEHVQGERCDLCKPGF 417
Query: 445 YDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
L+ +P GC C CN LG+ PCD E+G C C V G CDQC P HW L++
Sbjct: 418 TGLTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG- 475
Query: 505 DGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCN 541
GC PC CD +L+ C +GQC CR G C+
Sbjct: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
Score = 396 bits (1017), Expect = e-109
Identities = 272/964 (28%), Positives = 461/964 (47%), Gaps = 87/964 (9%)
Query: 867 CQCNGHADDCDPVTGECLN------------CQDYTMGHNCERCLAGYYGD----PIIGS 910
C C+GHAD C P G CQ T G NCERC A +Y + P G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERC-APFYNNRPWRPAEGQ 308
Query: 911 GDH-CRPCPCPDGPDSGRQFARSCYQDPVTLQLAC-----VCD---PGYIGSRCDDCASG 961
H C+ C C + +C+ DP + VCD G C+ C
Sbjct: 309 DAHECQRCDC-------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 962 YFGNP---SEVGGSCQPCQCHNNIDTTDPEA-CDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
YF N + + +C C+C + D P A CD TG+C+ C H +GE C C+ G+
Sbjct: 362 YFRNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
Query: 1018 G--DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
G A Q C +C CN LG+ + D CD+ +G+CLCLPNV+G CD+CAP W+L
Sbjct: 419 GLTYANPQGCHRCDCNILGSRR------DMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
Query: 1076 ASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-----ECQELFWGDPDVECR 1130
ASG GC+PC C+ +S P CN+FTGQC C GFGG CS +C + +GD CR
Sbjct: 473 ASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCR 532
Query: 1131 ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVII 1190
ACDCD RG E P CD+++G+C+C G+ GPRCD+C RGY +P C CH CF +D +
Sbjct: 533 ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADL 592
Query: 1191 AELTNRTHRFLEKAKALKISGVIGPYRETVDSV---ERKVSEIKDILAQSPAA--EPLKN 1245
E R R L A A SG R + + K+ +I+ +L+ SPA + +
Sbjct: 593 REQALRFGR-LRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLS-SPAVTEQEVAQ 650
Query: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQ 1305
+ + + ++ + Q+++ L + T S ++L+SL L + EQ
Sbjct: 651 VASAILSLRRTLQGL-----QLDLPLEEETL---SLPRDLESLDRSFNGLLTMYQRKREQ 702
Query: 1306 LEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERES 1365
E I ++D GA ++ ++ S +A ++V+ S+ + D++ D E E
Sbjct: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVS-----------DSSRLLDQLRDSRREAER 751
Query: 1366 QFKEK---QEEQARLLDELAGKLQSL-DLSAAAEMTCGTPPGASCSETECGGPNCRTDEG 1421
++ + L L ++ SL DL+ CG +C+ C G C D G
Sbjct: 752 LVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG 811
Query: 1422 ERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAED 1481
CG C G++ A A+ A + + + A++++ +M+ A+ A + + SA+
Sbjct: 812 -TACGS-RCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQR 869
Query: 1482 ILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQ 1541
+ + +A++ +M++ R LI+Q+R+FLT D +I+ V+ VL + +P+ +
Sbjct: 870 LETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVL 929
Query: 1542 NLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEE 1601
+I+ L V+++L + DIARA L EA+ A A V+ + V L +
Sbjct: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQ 989
Query: 1602 AEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRK 1661
A A+ ++ ++ Q+ + ++ +E+ + + ++++ + +EEL+ +
Sbjct: 990 GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQ 1049
Query: 1662 AAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEM 1721
A Q EA +++ + A ++ + + +KY ++++ + + + R +
Sbjct: 1050 ARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELKDRLGQSSMLGEQGAR-IQS 1107
Query: 1722 LQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAV 1781
++ EA+ L + + +KD+E + + + ++ +L LE V + I+ +V
Sbjct: 1108 VKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLY 1167
Query: 1782 YSTC 1785
Y+TC
Sbjct: 1168 YATC 1171
Score = 139 bits (350), Expect = 2e-32
Identities = 81/233 (34%), Positives = 111/233 (47%), Gaps = 38/233 (16%)
Query: 764 ALLHQTGLACECDPQGSL-SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCK 819
A + +T ++CECDP G++ + CDP GQC C+ +V G C+ C PG G P GC
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
Query: 820 PCECHLQGSVNAF-CNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCNGH--- 872
C+C++ GS C+ +G+C C V +CD+C P HW S C+PC C+ H
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
Query: 873 ADDCDPVTGECLNCQDYTMGHNC-----ERCLAGYYGDPIIGSGDHCRPCPC----PDGP 923
+ C+ TG+C C++ G C +C YGD G CR C C +GP
Sbjct: 490 SPQCNQFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVATG----CRACDCDFRGTEGP 544
Query: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
+ R C+C PG G RCD C GY N V +C PC
Sbjct: 545 GCDKASGR------------CLCRPGLTGPRCDQCQRGYC-NRYPVCVACHPC 584
Score = 132 bits (332), Expect = 3e-30
Identities = 72/194 (37%), Positives = 105/194 (54%), Gaps = 14/194 (7%)
Query: 365 CQHNTMGRNCEQCKPFYYQHPERDI--RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLI 422
CQHNT G NCE+C PFY P R +D + C+RC C+ S+ + S G
Sbjct: 281 CQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQGAY 339
Query: 423 AGQC-RCKLNVEGEHCDVCKEGFY-----DLSSEDPFGCKSCACNPLGTIPGGNPCDSET 476
G C C+ + EG++C+ C+ ++ S ++ C SC C+P G +PG PCD T
Sbjct: 340 GGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET--CISCECDPDGAVPGA-PCDPVT 396
Query: 477 GHCYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCD-LGGALNNSCFAESGQCSCRPH 534
G C CK V G+ CD C P GL+ + GC CDC+ LG + C ESG+C C P+
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 535 MIGRQCNEVEPGYY 548
++G +C++ P ++
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 117 bits (293), Expect = 1e-25
Identities = 87/271 (32%), Positives = 110/271 (40%), Gaps = 51/271 (18%)
Query: 773 CECDP------QGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG------CKP 820
C DP QG+ VCD CR + G+ C RC F G C
Sbjct: 325 CHFDPAVFAASQGAYGGVCD------NCRDHTEGKNCERCQLHYFRNRRPGASIQETCIS 378
Query: 821 CECHLQGSV-NAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCN--GH 872
CEC G+V A C+PVTGQC C + V +CD C PG G C C CN G
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 873 ADD--CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFA 930
D CD +G CL C +G C++C ++ + SG C PC C D +
Sbjct: 439 RRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWK---LASGQGCEPCAC----DPHNSLS 490
Query: 931 RSCYQDPVTLQLACVCDPGYIGSRCD-----DCASGYFGNPSEVGGSCQPCQCHNNIDTT 985
C Q C C G+ G C C +G +V C+ C C + T
Sbjct: 491 PQCNQ----FTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDC--DFRGT 541
Query: 986 DPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
+ CDK +GRCL C G C C+ GY
Sbjct: 542 EGPGCDKASGRCL-CRPGLTGPRCDQCQRGY 571
Score = 77.8 bits (190), Expect = 9e-14
Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 736 RYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCR 795
R CL N V P D C + +++ Q C CDP SLS C+ GQC CR
Sbjct: 450 RCLCLPN----VVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCPCR 503
Query: 796 PNVVGRTCN-----RCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQ 850
G C+ +C T+G +GC+ C+C +G+ C+ +G+C C G+ +
Sbjct: 504 EGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPR 563
Query: 851 CDRCLPGHWG-FPSCQPC 867
CD+C G+ +P C C
Sbjct: 564 CDQCQRGYCNRYPVCVAC 581
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 424 bits (1090), Expect = e-118
Identities = 218/517 (42%), Positives = 296/517 (57%), Gaps = 30/517 (5%)
Query: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETL 89
C+ G+CYP GDLL+GR + L +STCGL KPE YC + + KC C+S+ P+
Sbjct: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
Query: 90 NPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
N SH +ENV ++ P R WWQS+N V V++QLDL+ F ++M F+ PA ML
Sbjct: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
Query: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE---GEVI 206
IERSSDFGKTW VY+Y A DC ++FP + G + D+ C S P+ G+V
Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQ--RPNARLNGGKVQ 190
Query: 207 FRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMV 266
+D I S +IQ + +ITNLR+ F +L + R YYAV +
Sbjct: 191 LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPV-----PQRGYHPPSAYYAVSQLR 245
Query: 267 VRGNCFCYGHASECAPVDGFNE--EVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPA 324
++G+CFC+GHA CAP G + VH C+C+HNT G NCE C FY++ PWRPA
Sbjct: 246 LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPA 305
Query: 325 EGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQH 384
EG++++ C++C+CN HS +CHFD AV+ A+ GGVCD+C+ +T G+NCE+C+ Y+++
Sbjct: 306 EGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
Query: 385 PERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
C C CDP G+ CD T GQC CK +V+GE CD+CK GF
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVT--------GQCVCKEHVQGERCDLCKPGF 417
Query: 445 YDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
L+ +P GC C CN LG+ PCD E+G C C V G CDQC P HW L++
Sbjct: 418 TGLTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG- 475
Query: 505 DGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCN 541
GC PC CD +L+ C +GQC CR G C+
Sbjct: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
Score = 396 bits (1017), Expect = e-109
Identities = 272/964 (28%), Positives = 461/964 (47%), Gaps = 87/964 (9%)
Query: 867 CQCNGHADDCDPVTGECLN------------CQDYTMGHNCERCLAGYYGD----PIIGS 910
C C+GHAD C P G CQ T G NCERC A +Y + P G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERC-APFYNNRPWRPAEGQ 308
Query: 911 GDH-CRPCPCPDGPDSGRQFARSCYQDPVTLQLAC-----VCD---PGYIGSRCDDCASG 961
H C+ C C + +C+ DP + VCD G C+ C
Sbjct: 309 DAHECQRCDC-------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 962 YFGNP---SEVGGSCQPCQCHNNIDTTDPEA-CDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
YF N + + +C C+C + D P A CD TG+C+ C H +GE C C+ G+
Sbjct: 362 YFRNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
Query: 1018 G--DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
G A Q C +C CN LG+ + D CD+ +G+CLCLPNV+G CD+CAP W+L
Sbjct: 419 GLTYANPQGCHRCDCNILGSRR------DMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
Query: 1076 ASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-----ECQELFWGDPDVECR 1130
ASG GC+PC C+ +S P CN+FTGQC C GFGG CS +C + +GD CR
Sbjct: 473 ASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCR 532
Query: 1131 ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVII 1190
ACDCD RG E P CD+++G+C+C G+ GPRCD+C RGY +P C CH CF +D +
Sbjct: 533 ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADL 592
Query: 1191 AELTNRTHRFLEKAKALKISGVIGPYRETVDSV---ERKVSEIKDILAQSPAA--EPLKN 1245
E R R L A A SG R + + K+ +I+ +L+ SPA + +
Sbjct: 593 REQALRFGR-LRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLS-SPAVTEQEVAQ 650
Query: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQ 1305
+ + + ++ + Q+++ L + T S ++L+SL L + EQ
Sbjct: 651 VASAILSLRRTLQGL-----QLDLPLEEETL---SLPRDLESLDRSFNGLLTMYQRKREQ 702
Query: 1306 LEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERES 1365
E I ++D GA ++ ++ S +A ++V+ S+ + D++ D E E
Sbjct: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVS-----------DSSRLLDQLRDSRREAER 751
Query: 1366 QFKEK---QEEQARLLDELAGKLQSL-DLSAAAEMTCGTPPGASCSETECGGPNCRTDEG 1421
++ + L L ++ SL DL+ CG +C+ C G C D G
Sbjct: 752 LVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG 811
Query: 1422 ERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAED 1481
CG C G++ A A+ A + + + A++++ +M+ A+ A + + SA+
Sbjct: 812 -TACGS-RCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQR 869
Query: 1482 ILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQ 1541
+ + +A++ +M++ R LI+Q+R+FLT D +I+ V+ VL + +P+ +
Sbjct: 870 LETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVL 929
Query: 1542 NLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEE 1601
+I+ L V+++L + DIARA L EA+ A A V+ + V L +
Sbjct: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQ 989
Query: 1602 AEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRK 1661
A A+ ++ ++ Q+ + ++ +E+ + + ++++ + +EEL+ +
Sbjct: 990 GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQ 1049
Query: 1662 AAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEM 1721
A Q EA +++ + A ++ + + +KY ++++ + + + R +
Sbjct: 1050 ARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELKDRLGQSSMLGEQGAR-IQS 1107
Query: 1722 LQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAV 1781
++ EA+ L + + +KD+E + + + ++ +L LE V + I+ +V
Sbjct: 1108 VKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLY 1167
Query: 1782 YSTC 1785
Y+TC
Sbjct: 1168 YATC 1171
Score = 139 bits (350), Expect = 2e-32
Identities = 81/233 (34%), Positives = 111/233 (47%), Gaps = 38/233 (16%)
Query: 764 ALLHQTGLACECDPQGSL-SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCK 819
A + +T ++CECDP G++ + CDP GQC C+ +V G C+ C PG G P GC
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
Query: 820 PCECHLQGSVNAF-CNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCNGH--- 872
C+C++ GS C+ +G+C C V +CD+C P HW S C+PC C+ H
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
Query: 873 ADDCDPVTGECLNCQDYTMGHNC-----ERCLAGYYGDPIIGSGDHCRPCPC----PDGP 923
+ C+ TG+C C++ G C +C YGD G CR C C +GP
Sbjct: 490 SPQCNQFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVATG----CRACDCDFRGTEGP 544
Query: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
+ R C+C PG G RCD C GY N V +C PC
Sbjct: 545 GCDKASGR------------CLCRPGLTGPRCDQCQRGYC-NRYPVCVACHPC 584
Score = 132 bits (332), Expect = 3e-30
Identities = 72/194 (37%), Positives = 105/194 (54%), Gaps = 14/194 (7%)
Query: 365 CQHNTMGRNCEQCKPFYYQHPERDI--RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLI 422
CQHNT G NCE+C PFY P R +D + C+RC C+ S+ + S G
Sbjct: 281 CQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQGAY 339
Query: 423 AGQC-RCKLNVEGEHCDVCKEGFY-----DLSSEDPFGCKSCACNPLGTIPGGNPCDSET 476
G C C+ + EG++C+ C+ ++ S ++ C SC C+P G +PG PCD T
Sbjct: 340 GGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET--CISCECDPDGAVPGA-PCDPVT 396
Query: 477 GHCYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCD-LGGALNNSCFAESGQCSCRPH 534
G C CK V G+ CD C P GL+ + GC CDC+ LG + C ESG+C C P+
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 535 MIGRQCNEVEPGYY 548
++G +C++ P ++
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 117 bits (293), Expect = 1e-25
Identities = 87/271 (32%), Positives = 110/271 (40%), Gaps = 51/271 (18%)
Query: 773 CECDP------QGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG------CKP 820
C DP QG+ VCD CR + G+ C RC F G C
Sbjct: 325 CHFDPAVFAASQGAYGGVCD------NCRDHTEGKNCERCQLHYFRNRRPGASIQETCIS 378
Query: 821 CECHLQGSV-NAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCN--GH 872
CEC G+V A C+PVTGQC C + V +CD C PG G C C CN G
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 873 ADD--CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFA 930
D CD +G CL C +G C++C ++ + SG C PC C D +
Sbjct: 439 RRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWK---LASGQGCEPCAC----DPHNSLS 490
Query: 931 RSCYQDPVTLQLACVCDPGYIGSRCD-----DCASGYFGNPSEVGGSCQPCQCHNNIDTT 985
C Q C C G+ G C C +G +V C+ C C + T
Sbjct: 491 PQCNQ----FTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDC--DFRGT 541
Query: 986 DPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
+ CDK +GRCL C G C C+ GY
Sbjct: 542 EGPGCDKASGRCL-CRPGLTGPRCDQCQRGY 571
Score = 77.8 bits (190), Expect = 9e-14
Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 736 RYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCR 795
R CL N V P D C + +++ Q C CDP SLS C+ GQC CR
Sbjct: 450 RCLCLPN----VVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCPCR 503
Query: 796 PNVVGRTCN-----RCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQ 850
G C+ +C T+G +GC+ C+C +G+ C+ +G+C C G+ +
Sbjct: 504 EGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPR 563
Query: 851 CDRCLPGHWG-FPSCQPC 867
CD+C G+ +P C C
Sbjct: 564 CDQCQRGYCNRYPVCVAC 581
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 424 bits (1090), Expect = e-118
Identities = 218/517 (42%), Positives = 296/517 (57%), Gaps = 30/517 (5%)
Query: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETL 89
C+ G+CYP GDLL+GR + L +STCGL KPE YC + + KC C+S+ P+
Sbjct: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
Query: 90 NPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
N SH +ENV ++ P R WWQS+N V V++QLDL+ F ++M F+ PA ML
Sbjct: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
Query: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE---GEVI 206
IERSSDFGKTW VY+Y A DC ++FP + G + D+ C S P+ G+V
Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQ--RPNARLNGGKVQ 190
Query: 207 FRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMV 266
+D I S +IQ + +ITNLR+ F +L + R YYAV +
Sbjct: 191 LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPV-----PQRGYHPPSAYYAVSQLR 245
Query: 267 VRGNCFCYGHASECAPVDGFNE--EVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPA 324
++G+CFC+GHA CAP G + VH C+C+HNT G NCE C FY++ PWRPA
Sbjct: 246 LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPA 305
Query: 325 EGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQH 384
EG++++ C++C+CN HS +CHFD AV+ A+ GGVCD+C+ +T G+NCE+C+ Y+++
Sbjct: 306 EGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
Query: 385 PERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
C C CDP G+ CD T GQC CK +V+GE CD+CK GF
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVT--------GQCVCKEHVQGERCDLCKPGF 417
Query: 445 YDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
L+ +P GC C CN LG+ PCD E+G C C V G CDQC P HW L++
Sbjct: 418 TGLTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG- 475
Query: 505 DGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCN 541
GC PC CD +L+ C +GQC CR G C+
Sbjct: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
Score = 396 bits (1017), Expect = e-109
Identities = 272/964 (28%), Positives = 461/964 (47%), Gaps = 87/964 (9%)
Query: 867 CQCNGHADDCDPVTGECLN------------CQDYTMGHNCERCLAGYYGD----PIIGS 910
C C+GHAD C P G CQ T G NCERC A +Y + P G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERC-APFYNNRPWRPAEGQ 308
Query: 911 GDH-CRPCPCPDGPDSGRQFARSCYQDPVTLQLAC-----VCD---PGYIGSRCDDCASG 961
H C+ C C + +C+ DP + VCD G C+ C
Sbjct: 309 DAHECQRCDC-------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 962 YFGNP---SEVGGSCQPCQCHNNIDTTDPEA-CDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
YF N + + +C C+C + D P A CD TG+C+ C H +GE C C+ G+
Sbjct: 362 YFRNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
Query: 1018 G--DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
G A Q C +C CN LG+ + D CD+ +G+CLCLPNV+G CD+CAP W+L
Sbjct: 419 GLTYANPQGCHRCDCNILGSRR------DMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
Query: 1076 ASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-----ECQELFWGDPDVECR 1130
ASG GC+PC C+ +S P CN+FTGQC C GFGG CS +C + +GD CR
Sbjct: 473 ASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCR 532
Query: 1131 ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVII 1190
ACDCD RG E P CD+++G+C+C G+ GPRCD+C RGY +P C CH CF +D +
Sbjct: 533 ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADL 592
Query: 1191 AELTNRTHRFLEKAKALKISGVIGPYRETVDSV---ERKVSEIKDILAQSPAA--EPLKN 1245
E R R L A A SG R + + K+ +I+ +L+ SPA + +
Sbjct: 593 REQALRFGR-LRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLS-SPAVTEQEVAQ 650
Query: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQ 1305
+ + + ++ + Q+++ L + T S ++L+SL L + EQ
Sbjct: 651 VASAILSLRRTLQGL-----QLDLPLEEETL---SLPRDLESLDRSFNGLLTMYQRKREQ 702
Query: 1306 LEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERES 1365
E I ++D GA ++ ++ S +A ++V+ S+ + D++ D E E
Sbjct: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVS-----------DSSRLLDQLRDSRREAER 751
Query: 1366 QFKEK---QEEQARLLDELAGKLQSL-DLSAAAEMTCGTPPGASCSETECGGPNCRTDEG 1421
++ + L L ++ SL DL+ CG +C+ C G C D G
Sbjct: 752 LVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG 811
Query: 1422 ERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAED 1481
CG C G++ A A+ A + + + A++++ +M+ A+ A + + SA+
Sbjct: 812 -TACGS-RCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQR 869
Query: 1482 ILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQ 1541
+ + +A++ +M++ R LI+Q+R+FLT D +I+ V+ VL + +P+ +
Sbjct: 870 LETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVL 929
Query: 1542 NLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEE 1601
+I+ L V+++L + DIARA L EA+ A A V+ + V L +
Sbjct: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQ 989
Query: 1602 AEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRK 1661
A A+ ++ ++ Q+ + ++ +E+ + + ++++ + +EEL+ +
Sbjct: 990 GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQ 1049
Query: 1662 AAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEM 1721
A Q EA +++ + A ++ + + +KY ++++ + + + R +
Sbjct: 1050 ARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELKDRLGQSSMLGEQGAR-IQS 1107
Query: 1722 LQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAV 1781
++ EA+ L + + +KD+E + + + ++ +L LE V + I+ +V
Sbjct: 1108 VKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLY 1167
Query: 1782 YSTC 1785
Y+TC
Sbjct: 1168 YATC 1171
Score = 139 bits (350), Expect = 2e-32
Identities = 81/233 (34%), Positives = 111/233 (47%), Gaps = 38/233 (16%)
Query: 764 ALLHQTGLACECDPQGSL-SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCK 819
A + +T ++CECDP G++ + CDP GQC C+ +V G C+ C PG G P GC
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
Query: 820 PCECHLQGSVNAF-CNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCNGH--- 872
C+C++ GS C+ +G+C C V +CD+C P HW S C+PC C+ H
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
Query: 873 ADDCDPVTGECLNCQDYTMGHNC-----ERCLAGYYGDPIIGSGDHCRPCPC----PDGP 923
+ C+ TG+C C++ G C +C YGD G CR C C +GP
Sbjct: 490 SPQCNQFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVATG----CRACDCDFRGTEGP 544
Query: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
+ R C+C PG G RCD C GY N V +C PC
Sbjct: 545 GCDKASGR------------CLCRPGLTGPRCDQCQRGYC-NRYPVCVACHPC 584
Score = 132 bits (332), Expect = 3e-30
Identities = 72/194 (37%), Positives = 105/194 (54%), Gaps = 14/194 (7%)
Query: 365 CQHNTMGRNCEQCKPFYYQHPERDI--RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLI 422
CQHNT G NCE+C PFY P R +D + C+RC C+ S+ + S G
Sbjct: 281 CQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQGAY 339
Query: 423 AGQC-RCKLNVEGEHCDVCKEGFY-----DLSSEDPFGCKSCACNPLGTIPGGNPCDSET 476
G C C+ + EG++C+ C+ ++ S ++ C SC C+P G +PG PCD T
Sbjct: 340 GGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET--CISCECDPDGAVPGA-PCDPVT 396
Query: 477 GHCYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCD-LGGALNNSCFAESGQCSCRPH 534
G C CK V G+ CD C P GL+ + GC CDC+ LG + C ESG+C C P+
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 535 MIGRQCNEVEPGYY 548
++G +C++ P ++
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 117 bits (293), Expect = 1e-25
Identities = 87/271 (32%), Positives = 110/271 (40%), Gaps = 51/271 (18%)
Query: 773 CECDP------QGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG------CKP 820
C DP QG+ VCD CR + G+ C RC F G C
Sbjct: 325 CHFDPAVFAASQGAYGGVCD------NCRDHTEGKNCERCQLHYFRNRRPGASIQETCIS 378
Query: 821 CECHLQGSV-NAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCN--GH 872
CEC G+V A C+PVTGQC C + V +CD C PG G C C CN G
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 873 ADD--CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFA 930
D CD +G CL C +G C++C ++ + SG C PC C D +
Sbjct: 439 RRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWK---LASGQGCEPCAC----DPHNSLS 490
Query: 931 RSCYQDPVTLQLACVCDPGYIGSRCD-----DCASGYFGNPSEVGGSCQPCQCHNNIDTT 985
C Q C C G+ G C C +G +V C+ C C + T
Sbjct: 491 PQCNQ----FTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDC--DFRGT 541
Query: 986 DPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
+ CDK +GRCL C G C C+ GY
Sbjct: 542 EGPGCDKASGRCL-CRPGLTGPRCDQCQRGY 571
Score = 77.8 bits (190), Expect = 9e-14
Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 736 RYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCR 795
R CL N V P D C + +++ Q C CDP SLS C+ GQC CR
Sbjct: 450 RCLCLPN----VVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCPCR 503
Query: 796 PNVVGRTCN-----RCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQ 850
G C+ +C T+G +GC+ C+C +G+ C+ +G+C C G+ +
Sbjct: 504 EGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPR 563
Query: 851 CDRCLPGHWG-FPSCQPC 867
CD+C G+ +P C C
Sbjct: 564 CDQCQRGYCNRYPVCVAC 581
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 366 bits (940), Expect = e-101
Identities = 203/524 (38%), Positives = 281/524 (53%), Gaps = 58/524 (11%)
Query: 32 EGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQE----DKKCFICNSQDPYHE 87
E +C P G+L +GR KL +TCG + E YC S + KC CN+ P+
Sbjct: 31 EKACNPRMGNLALGR--KLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPH-- 86
Query: 88 TLNPDSHLIENVVTTFAPNRLKI---WWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFR 144
+ ++ + A + + WWQS V IQLDLEAEF+FTHLI+ FK+ R
Sbjct: 87 --------LAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPR 138
Query: 145 PAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGE 204
PAAM+++RS DFGKTW Y+YFA +C A+F G+ +KK IC S+YS P T GE
Sbjct: 139 PAAMVLDRSQDFGKTWKPYKYFATNCSATF-GLEDDVVKK--GAICTSKYSSPFPCTGGE 195
Query: 205 VIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYD 264
VIF+AL P + E+PYS ++Q LKITNLR++ +K + D E + +YA+YD
Sbjct: 196 VIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYD 255
Query: 265 MVVRGNCFCYGHASECAPVDGFNE-EVEG---MVHGHCMCRHNTKGLNCELCMDFYHDLP 320
+V+G+CFC GHA +C PV GF + G MVHG CMC+HNT G +C+ C Y+D P
Sbjct: 256 FIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRP 315
Query: 321 WRPAEGRNS--NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCK 378
W A+G+ N C+ C CN H+ +CHFD+ V+ A+GN SGGVCDDCQHNT G+ C++CK
Sbjct: 316 WEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCK 375
Query: 379 PFYYQHPERDIRDPNFCERCTCDPAGS-----QNEGICDSYTDFSTGLIAGQCRCKLNVE 433
P +Y+ R P+ C+ C+C P GS + CD G C CK V
Sbjct: 376 PGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSN--------GDCPCKPGVA 427
Query: 434 GEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQC 493
G CD C G++ +GC+ C C CD TG C + +
Sbjct: 428 GRRCDRCMVGYWGFGD---YGCRPCDC--------AGSCDPITGDCISSHTDIDWYHE-- 474
Query: 494 LPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
+P+ + N + + A S SG+C C+ +G
Sbjct: 475 VPDFRPVHNKSEPA----WEWEDAQGFSALLHSGKCECKEQTLG 514
Score = 101 bits (252), Expect = 6e-21
Identities = 48/113 (42%), Positives = 61/113 (53%), Gaps = 18/113 (15%)
Query: 788 NGGQCQ-CRPNVVGRTCNRCAPGTFG------FGPSGCKPCECHLQGSVN------AFCN 834
+GG C C+ N G+ C RC PG + P CKPC CH GS FC+
Sbjct: 355 SGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCD 414
Query: 835 PVTGQCHCFQGVYARQCDRCLPGHWGFP--SCQPCQCNGHADDCDPVTGECLN 885
P G C C GV R+CDRC+ G+WGF C+PC C G CDP+TG+C++
Sbjct: 415 PSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG---SCDPITGDCIS 464
Score = 100 bits (248), Expect = 2e-20
Identities = 71/258 (27%), Positives = 96/258 (37%), Gaps = 78/258 (30%)
Query: 867 CQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSG 926
C CNGHAD C PV G RP P
Sbjct: 262 CFCNGHADQCIPVHG--------------------------------FRPVKAPG----- 284
Query: 927 RQFARSCYQDPVTLQLA---CVCDPGYIGSRCDDCASGYFGNPSEVG-------GSCQPC 976
T + C+C GS C CA Y P E C+ C
Sbjct: 285 ------------TFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTC 332
Query: 977 QCHNNIDTTDPE------ACDKETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQDC 1025
+C+ + DT + + ++ G C C ++TEG++CQ C+ G+Y D + C
Sbjct: 333 KCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDAC 392
Query: 1026 RKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCN 1085
+ C C+ +G+ N S CD + G C C P V G+ CDRC W GC PC+
Sbjct: 393 KPCSCHPVGSAVLPAN-SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD-YGCRPCD 450
Query: 1086 CNAAHSFGPSCNEFTGQC 1103
C SC+ TG C
Sbjct: 451 C------AGSCDPITGDC 462
Score = 93.2 bits (230), Expect = 2e-18
Identities = 57/181 (31%), Positives = 75/181 (41%), Gaps = 31/181 (17%)
Query: 995 GRCLKCLYHTEGEHCQFCRFGYYGD----------ALQQDCRKCVCN-YLGTVQEHCNGS 1043
G+C+ C ++T G HCQ C Y D +CR C CN + T N
Sbjct: 291 GKCM-CKHNTAGSHCQHCA-PLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348
Query: 1044 DCQCDKATGQCL-CLPNVIGQNCDRCAPNTWQ-----LASGTGCDPCNCNAAHSFGPSCN 1097
+ +++ G C C N GQ C RC P ++ ++ C PC+C+ S N
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 1098 EFT------GQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQC 1151
T G C C PG GR C C +WG D CR CDC CD TG C
Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC------AGSCDPITGDC 462
Query: 1152 V 1152
+
Sbjct: 463 I 463
Score = 92.0 bits (227), Expect = 5e-18
Identities = 61/195 (31%), Positives = 78/195 (40%), Gaps = 40/195 (20%)
Query: 836 VTGQCHCFQGVYARQCDRCLP-----------GHWGFPS-CQPCQCNGHADDC------- 876
V G+C C C C P G G P+ C+ C+CNGHAD C
Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348
Query: 877 ----DPVTGECLNCQDYTMGHNCERCLAGYYGD--PIIGSGDHCRPCPCPDGPDSGRQFA 930
+ G C +CQ T G C+RC G+Y D + D C+PC C +
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 931 RSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEAC 990
+ DP C C PG G RCD C GY+G C+PC C +C
Sbjct: 409 SVTFCDPSNGD--CPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDCAG--------SC 455
Query: 991 DKETGRCLKCLYHTE 1005
D TG C+ HT+
Sbjct: 456 DPITGDCISS--HTD 468
Score = 81.3 bits (199), Expect = 8e-15
Identities = 56/161 (34%), Positives = 67/161 (41%), Gaps = 35/161 (21%)
Query: 1052 GQCLCLPNVIGQNCDRCAP----NTWQLASG-TG----CDPCNCNA--------AHSFGP 1094
G+C+C N G +C CAP W+ A G TG C C CN + +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 1095 SCNEFTGQCQ-CMPGFGGRTCSECQELFWGD-------PDVECRACDCDPRGI------E 1140
S N G C C G+ C C+ F+ D PD C+ C C P G
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA-CKPCSCHPVGSAVLPANS 409
Query: 1141 TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD--CTPC 1179
CD S G C C GV G RCD+C GY G F D C PC
Sbjct: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG-FGDYGCRPC 449
Score = 76.6 bits (187), Expect = 2e-13
Identities = 34/74 (45%), Positives = 43/74 (58%), Gaps = 12/74 (16%)
Query: 773 CECDPQGSLS------SVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
C C P GS + CDP+ G C C+P V GR C+RC G +GFG GC+PC+C
Sbjct: 395 CSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--A 452
Query: 827 GSVNAFCNPVTGQC 840
GS C+P+TG C
Sbjct: 453 GS----CDPITGDC 462
Score = 76.3 bits (186), Expect = 3e-13
Identities = 63/213 (29%), Positives = 82/213 (38%), Gaps = 62/213 (29%)
Query: 770 GLACECDPQGSLSSVCDPNG-----GQCQCRPNVVGRTCNRCAP-----------GTFGF 813
G A +C P V P G+C C+ N G C CAP G G
Sbjct: 266 GHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTG- 324
Query: 814 GPSGCKPCE-------CHLQGSV-NAFCNPVTGQC-HCFQGVYARQCDRCLPGHW----- 859
P+ C+ C+ CH +V A N G C C + C RC PG +
Sbjct: 325 APNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRR 384
Query: 860 ---GFPSCQPCQCN---------GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPI 907
+C+PC C+ CDP G+C C+ G C+RC+ GY+
Sbjct: 385 PFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYW---- 439
Query: 908 IGSGDH-CRPCPCPDGPDSGRQFARSCYQDPVT 939
G GD+ CRPC C A SC DP+T
Sbjct: 440 -GFGDYGCRPCDC----------AGSC--DPIT 459
Score = 68.2 bits (165), Expect = 7e-11
Identities = 49/162 (30%), Positives = 67/162 (41%), Gaps = 44/162 (27%)
Query: 421 LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-------CKSCACN------------ 461
++ G+C CK N G HC C + D E G C++C CN
Sbjct: 288 MVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNV 347
Query: 462 --PLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL-------DGCRPCDC 512
G GG CD C+ GQ+C +C P G DL D C+PC C
Sbjct: 348 WEASGNRSGG-VCDD------CQHNTEGQYCQRCKP---GFYRDLRRPFSAPDACKPCSC 397
Query: 513 D-LGGAL--NNS---CFAESGQCSCRPHMIGRQCNEVEPGYY 548
+G A+ NS C +G C C+P + GR+C+ GY+
Sbjct: 398 HPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 340 bits (872), Expect = 7e-93
Identities = 255/987 (25%), Positives = 433/987 (43%), Gaps = 144/987 (14%)
Query: 840 CHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMG 892
C C G + C+ CL G+ + C C CNGH++ CDP TG C NC+D T G
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC-NCRDNTAG 748
Query: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-CDPGYI 951
+CE+C GYYGD G+ C+PCPCP G SC P T ++ C C G
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPGGS--------SCAVVPKTKEVVCTNCPTGTT 800
Query: 952 GSRCDDCASGYFGNPSEVGGS---CQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
G RC+ C GYFG+P G C+ CQC +NID C++ TG CLKC+Y+T G +
Sbjct: 801 GKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFY 860
Query: 1009 CQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQN 1064
C C+ G++G+ L + C+ C CN GT+++ + C+ TGQC CLP+V GQ+
Sbjct: 861 CDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSS-----CNPVTGQCECLPHVTGQD 915
Query: 1065 CDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD 1124
C C P + L SG GC+ C+C+A S C+ TGQC+C PG G+ C C+ +G
Sbjct: 916 CGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGF 975
Query: 1125 PDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRG--YSGVFPDCTPCHQC 1182
C+ CDC P G + QC + G+C C EG G RCD+C Y+ +P C C C
Sbjct: 976 GPEGCKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPAC 1034
Query: 1183 FALWDVIIAELTNRTHRF-LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAE 1241
+ L +A+ HR L++ ++L + G T + E ++ E +
Sbjct: 1035 YRLVKDKVAD-----HRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAE---------- 1079
Query: 1242 PLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKE 1301
+ + +L EA+ +KDV + L D + N+T L S + +++ NT++E
Sbjct: 1080 --REVMDLLREAQD-VKDVDQ-------NLMDRLQRVNNT---LSSQISRLQNIRNTIEE 1126
Query: 1302 LAEQLEFIKNSDIRGALDSITKYFQMSLEAEER-----VNASTTEPNSTVEQSALMRDRV 1356
E R +++ + +++ E+ N S T+P ST + + +
Sbjct: 1127 TGNLAE-----QARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNM----- 1176
Query: 1357 EDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNC 1416
++ E + E+ +++A D++ ++ A+ + TE
Sbjct: 1177 -TLLAEEARKLAERHKQEA---DDIVRVAKT----------------ANDTSTEAYNLLL 1216
Query: 1417 RTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAK 1476
RT GE + + + +++A ++ QD+ A V + EAK D+A
Sbjct: 1217 RTLAGENQTAFE-----IEELNRKYEQAKNISQDLEKQAARVHE------EAKRAGDKAV 1265
Query: 1477 QSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPST 1536
+ + + E ++ ++ + + + Q D E L+ +M
Sbjct: 1266 EIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDY--------EDLREDMRGK 1317
Query: 1537 PQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEM------LLEEAKRASKSATDVKV 1590
+++NL E + + E + +++ + AA E L+EA + D
Sbjct: 1318 ELEVKNLLE--KGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDR 1375
Query: 1591 TADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISE 1650
+ K A EEA + A + I +A+E + Q L S ++ ++ A + S
Sbjct: 1376 RVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASA 1435
Query: 1651 LERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTE 1710
+++N K +A + E ++ V + + ++ +K L + D+ + + + ++
Sbjct: 1436 VQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDM-MMAGMASQ 1494
Query: 1711 ESADARRKAEMLQNEAKTLLAQANSKLQLLKDL--------------------ERKYEDN 1750
+ +A A +N +LL+ N L+ L L E K D
Sbjct: 1495 AAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDL 1554
Query: 1751 QRYLEDKAQELARLEGEVRSLLKDISQ 1777
R + D E + E + +DI +
Sbjct: 1555 DRKVSDLENEAKKQEAAIMDYNRDIEE 1581
Score = 271 bits (693), Expect = 4e-72
Identities = 159/476 (33%), Positives = 249/476 (52%), Gaps = 60/476 (12%)
Query: 53 TSTCGLHKPEPYCIVSHLQE-DKKCFICNSQDPYHETLNPDSHLIENV--VTTFAPNRLK 109
T+TCG PE YC+ + + K C +C++ P HL +T +
Sbjct: 66 TNTCGT-PPEEYCVQTGVTGVTKSCHLCDAGQP---------HLQHGAAFLTDYNNQADT 115
Query: 110 IWWQSEN---GVE---NVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVY 163
WWQS+ GV+ ++ + L L F T++ + F T RP + I + + W Y
Sbjct: 116 TWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPY 175
Query: 164 RYFAYDCEASFPGISTGPMKKVDD---IICDSRYSDIEPSTEGEVIFRALD---PAFKIE 217
+Y++ CE ++ + G ++ D +C +SDI P T G V F L+ A+ +
Sbjct: 176 QYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFD 235
Query: 218 DPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHA 277
+ SP +Q + T++R+ +L+T GD + + ++ + YYYA+ D V G C C GHA
Sbjct: 236 N--SPVLQEWVTATDIRVTLNRLNTFGDEVFNDP-KVLKSYYYAISDFAVGGRCKCNGHA 292
Query: 278 SECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNC 337
SEC E + +V C C+HNT G++CE C+ F++D PWR A +++ C C+C
Sbjct: 293 SEC-----MKNEFDKLV---CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC 344
Query: 338 NEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCER 397
N S C+FD +Y +TG+ GG C +CQ NT G +CE+C+ +++ + + C
Sbjct: 345 NGRSQECYFDPELYRSTGH--GGHCTNCQDNTDGAHCERCRENFFR-----LGNNEACSS 397
Query: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
C C P GS + CDSY G+C CK V G+ CD C+ GF+ L+ GC+
Sbjct: 398 CHCSPVGSLSTQ-CDSY---------GRCSCKPGVMGDKCDRCQPGFHSLTEA---GCRP 444
Query: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDC 512
C+C+P G+I + C+ ETG C CK V G +C++C P + L S++ GC PC C
Sbjct: 445 CSCDPSGSI---DECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 168 bits (425), Expect = 5e-41
Identities = 105/333 (31%), Positives = 155/333 (46%), Gaps = 46/333 (13%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG----CKPCECHLQGS 828
C C+ S CDP G C CR N G C +C+ G +G +G C+PC C G
Sbjct: 724 CACNGH---SETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPC--PGG 778
Query: 829 VNAFCNPVTGQ---CHCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNGHAD--- 874
+ P T + +C G ++C+ C G++G P C+ CQC+ + D
Sbjct: 779 SSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNA 838
Query: 875 --DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPCPDGPDSGRQFAR 931
+C+ +TGECL C T G C+RC G++G+P+ D C+ C C +Q
Sbjct: 839 VGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ--S 896
Query: 932 SCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACD 991
SC +PVT Q C C P G C C G++ S G C+ C CH + +T+ + CD
Sbjct: 897 SC--NPVTGQ--CECLPHVTGQDCGACDPGFYNLQS--GQGCERCDCH-ALGSTNGQ-CD 948
Query: 992 KETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKAT 1051
TG+C +C G+HC+ C ++G + C+ C C+ G++ C K
Sbjct: 949 IRTGQC-ECQPGITGQHCERCEVNHFGFG-PEGCKPCDCHPEGSLSLQC--------KDD 998
Query: 1052 GQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPC 1084
G+C C +G CD+C N + S GC C
Sbjct: 999 GRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 157 bits (397), Expect = 9e-38
Identities = 116/382 (30%), Positives = 156/382 (40%), Gaps = 102/382 (26%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSN 330
C C GH+ C P G C CR NT G +CE C D Y+ + S+
Sbjct: 724 CACNGHSETCDPETGV-----------CNCRDNTAGPHCEKCSDGYYG----DSTAGTSS 768
Query: 331 ACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE---- 386
C+ C C S SC AV T V VC +C T G+ CE C Y+ P
Sbjct: 769 DCQPCPCPGGS-SC----AVVPKTKEV---VCTNCPTGTTGKRCELCDDGYFGDPLGRNG 820
Query: 387 ----------RDIRDPN----------------------FCERC---------TCDPAGS 405
D DPN +C+RC +PA
Sbjct: 821 PVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADK 880
Query: 406 QNEGICDSYTDF----STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACN 461
C+ Y S + GQC C +V G+ C C GFY+L S GC+ C C+
Sbjct: 881 CKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQ--GCERCDCH 938
Query: 462 PLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNS 521
LG+ G CD TG C C+ +TGQHC++C H+G +GC+PCDC G+L+
Sbjct: 939 ALGSTNG--QCDIRTGQCECQPGITGQHCERCEVNHFGFGP--EGCKPCDCHPEGSLSLQ 994
Query: 522 CFAESGQCSCRPHMIGRQCNEVEPGYYF-------------------ATLDH--YLYEAE 560
C + G+C CR +G +C++ E Y++ DH L E E
Sbjct: 995 C-KDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELE 1053
Query: 561 E--ANLGPGVSIVERQYIQDRI 580
ANLG G +V Q +DR+
Sbjct: 1054 SLIANLGTGDEMVTDQAFEDRL 1075
Score = 136 bits (342), Expect = 2e-31
Identities = 77/219 (35%), Positives = 109/219 (49%), Gaps = 25/219 (11%)
Query: 334 KCNCNEHSISC---HFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIR 390
+C CN H+ C FD V +C+HNT G +CE+C PF+ P R
Sbjct: 285 RCKCNGHASECMKNEFDKLVC------------NCKHNTYGVDCEKCLPFFNDRPWRRAT 332
Query: 391 DPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSS 449
+ E CD G E D STG G C C+ N +G HC+ C+E F+ L +
Sbjct: 333 AESASECLPCDCNGRSQECYFDPELYRSTGH-GGHCTNCQDNTDGAHCERCRENFFRLGN 391
Query: 450 EDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRP 509
+ C SC C+P+G++ CDS G C CK V G CD+C P L+ GCRP
Sbjct: 392 NE--ACSSCHCSPVGSL--STQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEA--GCRP 444
Query: 510 CDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
C CD G+++ C E+G+C C+ ++ G C +PG++
Sbjct: 445 CSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKPGFF 482
Score = 125 bits (315), Expect = 3e-28
Identities = 85/296 (28%), Positives = 113/296 (38%), Gaps = 57/296 (19%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C C G CE+C+ Y P G S C C CN HS +C + V N
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRET--PNLGPYS-PCVLCACNGHSETCDPETGVCNCRDNT 746
Query: 358 SGG-----------------------------------------VCDDCQHNTMGRNCEQ 376
+G VC +C T G+ CE
Sbjct: 747 AGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCEL 806
Query: 377 CKPFYYQHPERDIRDPNFCERCTC-DPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEG 434
C Y+ P C C C D G C+ T G+C +C N G
Sbjct: 807 CDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLT--------GECLKCIYNTAG 858
Query: 435 EHCDVCKEGFY--DLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ 492
+CD CK+GF+ L+ CK+C CN GT+ + C+ TG C C VTGQ C
Sbjct: 859 FYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGA 918
Query: 493 CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
C P + L + GC CDC G+ N C +GQC C+P + G+ C E ++
Sbjct: 919 CDPGFYNLQSG-QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Score = 112 bits (279), Expect = 4e-24
Identities = 73/231 (31%), Positives = 104/231 (45%), Gaps = 30/231 (12%)
Query: 969 VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-------- 1020
VGG C+ C+ + DK C ++T G C+ C ++ D
Sbjct: 282 VGGRCK---CNGHASECMKNEFDKLV---CNCKHNTYGVDCEKC-LPFFNDRPWRRATAE 334
Query: 1021 LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQ---CL-CLPNVIGQNCDRCAPNTWQLA 1076
+C C CN G QE C D + ++TG C C N G +C+RC N ++L
Sbjct: 335 SASECLPCDCN--GRSQE-CY-FDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLG 390
Query: 1077 SGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDP 1136
+ C C+C+ S C+ + G+C C PG G C CQ F + CR C CDP
Sbjct: 391 NNEACSSCHCSPVGSLSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDP 449
Query: 1137 RGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD----CTPCHQCF 1183
G +C+ TG+CVC + VEG C++C G+ + CTPC CF
Sbjct: 450 SG-SIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCF-CF 498
Score = 111 bits (277), Expect = 7e-24
Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 13/155 (8%)
Query: 772 ACECDPQGSLS--SVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF-GPSGCKPCECHLQGS 828
AC C+ G++ S C+P GQC+C P+V G+ C C PG + GC+ C+CH GS
Sbjct: 883 ACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGS 942
Query: 829 VNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF--PSCQPCQCNGHAD---DCDPVTGEC 883
N C+ TGQC C G+ + C+RC H+GF C+PC C+ C G C
Sbjct: 943 TNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKD-DGRC 1001
Query: 884 LNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCP 918
C++ +G+ C++C Y+ + S C+ CP
Sbjct: 1002 -ECREGFVGNRCDQCEENYFYN---RSWPGCQECP 1032
Score = 107 bits (266), Expect = 1e-22
Identities = 76/238 (31%), Positives = 106/238 (44%), Gaps = 44/238 (18%)
Query: 867 CQCNGHADDCDPVTGECL--NCQDYTMGHNCERCLAGYYGDP----IIGSGDHCRPCPCP 920
C+CNGHA +C + L NC+ T G +CE+CL + P S C PC C
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC- 344
Query: 921 DGPDSGRQFARSCYQDPVTLQLA-----CV-CDPGYIGSRCDDCASGYF--GNPSEVGGS 972
+GR ++ CY DP + C C G+ C+ C +F GN +
Sbjct: 345 ----NGR--SQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEA 394
Query: 973 CQPCQCH--NNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVC 1030
C C C ++ T CD GRC C G+ C C+ G++ + CR C C
Sbjct: 395 CSSCHCSPVGSLST----QCD-SYGRC-SCKPGVMGDKCDRCQPGFH-SLTEAGCRPCSC 447
Query: 1031 NYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGT--GCDPCNC 1086
+ G++ E C+ TG+C+C NV G NC+RC P + L S GC PC C
Sbjct: 448 DPSGSIDE--------CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 106 bits (264), Expect = 2e-22
Identities = 66/212 (31%), Positives = 94/212 (44%), Gaps = 40/212 (18%)
Query: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDC--DPVT------- 880
C+C Y C++CLP P C PC CNG + +C DP
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364
Query: 881 GECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTL 940
G C NCQD T G +CERC ++ +G+ + C C C P Y
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFR---LGNNEACSSCHC--SPVGSLSTQCDSYG----- 414
Query: 941 QLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKC 1000
C C PG +G +CD C G F + +E G C+PC C + + C+ ETGRC+ C
Sbjct: 415 --RCSCKPGVMGDKCDRCQPG-FHSLTEAG--CRPCSCD---PSGSIDECNIETGRCV-C 465
Query: 1001 LYHTEGEHCQFCRFGYYG--DALQQDCRKCVC 1030
+ EG +C+ C+ G++ + + C C C
Sbjct: 466 KDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 105 bits (262), Expect = 4e-22
Identities = 51/132 (38%), Positives = 69/132 (52%), Gaps = 9/132 (6%)
Query: 755 CRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFG 814
CR F + ++ +C C P GSLS+ CD + G+C C+P V+G C+RC PG
Sbjct: 382 CRENFFRLGN--NEACSSCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLT 438
Query: 815 PSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQC 869
+GC+PC C GS++ CN TG+C C V C+RC PG + S C PC C
Sbjct: 439 EAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Query: 870 NGHADDCDPVTG 881
GH+ C G
Sbjct: 498 FGHSSVCTNAVG 509
Score = 71.6 bits (174), Expect = 6e-12
Identities = 41/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%)
Query: 426 CRCKLNVEGEHCDVCKEGFYD-----LSSEDPFGCKSCACNPLGTIPGGNP----CDSET 476
C CK N G C+ C F D ++E C C CN +P
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364
Query: 477 GHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
GHC C+ G HC++C + L N+ + C C C G+L+ C + G+CSC+P +
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFRLGNN-EACSSCHCSPVGSLSTQCDSY-GRCSCKPGV 422
Query: 536 IGRQCNEVEPGYYFAT 551
+G +C+ +PG++ T
Sbjct: 423 MGDKCDRCQPGFHSLT 438
Score = 70.1 bits (170), Expect = 2e-11
Identities = 56/219 (25%), Positives = 78/219 (35%), Gaps = 73/219 (33%)
Query: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGP---------SGCKP 820
G C+C+ S + + C C+ N G C +C P F P S C P
Sbjct: 283 GGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLP-FFNDRPWRRATAESASECLP 341
Query: 821 CEC----------------------------------------------HLQGSVNAFCN 834
C+C + + + C+
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCS 401
Query: 835 PV---------TGQCHCFQGVYARQCDRCLPGHWGF--PSCQPCQC--NGHADDCDPVTG 881
PV G+C C GV +CDRC PG C+PC C +G D+C+ TG
Sbjct: 402 PVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETG 461
Query: 882 ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDH-CRPCPC 919
C+ C+D G NCERC G++ + S C PC C
Sbjct: 462 RCV-CKDNVEGFNCERCKPGFFN--LESSNPRGCTPCFC 497
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 307 bits (786), Expect = 7e-83
