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Search of human proteins with 167466201
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466201 WAS protein family homolog 1 [Homo sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466201 WAS protein family homolog 1 [Homo sapiens] 923 0.0
gi|239743666 PREDICTED: hypothetical protein XP_002342940 isofor... 903 0.0
gi|239743664 PREDICTED: hypothetical protein XP_002342939 isofor... 897 0.0
gi|110431370 espin [Homo sapiens] 62 1e-09
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 55 1e-07
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 2e-07
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 2e-07
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 2e-07
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 54 2e-07
gi|33356148 formin-like 1 [Homo sapiens] 54 4e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 52 9e-07
gi|7706687 Enah/Vasp-like [Homo sapiens] 52 1e-06
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 51 3e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 51 3e-06
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 50 3e-06
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 50 4e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 50 6e-06
gi|153792074 proline rich 12 [Homo sapiens] 50 6e-06
gi|157168329 formin 1 [Homo sapiens] 49 1e-05
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 49 1e-05
gi|52485606 formin-like 2 [Homo sapiens] 49 1e-05
gi|11386183 WAS protein family, member 2 [Homo sapiens] 49 1e-05
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 49 1e-05
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 49 1e-05
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 49 1e-05
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 48 2e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens] 48 2e-05
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 48 2e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 47 3e-05
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 46 6e-05
>gi|167466201 WAS protein family homolog 1 [Homo sapiens]
Length = 465
Score = 923 bits (2385), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60
MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS
Sbjct: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60
Query: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120
QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR
Sbjct: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120
Query: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180
HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE
Sbjct: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180
Query: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240
NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ
Sbjct: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240
Query: 241 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300
VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV
Sbjct: 241 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300
Query: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360
LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG
Sbjct: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360
Query: 361 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR 420
GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR
Sbjct: 361 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR 420
Query: 421 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465
KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES
Sbjct: 421 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465
>gi|239743666 PREDICTED: hypothetical protein XP_002342940 isoform 2
[Homo sapiens]
Length = 465
Score = 903 bits (2333), Expect = 0.0
Identities = 455/465 (97%), Positives = 459/465 (98%)
Query: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60
MTPVRMQHSLAGQTYAVP IQPDLRREEAVQQMADALQYLQKVSGDIFSRISQ+VEQSRS
Sbjct: 1 MTPVRMQHSLAGQTYAVPFIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRS 60
Query: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120
QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAP RLQEYGSIFTGAQDPGLQRRPR
Sbjct: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPGRLQEYGSIFTGAQDPGLQRRPR 120
Query: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180
HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE
Sbjct: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180
Query: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240
NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ
Sbjct: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240
Query: 241 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300
VPEI VPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV
Sbjct: 241 VPEIHVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300
Query: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360
LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG
Sbjct: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360
Query: 361 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR 420
G ATLLESIRQAGGIGKAKLRS+KERKLEK++QKEQEQVRATSQGG LMSDLFNKLVMRR
Sbjct: 361 GWATLLESIRQAGGIGKAKLRSMKERKLEKQQQKEQEQVRATSQGGHLMSDLFNKLVMRR 420
Query: 421 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465
KGISGKGPGAGEGPGGAF RVSDSIPPLPPPQQPQAEEDEDDWES
Sbjct: 421 KGISGKGPGAGEGPGGAFVRVSDSIPPLPPPQQPQAEEDEDDWES 465
>gi|239743664 PREDICTED: hypothetical protein XP_002342939 isoform 1
[Homo sapiens]
Length = 482
Score = 897 bits (2319), Expect = 0.0
Identities = 455/468 (97%), Positives = 459/468 (98%), Gaps = 3/468 (0%)
Query: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60
MTPVRMQHSLAGQTYAVP IQPDLRREEAVQQMADALQYLQKVSGDIFSRISQ+VEQSRS
Sbjct: 15 MTPVRMQHSLAGQTYAVPFIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRS 74
Query: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120
QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAP RLQEYGSIFTGAQDPGLQRRPR
