Guide to the Human Genome
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Search of human proteins with 11072101

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11072101 rhomboid domain containing 3 [Homo sapiens]
         (386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11072101 rhomboid domain containing 3 [Homo sapiens]               788   0.0  
gi|94818790 rhomboid domain containing 2 isoform a [Homo sapiens]      61   2e-09
gi|112421108 capicua homolog [Homo sapiens]                            40   0.005
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]        36   0.067
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]        36   0.067
gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]     35   0.088
gi|41152107 ubiquitin-like 7 [Homo sapiens]                            35   0.11 
gi|14249682 ubiquitin-like 7 [Homo sapiens]                            35   0.11 
gi|7706117 solute carrier family 15, member 3 [Homo sapiens]           35   0.15 
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    34   0.25 
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              34   0.25 
gi|148539835 dystroglycan 1 preproprotein [Homo sapiens]               33   0.33 
gi|24797153 faciogenital dysplasia protein [Homo sapiens]              33   0.33 
gi|94818879 rhomboid domain containing 2 isoform b [Homo sapiens]      33   0.33 
gi|19924103 synapsin II isoform IIa [Homo sapiens]                     33   0.43 
gi|19924101 synapsin II isoform IIb [Homo sapiens]                     33   0.43 
gi|119220575 mediator complex subunit 24 isoform 2 [Homo sapiens]      33   0.43 
gi|41281496 mediator complex subunit 24 isoform 1 [Homo sapiens]       33   0.43 
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    33   0.57 
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]              33   0.57 
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]               33   0.57 
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         32   0.74 
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                 32   0.74 
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...    32   0.74 
gi|238859557 regulatory factor X1 [Homo sapiens]                       32   0.97 
gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchan...    32   0.97 
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ...    32   0.97 
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s...    32   0.97 
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...    32   0.97 
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]      32   0.97 

>gi|11072101 rhomboid domain containing 3 [Homo sapiens]
          Length = 386

 Score =  788 bits (2035), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MHARGPHGQLSPALPLASSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGH 60
           MHARGPHGQLSPALPLASSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGH
Sbjct: 1   MHARGPHGQLSPALPLASSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGH 60

Query: 61  TALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLAGLGLSSAAGSCG 120
           TALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLAGLGLSSAAGSCG
Sbjct: 61  TALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLAGLGLSSAAGSCG 120

Query: 121 YMPVHLAMLAGEGHRPRRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAA 180
           YMPVHLAMLAGEGHRPRRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAA
Sbjct: 121 YMPVHLAMLAGEGHRPRRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAA 180

Query: 181 GAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPY 240
           GAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPY
Sbjct: 181 GAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPY 240

Query: 241 VASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEG 300
           VASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEG
Sbjct: 241 VASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEG 300

Query: 301 IQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQAVVALAATGRVEGAVSLLV 360
           IQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQAVVALAATGRVEGAVSLLV
Sbjct: 301 IQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQAVVALAATGRVEGAVSLLV 360

Query: 361 GGQVGTETLVTHGKGGPAHSEGPGPP 386
           GGQVGTETLVTHGKGGPAHSEGPGPP
Sbjct: 361 GGQVGTETLVTHGKGGPAHSEGPGPP 386


>gi|94818790 rhomboid domain containing 2 isoform a [Homo sapiens]
          Length = 364

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 85/320 (26%), Positives = 134/320 (41%), Gaps = 44/320 (13%)

Query: 1   MHARGPHGQ---LSPALPLAS---SVLMLLMS--TLWLVG---AGPGLVLAPELLLDPWQ 49
           M A GP  +   L P +P A+   ++L LL+S   L+L+    A  GL L  E L + WQ
Sbjct: 1   MAASGPGCRSWCLCPEVPSATFFTALLSLLVSGPRLFLLQQPLAPSGLTLKSEALRN-WQ 59

Query: 50  VHRLLTHALGHTALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLAG 109
           V+RL+T+   +     LL   +++       E  +GT+R    + + A+ S ++ +    
Sbjct: 60  VYRLVTYIFVYENPISLLCGAIIIWRFAGNFERTVGTVRHCFFTVIFAIFSAIIFLSFEA 119

Query: 110 LGLSSAAGSC----GYMPVHLAMLAGEGHRPRRPRG-----ALPPWLSPWLLLALTPLLS 160
           +   S  G      G+ PV  AML     R R  R       +P  L PWLLL  + L+ 
Sbjct: 120 VSSLSKLGEVEDARGFTPVAFAMLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLI- 178

