Search of human proteins with 16507237

Search of human proteins with 16507237

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
         (654 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]                1282   0.0  
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]        803   0.0  
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]               786   0.0  
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]               786   0.0  
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]                 785   0.0  
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]           782   0.0  
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]       766   0.0  
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]       632   0.0  
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]       598   e-171
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]      307   2e-83
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]                 284   2e-76
gi|48928056 heat shock protein 70kDa family member 13 precursor ...   283   5e-76
gi|42544159 heat shock 105kD [Homo sapiens]                           263   5e-70
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]            252   9e-67
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]          207   3e-53
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]            207   3e-53
gi|38348298 ankyrin repeat domain 45 [Homo sapiens]                    60   5e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    44   4e-04
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    43   8e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    40   0.005
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]         40   0.009
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    39   0.012
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    39   0.015
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    39   0.015
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    39   0.015
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    39   0.015
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]                    38   0.026
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       38   0.026
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    38   0.034
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]            37   0.044

>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
          Length = 654

 Score = 1282 bits (3317), Expect = 0.0
 Identities = 654/654 (100%), Positives = 654/654 (100%)

Query: 1   MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR 60
           MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
Sbjct: 1   MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR 60

Query: 61  ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV 120
           ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
Sbjct: 61  ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV 120

Query: 121 EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ 180
           EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
Sbjct: 121 EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ 180

Query: 181 RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG 240
           RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
Sbjct: 181 RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG 240

Query: 241 VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS 300
           VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
Sbjct: 241 VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS 300

Query: 301 SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV 360
           SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
Sbjct: 301 SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV 360

Query: 361 LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC 420
           LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
Sbjct: 361 LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC 420

Query: 421 PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG 480
           PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
Sbjct: 421 PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG 480

Query: 481 TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER 540
           TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
Sbjct: 481 TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER 540

Query: 541 MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE 600
           MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
Sbjct: 541 MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE 600

Query: 601 KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL 654
           KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL
Sbjct: 601 KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL 654


>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
          Length = 646

 Score =  803 bits (2075), Expect = 0.0
 Identities = 410/620 (66%), Positives = 507/620 (81%), Gaps = 6/620 (0%)

Query: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
           G  VGIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  N
Sbjct: 4   GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 62

Query: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
           P NTVFDAKRLIGR ++D  VQ D+K  PF VV    +P +QV+  G +TK+F PEE+S+
Sbjct: 63  PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKG-ETKSFYPEEVSS 121

Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
           MVLTKMKE AEAYLGK VT+AVVTVPAYFND+QRQATKDAGTIAGLNV+RIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181

Query: 208 AYGLDKREG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266
           AYGLDK+ G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ HF
Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241

Query: 267 IKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326
           I  +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA IEI+S YEG DF  ++TRA+
Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301

Query: 327 FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386
           FEELN DLFR T+ PV+K L D+ L KS I +IVLVGGSTRIPKIQ+L+++FFNGKE ++
Sbjct: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361

Query: 387 GINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444
            INPDEAVAYGAAVQA +LSGD  ++  DL+LLDV PL+LGIET GGVMT LI RNT +P
Sbjct: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421

Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504
           TK++Q F+T SDNQP V I+VYEGER +TKDN+LLG F+LTGIPPAPRGVPQIEVTF+ID
Sbjct: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDID 481

Query: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564
            NGIL V+A DK TG +NKITITND+ RL+ E+IERMV +AEK+  ED+K ++++ ++N 
Sbjct: 482 ANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNS 541

Query: 565 LESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624
           LESYA+++K  + D EKL GK++ EDK+ +     E I WL+ +Q A+ E+F+ ++KELE
Sbjct: 542 LESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600

Query: 625 EIVQPIISKLYGSAGPPPTG 644
           ++  PII+KLY SAG  P G
Sbjct: 601 KVCNPIITKLYQSAGGMPGG 620


>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score =  786 bits (2030), Expect = 0.0
 Identities = 398/618 (64%), Positives = 503/618 (81%), Gaps = 7/618 (1%)

Query: 31  VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90
           +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP+N
Sbjct: 7   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQN 65

Query: 91  TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150
           TVFDAKRLIGR + DP VQ D+K  PF+V+    KP +QV   G +TK F PEEIS+MVL
Sbjct: 66  TVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKG-ETKAFYPEEISSMVL 124

Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210
           TKMKE AEAYLG  VT+AV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAIAYG
Sbjct: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184

Query: 211 LDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269
           LD+  +GE+N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF++ 
Sbjct: 185 LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEE 244

Query: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEE 329
           +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA +EI+S +EG DF  ++TRA+FEE
Sbjct: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEE 304

Query: 330 LNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGIN 389
           L  DLFRST++PV+K L D+ L K+ I ++VLVGGSTRIPK+Q+L+++FFNG++ ++ IN
Sbjct: 305 LCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSIN 364

Query: 390 PDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKK 447
           PDEAVAYGAAVQA +L GD  ++  DL+LLDV PL+LG+ET GGVMT LI RN+ +PTK+
Sbjct: 365 PDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQ 424

Query: 448 SQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNG 507
           +QIF+T SDNQP V I+VYEGER +TKDN+LLG F+L+GIPPAPRGVPQIEVTF+ID NG
Sbjct: 425 TQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANG 484

Query: 508 ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELES 567
           IL VTA DK TG  NKITITND+ RL+ EEIERMV +AEK+  ED+  +ER+  +N LES
Sbjct: 485 ILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALES 544

Query: 568 YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIV 627
           YA+++K+ + D E L GK+S  DK+ +    +E I WL+++  A+ ++F+ K+KELE++ 
Sbjct: 545 YAFNMKSAVED-EGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVC 603

Query: 628 QPIISKLY-GSAGPPPTG 644
            PIIS LY G+ GP P G
Sbjct: 604 NPIISGLYQGAGGPGPGG 621


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score =  786 bits (2030), Expect = 0.0
 Identities = 398/618 (64%), Positives = 503/618 (81%), Gaps = 7/618 (1%)

Query: 31  VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90
           +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP+N
Sbjct: 7   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQN 65

Query: 91  TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150
           TVFDAKRLIGR + DP VQ D+K  PF+V+    KP +QV   G +TK F PEEIS+MVL
Sbjct: 66  TVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKG-ETKAFYPEEISSMVL 124

Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210
           TKMKE AEAYLG  VT+AV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAIAYG
Sbjct: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184