Sbjct: 75 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPGRLQEYGSIFTGAQDPGLQRRPR 134
Query: 121 HRIQSKHRPLDERALQ---EKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFN 177
HRIQSKHRPLDERALQ EKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFN
Sbjct: 135 HRIQSKHRPLDERALQPSQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFN 194
Query: 178 TTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPD 237
TTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPD
Sbjct: 195 TTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPD 254
Query: 238 LGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQ 297
LGQVPEI VPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQ
Sbjct: 255 LGQVPEIHVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQ 314
Query: 298 DGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 357
DGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD
Sbjct: 315 DGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 374
Query: 358 PSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLV 417
PSGG ATLLESIRQAGGIGKAKLRS+KERKLEK++QKEQEQVRATSQGG LMSDLFNKLV
Sbjct: 375 PSGGWATLLESIRQAGGIGKAKLRSMKERKLEKQQQKEQEQVRATSQGGHLMSDLFNKLV 434
Query: 418 MRRKGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465
MRRKGISGKGPGAGEGPGGAF RVSDSIPPLPPPQQPQAEEDEDDWES
Sbjct: 435 MRRKGISGKGPGAGEGPGGAFVRVSDSIPPLPPPQQPQAEEDEDDWES 482
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 62.0 bits (149), Expect = 1e-09
Identities = 38/99 (38%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPV 331
PSAP LP H V D + PPPPPPPPPP PE +S PP PP
Sbjct: 567 PSAPPQAALLPGNH--VPNGCAADPKASRELPPPPPPPPPPLPEAASSPPPAPPLPLESA 624
Query: 332 GQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIR 370
G G Q SSSS + ++ P+G + LL I+
Sbjct: 625 GPGCGQRRSSSSTGST---KSFNMMSPTGDNSELLAEIK 660
Score = 37.7 bits (86), Expect = 0.022
Identities = 20/41 (48%), Positives = 21/41 (51%), Gaps = 4/41 (9%)
Query: 299 GVLTPPPPPP----PPPPAPEVLASAPPLPPSTAAPVGQGA 335
G TPPPPPP PPPP L PP P+ PVG A
Sbjct: 426 GKPTPPPPPPSFPPPPPPPGTQLPPPPPGYPAPKPPVGPQA 466
Score = 34.7 bits (78), Expect = 0.19
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 4/42 (9%)
Query: 293 KVDLQDGVLTPPPPPPP----PPPAPEVLASAPPLPPSTAAP 330
++ L G + P PPPP PPP P PP PP AP
Sbjct: 417 ELGLPRGTIGKPTPPPPPPSFPPPPPPPGTQLPPPPPGYPAP 458
Score = 32.3 bits (72), Expect = 0.94
Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 303 PPPPPP---PPPPAPEVLASAPPLPPSTA 328
PPPPPP PPP P A PP+ P A
Sbjct: 439 PPPPPPGTQLPPPPPGYPAPKPPVGPQAA 467
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 28/102 (27%)
Query: 301 LTPPPPPPPPPPA--PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDP 358
L+P P PP P + S P+PP+T AP G + D + + QG P
Sbjct: 699 LSPVRSPTPPAAGFQPLLNGSLVPVPPTTPAP---GVQLDVEALIPTHDEQGRP------ 749
Query: 359 SGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVR 400
I + K R V RK++ K Q+E+EQ R
Sbjct: 750 ----------------IPEWK-RQVMVRKMQLKMQEEEEQRR 774
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/195 (28%), Positives = 75/195 (38%), Gaps = 28/195 (14%)
Query: 271 APSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAP 330
AP P T LP P PPP PPPPPPAP SAPP P P
Sbjct: 279 APKVPPTPEPLPLSTPSAGTPQS--------QPPPLPPPPPPAP---GSAPPALPPEGPP 327
Query: 331 VGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGG----------IGKAKL 380
+ + QD + +S + G P+ AT + GG +G+A
Sbjct: 328 --EDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAA 385
Query: 381 RSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISG--KGP--GAGEGPGG 436
+R L + +EQ+ + + D+ +L++R KGP GAGEG
Sbjct: 386 PGNGQRSLVGSEGLSKEQLEHRERSLQTLRDI-ERLLLRSGETEPFLKGPPGGAGEGGPP 444
Query: 437 AFARVSDSIPPLPPP 451
A A PP PP
Sbjct: 445 AQAPPPPQQPPTAPP 459
Score = 53.1 bits (126), Expect = 5e-07
Identities = 48/177 (27%), Positives = 69/177 (38%), Gaps = 21/177 (11%)
Query: 290 EPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQ 349
EPL + PPP PPP P SAPP P P + + QD + +S +
Sbjct: 287 EPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPP--EDSSQDLAPNSVGAAST 344
Query: 350 GAPREVVDPSGGRATLLESIRQAGG----------IGKAKLRSVKERKLEKKKQKEQEQV 399
G P+ AT + GG +G+A +R L + +EQ+
Sbjct: 345 GGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQL 404
Query: 400 RATSQGGDLMSDLFNKLVMRRKGISG--KGPGAGEGPGGAFARVSDSIPPLPPPQQP 454
+ + D+ +L++R KGP G G GG A+ PPPQQP
Sbjct: 405 EHRERSLQTLRDI-ERLLLRSGETEPFLKGPPGGAGEGGPPAQAP------PPPQQP 454
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%)
Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305
DL +S LG + P+ PG +P +P F + + L+ PPP
Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 655
Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363
PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA
Sbjct: 656 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 714
Query: 364 TLLESI 369
ESI
Sbjct: 715 GSSESI 720
Score = 33.1 bits (74), Expect = 0.55
Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%)
Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347
P +++ PPP P PPPA P V+ + + PV S +
Sbjct: 409 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 464
Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404
V AP + P G TL + Q G A R V R + + V T Q
Sbjct: 465 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 521
Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446
G L +S L +L+M+ ++ PG P A A S
Sbjct: 522 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 581
Query: 447 ---PLPPPQQPQ 455
P PP PQ
Sbjct: 582 PGGPAQPPPTPQ 593
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314
P P PE ++ +EP++ + Q+ LTP P P P PAP
Sbjct: 198 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 257
Query: 315 EVLASAPPLP 324
E A P P
Sbjct: 258 ETNAPNHPSP 267
Score = 29.6 bits (65), Expect = 6.1
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352
PPP P A APP P A+ V + +SS+ +P AP
Sbjct: 388 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428
Score = 29.3 bits (64), Expect = 7.9
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%)
Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350