Query: 161 SEPPFLQLLCGLLAGLAYAAGAFRWLEPSER---------RLQVLQEGVLCRTLAGCWPL 211
            +  FL  +CGL  GLAY       ++ SER            +++   + + ++G    
Sbjct: 179 PQTSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAE 238

Query: 212 RLLATPGSLAELPVTHPAGVRPPIPGPPYVASPDLWSHWEDSALPP-------PSLRPVQ 264
           R  A    L  +P ++P     P   P +  S    +  +  A  P       P+L P Q
Sbjct: 239 RRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQ 298

Query: 265 PTWEGSSEAGLDWAGASFSP 284
           P       +GL +    F P
Sbjct: 299 PA------SGLCYVQNHFGP 312


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 9/65 (13%)

Query: 217  PGSLAELPVTHPAGVRP-PIPGPPYVASPDLWSHWEDSAL--------PPPSLRPVQPTW 267
            PG+ A LPV  P G    P P P     PD  S   DS          PPP   P QP W
Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW 1588

Query: 268  EGSSE 272
            EG+ +
Sbjct: 1589 EGAPQ 1593


>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
          Length = 930

 Score = 35.8 bits (81), Expect = 0.067
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 7/56 (12%)

Query: 212 RLLATPGSLAELPVTHPAGVRPPIPGPP-------YVASPDLWSHWEDSALPPPSL 260
           RL   PGS  +LP   P    PP PGPP       ++  P+L  H +  ALP  +L
Sbjct: 432 RLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATL 487


>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
          Length = 775

 Score = 35.8 bits (81), Expect = 0.067
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 7/56 (12%)

Query: 212 RLLATPGSLAELPVTHPAGVRPPIPGPP-------YVASPDLWSHWEDSALPPPSL 260
           RL   PGS  +LP   P    PP PGPP       ++  P+L  H +  ALP  +L
Sbjct: 277 RLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATL 332


>gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]
          Length = 209

 Score = 35.4 bits (80), Expect = 0.088
 Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 15/98 (15%)

Query: 18  SSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGHTALPG---------LLL 68
           S +L L + T  L  AG  + L    LL  W V  LL   LG  A+ G         +L 
Sbjct: 15  SRILGLSLGTAALFAAGANVAL----LLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLT 70

Query: 69  SLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVL 106
           + +L+  +GW+  C   +   L  S L AL SG LA+L
Sbjct: 71  AAILISLMGWRYGCF--SKSGLCRSVLTALLSGGLALL 106


>gi|41152107 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 18/151 (11%)

Query: 215 ATPGSLAELPVTHPAGVR-PPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEA 273
           +TP S    P + PA +      GP  +   +L +    ++ P  S     P  +G S +
Sbjct: 242 STPSS--STPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHS-S 298

Query: 274 GLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLE 333
           G     +    GTP+   L  Q LQ  +QAS    P+ + Q  P          +LQQL 
Sbjct: 299 GTSPMSSGVQSGTPITNDLFSQALQHALQAS--GQPSLQSQWQP----------QLQQLR 346

Query: 334 RMGFPTEQ-AVVALAAT-GRVEGAVSLLVGG 362
            MG   ++ ++ AL AT G ++ A+ L+  G
Sbjct: 347 DMGIQDDELSLRALQATGGDIQAALELIFAG 377


>gi|14249682 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 18/151 (11%)

Query: 215 ATPGSLAELPVTHPAGVR-PPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEA 273
           +TP S    P + PA +      GP  +   +L +    ++ P  S     P  +G S +
Sbjct: 242 STPSS--STPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHS-S 298

Query: 274 GLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLE 333
           G     +    GTP+   L  Q LQ  +QAS    P+ + Q  P          +LQQL 
Sbjct: 299 GTSPMSSGVQSGTPITNDLFSQALQHALQAS--GQPSLQSQWQP----------QLQQLR 346

Query: 334 RMGFPTEQ-AVVALAAT-GRVEGAVSLLVGG 362
            MG   ++ ++ AL AT G ++ A+ L+  G
Sbjct: 347 DMGIQDDELSLRALQATGGDIQAALELIFAG 377


>gi|7706117 solute carrier family 15, member 3 [Homo sapiens]
          Length = 581

