Guide to the Human Genome
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Search of human proteins with 16506828

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16506828 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform a precursor [Homo sapiens]
         (595 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16506828 sialic acid binding immunoglobulin-like lectin-like ...  1224   0.0  
gi|16506826 sialic acid binding immunoglobulin-like lectin-like ...   931   0.0  
gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ...   629   e-180
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]       627   e-180
gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens]       597   e-171
gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec...   418   e-117
gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec...   390   e-108
gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec...   364   e-100
gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom...   354   1e-97
gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens]     332   8e-91
gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens]        311   1e-84
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho...   288   1e-77
gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens]          287   2e-77
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]      272   6e-73
gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho...   239   7e-63
gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens]          149   7e-36
gi|11225258 myelin associated glycoprotein isoform a precursor [...   118   1e-26
gi|18104957 myelin associated glycoprotein isoform b precursor [...   118   1e-26
gi|13489095 sialoadhesin precursor [Homo sapiens]                      96   1e-19
gi|157168355 CD22 molecule [Homo sapiens]                              86   1e-16
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             59   1e-08
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]      57   4e-08
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]       57   6e-08
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]        57   6e-08
gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens]       56   1e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    55   2e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    55   2e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    55   2e-07
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...    54   3e-07
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   54   3e-07

>gi|16506828 sialic acid binding immunoglobulin-like lectin-like
           protein 1 isoform a precursor [Homo sapiens]
          Length = 595

 Score = 1224 bits (3167), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60
           MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH
Sbjct: 1   MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60

Query: 61  GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120
           GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV
Sbjct: 61  GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120

Query: 121 FCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNW 180
           FCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNW
Sbjct: 121 FCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNW 180

Query: 181 TASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARK 240
           TASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARK
Sbjct: 181 TASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARK 240

Query: 241 GDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACE 300
           GDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACE
Sbjct: 241 GDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACE 300

Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360
           QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN
Sbjct: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360

Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420
           ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL
Sbjct: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420

Query: 421 SPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480
           SPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG
Sbjct: 421 SPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480

Query: 481 AFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESP 540
           AFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESP
Sbjct: 481 AFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESP 540

Query: 541 ADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 595
           ADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK
Sbjct: 541 ADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 595


>gi|16506826 sialic acid binding immunoglobulin-like lectin-like
           protein 1 isoform b precursor [Homo sapiens]
          Length = 477

 Score =  931 bits (2407), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 142 TASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDI 201
           TASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDI
Sbjct: 24  TASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDI 83

Query: 202 PVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY 261
           PVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY
Sbjct: 84  PVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY 143

Query: 262 DKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTI 321
           DKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTI
Sbjct: 144 DKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTI 203

Query: 322 TRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAST 381
           TRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAST
Sbjct: 204 TRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAST 263

Query: 382 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDE 441
           TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDE
Sbjct: 264 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDE 323

Query: 442 GEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVV 501
           GEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVV
Sbjct: 324 GEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVV 383

Query: 502 VRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEG 561
           VRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEG
Sbjct: 384 VRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEG 443

Query: 562 EIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 595
           EIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK
Sbjct: 444 EIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 477



 Score =  161 bits (408), Expect = 1e-39
 Identities = 129/370 (34%), Positives = 183/370 (49%), Gaps = 44/370 (11%)

Query: 24  YLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPAR 83
           Y L + +SVTVQEGLCVSV CS  YP   WTAS PV+G WF+ G  +  +IPVATN P+ 
Sbjct: 33  YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 92

Query: 84  AVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTA 143
            VQE+T  RF LLGDPQ  +C+LSIRD R+ D+G Y F VERG+ KWNY YD+LSV+VTA
Sbjct: 93  KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 152

Query: 144 SQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV 203
              L       +P   T++ G   ++ CSV +     T   P   +W   GA +    P 
Sbjct: 153 ---LTHMPTFSIPG--TLESGHPRNLTCSVPWACEQGT---PPTITWM--GASVSSLDPT 202

Query: 204 ATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDK 263
            T +              L+  PQ +  SL+ +    G +G    +  R     +Y    
Sbjct: 203 ITRS----------SMLSLIPQPQDHGTSLTCQVTLPG-AGVTMTRAVR--LNISYPPQN 249

Query: 264 LSVHV-----TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLD 318
           L++ V     TA T +   S    LE G   +L C+V    +   P  ++W   S+ +L 
Sbjct: 250 LTMTVFQGDGTASTTLRNGSALSVLE-GQSLHLVCAV----DSNPPARLSWTWGSL-TLS 303

Query: 319 PTITRSSMLSLIPQPQDH---GTSLTCQVTLPGAGVTMTRAVRLNISY-----PPQNLTM 370
           P  ++SS L ++  P+ H       TC+   P     ++ ++ L   Y     P   +T+
Sbjct: 304 P--SQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTL 361

Query: 371 TVFQGDGTAS 380
             F G G  +
Sbjct: 362 GAFGGAGATA 371


>gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo
           sapiens]
          Length = 467

 Score =  629 bits (1622), Expect = e-180
 Identities = 318/445 (71%), Positives = 356/445 (80%), Gaps = 3/445 (0%)

Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210
           Y L +  SVTVQEG+CV V CS  YP  + T S PV+G WF+ G DI W  PVATN P+ 
Sbjct: 26  YSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAW 85

Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 270
            VQE+T  RF LLGDPQT NC+LSIRDAR  D+G+Y+F++E+G+ KWNY YD+LSV+VTA
Sbjct: 86  AVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTA 145

Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330
           LTH P   IPGTLESG  +NLTCSVPWACEQGTPP I+WMG SVS L P+ TRSS+L+LI
Sbjct: 146 LTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLI 205

Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390
           PQPQ HGTSLTCQVTLPGAGVT  R ++LN+SYPPQNLT+TVFQG+GTAST L N S+LS
Sbjct: 206 PQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLS 265

Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450
           VLEGQSL LVCAVDSNPPARLSWTW SLTL PSQ SN  VLEL +VH+ DEGEFTCRAQN
Sbjct: 266 VLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQN 324

Query: 451 PLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA 510
            LGSQH+SL+LSLQ EYTGKMRP+SGV LGA GGAGATALVFL FC+IF+VVRSCRKKSA
Sbjct: 325 SLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSA 384

Query: 511 RPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSF 570
           RPA  VGD GM+DAN +RGSASQG L ES ADD+P HH     A  S EE EIQYA LSF
Sbjct: 385 RPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHSSGEEREIQYAPLSF 442

Query: 571 HKARPQYPQEQEAIGYEYSEINIPK 595
           HK  PQ    QEA   EYSEI IPK
Sbjct: 443 HKGEPQDLSGQEATNNEYSEIKIPK 467



 Score =  216 bits (549), Expect = 6e-56
 Identities = 120/200 (60%), Positives = 141/200 (70%), Gaps = 18/200 (9%)

Query: 3   LLLLLLPPLLCGRVGAKEQK----DYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDP 58
           +LLLLL PLL GR   + QK    DY LTMQ SVTVQEG+CV V CSFSYP +  T SDP
Sbjct: 1   MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60

Query: 59  VHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGT 118
           VHGYWFRAG+ +S   PVATNNPA AVQEETRDRFHLLGDPQ K+CTLSIRD R SDAG 
Sbjct: 61  VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120

Query: 119 YVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY--- 175
           Y F +E+GN+KWNYKYDQLSVNVTA   L  R  + +P   T++ G   ++ CSV +   
Sbjct: 121 YFFRMEKGNIKWNYKYDQLSVNVTA---LTHRPNILIPG--TLESGCFQNLTCSVPWACE 175

Query: 176 ----PHYNW--TASSPVYGS 189
               P  +W  T+ SP++ S
Sbjct: 176 QGTPPMISWMGTSVSPLHPS 195


>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
          Length = 499

 Score =  627 bits (1618), Expect = e-180
 Identities = 321/451 (71%), Positives = 354/451 (78%), Gaps = 6/451 (1%)

Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210
           Y L+V E VTVQEGLCV VPCS  YP   WT S PV+G WF+ G     D PVATN P  
Sbjct: 27  YLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDR 86

Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKW------NYIYDKL 264
           +VQ +T GRF LLGD  +N+CSLSIRDARK D G Y+F++ERGS KW      NY   +L
Sbjct: 87  EVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQL 146

Query: 265 SVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRS 324
           SV VTALTH P   I GTLESGH RNLTCSVPWAC+QGTPP I+W+GASVSS  PT  RS
Sbjct: 147 SVFVTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARS 206

Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384
           S+L+L P+PQDHGTSLTCQVTLPG GVT T  VRL++SYPP NLTMTVFQGD TAST L 
Sbjct: 207 SVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALG 266

Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444
           NGS+LSVLEGQSL LVCAV+SNPPARLSWT GSLTL PS+SSN G+LELPRVHV+DEGEF
Sbjct: 267 NGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEF 326

Query: 445 TCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRS 504
           TCRAQN  GSQHISLSLSLQNE TG  RP+S VTL A GGAGATAL FL FCIIF++VRS
Sbjct: 327 TCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRS 386

Query: 505 CRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQ 564
           CRKKSARPA GVGDTGMEDA A+RGSASQGPL ES  D +P    PPA+A  S EEGE+ 
Sbjct: 387 CRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPSSGEEGELH 446

Query: 565 YASLSFHKARPQYPQEQEAIGYEYSEINIPK 595
           YA+LSFHK +PQ PQ QEA   EYSEI I K
Sbjct: 447 YATLSFHKVKPQDPQGQEATDSEYSEIKIHK 477



 Score =  185 bits (469), Expect = 1e-46
 Identities = 133/345 (38%), Positives = 176/345 (51%), Gaps = 36/345 (10%)

Query: 2   LLLLLLLPPLLCGRVGAKEQKDY----LLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASD 57
           +LLLLLL PLL G  G +  + Y    LL +Q+ VTVQEGLCV V CSFSYPQ+GWT SD
Sbjct: 1   MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSD 60

Query: 58  PVHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAG 117
           PVHGYWFRAGD   ++ PVATNNP R VQ ET+ RF LLGD  + DC+LSIRD R+ D G
Sbjct: 61  PVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKG 120

Query: 118 TYVFCVERGNMKW------NYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPC 171
           +Y F +ERG+MKW      NYK  QLSV VTA       +R ++    T++ G   ++ C
Sbjct: 121 SYFFRLERGSMKWSYKSQLNYKTKQLSVFVTA-----LTHRPDILILGTLESGHSRNLTC 175

Query: 172 SVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNC 231
           SV +     T   P   SW       P      ++  +   +   HG  L         C
Sbjct: 176 SVPWACKQGT---PPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSL--------TC 224

Query: 232 SLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNL 291
            +++     G +     +++     WN          TA T +   S    LE G    L
Sbjct: 225 QVTLPGT--GVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLE-GQSLRL 281

Query: 292 TCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDH 336
            C+V        P  ++W   S+ +L P  +RSS   L+  P+ H
Sbjct: 282 VCAV----NSNPPARLSWTRGSL-TLCP--SRSSNPGLLELPRVH 319


>gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens]
          Length = 463

 Score =  597 bits (1540), Expect = e-171
 Identities = 304/445 (68%), Positives = 346/445 (77%), Gaps = 10/445 (2%)

Query: 153 LEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPV-YGSWFKEGADIPWDIPVATNTPSGK 211
           L +  SVTVQEGLCV VPCS  YP + W    PV +G WF+EGA+   D PVATN P+  
Sbjct: 23  LTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGYWFREGANTDQDAPVATNNPARA 82

Query: 212 VQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTAL 271
           V E+T  RF LLGDP T NC+LSIRDAR+ D+G+Y+F++E+GS KWNY + +LSV+VTAL
Sbjct: 83  VWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKWNYKHHRLSVNVTAL 142

Query: 272 THMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP 331
           TH P   IPGTLESG P+NLTCSVPWACEQGTPP I+W+G SVS LDP+ TRSS+L+LIP
Sbjct: 143 THRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWIGTSVSPLDPSTTRSSVLTLIP 202

Query: 332 QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSV 391
           QPQDHGTSLTCQVT PGA VT  + V LN+SYPPQNLTMTVFQGDGT ST L NGS+LS+
Sbjct: 203 QPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSL 262

Query: 392 LEGQSLHLVC---AVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRA 448
            EGQSL LVC   AVDSNPPARLS +W  LTL PSQ SN GVLELP VH++D  EFTCRA
Sbjct: 263 PEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRA 322

Query: 449 QNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKK 508
           QNPLGSQ + L++SLQ++ T      SGVT G  GGAGATALVFL FC+IFVVVRSCRKK
Sbjct: 323 QNPLGSQQVYLNVSLQSKAT------SGVTQGVVGGAGATALVFLSFCVIFVVVRSCRKK 376

Query: 509 SARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASL 568
           SARPA GVGDTG+EDANAVRGSASQGPL E  A+DSPP   PPA A  S  EGE+QYASL
Sbjct: 377 SARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARSSVGEGELQYASL 436

Query: 569 SFHKARPQYPQEQEAIGYEYSEINI 593
           SF   +P   + QEA   EYSEI I
Sbjct: 437 SFQMVKPWDSRGQEATDTEYSEIKI 461



 Score =  199 bits (506), Expect = 6e-51
 Identities = 108/189 (57%), Positives = 130/189 (68%), Gaps = 13/189 (6%)

Query: 4   LLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPV-HGY 62
           +LLLL PLL GR  A+ Q   LLTMQ SVTVQEGLCV V CSFSYP +GW    PV HGY
Sbjct: 1   MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGY 60

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           WFR G +  ++ PVATNNPARAV EETRDRFHLLGDP  K+CTLSIRD R SDAG Y F 
Sbjct: 61  WFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFR 120

Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175
           +E+G++KWNYK+ +LSVNVTA   L  R  + +P   T++ G   ++ CSV +       
Sbjct: 121 MEKGSIKWNYKHHRLSVNVTA---LTHRPNILIPG--TLESGCPQNLTCSVPWACEQGTP 175

Query: 176 PHYNWTASS 184
           P  +W  +S
Sbjct: 176 PMISWIGTS 184


>gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1
           precursor [Homo sapiens]
          Length = 453

 Score =  418 bits (1074), Expect = e-117
 Identities = 234/447 (52%), Positives = 292/447 (65%), Gaps = 24/447 (5%)

Query: 150 RYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPS 209
           R++LE PES+TVQEGLCV VPC +        AS   YG WF EGAD+P    VATN P 
Sbjct: 30  RFQLEGPESLTVQEGLCVLVPCRL---PTTLPASYYGYGYWFLEGADVP----VATNDPD 82

Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVT 269
            +VQE+T GRF LL DP+  NCSLSIRDAR+ D+  Y+F+++    K+ Y   KLSV V 
Sbjct: 83  EEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVM 142

Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSL 329
           ALTH P  SIPGTLESGHP NLTCSVPW CEQGTPP  +WM A+ +SL P  T+SS+L++
Sbjct: 143 ALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTI 202

Query: 330 IPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389
            P+PQDH T+LTCQVT PGAGVTM R ++LN+SY PQ + +++FQG+  A   L+N S+L
Sbjct: 203 TPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSL 262

Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449
            VLEGQ+L L+C  D NPPA LSW  G   L+ +  SN GVLELP+V   +EG+FTCRAQ
Sbjct: 263 PVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQ 322

Query: 450 NPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKS 509
           +PLGS  ISLSL +  +  G+    +G  LGA  GA  T LVFL  C IF  V++ RKK+
Sbjct: 323 HPLGSLQISLSLFVHWKPEGR----AGGVLGAVWGASITTLVFLCVCFIF-RVKTRRKKA 377

Query: 510 ARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATP-SPEEGEIQYASL 568
           A+P         +D N V  S S+G   +        H   PA A P S +E E+ YA L
Sbjct: 378 AQPV-----QNTDDVNPVMVSGSRGHQHQFQTGIVSDH---PAEAGPISEDEQELHYAVL 429

Query: 569 SFHKARPQYPQEQEAIGYEYSEINIPK 595
            FHK +PQ P+  +    EYSEI I K
Sbjct: 430 HFHKVQPQEPKVTDT---EYSEIKIHK 453



 Score =  112 bits (280), Expect = 1e-24
 Identities = 75/190 (39%), Positives = 106/190 (55%), Gaps = 21/190 (11%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           +L LLLP L  G +   +++ + L   +S+TVQEGLCV V C          AS   +GY
Sbjct: 12  MLPLLLPLLWAGALA--QERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGY 66