Query: 211 LDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269
           LD+  +GE+N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF++ 
Sbjct: 185 LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEE 244

Query: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEE 329
           +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA +EI+S +EG DF  ++TRA+FEE
Sbjct: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEE 304

Query: 330 LNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGIN 389
           L  DLFRST++PV+K L D+ L K+ I ++VLVGGSTRIPK+Q+L+++FFNG++ ++ IN
Sbjct: 305 LCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSIN 364

Query: 390 PDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKK 447
           PDEAVAYGAAVQA +L GD  ++  DL+LLDV PL+LG+ET GGVMT LI RN+ +PTK+
Sbjct: 365 PDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQ 424

Query: 448 SQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNG 507
           +QIF+T SDNQP V I+VYEGER +TKDN+LLG F+L+GIPPAPRGVPQIEVTF+ID NG
Sbjct: 425 TQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANG 484

Query: 508 ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELES 567
           IL VTA DK TG  NKITITND+ RL+ EEIERMV +AEK+  ED+  +ER+  +N LES
Sbjct: 485 ILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALES 544

Query: 568 YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIV 627
           YA+++K+ + D E L GK+S  DK+ +    +E I WL+++  A+ ++F+ K+KELE++ 
Sbjct: 545 YAFNMKSAVED-EGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVC 603

Query: 628 QPIISKLY-GSAGPPPTG 644
            PIIS LY G+ GP P G
Sbjct: 604 NPIISGLYQGAGGPGPGG 621


>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
          Length = 639

 Score =  785 bits (2028), Expect = 0.0
 Identities = 400/618 (64%), Positives = 496/618 (80%), Gaps = 9/618 (1%)

Query: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
           G  +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  N
Sbjct: 5   GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 63

Query: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
           P NT+FDAKRLIGR + D +VQ D+K  PF+VV +  KP +QV+  G +TKTF PEEIS+
Sbjct: 64  PTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKG-ETKTFFPEEISS 122

Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
           MVLTKMKE AEAYLG KV  AV+TVPAYFND+QRQATKDAGTI GLNV+RIINEPTAAAI
Sbjct: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182

Query: 208 AYGLDKRE---GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 264
           AYGLDK+    GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ 
Sbjct: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242

Query: 265 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTR 324
           H  + +K+K  KD+  + RAV++LR   E+AKR LSS  QA IEI+S YEG DF  ++TR
Sbjct: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302

Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384
           A+FEELN DLFR T++PV+K L D+ L K  I EIVLVGGSTRIPKIQ+L+++FFNGKE 
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362

Query: 385 SRGINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTV 442
           ++ INPDEAVAYGAAVQA +L GD  ++  DL+LLDV PL+LGIET GGVMT LI RNT 
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422

Query: 443 VPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFE 502
           +PTK++Q F+T SDNQ +V ++VYEGER +TKDN+LLG FDLTGIPPAPRGVPQIEVTF+
Sbjct: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482

Query: 503 IDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTR 562
           ID NGIL VTA DK TG +NKITITND+ RL+ ++I+RMV +AE++  ED+  ++R+  +
Sbjct: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542

Query: 563 NELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKE 622
           N LESY Y++K  + D EKL GK+S +DK  +    +E I WL+ +Q A+ ++++ K+KE
Sbjct: 543 NALESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKE 601

Query: 623 LEEIVQPIISKLYGSAGP 640
           LE +  PIISKLY   GP
Sbjct: 602 LERVCNPIISKLY-QGGP 618


>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score =  782 bits (2019), Expect = 0.0
 Identities = 398/618 (64%), Positives = 498/618 (80%), Gaps = 8/618 (1%)

Query: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
           G  +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  N
Sbjct: 6   GIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 64

Query: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
           P+NTVFDAKRLIGR +NDP VQ D+K  PF+V+ +  KP + V   G + K F PEEIS+
Sbjct: 65  PQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKG-ENKAFYPEEISS 123

Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
           MVLTK+KETAEA+LG  VT+AV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAI
Sbjct: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183

Query: 208 AYGLDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266
           AYGLDK  +GE+++L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF
Sbjct: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243

Query: 267 IKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326
           ++ +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA +EI+S YEG DF  ++TRA+
Sbjct: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303

Query: 327 FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386
           FEEL  DLFR T++PV+K L D+ + K+ I +IVLVGGSTRIPK+Q+L++++FNG++ ++
Sbjct: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363

Query: 387 GINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444
            INPDEAVAYGAAVQA +L GD  +   DL+LLDV PL+LG+ET GGVMT LI RN+ +P
Sbjct: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423

Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504
           TK++QIF+T SDNQP V I+VYEGER +TKDN+LLG FDLTGIPPAPRGVPQIEVTF+ID
Sbjct: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483

Query: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564
            NGIL VTA DK TG  NKITITND+ RL+ EEIERMV DAEK+  ED+  +E+I  +N 
Sbjct: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543

Query: 565 LESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624
           LESYA+++K+ + D E L GK+S  DK  +     E + WLE +Q A+ ++F  K+KELE
Sbjct: 544 LESYAFNMKSVVSD-EGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELE 602

Query: 625 EIVQPIISKLY--GSAGP 640
           ++  PII+KLY  G  GP
Sbjct: 603 QMCNPIITKLYQGGCTGP 620


>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
          Length = 643

 Score =  766 bits (1977), Expect = 0.0
 Identities = 387/614 (63%), Positives = 492/614 (80%), Gaps = 6/614 (0%)

Query: 31  VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90
           VGIDLGTTYSCVGVF+ GRVEI+ANDQGNR TPSYVAFT + ERL+GDAAK+Q   NP N
Sbjct: 9   VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFT-DTERLVGDAAKSQAALNPHN 67

Query: 91  TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150
           TVFDAKRLIGR + D +VQ D+K  PF+VV +  KP ++V   G + KTF PEEIS+MVL
Sbjct: 68  TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRG-EDKTFYPEEISSMVL 126

Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210
           +KMKETAEAYLG+ V HAV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAIAYG
Sbjct: 127 SKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYG 186

Query: 211 LDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269
           LD+R  GE+N+L+FDLGGGTFDVS+L+ID GVFEV AT GDTHLGGEDFD R++ HF++ 
Sbjct: 187 LDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEE 246