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 62  ALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLAL-ASGLLAVLLAGLGLSSAAGSCG 120
           AL  L  S LL P  GW  + +LG  R +  S LL L ASGLL       G SS    CG
Sbjct: 76  ALVFLGASYLLAPVGGWLADVYLGRYRAVALSLLLYLAASGLLPATAFPDGRSS---FCG 132

Query: 121 YMPVHLAMLAGEGHRPRRPRGALPPWLSPWLLLAL 155
            MP   + L         PR +  P+ +P L   L
Sbjct: 133 EMPA--SPLGPACPSAGCPRSSPSPYCAPVLYAGL 165


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 71/258 (27%), Positives = 91/258 (35%), Gaps = 51/258 (19%)

Query: 120  GYMPVHLAMLAGEGHRPRRPR---------GALPPWLSPWLLLAL----------TPLLS 160
            G  P H A+  G    P R R         GALP    P +   +            LL+
Sbjct: 6879 GESPEHGALAPGSRRHPARRRHLLKGGYIAGALPGLREPLMEHRVLEEEAAREEQATLLA 6938

Query: 161  SEPPFLQLLCGLLAGLAYAAGAFRWLE--------PSERRLQVLQEGVLCRTLAGCWPLR 212
              P F   L    +G   A G    LE        PS       Q   L    +G  P+R
Sbjct: 6939 KAPSFETALRLPASGTHLAPGHSHSLEHDSPSTPRPSSEACGEAQR--LPSAPSGGAPIR 6996

Query: 213  LLATPGSLAELPVT--HPAGVRPPIPGP--------PYVASPDLWSHWEDSALPPPSLRP 262
             +  P    +LP T  HP   +P  P P        P+   P   S  ++   P P++ P
Sbjct: 6997 DMGHPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAPF-CHPKQGSAPQEGCSPHPAVAP 7055

Query: 263  VQPTW--EGS-SEAGL----DWAGASFSPGTPMWAA--LDEQMLQEGIQ--ASLLDGPAQ 311
              P     GS  EA L     + G   +P  P  A+  LD +M    I        GP  
Sbjct: 7056 CPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKASPPLDSKMGPGDISLPGRPKPGPCS 7115

Query: 312  EPQSAPWLSKSSVSSLRL 329
             P SA   S S VSSLR+
Sbjct: 7116 SPGSASQASSSQVSSLRV 7133


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 11/96 (11%)

Query: 228 PAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDWAGASFSPGTP 287
           P G+RP    P  V  P  W+     AL PP   P Q +  G+  A   W  A   PG P
Sbjct: 299 PQGIRPQFTAPTQVPVPPGWNQLPSGALQPP---PAQGSL-GTMTANQGWKKAPL-PG-P 352

Query: 288 MWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSS 323
           M     +Q LQ     + +  P+  P   P+ S+ +
Sbjct: 353 M-----QQQLQARPSLATVQTPSHPPPPYPFGSQQA 383


>gi|148539835 dystroglycan 1 preproprotein [Homo sapiens]
          Length = 895

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 9/67 (13%)

Query: 210 PLRLLATPGSLAELPVTHPAG--VRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTW 267
           P R++ TP S A  P T      VR P+PG P V           + +  P+L P+QPT 
Sbjct: 335 PSRIVPTPTSPAIAPPTETMAPPVRDPVPGKPTVTI-----RTRGAIIQTPTLGPIQPT- 388

Query: 268 EGSSEAG 274
              SEAG
Sbjct: 389 -RVSEAG 394


>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
          Length = 961

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 52/204 (25%), Positives = 71/204 (34%), Gaps = 45/204 (22%)

Query: 210 PLRLLATPGSLAELPVTHPA------GVRPPIPGPP-YVASPDLWSHWEDSALPPPSLRP 262
           P RL + PG   E P   P+      G +P +P  P Y+  P +    E   +PPP  RP
Sbjct: 130 PQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPLEP--IPPPPSRP 187

Query: 263 VQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKS 322
           +    +     GL    A  SP +   ++L E+  +E +  +  D P   P   P     
Sbjct: 188 LPA--DPRVAKGLA-PRAEASPSSAAVSSLIEKFEREPVIVAS-DRPVPGPSPGP----- 238

Query: 323 SVSSLRLQQLERMGFPTEQAVVALAATGRVEGAVSLLVGG-------------------- 362
               + L Q      PT Q  V     G     + LL  G                    
Sbjct: 239 -PEPVMLPQ------PTSQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSP 291