Identities = 254/995 (25%), Positives = 413/995 (41%), Gaps = 170/995 (17%)
Query: 840 CHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMG 892
C C G + C+ C PG+ + SC PC CN H CDP TG C+ C +T G
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEG 730
Query: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-CDPGYI 951
+CERCL G+YG+P G D C+PCPCP +C P + ++ C C PG
Sbjct: 731 PSCERCLPGFYGNPFAGQADDCQPCPCPG--------QSACTTIPESREVVCTHCPPGQR 782
Query: 952 GSRCDDCASGYFGNPSEVGGSCQPC---QCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
G RC+ C G+FG+P + G QPC QC N+D CD +G CL+CL++T G+H
Sbjct: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
Query: 1009 CQFCRFGYYGDALQ----QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQN 1064
C+ C+ G+YG AL C C C+ G+V E CD TGQC CLP+V ++
Sbjct: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM-----PCDPVTGQCSCLPHVTARD 897
Query: 1065 CDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD 1124
C RC P + L G GC C C+ S C+ TGQC C PG G+ C CQ F+G
Sbjct: 898 CSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGF 957
Query: 1125 PDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY--SGVFPDCTPCHQC 1182
CRAC C P G + QC ++ G CVC G EG +CD+C + + C C C
Sbjct: 958 SIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1016
Query: 1183 FAL-----------------W-------------DVIIAE------------LTNRTHRF 1200
+AL W D+++ E L F
Sbjct: 1017 YALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAF 1076
Query: 1201 LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV 1260
LE+ +L+ G + RE + + K + +Q + L ++ + E +E+ I
Sbjct: 1077 LEQMMSLE--GAVKAAREQLQRL-NKGARCAQAGSQKTCTQ-LADLEAVLESSEEEILHA 1132
Query: 1261 TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS 1320
++A +E+ + S + L TEA +L + ++ A + I + R L S
Sbjct: 1133 AAILASLEI-----PQEGPSQPTKWSHLATEARALARSHRDTATK---IAATAWRALLAS 1184
Query: 1321 ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE 1380
T Y + E RV T RD +ED E ++ K + A +L E
Sbjct: 1185 NTSYALLWNLLEGRVALET------------QRD-LEDRYQEVQAAQKALRTAVAEVLPE 1231
Query: 1381 ---LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVA 1437
+ +Q + A + PGA ++ + E+ + +
Sbjct: 1232 AESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKT--------VASWQ 1283
Query: 1438 HNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSN 1497
H A + A L + L + E L+K+ EA+ +A S + + + +
Sbjct: 1284 HMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLL---- 1339
Query: 1498 EELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQV 1557
ADL+ ++ L+ P LQ + + +R
Sbjct: 1340 ------------------ADLEGMK------LQFPRPKDQAALQRKADSVSDR------- 1368
Query: 1558 EVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQAD 1617
+L + +AE +L A S SA ++ +A+V A+ + K A
Sbjct: 1369 --LLADTRKKTKQAERMLGNAAPLSSSAK-------------KKGREAEVLAKDSAKLAK 1413
Query: 1618 EDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVY 1677
++ + T+ ++ TL ASQ++ E +EL+ EAE + +
Sbjct: 1414 ALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELE--------EAERVGAGLS 1465
Query: 1678 TVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEES-ADARRKAEMLQNEAKTLLAQANSK 1736
++Q + + +L+ +++ + + L + T ++ A A + + + L S
Sbjct: 1466 EMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGSPGSL 1525
Query: 1737 LQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSL 1771
+ L LE++ + + ++ +LA + + ++L
Sbjct: 1526 QRKLSLLEQESQQQELQIQGFESDLAEIRADKQNL 1560
Score = 246 bits (629), Expect = 1e-64
Identities = 162/492 (32%), Positives = 233/492 (47%), Gaps = 58/492 (11%)
Query: 35 CYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI-VSHLQEDKKCFICNSQDPYHETLNPDS 93
C P + GR + S TCG PE +C V C C++ DP
Sbjct: 35 CLPVFENAAFGRLAQAS--HTCG-SPPEDFCPHVGAAGAGAHCQRCDAADPQR------- 84
Query: 94 HLIENVVTTFAPNRLKIWWQSEN---GVE---NVTIQLDLEAEFHFTHLIMTFKTFRPAA 147
H + +T F WWQS + GV+ +V I L L + T++ + F T RP +
Sbjct: 85 HHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPES 144
Query: 148 MLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDD---IICDSRYSDIEPSTEGE 204
I + S W Y++++ C+ ++ ++ +D C S +SDI P + G
Sbjct: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204
Query: 205 VIFRALD---PAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYA 261
V F L+ A+ E+ SP +Q + T L I +L+T GD++ ++ + YYYA
Sbjct: 205 VAFSTLEGRPSAYNFEE--SPGLQEWVTSTELLISLDRLNTFGDDIFKDP-KVLQSYYYA 261
Query: 262 VYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPW 321
V D V G C C GHASEC P +V G + C C+HNT G +CE C+ F+ D PW
Sbjct: 262 VSDFSVGGRCKCNGHASECGP------DVAGQLA--CRCQHNTTGTDCERCLPFFQDRPW 313
Query: 322 RPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFY 381
++ C CNC+ S C FD ++ +TG+ GG C C+ +T G +CE+C+ +
Sbjct: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENF 371
Query: 382 YQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCK 441
Y D R P C+ C C AGS + CD G C CK V G CD C
Sbjct: 372 YHW---DPRMP--CQPCDCQSAGSLHLQ-CDD---------TGTCACKPTVTGWKCDRCL 416
Query: 442 EGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLS 501
GF+ LS GC+ C CNP G++ + CD +G C CK V G CD+C P + L
Sbjct: 417 PGFHSLSEG---GCRPCTCNPAGSL---DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQ 470
Query: 502 -NDLDGCRPCDC 512
++ GC C C
Sbjct: 471 PHNPAGCSSCFC 482
Score = 185 bits (470), Expect = 3e-46
Identities = 112/332 (33%), Positives = 151/332 (45%), Gaps = 45/332 (13%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG----CKPCECHLQGS 828
C C+ G+ CDPN G C C + G +C RC PG +G +G C+PC C Q +
Sbjct: 707 CTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSA 762
Query: 829 VNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNGHAD----- 874
C HC G R+C+ C G +G P C CQC+G+ D
Sbjct: 763 CTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVG 822
Query: 875 DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPC-PDGPDSGRQFARS 932
+CDP++G CL C T G +CE C G+YG + D C PC C P G S +
Sbjct: 823 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM---P 879
Query: 933 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDK 992
C DPVT Q C C P C C G+F + G C+ C+CH + + C
Sbjct: 880 C--DPVTGQ--CSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHPL--GSQEDQCHP 931
Query: 993 ETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
+TG+C C G+ C C+ G++G ++ + CR C C+ LG C+ G
Sbjct: 932 KTGQC-TCRPGVTGQACDRCQLGFFGFSI-KGCRACRCSPLGAASAQCH--------ENG 981
Query: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGTGCDPC 1084
C+C P G CDRC N + A GT C C
Sbjct: 982 TCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 149 bits (375), Expect = 3e-35
Identities = 102/332 (30%), Positives = 130/332 (39%), Gaps = 75/332 (22%)
Query: 916 PCPCPDGP----DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVG- 970
P P P GP + AR P + C C GY G C+ CA GY + G
Sbjct: 641 PGPSPAGPVFLTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGP 700
Query: 971 -GSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDAL---QQDCR 1026
SC PC C+ + CD TG C+ C +HTEG C+ C G+YG+ DC+
Sbjct: 701 YASCVPCTCNQH------GTCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQ 753
Query: 1027 KCVC---NYLGTVQE-------HC----NGSDCQ-------------------------- 1046
C C + T+ E HC G C+
Sbjct: 754 PCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS 813
Query: 1047 ----------CDKATGQCL-CLPNVIGQNCDRCAPNTWQLA----SGTGCDPCNCNAAHS 1091
CD +G CL CL N G +C+ C + A C PC+C+ S
Sbjct: 814 GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGS 873
Query: 1092 FGPS--CNEFTGQCQCMPGFGGRTCSECQELFWG-DPDVECRACDCDPRGIETPQCDQST 1148
C+ TGQC C+P R CS C F+ P CR+C C P G + QC T
Sbjct: 874 VSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKT 933
Query: 1149 GQCVCVEGVEGPRCDKCTRGYSGV-FPDCTPC 1179
GQC C GV G CD+C G+ G C C
Sbjct: 934 GQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 965
Score = 143 bits (361), Expect = 1e-33
Identities = 79/257 (30%), Positives = 119/257 (46%), Gaps = 25/257 (9%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C+C H+T+G +CE C+ ++ P+ ++ C+ C C S + +
Sbjct: 720 GICVCSHHTEGPSCERCLPGFYGNPF----AGQADDCQPCPCPGQSACTTIPESREV--- 772
Query: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDSY 414
VC C GR CE C ++ P P C +C C N G CD
Sbjct: 773 -----VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDP- 826
Query: 415 TDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYD--LSSEDPFGCKSCACNPLGTIPGGNP 471
++G C RC N G+HC+ C+EGFY L+ C C+C+P G++ P
Sbjct: 827 -------LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP 879
Query: 472 CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSC 531
CD TG C C VT + C +C P + L GCR C C G+ + C ++GQC+C
Sbjct: 880 CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG-RGCRSCKCHPLGSQEDQCHPKTGQCTC 938
Query: 532 RPHMIGRQCNEVEPGYY 548
RP + G+ C+ + G++
Sbjct: 939 RPGVTGQACDRCQLGFF 955
Score = 130 bits (328), Expect = 9e-30
Identities = 79/218 (36%), Positives = 107/218 (49%), Gaps = 23/218 (10%)
Query: 334 KCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHP--ERDIRD 391
+C CN H+ C D+A LA CQHNT G +CE+C PF+ P
Sbjct: 270 RCKCNGHASECGPDVAGQLACR---------CQHNTTGTDCERCLPFFQDRPWARGTAEA 320
Query: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGFYDLSSE 450
+ C C C +G E D STG G+C C+ + G HC+ C+E FY
Sbjct: 321 AHECLPCNC--SGRSEECTFDRELFRSTGH-GGRCHHCRDHTAGPHCERCQENFYHWDPR 377
Query: 451 DPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPC 510
P C+ C C G++ CD +TG C CK VTG CD+CLP LS GCRPC
Sbjct: 378 MP--CQPCDCQSAGSLH--LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEG--GCRPC 430
Query: 511 DCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
C+ G+L+ +C SG+C C+ ++ G C+ PG +
Sbjct: 431 TCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTF 467
Score = 126 bits (317), Expect = 2e-28
Identities = 64/155 (41%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 771 LACECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS-GCKPCECHLQG 827
+ C C PQGS+S CDP GQC C P+V R C+RC PG F P GC+ C+CH G
Sbjct: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
Query: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF--PSCQPCQCN--GHADDCDPVTGEC 883
S C+P TGQC C GV + CDRC G +GF C+ C+C+ G A G C
Sbjct: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTC 983
Query: 884 LNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCP 918
+ C+ G+ C+RC ++ + G HC+ CP
Sbjct: 984 V-CRPGFEGYKCDRCHDNFF---LTADGTHCQQCP 1014
Score = 112 bits (279), Expect = 4e-24
Identities = 68/198 (34%), Positives = 86/198 (43%), Gaps = 20/198 (10%)
Query: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQCHNNID- 983
A C D V QLAC C G+ C+ C + P +E C PC C +
Sbjct: 277 ASECGPD-VAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEE 335
Query: 984 -TTDPEACDK--ETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC 1040
T D E GRC C HT G HC+ C+ +Y + C+ C C G++
Sbjct: 336 CTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLH--- 392
Query: 1041 NGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFT 1100
QCD TG C C P V G CDRC P L+ G GC PC CN A S +C+ +
Sbjct: 393 ----LQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSL-DTCDPRS 445
Query: 1101 GQCQCMPGFGGRTCSECQ 1118
G+C C G C C+
Sbjct: 446 GRCPCKENVEGNLCDRCR 463
Score = 102 bits (253), Expect = 4e-21
Identities = 71/228 (31%), Positives = 95/228 (41%), Gaps = 24/228 (10%)
Query: 867 CQCNGHADDCDP-VTGE-CLNCQDYTMGHNCERCLAGYYGDP----IIGSGDHCRPCPCP 920
C+CNGHA +C P V G+ CQ T G +CERCL + P + C PC C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC- 329
Query: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
G F R ++ C G C+ C ++ + CQPC C +
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM--PCQPCDCQS 387
Query: 981 NIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC 1040
CD +TG C C G C C G++ + + CR C CN G++
Sbjct: 388 AGSLH--LQCD-DTGTCA-CKPTVTGWKCDRCLPGFHSLS-EGGCRPCTCNPAGSLDT-- 440
Query: 1041 NGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLA--SGTGCDPCNC 1086
CD +G+C C NV G CDRC P T+ L + GC C C
Sbjct: 441 ------CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 99.0 bits (245), Expect = 4e-20
Identities = 68/226 (30%), Positives = 101/226 (44%), Gaps = 22/226 (9%)
Query: 969 VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQ 1023
VGG C+ C+ + P+ + RC ++T G C+ C ++ D +
Sbjct: 267 VGGRCK---CNGHASECGPDVAGQLACRCQ---HNTTGTDCERC-LPFFQDRPWARGTAE 319
Query: 1024 DCRKCV-CNYLGTVQEHCNGSDCQCDKATG---QCL-CLPNVIGQNCDRCAPNTWQLASG 1078
+C+ CN G +E C D + ++TG +C C + G +C+RC N +
Sbjct: 320 AAHECLPCNCSGRSEE-CT-FDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR 377
Query: 1079 TGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRG 1138
C PC+C +A S C++ TG C C P G C C F + CR C C+P G
Sbjct: 378 MPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG 436
Query: 1139 IETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFP-DCTPCHQCF 1183
CD +G+C C E VEG CD+C G + P + C CF
Sbjct: 437 -SLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCF 481
Score = 95.5 bits (236), Expect = 4e-19
Identities = 43/109 (39%), Positives = 56/109 (51%), Gaps = 7/109 (6%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
C+C GSL CD G C C+P V G C+RC PG GC+PC C+ GS++
Sbjct: 383 CDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT- 440
Query: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCNGHADDC 876
C+P +G+C C + V CDRC PG + C C C GH+ C
Sbjct: 441 CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVC 489
Score = 95.1 bits (235), Expect = 5e-19
Identities = 80/277 (28%), Positives = 105/277 (37%), Gaps = 86/277 (31%)
Query: 780 SLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQ 839
S+ C NG +C P+V G+ RC T G
Sbjct: 266 SVGGRCKCNGHASECGPDVAGQLACRCQHNTTG--------------------------- 298
Query: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDC---------DPVT 880
C+RCLP P C PC C+G +++C
Sbjct: 299 ---------TDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
Query: 881 GECLNCQDYTMGHNCERCLAGYY-GDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVT 939
G C +C+D+T G +CERC +Y DP + C+PC C S C D T
Sbjct: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRM----PCQPCDC----QSAGSLHLQC-DDTGT 400
Query: 940 LQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCH--NNIDTTDPEACDKETGRC 997
C C P G +CD C G F + SE G C+PC C+ ++DT CD +GRC
Sbjct: 401 ----CACKPTVTGWKCDRCLPG-FHSLSE--GGCRPCTCNPAGSLDT-----CDPRSGRC 448
Query: 998 LKCLYHTEGEHCQFCRFGYYGDALQ----QDCRKCVC 1030
C + EG C CR G + LQ C C C
Sbjct: 449 -PCKENVEGNLCDRCRPGTFN--LQPHNPAGCSSCFC 482
Score = 71.2 bits (173), Expect = 8e-12
Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 11/128 (8%)
Query: 426 CRCKLNVEGEHCDVCKEGFY-DLSSEDPFG-CKSCACNPLGTIPGGNPCDSETGHCYCKR 483
C C G+ C+ C G+ ++ P+ C C CN GT CD TG C C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVCSH 726
Query: 484 LVTGQHCDQCLPEHWG--LSNDLDGCRPCDCDLGGALNNSCFAESGQCS-CRPHMIGRQC 540
G C++CLP +G + D C+PC C A + C+ C P GR+C
Sbjct: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC 786
Query: 541 NEVEPGYY 548
+ G++
Sbjct: 787 EVCDDGFF 794
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 467 PGGNPCDSETGHCYCKRLVTGQHCDQCLP---EHWGLSNDLDGCRPCDCDLGGALNNSCF 523
PG +P S C C TGQ C+ C P C PC C+ G +C
Sbjct: 661 PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHG----TCD 716
Query: 524 AESGQCSCRPHMIGRQCNEVEPGYY 548
+G C C H G C PG+Y
Sbjct: 717 PNTGICVCSHHTEGPSCERCLPGFY 741
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 306 bits (783), Expect = 2e-82
Identities = 150/352 (42%), Positives = 197/352 (55%), Gaps = 25/352 (7%)
Query: 840 CHCFQGVYARQCDRCLPGHWGFPS------CQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
C C G C+ C P H C+PCQC GHA+ CD VTGECLNC+D+T G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-CDPGYIG 952
C++CL G+YG+P G+ + C+PC CP S F+ +C+ D +L L C C GY G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNN-FSPTCHLDR-SLGLICDGCPVGYTG 841
Query: 953 SRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
RC+ CA GYFG PS GGSCQPCQC++N+D + P +CD +G CL C T G +C+ C
Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901
Query: 1013 RFGYYGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
GY+GDA+ ++C+ C CN G+ E C+ TGQC C NV GQ CD+C
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQ-------TGQCECRANVQGQRCDKCKAG 954
Query: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 1131
T+ L S GC PCNCN+ S C E +GQC C PG G+ C C ++ + C A
Sbjct: 955 TFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTA 1013
Query: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC---TRGYSGVFPDCTPCH 1180
C+C G CD TG+C+C G +C KC T G+S + C C+
Sbjct: 1014 CECSHLG---NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS-ITTGCKACN 1061
Score = 259 bits (662), Expect = 2e-68
Identities = 167/504 (33%), Positives = 222/504 (44%), Gaps = 110/504 (21%)
Query: 759 IFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAP------GTFG 812
IF +S++ ++ ++ D GS+++ + CQC P G +C C P GT
Sbjct: 697 IFRLSSVNLESAVSYPTD--GSIAAAVEV----CQCPPGYTGSSCESCWPRHRRVNGTI- 749
Query: 813 FGPSGCKPCEC--HLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFPS------ 863
FG C+PC+C H + C+ VTG+C +C CD+CLPG +G P+
Sbjct: 750 FG-GICEPCQCFGHAES-----CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED 803
Query: 864 CQPCQC------NGHADDC--DPVTG-ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHC 914
CQPC C N + C D G C C G CERC GY+G P + G C
Sbjct: 804 CQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS-C 862
Query: 915 RPCPCPDG-----PDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEV 969
+PC C D P S + SC +C PG G C+ CA GYFG+ +
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSC----------LICKPGTTGRYCELCADGYFGDAVD- 911
Query: 970 GGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCV 1029
+CQPC+C N + E C +TG+C +C + +G+ C C+ G +G + C C
Sbjct: 912 AKNCQPCRC--NAGGSFSEVCHSQTGQC-ECRANVQGQRCDKCKAGTFGLQSARGCVPCN 968
Query: 1030 CNYLGTVQEHCNGSD---CQ----------------------------------CDKATG 1052
CN G+ C S CQ CD TG
Sbjct: 969 CNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTG 1028
Query: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
+C+C PN IG+ C +CAPNTW + TGC CNC+ S CN TGQC C P F G
Sbjct: 1029 RCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 1113 TCSECQELFWGDPDVECRACDCDPRGIETPQCD---------QSTGQCVCVEGVEGPRCD 1163
C+EC W P C CDC G + CD TGQC C VEG CD
Sbjct: 1089 KCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD 1146
Query: 1164 KCTRGYSGVFP----DCTPCHQCF 1183
+C G G+ C+ C+ CF
Sbjct: 1147 RCRPGKFGLDAKNPLGCSSCY-CF 1169
Score = 229 bits (584), Expect = 2e-59
Identities = 166/552 (30%), Positives = 243/552 (44%), Gaps = 64/552 (11%)
Query: 3 LLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPE 62
LL LL L +A+ R Q+ S + +PA L + ++ +TCG PE
Sbjct: 8 LLLLLLSGGLGGVQAQ-RPQQQRQSQAHQQRGLFPAV--LNLASNALITTNATCGEKGPE 64
Query: 63 PYC-IVSHLQ----EDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQS--- 114
YC +V H+ + +C ICN +P ++ I+ T WWQS
Sbjct: 65 MYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNT---------WWQSPSI 115
Query: 115 ENGVEN--VTIQLDLEAEFHFTHLIM-TFKTFRPAAMLIERSSDFG--KTWGVYRYFAYD 169
+NG+E VTI LDL+ F ++I+ + RP ++ERS D K W + +
Sbjct: 116 KNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTE 175
Query: 170 CEASF---PGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQN 226
C + P K D++IC S YS I P GE+ ++ +DP SP +
Sbjct: 176 CLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDP-SPELLE 234
Query: 227 LLKITNLRIKFVKLHTLG-DNLLDSRMEIRE-------KYYYAVYDMVVRGNCFCYGHAS 278
+R++F ++ TL D ++ + + RE +YYY+V D+ V G C CYGHA
Sbjct: 235 FTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHAR 294
Query: 279 ECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCN 338
C P+D + C C HNT G +C+ C +H PWR C+ CNC+
Sbjct: 295 AC-PLDPATNK------SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCH 347
Query: 339 EHSISCHFD-------MAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRD 391
+ C++D +++ + + GGVC +C NT G NCE C +++
Sbjct: 348 GKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNY 407
Query: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSED 451
P C+ C CDP GS NE GL G C CK G CD C G+
Sbjct: 408 PRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-- 465
Query: 452 PFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPC 510
CK+C C+ LG+ +PC G C CK V G C +C + L D GC C
Sbjct: 466 ---CKACNCSGLGS-KNEDPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518
Query: 511 DCDLGGALNNSC 522
C ++N C
Sbjct: 519 FC---SGVSNRC 527
Score = 171 bits (434), Expect = 4e-42
Identities = 99/291 (34%), Positives = 137/291 (47%), Gaps = 39/291 (13%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS-GCKPCECHLQGSVNA 831
C C+ GS S VC GQC+CR NV G+ C++C GTFG + GC PC C+ GS +
Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSF 977
Query: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDY 889
C +GQC C GV ++CDRC G++ F C C+C+ ++CDP TG C+ C
Sbjct: 978 DCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPN 1035
Query: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
T+G C +C +G I C+ C C Q + Q C C P
Sbjct: 1036 TIGEKCSKCAPNTWGHSITTG---CKACNCSTVGSLDFQCNVNTGQ--------CNCHPK 1084
Query: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRC--------LKCL 1001
+ G++C +C+ G++ P C C C + TD CD ET +C C
Sbjct: 1085 FSGAKCTECSRGHWNYPR-----CNLCDCF--LPGTDATTCDSETKKCSCSDQTGQCTCK 1137
Query: 1002 YHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
+ EG HC CR G +G D + N LG +C G+ QC +A G
Sbjct: 1138 VNVEGIHCDRCRPGKFG----LDAK----NPLGCSSCYCFGTTTQCSEAKG 1180
Score = 156 bits (394), Expect = 2e-37
Identities = 180/836 (21%), Positives = 312/836 (37%), Gaps = 164/836 (19%)
Query: 937 PVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG--------SCQPCQCHNNIDTTDPE 988
P L C C GY G C+ C G++ S+ GG +C PCQC+ +
Sbjct: 1373 PADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH-----SS 1427
Query: 989 ACDKETGRCLKCLYHTEGEHCQFCRFGYYG--DALQQDCRKCVCNYLGT---VQEHCNGS 1043
CD ET C C +HT G+ C+ C GYYG L DC++C C + + C
Sbjct: 1428 LCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE 1487
Query: 1044 DCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG--CDPCNCNAAHSFGPSCNEFTG 1101
+ T C GQ C+RCAP G C C C+ S C+ TG
Sbjct: 1488 GLDDYRCTA---CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTG 1544
Query: 1102 QCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR 1161
C C PG GR C C+ + EC C
Sbjct: 1545 FCTCRPGATGRKCDGCKH-WHAREGWECVFCG---------------------------- 1575
Query: 1162 CDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVD 1221
D+CT +++ +L R + ++ ++G + + +
Sbjct: 1576 -DECT--------------------GLLLGDLA----RLEQMVMSINLTGPLPAPYKMLY 1610
Query: 1222 SVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNST 1281
+E E+K +L+ A E L + AE + + M ++ + + T+ T
Sbjct: 1611 GLENMTQELKHLLSPQRAPE------RLIQLAEGNLNTLVTEMNELLTRATKVTADGEQT 1664
Query: 1282 AKELDSLQTEAESLDNTVKELAEQLEFIKNSDIR--GALDSITKYFQMSLEAEERVNAST 1339
++ + T A+SL +KELA E + I+ L + + F+ +LE ++
Sbjct: 1665 GQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQK----- 1719
Query: 1340 TEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCG 1399
++Q ++++ + KE E++ + L K++ L
Sbjct: 1720 -----EIDQ------MIKELRRKNLETQKEIAEDELVAAEALLKKVKKLF---------- 1758
Query: 1400 TPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVE 1459
G S E E + R + K N A DL ++ + E
Sbjct: 1759 ---GESRGENEEMEKDLREKLADYK--------------NKVDDAWDLLREATDKIREAN 1801
Query: 1460 QLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLD 1519
+L V++ + A E K KE ++ ++ N +K+ + L + + D
Sbjct: 1802 RLF-AVNQKNMTALEKK-------------KEAVESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 1520 SIEAVAN--EVLKMEMPSTPQQLQNLTEDI------RERVESLSQVEVILQHSAADIARA 1571
I ++ + E ++ ++P ++L + +D+ R+ E +SQ E A
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVL 1907
Query: 1572 EMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE 1631
+ +L+EAK S +AT +K+ ++EAEK A+ +A + G + LL
Sbjct: 1908 DGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLL---- 1963
Query: 1632 SETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLD 1691
+E Q+ + ++L +N ++ + D+ +TL+
Sbjct: 1964 ------KEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLN 2017
Query: 1692 GELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKY 1747
L K + N A K + D KA + AK +LAQ Q L L++ Y
Sbjct: 2018 DTLG-KLSAIPNDTAAKLQAVKD---KARQANDTAKDVLAQITELHQNLDGLKKNY 2069
Score = 145 bits (365), Expect = 4e-34
Identities = 104/373 (27%), Positives = 140/373 (37%), Gaps = 126/373 (33%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
C C+GHA C V G C+ C+ +T G C+ C+ ++ P +G S
Sbjct: 757 CQCFGHAESCDDVT-----------GECLNCKDHTGGPYCDKCLPGFYG---EPTKG-TS 801
Query: 330 NACKKCNC------NEHSISCHFDMAV----------------------YLATGNVSGGV 361
C+ C C N S +CH D ++ Y +V GG
Sbjct: 802 EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS 861
Query: 362 CDDCQHN------------------------TMGRNCEQCKPFYYQHPERDIRDPNFCER 397
C CQ N T GR CE C Y+ D D C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF----GDAVDAKNCQP 917
Query: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
C C+ GS +E +C S T GQC C+ NV+G+ CD CK G + L S GC
Sbjct: 918 CRCNAGGSFSE-VCHSQT--------GQCECRANVQGQRCDKCKAGTFGLQSAR--GCVP 966
Query: 458 CACNPLGT-------------IPG-----------------------------GNPCDSE 475
C CN G+ PG GN CD +
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPK 1026
Query: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
TG C C G+ C +C P WG S GC+ C+C G+L+ C +GQC+C P
Sbjct: 1027 TGRCICPPNTIGEKCSKCAPNTWGHS-ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKF 1085
Query: 536 IGRQCNEVEPGYY 548
G +C E G++
Sbjct: 1086 SGAKCTECSRGHW 1098
Score = 133 bits (334), Expect = 2e-30
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 18/188 (9%)
Query: 839 QCHCFQGVYARQCDRCLPGHWGFPS-------------CQPCQCNGHADDCDPVTGECLN 885
+C C G C+ CLPG + S C PCQCNGH+ CDP T C N
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 886 CQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
CQ +T G CERC GYYG + G + C+ C CP S F+ SC + +
Sbjct: 1439 CQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACP-LISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 946 CDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
C GY G C+ CA GY G+P GGSCQ C+C + + P CD TG C C
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECEC--DPYGSLPVPCDPVTGFC-TCRPGAT 1553
Query: 1006 GEHCQFCR 1013
G C C+
Sbjct: 1554 GRKCDGCK 1561
Score = 127 bits (319), Expect = 1e-28
Identities = 75/254 (29%), Positives = 119/254 (46%), Gaps = 24/254 (9%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C C G +CE C + + G C+ C C H+ SC D+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGG----ICEPCQCFGHAESCD-DVT-------- 770
Query: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
G C +C+ +T G C++C P +Y P + + C+ C C N + D
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFSPTCHLDR 826
Query: 418 STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPL--GTIPGGNPCDSE 475
S GLI C + G C+ C EG++ S C+ C CN +IPG CDS
Sbjct: 827 SLGLICDGC--PVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS--CDSL 882
Query: 476 TGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
+G C CK TG++C+ C ++G + D C+PC C+ GG+ + C +++GQC CR +
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 535 MIGRQCNEVEPGYY 548
+ G++C++ + G +
Sbjct: 943 VQGQRCDKCKAGTF 956
Score = 110 bits (274), Expect = 2e-23
Identities = 65/205 (31%), Positives = 93/205 (45%), Gaps = 25/205 (12%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPA---EGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
C C GL+CE C+ ++ L +P G C C CN HS C + ++
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI---- 1435
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
C +CQH+T G CE+C YY + PN C++C C S N S
Sbjct: 1436 -------CQNCQHHTAGDFCERCALGYYGIVKGL---PNDCQQCACPLISSSNNF---SP 1482
Query: 415 TDFSTGLIAGQCR-CKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
+ + GL +C C EG++C+ C G+ C+ C C+P G++P PCD
Sbjct: 1483 SCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPV--PCD 1540
Query: 474 SETGHCYCKRLVTGQHCDQCLPEHW 498
TG C C+ TG+ CD C +HW
Sbjct: 1541 PVTGFCTCRPGATGRKCDGC--KHW 1563
Score = 100 bits (249), Expect = 1e-20
Identities = 73/269 (27%), Positives = 103/269 (38%), Gaps = 57/269 (21%)
Query: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA 989
AR+C DP T + C C+ G CD C G+ P G +C EA
Sbjct: 293 ARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC---------EA 343
Query: 990 CDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDK 1049
C+ H + E C YY + + + R N G ++ G C
Sbjct: 344 CN----------CHGKAEEC------YYDENVAR--RNLSLNIRG---KYIGGGVC---- 378
Query: 1050 ATGQCLCLPNVIGQNCDRCAPNTWQLASGTG-----CDPCNCNAAHSFGPSCNE------ 1098
C N G NC+ C ++ + C PC+C+ S C +
Sbjct: 379 ----INCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHAR 434
Query: 1099 ---FTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVE 1155
G C C GFGG +C C + G PD C+AC+C G+ + D G C+C E
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYPD--CKACNCS--GLGSKNEDPCFGPCICKE 490
Query: 1156 GVEGPRCDKCTRGYSGVFPD-CTPCHQCF 1183
VEG C +C G+ + D C +CF
Sbjct: 491 NVEGGDCSRCKSGFFNLQEDNWKGCDECF 519
Score = 93.2 bits (230), Expect = 2e-18
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 35/241 (14%)
Query: 335 CNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPER--DIRDP 392
C C H+ +C D A + C+ C+HNT G +C+QC P ++Q P R
Sbjct: 287 CICYGHARACPLDPATNKSR-------CE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 393 NFCERCTCDPAGSQ---NEGICDSYTDFSTG---LIAGQC-RCKLNVEGEHCDVCKEGFY 445
CE C C + +E + + + G C C N G +C+ C +GF+
Sbjct: 339 TECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF 398
Query: 446 ---DLSSEDPFGCKSCACNPLGTIPGGNPCDSE-------TGHCYCKRLVTGQHCDQCLP 495
+S P C+ C C+P+G++ D + G C+CK G CD+C
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCAR 458
Query: 496 EHWGLSNDLDGCRPCDCD-LGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDH 554
+ G + C+ C+C LG + CF G C C+ ++ G C+ + G++ D+
Sbjct: 459 GYTGYPD----CKACNCSGLGSKNEDPCF---GPCICKENVEGGDCSRCKSGFFNLQEDN 511
Query: 555 Y 555
+
Sbjct: 512 W 512
Score = 93.2 bits (230), Expect = 2e-18
Identities = 84/305 (27%), Positives = 101/305 (33%), Gaps = 91/305 (29%)
Query: 277 ASECAP----VDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNAC 332
A C P G EV G C CR N +G C+ C L +++ C
Sbjct: 912 AKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL-------QSARGC 964
Query: 333 KKCNCNEH---SISCHFDMAVYLATGNVSGGVCDDCQH---------------------- 367
CNCN S C + G V+G CD C H
Sbjct: 965 VPCNCNSFGSKSFDCEESGQCWCQPG-VTGKKCDRCAHGYFNFQEGGCTACECSHLGNNC 1023
Query: 368 -----------NTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTD 416
NT+G C +C P + H C+ C C GS D
Sbjct: 1024 DPKTGRCICPPNTIGEKCSKCAPNTWGHSIT-----TGCKACNCSTVGS---------LD 1069
Query: 417 FSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSET 476
F + GQC C G C C G ++ C C C GT CDSET
Sbjct: 1070 FQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGT--DATTCDSET 1122
Query: 477 ---------GHCYCKRLVTGQHCDQCLPEHWGL--SNDLDGCRPCDCDLGGALNNSCFAE 525
G C CK V G HCD+C P +GL N L GC C CF
Sbjct: 1123 KKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPL-GCSSC----------YCFGT 1171
Query: 526 SGQCS 530
+ QCS
Sbjct: 1172 TTQCS 1176
Score = 89.7 bits (221), Expect = 2e-17
Identities = 78/278 (28%), Positives = 107/278 (38%), Gaps = 56/278 (20%)
Query: 867 CQCNGHADDC--DPVTGEC-LNCQDYTMGHNCERCLAGYYGDP----IIGSGDHCRPCPC 919
C C GHA C DP T + C+ T G +C++C G++ P + C C C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 920 PDGPDSGRQFARSCYQDP------VTLQL--------ACV-CDPGYIGSRCDDCASGYFG 964
G+ A CY D ++L + C+ C G C+ C G+F
Sbjct: 347 -----HGK--AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF- 398
Query: 965 NPSEVGGS----CQPCQCH-----NNIDTTDPEACDK--ETGRCLKCLYHTEGEHCQFCR 1013
P V + CQPC C N + D + + G C C G C C
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCA 457
Query: 1014 FGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTW 1073
GY G DC+ C C+ LG+ E D G C+C NV G +C RC +
Sbjct: 458 RGYTG---YPDCKACNCSGLGSKNE---------DPCFGPCICKENVEGGDCSRCKSGFF 505
Query: 1074 QLASGT--GCDPCNCNAAHSFGPSCNEFTGQCQCMPGF 1109
L GCD C C+ + S G+ Q M G+
Sbjct: 506 NLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Score = 87.4 bits (215), Expect = 1e-16
Identities = 78/291 (26%), Positives = 114/291 (39%), Gaps = 74/291 (25%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAP---------GTFGFGPSGCKPCE 822
AC DP N +C+C N G +C++C P GTF + C+ C
Sbjct: 295 ACPLDPA--------TNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF-LTKTECEACN 345
Query: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGE 882
CH + +C+ + V R + G + G G
Sbjct: 346 CHGKAE----------ECYYDENVARRNLSLNIRGKY---------IGG---------GV 377
Query: 883 CLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPC-PCPDGPDSGRQFARSCYQDPVTLQ 941
C+NC T G NCE C G++ P S ++ RPC PC P C +D +
Sbjct: 378 CINCTQNTAGINCETCTDGFF-RPKGVSPNYPRPCQPCHCDPIG--SLNEVCVKDEKHAR 434
Query: 942 L-----ACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGR 996
+C C G+ G CD CA GY G P C+ C C + + + + + C G
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYP-----DCKACNC-SGLGSKNEDPC---FGP 485
Query: 997 CLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGS 1043
C+ C + EG C C+ G++ LQ+D C +C C+ V C S
Sbjct: 486 CI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCDECFCS---GVSNRCQSS 530
Score = 86.7 bits (213), Expect = 2e-16
Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 22/189 (11%)
Query: 364 DCQHNTMGRNCEQCKPFYYQ---HPERDIRDPNF--CERCTCDPAGSQNEGICDSYTDFS 418
DC G +CE C P +Y+ P P C C C+ S +CD T
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS----LCDPETSIC 1436
Query: 419 TGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP-CDSETG 477
C+ + G+ C+ C G+Y + P C+ CAC + + +P C +E
Sbjct: 1437 QN-------CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGL 1489
Query: 478 HCY----CKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQCSCR 532
Y C R GQ+C++C P + G + G C+ C+CD G+L C +G C+CR
Sbjct: 1490 DDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549
Query: 533 PHMIGRQCN 541
P GR+C+
Sbjct: 1550 PGATGRKCD 1558
Score = 76.3 bits (186), Expect = 3e-13
Identities = 59/194 (30%), Positives = 74/194 (38%), Gaps = 38/194 (19%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFGF---------GPS--GCKPCECHLQGSVNAFCNPVTGQ 839
+C C G +C C PG + GP+ C PC+C+ S+ C+P T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 840 C-HCFQGVYARQCDRCLPGHWGF-----PSCQPCQC------NGHADDCDPV---TGECL 884
C +C C+RC G++G CQ C C N + C C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
C G CERC GY G P G C+ C C D C DPVT C
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSP-GNPGGSCQECEC----DPYGSLPVPC--DPVT--GFC 1546
Query: 945 VCDPGYIGSRCDDC 958
C PG G +CD C
Sbjct: 1547 TCRPGATGRKCDGC 1560
Score = 72.4 bits (176), Expect = 4e-12
Identities = 77/253 (30%), Positives = 104/253 (41%), Gaps = 49/253 (19%)
Query: 343 SCHFDMAV-YLATGNVSGGV--CDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNF---CE 396
S + + AV Y G+++ V C C G +CE C P + R + F CE
Sbjct: 702 SVNLESAVSYPTDGSIAAAVEVCQ-CPPGYTGSSCESCWPRH-----RRVNGTIFGGICE 755
Query: 397 RCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDL----SSED 451
C C CD T G+C CK + G +CD C GFY +SED
Sbjct: 756 PCQCFGHAES----CDDVT--------GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED 803
Query: 452 PFGCKSCACNPLGTIPGGNPCDSETGHCY---------CKRLVTGQHCDQCLPEHWGLSN 502
C+ CAC PL IP N S T H C TG C++C ++G +
Sbjct: 804 ---CQPCAC-PLN-IPSNN--FSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856
Query: 503 DLDG-CRPCDCD--LGGALNNSCFAESGQCS-CRPHMIGRQCNEVEPGYYFATLDHYLYE 558
G C+PC C+ L ++ SC + SG C C+P GR C GY+ +D +
Sbjct: 857 VPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQ 916
Query: 559 AEEANLGPGVSIV 571
N G S V
Sbjct: 917 PCRCNAGGSFSEV 929
Score = 66.6 bits (161), Expect = 2e-10
Identities = 52/172 (30%), Positives = 69/172 (40%), Gaps = 31/172 (18%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELC-MDFYHDLPWRPAEGRNS 329
C C GH+S C P + C+H+T G CE C + +Y + P
Sbjct: 1420 CQCNGHSSLCDPETSICQN----------CQHHTAGDFCERCALGYYGIVKGLP------ 1463
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
N C++C C S S +F + +A G + C C G+ CE+C P Y P
Sbjct: 1464 NDCQQCACPLISSSNNFSPSC-VAEG-LDDYRCTACPRGYEGQYCERCAPGYTGSPG--- 1518
Query: 390 RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCK 441
C+ C CDP GS CD T F C C+ G CD CK
Sbjct: 1519 NPGGSCQECECDPYGSLPVP-CDPVTGF--------CTCRPGATGRKCDGCK 1561
Score = 64.3 bits (155), Expect = 1e-09
Identities = 45/141 (31%), Positives = 62/141 (43%), Gaps = 24/141 (17%)
Query: 425 QCRCKLNVEGEHCDVCKEGFYDLSSEDPFG---------CKSCACNPLGTIPGGNPCDSE 475
+C C L G C+ C GFY L S+ P G C C CN ++ CD E
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQ-PGGRTPGPTLGTCVPCQCNGHSSL-----CDPE 1432
Query: 476 TGHCY-CKRLVTGQHCDQCLPEHWGLSNDL-DGCRPCDCDLGGALNN---SCFAE---SG 527
T C C+ G C++C ++G+ L + C+ C C L + NN SC AE
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 528 QCSCRPH-MIGRQCNEVEPGY 547
+C+ P G+ C PGY
Sbjct: 1493 RCTACPRGYEGQYCERCAPGY 1513
Score = 60.1 bits (144), Expect = 2e-08
Identities = 31/69 (44%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Query: 794 CRPNVVGRTCNRCAPGTFGF--GPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQ 850
C G+ C RCAPG G P G C+ CEC GS+ C+PVTG C C G R+
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 851 CDRCLPGHW 859
CD C HW
Sbjct: 1557 CDGC--KHW 1563
Score = 52.4 bits (124), Expect = 4e-06
Identities = 39/121 (32%), Positives = 48/121 (39%), Gaps = 16/121 (13%)
Query: 710 CKSLDIFTVGGSGDGVVTNSAW----ETFQRYRCLENSRSVVKTPMTDVCRNIIFSISAL 765
CK+ + TVG N+ F +C E SR P ++C
Sbjct: 1057 CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLC-------DCF 1109
Query: 766 LHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCKPCE 822
L T A CD + S C GQC C+ NV G C+RC PG FG P GC C
Sbjct: 1110 LPGTD-ATTCDSETKKCS-CSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 823 C 823
C
Sbjct: 1168 C 1168
Score = 50.8 bits (120), Expect = 1e-05
Identities = 20/34 (58%), Positives = 21/34 (61%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRC 806
CECDP GSL CDP G C CRP GR C+ C
Sbjct: 1527 CECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831
AC C GS + DP G C C+ NV G C+RC G F K C+
Sbjct: 468 ACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD-------EC 518
Query: 832 FCNPVTGQCHCFQGVYAR 849
FC+ V+ +C Y +
Sbjct: 519 FCSGVSNRCQSSYWTYGK 536
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 306 bits (783), Expect = 2e-82
Identities = 150/352 (42%), Positives = 197/352 (55%), Gaps = 25/352 (7%)
Query: 840 CHCFQGVYARQCDRCLPGHWGFPS------CQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
C C G C+ C P H C+PCQC GHA+ CD VTGECLNC+D+T G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-CDPGYIG 952
C++CL G+YG+P G+ + C+PC CP S F+ +C+ D +L L C C GY G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNN-FSPTCHLDR-SLGLICDGCPVGYTG 841
Query: 953 SRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
RC+ CA GYFG PS GGSCQPCQC++N+D + P +CD +G CL C T G +C+ C
Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901
Query: 1013 RFGYYGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
GY+GDA+ ++C+ C CN G+ E C+ TGQC C NV GQ CD+C
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQ-------TGQCECRANVQGQRCDKCKAG 954
Query: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 1131
T+ L S GC PCNCN+ S C E +GQC C PG G+ C C ++ + C A
Sbjct: 955 TFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTA 1013
Query: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC---TRGYSGVFPDCTPCH 1180
C+C G CD TG+C+C G +C KC T G+S + C C+
Sbjct: 1014 CECSHLG---NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS-ITTGCKACN 1061
Score = 259 bits (662), Expect = 2e-68
Identities = 167/504 (33%), Positives = 222/504 (44%), Gaps = 110/504 (21%)
Query: 759 IFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAP------GTFG 812
IF +S++ ++ ++ D GS+++ + CQC P G +C C P GT
Sbjct: 697 IFRLSSVNLESAVSYPTD--GSIAAAVEV----CQCPPGYTGSSCESCWPRHRRVNGTI- 749
Query: 813 FGPSGCKPCEC--HLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFPS------ 863
FG C+PC+C H + C+ VTG+C +C CD+CLPG +G P+
Sbjct: 750 FG-GICEPCQCFGHAES-----CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED 803
Query: 864 CQPCQC------NGHADDC--DPVTG-ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHC 914
CQPC C N + C D G C C G CERC GY+G P + G C
Sbjct: 804 CQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS-C 862
Query: 915 RPCPCPDG-----PDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEV 969
+PC C D P S + SC +C PG G C+ CA GYFG+ +
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSC----------LICKPGTTGRYCELCADGYFGDAVD- 911
Query: 970 GGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCV 1029
+CQPC+C N + E C +TG+C +C + +G+ C C+ G +G + C C
Sbjct: 912 AKNCQPCRC--NAGGSFSEVCHSQTGQC-ECRANVQGQRCDKCKAGTFGLQSARGCVPCN 968
Query: 1030 CNYLGTVQEHCNGSD---CQ----------------------------------CDKATG 1052
CN G+ C S CQ CD TG
Sbjct: 969 CNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTG 1028
Query: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
+C+C PN IG+ C +CAPNTW + TGC CNC+ S CN TGQC C P F G
Sbjct: 1029 RCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 1113 TCSECQELFWGDPDVECRACDCDPRGIETPQCD---------QSTGQCVCVEGVEGPRCD 1163
C+EC W P C CDC G + CD TGQC C VEG CD
Sbjct: 1089 KCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD 1146
Query: 1164 KCTRGYSGVFP----DCTPCHQCF 1183
+C G G+ C+ C+ CF
Sbjct: 1147 RCRPGKFGLDAKNPLGCSSCY-CF 1169
Score = 229 bits (584), Expect = 2e-59
Identities = 166/552 (30%), Positives = 243/552 (44%), Gaps = 64/552 (11%)
Query: 3 LLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPE 62
LL LL L +A+ R Q+ S + +PA L + ++ +TCG PE
Sbjct: 8 LLLLLLSGGLGGVQAQ-RPQQQRQSQAHQQRGLFPAV--LNLASNALITTNATCGEKGPE 64
Query: 63 PYC-IVSHLQ----EDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQS--- 114
YC +V H+ + +C ICN +P ++ I+ T WWQS
Sbjct: 65 MYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNT---------WWQSPSI 115
Query: 115 ENGVEN--VTIQLDLEAEFHFTHLIM-TFKTFRPAAMLIERSSDFG--KTWGVYRYFAYD 169
+NG+E VTI LDL+ F ++I+ + RP ++ERS D K W + +
Sbjct: 116 KNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTE 175
Query: 170 CEASF---PGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQN 226
C + P K D++IC S YS I P GE+ ++ +DP SP +
Sbjct: 176 CLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDP-SPELLE 234
Query: 227 LLKITNLRIKFVKLHTLG-DNLLDSRMEIRE-------KYYYAVYDMVVRGNCFCYGHAS 278
+R++F ++ TL D ++ + + RE +YYY+V D+ V G C CYGHA
Sbjct: 235 FTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHAR 294
Query: 279 ECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCN 338
C P+D + C C HNT G +C+ C +H PWR C+ CNC+
Sbjct: 295 AC-PLDPATNK------SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCH 347
Query: 339 EHSISCHFD-------MAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRD 391
+ C++D +++ + + GGVC +C NT G NCE C +++
Sbjct: 348 GKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNY 407
Query: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSED 451
P C+ C CDP GS NE GL G C CK G CD C G+
Sbjct: 408 PRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-- 465
Query: 452 PFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPC 510
CK+C C+ LG+ +PC G C CK V G C +C + L D GC C
Sbjct: 466 ---CKACNCSGLGS-KNEDPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518
Query: 511 DCDLGGALNNSC 522
C ++N C
Sbjct: 519 FC---SGVSNRC 527
Score = 171 bits (434), Expect = 4e-42
Identities = 99/291 (34%), Positives = 137/291 (47%), Gaps = 39/291 (13%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS-GCKPCECHLQGSVNA 831
C C+ GS S VC GQC+CR NV G+ C++C GTFG + GC PC C+ GS +
Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSF 977
Query: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDY 889
C +GQC C GV ++CDRC G++ F C C+C+ ++CDP TG C+ C
Sbjct: 978 DCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPN 1035
Query: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
T+G C +C +G I C+ C C Q + Q C C P
Sbjct: 1036 TIGEKCSKCAPNTWGHSITTG---CKACNCSTVGSLDFQCNVNTGQ--------CNCHPK 1084
Query: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRC--------LKCL 1001
+ G++C +C+ G++ P C C C + TD CD ET +C C
Sbjct: 1085 FSGAKCTECSRGHWNYPR-----CNLCDCF--LPGTDATTCDSETKKCSCSDQTGQCTCK 1137
Query: 1002 YHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
+ EG HC CR G +G D + N LG +C G+ QC +A G
Sbjct: 1138 VNVEGIHCDRCRPGKFG----LDAK----NPLGCSSCYCFGTTTQCSEAKG 1180
Score = 156 bits (394), Expect = 2e-37
Identities = 180/836 (21%), Positives = 312/836 (37%), Gaps = 164/836 (19%)
Query: 937 PVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG--------SCQPCQCHNNIDTTDPE 988
P L C C GY G C+ C G++ S+ GG +C PCQC+ +
Sbjct: 1373 PADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH-----SS 1427
Query: 989 ACDKETGRCLKCLYHTEGEHCQFCRFGYYG--DALQQDCRKCVCNYLGT---VQEHCNGS 1043
CD ET C C +HT G+ C+ C GYYG L DC++C C + + C
Sbjct: 1428 LCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE 1487
Query: 1044 DCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG--CDPCNCNAAHSFGPSCNEFTG 1101
+ T C GQ C+RCAP G C C C+ S C+ TG
Sbjct: 1488 GLDDYRCTA---CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTG 1544
Query: 1102 QCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR 1161
C C PG GR C C+ + EC C
Sbjct: 1545 FCTCRPGATGRKCDGCKH-WHAREGWECVFCG---------------------------- 1575
Query: 1162 CDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVD 1221
D+CT +++ +L R + ++ ++G + + +
Sbjct: 1576 -DECT--------------------GLLLGDLA----RLEQMVMSINLTGPLPAPYKMLY 1610
Query: 1222 SVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNST 1281
+E E+K +L+ A E L + AE + + M ++ + + T+ T
Sbjct: 1611 GLENMTQELKHLLSPQRAPE------RLIQLAEGNLNTLVTEMNELLTRATKVTADGEQT 1664
Query: 1282 AKELDSLQTEAESLDNTVKELAEQLEFIKNSDIR--GALDSITKYFQMSLEAEERVNAST 1339
++ + T A+SL +KELA E + I+ L + + F+ +LE ++
Sbjct: 1665 GQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQK----- 1719
Query: 1340 TEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCG 1399
++Q ++++ + KE E++ + L K++ L
Sbjct: 1720 -----EIDQ------MIKELRRKNLETQKEIAEDELVAAEALLKKVKKLF---------- 1758
Query: 1400 TPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVE 1459
G S E E + R + K N A DL ++ + E
Sbjct: 1759 ---GESRGENEEMEKDLREKLADYK--------------NKVDDAWDLLREATDKIREAN 1801
Query: 1460 QLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLD 1519
+L V++ + A E K KE ++ ++ N +K+ + L + + D
Sbjct: 1802 RLF-AVNQKNMTALEKK-------------KEAVESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 1520 SIEAVAN--EVLKMEMPSTPQQLQNLTEDI------RERVESLSQVEVILQHSAADIARA 1571
I ++ + E ++ ++P ++L + +D+ R+ E +SQ E A
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVL 1907
Query: 1572 EMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE 1631
+ +L+EAK S +AT +K+ ++EAEK A+ +A + G + LL
Sbjct: 1908 DGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLL---- 1963
Query: 1632 SETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLD 1691
+E Q+ + ++L +N ++ + D+ +TL+
Sbjct: 1964 ------KEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLN 2017
Query: 1692 GELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKY 1747
L K + N A K + D KA + AK +LAQ Q L L++ Y
Sbjct: 2018 DTLG-KLSAIPNDTAAKLQAVKD---KARQANDTAKDVLAQITELHQNLDGLKKNY 2069