PPP PP P P L+S APP P A V + A + + P+ G
Sbjct: 196 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 252
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%)
Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305
DL +S LG + P+ PG +P +P F + + L+ PPP
Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 655
Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363
PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA
Sbjct: 656 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 714
Query: 364 TLLESI 369
ESI
Sbjct: 715 GSSESI 720
Score = 33.1 bits (74), Expect = 0.55
Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%)
Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347
P +++ PPP P PPPA P V+ + + PV S +
Sbjct: 409 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 464
Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404
V AP + P G TL + Q G A R V R + + V T Q
Sbjct: 465 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 521
Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446
G L +S L +L+M+ ++ PG P A A S
Sbjct: 522 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 581
Query: 447 ---PLPPPQQPQ 455
P PP PQ
Sbjct: 582 PGGPAQPPPTPQ 593
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314
P P PE ++ +EP++ + Q+ LTP P P P PAP
Sbjct: 198 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 257
Query: 315 EVLASAPPLP 324
E A P P
Sbjct: 258 ETNAPNHPSP 267
Score = 29.6 bits (65), Expect = 6.1
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352
PPP P A APP P A+ V + +SS+ +P AP
Sbjct: 388 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428
Score = 29.3 bits (64), Expect = 7.9
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%)
Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350
PPP PP P P L+S APP P A V + A + + P+ G
Sbjct: 196 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 252
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%)
Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305
DL +S LG + P+ PG +P +P F + + L+ PPP
Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 655
Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363
PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA
Sbjct: 656 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 714
Query: 364 TLLESI 369
ESI
Sbjct: 715 GSSESI 720
Score = 33.1 bits (74), Expect = 0.55
Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%)
Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347
P +++ PPP P PPPA P V+ + + PV S +
Sbjct: 409 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 464
Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404
V AP + P G TL + Q G A R V R + + V T Q
Sbjct: 465 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 521
Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446
G L +S L +L+M+ ++ PG P A A S
Sbjct: 522 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 581
Query: 447 ---PLPPPQQPQ 455
P PP PQ
Sbjct: 582 PGGPAQPPPTPQ 593
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314
P P PE ++ +EP++ + Q+ LTP P P P PAP
Sbjct: 198 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 257
Query: 315 EVLASAPPLP 324
E A P P
Sbjct: 258 ETNAPNHPSP 267
Score = 29.6 bits (65), Expect = 6.1
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352
PPP P A APP P A+ V + +SS+ +P AP
Sbjct: 388 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428
Score = 29.3 bits (64), Expect = 7.9
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%)
Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350
PPP PP P P L+S APP P A V + A + + P+ G
Sbjct: 196 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 252
>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
Length = 1132
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%)
Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305
DL +S LG + P+ PG +P +P F + + L+ PPP
Sbjct: 604 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 661
Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363
PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA
Sbjct: 662 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 720
Query: 364 TLLESI 369
ESI
Sbjct: 721 GSSESI 726
Score = 33.1 bits (74), Expect = 0.55
Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%)
Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347
P +++ PPP P PPPA P V+ + + PV S +
Sbjct: 415 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 470
Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404
V AP + P G TL + Q G A R V R + + V T Q
Sbjct: 471 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 527
Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446
G L +S L +L+M+ ++ PG P A A S
Sbjct: 528 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 587
Query: 447 ---PLPPPQQPQ 455
P PP PQ
Sbjct: 588 PGGPAQPPPTPQ 599
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314
P P PE ++ +EP++ + Q+ LTP P P P PAP
Sbjct: 204 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 263
Query: 315 EVLASAPPLP 324
E A P P
Sbjct: 264 ETNAPNHPSP 273
Score = 29.6 bits (65), Expect = 6.1
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352
PPP P A APP P A+ V + +SS+ +P AP
Sbjct: 394 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 434
Score = 29.3 bits (64), Expect = 7.9
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%)
Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350
PPP PP P P L+S APP P A V + A + + P+ G
Sbjct: 202 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 258
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 53.5 bits (127), Expect = 4e-07
Identities = 42/129 (32%), Positives = 51/129 (39%), Gaps = 23/129 (17%)
Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVA------ 289
P G P VP+ P + DL +A+ PG AP P +P LP+
Sbjct: 511 PSGGDAPTPGVPTGSP-----SPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQA 565
Query: 290 -------EPLKVDLQDGVLTPPPPPPPPPPAPE--VLASAPPLPPSTAAPVGQGARQDDS 340
EP G L PPPPPPPPPP + V PP PP P R+D
Sbjct: 566 PPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRD-- 623
