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Search of human proteins with 16554625
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16554625 WD repeat domain 10 isoform 4 [Homo sapiens]
(1131 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16554625 WD repeat domain 10 isoform 4 [Homo sapiens] 2306 0.0
gi|16554619 WD repeat domain 10 isoform 3 [Homo sapiens] 2276 0.0
gi|16554623 WD repeat domain 10 isoform 2 [Homo sapiens] 2228 0.0
gi|16554621 WD repeat domain 10 isoform 1 [Homo sapiens] 2127 0.0
gi|41146563 PREDICTED: hypothetical protein LOC653712 [Homo sapi... 184 3e-46
gi|169165594 PREDICTED: hypothetical LOC653712 [Homo sapiens] 183 7e-46
gi|88971034 PREDICTED: hypothetical LOC653712 [Homo sapiens] 183 7e-46
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 64 6e-10
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 64 6e-10
gi|55743151 WD repeat domain 19 [Homo sapiens] 57 1e-07
gi|46358428 selective LIM binding factor homolog [Homo sapiens] 54 8e-07
gi|223005862 echinoderm microtubule associated protein like 6 [H... 49 4e-05
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 44 9e-04
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 44 9e-04
gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog... 42 0.003
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 42 0.004
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 42 0.004
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 41 0.006
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 40 0.010
gi|21071067 TBP-associated factor 5 [Homo sapiens] 39 0.021
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 39 0.021
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 39 0.021
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 39 0.021
gi|46409657 WD repeat domain 56 [Homo sapiens] 38 0.048
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 38 0.062
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 38 0.062
gi|26665869 WD repeat domain 51B [Homo sapiens] 38 0.062
gi|16554629 WD repeat domain 5 [Homo sapiens] 37 0.081
gi|16554627 WD repeat domain 5 [Homo sapiens] 37 0.081
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 37 0.11
>gi|16554625 WD repeat domain 10 isoform 4 [Homo sapiens]
Length = 1131
Score = 2306 bits (5977), Expect = 0.0
Identities = 1131/1131 (100%), Positives = 1131/1131 (100%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDGLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERP 120
YAKDGLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERP
Sbjct: 61 YAKDGLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERP 120
Query: 121 GGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTK 180
GGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTK
Sbjct: 121 GGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTK 180
Query: 181 GEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLI 240
GEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLI
Sbjct: 181 GEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLI 240
Query: 241 FSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILI 300
FSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILI
Sbjct: 241 FSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILI 300
Query: 301 YELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMES 360
YELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMES
Sbjct: 301 YELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMES 360
Query: 361 LIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAV 420
LIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAV
Sbjct: 361 LIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAV 420
Query: 421 VDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQ 480
VDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQ
Sbjct: 421 VDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQ 480
Query: 481 GFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAM 540
GFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAM
Sbjct: 481 GFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAM 540
Query: 541 EALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAK 600
EALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAK
Sbjct: 541 EALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAK 600
Query: 601 LYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMY 660
LYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMY
Sbjct: 601 LYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMY 660
Query: 661 ISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKM 720
ISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKM
Sbjct: 661 ISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKM 720
Query: 721 GDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQ 780
GDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQ
Sbjct: 721 GDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQ 780
Query: 781 REAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCLDIAQADPAQKDTMLGKFYHFQRLAE 840
REAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCLDIAQADPAQKDTMLGKFYHFQRLAE
Sbjct: 781 REAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCLDIAQADPAQKDTMLGKFYHFQRLAE 840
Query: 841 LYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALG 900
LYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALG
Sbjct: 841 LYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALG 900
Query: 901 AYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNL 960
AYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNL
Sbjct: 901 AYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNL 960
Query: 961 GNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANN 1020
GNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANN
Sbjct: 961 GNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANN 1020
Query: 1021 SSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPL 1080
SSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPL
Sbjct: 1021 SSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPL 1080
Query: 1081 RWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1131
RWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP
Sbjct: 1081 RWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1131
>gi|16554619 WD repeat domain 10 isoform 3 [Homo sapiens]
Length = 1182
Score = 2276 bits (5898), Expect = 0.0
Identities = 1130/1183 (95%), Positives = 1130/1183 (95%), Gaps = 53/1183 (4%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDG----------------------------------------------------LWS 68
YAKDG LWS
Sbjct: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTHNDAIQCVSYNPITHQLASCSSSDFGLWS 120
Query: 69 PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIW 128
PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIW
Sbjct: 121 PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIW 180
Query: 129 SICWNPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGG 188
SICWNPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGG
Sbjct: 181 SICWNPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGG 240
Query: 189 SDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLY 248
SDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLY
Sbjct: 241 SDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLY 300
Query: 249 KDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDL 308
KDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDL
Sbjct: 301 KDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDL 360
Query: 309 SDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVI 368
SDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVI
Sbjct: 361 SDMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVI 420
Query: 369 GGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCL 428
GGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCL
Sbjct: 421 GGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCL 480
Query: 429 VYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNG 488
VYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNG
Sbjct: 481 VYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNG 540
Query: 489 SKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDF 548
SKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDF
Sbjct: 541 SKIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDF 600
Query: 549 ETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHE 608
ETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHE
Sbjct: 601 ETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHE 660
Query: 609 NLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVK 668
NLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVK
Sbjct: 661 NLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVK 720
Query: 669 AIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQ 728
AIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQ
Sbjct: 721 AIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQ 780
Query: 729 LHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLE 788
LHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLE
Sbjct: 781 LHVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLE 840
Query: 789 QLTNNAVAESRFNDAAYYYWMLSMQCLDIAQADPAQKDTMLGKFYHFQRLAELYHGYHAI 848
QLTNNAVAESRFNDAAYYYWMLSMQCLDIAQ DPAQKDTMLGKFYHFQRLAELYHGYHAI
Sbjct: 841 QLTNNAVAESRFNDAAYYYWMLSMQCLDIAQ-DPAQKDTMLGKFYHFQRLAELYHGYHAI 899
Query: 849 HRHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHA 908
HRHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHA
Sbjct: 900 HRHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHA 959
Query: 909 YDKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCR 968
YDKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCR
Sbjct: 960 YDKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCR 1019
Query: 969 QPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLV 1028
QPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLV
Sbjct: 1020 QPFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLV 1079
Query: 1029 ETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSL 1088
ETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSL
Sbjct: 1080 ETKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSL 1139
Query: 1089 LPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1131
LPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP
Sbjct: 1140 LPDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1182
>gi|16554623 WD repeat domain 10 isoform 2 [Homo sapiens]
Length = 1241
Score = 2228 bits (5773), Expect = 0.0
Identities = 1123/1242 (90%), Positives = 1125/1242 (90%), Gaps = 112/1242 (9%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDG----------------------------------------------------LWS 68
YAKDG LWS
Sbjct: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTHNDAIQCVSYNPITHQLASCSSSDFGLWS 120
Query: 69 PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPI- 127
PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPI
Sbjct: 121 PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIW 180
Query: 128 ---------WSICW---------------------------------------------- 132
W W
Sbjct: 181 SICWNPSSRWESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDD 240
Query: 133 ---NPSREERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGS 189
+ + EERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGS
Sbjct: 241 SPRDDNLEERNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGS 300
Query: 190 DKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYK 249
DKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYK
Sbjct: 301 DKQVSLFTKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYK 360
Query: 250 DRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLS 309
DRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLS
Sbjct: 361 DRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLS 420
Query: 310 DMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIG 369
DMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIG
Sbjct: 421 DMHYRVKEKIIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIG 480
Query: 370 GPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLV 429
GPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLV
Sbjct: 481 GPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLV 540
Query: 430 YDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGS 489
YDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGS
Sbjct: 541 YDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGS 600
Query: 490 KIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFE 549
KIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFE
Sbjct: 601 KIFCLHVFSISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFE 660
Query: 550 TAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHEN 609
TAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHEN
Sbjct: 661 TAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHEN 720
Query: 610 LALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKA 669
LALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKA
Sbjct: 721 LALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKA 780
Query: 670 IEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQL 729
IEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQL
Sbjct: 781 IEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQL 840
Query: 730 HVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQ 789
HVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQ
Sbjct: 841 HVETQRWDEAFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQ 900
Query: 790 LTNNAVAESRFNDAAYYYWMLSMQCLDIAQADPAQKDTMLGKFYHFQRLAELYHGYHAIH 849
LTNNAVAESRFNDAAYYYWMLSMQCLDIAQ DPAQKDTMLGKFYHFQRLAELYHGYHAIH
Sbjct: 901 LTNNAVAESRFNDAAYYYWMLSMQCLDIAQ-DPAQKDTMLGKFYHFQRLAELYHGYHAIH 959
Query: 850 RHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAY 909
RHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAY
Sbjct: 960 RHTEDPFSVHRPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAY 1019
Query: 910 DKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQ 969
DKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQ
Sbjct: 1020 DKLRGLYIPARFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQ 1079
Query: 970 PFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVE 1029
PFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVE
Sbjct: 1080 PFIFSASSYDVLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVE 1139
Query: 1030 TKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLL 1089
TKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLL
Sbjct: 1140 TKDSIGDEDPFTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLL 1199
Query: 1090 PDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1131
PDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP
Sbjct: 1200 PDASITMCPSCFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1241
>gi|16554621 WD repeat domain 10 isoform 1 [Homo sapiens]
Length = 1292
Score = 2127 bits (5511), Expect = 0.0
Identities = 1065/1156 (92%), Positives = 1072/1156 (92%), Gaps = 72/1156 (6%)
Query: 47 QPLKGHKDTVYCVAY------------AKDGLWSPEQKSVSKHKSSSKIICCSWTNDGQY 94
QP + H D + CV+Y + GLWSPEQKSVSKHKSSSKIICCSWTNDGQY
Sbjct: 138 QPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKHKSSSKIICCSWTNDGQY 197
Query: 95 LALGMFNGIISIRNKNGEEKVKIERPGGSLSPI----------WSICW------------ 132
LALGMFNGIISIRNKNGEEKVKIERPGGSLSPI W W
Sbjct: 198 LALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSRWESFWMNRENEDAEDVI 257
Query: 133 -------------------------------------NPSREERNDILAVADWGQKVSFY 155
+ + EERNDILAVADWGQKVSFY
Sbjct: 258 VNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEERNDILAVADWGQKVSFY 317
Query: 156 QLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWT 215
QLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWT
Sbjct: 318 QLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWT 377
Query: 216 CQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIK 275
CQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIK
Sbjct: 378 CQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIK 437
Query: 276 CKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHI 335
CKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHI
Sbjct: 438 CKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHI 497
Query: 336 ILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLF 395
ILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLF
Sbjct: 498 ILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLF 557
Query: 396 AIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCED 455
AIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCED
Sbjct: 558 AIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCED 617
Query: 456 MLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLD 515
MLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLD
Sbjct: 618 MLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLD 677
Query: 516 RKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKK 575
RKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKK
Sbjct: 678 RKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKK 737
Query: 576 RGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKE 635
+GETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKE
Sbjct: 738 QGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKE 797
Query: 636 TKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAERE 695
TKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAERE
Sbjct: 798 TKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAERE 857
Query: 696 PLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYM 755
PLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYM
Sbjct: 858 PLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYM 917
Query: 756 PYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCL 815
PYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCL
Sbjct: 918 PYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCL 977
Query: 816 DIAQADPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSL 875
DIAQ DPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSL
Sbjct: 978 DIAQ-DPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSL 1036
Query: 876 PKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAK 935
PKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAK
Sbjct: 1037 PKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAK 1096
Query: 936 PFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDE 995
PFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDE
Sbjct: 1097 PFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDE 1156
Query: 996 EAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVP 1055
EAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVP
Sbjct: 1157 EAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVP 1216
Query: 1056 VVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQ 1115
VVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQ
Sbjct: 1217 VVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQ 1276
Query: 1116 HGCCPYCRRCKDDPGP 1131
HGCCPYCRRCKDDPGP
Sbjct: 1277 HGCCPYCRRCKDDPGP 1292
Score = 145 bits (366), Expect = 2e-34
Identities = 97/251 (38%), Positives = 131/251 (52%), Gaps = 37/251 (14%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDG-------------LWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIR 107
YAKDG +W+ + + + K+ S S + +L L F G+
Sbjct: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVM-------SSLHLHL-PFLGLHKTV 112
Query: 108 NKNGEEKVKIERPGGSLSPIWSICWNPSREERNDILAVADW-----------GQKVSFYQ 156
+K + GG + + N ++ ND + + +
Sbjct: 113 RVTATDKAP-KGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWS 171
Query: 157 LSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDG---VRLGTVGEQNSWV 213
K + K ++ + CC S+ G+Y+ LG + +S+ K+G V++ G S +
Sbjct: 172 PEQKSVSKHKSSSKIICC-SWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPI 230
Query: 214 WTCQAKPDSNY 224
W+ P S +
Sbjct: 231 WSICWNPSSRW 241
>gi|41146563 PREDICTED: hypothetical protein LOC653712 [Homo
sapiens]
Length = 121
Score = 184 bits (468), Expect = 3e-46
Identities = 92/96 (95%), Positives = 92/96 (95%), Gaps = 1/96 (1%)
Query: 411 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAS 470
MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGG LNIKAS
Sbjct: 1 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGNLNIKAS 60
Query: 471 TFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQ 506
FPVH QKLQGFVVGYNGSKIFCLHVF ISAVEVPQ
Sbjct: 61 IFPVHWQKLQGFVVGYNGSKIFCLHVF-ISAVEVPQ 95
>gi|169165594 PREDICTED: hypothetical LOC653712 [Homo sapiens]
Length = 121
Score = 183 bits (465), Expect = 7e-46
Identities = 91/96 (94%), Positives = 92/96 (95%), Gaps = 1/96 (1%)
Query: 411 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAS 470
MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGG LNIKAS
Sbjct: 1 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGNLNIKAS 60
Query: 471 TFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQ 506
FPVH QKLQGFVVGYNGSKIFCLHVF ISA+EVPQ
Sbjct: 61 IFPVHWQKLQGFVVGYNGSKIFCLHVF-ISALEVPQ 95
>gi|88971034 PREDICTED: hypothetical LOC653712 [Homo sapiens]
Length = 121
Score = 183 bits (465), Expect = 7e-46
Identities = 91/96 (94%), Positives = 92/96 (95%), Gaps = 1/96 (1%)
Query: 411 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAS 470
MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGG LNIKAS
Sbjct: 1 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGNLNIKAS 60
Query: 471 TFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQ 506
FPVH QKLQGFVVGYNGSKIFCLHVF ISA+EVPQ
Sbjct: 61 IFPVHWQKLQGFVVGYNGSKIFCLHVF-ISALEVPQ 95
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 64.3 bits (155), Expect = 6e-10
Identities = 90/446 (20%), Positives = 181/446 (40%), Gaps = 37/446 (8%)
Query: 377 LLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTK- 435
L+VG ++G I + + N+ I L ++ + +LA++D + +D+D +
Sbjct: 506 LIVGRESGTIQRYSLPNVGLIQKYSLNCRAYQLSLNCNSSRLAIIDISGVLTFFDLDARV 565
Query: 436 ----------ELL-FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVV 484
ELL + + + W D+ + + + P + G++
Sbjct: 566 TDSTGQQVVGELLKLERRDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYIC 625
Query: 485 GYNGSKIFCLHVFSI-SAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTD--------- 534
+ +I + + I E P + + R L I +G+ D
Sbjct: 626 NFEDLEIKSVLLDEILKDPEHPNKDYLINFEIRSLRDSRALIEKVGIKDASQFIEDNPHP 685
Query: 535 --WRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGE-TNNDLFLADVFSY 591
WR LA AL+ LD TA++AF+R +D + ++ + K+ G+ + + A+V Y
Sbjct: 686 RLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFV------KRLGKLLSESMKQAEVVGY 739
Query: 592 QGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFL--GSGDPKETKMLITKQA--DWA 647
G+F EA + Y +LA+ + L + L GSGD ++ + A D+
Sbjct: 740 FGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGDYF 799
Query: 648 RNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKL 707
+ ++ AV+ Y+ + E + L ++A L + + L A ++
Sbjct: 800 ADRQKWLNAVQYYVQGRNQERLAECYYMLEDYEGLENLAISLPE-NHKLLPEIAQMFVRV 858
Query: 708 DSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFK-DDIYMPYAQWLAENDR 766
A +LK K+ V V +W++A L + H + + YA L E ++
Sbjct: 859 GMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNK 918
Query: 767 FEEAQKAFHKAGRQREAVQVLEQLTN 792
+A + + KA +A +++ ++ +
Sbjct: 919 TLDAIELYRKANYFFDAAKLMFKIAD 944
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 64.3 bits (155), Expect = 6e-10
Identities = 90/446 (20%), Positives = 181/446 (40%), Gaps = 37/446 (8%)
Query: 377 LLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTK- 435
L+VG ++G I + + N+ I L ++ + +LA++D + +D+D +
Sbjct: 517 LIVGRESGTIQRYSLPNVGLIQKYSLNCRAYQLSLNCNSSRLAIIDISGVLTFFDLDARV 576
Query: 436 ----------ELL-FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVV 484
ELL + + + W D+ + + + P + G++
Sbjct: 577 TDSTGQQVVGELLKLERRDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYIC 636
Query: 485 GYNGSKIFCLHVFSI-SAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTD--------- 534
+ +I + + I E P + + R L I +G+ D
Sbjct: 637 NFEDLEIKSVLLDEILKDPEHPNKDYLINFEIRSLRDSRALIEKVGIKDASQFIEDNPHP 696
Query: 535 --WRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGE-TNNDLFLADVFSY 591
WR LA AL+ LD TA++AF+R +D + ++ + K+ G+ + + A+V Y
Sbjct: 697 RLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFV------KRLGKLLSESMKQAEVVGY 750
Query: 592 QGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFL--GSGDPKETKMLITKQA--DWA 647
