Guide to the Human Genome
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Search of human proteins with 167614502

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|167614502 protein phosphatase 1, regulatory (inhibitor)
subunit 3A [Homo sapiens]
         (1122 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|167614502 protein phosphatase 1, regulatory (inhibitor) subun...  2261   0.0  
gi|4885559 protein phosphatase 1, regulatory (inhibitor) subunit...    93   2e-18
gi|5453948 protein phosphatase 1, regulatory subunit 3D [Homo sa...    84   7e-16
gi|153792466 protein phosphatase 1, regulatory (inhibitor) subun...    82   3e-15
gi|239757810 PREDICTED: similar to protein phosphatase 1, regula...    80   1e-14
gi|58761532 protein phosphatase 1, regulatory (inhibitor) subuni...    80   1e-14
gi|223278393 protein phosphatase 1, regulatory (inhibitor) subun...    63   2e-09
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    41   0.007
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    41   0.007
gi|87299628 biorientation of chromosomes in cell division 1-like...    39   0.028
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    38   0.062
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       37   0.11 
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]       37   0.11 
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       37   0.11 
gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s...    37   0.14 
gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo s...    37   0.14 
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    37   0.14 
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi...    36   0.23 
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi...    36   0.23 
gi|41393608 reticulon 3 isoform b [Homo sapiens]                       36   0.23 
gi|50083281 KIAA1853 protein [Homo sapiens]                            36   0.23 
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi...    35   0.31 
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ...    35   0.52 
gi|39812492 TH1-like protein [Homo sapiens]                            34   0.68 
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         34   0.68 
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]          34   0.89 
gi|13376834 zinc finger and SCAN domain containing 16 [Homo sapi...    34   0.89 
gi|50962882 G patch domain containing 8 [Homo sapiens]                 34   0.89 
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             34   0.89 
gi|123173752 synaptotagmin XIV-like [Homo sapiens]                     33   1.2  

>gi|167614502 protein phosphatase 1, regulatory (inhibitor) subunit 3A
            [Homo sapiens]
          Length = 1122

 Score = 2261 bits (5859), Expect = 0.0
 Identities = 1122/1122 (100%), Positives = 1122/1122 (100%)

Query: 1    MEPSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDIYLDTPSSG 60
            MEPSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDIYLDTPSSG
Sbjct: 1    MEPSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDIYLDTPSSG 60

Query: 61   TRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHTEEYVLAPLFDLPSSKEDLM 120
            TRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHTEEYVLAPLFDLPSSKEDLM
Sbjct: 61   TRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHTEEYVLAPLFDLPSSKEDLM 120

Query: 121  QQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNS 180
            QQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNS
Sbjct: 121  QQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNS 180

Query: 181  CDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEP 240
            CDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEP
Sbjct: 181  CDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEP 240

Query: 241  VKPWKEVPNRQIKGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEAS 300
            VKPWKEVPNRQIKGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEAS
Sbjct: 241  VKPWKEVPNRQIKGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEAS 300

Query: 301  NRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQ 360
            NRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQ
Sbjct: 301  NRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQ 360

Query: 361  IHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLG 420
            IHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLG
Sbjct: 361  IHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLG 420

Query: 421  DTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVK 480
            DTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVK
Sbjct: 421  DTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVK 480

Query: 481  DLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHD 540
            DLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHD
Sbjct: 481  DLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHD 540

Query: 541  QERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEH 600
            QERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEH
Sbjct: 541  QERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEH 600

Query: 601  HHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQSWNVLE 660
            HHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQSWNVLE
Sbjct: 601  HHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQSWNVLE 660

Query: 661  SQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHG 720
            SQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHG
Sbjct: 661  SQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHG 720

Query: 721  ITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRN 780
            ITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRN
Sbjct: 721  ITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRN 780

Query: 781  DDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTG 840
            DDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTG
Sbjct: 781  DDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTG 840

Query: 841  NITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHS 900
            NITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHS
Sbjct: 841  NITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHS 900

Query: 901  AFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREI 960
            AFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREI
Sbjct: 901  AFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREI 960

Query: 961  QGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLEN 1020
            QGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLEN
Sbjct: 961  QGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLEN 1020

Query: 1021 MEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKIPYFL 1080
            MEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKIPYFL
Sbjct: 1021 MEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKIPYFL 1080

Query: 1081 LFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK 1122
            LFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK
Sbjct: 1081 LFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK 1122


>gi|4885559 protein phosphatase 1, regulatory (inhibitor) subunit 3C
           [Homo sapiens]
          Length = 317

 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 62/178 (34%), Positives = 90/178 (50%), Gaps = 12/178 (6%)

Query: 62  RRVSFADSFGFNLVSVKEF-DCWELPSASTTFDL------GTDIFHTEEYVLAPLFDLPS 114
           +RV FADS G +L ++  F D  E P+    FDL       + + H EE  L  + D P 
Sbjct: 83  KRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSALKHHEEKNL--ILDFPQ 140

Query: 115 SKEDLMQ-QLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDIL 173
              D +  +   QK  +      L   ++ G ++V NVSFEK V +R++ D W+ + D+ 
Sbjct: 141 PSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVD 200

Query: 174 AEYVPNSCDG-ETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFI 230
             Y+ N   G ++D FSF I L PP      K+EFCI Y  +   FW NN+G NY  +
Sbjct: 201 CVYMKNVYGGTDSDTFSFAIDL-PPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRIV 257


>gi|5453948 protein phosphatase 1, regulatory subunit 3D [Homo
           sapiens]
          Length = 299

 Score = 84.0 bits (206), Expect = 7e-16
 Identities = 58/182 (31%), Positives = 92/182 (50%), Gaps = 15/182 (8%)

Query: 63  RVSFADSFGFNLVSVKEFDCWELPSAS----TTFDLGTDIFHTEE------YVLAPLFDL 112
           RV FAD+ G  L  VK F+  + PS      +   + +D+  + +      + L P F  
Sbjct: 102 RVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPP 161

Query: 113 PSSKEDLMQQLQIQKAILES-TESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYD 171
           P    D  ++LQ Q   LE  T S LG   I G +RV NV+FEK V VR +   W++ ++
Sbjct: 162 PVEAADFGERLQRQLVCLERVTCSDLG---ISGTVRVCNVAFEKQVAVRYTFSGWRSTHE 218