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           WF  G     ++PVATN+P   VQEETR RFHLL DP+ K+C+LSIRD R  D   Y F 
Sbjct: 67  WFLEG----ADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122

Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175
           ++   MK+ Y   +LSV V A   L  R  + +P   T++ G   ++ CSV +       
Sbjct: 123 LKSKWMKYGYTSSKLSVRVMA---LTHRPNISIPG--TLESGHPSNLTCSVPWVCEQGTP 177

Query: 176 PHYNWTASSP 185
           P ++W +++P
Sbjct: 178 PIFSWMSAAP 187


>gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2
           precursor [Homo sapiens]
          Length = 437

 Score =  390 bits (1002), Expect = e-108
 Identities = 227/447 (50%), Positives = 281/447 (62%), Gaps = 40/447 (8%)

Query: 150 RYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPS 209
           R++LE PES+TVQEGLCV VPC +        AS   YG WF EGAD+P    VATN P 
Sbjct: 30  RFQLEGPESLTVQEGLCVLVPCRL---PTTLPASYYGYGYWFLEGADVP----VATNDPD 82

Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVT 269
            +VQE+T GRF LL DP+  NCSLSIRDAR+ D+  Y+F+++    K+ Y   KLSV V 
Sbjct: 83  EEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVM 142

Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSL 329
           ALTH P  SIPGTLESGHP NLTCSVPW CEQGTPP  +WM A+ +SL P  T+SS+L++
Sbjct: 143 ALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTI 202

Query: 330 IPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389
            P+PQDH T+LTCQVT PGAGVTM R ++LN+S                +   L+N S+L
Sbjct: 203 TPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVS----------------SFKILQNTSSL 246

Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449
            VLEGQ+L L+C  D NPPA LSW  G   L+ +  SN GVLELP+V   +EG+FTCRAQ
Sbjct: 247 PVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQ 306

Query: 450 NPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKS 509
           +PLGS  ISLSL +  +  G+    +G  LGA  GA  T LVFL  C IF  V++ RKK+
Sbjct: 307 HPLGSLQISLSLFVHWKPEGR----AGGVLGAVWGASITTLVFLCVCFIF-RVKTRRKKA 361

Query: 510 ARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATP-SPEEGEIQYASL 568
           A+P         +D N V  S S+G   +        H   PA A P S +E E+ YA L
Sbjct: 362 AQPV-----QNTDDVNPVMVSGSRGHQHQFQTGIVSDH---PAEAGPISEDEQELHYAVL 413

Query: 569 SFHKARPQYPQEQEAIGYEYSEINIPK 595
            FHK +PQ P+  +    EYSEI I K
Sbjct: 414 HFHKVQPQEPKVTDT---EYSEIKIHK 437



 Score =  112 bits (280), Expect = 1e-24
 Identities = 75/190 (39%), Positives = 106/190 (55%), Gaps = 21/190 (11%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           +L LLLP L  G +   +++ + L   +S+TVQEGLCV V C          AS   +GY
Sbjct: 12  MLPLLLPLLWAGALA--QERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGY 66

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           WF  G     ++PVATN+P   VQEETR RFHLL DP+ K+C+LSIRD R  D   Y F 
Sbjct: 67  WFLEG----ADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122

Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175
           ++   MK+ Y   +LSV V A   L  R  + +P   T++ G   ++ CSV +       
Sbjct: 123 LKSKWMKYGYTSSKLSVRVMA---LTHRPNISIPG--TLESGHPSNLTCSVPWVCEQGTP 177

Query: 176 PHYNWTASSP 185
           P ++W +++P
Sbjct: 178 PIFSWMSAAP 187


>gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3
           precursor [Homo sapiens]
          Length = 353

 Score =  364 bits (934), Expect = e-100
 Identities = 183/312 (58%), Positives = 225/312 (72%), Gaps = 7/312 (2%)

Query: 150 RYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPS 209
           R++LE PES+TVQEGLCV VPC +        AS   YG WF EGAD+P    VATN P 
Sbjct: 30  RFQLEGPESLTVQEGLCVLVPCRL---PTTLPASYYGYGYWFLEGADVP----VATNDPD 82

Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVT 269
            +VQE+T GRF LL DP+  NCSLSIRDAR+ D+  Y+F+++    K+ Y   KLSV V 
Sbjct: 83  EEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVM 142

Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSL 329
           ALTH P  SIPGTLESGHP NLTCSVPW CEQGTPP  +WM A+ +SL P  T+SS+L++
Sbjct: 143 ALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTI 202

Query: 330 IPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389
            P+PQDH T+LTCQVT PGAGVTM R ++LN+SY PQ + +++FQG+  A   L+N S+L
Sbjct: 203 TPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSL 262

Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449
            VLEGQ+L L+C  D NPPA LSW  G   L+ +  SN GVLELP+V   +EG+FTCRAQ
Sbjct: 263 PVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQ 322

Query: 450 NPLGSQHISLSL 461
           +PLGS  ISLSL
Sbjct: 323 HPLGSLQISLSL 334



 Score =  112 bits (280), Expect = 1e-24
 Identities = 75/190 (39%), Positives = 106/190 (55%), Gaps = 21/190 (11%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           +L LLLP L  G +   +++ + L   +S+TVQEGLCV V C          AS   +GY
Sbjct: 12  MLPLLLPLLWAGALA--QERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGY 66

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           WF  G     ++PVATN+P   VQEETR RFHLL DP+ K+C+LSIRD R  D   Y F 
Sbjct: 67  WFLEG----ADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122

Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175
           ++   MK+ Y   +LSV V A   L  R  + +P   T++ G   ++ CSV +       
Sbjct: 123 LKSKWMKYGYTSSKLSVRVMA---LTHRPNISIPG--TLESGHPSNLTCSVPWVCEQGTP 177

Query: 176 PHYNWTASSP 185
           P ++W +++P
Sbjct: 178 PIFSWMSAAP 187


>gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo
           sapiens]
          Length = 374

 Score =  354 bits (908), Expect = 1e-97
 Identities = 220/445 (49%), Positives = 256/445 (57%), Gaps = 96/445 (21%)

Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210
           Y L +  SVTVQEG+CV V CS  YP  + T S PV+G WF+ G DI W  PVATN P+ 
Sbjct: 26  YSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAW 85

Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 270
            VQE+T  RF LLGDPQT NC+LSIRDAR  D+G+Y+F++E+G+ KWNY YD+LSV+VT 
Sbjct: 86  AVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVT- 144

Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330
                            P+NLT +V     QG     T +G            SS LS++
Sbjct: 145 ---------------DPPQNLTVTV----FQGEGTASTALG-----------NSSSLSVL 174

Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390
              +     L C V                 S PP  L+ T                   
Sbjct: 175 ---EGQSLRLVCAVD----------------SNPPARLSWT------------------- 196

Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450
               +SL L  +  SNP                      VLEL +VH+ DEGEFTCRAQN
Sbjct: 197 ---WRSLTLYPSQPSNPL---------------------VLEL-QVHLGDEGEFTCRAQN 231

Query: 451 PLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA 510
            LGSQH+SL+LSLQ EYTGKMRP+SGV LGA GGAGATALVFL FC+IF+VVRSCRKKSA
Sbjct: 232 SLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSA 291

Query: 511 RPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSF 570
           RPA  VGD GM+DAN +RGSASQG L ES ADD+P HH     A  S EE EIQYA LSF
Sbjct: 292 RPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHSSGEEREIQYAPLSF 349

Query: 571 HKARPQYPQEQEAIGYEYSEINIPK 595
           HK  PQ    QEA   EYSEI IPK
Sbjct: 350 HKGEPQDLSGQEATNNEYSEIKIPK 374



 Score =  208 bits (530), Expect = 1e-53
 Identities = 105/144 (72%), Positives = 115/144 (79%), Gaps = 4/144 (2%)

Query: 3   LLLLLLPPLLCGRVGAKEQK----DYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDP 58
           +LLLLL PLL GR   + QK    DY LTMQ SVTVQEG+CV V CSFSYP +  T SDP
Sbjct: 1   MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60

Query: 59  VHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGT 118
           VHGYWFRAG+ +S   PVATNNPA AVQEETRDRFHLLGDPQ K+CTLSIRD R SDAG 
Sbjct: 61  VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120

Query: 119 YVFCVERGNMKWNYKYDQLSVNVT 142
           Y F +E+GN+KWNYKYDQLSVNVT
Sbjct: 121 YFFRMEKGNIKWNYKYDQLSVNVT 144


>gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens]
          Length = 396

 Score =  332 bits (850), Expect = 8e-91
 Identities = 172/318 (54%), Positives = 218/318 (68%), Gaps = 5/318 (1%)

Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV-ATNTPS 209
           Y L+V +SVTVQEGLCV VPCS  YP  +W +S P+Y  WF++G +IP+   V ATN P 
Sbjct: 21  YELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDG-EIPYYAEVVATNNPD 79

Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHV 268
            +V+ +T GRF LLGD Q  NCSLSI DAR  D+G Y+F+VERG   K++Y  +KL++ V
Sbjct: 80  RRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEV 139

Query: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLS 328
           TAL   P       LESG P  L+CS+P +CE G P T +W G ++S LDP  TRSS L+
Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELT 199

Query: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF--QGDGTASTTLRNG 386
           L P+P+DHGT+LTCQV   GA VT  R V+LN+SY PQNL +++F   G GTA   L NG
Sbjct: 200 LTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNG 259

Query: 387 SALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTC 446
            ++ + EGQSL L C VDSNPPA LSW      L+PSQ+S  G LELP +  ++ GEFTC
Sbjct: 260 MSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTC 319

Query: 447 RAQNPLGSQHISLSLSLQ 464
           R Q+PLGSQH+S  LS+Q
Sbjct: 320 RVQHPLGSQHLSFILSVQ 337



 Score =  137 bits (346), Expect = 2e-32
 Identities = 80/157 (50%), Positives = 104/157 (66%), Gaps = 2/157 (1%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           +L LLL PLL G    +E+  Y L +QKSVTVQEGLCV V CSFSYP   W +S P++ Y
Sbjct: 1   MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           WFR G+       VATNNP R V+ ET+ RF LLGD Q K+C+LSI D R  D G+Y F 
Sbjct: 60  WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119

Query: 123 VERG-NMKWNYKYDQLSVNVTASQDLLSRYRLEVPES 158
           VERG ++K++Y+ ++L++ VTA  +    + LE  ES
Sbjct: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES 156


>gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens]
          Length = 551

 Score =  311 bits (797), Expect = 1e-84
 Identities = 168/315 (53%), Positives = 215/315 (68%), Gaps = 6/315 (1%)

Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV-ATNTPS 209
           Y L+V +SVTVQEGLCV VPCS  YP  +W +S P+Y  WF++G +IP+   V ATN P 
Sbjct: 21  YELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDG-EIPYYAEVVATNNPD 79

Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHV 268
            +V+ +T GRF LLGD Q  NCSLSI DAR  D+G Y+F+VERG   K++Y  +KL++ V
Sbjct: 80  RRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEV 139

Query: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLS 328
           TAL   P       LESG P  L+CS+P +CE G P T +W G ++S LDP  TRSS L+
Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELT 199

Query: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388
           L P+P+DHGT+LTCQ+   GA VT  R V+LN+SY PQ  T+T+F+ +G A   L+N S 
Sbjct: 200 LTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQ--TITIFR-NGIALEILQNTSY 256

Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRA 448
           L VLEGQ+L L+C   SNPPA LSW  GS  L+ +  SN G+LEL RV   +EG FTCRA
Sbjct: 257 LPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRA 316

Query: 449 QNPLGSQHISLSLSL 463
           Q+PLG   I L+LS+
Sbjct: 317 QHPLGFLQIFLNLSV 331



 Score =  194 bits (492), Expect = 3e-49
 Identities = 194/615 (31%), Positives = 283/615 (46%), Gaps = 86/615 (13%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           +L LLL PLL G    +E+  Y L +QKSVTVQEGLCV V CSFSYP   W +S P++ Y
Sbjct: 1   MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           WFR G+       VATNNP R V+ ET+ RF LLGD Q K+C+LSI D R  D G+Y F 
Sbjct: 60  WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119

Query: 123 VERG-NMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWT 181
           VERG ++K++Y+ ++L++ VTA  +    + LE  ES     G    + CS+     +  
Sbjct: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES-----GRPTRLSCSL---PGSCE 171

Query: 182 ASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKG 241
           A  P+  SW    A  P D P  T +              L   P+ +  +L+ +  R+G
Sbjct: 172 AGPPLTFSW-TGNALSPLD-PETTRS----------SELTLTPRPEDHGTNLTCQMKRQG 219

Query: 242 DSGKYYFQVERGSRKWNYIYDKLSVHV----TALTHMPTFSIPGTLESGHPRNLTCSVPW 297
                    ER + + N  Y   ++ +     AL  +   S    LE G    L C  P 
Sbjct: 220 AQ----VTTER-TVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLE-GQALRLLCDAP- 272

Query: 298 ACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357
                 P  ++W   S +     I+ + +L L           TC+   P   + +   +
Sbjct: 273 ---SNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQI--FL 327

Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSW---- 413
            L++   PQ L                 G + S  E + LH  C+  + P   L W    
Sbjct: 328 NLSVYSLPQLL-----------------GPSCS-WEAEGLHCRCSFRARPAPSLCWRLEE 369

Query: 414 -------TWGSLTLSPSQSSNLGVLELPRVH--VKDEGEFTCRAQNPLGSQHISLSLSLQ 464
                  + GS  ++ S +       L  +H  +  + + +C+A N  GSQ  S+ L   
Sbjct: 370 KPLEGNSSQGSFKVNSSSAGPWANSSL-ILHGGLSSDLKVSCKAWNIYGSQSGSVLL--- 425

Query: 465 NEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA--RPAVGVGDTGME 522
               G+    +GV   A GGAG  AL+ +  C+IF ++   R+K A  RP        M+
Sbjct: 426 --LQGRSNLGTGVVPAALGGAGVMALLCICLCLIFFLIVKARRKQAAGRP------EKMD 477

Query: 523 DANAVRGSASQGPLIESPADDSPPHHA-PPALATPSPEEGEIQYASLSFHKARPQYPQEQ 581
           D + + G+ + G   + P  DSP   A PP  A P  E+ E+ YASLSF + + + P++Q
Sbjct: 478 DEDPIMGTITSGSR-KKPWPDSPGDQASPPGDAPPLEEQKELHYASLSFSEMKSREPKDQ 536

Query: 582 EAIG-YEYSEINIPK 595
           EA    EYSEI   K
Sbjct: 537 EAPSTTEYSEIKTSK 551


>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
           sapiens]
          Length = 602

 Score =  288 bits (736), Expect = 1e-77
 Identities = 219/603 (36%), Positives = 304/603 (50%), Gaps = 48/603 (7%)

Query: 1   MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60
           MLLL LLLP L  G +   +   Y L +Q+ V V EGLCV V C+ SYP++GW  S   +
Sbjct: 13  MLLLPLLLPVLGAGSLN--KDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAY 70

Query: 61  GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120
           GYWF+         PVATNN +R V+  TRDRF L GDP    C+L IRD +  D   Y 
Sbjct: 71  GYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYF 130

Query: 121 FCVERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYN 179
           F VERG+ ++ ++  +   + VTA   L  +  + +PE  T++ G  V+V C      +N
Sbjct: 131 FRVERGSRVRHSFLSNAFFLKVTA---LTKKPDVYIPE--TLEPGQPVTVICV-----FN 180

Query: 180 WTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFL-LLGDPQTNNCSLS--IR 236
           W        S+   GA +         +P       +H   L     PQ ++  L+  + 
Sbjct: 181 WAFKKCPAPSFSWTGAAL---------SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVD 231

Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296
            +RKG S +   ++       + I   +S   T+   +    I   ++ G    L C   
Sbjct: 232 FSRKGVSAQRTVRLRVAYAPKDLIIS-ISHDNTSALELQGNVIYLEVQKGQFLRLLC--- 287

Query: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354
            A +   P T++W+     +SS  P   R+  L L           TC+        +  
Sbjct: 288 -AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQ 344

Query: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414
           +A+ L++ YPP+NL + V Q + T    L NG++L VLEGQSL LVC   S+PPARLSWT
Sbjct: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404

Query: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPI 474
               T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+      K+   
Sbjct: 405 RWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH----WKLEHG 460

Query: 475 SGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQG 534
            G+ LGA  GAG  AL+    C++   V+ CRK++ + A        +D  +  G  SQG
Sbjct: 461 GGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRA-----AAEQDVPSTLGPISQG 515