Score = 145 bits (365), Expect = 4e-34
Identities = 104/373 (27%), Positives = 140/373 (37%), Gaps = 126/373 (33%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
C C+GHA C V G C+ C+ +T G C+ C+ ++ P +G S
Sbjct: 757 CQCFGHAESCDDVT-----------GECLNCKDHTGGPYCDKCLPGFYG---EPTKG-TS 801
Query: 330 NACKKCNC------NEHSISCHFDMAV----------------------YLATGNVSGGV 361
C+ C C N S +CH D ++ Y +V GG
Sbjct: 802 EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS 861
Query: 362 CDDCQHN------------------------TMGRNCEQCKPFYYQHPERDIRDPNFCER 397
C CQ N T GR CE C Y+ D D C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF----GDAVDAKNCQP 917
Query: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
C C+ GS +E +C S T GQC C+ NV+G+ CD CK G + L S GC
Sbjct: 918 CRCNAGGSFSE-VCHSQT--------GQCECRANVQGQRCDKCKAGTFGLQSAR--GCVP 966
Query: 458 CACNPLGT-------------IPG-----------------------------GNPCDSE 475
C CN G+ PG GN CD +
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPK 1026
Query: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
TG C C G+ C +C P WG S GC+ C+C G+L+ C +GQC+C P
Sbjct: 1027 TGRCICPPNTIGEKCSKCAPNTWGHS-ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKF 1085
Query: 536 IGRQCNEVEPGYY 548
G +C E G++
Sbjct: 1086 SGAKCTECSRGHW 1098
Score = 133 bits (334), Expect = 2e-30
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 18/188 (9%)
Query: 839 QCHCFQGVYARQCDRCLPGHWGFPS-------------CQPCQCNGHADDCDPVTGECLN 885
+C C G C+ CLPG + S C PCQCNGH+ CDP T C N
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 886 CQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
CQ +T G CERC GYYG + G + C+ C CP S F+ SC + +
Sbjct: 1439 CQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACP-LISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 946 CDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
C GY G C+ CA GY G+P GGSCQ C+C + + P CD TG C C
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECEC--DPYGSLPVPCDPVTGFC-TCRPGAT 1553
Query: 1006 GEHCQFCR 1013
G C C+
Sbjct: 1554 GRKCDGCK 1561
Score = 127 bits (319), Expect = 1e-28
Identities = 75/254 (29%), Positives = 119/254 (46%), Gaps = 24/254 (9%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C C G +CE C + + G C+ C C H+ SC D+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGG----ICEPCQCFGHAESCD-DVT-------- 770
Query: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
G C +C+ +T G C++C P +Y P + + C+ C C N + D
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFSPTCHLDR 826
Query: 418 STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPL--GTIPGGNPCDSE 475
S GLI C + G C+ C EG++ S C+ C CN +IPG CDS
Sbjct: 827 SLGLICDGC--PVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS--CDSL 882
Query: 476 TGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
+G C CK TG++C+ C ++G + D C+PC C+ GG+ + C +++GQC CR +
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 535 MIGRQCNEVEPGYY 548
+ G++C++ + G +
Sbjct: 943 VQGQRCDKCKAGTF 956
Score = 110 bits (274), Expect = 2e-23
Identities = 65/205 (31%), Positives = 93/205 (45%), Gaps = 25/205 (12%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPA---EGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
C C GL+CE C+ ++ L +P G C C CN HS C + ++
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI---- 1435
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
C +CQH+T G CE+C YY + PN C++C C S N S
Sbjct: 1436 -------CQNCQHHTAGDFCERCALGYYGIVKGL---PNDCQQCACPLISSSNNF---SP 1482
Query: 415 TDFSTGLIAGQCR-CKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
+ + GL +C C EG++C+ C G+ C+ C C+P G++P PCD
Sbjct: 1483 SCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPV--PCD 1540
Query: 474 SETGHCYCKRLVTGQHCDQCLPEHW 498
TG C C+ TG+ CD C +HW
Sbjct: 1541 PVTGFCTCRPGATGRKCDGC--KHW 1563
Score = 100 bits (249), Expect = 1e-20
Identities = 73/269 (27%), Positives = 103/269 (38%), Gaps = 57/269 (21%)
Query: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA 989
AR+C DP T + C C+ G CD C G+ P G +C EA
Sbjct: 293 ARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC---------EA 343
Query: 990 CDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDK 1049
C+ H + E C YY + + + R N G ++ G C
Sbjct: 344 CN----------CHGKAEEC------YYDENVAR--RNLSLNIRG---KYIGGGVC---- 378
Query: 1050 ATGQCLCLPNVIGQNCDRCAPNTWQLASGTG-----CDPCNCNAAHSFGPSCNE------ 1098
C N G NC+ C ++ + C PC+C+ S C +
Sbjct: 379 ----INCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHAR 434
Query: 1099 ---FTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVE 1155
G C C GFGG +C C + G PD C+AC+C G+ + D G C+C E
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYPD--CKACNCS--GLGSKNEDPCFGPCICKE 490
Query: 1156 GVEGPRCDKCTRGYSGVFPD-CTPCHQCF 1183
VEG C +C G+ + D C +CF
Sbjct: 491 NVEGGDCSRCKSGFFNLQEDNWKGCDECF 519
Score = 93.2 bits (230), Expect = 2e-18
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 35/241 (14%)
Query: 335 CNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPER--DIRDP 392
C C H+ +C D A + C+ C+HNT G +C+QC P ++Q P R
Sbjct: 287 CICYGHARACPLDPATNKSR-------CE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 393 NFCERCTCDPAGSQ---NEGICDSYTDFSTG---LIAGQC-RCKLNVEGEHCDVCKEGFY 445
CE C C + +E + + + G C C N G +C+ C +GF+
Sbjct: 339 TECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF 398
Query: 446 ---DLSSEDPFGCKSCACNPLGTIPGGNPCDSE-------TGHCYCKRLVTGQHCDQCLP 495
+S P C+ C C+P+G++ D + G C+CK G CD+C
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCAR 458
Query: 496 EHWGLSNDLDGCRPCDCD-LGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDH 554
+ G + C+ C+C LG + CF G C C+ ++ G C+ + G++ D+
Sbjct: 459 GYTGYPD----CKACNCSGLGSKNEDPCF---GPCICKENVEGGDCSRCKSGFFNLQEDN 511
Query: 555 Y 555
+
Sbjct: 512 W 512
Score = 93.2 bits (230), Expect = 2e-18
Identities = 84/305 (27%), Positives = 101/305 (33%), Gaps = 91/305 (29%)
Query: 277 ASECAP----VDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNAC 332
A C P G EV G C CR N +G C+ C L +++ C
Sbjct: 912 AKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL-------QSARGC 964
Query: 333 KKCNCNEH---SISCHFDMAVYLATGNVSGGVCDDCQH---------------------- 367
CNCN S C + G V+G CD C H
Sbjct: 965 VPCNCNSFGSKSFDCEESGQCWCQPG-VTGKKCDRCAHGYFNFQEGGCTACECSHLGNNC 1023
Query: 368 -----------NTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTD 416
NT+G C +C P + H C+ C C GS D
Sbjct: 1024 DPKTGRCICPPNTIGEKCSKCAPNTWGHSIT-----TGCKACNCSTVGS---------LD 1069
Query: 417 FSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSET 476
F + GQC C G C C G ++ C C C GT CDSET
Sbjct: 1070 FQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGT--DATTCDSET 1122
Query: 477 ---------GHCYCKRLVTGQHCDQCLPEHWGL--SNDLDGCRPCDCDLGGALNNSCFAE 525
G C CK V G HCD+C P +GL N L GC C CF
Sbjct: 1123 KKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPL-GCSSC----------YCFGT 1171
Query: 526 SGQCS 530
+ QCS
Sbjct: 1172 TTQCS 1176
Score = 89.7 bits (221), Expect = 2e-17
Identities = 78/278 (28%), Positives = 107/278 (38%), Gaps = 56/278 (20%)
Query: 867 CQCNGHADDC--DPVTGEC-LNCQDYTMGHNCERCLAGYYGDP----IIGSGDHCRPCPC 919
C C GHA C DP T + C+ T G +C++C G++ P + C C C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 920 PDGPDSGRQFARSCYQDP------VTLQL--------ACV-CDPGYIGSRCDDCASGYFG 964
G+ A CY D ++L + C+ C G C+ C G+F
Sbjct: 347 -----HGK--AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF- 398
Query: 965 NPSEVGGS----CQPCQCH-----NNIDTTDPEACDK--ETGRCLKCLYHTEGEHCQFCR 1013
P V + CQPC C N + D + + G C C G C C
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCA 457
Query: 1014 FGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTW 1073
GY G DC+ C C+ LG+ E D G C+C NV G +C RC +
Sbjct: 458 RGYTG---YPDCKACNCSGLGSKNE---------DPCFGPCICKENVEGGDCSRCKSGFF 505
Query: 1074 QLASGT--GCDPCNCNAAHSFGPSCNEFTGQCQCMPGF 1109
L GCD C C+ + S G+ Q M G+
Sbjct: 506 NLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Score = 87.4 bits (215), Expect = 1e-16
Identities = 78/291 (26%), Positives = 114/291 (39%), Gaps = 74/291 (25%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAP---------GTFGFGPSGCKPCE 822
AC DP N +C+C N G +C++C P GTF + C+ C
Sbjct: 295 ACPLDPA--------TNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF-LTKTECEACN 345
Query: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGE 882
CH + +C+ + V R + G + G G
Sbjct: 346 CHGKAE----------ECYYDENVARRNLSLNIRGKY---------IGG---------GV 377
Query: 883 CLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPC-PCPDGPDSGRQFARSCYQDPVTLQ 941
C+NC T G NCE C G++ P S ++ RPC PC P C +D +
Sbjct: 378 CINCTQNTAGINCETCTDGFF-RPKGVSPNYPRPCQPCHCDPIG--SLNEVCVKDEKHAR 434
Query: 942 L-----ACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGR 996
+C C G+ G CD CA GY G P C+ C C + + + + + C G
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYP-----DCKACNC-SGLGSKNEDPC---FGP 485
Query: 997 CLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGS 1043
C+ C + EG C C+ G++ LQ+D C +C C+ V C S
Sbjct: 486 CI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCDECFCS---GVSNRCQSS 530
Score = 86.7 bits (213), Expect = 2e-16
Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 22/189 (11%)
Query: 364 DCQHNTMGRNCEQCKPFYYQ---HPERDIRDPNF--CERCTCDPAGSQNEGICDSYTDFS 418
DC G +CE C P +Y+ P P C C C+ S +CD T
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS----LCDPETSIC 1436
Query: 419 TGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP-CDSETG 477
C+ + G+ C+ C G+Y + P C+ CAC + + +P C +E
Sbjct: 1437 QN-------CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGL 1489
Query: 478 HCY----CKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQCSCR 532
Y C R GQ+C++C P + G + G C+ C+CD G+L C +G C+CR
Sbjct: 1490 DDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549
Query: 533 PHMIGRQCN 541
P GR+C+
Sbjct: 1550 PGATGRKCD 1558
Score = 76.3 bits (186), Expect = 3e-13
Identities = 59/194 (30%), Positives = 74/194 (38%), Gaps = 38/194 (19%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFGF---------GPS--GCKPCECHLQGSVNAFCNPVTGQ 839
+C C G +C C PG + GP+ C PC+C+ S+ C+P T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 840 C-HCFQGVYARQCDRCLPGHWGF-----PSCQPCQC------NGHADDCDPV---TGECL 884
C +C C+RC G++G CQ C C N + C C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
C G CERC GY G P G C+ C C D C DPVT C
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSP-GNPGGSCQECEC----DPYGSLPVPC--DPVT--GFC 1546
Query: 945 VCDPGYIGSRCDDC 958
C PG G +CD C
Sbjct: 1547 TCRPGATGRKCDGC 1560
Score = 72.4 bits (176), Expect = 4e-12
Identities = 77/253 (30%), Positives = 104/253 (41%), Gaps = 49/253 (19%)
Query: 343 SCHFDMAV-YLATGNVSGGV--CDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNF---CE 396
S + + AV Y G+++ V C C G +CE C P + R + F CE
Sbjct: 702 SVNLESAVSYPTDGSIAAAVEVCQ-CPPGYTGSSCESCWPRH-----RRVNGTIFGGICE 755
Query: 397 RCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDL----SSED 451
C C CD T G+C CK + G +CD C GFY +SED
Sbjct: 756 PCQCFGHAES----CDDVT--------GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED 803
Query: 452 PFGCKSCACNPLGTIPGGNPCDSETGHCY---------CKRLVTGQHCDQCLPEHWGLSN 502
C+ CAC PL IP N S T H C TG C++C ++G +
Sbjct: 804 ---CQPCAC-PLN-IPSNN--FSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856
Query: 503 DLDG-CRPCDCD--LGGALNNSCFAESGQCS-CRPHMIGRQCNEVEPGYYFATLDHYLYE 558
G C+PC C+ L ++ SC + SG C C+P GR C GY+ +D +
Sbjct: 857 VPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQ 916
Query: 559 AEEANLGPGVSIV 571
N G S V
Sbjct: 917 PCRCNAGGSFSEV 929
Score = 66.6 bits (161), Expect = 2e-10
Identities = 52/172 (30%), Positives = 69/172 (40%), Gaps = 31/172 (18%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELC-MDFYHDLPWRPAEGRNS 329
C C GH+S C P + C+H+T G CE C + +Y + P
Sbjct: 1420 CQCNGHSSLCDPETSICQN----------CQHHTAGDFCERCALGYYGIVKGLP------ 1463
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
N C++C C S S +F + +A G + C C G+ CE+C P Y P
Sbjct: 1464 NDCQQCACPLISSSNNFSPSC-VAEG-LDDYRCTACPRGYEGQYCERCAPGYTGSPG--- 1518
Query: 390 RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCK 441
C+ C CDP GS CD T F C C+ G CD CK
Sbjct: 1519 NPGGSCQECECDPYGSLPVP-CDPVTGF--------CTCRPGATGRKCDGCK 1561
Score = 64.3 bits (155), Expect = 1e-09
Identities = 45/141 (31%), Positives = 62/141 (43%), Gaps = 24/141 (17%)
Query: 425 QCRCKLNVEGEHCDVCKEGFYDLSSEDPFG---------CKSCACNPLGTIPGGNPCDSE 475
+C C L G C+ C GFY L S+ P G C C CN ++ CD E
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQ-PGGRTPGPTLGTCVPCQCNGHSSL-----CDPE 1432
Query: 476 TGHCY-CKRLVTGQHCDQCLPEHWGLSNDL-DGCRPCDCDLGGALNN---SCFAE---SG 527
T C C+ G C++C ++G+ L + C+ C C L + NN SC AE
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 528 QCSCRPH-MIGRQCNEVEPGY 547
+C+ P G+ C PGY
Sbjct: 1493 RCTACPRGYEGQYCERCAPGY 1513
Score = 60.1 bits (144), Expect = 2e-08
Identities = 31/69 (44%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Query: 794 CRPNVVGRTCNRCAPGTFGF--GPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQ 850
C G+ C RCAPG G P G C+ CEC GS+ C+PVTG C C G R+
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 851 CDRCLPGHW 859
CD C HW
Sbjct: 1557 CDGC--KHW 1563
Score = 52.4 bits (124), Expect = 4e-06
Identities = 39/121 (32%), Positives = 48/121 (39%), Gaps = 16/121 (13%)
Query: 710 CKSLDIFTVGGSGDGVVTNSAW----ETFQRYRCLENSRSVVKTPMTDVCRNIIFSISAL 765
CK+ + TVG N+ F +C E SR P ++C
Sbjct: 1057 CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLC-------DCF 1109
Query: 766 LHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCKPCE 822
L T A CD + S C GQC C+ NV G C+RC PG FG P GC C
Sbjct: 1110 LPGTD-ATTCDSETKKCS-CSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 823 C 823
C
Sbjct: 1168 C 1168
Score = 50.8 bits (120), Expect = 1e-05
Identities = 20/34 (58%), Positives = 21/34 (61%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRC 806
CECDP GSL CDP G C CRP GR C+ C
Sbjct: 1527 CECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831
AC C GS + DP G C C+ NV G C+RC G F K C+
Sbjct: 468 ACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD-------EC 518
Query: 832 FCNPVTGQCHCFQGVYAR 849
FC+ V+ +C Y +
Sbjct: 519 FCSGVSNRCQSSYWTYGK 536
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 291 bits (746), Expect = 3e-78
Identities = 141/350 (40%), Positives = 191/350 (54%), Gaps = 22/350 (6%)
Query: 840 CHCFQGVYARQCDRCLPGHWGFPS------CQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
C C QG C+ CL G++ CQPC+C+GHA +C+ V G C+ C T G
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECN-VHGVCIACAHNTTGV 767
Query: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGS 953
+CE+CL G+YG+P G+ C+PC CP S F+ +C+ + + C PGY G+
Sbjct: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNN-FSPTCHLNDGDEVVCDWCAPGYSGA 826
Query: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCR 1013
C+ CA GY+GNP+ G SC PC C N+D ++ CD TG CLKCL +T+G HC+ C
Sbjct: 827 WCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCA 886
Query: 1014 FGYYGDAL-QQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNT 1072
G+YGDA+ ++CR C C+ G+ C TG C C PNV GQ CD+C
Sbjct: 887 DGFYGDAVTAKNCRACECHVKGS-------HSAVCHLETGLCDCKPNVTGQQCDQCLHGY 939
Query: 1073 WQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRAC 1132
+ L SG GC PCNC+ A S C + GQC C+PG G+ C C F+ D C C
Sbjct: 940 YGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
Query: 1133 DCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD--CTPCH 1180
DC P T CD TG+CVC +G +C++C G+ G + C C+
Sbjct: 999 DC-PHTQNT--CDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACN 1045
Score = 266 bits (679), Expect = 2e-70
Identities = 227/862 (26%), Positives = 352/862 (40%), Gaps = 167/862 (19%)
Query: 425 QCRCKLNVEGEHCDVCKEGFYD-------LSSEDPFGCKSCAC----------------- 460
QC+C+ N GE C+ C G++ +SS + C++C C
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNT--CEACNCHNKAKDCYYDESVAKQK 346
Query: 461 ---NPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN----DLDGCRPCDCD 513
N G GG C + C + G +C+ C+ ++ + + CRPC+CD
Sbjct: 347 KSLNTAGQFRGGGVCIN------CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCD 400
Query: 514 LGGALNNSCFAES-----------GQCSCRPHMIGRQCNEVEPGY------YFATLDHYL 556
G+L++ C + GQC C+ G +C+ + GY +
Sbjct: 401 PVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVG 460
Query: 557 YEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPE------GAYLEFFIDNIPYSMEY 610
++E GP V ++ ++ + GF + E F + ++ S+ +
Sbjct: 461 SASDEPCTGPCVC---KENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSW 517
Query: 611 DILIRYEPQLPDHWEKAVITVQRPGRIPTSSRC---GNTIPDDDNQVVSLSPGSRYVVLP 667
+ Q+ V + P +IP+ + + ++ V+ Y P
Sbjct: 518 PV-----GQVNSMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAP 572
Query: 668 RPVCFEKGT------NYTVRLELPQYTSSDSDVESPYTLI------------DSLVLMPY 709
K T YTV ++P T DS++ S +I + L L PY
Sbjct: 573 EAYLGNKLTAFGGFLKYTVSYDIPVETV-DSNLMSHADVIIKGNGLTLSTQAEGLSLQPY 631
Query: 710 CKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSI------- 762
+ L++ + E FQ + + R + + + V N+ +
Sbjct: 632 EEYLNVVRL-----------VPENFQDFH---SKRQIDRDQLMTVLANVTHLLIRANYNS 677
Query: 763 --SALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG-----FGP 815
AL ++ + ++ V + C+C G +C C G + FG
Sbjct: 678 AKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGG 737
Query: 816 SGCKPCECHLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFPS------CQPCQ 868
C+PCECH A CN V G C C C++CLPG +G PS CQPC
Sbjct: 738 I-CQPCECHGHA---AECN-VHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCA 792
Query: 869 C------NGHADDCDPVTGECLNCQDYTMGHN---CERCLAGYYGDPIIGSGDHCRPCPC 919
C N + C G+ + C G++ CERC GYYG+P + G+ C PC C
Sbjct: 793 CPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTV-PGESCVPCDC 851
Query: 920 PDGPDSGRQFARSCYQDPVTLQ-LACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
D A C D VT + L C+ + G+ C+ CA G++G+ + +C+ C+C
Sbjct: 852 SGNVDPSE--AGHC--DSVTGECLKCLGNTD--GAHCERCADGFYGD-AVTAKNCRACEC 904
Query: 979 HNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQE 1038
H + + C ETG C C + G+ C C GYYG CR C C+ G+V +
Sbjct: 905 H--VKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSD 961
Query: 1039 HCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNE 1098
C GQC C+P V G+ CDRCA + G+ C PC+C + +C+
Sbjct: 962 GCTDE--------GQCHCVPGVAGKRCDRCAHGFYAYQDGS-CTPCDCPHTQN---TCDP 1009
Query: 1099 FTGQCQCMPGFGGRTCSECQELFWG-DPDVECRACDCDPRGIETPQCDQSTGQCVCVEGV 1157
TG+C C P G C EC++ WG D +V C+AC+C G +CD TG C C
Sbjct: 1010 ETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKF 1069
Query: 1158 EGPRCDKCTRGYSGVFPDCTPC 1179
G CD+C+ GY FPDC PC
Sbjct: 1070 GGRACDQCSLGYRD-FPDCVPC 1090
Score = 253 bits (645), Expect = 2e-66
Identities = 193/624 (30%), Positives = 281/624 (45%), Gaps = 86/624 (13%)
Query: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYC-IVSHLQ----EDKKCFICNSQDP 84
C + +PA L + +S +TCG PE +C +V H+ + +C IC+
Sbjct: 17 CRQRGLFPAI--LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSA 74
Query: 85 YHETLNPDSHLIENVVTTFAPNRLKIWWQS---ENGVEN--VTIQLDLEAEFHFTHLIMT 139
+P SH I+ WWQS +NG E VTI LDL F ++I+
Sbjct: 75 NPRERHPISHAIDGTNN---------WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
Query: 140 FKTF-RPAAMLIERSSDFGKTWGVYRYFAY---DCEASF---PGISTGPMKKVDDIICDS 192
RP ++ERS D G T+ ++Y+A +C + + P + D++IC S
Sbjct: 126 AANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTS 184
Query: 193 RYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLD-SR 251
YS + P GE I +L D SP++ +R++ ++ TL +L+ S
Sbjct: 185 YYSRLVPLEHGE-IHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMTLSH 243
Query: 252 MEIRE-------KYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNT 304
E +E +YYY++ D+ V G C CYGHAS C P D ++++ C C HNT
Sbjct: 244 REPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC-PWDETTKKLQ------CQCEHNT 296
Query: 305 KGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVS------ 358
G +C C YH PWRP + N C+ CNC+ + C++D +V +++
Sbjct: 297 CGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFR 356
Query: 359 -GGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC---DSY 414
GGVC +C NTMG NCE C YY+ + + C C CDP GS + +C D +
Sbjct: 357 GGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLS-SVCIKDDLH 415
Query: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
+D G GQC CK GE CD C+ G+ D + C SC CNP+G+ PC
Sbjct: 416 SDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT-----CVSCGCNPVGS-ASDEPC-- 467
Query: 475 ETGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
TG C CK V G+ CD+C P + L + GC C CF S CS
Sbjct: 468 -TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC----------FCFGVSDVCSSLS 516
Query: 534 HMIGRQCNEVEPGYYFATLDHYLYEAEEANLG--PGVSIVERQYIQDRIPSWTGAGFVRV 591
+G Q N + + +++ LG VSI +Q P + A
Sbjct: 517 WPVG-QVNSMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWA----A 571
Query: 592 PE---GAYLEFFIDNIPYSMEYDI 612
PE G L F + Y++ YDI
Sbjct: 572 PEAYLGNKLTAFGGFLKYTVSYDI 595
Score = 168 bits (425), Expect = 5e-41
Identities = 99/278 (35%), Positives = 132/278 (47%), Gaps = 39/278 (14%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS-GCKPCECHLQGSVN 830
ACEC +GS S+VC G C C+PNV G+ C++C G +G GC+PC C + GSV+
Sbjct: 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS 960
Query: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP--SCQPCQCNGHADDCDPVTGECLNCQD 888
C GQCHC GV ++CDRC G + + SC PC C + CDP TGEC+ C
Sbjct: 961 DGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPP 1018
Query: 889 YTMGHNCERCLAGYYG-DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
+T G CE C G++G D +G C+ C C S + + C C
Sbjct: 1019 HTQGVKCEECEDGHWGYDAEVG----CQACNC--------SLVGSTHHRCDVVTGHCQCK 1066
Query: 948 PGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRC--------LK 999
+ G CD C+ GY P C PC C ++ T +AC+ E G C
Sbjct: 1067 SKFGGRACDQCSLGYRDFP-----DCVPCDC--DLRGTSGDACNLEQGLCGCVEETGACP 1119
Query: 1000 CLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYL 1033
C + G C CR G + AL+ D C C C+ L
Sbjct: 1120 CKENVFGPQCNECREGTF--ALRADNPLGCSPCFCSGL 1155
Score = 164 bits (416), Expect = 5e-40
Identities = 103/296 (34%), Positives = 145/296 (48%), Gaps = 40/296 (13%)
Query: 259 YYAVYDMVVRG---NCFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMD 314
YY V ++ G C C+GHA+EC VHG C+ C HNT G++CE C+
Sbjct: 727 YYRVDGILFGGICQPCECHGHAAECN------------VHGVCIACAHNTTGVHCEQCLP 774
Query: 315 FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNC 374
++ P R G C+ C C S +F +L G+ VCD C G C
Sbjct: 775 GFYGEPSRGTPGD----CQPCACPLTIASNNFSPTCHLNDGDEV--VCDWCAPGYSGAWC 828
Query: 375 EQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDSYTDFSTGLIAGQC-RCKLNV 432
E+C YY +P C C C +E G CDS T G+C +C N
Sbjct: 829 ERCADGYYGNPTVPGES---CVPCDCSGNVDPSEAGHCDSVT--------GECLKCLGNT 877
Query: 433 EGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ 492
+G HC+ C +GFY + C++C C+ G+ C ETG C CK VTGQ CDQ
Sbjct: 878 DGAHCERCADGFYG-DAVTAKNCRACECHVKGSHSA--VCHLETGLCDCKPNVTGQQCDQ 934
Query: 493 CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
CL ++GL + GCRPC+C + G++++ C + GQC C P + G++C+ G+Y
Sbjct: 935 CLHGYYGLDSG-HGCRPCNCSVAGSVSDGC-TDEGQCHCVPGVAGKRCDRCAHGFY 988
Score = 141 bits (356), Expect = 5e-33
Identities = 84/279 (30%), Positives = 118/279 (42%), Gaps = 54/279 (19%)
Query: 280 CAPVDGFNEEVEGMVHGHC--------MCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNA 331
C P D + V+ GHC C NT G +CE C D ++ + +
Sbjct: 846 CVPCD-CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFY------GDAVTAKN 898
Query: 332 CKKCNCN---EHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
C+ C C+ HS CH + G+CD C+ N G+ C+QC YY
Sbjct: 899 CRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHGYY-----G 941
Query: 389 IRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLS 448
+ + C C C AGS ++G D GQC C V G+ CD C GFY
Sbjct: 942 LDSGHGCRPCNCSVAGSVSDGCTDE----------GQCHCVPGVAGKRCDRCAHGFY--- 988
Query: 449 SEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCR 508
+ +C P N CD ETG C C G C++C HWG ++ GC+
Sbjct: 989 -----AYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQ 1042
Query: 509 PCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGY 547
C+C L G+ ++ C +G C C+ GR C++ GY
Sbjct: 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY 1081
Score = 138 bits (347), Expect = 5e-32
Identities = 172/795 (21%), Positives = 308/795 (38%), Gaps = 94/795 (11%)
Query: 1000 CLYHTEGEHCQFCRFGYYGDALQQD-----------CRKCVCNYLGTVQEHCNGSDCQCD 1048
C T G CQ C GY+ L C C CN N SD CD
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---------NHSDT-CD 1413
Query: 1049 KATGQCL-CLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHS----FGPSC---NEFT 1100
TG+CL C N G +CD C + +G+ D C HS F P+C +
Sbjct: 1414 PNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHD 1473
Query: 1101 GQCQ-CMPGFGGRTCSECQELFWGDPDV---ECRACDCDPRGIETPQCDQSTGQCVCVEG 1156
+C C+ G+ G+ C C ++G+P C+ CDC+P G CD+++GQCVC G
Sbjct: 1474 FRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLG 1533
Query: 1157 VEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPY 1216
G RCD+C + + DC C D + L N + +L ++G+I
Sbjct: 1534 ASGLRCDECEPRHILMETDCVSCD------DECVGVLLNDLDEIGDAVLSLNLTGIIPVP 1587
Query: 1217 RETVDSVERKVSEIKDILAQSPAAEPLKNI--GNLFEEAEKLIKDVTEMMAQVEVKLSDT 1274
+ ++E +++ L + + L I + EE + L K +T M+A + K++
Sbjct: 1588 YGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQ-KVNRA 1646
Query: 1275 TSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSD-----IRGALDSITKYFQMSL 1329
T + KE L E L ++ E+ E+ + D L ++ + L
Sbjct: 1647 TER---IFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLL 1703
Query: 1330 EAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSL- 1388
E + + + N+T+E A ED++ + + + +K E+ +L E A + S
Sbjct: 1704 EIMQIRDFTQLHQNATLELKA-----AEDLLSQIQENY-QKPLEELEVLKEAASHVLSKH 1757
Query: 1389 --DLSAAAEMTCGTPPG----------ASCSETECGGPNCRTDEGERKCGGPGCGGLVTV 1436
+L AA + + + E E + G +
Sbjct: 1758 NNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLI 1817
Query: 1437 AHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLR-------ADEAKQSAEDILLKTNAT 1489
A Q D QD L L E Q ++ AK+R ++++A D++ +
Sbjct: 1818 DAAAAQ--TDAVQDALEHL-EDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDH 1874
Query: 1490 KEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRE 1549
+ + + L + ++ IRN S+ A + + + S ++ + L D
Sbjct: 1875 AAEFQRLADVLYSGLENIRNV---------SLNATSAAYVHYNIQSLIEESEELARDAHR 1925
Query: 1550 RVESLSQV-EVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVA 1608
V S + E ++ + A + R+ L+E S+ + + + E + + Q
Sbjct: 1926 TVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE---LSELRNKTNRFQEN 1982
Query: 1609 AEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGE 1668
A + +Q +E + + + I + A ++E +ASQ R+V L ++ S
Sbjct: 1983 AVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSAS 2042
Query: 1669 AEYIEKVVYTVKQSAED--VKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEA 1726
+ + Q +D + L G + + NL+ + + +E
Sbjct: 2043 LSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEI 2102
Query: 1727 KTLLAQANSKLQLLK 1741
K L++QA + +K
Sbjct: 2103 KLLISQARKQAASIK 2117
Score = 134 bits (336), Expect = 1e-30
Identities = 73/205 (35%), Positives = 95/205 (46%), Gaps = 26/205 (12%)
Query: 840 CHCFQGVYARQCDRCLPG-HWG-------------FPSCQPCQCNGHADDCDPVTGECLN 885
C C G C C PG H G C PC CN H+D CDP TG+CLN
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 886 CQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
C D T G +C+ C +GYYG + GS C C CP P + F+ +C +
Sbjct: 1422 CGDNTAGDHCDVCTSGYYG-KVTGSASDCALCACPHSPPA--SFSPTCVLEGDHDFRCDA 1478
Query: 946 CDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC--HNNIDTTDPEACDKETGRCLKCLYH 1003
C GY G C+ C+S Y+GNP GGSCQ C C H ++ CD+ +G+C+ C
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD----CDRTSGQCV-CRLG 1533
Query: 1004 TEGEHCQFCRFGYYGDALQQDCRKC 1028
G C C + ++ DC C
Sbjct: 1534 ASGLRCDECEPRHI--LMETDCVSC 1556
Score = 133 bits (335), Expect = 1e-30
Identities = 73/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 297 HCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGN 356
HC C G +CE C+ Y+ + G C+ C C+ H+ C+
Sbjct: 708 HCECPQGYTGTSCESCLSGYYRVDGILFGG----ICQPCECHGHAAECNVH--------- 754
Query: 357 VSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTD 416
GVC C HNT G +CEQC P +Y P R P C+ C C + N + +
Sbjct: 755 ---GVCIACAHNTTGVHCEQCLPGFYGEPSRGT--PGDCQPCACPLTIASNNFSPTCHLN 809
Query: 417 FSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSET 476
++ C G C+ C +G+Y + C C C+ CDS T
Sbjct: 810 DGDEVVCDWCAP--GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVT 867
Query: 477 GHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
G C C G HC++C +G + CR C+C + G+ + C E+G C C+P++
Sbjct: 868 GECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNV 927
Query: 536 IGRQCNEVEPGYY 548
G+QC++ GYY
Sbjct: 928 TGQQCDQCLHGYY 940
Score = 109 bits (272), Expect = 3e-23
Identities = 72/240 (30%), Positives = 99/240 (41%), Gaps = 33/240 (13%)
Query: 288 EEVEGMVHGHCMCRHNTKGLNCELCMDFYH--DLPWRPAEGRNS--NACKKCNCNEHSIS 343
EEV ++ +C+C T G +C+ C YH LP G C C+CN HS +
Sbjct: 1353 EEVASLLE-NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT 1411
Query: 344 CHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC--- 400
C + + G C +C NT G +C+ C YY D C C C
Sbjct: 1412 C-----------DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD---CALCACPHS 1457
Query: 401 DPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCAC 460
PA + + DF C L EG+HC+ C +Y C+ C C
Sbjct: 1458 PPASFSPTCVLEGDHDFRCD------ACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDC 1511
Query: 461 NPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNN 520
NP G++ G CD +G C C+ +G CD+C P H + D C CD + G L N
Sbjct: 1512 NPHGSVHG--DCDRTSGQCVCRLGASGLRCDECEPRHILMETD---CVSCDDECVGVLLN 1566
Score = 104 bits (259), Expect = 9e-22
Identities = 68/230 (29%), Positives = 90/230 (39%), Gaps = 32/230 (13%)
Query: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQCHNNI-D 983
A SC D T +L C C+ G C+ C GY P G +C+ C CHN D
Sbjct: 276 ASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKD 335
Query: 984 TTDPEACDKET------------GRCLKCLYHTEGEHCQFCRFGYY-----GDALQQDCR 1026
E+ K+ G C+ CL +T G +C+ C GYY + CR
Sbjct: 336 CYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCR 395
Query: 1027 KCVCNYLGTVQEHCNGSDCQCD----KATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCD 1082
C C+ +G++ C D D K GQC C G+ CDRC + C
Sbjct: 396 PCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT---CV 452
Query: 1083 PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRAC 1132
C CN S S TG C C G+ C C+ F+ + R C
Sbjct: 453 SCGCNPVGS--ASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
Score = 99.0 bits (245), Expect = 4e-20
Identities = 70/242 (28%), Positives = 101/242 (41%), Gaps = 28/242 (11%)
Query: 365 CQHNTMGRNCEQCKPFYYQH--PERDIRDPNF----CERCTCDPAGSQNEGICDSYTDFS 418
C T+G +C+ C P Y++ P R P C C+C+ + CD T
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN----NHSDTCDPNT--- 1416
Query: 419 TGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETG 477
G+C C N G+HCDVC G+Y + C CAC C E
Sbjct: 1417 -----GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGD 1471
Query: 478 HCY----CKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQCSCR 532
H + C G+HC++C ++G G C+ CDC+ G+++ C SGQC CR
Sbjct: 1472 HDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCR 1531
Query: 533 PHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVP 592
G +C+E EP + D + E GV + + I D + S G + VP
Sbjct: 1532 LGASGLRCDECEPRHILMETDCVSCDDECV----GVLLNDLDEIGDAVLSLNLTGIIPVP 1587
Query: 593 EG 594
G
Sbjct: 1588 YG 1589
Score = 79.3 bits (194), Expect = 3e-14
Identities = 52/175 (29%), Positives = 77/175 (44%), Gaps = 38/175 (21%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNA-CKKCNCNEHSISCHFDMAVYLAT 354
G C+C +T+G+ CE C D + W G ++ C+ CNC+ + H
Sbjct: 1012 GECVCPPHTQGVKCEECEDGH----W----GYDAEVGCQACNCSLVGSTHH--------R 1055
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE------ 408
+V G C C+ GR C+QC Y P+ C C CD G+ +
Sbjct: 1056 CDVVTGHCQ-CKSKFGGRACDQCSLGYRDFPD--------CVPCDCDLRGTSGDACNLEQ 1106
Query: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPL 463
G+C + G C CK NV G C+ C+EG + L +++P GC C C+ L
Sbjct: 1107 GLCGCVEE------TGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGL 1155
Score = 79.0 bits (193), Expect = 4e-14
Identities = 59/194 (30%), Positives = 76/194 (39%), Gaps = 40/194 (20%)
Query: 792 CQCRPNVVGRTCNRCAPGTF-GFGPSG-----------CKPCECHLQGSVNAFCNPVTGQ 839
C C P VG +C CAPG G P+G C PC C+ C+P TG+
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT---CDPNTGK 1418
Query: 840 C-HCFQGVYARQCDRCLPGHWG-----FPSCQPCQC-----NGHADDCDPVTGECLNCQD 888
C +C CD C G++G C C C + C C
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 889 YTMGH---NCERCLAGYYGDPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLAC 944
+G+ +CERC + YYG+P G C+ C C P G S + D C
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGS-CQKCDCNPHG---------SVHGDCDRTSGQC 1528
Query: 945 VCDPGYIGSRCDDC 958
VC G G RCD+C
Sbjct: 1529 VCRLGASGLRCDEC 1542
Score = 71.6 bits (174), Expect = 6e-12
Identities = 46/150 (30%), Positives = 62/150 (41%), Gaps = 34/150 (22%)
Query: 773 CECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECH---- 824
C C+ S CDPN G+C C N G C+ C G +G S C C C
Sbjct: 1403 CSCNNH---SDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPP 1459
Query: 825 --------LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNG 871
L+G + C+ C G + C+RC ++G P SCQ C CN
Sbjct: 1460 ASFSPTCVLEGDHDFRCDA------CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNP 1513
Query: 872 HAD---DCDPVTGECLNCQDYTMGHNCERC 898
H DCD +G+C+ C+ G C+ C
Sbjct: 1514 HGSVHGDCDRTSGQCV-CRLGASGLRCDEC 1542
Score = 70.9 bits (172), Expect = 1e-11
Identities = 55/197 (27%), Positives = 80/197 (40%), Gaps = 36/197 (18%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
C C H+ C P G C+ C NT G +C++C Y+ G S
Sbjct: 1403 CSCNNHSDTCDPNTG-----------KCLNCGDNTAGDHCDVCTSGYYG----KVTGSAS 1447
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
+ C C C HS F L + CD C G++CE+C YY +P+
Sbjct: 1448 D-CALCAC-PHSPPASFSPTCVLEGDHDFR--CDACLLGYEGKHCERCSSSYYGNPQ--- 1500
Query: 390 RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSS 449
C++C C+P GS + G CD +GQC C+L G CD C+ + +
Sbjct: 1501 TPGGSCQKCDCNPHGSVH-GDCDR--------TSGQCVCRLGASGLRCDECEPRHILMET 1551
Query: 450 EDPFGCKSCACNPLGTI 466
+ C SC +G +
Sbjct: 1552 D----CVSCDDECVGVL 1564
Score = 58.5 bits (140), Expect = 6e-08
Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 772 ACECDPQGSLSSVCDPNGG---QCQ-CRPNVVGRTCNRCAPGTFGFG--PSG-CKPCECH 824
AC P S S C G +C C G+ C RC+ +G P G C+ C+C+
Sbjct: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCN 1512
Query: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
GSV+ C+ +GQC C G +CD C P H
Sbjct: 1513 PHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 283 bits (725), Expect = 8e-76
Identities = 159/478 (33%), Positives = 233/478 (48%), Gaps = 65/478 (13%)
Query: 111 WWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLIERSSDFGKTWGVYR 164
WWQS G+E V + LDL FH ++++ F RP ++ERS DFG+T+ ++
Sbjct: 127 WWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQ 186
Query: 165 YFAY---DCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPA-FKIEDPY 220
+FA DC F + + + D IC + YS I P GE++ ++ + Y
Sbjct: 187 FFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSY 246
Query: 221 SPRIQNLLKITNLRIKFVKLHTLGDNLLDSRME---IREKYYYAVYDMVVRGNCFCYGHA 277
SP ++ K TN+R++F++ +TL +L+ + + +YYY++ D+ + G C C+GHA
Sbjct: 247 SPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHA 306
Query: 278 SECA---PVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK 334
C P D F + C C+HNT G C+ C ++ PW+PA ++N C+
Sbjct: 307 DACDAKDPTDPFRLQ--------CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 335 CNCNEHSISCHFDMAVYLATGNVS-------GGVCDDCQHNTMGRNCEQCKPFYYQHPER 387
CNC H+ C++D V + S GGVC DCQH+T G NCE+C P +Y+ P
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 388 DIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
+ P+ C RC C+ +G C+ T G+C C+ N GE CDVC EGF
Sbjct: 419 PLDSPHVCRRCNCE--SDFTDGTCEDLT--------GRCYCRPNFSGERCDVCAEGFTGF 468
Query: 448 SSEDPFGCKS---------------CACNPLGTIPGGNPC--DSETGHCYCKRLVTGQHC 490
S P S C C+ GT GN C D G C CK G HC
Sbjct: 469 PSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGT--QGNACRKDPRVGRCLCKPNFQGTHC 526
Query: 491 DQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
+ C P +G GC+PC C G ++ C ++GQC CR G C+ PGY+
Sbjct: 527 ELCAPGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYF 579
Score = 279 bits (714), Expect = 2e-74
Identities = 259/982 (26%), Positives = 390/982 (39%), Gaps = 152/982 (15%)
Query: 840 CHCFQGVYARQCDRCLPGHWG------FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
C C C C PG + C PCQC+GH+D C P +G C++CQ T G
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGA 1890
Query: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGS 953
+CERC AG+ S C CPCP S FA C Q C+C PGY G+
Sbjct: 1891 HCERCQAGFVSSRDDPSAP-CVSCPCPLSVPSNN-FAEGCVLRGGRTQ--CLCKPGYAGA 1946
Query: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA----CDKETGRCLKCLYHTEGEHC 1009
C+ CA G+FGNP +G SCQPC C N DP CD TG C CL HT G C
Sbjct: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGN---GDPNLLFSDCDPLTGACRGCLRHTTGPRC 2003
Query: 1010 QFCRFGYYGDA-LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 1068
+ C G+YG+A L +C +C C GT CD +G CLC V G+ CDRC
Sbjct: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTE---------ACDPHSGHCLCKAGVTGRRCDRC 2054
Query: 1069 APNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE 1128
+ GC PC C A + G C+ +GQC C PG G C EC +WG P+
Sbjct: 2055 QEGHFGFDGCGGCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQG 2113
Query: 1129 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFP--------DCTPCH 1180
CR C C P G +CD TG+C C G+ G RCD C++ + P C C
Sbjct: 2114 CRRCQC-PGG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCD 2168
Query: 1181 QCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAA 1240
C L +D +ER + + I
Sbjct: 2169 HCVVL---------------------------------LLDDLERAGALLPAI------H 2189
Query: 1241 EPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVK 1300
E L+ I N A + + +A ++ +L + TA++L+ L+ ++ SL +
Sbjct: 2190 EQLRGI-NASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDAR 2248
Query: 1301 ELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVM 1360
L Q G D ++ + TE ++ L R D
Sbjct: 2249 RLGGQAV--------GTRDQASQLL------------AGTEATLGHAKTLLAAIRAVD-- 2286
Query: 1361 MERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDE 1420
R L EL + L L+ A+ P G T +
Sbjct: 2287 ---------------RTLSELMSQTGHLGLANAS-----APSGEQLLRTLAEVERLLWEM 2326
Query: 1421 GERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEA--KQS 1478
R G P +A A Q+ + Q+ LS+L E Q + +L EA
Sbjct: 2327 RARDLGAPQAAAEAELA--AAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDL 2384
Query: 1479 AEDILLKTNATKE--KMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVL------- 1529
E + +AT+E +++ N+E Q + L++D+A L + A + L
Sbjct: 2385 REALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLL 2444
Query: 1530 ------KMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK 1583
K E+ L + +R+++ S L+ A A A+ L + A S
Sbjct: 2445 HSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSS 2504
Query: 1584 SATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFN 1643
D V D + + EA A +A+ QA ED G Q L + + + L +
Sbjct: 2505 IILD--VNQDRLTQRAIEASNAYSRILQAV-QAAEDAAG-QALQQADHTWATVVRQGLVD 2560
Query: 1644 ASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVEN 1703
+Q++ +EE + Q G + + + DV+ D +L+ + +
Sbjct: 2561 RAQQLLANSTALEEAMLQEQQRLG---LVWAALQGARTQLRDVRAKKD-QLEAHIQAAQA 2616
Query: 1704 LIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYEDNQRYL--EDKAQEL 1761
++A T+E++ A+ + EA+ + S+LQ +++ +++ L +D Q +
Sbjct: 2617 MLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAV 2676
Query: 1762 ARLEGEVRSLLKDISQKVAVYS 1783
V +L K + Q +A S
Sbjct: 2677 LDAGHSVSTLEKTLPQLLAKLS 2698
Score = 240 bits (613), Expect = 8e-63
Identities = 139/409 (33%), Positives = 189/409 (46%), Gaps = 48/409 (11%)
Query: 773 CECDPQGSLSSVC--DPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
C+C G+ + C DP G+C C+PN G C CAPG +G GC+PC+C G +
Sbjct: 494 CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGVAD 550
Query: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHA---DDCDPVTGECLNCQ 887
C+P TGQC C G CDRC PG++ FP CQ C C+ + CD G CL CQ
Sbjct: 551 DRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDE-AGRCL-CQ 608
Query: 888 DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
G +C+RC GY+G P +C+ C C D + C + C C
Sbjct: 609 PEFAGPHCDRCRPGYHGFP------NCQACTC----DPRGALDQLCGAGGL-----CRCR 653
Query: 948 PGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGE 1007
PGY G+ C +C+ G+ G P SC PC C + + + ACD +G+C C G
Sbjct: 654 PGYTGTACQECSPGFHGFP-----SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVTGL 705
Query: 1008 HCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR 1067
C C G Y C C+ G D +A C+C +V G +CDR
Sbjct: 706 RCDTCVPGAYNFPY---CEAGSCHPAGLAP-----VDPALPEAQVPCMCRAHVEGPSCDR 757
Query: 1068 CAPNTWQLASGT--GCDPCNCNAAHSFG--PSCNEFTGQCQCMPGFGGRTCSECQELFWG 1123
C P W L+ GC C+C+ + G C TGQC C P G+ C+ C++ F+G
Sbjct: 758 CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFG 817
Query: 1124 DPDVE---CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 1169
+ CR+C CD G C+ TG C C +GP C + R +
Sbjct: 818 LDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Score = 234 bits (596), Expect = 7e-61
Identities = 214/827 (25%), Positives = 306/827 (37%), Gaps = 188/827 (22%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C + G +C C Y P C+ C+C
Sbjct: 1455 GQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGAR--------------- 1489
Query: 356 NVSGGVCDD------CQHNTMGRNCEQCKPFYYQ-HPERDIRDPNFCERCTCDPAGSQNE 408
+CD+ C T+ +C C+P + HP CE C C G Q
Sbjct: 1490 -----LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVG------CEECNCSGPGIQE- 1537
Query: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPG 468
TD + +GQC+C+ NV G CD C GF+ C+ C C+ GT PG
Sbjct: 1538 -----LTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPG 1587
Query: 469 GNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQ 528
CD TG CYCK V G CDQC + L D P C CF
Sbjct: 1588 --VCDPLTGQCYCKENVQGPKCDQCSLGTFSL----DAANPKGC-------TRCFCFGAT 1634
Query: 529 CSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIV--ERQYIQDRIPSWTGA 586
CR RQ G+ + D + E PG ++ + +++ + +P
Sbjct: 1635 ERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQ---PGTEMLRADLRHVPEAVPEAFPE 1691
Query: 587 GFVRVPEGAYLEFFIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNT 646
+ + P +YL + + ++ Y++ E Q D + +P SR
Sbjct: 1692 LYWQAPP-SYLGDRVSSYGGTLRYEL--HSETQRGDVF------------VPMESRPDVV 1736
Query: 647 IPDDDNQVVSLSPGSRYVVLPRPVCFEKGT--------------NYTVRLELPQYTSS-- 690
+ + + L P P P +G N R EL +S
Sbjct: 1737 LQGNQMSITFLEPA-----YPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLE 1791
Query: 691 DSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTP 750
+ + ++ I S V + + + + +G G + ++ + C + R
Sbjct: 1792 QLQIRALFSQISSAVFL---RRVALEVASPAGQGALASNV----ELCLCPASYRG----- 1839
Query: 751 MTDVCRN----IIFSISALLHQTGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNR 805
D C+ + L + C+C S C P G C C+ N G C R
Sbjct: 1840 --DSCQECAPGFYRDVKGLFLGRCVPCQCHGH---SDRCLPGSGVCVDCQHNTEGAHCER 1894
Query: 806 CAPGTFGF--GPSG-CKPCECHLQGSVNAFCNPVT-----GQCHCFQGVYARQCDRCLPG 857
C G PS C C C L N F QC C G C+RC PG
Sbjct: 1895 CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPG 1954
Query: 858 HWGFP-----SCQPCQCNGHAD------DCDPVTGECLNCQDYTMGHNCERCLAGYYGDP 906
+G P SCQPC C+G+ D DCDP+TG C C +T G CE C G+YG+
Sbjct: 1955 FFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNA 2014
Query: 907 II-GSGDHCRPCPCPD---GPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGY 962
++ G+ C PC P SG C+C G G RCD C G+
Sbjct: 2015 LLPGNCTRCDCTPCGTEACDPHSGH----------------CLCKAGVTGRRCDRCQEGH 2058
Query: 963 FGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQ 1022
FG + G C+PC C + C ++G+C C T G C+ C GY+G +
Sbjct: 2059 FG--FDGCGGCRPCACG---PAAEGSECHPQSGQC-HCRPGTMGPQCRECAPGYWG-LPE 2111
Query: 1023 QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Q CR+C C +CD TG+C C P + G+ CD C+
Sbjct: 2112 QGCRRCQC------------PGGRCDPHTGRCNCPPGLSGERCDTCS 2146
Score = 215 bits (547), Expect = 4e-55
Identities = 141/410 (34%), Positives = 175/410 (42%), Gaps = 81/410 (19%)
Query: 821 CECHLQGSVNAF-----CNPVTGQCHCFQGVYARQCDRCLPGHWGFP----------SCQ 865
C CH G +A +P QC C CDRC PG P CQ
Sbjct: 300 CVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
Query: 866 PCQCNGHADDC--DPVT----------------GECLNCQDYTMGHNCERCLAGYYGDP- 906
C C GHA DC DP G C++CQ +T G NCERCL G+Y P
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
Query: 907 -IIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGN 965
+ S CR C C F +D L C C P + G RCD CA G+ G
Sbjct: 418 HPLDSPHVCRRCNCES------DFTDGTCED---LTGRCYCRPNFSGERCDVCAEGFTGF 468
Query: 966 PS-------------EVGGSCQPCQCHNNIDTTDPEAC--DKETGRCLKCLYHTEGEHCQ 1010
PS +V + Q C + T AC D GRCL C + +G HC+
Sbjct: 469 PSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCE 527
Query: 1011 FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAP 1070
C G+YG C+ C C+ G +D +CD TGQC C G CDRCAP
Sbjct: 528 LCAPGFYGPG----CQPCQCSSPGV-------ADDRCDPDTGQCRCRVGFEGATCDRCAP 576
Query: 1071 NTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECR 1130
+ C C C+ A + C+E G+C C P F G C C+ + G P+ C+
Sbjct: 577 GYFHFPL---CQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYHGFPN--CQ 630
Query: 1131 ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 1180
AC CDPRG C + G C C G G C +C+ G+ G FP C PCH
Sbjct: 631 ACTCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHG-FPSCVPCH 678
Score = 174 bits (442), Expect = 5e-43
Identities = 128/382 (33%), Positives = 166/382 (43%), Gaps = 60/382 (15%)
Query: 778 QGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTF----GFGPSGCKPCECHLQGSVNAFC 833
QG+L+S N C C + G +C CAPG + G C PC+CH + C
Sbjct: 1821 QGALAS----NVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCH---GHSDRC 1873
Query: 834 NPVTGQC-HCFQGVYARQCDRCLPGHWGF---PS--CQPCQC------NGHADDCDPVTG 881
P +G C C C+RC G PS C C C N A+ C G
Sbjct: 1874 LPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGG 1933
Query: 882 --ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVT 939
+CL C+ G +CERC G++G+P++ G C+PC C D F+ C DP+T
Sbjct: 1934 RTQCL-CKPGYAGASCERCAPGFFGNPLV-LGSSCQPCDCSGNGDPNLLFS-DC--DPLT 1988
Query: 940 LQLAC-VCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCL 998
AC C G RC+ CA G++GN + + G+C C C EACD +G CL
Sbjct: 1989 --GACRGCLRHTTGPRCEICAPGFYGN-ALLPGNCTRCDC----TPCGTEACDPHSGHCL 2041
Query: 999 KCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLP 1058
C G C C+ G++G CR C C G E GS+C +GQC C P
Sbjct: 2042 -CKAGVTGRRCDRCQEGHFGFDGCGGCRPCAC---GPAAE---GSECH--PQSGQCHCRP 2092
Query: 1059 NVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118
+G C CAP W L GC C C G C+ TG+C C PG G C C
Sbjct: 2093 GTMGPQCRECAPGYWGLPE-QGCRRCQCP-----GGRCDPHTGRCNCPPGLSGERCDTCS 2146
Query: 1119 ELFW----GDP---DVECRACD 1133
+ G P + C CD
Sbjct: 2147 QQHQVPVPGGPVGHSIHCEVCD 2168
Score = 160 bits (405), Expect = 1e-38
Identities = 98/303 (32%), Positives = 129/303 (42%), Gaps = 44/303 (14%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLP----------------------WRPAEGRNSNACK 333