Query: 172 ILAEYV-PNSCDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFI 230
            +A +  P   +G  D F+F   + P   + GS+V F +RY+ +   +W NN+  +Y+  
Sbjct: 219 AVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLT 278

Query: 231 CQ 232
           C+
Sbjct: 279 CR 280


>gi|153792466 protein phosphatase 1, regulatory (inhibitor) subunit
           3B [Homo sapiens]
          Length = 285

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 59/189 (31%), Positives = 93/189 (49%), Gaps = 10/189 (5%)

Query: 62  RRVSFADSFGFNLVSVKEFDCWELP-----SASTTFDLGTDIFHTEEYVLAPLFDLPSSK 116
           +RVSFAD+ G  L  VK F  ++ P     + +   D    +   E       F  PS+ 
Sbjct: 61  KRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSAD 120

Query: 117 E-DLMQQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAE 175
             D   +LQ     LE+   +L   +I G ++V N++FEK V +RM+ D W+++ D   +
Sbjct: 121 YLDFRNRLQADHVCLENC--VLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQ 178

Query: 176 YVPNSCDG-ETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFICQKK 234
           YV ++  G + D FSF I L P   +   ++EF + YE +  T+W +N G NY  I  + 
Sbjct: 179 YVKDTYAGSDRDTFSFDISL-PEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAEL 237

Query: 235 EQEPEPVKP 243
           +      KP
Sbjct: 238 KSTQGMTKP 246


>gi|239757810 PREDICTED: similar to protein phosphatase 1,
           regulatory (inhibitor) subunit 3F [Homo sapiens]
          Length = 724

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 68/250 (27%), Positives = 108/250 (43%), Gaps = 76/250 (30%)

Query: 104 YVLAPLFDLPSSK---EDLMQQLQIQKAILESTESLLGSTSI----------KGIIRVLN 150
           + L P F LP +    E L + +   +A+L    ++ G   +          +G++RVLN
Sbjct: 113 FYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLN 172

Query: 151 VSFEKLVYVRMSLDDWQTHYDILAEYVPNSCD---------------------------- 182
            SFEK V+VR S D W +  D  A YVP S                              
Sbjct: 173 RSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASAS 232

Query: 183 -----GETDQFSFKIVLVPPYQK---DGSKVEFCIRYETSVGTFWSNNNGTNYTFIC--- 231
                G TD+F+F++    P+ +   DG++++F +RYET  GTFW+NN+G NYT +    
Sbjct: 233 SPDDGGRTDRFAFQL----PFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIA 288

Query: 232 ---------------QKKEQEPEP-VKPWKEVPNRQIKGCLKV----KSSKEESSVTSEE 271
                          Q  + EP+P  +   E   RQ+K C+K      + +E  +   ++
Sbjct: 289 PAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDD 348

Query: 272 NNFENPKNTD 281
           N F   ++ D
Sbjct: 349 NTFAMAEHPD 358


>gi|58761532 protein phosphatase 1, regulatory (inhibitor) subunit
           3F [Homo sapiens]
          Length = 799

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 68/250 (27%), Positives = 108/250 (43%), Gaps = 76/250 (30%)

Query: 104 YVLAPLFDLPSSK---EDLMQQLQIQKAILESTESLLGSTSI----------KGIIRVLN 150
           + L P F LP +    E L + +   +A+L    ++ G   +          +G++RVLN
Sbjct: 113 FYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLN 172

Query: 151 VSFEKLVYVRMSLDDWQTHYDILAEYVPNSCD---------------------------- 182
            SFEK V+VR S D W +  D  A YVP S                              
Sbjct: 173 RSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASAS 232

Query: 183 -----GETDQFSFKIVLVPPYQK---DGSKVEFCIRYETSVGTFWSNNNGTNYTFIC--- 231
                G TD+F+F++    P+ +   DG++++F +RYET  GTFW+NN+G NYT +    
Sbjct: 233 SPDDGGRTDRFAFQL----PFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIA 288

Query: 232 ---------------QKKEQEPEP-VKPWKEVPNRQIKGCLKV----KSSKEESSVTSEE 271
                          Q  + EP+P  +   E   RQ+K C+K      + +E  +   ++
Sbjct: 289 PAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDD 348

Query: 272 NNFENPKNTD 281
           N F   ++ D
Sbjct: 349 NTFAMAEHPD 358


>gi|223278393 protein phosphatase 1, regulatory (inhibitor) subunit
           3G [Homo sapiens]
          Length = 358

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 62/240 (25%), Positives = 92/240 (38%), Gaps = 57/240 (23%)

Query: 45  GSDSSEDIYLDTP---SSGTRRVSFADSFGFNLVSVKEFDCWELP-------SASTTFDL 94
           G + +ED  L      +   +RV FAD+ G +L SVK F   E P       S   +F +
Sbjct: 110 GGEGAEDAQLGPGGCCAKCKKRVQFADTLGLSLASVKHFSEAEEPQVPPAVLSRLRSFPM 169

Query: 95  GTDIFHTEEYVLA----------------PLFDLPSSKEDLMQQLQIQKAILESTE-SLL 137
             +       +LA                PLF LP       ++LQ Q+  LE  + S  
Sbjct: 170 RAEDLEQLGGLLAAAAVAAPLSAPPSRLRPLFQLPGPSA-AAERLQRQRVCLERVQCSTA 228

Query: 138 GSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQ---------- 187
               +KG  RVL+    + V VR +  +W++  D+ AE  P   + +  +          
Sbjct: 229 SGAEVKGSGRVLSCPGPRAVTVRYTFTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGS 288

Query: 188 -----------FSFKIVLVPPYQKD--------GSKVEFCIRYETSVGTFWSNNNGTNYT 228
                      F F + L P  Q +        G  V F + Y  + G +W NN G NYT
Sbjct: 289 GDAKKEPGAECFHFSLCLPPGLQPEDEEDADERGVAVHFAVCYRCAQGEYWDNNAGANYT 348


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 95/423 (22%), Positives = 155/423 (36%), Gaps = 53/423 (12%)

Query: 599  EHHHLTSEGSALGGITGQVCSSRTGNVLRN-DYLFQVEEK--SGGINSEDQDNSPQHK-Q 654
            E   L +  S  GG+  +  S R  N   +  YL  VEE+     + S++ D   +   Q
Sbjct: 4079 ERDRLPAVTSEEGGVAERDASERKLNRRGSMSYLAAVEEEVEESSVKSDNGDEKAEPSPQ 4138