G+F EA + Y +LA+ + L + L GSGD ++ + A D+
Sbjct: 751 FGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGDYF 810
Query: 648 RNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKL 707
+ ++ AV+ Y+ + E + L ++A L + + L A ++
Sbjct: 811 ADRQKWLNAVQYYVQGRNQERLAECYYMLEDYEGLENLAISLPE-NHKLLPEIAQMFVRV 869
Query: 708 DSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFK-DDIYMPYAQWLAENDR 766
A +LK K+ V V +W++A L + H + + YA L E ++
Sbjct: 870 GMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNK 929
Query: 767 FEEAQKAFHKAGRQREAVQVLEQLTN 792
+A + + KA +A +++ ++ +
Sbjct: 930 TLDAIELYRKANYFFDAAKLMFKIAD 955
>gi|55743151 WD repeat domain 19 [Homo sapiens]
Length = 1342
Score = 56.6 bits (135), Expect = 1e-07
Identities = 135/686 (19%), Positives = 260/686 (37%), Gaps = 85/686 (12%)
Query: 198 KDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDS 257
KD + + E+N + T D + + Q G++ + + R AY S
Sbjct: 307 KDMYVILNLDEENKGLGTLSWTDDGQLLALSTQRGSLHVFLTKLPILGDACSTRIAYLTS 366
Query: 258 MTDVIVQHLIT-EQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYS---EDLSDMHY 313
+ +V V + + E + + +A+ LA+ + + Y L + L DM Y
Sbjct: 367 LLEVTVANPVEGELPITVSVDVEPNFVAVGLYHLAVGMNNRAWFYVLGENAVKKLKDMEY 426
Query: 314 RVKEKII--------KKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYI 365
I FE + + IL ++ + F V ++
Sbjct: 427 LGTVASICLHSDYAAALFEGKVQLHLIESEILDAQEERETRLFPAVDDK----------C 476
Query: 366 KVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDEND 425
+++ + L+ G G + ++++ + + +V+ + + +L +DE
Sbjct: 477 RILCHALTSDFLIYGTDTGVVQYFYIEDWQFVNDYRHPVSVKKIFPDPNGTRLVFIDEKS 536
Query: 426 TCLVY---DIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGF 482
VY + T E+ P V W D F Y + K T+ H+ +QG
Sbjct: 537 DGFVYCPVNDATYEIPDFSPTIKGVLWENWPMDKGVFIA--YDDDKVYTYVFHKDTIQGA 594
Query: 483 VVGYNGS---------------KIFC-------------LHVF--SISAVEVPQSAPMY- 511
V GS ++ C H F ++ + PM
Sbjct: 595 KVILAGSTKVPFAHKPLLLYNGELTCQTQSGKVNNIYLSTHGFLSNLKDTGPDELRPMLA 654
Query: 512 QYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIE 571
Q L K F +A+++ + + W ELA L ++ E A + + R+ ++ ++ S+E
Sbjct: 655 QNLMLKRFSDAWEMCRILNDEAAWNELARACLHHMEVEFAIRVYRRIGNVG---IVMSLE 711
Query: 572 ERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSG 631
+ K G + +L + + ++ A LY S ALEM DL ++ A
Sbjct: 712 QIK--GIEDYNLLAGHLAMFTNDYNLAQDLYLASSCPIAALEMRRDLQHWDSALQLAKHL 769
Query: 632 DPKETKMLITK---QADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLI---DI 685
P + + + Q ++A + A E I+ G++ + E C G M I DI
Sbjct: 770 APDQIPFISKEYAIQLEFAGDYVNALAHYEKGIT-GDNKEHDEACLA-GVAQMSIRMGDI 827
Query: 686 ARKLDKAEREPLLL----CATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFA 741
R +++A + P + C L+ + AA+ Y K +++ ++ W +
Sbjct: 828 RRGVNQALKHPSRVLKRDCGAILENMKQFSEAAQLYEKGLYYDKAASVYIRSKNWAK--- 884
Query: 742 LGEKHPEFKDD-IYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQV-LEQLTN-----NA 794
+G+ P I++ YA+ + R++EA A+ A + + +++ L+ L N N
Sbjct: 885 VGDLLPHVSSPKIHLQYAKAKEADGRYKEAVVAYENAKQWQSVIRIYLDHLNNPEKAVNI 944
Query: 795 VAESRFNDAAYYYWMLSMQCLDIAQA 820
V E++ D A +Q D A
Sbjct: 945 VRETQSLDGAKMVARFFLQLGDYGSA 970
Score = 38.5 bits (88), Expect = 0.036
Identities = 46/204 (22%), Positives = 83/204 (40%), Gaps = 29/204 (14%)
Query: 594 KFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEP 653
+F EAA+LY++ + + A +Y + D L + + K + KE
Sbjct: 855 QFSEAAQLYEKGLYYDKAASVYIRSKNWAKVGDLLPHVSSPKIHLQYAKAKEADGRYKE- 913
Query: 654 KAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYA 713
AV Y +A + I I DH L+ E+ ++ T + LD
Sbjct: 914 --AVVAYENAKQWQSVIRIYLDH------------LNNPEKAVNIVRET--QSLDGAKMV 957
Query: 714 AETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFK------------DDIYMPYAQWL 761
A +L++GD S +Q V ++ +EAF L ++H + + ++ Y A +
Sbjct: 958 ARFFLQLGDYGSAIQFLVMSKCNNEAFTLAQQHNKMEIYADIIGSEDTTNEDYQSIALYF 1017
Query: 762 AENDRFEEAQKAFHKAGRQREAVQ 785
R+ +A K F G+ A++
Sbjct: 1018 EGEKRYLQAGKFFLLCGQYSRALK 1041
>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
Length = 1749
Score = 53.9 bits (128), Expect = 8e-07
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 22/235 (9%)
Query: 545 GLDFETAKKAFIRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKR 604
GL + A+ R + L EL+ I +GE + A L+++
Sbjct: 777 GLPAKAARLVLTREELLANTELVEHITAALIKGEL---------------YERAGDLFEK 821
Query: 605 SGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAG 664
+ ALE Y F A + P E L D K+ AA+ YI A
Sbjct: 822 IHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEAR 881
Query: 665 EHVKAIEIC-GDHGW--VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMG 721
+KAIE G W ++D+ + ++ PL+ A + L A E Y K
Sbjct: 882 CSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPLV--AQHYASLQEYEIAEELYTKGD 939
Query: 722 DLKSLVQLHVETQRWDEAFALGEK--HPEFKDDIYMPYAQWLAENDRFEEAQKAF 774
K + ++ + RW++A L K PE +Y+ AQ + + ++ EA++ +
Sbjct: 940 RTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLY 994
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/208 (25%), Positives = 91/208 (43%), Gaps = 31/208 (14%)
Query: 592 QGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDP---KETKMLITKQADWAR 648
QGK+ EA +LY +LA+ MY +++ +G P +T + + K+ +
Sbjct: 984 QGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEG 1043
Query: 649 NIKEP----------KAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLL 698
++E KA V MY ++G +A + G + +A
Sbjct: 1044 RLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVA------------ 1091
Query: 699 LCATYLKKLDSPGYAAETYL-KMGDLKSLVQLHVETQRWDEAFALGEKHPEFKD-DIYMP 756
YL G AA L K+G L++ V + ++ AF L + K ++++
Sbjct: 1092 ----YLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLK 1147
Query: 757 YAQWLAENDRFEEAQKAFHKAGRQREAV 784
YA +L + +FEEA+ F +AG+ +EAV
Sbjct: 1148 YAMFLEDEGKFEEAEAEFIRAGKPKEAV 1175
Score = 34.7 bits (78), Expect = 0.53
Identities = 54/252 (21%), Positives = 102/252 (40%), Gaps = 33/252 (13%)
Query: 548 FETAKKAFIRVQDLRYLELI----SSIEERKKRGETNNDLFLADVFSYQGK-------FH 596
FE A+ FIR + L+ E ++ E ++ +A+V Q + F
Sbjct: 1158 FEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQ 1217
Query: 597 EAAKLYKRSGHENLALEMYTDLCMFEYA----KDFLGS---GDPKETKMLITKQADWARN 649