Query: 341 SSSASPSVQ 349
S P V+
Sbjct: 624 -SELGPGVK 631
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 52.4 bits (124), Expect = 9e-07
Identities = 55/217 (25%), Positives = 78/217 (35%), Gaps = 35/217 (16%)
Query: 267 GPGIAPS-APGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPP----PPPPPA-PEVLASA 320
GP P+ G P P+ A P + V PPPPP PPPPPA P S
Sbjct: 298 GPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSG 357
Query: 321 PPLPPSTAAPVGQGARQDDSSSSASPSVQGAP-------REVVDPSGGRATLLESIRQAG 373
PP PP + VG A P P +V +G +A LL+ IR+
Sbjct: 358 PPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGA 417
Query: 374 GIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGK-----GP 428
+ K+ EQ + G D + D + + + G+ P
Sbjct: 418 QL----------------KKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTP 461
Query: 429 GAGEGPGGAFARVSDS-IPPLPPPQQPQAEEDEDDWE 464
G GA V + + + E+DE+D+E
Sbjct: 462 APTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFE 498
Score = 39.7 bits (91), Expect = 0.006
Identities = 21/35 (60%), Positives = 21/35 (60%), Gaps = 7/35 (20%)
Query: 303 PPPPPPP----PPPAPEVLASAPPLPPS---TAAP 330
PPPPPPP PPP P APP PPS TAAP
Sbjct: 288 PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP 322
Score = 37.0 bits (84), Expect = 0.038
Identities = 19/37 (51%), Positives = 21/37 (56%), Gaps = 8/37 (21%)
Query: 303 PPPPPP----PPPPAPEVLASAPPLPPSTAAPVGQGA 335
PPPPPP PPPP P S PP PP+ G+GA
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPAR----GRGA 309
>gi|7706687 Enah/Vasp-like [Homo sapiens]
Length = 418
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 28/150 (18%)
Query: 277 TIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGAR 336
T P LP H A V PPPPPPPP P P A+ PP PP A QG+
Sbjct: 162 TGPILPPGHPSSAASAPVSCSG----PPPPPPPPVPPPPTGATPPP-PPPLPAGGAQGSS 216
Query: 337 QDDSS-SSASPSVQGAPREVV----DPSGGRA----TLLESIRQAGGIG----------- 376
D+SS S + ++ GA V D SGG + + ++ R + G G
Sbjct: 217 HDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKL 276
Query: 377 ---KAKLRSVKERKLEKKKQKEQEQVRATS 403
+ K S ++ EKK+ + Q + +TS
Sbjct: 277 LAKRRKAASQSDKPAEKKEDESQMEDPSTS 306
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 50.8 bits (120), Expect = 3e-06
Identities = 42/132 (31%), Positives = 52/132 (39%), Gaps = 13/132 (9%)
Query: 293 KVDLQDGVLTPP---PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQ 349
+V G PP PPPPP PP P P LPPS GA + P+ Q
Sbjct: 155 RVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQ 214
Query: 350 GAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLM 409
G P GG A + A I AKLR V +++ + S GG LM
Sbjct: 215 G-------PGGGGA---GAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGLM 264
Query: 410 SDLFNKLVMRRK 421
++ L RRK
Sbjct: 265 EEMNAMLARRRK 276
Score = 30.0 bits (66), Expect = 4.7
Identities = 25/93 (26%), Positives = 32/93 (34%)
Query: 305 PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRAT 364
PPP PP PA + P AA + + S + AP+ SGG
Sbjct: 204 PPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGL 263
Query: 365 LLESIRQAGGIGKAKLRSVKERKLEKKKQKEQE 397
+ E KA K K E Q+E E
Sbjct: 264 MEEMNAMLARRRKATQVGEKTPKDESANQEEPE 296
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 50.8 bits (120), Expect = 3e-06
Identities = 46/156 (29%), Positives = 61/156 (39%), Gaps = 11/156 (7%)
Query: 303 PPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGR 362
PPPPPPP PP P L APP PP +A PV D+SS +G + D G
Sbjct: 4 PPPPPPPLPPPPPPL-GAPPPPPPSAPPV-----STDTSSLRRADPKGRSALLADIQQG- 56
Query: 363 ATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKL-VMRRK 421
T L + Q ++ S K E GDL + F L ++
Sbjct: 57 -TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115
Query: 422 GISGKGPGAGEGPGGAFARVSDSI--PPLPPPQQPQ 455
++G G G G R+ + PL PP P+
Sbjct: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPR 151
Score = 45.8 bits (107), Expect = 8e-05
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 18/93 (19%)
Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLG-PGIAPSAPGTIPELPTFHTEVAEPLKV 294
P VP P+ P P + L S+ + P ++P P T LP VA P+
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV----VAPPVPC 221
Query: 295 DLQDGVLTPPPPPPPPPPAPEVLASAPPLPPST 327
PPPPPPPPPP P PPLPP++
Sbjct: 222 -------APPPPPPPPPPTP------PPLPPAS 241
Score = 41.6 bits (96), Expect = 0.002
Identities = 40/131 (30%), Positives = 49/131 (37%), Gaps = 21/131 (16%)
Query: 235 VPDLGQVPEIDVPSYLPDLP--GIANDLMYSADLGPGIAPSAPGTIPELPT-----FHTE 287
VP P P P LP + +D L P P P +P LP E
Sbjct: 219 VPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE 278
Query: 288 VAEPLKVDLQDGVLTPPPPPPPPPP----APEVLASAPPLPPSTAAPVGQGARQDDSSSS 343
A P + D Q+ PP PPPP PP +P APPLP V +
Sbjct: 279 PASPAQ-DAQE----PPAPPPPLPPYASCSPRASLPAPPLP-----GVNSSSETPPPLPP 328
Query: 344 ASPSVQGAPRE 354
SPS Q P++
Sbjct: 329 KSPSFQAPPQK 339
Score = 39.3 bits (90), Expect = 0.008
Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 15/96 (15%)
Query: 239 GQVPEIDVPSYLPDLPG--IANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDL 296
GQ P PS P LP I+ L+ A G A G P A P
Sbjct: 123 GQGPGSRAPS--PRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPP----- 175
Query: 297 QDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVG 332
PP PPPPPPP P L S+ P+ +P G
Sbjct: 176 ------PPTPPPPPPPLPPPLPSSSPIKTPLVSPPG 205
Score = 30.0 bits (66), Expect = 4.7
Identities = 22/88 (25%), Positives = 31/88 (35%), Gaps = 9/88 (10%)
Query: 252 DLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPP- 310
+LP +A + + P P P +P + +P L + PP P PP
Sbjct: 211 NLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC 270
Query: 311 --------PPAPEVLASAPPLPPSTAAP 330
P +P A PP PP P
Sbjct: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPP 298
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 50.4 bits (119), Expect = 3e-06
Identities = 42/143 (29%), Positives = 60/143 (41%), Gaps = 25/143 (17%)
Query: 268 PGIAPS-APGTIPELPT-FHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPP 325
P ++P +P + P+LP T + PL V TPPPPPPPPPP P PP PP
Sbjct: 389 PYVSPRHSPWSSPKLPKKVQTVRSRPLSP-----VATPPPPPPPPPPPPPSSQRLPPPPP 443