Query: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEE 329
           +++K GKD+  + RA+++LR   E+AKR LSS  QA +EI+S +EG DF  ++TRA+FEE
Sbjct: 247 FRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEE 306

Query: 330 LNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGIN 389
           L  DLFRST++PV+K L D+ L K+ I ++VLVGGSTRIPK+Q+L+++FFNGKE ++ IN
Sbjct: 307 LCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSIN 366

Query: 390 PDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKK 447
           PDEAVAYGAAVQA VL GD  +   DL+LLDV PL+LG+ET GGVMT LI RN  +PTK+
Sbjct: 367 PDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQ 426

Query: 448 SQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNG 507
           +Q F+T SDNQP V I+VYEGER +TKDN+LLG F+L+GIPPAPRGVPQIEVTF+ID NG
Sbjct: 427 TQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANG 486

Query: 508 ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELES 567
           IL VTA D+ TG  NKITITND+ RL+ EE+ERMV++AE++  ED+  ++R+  +N LE+
Sbjct: 487 ILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEA 546

Query: 568 YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIV 627
           + + +K  +  +E L  K+  ED+  M+    E + WLE +Q A+ E+++ +K+ELE+I 
Sbjct: 547 HVFHVKGSL-QEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQIC 605

Query: 628 QPIISKLYGSAGPP 641
           +PI S+LYG  G P
Sbjct: 606 RPIFSRLYGGPGVP 619


>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
          Length = 493

 Score =  632 bits (1630), Expect = 0.0
 Identities = 326/472 (69%), Positives = 391/472 (82%), Gaps = 6/472 (1%)

Query: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
           G  VGIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  N
Sbjct: 4   GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 62

Query: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
           P NTVFDAKRLIGR ++D  VQ D+K  PF VV    +P +QV+  G +TK+F PEE+S+
Sbjct: 63  PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKG-ETKSFYPEEVSS 121

Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
           MVLTKMKE AEAYLGK VT+AVVTVPAYFND+QRQATKDAGTIAGLNV+RIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181

Query: 208 AYGLDKREG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266
           AYGLDK+ G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ HF
Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241

Query: 267 IKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326
           I  +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA IEI+S YEG DF  ++TRA+
Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301

Query: 327 FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386
           FEELN DLFR T+ PV+K L D+ L KS I +IVLVGGSTRIPKIQ+L+++FFNGKE ++
Sbjct: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361

Query: 387 GINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444
            INPDEAVAYGAAVQA +LSGD  ++  DL+LLDV PL+LGIET GGVMT LI RNT +P
Sbjct: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421

Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPA-PRGVP 495
           TK++Q F+T SDNQP V I+VYEGER +TKDN+LLG F+LTG+P   P G P
Sbjct: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473


>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score =  598 bits (1543), Expect = e-171
 Identities = 330/635 (51%), Positives = 436/635 (68%), Gaps = 19/635 (2%)

Query: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
           G VVGIDLGTT SCV V +  + +++ N +G R TPS VAFT +GERL+G  AK Q  +N
Sbjct: 53  GAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112

Query: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
           P NT +  KRLIGR ++DP VQ+DIK +PFK+V + +     V+  G   K ++P +I A
Sbjct: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIV-RASNGDAWVEAHG---KLYSPSQIGA 168

Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
            VL KMKETAE YLG    +AV+TVPAYFND+QRQATKDAG I+GLNV+R+INEPTAAA+
Sbjct: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228

Query: 208 AYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFI 267
           AYGLDK E +K I V+DLGGGTFD+S+L I  GVFEV +TNGDT LGGEDFDQ ++ H +
Sbjct: 229 AYGLDKSE-DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIV 287

Query: 268 KLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGED----FSETLT 323
           K +K++TG D+ KDN A+Q++R   EKAK  LSS  Q  I +             +  LT
Sbjct: 288 KEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLT 347

Query: 324 RAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKE 383
           RA+FE +  DL R T+ P QK ++D+++ KSDI E++LVGG TR+PK+QQ V++ F G+ 
Sbjct: 348 RAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GRA 406

Query: 384 PSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVV 443
           PS+ +NPDEAVA GAA+Q GVL+GD    D++LLDV PL+LGIET+GGV TKLI RNT +
Sbjct: 407 PSKAVNPDEAVAIGAAIQGGVLAGD--VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTI 464

Query: 444 PTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEI 503
           PTKKSQ+FSTA+D Q  V IKV +GER +  DN LLG F L GIPPAPRGVPQIEVTF+I
Sbjct: 465 PTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDI 524

Query: 504 DVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRN 563
           D NGI+ V+A+DKGTG + +I I      L+ ++IE MV +AEK+AEED++ KER++  N
Sbjct: 525 DANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVN 583

Query: 564 ELESYAYSLKNQIGD-KEKLG----GKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKA 618
             E   +  + ++ + K++L      KL  E  +  E    +  E  E+ + A     +A
Sbjct: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643

Query: 619 KKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDE 653
             K  E   + + S+  GS G   TGE+   +K+E
Sbjct: 644 SLKLFEMAYKKMASEREGS-GSSGTGEQKEDQKEE 677


>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
          Length = 509

 Score =  307 bits (786), Expect = 2e-83
 Identities = 175/505 (34%), Positives = 290/505 (57%), Gaps = 12/505 (2%)

Query: 31  VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90
           +G+ LG T +CV V+K+GR  ++AND G+R+TP+ VA++ E E ++G AAK     N  N
Sbjct: 4   IGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNISN 62

Query: 91  TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150
           TV   K+++GR+ +DP  Q+ I      V+EK  K   ++D G  +TK   PE+++ ++ 
Sbjct: 63  TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGE-ETKFVNPEDVARLIF 121

Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210
           +KMKETA + LG      V+TVP  F + Q+ A  +A   AG NV+R+I+EP+AA +AYG
Sbjct: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181

Query: 211 L--DKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIK 268
           +  D   G+ NILVF LGG +  +S++ +++G++ V++TN D ++GG  F + + ++   
Sbjct: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241

Query: 269 LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFE 328
            +++    DVR + RA+ KL    E AK +LS+   A   ++S YEG+DF   ++RA+FE
Sbjct: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301

Query: 329 ELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGI 388
            L   LF   ++ ++ +L+ +     DI+++VL GGS+RIPK+QQL+K+ F   E    I
Sbjct: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361