Query: 535 PLIESPADDSPPHHAPPALATPSP---EEGEIQYASLSFHKARPQYPQEQEAIG-YEYSE 590
              E  A  S   H PP  AT +P   EE E+ YASLSF   R   P +QEA    EYSE
Sbjct: 516 HQHECSAGSS-QDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSE 574

Query: 591 INI 593
           I I
Sbjct: 575 IKI 577


>gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens]
          Length = 364

 Score =  287 bits (735), Expect = 2e-77
 Identities = 140/251 (55%), Positives = 176/251 (70%)

Query: 153 LEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKV 212
           L+V ESVTVQEGLCV VPC+  +P   +  +SPV+G WF+EGA I  D PVATN    +V
Sbjct: 23  LQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEV 82

Query: 213 QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT 272
           QE+T GRF LLGDP  NNCSLSI DAR+ D+G Y+F++ERGS K++Y   +LSVHVT LT
Sbjct: 83  QEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLT 142

Query: 273 HMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQ 332
           H P   IPGTLE GH +NLTCSV WACEQGTPP  +W+ A+ +SL P  T SS+L + P+
Sbjct: 143 HRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPR 202

Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392
           PQDHGT+LTCQV   GAGVT  R ++LN++Y PQN T  +F GDG+     R G     +
Sbjct: 203 PQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAI 262

Query: 393 EGQSLHLVCAV 403
            G  +  + A+
Sbjct: 263 GGAGVTALLAL 273



 Score =  150 bits (380), Expect = 2e-36
 Identities = 86/189 (45%), Positives = 120/189 (63%), Gaps = 14/189 (7%)

Query: 4   LLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYW 63
           LLLLLP L  G +      ++ L +Q+SVTVQEGLCV V C+F +P   +  + PVHGYW
Sbjct: 3   LLLLLPLLWAGALAM--DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYW 60

Query: 64  FRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCV 123
           FR G  +SR+ PVATN   + VQEET+ RF LLGDP   +C+LSI D R  D G+Y F +
Sbjct: 61  FREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRM 120

Query: 124 ERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY-------P 176
           ERG+ K++YK  QLSV+VT   DL  R ++ +P   T++ G   ++ CSV +       P
Sbjct: 121 ERGSTKYSYKSPQLSVHVT---DLTHRPKILIPG--TLEPGHSKNLTCSVSWACEQGTPP 175

Query: 177 HYNWTASSP 185
            ++W +++P
Sbjct: 176 IFSWLSAAP 184



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 40/222 (18%)

Query: 394 GQSLHLVCAV----DSNPPARLSWTWGSLT-LSPSQSSNLGVLELPRVHVKDEG-EFTCR 447
           G S +L C+V    +   P   SW   + T L P  + +  ++  PR   +D G   TC+
Sbjct: 156 GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRP--QDHGTNLTCQ 213

Query: 448 AQNPLGSQHISLSLSLQNEY--------------TGKMRPISGVTLGAFGGAGATALVFL 493
            +          ++ L   Y              +GK    +GV  GA GGAG TAL+ L
Sbjct: 214 VKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLAL 273

Query: 494 YFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSAS----QGPLIESPADDSPPHHA 549
             C+IF +V++ R+K+AR AVG  DT     +   GSAS    +   +  P + S    A
Sbjct: 274 CLCLIFFIVKTHRRKAARTAVGRNDT-----HPTTGSASPKHQKKSKLHGPTETSSCSGA 328

Query: 550 PPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEI 591
            P +      + E+ YASL+FH   P      +    EYSE+
Sbjct: 329 APTVEM----DEELHYASLNFHGMNP-----SKDTSTEYSEV 361


>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
          Length = 697

 Score =  272 bits (696), Expect = 6e-73
 Identities = 153/336 (45%), Positives = 199/336 (59%), Gaps = 9/336 (2%)

Query: 137 LSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGAD 196
           LS  +  SQ +  R+ + V ESV V EGLC+SVPCS  YP  +WT S+P YG WFK   +
Sbjct: 7   LSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWFKAVTE 66

Query: 197 IPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR- 255
                PVATN  S +V+  T GRF L GDP   NCSL IRDA+  D  +Y+F+VERGS  
Sbjct: 67  TTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYV 126

Query: 256 KWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVS 315
           ++N++ D   + VTALT  P   IP TLE G P  + C   WA E+  PP+ +W GA++S
Sbjct: 127 RYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALS 186

Query: 316 S--LDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF 373
           S    PT +  S+LS  P+PQDH T LTC V     GV+  R VRL ++Y P++L +++ 
Sbjct: 187 SQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISIS 246

Query: 374 QGDGTASTTLRNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN---L 428
           + +  A      G+   L   +GQ L L+CA DS PPA LSW   +  LS S       L
Sbjct: 247 RDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL 306

Query: 429 GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
           G LELP V   D G +TCRA+N LGSQ  +L LS+Q
Sbjct: 307 G-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341



 Score =  254 bits (648), Expect = 2e-67
 Identities = 175/469 (37%), Positives = 247/469 (52%), Gaps = 38/469 (8%)

Query: 6   LLLPPLLCGRVGAKEQKD--YLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYW 63
           +LLP LL   +G  +  D  + + +Q+SV V EGLC+SV CSFSYP+  WT S P +GYW
Sbjct: 1   MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60

Query: 64  FRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCV 123
           F+A    ++  PVATN+ +R V+  TR RF L GDP   +C+L IRD +  D   Y F V
Sbjct: 61  FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120

Query: 124 ERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTA 182
           ERG+ +++N+  D   + VTA   L  +  + +PE  T++ G  V+V C      +NW  
Sbjct: 121 ERGSYVRYNFMNDGFFLKVTA---LTQKPDVYIPE--TLEPGQPVTVICV-----FNWAF 170

Query: 183 SSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLG---DPQTNNCSLS--IRD 237
                 S+   GA +           S +  + T   F +L     PQ +N  L+  +  
Sbjct: 171 EECPPPSFSWTGAAL-----------SSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDF 219

Query: 238 ARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGT-LESGHPRNLTCSVP 296
           +RKG S +   ++       + +      +  AL   P  ++P    + G    L C   
Sbjct: 220 SRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLC--- 276

Query: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354
            A +   P T++W+     +SS  P   R   L L           TC+        +  
Sbjct: 277 -AADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAE--NRLGSQQ 333

Query: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414
           RA+ L++ YPP+NL + V Q + T    L NG++L VLEGQSL LVC   S+PPARLSWT
Sbjct: 334 RALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWT 393

Query: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463
                LSPSQ S+ GVLELPRV V+ EGEFTC A++PLGSQH+SLSLS+
Sbjct: 394 QRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 58/225 (25%), Positives = 91/225 (40%), Gaps = 30/225 (13%)

Query: 393 EGQSLHLVCAVDSNPPARLSWTWG-----------SLTLSPSQSSNLGVLELPRVHVKDE 441
           E + LH  C+  ++P   L W  G           S  ++PS +       L        
Sbjct: 456 EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSS 515

Query: 442 G-EFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFV 500
           G    C A N  G+Q  S+ L L ++   K    +  + GAF G G TAL+FL   +I +
Sbjct: 516 GLRLRCEAWNVHGAQSGSI-LQLPDK---KGLISTAFSNGAFLGIGITALLFLCLALIIM 571

Query: 501 VV---RSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH--HAPPALAT 555
            +   R  + ++ RP      T ++  N V    + GPL +     + P+    P     
Sbjct: 572 KILPKRRTQTETPRPRFSRHSTILDYINVV---PTAGPLAQKRNQKATPNSPRTPLPPGA 628

Query: 556 PSPE-----EGEIQYASLSFHKARPQYPQEQEA-IGYEYSEINIP 594
           PSPE     + + Q  S    K+  Q P+ QE+     Y+ +N P
Sbjct: 629 PSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLNFP 673


>gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo
           sapiens]
          Length = 698

 Score =  239 bits (609), Expect = 7e-63
 Identities = 137/320 (42%), Positives = 180/320 (56%), Gaps = 7/320 (2%)

Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210
           Y L+V   V V EGLCV V C++ YP   W  S+  YG WFK         PVATN  S 
Sbjct: 34  YSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSR 93

Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHVT 269
           +V+  T  RF L GDP   +CSL IRDA++ D   Y+F+VERGSR + +++ +   + VT
Sbjct: 94  EVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVT 153

Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSS--LDPTITRSSML 327
           ALT  P   IP TLE G P  + C   WA ++   P+ +W GA++S     P+ +  S+L
Sbjct: 154 ALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVL 213

Query: 328 SLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGS 387
           S  P PQDH T LTC V     GV+  R VRL ++Y P++L +++   + +A     N  
Sbjct: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273

Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQS---SNLGVLELPRVHVKDEGEF 444
            L V +GQ L L+CA DS PPA LSW      LS S       LG LEL  V   D G +
Sbjct: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332

Query: 445 TCRAQNPLGSQHISLSLSLQ 464
           TCRA+N LGSQ  +L LS+Q
Sbjct: 333 TCRAENRLGSQQQALDLSVQ 352



 Score =  233 bits (595), Expect = 3e-61
 Identities = 169/469 (36%), Positives = 240/469 (51%), Gaps = 34/469 (7%)

Query: 1   MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60
           MLLL LLLP L  G +   +   Y L +Q+ V V EGLCV V C+ SYP++GW  S   +
Sbjct: 13  MLLLPLLLPVLGAGSLN--KDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAY 70

Query: 61  GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120
           GYWF+         PVATNN +R V+  TRDRF L GDP    C+L IRD +  D   Y 
Sbjct: 71  GYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYF 130

Query: 121 FCVERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYN 179
           F VERG+ ++ ++  +   + VTA   L  +  + +PE  T++ G  V+V C      +N
Sbjct: 131 FRVERGSRVRHSFLSNAFFLKVTA---LTKKPDVYIPE--TLEPGQPVTVICV-----FN 180

Query: 180 WTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFL-LLGDPQTNNCSLS--IR 236
           W        S+   GA +         +P       +H   L     PQ ++  L+  + 
Sbjct: 181 WAFKKCPAPSFSWTGAAL---------SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVD 231

Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296
            +RKG S +   ++       + I   +S   T+   +    I   ++ G    L C   
Sbjct: 232 FSRKGVSAQRTVRLRVAYAPKDLIIS-ISHDNTSALELQGNVIYLEVQKGQFLRLLC--- 287

Query: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354
            A +   P T++W+     +SS  P   R+  L L           TC+        +  
Sbjct: 288 -AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQ 344

Query: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414
           +A+ L++ YPP+NL + V Q + T    L NG++L VLEGQSL LVC   S+PPARLSWT
Sbjct: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404

Query: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463
               T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+
Sbjct: 405 RWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 113/392 (28%), Positives = 159/392 (40%), Gaps = 68/392 (17%)

Query: 233 LSIRDARKGDSGKYYFQVER--GSRKW------NYIYDKLSVHV-----TALTHMPTFSI 279
           L +R  R GDSG+Y  + E   GS++        Y  + L V V     T L ++   + 
Sbjct: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378

Query: 280 PGTLESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHG 337
              LE G    L C          P  ++W   G +V    P+     +L L P   +H 
Sbjct: 379 LPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPS--DPGVLELPPIQMEHE 431

Query: 338 TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397
              TC    P     ++  + L++ YPPQ L                 G + S  E + L
Sbjct: 432 GEFTCHAQHPLGSQHVS--LSLSVHYPPQLL-----------------GPSCS-WEAEGL 471

Query: 398 HLVCAVDSNPPARLSW-----------TWGSLTLSPSQSSNLGVLELPRVHVKDEG-EFT 445
           H  C+  ++P   L W           + GS  ++PS +       L        G    
Sbjct: 472 HCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLR 531

Query: 446 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSC 505
           C+A N  G+Q  S+   L     GK+    G+ LGA  GAG  AL+    C++   V+ C
Sbjct: 532 CKAWNVHGAQSGSVFQLLP----GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKIC 587

Query: 506 RKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSP---EEGE 562
           RK++ + A        +D  +  G  SQG   E  A  S   H PP  AT +P   EE E
Sbjct: 588 RKEARKRA-----AAEQDVPSTLGPISQGHQHECSAGSS-QDHPPPGAATYTPGKGEEQE 641

Query: 563 IQYASLSFHKARPQYPQEQEAIG-YEYSEINI 593
           + YASLSF   R   P +QEA    EYSEI I
Sbjct: 642 LHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673


>gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens]
          Length = 237

 Score =  149 bits (376), Expect = 7e-36
 Identities = 69/133 (51%), Positives = 88/133 (66%)

Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330
           LTH P   IPGTLE GH +NLTCSV WACEQGTPP  +W+ A+ +SL P  T SS+L + 
Sbjct: 14  LTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIIT 73

Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390
           P+PQDHGT+LTCQV   GAGVT  R ++LN++Y PQN T  +F GDG+     R G    
Sbjct: 74  PRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHG 133

Query: 391 VLEGQSLHLVCAV 403
            + G  +  + A+
Sbjct: 134 AIGGAGVTALLAL 146



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 40/222 (18%)

Query: 394 GQSLHLVCAV----DSNPPARLSWTWGSLT-LSPSQSSNLGVLELPRVHVKDEG-EFTCR 447
           G S +L C+V    +   P   SW   + T L P  + +  ++  PR   +D G   TC+
Sbjct: 29  GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRP--QDHGTNLTCQ 86

Query: 448 AQNPLGSQHISLSLSLQNEY--------------TGKMRPISGVTLGAFGGAGATALVFL 493
            +          ++ L   Y              +GK    +GV  GA GGAG TAL+ L
Sbjct: 87  VKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLAL 146

Query: 494 YFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSAS----QGPLIESPADDSPPHHA 549
             C+IF +V++ R+K+AR AVG  DT     +   GSAS    +   +  P + S    A
Sbjct: 147 CLCLIFFIVKTHRRKAARTAVGRNDT-----HPTTGSASPKHQKKSKLHGPTETSSCSGA 201

Query: 550 PPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEI 591
            P +      + E+ YASL+FH   P      +    EYSE+
Sbjct: 202 APTVEM----DEELHYASLNFHGMNP-----SKDTSTEYSEV 234


>gi|11225258 myelin associated glycoprotein isoform a precursor
           [Homo sapiens]
          Length = 626

 Score =  118 bits (296), Expect = 1e-26
 Identities = 95/385 (24%), Positives = 162/385 (42%), Gaps = 41/385 (10%)

Query: 155 VPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQE 214
           +P S++  EG CVS+PC   +P  +    + V+G W+          PV   + +  V E
Sbjct: 26  MPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHE 83

Query: 215 DTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM 274
              GR  LLGD    NC+L + +      GKYYF+ + G     Y + + S  V  + + 
Sbjct: 84  SFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYN-QYTFSEHS--VLDIVNT 140

Query: 275 PTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMG----------ASVSSLDPTITRS 324
           P   +P  + +G    ++C VP  C +   P ++W+G            +   + T  + 
Sbjct: 141 PNIVVPPEVVAGTEVEVSCMVPDNCPE-LRPELSWLGHEGLGEPAVLGRLREDEGTWVQV 199

Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384
           S+L  +P  + +G  L CQ + P   +       +++ YPP  + M              
Sbjct: 200 SLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEM-------------- 245

Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444
             S++  +EG  + L+C  DSNPP  L+W      L  + + +L +LEL  V   ++G +
Sbjct: 246 -NSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESL-LLELEEVTPAEDGVY 303

Query: 445 TCRAQNPLGSQHISLSLSL-----QNEYTGKMRPISGVTLGAF----GGAGATALVFLYF 495
            C A+N  G  + ++ LS+     +    G M  + G T+               +F   
Sbjct: 304 ACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEK 363

Query: 496 CIIFVVVRSCRKKSARPAVGVGDTG 520
            I+  V+     +   PAV   D G
Sbjct: 364 QILSTVIYESELQLELPAVSPEDDG 388



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 111/469 (23%), Positives = 180/469 (38%), Gaps = 66/469 (14%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           ++ L   PL    + A     +   M  S++  EG CVS+ C F +P     A   VHG 
Sbjct: 1   MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAV--VHGV 58

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           W+    +     PV   +  + V E  + R  LLGD   ++CTL + +      G Y F 
Sbjct: 59  WYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFR 118

Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVT----VQEGLCVSVPCSVLYPHY 178
            + G       Y+Q + +  +  D+++   + VP  V     V+    V   C  L P  
Sbjct: 119 GDLGG------YNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPEL 172

Query: 179 NWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED--THGRFLLLGDPQTNNCSLSIR 236
           +W            EG   P           G+++ED  T  +  LL    T   +   R
Sbjct: 173 SWLG---------HEGLGEP--------AVLGRLREDEGTWVQVSLLHFVPTREAN-GHR 214

Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296
              +        Q E G    +  Y  + V + +            +E  H  +L C   
Sbjct: 215 LGCQASFPNTTLQFE-GYASMDVKYPPVIVEMNSSVE--------AIEGSHV-SLLC--- 261

Query: 297 WACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTR 355
              +   PP +TWM    + L   +  S +L L    P + G          G      R
Sbjct: 262 -GADSNPPPLLTWM-RDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQD---NR 316

Query: 356 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW 415
            V L++ Y P   T+              NG+ ++V EG+++ ++C+  SNP   L+   
Sbjct: 317 TVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCSTQSNPDPILTIFK 361

Query: 416 GSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
               LS     +   LELP V  +D+GE+ C A+N  G +  + +LS++
Sbjct: 362 EKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVE 410


>gi|18104957 myelin associated glycoprotein isoform b precursor
           [Homo sapiens]
          Length = 582

 Score =  118 bits (296), Expect = 1e-26
 Identities = 95/385 (24%), Positives = 162/385 (42%), Gaps = 41/385 (10%)

Query: 155 VPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQE 214
           +P S++  EG CVS+PC   +P  +    + V+G W+          PV   + +  V E
Sbjct: 26  MPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHE 83

Query: 215 DTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM 274
              GR  LLGD    NC+L + +      GKYYF+ + G     Y + + S  V  + + 
Sbjct: 84  SFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYN-QYTFSEHS--VLDIVNT 140

Query: 275 PTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMG----------ASVSSLDPTITRS 324
           P   +P  + +G    ++C VP  C +   P ++W+G            +   + T  + 
Sbjct: 141 PNIVVPPEVVAGTEVEVSCMVPDNCPE-LRPELSWLGHEGLGEPAVLGRLREDEGTWVQV 199

Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384
           S+L  +P  + +G  L CQ + P   +       +++ YPP  + M              
Sbjct: 200 SLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEM-------------- 245

Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444
             S++  +EG  + L+C  DSNPP  L+W      L  + + +L +LEL  V   ++G +
Sbjct: 246 -NSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESL-LLELEEVTPAEDGVY 303

Query: 445 TCRAQNPLGSQHISLSLSL-----QNEYTGKMRPISGVTLGAF----GGAGATALVFLYF 495
            C A+N  G  + ++ LS+     +    G M  + G T+               +F   
Sbjct: 304 ACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEK 363

Query: 496 CIIFVVVRSCRKKSARPAVGVGDTG 520
            I+  V+     +   PAV   D G
Sbjct: 364 QILSTVIYESELQLELPAVSPEDDG 388



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 111/469 (23%), Positives = 180/469 (38%), Gaps = 66/469 (14%)

Query: 3   LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
           ++ L   PL    + A     +   M  S++  EG CVS+ C F +P     A   VHG 
Sbjct: 1   MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAV--VHGV 58

Query: 63  WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
           W+    +     PV   +  + V E  + R  LLGD   ++CTL + +      G Y F 
Sbjct: 59  WYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFR 118

Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVT----VQEGLCVSVPCSVLYPHY 178
            + G       Y+Q + +  +  D+++   + VP  V     V+    V   C  L P  
Sbjct: 119 GDLGG------YNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPEL 172

Query: 179 NWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED--THGRFLLLGDPQTNNCSLSIR 236
           +W            EG   P           G+++ED  T  +  LL    T   +   R
Sbjct: 173 SWLG---------HEGLGEP--------AVLGRLREDEGTWVQVSLLHFVPTREAN-GHR 214

Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296
              +        Q E G    +  Y  + V + +            +E  H  +L C   
Sbjct: 215 LGCQASFPNTTLQFE-GYASMDVKYPPVIVEMNSSVE--------AIEGSHV-SLLC--- 261

Query: 297 WACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTR 355
              +   PP +TWM    + L   +  S +L L    P + G          G      R
Sbjct: 262 -GADSNPPPLLTWM-RDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQD---NR 316

Query: 356 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW 415
            V L++ Y P   T+              NG+ ++V EG+++ ++C+  SNP   L+   
Sbjct: 317 TVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCSTQSNPDPILTIFK 361

Query: 416 GSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
               LS     +   LELP V  +D+GE+ C A+N  G +  + +LS++
Sbjct: 362 EKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVE 410


>gi|13489095 sialoadhesin precursor [Homo sapiens]
          Length = 1709

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 82/310 (26%), Positives = 135/310 (43%), Gaps = 33/310 (10%)

Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215
           P+ V   +G C+ +PC   +P  +      +   W+    D      V +++   K+ E 
Sbjct: 26  PQDVQGVKGSCLLIPCIFSFPA-DVEVPDGITAIWYY---DYSGQRQVVSHSADPKLVEA 81

Query: 216 T-HGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGS-RKWNYIYDKLSVHVTALTH 273
              GR   +G+P+   C+L ++D +  DSG Y F+ E     +W+ +   L V VT    
Sbjct: 82  RFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTL-VTVTEEPR 140

Query: 274 MPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGA--------SVSSLDPT-ITRS 324
           +PT + P  L  G   +  CS P+ C Q     + W G         +    +PT +   
Sbjct: 141 VPTIASPVELLEGTEVDFNCSTPYVCLQ-EQVRLQWQGQDPARSVTFNSQKFEPTGVGHL 199

Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384
             L +    QDHG  L CQ+++  A       + L + Y P+ + +            L 
Sbjct: 200 ETLHMAMSWQDHGRILRCQLSV--ANHRAQSEIHLQVKYAPKGVKI------------LL 245

Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444
           + S  ++L G+ + L C V+S+ PA  S  W  L       +  GVL LP+    D G +
Sbjct: 246 SPSGRNILPGELVTLTCQVNSSYPAVSSIKW--LKDGVRLQTKTGVLHLPQAAWSDAGVY 303

Query: 445 TCRAQNPLGS 454
           TC+A+N +GS
Sbjct: 304 TCQAENGVGS 313



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 71/245 (28%), Positives = 99/245 (40%), Gaps = 42/245 (17%)

Query: 229  NNCSLSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPG-TLES 285
            N   L I  A   D G Y  +     G    +  +D  +V+V           PG T+  
Sbjct: 1048 NTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQAVNVQVW--------PGATVRE 1099

Query: 286  GHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQ---DHGTSLTC 342
            G   NLTC V W        T TW       LD           IP P       TS  C
Sbjct: 1100 GQLVNLTCLV-WTTHPAQL-TYTWYQDGQQRLDA--------HSIPLPNVTVRDATSYRC 1149

Query: 343  QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402
             V  PG    ++R + L++ Y P+NL +T                 L    GQ   ++C 
Sbjct: 1150 GVGPPGRAPRLSRPITLDVLYAPRNLRLTYL---------------LESHGGQLALVLCT 1194

Query: 403  VDSNPPARLSWTWGSLTLSPSQSS---NLGVLELPRVHVKDEGEFTCRAQNPLGSQHISL 459
            VDS PPA+L+ +     L+ S ++   N   LEL     +DEG ++C A++PLG  + SL
Sbjct: 1195 VDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSL 1254

Query: 460  SLSLQ 464
             L L+
Sbjct: 1255 ELRLE 1259



 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 69/272 (25%), Positives = 98/272 (36%), Gaps = 49/272 (18%)

Query: 213  QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTA 270
            Q  +HGRF      + N+  L +R+   GDSG Y  +     GS   +  +      V  
Sbjct: 843  QVPSHGRFQ--AKAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQV 900

Query: 271  LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330
                   S    L+ G    L+C V     +GT       G  +        R + ++L 
Sbjct: 901  -------SPSPELQEGQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLT 953

Query: 331  PQPQDHGTSLTCQVTLPGAGVTMTRA-VRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389
                 H     CQ   PG+  T   A + L++SY P+++T+T     G     L      
Sbjct: 954  QAGAYH-----CQAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGL------ 1002

Query: 390  SVLEGQSLHLVCAVDSNPPARLSWTWGS-LTLSPSQSSNLGVLELPRVHV---------- 438
                     L+C VDS+PPA+L    G  L  S  Q         PR+HV          
Sbjct: 1003 ---------LLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLE 1053

Query: 439  ------KDEGEFTCRAQNPLGSQHISLSLSLQ 464
                  +DEG + C A N LG    S     Q
Sbjct: 1054 IHGAMLEDEGVYICEASNTLGQASASADFDAQ 1085



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 95/447 (21%), Positives = 168/447 (37%), Gaps = 77/447 (17%)

Query: 21  QKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNN 80
           Q  + ++  + V   +G C+ + C FS+P +     D +   W+   D+  +   V+ + 
Sbjct: 18  QASWGVSSPQDVQGVKGSCLLIPCIFSFPADV-EVPDGITAIWYY--DYSGQRQVVSHSA 74

Query: 81  PARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNM-KWNYKYDQLSV 139
             + V+   R R   +G+P+++ C L ++D +  D+G+Y F  E   + +W+   D    
Sbjct: 75  DPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWS---DVKGT 131

Query: 140 NVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------PHYNWTASSPVYGSWFKE 193
            VT +++        +   V + EG  V   CS  Y          W    P     F  
Sbjct: 132 LVTVTEEPRVP---TIASPVELLEGTEVDFNCSTPYVCLQEQVRLQWQGQDPARSVTFNS 188

Query: 194 GADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERG 253
               P  +            +D HGR L         C LS+ + R     + + QV+  
Sbjct: 189 QKFEPTGVGHLETLHMAMSWQD-HGRIL--------RCQLSVANHRA--QSEIHLQVKYA 237

Query: 254 SRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGAS 313
            +    +      ++          +PG L +     LTC V          +I W+   
Sbjct: 238 PKGVKILLSPSGRNI----------LPGELVT-----LTCQV--NSSYPAVSSIKWLKDG 280

Query: 314 VSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF 373
           V       T++ +L L           TCQ    G G         ++  PP  +++ +F
Sbjct: 281 VR----LQTKTGVLHLPQAAWSDAGVYTCQAE-NGVG---------SLVSPP--ISLHIF 324

Query: 374 QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW--GSLTLSPSQSSNLGVL 431
             +   S       A  +LE Q++ LVC   +  P+ L ++W    + L  + S  L   
Sbjct: 325 MAEVQVS------PAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTL--- 375

Query: 432 ELPRVHV---KDEGEFTCRAQNPLGSQ 455
              R+H+    D G + C  QN  GS+
Sbjct: 376 ---RLHLATRADTGFYFCEVQNVHGSE 399



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 48/200 (24%), Positives = 79/200 (39%), Gaps = 34/200 (17%)

Query: 282 TLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLT 341
           TL+ G   NLTC+V      G+P   +W    V      +     ++L+P  +       
Sbjct: 718 TLQEGTEANLTCNVSREAA-GSPANFSWFRNGVLWAQGPL---ETVTLLPVARTDAALYA 773

Query: 342 CQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVC 401
           C++ L  AG  ++  V L++ YPP    ++                 L + +G     +C
Sbjct: 774 CRI-LTEAGAQLSTPVLLSVLYPPDRPKLSAL---------------LDMGQGHMALFIC 817

Query: 402 AVDSNPPARLSWTWGSLTLSPS--------------QSSNLGVLELPRVHVKDEGEFTCR 447
            VDS P A L+   G   L+ S                +N   LE+  + + D G + C 
Sbjct: 818 TVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKLEVRELGLGDSGSYRCE 877

Query: 448 AQNPLGSQHISLSLSLQNEY 467
           A N LGS + SL   ++  +
Sbjct: 878 ATNVLGSSNTSLFFQVRGAW 897



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 34/133 (25%)

Query: 342  CQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVC 401
            C   LP  G   +  V L + YPP+  TM VF            G    +L+       C
Sbjct: 1511 CLAELP-TGAAASAPVMLRVLYPPKTPTMMVFVEP--------EGGLRGILD-------C 1554

Query: 402  AVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV----------------KDEGEFT 445
             VDS P A L+   GS  ++ SQ    G    P +HV                 D+GE+ 
Sbjct: 1555 RVDSEPLASLTLHLGSRLVASSQPQ--GAPAEPHIHVLASPNALRVDIEALRPSDQGEYI 1612

Query: 446  CRAQNPLGSQHIS 458
            C A N LGS   S
Sbjct: 1613 CSASNVLGSASTS 1625



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 54/239 (22%), Positives = 90/239 (37%), Gaps = 40/239 (16%)

Query: 229  NNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHP 288
            N   L +R  +  D G Y         + N   + L +    +   P  ++P     G P
Sbjct: 1222 NTLRLELRGPQPRDEGFYSCSARSPLGQANTSLE-LRLEGVRVILAPEAAVP----EGAP 1276

Query: 289  RNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPG 348
              +TC+ P A     P   TW        +     ++ LS +   + H  + +CQ     
Sbjct: 1277 ITVTCADPAA---HAPTLYTWYHNGRWLQEGP---AASLSFLVATRAHAGAYSCQAQ-DA 1329

Query: 349  AGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPP 408
             G   +R   L + Y PQ+  ++ F+     S  +               + C VDS PP
Sbjct: 1330 QGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAV---------------IQCTVDSEPP 1374

Query: 409  ARLSWTWGSLTLSPSQ-----SSNLGVLELP----RVHVKD----EGEFTCRAQNPLGS 454
            A L+ +     L+ S      +S  G +++     R+ V+D    +  + C AQN LGS
Sbjct: 1375 AELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDDTYVCTAQNLLGS 1433



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 63/266 (23%), Positives = 98/266 (36%), Gaps = 50/266 (18%)

Query: 224 GDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTL 283
           G    N+  L IRD  + DSG+Y       +         L  H  A   +   S    +
Sbjct: 467 GTSGPNSLRLEIRDLEETDSGEYKCSA---TNSLGNATSTLDFHANAARLL--ISPAAEV 521

Query: 284 ESGHPRNLTCSVPWACEQGTPPT----ITW-MGASVSSLDPTITRSSMLSLIPQPQDHGT 338
             G       +V  +C  G  PT     +W +  ++    P    SS+L       D G 
Sbjct: 522 VEGQ------AVTLSCRSGLSPTPDARFSWYLNGALLHEGPG---SSLLLPAASSTDAG- 571

Query: 339 SLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLH 398
           S  C+     +    +    L + YPP+  T T          T  +  A     G+   
Sbjct: 572 SYHCRARDGHSASGPSSPAVLTVLYPPRQPTFT----------TRLDLDAAGAGAGRRGL 621

Query: 399 LVCAVDSNPPARLSW------------------TWG--SLTLSPSQSSNLGVLELPRVHV 438
           L+C VDS+PPARL                    T G  S  +  +++ NL  +E+    +
Sbjct: 622 LLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLL 681

Query: 439 KDEGEFTCRAQNPLGSQHISLSLSLQ 464
           ++EG + C A N LG+   S + + Q
Sbjct: 682 EEEGLYLCEASNALGNASTSATFNGQ 707


>gi|157168355 CD22 molecule [Homo sapiens]
          Length = 847

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 76/317 (23%), Positives = 130/317 (41%), Gaps = 34/317 (10%)

Query: 149 SRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTP 208
           S++  E PE++   EG CV +PC+      +  +    +   + +         +  +T 
Sbjct: 22  SKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFHNPEYNKNTSKFDGTRLYESTK 81

Query: 209 SGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHV 268
            GKV  +   R   LGD +  NC+LSI      DSG+   ++E  + KW    +++ ++V
Sbjct: 82  DGKVPSEQK-RVQFLGD-KNKNCTLSIHPVHLNDSGQLGLRMESKTEKW---MERIHLNV 136

Query: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSM-- 326
           +     P   +P  ++      LTC + ++C  G P  + W+   V      +T +S+  
Sbjct: 137 SERPFPPHIQLPPEIQESQEVTLTCLLNFSC-YGYPIQLQWLLEGVPMRQAAVTSTSLTI 195

Query: 327 --------LSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGT 378
                   L   PQ   HG  +TCQ+            V+LN+ + P+ L + V   D  
Sbjct: 196 KSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKHTPK-LEIKVTPSDAI 254

Query: 379 ASTTLRNGSALSVLEGQSLHLVCAVDSNPP--ARLSWTWGSLTLSPSQSSNLGVLELPRV 436
                       V EG S+ + C V S+ P    +SW     +L   +  N   L L  V
Sbjct: 255 ------------VREGDSVTMTCEVSSSNPEYTTVSWLKDGTSL---KKQNTFTLNLREV 299

Query: 437 HVKDEGEFTCRAQNPLG 453
                G++ C+  N +G
Sbjct: 300 TKDQSGKYCCQVSNDVG 316



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 84/383 (21%), Positives = 150/383 (39%), Gaps = 57/383 (14%)