Query: 655  SWNVLESQGKSRENKTNITEHIKGQTDCEDVWGK---RDNTRSLKATTEELFTCQETVCC 711
            SW+ L    K  E     +      T  ++ +GK    DN+ +   T + L T Q   C 
Sbjct: 4139 SWSSLWKHDKDMEEDRASSS---SGTIVQEAYGKISTSDNSMAQILTPDSLNTEQGPECS 4195

Query: 712  ELSSLADHGITEKAEAGTAYIIKTTSESTPESMSAREKA--IIAKLPQETARSDRPIEVK 769
               +  + G T   EA T           P     R +   ++     + A  +  ++  
Sbjct: 4196 LRPNQTEEGTTPPIEADTLDSSDAQGGLEPRVEKTRPEPTEVLHACKTQVAELELWLQQA 4255

Query: 770  ETAFDPHEGRNDDSHYTL------CQRDTVGVIYDNDFE----KESRLGICNVRVDEMEK 819
              A +P E  N D    L      CQ     + +   F     K+  LG       E E 
Sbjct: 4256 NVAVEP-ETLNADMQQVLEQQLVGCQAMLTEIEHKVAFLLETCKDQGLGDNGATQHEAEA 4314

Query: 820  ------------EETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDL-QL 866
                        E+   M   + + D+        T +++SS    E+Q+A   ++L +L
Sbjct: 4315 LSLKLKTVKCNLEKVQMMLQEKHSEDQHP------TILKKSSE--PEHQEALQPVNLSEL 4366

Query: 867  GMLPTDKTVFSENRDLRQVQ--ELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEIS 924
              + T++  FS  +D +Q Q  EL      D I    FN+     PQ    + +H  + +
Sbjct: 4367 ESIVTERPQFSRQKDFQQQQVLELKPMEQKDFIKFIEFNAK-KMWPQ----YCQHDNDTT 4421

Query: 925  V--STNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPEEVSRSSGI 982
               S + QA + EN V      P     +       E+    K P P+    +VS + GI
Sbjct: 4422 QESSASNQASSPENDVPDSILSPQGQNGDKWQYLHHELSSKIKLPLPQLVEPQVSTNMGI 4481

Query: 983  VTS 985
            + S
Sbjct: 4482 LPS 4484


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 95/423 (22%), Positives = 155/423 (36%), Gaps = 53/423 (12%)

Query: 599  EHHHLTSEGSALGGITGQVCSSRTGNVLRN-DYLFQVEEK--SGGINSEDQDNSPQHK-Q 654
            E   L +  S  GG+  +  S R  N   +  YL  VEE+     + S++ D   +   Q
Sbjct: 4079 ERDRLPAVTSEEGGVAERDASERKLNRRGSMSYLAAVEEEVEESSVKSDNGDEKAEPSPQ 4138

Query: 655  SWNVLESQGKSRENKTNITEHIKGQTDCEDVWGK---RDNTRSLKATTEELFTCQETVCC 711
            SW+ L    K  E     +      T  ++ +GK    DN+ +   T + L T Q   C 
Sbjct: 4139 SWSSLWKHDKDMEEDRASSS---SGTIVQEAYGKISTSDNSMAQILTPDSLNTEQGPECS 4195

Query: 712  ELSSLADHGITEKAEAGTAYIIKTTSESTPESMSAREKA--IIAKLPQETARSDRPIEVK 769
               +  + G T   EA T           P     R +   ++     + A  +  ++  
Sbjct: 4196 LRPNQTEEGTTPPIEADTLDSSDAQGGLEPRVEKTRPEPTEVLHACKTQVAELELWLQQA 4255

Query: 770  ETAFDPHEGRNDDSHYTL------CQRDTVGVIYDNDFE----KESRLGICNVRVDEMEK 819
              A +P E  N D    L      CQ     + +   F     K+  LG       E E 
Sbjct: 4256 NVAVEP-ETLNADMQQVLEQQLVGCQAMLTEIEHKVAFLLETCKDQGLGDNGATQHEAEA 4314

Query: 820  ------------EETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDL-QL 866
                        E+   M   + + D+        T +++SS    E+Q+A   ++L +L
Sbjct: 4315 LSLKLKTVKCNLEKVQMMLQEKHSEDQHP------TILKKSSE--PEHQEALQPVNLSEL 4366

Query: 867  GMLPTDKTVFSENRDLRQVQ--ELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEIS 924
              + T++  FS  +D +Q Q  EL      D I    FN+     PQ    + +H  + +
Sbjct: 4367 ESIVTERPQFSRQKDFQQQQVLELKPMEQKDFIKFIEFNAK-KMWPQ----YCQHDNDTT 4421

Query: 925  V--STNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPEEVSRSSGI 982
               S + QA + EN V      P     +       E+    K P P+    +VS + GI
Sbjct: 4422 QESSASNQASSPENDVPDSILSPQGQNGDKWQYLHHELSSKIKLPLPQLVEPQVSTNMGI 4481

Query: 983  VTS 985
            + S
Sbjct: 4482 LPS 4484


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 38.9 bits (89), Expect = 0.028
 Identities = 92/456 (20%), Positives = 168/456 (36%), Gaps = 73/456 (16%)

Query: 659  LESQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLAD 718
            LE + K R +   I E ++ +TD          TR +K   E    C E    + S+L +
Sbjct: 650  LEREHKRRTSTPVIMEGVQEETD----------TRDVKRQVERSEICTEEPQKQKSTLKN 699

Query: 719  HGITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEG 778
                +K ++ T ++     +   E  S++EK    K P E   S +           H+ 
Sbjct: 700  EKHLKKDDSETPHLKSLLKK---EVKSSKEKPEREKTPSEDKLSVK-----------HKY 745

Query: 779  RNDDSHYTLCQRDT----VGVIYDNDFEKESRLGICNVRVDEMEKEETMSMY-NPRKTHD 833
            + D  H T  + +      G+  + + +K+S+      ++   +K E  S + N RK   
Sbjct: 746  KGDCMHKTGDETELHSSEKGLKVEENIQKQSQ----QTKLSSDDKTERKSKHRNERKLSV 801

Query: 834  REKCG---TGNITSVEESSWVITEYQKATSKLDLQL------GMLPTDKTVFSENRDLRQ 884
              K G   +  I   +E+  V  E  K   +L  +           +D  +  ++   +Q
Sbjct: 802  LGKDGKPVSEYIIKTDEN--VRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQ 859