G C+C+ G +C+ C YH P R G AC+
Sbjct: 603 GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
Query: 334 KCNCNEHS----ISCHFDMAVYL-ATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
+C+ H + CH L A + G C C+ G C+ C P Y P
Sbjct: 663 ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCS-CRPRVTGLRCDTCVPGAYNFP--- 718
Query: 389 IRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLS 448
+CE +C PAG + D + C C+ +VEG CD CK GF+ LS
Sbjct: 719 -----YCEAGSCHPAGL-------APVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLS 766
Query: 449 SEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN-DLDGC 507
+P GC C+C+ GT+ G C TG C+CK V GQ C C +GL D GC
Sbjct: 767 PSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 826
Query: 508 RPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPG 567
R C CD+GGAL SC +G C CRP+ G C+E +Y L H E EEA G
Sbjct: 827 RSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEG 886
Query: 568 VSI 570
++
Sbjct: 887 HAV 889
Score = 148 bits (374), Expect = 4e-35
Identities = 94/281 (33%), Positives = 124/281 (44%), Gaps = 40/281 (14%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSN 330
C C+GH+ C P G + C+HNT+G +CE C + P S
Sbjct: 1864 CQCHGHSDRCLPGSGVCVD----------CQHNTEGAHCERCQAGFVSSRDDP-----SA 1908
Query: 331 ACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIR 390
C C C S +F L G C C+ G +CE+C P ++ +P +
Sbjct: 1909 PCVSCPCPLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFFGNP---LV 1961
Query: 391 DPNFCERCTCDPAGSQNE--GICDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGFYDL 447
+ C+ C C G N CD T G CR C + G C++C GFY
Sbjct: 1962 LGSSCQPCDCSGNGDPNLLFSDCDPLT--------GACRGCLRHTTGPRCEICAPGFYG- 2012
Query: 448 SSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC 507
++ P C C C P GT CD +GHC CK VTG+ CD+C H+G GC
Sbjct: 2013 NALLPGNCTRCDCTPCGT----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDG-CGGC 2067
Query: 508 RPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
RPC C A + C +SGQC CRP +G QC E PGY+
Sbjct: 2068 RPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW 2107
Score = 147 bits (372), Expect = 7e-35
Identities = 103/347 (29%), Positives = 144/347 (41%), Gaps = 103/347 (29%)
Query: 270 NCFCYGHASEC---APVDG--FNEEVEGMVHGH--CM-CRHNTKGLNCELCMDFYHDLPW 321
+C CYGHA++C VD ++ ++G G C+ C+H+T G+NCE C+ ++ P
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
Query: 322 RPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD------CQHNTMGRNCE 375
P + + + C++CNC + + G C+D C+ N G C+
Sbjct: 418 HPLD--SPHVCRRCNCES----------------DFTDGTCEDLTGRCYCRPNFSGERCD 459
Query: 376 QCK------PFYYQHPE--RDIRD-----------------------------------P 392
C P Y P D R+ P
Sbjct: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
Query: 393 NF----CERCT-------CDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCK 441
NF CE C C P + G+ D D TG QCRC++ EG CD C
Sbjct: 520 NFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTG----QCRCRVGFEGATCDRCA 575
Query: 442 EGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLS 501
G++ C+ C C+P GT+P G CD E G C C+ G HCD+C P + G
Sbjct: 576 PGYFHFPL-----CQLCGCSPAGTLPEG--CD-EAGRCLCQPEFAGPHCDRCRPGYHGFP 627
Query: 502 NDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
N C+ C CD GAL+ C A G C CRP G C E PG++
Sbjct: 628 N----CQACTCDPRGALDQLCGA-GGLCRCRPGYTGTACQECSPGFH 669
Score = 145 bits (366), Expect = 3e-34
Identities = 80/231 (34%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP 862
C A F +G +PC CH G+ C P GQC C V R C RC G+WGFP
Sbjct: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP 1479
Query: 863 SCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYG-DPIIGSGDHCRPCPCPD 921
+C+PC C CD +TG+C+ C T+ +C C +G P++G C C C
Sbjct: 1480 NCRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNC-S 1531
Query: 922 GPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNN 981
GP +C D C C P G RCD C+ G+ G P C+PC CH
Sbjct: 1532 GPGIQELTDPTCDTD----SGQCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHE- 1581
Query: 982 IDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYG--DALQQDCRKCVC 1030
T P CD TG+C C + +G C C G + A + C +C C
Sbjct: 1582 -AGTAPGVCDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 141 bits (356), Expect = 5e-33
Identities = 78/214 (36%), Positives = 101/214 (47%), Gaps = 24/214 (11%)
Query: 974 QPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYL 1033
+PC CH + T P C+ G+C C H G C C GY+G +CR C C
Sbjct: 1436 RPCGCHE-VGATGP-TCEPFGGQC-PCHAHVIGRDCSRCATGYWGFP---NCRPCDCGAR 1489
Query: 1034 GTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAA---H 1090
CD+ TGQC+C P I +C C P T+ GC+ CNC+
Sbjct: 1490 ------------LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQE 1537
Query: 1091 SFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQ 1150
P+C+ +GQC+C P GR C C F G P CR CDC G CD TGQ
Sbjct: 1538 LTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPGVCDPLTGQ 1595
Query: 1151 CVCVEGVEGPRCDKCTRG-YSGVFPDCTPCHQCF 1183
C C E V+GP+CD+C+ G +S + C +CF
Sbjct: 1596 CYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCF 1629
Score = 132 bits (333), Expect = 2e-30
Identities = 84/242 (34%), Positives = 113/242 (46%), Gaps = 24/242 (9%)
Query: 685 PQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWE--TFQRYRCLEN 742
P Y + + +P + LVL C+ D G+GD + S + T CL +
Sbjct: 1941 PGYAGASCERCAPGFFGNPLVLGSSCQPCDC---SGNGDPNLLFSDCDPLTGACRGCLRH 1997
Query: 743 SRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRT 802
+ P ++C + +ALL C+C P G+ CDP+ G C C+ V GR
Sbjct: 1998 TTG----PRCEICAPGFYG-NALLPGNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRR 2050
Query: 803 CNRCAPGTFGF-GPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF 861
C+RC G FGF G GC+PC C + + C+P +GQCHC G QC C PG+WG
Sbjct: 2051 CDRCQEGHFGFDGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 2109
Query: 862 P--SCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYY----GDPIIGSGDHCR 915
P C+ CQC G CDP TG C NC G C+ C + G P +G HC
Sbjct: 2110 PEQGCRRCQCPG--GRCDPHTGRC-NCPPGLSGERCDTCSQQHQVPVPGGP-VGHSIHCE 2165
Query: 916 PC 917
C
Sbjct: 2166 VC 2167
Score = 131 bits (330), Expect = 5e-30
Identities = 76/234 (32%), Positives = 103/234 (44%), Gaps = 33/234 (14%)
Query: 755 CRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFG 814
CRN S+S + C C G+ C+P GGQC C +V+GR C+RCA G +GF
Sbjct: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF- 1478
Query: 815 PSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWG---FPSCQPCQCNG 871
C+PC+C + C+ +TGQC C C C P +G C+ C C+G
Sbjct: 1479 -PNCRPCDCGAR-----LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSG 1532
Query: 872 HA------DDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPD-GPD 924
CD +G+C C+ G C+ C G++G P CRPC C + G
Sbjct: 1533 PGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHGYP------RCRPCDCHEAGTA 1585
Query: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
G DP+T Q C C G +CD C+ G F + C C C
Sbjct: 1586 PG-------VCDPLTGQ--CYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 94.4 bits (233), Expect = 9e-19
Identities = 63/224 (28%), Positives = 91/224 (40%), Gaps = 44/224 (19%)
Query: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVS---GGVCDDCQHNTMGRNCEQCKPFYYQHP 385
+N + C C+E ATG GG C C + +GR+C +C Y+ P
Sbjct: 1432 NNGARPCGCHEVG-----------ATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWGFP 1479
Query: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
C C C +CD T GQC C C +C+ +
Sbjct: 1480 N--------CRPCDCGAR------LCDELT--------GQCICPPRTIPPDCLLCQPQTF 1517
Query: 446 DLSSEDPFGCKSCACNPLGTIPGGNP-CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
GC+ C C+ G +P CD+++G C C+ VTG+ CD C P G
Sbjct: 1518 --GCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-- 1573
Query: 505 DGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
CRPCDC G C +GQC C+ ++ G +C++ G +
Sbjct: 1574 --CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1615
Score = 85.1 bits (209), Expect = 6e-16
Identities = 60/207 (28%), Positives = 80/207 (38%), Gaps = 46/207 (22%)
Query: 269 GNCFCYGHA---------------SECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCM 313
G C C+ H C P D + + G C+C T +C LC
Sbjct: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELT-GQCICPPRTIPPDCLLCQ 1513
Query: 314 DFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRN 373
P G C++CNC+ I D T + G C C+ N GR
Sbjct: 1514 P--QTFGCHPLVG-----CEECNCSGPGIQELTD-----PTCDTDSGQCK-CRPNVTGRR 1560
Query: 374 CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVE 433
C+ C P ++ +P C C C AG+ G+CD T GQC CK NV+
Sbjct: 1561 CDTCSPGFHGYPR--------CRPCDCHEAGTA-PGVCDPLT--------GQCYCKENVQ 1603
Query: 434 GEHCDVCKEGFYDLSSEDPFGCKSCAC 460
G CD C G + L + +P GC C C
Sbjct: 1604 GPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 83.2 bits (204), Expect = 2e-15
Identities = 48/158 (30%), Positives = 60/158 (37%), Gaps = 46/158 (29%)
Query: 1067 RCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPD 1126
R A + L G PC C+ + GP+C F GQC C GR CS C +WG P+
Sbjct: 1421 RNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN 1480
Query: 1127 ------------------------------------------VECRACDCDPRGIE---T 1141
V C C+C GI+
Sbjct: 1481 CRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTD 1540
Query: 1142 PQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPC 1179
P CD +GQC C V G RCD C+ G+ G +P C PC
Sbjct: 1541 PTCDTDSGQCKCRPNVTGRRCDTCSPGFHG-YPRCRPC 1577
Score = 79.0 bits (193), Expect = 4e-14
Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 5/121 (4%)
Query: 744 RSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSV--CDPNGGQCQCRPNVVGR 801
R+ V+ P D C+ + +S + C CD +G+L V C P GQC C+P+V G+
Sbjct: 747 RAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQ 806
Query: 802 TCNRCAPGTFGFGPS---GCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
C C G FG + GC+ C C + G++ C P TG C C C H
Sbjct: 807 ACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Query: 859 W 859
+
Sbjct: 867 Y 867
Score = 32.3 bits (72), Expect = 4.2
Identities = 22/65 (33%), Positives = 24/65 (36%), Gaps = 14/65 (21%)
Query: 1375 ARLLDELAG------KLQSLDLSAAAEMTCGTPPGASCSETECGGPN--------CRTDE 1420
ARL DEL G + D T G P C E C GP C TD
Sbjct: 1488 ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDS 1547
Query: 1421 GERKC 1425
G+ KC
Sbjct: 1548 GQCKC 1552
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 277 bits (708), Expect = 8e-74
Identities = 162/482 (33%), Positives = 240/482 (49%), Gaps = 53/482 (10%)
Query: 89 LNPDSHLIE-----NVVTTFAPNRLKIWWQSENGVENVTIQLDLE-AEFHFTHLIMTFKT 142
LNP++H + +V T++ N Q GV TI +DLE ++ ++I+ F +
Sbjct: 335 LNPEAHPLSFVNDNDVGTSWVSNVFTNITQLNQGV---TISVDLENGQYQVFYIIIQFFS 391
Query: 143 FRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE 202
+P + I+R + W ++YFA +C A F + G ++K D + C + S+ P +
Sbjct: 392 PQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSR 449
Query: 203 GEVIFRALDPAFKIEDPYS-----PRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREK 257
G V F L P Y+ P +Q +K T +R F + + ++ R
Sbjct: 450 GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR---- 505
Query: 258 YYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHN--TKGLNCELCMDF 315
YYAV ++ + G C C+GHA C D ++ C+C T+GL+C+ C+
Sbjct: 506 -YYAVDEITISGRCQCHGHADNC---DTTSQPYR------CLCSQESFTEGLHCDRCLPL 555
Query: 316 YHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY---LATGNVSGGVCDDCQHNTMGR 372
Y+D P+R + + CK C CN HS SCH++++V GGVCDDC+HNT GR
Sbjct: 556 YNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGR 615
Query: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGI-CDSYTDFSTGLIAGQCRCKLN 431
NCE CK ++++ D + C+ C CD G++N I CD I GQC CK +
Sbjct: 616 NCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ--------IGGQCNCKRH 667
Query: 432 VEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD 491
V G C+ C+ GFY+L DP GC C CN GT+ G C +G C CK V G CD
Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 492 QCLPEHWGLS-----NDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPG 546
C ++G ND+ GC PC C+L G++N C SGQC C+ G QC+
Sbjct: 728 HC---NFGFKFLRSFNDV-GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCREN 783
Query: 547 YY 548
+Y
Sbjct: 784 FY 785
Score = 240 bits (613), Expect = 8e-63
Identities = 138/417 (33%), Positives = 194/417 (46%), Gaps = 46/417 (11%)
Query: 773 CECDPQGSL--SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCKPCECHLQG 827
C+CD G+ S +CD GGQC C+ +V GR CN+C G + P GC PC C+ G
Sbjct: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSG 700
Query: 828 SVNA--FCNPVTGQCHCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNGHADD-- 875
+V+ C+ +GQC C V +CD C ++GF C+PCQCN H
Sbjct: 701 TVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVNK 757
Query: 876 -CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCY 934
C+P +G+C C+ G C+ C +YG + +C+ C C +G C
Sbjct: 758 FCNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT----NCKACDCDT---AGSLPGTVC- 808
Query: 935 QDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKET 994
+ T Q C+C P G +C+ C G F C PC C C+K T
Sbjct: 809 -NAKTGQ--CICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKST 865
Query: 995 GRCLKCLYHTEGEHCQFCRFGYYGDALQ--QDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
G+C C G C C Y + Q C+ C C+ LGT+ CD +G
Sbjct: 866 GQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI------CDPISG 918
Query: 1053 QCLCLPNVIGQNCDRCAPNTW-QLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPG-FG 1110
QCLC+PN G+ C++C P + + TGC PC+C+ + CN TGQC C
Sbjct: 919 QCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA 978
Query: 1111 GRTCSECQELFWG-DPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC 1165
G+ C +C++ ++G DP C+ C+C G C TGQC C + V G +CD C
Sbjct: 979 GQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 204 bits (520), Expect = 5e-52
Identities = 131/425 (30%), Positives = 192/425 (45%), Gaps = 44/425 (10%)
Query: 710 CKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQT 769
CK D TVG ++ + +C N + V + C+N +++ L
Sbjct: 638 CKPCDCDTVGTRNGSILCDQIGG-----QC--NCKRHVSGRQCNQCQNGFYNLQELDPDG 690
Query: 770 GLACECDPQGSLSS--VCDPNGGQCQCRPNVVGRTCNRCAPG---TFGFGPSGCKPCECH 824
C C+ G++ C N GQC+C+ NV+G C+ C G F GC+PC+C+
Sbjct: 691 CSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750
Query: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF--PSCQPCQCNGHAD----DCDP 878
L GSVN FCNP +GQC C + QCD C +G +C+ C C+ C+
Sbjct: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 879 VTGECLNCQDYTMGHNCERCLAG-YYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDP 937
TG+C+ C+ G C +CL G +Y + C PC C D S +
Sbjct: 811 KTGQCI-CKPNVEGRQCNKCLEGNFYLRQ--NNSFLCLPCNC----DKTGTINGSLLCNK 863
Query: 938 VTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRC 997
T Q C C G G RC+ C + + CQ C+C +++ T CD +G+C
Sbjct: 864 STGQ--CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC-DSLGTLPGTICDPISGQC 920
Query: 998 LKCLYHTEGEHCQFCRFGYY---GDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQC 1054
L C+ + +G C C+ G+Y G+A C C C+ G V CN TGQC
Sbjct: 921 L-CVPNRQGRRCNQCQPGFYISPGNA--TGCLPCSCHTTGAVNHICN-------SLTGQC 970
Query: 1055 LCL-PNVIGQNCDRCAPNTWQLASGTG-CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
+C ++ GQ CD+C + + TG C PCNC+ + + +C+ TGQC C G
Sbjct: 971 VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS 1030
Query: 1113 TCSEC 1117
C C
Sbjct: 1031 KCDAC 1035
Score = 202 bits (514), Expect = 2e-51
Identities = 162/562 (28%), Positives = 231/562 (41%), Gaps = 89/562 (15%)
Query: 672 FEKGTNYTVRLELPQYTSSDS-DVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSA 730
F K T YT+ + ++ Y +D + + C+ G D T S
Sbjct: 479 FVKATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQC------HGHADNCDTTS- 531
Query: 731 WETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQ--GSLSSVCDPN 788
Q YRCL + S + D C + A C P S S C N
Sbjct: 532 ----QPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYN 587
Query: 789 --------------GGQCQ-CRPNVVGRTCNRCAPGTF---GFGPSG---CKPCECHLQG 827
GG C C N GR C C F G PS CKPC+C G
Sbjct: 588 ISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVG 647
Query: 828 SVNA--FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCN--GHADD--- 875
+ N C+ + GQC+C + V RQC++C G + C PC CN G D
Sbjct: 648 TRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDIT 707
Query: 876 CDPVTGECLNCQDYTMGHNCERCLAGY-----YGDPIIGSGDHCRPCPCPDGPDSGRQFA 930
C +G+C C+ +G C+ C G+ + D +G C PC C +
Sbjct: 708 CHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND--VG----CEPCQC------NLHGS 754
Query: 931 RSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEAC 990
+ + +P + Q C C G +CD C ++G +C+ C C + + C
Sbjct: 755 VNKFCNPHSGQ--CECKKEAKGLQCDTCRENFYGLDVT---NCKACDC-DTAGSLPGTVC 808
Query: 991 DKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQ 1046
+ +TG+C+ C + EG C C G + L+Q+ C C C+ GT+ NGS
Sbjct: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTI----NGS-LL 860
Query: 1047 CDKATGQCLCLPNVIGQNCDRCAPNTWQLASGT--GCDPCNCNAAHSF-GPSCNEFTGQC 1103
C+K+TGQC C V G C++C P+ + L C C C++ + G C+ +GQC
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQC 920
Query: 1104 QCMPGFGGRTCSECQELFWGDPD--VECRACDCDPRGIETPQCDQSTGQCVCVEG-VEGP 1160
C+P GR C++CQ F+ P C C C G C+ TGQCVC + + G
Sbjct: 921 LCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980
Query: 1161 RCDKCTRGYSGVFPDCTPCHQC 1182
RCD+C Y G P C C
Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPC 1002
Score = 172 bits (437), Expect = 2e-42
Identities = 100/315 (31%), Positives = 143/315 (45%), Gaps = 31/315 (9%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSV-NA 831
C+C+ GS++ C+P+ GQC+C+ G C+ C +G + CK C+C GS+
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806
Query: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCNGHADD-----CDPVTG 881
CN TGQC C V RQC++CL G++ C PC C+ C+ TG
Sbjct: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866
Query: 882 ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ 941
+C C+ G C +C Y + I + HC+ C C G C DP++ Q
Sbjct: 867 QC-PCKLGVTGLRCNQCEPHRY-NLTIDNFQHCQMCECDS---LGTLPGTIC--DPISGQ 919
Query: 942 LACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001
C+C P G RC+ C G++ +P G C PC CH C+ TG+C+
Sbjct: 920 --CLCVPNRQGRRCNQCQPGFYISPGNATG-CLPCSCHTTGAVN--HICNSLTGQCVCQD 974
Query: 1002 YHTEGEHCQFCRFGYYG-DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNV 1060
G+ C C+ Y+G D C+ C C+ G + E C+ TGQC C V
Sbjct: 975 ASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCH-------LVTGQCFCKQFV 1027
Query: 1061 IGQNCDRCAPNTWQL 1075
G CD C P+ L
Sbjct: 1028 TGSKCDACVPSASHL 1042
Score = 160 bits (404), Expect = 1e-38
Identities = 90/257 (35%), Positives = 122/257 (47%), Gaps = 30/257 (11%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C+ N GL C+ C + ++ N C+ C CN H F
Sbjct: 713 GQCKCKANVIGLRCDHC-----NFGFKFLRSFNDVGCEPCQCNLHGSVNKFC-------- 759
Query: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
N G C+ C+ G C+ C+ +Y D C+ C CD AGS +C++ T
Sbjct: 760 NPHSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAKT 812
Query: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
GQC CK NVEG C+ C EG + L + F C C C+ GTI G C+
Sbjct: 813 --------GQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864
Query: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDCDLGGALNNS-CFAESGQCSCRP 533
TG C CK VTG C+QC P + L+ D C+ C+CD G L + C SGQC C P
Sbjct: 865 TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924
Query: 534 HMIGRQCNEVEPGYYFA 550
+ GR+CN+ +PG+Y +
Sbjct: 925 NRQGRRCNQCQPGFYIS 941
Score = 148 bits (374), Expect = 4e-35
Identities = 85/258 (32%), Positives = 121/258 (46%), Gaps = 41/258 (15%)
Query: 296 GHCMCRHNTKGLNCELCMD--FYHDLPWRPAEGRNSNACKKCNCNEH-----SISCHFDM 348
G C+C+ N +G C C++ FY NS C CNC++ S+ C
Sbjct: 813 GQCICKPNVEGRQCNKCLEGNFY-------LRQNNSFLCLPCNCDKTGTINGSLLC---- 861
Query: 349 AVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE 408
N S G C C+ G C QC+P Y I + C+ C CD G+
Sbjct: 862 -------NKSTGQCP-CKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPG 910
Query: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPG 468
ICD I+GQC C N +G C+ C+ GFY +S + GC C+C+ G +
Sbjct: 911 TICDP--------ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAV-- 959
Query: 469 GNPCDSETGHCYCKRL-VTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESG 527
+ C+S TG C C+ + GQ CDQC ++G C+PC+C L GALN +C +G
Sbjct: 960 NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG 1019
Query: 528 QCSCRPHMIGRQCNEVEP 545
QC C+ + G +C+ P
Sbjct: 1020 QCFCKQFVTGSKCDACVP 1037
Score = 137 bits (344), Expect = 1e-31
Identities = 80/263 (30%), Positives = 123/263 (46%), Gaps = 46/263 (17%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C+ KGL C+ C + ++ G + CK C+C+ G
Sbjct: 764 GQCECKKEAKGLQCDTCRENFY--------GLDVTNCKACDCD--------------TAG 801
Query: 356 NVSGGVCDD------CQHNTMGRNCEQCKP--FYYQHPERDIRDPNFCERCTCDPAGSQN 407
++ G VC+ C+ N GR C +C FY + + C C CD G+ N
Sbjct: 802 SLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ-----NNSFLCLPCNCDKTGTIN 856
Query: 408 EGI-CDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTI 466
+ C+ T GQC CKL V G C+ C+ Y+L+ ++ C+ C C+ LGT+
Sbjct: 857 GSLLCNKST--------GQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908
Query: 467 PGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAES 526
PG CD +G C C G+ C+QC P + + GC PC C GA+N+ C + +
Sbjct: 909 PG-TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLT 967
Query: 527 GQCSCRPHMI-GRQCNEVEPGYY 548
GQC C+ I G++C++ + Y+
Sbjct: 968 GQCVCQDASIAGQRCDQCKDHYF 990
Score = 87.4 bits (215), Expect = 1e-16
Identities = 37/89 (41%), Positives = 54/89 (60%), Gaps = 3/89 (3%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRP-NVVGRTCNRCAPGTFGFGPSG--CKPCECHLQG 827
L C C G+++ +C+ GQC C+ ++ G+ C++C FGF P C+PC CHL G
Sbjct: 949 LPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSG 1008
Query: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLP 856
++N C+ VTGQC C Q V +CD C+P
Sbjct: 1009 ALNETCHLVTGQCFCKQFVTGSKCDACVP 1037
Score = 69.7 bits (169), Expect = 2e-11
Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 29/163 (17%)
Query: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
+ G C+C N +G C C ++ P N+ C C SCH AV
Sbjct: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC-------SCHTTGAVNHI 962
Query: 354 TGNVSGG-VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICD 412
+++G VC D + G+ C+QCK Y+ + R C+ C C +G+ NE
Sbjct: 963 CNSLTGQCVCQDA--SIAGQRCDQCKDHYFGFDPQTGR----CQPCNCHLSGALNE---- 1012
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGC 455
+ L+ GQC CK V G CD C L + GC
Sbjct: 1013 -----TCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 277 bits (708), Expect = 8e-74
Identities = 162/482 (33%), Positives = 240/482 (49%), Gaps = 53/482 (10%)
Query: 89 LNPDSHLIE-----NVVTTFAPNRLKIWWQSENGVENVTIQLDLE-AEFHFTHLIMTFKT 142
LNP++H + +V T++ N Q GV TI +DLE ++ ++I+ F +
Sbjct: 335 LNPEAHPLSFVNDNDVGTSWVSNVFTNITQLNQGV---TISVDLENGQYQVFYIIIQFFS 391
Query: 143 FRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE 202
+P + I+R + W ++YFA +C A F + G ++K D + C + S+ P +
Sbjct: 392 PQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSR 449
Query: 203 GEVIFRALDPAFKIEDPYS-----PRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREK 257
G V F L P Y+ P +Q +K T +R F + + ++ R
Sbjct: 450 GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR---- 505
Query: 258 YYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHN--TKGLNCELCMDF 315
YYAV ++ + G C C+GHA C D ++ C+C T+GL+C+ C+
Sbjct: 506 -YYAVDEITISGRCQCHGHADNC---DTTSQPYR------CLCSQESFTEGLHCDRCLPL 555
Query: 316 YHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY---LATGNVSGGVCDDCQHNTMGR 372
Y+D P+R + + CK C CN HS SCH++++V GGVCDDC+HNT GR
Sbjct: 556 YNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGR 615
Query: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGI-CDSYTDFSTGLIAGQCRCKLN 431
NCE CK ++++ D + C+ C CD G++N I CD I GQC CK +
Sbjct: 616 NCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ--------IGGQCNCKRH 667
Query: 432 VEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD 491
V G C+ C+ GFY+L DP GC C CN GT+ G C +G C CK V G CD
Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 492 QCLPEHWGLS-----NDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPG 546
C ++G ND+ GC PC C+L G++N C SGQC C+ G QC+
Sbjct: 728 HC---NFGFKFLRSFNDV-GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCREN 783
Query: 547 YY 548
+Y
Sbjct: 784 FY 785
Score = 240 bits (613), Expect = 8e-63
Identities = 138/417 (33%), Positives = 194/417 (46%), Gaps = 46/417 (11%)
Query: 773 CECDPQGSL--SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCKPCECHLQG 827
C+CD G+ S +CD GGQC C+ +V GR CN+C G + P GC PC C+ G
Sbjct: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSG 700
Query: 828 SVNA--FCNPVTGQCHCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNGHADD-- 875
+V+ C+ +GQC C V +CD C ++GF C+PCQCN H
Sbjct: 701 TVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVNK 757
Query: 876 -CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCY 934
C+P +G+C C+ G C+ C +YG + +C+ C C +G C
Sbjct: 758 FCNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT----NCKACDCDT---AGSLPGTVC- 808
Query: 935 QDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKET 994
+ T Q C+C P G +C+ C G F C PC C C+K T
Sbjct: 809 -NAKTGQ--CICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKST 865
Query: 995 GRCLKCLYHTEGEHCQFCRFGYYGDALQ--QDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
G+C C G C C Y + Q C+ C C+ LGT+ CD +G
Sbjct: 866 GQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI------CDPISG 918
Query: 1053 QCLCLPNVIGQNCDRCAPNTW-QLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPG-FG 1110
QCLC+PN G+ C++C P + + TGC PC+C+ + CN TGQC C
Sbjct: 919 QCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA 978
Query: 1111 GRTCSECQELFWG-DPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC 1165
G+ C +C++ ++G DP C+ C+C G C TGQC C + V G +CD C
Sbjct: 979 GQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 204 bits (520), Expect = 5e-52
Identities = 131/425 (30%), Positives = 192/425 (45%), Gaps = 44/425 (10%)
Query: 710 CKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQT 769
CK D TVG ++ + +C N + V + C+N +++ L
Sbjct: 638 CKPCDCDTVGTRNGSILCDQIGG-----QC--NCKRHVSGRQCNQCQNGFYNLQELDPDG 690
Query: 770 GLACECDPQGSLSS--VCDPNGGQCQCRPNVVGRTCNRCAPG---TFGFGPSGCKPCECH 824
C C+ G++ C N GQC+C+ NV+G C+ C G F GC+PC+C+
Sbjct: 691 CSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750
Query: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF--PSCQPCQCNGHAD----DCDP 878
L GSVN FCNP +GQC C + QCD C +G +C+ C C+ C+
Sbjct: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 879 VTGECLNCQDYTMGHNCERCLAG-YYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDP 937
TG+C+ C+ G C +CL G +Y + C PC C D S +
Sbjct: 811 KTGQCI-CKPNVEGRQCNKCLEGNFYLRQ--NNSFLCLPCNC----DKTGTINGSLLCNK 863
Query: 938 VTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRC 997
T Q C C G G RC+ C + + CQ C+C +++ T CD +G+C
Sbjct: 864 STGQ--CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC-DSLGTLPGTICDPISGQC 920
Query: 998 LKCLYHTEGEHCQFCRFGYY---GDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQC 1054
L C+ + +G C C+ G+Y G+A C C C+ G V CN TGQC
Sbjct: 921 L-CVPNRQGRRCNQCQPGFYISPGNA--TGCLPCSCHTTGAVNHICN-------SLTGQC 970
Query: 1055 LCL-PNVIGQNCDRCAPNTWQLASGTG-CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
+C ++ GQ CD+C + + TG C PCNC+ + + +C+ TGQC C G
Sbjct: 971 VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS 1030
Query: 1113 TCSEC 1117
C C
Sbjct: 1031 KCDAC 1035
Score = 202 bits (514), Expect = 2e-51
Identities = 162/562 (28%), Positives = 231/562 (41%), Gaps = 89/562 (15%)
Query: 672 FEKGTNYTVRLELPQYTSSDS-DVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSA 730
F K T YT+ + ++ Y +D + + C+ G D T S
Sbjct: 479 FVKATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQC------HGHADNCDTTS- 531
Query: 731 WETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQ--GSLSSVCDPN 788
Q YRCL + S + D C + A C P S S C N
Sbjct: 532 ----QPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYN 587
Query: 789 --------------GGQCQ-CRPNVVGRTCNRCAPGTF---GFGPSG---CKPCECHLQG 827
GG C C N GR C C F G PS CKPC+C G
Sbjct: 588 ISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVG 647
Query: 828 SVNA--FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCN--GHADD--- 875
+ N C+ + GQC+C + V RQC++C G + C PC CN G D
Sbjct: 648 TRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDIT 707
Query: 876 CDPVTGECLNCQDYTMGHNCERCLAGY-----YGDPIIGSGDHCRPCPCPDGPDSGRQFA 930
C +G+C C+ +G C+ C G+ + D +G C PC C +
Sbjct: 708 CHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND--VG----CEPCQC------NLHGS 754
Query: 931 RSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEAC 990
+ + +P + Q C C G +CD C ++G +C+ C C + + C
Sbjct: 755 VNKFCNPHSGQ--CECKKEAKGLQCDTCRENFYGLDVT---NCKACDC-DTAGSLPGTVC 808
Query: 991 DKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQ 1046
+ +TG+C+ C + EG C C G + L+Q+ C C C+ GT+ NGS
Sbjct: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTI----NGS-LL 860
Query: 1047 CDKATGQCLCLPNVIGQNCDRCAPNTWQLASGT--GCDPCNCNAAHSF-GPSCNEFTGQC 1103
C+K+TGQC C V G C++C P+ + L C C C++ + G C+ +GQC
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQC 920
Query: 1104 QCMPGFGGRTCSECQELFWGDPD--VECRACDCDPRGIETPQCDQSTGQCVCVEG-VEGP 1160
C+P GR C++CQ F+ P C C C G C+ TGQCVC + + G
Sbjct: 921 LCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980
Query: 1161 RCDKCTRGYSGVFPDCTPCHQC 1182
RCD+C Y G P C C
Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPC 1002
Score = 172 bits (437), Expect = 2e-42
Identities = 100/315 (31%), Positives = 143/315 (45%), Gaps = 31/315 (9%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSV-NA 831
C+C+ GS++ C+P+ GQC+C+ G C+ C +G + CK C+C GS+
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806
Query: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCNGHADD-----CDPVTG 881
CN TGQC C V RQC++CL G++ C PC C+ C+ TG
Sbjct: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866
Query: 882 ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ 941
+C C+ G C +C Y + I + HC+ C C G C DP++ Q
Sbjct: 867 QC-PCKLGVTGLRCNQCEPHRY-NLTIDNFQHCQMCECDS---LGTLPGTIC--DPISGQ 919
Query: 942 LACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001
C+C P G RC+ C G++ +P G C PC CH C+ TG+C+
Sbjct: 920 --CLCVPNRQGRRCNQCQPGFYISPGNATG-CLPCSCHTTGAVN--HICNSLTGQCVCQD 974
Query: 1002 YHTEGEHCQFCRFGYYG-DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNV 1060
G+ C C+ Y+G D C+ C C+ G + E C+ TGQC C V
Sbjct: 975 ASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCH-------LVTGQCFCKQFV 1027
Query: 1061 IGQNCDRCAPNTWQL 1075
G CD C P+ L
Sbjct: 1028 TGSKCDACVPSASHL 1042
Score = 160 bits (404), Expect = 1e-38
Identities = 90/257 (35%), Positives = 122/257 (47%), Gaps = 30/257 (11%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C+ N GL C+ C + ++ N C+ C CN H F
Sbjct: 713 GQCKCKANVIGLRCDHC-----NFGFKFLRSFNDVGCEPCQCNLHGSVNKFC-------- 759
Query: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
N G C+ C+ G C+ C+ +Y D C+ C CD AGS +C++ T
Sbjct: 760 NPHSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAKT 812
Query: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
GQC CK NVEG C+ C EG + L + F C C C+ GTI G C+
Sbjct: 813 --------GQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864
Query: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDCDLGGALNNS-CFAESGQCSCRP 533
TG C CK VTG C+QC P + L+ D C+ C+CD G L + C SGQC C P
Sbjct: 865 TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924
Query: 534 HMIGRQCNEVEPGYYFA 550
+ GR+CN+ +PG+Y +
Sbjct: 925 NRQGRRCNQCQPGFYIS 941
Score = 148 bits (374), Expect = 4e-35
Identities = 85/258 (32%), Positives = 121/258 (46%), Gaps = 41/258 (15%)
Query: 296 GHCMCRHNTKGLNCELCMD--FYHDLPWRPAEGRNSNACKKCNCNEH-----SISCHFDM 348
G C+C+ N +G C C++ FY NS C CNC++ S+ C
Sbjct: 813 GQCICKPNVEGRQCNKCLEGNFY-------LRQNNSFLCLPCNCDKTGTINGSLLC---- 861
Query: 349 AVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE 408
N S G C C+ G C QC+P Y I + C+ C CD G+
Sbjct: 862 -------NKSTGQCP-CKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPG 910
Query: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPG 468
ICD I+GQC C N +G C+ C+ GFY +S + GC C+C+ G +
Sbjct: 911 TICDP--------ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAV-- 959
Query: 469 GNPCDSETGHCYCKRL-VTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESG 527
+ C+S TG C C+ + GQ CDQC ++G C+PC+C L GALN +C +G
Sbjct: 960 NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG 1019
Query: 528 QCSCRPHMIGRQCNEVEP 545
QC C+ + G +C+ P
Sbjct: 1020 QCFCKQFVTGSKCDACVP 1037
Score = 137 bits (344), Expect = 1e-31
Identities = 80/263 (30%), Positives = 123/263 (46%), Gaps = 46/263 (17%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C+ KGL C+ C + ++ G + CK C+C+ G
Sbjct: 764 GQCECKKEAKGLQCDTCRENFY--------GLDVTNCKACDCD--------------TAG 801
Query: 356 NVSGGVCDD------CQHNTMGRNCEQCKP--FYYQHPERDIRDPNFCERCTCDPAGSQN 407
++ G VC+ C+ N GR C +C FY + + C C CD G+ N
Sbjct: 802 SLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ-----NNSFLCLPCNCDKTGTIN 856
Query: 408 EGI-CDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTI 466
+ C+ T GQC CKL V G C+ C+ Y+L+ ++ C+ C C+ LGT+
Sbjct: 857 GSLLCNKST--------GQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908
Query: 467 PGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAES 526
PG CD +G C C G+ C+QC P + + GC PC C GA+N+ C + +
Sbjct: 909 PG-TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLT 967
Query: 527 GQCSCRPHMI-GRQCNEVEPGYY 548
GQC C+ I G++C++ + Y+
Sbjct: 968 GQCVCQDASIAGQRCDQCKDHYF 990
Score = 87.4 bits (215), Expect = 1e-16
Identities = 37/89 (41%), Positives = 54/89 (60%), Gaps = 3/89 (3%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRP-NVVGRTCNRCAPGTFGFGPSG--CKPCECHLQG 827
L C C G+++ +C+ GQC C+ ++ G+ C++C FGF P C+PC CHL G
Sbjct: 949 LPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSG 1008
Query: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLP 856
++N C+ VTGQC C Q V +CD C+P
Sbjct: 1009 ALNETCHLVTGQCFCKQFVTGSKCDACVP 1037
Score = 69.7 bits (169), Expect = 2e-11
Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 29/163 (17%)
Query: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
+ G C+C N +G C C ++ P N+ C C SCH AV
Sbjct: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC-------SCHTTGAVNHI 962
Query: 354 TGNVSGG-VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICD 412
+++G VC D + G+ C+QCK Y+ + R C+ C C +G+ NE
Sbjct: 963 CNSLTGQCVCQDA--SIAGQRCDQCKDHYFGFDPQTGR----CQPCNCHLSGALNE---- 1012
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGC 455
+ L+ GQC CK V G CD C L + GC
Sbjct: 1013 -----TCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 266 bits (680), Expect = 1e-70
Identities = 183/599 (30%), Positives = 279/599 (46%), Gaps = 99/599 (16%)
Query: 4 LQLLAFSFLALCRARVRAQEPEFSYGCAEG-SCYPATGDLLIGRAQKLSVTSTCGLH--- 59
L LL L C A R +P G A G S +P +L A ++ T+TCG
Sbjct: 21 LLLLVLRVLPACGATAR--DP----GAAAGLSLHPTYFNL--AEAARIWATATCGERGPG 72
Query: 60 ----KPEPYCIV---------SHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPN 106
+PE YC + H + + C CNS+DP +H + N + +
Sbjct: 73 EGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRK------AHPVTNAI-----D 121
Query: 107 RLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLIERSSDFGKTW 160
+ WWQS +G + V + LDL FH ++++ F RP ++ERS DFG T+
Sbjct: 122 GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTY 181
Query: 161 GVYRYFAY---DCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALD--PAFK 215
++YFA+ DC F + + + DD++C + YS I P GEV+ ++ P K
Sbjct: 182 SPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAK 241
Query: 216 IEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRME---IREKYYYAVYDMVVRGNCF 272
+S ++ K TN+R++F++ +TL +L+ + +YYY++ D+ + G C
Sbjct: 242 -NFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
Query: 273 CYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNAC 332
C GHA C N + C C+H+T G C+ C Y+ WRPA S+ C
Sbjct: 301 CNGHAEVC----NINNPEKLF---RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHEC 353
Query: 333 KKCNCNEHSISCHFDMAVYLATGNVS-------GGVCDDCQHNTMGRNCEQCKPFYYQHP 385
+ CNC+ H+ +C++D V +++ GGVC +CQHNT G NCEQC YY+
Sbjct: 354 EACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPY 413
Query: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
+ P+ C C+CDP + C+ +G+C CK N G++C+ C G+Y
Sbjct: 414 GVPVDAPDGCIPCSCDPEHADG---CEQG--------SGRCHCKPNFHGDNCEKCAIGYY 462
Query: 446 DL--------------SSEDPFG--CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQH 489
+ SSEDP K C CN G +P CD+ G C C+ V G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLP--EICDAH-GRCLCRPGVEGPR 519
Query: 490 CDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
CD C + C+ C C G+ C + +GQC CRP + G++C+ G Y
Sbjct: 520 CDTCRSGFYSFPI----CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY 574
Score = 175 bits (444), Expect = 3e-43
Identities = 130/448 (29%), Positives = 170/448 (37%), Gaps = 114/448 (25%)
Query: 821 CECHLQGSVNAFCNPVT-GQCHCFQGVYARQCDRCLPGH---------WGFP-SCQPCQC 869
C C+ V NP +C C CDRC G+ W C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 870 NGHADDC--DPVT----------------GECLNCQDYTMGHNCERCLAGYY---GDPII 908
+GHA +C DP G C+NCQ T G NCE+C GYY G P+
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPV- 417
Query: 909 GSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP- 966
+ D C PC C P+ D Q + C+ C P + G C+ CA GY+ P
Sbjct: 418 DAPDGCIPCSCDPEHADGCEQGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPF 466
Query: 967 ---------------SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
V G + C C N++ PE CD GRCL C EG C
Sbjct: 467 CLRIPIFPVSTPSSEDPVAGDIKGCDC--NLEGVLPEICDAH-GRCL-CRPGVEGPRCDT 522
Query: 1012 CRFGYYGDALQQDCRKCVCNYLGTVQ-------------------------------EHC 1040
CR G+Y + C+ C C+ LG+ Q HC
Sbjct: 523 CRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579
Query: 1041 NGSDCQCDKA------TGQCLCLPNVIGQNCDRCAPNTWQL--ASGTGCDPCNCNAAHSF 1092
GS CD A G C C +V G C RC W L + +GC C C+ A +
Sbjct: 580 QGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV 639
Query: 1093 GPS--CNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE---CRACDCDPRGIETPQCDQS 1147
+ C + G C C GG +C C++ ++ C+ C CD G + C
Sbjct: 640 SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGP 699
Query: 1148 TGQCVCVEGVEGPRCDKCTRGYSGVFPD 1175
+G C C E V G C + Y FPD
Sbjct: 700 SGVCQCREHVVGKVCQRPENNY--YFPD 725
Score = 168 bits (425), Expect = 5e-41
Identities = 89/276 (32%), Positives = 127/276 (46%), Gaps = 43/276 (15%)
Query: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
HG C+CR +G C+ C ++ P C+ C C S + M T
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWC---SALGSYQMPCSSVT 552
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCT--CDPAGSQNEGICD 412
G +C+ G+ C++C Y P C+ + CDPAG+ N +
Sbjct: 553 GQC------ECRPGVTGQRCDRCLSGAYDFPH--------CQGSSSACDPAGTINSNL-- 596
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPC 472
G C+CKL+VEG C CK +++L E+P GC C C+ GT+ G C
Sbjct: 597 -----------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGEC 645
Query: 473 DSETGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSC 531
G C+CK V G CD C ++ L ++ GC+ C CD+GGAL++ C SG C C
Sbjct: 646 RQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQC 705
Query: 532 RPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPG 567
R H++G+ C E YYF L H YE E+ + G
Sbjct: 706 REHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 147 bits (370), Expect = 1e-34
Identities = 85/238 (35%), Positives = 104/238 (43%), Gaps = 23/238 (9%)
Query: 796 PNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCL 855
P R C A F G PCECH G+ C+P GQC C V RQC RC
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 856 PGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYG-DPIIGSGDHC 914
GH+GFP C+PC C C+ +TG+C C T+ CE C + P+ G C
Sbjct: 1301 TGHYGFPRCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----C 1353
Query: 915 RPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ 974
C C S R + + C C P G +CD CASG++ P C
Sbjct: 1354 EGCNC-----SRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP-----ECV 1403
Query: 975 PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFG--YYGDALQQDCRKCVC 1030
PC C N D T+P CD TG CL C + EG C CR G + A + C C C
Sbjct: 1404 PCNC--NRDGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 145 bits (367), Expect = 3e-34
Identities = 95/324 (29%), Positives = 135/324 (41%), Gaps = 58/324 (17%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF------------GPSG- 817
+ C CDP+ + C+ G+C C+PN G C +CA G + F PS
Sbjct: 424 IPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
Query: 818 ------CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN- 870
K C+C+L+G + C+ G+C C GV +CD C G + FP CQ C C+
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
Query: 871 --GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDP-IIGSGDHCRPCPCPDGPDSGR 927
+ C VTG+C C+ G C+RCL+G Y P GS C P +G
Sbjct: 541 LGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDP--------AGT 591
Query: 928 QFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDP 987
+ Y C C G C C Y+ E C C+CH +
Sbjct: 592 INSNLGY---------CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
Query: 988 EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGS 1043
C + G C C H G+ C C GY+ AL++ C+ C C+ G + C+G
Sbjct: 643 GECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGCQCDIGGALSSMCSG- 698
Query: 1044 DCQCDKATGQCLCLPNVIGQNCDR 1067
+G C C +V+G+ C R
Sbjct: 699 ------PSGVCQCREHVVGKVCQR 716
Score = 143 bits (361), Expect = 1e-33
Identities = 86/251 (34%), Positives = 115/251 (45%), Gaps = 35/251 (13%)
Query: 739 CLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNV 798
C +NS + + C+N S+ A H+ L CEC P G+ C P GGQC C+PNV
Sbjct: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
Query: 799 VGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
+GR C RCA G +GF CKPC C C +TGQC C QC+ C
Sbjct: 1292 IGRQCTRCATGHYGF--PRCKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHS 1344
Query: 859 WGF---PSCQPCQCNGHA------DDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIG 909
+ F C+ C C+ +CD +G+C C+ G C+RC +G+Y P
Sbjct: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP--- 1400
Query: 910 SGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFG-NPS 967
C PC C DG + G DP T AC+C G+ C+ C G F +P+
Sbjct: 1401 ---ECVPCNCNRDGTEPG-------VCDPGT--GACLCKENVEGTECNVCREGSFHLDPA 1448
Query: 968 EVGGSCQPCQC 978
+ G C C C
Sbjct: 1449 NLKG-CTSCFC 1458
Score = 138 bits (348), Expect = 4e-32
Identities = 69/165 (41%), Positives = 88/165 (53%), Gaps = 18/165 (10%)
Query: 840 CHCFQGVYARQCDRCLPG----HWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
C C C C PG H G + C PC CNGH++ C +G C+NCQ T G
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGS 953
+CERC GYYG+ + GS CR CPCP FA C + ++ C C GY G+
Sbjct: 1714 HCERCQEGYYGNAVHGS---CRACPCP----HTNSFATGCVVNGGDVR--CSCKAGYTGT 1764
Query: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCL 998
+C+ CA GYFGNP + GGSCQPC C++N +C TG C+
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 132 bits (333), Expect = 2e-30
Identities = 89/253 (35%), Positives = 110/253 (43%), Gaps = 29/253 (11%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
C+C+ +G L +CD +G +C CRP V G C+ C G + F C+ C C GS
Sbjct: 491 CDCNLEGVLPEICDAHG-RCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQMP 547
Query: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV------TGECLNC 886
C+ VTGQC C GV ++CDRCL G + FP CQ G + CDP G C C
Sbjct: 548 CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQ-----GSSSACDPAGTINSNLGYC-QC 601
Query: 887 QDYTMGHNCERCLAGYYG-DPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLAC 944
+ + G C RC Y+ D SG C C C G SG R D C
Sbjct: 602 KLHVEGPTCSRCKLLYWNLDKENPSG--CSECKCHKAGTVSGTGECRQGDGD-------C 652
Query: 945 VCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
C G CD C GYF CQ CQC +I C +G C +C H
Sbjct: 653 HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHV 709
Query: 1005 EGEHCQFCRFGYY 1017
G+ CQ YY
Sbjct: 710 VGKVCQRPENNYY 722
Score = 131 bits (329), Expect = 7e-30
Identities = 82/261 (31%), Positives = 113/261 (43%), Gaps = 38/261 (14%)
Query: 975 PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLG 1034
PC+CH T P C E G+C C + G C C G+YG C+ C C
Sbjct: 1265 PCECHPT-GATGPH-CSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR---CKPCSCGRR- 1317
Query: 1035 TVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFG- 1093
C++ TGQC C P + C+ C +++ GC+ CNC+ +
Sbjct: 1318 -----------LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEA 1366
Query: 1094 --PSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQC 1151
P C+ +GQC+C P GR C C F+ P EC C+C+ G E CD TG C
Sbjct: 1367 AMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTGAC 1424
Query: 1152 VCVEGVEGPRCDKCTRGYSGVFP----DCTPCHQCFALWDVIIAELTNRTHRFLEKAKAL 1207
+C E VEG C+ C G + P CT C CF + N+ H +
Sbjct: 1425 LCKENVEGTECNVCREGSFHLDPANLKGCTSCF-CFG--------VNNQCHS--SHKRRT 1473
Query: 1208 KISGVIGPYRETVDSVERKVS 1228
K ++G + ET D V+ VS
Sbjct: 1474 KFVDMLGWHLETADRVDIPVS 1494
Score = 129 bits (323), Expect = 3e-29
Identities = 172/836 (20%), Positives = 317/836 (37%), Gaps = 137/836 (16%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPSEV-GGSCQPCQCHNNIDTTDPEACDKETGRCLKCLY 1002
C C P Y G C C+ GY+ + + G C PC C+ + + C +G C+ C +
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ-----CQDGSGICVNCQH 1708
Query: 1003 HTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC--NGSDCQCDKATGQCLCLPNV 1060
+T GEHC+ C+ GYYG+A+ CR C C + + C NG D +C C
Sbjct: 1709 NTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCS-------CKAGY 1761
Query: 1061 IGQNCDRCAPNTW--QLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118
G C+RCAP + G C PC+CN+ G SC+ TG C Q
Sbjct: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC------------INQ 1808
Query: 1119 ELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTP 1178
E P EC CD C + + G + +G S
Sbjct: 1809 EPKDSSPAEECDDCD---------SCVMTLLNDLATMGEQLRLVKSQLQGLSA------- 1852
Query: 1179 CHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSP 1238
A L + +AK L+ + YR + + K+ ++
Sbjct: 1853 -----------SAGLLEQMRHMETQAKDLR--NQLLNYRSAISNHGSKIEGLE------- 1892
Query: 1239 AAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNT 1298
+ + +L +E E L ++ ++ ++ L++ +++ +AKELD + N
Sbjct: 1893 -----RELTDLNQEFETL-QEKAQVNSRKAQTLNNNVNRATQSAKELD------VKIKNV 1940
Query: 1299 VKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERV--------NASTTEPNSTVEQSA 1350
++ + L+ I +D G + + EA+ + E + +S
Sbjct: 1941 IRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQ 2000
Query: 1351 LMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE 1410
L+ +R+ + + L+E KL DL A + A+ +
Sbjct: 2001 LLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLS--DLRARLQ-------EAAAQAKQ 2051
Query: 1411 CGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKL 1470
G N E ER G ++ L D L + + A
Sbjct: 2052 ANGLN---QENERALG---------AIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQ 2099
Query: 1471 RADEAKQSAEDILLKTN-ATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVL 1529
+++++ E + N A +E DK E R+ K + + + S++ +A ++