Query: 389 NPDEAVAYGAAVQAGVLSGDQD--TGDLVLLDVCP---LTLGIETVGGV-MTKLIPRNTV 442
            PDE +  GAA++AG+L G ++    D ++++      L  G++  G    T L P  T 
Sbjct: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421

Query: 443 VPTKKSQIFSTASDNQPTVTIKVYEGE-RPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTF 501
           +P ++      A  +  +V +++YE + +   K+        L  +     G+  I    
Sbjct: 422 LPARRQHTLQ-APGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480

Query: 502 EIDVNGILRVTAEDKGTGNKNKITI 526
            +  +G L VT  D+ TG    I+I
Sbjct: 481 TMKRDGSLHVTCTDQETGKCEAISI 505


>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
          Length = 840

 Score =  284 bits (727), Expect = 2e-76
 Identities = 194/603 (32%), Positives = 316/603 (52%), Gaps = 44/603 (7%)

Query: 29  TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88
           +VVGIDLG     V V + G +E IAN+  +R TP+ ++F P+  R IG AAK+Q+ SN 
Sbjct: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKN-RSIGAAAKSQVISNA 60

Query: 89  ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTK------PYIQVDIGGGQTKTFAP 142
           +NTV   KR  GR ++DP V+ +   L + +V+  T        Y++      + + F  
Sbjct: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYME------EERNFTT 114

Query: 143 EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEP 202
           E+++AM+L+K+KETAE+ L K V   VV+VP ++ DA+R++  DA  IAGLN +R++NE 
Sbjct: 115 EQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNET 174

Query: 203 TAAAIAYGLDKR------EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256
           TA A+AYG+ K+      E  +N++  D+G   + VS+   + G  +V+AT  DT LGG 
Sbjct: 175 TAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGR 234

Query: 257 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQ-HQARIEIESFYEG 315
            FD+ ++ HF + + KK   D++   RA+ +L +E EK K+ +S+      + IE F   
Sbjct: 235 KFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMND 294

Query: 316 EDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLV 375
            D S T+ R KF E+  DL      P++ VLE + LKK DI  + +VGG+TRIP +++ +
Sbjct: 295 VDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKI 354

Query: 376 KEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIE-----TVG 430
            +FF GKE S  +N DEAV  G A+Q  +LS      +  + DV P  + +        G
Sbjct: 355 SKFF-GKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEG 413

Query: 431 GVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPA 490
               ++  +N   P  K   F      +P      Y   + L   +  +  F +  + P 
Sbjct: 414 SSDCEVFSKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQ 470

Query: 491 PRG-VPQIEVTFEIDVNGILRVTAE---DKGTGNKNKITITNDQNRLTPEEIERMVNDAE 546
             G   +++V   ++V+GI  V++    +     +N+  +  DQN    +E E+M  D E
Sbjct: 471 SDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQE 527

Query: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKL-----GGKLSSEDKETMEKAVEEK 601
           +   E+++ +   + + E E    S   Q G K+K        K +     T++  +E +
Sbjct: 528 EPHVEEQQQQTPAENKAESEEMETS---QAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQ 584

Query: 602 IEW 604
           + W
Sbjct: 585 LLW 587



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 5/113 (4%)

Query: 536 EEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQI-GDKEKLGGKLSSEDKETM 594
           E +   + +  K   +DK  KER D +N +E Y Y +++++ G+ EK    +S +D+ + 
Sbjct: 592 EMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKF---VSEDDRNSF 648

Query: 595 EKAVEEKIEWL-ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEE 646
              +E+   WL E  +D   + +  K  EL+ + QPI  +   S   P   EE
Sbjct: 649 TLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEE 701



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 14/118 (11%)

Query: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEW-- 604
           +F E +++ K   +   +++ Y   + +   +KE     L + D   +EK+  E +EW  
Sbjct: 688 RFQESEERPKLFEELGKQIQQYM-KIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMN 746

Query: 605 ----LESHQDADIE------DFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKD 652
               L++ Q   ++      + +AK KEL     PIISK       PP  E+  AE++
Sbjct: 747 NKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV-EPPKEEQKNAEQN 803


>gi|48928056 heat shock protein 70kDa family member 13 precursor
           [Homo sapiens]
          Length = 471

 Score =  283 bits (723), Expect = 5e-76
 Identities = 170/449 (37%), Positives = 262/449 (58%), Gaps = 53/449 (11%)

Query: 5   LVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVF--KNGRVEIIANDQGNRIT 62
           L +A+L LL A    ++        V+GIDLGTTY  VGVF    G+V++I ++ G+   
Sbjct: 8   LGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISI 67

Query: 63  PSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEK 122
           PS V+FT + +  +G  +     SNP+NT++DAKR IG+ +    ++ +I   PFKV+ K
Sbjct: 68  PSMVSFT-DNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNK 126

Query: 123 KTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQ 182
                ++  +   +T T +PE + + +L K+KE AEAYLG  V +AV++VPA F+  QR 
Sbjct: 127 NGM--VEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRN 184

Query: 183 ATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVF 242
           +T +A  +AGL ++R+INEPTAAA+AYGL K +   ++LV DLGGGT DVSLL    G+F
Sbjct: 185 STIEAANLAGLKILRVINEPTAAAMAYGLHKAD-VFHVLVIDLGGGTLDVSLLNKQGGMF 243

Query: 243 EVVATNGDTHLGGEDFDQRVMEHFIK-LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSS 301
              A +G+  LGG+DF+QR++++  K +Y+       RK+   + +LR+ VE  K  L+ 
Sbjct: 244 LTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEE--IHRLRQAVEMVKLNLTL 301

Query: 302 QHQARIEIESFYEGED-------------------------------------------F 318
              A++ +    E +D                                           F
Sbjct: 302 HQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLF 361

Query: 319 SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378
              ++R  F+ LN DLF+  + P+Q+VL++  L+K++IDE+VLVGGSTRIP+I+Q+++EF
Sbjct: 362 ETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEF 421

Query: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSG 407
           F GK+P+  ++PD AV  G A+QAG+  G
Sbjct: 422 F-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449


>gi|42544159 heat shock 105kD [Homo sapiens]
          Length = 858

 Score =  263 bits (671), Expect = 5e-70
 Identities = 184/595 (30%), Positives = 310/595 (52%), Gaps = 30/595 (5%)

Query: 29  TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88
           +VVG+D+G+    + V + G +E IAN+  +R TPS ++F  +  R IG AAKNQ  ++ 
Sbjct: 2   SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKN-RTIGVAAKNQQITHA 60