Query: 92  RFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRY 151
           R   LGD +NK+CTLSI     +D+G     +E    KW    +++ +NV+        +
Sbjct: 91  RVQFLGD-KNKNCTLSIHPVHLNDSGQLGLRMESKTEKW---MERIHLNVSERP-----F 141

Query: 152 RLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGK 211
              +     +QE   V++ C + +  Y +    P+   W  EG  +P      T+T    
Sbjct: 142 PPHIQLPPEIQESQEVTLTCLLNFSCYGY----PIQLQWLLEG--VPMRQAAVTST--SL 193

Query: 212 VQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY-DKLSVHVTA 270
             +    R  L   PQ ++    +    +   GK+   +   + + N  +  KL + VT 
Sbjct: 194 TIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKF---LSNDTVQLNVKHTPKLEIKVT- 249

Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLS 328
               P+ +I   +  G    +TC V  +  + T  T++W+  G S+   + T T    L+
Sbjct: 250 ----PSDAI---VREGDSVTMTCEVSSSNPEYT--TVSWLKDGTSLKKQN-TFT----LN 295

Query: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388
           L    +D      CQV+    G   +  V L + Y P+  T+ +                
Sbjct: 296 LREVTKDQSGKYCCQVS-NDVGPGRSEEVFLQVQYAPEPSTVQILHS------------- 341

Query: 389 LSVLEGQSLHLVCAVDSNP-PARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCR 447
              +EG  +  +C   +NP P   +W      +   Q      + +P++     G ++C 
Sbjct: 342 -PAVEGSQVEFLCMSLANPLPTNYTWYHNGKEM---QGRTEEKVHIPKILPWHAGTYSCV 397

Query: 448 AQNPLGSQHISLSLSLQNEYTGK 470
           A+N LG+        L  +Y  K
Sbjct: 398 AENILGTGQRGPGAELDVQYPPK 420



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 21/130 (16%)

Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392
           P+D G S +C V     G T ++A  L + Y P+ L +++  GD              V+
Sbjct: 563 PEDAG-SYSCWVN-NSIGQTASKAWTLEVLYAPRRLRVSMSPGD-------------QVM 607

Query: 393 EGQSLHLVCAVDSNPP-ARLSW-TWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450
           EG+S  L C  D+NPP +  +W  W + +L P  S     L L  V V+  G + C+  N
Sbjct: 608 EGKSATLTCESDANPPVSHYTWFDWNNQSL-PYHSQK---LRLEPVKVQHSGAYWCQGTN 663

Query: 451 PLGSQHISLS 460
            +G     LS
Sbjct: 664 SVGKGRSPLS 673


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 80/360 (22%), Positives = 130/360 (36%), Gaps = 46/360 (12%)

Query: 106  LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165
            L I   + SDAGTYV C+ +  +    K  ++ V+  A      + + E  E +TV+ G 
Sbjct: 3170 LQISSAKPSDAGTYV-CLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGH 3227

Query: 166  CVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGD 225
              ++ CS        T S      W K  + +PW           +++ DT         
Sbjct: 3228 TATLRCSA-------TGSPAPTIHWSKLRSPLPWQ---------HRLEGDT--------- 3262

Query: 226  PQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLES 285
                   L I    + DSG+Y   +   +    +    + +HV +  +  T     ++++
Sbjct: 3263 -------LIIPRVAQQDSGQY---ICNATSPAGHAEATIILHVESPPYATTVPEHASVQA 3312

Query: 286  GHPRNLTCSVPWACEQGTPP-TITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQV 344
            G    L C        GTPP T  W     S       R+ +L       +      C+V
Sbjct: 3313 GETVQLQCLA-----HGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRV 3367

Query: 345  TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404
            T            +L +  PP +L  T      T +  +        + G S+   CAV 
Sbjct: 3368 TNKVGSAEAF--AQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSI-GASVEFHCAVP 3424

Query: 405  SNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            S+   +L W      L P  S   GVL +  +    +G + C+A  P G    S  L +Q
Sbjct: 3425 SDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQ 3484



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 75/259 (28%), Positives = 110/259 (42%), Gaps = 49/259 (18%)

Query: 227  QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTAL-----THMPTFSIPG 281
            Q +   L +      DSG+Y  +V   S        + SV VT       +H    + P 
Sbjct: 2482 QVHGSRLRLLQVTPADSGEYVCRVVGSSGT-----QEASVLVTIQQRLSGSHSQGVAYPV 2536

Query: 282  TLES-------GHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQ 332
             +ES       GH  +L C V        P TITW   G S+ S    +   S L  IPQ
Sbjct: 2537 RIESSSASLANGHTLDLNCLVA----SQAPHTITWYKRGGSLPSRHQIV--GSRLR-IPQ 2589

Query: 333  --PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTA-----STTLR- 384
              P D G    C V+  GAG   T            +L +T+ QG G++     S  +R 
Sbjct: 2590 VTPADSG-EYVCHVS-NGAGSRET------------SLIVTI-QGSGSSHVPSVSPPIRI 2634

Query: 385  NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444
              S+ +V+EGQ+L L C V   P A ++W     +L     ++   L L ++ V D GE+
Sbjct: 2635 ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEY 2694

Query: 445  TCRAQNPLGSQHISLSLSL 463
             CRA N + +   S+ +S+
Sbjct: 2695 VCRANNNIDALEASIVISV 2713



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 94/383 (24%), Positives = 141/383 (36%), Gaps = 66/383 (17%)

Query: 106  LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165
            L+IR+ + SDAGTYV C   G+  +       +++V AS  L +      P  +TVQ G 
Sbjct: 1825 LTIRNVQLSDAGTYV-CT--GSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1881

Query: 166  CVSVPCSVL---YPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLL 222
                 CS      P   WT            G  +P              +   HG  L 
Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGP---------GGQLP-------------AKAQIHGGILR 1919

Query: 223  LGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGT 282
            L   +  + +  +  A    +G+   QV R           L VH      +        
Sbjct: 1920 LPAVEPTDQAQYLCRAHSS-AGQ---QVARAV---------LHVHGGGGPRVQVSPERTQ 1966

Query: 283  LESGHPRNLTCSVPWACEQGTPP-TITWMGASVSSLDPTITRSSMLSLIPQPQ----DHG 337
            + +G    L C        G P  TITW             R    SL PQ +    D  
Sbjct: 1967 VHAGRTVRLYCRAA-----GVPSATITW-------------RKEGGSLPPQARSERTDIA 2008

Query: 338  TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397
            T L   +T   AG  +  A     +   +   + +   D +        S+ SV EGQ+L
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068

Query: 398  HLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHI 457
             L C V  +  A+++W     +L P    +   L LP+V   D GE+ CR +N  G +  
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEA 2128

Query: 458  SLSLS-LQNEYTG-KMRPISGVT 478
            S+++S L   ++G    P+ G T
Sbjct: 2129 SITVSVLHGTHSGPSYTPVPGST 2151



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 91/394 (23%), Positives = 150/394 (38%), Gaps = 69/394 (17%)

Query: 106  LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165
            L +     +D+G YV  V   +        + SV VT  Q L   +   V   V ++   
Sbjct: 2488 LRLLQVTPADSGEYVCRVVGSSGT-----QEASVLVTIQQRLSGSHSQGVAYPVRIESSS 2542

Query: 166  CVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGD 225
                    L  +    + +P   +W+K G  +P                    R  ++G 
Sbjct: 2543 ASLANGHTLDLNCLVASQAPHTITWYKRGGSLP-------------------SRHQIVGS 2583

Query: 226  PQTNNCSLSIRDARKGDSGKYYFQVERG--SRKWNYIYDKLSVHVTALTHMPTFSIPGTL 283
                   L I      DSG+Y   V  G  SR+ + I   +++  +  +H+P+ S P  +
Sbjct: 2584 ------RLRIPQVTPADSGEYVCHVSNGAGSRETSLI---VTIQGSGSSHVPSVSPPIRI 2634

Query: 284  ESGHP---RNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGT 338
            ES  P      T  +     +     ITW   G S+ S               + Q HG+
Sbjct: 2635 ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS---------------RHQTHGS 2679

Query: 339  SLTC-QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGT-----ASTTLRNGSALS-V 391
             L   Q+++  +G  + RA   NI     ++ ++V    G+     +S  +R  S+ S V
Sbjct: 2680 HLRLHQMSVADSGEYVCRANN-NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHV 2738

Query: 392  LEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNP 451
             EG++L L C V     A+++W     +L     +    L L  V   D GE+ CR    
Sbjct: 2739 AEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGS 2798

Query: 452  LGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGA 485
             G    S+ +++  E +G     S V + A GGA
Sbjct: 2799 SGPLEASVLVTI--EASGS----SAVHVPAPGGA 2826



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 64/325 (19%)

Query: 158  SVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTH 217
            S TV EG  + + C V          +    +W+K G  +P                   
Sbjct: 2253 SSTVAEGQTLDLSCVV-------AGQAHAQVTWYKRGGSLP------------------- 2286

Query: 218  GRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA-----LT 272
                     Q     L I  A   D+G+Y  +   G          ++V VT      L 
Sbjct: 2287 ------ARHQVRGSRLYIFQASPADAGQYVCRASNGMEA------SITVTVTGTQGANLA 2334

Query: 273  HMPTFSIPGTLE-------SGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSS 325
            +    + P  +E        G   +L C VP          +TW     S      T  S
Sbjct: 2335 YPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHA----QVTWHKRGGSLPVRHQTHGS 2390

Query: 326  MLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384
            +L L    P D G    C+V   G+ V +  +V + I   P      +    G   T   
Sbjct: 2391 LLRLYQASPADSG-EYVCRVL--GSSVPLEASVLVTIE--PAGSVPAL----GVTPTVRI 2441

Query: 385  NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444
              S+  V EGQ+L L C V     A+++W     +L      +   L L +V   D GE+
Sbjct: 2442 ESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEY 2501

Query: 445  TCRAQNPLGSQHISLSLSLQNEYTG 469
             CR     G+Q  S+ +++Q   +G
Sbjct: 2502 VCRVVGSSGTQEASVLVTIQQRLSG 2526



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 60/254 (23%), Positives = 97/254 (38%), Gaps = 23/254 (9%)

Query: 227  QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTF---SIPGTL 283
            QT+   L +      DSG+Y   V R +   + +   + + V+     P+    S+P  +
Sbjct: 2675 QTHGSHLRLHQMSVADSGEY---VCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRI 2731

Query: 284  ES-------GHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP-QPQD 335
            ES       G   +L C VP          +TW     S      TR S L L    P D
Sbjct: 2732 ESSSSHVAEGETLDLNCVVPGQAHA----QVTWHKRGGSLPSHHQTRGSRLRLHHVSPAD 2787

Query: 336  HGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQ 395
             G    C+V   G+   +  +V + I     +         G A       S+  V EGQ
Sbjct: 2788 SG-EYVCRVM--GSSGPLEASVLVTIEASGSSAVHV--PAPGGAPPIRIEPSSSRVAEGQ 2842

Query: 396  SLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455
            +L L C V     A+++W      L      +  +L L +V   D GE++C+     G+ 
Sbjct: 2843 TLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902

Query: 456  HISLSLSLQNEYTG 469
              S+ ++++    G
Sbjct: 2903 EASVLVTIEPSSPG 2916



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 59/241 (24%), Positives = 90/241 (37%), Gaps = 24/241 (9%)

Query: 227  QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY-------DKLSVHVTALTHMPTFSI 279
            QT    L +      DSG+Y  +V   S                 +VHV A    P   I
Sbjct: 2772 QTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRI 2831

Query: 280  PGT---LESGHPRNLTCSVPWACEQGTPPTITW--MGASVSSLDPTITRSSMLSLIPQPQ 334
              +   +  G   +L C VP          +TW   G ++ +          L+ +  P 
Sbjct: 2832 EPSSSRVAEGQTLDLKCVVPGQAHA----QVTWHKRGGNLPARHQVHGPLLRLNQV-SPA 2886

Query: 335  DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394
            D G   +CQVT  G+  T+  +V + I    +  +       G A       S+  V EG
Sbjct: 2887 DSG-EYSCQVT--GSSGTLEASVLVTI----EPSSPGPIPAPGLAQPIYIEASSSHVTEG 2939

Query: 395  QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
            Q+L L C V     A+++W     +L     ++   L L  V   D GE+ CRA +  G 
Sbjct: 2940 QTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGP 2999

Query: 455  Q 455
            +
Sbjct: 3000 E 3000



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 85/360 (23%), Positives = 132/360 (36%), Gaps = 68/360 (18%)

Query: 106  LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165
            L     + SDAG Y+ C  R   + N    +L V    S+ +     +E   S +V+ G 
Sbjct: 1731 LHFPSVQPSDAGVYI-CTCRNLHQSNTSRAELLVTEAPSKPIT--VTVEEQRSQSVRPGA 1787

Query: 166  CVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGD 225
             V+  C+         + SP Y         + W     T   +GK+             
Sbjct: 1788 DVTFICTA-------KSKSPAY--------TLVW-----TRLHNGKLPTRA--------- 1818

Query: 226  PQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLES 285
                N  L+IR+ +  D+G Y   V  GS  +       ++HV A     T S P  + S
Sbjct: 1819 -MDFNGILTIRNVQLSDAGTY---VCTGSNMFAMDQGTATLHVQA---SGTLSAP--VVS 1869

Query: 286  GHPRNLTCSVPWACE-----QGTP-PTITWMGASVSSLDPTITRSSMLSLIP--QPQDHG 337
             HP  LT       E      G+P PT+ W G     L         +  +P  +P D  
Sbjct: 1870 IHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQA 1929

Query: 338  TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397
              L C+     AG  + RAV            + V  G G       +     V  G+++
Sbjct: 1930 QYL-CRAH-SSAGQQVARAV------------LHVHGGGGPRVQV--SPERTQVHAGRTV 1973

Query: 398  HLVCAVDSNPPARLSWTWGSLTLSP---SQSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
             L C     P A ++W     +L P   S+ +++  L +P +   D G + C A +P G+
Sbjct: 1974 RLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT 2033



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 87/390 (22%), Positives = 132/390 (33%), Gaps = 72/390 (18%)

Query: 106  LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRY----------RLEV 155
            L +     +D+G YV  VE G+     K   ++V+V         Y          R+E 
Sbjct: 2102 LRLPQVSPADSGEYVCRVENGS---GPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIE- 2157

Query: 156  PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215
            P S  V EG  + + C V          +    +W K G  +P              +  
Sbjct: 2158 PSSSHVAEGQTLDLNCVV-------PGQAHAQVTWHKRGGSLP-------------ARHQ 2197

Query: 216  THGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWN---YIYDKLSVHVTALT 272
            THG  L L                  DSG+Y   V   S        +  + SV    + 
Sbjct: 2198 THGSLLRL------------HQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIP 2245

Query: 273  HMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQ 332
             +   S   T+  G   +L+C V           +TW     S       R S L +   
Sbjct: 2246 PVRIESSSSTVAEGQTLDLSCVVAGQAHA----QVTWYKRGGSLPARHQVRGSRLYIFQA 2301

Query: 333  PQDHGTSLTCQVTL---PGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389
                     C+ +        VT+T     N++YP            G+        S+ 
Sbjct: 2302 SPADAGQYVCRASNGMEASITVTVTGTQGANLAYPA-----------GSTQPIRIEPSSS 2350

Query: 390  SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449
             V EGQ+L L C V     A+++W     +L     ++  +L L +    D GE+ CR  
Sbjct: 2351 QVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRV- 2409

Query: 450  NPLGSQ-HISLSLSLQNEYTGKMRPISGVT 478
              LGS   +  S+ +  E  G + P  GVT
Sbjct: 2410 --LGSSVPLEASVLVTIEPAGSV-PALGVT 2436



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 87/361 (24%), Positives = 131/361 (36%), Gaps = 69/361 (19%)

Query: 105  TLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEG 164
            TL I     +DAG Y+ CV            Q+ V ++AS       ++E   S +V EG
Sbjct: 2009 TLLIPAITTADAGFYL-CVATSPAGTAQARIQVVV-LSASDASPPPVKIE-SSSPSVTEG 2065

Query: 165  LCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLG 224
              + + C V         S+    +W++ G  +P         P  +V    HG  L L 
Sbjct: 2066 QTLDLNCVV-------AGSAHAQVTWYRRGGSLP---------PHTQV----HGSRLRL- 2104