Sbjct: 2100 LMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGK--TSLVEEAEKHARSLQELAKQLE 2157
Query: 1530 KMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVK 1589
+++ ++ +L +R V++ + E IL I AE A AS+SA
Sbjct: 2158 EIKRNASGDEL------VRCAVDAATAYENILN----AIKAAEDAANRAASASESALQTV 2207
Query: 1590 VTADMVKEA----------LEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEE 1639
+ D+ ++A L EA+ Q ++ + A ++Q T N++T + +
Sbjct: 2208 IKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLT 2267
Query: 1640 TLFNASQRI--SELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEK 1697
TL + I +++ + K + + + + + ++ E +K T +E
Sbjct: 2268 TLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNED 2327
Query: 1698 YKK----VENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYED 1749
+KK +N + K T + D RK E + N+ L + + +++L ++ D
Sbjct: 2328 FKKALTDADNSVNKLTNKLPDLWRKIESI-NQQLLPLGNISDNMDRIRELIQQARD 2382
Score = 122 bits (306), Expect = 3e-27
Identities = 83/275 (30%), Positives = 116/275 (42%), Gaps = 56/275 (20%)
Query: 944 CVCDPGYIGSRCDDCASGYFGN---PS--EVGGSCQPCQCHNNIDTT--DPEACDKET-- 994
C C G CD C +GY P+ E C+ C CH + DP+ ++
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 995 ---------GRCLKCLYHTEGEHCQFCRFGYYG------DALQQDCRKCVCNYLGTVQEH 1039
G C+ C ++T G +C+ C GYY DA C C C+ EH
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDA-PDGCIPCSCD-----PEH 432
Query: 1040 CNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ-----------LASGTGCDP----- 1083
+G C++ +G+C C PN G NC++CA + +++ + DP
Sbjct: 433 ADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI 488
Query: 1084 --CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIET 1141
C+CN C+ G+C C PG G C C+ F+ P C+AC C G
Sbjct: 489 KGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQ 545
Query: 1142 PQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDC 1176
C TGQC C GV G RCD+C G + FP C
Sbjct: 546 MPCSSVTGQCECRPGVTGQRCDRCLSG-AYDFPHC 579
Score = 103 bits (258), Expect = 1e-21
Identities = 58/191 (30%), Positives = 84/191 (43%), Gaps = 30/191 (15%)
Query: 359 GGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFS 418
GG C CQ N +GR C +C +Y P C+ C+C +C+ T
Sbjct: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFPR--------CKPCSC------GRRLCEEMT--- 1323
Query: 419 TGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP-CDSETG 477
GQCRC C+VC+ + S GC+ C C+ GTI P CD ++G
Sbjct: 1324 -----GQCRCPPRTVRPQCEVCET--HSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG 1376
Query: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
C CK +TG+ CD+C + C PC+C+ G C +G C C+ ++ G
Sbjct: 1377 QCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1432
Query: 538 RQCNEVEPGYY 548
+CN G +
Sbjct: 1433 TECNVCREGSF 1443
Score = 93.2 bits (230), Expect = 2e-18
Identities = 69/241 (28%), Positives = 99/241 (41%), Gaps = 45/241 (18%)
Query: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
V G C CR G C+ C+ +D P +C S +C D A
Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFP---------------HCQGSSSAC--DPA---G 590
Query: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGS-QNEGICD 412
T N + G C C+ + G C +CK Y+ D +P+ C C C AG+ G C
Sbjct: 591 TINSNLGYC-QCKLHVEGPTCSRCKLLYW---NLDKENPSGCSECKCHKAGTVSGTGECR 646
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPC 472
G C CK +V G+ CD C++G++ L + FGC+ C C+ G + + C
Sbjct: 647 QGD--------GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGAL--SSMC 696
Query: 473 DSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL--------DGCRPCDCDLGGALNNSCFA 524
+G C C+ V G+ C + PE+ DL DG P DL + F
Sbjct: 697 SGPSGVCQCREHVVGKVCQR--PENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFP 754
Query: 525 E 525
E
Sbjct: 755 E 755
Score = 92.8 bits (229), Expect = 3e-18
Identities = 69/229 (30%), Positives = 86/229 (37%), Gaps = 48/229 (20%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C+ N G C C ++ P CK C+C +M
Sbjct: 1283 GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE---EMT------ 1323
Query: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQ-HPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
G C C T+ CE C+ + HP CE C C G+ + +
Sbjct: 1324 ----GQCR-CPPRTVRPQCEVCETHSFSFHPMAG------CEGCNCSRRGTIEAAMPECD 1372
Query: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
D +GQCRCK + G CD C GFY C C CN GT PG CD
Sbjct: 1373 RD------SGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNRDGTEPG--VCDP 1419
Query: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLS-NDLDGCRPCDCDLGGALNNSC 522
TG C CK V G C+ C + L +L GC C C +NN C
Sbjct: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC---FGVNNQC 1465
Score = 90.1 bits (222), Expect = 2e-17
Identities = 62/223 (27%), Positives = 83/223 (37%), Gaps = 65/223 (29%)
Query: 738 RCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPN 797
RCL R V+ P D CR+ +S AC C GS C GQC+CRP
Sbjct: 508 RCL--CRPGVEGPRCDTCRSGFYSFPICQ-----ACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 798 VVGRTCNRCAPGTFGF-------------------------------------------- 813
V G+ C+RC G + F
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
Query: 814 ---GPSGCKPCECHLQGSVNAF--CNPVTGQCHCFQGVYARQCDRCLPGHW-----GFPS 863
PSGC C+CH G+V+ C G CHC V CD C G++ +
Sbjct: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680
Query: 864 CQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCERCLAGYY 903
CQ CQC+ + C +G C C+++ +G C+R YY
Sbjct: 681 CQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722
Score = 89.4 bits (220), Expect = 3e-17
Identities = 57/211 (27%), Positives = 82/211 (38%), Gaps = 35/211 (16%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C C G +C+ C Y+ R +G + C CNCN HS C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
Query: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
G+C +CQHNT G +CE+C+ YY + C C C S F
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNS-----------F 1742
Query: 418 STGLIAG----QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
+TG + +C CK G C+ C G++ + C+ C+CN G + +P
Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 1802
Query: 474 SETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
+ + K + CD C L NDL
Sbjct: 1803 GDCINQEPKDSSPAEECDDCDSCVMTLLNDL 1833
Score = 88.6 bits (218), Expect = 5e-17
Identities = 51/143 (35%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Query: 769 TGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQ 826
TG C+ G S+ C G C C+ N G C RC G +G G C+ C C
Sbjct: 1681 TGRCVPCNCNGH-SNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHT 1739
Query: 827 GSVNAFC--NPVTGQCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQC--NGHADDCD 877
S C N +C C G QC+RC PG++G P SCQPC C NG C
Sbjct: 1740 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCH 1799
Query: 878 PVTGECLNCQ--DYTMGHNCERC 898
P+TG+C+N + D + C+ C
Sbjct: 1800 PLTGDCINQEPKDSSPAEECDDC 1822
Score = 81.3 bits (199), Expect = 8e-15
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 25/154 (16%)
Query: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
C C P G+ GQC C+ NV G C C G Y CK
Sbjct: 1266 CECHPTGATGPHCSPE---------GGQCPCQPNVIGRQCTRCATGHYGFPR-----CKP 1311
Query: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
C+C G C+ TG C C C+ C + + + GC C+C G
Sbjct: 1312 CSC-------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSF-HPMAGCEGCNCSRRGT 1363
Query: 518 LNNS---CFAESGQCSCRPHMIGRQCNEVEPGYY 548
+ + C +SGQC C+P + GRQC+ G+Y
Sbjct: 1364 IEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY 1397
Score = 79.3 bits (194), Expect = 3e-14
Identities = 50/171 (29%), Positives = 71/171 (41%), Gaps = 27/171 (15%)
Query: 365 CQHNTMGRNCEQCKPFYYQHPERDIRD--PNFCERCTCDPAGSQ---NEGICDSYTDFST 419
C G +C+ C P YY RD + C C C+ +Q GIC
Sbjct: 1656 CPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGIC-------- 1703
Query: 420 GLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC 479
C+ N GEHC+ C+EG+Y + C++C C + G + C
Sbjct: 1704 ------VNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRC 1755
Query: 480 YCKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQC 529
CK TG C++C P ++G G C+PC C+ G L SC +G C
Sbjct: 1756 SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDC 1805
Score = 78.6 bits (192), Expect = 5e-14
Identities = 59/199 (29%), Positives = 80/199 (40%), Gaps = 35/199 (17%)
Query: 792 CQCRPNVVGRTCNRCAPGTF----GFGPSGCKPCECHLQGSVNAFCNPVTGQC-HCFQGV 846
C C P G +C C+PG + G C PC C+ G N C +G C +C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNT 1710
Query: 847 YARQCDRCLPGHWG---FPSCQPCQC---NGHADDCDPVTGEC-LNCQDYTMGHNCERCL 899
C+RC G++G SC+ C C N A C G+ +C+ G CERC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 900 AGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCY--------QDPVTLQLACVCDPGYI 951
GY+G+P G C+PC C G SC+ Q+P A CD
Sbjct: 1771 PGYFGNP-QKFGGSCQPCSCNSNGQLG-----SCHPLTGDCINQEPKDSSPAEECDD--- 1821
Query: 952 GSRCDDCASGYFGNPSEVG 970
CD C + + +G
Sbjct: 1822 ---CDSCVMTLLNDLATMG 1837
Score = 75.1 bits (183), Expect = 6e-13
Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 46/146 (31%)
Query: 1080 GCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE----------- 1128
G PC C+ + GP C+ GQC C P GR C+ C +G P +
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEE 1321
Query: 1129 -------------------------------CRACDCDPRG-IET--PQCDQSTGQCVCV 1154
C C+C RG IE P+CD+ +GQC C
Sbjct: 1322 MTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCK 1381
Query: 1155 EGVEGPRCDKCTRGYSGVFPDCTPCH 1180
+ G +CD+C G+ FP+C PC+
Sbjct: 1382 PRITGRQCDRCASGFYR-FPECVPCN 1406
Score = 68.6 bits (166), Expect = 5e-11
Identities = 38/127 (29%), Positives = 53/127 (41%), Gaps = 10/127 (7%)
Query: 426 CRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKRL 484
C C G+ C C G+Y D G + C P N C +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHN 1709
Query: 485 VTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESG--QCSCRPHMIGRQCN 541
G+HC++C ++G N + G CR C C + C G +CSC+ G QC
Sbjct: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
Query: 542 EVEPGYY 548
PGY+
Sbjct: 1768 RCAPGYF 1774
Score = 67.4 bits (163), Expect = 1e-10
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 766 LHQTGLACECDPQGSLSSVCDPNGG--QCQCRPNVVGRTCNRCAPGTFG----FGPSGCK 819
+H + AC C S ++ C NGG +C C+ G C RCAPG FG FG S C+
Sbjct: 1727 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS-CQ 1785
Query: 820 PCECHLQGSVNAFCNPVTGQC---HCFQGVYARQCDRC 854
PC C+ G + + C+P+TG C A +CD C
Sbjct: 1786 PCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 60.5 bits (145), Expect = 1e-08
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
C C+ G+ VCDP G C C+ NV G CN C G+F P+ +L+G + F
Sbjct: 1405 CNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPA-------NLKGCTSCF 1457
Query: 833 CNPVTGQCH 841
C V QCH
Sbjct: 1458 CFGVNNQCH 1466
Score = 58.2 bits (139), Expect = 7e-08
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 49/191 (25%)
Query: 259 YYAVYDMVVRGNCF---CYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMD 314
YY + + G C C GH+++C DG G C+ C+HNT G +CE C +
Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQ--DG---------SGICVNCQHNTAGEHCERCQE 1720
Query: 315 FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV--SGGVCDDCQHNTMGR 372
Y+ +C+ C C H+ S ATG V G V C+ G
Sbjct: 1721 GYYG-------NAVHGSCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 1764
Query: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC---RCK 429
CE+C P Y+ +P+ + C+ C+C+ G G C T G C K
Sbjct: 1765 QCERCAPGYFGNPQ---KFGGSCQPCSCNSNGQL--GSCHPLT--------GDCINQEPK 1811
Query: 430 LNVEGEHCDVC 440
+ E CD C
Sbjct: 1812 DSSPAEECDDC 1822
Score = 51.2 bits (121), Expect = 9e-06
Identities = 20/43 (46%), Positives = 25/43 (58%)
Query: 506 GCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
G PC+C GA C E GQC C+P++IGRQC G+Y
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY 1304
Score = 40.8 bits (94), Expect = 0.012
Identities = 64/343 (18%), Positives = 143/343 (41%), Gaps = 49/343 (14%)
Query: 1446 DLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIK 1505
D D V++ L ++ + + + K + SA LL+ M+ ++LRN +
Sbjct: 1821 DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAG--LLEQ---MRHMETQAKDLRNQLL 1875
Query: 1506 QIRNFLTQDSADLDSIEAVAN------EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEV 1559
R+ ++ + ++ +E E L+ + ++ Q L ++ +S +++V
Sbjct: 1876 NYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDV 1935
Query: 1560 ILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAE----KAIKQ 1615
+++ I +LL++ +V + D +E E + K +++
Sbjct: 1936 KIKNV---IRNVHILLKQISGTDGEGNNVP-SGDFSREWAEAQRMMRELRNRNFGKHLRE 1991
Query: 1616 ADEDIQGTQNLLTSIES--ETAASEETLFNASQR--ISELERNVEELKRKAAQNSGEAEY 1671
A+ D + +Q LL I + +T E S R ++E E + +L+ + + + +A
Sbjct: 1992 AEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQA-- 2049
Query: 1672 IEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLA 1731
K +G L+++ ++ I ++ +E + A + L
Sbjct: 2050 ----------------KQANG-LNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLL 2092
Query: 1732 QANSKLQLLKDLERKYE-------DNQRYLEDKAQELARLEGE 1767
Q N LQL++ +++YE + ++ L DK +EL+R G+
Sbjct: 2093 QTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGK 2135
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 9/71 (12%)
Query: 279 ECAPV----DGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK 334
EC P DG V G C+C+ N +G C +C + L + N C
Sbjct: 1401 ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL-----DPANLKGCTS 1455
Query: 335 CNCNEHSISCH 345
C C + CH
Sbjct: 1456 CFCFGVNNQCH 1466
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 266 bits (680), Expect = 1e-70
Identities = 183/599 (30%), Positives = 279/599 (46%), Gaps = 99/599 (16%)
Query: 4 LQLLAFSFLALCRARVRAQEPEFSYGCAEG-SCYPATGDLLIGRAQKLSVTSTCGLH--- 59
L LL L C A R +P G A G S +P +L A ++ T+TCG
Sbjct: 21 LLLLVLRVLPACGATAR--DP----GAAAGLSLHPTYFNL--AEAARIWATATCGERGPG 72
Query: 60 ----KPEPYCIV---------SHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPN 106
+PE YC + H + + C CNS+DP +H + N + +
Sbjct: 73 EGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRK------AHPVTNAI-----D 121
Query: 107 RLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLIERSSDFGKTW 160
+ WWQS +G + V + LDL FH ++++ F RP ++ERS DFG T+
Sbjct: 122 GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTY 181
Query: 161 GVYRYFAY---DCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALD--PAFK 215
++YFA+ DC F + + + DD++C + YS I P GEV+ ++ P K
Sbjct: 182 SPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAK 241
Query: 216 IEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRME---IREKYYYAVYDMVVRGNCF 272
+S ++ K TN+R++F++ +TL +L+ + +YYY++ D+ + G C
Sbjct: 242 -NFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
Query: 273 CYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNAC 332
C GHA C N + C C+H+T G C+ C Y+ WRPA S+ C
Sbjct: 301 CNGHAEVC----NINNPEKLF---RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHEC 353
Query: 333 KKCNCNEHSISCHFDMAVYLATGNVS-------GGVCDDCQHNTMGRNCEQCKPFYYQHP 385
+ CNC+ H+ +C++D V +++ GGVC +CQHNT G NCEQC YY+
Sbjct: 354 EACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPY 413
Query: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
+ P+ C C+CDP + C+ +G+C CK N G++C+ C G+Y
Sbjct: 414 GVPVDAPDGCIPCSCDPEHADG---CEQG--------SGRCHCKPNFHGDNCEKCAIGYY 462
Query: 446 DL--------------SSEDPFG--CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQH 489
+ SSEDP K C CN G +P CD+ G C C+ V G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLP--EICDAH-GRCLCRPGVEGPR 519
Query: 490 CDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
CD C + C+ C C G+ C + +GQC CRP + G++C+ G Y
Sbjct: 520 CDTCRSGFYSFPI----CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY 574
Score = 175 bits (444), Expect = 3e-43
Identities = 130/448 (29%), Positives = 170/448 (37%), Gaps = 114/448 (25%)
Query: 821 CECHLQGSVNAFCNPVT-GQCHCFQGVYARQCDRCLPGH---------WGFP-SCQPCQC 869
C C+ V NP +C C CDRC G+ W C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 870 NGHADDC--DPVT----------------GECLNCQDYTMGHNCERCLAGYY---GDPII 908
+GHA +C DP G C+NCQ T G NCE+C GYY G P+
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPV- 417
Query: 909 GSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP- 966
+ D C PC C P+ D Q + C+ C P + G C+ CA GY+ P
Sbjct: 418 DAPDGCIPCSCDPEHADGCEQGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPF 466
Query: 967 ---------------SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
V G + C C N++ PE CD GRCL C EG C
Sbjct: 467 CLRIPIFPVSTPSSEDPVAGDIKGCDC--NLEGVLPEICDAH-GRCL-CRPGVEGPRCDT 522
Query: 1012 CRFGYYGDALQQDCRKCVCNYLGTVQ-------------------------------EHC 1040
CR G+Y + C+ C C+ LG+ Q HC
Sbjct: 523 CRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579
Query: 1041 NGSDCQCDKA------TGQCLCLPNVIGQNCDRCAPNTWQL--ASGTGCDPCNCNAAHSF 1092
GS CD A G C C +V G C RC W L + +GC C C+ A +
Sbjct: 580 QGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV 639
Query: 1093 GPS--CNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE---CRACDCDPRGIETPQCDQS 1147
+ C + G C C GG +C C++ ++ C+ C CD G + C
Sbjct: 640 SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGP 699
Query: 1148 TGQCVCVEGVEGPRCDKCTRGYSGVFPD 1175
+G C C E V G C + Y FPD
Sbjct: 700 SGVCQCREHVVGKVCQRPENNY--YFPD 725
Score = 168 bits (425), Expect = 5e-41
Identities = 89/276 (32%), Positives = 127/276 (46%), Gaps = 43/276 (15%)
Query: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
HG C+CR +G C+ C ++ P C+ C C S + M T
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWC---SALGSYQMPCSSVT 552
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCT--CDPAGSQNEGICD 412
G +C+ G+ C++C Y P C+ + CDPAG+ N +
Sbjct: 553 GQC------ECRPGVTGQRCDRCLSGAYDFPH--------CQGSSSACDPAGTINSNL-- 596
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPC 472
G C+CKL+VEG C CK +++L E+P GC C C+ GT+ G C
Sbjct: 597 -----------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGEC 645
Query: 473 DSETGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSC 531
G C+CK V G CD C ++ L ++ GC+ C CD+GGAL++ C SG C C
Sbjct: 646 RQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQC 705
Query: 532 RPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPG 567
R H++G+ C E YYF L H YE E+ + G
Sbjct: 706 REHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 147 bits (370), Expect = 1e-34
Identities = 85/238 (35%), Positives = 104/238 (43%), Gaps = 23/238 (9%)
Query: 796 PNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCL 855
P R C A F G PCECH G+ C+P GQC C V RQC RC
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 856 PGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYG-DPIIGSGDHC 914
GH+GFP C+PC C C+ +TG+C C T+ CE C + P+ G C
Sbjct: 1301 TGHYGFPRCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----C 1353
Query: 915 RPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ 974
C C S R + + C C P G +CD CASG++ P C
Sbjct: 1354 EGCNC-----SRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP-----ECV 1403
Query: 975 PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFG--YYGDALQQDCRKCVC 1030
PC C N D T+P CD TG CL C + EG C CR G + A + C C C
Sbjct: 1404 PCNC--NRDGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 145 bits (367), Expect = 3e-34
Identities = 95/324 (29%), Positives = 135/324 (41%), Gaps = 58/324 (17%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF------------GPSG- 817
+ C CDP+ + C+ G+C C+PN G C +CA G + F PS
Sbjct: 424 IPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
Query: 818 ------CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN- 870
K C+C+L+G + C+ G+C C GV +CD C G + FP CQ C C+
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
Query: 871 --GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDP-IIGSGDHCRPCPCPDGPDSGR 927
+ C VTG+C C+ G C+RCL+G Y P GS C P +G
Sbjct: 541 LGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDP--------AGT 591
Query: 928 QFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDP 987
+ Y C C G C C Y+ E C C+CH +
Sbjct: 592 INSNLGY---------CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
Query: 988 EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGS 1043
C + G C C H G+ C C GY+ AL++ C+ C C+ G + C+G
Sbjct: 643 GECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGCQCDIGGALSSMCSG- 698
Query: 1044 DCQCDKATGQCLCLPNVIGQNCDR 1067
+G C C +V+G+ C R
Sbjct: 699 ------PSGVCQCREHVVGKVCQR 716
Score = 143 bits (361), Expect = 1e-33
Identities = 86/251 (34%), Positives = 115/251 (45%), Gaps = 35/251 (13%)
Query: 739 CLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNV 798
C +NS + + C+N S+ A H+ L CEC P G+ C P GGQC C+PNV
Sbjct: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
Query: 799 VGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
+GR C RCA G +GF CKPC C C +TGQC C QC+ C
Sbjct: 1292 IGRQCTRCATGHYGF--PRCKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHS 1344
Query: 859 WGF---PSCQPCQCNGHA------DDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIG 909
+ F C+ C C+ +CD +G+C C+ G C+RC +G+Y P
Sbjct: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP--- 1400
Query: 910 SGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFG-NPS 967
C PC C DG + G DP T AC+C G+ C+ C G F +P+
Sbjct: 1401 ---ECVPCNCNRDGTEPG-------VCDPGT--GACLCKENVEGTECNVCREGSFHLDPA 1448
Query: 968 EVGGSCQPCQC 978
+ G C C C
Sbjct: 1449 NLKG-CTSCFC 1458
Score = 138 bits (348), Expect = 4e-32
Identities = 69/165 (41%), Positives = 88/165 (53%), Gaps = 18/165 (10%)
Query: 840 CHCFQGVYARQCDRCLPG----HWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
C C C C PG H G + C PC CNGH++ C +G C+NCQ T G
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGS 953
+CERC GYYG+ + GS CR CPCP FA C + ++ C C GY G+
Sbjct: 1714 HCERCQEGYYGNAVHGS---CRACPCP----HTNSFATGCVVNGGDVR--CSCKAGYTGT 1764
Query: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCL 998
+C+ CA GYFGNP + GGSCQPC C++N +C TG C+
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 132 bits (333), Expect = 2e-30
Identities = 89/253 (35%), Positives = 110/253 (43%), Gaps = 29/253 (11%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
C+C+ +G L +CD +G +C CRP V G C+ C G + F C+ C C GS
Sbjct: 491 CDCNLEGVLPEICDAHG-RCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQMP 547
Query: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV------TGECLNC 886
C+ VTGQC C GV ++CDRCL G + FP CQ G + CDP G C C
Sbjct: 548 CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQ-----GSSSACDPAGTINSNLGYC-QC 601
Query: 887 QDYTMGHNCERCLAGYYG-DPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLAC 944
+ + G C RC Y+ D SG C C C G SG R D C
Sbjct: 602 KLHVEGPTCSRCKLLYWNLDKENPSG--CSECKCHKAGTVSGTGECRQGDGD-------C 652
Query: 945 VCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
C G CD C GYF CQ CQC +I C +G C +C H
Sbjct: 653 HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHV 709
Query: 1005 EGEHCQFCRFGYY 1017
G+ CQ YY
Sbjct: 710 VGKVCQRPENNYY 722
Score = 131 bits (329), Expect = 7e-30
Identities = 82/261 (31%), Positives = 113/261 (43%), Gaps = 38/261 (14%)
Query: 975 PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLG 1034
PC+CH T P C E G+C C + G C C G+YG C+ C C
Sbjct: 1265 PCECHPT-GATGPH-CSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR---CKPCSCGRR- 1317
Query: 1035 TVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFG- 1093
C++ TGQC C P + C+ C +++ GC+ CNC+ +
Sbjct: 1318 -----------LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEA 1366
Query: 1094 --PSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQC 1151
P C+ +GQC+C P GR C C F+ P EC C+C+ G E CD TG C
Sbjct: 1367 AMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTGAC 1424
Query: 1152 VCVEGVEGPRCDKCTRGYSGVFP----DCTPCHQCFALWDVIIAELTNRTHRFLEKAKAL 1207
+C E VEG C+ C G + P CT C CF + N+ H +
Sbjct: 1425 LCKENVEGTECNVCREGSFHLDPANLKGCTSCF-CFG--------VNNQCHS--SHKRRT 1473
Query: 1208 KISGVIGPYRETVDSVERKVS 1228
K ++G + ET D V+ VS
Sbjct: 1474 KFVDMLGWHLETADRVDIPVS 1494
Score = 122 bits (306), Expect = 3e-27
Identities = 83/275 (30%), Positives = 116/275 (42%), Gaps = 56/275 (20%)
Query: 944 CVCDPGYIGSRCDDCASGYFGN---PS--EVGGSCQPCQCHNNIDTT--DPEACDKET-- 994
C C G CD C +GY P+ E C+ C CH + DP+ ++
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 995 ---------GRCLKCLYHTEGEHCQFCRFGYYG------DALQQDCRKCVCNYLGTVQEH 1039
G C+ C ++T G +C+ C GYY DA C C C+ EH
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDA-PDGCIPCSCD-----PEH 432
Query: 1040 CNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ-----------LASGTGCDP----- 1083
+G C++ +G+C C PN G NC++CA + +++ + DP
Sbjct: 433 ADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI 488
Query: 1084 --CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIET 1141
C+CN C+ G+C C PG G C C+ F+ P C+AC C G
Sbjct: 489 KGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQ 545
Query: 1142 PQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDC 1176
C TGQC C GV G RCD+C G + FP C
Sbjct: 546 MPCSSVTGQCECRPGVTGQRCDRCLSG-AYDFPHC 579
Score = 121 bits (303), Expect = 7e-27
Identities = 154/763 (20%), Positives = 296/763 (38%), Gaps = 128/763 (16%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPSEV-GGSCQPCQCHNNIDTTDPEACDKETGRCLKCLY 1002
C C P Y G C C+ GY+ + + G C PC C+ + + C +G C+ C +
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ-----CQDGSGICVNCQH 1708
Query: 1003 HTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC--NGSDCQCDKATGQCLCLPNV 1060
+T GEHC+ C+ GYYG+A+ CR C C + + C NG D +C C
Sbjct: 1709 NTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCS-------CKAGY 1761
Query: 1061 IGQNCDRCAPNTW--QLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118
G C+RCAP + G C PC+CN+ G SC+ TG C Q
Sbjct: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC------------INQ 1808
Query: 1119 ELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTP 1178
E P EC CD C + + G + +G S
Sbjct: 1809 EPKDSSPAEECDDCD---------SCVMTLLNDLATMGEQLRLVKSQLQGLSA------- 1852
Query: 1179 CHQCFALWDVIIAELTNRTHRFLEKAKALK-----ISGVIGPYRETVDSVERKVSEI--- 1230
A L + +AK L+ I + ++ +ER+++++
Sbjct: 1853 -----------SAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQE 1901
Query: 1231 -----KDILAQSPAAEPL-KNIGNLFEEAEKLIKDVTEMMAQV----------EVKLSDT 1274
+ S A+ L N+ + A++L + ++ V + +
Sbjct: 1902 FETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGEN 1961
Query: 1275 TSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIK--NSDIRGALDSITKYFQMSLEAE 1332
+NS L+ + + L ++E A Q + N + AL +I Q ++
Sbjct: 1962 NGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAI----QRQVKEI 2017
Query: 1333 ERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSA 1392
+ + T+ +T + S L + +M + + ++++ EL+ K++ L SA
Sbjct: 2018 NSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSA 2077
Query: 1393 AAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVL 1452
+ S E + +E +R G A A+ +++L
Sbjct: 2078 GKTSLVEEAEKHARSLQELAK---QLEEIKRNASGDELVRCAVDAATAY-------ENIL 2127
Query: 1453 SALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATK--EKMDKSNEELRNLIKQIRNF 1510
+A+ K +A RA A +SA ++K + + + + ++++L N K +
Sbjct: 2128 NAI-------KAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKK 2180
Query: 1511 LTQD-SADLDSIEAVANEV-LKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADI 1568
L Q+ S L++++ N V ++ E+ T NLT +R+ + + + ++ A I
Sbjct: 2181 LKQEVSPALNNLQQTLNIVTVQKEVIDT-----NLT-TLRDGLHGIQRGDI-----DAMI 2229
Query: 1569 ARAEMLLEEAKRASKSATD----VKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQ 1624
+ A+ ++ +A + D ++ + +K+ + +KA+ AD +
Sbjct: 2230 SSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDF--KKALTDADNSVNKLT 2287
Query: 1625 NLLTSIESETAASEETLF---NASQRISELERNVEELKRKAAQ 1664
N L + + + + L N S + + +++ + A++
Sbjct: 2288 NKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASK 2330
Score = 110 bits (274), Expect = 2e-23
Identities = 159/792 (20%), Positives = 295/792 (37%), Gaps = 133/792 (16%)
Query: 988 EACDKETGRCL------KCLYHTEGEHCQFCRFGYYGDALQQDCRKCV-CNYLGTVQEHC 1040
EA D +GR C G+ CQ C GYY D +CV CN C
Sbjct: 1638 EASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCN--------C 1689
Query: 1041 NGSDCQCDKATGQCL-CLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSC--N 1097
NG QC +G C+ C N G++C+RC + A C C C +SF C N
Sbjct: 1690 NGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVN 1749
Query: 1098 EFTGQCQCMPGFGGRTCSECQELFWGDPDV---ECRACDCDPRGIETPQCDQSTGQCVCV 1154
+C C G+ G C C ++G+P C+ C C+ G + C TG C+
Sbjct: 1750 GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQ 1808
Query: 1155 EGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIG 1214
E + ++C DC C + L N E+ + +K
Sbjct: 1809 EPKDSSPAEEC--------DDCDSC----------VMTLLNDLATMGEQLRLVK------ 1844
Query: 1215 PYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDT 1274
S+++ + A + E ++++ E KD+ + +S+
Sbjct: 1845 -------------SQLQGLSASAGLLEQMRHM-------ETQAKDLRNQLLNYRSAISNH 1884
Query: 1275 TSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEER 1334
S+ +EL L E E+L + + + + + N ++ + Q + E + +
Sbjct: 1885 GSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNN--------NVNRATQSAKELDVK 1936
Query: 1335 VNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAA 1394
+ V ++ M +R+ + + L+E KL DL A
Sbjct: 1937 I--------KNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLS--DLRARL 1986
Query: 1395 EMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSA 1454
+ A+ + G N E ER G ++ L D
Sbjct: 1987 Q-------EAAAQAKQANGLN---QENERALG---------AIQRQVKEINSLQSDFTKY 2027
Query: 1455 LAEVEQLSKMVSEAKLRADEAKQSAEDILLKTN-ATKEKMDKSNEELRNLIKQIRNFLTQ 1513
L + + A +++++ E + N A +E DK E R+ K + + +
Sbjct: 2028 LTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGK--TSLVEE 2085
Query: 1514 DSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEM 1573
S++ +A ++ +++ ++ +L +R V++ + E IL I AE
Sbjct: 2086 AEKHARSLQELAKQLEEIKRNASGDEL------VRCAVDAATAYENILN----AIKAAED 2135
Query: 1574 LLEEAKRASKSATDVKVTADMVKEA----------LEEAEKAQVAAEKAIKQADEDIQGT 1623
A AS+SA + D+ ++A L EA+ Q ++ + A ++Q T
Sbjct: 2136 AANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQT 2195
Query: 1624 QNLLTSIESETAASEETLFNASQRI--SELERNVEELKRKAAQNSGEAEYIEKVVYTVKQ 1681
N++T + + TL + I +++ + K + + + + + ++
Sbjct: 2196 LNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQT 2255
Query: 1682 SAEDVKKTLDGELDEKYKK----VENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKL 1737
E +K T +E +KK +N + K T + D RK E + N+ L + +
Sbjct: 2256 DVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESI-NQQLLPLGNISDNM 2314
Query: 1738 QLLKDLERKYED 1749
+++L ++ D
Sbjct: 2315 DRIRELIQQARD 2326
Score = 103 bits (258), Expect = 1e-21
Identities = 58/191 (30%), Positives = 84/191 (43%), Gaps = 30/191 (15%)
Query: 359 GGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFS 418
GG C CQ N +GR C +C +Y P C+ C+C +C+ T
Sbjct: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFPR--------CKPCSC------GRRLCEEMT--- 1323
Query: 419 TGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP-CDSETG 477
GQCRC C+VC+ + S GC+ C C+ GTI P CD ++G
Sbjct: 1324 -----GQCRCPPRTVRPQCEVCET--HSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG 1376
Query: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
C CK +TG+ CD+C + C PC+C+ G C +G C C+ ++ G
Sbjct: 1377 QCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1432
Query: 538 RQCNEVEPGYY 548
+CN G +
Sbjct: 1433 TECNVCREGSF 1443
Score = 93.2 bits (230), Expect = 2e-18
Identities = 69/241 (28%), Positives = 99/241 (41%), Gaps = 45/241 (18%)
Query: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
V G C CR G C+ C+ +D P +C S +C D A
Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFP---------------HCQGSSSAC--DPA---G 590
Query: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGS-QNEGICD 412
T N + G C C+ + G C +CK Y+ D +P+ C C C AG+ G C
Sbjct: 591 TINSNLGYC-QCKLHVEGPTCSRCKLLYW---NLDKENPSGCSECKCHKAGTVSGTGECR 646
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPC 472
G C CK +V G+ CD C++G++ L + FGC+ C C+ G + + C
Sbjct: 647 QGD--------GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGAL--SSMC 696
Query: 473 DSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL--------DGCRPCDCDLGGALNNSCFA 524
+G C C+ V G+ C + PE+ DL DG P DL + F
Sbjct: 697 SGPSGVCQCREHVVGKVCQR--PENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFP 754
Query: 525 E 525
E
Sbjct: 755 E 755
Score = 92.8 bits (229), Expect = 3e-18
Identities = 69/229 (30%), Positives = 86/229 (37%), Gaps = 48/229 (20%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
G C C+ N G C C ++ P CK C+C +M
Sbjct: 1283 GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE---EMT------ 1323
Query: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQ-HPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
G C C T+ CE C+ + HP CE C C G+ + +
Sbjct: 1324 ----GQCR-CPPRTVRPQCEVCETHSFSFHPMAG------CEGCNCSRRGTIEAAMPECD 1372
Query: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
D +GQCRCK + G CD C GFY C C CN GT PG CD
Sbjct: 1373 RD------SGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNRDGTEPG--VCDP 1419
Query: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLS-NDLDGCRPCDCDLGGALNNSC 522
TG C CK V G C+ C + L +L GC C C +NN C
Sbjct: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC---FGVNNQC 1465
Score = 90.1 bits (222), Expect = 2e-17
Identities = 62/223 (27%), Positives = 83/223 (37%), Gaps = 65/223 (29%)
Query: 738 RCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPN 797
RCL R V+ P D CR+ +S AC C GS C GQC+CRP
Sbjct: 508 RCL--CRPGVEGPRCDTCRSGFYSFPICQ-----ACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 798 VVGRTCNRCAPGTFGF-------------------------------------------- 813
V G+ C+RC G + F
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
Query: 814 ---GPSGCKPCECHLQGSVNAF--CNPVTGQCHCFQGVYARQCDRCLPGHW-----GFPS 863
PSGC C+CH G+V+ C G CHC V CD C G++ +
Sbjct: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680
Query: 864 CQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCERCLAGYY 903
CQ CQC+ + C +G C C+++ +G C+R YY
Sbjct: 681 CQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722
Score = 89.4 bits (220), Expect = 3e-17
Identities = 57/211 (27%), Positives = 82/211 (38%), Gaps = 35/211 (16%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C C G +C+ C Y+ R +G + C CNCN HS C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
Query: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
G+C +CQHNT G +CE+C+ YY + C C C S F
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNS-----------F 1742
Query: 418 STGLIAG----QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
+TG + +C CK G C+ C G++ + C+ C+CN G + +P
Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 1802
Query: 474 SETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
+ + K + CD C L NDL
Sbjct: 1803 GDCINQEPKDSSPAEECDDCDSCVMTLLNDL 1833
Score = 88.6 bits (218), Expect = 5e-17
Identities = 51/143 (35%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Query: 769 TGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQ 826
TG C+ G S+ C G C C+ N G C RC G +G G C+ C C
Sbjct: 1681 TGRCVPCNCNGH-SNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHT 1739
Query: 827 GSVNAFC--NPVTGQCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQC--NGHADDCD 877
S C N +C C G QC+RC PG++G P SCQPC C NG C
Sbjct: 1740 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCH 1799
Query: 878 PVTGECLNCQ--DYTMGHNCERC 898
P+TG+C+N + D + C+ C
Sbjct: 1800 PLTGDCINQEPKDSSPAEECDDC 1822
Score = 81.3 bits (199), Expect = 8e-15
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 25/154 (16%)
Query: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
C C P G+ GQC C+ NV G C C G Y CK
Sbjct: 1266 CECHPTGATGPHCSPE---------GGQCPCQPNVIGRQCTRCATGHYGFPR-----CKP 1311
Query: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
C+C G C+ TG C C C+ C + + + GC C+C G
Sbjct: 1312 CSC-------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSF-HPMAGCEGCNCSRRGT 1363
Query: 518 LNNS---CFAESGQCSCRPHMIGRQCNEVEPGYY 548
+ + C +SGQC C+P + GRQC+ G+Y
Sbjct: 1364 IEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY 1397
Score = 79.3 bits (194), Expect = 3e-14
Identities = 50/171 (29%), Positives = 71/171 (41%), Gaps = 27/171 (15%)
Query: 365 CQHNTMGRNCEQCKPFYYQHPERDIRD--PNFCERCTCDPAGSQ---NEGICDSYTDFST 419
C G +C+ C P YY RD + C C C+ +Q GIC
Sbjct: 1656 CPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGIC-------- 1703
Query: 420 GLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC 479
C+ N GEHC+ C+EG+Y + C++C C + G + C
Sbjct: 1704 ------VNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRC 1755
Query: 480 YCKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQC 529
CK TG C++C P ++G G C+PC C+ G L SC +G C
Sbjct: 1756 SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDC 1805
Score = 78.6 bits (192), Expect = 5e-14
Identities = 59/199 (29%), Positives = 80/199 (40%), Gaps = 35/199 (17%)
Query: 792 CQCRPNVVGRTCNRCAPGTF----GFGPSGCKPCECHLQGSVNAFCNPVTGQC-HCFQGV 846
C C P G +C C+PG + G C PC C+ G N C +G C +C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNT 1710
Query: 847 YARQCDRCLPGHWG---FPSCQPCQC---NGHADDCDPVTGEC-LNCQDYTMGHNCERCL 899
C+RC G++G SC+ C C N A C G+ +C+ G CERC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 900 AGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCY--------QDPVTLQLACVCDPGYI 951
GY+G+P G C+PC C G SC+ Q+P A CD
Sbjct: 1771 PGYFGNP-QKFGGSCQPCSCNSNGQLG-----SCHPLTGDCINQEPKDSSPAEECDD--- 1821
Query: 952 GSRCDDCASGYFGNPSEVG 970
CD C + + +G
Sbjct: 1822 ---CDSCVMTLLNDLATMG 1837
Score = 75.1 bits (183), Expect = 6e-13
Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 46/146 (31%)
Query: 1080 GCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE----------- 1128
G PC C+ + GP C+ GQC C P GR C+ C +G P +
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEE 1321
Query: 1129 -------------------------------CRACDCDPRG-IET--PQCDQSTGQCVCV 1154
C C+C RG IE P+CD+ +GQC C
Sbjct: 1322 MTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCK 1381
Query: 1155 EGVEGPRCDKCTRGYSGVFPDCTPCH 1180
+ G +CD+C G+ FP+C PC+
Sbjct: 1382 PRITGRQCDRCASGFYR-FPECVPCN 1406
Score = 68.6 bits (166), Expect = 5e-11
Identities = 38/127 (29%), Positives = 53/127 (41%), Gaps = 10/127 (7%)
Query: 426 CRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKRL 484
C C G+ C C G+Y D G + C P N C +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHN 1709
Query: 485 VTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESG--QCSCRPHMIGRQCN 541
G+HC++C ++G N + G CR C C + C G +CSC+ G QC
Sbjct: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
Query: 542 EVEPGYY 548
PGY+
Sbjct: 1768 RCAPGYF 1774
Score = 67.4 bits (163), Expect = 1e-10
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 766 LHQTGLACECDPQGSLSSVCDPNGG--QCQCRPNVVGRTCNRCAPGTFG----FGPSGCK 819
+H + AC C S ++ C NGG +C C+ G C RCAPG FG FG S C+
Sbjct: 1727 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS-CQ 1785
Query: 820 PCECHLQGSVNAFCNPVTGQC---HCFQGVYARQCDRC 854
PC C+ G + + C+P+TG C A +CD C
Sbjct: 1786 PCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 60.5 bits (145), Expect = 1e-08
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
C C+ G+ VCDP G C C+ NV G CN C G+F P+ +L+G + F
Sbjct: 1405 CNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPA-------NLKGCTSCF 1457
Query: 833 CNPVTGQCH 841
C V QCH
Sbjct: 1458 CFGVNNQCH 1466
Score = 58.2 bits (139), Expect = 7e-08
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 49/191 (25%)
Query: 259 YYAVYDMVVRGNCF---CYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMD 314
YY + + G C C GH+++C DG G C+ C+HNT G +CE C +
Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQ--DG---------SGICVNCQHNTAGEHCERCQE 1720
Query: 315 FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV--SGGVCDDCQHNTMGR 372
Y+ +C+ C C H+ S ATG V G V C+ G
Sbjct: 1721 GYYG-------NAVHGSCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 1764
Query: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC---RCK 429
CE+C P Y+ +P+ + C+ C+C+ G G C T G C K
Sbjct: 1765 QCERCAPGYFGNPQ---KFGGSCQPCSCNSNGQL--GSCHPLT--------GDCINQEPK 1811
Query: 430 LNVEGEHCDVC 440
+ E CD C
Sbjct: 1812 DSSPAEECDDC 1822
Score = 51.2 bits (121), Expect = 9e-06
Identities = 20/43 (46%), Positives = 25/43 (58%)
Query: 506 GCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
G PC+C GA C E GQC C+P++IGRQC G+Y
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY 1304
Score = 37.0 bits (84), Expect = 0.17
Identities = 50/258 (19%), Positives = 97/258 (37%), Gaps = 34/258 (13%)
Query: 1540 LQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEAL 1599
+ L D+ E L V+ LQ +A LLE+ + A D++ + A+
Sbjct: 1826 VMTLLNDLATMGEQLRLVKSQLQGLSASAG----LLEQMRHMETQAKDLRNQLLNYRSAI 1881
Query: 1600 EEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELE------- 1652
E+ + +++ + Q + + A+Q EL+
Sbjct: 1882 SNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVI 1941
Query: 1653 RNVEELKR-------KAAQNSGEAEYIEKVVYTVKQSAEDVKKTLD---------GELDE 1696
RNV L R +N+G A I + + D++ L L++
Sbjct: 1942 RNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQ 2001
Query: 1697 KYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYE-------D 1749
+ ++ I ++ +E + A + L Q N LQL++ +++YE +
Sbjct: 2002 ENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNE 2061
Query: 1750 NQRYLEDKAQELARLEGE 1767
++ L DK +EL+R G+
Sbjct: 2062 ARQELSDKVRELSRSAGK 2079
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 9/71 (12%)
Query: 279 ECAPV----DGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK 334
EC P DG V G C+C+ N +G C +C + L + N C
Sbjct: 1401 ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL-----DPANLKGCTS 1455
Query: 335 CNCNEHSISCH 345
C C + CH
Sbjct: 1456 CFCFGVNNQCH 1466
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 254 bits (650), Expect = 4e-67
Identities = 144/418 (34%), Positives = 220/418 (52%), Gaps = 35/418 (8%)
Query: 35 CYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDK--KCFICNSQDPYHETLNPD 92
C P + G+ + V+STCG P YC+VS E++ C +CN+ DP + +P
Sbjct: 51 CIPDFVNAAFGK--DVRVSSTCG-RPPARYCVVSERGEERLRSCHLCNASDP--KKAHPP 105
Query: 93 SHLIENVVTTFAPNRLKIWWQSENGVE---NVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
+ L + P+ L W QSEN ++ NVT+ L L +F T++ + F + RP +M
Sbjct: 106 AFLTD----LNNPHNLTCW-QSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMA 160
Query: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDD--IICDSRYSDIEPSTEGEVIF 207
I +S D+G+TW +++++ C + P+ K ++ +C ++D+ P + G + F
Sbjct: 161 IYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAF 220
Query: 208 RALDPAFKIED-PYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMV 266
LD D SP +Q+ + T++R+ F +LHT GD D R+ Y+YAV D+
Sbjct: 221 STLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQ 280
Query: 267 VRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEG 326
V G C C GHA+ C + + +V C CRHNT G C+ C F++D PW+ A
Sbjct: 281 VGGRCKCNGHAARCV-----RDRDDSLV---CDCRHNTAGPECDRCKPFHYDRPWQRATA 332
Query: 327 RNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE 386
R +N C CNCN H+ C F+M +Y +G SGGVC +C+HNT GR+C CK YY+
Sbjct: 333 REANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMG 392
Query: 387 RDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
+ I C+ C C P G+ + C+ T GQC CK V G C+ C +G+
Sbjct: 393 KPITHRKACKACDCHPVGAAGK-TCNQTT--------GQCPCKDGVTGITCNRCAKGY 441
Score = 94.4 bits (233), Expect = 9e-19
Identities = 60/201 (29%), Positives = 81/201 (40%), Gaps = 32/201 (15%)
Query: 1011 FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCL----------CLPNV 1060
F R +GD + D +Y V + G C+C+ +C+ C N
Sbjct: 251 FSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNT 310
Query: 1061 IGQNCDRCAP----NTWQLASG---TGCDPCNCNA--------AHSFGPSCNEFTGQC-Q 1104
G CDRC P WQ A+ C CNCN + S + G C
Sbjct: 311 AGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLN 370
Query: 1105 CMPGFGGRTCSECQELFWGDPDVE------CRACDCDPRGIETPQCDQSTGQCVCVEGVE 1158
C GR C C+E ++ D C+ACDC P G C+Q+TGQC C +GV
Sbjct: 371 CRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVT 430
Query: 1159 GPRCDKCTRGYSGVFPDCTPC 1179
G C++C +GY PC
Sbjct: 431 GITCNRCAKGYQQSRSPIAPC 451
Score = 74.3 bits (181), Expect = 1e-12
Identities = 46/152 (30%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 942 LACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQC--HNNIDTTDPEACD--- 991
L C C G CD C ++ P + C C C H + E
Sbjct: 302 LVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG 361
Query: 992 -KETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQDCRKCVCNYLGTVQEHCNGSDC 1045
K G CL C ++T G HC +C+ GYY D ++ C+ C C+ +G + CN
Sbjct: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCN---- 417
Query: 1046 QCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077
+ TGQC C V G C+RCA Q S
Sbjct: 418 ---QTTGQCPCKDGVTGITCNRCAKGYQQSRS 446
Score = 70.5 bits (171), Expect = 1e-11
Identities = 50/180 (27%), Positives = 68/180 (37%), Gaps = 38/180 (21%)
Query: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDCD-----------P 878
C C +CDRC P H+ P C C CN HA C
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 879 VTGECLNCQDYTMGHNCERCLAGYYGD--PIIGSGDHCRPCPCPDGPDSGRQFARSCYQD 936
G CLNC+ T G +C C GYY D I C+ C C +G+ ++ Q
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ- 422
Query: 937 PVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ-----PCQCHNNIDTTDPEACD 991
C C G G C+ CA GY + S + + P ++++ +PE CD
Sbjct: 423 -------CPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVE--EPEDCD 473
Score = 62.4 bits (150), Expect = 4e-09
Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 788 NGGQC-QCRPNVVGRTCNRCAPGTF-GFGP-----SGCKPCECHLQGSVNAFCNPVTGQC 840
+GG C CR N GR C+ C G + G CK C+CH G+ CN TGQC
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
Query: 841 HCFQGVYARQCDRCLPGH 858
C GV C+RC G+
Sbjct: 424 PCKDGVTGITCNRCAKGY 441
Score = 60.8 bits (146), Expect = 1e-08
Identities = 40/147 (27%), Positives = 54/147 (36%), Gaps = 34/147 (23%)
Query: 426 CRCKLNVEGEHCDVCKEGFYD-----LSSEDPFGCKSCACN-------------PLGTIP 467
C C+ N G CD CK YD ++ + C +C CN L
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 468 GGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLD-------GCRPCDCDLGGALNN 520
G C + C+ G+HC C G D+ C+ CDC GA
Sbjct: 364 SGGVCLN------CRHNTAGRHCHYCKE---GYYRDMGKPITHRKACKACDCHPVGAAGK 414
Query: 521 SCFAESGQCSCRPHMIGRQCNEVEPGY 547
+C +GQC C+ + G CN GY
Sbjct: 415 TCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 50.8 bits (120), Expect = 1e-05
Identities = 19/38 (50%), Positives = 23/38 (60%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPG 809
AC+C P G+ C+ GQC C+ V G TCNRCA G
Sbjct: 403 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 15/85 (17%)
Query: 479 CYCKRLVTGQHCDQCLPEHW------GLSNDLDGCRPCDCDLGGA---LNNSCFAESGQC 529
C C+ G CD+C P H+ + + + C C+C+L N + SG+
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 530 S------CRPHMIGRQCNEVEPGYY 548
S CR + GR C+ + GYY
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYY 388
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 199 bits (506), Expect = 2e-50
Identities = 109/297 (36%), Positives = 154/297 (51%), Gaps = 21/297 (7%)
Query: 736 RYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLS-SVCDPNGGQCQC 794
+Y C N +S P+T N+ S + +T C C GSL+ + C+ GQC+C
Sbjct: 208 KYACESNLKSKY-LPLTQPVMNLRVSEAV---KTEYVCNCSVVGSLNVNRCNQTTGQCEC 263
Query: 795 RPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDR 853