Query: 885  ----VQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEI-----------SVSTNE 929
                +Q  S+    D     + N D+N  P+      K  T+            S +  +
Sbjct: 860  HGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGK 919

Query: 930  QAIAVENAV----TTMASQPISTKSENICNSTREIQG---IEKHPYPESKPEEVSRSSGI 982
            Q   VE  +    T  A+ P   K +N   +  E Q    +E  P+ E+  E V  ++  
Sbjct: 920  QVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASS 979

Query: 983  VTSGSRKERC--IGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYT 1040
                ++K+           E+Y  +K        +  LE      H++  L  S + +  
Sbjct: 980  SAHSTQKDSSHRAKLPLAKEKYKSDKDS-----TSTRLERKLSDGHKSRSLKHSSKDIKK 1034

Query: 1041 SGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKI 1076
              E +SD      +     +A+GN SL  K  + ++
Sbjct: 1035 KDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRL 1070


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 37.7 bits (86), Expect = 0.062
 Identities = 111/746 (14%), Positives = 263/746 (35%), Gaps = 38/746 (5%)

Query: 260  SSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKEL 319
            S+  +SS +S+ ++ ++  ++D+          D +  ++S+ +  D +   D  +  + 
Sbjct: 558  SNSSDSSDSSDSDSSDSNSSSDS-------DSSDSDSSDSSDSDSSDSSNSSDSSDSSDS 610

Query: 320  ELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQIHGEICTDLFQRSLSPSSS 379
                +     + S+ S+ + +   +D  +  +K++  +         +D    S S +SS
Sbjct: 611  SDSSDS----SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 380  --AESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDELVQLHTGSKEV 437
              ++SS   D   +   S+  D +       +S   +   S    SSD     ++ S + 
Sbjct: 667  DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726

Query: 438  LDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEG-----GAKNIEVKDLGCLRRDFHSD 492
               N++ +  +        SSD   + + +   +       + + +  D         S+
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786

Query: 493  TSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHDQERKMGNPKISV 552
             S+   +S++  +S +    +   D         +     +  +   D      +   S 
Sbjct: 787  DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846

Query: 553  AGIG----ASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEHHHLTSEGS 608
            +  G    +SNR  ++  S+ +     + ++D S S  +N S   +  +   +   S+ S
Sbjct: 847  SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906

Query: 609  ALGG------ITGQVCSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQSWNVLESQ 662
                       +    SS + N   N         S   +S D  NS     S +   S 
Sbjct: 907  DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966

Query: 663  GKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHGIT 722
              S  N ++ ++     +D  D     D++ S  ++     +         +S      +
Sbjct: 967  DSSDSNSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025

Query: 723  EKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRNDD 782
            + + +  +     +S+S+  S S+           +++ S    +  +++       + D
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDS--------SDSSNSSDSSDSSDSSDSSDSSDSSD 1077

Query: 783  SHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTGNI 842
            S  +    D+      +D    S     +   D  +  ++    N   + D       + 
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137

Query: 843  TSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAF 902
            +S    S   +E   ++   D       +D +  S++ D     + S  +DS     S+ 
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197

Query: 903  NSDTNRAPQNS-SPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREIQ 961
            +SD++ +  +S S  S   ++ S S++    +  N  +  +    S+ S N  +S+    
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257

Query: 962  GIEKHPYPESKPEEVSRSSGIVTSGS 987
              +       + +  S+S     +GS
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGS 1283



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 123/805 (15%), Positives = 280/805 (34%), Gaps = 50/805 (6%)

Query: 263  EESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELM 322
            ++S  TS+ NN ++  N +        S   K   ++S+ +  D +   D  +  + +  
Sbjct: 513  DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572

Query: 323  INQHLIRTRSTAS--RDERNTFSTDPVNFPNKAEGLEKKQIH--GEICTDLFQRSLSPSS 378
             +     + S+ S   D  ++ S+D  N  + ++  +        +        S S S 
Sbjct: 573  DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632

Query: 379  SAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPS-LGDTSSDELVQLHTGSKEV 437
            S++S  K D   +    S D+     S  ++++      S   D+SS       + S + 
Sbjct: 633  SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 438  LDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCLRRDFHSDTSACL 497
             D + +    + +      SSD   + N N      + + +  D         SD+S   
Sbjct: 693  SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS--NSSDSSDSSDSS 750

Query: 498  KESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHDQERKMGNPKISVAGIGA 557
              S    SS      +  D  +       +     N  +   D      +   S +   +
Sbjct: 751  NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810

Query: 558  SNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEHHHLTSEGSALGGITGQV 617
             + D +   S +++  + +  +D S S  ++ S + +  +      +S  S     +   
Sbjct: 811  DSSDSSDSDSSNSSDSSNS--SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868

Query: 618  CSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIK 677
             SS + N           + S   +S +  NS     S N  +S      N ++ ++   
Sbjct: 869  DSSDSSNS---------SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-S 918

Query: 678  GQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHGITEKAEAGTAYIIKTTS 737
              +D  +     DN+ S  ++         +   + S+ +D   +  +   +      +S
Sbjct: 919  NSSDSSESSNSSDNSNSSDSSNSS----DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974

Query: 738  ESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIY 797
            +S+  S S+           +++ S    +  +++   +   + DS  +    ++     
Sbjct: 975  DSSDSSNSS-----------DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023

Query: 798  DNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQK 857
             +D    S     +   D  +  ++    +   + D       + +S    S   ++  +
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083

Query: 858  ATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFS 917
            ++   D       +D +  S++ D     + S  +DS     S+ +SD++ +  +S+   
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143

Query: 918  KHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPEEVS 977
               +  S  +++ + + +++ ++ +S   S+ S +  NS+      +     +S     S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSD--SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201

Query: 978  RSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQS 1037
              S   +  S           ++      S               E+   ++   SS  S
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDS--------------NESSDSSDSSDSSDSS 1247

Query: 1038 LYTSGEKESDSSASTSLPVEESQAQ 1062
              +     SDSS STS   +ES +Q
Sbjct: 1248 NSSDSSDSSDSSDSTSDSNDESDSQ 1272



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 116/749 (15%), Positives = 270/749 (36%), Gaps = 72/749 (9%)