Query: 89  ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAM 148
            NTV + KR  GR +NDP +Q++ + L + +V  K        +  G+   F+ E+I+AM
Sbjct: 61  NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120

Query: 149 VLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIA 208
           +LTK+KETAE  L K VT  V++VP++F DA+R++  DA  I GLN +R++N+ TA A+ 
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180

Query: 209 YGLDKR-----EGEKNILVF-DLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRV 262
           YG+ K+     + +  I+VF D+G   F VS    + G  +V+ T  D  LGG++FD+++
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240

Query: 263 MEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQH-QARIEIESFYEGEDFSET 321
           +EHF   +K K   D +   RA+ +L +E EK K+ +SS      + IE F   +D S  
Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300

Query: 322 LTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNG 381
           + R++FEEL  +L +    P+  +LE + LK  D+  + +VGG+TRIP +++ + +FF G
Sbjct: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-G 359

Query: 382 KEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGI------ETVGGVMTK 435
           K+ S  +N DEAVA G A+Q  +LS      +  + D  P  + +      E   GV  +
Sbjct: 360 KDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HE 418

Query: 436 LIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRG-V 494
           +  RN   P  K   F       P      Y   + +      +G F +  +     G  
Sbjct: 419 VFSRNHAAPFSKVLTFLRRG---PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEK 475

Query: 495 PQIEVTFEIDVNGILRVTAE---DKGTGNKNKITITNDQ---NRLTPEEIERMVNDAEKF 548
            +++V   ++ +GI  ++     +K    +N+++   D    N+  PE  +   N  +  
Sbjct: 476 SRVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDN 535

Query: 549 AEEDKKLKERIDTRNELES----YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE 599
           +E   + + + D +   +S       S +N+I D +K   K   +  E  +  ++
Sbjct: 536 SEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIK 590



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 5/102 (4%)

Query: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQI-GDKEKLGGKLSSEDKETMEKAVEEKIEWL 605
           K   +DK  KER D +N +E Y Y  ++++ G  EK    +  +D +   + + E  +WL
Sbjct: 620 KMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKF---ICEQDHQNFLRLLTETEDWL 676

Query: 606 -ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEE 646
            E  +D   + +  K +EL +I  P+  +   +   P   EE
Sbjct: 677 YEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEE 718



 Score = 33.9 bits (76), Expect = 0.49
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 15/97 (15%)

Query: 549 AEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESH 608
           AEE  K+ E +  R  L+ YA  +     +K++    +   + + +EK+V E +EW+ + 
Sbjct: 709 AEERPKMFEELGQR--LQHYA-KIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNV 765

Query: 609 QDAD------------IEDFKAKKKELEEIVQPIISK 633
            +A              ++ K K KEL    +P++++
Sbjct: 766 MNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQ 802


>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
          Length = 839

 Score =  252 bits (643), Expect = 9e-67
 Identities = 173/596 (29%), Positives = 314/596 (52%), Gaps = 33/596 (5%)

Query: 29  TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88
           +VVGIDLG     + V ++G +E IAN+  +R TP+ ++      R IG+AAK+Q+ +N 
Sbjct: 2   SVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSR-TRAIGNAAKSQIVTNV 60

Query: 89  ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGG-GQTKTFAPEEISA 147
            NT+   K+L GR+++DP VQ +   LP+++ +K       V +    + + FA E+++ 
Sbjct: 61  RNTIHGFKKLHGRSFDDPIVQTERIRLPYEL-QKMPNGSAGVKVRYLEEERPFAIEQVTG 119

Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
           M+L K+KET+E  L K V   V+++P++F DA+R++   A  +AGLN +R++NE TA A+
Sbjct: 120 MLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVAL 179

Query: 208 AYGLDKR------EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQR 261
           AYG+ K+      E  +N++  D+G   + V +   + G  +V+AT  D +LGG +FD+ 
Sbjct: 180 AYGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEA 239

Query: 262 VMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQ-HQARIEIESFYEGEDFSE 320
           ++++F   +K K   +V++++RA+ +L +E EK K+ +S+      + IE F    D S 
Sbjct: 240 LVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSS 299

Query: 321 TLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFN 380
            + RA+FE+L   L      P++ V+E ++L++ DI  I +VGG+TRIP +++ + +FF 
Sbjct: 300 KMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL 359

Query: 381 GKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCP--LTLGIETV---GGVMTK 435
            K+ S  +N DEAVA G A+Q  +LS      +  + D+ P  +TL  +T    G    +
Sbjct: 360 -KDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECE 418

Query: 436 LIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRG-V 494
           +  +N   P  K     T    +P      Y     +   +  +G+F +  + P   G  
Sbjct: 419 VFCKNHPAPFSK---VITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDS 475

Query: 495 PQIEVTFEIDVNGILRVTAED-------KGTGNKNKITITNDQNRLTPEEIERMVNDAEK 547
            +++V   ++++GI  V +         +G  +   +           + +++M  D E 
Sbjct: 476 SKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQE- 534

Query: 548 FAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIE 603
             E  +K         E++      K+ + DK+    +L+   K+   K+++  I+
Sbjct: 535 --EGHQKCHAEHTPEEEIDHTGAKTKSAVSDKQ---DRLNQTLKKGKVKSIDLPIQ 585



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 6/125 (4%)

Query: 532 RLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGD-KEKLGGKLSSED 590
           +L  + +   + +  K   +DK  KER D +N +E Y Y  ++++G   EK    ++ ED
Sbjct: 591 QLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKF---ITPED 647

Query: 591 KETMEKAVEEKIEWL-ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTA 649
              +   +E+   WL E  +D   + +  K +EL++  QPI  K Y      P    D  
Sbjct: 648 LSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMK-YMEHEERPKALNDLG 706

Query: 650 EKDEL 654
           +K +L
Sbjct: 707 KKIQL 711



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 45/146 (30%)

Query: 533 LTPEEIERM---VNDAEKFAEEDKKLKER---IDTRNELESYAYSLK------------- 573
           +TPE++ ++   + D E +  ED + + +   +D   EL+ Y   ++             
Sbjct: 643 ITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKAL 702

Query: 574 NQIGDKEKLGGK--------------LSSEDKETMEKAVEEKIEWLESHQDAD------- 612
           N +G K +L  K              L   + E +EK + + + WL S  +A        
Sbjct: 703 NDLGKKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQ 762