Query: 363 QVGTETLVTHGKGGPAHSEGPGPP 386
               ET      G P+HS  PGPP
Sbjct: 292 SNSEETCFVSDDGPPSHSLCPGPP 315


>gi|94818879 rhomboid domain containing 2 isoform b [Homo sapiens]
          Length = 223

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 23/158 (14%)

Query: 143 LPPWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAAGAFRWLEPSER---------RL 193
           +P  L PWLLL  + L+  +  FL  +CGL  GLAY       ++ SER           
Sbjct: 21  VPSVLVPWLLLGASWLIP-QTSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPF 79

Query: 194 QVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPYVASPDLWSHWEDS 253
            +++   + + ++G    R  A    L  +P ++P     P   P +  S    +  +  
Sbjct: 80  SLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKL 139

Query: 254 ALPP-------PSLRPVQPTWEGSSEAGLDWAGASFSP 284
           A  P       P+L P QP       +GL +    F P
Sbjct: 140 ASWPSCTPGHMPTLPPYQPA------SGLCYVQNHFGP 171


>gi|19924103 synapsin II isoform IIa [Homo sapiens]
          Length = 582

 Score = 33.1 bits (74), Expect = 0.43
 Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 212 RLLATPGSLAELP------VTHPAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQP 265
           R L+    +A LP      +  P   +PP P PP   +    S    +A P P  RP   
Sbjct: 7   RRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASA-SAAPPTASPGPERRPPPA 65

Query: 266 TWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSA 316
           +      A     G+SF      +++L + + Q    A L+D PA  P +A
Sbjct: 66  SAPAPQPAPTPSVGSSF------FSSLSQAVKQTAASAGLVDAPAPAPAAA 110


>gi|19924101 synapsin II isoform IIb [Homo sapiens]
          Length = 478

 Score = 33.1 bits (74), Expect = 0.43
 Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 212 RLLATPGSLAELP------VTHPAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQP 265
           R L+    +A LP      +  P   +PP P PP   +    S    +A P P  RP   
Sbjct: 7   RRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASA-SAAPPTASPGPERRPPPA 65

Query: 266 TWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSA 316
           +      A     G+SF      +++L + + Q    A L+D PA  P +A
Sbjct: 66  SAPAPQPAPTPSVGSSF------FSSLSQAVKQTAASAGLVDAPAPAPAAA 110


>gi|119220575 mediator complex subunit 24 isoform 2 [Homo sapiens]
          Length = 976

 Score = 33.1 bits (74), Expect = 0.43
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 4/76 (5%)

Query: 289 WAALDEQMLQEGIQASLLDGPAQEPQSAPW----LSKSSVSSLRLQQLERMGFPTEQAVV 344
           W A++  +L+ G   + L  P    Q+        S  ++ S+  +Q+ + GFPT  AV+
Sbjct: 176 WTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVI 235

Query: 345 ALAATGRVEGAVSLLV 360
            L  T  + G    LV
Sbjct: 236 LLEGTMNLTGETQSLV 251


>gi|41281496 mediator complex subunit 24 isoform 1 [Homo sapiens]
          Length = 989

 Score = 33.1 bits (74), Expect = 0.43
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 4/76 (5%)

Query: 289 WAALDEQMLQEGIQASLLDGPAQEPQSAPW----LSKSSVSSLRLQQLERMGFPTEQAVV 344
           W A++  +L+ G   + L  P    Q+        S  ++ S+  +Q+ + GFPT  AV+
Sbjct: 189 WTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVI 248

Query: 345 ALAATGRVEGAVSLLV 360
            L  T  + G    LV
Sbjct: 249 LLEGTMNLTGETQSLV 264


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 15/32 (46%), Positives = 18/32 (56%)

Query: 228 PAGVRPPIPGPPYVASPDLWSHWEDSALPPPS 259
           PA   PP P PP++ SP L    +  A PPPS
Sbjct: 271 PASYTPPPPPPPFLNSPPLGPGLQPLAPPPPS 302


>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
          Length = 977

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 54/234 (23%), Positives = 86/234 (36%), Gaps = 18/234 (7%)

Query: 112 LSSAAGSCGYM-PVHLAMLAGEGHRPRRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLC 170
           LS  A +C +M PV         H   +    + P   P +     P ++ +PP   LL 
Sbjct: 677 LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLD 736