Query: 245  KEVPNRQIKGCLKVKSSKEESSVTSEEN-----------NFENPKNTDTYIPTIICSH-- 291
            KE P+ ++ G  K   S+E S+   E+N           N    K  +  I     +H  
Sbjct: 310  KEDPHNEVDGD-KTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAV 368

Query: 292  ---EDK----EDLEASNRNV-KDVNREHDEHNEK-ELELMINQHLIRTRSTASRDERNTF 342
               +DK    +   + NRN+ K+V + ++   +K +  +++ +  ++T+      E    
Sbjct: 369  GKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQ 428

Query: 343  STDPVNFPNKAEGLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTH 402
             ++P N          K  H    +D            + S++GD   +   S+G+D  +
Sbjct: 429  KSEPGN----------KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDAN 478

Query: 403  QPSEETTSNMGEIKPSLGDT-----SSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPS 457
              S+  +S+ G+   +  ++      SD        S    D N + ++GNG        
Sbjct: 479  SESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGN------- 531

Query: 458  SDQLMAGNLNKKHEGGAKNIEVKDLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDD 517
                   + N K + G    +  D         SD+S      + + +S  D   +  D 
Sbjct: 532  ----NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS 587

Query: 518  EEQRIYLGVNEKQRKNFQTILHDQERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAI 577
             +       ++    +        +    +     +    S  D +   S+ +   +++ 
Sbjct: 588  SDS------SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641

Query: 578  TADVSHSPRTNLSWEEAVLTPEHHHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVEEK 637
            ++D + S  ++ S         +   +S+ S     +    SS + +   +       E 
Sbjct: 642  SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 638  SGGINSEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKA 697
            S   +S D D+S     S +       S  + ++ + +    +D  D     D++ S  +
Sbjct: 702  SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761

Query: 698  --TTEELFTCQETVCCELSSLADHG-------ITEKAEAGTAYIIKTTSESTPESMSARE 748
              +++   +   +   + S+ +D          ++ + +  +     +S+S+  S S   
Sbjct: 762  SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821

Query: 749  KAIIAKLPQETARSDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIYDNDFEKESRLG 808
             +  +    +++ S    +  +++ D  +G + DS     + D+      +D    S   
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSS-DSSDGSDSDSSN---RSDSSNSSDSSDSSDSSNSS 877

Query: 809  ICNVRVDEMEKEETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDLQLGM 868
              +   D  E   +    +   + D +   + N +   +SS      + + S  +     
Sbjct: 878  DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN--- 934

Query: 869  LPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTN 928
              +D +  S++ D       S  ++S    +S+ +SD+N +  + S  S   ++ S S++
Sbjct: 935  -SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993

Query: 929  EQAIAVENAVTTMASQPISTKSENICNST 957
                +  +  +  +    S+ S N  +S+
Sbjct: 994  SSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 71/434 (16%), Positives = 157/434 (36%), Gaps = 22/434 (5%)

Query: 642  NSEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEE 701
            ++ D +NS  +    N  +   KS   K          +D  +     D++ S  ++   
Sbjct: 517  STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS-DSSDSN 575

Query: 702  LFTCQETVCCELSSLADHGITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETAR 761
              +  ++   + S  +D   ++ + +  +     +S+S+  S S+  K+  +K   +++ 
Sbjct: 576  SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635

Query: 762  SDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEE 821
            SD     K  + D +   + D+               +D    S     +   D  +  +
Sbjct: 636  SDS----KSDSSDSNSSDSSDN---------------SDSSDSSNSSNSSDSSDSSDSSD 676

Query: 822  TMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRD 881
            + S  +   + D       + +S    S   ++   + S          +D +  S++ D
Sbjct: 677  SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 882  LRQVQELSKKTDSDAIVHSAFNSDTNRAPQNS-SPFSKHHTEISVSTNEQAIAVENAVTT 940
                 + S  +DS     S+ +SD++ +  +S S  S   ++ S S++    +  +  + 
Sbjct: 737  SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796

Query: 941  MASQPISTKSENICNSTREIQGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTE 1000
             ++   S+ S +  +S+        +    S   + S SS    S    +   G    + 
Sbjct: 797  SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856

Query: 1001 EYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQ 1060
              S + S       +    N  ++   ++   SS  S  +     SDS +S S    +S 
Sbjct: 857  NRS-DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915

Query: 1061 AQGNESLFSKYTNS 1074
               N S  S+ +NS
Sbjct: 916  DSSNSSDSSESSNS 929


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 59/278 (21%), Positives = 108/278 (38%), Gaps = 26/278 (9%)

Query: 797  YDNDFEKESRLGICNVRVDEMEKE---ETMSMYNPRKTHDREKCGTGNITS------VEE 847
            Y  D E  +R      R  E ++E   E M + N   +   +   T  +T       ++ 
Sbjct: 491  YVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKN 550

Query: 848  SSWVITEYQKATSKLDLQLGMLPT-----DKTVFSENRDLRQ-VQELSKK---TDSDAIV 898
            +S +  E   A S+L ++L  L        +      +DL+Q   ELS+K   +D + +V
Sbjct: 551  ASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLV 610

Query: 899  HSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTK--SENICNS 956
              A   D +   +N   +     E +         + +AV+ + +Q I  K  SEN+ N 
Sbjct: 611  QKAL--DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQ 668

Query: 957  TREIQGIEKHPYPESKPEEVSRSSGIVTSGS----RKERCIGQIFQTEEYSVEKSLGPMI 1012
             RE+Q   +    E+  +   R  G +   S    R    + Q+   E    ++ LG   
Sbjct: 669  ARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSR 728

Query: 1013 LINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSA 1050
            LI +          +    +++  + ++   +  DSSA
Sbjct: 729  LITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSA 766


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 59/278 (21%), Positives = 108/278 (38%), Gaps = 26/278 (9%)

Query: 797  YDNDFEKESRLGICNVRVDEMEKE---ETMSMYNPRKTHDREKCGTGNITS------VEE 847
            Y  D E  +R      R  E ++E   E M + N   +   +   T  +T       ++ 
Sbjct: 498  YVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKN 557

Query: 848  SSWVITEYQKATSKLDLQLGMLPT-----DKTVFSENRDLRQ-VQELSKK---TDSDAIV 898
            +S +  E   A S+L ++L  L        +      +DL+Q   ELS+K   +D + +V
Sbjct: 558  ASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLV 617