RP G C C G + SG C+PC+C G+++ CN +G+C C GV CDR
Sbjct: 264 RPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDR 322
Query: 854 CLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSG 911
C G++GF C PCQCN + CD +TG CLNCQ+ + G++CE C G+Y P +
Sbjct: 323 CQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSP--DAT 380
Query: 912 DHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG 971
C CPC +G +S +P Q C GYIG C+ C +GY+ S
Sbjct: 381 KECLRCPCSAVTSTGSCSIKSSELEPECDQ----CKDGYIGPNCNKCENGYYNFDS---- 432
Query: 972 SCQPCQCHNNID-TTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRK 1027
C+ CQCH ++D P+ C E+G C+ CL++T G C+ C GY D L+ +C K
Sbjct: 433 ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-LEGNCIK 488
Score = 116 bits (290), Expect = 2e-25
Identities = 75/237 (31%), Positives = 105/237 (44%), Gaps = 29/237 (12%)
Query: 976 CQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGT 1035
C C + + + + C++ TG+C +C +G HC+ C+ G+Y + C+ C C+ G
Sbjct: 241 CNC-SVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGA 298
Query: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPS 1095
+ CN S G+C C VIG CDRC + S GC PC CN + S
Sbjct: 299 LSIPCNSS--------GKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCN---NRSAS 346
Query: 1096 CNEFTGQC-QCMPGFGGRTCSECQELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCV 1152
C+ TG C C G C EC+E F+ PD EC C C STG C
Sbjct: 347 CDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC--------SAVTSTGSCS 398
Query: 1153 CVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKI 1209
P CD+C GY G P+C C + +D I + + H ++ K KI
Sbjct: 399 IKSSELEPECDQCKDGYIG--PNCNKCENGYYNFDSICRKC--QCHGHVDPVKTPKI 451
Score = 98.6 bits (244), Expect = 5e-20
Identities = 57/152 (37%), Positives = 78/152 (51%), Gaps = 19/152 (12%)
Query: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
C C GS N C+ T GQC C+ +G HC+ CKEGFY L+ C+
Sbjct: 241 CNCSVVGSLNVNRCNQTT--------GQCECRPGYQGLHCETCKEGFY-LNYTSGL-CQP 290
Query: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
C C+P G + PC+S +G C CK V G CD+C ++G S +GC PC C+ A
Sbjct: 291 CDCSPHGAL--SIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSK--NGCLPCQCNNRSA 345
Query: 518 LNNSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
SC A +G C +C+ + G C E + G+Y
Sbjct: 346 ---SCDALTGACLNCQENSKGNHCEECKEGFY 374
Score = 97.4 bits (241), Expect = 1e-19
Identities = 69/251 (27%), Positives = 101/251 (40%), Gaps = 48/251 (19%)
Query: 259 YYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHD 318
+Y Y + C C H + P + G C C+ G C+ C D Y+
Sbjct: 279 FYLNYTSGLCQPCDCSPHGALSIPCNS---------SGKCQCKVGVIGSICDRCQDGYY- 328
Query: 319 LPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCK 378
G + N C C CN S SC + G C +CQ N+ G +CE+CK
Sbjct: 329 -------GFSKNGCLPCQCNNRSASC-----------DALTGACLNCQENSKGNHCEECK 370
Query: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHC 437
+YQ P+ C RC C S G C + + +C +CK G +C
Sbjct: 371 EGFYQSPDA----TKECLRCPCSAVTS--TGSC----SIKSSELEPECDQCKDGYIGPNC 420
Query: 438 DVCKEGFYDLSSEDPFGCKSCACN-PLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLP 495
+ C+ G+Y+ S C+ C C+ + + C E+G C C TG C+ CL
Sbjct: 421 NKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLE 476
Query: 496 EHWGLSNDLDG 506
G +DL+G
Sbjct: 477 ---GYVHDLEG 484
Score = 93.2 bits (230), Expect = 2e-18
Identities = 83/346 (23%), Positives = 129/346 (37%), Gaps = 67/346 (19%)
Query: 217 EDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGH 276
E P SP + + + K++ + NL + + + V+ C
Sbjct: 185 EAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVC--- 241
Query: 277 ASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCN 336
C+ V N G C CR +GL+CE C + ++ S C+ C+
Sbjct: 242 --NCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-------LNYTSGLCQPCD 292
Query: 337 CNEH---SISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPN 393
C+ H SI C+ S G C C+ +G C++C+ YY + N
Sbjct: 293 CSPHGALSIPCN------------SSGKC-QCKVGVIGSICDRCQDGYYGFSK------N 333
Query: 394 FCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSSEDP 452
C C C + CD+ T G C C+ N +G HC+ CKEGFY + P
Sbjct: 334 GCLPCQC----NNRSASCDALT--------GACLNCQENSKGNHCEECKEGFY----QSP 377
Query: 453 FGCKSCACNPLGTIPGGNPCDSETGHC-----YCKRLVTGQHCDQCLPEHWGLSNDLDGC 507
K C P + C ++ CK G +C++C ++ + C
Sbjct: 378 DATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI---C 434
Query: 508 RPCDCDLGGALN-----NSCFAESGQC-SCRPHMIGRQCNEVEPGY 547
R C C G ++ C ESG+C +C + G C GY
Sbjct: 435 RKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
Score = 91.7 bits (226), Expect = 6e-18
Identities = 61/216 (28%), Positives = 95/216 (43%), Gaps = 31/216 (14%)
Query: 339 EHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERC 398
E+ +C ++ + N + G C+ C+ G +CE CK +Y + + C+ C
Sbjct: 238 EYVCNCSVVGSLNVNRCNQTTGQCE-CRPGYQGLHCETCKEGFYLNYTSGL-----CQPC 291
Query: 399 TCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSC 458
C P G+ + C+S +G+C+CK+ V G CD C++G+Y S GC C
Sbjct: 292 DCSPHGALSIP-CNS---------SGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPC 338
Query: 459 ACNPLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
CN CD+ TG C C+ G HC++C + + C C C +
Sbjct: 339 QCNNRSA-----SCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTS 393
Query: 518 LNNSCFAESGQCS-----CRPHMIGRQCNEVEPGYY 548
SC +S + C+ IG CN+ E GYY
Sbjct: 394 -TGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYY 428
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 198 bits (503), Expect = 4e-50
Identities = 144/491 (29%), Positives = 215/491 (43%), Gaps = 61/491 (12%)
Query: 2 GLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKP 61
GLL F AL +P G A C P + +GR ++ +STCG +P
Sbjct: 7 GLLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGR--EVLASSTCG--RP 62
Query: 62 EPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSEN---GV 118
C++ DP L+ + T +P + W+SE+
Sbjct: 63 ATRA-------------CDASDPRRAH---SPALLTSPGGTASP----LCWRSESLPRAP 102
Query: 119 ENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASF---P 175
NVT+ + L F + + F + PA++ + +S D G++W +F+ C+ + P
Sbjct: 103 LNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162
Query: 176 GISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALD---PAFKIEDPYSPRIQNLLKITN 232
+ GP + +C +P G + F D P ++ SP +Q+ + T+
Sbjct: 163 APANGPAGPGPEALCFPAPL-AQPDGSGLLAFSMQDSSPPGLDLDS--SPVLQDWVTATD 219
Query: 233 LRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEG 292
+R+ + T GD ME Y YA D+ V G C C GHAS C ++
Sbjct: 220 VRVVLTRPSTAGD---PRDMEAVVPYSYAATDLQVGGRCKCNGHASRCL--------LDT 268
Query: 293 MVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYL 352
H C CRH T+G +C C FY D PW+ A R S+AC C+CN H+ C F+M +Y
Sbjct: 269 QGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYR 328
Query: 353 ATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICD 412
+G SGGVC +C+HNT GR+C C+ +Y+ P R + D C C C P G+ + C+
Sbjct: 329 LSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGK-TCN 387
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPL-GTIPGGNP 471
T GQC CK V G C+ C GF S P C P+ G +P
Sbjct: 388 QTT--------GQCPCKDGVTGLTCNRCAPGFQ--QSRSPVA--PCVKTPIPGPTEDSSP 435
Query: 472 CDSETGHCYCK 482
+ +CK
Sbjct: 436 VQPQDCDSHCK 446
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/170 (31%), Positives = 68/170 (40%), Gaps = 32/170 (18%)
Query: 1042 GSDCQCDKATGQCL----------CLPNVIGQNCDRCAP----NTWQLASGT---GCDPC 1084
G C+C+ +CL C G +C RC P WQ A+ C C
Sbjct: 252 GGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311
Query: 1085 NCNA--------AHSFGPSCNEFTGQC-QCMPGFGGRTCSECQELFWGDPDVE------C 1129
+CN + S G C C GR C C+E F+ DP C
Sbjct: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371
Query: 1130 RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPC 1179
RACDC P G C+Q+TGQC C +GV G C++C G+ PC
Sbjct: 372 RACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421
Score = 75.5 bits (184), Expect = 4e-13
Identities = 48/159 (30%), Positives = 66/159 (41%), Gaps = 25/159 (15%)
Query: 942 LACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQCHNNIDTTDPE------AC 990
L C C G G C C Y P + +C C C+ + +
Sbjct: 272 LICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSG 331
Query: 991 DKETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQDCRKCVCNYLGTVQEHCNGSDC 1045
+ G CL C ++T G HC +CR G+Y D + ++ CR C C+ +G + CN
Sbjct: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCN---- 387
Query: 1046 QCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPC 1084
+ TGQC C V G C+RCAP Q S PC
Sbjct: 388 ---QTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVA--PC 421
Score = 71.6 bits (174), Expect = 6e-12
Identities = 59/217 (27%), Positives = 78/217 (35%), Gaps = 57/217 (26%)
Query: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDCD-----------P 878
C C G C RC P + P +C C CNGHA C
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 879 VTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDH--CRPCPCPDGPDSGRQFARSCYQD 936
G CLNC+ T G +C C G+Y DP D CR C C +G+ ++ Q
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ- 392
Query: 937 PVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC------QCHNNIDTTDPEAC 990
C C G G C+ CA G+ + S V PC + P+ C
Sbjct: 393 -------CPCKDGVTGLTCNRCAPGFQQSRSPVA----PCVKTPIPGPTEDSSPVQPQDC 441
Query: 991 DKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRK 1027
D HC+ R G Y +L++ C+K
Sbjct: 442 D---------------SHCKPAR-GSYRISLKKFCKK 462
Score = 65.5 bits (158), Expect = 5e-10
Identities = 37/103 (35%), Positives = 44/103 (42%), Gaps = 11/103 (10%)
Query: 788 NGGQC-QCRPNVVGRTCNRCA------PGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC 840
+GG C CR N GR C+ C PG C+ C+CH G+ CN TGQC
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393
Query: 841 HCFQGVYARQCDRCLPGHWGFPS----CQPCQCNGHADDCDPV 879
C GV C+RC PG S C G +D PV
Sbjct: 394 PCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPV 436
Score = 63.5 bits (153), Expect = 2e-09
Identities = 45/156 (28%), Positives = 63/156 (40%), Gaps = 34/156 (21%)
Query: 992 KETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYL------GTVQE------- 1038
K G +CL T+G CR G G DC +C Y T +E
Sbjct: 256 KCNGHASRCLLDTQGHLICDCRHGTEG----PDCGRCKPFYCDRPWQRATARESHACLAC 311
Query: 1039 HCNGSDCQC-----------DKATGQCL-CLPNVIGQNCDRCAPNTWQ-----LASGTGC 1081
CNG +C ++ G CL C N G++C C ++ L+ C
Sbjct: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371
Query: 1082 DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSEC 1117
C+C+ + G +CN+ TGQC C G G TC+ C
Sbjct: 372 RACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407
Score = 62.8 bits (151), Expect = 3e-09
Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 24/142 (16%)
Query: 426 CRCKLNVEGEHCDVCKEGFYD-----LSSEDPFGCKSCACN----------PLGTIPGGN 470
C C+ EG C CK + D ++ + C +C+CN L + G
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 471 PCDSETGHCY-CKRLVTGQHCDQCLPEHWG----LSNDLDGCRPCDCDLGGALNNSCFAE 525
G C C+ G+HC C + +D CR CDC GA +C
Sbjct: 334 ----SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQT 389
Query: 526 SGQCSCRPHMIGRQCNEVEPGY 547
+GQC C+ + G CN PG+
Sbjct: 390 TGQCPCKDGVTGLTCNRCAPGF 411
Score = 56.2 bits (134), Expect = 3e-07
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 12/91 (13%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831
AC+C P G+ C+ GQC C+ V G TCNRCAPG F S PC
Sbjct: 373 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG-FQQSRSPVAPC---------- 421
Query: 832 FCNPVTGQCHCFQGVYARQCD-RCLPGHWGF 861
P+ G V + CD C P +
Sbjct: 422 VKTPIPGPTEDSSPVQPQDCDSHCKPARGSY 452
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 172 bits (436), Expect = 3e-42
Identities = 141/424 (33%), Positives = 172/424 (40%), Gaps = 84/424 (19%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSV 829
L C C G+ C G+C C P G C + C PGTFG S + C CH G
Sbjct: 230 LRCPCQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCS--QDCPCHHGGQ- 282
Query: 830 NAFCNPVTGQCHCFQGVYARQC-DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQD 888
C+ VTGQCHC G +C + C G +GF Q C C+ + C P TG C C+
Sbjct: 283 ---CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCH-NGGQCSPTTGAC-ECEP 337
Query: 889 YTMGHNCER--CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
G C+ C G +G PCPC D+ SC+ PVT AC C
Sbjct: 338 GYKGPRCQERLCPEGLHGPGCT------LPCPC----DADNTI--SCH--PVTG--ACTC 381
Query: 947 DPGYIGSRCDD-CASGYFGNPSEVGGSCQ-PCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
PG+ G C++ C GY+G+ CQ PC C N D C TG C C
Sbjct: 382 QPGWSGHHCNESCPVGYYGD------GCQLPCTCQNGAD------CHSITGGCT-CAPGF 428
Query: 1005 EGEHCQF-CRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
GE C C G YG +C C CN GT C G C C G
Sbjct: 429 MGEVCAVSCAAGTYGP----NCSSICSCNNGGT-----------CSPVDGSCTCKEGWQG 473
Query: 1063 QNCDR-CAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQEL 1120
+C C TW L C N G +C+ G C C PG+ G TC C +
Sbjct: 474 LDCTLPCPSGTWGLNCNESCTCAN-------GAACSPIDGSCSCTPGWLGDTCELPCPDG 526
Query: 1121 FWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-CTRGYSGVFPDCTP 1178
+G + C CDC CD TG C C+ G G RCD C G G P+C+
Sbjct: 527 TFG---LNCSEHCDCS----HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG--PNCSV 577
Query: 1179 CHQC 1182
C
Sbjct: 578 SCSC 581
Score = 171 bits (434), Expect = 4e-42
Identities = 151/482 (31%), Positives = 187/482 (38%), Gaps = 121/482 (25%)
Query: 766 LHQTG--LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCK-PCE 822
LH G L C CD ++S C P G C C+P G CN P G+ GC+ PC
Sbjct: 353 LHGPGCTLPCPCDADNTIS--CHPVTGACTCQPGWSGHHCNESCP--VGYYGDGCQLPCT 408
Query: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCD-RCLPGHWGFPSCQP-CQCNGHADDCDPVT 880
C A C+ +TG C C G C C G +G P+C C CN + C PV
Sbjct: 409 C----QNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCN-NGGTCSPVD 462
Query: 881 GEC------------LNCQDYTMGHNCER---CLAGYYGDPIIGS--------GDHCRPC 917
G C L C T G NC C G PI GS GD C
Sbjct: 463 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE-L 521
Query: 918 PCPDGPDSGRQFARSCYQ----------DPVTLQLACVCDPGYIGSRCDD-CASGYFGNP 966
PCPDG F +C + DPVT C C G+ G RCD C G +G
Sbjct: 522 PCPDG-----TFGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCDSTCPPGRWGPN 574
Query: 967 SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQ-FCRFGYYGDALQQDC 1025
V C C N +C E G C +C G CQ C G+YG Q C
Sbjct: 575 CSVS-----CSCENG------GSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCAQPC 622
Query: 1026 RKCV-----CNYLGTVQE--------HCN--------GSDC----------QCDKATGQC 1054
CV C+++ + E CN G DC C G C
Sbjct: 623 PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSC 682
Query: 1055 LCLPNVIGQNCDR-CAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
C P IG++C + C P W G C C+C+ G SC+ G C C PG+ G
Sbjct: 683 QCFPGWIGKDCSQACPPGFW----GPACFHACSCHN----GASCSAEDGACHCTPGWTGL 734
Query: 1113 TCSE-CQELFWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGY 1169
C++ C F+G +C R C C CD +G+C C G G C+ +C G
Sbjct: 735 FCTQRCPAAFFGK---DCGRVCQCQ----NGASCDHISGKCTCRTGFTGQHCEQRCAPGT 787
Query: 1170 SG 1171
G
Sbjct: 788 FG 789
Score = 151 bits (382), Expect = 5e-36
Identities = 126/421 (29%), Positives = 156/421 (37%), Gaps = 91/421 (21%)
Query: 792 CQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQC 851
C C P G C+ +GP C+C A CNP+TG C C G +C
Sbjct: 118 CHCEPGWGGPDCSSGCDSDH-WGPHCSNRCQCQN----GALCNPITGACVCAAGFRGWRC 172
Query: 852 DR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGS 910
+ C PG G PCQC H CDP GECL YT + E C G +G
Sbjct: 173 EELCAPGTHGKGCQLPCQCR-HGASCDPRAGECLCAPGYTGVYCEELCPPGSHGA----- 226
Query: 911 GDHCR-PCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRC-DDCASGYFGNPSE 968
HC CPC +G +C+ + C C PG+ G+ C C G FG
Sbjct: 227 --HCELRCPCQNGG--------TCHH----ITGECACPPGWTGAVCAQPCPPGTFGQ--- 269
Query: 969 VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQDCR- 1026
Q C CH+ CD TG+C C G+ CQ C FG +G Q C
Sbjct: 270 --NCSQDCPCHHG------GQCDHVTGQC-HCTAGYMGDRCQEECPFGSFGFQCSQHCDC 320
Query: 1027 -------------KCVCNYLGT------VQEHCNGSDC------------QCDKATGQCL 1055
+C Y G E +G C C TG C
Sbjct: 321 HNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACT 380
Query: 1056 CLPNVIGQNCDRCAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTC 1114
C P G +C+ P + G GC PC C G C+ TG C C PGF G C
Sbjct: 381 CQPGWSGHHCNESCPVGYY---GDGCQLPCTCQN----GADCHSITGGCTCAPGFMGEVC 433
Query: 1115 S-ECQELFWGDPDVECRA-CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSG 1171
+ C +G C + C C+ G C G C C EG +G C C G G
Sbjct: 434 AVSCAAGTYGP---NCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWG 486
Query: 1172 V 1172
+
Sbjct: 487 L 487
Score = 127 bits (319), Expect = 1e-28
Identities = 118/399 (29%), Positives = 144/399 (36%), Gaps = 109/399 (27%)
Query: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCEC-HLQG 827
GL C + + C P G C C P +G TC C GTFG S + C+C H G
Sbjct: 486 GLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS--EHCDCSHADG 543
Query: 828 SVNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQ-PCQCNGHADDCDPVTGECLN 885
C+PVTG C C G +CD C PG WG P+C C C + C P G C
Sbjct: 544 -----CDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCE-NGGSCSPEDGSC-E 595
Query: 886 CQDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
C G C+R C G+YG H PCP S +R C+ + C
Sbjct: 596 CAPGFRGPLCQRICPPGFYG--------HGCAQPCPLCVHS----SRPCHH----ISGIC 639
Query: 945 VCDPGYIGSRCDD-CASGYFGNP-------------SEVGGSCQ---------------- 974
C PG+ G+ C+ CA GYFG S + GSCQ
Sbjct: 640 ECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPP 699
Query: 975 ---------PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC-QFCRFGYYGDALQQD 1024
C CHN +C E G C C G C Q C ++G +
Sbjct: 700 GFWGPACFHACSCHNGA------SCSAEDGAC-HCTPGWTGLFCTQRCPAAFFGKDCGRV 752
Query: 1025 CR------------KCVCNYLGTVQEHCN--------GSDCQ----------CDKATGQC 1054
C+ KC C G +HC G CQ CD TG C
Sbjct: 753 CQCQNGASCDHISGKCTCR-TGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTC 811
Query: 1055 LCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFG 1093
C P G CD+ A +L T P HS G
Sbjct: 812 YCSPGFKGIRCDQAALMMEELNPYTKISPALGAERHSVG 850
Score = 79.3 bits (194), Expect = 3e-14
Identities = 72/258 (27%), Positives = 90/258 (34%), Gaps = 65/258 (25%)
Query: 296 GHCMCRHNTKGLNCE-LCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
G C+C G+ CE LC P ++ +C C ++ +CH
Sbjct: 202 GECLCAPGYTGVYCEELC----------PPGSHGAHCELRCPC-QNGGTCHHITGECACP 250
Query: 355 GNVSGGVC-DDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
+G VC C T G+NC Q C C G CD
Sbjct: 251 PGWTGAVCAQPCPPGTFGQNCSQ--------------------DCPCHHGGQ-----CDH 285
Query: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
T GQC C G+ C E PFG C+ G C
Sbjct: 286 VT--------GQCHCTAGYMGDRCQ----------EECPFGSFGFQCSQHCDCHNGGQCS 327
Query: 474 SETGHCYCKRLVTGQHCDQCL-PEHWGLSNDLDGCR-PCDCDLGGALNNSCFAESGQCSC 531
TG C C+ G C + L PE GL GC PC CD + SC +G C+C
Sbjct: 328 PTTGACECEPGYKGPRCQERLCPE--GLHGP--GCTLPCPCDADNTI--SCHPVTGACTC 381
Query: 532 RPHMIGRQCNEVEP-GYY 548
+P G CNE P GYY
Sbjct: 382 QPGWSGHHCNESCPVGYY 399
Score = 70.9 bits (172), Expect = 1e-11
Identities = 86/335 (25%), Positives = 112/335 (33%), Gaps = 71/335 (21%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM--CRHNTKGLNCELCMDFYHDLPWRPAEGRN 328
C C + C+PVDG EG C C T GLNC + P +G
Sbjct: 450 CSC-NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSC 508
Query: 329 S-------NACKK--------CNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRN 373
S + C+ NC+EH H D V+G C C G
Sbjct: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD-----GCDPVTGHCC--CLAGWTGIR 561
Query: 374 CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVE 433
C+ P P R PN C+C+ GS C G C C
Sbjct: 562 CDSTCP-----PGR--WGPNCSVSCSCENGGS-----CSPED--------GSCECAPGFR 601
Query: 434 GEHCD-VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ 492
G C +C GFY P C C + PC +G C C +G C+Q
Sbjct: 602 GPLCQRICPPGFYGHGCAQP--CPLC-------VHSSRPCHHISGICECLPGFSGALCNQ 652
Query: 493 -CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEV-EPGYYFA 550
C ++G D + C C A N +C G C C P IG+ C++ PG++
Sbjct: 653 VCAGGYFGQ----DCAQLCSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGP 704
Query: 551 TLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTG 585
H + G S P WTG
Sbjct: 705 ACFH------ACSCHNGASCSAEDGACHCTPGWTG 733
Score = 65.5 bits (158), Expect = 5e-10
Identities = 80/280 (28%), Positives = 99/280 (35%), Gaps = 86/280 (30%)
Query: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE--LCMDFYHDLPWRPAEGR 327
+C C+ + +C+P G C C KG C+ LC EG
Sbjct: 317 HCDCH-NGGQCSPTTGA-----------CECEPGYKGPRCQERLC-----------PEGL 353
Query: 328 NSNACK-KCNCN-EHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNC-EQCKPFYYQH 384
+ C C C+ +++ISCH G C CQ G +C E C YY
Sbjct: 354 HGPGCTLPCPCDADNTISCH-----------PVTGACT-CQPGWSGHHCNESCPVGYYG- 400
Query: 385 PERDIRDPNFCER-CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDV-CKE 442
+ C+ CTC QN C S T G C C GE C V C
Sbjct: 401 --------DGCQLPCTC-----QNGADCHSIT--------GGCTCAPGFMGEVCAVSCAA 439
Query: 443 GFYDLSSEDPFGCKS-CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD-QCLPEHWGL 500
G Y + C S C+CN GT C G C CK G C C WGL
Sbjct: 440 GTYGPN------CSSICSCNNGGT------CSPVDGSCTCKEGWQGLDCTLPCPSGTWGL 487
Query: 501 SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
+ + C C G A C G CSC P +G C
Sbjct: 488 NCN----ESCTCANGAA----CSPIDGSCSCTPGWLGDTC 519
Score = 62.0 bits (149), Expect = 5e-09
Identities = 75/322 (23%), Positives = 101/322 (31%), Gaps = 81/322 (25%)
Query: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
+C C HA C PV G HC C G+ C+ P
Sbjct: 535 HCDC-SHADGCDPVTG-----------HCCCLAGWTGIRCDSTC---------PPGRWGP 573
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERD 388
N C+C E+ SC + G +C C G C Q P
Sbjct: 574 NCSVSCSC-ENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPC 632
Query: 389 IRDPNFCER------------CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEH 436
CE C G +C + + I G C+C G+
Sbjct: 633 HHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKD 692
Query: 437 CD-VCKEGFYDLSSEDPFGCKS----------CACNPLGT-------------------- 465
C C GF+ + C + C C P T
Sbjct: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV 752
Query: 466 --IPGGNPCDSETGHCYCKRLVTGQHCDQ-CLPEHWGLSNDLDGCRP-CDCDLGGALNNS 521
G CD +G C C+ TGQHC+Q C P +G GC+ C+C +NNS
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY-----GCQQLCEC-----MNNS 802
Query: 522 -CFAESGQCSCRPHMIGRQCNE 542
C +G C C P G +C++
Sbjct: 803 TCDHVTGTCYCSPGFKGIRCDQ 824
Score = 56.6 bits (135), Expect = 2e-07
Identities = 50/203 (24%), Positives = 66/203 (32%), Gaps = 45/203 (22%)
Query: 369 TMGRNCEQCKPFYYQ------------------------HPERDIRDPNFCERCTCDPAG 404
TM R QC P YY+ H E P+ C D G
Sbjct: 80 TMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWG 139
Query: 405 SQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD-VCKEGFYDLSSEDPFGCKSCACNPL 463
C I G C C G C+ +C G + + P C+
Sbjct: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRH------ 193
Query: 464 GTIPGGNPCDSETGHCYCKRLVTGQHCDQ-CLPEHWGLSNDLDGCRPCDCDLGGALNNSC 522
G CD G C C TG +C++ C P G +L C C GG +C
Sbjct: 194 -----GASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCEL----RCPCQNGG----TC 240
Query: 523 FAESGQCSCRPHMIGRQCNEVEP 545
+G+C+C P G C + P
Sbjct: 241 HHITGECACPPGWTGAVCAQPCP 263
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 171 bits (434), Expect = 4e-42
Identities = 100/280 (35%), Positives = 137/280 (48%), Gaps = 34/280 (12%)
Query: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860
C+R A G P + +V P T + G ++C G H
Sbjct: 21 CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75
Query: 861 FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
C PC CNG++++C +G C++CQ T G +CE+CL GY GD I G+ C+PCPCP
Sbjct: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
Query: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
FA SCY+ ++ C+C+ Y G C+ CA GY+GNP +G +C+ C C
Sbjct: 136 --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191
Query: 981 NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035
N +DP E CD+ TG+C CL +T G C+ C GYYGDA + ++C VCN
Sbjct: 192 N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242
Query: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
C G CD TG+CL CD+C W L
Sbjct: 243 ----CGGG--PCDSVTGECLEEGFEPPTGCDKC---VWDL 273
Score = 142 bits (359), Expect = 2e-33
Identities = 180/820 (21%), Positives = 328/820 (40%), Gaps = 120/820 (14%)
Query: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
G + + C +G+F S G C PC C+ N + C +G C+ C +T GEH
Sbjct: 58 GRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNE-----CLDGSGYCVHCQRNTTGEH 109
Query: 1009 CQFCRFGYYGDALQ---QDCRKCVCN--YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063
C+ C GY GD+++ Q C+ C C +L E C + +C+C N G
Sbjct: 110 CEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKN-----GAVRCICNENYAGP 164
Query: 1064 NCDRCAPNTW--QLASGTGCDPCNCNA---AHSFGPSCNEFTGQCQ-CMPGFGGRTCSEC 1117
NC+RCAP + L G+ C C+C+ + C+E TGQC+ C+ G C C
Sbjct: 165 NCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Query: 1118 QELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR-CDKCT-------- 1166
++GD + C C+C CD TG+C+ EG E P CDKC
Sbjct: 225 APGYYGDARIAKNCAVCNCGGG-----PCDSVTGECL-EEGFEPPTGCDKCVWDLTDALR 278
Query: 1167 -------RGYSGVFPDCTPC------HQCFALWDVIIAELTNRTHRFLEKAKALKISGVI 1213
G SGV + ++ A ++ +L+ R +++ + ++I+
Sbjct: 279 LAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA--LRKIQINNAE 336
Query: 1214 GPYRETVDSVERKVSEI-----KDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQV- 1267
+ + VE V + K L Q + + + + L E+A + + E+ ++
Sbjct: 337 NTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKML 396
Query: 1268 ---------EVKLSDTTSQSNSTAKELDSLQ---TEAESLDNTVKELAEQLEFIKNSDIR 1315
++S+ + +E+ S Q T+ E +D +E E E + ++
Sbjct: 397 YYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVD---EEADEAYELLSQAESW 453
Query: 1316 GALDSITK-YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQ 1374
L + T+ F + LE + NA ++ ++Q+ ED+ ++ ++ +++Q
Sbjct: 454 QRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQ 513
Query: 1375 ARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE-----CGGPNCRTDEGERKCGGPG 1429
R+ +++ ++ ++ LS +A+ T P + SE + G D G +
Sbjct: 514 ERVREQM--EVVNMSLSTSADSL--TTPRLTLSELDDIIKNASGIYAEID-GAKSELQVK 568
Query: 1430 CGGLVTVAHNAWQKAMDLDQDV-----------------------LSALAEVEQLSKMVS 1466
L ++H+ Q+A+D QD+ L A E + VS
Sbjct: 569 LSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628
Query: 1467 EAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVAN 1526
EA A+ A + + I + ++ +E NL+ Q R Q A+ S EAVA+
Sbjct: 629 EANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVAD 686
Query: 1527 EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSAT 1586
+ + L + + V+ L E + + ++ ++ EEA R +
Sbjct: 687 --TSRRVGGALARKSALKTRLSDAVKQLQAAE--RGDAQQRLGQSRLITEEANRTTMEVQ 742
Query: 1587 DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQ 1646
+ TA M ++ Q A A + LT + + T+ +
Sbjct: 743 --QATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTV-EQKR 799
Query: 1647 RISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686
S + +++ ++ AQ A I+ + QSA +V
Sbjct: 800 PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 839
Score = 113 bits (282), Expect = 2e-24
Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%)
Query: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824
+G CD G+ + D +G C+ N G C +C G G P C+PC C
Sbjct: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
Query: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874
L N C G +C C + C+RC PG++G P +C+ C C+G++D
Sbjct: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195
Query: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
DCD VTG+C NC T G CERC GYYGD I +C C C GP
Sbjct: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247
Score = 93.6 bits (231), Expect = 2e-18
Identities = 77/241 (31%), Positives = 110/241 (45%), Gaps = 52/241 (21%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
C C G+++EC +DG G+C+ C+ NT G +CE C+D Y R A
Sbjct: 82 CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
C+ C C ++ +F + Y +G V C N G NCE+C P YY +P +
Sbjct: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178
Query: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444
+ C++C C +G+ + + CD T GQCR C N G C+ C G+
Sbjct: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228
Query: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND 503
Y D K+CA CN GG PCDS TG C + CD+C+ W L++
Sbjct: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDA 276
Query: 504 L 504
L
Sbjct: 277 L 277
Score = 83.2 bits (204), Expect = 2e-15
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%)
Query: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
S C C+CN +S C D G C CQ NT G +CE+C Y R
Sbjct: 76 SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
P FC+ C C P + C A +C C N G +C+ C G+Y
Sbjct: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176
Query: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504
CK C C+ + P CD TG C C R TG C++C P ++G +
Sbjct: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 505 DGCRPCDCDLGGALNNSCFAESGQC 529
C C+C GG C + +G+C
Sbjct: 236 KNCAVCNC--GG---GPCDSVTGEC 255
Score = 82.8 bits (203), Expect = 3e-15
Identities = 44/120 (36%), Positives = 60/120 (50%), Gaps = 14/120 (11%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843
+C C N G C RCAPG +G S CK C+C N C+ VTGQC +C
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213
Query: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCL 899
+ +C+RC PG++G +C C C G CD VTGECL + + C++C+
Sbjct: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECLE-EGFEPPTGCDKCV 270
Score = 68.6 bits (166), Expect = 5e-11
Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%)
Query: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457
CD G+ NE + S G C C+ N GEHC+ C +G+ D P C+
Sbjct: 82 CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131
Query: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511
C C PL + C + G C C G +C++C P ++G N L C+ CD
Sbjct: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188
Query: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
C N C +GQC +C + G +C PGYY
Sbjct: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 67.0 bits (162), Expect = 2e-10
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498
C GF+ S + C C CN N C +G+C +C+R TG+HC++CL +
Sbjct: 67 CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
Query: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548
G + C+PC C L N SC+ ++G +C C + G C PGYY
Sbjct: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 171 bits (434), Expect = 4e-42
Identities = 100/280 (35%), Positives = 137/280 (48%), Gaps = 34/280 (12%)
Query: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860
C+R A G P + +V P T + G ++C G H
Sbjct: 21 CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75
Query: 861 FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
C PC CNG++++C +G C++CQ T G +CE+CL GY GD I G+ C+PCPCP
Sbjct: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
Query: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
FA SCY+ ++ C+C+ Y G C+ CA GY+GNP +G +C+ C C
Sbjct: 136 --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191
Query: 981 NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035
N +DP E CD+ TG+C CL +T G C+ C GYYGDA + ++C VCN
Sbjct: 192 N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242
Query: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
C G CD TG+CL CD+C W L
Sbjct: 243 ----CGGG--PCDSVTGECLEEGFEPPTGCDKC---VWDL 273
Score = 142 bits (359), Expect = 2e-33
Identities = 180/820 (21%), Positives = 328/820 (40%), Gaps = 120/820 (14%)
Query: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
G + + C +G+F S G C PC C+ N + C +G C+ C +T GEH
Sbjct: 58 GRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNE-----CLDGSGYCVHCQRNTTGEH 109
Query: 1009 CQFCRFGYYGDALQ---QDCRKCVCN--YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063
C+ C GY GD+++ Q C+ C C +L E C + +C+C N G
Sbjct: 110 CEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKN-----GAVRCICNENYAGP 164
Query: 1064 NCDRCAPNTW--QLASGTGCDPCNCNA---AHSFGPSCNEFTGQCQ-CMPGFGGRTCSEC 1117
NC+RCAP + L G+ C C+C+ + C+E TGQC+ C+ G C C
Sbjct: 165 NCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Query: 1118 QELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR-CDKCT-------- 1166
++GD + C C+C CD TG+C+ EG E P CDKC
Sbjct: 225 APGYYGDARIAKNCAVCNCGGG-----PCDSVTGECL-EEGFEPPTGCDKCVWDLTDALR 278
Query: 1167 -------RGYSGVFPDCTPC------HQCFALWDVIIAELTNRTHRFLEKAKALKISGVI 1213
G SGV + ++ A ++ +L+ R +++ + ++I+
Sbjct: 279 LAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA--LRKIQINNAE 336
Query: 1214 GPYRETVDSVERKVSEI-----KDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQV- 1267
+ + VE V + K L Q + + + + L E+A + + E+ ++
Sbjct: 337 NTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKML 396
Query: 1268 ---------EVKLSDTTSQSNSTAKELDSLQ---TEAESLDNTVKELAEQLEFIKNSDIR 1315
++S+ + +E+ S Q T+ E +D +E E E + ++
Sbjct: 397 YYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVD---EEADEAYELLSQAESW 453
Query: 1316 GALDSITK-YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQ 1374
L + T+ F + LE + NA ++ ++Q+ ED+ ++ ++ +++Q
Sbjct: 454 QRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQ 513
Query: 1375 ARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE-----CGGPNCRTDEGERKCGGPG 1429
R+ +++ ++ ++ LS +A+ T P + SE + G D G +
Sbjct: 514 ERVREQM--EVVNMSLSTSADSL--TTPRLTLSELDDIIKNASGIYAEID-GAKSELQVK 568
Query: 1430 CGGLVTVAHNAWQKAMDLDQDV-----------------------LSALAEVEQLSKMVS 1466
L ++H+ Q+A+D QD+ L A E + VS
Sbjct: 569 LSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628
Query: 1467 EAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVAN 1526
EA A+ A + + I + ++ +E NL+ Q R Q A+ S EAVA+
Sbjct: 629 EANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVAD 686
Query: 1527 EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSAT 1586
+ + L + + V+ L E + + ++ ++ EEA R +
Sbjct: 687 --TSRRVGGALARKSALKTRLSDAVKQLQAAE--RGDAQQRLGQSRLITEEANRTTMEVQ 742
Query: 1587 DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQ 1646
+ TA M ++ Q A A + LT + + T+ +
Sbjct: 743 --QATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTV-EQKR 799
Query: 1647 RISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686
S + +++ ++ AQ A I+ + QSA +V
Sbjct: 800 PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 839
Score = 113 bits (282), Expect = 2e-24
Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%)
Query: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824
+G CD G+ + D +G C+ N G C +C G G P C+PC C
Sbjct: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
Query: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874
L N C G +C C + C+RC PG++G P +C+ C C+G++D
Sbjct: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195
Query: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
DCD VTG+C NC T G CERC GYYGD I +C C C GP
Sbjct: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247
Score = 93.6 bits (231), Expect = 2e-18
Identities = 77/241 (31%), Positives = 110/241 (45%), Gaps = 52/241 (21%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
C C G+++EC +DG G+C+ C+ NT G +CE C+D Y R A
Sbjct: 82 CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
C+ C C ++ +F + Y +G V C N G NCE+C P YY +P +
Sbjct: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178
Query: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444
+ C++C C +G+ + + CD T GQCR C N G C+ C G+
Sbjct: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228
Query: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND 503
Y D K+CA CN GG PCDS TG C + CD+C+ W L++
Sbjct: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDA 276
Query: 504 L 504
L
Sbjct: 277 L 277
Score = 83.2 bits (204), Expect = 2e-15
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%)
Query: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
S C C+CN +S C D G C CQ NT G +CE+C Y R
Sbjct: 76 SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
P FC+ C C P + C A +C C N G +C+ C G+Y
Sbjct: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176
Query: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504
CK C C+ + P CD TG C C R TG C++C P ++G +
Sbjct: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 505 DGCRPCDCDLGGALNNSCFAESGQC 529
C C+C GG C + +G+C
Sbjct: 236 KNCAVCNC--GG---GPCDSVTGEC 255
Score = 82.8 bits (203), Expect = 3e-15
Identities = 44/120 (36%), Positives = 60/120 (50%), Gaps = 14/120 (11%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843
+C C N G C RCAPG +G S CK C+C N C+ VTGQC +C
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213
Query: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCL 899
+ +C+RC PG++G +C C C G CD VTGECL + + C++C+
Sbjct: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECLE-EGFEPPTGCDKCV 270
Score = 68.6 bits (166), Expect = 5e-11
Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%)
Query: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457
CD G+ NE + S G C C+ N GEHC+ C +G+ D P C+
Sbjct: 82 CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131
Query: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511
C C PL + C + G C C G +C++C P ++G N L C+ CD
Sbjct: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188
Query: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
C N C +GQC +C + G +C PGYY
Sbjct: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 67.0 bits (162), Expect = 2e-10
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498
C GF+ S + C C CN N C +G+C +C+R TG+HC++CL +
Sbjct: 67 CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
Query: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548
G + C+PC C L N SC+ ++G +C C + G C PGYY
Sbjct: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 169 bits (427), Expect = 3e-41
Identities = 95/260 (36%), Positives = 131/260 (50%), Gaps = 31/260 (11%)
Query: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860
C+R A G P + +V P T + G ++C G H
Sbjct: 21 CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75
Query: 861 FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
C PC CNG++++C +G C++CQ T G +CE+CL GY GD I G+ C+PCPCP
Sbjct: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
Query: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
FA SCY+ ++ C+C+ Y G C+ CA GY+GNP +G +C+ C C
Sbjct: 136 --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191
Query: 981 NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035
N +DP E CD+ TG+C CL +T G C+ C GYYGDA + ++C VCN
Sbjct: 192 N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242
Query: 1036 VQEHCNGSDCQCDKATGQCL 1055
C G CD TG+CL
Sbjct: 243 ----CGGG--PCDSVTGECL 256
Score = 140 bits (352), Expect = 1e-32
Identities = 180/827 (21%), Positives = 328/827 (39%), Gaps = 127/827 (15%)
Query: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
G + + C +G+F S G C PC C+ N + C +G C+ C +T GEH
Sbjct: 58 GRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNE-----CLDGSGYCVHCQRNTTGEH 109
Query: 1009 CQFCRFGYYGDALQ---QDCRKCVCN--YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063
C+ C GY GD+++ Q C+ C C +L E C + +C+C N G
Sbjct: 110 CEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKN-----GAVRCICNENYAGP 164
Query: 1064 NCDRCAPNTW--QLASGTGCDPCNCNA---AHSFGPSCNEFTGQCQ-CMPGFGGRTCSEC 1117
NC+RCAP + L G+ C C+C+ + C+E TGQC+ C+ G C C
Sbjct: 165 NCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Query: 1118 QELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR--------CDKCT- 1166
++GD + C C+C CD TG+C+ EG E P CDKC
Sbjct: 225 APGYYGDARIAKNCAVCNCGGG-----PCDSVTGECL-EEGFEPPTGMDCPTISCDKCVW 278
Query: 1167 --------------RGYSGVFPDCTPC------HQCFALWDVIIAELTNRTHRFLEKAKA 1206
G SGV + ++ A ++ +L+ R +++ +
Sbjct: 279 DLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA--LRK 336
Query: 1207 LKISGVIGPYRETVDSVERKVSEI-----KDILAQSPAAEPLKNIGNLFEEAEKLIKDVT 1261
++I+ + + VE V + K L Q + + + + L E+A + +
Sbjct: 337 IQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQ 396
Query: 1262 EMMAQV----------EVKLSDTTSQSNSTAKELDSLQ---TEAESLDNTVKELAEQLEF 1308
E+ ++ ++S+ + +E+ S Q T+ E +D +E E E
Sbjct: 397 EINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVD---EEADEAYEL 453
Query: 1309 IKNSDIRGALDSITK-YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQF 1367
+ ++ L + T+ F + LE + NA ++ ++Q+ ED+ ++
Sbjct: 454 LSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQ 513
Query: 1368 KEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE-----CGGPNCRTDEGE 1422
++ +++Q R+ +++ ++ ++ LS +A+ T P + SE + G D G
Sbjct: 514 RDHEKQQERVREQM--EVVNMSLSTSADSL--TTPRLTLSELDDIIKNASGIYAEID-GA 568
Query: 1423 RKCGGPGCGGLVTVAHNAWQKAMDLDQDV-----------------------LSALAEVE 1459
+ L ++H+ Q+A+D QD+ L A E
Sbjct: 569 KSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYE 628
Query: 1460 QLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLD 1519
+ VSEA A+ A + + I + ++ +E NL+ Q R Q A+
Sbjct: 629 NIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESS 686
Query: 1520 SIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAK 1579
S EAVA+ + + L + + V+ L E + + ++ ++ EEA
Sbjct: 687 SDEAVAD--TSRRVGGALARKSALKTRLSDAVKQLQAAE--RGDAQQRLGQSRLITEEAN 742
Query: 1580 RASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEE 1639
R + + TA M ++ Q A A + LT + +
Sbjct: 743 RTTMEVQ--QATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLR 800
Query: 1640 TLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686
T+ + S + +++ ++ AQ A I+ + QSA +V
Sbjct: 801 TV-EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 846
Score = 113 bits (282), Expect = 2e-24
Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%)
Query: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824
+G CD G+ + D +G C+ N G C +C G G P C+PC C
Sbjct: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
Query: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874
L N C G +C C + C+RC PG++G P +C+ C C+G++D
Sbjct: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195
Query: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
DCD VTG+C NC T G CERC GYYGD I +C C C GP
Sbjct: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247
Score = 88.6 bits (218), Expect = 5e-17
Identities = 79/248 (31%), Positives = 112/248 (45%), Gaps = 59/248 (23%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
C C G+++EC +DG G+C+ C+ NT G +CE C+D Y R A
Sbjct: 82 CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
C+ C C ++ +F + Y +G V C N G NCE+C P YY +P +
Sbjct: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178
Query: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444
+ C++C C +G+ + + CD T GQCR C N G C+ C G+
Sbjct: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228
Query: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRL--VTGQ-----HCDQCLPE 496
Y D K+CA CN GG PCDS TG C + TG CD+C+
Sbjct: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV-- 277
Query: 497 HWGLSNDL 504
W L++ L
Sbjct: 278 -WDLTDAL 284
Score = 83.2 bits (204), Expect = 2e-15
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%)
Query: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
S C C+CN +S C D G C CQ NT G +CE+C Y R
Sbjct: 76 SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
P FC+ C C P + C A +C C N G +C+ C G+Y
Sbjct: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176
Query: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504
CK C C+ + P CD TG C C R TG C++C P ++G +
Sbjct: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 505 DGCRPCDCDLGGALNNSCFAESGQC 529
C C+C GG C + +G+C
Sbjct: 236 KNCAVCNC--GG---GPCDSVTGEC 255
Score = 79.7 bits (195), Expect = 2e-14
Identities = 42/105 (40%), Positives = 53/105 (50%), Gaps = 13/105 (12%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843
+C C N G C RCAPG +G S CK C+C N C+ VTGQC +C
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213
Query: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECL 884
+ +C+RC PG++G +C C C G CD VTGECL
Sbjct: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECL 256
Score = 68.6 bits (166), Expect = 5e-11
Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%)
Query: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457
CD G+ NE + S G C C+ N GEHC+ C +G+ D P C+
Sbjct: 82 CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131
Query: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511
C C PL + C + G C C G +C++C P ++G N L C+ CD
Sbjct: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188
Query: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
C N C +GQC +C + G +C PGYY
Sbjct: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 67.0 bits (162), Expect = 2e-10
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498
C GF+ S + C C CN N C +G+C +C+R TG+HC++CL +
Sbjct: 67 CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
Query: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548
G + C+PC C L N SC+ ++G +C C + G C PGYY
Sbjct: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 167 bits (424), Expect = 6e-41
Identities = 94/250 (37%), Positives = 124/250 (49%), Gaps = 35/250 (14%)
Query: 835 PVTGQCHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQ 887
P QC C G + C C G+ F +C PC C G CDP TG+C +
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-G 434
Query: 888 DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-C 946
D C C G+Y DP C+PCPC +G SC P T ++ C C
Sbjct: 435 DENPDIECADCPIGFYNDP--HDPRSCKPCPCHNG--------FSCSVMPETEEVVCNNC 484
Query: 947 DPGYIGSRCDDCASGYFGNPSEVGGS---CQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
PG G+RC+ CA GYFG+P G CQPCQC+NN+D + CD+ TGRCLKC+++
Sbjct: 485 PPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHN 544
Query: 1004 TEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPN 1059
T G +C C+ GY+GD L + CR C CN +G+ C ++ G C+C P
Sbjct: 545 TAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC--------RSDGTCVCKPG 596
Query: 1060 VIGQNCDRCA 1069
G NC+ A
Sbjct: 597 FGGPNCEHGA 606
Score = 159 bits (401), Expect = 3e-38
Identities = 184/810 (22%), Positives = 310/810 (38%), Gaps = 113/810 (13%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPSEVG--GSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001
C+C GY G C DCASGY + + +G G+C PC C ACD +TG C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
Query: 1002 YHTEGEHCQFCRFGYYGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCL--- 1057
+ + E C C G+Y D + C+ C C+ NG C T + +C
Sbjct: 436 ENPDIE-CADCPIGFYNDPHDPRSCKPCPCH---------NGFSCSVMPETEEVVCNNCP 485
Query: 1058 PNVIGQNCDRCAPNTWQLASGTG-----CDPCNCN--AAHSFGPSCNEFTGQC-QCMPGF 1109
P V G C+ CA + G C PC CN S +C+ TG+C +C+
Sbjct: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
Query: 1110 GGRTCSECQELFWGDPDV-----ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
G C +C+ ++GDP +CRAC+C+P G E C +S G CVC G GP C+
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE- 603
Query: 1165 CTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVE 1224
G F C C+ + + R + KA+ GV+ P E ++
Sbjct: 604 -----HGAF-SCPACYNQVKIQMDQFMQQLQRMEALISKAQG--GDGVV-PDTELEGRMQ 654
Query: 1225 RKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKE 1284
+ ++DIL + +E + ++L+ SQ NS
Sbjct: 655 QAEQALQDILRDAQISEGASR--------------------SLGLQLAKVRSQENSYQSR 694
Query: 1285 LDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNS 1344
LD L+ E V+ L Q + + +R IT+ Q+SL E +T P S