+A L R+ LAL Y + ++ A KD++ S +E + TK+ AR
Sbjct: 1218 KAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKG--ARG 1275
Query: 650 IKEPKAAVEMYISAGEHVKAIEI------CGDHGWVDMLIDIARKLD------KAEREPL 697
++ + AGE+ +A++ G+ G + A +L + E +
Sbjct: 1276 VEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVV 1335
Query: 698 LLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALG-EKHPEFKDDIYMP 756
L L + AAE YL + +K + +E + W++A + E P ++D +
Sbjct: 1336 LAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQH 1395
Query: 757 YAQWLAENDRFE 768
Y ++L + +
Sbjct: 1396 YKEFLKNQGKVD 1407
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 717 YLKMGDLKSLVQLHVETQRWDEAFALGEK--HPEFKDDIYMPYAQWLAENDRFEEAQKAF 774
+L+ ++ + ++ E RWDE A+ E HP + + Y QWL + + E A +
Sbjct: 702 FLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPAL-EKLRRSYYQWLMDTQQEERAGELQ 760
Query: 775 HKAGRQREAVQV 786
G A+ +
Sbjct: 761 ESQGDGLAAISL 772
Score = 31.6 bits (70), Expect = 4.5
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 17/107 (15%)
Query: 583 LFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITK 642
+FL D +GKF EA + R+G A+ M+ +E A+ + DP ++
Sbjct: 1150 MFLED----EGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVG 1205
Query: 643 QADWARNIKE-------------PKAAVEMYISAGEHVKAIEICGDH 676
QA A K+ P A+ Y AG A+ IC D+
Sbjct: 1206 QARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDY 1252
Score = 30.4 bits (67), Expect = 9.9
Identities = 27/142 (19%), Positives = 64/142 (45%), Gaps = 5/142 (3%)
Query: 649 NIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLD 708
+++E + A E+Y AI++ G + +A K + E + +L T ++++
Sbjct: 924 SLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPE-DVSVLYITQAQEME 982
Query: 709 SPGYAAET---YLKMGDLKSLVQLHVETQRWDEAFAL-GEKHPEFKDDIYMPYAQWLAEN 764
G E Y+ + + + ++ + + +D+ L G+ HP+ D ++ + L
Sbjct: 983 KQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAE 1042
Query: 765 DRFEEAQKAFHKAGRQREAVQV 786
R +EA+ + +A + V +
Sbjct: 1043 GRLQEAEYHYLEAQEWKATVNM 1064
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 48.5 bits (114), Expect = 4e-05
Identities = 40/202 (19%), Positives = 84/202 (41%), Gaps = 11/202 (5%)
Query: 103 IISIRNKNGEEKVKIERPGGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLSGKQI 162
II + KN + I+ G IW + +PS+ D+ A + L+ K++
Sbjct: 1668 IIEVGEKNAASNILID--GHMEGEIWGLATHPSK----DLFISASNDGTARIWDLADKKL 1721
Query: 163 GKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRL-GTVGEQNSWVWTCQAKPD 221
+L C +Y GE + +G + + + + +++ G ++ S + + PD
Sbjct: 1722 LNKVSLGHAARCAAYSPDGEMVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPD 1781
Query: 222 SNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCKELVK 281
+ ++ VG + T+ FY L G +R Y + ++Q + I+
Sbjct: 1782 NRFLAVGSSEHTVDFYDL----TQGTNLNRIGYCKDIPSFVIQMDFSADGKYIQVSTGAY 1837
Query: 282 KIAIYRNRLAIQLPEKILIYEL 303
K ++ L Q+ E ++I ++
Sbjct: 1838 KRQVHEVPLGKQVTEAVVIEKI 1859
Score = 33.5 bits (75), Expect = 1.2
Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 17/105 (16%)
Query: 8 RDKAEHCINDIAFKPDGTQLILA-AGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGL 66
R E + +AF PDG+QL L +V D T + +K K+ ++ + ++ DG
Sbjct: 362 RCNMEEAVRSVAFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGS 421
Query: 67 W---------------SPEQKSVSK-HKSSSKIICCSWTNDGQYL 95
+ + K + + KS S I W+ D +YL
Sbjct: 422 YLAVGSNDGPVDVYAVAQRYKKIGECSKSLSFITHIDWSLDSKYL 466
Score = 30.8 bits (68), Expect = 7.6
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 9/74 (12%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLI---LAAGSRLLVYDTSDGTLLQPLKGHKDTVY 57
++ V +D H + +AF DG +L L A + + ++D G LL GH D ++
Sbjct: 95 VQTVSLLKDVHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIF 154
Query: 58 CVAYAKDGLWSPEQ 71
++ W P Q
Sbjct: 155 DIS------WDPYQ 162
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 43.9 bits (102), Expect = 9e-04
Identities = 50/205 (24%), Positives = 93/205 (45%), Gaps = 28/205 (13%)
Query: 15 INDIAFKPDGTQLILAAGSR---LLVYDTSD-GTLLQPLKGHKDTVYCVAYAKDG----- 65
+ D+ F PDG+ LIL + SR L V+D D G +++ L+GH++ VY A++ D
Sbjct: 173 VRDLTFAPDGS-LILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCS 231
Query: 66 --------LWSPEQKSVSKHKSS--SKIICCSWTNDGQYLALGMFNGIISIRN-KNGEEK 114
LW+ ++ ++ + ++ C ++ DG LA ++ + I + NG+
Sbjct: 232 VGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDIL 291
Query: 115 VKIERPGGSLSPIW----SICWNPSREERNDILAVADWG--QKVSFYQLSGKQIGKDRAL 168
++ +PI+ + W S +D L VA + V F+++ + L
Sbjct: 292 MEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPL 351
Query: 169 NFDPCCISYFTKGEYILLGGSDKQV 193
+ CC ++ T G + G D V
Sbjct: 352 SNGLCC-AFSTDGSVLAAGTHDGSV 375
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 43.9 bits (102), Expect = 9e-04
Identities = 50/205 (24%), Positives = 93/205 (45%), Gaps = 28/205 (13%)
Query: 15 INDIAFKPDGTQLILAAGSR---LLVYDTSD-GTLLQPLKGHKDTVYCVAYAKDG----- 65
+ D+ F PDG+ LIL + SR L V+D D G +++ L+GH++ VY A++ D
Sbjct: 27 VRDLTFAPDGS-LILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCS 85
Query: 66 --------LWSPEQKSVSKHKSS--SKIICCSWTNDGQYLALGMFNGIISIRN-KNGEEK 114
LW+ ++ ++ + ++ C ++ DG LA ++ + I + NG+
Sbjct: 86 VGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDIL 145
Query: 115 VKIERPGGSLSPIW----SICWNPSREERNDILAVADWG--QKVSFYQLSGKQIGKDRAL 168
++ +PI+ + W S +D L VA + V F+++ + L
Sbjct: 146 MEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPL 205
Query: 169 NFDPCCISYFTKGEYILLGGSDKQV 193
+ CC ++ T G + G D V
Sbjct: 206 SNGLCC-AFSTDGSVLAAGTHDGSV 229
>gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog
[Homo sapiens]
Length = 518
Score = 42.4 bits (98), Expect = 0.003
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 15/115 (13%)
Query: 15 INDIAFKPDGTQLILAAGSRLLVYDT-SDGTLLQPLKGHKDTVYCVAYAKDG-------- 65
+ + P G L+ A G + V+D G LL LK H TV C+ + G
Sbjct: 209 VESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSL 268
Query: 66 ------LWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEK 114
+ K V ++ I+ + ++ + + +GM NGI+S++++ E K
Sbjct: 269 DRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAK 323