Query: 171 GLLAGLAYAAGAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAG 230
           GL+ G A +AG      P   RLQ     +  +  +      +  TPG           G
Sbjct: 737 GLVNGAASSAGI-----PEPPRLQGRGGELFAKRQSRADRYVVEGTPGP--------GLG 783

Query: 231 VRPPIPGPPYVASPDLWSHWEDSALPPP-SLRPVQPTWEGSSEAGLDWAGASFSPGTPMW 289
            RP  P P   + P  W +  +   PPP +  P+   +   +   L  A +     TP  
Sbjct: 784 PRPRSPSPT-PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQ 842

Query: 290 A--ALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQ 341
              ALD    Q     + +    + P +   ++  S  + R+Q++ R   P  Q
Sbjct: 843 GIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 896


>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
          Length = 753

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 54/234 (23%), Positives = 86/234 (36%), Gaps = 18/234 (7%)

Query: 112 LSSAAGSCGYM-PVHLAMLAGEGHRPRRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLC 170
           LS  A +C +M PV         H   +    + P   P +     P ++ +PP   LL 
Sbjct: 453 LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLD 512

Query: 171 GLLAGLAYAAGAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAG 230
           GL+ G A +AG      P   RLQ     +  +  +      +  TPG           G
Sbjct: 513 GLVNGAASSAGI-----PEPPRLQGRGGELFAKRQSRADRYVVEGTPGP--------GLG 559

Query: 231 VRPPIPGPPYVASPDLWSHWEDSALPPP-SLRPVQPTWEGSSEAGLDWAGASFSPGTPMW 289
            RP  P P   + P  W +  +   PPP +  P+   +   +   L  A +     TP  
Sbjct: 560 PRPRSPSPT-PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQ 618

Query: 290 A--ALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQ 341
              ALD    Q     + +    + P +   ++  S  + R+Q++ R   P  Q
Sbjct: 619 GIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 672


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 46/184 (25%), Positives = 67/184 (36%), Gaps = 15/184 (8%)

Query: 213 LLATPGSLAELPVTHPAGVRP---PIPGPPYVASPDLWSHWEDSALP-PPSLRPVQPTWE 268
           L AT   LAE+P++          P  GP    S +   + E+   P P +   +  T  
Sbjct: 357 LAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTE---NPEEGVTPGPDNEERLAATAA 413

Query: 269 GSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLR 328
           G +EA     G   + G      LD  M  + +      GP+ E       + + VS   
Sbjct: 414 GEAEALASMPGEVEASGVAP-GELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLST 472

Query: 329 LQQLERMGFPTEQAVVALAATGRVEGAVSLLVGGQ------VGTETLVTHGKGGPAHSEG 382
            +  E  G PT+  +  L AT   E AV+   G +         E L+T G         
Sbjct: 473 FEDEEASGVPTD-GLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPP 531

Query: 383 PGPP 386
            GPP
Sbjct: 532 DGPP 535


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 22/127 (17%)

Query: 197 QEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPYVASPDLWSHWEDSALP 256
           Q  + C    GC P      PG+     V    G+   +P PP           ED +  
Sbjct: 120 QSALECHPERGCVP-----EPGAA----VAASKGLPQQLPAPPD----------EDDSAA 160

Query: 257 PPSLRPVQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSA 316
           P +L  + PT+ G S    D         T     L +Q  QE +      G A+E   A
Sbjct: 161 PSTLSLLGPTFPGLSSCSADLKDILSEAST---MQLLQQQQQEAVSEGSSSGRAREASGA 217

Query: 317 PWLSKSS 323
           P  SK +
Sbjct: 218 PTSSKDN 224


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
            sapiens]
          Length = 2113

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 12/77 (15%)

Query: 186  LEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPYVASPD 245
            L+P+ + L +   G          P R LA P          PAG  PP PGP     P 
Sbjct: 2006 LDPASKSLGLPHPGAPAAASTATLPQRTLAMPAP--------PAGTAPPAPGPTPAEPPT 2057

Query: 246  LWSHWEDSALPPPSLRP 262
              S    +A P PS  P
Sbjct: 2058 APS----AAPPAPSTEP 2070


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 43/144 (29%), Positives = 61/144 (42%), Gaps = 22/144 (15%)