Query: 613 -----IEDFKAKKKELEEIVQPIISK 633
                + +  AK KEL+    PII K
Sbjct: 763 DPVVKVSEIVAKSKELDNFCNPIIYK 788


>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  207 bits (526), Expect = 3e-53
 Identities = 128/400 (32%), Positives = 213/400 (53%), Gaps = 22/400 (5%)

Query: 26  DVGTVVGIDLGTTYSCVGVFKNG-RVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 84
           D   V+ +DLG+    V + K G  +EI+ N +  R TP  V    E ER  GD+A +  
Sbjct: 31  DTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMA 89

Query: 85  TSNPENTVFDAKRLIGRTWNDPSVQ-QDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPE 143
             NP+ T+   + L+G+  ++P V     +F   ++     +  +   I       F+PE
Sbjct: 90  IKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISS--QLQFSPE 147

Query: 144 EISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPT 203
           E+  MVL   +  AE +  + +  AV+TVP +FN A+R+A   A  +AGL V+++IN+ T
Sbjct: 148 EVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNT 207

Query: 204 AAAIAYGLDKREG----EKNILVFDLGGGTFDVSLLTID---------NGVFEVVATNGD 250
           A A++YG+ +R+      +NI+ +D+G G+   +++T               ++     D
Sbjct: 208 ATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFD 267

Query: 251 THLGGEDFDQRVMEHFIKLY----KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQAR 306
             LGG + + R+ E    L+    K +  KDVR++ RA+ KL RE  + K  LS+     
Sbjct: 268 RTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHM 327

Query: 307 IEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGST 366
            +IE   +  DF   +TR +FEEL  DLF     PVQ+ L+ +++   +I++++LVGG+T
Sbjct: 328 AQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGAT 387

Query: 367 RIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLS 406
           R+P++Q+++ +    +E  + IN DEA A GA  QA  LS
Sbjct: 388 RVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427


>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  207 bits (526), Expect = 3e-53
 Identities = 128/400 (32%), Positives = 213/400 (53%), Gaps = 22/400 (5%)

Query: 26  DVGTVVGIDLGTTYSCVGVFKNG-RVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 84
           D   V+ +DLG+    V + K G  +EI+ N +  R TP  V    E ER  GD+A +  
Sbjct: 31  DTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMA 89

Query: 85  TSNPENTVFDAKRLIGRTWNDPSVQ-QDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPE 143
             NP+ T+   + L+G+  ++P V     +F   ++     +  +   I       F+PE
Sbjct: 90  IKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISS--QLQFSPE 147

Query: 144 EISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPT 203
           E+  MVL   +  AE +  + +  AV+TVP +FN A+R+A   A  +AGL V+++IN+ T
Sbjct: 148 EVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNT 207

Query: 204 AAAIAYGLDKREG----EKNILVFDLGGGTFDVSLLTID---------NGVFEVVATNGD 250
           A A++YG+ +R+      +NI+ +D+G G+   +++T               ++     D
Sbjct: 208 ATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFD 267

Query: 251 THLGGEDFDQRVMEHFIKLY----KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQAR 306
             LGG + + R+ E    L+    K +  KDVR++ RA+ KL RE  + K  LS+     
Sbjct: 268 RTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHM 327

Query: 307 IEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGST 366
            +IE   +  DF   +TR +FEEL  DLF     PVQ+ L+ +++   +I++++LVGG+T
Sbjct: 328 AQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGAT 387

Query: 367 RIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLS 406
           R+P++Q+++ +    +E  + IN DEA A GA  QA  LS
Sbjct: 388 RVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427


>gi|38348298 ankyrin repeat domain 45 [Homo sapiens]
          Length = 266

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 30/75 (40%), Positives = 44/75 (58%)

Query: 560 DTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAK 619
           D R  L+ Y   +   + D EK  GKL  EDK T+  A   K EWLE+H +A I +   +
Sbjct: 166 DARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSACRAKNEWLETHTEASINELFEQ 225

Query: 620 KKELEEIVQPIISKL 634
           +++LE+IV PI +K+
Sbjct: 226 RQQLEDIVTPIFTKM 240


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 8/128 (6%)

Query: 529 DQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSS 588
           +Q     E+ E+M    EK  E++KK++E+ +   E E      + ++G++E   GK+  
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE---GKMCE 478

Query: 589 EDKETMEKAVEEKIEWLES---HQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGE 645
           ++ +  E+  EEK+   E     Q+  I + + K +E EE++Q    K++         E
Sbjct: 479 QEAKMQEQ--EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536

Query: 646 EDTAEKDE 653
           E   E++E
Sbjct: 537 EKMQEQEE 544



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 14/137 (10%)

Query: 494 VPQIEVTFEIDVNG--ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEE 551
           +PQ ++  E D  G  +  V+A+ +    +N++      NRL  ++ E+M    EK  E 
Sbjct: 246 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW-----NRLNQQQEEKMWRQEEKIQER 300

Query: 552 DKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLES--HQ 609
           ++K++E+ +   E E      +  + +KE+   K+  +++   EK  EEKI  LE   H+
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEE---KMRRQEEMMWEK--EEKIRELEEKMHE 355

Query: 610 DADIEDFKAKKKELEEI 626
              I + + K++E E+I
Sbjct: 356 QEKIREQEEKRQEEEKI 372



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/100 (22%), Positives = 52/100 (52%), Gaps = 9/100 (9%)

Query: 529 DQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSS 588
           +Q     E+ E+M    EK  E++KK++E+ +   E E      + ++ ++E+   K+  
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE---KMCE 534

Query: 589 EDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQ 628
           ++++  E+  EEK+      Q+  + + + + ++ EE +Q
Sbjct: 535 QEEKMQEQ--EEKMR----RQEEKMREQEVRLRQQEEKMQ 568


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 21/129 (16%)

Query: 516 KGTGNKNKITITNDQNRL---------------TPEEIERMVNDAEKFAEEDKKLKERID 560
           KG+  KNK+ +  DQ RL                 EE +R   +A+K  EE+K+LKE+ +
Sbjct: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEK-E 385

Query: 561 TRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIED-FKAK 619
            R + E      + +  +K++L  +   E +E +E  +EEK +  E  +  + E   KA+
Sbjct: 386 RREKREKD----EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441