Query: 899  HSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTK--SENICNS 956
              A   D +   +N   +     E +         + +AV+ + +Q I  K  SEN+ N 
Sbjct: 618  QKAL--DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQ 675

Query: 957  TREIQGIEKHPYPESKPEEVSRSSGIVTSGS----RKERCIGQIFQTEEYSVEKSLGPMI 1012
             RE+Q   +    E+  +   R  G +   S    R    + Q+   E    ++ LG   
Sbjct: 676  ARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSR 735

Query: 1013 LINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSA 1050
            LI +          +    +++  + ++   +  DSSA
Sbjct: 736  LITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSA 773


>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 59/278 (21%), Positives = 108/278 (38%), Gaps = 26/278 (9%)

Query: 797  YDNDFEKESRLGICNVRVDEMEKE---ETMSMYNPRKTHDREKCGTGNITS------VEE 847
            Y  D E  +R      R  E ++E   E M + N   +   +   T  +T       ++ 
Sbjct: 491  YVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKN 550

Query: 848  SSWVITEYQKATSKLDLQLGMLPT-----DKTVFSENRDLRQ-VQELSKK---TDSDAIV 898
            +S +  E   A S+L ++L  L        +      +DL+Q   ELS+K   +D + +V
Sbjct: 551  ASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLV 610

Query: 899  HSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTK--SENICNS 956
              A   D +   +N   +     E +         + +AV+ + +Q I  K  SEN+ N 
Sbjct: 611  QKAL--DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQ 668

Query: 957  TREIQGIEKHPYPESKPEEVSRSSGIVTSGS----RKERCIGQIFQTEEYSVEKSLGPMI 1012
             RE+Q   +    E+  +   R  G +   S    R    + Q+   E    ++ LG   
Sbjct: 669  ARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSR 728

Query: 1013 LINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSA 1050
            LI +          +    +++  + ++   +  DSSA
Sbjct: 729  LITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSA 766


>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
            sapiens]
          Length = 1283

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 18/141 (12%)

Query: 371  QRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSS--DELV 428
            +R   PS  A+  V G+  C+ +  +       PSE+TT   G  KP LG +SS   +L 
Sbjct: 1009 ERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTT-EFGIHKPHLGKSSSLDKQLP 1067

Query: 429  QLHTGSKEVLDDNANPAHGNGTV---QIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCL 485
                G +E    N +P+   GT     +P PS  ++    +       A +         
Sbjct: 1068 GPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFP--VTHSFPSSAHS--------- 1116

Query: 486  RRDFHSDTSACLKESTEEGSS 506
                H+ T+   K++T EGS+
Sbjct: 1117 -DTHHTSTAESQKKATAEGSA 1136


>gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 612

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 18/141 (12%)

Query: 371 QRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSS--DELV 428
           +R   PS  A+  V G+  C+ +  +       PSE+TT   G  KP LG +SS   +L 
Sbjct: 338 ERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTT-EFGIHKPHLGKSSSLDKQLP 396

Query: 429 QLHTGSKEVLDDNANPAHGNGTV---QIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCL 485
               G +E    N +P+   GT     +P PS  ++    +       A +         
Sbjct: 397 GPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFP--VTHSFPSSAHS--------- 445

Query: 486 RRDFHSDTSACLKESTEEGSS 506
               H+ T+   K++T EGS+
Sbjct: 446 -DTHHTSTAESQKKATAEGSA 465


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 52/223 (23%), Positives = 92/223 (41%), Gaps = 20/223 (8%)

Query: 665 SRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHGITEK 724
           SR+N+  I++  K Q   ED+  K+   +SLK+    L      V C+  S  +  IT  
Sbjct: 274 SRQNEKEISQ--KCQVLDEDIDAKQKEIQSLKSQISALQKGYSKVLCQTLSERNSEITSL 331

Query: 725 AEAGTAYIIKTTSESTPESMSAREKAIIAK------LPQETARSDRPIEVKETAFDPHEG 778
              G    +K  +  T   +S+ +K I+AK      L +E +      + K+   +    
Sbjct: 332 KNEGEN--LKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGS 389

Query: 779 RNDDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCG 838
           R       L Q D    + +    +E  L +C  ++ +MEKE         +   R+ C 
Sbjct: 390 RCSVLKEELKQEDAHRELRE---AQEKELKLCKTQIQDMEKE-----MKKLRAELRKSCT 441

Query: 839 TGNITS--VEESSWVITEYQKATSKLDLQLGMLPTDKTVFSEN 879
             ++ S  + E S V  + Q+ + +  LQL  +   ++V   N
Sbjct: 442 EQSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNRESVIKIN 484


>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapiens]
          Length = 1906

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 34/146 (23%), Positives = 58/146 (39%), Gaps = 13/146 (8%)

Query: 367  TDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDE 426
            +DL   SLS           +    EK   G DC+     E+T    +  P L   +S  
Sbjct: 947  SDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSS 1006

Query: 427  LVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCLR 486
            +V+L TG+    +++A    G      P    + L+  +L   +E   +NI+ +   C R
Sbjct: 1007 IVRL-TGTS---NNSAGKISGESMESTP----ELLLISSLEDTNE--TRNIQSR---CFR 1053

Query: 487  RDFHSDTSACLKESTEEGSSKEDYYG 512
            +   SD    L++    G+   +  G
Sbjct: 1054 KRHKSDNETNLQQQVVWGNRNRNLSG 1079


>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapiens]
          Length = 1863

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 34/146 (23%), Positives = 58/146 (39%), Gaps = 13/146 (8%)

Query: 367  TDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDE 426
            +DL   SLS           +    EK   G DC+     E+T    +  P L   +S  
Sbjct: 904  SDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSS 963

Query: 427  LVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCLR 486
            +V+L TG+    +++A    G      P    + L+  +L   +E   +NI+ +   C R
Sbjct: 964  IVRL-TGTS---NNSAGKISGESMESTP----ELLLISSLEDTNE--TRNIQSR---CFR 1010

Query: 487  RDFHSDTSACLKESTEEGSSKEDYYG 512
            +   SD    L++    G+   +  G
Sbjct: 1011 KRHKSDNETNLQQQVVWGNRNRNLSG 1036


>gi|41393608 reticulon 3 isoform b [Homo sapiens]
          Length = 1013

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 79/354 (22%), Positives = 137/354 (38%), Gaps = 69/354 (19%)