>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
Length = 770
Score = 41.6 bits (96), Expect = 0.004
Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 15/115 (13%)
Query: 18 IAFKPDGTQLI-LAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG--LWS------ 68
+A PD + + V+D + TL++ +GH D C+ + DG LW+
Sbjct: 580 LAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNT 639
Query: 69 ------PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKI 117
E + + +H +S+I + G++LA+GM + + + + N +K ++
Sbjct: 640 VRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQL 694
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/163 (20%), Positives = 71/163 (43%), Gaps = 11/163 (6%)
Query: 103 IISIRNKNGEEKVKIERPGGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLSGKQI 162
II + KN + + G PIW + +PSR+ L+ A+ G V + ++ K++
Sbjct: 1683 IIEVGEKNAACNILVN--GHVDGPIWGLATHPSRDF---FLSAAEDGT-VRLWDIADKKM 1736
Query: 163 GKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRL-GTVGEQNSWVWTCQAKPD 221
L + Y +G+ + +G + + + +++ G ++ + + PD
Sbjct: 1737 LNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPD 1796
Query: 222 SNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQ 264
S Y+ VG + ++ FY L G +R +Y + ++Q
Sbjct: 1797 SRYLAVGSSENSVDFYDLTL----GPTLNRISYCKDIPSFVIQ 1835
Score = 30.4 bits (67), Expect = 9.9
Identities = 14/65 (21%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 174 CISYFTKGEYILLGGSDKQVSLF-TKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDG 232
C + G ++ LG D ++ +D + + ++ + + PD Y+ VGC D
Sbjct: 371 CAAVNADGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDS 430
Query: 233 TISFY 237
++ Y
Sbjct: 431 SVDIY 435
>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
Length = 773
Score = 41.2 bits (95), Expect = 0.006
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 15/115 (13%)
Query: 18 IAFKPDGTQLI-LAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG--LWS------ 68
+A PD + + V+D + TL++ +GH D C+ + DG LW+
Sbjct: 583 LAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNT 642
Query: 69 ------PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKI 117
E + + +H +S+I + G++LA+GM N + + + +K ++
Sbjct: 643 VRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQL 697
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 40.4 bits (93), Expect = 0.010
Identities = 42/199 (21%), Positives = 83/199 (41%), Gaps = 11/199 (5%)
Query: 76 KHKSSSKIICCSWTNDGQYLALGMFNGIISIRN-KNGEEKVKIE---RPGGSLSPIWSIC 131
K S + C ++ DGQYL G +G I + N G+ + ++ + + +C
Sbjct: 210 KFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLC 269
Query: 132 WNPSREERNDILAVADWGQKVSFYQLSGKQIGK--DRALNFDPCCISYFTKGEYILLGGS 189
SR+ ++LA K+ +++ Q + +RA + C+S+ IL
Sbjct: 270 MCFSRD--TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASF 327
Query: 190 DKQVSLF-TKDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLY 248
D+ + + K G L +S+V D +Y++ DGT+ + + + +
Sbjct: 328 DQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTF 387
Query: 249 KDRYAYRDSMTDVIVQHLI 267
K + + TD+ V +I
Sbjct: 388 KSLGS--TAGTDITVNSVI 404
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 39.3 bits (90), Expect = 0.021
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG 65
I+ + F P+G L A R+L++D G ++ LKGH DTV + +++DG
Sbjct: 672 IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDG 723
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 39.3 bits (90), Expect = 0.021
Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 15/115 (13%)
Query: 18 IAFKPDGTQLI-LAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG--LWS------ 68
+A PD + + V+D + TL++ +GH D C+ + DG LW+
Sbjct: 579 LAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNT 638
Query: 69 ------PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKI 117
E + + +H +S+I + G++LA+GM + + + + +K ++
Sbjct: 639 VRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQL 693
>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
sapiens]
Length = 760
Score = 39.3 bits (90), Expect = 0.021
Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 15/115 (13%)
Query: 18 IAFKPDGTQLI-LAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG--LWS------ 68
+A PD + + V+D + TL++ +GH D C+ + DG LW+
Sbjct: 570 LAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNT 629
Query: 69 ------PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKI 117
E + + +H +S+I + G++LA+GM + + + + +K ++
Sbjct: 630 VRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQL 684
>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
sapiens]
Length = 772
Score = 39.3 bits (90), Expect = 0.021
Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 15/115 (13%)
Query: 18 IAFKPDGTQLI-LAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG--LWS------ 68
+A PD + + V+D + TL++ +GH D C+ + DG LW+
Sbjct: 582 LAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNT 641
Query: 69 ------PEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKI 117
E + + +H +S+I + G++LA+GM + + + + +K ++
Sbjct: 642 VRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQL 696
>gi|46409657 WD repeat domain 56 [Homo sapiens]
Length = 777
Score = 38.1 bits (87), Expect = 0.048
Identities = 102/641 (15%), Positives = 235/641 (36%), Gaps = 125/641 (19%)
Query: 71 QKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSI 130
+KSV H + ++ W +G L +G I I +K G + + + G +P++S+
Sbjct: 99 EKSVEAHCGA--VLAGRWNYEGTALVTVGEDGQIKIWSKTGMLRSTLAQQG---TPVYSV 153
Query: 131 CWNPSREE-------------------------RNDILAVADWGQ------------KVS 153
W P E+ + I+ DW K
Sbjct: 154 AWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYK 213
Query: 154 FYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWV 213
+ G+ + + +++ GE +G S + L K G +
Sbjct: 214 VWDSYGRPLYNSQPHEHPITSVAWAPDGELFAVG-SFHTLRLCDKTGWSYALEKPNTGSI 272
Query: 214 WTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVR 273
+ D + C +G + F ++ H +K+ + V++++ +
Sbjct: 273 FNIAWSIDGTQIAGACGNGHVVFAHVVEQ--HWEWKNFQVTLTKRRAMQVRNVLNDAVDL 330
Query: 274 IKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCAN 333
++ ++ V K ++ L + + ++ + + + + + +KE + +L++