Sbjct: 695 LDDLKMTVE----RVRALGSQYQ----NRVRDTHRLITQ-MQLSLAESEASLGNTNIPAS 745
Query: 1345 TVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGA 1404
+ FK +E RL + + +A+ M T
Sbjct: 746 D--------------HYVGPNGFKSLAQEATRLAES--------HVESASNMEQLTRETE 783
Query: 1405 SCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKM 1464
S+ EG G G +V +K L Q QL++
Sbjct: 784 DYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQ----------QLTRE 833
Query: 1465 VSEAKLRADEAKQSAEDILLKTNATKEKMDKS--NEELRNLIKQIRNFLTQDSADLDSIE 1522
++A++ AD + Q + +L + + D+S EE + + ++ + + + +D +
Sbjct: 834 ATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFK 893
Query: 1523 AVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRAS 1582
+ + Q LQN + + LS+ + + ++ E +
Sbjct: 894 RTQKNLGNWK-EEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESIL 952
Query: 1583 KSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLF 1642
K+ + + D K EEA K + + A + Q + L S ++ ++
Sbjct: 953 KNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAG 1012
Query: 1643 NASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDG---ELDEKYK 1699
A + SE+E+ + L +A + A +EK + ++K +V+ L+ E D
Sbjct: 1013 EALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMD 1072
Query: 1700 KVENLIAKKTEESADARRKAEMLQNEAKTL 1729
V+ +I + + A+ +Q+ TL
Sbjct: 1073 AVQMVITEAQKVDTRAKNAGVTIQDTLNTL 1102
Score = 115 bits (288), Expect = 4e-25
Identities = 73/212 (34%), Positives = 92/212 (43%), Gaps = 30/212 (14%)
Query: 763 SALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSGCKP 820
SA L G C+ QG CDP+ G C C C G + P CKP
Sbjct: 404 SARLGPFGTCIPCNCQGG--GACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKP 461
Query: 821 CECHLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNG 871
C CH S + C +C GV +C+ C G++G P CQPCQCN
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNN 521
Query: 872 HAD-----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPC-PDGPD 924
+ D +CD +TG CL C T G C++C AGY+GDP+ D CR C C P G +
Sbjct: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
C D CVC PG+ G C+
Sbjct: 582 -----PVGCRSDG-----TCVCKPGFGGPNCE 603
Score = 114 bits (284), Expect = 1e-24
Identities = 81/234 (34%), Positives = 104/234 (44%), Gaps = 50/234 (21%)
Query: 307 LNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQ 366
L C LC LP A R + C+CN S C FD ++ TGN G C +C
Sbjct: 6 LGCCLCFSLL--LPAARATSRR----EVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCN 57
Query: 367 HNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC 426
NT G +CE+CK +Y+H ERD C C C+ GS + CD+ +G+C
Sbjct: 58 DNTDGIHCEKCKNGFYRHRERDR-----CLPCNCNSKGSLSAR-CDN---------SGRC 102
Query: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGC--------KSCACNPLGTIPGGNPCDSETGH 478
CK V G CD C GF+ L+ GC C C+P G PCD+ G
Sbjct: 103 SCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGI---AGPCDA--GR 154
Query: 479 CYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCR 532
C CK VTG+ CD+C ++ +LDG P C CF SCR
Sbjct: 155 CVCKPAVTGERCDRCRSGYY----NLDGGNPEGC-------TQCFCYGHSASCR 197
Score = 101 bits (252), Expect = 6e-21
Identities = 80/244 (32%), Positives = 108/244 (44%), Gaps = 37/244 (15%)
Query: 791 QCQCRPNVVGRTCNRCAPG----TFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQG 845
QC C G+ C CA G + GP G C PC C G+ C+P TG C+
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 846 VYARQCDRCLPGHWGFP----SCQPCQC-NGHADDCDPVTGE--CLNCQDYTMGHNCERC 898
+C C G + P SC+PC C NG + P T E C NC G CE C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 899 LAGYYGDPIIGSGDH-----CRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPGYIG 952
GY+GDP G+H C+PC C + D + +C D +T + L C+ + G
Sbjct: 497 ADGYFGDPF---GEHGPVRPCQPCQCNNNVDPSA--SGNC--DRLTGRCLKCIHNTA--G 547
Query: 953 SRCDDCASGYFGNP--SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQ 1010
CD C +GYFG+P C+ C C N ++P C + G C+ C G +C+
Sbjct: 548 IYCDQCKAGYFGDPLAPNPADKCRACNC--NPMGSEPVGC-RSDGTCV-CKPGFGGPNCE 603
Query: 1011 FCRF 1014
F
Sbjct: 604 HGAF 607
Score = 99.4 bits (246), Expect = 3e-20
Identities = 73/231 (31%), Positives = 102/231 (44%), Gaps = 41/231 (17%)
Query: 1009 CQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQC------DKATG---QCL-CLP 1058
C C F A + R+ VC+ CNG QC + TG +CL C
Sbjct: 8 CCLC-FSLLLPAARATSRREVCD--------CNGKSRQCIFDRELHRQTGNGFRCLNCND 58
Query: 1059 NVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118
N G +C++C ++ C PCNCN+ S C+ +G+C C PG G C C
Sbjct: 59 NTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCL 117
Query: 1119 ELFWGDPDVECRA--------CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY- 1169
F D C CDCDP GI P CD G+CVC V G RCD+C GY
Sbjct: 118 PGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
Query: 1170 --SGVFPD-CTPCH------QCFALWDVIIAELTNRTHRFLEKAKALKISG 1211
G P+ CT C C + + + ++T+ H+ ++ KA++ +G
Sbjct: 175 NLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG 225
Score = 89.7 bits (221), Expect = 2e-17
Identities = 51/158 (32%), Positives = 75/158 (47%), Gaps = 28/158 (17%)
Query: 992 KETG---RCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCD 1048
++TG RCL C +T+G HC+ C+ G+Y + C C CN G++ C+ S
Sbjct: 45 RQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNS----- 99
Query: 1049 KATGQCLCLPNVIGQNCDRCAPNTWQLASGTGC--------DPCNCNAAHSFGPSCNEFT 1100
G+C C P V G CDRC P + + + GC C+C+ A GP C+
Sbjct: 100 ---GRCSCKPGVTGARCDRCLPG-FHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--A 152
Query: 1101 GQCQCMPGFGGRTCSECQELFW----GDPDVECRACDC 1134
G+C C P G C C+ ++ G+P+ C C C
Sbjct: 153 GRCVCKPAVTGERCDRCRSGYYNLDGGNPE-GCTQCFC 189
Score = 88.6 bits (218), Expect = 5e-17
Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 397 RCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCK 456
R CD G + I D TG C N +G HC+ CK GFY D C
Sbjct: 25 REVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERD--RCL 82
Query: 457 SCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC--------R 508
C CN G++ CD+ +G C CK VTG CD+CLP L++ GC
Sbjct: 83 PCNCNSKGSLSA--RCDN-SGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
Query: 509 PCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
CDCD G + C ++G+C C+P + G +C+ GYY
Sbjct: 138 KCDCDPAG-IAGPC--DAGRCVCKPAVTGERCDRCRSGYY 174
Score = 83.2 bits (204), Expect = 2e-15
Identities = 69/260 (26%), Positives = 93/260 (35%), Gaps = 56/260 (21%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C+C KG C+ C Y R C CNC
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGP---FGTCIPCNCQ------------------- 419
Query: 358 SGGVCD----DCQHNTMGRN--CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
GG CD DC + C C +Y P DP C+ C C + G
Sbjct: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPH----DPRSCKPCPC------HNGFS 469
Query: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-------CKSCACNPLG 464
S + ++ C V G C++C +G++ DPFG C+ C CN
Sbjct: 470 CSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNNNV 523
Query: 465 TIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN 520
CD TG C C G +CDQC ++G N D CR C+C+ G+
Sbjct: 524 DPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPV 583
Query: 521 SCFAESGQCSCRPHMIGRQC 540
C ++ G C C+P G C
Sbjct: 584 GCRSD-GTCVCKPGFGGPNC 602
Score = 81.3 bits (199), Expect = 8e-15
Identities = 63/204 (30%), Positives = 89/204 (43%), Gaps = 37/204 (18%)
Query: 296 GHCMCRHNTKGLNCELC-MDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
G C + C C + FY+D P + R+ CK C C+ F +V T
Sbjct: 429 GDCYSGDENPDIECADCPIGFYND----PHDPRS---CKPCPCHNG-----FSCSVMPET 476
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC----DPAGSQNEGI 410
V VC++C G CE C Y+ P + C+ C C DP+ S N
Sbjct: 477 EEV---VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN--- 530
Query: 411 CDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY--DLSSEDPFGCKSCACNPLGTIP 467
CD T G+C +C N G +CD CK G++ L+ C++C CNP+G+ P
Sbjct: 531 CDRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEP 582
Query: 468 GGNPCDSETGHCYCKRLVTGQHCD 491
G C S+ G C CK G +C+
Sbjct: 583 VG--CRSD-GTCVCKPGFGGPNCE 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGC--------KPCE 822
L C C+ +GSLS+ CD N G+C C+P V G C+RC PG +GC C+
Sbjct: 82 LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
Query: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCNGHADDC 876
C G + C+ G+C C V +CDRC G++ C C C GH+ C
Sbjct: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 77.4 bits (189), Expect = 1e-13
Identities = 49/144 (34%), Positives = 67/144 (46%), Gaps = 15/144 (10%)
Query: 788 NGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQG 845
NG +C C N G C +C G + C PC C+ +GS++A C+ +G+C C G
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG 107
Query: 846 VYARQCDRCLPGHWGFPSCQPCQCNGHAD---DCDPV-------TGECLNCQDYTMGHNC 895
V +CDRCLPG Q D DCDP G C+ C+ G C
Sbjct: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCV-CKPAVTGERC 166
Query: 896 ERCLAGYYGDPIIGSGDHCRPCPC 919
+RC +GYY + G+ + C C C
Sbjct: 167 DRCRSGYY-NLDGGNPEGCTQCFC 189
Score = 75.9 bits (185), Expect = 3e-13
Identities = 63/208 (30%), Positives = 80/208 (38%), Gaps = 40/208 (19%)
Query: 838 GQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDC------DPVTGE---CLNCQD 888
G C CF + LP + C CNG + C TG CLNC D
Sbjct: 7 GCCLCFSLL--------LPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCND 58
Query: 889 YTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDP 948
T G +CE+C G+Y D C PC C +S + C C C P
Sbjct: 59 NTDGIHCEKCKNGFYRH---RERDRCLPCNC----NSKGSLSARCDNSG-----RCSCKP 106
Query: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA----CDKETGRCLKCLYHT 1004
G G+RCD C G+ + G Q + ++ DP CD GRC+ C
Sbjct: 107 GVTGARCDRCLPGF--HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCV-CKPAV 161
Query: 1005 EGEHCQFCRFGYYG--DALQQDCRKCVC 1030
GE C CR GYY + C +C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 65.1 bits (157), Expect = 6e-10
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 404 GSQNEGICDSYTDFSTGLIAG-------QCRCKLNVEGEHCDVCKEGFY-DLSSEDPFG- 454
G + G D+ T S ++G QC C + +G+ C C G+ D + PFG
Sbjct: 353 GEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT 412
Query: 455 CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDL 514
C C C GG CD +TG CY C C + +D C+PC C
Sbjct: 413 CIPCNCQ------GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHN 466
Query: 515 GGALNNSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
G + + E C +C P + G +C GY+
Sbjct: 467 GFSCSVMPETEEVVCNNCPPGVTGARCELCADGYF 501
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/169 (30%), Positives = 65/169 (38%), Gaps = 52/169 (30%)
Query: 833 CNPVTGQCHCFQ---GVYA-RQCDRCLPGHWGFPSCQPCQCNGHAD---DCDPVTGECLN 885
CN T HC + G Y R+ DRCLP C CN CD +G C +
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLP----------CNCNSKGSLSARCDN-SGRC-S 103
Query: 886 CQDYTMGHNCERCLAGYY---------GDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQD 936
C+ G C+RCL G++ ++ S C P D+GR
Sbjct: 104 CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGR--------- 154
Query: 937 PVTLQLACVCDPGYIGSRCDDCASGYF----GNPSEVGGSCQPCQCHNN 981
CVC P G RCD C SGY+ GNP C C C+ +
Sbjct: 155 -------CVCKPAVTGERCDRCRSGYYNLDGGNPE----GCTQCFCYGH 192
Score = 53.5 bits (127), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
C G HC++C + + D C PC+C+ G+L+ C SG+CSC+P + G +C
Sbjct: 56 CNDNTDGIHCEKCKNGFYR-HRERDRCLPCNCNSKGSLSARC-DNSGRCSCKPGVTGARC 113
Query: 541 NEVEPGYYFAT 551
+ PG++ T
Sbjct: 114 DRCLPGFHMLT 124
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 13/88 (14%)
Query: 1102 QCQCMPGFGGRTCSECQELFWGD-----PDVECRACDCDPRGIETPQCDQSTGQCVCVEG 1156
QC C G+ G+ C +C + D P C C+C G CD TG C G
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGD--CYSG 434
Query: 1157 VEGP--RCDKCTRGYSGVFPDCTPCHQC 1182
E P C C G+ D C C
Sbjct: 435 DENPDIECADCPIGFYNDPHDPRSCKPC 462
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 167 bits (424), Expect = 6e-41
Identities = 94/250 (37%), Positives = 124/250 (49%), Gaps = 35/250 (14%)
Query: 835 PVTGQCHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQ 887
P QC C G + C C G+ F +C PC C G CDP TG+C +
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-G 434
Query: 888 DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-C 946
D C C G+Y DP C+PCPC +G SC P T ++ C C
Sbjct: 435 DENPDIECADCPIGFYNDP--HDPRSCKPCPCHNG--------FSCSVMPETEEVVCNNC 484
Query: 947 DPGYIGSRCDDCASGYFGNPSEVGGS---CQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
PG G+RC+ CA GYFG+P G CQPCQC+NN+D + CD+ TGRCLKC+++
Sbjct: 485 PPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHN 544
Query: 1004 TEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPN 1059
T G +C C+ GY+GD L + CR C CN +G+ C ++ G C+C P
Sbjct: 545 TAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC--------RSDGTCVCKPG 596
Query: 1060 VIGQNCDRCA 1069
G NC+ A
Sbjct: 597 FGGPNCEHGA 606
Score = 162 bits (409), Expect = 4e-39
Identities = 191/857 (22%), Positives = 333/857 (38%), Gaps = 114/857 (13%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPSEVG--GSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001
C+C GY G C DCASGY + + +G G+C PC C ACD +TG C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
Query: 1002 YHTEGEHCQFCRFGYYGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCL--- 1057
+ + E C C G+Y D + C+ C C+ NG C T + +C
Sbjct: 436 ENPDIE-CADCPIGFYNDPHDPRSCKPCPCH---------NGFSCSVMPETEEVVCNNCP 485
Query: 1058 PNVIGQNCDRCAPNTWQLASGTG-----CDPCNCN--AAHSFGPSCNEFTGQC-QCMPGF 1109
P V G C+ CA + G C PC CN S +C+ TG+C +C+
Sbjct: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
Query: 1110 GGRTCSECQELFWGDPDV-----ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
G C +C+ ++GDP +CRAC+C+P G E C +S G CVC G GP C+
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE- 603
Query: 1165 CTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVE 1224
G F C C+ + + R + KA+ GV+ P E ++
Sbjct: 604 -----HGAF-SCPACYNQVKIQMDQFMQQLQRMEALISKAQG--GDGVV-PDTELEGRMQ 654
Query: 1225 RKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKE 1284
+ ++DIL + +E + ++L+ SQ NS
Sbjct: 655 QAEQALQDILRDAQISEGASR--------------------SLGLQLAKVRSQENSYQSR 694
Query: 1285 LDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNS 1344
LD L+ E V+ L Q + + +R IT+ Q+SL E +T P S
Sbjct: 695 LDDLKMTVE----RVRALGSQYQ----NRVRDTHRLITQ-MQLSLAESEASLGNTNIPAS 745
Query: 1345 TVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGA 1404
+ FK +E RL + + +A+ M T
Sbjct: 746 D--------------HYVGPNGFKSLAQEATRLAES--------HVESASNMEQLTRETE 783
Query: 1405 SCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKM 1464
S+ EG G G +V +K L Q QL++
Sbjct: 784 DYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQ----------QLTRE 833
Query: 1465 VSEAKLRADEAKQSAEDILLKTNATKEKMDKS--NEELRNLIKQIRNFLTQDSADLDSIE 1522
++A++ AD + Q + +L + + D+S EE + + ++ + + + +D +
Sbjct: 834 ATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFK 893
Query: 1523 AVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRAS 1582
+ + Q LQN + + LS+ + + ++ E +
Sbjct: 894 RTQKNLGNWK-EEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESIL 952
Query: 1583 KSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLF 1642
K+ + + D K EEA K + + A + Q + L S ++ ++
Sbjct: 953 KNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAG 1012
Query: 1643 NASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVE 1702
A + SE+E+ + L +A + A +EK + ++K +V +GEL+ K + +
Sbjct: 1013 EALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREV----EGELERKELEFD 1068
Query: 1703 NLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELA 1762
+ +A++ +N T+ N+ LL +++ ++ L Q+L+
Sbjct: 1069 TNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLS 1128
Query: 1763 RLEGEVRSLLKDISQKV 1779
R + ++ S L+ + ++
Sbjct: 1129 RAKTQINSQLRPMMSEL 1145
Score = 115 bits (288), Expect = 4e-25
Identities = 73/212 (34%), Positives = 92/212 (43%), Gaps = 30/212 (14%)
Query: 763 SALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSGCKP 820
SA L G C+ QG CDP+ G C C C G + P CKP
Sbjct: 404 SARLGPFGTCIPCNCQGG--GACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKP 461
Query: 821 CECHLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNG 871
C CH S + C +C GV +C+ C G++G P CQPCQCN
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNN 521
Query: 872 HAD-----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPC-PDGPD 924
+ D +CD +TG CL C T G C++C AGY+GDP+ D CR C C P G +
Sbjct: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
C D CVC PG+ G C+
Sbjct: 582 -----PVGCRSDG-----TCVCKPGFGGPNCE 603
Score = 114 bits (284), Expect = 1e-24
Identities = 81/234 (34%), Positives = 104/234 (44%), Gaps = 50/234 (21%)
Query: 307 LNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQ 366
L C LC LP A R + C+CN S C FD ++ TGN G C +C
Sbjct: 6 LGCCLCFSLL--LPAARATSRR----EVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCN 57
Query: 367 HNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC 426
NT G +CE+CK +Y+H ERD C C C+ GS + CD+ +G+C
Sbjct: 58 DNTDGIHCEKCKNGFYRHRERDR-----CLPCNCNSKGSLSAR-CDN---------SGRC 102
Query: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGC--------KSCACNPLGTIPGGNPCDSETGH 478
CK V G CD C GF+ L+ GC C C+P G PCD+ G
Sbjct: 103 SCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGI---AGPCDA--GR 154
Query: 479 CYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCR 532
C CK VTG+ CD+C ++ +LDG P C CF SCR
Sbjct: 155 CVCKPAVTGERCDRCRSGYY----NLDGGNPEGC-------TQCFCYGHSASCR 197
Score = 101 bits (252), Expect = 6e-21
Identities = 80/244 (32%), Positives = 108/244 (44%), Gaps = 37/244 (15%)
Query: 791 QCQCRPNVVGRTCNRCAPG----TFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQG 845
QC C G+ C CA G + GP G C PC C G+ C+P TG C+
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 846 VYARQCDRCLPGHWGFP----SCQPCQC-NGHADDCDPVTGE--CLNCQDYTMGHNCERC 898
+C C G + P SC+PC C NG + P T E C NC G CE C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 899 LAGYYGDPIIGSGDH-----CRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPGYIG 952
GY+GDP G+H C+PC C + D + +C D +T + L C+ + G
Sbjct: 497 ADGYFGDPF---GEHGPVRPCQPCQCNNNVDPSA--SGNC--DRLTGRCLKCIHNTA--G 547
Query: 953 SRCDDCASGYFGNP--SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQ 1010
CD C +GYFG+P C+ C C N ++P C + G C+ C G +C+
Sbjct: 548 IYCDQCKAGYFGDPLAPNPADKCRACNC--NPMGSEPVGC-RSDGTCV-CKPGFGGPNCE 603
Query: 1011 FCRF 1014
F
Sbjct: 604 HGAF 607
Score = 99.4 bits (246), Expect = 3e-20
Identities = 73/231 (31%), Positives = 102/231 (44%), Gaps = 41/231 (17%)
Query: 1009 CQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQC------DKATG---QCL-CLP 1058
C C F A + R+ VC+ CNG QC + TG +CL C
Sbjct: 8 CCLC-FSLLLPAARATSRREVCD--------CNGKSRQCIFDRELHRQTGNGFRCLNCND 58
Query: 1059 NVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118
N G +C++C ++ C PCNCN+ S C+ +G+C C PG G C C
Sbjct: 59 NTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCL 117
Query: 1119 ELFWGDPDVECRA--------CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY- 1169
F D C CDCDP GI P CD G+CVC V G RCD+C GY
Sbjct: 118 PGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
Query: 1170 --SGVFPD-CTPCH------QCFALWDVIIAELTNRTHRFLEKAKALKISG 1211
G P+ CT C C + + + ++T+ H+ ++ KA++ +G
Sbjct: 175 NLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG 225
Score = 89.7 bits (221), Expect = 2e-17
Identities = 51/158 (32%), Positives = 75/158 (47%), Gaps = 28/158 (17%)
Query: 992 KETG---RCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCD 1048
++TG RCL C +T+G HC+ C+ G+Y + C C CN G++ C+ S
Sbjct: 45 RQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNS----- 99
Query: 1049 KATGQCLCLPNVIGQNCDRCAPNTWQLASGTGC--------DPCNCNAAHSFGPSCNEFT 1100
G+C C P V G CDRC P + + + GC C+C+ A GP C+
Sbjct: 100 ---GRCSCKPGVTGARCDRCLPG-FHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--A 152
Query: 1101 GQCQCMPGFGGRTCSECQELFW----GDPDVECRACDC 1134
G+C C P G C C+ ++ G+P+ C C C
Sbjct: 153 GRCVCKPAVTGERCDRCRSGYYNLDGGNPE-GCTQCFC 189
Score = 88.6 bits (218), Expect = 5e-17
Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 397 RCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCK 456
R CD G + I D TG C N +G HC+ CK GFY D C
Sbjct: 25 REVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERD--RCL 82
Query: 457 SCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC--------R 508
C CN G++ CD+ +G C CK VTG CD+CLP L++ GC
Sbjct: 83 PCNCNSKGSLSA--RCDN-SGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
Query: 509 PCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
CDCD G + C ++G+C C+P + G +C+ GYY
Sbjct: 138 KCDCDPAG-IAGPC--DAGRCVCKPAVTGERCDRCRSGYY 174
Score = 83.2 bits (204), Expect = 2e-15
Identities = 69/260 (26%), Positives = 93/260 (35%), Gaps = 56/260 (21%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C+C KG C+ C Y R C CNC
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGP---FGTCIPCNCQ------------------- 419
Query: 358 SGGVCD----DCQHNTMGRN--CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
GG CD DC + C C +Y P DP C+ C C + G
Sbjct: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPH----DPRSCKPCPC------HNGFS 469
Query: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-------CKSCACNPLG 464
S + ++ C V G C++C +G++ DPFG C+ C CN
Sbjct: 470 CSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNNNV 523
Query: 465 TIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN 520
CD TG C C G +CDQC ++G N D CR C+C+ G+
Sbjct: 524 DPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPV 583
Query: 521 SCFAESGQCSCRPHMIGRQC 540
C ++ G C C+P G C
Sbjct: 584 GCRSD-GTCVCKPGFGGPNC 602
Score = 81.3 bits (199), Expect = 8e-15
Identities = 63/204 (30%), Positives = 89/204 (43%), Gaps = 37/204 (18%)
Query: 296 GHCMCRHNTKGLNCELC-MDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
G C + C C + FY+D P + R+ CK C C+ F +V T
Sbjct: 429 GDCYSGDENPDIECADCPIGFYND----PHDPRS---CKPCPCHNG-----FSCSVMPET 476
Query: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC----DPAGSQNEGI 410
V VC++C G CE C Y+ P + C+ C C DP+ S N
Sbjct: 477 EEV---VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN--- 530
Query: 411 CDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY--DLSSEDPFGCKSCACNPLGTIP 467
CD T G+C +C N G +CD CK G++ L+ C++C CNP+G+ P
Sbjct: 531 CDRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEP 582
Query: 468 GGNPCDSETGHCYCKRLVTGQHCD 491
G C S+ G C CK G +C+
Sbjct: 583 VG--CRSD-GTCVCKPGFGGPNCE 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGC--------KPCE 822
L C C+ +GSLS+ CD N G+C C+P V G C+RC PG +GC C+
Sbjct: 82 LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
Query: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCNGHADDC 876
C G + C+ G+C C V +CDRC G++ C C C GH+ C
Sbjct: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 77.4 bits (189), Expect = 1e-13
Identities = 49/144 (34%), Positives = 67/144 (46%), Gaps = 15/144 (10%)
Query: 788 NGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQG 845
NG +C C N G C +C G + C PC C+ +GS++A C+ +G+C C G
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG 107
Query: 846 VYARQCDRCLPGHWGFPSCQPCQCNGHAD---DCDPV-------TGECLNCQDYTMGHNC 895
V +CDRCLPG Q D DCDP G C+ C+ G C
Sbjct: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCV-CKPAVTGERC 166
Query: 896 ERCLAGYYGDPIIGSGDHCRPCPC 919
+RC +GYY + G+ + C C C
Sbjct: 167 DRCRSGYY-NLDGGNPEGCTQCFC 189
Score = 75.9 bits (185), Expect = 3e-13
Identities = 63/208 (30%), Positives = 80/208 (38%), Gaps = 40/208 (19%)
Query: 838 GQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDC------DPVTGE---CLNCQD 888
G C CF + LP + C CNG + C TG CLNC D
Sbjct: 7 GCCLCFSLL--------LPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCND 58
Query: 889 YTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDP 948
T G +CE+C G+Y D C PC C +S + C C C P
Sbjct: 59 NTDGIHCEKCKNGFYRH---RERDRCLPCNC----NSKGSLSARCDNSG-----RCSCKP 106
Query: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA----CDKETGRCLKCLYHT 1004
G G+RCD C G+ + G Q + ++ DP CD GRC+ C
Sbjct: 107 GVTGARCDRCLPGF--HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCV-CKPAV 161
Query: 1005 EGEHCQFCRFGYYG--DALQQDCRKCVC 1030
GE C CR GYY + C +C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 65.1 bits (157), Expect = 6e-10
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 404 GSQNEGICDSYTDFSTGLIAG-------QCRCKLNVEGEHCDVCKEGFY-DLSSEDPFG- 454
G + G D+ T S ++G QC C + +G+ C C G+ D + PFG
Sbjct: 353 GEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT 412
Query: 455 CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDL 514
C C C GG CD +TG CY C C + +D C+PC C
Sbjct: 413 CIPCNCQ------GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHN 466
Query: 515 GGALNNSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
G + + E C +C P + G +C GY+
Sbjct: 467 GFSCSVMPETEEVVCNNCPPGVTGARCELCADGYF 501
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/169 (30%), Positives = 65/169 (38%), Gaps = 52/169 (30%)
Query: 833 CNPVTGQCHCFQ---GVYA-RQCDRCLPGHWGFPSCQPCQCNGHAD---DCDPVTGECLN 885
CN T HC + G Y R+ DRCLP C CN CD +G C +
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLP----------CNCNSKGSLSARCDN-SGRC-S 103
Query: 886 CQDYTMGHNCERCLAGYY---------GDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQD 936
C+ G C+RCL G++ ++ S C P D+GR
Sbjct: 104 CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGR--------- 154
Query: 937 PVTLQLACVCDPGYIGSRCDDCASGYF----GNPSEVGGSCQPCQCHNN 981
CVC P G RCD C SGY+ GNP C C C+ +
Sbjct: 155 -------CVCKPAVTGERCDRCRSGYYNLDGGNPE----GCTQCFCYGH 192
Score = 53.5 bits (127), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
C G HC++C + + D C PC+C+ G+L+ C SG+CSC+P + G +C
Sbjct: 56 CNDNTDGIHCEKCKNGFYR-HRERDRCLPCNCNSKGSLSARC-DNSGRCSCKPGVTGARC 113
Query: 541 NEVEPGYYFAT 551
+ PG++ T
Sbjct: 114 DRCLPGFHMLT 124
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 13/88 (14%)
Query: 1102 QCQCMPGFGGRTCSECQELFWGD-----PDVECRACDCDPRGIETPQCDQSTGQCVCVEG 1156
QC C G+ G+ C +C + D P C C+C G CD TG C G
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGD--CYSG 434
Query: 1157 VEGP--RCDKCTRGYSGVFPDCTPCHQC 1182
E P C C G+ D C C
Sbjct: 435 DENPDIECADCPIGFYNDPHDPRSCKPC 462
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 162 bits (410), Expect = 3e-39
Identities = 131/421 (31%), Positives = 170/421 (40%), Gaps = 78/421 (18%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831
+C C G+ CD G C+C P V G C P + +G K C C +G
Sbjct: 567 SCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGY-YGKHCRKKCNCANRGR--- 618
Query: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGF-PSC-QPCQC-NGHADDCDPVTGECLNCQD 888
C+ + G C C G+Y R C P W F P C + CQC H CD G C +C+
Sbjct: 619 -CHRLYGACLCDPGLYGRFCHLTCP-PWAFGPGCSEECQCVQPHTQSCDKRDGSC-SCKA 675
Query: 889 YTMGHNCE-RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
G C+ C GY+G + C CP G +C D V+ + C
Sbjct: 676 GFRGERCQAECELGYFGPGC------WQACTCPVGV--------AC--DSVSGECGKRCP 719
Query: 948 PGYIGSRC-DDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEG 1006
G+ G C +C G FG SC CH TG+C +C G
Sbjct: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHG------------VTGQC-RCPPGRTG 766
Query: 1007 EHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC 1065
E C+ C G +G Q+ C C +H +CD TG CLCLP +G C
Sbjct: 767 EDCEADCPEGRWGLGCQEICPAC---------QHA----ARCDPETGACLCLPGFVGSRC 813
Query: 1066 DRCAPNTWQLASGTGCDP-CNC-NAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFW 1122
P W G C C+C N H C+ TG C C PG+ G +C C W
Sbjct: 814 QDVCPAGWY---GPSCQTRCSCANDGH-----CHPATGHCSCAPGWTGFSCQRACDTGHW 865
Query: 1123 GDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGVFPDCTPCHQ 1181
G PD C+C CD +G C+C G GPRC+ +C +G+ G P C Q
Sbjct: 866 G-PDCS-HPCNC---SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG--PGCEQRCQ 918
Query: 1182 C 1182
C
Sbjct: 919 C 919
Score = 162 bits (410), Expect = 3e-39
Identities = 143/497 (28%), Positives = 180/497 (36%), Gaps = 138/497 (27%)
Query: 770 GLAC-ECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGS 828
GL C E P ++ CDP G C C P VG C P + +GPS C C G
Sbjct: 779 GLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGW-YGPSCQTRCSCANDGH 837
Query: 829 VNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQ 887
C+P TG C C G C R C GHWG PC C+ CD ++G CL C+
Sbjct: 838 ----CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL-CE 892
Query: 888 DYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
+G CE+ C G++G G R C C G + AC C
Sbjct: 893 AGYVGPRCEQQCPQGHFGP-----GCEQR-CQCQHGAACDH------------VSGACTC 934
Query: 947 DPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCL------- 998
G+ G+ C+ C +G+FG C + + T ACD G CL
Sbjct: 935 PAGWRGTFCEHACPAGFFG-----------LDCRSACNCTAGAACDAVNGSCLCPAGRRG 983
Query: 999 -----KCLYHTEGEHC-------------------------------QFCRFGYYGDALQ 1022
C HT G +C Q C G YGD
Sbjct: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGD--- 1040
Query: 1023 QDCR-KCVCNYLGT---VQEHCN------GSDCQ-----------------------CDK 1049
+CR C+C GT V HC G C+ CD
Sbjct: 1041 -NCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDP 1099
Query: 1050 ATGQCLCLPNVIGQNCDRCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPG 1108
TG+CLC G C W G C C+C G +C+ TG C+C PG
Sbjct: 1100 HTGRCLCPAGWTGDKCQSPCLRGW---FGEACAQRCSCPP----GAACHHVTGACRCPPG 1152
Query: 1109 FGGRTCSE-CQELFWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRC-DKC 1165
F G C + C +G+ +C + C C E P C +TG C C G GP C +C
Sbjct: 1153 FTGSGCEQACPPGSFGE---DCAQMCQCPG---ENPACHPATGTCSCAAGYHGPSCQQRC 1206
Query: 1166 TRGYSGVFPDCTPCHQC 1182
G G P C C
Sbjct: 1207 PPGRYG--PGCEQLCGC 1221
Score = 159 bits (401), Expect = 3e-38
Identities = 129/405 (31%), Positives = 164/405 (40%), Gaps = 85/405 (20%)
Query: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSVN 830
+C C + C GQC+C P G C C G +G G P H
Sbjct: 743 SCSCG-----GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHA----- 792
Query: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQP-CQC--NGHADDCDPVTGECLNCQ 887
A C+P TG C C G +C P W PSCQ C C +GH C P TG C +C
Sbjct: 793 ARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGH---CHPATGHC-SCA 848
Query: 888 DYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
G +C+R C G++G D PC C G SC + C+C
Sbjct: 849 PGWTGFSCQRACDTGHWGP------DCSHPCNCSAGHG-------SC----DAISGLCLC 891
Query: 947 DPGYIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
+ GY+G RC+ C G+FG E Q CQC + ACD +G C C
Sbjct: 892 EAGYVGPRCEQQCPQGHFGPGCE-----QRCQCQHG------AACDHVSGAC-TCPAGWR 939
Query: 1006 GEHCQF-CRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063
G C+ C G++G DCR C C + CD G CLC G
Sbjct: 940 GTFCEHACPAGFFG----LDCRSACNCT-----------AGAACDAVNGSCLCPAGRRGP 984
Query: 1064 NC-DRCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQEL 1120
C + C +T+ G C C C G SC+ GQC C PG+ G +C + C
Sbjct: 985 RCAETCPAHTY----GHNCSQACAC----FNGASCDPVHGQCHCAPGWMGPSCLQACPAG 1036
Query: 1121 FWGDPDVECR-ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
+GD CR +C C G CD +G C C EG G C+K
Sbjct: 1037 LYGD---NCRHSCLCQNGG----TCDPVSGHCACPEGWAGLACEK 1074
Score = 158 bits (400), Expect = 4e-38
Identities = 147/471 (31%), Positives = 187/471 (39%), Gaps = 114/471 (24%)
Query: 770 GLACE--CDPQ----------GSLSS-VCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGP 815
GLACE C P+ G L+ +CDP+ G+C C G C C G FG
Sbjct: 1069 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG--E 1126
Query: 816 SGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHAD 874
+ + C C A C+ VTG C C G C++ C PG +G Q CQC G
Sbjct: 1127 ACAQRCSC----PPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP 1182
Query: 875 DCDPVTGECLNCQDYTMGHNC-ERCLAGYYG---DPIIG--SGDHC----RPCPCPDG-- 922
C P TG C +C G +C +RC G YG + + G +G C C CP G
Sbjct: 1183 ACHPATGTC-SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
Query: 923 -------PDSGRQFARSCYQ----------DPVTLQLACVCDPGYIGSRCD-DCASGYFG 964
GR F +C DPVT C+C PG G RC+ C FG
Sbjct: 1242 GTDCNLTCPQGR-FGPNCTHVCGCGQGAACDPVT--GTCLCPPGRAGVRCERGCPQNRFG 1298
Query: 965 NPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQ 1023
E C C N C G C C G HC+ C G YG A
Sbjct: 1299 VGCE-----HTCSCRNG------GLCHASNGSC-SCGLGWTGRHCELACPPGRYGAACHL 1346
Query: 1024 DCR--------------KCVCNYLGTVQEH-----CNGSDCQ----------CDKATGQC 1054
+C +C + G EH +G+ CQ CD +G+C
Sbjct: 1347 ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
Query: 1055 LCLPNVIGQNCDR-CAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
LC G C+R C P ++ G GC C+C+ G C+ TG C C PG G
Sbjct: 1407 LCPAGFHGHFCERGCEPGSF----GEGCHQRCDCDG----GAPCDPVTGLCLCPPGRSGA 1458
Query: 1113 TCS-ECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRC 1162
TC+ +C+ +G P CDC CD +GQC CV+G GP C
Sbjct: 1459 TCNLDCRRGQFG-PSCTLH-CDCGGGA----DCDPVSGQCHCVDGYMGPTC 1503
Score = 154 bits (389), Expect = 7e-37
Identities = 130/425 (30%), Positives = 171/425 (40%), Gaps = 78/425 (18%)
Query: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGCKPCECHLQGS 828
G + EC + CD G C C+ G C C G FGP + C C
Sbjct: 649 GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY--FGPGCWQACTC----P 702
Query: 829 VNAFCNPVTGQC--HCFQGVYARQC-DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLN 885
V C+ V+G+C C G C C G +G C C G C VTG+C
Sbjct: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGG--APCHGVTGQC-R 759
Query: 886 CQDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
C G +CE C G +G +G + C C Q A C DP T AC
Sbjct: 760 CPPGRTGEDCEADCPEGRWG---LGCQEICPAC----------QHAARC--DPET--GAC 802
Query: 945 VCDPGYIGSRCDD-CASGYFGNPSEVGGSCQP-CQCHNNIDTTDPEACDKETGRCLKCLY 1002
+C PG++GSRC D C +G++ G SCQ C C N+ C TG C C
Sbjct: 803 LCLPGFVGSRCQDVCPAGWY------GPSCQTRCSCAND------GHCHPATGHC-SCAP 849
Query: 1003 HTEGEHCQ-FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVI 1061
G CQ C G++G C +C+ CD +G CLC +
Sbjct: 850 GWTGFSCQRACDTGHWGPDCSHPC-------------NCSAGHGSCDAISGLCLCEAGYV 896
Query: 1062 GQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQEL 1120
G C++ P Q G GC+ C H G +C+ +G C C G+ G C C
Sbjct: 897 GPRCEQQCP---QGHFGPGCEQ-RCQCQH--GAACDHVSGACTCPAGWRGTFCEHACPAG 950
Query: 1121 FWGDPDVECR-ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRC-DKCTRGYSGVFPDCTP 1178
F+G ++CR AC+C CD G C+C G GPRC + C G +C+
Sbjct: 951 FFG---LDCRSACNCTAGA----ACDAVNGSCLCPAGRRGPRCAETCPAHTYG--HNCSQ 1001
Query: 1179 CHQCF 1183
CF
Sbjct: 1002 ACACF 1006
Score = 150 bits (380), Expect = 8e-36
Identities = 133/439 (30%), Positives = 171/439 (38%), Gaps = 85/439 (19%)
Query: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSV 829
G CE Q + CD G C C G C P F FG C C +
Sbjct: 910 GPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF-FGLDCRSACNC----TA 964
Query: 830 NAFCNPVTGQCHCFQGVYARQCDRCLPGH-WGFPSCQPCQCNGHADDCDPVTGECLNCQD 888
A C+ V G C C G +C P H +G Q C C A CDPV G+C +C
Sbjct: 965 GAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGAS-CDPVHGQC-HCAP 1022
Query: 889 YTMGHNC-ERCLAGYYGDP-----IIGSGDHCRP----CPCPDG--------------PD 924
MG +C + C AG YGD + +G C P C CP+G
Sbjct: 1023 GWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVR 1082
Query: 925 SGRQFARSCYQ----DPVTLQLACVCDPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCH 979
+G + + C DP T + C+C G+ G +C C G+FG SC P
Sbjct: 1083 AGCRHSGGCLNGGLCDPHTGR--CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP---- 1136
Query: 980 NNIDTTDPEACDKETGRCLKCLYHTEGEHC-QFCRFGYYGDALQQDCRKCVCNYLGTVQE 1038
AC TG C +C G C Q C G +G+ Q C+
Sbjct: 1137 -------GAACHHVTGAC-RCPPGFTGSGCEQACPPGSFGEDCAQMCQ------------ 1176
Query: 1039 HCNGSDCQCDKATGQCLCLPNVIGQNCD-RCAPNTWQLASGTGCDP-CNCNAAHSFGPSC 1096
C G + C ATG C C G +C RC P + G GC+ C C G SC
Sbjct: 1177 -CPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRY----GPGCEQLCGCLN----GGSC 1227
Query: 1097 NEFTGQCQCMPGFGGRTCS-ECQELFWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCV 1154
+ TG C+C GF G C+ C + +G C C C + CD TG C+C
Sbjct: 1228 DAATGACRCPTGFLGTDCNLTCPQGRFGP---NCTHVCGCG----QGAACDPVTGTCLCP 1280
Query: 1155 EGVEGPRCDK-CTRGYSGV 1172
G G RC++ C + GV
Sbjct: 1281 PGRAGVRCERGCPQNRFGV 1299
Score = 105 bits (263), Expect = 3e-22
Identities = 90/296 (30%), Positives = 111/296 (37%), Gaps = 63/296 (21%)
Query: 783 SVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCK-PCECHLQGSVNAFCNPVTGQC 840
+ CDP G C C P G C R C FG G C+ C C G C+ G C
Sbjct: 1268 AACDPVTGTCLCPPGRAGVRCERGCPQNRFGVG---CEHTCSCRNGG----LCHASNGSC 1320
Query: 841 HCFQGVYARQCD-RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCL 899
C G R C+ C PG +G C C+ ++ C+P TG C RC
Sbjct: 1321 SCGLGWTGRHCELACPPGRYGAACHLECSCHNNST-CEPATGTC-------------RCG 1366
Query: 900 AGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCA 959
G+YG +H PCP G F + Q Q CDP I RC C
Sbjct: 1367 PGFYGQAC----EH----PCPPG------FHGAGCQGLCWCQHGAPCDP--ISGRCL-CP 1409
Query: 960 SGYFGNPSEVGGSCQPCQ----CHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF-CRF 1014
+G+ G+ E G C+P CH D CD TG CL C G C CR
Sbjct: 1410 AGFHGHFCERG--CEPGSFGEGCHQRCDCDGGAPCDPVTGLCL-CPPGRSGATCNLDCRR 1466
Query: 1015 GYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAP 1070
G +G + C C G CD +GQC C+ +G C P
Sbjct: 1467 GQFGPSCTLHC-------------DCGGG-ADCDPVSGQCHCVDGYMGPTCREGGP 1508
Score = 104 bits (260), Expect = 7e-22
Identities = 83/248 (33%), Positives = 102/248 (41%), Gaps = 48/248 (19%)
Query: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGCKPCECHLQGS 828
G+ CE +C + G C C GR C C PG +G CHL+ S
Sbjct: 1298 GVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYG--------AACHLECS 1349
Query: 829 V--NAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLN 885
N+ C P TG C C G Y + C+ C PG G C C H CDP++G CL
Sbjct: 1350 CHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQ-HGAPCDPISGRCL- 1407
Query: 886 CQDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
C GH CER C G +G+ G H R C C G DPVT C
Sbjct: 1408 CPAGFHGHFCERGCEPGSFGE-----GCHQR-CDCDGGAPC----------DPVT--GLC 1449
Query: 945 VCDPGYIGSRCD-DCASGYFGNPSEVGGSCQ-PCQCHNNIDTTDPEACDKETGRCLKCLY 1002
+C PG G+ C+ DC G F G SC C C D CD +G+C C+
Sbjct: 1450 LCPPGRSGATCNLDCRRGQF------GPSCTLHCDCGGGAD------CDPVSGQC-HCVD 1496
Query: 1003 HTEGEHCQ 1010
G C+
Sbjct: 1497 GYMGPTCR 1504
Score = 91.7 bits (226), Expect = 6e-18
Identities = 81/254 (31%), Positives = 109/254 (42%), Gaps = 58/254 (22%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ-PCQCHNNIDTTDPEACDKETGRCLKCLY 1002
C C G+ G C++ P G +C C C N CD TG C +C
Sbjct: 540 CDCPEGWTGLICNETCP-----PDTFGKNCSFSCSCQNG------GTCDSVTGAC-RCPP 587
Query: 1003 HTEGEHCQF-CRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNV 1060
G +C+ C GYYG + CRK C C G +C + G CLC P +
Sbjct: 588 GVSGTNCEDGCPKGYYG----KHCRKKCNCANRG-----------RCHRLYGACLCDPGL 632
Query: 1061 IGQNCDRCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTC-SECQ 1118
G+ C P W A G GC + C C H+ SC++ G C C GF G C +EC+
Sbjct: 633 YGRFCHLTCP-PW--AFGPGCSEECQCVQPHT--QSCDKRDGSCSCKAGFRGERCQAECE 687
Query: 1119 ELFWGDPDVEC-RACDCDPRGIETPQCDQSTGQC--VCVEGVEGPRC-DKCTRGYSGVFP 1174
++G C +AC C P G+ CD +G+C C G +G C +C G GV
Sbjct: 688 LGYFGP---GCWQACTC-PVGV---ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGV-- 738
Query: 1175 DCT--------PCH 1180
+C+ PCH
Sbjct: 739 NCSSSCSCGGAPCH 752
Score = 75.9 bits (185), Expect = 3e-13
Identities = 82/288 (28%), Positives = 103/288 (35%), Gaps = 77/288 (26%)
Query: 294 VHGHCMCRHNTKGLNCEL-CMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYL 352
V G C C G NCE C Y+ R KKCNC CH L
Sbjct: 579 VTGACRCPPGVSGTNCEDGCPKGYYGKHCR----------KKCNCANRG-RCHRLYGACL 627
Query: 353 ATGNVSGGVCD-DCQHNTMGRNC-EQCKPFYYQHPERDIRD------------------- 391
+ G C C G C E+C+ D RD
Sbjct: 628 CDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECE 687
Query: 392 -----PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC--RCKLNVEGEHC-DVCKEG 443
P + CTC P G CDS ++G+C RC +GE C C G
Sbjct: 688 LGYFGPGCWQACTC-PVGVA----CDS--------VSGECGKRCPAGFQGEDCGQECPVG 734
Query: 444 FYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPE-HWGLSN 502
+ ++ SC+C GG PC TG C C TG+ C+ PE WGL
Sbjct: 735 TFGVNCSS-----SCSC-------GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL-- 780
Query: 503 DLDGCRP-CDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEP-GYY 548
GC+ C A C E+G C C P +G +C +V P G+Y
Sbjct: 781 ---GCQEICPACQHAA---RCDPETGACLCLPGFVGSRCQDVCPAGWY 822
Score = 73.9 bits (180), Expect = 1e-12
Identities = 66/252 (26%), Positives = 85/252 (33%), Gaps = 62/252 (24%)
Query: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
GHC C G +C+ D H W P + CNC+ SC + L
Sbjct: 843 GHCSCAPGWTGFSCQRACDTGH---WGP------DCSHPCNCSAGHGSCDAISGLCLCEA 893
Query: 356 NVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
G C+ C G CEQ RC C Q+ CD
Sbjct: 894 GYVGPRCEQQCPQGHFGPGCEQ--------------------RCQC-----QHGAACDH- 927
Query: 415 TDFSTGLIAGQCRCKLNVEGEHCD-VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
++G C C G C+ C GF+ L C+S ACN G CD
Sbjct: 928 -------VSGACTCPAGWRGTFCEHACPAGFFGLD------CRS-ACN----CTAGAACD 969
Query: 474 SETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
+ G C C G C + P H + + + C C G SC GQC C P
Sbjct: 970 AVNGSCLCPAGRRGPRCAETCPAH---TYGHNCSQACACFNGA----SCDPVHGQCHCAP 1022
Query: 534 HMIGRQCNEVEP 545
+G C + P
Sbjct: 1023 GWMGPSCLQACP 1034
Score = 68.2 bits (165), Expect = 7e-11
Identities = 83/302 (27%), Positives = 107/302 (35%), Gaps = 82/302 (27%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSN 330
C C G + C PV G C+C G+ CE P + R
Sbjct: 1262 CGC-GQGAACDPVTGT-----------CLCPPGRAGVRCE------RGCP----QNRFGV 1299
Query: 331 ACKK-CNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCE-QCKPFYYQ---HP 385
C+ C+C + CH S G C C GR+CE C P Y H
Sbjct: 1300 GCEHTCSCRNGGL-CH-----------ASNGSCS-CGLGWTGRHCELACPPGRYGAACHL 1346
Query: 386 ERDIRDPNFCE----RCTCDPA---------------GSQNEGICDSYTDFSTGLIAGQC 426
E + + CE C C P G+ +G+C I+G+C
Sbjct: 1347 ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
Query: 427 RCKLNVEGEHCDV-CKEGFYDLSSEDPFGC-KSCACNPLGTIPGGNPCDSETGHCYCKRL 484
C G C+ C+ G + GC + C C+ GG PCD TG C C
Sbjct: 1407 LCPAGFHGHFCERGCEPGSFGE------GCHQRCDCD------GGAPCDPVTGLCLCPPG 1454
Query: 485 VTGQHCD-QCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEV 543
+G C+ C +G S L CDC GGA C SGQC C +G C E
Sbjct: 1455 RSGATCNLDCRRGQFGPSCTLH----CDCG-GGA---DCDPVSGQCHCVDGYMGPTCREG 1506
Query: 544 EP 545
P
Sbjct: 1507 GP 1508
Score = 65.9 bits (159), Expect = 3e-10
Identities = 84/353 (23%), Positives = 120/353 (33%), Gaps = 80/353 (22%)
Query: 268 RGNCFCYGHASECAPVDGFNEEVEGMVHGHCM-----------CRHNTKGLNCELCMDFY 316
R +C C + C PV G EG C CRH+ LN LC D +
Sbjct: 1043 RHSCLCQ-NGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLC-DPH 1100
Query: 317 HDLPWRPA------------EGRNSNAC-KKCNCNEHSISCHFDMAVYLATGNVSGGVCD 363
PA G AC ++C+C + H A G G
Sbjct: 1101 TGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQ 1160
Query: 364 DCQHNTMGRNCEQCKPFYYQHPE-----------RDIRDPNFCERCTCDPAGSQNEGICD 412
C + G +C Q ++P P+ +RC G E +C
Sbjct: 1161 ACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG 1220
Query: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDV-CKEGFYDLSSEDPFGC-KSCACNPL-GTI--- 466
S G CRC G C++ C +G + + GC + AC+P+ GT
Sbjct: 1221 CLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCP 1280
Query: 467 PG---------------------------GNPCDSETGHCYCKRLVTGQHCD-QCLPEHW 498
PG G C + G C C TG+HC+ C P +
Sbjct: 1281 PGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRY 1340
Query: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC-NEVEPGYYFA 550
G + L+ C C N++C +G C C P G+ C + PG++ A
Sbjct: 1341 GAACHLE----CSCHN----NSTCEPATGTCRCGPGFYGQACEHPCPPGFHGA 1385
Score = 64.3 bits (155), Expect = 1e-09
Identities = 80/311 (25%), Positives = 104/311 (33%), Gaps = 99/311 (31%)
Query: 267 VRGNCFC-----------------YGH--ASECAPVDGFNEEVEGMVHGHCMCRHNTKGL 307
V G+C C YGH + CA +G + + VHG C C G
Sbjct: 971 VNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDP---VHGQCHCAPGWMGP 1027
Query: 308 NCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD--- 364
+C L PA N C C +GG CD
Sbjct: 1028 SC---------LQACPAGLYGDNCRHSCLCQ-------------------NGGTCDPVSG 1059
Query: 365 ---CQHNTMGRNCE-QCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTG 420
C G CE +C P RD+R C G N G+CD +T
Sbjct: 1060 HCACPEGWAGLACEKECLP-------RDVRAG--CRHS----GGCLNGGLCDPHT----- 1101
Query: 421 LIAGQCRCKLNVEGEHCDV-CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC 479
G+C C G+ C C G++ + + C+C P G C TG C
Sbjct: 1102 ---GRCLCPAGWTGDKCQSPCLRGWFGEAC-----AQRCSCPP------GAACHHVTGAC 1147
Query: 480 YCKRLVTGQHCDQ-CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGR 538
C TG C+Q C P +G D + C C N +C +G CSC G
Sbjct: 1148 RCPPGFTGSGCEQACPPGSFG----EDCAQMCQCP---GENPACHPATGTCSCAAGYHGP 1200
Query: 539 QCNE-VEPGYY 548
C + PG Y
Sbjct: 1201 SCQQRCPPGRY 1211
Score = 63.5 bits (153), Expect = 2e-09
Identities = 66/261 (25%), Positives = 87/261 (33%), Gaps = 67/261 (25%)
Query: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK-CNCNEHSISCHFDMAVYL 352
V G C C G +CE D P EGR C++ C +H+ C + L
Sbjct: 754 VTGQCRCPPGRTGEDCEA------DCP----EGRWGLGCQEICPACQHAARCDPETGACL 803
Query: 353 ATGNVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
G C D C G +C+ RC+C N+G C
Sbjct: 804 CLPGFVGSRCQDVCPAGWYGPSCQT--------------------RCSC-----ANDGHC 838
Query: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCD-VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGN 470
T G C C G C C G + P C + G
Sbjct: 839 HPAT--------GHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSA----------GHG 880
Query: 471 PCDSETGHCYCKRLVTGQHCDQCLPE-HWGLSNDLDGC-RPCDCDLGGALNNSCFAESGQ 528
CD+ +G C C+ G C+Q P+ H+G GC + C C G A C SG
Sbjct: 881 SCDAISGLCLCEAGYVGPRCEQQCPQGHFG-----PGCEQRCQCQHGAA----CDHVSGA 931
Query: 529 CSCRPHMIGRQCNEVEPGYYF 549
C+C G C P +F
Sbjct: 932 CTCPAGWRGTFCEHACPAGFF 952
Score = 62.0 bits (149), Expect = 5e-09
Identities = 65/247 (26%), Positives = 85/247 (34%), Gaps = 74/247 (29%)
Query: 311 LCMD--FYHDLPWRPAEGRNSNAC----KKCNCNEHSISCHFDMAVYLATGNVSGGVCDD 364
+C+D F HD + RN C C+C E +G +C++
Sbjct: 510 VCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPE----------------GWTGLICNE 553
Query: 365 -CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIA 423
C +T G+NC C+C QN G CDS T
Sbjct: 554 TCPPDTFGKNCSFS--------------------CSC-----QNGGTCDSVT-------- 580
Query: 424 GQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCK 482
G CRC V G +C D C +G+Y K C C G C G C C
Sbjct: 581 GACRCPPGVSGTNCEDGCPKGYYGKHCR-----KKCNCANRGR------CHRLYGACLCD 629
Query: 483 RLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCN- 541
+ G+ C P W GC +C SC G CSC+ G +C
Sbjct: 630 PGLYGRFCHLTCPP-WAFG---PGCSE-ECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA 684
Query: 542 EVEPGYY 548
E E GY+
Sbjct: 685 ECELGYF 691
Score = 59.3 bits (142), Expect = 3e-08
Identities = 119/474 (25%), Positives = 163/474 (34%), Gaps = 125/474 (26%)
Query: 791 QCQCRPNVV----GRTCNRCAPGTFGFGPS--------GCKPCECHLQGSVNAFCNPVTG 838
+CQCRP GR C R +P G G CECH+ + A
Sbjct: 226 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
Query: 839 QCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHAD------DCDPVTGECLNCQDYTMG 892
C G+ A+ CL F C C+ + C + E +N + G
Sbjct: 286 VDECAAGL-AQCAHGCLNTQGSFK----CVCHAGYELGADGRQCYRIEMEIVNSCEANNG 340
Query: 893 ---HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQ-----DPVTLQLAC 944
H C AG P+ C CP G + R+C D Q C
Sbjct: 341 GCSHGCSHTSAG----PL---------CTCPRGYELDTD-QRTCIDVDDCADSPCCQQVC 386
Query: 945 VCDPG------YIGSRC----------DDCASGYFG---NPSEVGGSCQPCQCHNNIDT- 984
+PG Y G R D+CAS G + + + GS Q C C