Query: 225  DPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM-PTFS-IPGT 282
             PQ +            DSG+Y  +VE GS         ++V V   TH  P+++ +PG+
Sbjct: 2105 -PQVS----------PADSGEYVCRVENGSGPKE---ASITVSVLHGTHSGPSYTPVPGS 2150

Query: 283  ------------LESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330
                        +  G   +L C VP          +TW     S      T  S+L L 
Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAH----AQVTWHKRGGSLPARHQTHGSLLRLH 2206

Query: 331  P-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389
               P D G    C V      +  +  V +  S  P           G         S+ 
Sbjct: 2207 QVTPADSG-EYVCHVVGTSGPLEASVLVTIEASVIP-----------GPIPPVRIESSSS 2254

Query: 390  SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449
            +V EGQ+L L C V     A+++W     +L          L + +    D G++ CRA 
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2314

Query: 450  N 450
            N
Sbjct: 2315 N 2315



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 14/149 (9%)

Query: 328  SLIPQPQDHGTSLTC-QVTLPGAGVTMTRAVRLNISYPPQ-NLTMTVFQGD--------- 376
            SL P  Q HG+ L   QV+   +G  + R    N S P + ++T++V  G          
Sbjct: 2090 SLPPHTQVHGSRLRLPQVSPADSGEYVCRVE--NGSGPKEASITVSVLHGTHSGPSYTPV 2147

Query: 377  -GTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPR 435
             G+        S+  V EGQ+L L C V     A+++W     +L     ++  +L L +
Sbjct: 2148 PGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQ 2207

Query: 436  VHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            V   D GE+ C      G    S+ ++++
Sbjct: 2208 VTPADSGEYVCHVVGTSGPLEASVLVTIE 2236



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 48/206 (23%), Positives = 74/206 (35%), Gaps = 21/206 (10%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRA 448
            L+V  G +  L C+   +P   + W+     L          L +PRV  +D G++ C A
Sbjct: 3221 LTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNA 3280

Query: 449  QNPLGSQHISLSLSLQN-EYTGKMRPISGVTLGAFG-----GAGATALVFLYFCI----- 497
             +P G    ++ L +++  Y   +   + V  G          G   L F +  +     
Sbjct: 3281 TSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLP 3340

Query: 498  --------IFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHA 549
                    +    R+  + S R    V +  +  A A      QGP    PA   P    
Sbjct: 3341 GRATARNELLHFERAAPEDSGRYRCRVTNK-VGSAEAFAQLLVQGPPGSLPATSIPAGST 3399

Query: 550  PPALATPSPEEGEIQYASLSFHKARP 575
            P    TP  E   I  AS+ FH A P
Sbjct: 3400 PTVQVTPQLETKSIG-ASVEFHCAVP 3424



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 57/264 (21%), Positives = 98/264 (37%), Gaps = 41/264 (15%)

Query: 227  QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT----HMPTFSIP-- 280
            QT+   L +      DSG+Y  +   G          ++V  +  +      P  SI   
Sbjct: 2970 QTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPP 3029

Query: 281  -GTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP----QPQD 335
              T++ G   +  C +    +   P ++ W   +   L+  +  S   S+I     +P +
Sbjct: 3030 SSTVQQGQDASFKCLIH---DGAAPISLEWKTRN-QELEDNVHISPNGSIITIVGTRPSN 3085

Query: 336  HGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQ 395
            HGT   C V     GV  +  V L++  PP              + ++     + V  G+
Sbjct: 3086 HGT-YRC-VASNAYGVAQS-VVNLSVHGPP--------------TVSVLPEGPVWVKVGK 3128

Query: 396  SLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG------VLELPRVHVKDEGEFTCRAQ 449
            ++ L C     P +   WT  S T +  +    G      VL++      D G + C AQ
Sbjct: 3129 AVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQ 3188

Query: 450  NPLGSQHISLSLSLQNEYTGKMRP 473
            N LG+    + + +    TG M P
Sbjct: 3189 NALGTAQKQVEVIVD---TGAMAP 3209



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 6/72 (8%)

Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSW--TWGSLTLSP----SQSSNLGVLELPRVHVKDE 441
           ++    GQ++   C     P   ++W   WG +   P    +     G L +  V   D+
Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 474

Query: 442 GEFTCRAQNPLG 453
           G +TC A N  G
Sbjct: 475 GAYTCEAMNARG 486



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 380  STTLRNGSALSVLEGQSLHLVCAVDSNPPA-RLSWTWGSLTLSPSQSSNL-GVLELPRVH 437
            + T+    + SV  G  +  +C   S  PA  L WT       P+++ +  G+L +  V 
Sbjct: 1772 TVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQ 1831

Query: 438  VKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            + D G + C   N       + +L +Q
Sbjct: 1832 LSDAGTYVCTGSNMFAMDQGTATLHVQ 1858



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 17/60 (28%), Positives = 24/60 (40%)

Query: 394  GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLG 453
            G +    C     P   +SW+    +L P       +L LP V  +D G + C A N  G
Sbjct: 3589 GSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQG 3648


>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
          Length = 1349

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 88/354 (24%), Positives = 142/354 (40%), Gaps = 63/354 (17%)

Query: 154 EVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYG-SWFKEGADIPWDIPVATNTPSGKV 212
           E PE VT + G  V + C V++P    T   P Y   WFK G  IP  I      P   V
Sbjct: 28  EEPEFVTARAGESVVLRCDVIHPV---TGQPPPYVVEWFKFGVPIPIFIKFGYYPPH--V 82

Query: 213 QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT 272
             +  GR  L      +  SL +   R  D G Y  +V    ++++  ++   VH+T + 
Sbjct: 83  DPEYAGRASL-----HDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLT-IN 136

Query: 273 HMPTFSI--PGTLES--GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSS 325
             PTF+   P  +E+  G    +TC+       G P P +TW+  G  + +         
Sbjct: 137 APPTFTETPPQYIEAKEGGSITMTCTA-----FGNPKPIVTWLKEGTLLGASGKYQVSDG 191

Query: 326 MLSLIPQPQDHGTSLTCQV-TLPGAGVTMTRAVRLN---ISYPPQNLTMTVFQGDGTAST 381
            L++    ++   + TC+  ++ G  V  T  +      I  PP+N+T+ +         
Sbjct: 192 SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNI--------- 242

Query: 382 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---------GVLE 432
                        Q   L C  ++ P   L++TW     +    ++L         G L 
Sbjct: 243 ------------SQDALLTCRAEAYP-GNLTYTWYWQDENVYFQNDLKLRVRILIDGTLI 289

Query: 433 LPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK---MRPISGVTLGAFG 483
           + RV  +D G++TC   N LG +  S S  L  +Y  +   M P+  V +G  G
Sbjct: 290 IFRVKPEDSGKYTCVPSNSLG-RSPSASAYLTVQYPARVLNMPPVIYVPVGIHG 342


>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
          Length = 1863

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 84/332 (25%), Positives = 117/332 (35%), Gaps = 51/332 (15%)

Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215
           P+S  V+E   V   C V       +       +WF EG       PV     S +V ED
Sbjct: 420 PQSQEVKENQTVKFRCEV-------SGIPKPEVAWFLEGT------PVRRQEGSIEVYED 466

Query: 216 THGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERG----SRKWNYIYDKLSVHVTAL 271
               +L L              AR  DSG Y           S  W    ++L+V   A 
Sbjct: 467 AGSHYLCL------------LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514

Query: 272 THMPTFSIPGTLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLS 328
           +          +E G    L CSV     +GTP P ITW+  G  +     T   + +  
Sbjct: 515 SFSSVLKDCAVIE-GQDFVLQCSV-----RGTPVPRITWLLNGQPIQYARSTC-EAGVAE 567

Query: 329 LIPQ---PQDHGTSLTC--QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTL 383
           L  Q   P+DHGT  TC  +  L     +    V    S       + V     TA   L
Sbjct: 568 LHIQDALPEDHGT-YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626

Query: 384 RNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVH 437
           +  S L V++G  + +   V  NPP  + W      +  S      Q      L +  V 
Sbjct: 627 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686

Query: 438 VKDEGEFTCRAQNPLGSQHISLSLSLQNEYTG 469
            +D G +TC A N  G       L++Q  + G
Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 44/197 (22%)

Query: 374  QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSP------SQSSN 427
            +  GTA    +    + V EG+ L L C V S+PPA + WT    TL        SQ  +
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151

Query: 428  LGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGA 487
            L  + + +   +D G + C A+N  G    S  +++ +       P S  T         
Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD------APASENTKAP------ 1199

Query: 488  TALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH 547
                          ++S R KS+ P              V G+ S   + + PA  +PP 
Sbjct: 1200 -------------EMKSRRPKSSLP-------------PVLGTESDATVKKKPAPKTPPK 1233

Query: 548  HAPPALATPSPEEGEIQ 564
             A P      PE+ +++
Sbjct: 1234 AAMPPQIIQFPEDQKVR 1250



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVHVKDEGEF 444
           V EGQ     C +   P  +++W  G++ L PS      + + + VLE+  V+  D G +
Sbjct: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231

Query: 445 TCRAQNPLGSQHISLSLSLQ 464
           TC   N  G   +S  LS+Q
Sbjct: 232 TCLVVNGSGKASMSAELSIQ 251



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 12/119 (10%)

Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417
           +L+ S+  Q   + V +   + S+ L++    +V+EGQ   L C+V   P  R++W    
Sbjct: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKD---CAVIEGQDFVLQCSVRGTPVPRITWLLNG 551

Query: 418 LTLSPSQSS-NLGVLELPRVHV-----KDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470
             +  ++S+   GV EL   H+     +D G +TC A+N LG    S  +++  + + +
Sbjct: 552 QPIQYARSTCEAGVAEL---HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 8/100 (8%)

Query: 389 LSVLEGQSLHLVCAVDSNPPARLSW-------TWGSLTLSPSQSSNLGVLELPRVHVKDE 441
           L + EG +      V   P  +++W       T G   L          L +  VH +D 
Sbjct: 42  LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101

Query: 442 GEFTCRAQNPLGSQHISLSLSLQNEYTGKM-RPISGVTLG 480
           G++TC A N  G++ +++ L+++  +  ++ +P+   TLG
Sbjct: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 20/140 (14%)

Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392
           P+D GT  TC+     AG   T+AV L +  P           DGT    +    +++  
Sbjct: 687 PEDTGT-YTCEAW-NSAGEVRTQAV-LTVQEPH----------DGTQPWFISKPRSVTAS 733

Query: 393 EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS-------QSSNLGVLELPRVHVKDEGEFT 445
            GQS+ + CA+  +P   + W      L          Q+ ++  L L +V     G++ 
Sbjct: 734 LGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYE 793

Query: 446 CRAQNPLGSQHISLSLSLQN 465
              +N +G     +SL LQN
Sbjct: 794 ILLKNRVGECSCQVSLMLQN 813



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 10/98 (10%)

Query: 380  STTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGV-------LE 432
            S T+R+   L V+EG +    C ++  P   + W     ++  S+   +         L 
Sbjct: 1761 SKTIRD---LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817

Query: 433  LPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470
            +  V   D+ ++TC+A N LG    +  L ++    G+
Sbjct: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855


>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
          Length = 1914

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 84/332 (25%), Positives = 117/332 (35%), Gaps = 51/332 (15%)

Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215
           P+S  V+E   V   C V       +       +WF EG       PV     S +V ED
Sbjct: 420 PQSQEVKENQTVKFRCEV-------SGIPKPEVAWFLEGT------PVRRQEGSIEVYED 466

Query: 216 THGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERG----SRKWNYIYDKLSVHVTAL 271
               +L L              AR  DSG Y           S  W    ++L+V   A 
Sbjct: 467 AGSHYLCL------------LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514

Query: 272 THMPTFSIPGTLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLS 328
           +          +E G    L CSV     +GTP P ITW+  G  +     T   + +  
Sbjct: 515 SFSSVLKDCAVIE-GQDFVLQCSV-----RGTPVPRITWLLNGQPIQYARSTC-EAGVAE 567

Query: 329 LIPQ---PQDHGTSLTC--QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTL 383
           L  Q   P+DHGT  TC  +  L     +    V    S       + V     TA   L
Sbjct: 568 LHIQDALPEDHGT-YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626

Query: 384 RNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVH 437
           +  S L V++G  + +   V  NPP  + W      +  S      Q      L +  V 
Sbjct: 627 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686

Query: 438 VKDEGEFTCRAQNPLGSQHISLSLSLQNEYTG 469
            +D G +TC A N  G       L++Q  + G
Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 44/197 (22%)

Query: 374  QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSP------SQSSN 427
            +  GTA    +    + V EG+ L L C V S+PPA + WT    TL        SQ  +
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151

Query: 428  LGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGA 487
            L  + + +   +D G + C A+N  G    S  +++ +       P S  T         
Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD------APASENTKAP------ 1199

Query: 488  TALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH 547
                          ++S R KS+ P              V G+ S   + + PA  +PP 
Sbjct: 1200 -------------EMKSRRPKSSLP-------------PVLGTESDATVKKKPAPKTPPK 1233

Query: 548  HAPPALATPSPEEGEIQ 564
             A P      PE+ +++
Sbjct: 1234 AAMPPQIIQFPEDQKVR 1250



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVHVKDEGEF 444
           V EGQ     C +   P  +++W  G++ L PS      + + + VLE+  V+  D G +
Sbjct: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231

Query: 445 TCRAQNPLGSQHISLSLSLQ 464
           TC   N  G   +S  LS+Q
Sbjct: 232 TCLVVNGSGKASMSAELSIQ 251



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 12/119 (10%)

Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417
           +L+ S+  Q   + V +   + S+ L++    +V+EGQ   L C+V   P  R++W    
Sbjct: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKD---CAVIEGQDFVLQCSVRGTPVPRITWLLNG 551

Query: 418 LTLSPSQSS-NLGVLELPRVHV-----KDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470
             +  ++S+   GV EL   H+     +D G +TC A+N LG    S  +++  + + +
Sbjct: 552 QPIQYARSTCEAGVAEL---HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 8/100 (8%)

Query: 389 LSVLEGQSLHLVCAVDSNPPARLSW-------TWGSLTLSPSQSSNLGVLELPRVHVKDE 441
           L + EG +      V   P  +++W       T G   L          L +  VH +D 
Sbjct: 42  LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101

Query: 442 GEFTCRAQNPLGSQHISLSLSLQNEYTGKM-RPISGVTLG 480
           G++TC A N  G++ +++ L+++  +  ++ +P+   TLG
Sbjct: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 20/140 (14%)

Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392
           P+D GT  TC+     AG   T+AV L +  P           DGT    +    +++  
Sbjct: 687 PEDTGT-YTCEAW-NSAGEVRTQAV-LTVQEPH----------DGTQPWFISKPRSVTAS 733

Query: 393 EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS-------QSSNLGVLELPRVHVKDEGEFT 445
            GQS+ + CA+  +P   + W      L          Q+ ++  L L +V     G++ 
Sbjct: 734 LGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYE 793

Query: 446 CRAQNPLGSQHISLSLSLQN 465
              +N +G     +SL LQN
Sbjct: 794 ILLKNRVGECSCQVSLMLQN 813



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 10/98 (10%)

Query: 380  STTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGV-------LE 432
            S T+R+   L V+EG +    C ++  P   + W     ++  S+   +         L 
Sbjct: 1812 SKTIRD---LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 433  LPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470
            +  V   D+ ++TC+A N LG    +  L ++    G+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906


>gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens]
          Length = 328

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 35/218 (16%)

Query: 139 VNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIP 198
           +N         R+ ++VP  V+ + G    +PC+  +PH ++    P+   W    A  P
Sbjct: 32  LNTEVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHPHRHY--DGPLTAIW---RAGEP 86

Query: 199 WDIPVATNTPSGKVQE------DTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVER 252
           +  P      + +  E        HGRF LLG+P+ N+ SL +      D  +Y+ +VE 
Sbjct: 87  YAGPQVFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEF 146

Query: 253 GSRKWNYIYDK------LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPT 306
                  ++D+      + +HVTA   +   S+       H     C+     E   PP 
Sbjct: 147 AGD----VHDRYESRHGVRLHVTAAPRIVNISV--LPSPAHAFRALCT----AEGEPPPA 196

Query: 307 ITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQV 344
           + W G ++         +S+ ++    + HG  +T ++
Sbjct: 197 LAWSGPALG--------NSLAAVRSPREGHGHLVTAEL 226



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 19/125 (15%)

Query: 378 TASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSL------TLSPSQS-SNLGV 430
           TA+  + N S L      +   +C  +  PP  L+W+  +L        SP +   +L  
Sbjct: 165 TAAPRIVNISVLPS-PAHAFRALCTAEGEPPPALAWSGPALGNSLAAVRSPREGHGHLVT 223