Query: 326 STAAP----------VGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGI 375
P + + +Q +S+ A + Q + + L E
Sbjct: 444 PPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEI------- 496
Query: 376 GKAKLRSVKERKLEKKKQKEQEQ 398
K LRSV+E+K+E + Q
Sbjct: 497 -KNSLRSVQEKKMEDSSRPSTPQ 518
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 50.1 bits (118), Expect = 4e-06
Identities = 56/188 (29%), Positives = 76/188 (40%), Gaps = 24/188 (12%)
Query: 287 EVAEPLKVDLQDGVLT-----PPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQ-DDS 340
E + LK LQ V+ P P P P PP LP G Q D
Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
Query: 341 SSSASPSVQGAPREVVDPSGGR---ATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQE 397
S S SPS + +P PS G ++ E +GG K R ++E+K E K KEQ+
Sbjct: 306 SGSLSPSKK-SPVGKSPPSTGSTYGSSQKEESAASGGAAYTK-RYLEEQKTENGKDKEQK 363
Query: 398 QVRATSQGGDLMSDLFNKLVMRRKG-ISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQA 456
Q +K ++ KG S G G G+ +FA +DS P Q P+
Sbjct: 364 QTNT------------DKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKR 411
Query: 457 EEDEDDWE 464
+ DD+E
Sbjct: 412 YKLRDDFE 419
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 49.7 bits (117), Expect = 6e-06
Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 9/95 (9%)
Query: 246 VPSYLPDLPGIANDLMYSADLGPGIAPSAPGTI-PELPTFHTEVAEPLKVDLQDGVLTPP 304
VP LP LP S P IAP+ P T P +P EP ++ G L PP
Sbjct: 791 VPEGLPPLPPPPP----SGATPPPIAPTGPPTASPPVPAKE----EPEELPAAPGPLPPP 842
Query: 305 PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDD 339
PPPPPP P P L +P T G A ++D
Sbjct: 843 PPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEED 877
Score = 43.9 bits (102), Expect = 3e-04
Identities = 55/190 (28%), Positives = 76/190 (40%), Gaps = 40/190 (21%)
Query: 244 IDVPSYLPDLPGIANDLMYSADLGPGIAPSA--PGTIPELPTFHTEVAEP---------- 291
+ VP L LPG N S + P +APS P TIP TF V P
Sbjct: 717 VSVPPRL--LPGPENHRAGSNE-DPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEA 773
Query: 292 ------LKVDLQDGVLTPPPPPPPPPPAPEVLASAPPL----PPSTAAPVGQGARQDDSS 341
L+ D D V+ P PP PP P A+ PP+ PP+ + PV A+++
Sbjct: 774 SDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPV--PAKEEPEE 831
Query: 342 SSASPSVQGAPREVVDPSGGRATL----LESIRQAGGIGKAKL---------RSVKERKL 388
A+P P P G TL L GG G L S E +
Sbjct: 832 LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEE 891
Query: 389 EKKKQKEQEQ 398
E+++++E+E+
Sbjct: 892 EEEEEEEEEE 901
Score = 32.3 bits (72), Expect = 0.94
Identities = 20/60 (33%), Positives = 21/60 (35%), Gaps = 7/60 (11%)
Query: 299 GVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDP 358
G P P P PPP AP + P PP VG S SA P P P
Sbjct: 642 GPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVG-------SMPSAGPMPSAGPMPSAGP 694
Score = 29.6 bits (65), Expect = 6.1
Identities = 13/56 (23%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 295 DLQDGVLTPPPPPP--PPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSV 348
++++G PP PP PPP +P + P P V + +++ + +P++
Sbjct: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 49.7 bits (117), Expect = 6e-06
Identities = 38/136 (27%), Positives = 51/136 (37%), Gaps = 10/136 (7%)
Query: 251 PDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEV---------AEPLKVDLQDGVL 301
P LPG+ + P + P T P PT + A P L
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTP 1493
Query: 302 TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGA-PREVVDPSG 360
+ PPPPP PPP P + S PP PP AAP+ + + S P + P +
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQE 1553
Query: 361 GRATLLESIRQAGGIG 376
A E+ +AG G
Sbjct: 1554 TAAVCGETDEEAGESG 1569
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/125 (29%), Positives = 49/125 (39%), Gaps = 26/125 (20%)
Query: 245 DVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPP 304
D+P LP P L P + AP P + EP +DG PP
Sbjct: 789 DLPLVLPPPP---------PQLLPSVLSHAPSPSPSASKVGVHLLEPAT---RDGAPQPP 836
Query: 305 PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRAT 364
PPPPPPP PP+P A + + A+PS + P E +DP G
Sbjct: 837 PPPPPPP---------PPMPLQLEAHL-----RSHGLEPAAPSPRLRPEESLDPPGAMQE 882
Query: 365 LLESI 369
LL ++
Sbjct: 883 LLGAL 887
Score = 46.2 bits (108), Expect = 6e-05
Identities = 35/88 (39%), Positives = 39/88 (44%), Gaps = 19/88 (21%)
Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGT------IPELPTFHTEVA 289
P G P P+Y P P Y G P PG PELP+ T A
Sbjct: 974 PKAGAGPPPGPPAYDPYGP-------YCPGRASGAGPETPGLGLDPNKPPELPS--TVNA 1024
Query: 290 EPLKVDLQDG---VLTPPPPPPPPPPAP 314
EPL + +Q G PPPPPPPPPPAP
Sbjct: 1025 EPLGL-IQSGPHQAAPPPPPPPPPPPAP 1051
Score = 32.7 bits (73), Expect = 0.72
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 19/115 (16%)
Query: 269 GIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPS-- 326
G AP P LP T + Q PPPPPPP A + S PS
Sbjct: 270 GAAPGPPPPERALPRQDTVIKH-----YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMG 324
Query: 327 -----TAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIG 376
+P+G G + S + PS G P + GRAT E+ AGG G
Sbjct: 325 HRANLACSPLGGG---EPSPGAGEPSKAG-PSGATAGASGRATGPEA---AGGGG 372
Score = 29.3 bits (64), Expect = 7.9
Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 23/156 (14%)
Query: 321 PPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG--GRATLLESIRQAG-GIG- 376
PPL P + P AR A+P+V P PSG G LE+ G G+G
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPP-----PSGAFGLGGALEAAESEGLGLGC 1359
Query: 377 ---KAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKL-VMRRKGISG-KGPGAG 431
+L +R LE ++ + ++ DL + + + + ++G K
Sbjct: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419
Query: 432 EGPGGAFARVSDSIPPLP---------PPQQPQAEE 458
+GP A A PPLP P+ P EE
Sbjct: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE 1455
Score = 29.3 bits (64), Expect = 7.9
Identities = 15/37 (40%), Positives = 15/37 (40%), Gaps = 5/37 (13%)
Query: 299 GVLTPPPPPPPPPPAPE-----VLASAPPLPPSTAAP 330
G PPP P PPP PE P P TA P
Sbjct: 1688 GSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMP 1724
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 48.9 bits (115), Expect = 1e-05