Sbjct: 331 LEFRDRVIKASLNYAHLVVSTSLQCYVFSTKNWN-TPIIFDLKEGTV-----SLILQAER 384
Query: 334 HIILCQEKRLQCLSFSG---------------------------VKEREWQMESLIRYIK 366
H +L + S+ G + R+ E +I +
Sbjct: 385 HFLLVDGSSIYLYSYEGRFISSPKFPGMRTDILNAQTVSLSNDTIAIRDKADEKIIFLFE 444
Query: 367 VIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDT 426
G P +G + KN +IL+I +D K T + +K+A +D+N
Sbjct: 445 ASTGKPLGDGKFLSHKN-EILEIALDQ-------KGLT---------NDRKIAFIDKNRD 487
Query: 427 CLVYDIDT----KELLFQEPNANSVAWNTQCEDMLC-----------FSGGGYLNIKAST 471
+ + ++++ +++AWN C ++LC + Y++
Sbjct: 488 LCITSVKRFGKEEQIIKLGTMVHTLAWNDTC-NILCGLQDTRFIVWYYPNTVYVDRDILP 546
Query: 472 FPVHRQKLQGF-----VVGYNGSKIFCLHVFSISAVEV---PQSAPMYQYLDRKLFKEAY 523
++ + F +V + G+++ S V + P A +++Y+ +++A
Sbjct: 547 KTLYERDASEFSKNPHIVSFVGNQVTIRRADG-SLVHISITPYPAILHEYVSSSKWEDAV 605
Query: 524 QIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKKRGETNNDL 583
++ T W LA A+ D TA+ A+ + ++ ++ I+SI+ + +
Sbjct: 606 RLCRFVKEQTMWACLAAMAVANRDMTTAEIAYAAIGEIDKVQYINSIKNLPSK-----ES 660
Query: 584 FLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYA 624
+A + + G EA + ++G A+++ +L +E A
Sbjct: 661 KMAHILLFSGNIQEAEIVLLQAGLVYQAIQININLYNWERA 701
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 37.7 bits (86), Expect = 0.062
Identities = 51/240 (21%), Positives = 84/240 (35%), Gaps = 68/240 (28%)
Query: 39 DTSDGTLLQPLKGHKDTVYCVAYAKDGLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALG 98
D + GT ++ L+GH VY + D SS ++ CS +Y LG
Sbjct: 328 DDNAGTEMKILRGHCGPVYSTRFLAD---------------SSGLLSCSEDMSIRYWDLG 372
Query: 99 MFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLS 158
F + + G P+W + +P S Y S
Sbjct: 373 SFTNTVLYQ--------------GHAYPVWDLDISP-----------------YSLYFAS 401
Query: 159 GKQIGKDRALNFDPC--------------CISYFTKGEYILLGGSDKQVSLFTK---DGV 201
G R +FD C+ + Y+ G +DK V L++ + V
Sbjct: 402 GSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSV 461
Query: 202 RLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDV 261
RL T G + V + P+ Y+ +D + + L T LYK+ + D++T +
Sbjct: 462 RLFT-GHRGP-VLSLAFSPNGKYLASAGEDQRLKLWDLASGT---LYKELRGHTDNITSL 516
Score = 37.7 bits (86), Expect = 0.062
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 18 IAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKD-GLWSPEQKSVS 75
+AF P+G L A RL ++D + GTL + L+GH D + + ++ D GL + S
Sbjct: 474 LAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNS 533
Query: 76 KHKSSSKIICCSWTNDGQYLAL-GMFNGIIS 105
+ CS DG L G++ G +S
Sbjct: 534 VRVWDIRNTYCSAPADGSSSELVGVYTGQMS 564
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 37.7 bits (86), Expect = 0.062
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 39/214 (18%)
Query: 15 INDIAFKPDGTQLILAAGSR---LLVYDTSD-GTLLQPLKGHKDTVYCVAYAKD------ 64
+ D++F P G+ LIL + SR L ++D + G +Q L GH VYC + + D
Sbjct: 156 VRDLSFTPSGS-LILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCS 214
Query: 65 -------GLWSPEQ----KSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEE 113
LWS + + H+SS ++ C ++ D L ++ + + + E
Sbjct: 215 AAGEKSVFLWSMRSYTLIRKLEGHQSS--VVSCDFSPDSALLVTASYDTNVIMWDPYTGE 272
Query: 114 KVK----------IERPGGSLSPIWSICWNPSREERNDILAVADWGQKVSFYQLSGKQIG 163
+++ ++ +S + S+C++P E + VAD + + + L K
Sbjct: 273 RLRSLHHTQVDPAMDDSDVHISSLRSVCFSP---EGLYLATVAD-DRLLRIWALELKTPI 328
Query: 164 KDRALNFDPCCISYFTKGEYILLGGSDKQVSLFT 197
+ CC ++F G I G D V +T
Sbjct: 329 AFAPMTNGLCC-TFFPHGGVIATGTRDGHVQFWT 361
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 37.7 bits (86), Expect = 0.062
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 15 INDIAFKPDGTQLILAAG-SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG 65
+N I+F P G LI A+ L + D +G L+ L+GH V+ V+++K G
Sbjct: 231 VNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGG 282
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 37.4 bits (85), Expect = 0.081
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYC 58
I+D+A+ D L+ A+ + L ++D S G L+ LKGH + V+C
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFC 134
Score = 32.0 bits (71), Expect = 3.4
Identities = 22/110 (20%), Positives = 47/110 (42%), Gaps = 20/110 (18%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDG-------- 65
++ + F P+G L ++ +L+ ++ DG + + GHK + VA++ D
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 66 -----LWSPEQ----KSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISI 106
+W K++ H S+ + CC++ + G F+ + I
Sbjct: 108 DKTLKIWDVSSGKCLKTLKGH--SNYVFCCNFNPQSNLIVSGSFDESVRI 155
Score = 31.2 bits (69), Expect = 5.8
Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCV 59
++ + F P+G ++ A + L ++D S G L+ GHK+ YC+
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 37.4 bits (85), Expect = 0.081
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYC 58
I+D+A+ D L+ A+ + L ++D S G L+ LKGH + V+C
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFC 134
Score = 32.0 bits (71), Expect = 3.4
Identities = 22/110 (20%), Positives = 47/110 (42%), Gaps = 20/110 (18%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDG-------- 65
++ + F P+G L ++ +L+ ++ DG + + GHK + VA++ D
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 66 -----LWSPEQ----KSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISI 106
+W K++ H S+ + CC++ + G F+ + I
Sbjct: 108 DKTLKIWDVSSGKCLKTLKGH--SNYVFCCNFNPQSNLIVSGSFDESVRI 155
Score = 31.2 bits (69), Expect = 5.8
Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCV 59
++ + F P+G ++ A + L ++D S G L+ GHK+ YC+
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 15 INDIAFKPDGTQLILAAG-SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDG 65
+N ++F P G LI A+ S L + D +G LL L GH+ VA+++ G
Sbjct: 194 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,320,602
Number of Sequences: 37866
Number of extensions: 1912864
Number of successful extensions: 4610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 4332
Number of HSP's gapped (non-prelim): 308
length of query: 1131
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1018
effective length of database: 13,968,660
effective search space: 14220095880
effective search space used: 14220095880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.