Query: 620 KKELEEIVQ 628
           K E+    Q
Sbjct: 442 KAEITRFFQ 450


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 31/133 (23%), Positives = 64/133 (48%), Gaps = 10/133 (7%)

Query: 528 NDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLS 587
           +DQ     E+ E+M    EK  E+++K++E+ +   E E      + ++G++E+   K+ 
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE---KMQ 561

Query: 588 SEDK-ETMEKAVEEKIEWLES------HQDADIEDFKAKKKELEEIVQPIISKLYGSAGP 640
            ++K    E+ + E+ E +         Q+  I + + K +E EE++Q    K++     
Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621

Query: 641 PPTGEEDTAEKDE 653
               EE   E++E
Sbjct: 622 MCEQEEKMQEQEE 634



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 34/142 (23%), Positives = 69/142 (48%), Gaps = 16/142 (11%)

Query: 494 VPQIEVTFEIDVNG--ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEE 551
           +PQ ++  E D  G  +  V+A+ +    +N++      NRL  ++ E+M    EK  E 
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW-----NRLNQQQEEKMWRQEEKIQEW 312

Query: 552 DKKLKERIDTRNELESYAYSLKNQIGDKEKL----GGKLSSEDKETMEKAVEEKIEWLES 607
           ++K++E+ +   E E      + ++  +E++      K+  +++   EK  EEK+  LE 
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRLEE 370

Query: 608 ---HQDADIEDFKAKKKELEEI 626
               ++  I + + K  E E+I
Sbjct: 371 MMWEKEEKIRELEEKMHEQEKI 392


>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
          Length = 728

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 11/134 (8%)

Query: 521 KNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKN-QIGDK 579
           K K+    +  R   +EIER+       AE +KK+KE  ++R  L+      +  ++ DK
Sbjct: 599 KEKLREATEAKRNLRKEIERLR------AENEKKMKEANESRLRLKRELEQARQARVCDK 652

Query: 580 EKLGGKLSSEDKETMEKAVEEKIEWLESHQD---ADIEDFKAKKKELEEIVQPIISKLYG 636
               G+L ++    +E  ++ K++  E+ ++   AD+   +  ++ LE++V+ +  +L+ 
Sbjct: 653 GCEAGRLRAKYSAQIED-LQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWP 711

Query: 637 SAGPPPTGEEDTAE 650
            A P   G E  AE
Sbjct: 712 RARPEAAGSEGAAE 725


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 27/110 (24%), Positives = 61/110 (55%), Gaps = 4/110 (3%)

Query: 529 DQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSS 588
           DQ+RL  EE +++  +A K  ++ ++++E      +LE Y  + K  + +++KL G+L+ 
Sbjct: 403 DQDRLDLEERKKVETEA-KIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461

Query: 589 E---DKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY 635
           E    K  +++  +E  + +E   DA I+  ++ +++ +  +   I +LY
Sbjct: 462 EVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLY 511


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 35/132 (26%), Positives = 69/132 (52%), Gaps = 12/132 (9%)

Query: 510  RVTAEDKGTGNKNKITITNDQNRLTPEE---IERMVND-AEKFAEEDKKLKERIDTRNEL 565
            +VTAE K    +++I + +DQN    +E   +E  ++D     AEE++K K     +N+ 
Sbjct: 973  KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1032

Query: 566  ESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE-EKIEWLESHQD--ADIEDFKAKKKE 622
            ES    L+ ++  +EK     S ++ E +++ +E +  ++ E   D  A I + K +  +
Sbjct: 1033 ESMISELEVRLKKEEK-----SRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087

Query: 623  LEEIVQPIISKL 634
             EE +Q  +++L
Sbjct: 1088 KEEELQAALARL 1099



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 26/105 (24%), Positives = 56/105 (53%), Gaps = 9/105 (8%)

Query: 526 ITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGK 585
           +T ++N L     E++  + E +AE ++        + ELE   + ++ ++ ++E  G +
Sbjct: 885 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 940

Query: 586 LSSEDKETMEKA--VEEKIEWLE-SHQDADIEDF--KAKKKELEE 625
           L +E K+  ++   +EE++E  E + Q   +E    +AK K+LE+
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 985


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 35/132 (26%), Positives = 69/132 (52%), Gaps = 12/132 (9%)

Query: 510  RVTAEDKGTGNKNKITITNDQNRLTPEE---IERMVND-AEKFAEEDKKLKERIDTRNEL 565
            +VTAE K    +++I + +DQN    +E   +E  ++D     AEE++K K     +N+ 
Sbjct: 980  KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1039

Query: 566  ESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE-EKIEWLESHQD--ADIEDFKAKKKE 622
            ES    L+ ++  +EK     S ++ E +++ +E +  ++ E   D  A I + K +  +
Sbjct: 1040 ESMISELEVRLKKEEK-----SRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094

Query: 623  LEEIVQPIISKL 634
             EE +Q  +++L
Sbjct: 1095 KEEELQAALARL 1106



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 26/105 (24%), Positives = 56/105 (53%), Gaps = 9/105 (8%)

Query: 526 ITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGK 585
           +T ++N L     E++  + E +AE ++        + ELE   + ++ ++ ++E  G +
Sbjct: 892 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 947

Query: 586 LSSEDKETMEKA--VEEKIEWLE-SHQDADIEDF--KAKKKELEE 625
           L +E K+  ++   +EE++E  E + Q   +E    +AK K+LE+
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 992


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 35/132 (26%), Positives = 69/132 (52%), Gaps = 12/132 (9%)

Query: 510  RVTAEDKGTGNKNKITITNDQNRLTPEE---IERMVND-AEKFAEEDKKLKERIDTRNEL 565
            +VTAE K    +++I + +DQN    +E   +E  ++D     AEE++K K     +N+ 
Sbjct: 980  KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1039

Query: 566  ESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE-EKIEWLESHQD--ADIEDFKAKKKE 622
            ES    L+ ++  +EK     S ++ E +++ +E +  ++ E   D  A I + K +  +
Sbjct: 1040 ESMISELEVRLKKEEK-----SRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094

Query: 623  LEEIVQPIISKL 634
             EE +Q  +++L
Sbjct: 1095 KEEELQAALARL 1106



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 26/105 (24%), Positives = 56/105 (53%), Gaps = 9/105 (8%)

Query: 526 ITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGK 585
           +T ++N L     E++  + E +AE ++        + ELE   + ++ ++ ++E  G +
Sbjct: 892 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 947