Identities = 43/168 (25%), Positives = 63/168 (37%), Gaps = 20/168 (11%)
Query: 198 KTHVMLGAETEEKLFDAPL-SISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPGI 256
KT + +T+ + F P S SK + Q VP+ ++ + ++ P+ D+
Sbjct: 575 KTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKL----NISSLSQLSPPNDHKDIHAA 630
Query: 257 ANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAE----PLKVDLQDGVLTPPPPPPPPPP 312
+ A P P +IP P + + P + G PPPPPPPPP
Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690
Query: 313 APEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360
P A PP PP P +S +P G P P G
Sbjct: 691 PPPSSAGPPPPPPPPPLP-----------NSPAPPNPGGPPPAPPPPG 727
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 48.5 bits (114), Expect = 1e-05
Identities = 42/158 (26%), Positives = 51/158 (32%), Gaps = 12/158 (7%)
Query: 299 GVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDP 358
G P PPPPPPPAP PP PP A P G G + P + P E D
Sbjct: 15 GATPAPGPPPPPPPAPP--QQQPPPPPPPAPPPGPG----PAPPQHPPRAEALPPEAADE 68
Query: 359 SGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVM 418
G R L G G S + + + + Q G +
Sbjct: 69 GGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVS---- 124
Query: 419 RRKGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQA 456
G G GPG A S+ P P+ QA
Sbjct: 125 --FSCRGAASGPAPGPGPAEEAGSEEAGPAGEPRGSQA 160
Score = 33.1 bits (74), Expect = 0.55
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 265 DLGPGIAPSAPGTI-PELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVL--ASAP 321
DL G+ + I E+ + E+ + ++ + G+ PPPPPP A L A+A
Sbjct: 677 DLNSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAM 736
Query: 322 PLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363
P A P+ P G+PR V P G A
Sbjct: 737 SFCPQVARPL------------VGPLALGSPRLVRRPPPGPA 766
Score = 29.3 bits (64), Expect = 7.9
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 26/96 (27%)
Query: 283 TFHTEVAEPLKVDLQDG----VLTPPPPPPP-------PPPAPEVLASAPPLPPST---- 327
+F +VA PL L G V PPP P P PPPA A A P P T
Sbjct: 737 SFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYG 796
Query: 328 ----------AAPVGQGARQDDSSSSASPSV-QGAP 352
A P + +R S++ PS+ GAP
Sbjct: 797 GLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAP 832
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 48.5 bits (114), Expect = 1e-05
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 256 IANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPE 315
+ ++++ +GP + ++ G +P P ++ + +Q+G +TPP PPPPPPP P
Sbjct: 504 MGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPET-VQNGPVTPPMPPPPPPPPPP 562
Query: 316 VLASAPPLPPSTAAPVGQ 333
PP PP P +
Sbjct: 563 PPPPPPPPPPPLPGPAAE 580
Score = 42.7 bits (99), Expect = 7e-04
Identities = 33/99 (33%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVD 295
P +G +P P LP ++D + GP P P P P
Sbjct: 516 PTMGAASSGPLPPPPPPLPP-SSDTPETVQNGPVTPPMPPPPPPPPPP------------ 562
Query: 296 LQDGVLTPPPPPPPPPPAPEVLAS---APPL-PPSTAAP 330
PPPPPPPPPP P A APPL PP +AP
Sbjct: 563 ------PPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAP 595
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/129 (31%), Positives = 54/129 (41%), Gaps = 23/129 (17%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPP--------PPPPPPPAPEVLASAPPL 323
P +P + P P F P L PPP PPPPPPP P PP
Sbjct: 349 PPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP----PGPPP 404
Query: 324 PPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSV 383
PP T A GQ A S + P + S R+ LL +IRQ +LR V
Sbjct: 405 PPFTGAD-GQPAIPPPLSDTTKPK-----SSLPAVSDARSDLLSAIRQG-----FQLRRV 453
Query: 384 KERKLEKKK 392
+E++ ++K+
Sbjct: 454 EEQREQEKR 462
Score = 40.8 bits (94), Expect = 0.003
Identities = 74/368 (20%), Positives = 118/368 (32%), Gaps = 74/368 (20%)
Query: 40 LQKVSGDIFSRISQRVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPER 99
L K + DIF + + S+V ++ E+V Q K+ ++ ++ + +
Sbjct: 43 LSKYAEDIFGELFTQANTFASRVSSLAERVDRLQVKVTQLDPKEEEVSL----------- 91
Query: 100 LQEYGSIFTGAQDPGLQRRPRHRIQS--KHRPLDERALQEK-LKDFPVCVSTKP-----E 151
G+ R R + + D +L L+ + C + P
Sbjct: 92 -------------QGINTRKAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPLNNLTP 138
Query: 152 PEDDAEEGLGGL--PSNISSVSSLLLFNTTENLYK------KYVFLDPLAGAVTKTHVML 203
DD +E L PS + + T+++ K K +P G V +
Sbjct: 139 YRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKT 198
Query: 204 GAETEEKLFDAPLSISKREQLEQQ--VPENYFYVPDLGQVPEIDVPSYLP---------- 251
E EK+ + +E+L P + +G V +D SY P
Sbjct: 199 RKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSP 258
Query: 252 -------DLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPP 304
+LP + Y D G + P + H A PL +PP
Sbjct: 259 SPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLG--------SPP 310
Query: 305 -------PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 357
PPP PPPP P ++ PP PP G S P P
Sbjct: 311 GPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPP 370
Query: 358 PSGGRATL 365
P+ TL
Sbjct: 371 PAADYPTL 378
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 17/184 (9%)
Query: 239 GQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQD 298
GQ+P + +P+ P P ++ A P + P+ P P PL
Sbjct: 758 GQLPPLLIPTD-PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQ 816
Query: 299 GVL-----TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPR 353
L T P P P PP ++++A P PP+ ++ + SSS+S S
Sbjct: 817 SPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSS------ 870
Query: 354 EVVDPSGGRATLLESIRQAGGIGKAKLR--SVKERKLEKKKQKEQEQVRATSQGGDLMSD 411
PS + + S+ +G +A L S K+ +LE + K +E+ ++ ++ ++ +
Sbjct: 871 ---SPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQE 927
Query: 412 LFNK 415
FNK
Sbjct: 928 TFNK 931
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 17/184 (9%)
Query: 239 GQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQD 298
GQ+P + +P+ P P ++ A P + P+ P P PL
Sbjct: 959 GQLPPLLIPTD-PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQ 1017
Query: 299 GVL-----TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPR 353