Query: 739  STPESMSAREKAIIAKLPQETARSDRPI-----EVKETAFDPHEGRNDDSHYTLCQRDTV 793
            STP + S  + A  A L QE A + +P+       KE +    +G          Q DT+
Sbjct: 376  STPITKSTGDWAE-ASLQQENAITGKPVPDSLNSTKEFSIKGVQGNMQK------QDDTL 428

Query: 794  GVIYDNDFEKESRLG--ICNVRV----DEMEKEETMSMYNPRKTHDREKCGTGNITSVEE 847
              +  +  EK   LG  +  V+V    D ++ E         +  + +  G  + T +E+
Sbjct: 429  AELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGESDDTVIED 488

Query: 848  SSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQ--ELSKKTD-------SDAIV 898
               +  +     +K+  +  +      V +  R+++++   E  +KT        SD+ +
Sbjct: 489  ---ITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELVSDSEL 545

Query: 899  HSAFNSDTNRAPQNSSPFSK-HHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNST 957
            H        R+P + +  SK   T +S+    + +A E  +TT   +  ST S N+ N T
Sbjct: 546  HQDQPDILGRSPASEAACSKVPDTNVSLEDVSE-VAPEKPITTENPKLPSTVSPNVFNET 604

Query: 958  REIQGIEKHPYPE------------SKPEEV------SRSSGIVTSGSRKERCIGQIFQT 999
                 +    Y E            S PE++      +R  GIV S     + I     +
Sbjct: 605  EFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAI-----S 659

Query: 1000 EEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSASTS 1053
            E+ +  K+  P+           E  HENE   S G  +   G K S+ S  T+
Sbjct: 660  EKMTDFKTTPPV-----------EVLHENE---SGGSEIKDIGSKYSEQSKETN 699


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 57/289 (19%), Positives = 108/289 (37%), Gaps = 32/289 (11%)

Query: 238 PEPVKPWKEVPNRQIKGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDL 297
           P PVK  K+  +++ K        +  SS + +    +  ++          SH  +   
Sbjct: 128 PSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187

Query: 298 -----EASNRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNK 352
                ++S          H   + +E +    +H  R   T  +D     S+ P + P +
Sbjct: 188 CPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQ 247

Query: 353 AEGLEKKQ--IHGE-ICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETT 409
             G    +  I G     DLF ++ SP +++          +++Y SG+D +  PS +T+
Sbjct: 248 MLGYLSARGVITGSGSAADLFTKTASPLTTSRGR-------SQEYDSGNDTSSPPSTQTS 300

Query: 410 S--NMGEIK--PSLGDTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGN 465
           S  + G+ K  PS G + S EL            ++ N +    +     P +   M  N
Sbjct: 301 SARSRGQEKGSPSGGLSKSREL------------NSGNTSDSGNSFTTSSPQNKGAMLEN 348

Query: 466 LNKKHEG-GAKNIEVKDLGCLRRDFHSDTSACLKESTEEGSSKEDYYGN 513
           L+    G  ++  +   L C      S   +  + S  +G S+   Y +
Sbjct: 349 LSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAS 397


>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
          Length = 1790

 Score = 35.4 bits (80), Expect = 0.31
 Identities = 43/203 (21%), Positives = 77/203 (37%), Gaps = 43/203 (21%)

Query: 878  ENRD-LRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVEN 936
            E++D L+   +  + T+S        +SD     +  S FS+  T    S +E     E 
Sbjct: 1582 EDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEE 1641

Query: 937  AVTTMASQPISTKSEN--------------ICNSTREIQGIEKHPYPESKPEEVSRSSGI 982
            + T  + +  ST+SE               +    +E++G ++ P  E K  ++      
Sbjct: 1642 SSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKM------ 1695

Query: 983  VTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSG 1042
                           + EE+S E+  GP      P+E   +   ++     S +S    G
Sbjct: 1696 ---------------EEEEHSEEEESGP-----APVEESTDPEAQDIPEEGSAESASVEG 1735

Query: 1043 --EKESDSSASTSLPVEESQAQG 1063
              E E +S + +S    ESQ+ G
Sbjct: 1736 GVESEEESESGSSSSSSESQSGG 1758


>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
            sapiens]
          Length = 1188

 Score = 34.7 bits (78), Expect = 0.52
 Identities = 41/177 (23%), Positives = 71/177 (40%), Gaps = 40/177 (22%)

Query: 760  ARSDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEK 819
            + SD  IEV   A +  EG        LC+R++      N FE     G C++ V E E 
Sbjct: 1021 SESDITIEVDSIAEESQEG--------LCERESA-----NGFETNVASGTCSIIVQERES 1067

Query: 820  EE---------------TMSMYNPRKTH---DREKCGT---GNITSVEESSWVITEYQKA 858
             E                     P++T      EK GT    N+ S E  S++  + Q  
Sbjct: 1068 REKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFLQEKLQ-- 1125

Query: 859  TSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSP 915
                +++   +     V + +R  +++++  ++        S+ +SDT  +P +SSP
Sbjct: 1126 ----EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSP 1178


>gi|39812492 TH1-like protein [Homo sapiens]
          Length = 590

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 20/97 (20%)

Query: 105 VLAPLFDLPSSKEDLMQQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLD 164
           +L  LF+   S+ D+M+QL+++K +L+    LL    +  ++           Y+R  L+
Sbjct: 472 LLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVS----------YIRKCLE 521

Query: 165 DWQTHYDILAEYVPNSCDGETDQFSFKIVLVPPYQKD 201
              T   ++  +V    D          V+ PPY  D
Sbjct: 522 KLDTDISLIRYFVTEVLD----------VIAPPYTSD 548


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 34.3 bits (77), Expect = 0.68
 Identities = 50/213 (23%), Positives = 82/213 (38%), Gaps = 38/213 (17%)

Query: 889  SKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPIST 948
            S KT+    V  +  +D  R P + S  ++ H  +S    E+ + V  +  T   QP+ST
Sbjct: 1895 STKTERHPPVSPSGKTD-KRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQPVST 1953

Query: 949  KSENICNSTREIQG-IEKHP--YPESKPEEVSRS--------------------SGIVTS 985
              +   +      G  EK P   P SK E +  +                    +G+   
Sbjct: 1954 AGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEH 2013