Query: 431 LELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGA--FGGAGAT 488
            ELP   +  +G +TC A N LG    S+       Y  +    SG +  A   G  G  
Sbjct: 224 AELPA--LTHDGRYTCTAANSLGRSEASV-------YLFRFHGASGASTVALLLGALGFK 274

Query: 489 ALVFL 493
           AL+ L
Sbjct: 275 ALLLL 279


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 65/237 (27%), Positives = 86/237 (36%), Gaps = 43/237 (18%)

Query: 233  LSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLE----SGHP 288
            L I++A+  D G Y  +V       N   + +      +   PTF  P T      +G P
Sbjct: 1897 LEIQEAQVSDKGLYSCKVS------NVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP 1950

Query: 289  RNLTCSVPWACEQGTP-PTITW----MGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTC 342
              LTC V      G P PT+TW    M    S++   ++R   L L   QP   GT  TC
Sbjct: 1951 LVLTCDV-----SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTC 2004

Query: 343  QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402
                  A       V +        L     +  G A           VLEGQ + L C 
Sbjct: 2005 VAENTQAEARKDFVVAV--------LVAPRIRSSGVAREH-------HVLEGQEVRLDCE 2049

Query: 403  VDSNPPARLSWTWGSLTLSPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLG 453
             D  PP  ++W      L      +L      G L L  +   D G +TC A NP G
Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2106



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 104/458 (22%), Positives = 169/458 (36%), Gaps = 96/458 (20%)

Query: 28   MQKSVTVQEGLCVSVLCSFS-YPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQ 86
            +++ + V +G    ++C+ + +PQ   T        WF+ G  ++R              
Sbjct: 1260 LEEVIKVLDGQTAHLMCNVTGHPQPKLT--------WFKDGRPLARG------------- 1298

Query: 87   EETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQD 146
                D  H+  D       L +     S AG Y  C+    +    K+ QLSV +  +  
Sbjct: 1299 ----DAHHISPD----GVLLQVLQANLSSAGHYS-CIAANAVGEKTKHFQLSVLLAPT-- 1347

Query: 147  LLSRYRLEVPESVTVQEGLCVSVPCSVL-YPHYNWTASSPVYGSWFKEGADIPWDIPVAT 205
            +L        E VTV     +S+ C  L +P  N T        W K+GA  P++     
Sbjct: 1348 ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNIT--------WMKDGA--PFEASRNI 1397

Query: 206  NTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDK 263
                G     THG              L I +A+K D+G+Y   V  E G    NY  + 
Sbjct: 1398 QLLPG-----THG--------------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1438

Query: 264  LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITW----MGASVSSLDP 319
            L     +++        G  E     N T ++        PPTI W       + SS   
Sbjct: 1439 LIP--PSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 1496

Query: 320  TITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQ--GD 376
             +    +L + P Q  D G  L     + G      +   + I  PP      +FQ  GD
Sbjct: 1497 VLGEGRLLQIQPTQVSDSGRYLCVATNVAGED---DQDFNVLIQVPP------MFQKVGD 1547

Query: 377  GTASTTL-------RNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN 427
             +A+  +       R G      ++E    +L C  ++ PP  L+W      LS     +
Sbjct: 1548 FSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVS 1607

Query: 428  L----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSL 461
            +     VL++P V  ++ G ++C+A N +G   +   L
Sbjct: 1608 VLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 1645



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 18/111 (16%)

Query: 359  LNISYPPQNLTMTVFQG-DGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417
            +N+  PP     T+ QG DG+ +   R G  ++        +VC V  +PP  +SW    
Sbjct: 2114 VNVLVPP-----TIKQGADGSGTLVSRPGELVT--------MVCPVRGSPPIHVSWLKDG 2160

Query: 418  LTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            L L  SQ + L      L + +V + D G FTC A +P G    + +L +Q
Sbjct: 2161 LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2211



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 62/243 (25%), Positives = 93/243 (38%), Gaps = 39/243 (16%)

Query: 233 LSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRN 290
           L I  A+  D+G Y        GS +  Y    L V+V     +P  S+PG +    P  
Sbjct: 750 LRIEQAQLSDAGSYRCVASNVAGSTELRY---GLRVNVPPRITLPP-SLPGPVLVNTPVR 805

Query: 291 LTCSVPWACEQGTPPTITWM--GASVSSLDP----TITRSSMLSLIPQPQDHGTSLTCQV 344
           LTC+   A      PT+ W+  G  VS              +L+L           +C V
Sbjct: 806 LTCNATGA----PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC-V 860

Query: 345 TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404
            +   G      V L +  PP               + L     +SV+  +S+ L C   
Sbjct: 861 AVSAVGEDRQDVV-LQVHMPP---------------SILGEELNVSVVANESVALECQSH 904

Query: 405 SNPPARLSWTWGSLTLSPSQ----SSNLGVLELPRVHVKDEGEFTCRAQNPLG--SQHIS 458
           + PP  LSW      L P      S++  +L++ R  V D G +TC A N  G   +H +
Sbjct: 905 AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYN 964

Query: 459 LSL 461
           L++
Sbjct: 965 LNV 967



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 41/263 (15%)

Query: 222  LLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDKLSVHVTALTHMPTFSI 279
            LL        SL +     GDSG Y      E G  + ++      + V    H+     
Sbjct: 2256 LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF-----QLTVMEPPHIEDSGQ 2310

Query: 280  PG--TLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLSLIPQPQ 334
            P   +L  G P  L C       QGTP P ITW   G +++ L+     +S  + + + +
Sbjct: 2311 PTELSLTPGAPMELLCDA-----QGTPQPNITWHKDGQALTRLE----NNSRATRVLRVR 2361

Query: 335  DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394
            D G   TC    P   +   ++ R+ +  PP  +        G        G A     G
Sbjct: 2362 DAGL-YTCLAESPAGAIE--KSFRVRVQAPPNIV--------GPRGPRFVVGLA----PG 2406

Query: 395  QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEFTCRAQN 450
            Q L L C+V++ P  +++W    + L     +        L+L  +   D G+++C A+N
Sbjct: 2407 Q-LVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 2465

Query: 451  PLGSQHISLSLSLQNEYTGKMRP 473
              GS  ++  + +    T +  P
Sbjct: 2466 AAGSTSVAFRVEIHTVPTIRSGP 2488



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 69/294 (23%), Positives = 111/294 (37%), Gaps = 62/294 (21%)

Query: 189 SWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYF 248
           +WFK+GA +P          S KV     GR L LG  Q+++  +    A          
Sbjct: 344 TWFKDGALLP---------TSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA---- 390

Query: 249 QVERGSRKWNYIYDKLSVHVTALTHMPTFSIPG------TLESGHPRNLTCSVPWACEQG 302
             E+ +R        L V+V      PT    G         +G P  L C       +G
Sbjct: 391 -AEKATR--------LDVYVP-----PTIEGAGGRPYVVKAVAGRPVALECVA-----RG 431

Query: 303 TP-PTITW----MGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357
            P PT++W    +  + S+     T  S+L L    +      +C  + P     +  +V
Sbjct: 432 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV 491

Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWG- 416
            + +  PPQ L   V +G G  +T +          GQ L L C    +P   + W    
Sbjct: 492 EVQV--PPQLL---VAEGLGQVTTIV----------GQPLELPCQASGSPVPTIQWLQNG 536

Query: 417 --SLTLSPSQSSNLG-VLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEY 467
             +  L+  Q ++ G  L +  V +   G F C+A N  G+    + +S+  E+
Sbjct: 537 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEW 590



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 6/81 (7%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEF 444
            + VL+GQ+ HL+C V  +P  +L+W      L+   + ++     +L++ + ++   G +
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1323

Query: 445  TCRAQNPLG--SQHISLSLSL 463
            +C A N +G  ++H  LS+ L
Sbjct: 1324 SCIAANAVGEKTKHFQLSVLL 1344



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/217 (29%), Positives = 89/217 (41%), Gaps = 37/217 (17%)

Query: 279  IPGTLESGHPRNLTCSVPWA---CE-QGTP-PTITWM--GASVSSLDPTITRSSMLSLIP 331
            +P  +E+G P   T     A   C+ +G+P P ITW   G  VS  +   T      L+ 
Sbjct: 2845 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 2904

Query: 332  ---QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388
               + QD GT  TC  T   A     R V L I      L + VF       TTL    +
Sbjct: 2905 KNLEGQDAGT-YTC--TAENAVGRARRRVHLTI------LVLPVF-------TTLPGDRS 2948

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV--KDEGEFTC 446
            L +  G  L L CA   +P  R+ WT     ++   S   G   L R  V  +D G + C
Sbjct: 2949 LRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC 3006

Query: 447  RAQNPLGSQ------HISLSLSLQNE-YTGKMRPISG 476
             A+N +G        H+  +  LQ E ++  + P+ G
Sbjct: 3007 WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 3043



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 56/298 (18%)

Query: 180 WTASSPV-YGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 238
           WT+  P     W K+        PV    P  +VQED                 L I  +
Sbjct: 240 WTSGVPTPQVEWTKDRQ------PVLPGGPHLQVQEDGQ--------------VLRITGS 279

Query: 239 RKGDSGKYYFQVERGSRKWNYIYD-KLSVHVTALTHMPTFSIPGTLESGHPRNLTCS-VP 296
             GD G+Y  Q    S       D +L VH       PT  I G+ E+G    +    V 
Sbjct: 280 HVGDEGRY--QCVAFSPAGQQARDFQLRVHAP-----PT--IWGSNETGEVAVMEDHLVQ 330

Query: 297 WACE-QGTP-PTITWM--GASV-SSLDPTITRSSMLSLIPQPQDHGTSL-TCQVTLPGAG 350
             CE +G P P ITW   GA + +S     TR      + + Q     + TC+ +   A 
Sbjct: 331 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS--NAV 388

Query: 351 VTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPAR 410
               +A RL++  PP        +G G     ++       + G+ + L C    +P   
Sbjct: 389 GAAEKATRLDVYVPP------TIEGAGGRPYVVK------AVAGRPVALECVARGHPSPT 436

Query: 411 LSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
           LSW    L ++ S  S L     VL L        G ++C A +P G   +  S+ +Q
Sbjct: 437 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 494



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 80/383 (20%), Positives = 131/383 (34%), Gaps = 75/383 (19%)

Query: 120  VFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL----CVSVPCSVLY 175
            V  +E+  +     Y  ++ NV  S +L    R+ VP  +T+   L     V+ P  +  
Sbjct: 749  VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 808

Query: 176  PHYNWTASSPVYGSWFKEGADI-PWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLS 234
               N T +      W K+G  + P   P     P G+V                    L+
Sbjct: 809  ---NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV--------------------LT 845

Query: 235  IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCS 294
            +  AR  DSG+Y         +     D+  V +    HMP   +   L      N + +
Sbjct: 846  LASARASDSGRYSCVAVSAVGE-----DRQDVVLQV--HMPPSILGEELNVSVVANESVA 898

Query: 295  VPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGV--- 351
            +        PP ++W                   L P+P  H ++    + +  A V   
Sbjct: 899  LECQSHAMPPPVLSWW-------------KDGRPLEPRPGVHLSADKALLQVDRADVWDA 945

Query: 352  ------TMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDS 405
                   + +A R    Y        VF         LR    L+V EG    L C    
Sbjct: 946  GHYTCEALNQAGRSEKHYNLNVWVAPVFP--------LRESHTLTVREGHPTSLSCECRG 997

Query: 406  NPPARLSWTWGSLTLSPSQSSNLG-------VLELPRVHVKDEGEFTCRAQNPLG--SQH 456
             P  ++SW      L P + + L        +L L +  +  EG +TC   N +G  SQ 
Sbjct: 998  VPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQD 1056

Query: 457  ISLSLSLQNEYTGKMRPISGVTL 479
            + L + +  +  G   P + V++
Sbjct: 1057 LQLEVHVPPQIAGPREPPTQVSV 1079



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 43/188 (22%), Positives = 66/188 (35%), Gaps = 19/188 (10%)

Query: 286 GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLD--PTITRSSMLSLIPQPQDHGTSL 340
           G P  L C        G+P PTI W+  G     L      ++ + L +     DH    
Sbjct: 513 GQPLELPCQA-----SGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLF 567

Query: 341 TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 400
            CQ T           V ++  + P  L + +    G       + S+        +H  
Sbjct: 568 ACQATNEAGTAGAEVEVSVHGEWAPGVLEVPI----GQYHWGXEHHSSFPAACDPPVHRG 623

Query: 401 CAVDSNPPARLSWT-----WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455
                 PP    W      WG  T  P   S    L++ +V ++DEG +TC A N  G  
Sbjct: 624 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 683

Query: 456 HISLSLSL 463
              ++L +
Sbjct: 684 KREVALKV 691



 Score = 36.2 bits (82), Expect = 0.088
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWG----SLTLSPSQSSNLGVLELPRVHVKDEGEFT 445
           +VLE  S+ L C     PP  +SW  G    S  +  + S +  VL + +  + D G + 
Sbjct: 705 AVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 764

Query: 446 CRAQNPLGSQHISLSL 461
           C A N  GS  +   L
Sbjct: 765 CVASNVAGSTELRYGL 780



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 3/95 (3%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFT 445
            ++V  G  + L C     P   + W      L  S+       G L L  V   D G + 
Sbjct: 3127 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 3186

Query: 446  CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480
            C A N LGS      L ++ E  G    ++GV  G
Sbjct: 3187 CVAHNLLGSATARAFLVVRGEPQGSWGSMTGVING 3221



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444
            ++V    ++ L C    NP   +SW    L  SPS    +     VL++    V D   +
Sbjct: 1664 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASY 1723

Query: 445  TCRAQNPLGSQHISLSLSLQ 464
             C A+N  GS     +L +Q
Sbjct: 1724 MCVAENQAGSAEKLFTLRVQ 1743



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 46/213 (21%), Positives = 80/213 (37%), Gaps = 38/213 (17%)

Query: 282  TLESGHPRNLTCSVPWACEQGTP-PTITWM---------GASVSSLDPTITRSSMLSLIP 331
            T+  GHP +L+C       +G P P I+W          GA +  +   + R   L    
Sbjct: 982  TVREGHPTSLSCEC-----RGVPFPKISWRKDGQPLPGEGAGLQHVS-AVGRLLYLGQAQ 1035

Query: 332  QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSV 391
              Q+   +  C   +  +    ++ ++L +  PPQ        G     T       +SV
Sbjct: 1036 LAQEGTYTCECSNVVGNS----SQDLQLEVHVPPQ------IAGPREPPT------QVSV 1079

Query: 392  LEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---QSSNLG-VLELPRVHVKDEGEFTCR 447
            ++     L C     PP  ++W      +      Q  N G  L + R      G ++C 
Sbjct: 1080 VQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCV 1139

Query: 448  AQNPLG--SQHISLSLSLQNEYTGKMRPISGVT 478
            A+N  G   +   LS+ +  E  G + P++ +T
Sbjct: 1140 AENLAGRAERKFELSVLVPPELIGDLDPLTNIT 1172



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444
            ++ +   S+ L C V ++P   ++W   S  LS  +   L      L+L R  + D G +
Sbjct: 1756 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMY 1815

Query: 445  TCRAQNPLGSQHISLSLSL 463
            TC A N  G     + LS+
Sbjct: 1816 TCEALNAAGRDQKLVQLSV 1834



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 43/185 (23%), Positives = 67/185 (36%), Gaps = 30/185 (16%)

Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360
           +G  P  +WMG +VS +D  + R     L     D G S  C  +       +   +R+N
Sbjct: 730 KGHQPVSSWMGVTVS-VDGRVLRIEQAQL----SDAG-SYRCVASNVAGSTELRYGLRVN 783

Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420
           +  PP+               TL       VL    + L C     P   L W      +
Sbjct: 784 V--PPR--------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPV 827

Query: 421 SPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLGS--QHISLSLSLQNEYTGKMR 472
           SP+ +  L       VL L      D G ++C A + +G   Q + L + +     G+  
Sbjct: 828 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEEL 887

Query: 473 PISGV 477
            +S V
Sbjct: 888 NVSVV 892



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 369  TMTVFQGDGTASTTLRNGS-ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---- 423
            T   F+ +     T+R+G  A++V   Q+  L C  D  P   +SW    + L P     
Sbjct: 2470 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529

Query: 424  QSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
            +    G L +  V  +D G + C A N  GS
Sbjct: 2530 EILPEGSLRIQPVLAQDAGHYLCLASNSAGS 2560