L T P P P PP ++++A P PP+ ++ + SSS+S S
Sbjct: 1018 SPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSS------ 1071
Query: 354 EVVDPSGGRATLLESIRQAGGIGKAKLR--SVKERKLEKKKQKEQEQVRATSQGGDLMSD 411
PS + + S+ +G +A L S K+ +LE + K +E+ ++ ++ ++ +
Sbjct: 1072 ---SPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQE 1128
Query: 412 LFNK 415
FNK
Sbjct: 1129 TFNK 1132
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 17/184 (9%)
Query: 239 GQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQD 298
GQ+P + +P+ P P ++ A P + P+ P P PL
Sbjct: 959 GQLPPLLIPTD-PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQ 1017
Query: 299 GVL-----TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPR 353
L T P P P PP ++++A P PP+ ++ + SSS+S S
Sbjct: 1018 SPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSS------ 1071
Query: 354 EVVDPSGGRATLLESIRQAGGIGKAKLR--SVKERKLEKKKQKEQEQVRATSQGGDLMSD 411
PS + + S+ +G +A L S K+ +LE + K +E+ ++ ++ ++ +
Sbjct: 1072 ---SPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQE 1128
Query: 412 LFNK 415
FNK
Sbjct: 1129 TFNK 1132
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/223 (27%), Positives = 84/223 (37%), Gaps = 13/223 (5%)
Query: 139 LKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTK 198
L D P +S P P D +PS S V SLL + V P
Sbjct: 146 LSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSP---PSDVPSPPSDVPSPP 202
Query: 199 THVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPE--IDVPSYLPDLPGI 256
+ V L ++ D PL +S VP VP L VP DVPS L +P
Sbjct: 203 SDVPLLSDVPSPPSDVPL-LSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSP 261
Query: 257 ANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPP--PPPPAP 314
+D+ +D+ P + P ++P+ + V P D+ + P PP P PP+
Sbjct: 262 PSDISPPSDV-PSLLSDVPSLPSDVPSLLSGVPSPPS-DVPSLLSDVPSPPSDVPSPPSD 319
Query: 315 EVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 357
L S P PPS V S S P + G P + D
Sbjct: 320 IPLLSGVPSPPS---DVPSPPSDVPSPPSDVPLLSGVPSPLSD 359
Score = 46.2 bits (108), Expect = 6e-05
Identities = 64/248 (25%), Positives = 88/248 (35%), Gaps = 34/248 (13%)
Query: 119 PRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNT 178
P + + S HRPL L S P P D L G+PS S VSS +
Sbjct: 95 PHYSLVSPHRPLVSPLL-----------SGVPSPPSDVPSLLSGVPSLPSDVSSPP--SD 141
Query: 179 TENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDL 238
+L L L+G + ++ D P S L VP VP
Sbjct: 142 VPSLLSDVPSL--LSGVPSPP-----SDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVPS- 193
Query: 239 GQVPEIDVPS------YLPDLPGIANDLMYSADLG--PGIAPSAPGTIPELPTFHTEVAE 290
P DVPS L D+P +D+ +D+ P PS P +P L + ++
Sbjct: 194 ---PPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSD 250
Query: 291 PLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQG 350
L GV +PP PP P +L+ P LP + + S V
Sbjct: 251 V--PSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPS 308
Query: 351 APREVVDP 358
P +V P
Sbjct: 309 PPSDVPSP 316
Score = 29.3 bits (64), Expect = 7.9
Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 20/74 (27%)
Query: 244 IDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTP 303
+DVPS L D+P + + + PS+P +P LP+ V + GV +
Sbjct: 396 LDVPSLLSDVPSLLSGV-----------PSSPSGVPSLPS---------GVPILSGVPSL 435
Query: 304 PPPPPPPPPAPEVL 317
P P P P L
Sbjct: 436 PSGVPSPSGVPITL 449
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 13/111 (11%)
Query: 264 ADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPL 323
A L P P+APGT+ + P F A P P P PP PAP A+APP
Sbjct: 223 AALLPLPKPAAPGTVIQTPPFVGAAAPP----------APAAPSPPAAPAPAAPAAAPPP 272
Query: 324 PPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGG 374
PP A + + +A+P+V P +GG A + A G
Sbjct: 273 PPPAPATLARPPGHPAGPPTAAPAV---PPPAAAQNGGSAGAAPAPAPAAG 320
Score = 38.1 bits (87), Expect = 0.017
Identities = 35/124 (28%), Positives = 42/124 (33%), Gaps = 43/124 (34%)
Query: 267 GPGIAP-----------------------------------SAPGTIPELPTFHTEVAEP 291
GPG A +APGT+ + P F A P
Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250
Query: 292 LKV----DLQDGVLTPPPPPPPPPPAPEVLASAP--PLPPSTAAPV--GQGARQDDSSSS 343
P PPPPPPAP LA P P P TAAP A Q+ S+
Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG 310
Query: 344 ASPS 347
A+P+
Sbjct: 311 AAPA 314
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/48 (50%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 302 TPPPPPPPPPPAPEVLASAPPLPPST-AAPVGQGARQDDSSSSASPSV 348
TP PPPPPPPP P L +APP P ST A P + + A PSV
Sbjct: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSV 2083
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 8/54 (14%)
Query: 285 HTEVAEPLKVDLQDGVLTPPPPPPPPPPA--------PEVLASAPPLPPSTAAP 330
H + PL+ + PPPPPPPP PA P + ASAPP+ T AP
Sbjct: 2025 HYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAP 2078
Score = 30.8 bits (68), Expect = 2.7
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%)
Query: 236 PDLGQVPEIDVPSYLPDLP--GIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLK 293
P+L +P VPS P LP G+ N ++ P A + P+ P + + +
Sbjct: 3149 PNLMGLPSTTVPS--PGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQ 3206
Query: 294 VDLQDGVLTPPPPPPPPPPAPEV 316
V PPPP PPP P++
Sbjct: 3207 VQQP-----PPPPAAQPPPTPQL 3224
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 47.4 bits (111), Expect = 3e-05
Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)
Query: 268 PGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVL-ASAPPLPPS 326
P + P AP P LP T PL V PP P PPPPPA E S PP+ P+
Sbjct: 404 PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPA 463
Query: 327 TAA------PVGQGARQDDSSSSASP------------SVQGAPREVVDPSGGRATLLES 368
T + P+ R + ++ A P + G P + + T L++
Sbjct: 464 TCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKN 523
Query: 369 IRQ 371
IRQ
Sbjct: 524 IRQ 526
Score = 46.2 bits (108), Expect = 6e-05
Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 2/112 (1%)
Query: 272 PSAPGTI-PELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAP 330
P P TI P PT T PL L + P PPPPPPP VL+S P PP A
Sbjct: 2218 PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIR 2277