Query: 586 LSSEDKETMEKA--VEEKIEWLE-SHQDADIEDF--KAKKKELEE 625
           L +E K+  ++   +EE++E  E + Q   +E    +AK K+LE+
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 992


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 35/132 (26%), Positives = 69/132 (52%), Gaps = 12/132 (9%)

Query: 510  RVTAEDKGTGNKNKITITNDQNRLTPEE---IERMVND-AEKFAEEDKKLKERIDTRNEL 565
            +VTAE K    +++I + +DQN    +E   +E  ++D     AEE++K K     +N+ 
Sbjct: 973  KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1032

Query: 566  ESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE-EKIEWLESHQD--ADIEDFKAKKKE 622
            ES    L+ ++  +EK     S ++ E +++ +E +  ++ E   D  A I + K +  +
Sbjct: 1033 ESMISELEVRLKKEEK-----SRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087

Query: 623  LEEIVQPIISKL 634
             EE +Q  +++L
Sbjct: 1088 KEEELQAALARL 1099



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 26/105 (24%), Positives = 56/105 (53%), Gaps = 9/105 (8%)

Query: 526 ITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGK 585
           +T ++N L     E++  + E +AE ++        + ELE   + ++ ++ ++E  G +
Sbjct: 885 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 940

Query: 586 LSSEDKETMEKA--VEEKIEWLE-SHQDADIEDF--KAKKKELEE 625
           L +E K+  ++   +EE++E  E + Q   +E    +AK K+LE+
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 985


>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
          Length = 860

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 27/130 (20%)

Query: 514 EDKGTGNKNKITITNDQNRLTPEE---------------IERMVNDAEKFAEEDKKLKER 558
           E KG     +I    D  +LTPEE               ++    D  K  E  + LKER
Sbjct: 434 EPKGLKTLKEIRNAFDLFKLTPEEKNDVSENNRKREEIPLDFKTIDDHKTKENKQSLKER 493

Query: 559 IDTRNELESYAYSLKNQIGDKEKLGGKLSSED-----KETMEKAVEEKIEWL-----ESH 608
            +TR+E +++AY      GD+E L     +++     ++ +   ++ ++EW+     + H
Sbjct: 494 RNTRDETDTWAYIAAE--GDQEVLDSVCQADENSDGRQQILSLGMDLQLEWMKLEDFQKH 551

Query: 609 QDADIEDFKA 618
            D   E+F A
Sbjct: 552 LDGKDENFAA 561


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 2/117 (1%)

Query: 510 RVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYA 569
           R+ AE        +  I  ++     E   R   + E+  EE+K+  E      E E  A
Sbjct: 279 RIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRA 338

Query: 570 YSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIE-WLESHQDADIEDFKAKKKELEE 625
              + +I ++EK   +     KE  ++A EE+     E  + A +E+ K + K+LEE
Sbjct: 339 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK-RNKQLEE 394



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 30/136 (22%), Positives = 60/136 (44%), Gaps = 11/136 (8%)

Query: 529 DQNRLTPEEI--ERMVNDAEKFAEEDKKL--KERIDTRNELESYAY-------SLKNQIG 577
           ++ RL  E I  +R  +D E+ A E ++   +ER+  + E ES          + +N + 
Sbjct: 16  EEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVP 75

Query: 578 DKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGS 637
           D+E      +++ +   E A  E++   E  +   +++   ++KE +  +      L   
Sbjct: 76  DEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSR 135

Query: 638 AGPPPTGEEDTAEKDE 653
                T E +T EK+E
Sbjct: 136 RMQNDTAENETTEKEE 151


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 20/125 (16%)

Query: 271  KKKTGKDVRK----DNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326
            KKK   D+ +       AVQ+ R   EKAK+A++    A +  E   + +D S  L R K
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD---AAMMAEELKKEQDTSAHLERMK 1783

Query: 327  FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386
                         K +++ ++D   +  + ++I L GG  ++ K++  V+E  N  E  +
Sbjct: 1784 -------------KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ 1830

Query: 387  GINPD 391
              N +
Sbjct: 1831 KRNAE 1835



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 30/98 (30%), Positives = 52/98 (53%), Gaps = 14/98 (14%)

Query: 532  RLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDK 591
            +LT E I  + ND ++    D++LK++    N L +       +I D++ LG +L  + K
Sbjct: 1060 KLTQESIMDLENDKQQL---DERLKKKDFELNALNA-------RIEDEQALGSQLQKKLK 1109

Query: 592  ETMEKAVEEKIEWLESHQDADIEDFKAK---KKELEEI 626
            E ++  +EE  E LE+ + A  +  K +    +ELEEI
Sbjct: 1110 E-LQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146



 Score = 29.6 bits (65), Expect = 9.2
 Identities = 20/83 (24%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 276  KDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFE-ELNMDL 334
            K++ ++   + ++  ++ K K+AL   HQ    ++     ED   TLT+AK + E  +D 
Sbjct: 976  KNLTEEMAGLDEIIAKLTKEKKALQEAHQQ--ALDDLQAEEDKVNTLTKAKVKLEQQVDD 1033

Query: 335  FRSTMKPVQKVLEDSDLKKSDID 357
               +++  +KV  D +  K  ++
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLE 1056


>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
          Length = 761

 Score = 37.4 bits (85), Expect = 0.044
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 25/132 (18%)

Query: 519 GNKNKITITNDQNRLTPEEIERMVNDAEK-----------FAEEDKKLKERIDTRNELES 567
           G +N+I I   +   T EE+   + + +            F  E++KL++++    EL  
Sbjct: 331 GERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQ 390

Query: 568 YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLE---SHQDADIEDFKAKKKELE 624
                +N++    KL  KL+ E+   +EK  EEK+  ++   SH   ++E ++ + K+LE
Sbjct: 391 -----ENEM----KLHRKLTVEENYRLEK--EEKLSKVDEKISHATEELETYRKRAKDLE 439

Query: 625 EIVQPIISKLYG 636
           E ++  I    G
Sbjct: 440 EELERTIHSYQG 451


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,867,289
Number of Sequences: 37866
Number of extensions: 1098942
Number of successful extensions: 4339
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 3808
Number of HSP's gapped (non-prelim): 657
length of query: 654
length of database: 18,247,518
effective HSP length: 109
effective length of query: 545
effective length of database: 14,120,124
effective search space: 7695467580
effective search space used: 7695467580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.