Query: 986  GSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKE 1045
             S K++   Q  +  +  VEK  GP++          EA+      +  GQ L  +G  E
Sbjct: 2014 KSAKQK---QPQEKGKVRVEKEKGPIL-------TQREAQKTENQTIKRGQRLPVTGTAE 2063

Query: 1046 SDSSAS-TSLPVEESQAQGNESLFSKYTNSKIP 1077
            S      +S+ V++  A G +    K  + KIP
Sbjct: 2064 SKRGVRVSSIGVKKEDAAGGK---EKVLSHKIP 2093


>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
          Length = 580

 Score = 33.9 bits (76), Expect = 0.89
 Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 17/170 (10%)

Query: 230 ICQKKEQEPEPVKPWKEVPNRQIKGCLKVKSSKEES-SVTSEENNFENPKNTDTYIPTII 288
           +C K + E EPV    ++ +R +  C+    +  E+ SVTSEEN+    K       +  
Sbjct: 267 VCNKADAESEPVAQKSQL-DRTV--CISDAGACGETLSVTSEENSLVKKKERSLSSGSNF 323

Query: 289 CSHEDKEDLEASNRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVN 348
           CS +    +     + KD      EHNEK  +  +    I T+     + +    TD + 
Sbjct: 324 CSEQKTSGIINKFCSAKD-----SEHNEKYEDTFLESEEIGTKVEVV-ERKEHLHTDILK 377

Query: 349 FPNKAE---GLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYS 395
             ++ +      +K   GE    +FQ    P +  E   K   Y + KY+
Sbjct: 378 RGSEMDNNCSPTRKDFTGE---KIFQEDTIPRTQIERR-KTSLYFSSKYN 423


>gi|13376834 zinc finger and SCAN domain containing 16 [Homo
           sapiens]
          Length = 348

 Score = 33.9 bits (76), Expect = 0.89
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 17/130 (13%)

Query: 536 TILHDQERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAV 595
           T+L D ER++  P   V G  +  RD+          P  ++T  + H  +T L  E   
Sbjct: 114 TVLEDLERELDEPGKQVPG-NSERRDILMDKLAPLGRPYESLTVQL-HPKKTQLEQEAG- 170

Query: 596 LTPEHHHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQS 655
             P+ +             G    ++   + + + + + +E  G IN     ++PQH +S
Sbjct: 171 -KPQRN-------------GDKTRTKNEELFQKEDMPKDKEFLGEINDRLNKDTPQHPKS 216

Query: 656 WNVLESQGKS 665
            +++E++G+S
Sbjct: 217 KDIIENEGRS 226


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 33.9 bits (76), Expect = 0.89
 Identities = 95/458 (20%), Positives = 159/458 (34%), Gaps = 76/458 (16%)

Query: 253 KGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHD 312
           K C+K  +S+      SE +  E PK T    P+     E     EA      DV+   D
Sbjct: 443 KSCIKAAASQGAEKTVSEVS--EQPKETSMTEPS-----EPGSKAEAKKALGGDVS---D 492

Query: 313 EHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQIHGEICTDL-FQ 371
           +  E   + +    +  + S+           +    P    G     +  +  T L + 
Sbjct: 493 QSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWP 552

Query: 372 RSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDELVQLH 431
             L   + AE S+   + CN  Y    D     +++  +   E    +G +S D L  L 
Sbjct: 553 SELLIFTKAEPSIS--YSCNPLYF---DFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLD 607

Query: 432 TG----SKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLG---- 483
            G    SKEV  +    + G    ++  P+S    +G LNK+  GG+   E +D G    
Sbjct: 608 PGEPNKSKEVGGEKIVRSSGG---RMDAPASGSACSG-LNKQEPGGSHGSETEDTGRSLP 663

Query: 484 -----------CLRRDFHSDTSACL---KESTEEGSSKEDYYGNGKDDEEQRIYLGVNEK 529
                        ++  H  +S      K  TEE SSK +   +G+  ++++       K
Sbjct: 664 SKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAE---SGEKSKKRK-----KRK 715

Query: 530 QRKNFQTILHDQERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNL 589
           ++KN  +   D ER    PK    G G             +  P R        S R +L
Sbjct: 716 RKKNKSSAPADSER---GPKPEPPGSG-------------SPAPPRRRRRAQDDSQRRSL 759

Query: 590 SWEEAVLTPEHHHLTSEGSA-------LGGITGQVCSSRTGNVLRNDYLFQVEEKSGGIN 642
             EE     +        S         G +    C  R G    +    + +  SG   
Sbjct: 760 PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSG--- 816

Query: 643 SEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIKGQT 680
            ED D++  H+          +  E + + +EH + ++
Sbjct: 817 DEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRS 854


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 33.9 bits (76), Expect = 0.89
 Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 20/129 (15%)

Query: 845 VEESSWVITEYQKATSKLDLQLGML------PTDKT--VFSENRDLRQVQELSKKT---- 892
           V E ++  +E   A  + DL +  L      P+ KT   F + R LR+ ++  + T    
Sbjct: 550 VSEITFPHSEISNAVKRTDLTINCLAEGASSPSPKTNNAFPQQRILREARKCLQTTPTTH 609

Query: 893 --DSDAIVHSAFNSDTNRAPQNSSPFSK--HHTEISVSTNEQAIAVENAVTTMASQPIST 948
             D++ I     N+D++ A  NS  +SK  H  E +          E      A+   +T
Sbjct: 610 CADNNTIAARFLNNDSSGAEANSEKYSKILHCPEFATDLPSSQTDPE----VNAAGAAAT 665

Query: 949 KSENICNST 957
           K+EN C  T
Sbjct: 666 KAENPCTDT 674


>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
          Length = 645

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 1/75 (1%)

Query: 857 KATSKLDLQLGMLPTDKTVFS-ENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSP 915
           K + KLD  L  +   +T F  E +D    QE +     +    S  NSD   + QNSSP
Sbjct: 48  KLSDKLDQDLDNIQIQETYFEDEEQDNDWSQEDANSLFLEVDHFSCCNSDLQDSAQNSSP 107

Query: 916 FSKHHTEISVSTNEQ 930
               H + S ST  Q
Sbjct: 108 SLSQHAKDSCSTMSQ 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,343,806
Number of Sequences: 37866
Number of extensions: 2115550
Number of successful extensions: 5706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 5578
Number of HSP's gapped (non-prelim): 181
length of query: 1122
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1009
effective length of database: 13,968,660
effective search space: 14094377940
effective search space used: 14094377940
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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