Query: 331 VGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRS 382
V + + S A P + APR D T +GG + ++++
Sbjct: 2278 VKRVSTFSGRSPPAPPPYK-APRLDEDGEASEDTPQVPGLGSGGFSRVRMKT 2328
Score = 39.3 bits (90), Expect = 0.008
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
Query: 268 PGIAPSAPGTIPELPTFHTEVA-EP-LKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPP 325
P AP+ P T LP + EP + L PPPP PPPPPAP S PP P
Sbjct: 583 PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP----SPPPAPA 638
Query: 326 STA 328
+++
Sbjct: 639 TSS 641
Score = 38.9 bits (89), Expect = 0.010
Identities = 24/74 (32%), Positives = 29/74 (39%)
Query: 289 AEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSV 348
AE + L LTPP P PPPP P + PPL P PV A
Sbjct: 394 AEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQ 453
Query: 349 QGAPREVVDPSGGR 362
+ +P VV + R
Sbjct: 454 EESPPPVVPATCSR 467
Score = 34.3 bits (77), Expect = 0.25
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 14/70 (20%)
Query: 272 PSAPGTIPELPTFHTEVAEPLKV-DLQDGVLTPP-----------PPPPPPPPAPEVLAS 319
P P +P P T + P+ + + + +L P PPPPP PP P A
Sbjct: 574 PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP--AP 631
Query: 320 APPLPPSTAA 329
+PP P+T++
Sbjct: 632 SPPPAPATSS 641
Score = 33.5 bits (75), Expect = 0.42
Identities = 17/51 (33%), Positives = 23/51 (45%)
Query: 281 LPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPV 331
+P E A+ L +PPPP PPP +P PP PP + P+
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL 441
Score = 32.7 bits (73), Expect = 0.72
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 290 EPLKVDLQDGVLTPP---PPPPPPPPAPEVLASAPPLPPSTAAPVGQGAR 336
+P KV++ VL PP PP P PAP P PPST P+ + R
Sbjct: 553 KPPKVEVSP-VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR 601
Score = 32.7 bits (73), Expect = 0.72
Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 67/237 (28%)
Query: 272 PSAPGTIPELPTF-----HTEVAEPLKVDLQDGVLTPPP------PPPPPPPAPEVLASA 320
P AP T P T LK+ + VLTPPP P P PPPA + A
Sbjct: 634 PPAPATSSRRPLLLRAPQFTPSEAHLKI--YESVLTPPPLGAPEAPEPEPPPADDSPAEP 691
Query: 321 PP--------LPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD--------------- 357
P L APV + + S +P++ P+
Sbjct: 692 EPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQ 751
Query: 358 ------------PSGGRATLLESIRQAGGIGKAKLRSVKER----------KLEKKKQKE 395
PS + LE R A G+G L V+E+ +L K Q++
Sbjct: 752 ALPPPQPQLQPPPSPQQMPPLEKARIA-GVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQ 810
Query: 396 QEQVRAT---SQGGDLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIPPLP 449
Q++V A+ S GG + ++ K IS +GP E R S P P
Sbjct: 811 QQKVAASMPLSPGGQM-----EEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESP 862
Score = 32.3 bits (72), Expect = 0.94
Identities = 59/240 (24%), Positives = 85/240 (35%), Gaps = 45/240 (18%)
Query: 248 SYLPDLPGIANDLMYSADLGPGIAPSAPGT-----IPELPTFHTEVAEPLKVDLQDGVLT 302
++LP PG+ LGP P P T + +L ++A G
Sbjct: 2164 AWLPGAPGVR-----VLSLGPAPEPPKPATSKIILVNKLGQVFVKMA---------GEGE 2209
Query: 303 PPPPPPPPPPAPEVLASAPPLPPSTAAPVGQ--GARQDDSSSSASPSVQGAPREVVDPSG 360
P PPP PP P + +P P S P G G +P P +V SG
Sbjct: 2210 PVPPPVKQPPLPPTI--SPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSG 2267
Query: 361 GRATLLESIR-----QAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNK 415
+ ++IR G K +L++ + ++ T Q L S F++
Sbjct: 2268 PASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASED----TPQVPGLGSGGFSR 2323
Query: 416 LVMRRKGISG------KGPGAGEGPGGAFARVSDSIPPLP---PPQQPQAEED---EDDW 463
+ M+ + G G AGE G S + PLP PPQ P D E W
Sbjct: 2324 VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLL-PLPEDGPPQVPDGPPDLLLESQW 2382
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 270 IAPSAPGTIPELPTFHTEVAEPLKV---DLQDGVLTPPPPPPPPPPAPEVLASAPPLPPS 326
++P + P ++ +PL+ L L PP P PPP+P+ + PPL +
Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQM---PPLEKA 775
Query: 327 TAAPVG 332
A VG
Sbjct: 776 RIAGVG 781
Score = 30.8 bits (68), Expect = 2.7
Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 23/74 (31%)
Query: 272 PSAPGTIPEL-------PTFH-TEVAEPLKVDLQDGVLTPPPPPPP---PPPAP------ 314
PS P +PE PTF T + L P PPPPP PPPAP
Sbjct: 590 PSTPVPLPEKRRSILREPTFRWTSLTRELPPP------PPAPPPPPAPSPPPAPATSSRR 643
Query: 315 EVLASAPPLPPSTA 328
+L AP PS A
Sbjct: 644 PLLLRAPQFTPSEA 657
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 46.2 bits (108), Expect = 6e-05
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 270 IAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTA- 328
++P+ P P LP+ + L+ + TPPPP PPPPP P AP +PP A
Sbjct: 320 VSPTPPPPPPPLPSALS--TSSLRASMTS---TPPPPVPPPPPPPATALQAPAVPPPPAP 374
Query: 329 APVGQGARQDDSSSSASPSVQGAP 352
+ G A P VQ +P
Sbjct: 375 LQIAPGVLHPAPPPIAPPLVQPSP 398
Score = 45.8 bits (107), Expect = 8e-05
Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 24/171 (14%)
Query: 247 PSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPP 306
P+ L PG+ + + P + +P P T PL G+ PPPP
Sbjct: 372 PAPLQIAPGVLHPA--PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP 429
Query: 307 PPPPPPA---------------PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGA 351
PP PPP P L P P P+ + ++ P +
Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
Query: 352 PREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRAT 402
V+ S R+ LLE+IR+ +LR V+E++ ++ K + E AT
Sbjct: 490 TLPVI--SDARSVLLEAIRKG-----IQLRKVEEQREQEAKHERIENDVAT 533
Score = 35.8 bits (81), Expect = 0.085
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 11/42 (26%)
Query: 300 VLTPPPPPPPPPPAPEVLASA-----------PPLPPSTAAP 330
V P PPPPPPP P L+++ PP+PP P
Sbjct: 318 VFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPP 359
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,894,738
Number of Sequences: 37866
Number of extensions: 1487443
Number of successful extensions: 35631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 765
Number of HSP's successfully gapped in prelim test: 899
Number of HSP's that attempted gapping in prelim test: 14390
Number of HSP's gapped (non-prelim): 10515
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.