Query: 228 PAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQ----PTWEGSSEAGLDWAGASFS 283
           P G +  +   P V +P      + +  P PS  P Q       EG+  A    + AS  
Sbjct: 68  PGGQKQYVTELPAVPAPS-----QPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS-- 120

Query: 284 PG-TPMWAALDEQMLQE--GIQASLLDGPAQEPQSAPWLSKSSVSSLRLQ--QLERMGFP 338
           PG T     +  Q++Q+  G Q  LL       Q++       VS L+L   Q+ +   P
Sbjct: 121 PGSTASQTGVPTQVVQQVQGTQQRLL------VQTSVQAKPGHVSPLQLTNIQVPQQALP 174

Query: 339 TEQAVVALAATGRVEGAVSLLVGG 362
           T++ VV  AA G   G VSL V G
Sbjct: 175 TQRLVVQSAAPGSKGGQVSLTVHG 198


>gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchange
           factor 4 [Homo sapiens]
          Length = 368

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 13/68 (19%)

Query: 224 PVTHPAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDW-----A 278
           P THPA   PP P  P   SP LW       L P  +R  Q   E S +   D      +
Sbjct: 191 PWTHPAAAAPPPPAQP---SPSLWLE-----LGPACVRAQQCPSESSGQTSGDLGTSSSS 242

Query: 279 GASFSPGT 286
            A  SPG+
Sbjct: 243 SAGLSPGS 250


>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
            sapiens]
          Length = 1726

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 44/170 (25%), Positives = 65/170 (38%), Gaps = 31/170 (18%)

Query: 236  PGPPYVASPDLWSHWEDSALPPPSLRPVQPTW------------EGSSEAGLDWAGASFS 283
            P  P VA     +    SAL  P+ + +Q  W            +   E G  W  A+  
Sbjct: 845  PAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQ 904

Query: 284  PGTPM---WAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTE 340
              T     W    ++ LQ+G++ S         Q   W     + S  ++QL  MGFP E
Sbjct: 905  ESTSSCSSWGNAPKKGLQKGMKTS-------GKQDEAW-----IMSRLIKQLTDMGFPRE 952

Query: 341  QAVVALAATG-RVEGAVSLLVGGQVGTETL---VTHGKGGPAHSEGPGPP 386
             A  AL +    ++ A+S L+  +V  +     VT   G  A   G  PP
Sbjct: 953  PAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPP 1002


>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
            sapiens]
          Length = 1690

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 44/170 (25%), Positives = 65/170 (38%), Gaps = 31/170 (18%)

Query: 236  PGPPYVASPDLWSHWEDSALPPPSLRPVQPTW------------EGSSEAGLDWAGASFS 283
            P  P VA     +    SAL  P+ + +Q  W            +   E G  W  A+  
Sbjct: 848  PAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQ 907

Query: 284  PGTPM---WAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTE 340
              T     W    ++ LQ+G++ S         Q   W     + S  ++QL  MGFP E
Sbjct: 908  ESTSSCSSWGNAPKKGLQKGMKTS-------GKQDEAW-----IMSRLIKQLTDMGFPRE 955

Query: 341  QAVVALAATG-RVEGAVSLLVGGQVGTETL---VTHGKGGPAHSEGPGPP 386
             A  AL +    ++ A+S L+  +V  +     VT   G  A   G  PP
Sbjct: 956  PAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPP 1005


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 4/48 (8%)

Query: 228 PAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGL 275
           P G+RPP+ GPP    P          +PPP +RP  P   G    G+
Sbjct: 192 PPGMRPPM-GPPMGIPP---GRGTPMGMPPPGMRPPPPGMRGPPPPGM 235


>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
          Length = 1164

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 28/108 (25%), Positives = 39/108 (36%), Gaps = 12/108 (11%)

Query: 217 PGSLAELPVTHPAGVRPPIPGPPYVASP-----------DLWSHWEDSALPPPSLRPVQP 265
           P     LP+       PP+P PP +  P            L     DS+  P   + V+ 
Sbjct: 570 PAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKRKTVKL 629

Query: 266 TWEGSSEAGLDWAGAS-FSPGTPMWAALDEQMLQEGIQASLLDGPAQE 312
            W     AG     AS F P   +WA+LD   +       L +  A+E
Sbjct: 630 FWRELKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKE 677


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,838,627
Number of Sequences: 37866
Number of extensions: 1032431
Number of successful extensions: 4238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 4112
Number of HSP's gapped (non-prelim): 253
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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