Sbjct: 387 TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQ-CSCEAGYRLH 445
Query: 985 TDPEAC----------DKETG--RCLKCLYHTEGEHCQFCRFGYYG-DALQQDCR----- 1026
D C D E R L + + E Q + G D + + R
Sbjct: 446 EDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTL 505
Query: 1027 --KCVCNYLGTVQEHCNGSDCQ--CDKATGQCLCLPNVIGQNC----------DRCAPNT 1072
K VC + G DC CD CL + G +C + C P+T
Sbjct: 506 TEKFVC------LDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDT 559
Query: 1073 WQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFWGDPDVECR 1130
+ G C C+C G +C+ TG C+C PG G C + C + ++G CR
Sbjct: 560 F----GKNCSFSCSCQN----GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGK---HCR 608
Query: 1131 -ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGVFPDCTPCHQC 1182
C+C RG +C + G C+C G+ G C C G P C+ QC
Sbjct: 609 KKCNCANRG----RCHRLYGACLCDPGLYGRFCHLTCPPWAFG--PGCSEECQC 656
Score = 50.8 bits (120), Expect = 1e-05
Identities = 49/143 (34%), Positives = 61/143 (42%), Gaps = 32/143 (22%)
Query: 421 LIAGQCR----CKLNVEGEHCDVCKEGFYDLSSE-----DPFG--CK-SCACNPLGTIPG 468
L CR C L ++G CD C EG+ L D FG C SC+C GT
Sbjct: 522 LTCDDCRNGGTCLLGLDG--CD-CPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGT--- 575
Query: 469 GNPCDSETGHCYCKRLVTGQHC-DQCLPEHWGLSNDLDGCR-PCDCDLGGALNNSCFAES 526
CDS TG C C V+G +C D C ++G CR C+C A C
Sbjct: 576 ---CDSVTGACRCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNC----ANRGRCHRLY 623
Query: 527 GQCSCRPHMIGRQCNEVEPGYYF 549
G C C P + GR C+ P + F
Sbjct: 624 GACLCDPGLYGRFCHLTCPPWAF 646
Score = 45.4 bits (106), Expect = 5e-04
Identities = 93/381 (24%), Positives = 122/381 (32%), Gaps = 91/381 (23%)
Query: 801 RTCNRCAPGTFGF-GPSGCKPCECHLQGSVNAF-CNPVTGQ-CHCFQGVYARQC----DR 853
RT RC G GC EC + C P + Q CHC G +C D
Sbjct: 105 RTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDE 164
Query: 854 CLPGHWGF-------PSCQPCQCNG----HADD--------CDPVTGECLN-CQDYTMGH 893
C + G P C+C H D C G C + C T+
Sbjct: 165 CRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITR 224
Query: 894 NCERCLAGYYGDPIIGSGDHC-RPCPCPDGPDSGRQFARSCYQDPVTLQLA-CVCDPGYI 951
+ +C G+ + G HC R PC + S ++ V LA C C GY
Sbjct: 225 HRCQCRPGFQ---LQEDGRHCVRRSPCANRNGS------CMHRCQVVRGLARCECHVGYQ 275
Query: 952 ----GSRCDD---CASGYFGNPSEVGGSCQ------PCQCHNN------------IDTTD 986
G C+D CA+G ++ C C CH I+
Sbjct: 276 LAADGKACEDVDECAAGL----AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEI 331
Query: 987 PEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQ 1046
+C+ G C HT C GY D Q+ C + DC
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC--------------IDVDDC- 376
Query: 1047 CDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFG--PSCNEFTG--Q 1102
D Q +C N G C C A G GC+ + A+ G C G Q
Sbjct: 377 ADSPCCQQVCTNNPGGYECG-CYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQ 435
Query: 1103 CQCMPGF----GGRTCSECQE 1119
C C G+ R CS +E
Sbjct: 436 CSCEAGYRLHEDRRGCSPLEE 456
Score = 44.7 bits (104), Expect = 8e-04
Identities = 59/234 (25%), Positives = 81/234 (34%), Gaps = 43/234 (18%)
Query: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACK-KCNCNEHSISCHFDMAVYLA 353
+G C C G +CEL GR AC +C+C+ +S +C
Sbjct: 1317 NGSCSCGLGWTGRHCELACP----------PGRYGAACHLECSCHNNS-TCEPATGTCRC 1365
Query: 354 TGNVSGGVCDD-CQHNTMGRNCE---------QCKPFYYQHPERDIRDPNFCERCTCDPA 403
G C+ C G C+ C P + +FCER C+P
Sbjct: 1366 GPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCER-GCEP- 1423
Query: 404 GSQNEGI---CDSYTDFSTGLIAGQCRCKLNVEGEHCDV-CKEGFYDLSSEDPFGCKSCA 459
GS EG CD + G C C G C++ C+ G + P C
Sbjct: 1424 GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG-----PSCTLHCD 1478
Query: 460 CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ----CLPEHWGLSNDLDGCRP 509
C GG CD +G C+C G C + LPE+ L+ G P
Sbjct: 1479 CG------GGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLP 1526
Score = 35.0 bits (79), Expect = 0.65
Identities = 74/318 (23%), Positives = 103/318 (32%), Gaps = 80/318 (25%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK------CNCNEHSISCHFDMAVY 351
C C +G C+ +D R G + C C C H D
Sbjct: 147 CHCPPGFQGPRCQYDVD-----ECRTHNGGCQHRCVNTPGSYLCECKP-GFRLHTDSRTC 200
Query: 352 LATGNVS---GGVCDDCQHNTMGRNCEQCKP-FYYQHPERDI--RDP---------NFCE 396
LA + + GG C T+ R+ QC+P F Q R R P + C+
Sbjct: 201 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQ 260
Query: 397 ------RCTCDPAGSQ---NEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
RC C G Q + C+ + + GL C LN +G VC G Y+L
Sbjct: 261 VVRGLARCECH-VGYQLAADGKACEDVDECAAGLAQCAHGC-LNTQGSFKCVCHAG-YEL 317
Query: 448 SSED---------------------PFGCKSCACNPLGTIPGGNPCDSETGHCY------ 480
++ GC + PL T P G D++ C
Sbjct: 318 GADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA 377
Query: 481 ----CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSC------FAESGQCS 530
C+++ T + G DGC D D + C A S QCS
Sbjct: 378 DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCS 437
Query: 531 C----RPHMIGRQCNEVE 544
C R H R C+ +E
Sbjct: 438 CEAGYRLHEDRRGCSPLE 455
Score = 33.9 bits (76), Expect = 1.5
Identities = 22/62 (35%), Positives = 23/62 (37%), Gaps = 9/62 (14%)
Query: 755 CRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFG 814
CR F S LH CD G CDP GQC C +G TC P
Sbjct: 1464 CRRGQFGPSCTLH-------CDCGGGAD--CDPVSGQCHCVDGYMGPTCREGGPLRLPEN 1514
Query: 815 PS 816
PS
Sbjct: 1515 PS 1516
Score = 32.7 bits (73), Expect = 3.2
Identities = 27/80 (33%), Positives = 32/80 (40%), Gaps = 12/80 (15%)
Query: 1067 RCAPNTWQLASGTGCDPCNCNAAHSF-GPSCNEFTGQ-CQCMPGFGGRTCSECQELFWGD 1124
RC Q GC C+A+ F G C + Q C C PGF G C D
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQY-------D 161
Query: 1125 PDVECRACD--CDPRGIETP 1142
D ECR + C R + TP
Sbjct: 162 VD-ECRTHNGGCQHRCVNTP 180
Score = 32.7 bits (73), Expect = 3.2
Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 18/119 (15%)
Query: 447 LSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHC----DQCLPEHWGLSN 502
+ D GC S C+ GG C+C G C D+C + G +
Sbjct: 115 MQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH 174
Query: 503 ---DLDGCRPCDCDLGGALN---------NSCFAESGQCS--CRPHMIGRQCNEVEPGY 547
+ G C+C G L+ NSC +G C C I R + PG+
Sbjct: 175 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF 233
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 161 bits (407), Expect = 6e-39
Identities = 124/389 (31%), Positives = 161/389 (41%), Gaps = 70/389 (17%)
Query: 792 CQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQC 851
CQC P G C+ G +GP C+C A CNP+TG CHC G +C
Sbjct: 124 CQCEPGWGGTNCSSACDGDH-WGPHCTSRCQC----KNGALCNPITGACHCAAGFRGWRC 178
Query: 852 -DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGS 910
DRC G +G Q CQC A CD VTGEC YT + C G +
Sbjct: 179 EDRCEQGTYGNDCHQRCQCQNGA-TCDHVTGECRCPPGYTGAFCEDLCPPGKH------- 230
Query: 911 GDHC-RPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRC-DDCASGYFGNPSE 968
G C + CPC +G C+ VT + C C G++G+ C C G FG
Sbjct: 231 GPQCEQRCPCQNG--------GVCHH--VTGE--CSCPSGWMGTVCGQPCPEGRFGK--- 275
Query: 969 VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQ-FCRFGYYGDALQQDCRK 1027
Q CQCHN CD TG+C C GE CQ C G YG + C +
Sbjct: 276 --NCSQECQCHNG------GTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLCAETC-Q 325
Query: 1028 CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR--CAPNTWQLASGTGCDPCN 1085
CV NG +C +G CLC G+ C+ C + + C PC+
Sbjct: 326 CV-----------NGG--KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC-PCH 371
Query: 1086 CNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFWGDPDVECRACDCDPRGIETPQC 1144
H SC+ +G+C C PG+ G C+E C F+G+ + +C C
Sbjct: 372 LENTH----SCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQ------NGADC 421
Query: 1145 DQSTGQCVCVEGVEGPRCD-KCTRGYSGV 1172
D TG+C C G +G C C G G+
Sbjct: 422 DSVTGKCTCAPGFKGIDCSTPCPLGTYGI 450
Score = 160 bits (406), Expect = 8e-39
Identities = 132/421 (31%), Positives = 171/421 (40%), Gaps = 85/421 (20%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSVNA 831
C C G VC G+C C +G C + C G FG S + C+CH G+
Sbjct: 238 CPCQNGG----VCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCS--QECQCHNGGT--- 288
Query: 832 FCNPVTGQCHCFQGVYARQC-DRCLPGHWGFPSCQPCQC-NGHADDCDPVTGECLNCQDY 889
C+ TGQCHC G +C D C G +G + CQC NG C V+G CL C+
Sbjct: 289 -CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG--GKCYHVSGACL-CEAG 344
Query: 890 TMGHNCER--CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
G CE C G YG + CPC + SC+ + C C
Sbjct: 345 FAGERCEARLCPEGLYGIKC------DKRCPC------HLENTHSCH----PMSGECACK 388
Query: 948 PGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEG 1006
PG+ G C++ C+ G++G + Q C C N D CD TG+C C +G
Sbjct: 389 PGWSGLYCNETCSPGFYGEACQ-----QICSCQNGAD------CDSVTGKC-TCAPGFKG 436
Query: 1007 EHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC 1065
C C G YG +C C +D C G C C G +C
Sbjct: 437 IDCSTPCPLGTYGINCSS---RCGCK-----------NDAVCSPVDGSCTCKAGWHGVDC 482
Query: 1066 D-RCAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQELFW 1122
RC TW G GC+ C C G +CN G C C PG+ G C CQ+ +
Sbjct: 483 SIRCPSGTW----GFGCNLTCQC----LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTY 534
Query: 1123 GDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-CTRGYSGVFPDCT-PC 1179
G + C CDC C +TG C C+ G G CD C G G P+C+ PC
Sbjct: 535 G---LNCAERCDCS----HADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWG--PNCSLPC 585
Query: 1180 H 1180
+
Sbjct: 586 Y 586
Score = 143 bits (360), Expect = 2e-33
Identities = 132/453 (29%), Positives = 168/453 (37%), Gaps = 121/453 (26%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTC-NRCAPGTFG------------------- 812
C+C G+ CD GQC C P G C + C GT+G
Sbjct: 281 CQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVS 336
Query: 813 -----------------------FGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYAR 849
+G K C CHL+ + + C+P++G+C C G
Sbjct: 337 GACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS--CHPMSGECACKPGWSGL 394
Query: 850 QC-DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCER-CLAGYYGDPI 907
C + C PG +G Q C C A DCD VTG+C C G +C C G YG
Sbjct: 395 YCNETCSPGFYGEACQQICSCQNGA-DCDSVTGKC-TCAPGFKGIDCSTPCPLGTYG--- 449
Query: 908 IGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQL--ACVCDPGYIGSRCD-DCASGYFG 964
I C C D V + +C C G+ G C C SG +G
Sbjct: 450 INCSSRC-----------------GCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG 492
Query: 965 NPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQ 1023
G CQC N AC+ G C C GE C+ C+ G YG
Sbjct: 493 -----FGCNLTCQCLNG------GACNTLDGTC-TCAPGWRGEKCELPCQDGTYG---LN 537
Query: 1024 DCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR-CAPNTWQLASGTGCD 1082
+C C+ H +G C TG C CLP G +CD CA W G C
Sbjct: 538 CAERCDCS-------HADG----CHPTTGHCRCLPGWSGVHCDSVCAEGRW----GPNCS 582
Query: 1083 -PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFWGDPDVECRACDCDPRGIE 1140
PC C G SC+ G C+C PGF G TC C F+G R P+ +
Sbjct: 583 LPCYCKN----GASCSPDDGICECAPGFRGTTCQRICSPGFYGH-----RCSQTCPQCVH 633
Query: 1141 TP-QCDQSTGQCVCVEGVEGPRCDK-CTRGYSG 1171
+ C TG C C+ G G C++ C G G
Sbjct: 634 SSGPCHHITGLCDCLPGFTGALCNEVCPSGRFG 666
Score = 142 bits (359), Expect = 2e-33
Identities = 128/436 (29%), Positives = 171/436 (39%), Gaps = 95/436 (21%)
Query: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGCKPCECHLQGS 828
G+ C +VC P G C C+ G C+ RC GT+GFG + C+C G+
Sbjct: 449 GINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCN--LTCQCLNGGA 506
Query: 829 VNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQ 887
CN + G C C G +C+ C G +G + C C+ HAD C P TG C C
Sbjct: 507 ----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCS-HADGCHPTTGHC-RCL 560
Query: 888 DYTMGHNCER-CLAGYYGDPIIGSGDHCR-PCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
G +C+ C G +G +C PC C +G SC D C
Sbjct: 561 PGWSGVHCDSVCAEGRWGP-------NCSLPCYCKNGA--------SCSPDDGI----CE 601
Query: 946 CDPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
C PG+ G+ C C+ G++G+ +C C + ++ P C TG C CL
Sbjct: 602 CAPGFRGTTCQRICSPGFYGH--RCSQTCPQC-----VHSSGP--CHHITGLC-DCLPGF 651
Query: 1005 EGEHC-QFCRFGYYGDALQQDCRK-CVCNYLGT---VQEHCN------GSDCQ------- 1046
G C + C G +G ++C C C GT + C GSDC
Sbjct: 652 TGALCNEVCPSGRFG----KNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAH 707
Query: 1047 ----------------CDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDP-CNCNAA 1089
C G+C C P G C + P + G C C C
Sbjct: 708 WGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFY---GKDCALICQCQN- 763
Query: 1090 HSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECR-ACDCDPRGIETPQCDQST 1148
G C+ +GQC C GF GR C Q+ G CR CDC + CD T
Sbjct: 764 ---GADCDHISGQCTCRTGFMGRHCE--QKCPSGTYGYGCRQICDC----LNNSTCDHIT 814
Query: 1149 GQCVCVEGVEGPRCDK 1164
G C C G +G RCD+
Sbjct: 815 GTCYCSPGWKGARCDQ 830
Score = 136 bits (342), Expect = 2e-31
Identities = 115/395 (29%), Positives = 153/395 (38%), Gaps = 94/395 (23%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCEC-HLQGS 828
L C+C G+ C+ G C C P G C C GT+G + + C+C H G
Sbjct: 497 LTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCA--ERCDCSHADG- 549
Query: 829 VNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQ-PCQCNGHADDCDPVTGECLNC 886
C+P TG C C G CD C G WG P+C PC C A C P G C C
Sbjct: 550 ----CHPTTGHCRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCKNGAS-CSPDDGIC-EC 602
Query: 887 QDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
G C+R C G+YG C C GP C+ + C
Sbjct: 603 APGFRGTTCQRICSPGFYGHRC---SQTCPQCVHSSGP---------CHH----ITGLCD 646
Query: 946 CDPGYIGSRCDD-CASGYFGN------------------------PSEVGGSC-QPC--- 976
C PG+ G+ C++ C SG FG P +G C QPC
Sbjct: 647 CLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPA 706
Query: 977 ----QCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC-QFCRFGYYGDALQQDCRK-CVC 1030
C + + + C G C KC G +C Q C G+YG +DC C C
Sbjct: 707 HWGPNCIHTCNCHNGAFCSAYDGEC-KCTPGWTGLYCTQRCPLGFYG----KDCALICQC 761
Query: 1031 NYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCD-RCAPNTWQLASGTGCDPCNCNAA 1089
NG+DC D +GQC C +G++C+ +C T+ CD N
Sbjct: 762 Q---------NGADC--DHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLN---- 806
Query: 1090 HSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD 1124
+C+ TG C C PG+ G C + + G+
Sbjct: 807 ---NSTCDHITGTCYCSPGWKGARCDQAGVIIVGN 838
Score = 78.6 bits (192), Expect = 5e-14
Identities = 81/316 (25%), Positives = 105/316 (33%), Gaps = 102/316 (32%)
Query: 274 YGHASECAPVDGFNEEVE--------GMVHGHCM------CRHNTKGLNCELCMDFYHDL 319
Y S+C P GF E E VHG C+ C G NC D H
Sbjct: 88 YRRKSQCCP--GFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDH-- 143
Query: 320 PWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD-CQHNTMGRNCEQCK 378
W P + +C C ++ A + A G G C+D C+ T G +C Q
Sbjct: 144 -WGP------HCTSRCQCKNGALCNPITGACHCAAG-FRGWRCEDRCEQGTYGNDCHQ-- 193
Query: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHC- 437
RC C QN CD T G+CRC G C
Sbjct: 194 ------------------RCQC-----QNGATCDHVT--------GECRCPPGYTGAFCE 222
Query: 438 DVCKEGFYDLSSEDPFGCK------------SCACNPLGTIPG----------------- 468
D+C G + E C+ SC +GT+ G
Sbjct: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQ 282
Query: 469 ---GNPCDSETGHCYCKRLVTGQHC-DQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFA 524
G CD+ TG C+C TG+ C D+C +G+ C C GG C+
Sbjct: 283 CHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVL----CAETCQCVNGG----KCYH 334
Query: 525 ESGQCSCRPHMIGRQC 540
SG C C G +C
Sbjct: 335 VSGACLCEAGFAGERC 350
Score = 70.1 bits (170), Expect = 2e-11
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 84/301 (27%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE-LCMDFYHDLPWRPAEGRNS 329
C+C AS C+P DG C C +G C+ +C ++ R S
Sbjct: 585 CYCKNGAS-CSPDDGI-----------CECAPGFRGTTCQRICSPGFYG-------HRCS 625
Query: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD-CQHNTMGRNCE------------- 375
C +C S CH + +G +C++ C G+NC
Sbjct: 626 QTCPQCV--HSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNP 683
Query: 376 -----QCKPFYY-----QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQ 425
QC P + Q PN C C N C +Y G+
Sbjct: 684 IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNC-----HNGAFCSAYD--------GE 730
Query: 426 CRCKLNVEGEHCDV-CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRL 484
C+C G +C C GFY K CA + G CD +G C C+
Sbjct: 731 CKCTPGWTGLYCTQRCPLGFYG---------KDCAL--ICQCQNGADCDHISGQCTCRTG 779
Query: 485 VTGQHCDQ-CLPEHWGLSNDLDGCRP-CDCDLGGALNNS-CFAESGQCSCRPHMIGRQCN 541
G+HC+Q C +G GCR CDC LNNS C +G C C P G +C+
Sbjct: 780 FMGRHCEQKCPSGTYGY-----GCRQICDC-----LNNSTCDHITGTCYCSPGWKGARCD 829
Query: 542 E 542
+
Sbjct: 830 Q 830
Score = 63.9 bits (154), Expect = 1e-09
Identities = 78/297 (26%), Positives = 96/297 (32%), Gaps = 62/297 (20%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM--CRHNTKGLNCELCMDFYHDLPWRPAEGRN 328
C C A +C V G G C C T G+NC +D P +G
Sbjct: 413 CSCQNGA-DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG-- 469
Query: 329 SNACKKCNCNEHSISCH-------FDMAVYLATGNVSGGVCDD------CQHNTMGRNCE 375
+C C H + C + L ++GG C+ C G CE
Sbjct: 470 --SCT-CKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCE 526
Query: 376 -QCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEG 434
C+ Y N ERC C A C T G CRC G
Sbjct: 527 LPCQDGTY--------GLNCAERCDCSHADG-----CHPTT--------GHCRCLPGWSG 565
Query: 435 EHCD-VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ- 492
HCD VC EG + + P CK+ G C + G C C G C +
Sbjct: 566 VHCDSVCAEGRWGPNCSLPCYCKN-----------GASCSPDDGICECAPGFRGTTCQRI 614
Query: 493 CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYF 549
C P +G C C G C +G C C P G CNEV P F
Sbjct: 615 CSPGFYG-HRCSQTCPQCVHSSG-----PCHHITGLCDCLPGFTGALCNEVCPSGRF 665
Score = 61.2 bits (147), Expect = 9e-09
Identities = 77/305 (25%), Positives = 101/305 (33%), Gaps = 70/305 (22%)
Query: 263 YDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE-LCMDFYHDLPW 321
Y + C C HA C P G HC C G++C+ +C
Sbjct: 534 YGLNCAERCDC-SHADGCHPTTG-----------HCRCLPGWSGVHCDSVC--------- 572
Query: 322 RPAEGR-NSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQ-CKP 379
AEGR N C C ++ SC D G+C+ C G C++ C P
Sbjct: 573 --AEGRWGPNCSLPCYC-KNGASCSPD-----------DGICE-CAPGFRGTTCQRICSP 617
Query: 380 FYYQHPERDIRDPNFCERCTCDPAGSQN-EGICDSYTDFSTGLI-------------AGQ 425
+Y H R C +C + G+CD F+ L AG
Sbjct: 618 GFYGH-----RCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGI 672
Query: 426 CRCKLNVEGEHCD---VCKEGFYDLSSEDPFGCKSCACNPLGTIP--GGNPCDSETGHCY 480
C C N D C G+ P N + T G C + G C
Sbjct: 673 CTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECK 732
Query: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
C TG +C Q P + D C C G C SGQC+CR +GR C
Sbjct: 733 CTPGWTGLYCTQRCPLGF---YGKDCALICQCQNGA----DCDHISGQCTCRTGFMGRHC 785
Query: 541 NEVEP 545
+ P
Sbjct: 786 EQKCP 790
Score = 52.0 bits (123), Expect = 5e-06
Identities = 67/307 (21%), Positives = 95/307 (30%), Gaps = 88/307 (28%)
Query: 294 VHGHCMCRHNTKGLNCE-LCMDFYHDLPWRPAEGRNSNACK-KCNCNEHSISCHFDMAVY 351
V G C C G CE LC G++ C+ +C C + CH
Sbjct: 206 VTGECRCPPGYTGAFCEDLC-----------PPGKHGPQCEQRCPCQNGGV-CHHVTGEC 253
Query: 352 LATGNVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCE----RCTCDPAGS- 405
G VC C G+NC Q E + C+ +C C P +
Sbjct: 254 SCPSGWMGTVCGQPCPEGRFGKNCSQ---------ECQCHNGGTCDAATGQCHCSPGYTG 304
Query: 406 ---QNE------GI-----CDSYTDFSTGLIAGQCRCKLNVEGEHCD--VCKEGFYDLSS 449
Q+E G+ C ++G C C+ GE C+ +C EG Y +
Sbjct: 305 ERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKC 364
Query: 450 EDPFGCK------------SCACNP----------------------LGTIPGGNPCDSE 475
+ C CAC P + + G CDS
Sbjct: 365 DKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSV 424
Query: 476 TGHCYCKRLVTGQHCD-QCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
TG C C G C C +G++ C G + C G C+C+
Sbjct: 425 TGKCTCAPGFKGIDCSTPCPLGTYGIN--------CSSRCGCKNDAVCSPVDGSCTCKAG 476
Query: 535 MIGRQCN 541
G C+
Sbjct: 477 WHGVDCS 483
Score = 45.8 bits (107), Expect = 4e-04
Identities = 44/178 (24%), Positives = 66/178 (37%), Gaps = 38/178 (21%)
Query: 369 TMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRC 428
TM R QC P +Y+ E + P+ ++C G C + C+C
Sbjct: 86 TMYRRKSQCCPGFYESGEMCV--PHCADKCV--------HGRC---------IAPNTCQC 126
Query: 429 KLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQ 488
+ G +C +G + P C C G C+ TG C+C G
Sbjct: 127 EPGWGGTNCSSACDGDH----WGPHCTSRCQCK------NGALCNPITGACHCAAGFRGW 176
Query: 489 HC-DQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEP 545
C D+C +G ND + C C G +C +G+C C P G C ++ P
Sbjct: 177 RCEDRCEQGTYG--NDCH--QRCQCQNGA----TCDHVTGECRCPPGYTGAFCEDLCP 226
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 159 bits (403), Expect = 2e-38
Identities = 140/537 (26%), Positives = 225/537 (41%), Gaps = 99/537 (18%)
Query: 7 LAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTS-TCGLHKPEPYC 65
L + LC+ ++ +E + A C P + D+ KL TCG PE +C
Sbjct: 25 LVWGHYDLCKTQIYTEEGKVWDYMA---CQPESTDMTKYLKVKLDPPDITCG-DPPETFC 80
Query: 66 IVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVE-----N 120
+ + ++CN++ + P+ ++ F +WQS E
Sbjct: 81 AMGNP------YMCNNEC---DASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQ 131
Query: 121 VTIQLDLEAEFHFT-HLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASF----P 175
V I L T ++++TF++ RP M++E+S D+G+TW Y+Y+A DC +F
Sbjct: 132 VNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPK 191
Query: 176 GISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYS----PRIQNLLK-- 229
+ V +IIC YS +T ++I F+I+D ++ PR++N+
Sbjct: 192 SVKDLSQHTVLEIICTEEYST-GYTTNSKIIH------FEIKDRFAFFAGPRLRNMASLY 244
Query: 230 --------------ITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYG 275
+T+LRI+ ++ +G+ +D R Y+YA+ D+ VRG C C
Sbjct: 245 GQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNL 301
Query: 276 HASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAE-----GRNSN 330
HA+ C N ++ C C HNT G +C C Y PW P +N
Sbjct: 302 HATVCVYD---NSKLT------CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN 352
Query: 331 AC-------KKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQ 383
C C C HS C + ++ +C C+HNT G++CE C+ Y++
Sbjct: 353 TCIPSISSIGNCECFGHSNRCSY-------IDLLNTVICVSCKHNTRGQHCELCRLGYFR 405
Query: 384 HPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEG 443
+ + D N C C C+P GS ++ C+ +G C CK G CD C G
Sbjct: 406 NASAQLDDENVCIECYCNPLGSIHDR-CNG---------SGFCECKTGTTGPKCDECLPG 455
Query: 444 FYDLSSEDPFGCKSCAC-NPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWG 499
+ +GC+ C N L G C + C C TG C++ E G
Sbjct: 456 -----NSWHYGCQPNVCDNELLHCQNGGTCHNNV-RCLCPAAYTGILCEKLRCEEAG 506
Score = 89.0 bits (219), Expect = 4e-17
Identities = 64/213 (30%), Positives = 89/213 (41%), Gaps = 54/213 (25%)
Query: 941 QLACVCDPGYIGSRCDDCASGYFGNPSEVGG----------SCQP-------CQC--HNN 981
+L C C+ G C C Y G P G +C P C+C H+N
Sbjct: 312 KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSN 371
Query: 982 ----IDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQ-----DCRKCVCNY 1032
ID + T C+ C ++T G+HC+ CR GY+ +A Q C +C CN
Sbjct: 372 RCSYIDLLN-------TVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP 424
Query: 1033 LGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAP-NTWQLASGTGCDP--CNCNAA 1089
LG++ + CNGS G C C G CD C P N+W GC P C+
Sbjct: 425 LGSIHDRCNGS--------GFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCDNELL 472
Query: 1090 H-SFGPSCNEFTGQCQCMPGFGGRTCSE--CQE 1119
H G +C+ +C C + G C + C+E
Sbjct: 473 HCQNGGTCHN-NVRCLCPAAYTGILCEKLRCEE 504
Score = 64.7 bits (156), Expect = 8e-10
Identities = 52/167 (31%), Positives = 68/167 (40%), Gaps = 28/167 (16%)
Query: 773 CECDPQGSLSSVCDP-NGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG------CKPCECH 824
CEC + S D N C C+ N G+ C C G F + C C C+
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCN 423
Query: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECL 884
GS++ CN +G C C G +CD CLPG+ CQP C+ E L
Sbjct: 424 PLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD----------NELL 472
Query: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPD----GPDSGR 927
+CQ+ HN RCL P +G C C + G DSG+
Sbjct: 473 HCQNGGTCHNNVRCLC-----PAAYTGILCEKLRCEEAGSCGSDSGQ 514
Score = 62.8 bits (151), Expect = 3e-09
Identities = 63/251 (25%), Positives = 89/251 (35%), Gaps = 65/251 (25%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSGCKPCECHLQGSVN 830
C+C+ ++ V D + C+C N G C +C G + P P +G+ N
Sbjct: 297 CKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP---KGTAN 352
Query: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV----TGECLNC 886
C+P S C+C GH++ C + T C++C
Sbjct: 353 T----------------------CIP---SISSIGNCECFGHSNRCSYIDLLNTVICVSC 387
Query: 887 QDYTMGHNCERCLAGYYGDPIIGSGDH--CRPCPC-PDGPDSGRQFARSCYQDPVTLQLA 943
+ T G +CE C GY+ + D C C C P G D
Sbjct: 388 KHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLG----------SIHDRCNGSGF 437
Query: 944 CVCDPGYIGSRCDDCASG----YFGNPSEVGGSCQPCQ----CHNNIDTTDPEA-----C 990
C C G G +CD+C G Y P+ CQ CHNN+ P A C
Sbjct: 438 CECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILC 497
Query: 991 DK----ETGRC 997
+K E G C
Sbjct: 498 EKLRCEEAGSC 508
Score = 51.6 bits (122), Expect = 7e-06
Identities = 57/215 (26%), Positives = 82/215 (38%), Gaps = 26/215 (12%)
Query: 867 CQCNGHADDC--DPVTGECLNCQDYTMGHNCERCLAGYYGDPII---------GSGDHCR 915
C+CN HA C D C C+ T G +C +C Y G P G+ + C
Sbjct: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 916 PCPCPDGPDSGRQFARSC-YQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ 974
P G + C Y D + + C G C+ C GYF N S
Sbjct: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
Query: 975 PC-QCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYL 1033
C +C+ N + + C+ +G C +C T G C C G++ C+ VC+
Sbjct: 416 VCIECYCNPLGSIHDRCN-GSGFC-ECKTGTTGPKCDEC---LPGNSWHYGCQPNVCD-- 468
Query: 1034 GTVQEHC-NGSDCQCDKATGQCLCLPNVIGQNCDR 1067
HC NG C + +CLC G C++
Sbjct: 469 -NELLHCQNGGTCHNNV---RCLCPAAYTGILCEK 499
Score = 50.4 bits (119), Expect = 2e-05
Identities = 47/176 (26%), Positives = 62/176 (35%), Gaps = 46/176 (26%)
Query: 1027 KCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN----TWQLASGTGCD 1082
+C CN TV C D + C C N G +C +C N W S
Sbjct: 296 RCKCNLHATV--------CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL--- 344
Query: 1083 PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRT----------CSECQELFWG--------- 1123
P A++ PS + G C+C G R C C+ G
Sbjct: 345 PIPKGTANTCIPSISSI-GNCECF-GHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLG 402
Query: 1124 ---------DPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYS 1170
D + C C C+P G +C+ S G C C G GP+CD+C G S
Sbjct: 403 YFRNASAQLDDENVCIECYCNPLGSIHDRCNGS-GFCECKTGTTGPKCDECLPGNS 457
Score = 49.7 bits (117), Expect = 3e-05
Identities = 40/146 (27%), Positives = 56/146 (38%), Gaps = 30/146 (20%)
Query: 426 CRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYC---- 481
C C+ N G C CK+ + P+ S P GT P S G+C C
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGR----PWSPGSYLPIPKGTANTCIPSISSIGNCECFGHS 370
Query: 482 -----------------KRLVTGQHCDQCLPEHW-GLSNDLDG---CRPCDCDLGGALNN 520
K GQHC+ C ++ S LD C C C+ G++++
Sbjct: 371 NRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD 430
Query: 521 SCFAESGQCSCRPHMIGRQCNEVEPG 546
C SG C C+ G +C+E PG
Sbjct: 431 RCNG-SGFCECKTGTTGPKCDECLPG 455
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 17/113 (15%)
Query: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
+ C C+P GS+ C+ G C+C+ G C+ C PG GC+P C +
Sbjct: 418 IECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWH--YGCQPNVCDNE---- 470
Query: 831 AFCNPVTGQCHCFQGVYARQCDRCL-PGHWGFPSCQPCQCNGHADDCDPVTGE 882
HC G RCL P + C+ +C A C +G+
Sbjct: 471 --------LLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCE-EAGSCGSDSGQ 514
Score = 31.2 bits (69), Expect = 9.4
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 6/54 (11%)
Query: 1121 FWGDPDVECRA-CDCDPRGIETPQC--DQSTGQCVCVEGVEGPRCDKCTRGYSG 1171
F+ D++ R C C+ + C D S C C GP C KC + Y G
Sbjct: 285 FYAISDIKVRGRCKCN---LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 152 bits (385), Expect = 2e-36
Identities = 79/213 (37%), Positives = 104/213 (48%), Gaps = 14/213 (6%)
Query: 839 QCHCFQGVYARQCDRC------LPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMG 892
+C C G C+ C +PG +C C CNGHA CDPV G CLNCQ T G
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIG 952
C +C AG++GD + + CRPCPCP D+ R+F+ +C+ D C PGY G
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCP-YIDASRRFSDTCFLDTDGQATCDACAPGYTG 848
Query: 953 SRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
RC+ CA GY GNP + GG C+P + I D +G +C + G C C
Sbjct: 849 RRCESCAPGYEGNPIQPGGKCRP--VNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNEC 906
Query: 1013 RFGYYGDALQ--QDCRKCVCNYLGTVQEHCNGS 1043
G + + + C KC C +G V HC S
Sbjct: 907 ADGSFHLSTRNPDGCLKCFC--MG-VSRHCTSS 936
Score = 141 bits (355), Expect = 6e-33
Identities = 156/609 (25%), Positives = 213/609 (34%), Gaps = 103/609 (16%)
Query: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
C C +G +C+ C Y P G C++C+C+ HS +C +
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTP----SGLYLGTCERCSCHGHSEACEPET--------- 1172
Query: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC--DPAGSQNEGICDSYT 415
G C CQH+T G CEQC+P YY +R P C+ C C DPA Q C T
Sbjct: 1173 --GACQGCQHHTEGPRCEQCQPGYYGDAQRGT--PQDCQLCPCYGDPAAGQAAHTCFLDT 1228
Query: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSED-----------PFGCKSCACNPLG 464
D A C G HC+ C G+Y S+ P GC C+P G
Sbjct: 1229 DGHPTCDA----CSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCN---CDPQG 1281
Query: 465 TIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFA 524
++ + CD+ G C CK V G C C P H+ L P C L C
Sbjct: 1282 SV--SSQCDA-AGQCQCKAQVEGLTCSHCRPHHF----HLSASNPDGC-----LPCFCMG 1329
Query: 525 ESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWT 584
+ QC+ + PG + G ++V Q R T
Sbjct: 1330 ITQQCASSAYTRHLISTHFAPGDF-----------------QGFALVNPQ----RNSRLT 1368
Query: 585 GAGFVR-VPEGAYLEF----------FIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQR 633
G V VPEGA L F F +P + + D + Y +L
Sbjct: 1369 GEFTVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGS 1428
Query: 634 PGRIPTSSRCGNTIPDDDNQVVSLSPGSR-YVVLPRPVCFEKGTNYTVRLELPQYTSSDS 692
P P GN I +Q P R Y ++ R + + E +D
Sbjct: 1429 PLSDPDVQITGNNIMLVASQPALQGPERRSYEIMFREEFWRRPDGQPATREHLLMALADL 1488
Query: 693 DVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMT 752
D S+ P S+ ++ + G + RC +
Sbjct: 1489 DELLIRATFSSV---PLAASISAVSLEVAQPGPSNRPRALEVEECRC---PPGYIGLSCQ 1542
Query: 753 DVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTF 811
D + S L CEC+ S +C P G C QC+ N G C CAPG +
Sbjct: 1543 DCAPGYTRTGSGLYLGHCELCECNGH---SDLCHPETGACSQCQHNAAGEFCELCAPGYY 1599
Query: 812 GFG----PSGCKPCECHLQGSVNAFCNPVTG------QC-HCFQGVYARQCDRCLPGHWG 860
G P C+PC C L N F +C C G + C++C PG+ G
Sbjct: 1600 GDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVG 1659
Query: 861 FPSCQPCQC 869
PS Q QC
Sbjct: 1660 NPSVQGGQC 1668
Score = 133 bits (334), Expect = 2e-30
Identities = 77/215 (35%), Positives = 103/215 (47%), Gaps = 21/215 (9%)
Query: 839 QCHCFQGVYARQCDRCLPGHWGFPS------CQPCQCNGHADDCDPVTGECLNCQDYTMG 892
QC C G C C G+ PS C+ C C+GH++ C+P TG C CQ +T G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIG 952
CE+C GYYGD G+ C+ CPC P +G Q A +C+ D C PG+ G
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAG-QAAHTCFLDTDGHPTCDACSPGHSG 1243
Query: 953 SRCDDCASGYFGNPSEVGGSCQ-------PCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
C+ CA GY+GNPS+ G CQ P C+ + + CD G+C +C E
Sbjct: 1244 RHCERCAPGYYGNPSQ-GQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQC-QCKAQVE 1300
Query: 1006 GEHCQFCR-FGYYGDALQQD-CRKCVCNYLGTVQE 1038
G C CR ++ A D C C C +G Q+
Sbjct: 1301 GLTCSHCRPHHFHLSASNPDGCLPCFC--MGITQQ 1333
Score = 130 bits (327), Expect = 1e-29
Identities = 84/231 (36%), Positives = 106/231 (45%), Gaps = 28/231 (12%)
Query: 935 QDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVG-GSCQPCQCHNNIDTTDPEACDKE 993
QDP C C PGY G C DC +GY PS + G+C+ C CH + EAC+ E
Sbjct: 1117 QDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGH-----SEACEPE 1171
Query: 994 TGRCLKCLYHTEGEHCQFCRFGYYGDALQ---QDCRKCVCNYLGTVQEHCNGSDCQCDKA 1050
TG C C +HTEG C+ C+ GYYGDA + QDC+ C C + + D
Sbjct: 1172 TGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGH 1231
Query: 1051 TGQCLCLPNVIGQNCDRCAPNTW-QLASGTGCD---------PCNCNAAHSFGPSCNEFT 1100
C P G++C+RCAP + + G C CNC+ S C +
Sbjct: 1232 PTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAA 1290
Query: 1101 GQCQCMPGFGGRTCSECQ----ELFWGDPDVECRACDCDPRGIETPQCDQS 1147
GQCQC G TCS C+ L +PD C C C GI T QC S
Sbjct: 1291 GQCQCKAQVEGLTCSHCRPHHFHLSASNPD-GCLPCFC--MGI-TQQCASS 1337
Score = 125 bits (313), Expect = 5e-28
Identities = 58/144 (40%), Positives = 72/144 (50%), Gaps = 9/144 (6%)
Query: 839 QCHCFQGVYARQCDRCLPGHWGFPS------CQPCQCNGHADDCDPVTGECLNCQDYTMG 892
+C C G C C PG+ S C+ C+CNGH+D C P TG C CQ G
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1588
Query: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCP-DGPDSGRQFARSCYQDPVTLQLACVCDPGYI 951
CE C GYYGD G+ + C+PC CP P++ F+R+C C+PGY
Sbjct: 1589 EFCELCAPGYYGDATAGTPEDCQPCACPLTNPEN--MFSRTCESLGAGGYRCTACEPGYT 1646
Query: 952 GSRCDDCASGYFGNPSEVGGSCQP 975
G C+ C GY GNPS GG C P
Sbjct: 1647 GQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 97.8 bits (242), Expect = 8e-20
Identities = 62/196 (31%), Positives = 85/196 (43%), Gaps = 33/196 (16%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSN 330
C C+GH+ C P G + C+H+T+G CE C Y+ A+
Sbjct: 1159 CSCHGHSEACEPETGACQG----------CQHHTEGPRCEQCQPGYYG----DAQRGTPQ 1204
Query: 331 ACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHP----- 385
C+ C C + +L T CD C GR+CE+C P YY +P
Sbjct: 1205 DCQLCPCYGDPAAGQAAHTCFLDTDGHP--TCDACSPGHSGRHCERCAPGYYGNPSQGQP 1262
Query: 386 -ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
+RD + P C CDP GS + CD+ AGQC+CK VEG C C+
Sbjct: 1263 CQRDSQVPGPIG-CNCDPQGSVSSQ-CDA---------AGQCQCKAQVEGLTCSHCRPHH 1311
Query: 445 YDLSSEDPFGCKSCAC 460
+ LS+ +P GC C C
Sbjct: 1312 FHLSASNPDGCLPCFC 1327
Score = 96.7 bits (239), Expect = 2e-19
Identities = 65/197 (32%), Positives = 82/197 (41%), Gaps = 41/197 (20%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCM-DFYHDLPWRPAEGRN 328
C C GHAS C PV +GHC+ C+HNT+G C C F+ D A
Sbjct: 764 CNCNGHASSCDPV-----------YGHCLNCQHNTEGPQCNKCKAGFFGD-----AMKAT 807
Query: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
+ +C+ C C S F +L T + CD C GR CE C P Y +P
Sbjct: 808 ATSCRPCPCPYIDASRRFSDTCFLDTDGQA--TCDACAPGYTGRRCESCAPGYEGNP--- 862
Query: 389 IRDPNFC-----ERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEG 443
I+ C E CD GS G CRCK NV G C+ C +G
Sbjct: 863 IQPGGKCRPVNQEIVRCDERGSM-------------GTSGEACRCKNNVVGRLCNECADG 909
Query: 444 FYDLSSEDPFGCKSCAC 460
+ LS+ +P GC C C
Sbjct: 910 SFHLSTRNPDGCLKCFC 926
Score = 94.7 bits (234), Expect = 7e-19
Identities = 52/133 (39%), Positives = 68/133 (51%), Gaps = 13/133 (9%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPSEVG-GSCQPCQCHNNIDTTDPEACDKETGRCLKCLY 1002
C C PGYIG C DCA GY S + G C+ C+C+ + D C ETG C +C +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL-----CHPETGACSQCQH 1584
Query: 1003 HTEGEHCQFCRFGYYGDA---LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATG-QC-LCL 1057
+ GE C+ C GYYGDA +DC+ C C T E+ C+ A G +C C
Sbjct: 1585 NAAGEFCELCAPGYYGDATAGTPEDCQPCACPL--TNPENMFSRTCESLGAGGYRCTACE 1642
Query: 1058 PNVIGQNCDRCAP 1070
P GQ C++C P
Sbjct: 1643 PGYTGQYCEQCGP 1655
Score = 88.2 bits (217), Expect = 7e-17
Identities = 67/229 (29%), Positives = 93/229 (40%), Gaps = 60/229 (26%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFGFGPSG-----CKPCECHLQGSVNAFCNPVTGQCH-CFQ 844
QC C P G +C C G + PSG C+ C CH C P TG C C
Sbjct: 1125 QCSCPPGYRGPSCQDCDTG-YTRTPSGLYLGTCERCSCHGHSEA---CEPETGACQGCQH 1180
Query: 845 GVYARQCDRCLPGHWGF------PSCQPCQCNGHADDCDPVTGE--------------CL 884
+C++C PG++G CQ C C G DP G+ C
Sbjct: 1181 HTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG-----DPAAGQAAHTCFLDTDGHPTCD 1235
Query: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
C G +CERC GYYG+P G C+ GP + C
Sbjct: 1236 ACSPGHSGRHCERCAPGYYGNP--SQGQPCQRDSQVPGP------------------IGC 1275
Query: 945 VCDP-GYIGSRCDDCASGYFGNPSEVGG-SCQPCQCHN-NIDTTDPEAC 990
CDP G + S+CD A+G ++V G +C C+ H+ ++ ++P+ C
Sbjct: 1276 NCDPQGSVSSQCD--AAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGC 1322
Score = 80.9 bits (198), Expect = 1e-14
Identities = 66/207 (31%), Positives = 86/207 (41%), Gaps = 35/207 (16%)
Query: 1005 EGEHCQFCRFGYYGDALQQDC-----RKCVCNYLGTVQE-HCNGSDCQCDKATGQCL-CL 1057
E E C C GY G + Q DC R YLGT + C+G C+ TG C C
Sbjct: 1122 EVEQCS-CPPGYRGPSCQ-DCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQ 1179
Query: 1058 PNVIGQNCDRCAPNTW---QLASGTGCDPCNC-------NAAHSFGPSCNEFTGQCQCMP 1107
+ G C++C P + Q + C C C AAH+ + C P
Sbjct: 1180 HHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSP 1239
Query: 1108 GFGGRTCSECQELFWGDPDV--ECR---------ACDCDPRGIETPQCDQSTGQCVCVEG 1156
G GR C C ++G+P C+ C+CDP+G + QCD + GQC C
Sbjct: 1240 GHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKAQ 1298
Query: 1157 VEGPRCDKCTRGY---SGVFPD-CTPC 1179
VEG C C + S PD C PC
Sbjct: 1299 VEGLTCSHCRPHHFHLSASNPDGCLPC 1325
Score = 76.3 bits (186), Expect = 3e-13
Identities = 45/146 (30%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 791 QCQCRPNVVGRTCNRCAPGTFGFGP----SGCKPCECHLQGSVNAFCNPVTGQC-HCFQG 845
+C+C P +G +C CAPG G C+ CEC+ + C+P TG C C
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL---CHPETGACSQCQHN 1585
Query: 846 VYARQCDRCLPGHWGFPS------CQPCQC------NGHADDCDPVTG---ECLNCQDYT 890
C+ C PG++G + CQPC C N + C+ + C C+
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 891 MGHNCERCLAGYYGDPIIGSGDHCRP 916
G CE+C GY G+P + G C P
Sbjct: 1646 TGQYCEQCGPGYVGNPSV-QGGQCLP 1670
Score = 74.3 bits (181), Expect = 1e-12
Identities = 65/208 (31%), Positives = 84/208 (40%), Gaps = 38/208 (18%)
Query: 1007 EHCQFCRFGYYGDALQQDCRKCVCN--------YLGTVQE-HCNGSDCQCDKATGQCL-C 1056
E C+ C GY G C C + YLGT +CNG CD G CL C
Sbjct: 729 EECR-CPIGYSG----LSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNC 783
Query: 1057 LPNVIGQNCDRCAPNTW---QLASGTGCDPCNC---NAAHSFGPSCNEFT-GQCQC---M 1106
N G C++C + A+ T C PC C +A+ F +C T GQ C
Sbjct: 784 QHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACA 843
Query: 1107 PGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQ------STGQCVCVEGVEGP 1160
PG+ GR C C + G+P C P E +CD+ S C C V G
Sbjct: 844 PGYTGRRCESCAPGYEGNPIQP--GGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGR 901
Query: 1161 RCDKCTRG---YSGVFPDCTPCHQCFAL 1185
C++C G S PD C +CF +
Sbjct: 902 LCNECADGSFHLSTRNPD--GCLKCFCM 927
Score = 73.6 bits (179), Expect = 2e-12
Identities = 52/201 (25%), Positives = 78/201 (38%), Gaps = 63/201 (31%)
Query: 944 CVCDPGYIGSRCDDCASGYFGNPS-EVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLY 1002
C C GY G C+ C + + P G+C C C+ + + CD G CL C +
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASS-----CDPVYGHCLNCQH 785
Query: 1003 HTEGEHCQFCRFGYYGDALQQ---DCRKCVCNYL-------------------------G 1034
+TEG C C+ G++GDA++ CR C C Y+ G
Sbjct: 786 NTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPG 845
Query: 1035 TVQEHCN-------------GSDCQ--------CDK-----ATGQ-CLCLPNVIGQNCDR 1067
C G C+ CD+ +G+ C C NV+G+ C+
Sbjct: 846 YTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNE 905
Query: 1068 CAPNTWQLASGT--GCDPCNC 1086
CA ++ L++ GC C C
Sbjct: 906 CADGSFHLSTRNPDGCLKCFC 926
Score = 65.5 bits (158), Expect = 5e-10
Identities = 44/141 (31%), Positives = 59/141 (41%), Gaps = 27/141 (19%)
Query: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGT---GCDPCNCNAAHSFGPSCNEFTGQC-QCMPG 1108
+C C P IG +C CAP + SG C+ C CN HS C+ TG C QC
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN-GHS--DLCHPETGACSQCQHN 1585
Query: 1109 FGGRTCSECQELFWGDPDV----ECRACDC---DPRGIETPQCDQSTGQCVCVEGVEGPR 1161
G C C ++GD +C+ C C +P + + C+ G G R
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL--------GAGGYR 1637
Query: 1162 CDKCTRGYSGVFPDCTPCHQC 1182
C C GY+G + C QC
Sbjct: 1638 CTACEPGYTGQY-----CEQC 1653
Score = 64.7 bits (156), Expect = 8e-10
Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 365 CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAG 424
C G +CE C + + P C C C+ S CD + G
Sbjct: 733 CPIGYSGLSCESCDAHFTRVPGGPYLGT--CSGCNCNGHASS----CDP--------VYG 778
Query: 425 QC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKSCACNPLGTIPG-GNPCDSET-GHCY 480
C C+ N EG C+ CK GF+ D C+ C C + + C +T G
Sbjct: 779 HCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 838
Query: 481 CKRLV---TGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQ-CSCRPHM 535
C TG+ C+ C P + G G CRP + ++ SG+ C C+ ++
Sbjct: 839 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 898
Query: 536 IGRQCNEVEPGYY 548
+GR CNE G +
Sbjct: 899 VGRLCNECADGSF 911
Score = 62.8 bits (151), Expect = 3e-09
Identities = 41/147 (27%), Positives = 54/147 (36%), Gaps = 24/147 (16%)
Query: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQ-CMPGFGG 1111
QC C P G +C C + SG C + H +C TG CQ C G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 1112 RTCSECQELFWGDPD----VECRACDC--DPRGIET-----------PQCDQSTGQCVCV 1154
C +CQ ++GD +C+ C C DP + P CD C
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCD------ACS 1238
Query: 1155 EGVEGPRCDKCTRGYSGVFPDCTPCHQ 1181
G G C++C GY G PC +
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQR 1265
Score = 62.4 bits (150), Expect = 4e-09
Identities = 51/166 (30%), Positives = 66/166 (39%), Gaps = 27/166 (16%)
Query: 402 PAGSQNEGIC-DSYTDFSTG----LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-C 455
PA S+ GI D TG L QC C G C C G+ S G C
Sbjct: 1097 PAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTC 1156
Query: 456 KSCACNPLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDL 514
+ C+C+ C+ ETG C C+ G C+QC P ++G D P DC L
Sbjct: 1157 ERCSCHG-----HSEACEPETGACQGCQHHTEGPRCEQCQPGYYG---DAQRGTPQDCQL 1208
Query: 515 --------GGALNNSCFAESG---QC-SCRPHMIGRQCNEVEPGYY 548
G ++CF ++ C +C P GR C PGYY
Sbjct: 1209 CPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYY 1254
Score = 62.4 bits (150), Expect = 4e-09
Identities = 36/100 (36%), Positives = 44/100 (44%), Gaps = 19/100 (19%)
Query: 794 CRPNVVGRTCNRCAPGTFGFGPSGCKPCE------------CHLQGSVNAFCNPVTGQCH 841
C P GR C RCAPG +G PS +PC+ C QGSV++ C+ GQC
Sbjct: 1237 CSPGHSGRHCERCAPGYYG-NPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQ 1294
Query: 842 CFQGVYARQCDRCLPGHWGFPS-----CQPCQCNGHADDC 876
C V C C P H+ + C PC C G C
Sbjct: 1295 CKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQC 1334
Score = 59.3 bits (142), Expect = 3e-08
Identities = 47/145 (32%), Positives = 63/145 (43%), Gaps = 19/145 (13%)
Query: 1005 EGEHCQFCRFGYYGDALQQDCRKCVCN-----YLGTVQE-HCNGSDCQCDKATGQCL-CL 1057
E E C+ C GY G + Q DC YLG + CNG C TG C C
Sbjct: 1526 EVEECR-CPPGYIGLSCQ-DCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQ 1583
Query: 1058 PNVIGQNCDRCAPNTW-QLASGT--GCDPCNC---NAAHSFGPSCNEFTG---QCQ-CMP 1107
N G+ C+ CAP + +GT C PC C N + F +C +C C P
Sbjct: 1584 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 1108 GFGGRTCSECQELFWGDPDVECRAC 1132
G+ G+ C +C + G+P V+ C
Sbjct: 1644 GYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 55.1 bits (131), Expect = 6e-07
Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 1102 QCQCMPGFGGRTCSECQELFWGDPDV----ECRACDCDPRGIETPQCDQSTGQCV-CVEG 1156
QC C PG+ G +C +C + P C C C + C+ TG C C
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGH---SEACEPETGACQGCQHH 1181
Query: 1157 VEGPRCDKCTRGYSGVFPDCTP--CHQC 1182
EGPRC++C GY G TP C C
Sbjct: 1182 TEGPRCEQCQPGYYGDAQRGTPQDCQLC 1209
Score = 55.1 bits (131), Expect = 6e-07
Identities = 42/146 (28%), Positives = 57/146 (39%), Gaps = 22/146 (15%)
Query: 882 ECLNCQDYTMGHNCERCLAGYYGDPIIGSG---DHCRPCPCPDGPDSGRQFARSCYQDPV 938
EC C +G +C+ C GY GSG HC C C D +C Q
Sbjct: 1529 EC-RCPPGYIGLSCQDCAPGYTRT---GSGLYLGHCELCECNGHSDLCHPETGACSQ--- 1581
Query: 939 TLQLACVCDPGYIGSRCDDCASGYFGNPSE-VGGSCQPCQCH----NNIDTTDPEACDKE 993
C G C+ CA GY+G+ + CQPC C N+ + E+
Sbjct: 1582 -------CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAG 1634
Query: 994 TGRCLKCLYHTEGEHCQFCRFGYYGD 1019
RC C G++C+ C GY G+
Sbjct: 1635 GYRCTACEPGYTGQYCEQCGPGYVGN 1660
Score = 50.1 bits (118), Expect = 2e-05
Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 7/52 (13%)
Query: 775 CDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCKPCEC 823
CD +GS+ + +G C+C+ NVVGR CN CA G+F P GC C C
Sbjct: 879 CDERGSMGT----SGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 47.8 bits (112), Expect = 1e-04
Identities = 36/121 (29%), Positives = 45/121 (37%), Gaps = 28/121 (23%)
Query: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSN 330
C C GH+ C P G + C+HN G CELC Y+ A
Sbjct: 1563 CECNGHSDLCHPETGACSQ----------CQHNAAGEFCELCAPGYYG----DATAGTPE 1608
Query: 331 ACKKCNC------NEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQH 384
C+ C C N S +C L G G C C+ G+ CEQC P Y +
Sbjct: 1609 DCQPCACPLTNPENMFSRTCES-----LGAG---GYRCTACEPGYTGQYCEQCGPGYVGN 1660
Query: 385 P 385
P
Sbjct: 1661 P 1661
Score = 43.1 bits (100), Expect = 0.002
Identities = 35/118 (29%), Positives = 45/118 (38%), Gaps = 27/118 (22%)
Query: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSG-CKP-----CECH 824
C D G + CD C P GR C CAPG G P G C+P C
Sbjct: 829 CFLDTDGQ--ATCDA------CAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCD 880
Query: 825 LQGSVNAFCNPVTGQ-CHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCNGHADDC 876
+GS+ +G+ C C V R C+ C G + + C C C G + C
Sbjct: 881 ERGSMG-----TSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHC 933
Score = 35.0 bits (79), Expect = 0.65
Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 16/89 (17%)
Query: 1000 CLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC-NGSDCQCDKATGQCLCLP 1058
C+ E E CR G+ GD + + C ++E C +G CQ + CLCLP
Sbjct: 4119 CMPAGEYEFQCLCRDGFKGDLCEHEENPC------QLREPCLHGGTCQGTR----CLCLP 4168
Query: 1059 NVIGQNCDR-----CAPNTWQLASGTGCD 1082
G C + A + W L G D
Sbjct: 4169 GFSGPRCQQGSGHGIAESDWHLEGSGGND 4197
Score = 32.0 bits (71), Expect = 5.5
Identities = 23/90 (25%), Positives = 30/90 (33%), Gaps = 24/90 (26%)
Query: 914 CRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSC 973
CR PC +G C+ D + CVC G+ GSRC+
Sbjct: 3848 CRDRPCQNGGQ--------CH-DSESSSYVCVCPAGFTGSRCE---------------HS 3883
Query: 974 QPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Q CH D ++ GR C H
Sbjct: 3884 QALHCHPEACGPDATCVNRPDGRGYTCRCH 3913
Score = 31.6 bits (70), Expect = 7.2
Identities = 22/91 (24%), Positives = 33/91 (36%), Gaps = 14/91 (15%)
Query: 1074 QLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACD 1133
Q + C+ C + P+ E+ QC C GF G C E C
Sbjct: 4101 QCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGFKGDLCEH-----------EENPCQ 4148
Query: 1134 CDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
+ C + +C+C+ G GPRC +
Sbjct: 4149 LREPCLHGGTCQGT--RCLCLPGFSGPRCQQ 4177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,118,163
Number of Sequences: 37866
Number of extensions: 4005873
Number of successful extensions: 26501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 1134
Number of HSP's that attempted gapping in prelim test: 12725
Number of HSP's gapped (non-prelim): 6855
length of query: 1786
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1669
effective length of database: 13,817,196
effective search space: 23060900124
effective search space used: 23060900124
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.