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%)

Query: 397  LHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPL 452
            L L+C     PP  + W  G   +SP + + L     +L++ +   +D G ++C A N  
Sbjct: 1179 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1238

Query: 453  GSQHISLSL------SLQNE 466
            G    + S+      S++NE
Sbjct: 1239 GEARRNFSVEVLVPPSIENE 1258



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 386  GSALSVLE---GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVK 439
            G A S L    G S+ L C V  +P   + W    L L  S   +    G L + R    
Sbjct: 3031 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 3090

Query: 440  DEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRP 473
            D G + C A+N +G     + L LQ+    ++ P
Sbjct: 3091 DAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 3124



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 7/82 (8%)

Query: 381 TTLRNGSALSVL--EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS----QSSNLG-VLEL 433
           + L  G+A  VL   G  + L C     P  ++ WT     + P     Q    G VL +
Sbjct: 217 SVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRI 276

Query: 434 PRVHVKDEGEFTCRAQNPLGSQ 455
              HV DEG + C A +P G Q
Sbjct: 277 TGSHVGDEGRYQCVAFSPAGQQ 298



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 4/81 (4%)

Query: 388  ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGE 443
            A+ V  G    L C  D+ P   ++W      L  +Q +        LE+    V D+G 
Sbjct: 1850 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 1909

Query: 444  FTCRAQNPLGSQHISLSLSLQ 464
            ++C+  N  G    + +L++Q
Sbjct: 1910 YSCKVSNVAGEAVRTFTLTVQ 1930


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 65/237 (27%), Positives = 86/237 (36%), Gaps = 43/237 (18%)

Query: 233  LSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLE----SGHP 288
            L I++A+  D G Y  +V       N   + +      +   PTF  P T      +G P
Sbjct: 3088 LEIQEAQVSDKGLYSCKVS------NVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP 3141

Query: 289  RNLTCSVPWACEQGTP-PTITW----MGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTC 342
              LTC V      G P PT+TW    M    S++   ++R   L L   QP   GT  TC
Sbjct: 3142 LVLTCDV-----SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTC 3195

Query: 343  QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402
                  A       V +        L     +  G A           VLEGQ + L C 
Sbjct: 3196 VAENTQAEARKDFVVAV--------LVAPRIRSSGVAREH-------HVLEGQEVRLDCE 3240

Query: 403  VDSNPPARLSWTWGSLTLSPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLG 453
             D  PP  ++W      L      +L      G L L  +   D G +TC A NP G
Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 3297



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 5/97 (5%)

Query: 369 TMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLT--LSPSQSS 426
           T+T++  D  + + +   + + V  G+   LVC     PP R+ W  G L   L+P  SS
Sbjct: 689 TVTLYYTDPPSVSAVN--AVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSS 746

Query: 427 NLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463
           + G L +P    +D G +TCRA N LG     + L++
Sbjct: 747 S-GKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 104/458 (22%), Positives = 169/458 (36%), Gaps = 96/458 (20%)

Query: 28   MQKSVTVQEGLCVSVLCSFS-YPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQ 86
            +++ + V +G    ++C+ + +PQ   T        WF+ G  ++R              
Sbjct: 2451 LEEVIKVLDGQTAHLMCNVTGHPQPKLT--------WFKDGRPLARG------------- 2489

Query: 87   EETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQD 146
                D  H+  D       L +     S AG Y  C+    +    K+ QLSV +  +  
Sbjct: 2490 ----DAHHISPD----GVLLQVLQANLSSAGHYS-CIAANAVGEKTKHFQLSVLLAPT-- 2538

Query: 147  LLSRYRLEVPESVTVQEGLCVSVPCSVL-YPHYNWTASSPVYGSWFKEGADIPWDIPVAT 205
            +L        E VTV     +S+ C  L +P  N T        W K+GA  P++     
Sbjct: 2539 ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNIT--------WMKDGA--PFEASRNI 2588

Query: 206  NTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDK 263
                G     THG              L I +A+K D+G+Y   V  E G    NY  + 
Sbjct: 2589 QLLPG-----THG--------------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 2629

Query: 264  LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITW----MGASVSSLDP 319
            L     +++        G  E     N T ++        PPTI W       + SS   
Sbjct: 2630 LIP--PSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 2687

Query: 320  TITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQ--GD 376
             +    +L + P Q  D G  L     + G      +   + I  PP      +FQ  GD
Sbjct: 2688 VLGEGRLLQIQPTQVSDSGRYLCVATNVAGED---DQDFNVLIQVPP------MFQKVGD 2738

Query: 377  GTASTTL-------RNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN 427
             +A+  +       R G      ++E    +L C  ++ PP  L+W      LS     +
Sbjct: 2739 FSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVS 2798

Query: 428  L----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSL 461
            +     VL++P V  ++ G ++C+A N +G   +   L
Sbjct: 2799 VLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 2836



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 100/408 (24%), Positives = 145/408 (35%), Gaps = 93/408 (22%)

Query: 101  NKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTA-SQDLLSRYRLEVPESV 159
            +K+ TL I      DAG YV C     + ++ +  +LSVN  A S+ +   Y L    S+
Sbjct: 1026 SKEGTLLIAQPSAQDAGAYV-CTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSL 1084

Query: 160  TVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKE--GADIPWDIP--------------- 202
             + +   V V  S    HY  TAS+P   +  +   G  +P  +                
Sbjct: 1085 RLAQ---VQVGDS---GHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALD 1138

Query: 203  ---VATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVER--GSRKW 257
               VA   P  ++     G  L    PQ    S+     R  D+G+Y  +     G   W
Sbjct: 1139 LNCVAEGNPEPQLSWSKDGVVLQGRGPQG---SVHFAAIRTSDAGRYRCEASNSAGVDAW 1195

Query: 258  NYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTP-PTITWM-GASVS 315
                 ++ + V    H       G LE     N +   P    +GTP P +TW  G S  
Sbjct: 1196 -----EVELRVLEPPHWGADETSGLLERVAGENASLPCP---ARGTPKPQVTWRKGPSSE 1247

Query: 316  SLD-----PTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTM 370
             L        +   S+      P D G    CQ T    G T  RA +L +  PP     
Sbjct: 1248 PLHGQPGVAVLEEGSLFLASVSPADSG-DYECQATNE-VGSTSRRA-KLVVYVPPS---- 1300

Query: 371  TVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT---------------- 414
               + DG  +        +S + GQSL L C  +  P   + W                 
Sbjct: 1301 --IREDGRKAN-------VSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYG 1351

Query: 415  ----WGSL----TLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
                WG +     L   QS     L  PR+   D G ++CRA+N  G+
Sbjct: 1352 WDLGWGQVGGHRLLDEGQS-----LHFPRIQEGDSGLYSCRAENQAGT 1394



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 18/111 (16%)

Query: 359  LNISYPPQNLTMTVFQG-DGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417
            +N+  PP     T+ QG DG+ +   R G  ++        +VC V  +PP  +SW    
Sbjct: 3305 VNVLVPP-----TIKQGADGSGTLVSRPGELVT--------MVCPVRGSPPIHVSWLKDG 3351

Query: 418  LTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            L L  SQ + L      L + +V + D G FTC A +P G    + +L +Q
Sbjct: 3352 LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 3402



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 62/243 (25%), Positives = 93/243 (38%), Gaps = 39/243 (16%)

Query: 233  LSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRN 290
            L I  A+  D+G Y        GS +  Y    L V+V     +P  S+PG +    P  
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRY---GLRVNVPPRITLPP-SLPGPVLVNTPVR 1996

Query: 291  LTCSVPWACEQGTPPTITWM--GASVSSLDP----TITRSSMLSLIPQPQDHGTSLTCQV 344
            LTC+   A      PT+ W+  G  VS              +L+L           +C V
Sbjct: 1997 LTCNATGA----PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC-V 2051

Query: 345  TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404
             +   G      V L +  PP               + L     +SV+  +S+ L C   
Sbjct: 2052 AVSAVGEDRQDVV-LQVHMPP---------------SILGEELNVSVVANESVALECQSH 2095

Query: 405  SNPPARLSWTWGSLTLSPSQ----SSNLGVLELPRVHVKDEGEFTCRAQNPLG--SQHIS 458
            + PP  LSW      L P      S++  +L++ R  V D G +TC A N  G   +H +
Sbjct: 2096 AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYN 2155

Query: 459  LSL 461
            L++
Sbjct: 2156 LNV 2158



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 41/263 (15%)

Query: 222  LLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDKLSVHVTALTHMPTFSI 279
            LL        SL +     GDSG Y      E G  + ++      + V    H+     
Sbjct: 3447 LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF-----QLTVMEPPHIEDSGQ 3501

Query: 280  PG--TLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLSLIPQPQ 334
            P   +L  G P  L C       QGTP P ITW   G +++ L+     +S  + + + +
Sbjct: 3502 PTELSLTPGAPMELLCDA-----QGTPQPNITWHKDGQALTRLE----NNSRATRVLRVR 3552

Query: 335  DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394
            D G   TC    P   +   ++ R+ +  PP  +        G        G A     G
Sbjct: 3553 DAGL-YTCLAESPAGAIE--KSFRVRVQAPPNIV--------GPRGPRFVVGLA----PG 3597

Query: 395  QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEFTCRAQN 450
            Q L L C+V++ P  +++W    + L     +        L+L  +   D G+++C A+N
Sbjct: 3598 Q-LVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 3656

Query: 451  PLGSQHISLSLSLQNEYTGKMRP 473
              GS  ++  + +    T +  P
Sbjct: 3657 AAGSTSVAFRVEIHTVPTIRSGP 3679



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 69/294 (23%), Positives = 111/294 (37%), Gaps = 62/294 (21%)

Query: 189  SWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYF 248
            +WFK+GA +P          S KV     GR L LG  Q+++  +    A          
Sbjct: 1535 TWFKDGALLP---------TSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA---- 1581

Query: 249  QVERGSRKWNYIYDKLSVHVTALTHMPTFSIPG------TLESGHPRNLTCSVPWACEQG 302
              E+ +R        L V+V      PT    G         +G P  L C       +G
Sbjct: 1582 -AEKATR--------LDVYVP-----PTIEGAGGRPYVVKAVAGRPVALECVA-----RG 1622

Query: 303  TP-PTITW----MGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357
             P PT++W    +  + S+     T  S+L L    +      +C  + P     +  +V
Sbjct: 1623 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV 1682

Query: 358  RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWG- 416
             + +  PPQ L   V +G G  +T +          GQ L L C    +P   + W    
Sbjct: 1683 EVQV--PPQLL---VAEGLGQVTTIV----------GQPLELPCQASGSPVPTIQWLQNG 1727

Query: 417  --SLTLSPSQSSNLG-VLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEY 467
              +  L+  Q ++ G  L +  V +   G F C+A N  G+    + +S+  E+
Sbjct: 1728 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEW 1781



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 6/81 (7%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEF 444
            + VL+GQ+ HL+C V  +P  +L+W      L+   + ++     +L++ + ++   G +
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 2514

Query: 445  TCRAQNPLG--SQHISLSLSL 463
            +C A N +G  ++H  LS+ L
Sbjct: 2515 SCIAANAVGEKTKHFQLSVLL 2535



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/217 (29%), Positives = 89/217 (41%), Gaps = 37/217 (17%)

Query: 279  IPGTLESGHPRNLTCSVPWA---CE-QGTP-PTITWM--GASVSSLDPTITRSSMLSLIP 331
            +P  +E+G P   T     A   C+ +G+P P ITW   G  VS  +   T      L+ 
Sbjct: 4036 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 4095

Query: 332  ---QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388
               + QD GT  TC  T   A     R V L I      L + VF       TTL    +
Sbjct: 4096 KNLEGQDAGT-YTC--TAENAVGRARRRVHLTI------LVLPVF-------TTLPGDRS 4139

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV--KDEGEFTC 446
            L +  G  L L CA   +P  R+ WT     ++   S   G   L R  V  +D G + C
Sbjct: 4140 LRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC 4197

Query: 447  RAQNPLGSQ------HISLSLSLQNE-YTGKMRPISG 476
             A+N +G        H+  +  LQ E ++  + P+ G
Sbjct: 4198 WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 4234



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 65/278 (23%), Positives = 98/278 (35%), Gaps = 42/278 (15%)

Query: 204 ATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDK 263
           A+  P  +V     G  ++L    +++  L I  A++ D+G Y        R  N + D 
Sbjct: 721 ASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYT------CRAVNELGDA 774

Query: 264 LSVHVTALTHMPTFS-IPG--TLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPT 320
            +    A+ H P  + +P   T+E G    L C          PPT+TW       L   
Sbjct: 775 SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGR----PPPTVTWRRGDGQPLGLR 830

Query: 321 ITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAS 380
           +               G     +   P +GV    +V      P       VF      +
Sbjct: 831 L---------------GAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 875

Query: 381 TTLRNGSA----------LSVLEGQSLHLVCAVDSNPPA-RLSWTWGSLTLSPSQSSNL- 428
             +  G A          + VLEGQ + L C V +  P     W      L P    ++ 
Sbjct: 876 RLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIR 935

Query: 429 --GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
             G L L R   +  G ++C A N  GSQH  + L +Q
Sbjct: 936 ADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 973



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 56/298 (18%)

Query: 180  WTASSPV-YGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 238
            WT+  P     W K+        PV    P  +VQED                 L I  +
Sbjct: 1431 WTSGVPTPQVEWTKDRQ------PVLPGGPHLQVQEDGQ--------------VLRITGS 1470

Query: 239  RKGDSGKYYFQVERGSRKWNYIYD-KLSVHVTALTHMPTFSIPGTLESGHPRNLTCS-VP 296
              GD G+Y  Q    S       D +L VH       PT  I G+ E+G    +    V 
Sbjct: 1471 HVGDEGRY--QCVAFSPAGQQARDFQLRVHAP-----PT--IWGSNETGEVAVMEDHLVQ 1521

Query: 297  WACE-QGTP-PTITWM--GASV-SSLDPTITRSSMLSLIPQPQDHGTSL-TCQVTLPGAG 350
              CE +G P P ITW   GA + +S     TR      + + Q     + TC+ +   A 
Sbjct: 1522 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS--NAV 1579

Query: 351  VTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPAR 410
                +A RL++  PP        +G G     ++       + G+ + L C    +P   
Sbjct: 1580 GAAEKATRLDVYVPP------TIEGAGGRPYVVK------AVAGRPVALECVARGHPSPT 1627

Query: 411  LSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            LSW    L ++ S  S L     VL L        G ++C A +P G   +  S+ +Q
Sbjct: 1628 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 1685



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 80/380 (21%), Positives = 131/380 (34%), Gaps = 69/380 (18%)

Query: 120  VFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL----CVSVPCSVLY 175
            V  +E+  +     Y  ++ NV  S +L    R+ VP  +T+   L     V+ P  +  
Sbjct: 1940 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 1999

Query: 176  PHYNWTASSPVYGSWFKEGADI-PWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLS 234
               N T +      W K+G  + P   P     P G+V                    L+
Sbjct: 2000 ---NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV--------------------LT 2036

Query: 235  IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCS 294
            +  AR  DSG+Y         +     D+  V +    HMP   +   L      N + +
Sbjct: 2037 LASARASDSGRYSCVAVSAVGE-----DRQDVVLQV--HMPPSILGEELNVSVVANESVA 2089

Query: 295  VPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGV--- 351
            +        PP ++W                   L P+P  H ++    + +  A V   
Sbjct: 2090 LECQSHAMPPPVLSWW-------------KDGRPLEPRPGVHLSADKALLQVDRADVWDA 2136

Query: 352  ---TMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPP 408
               T     +   S    NL + V          LR    L+V EG    L C     P 
Sbjct: 2137 GHYTCEALNQAGHSEKHYNLNVWV-----APVFPLRESHTLTVREGHPTSLSCECRGVPF 2191

Query: 409  ARLSWTWGSLTLSPSQSSNLG-------VLELPRVHVKDEGEFTCRAQNPLG--SQHISL 459
             ++SW      L P + + L        +L L +  +  EG +TC   N +G  SQ + L
Sbjct: 2192 PKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQL 2250

Query: 460  SLSLQNEYTGKMRPISGVTL 479
             + +  +  G   P + V++
Sbjct: 2251 EVHVPPQIAGPREPPTQVSV 2270



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 43/188 (22%), Positives = 66/188 (35%), Gaps = 19/188 (10%)

Query: 286  GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLD--PTITRSSMLSLIPQPQDHGTSL 340
            G P  L C        G+P PTI W+  G     L      ++ + L +     DH    
Sbjct: 1704 GQPLELPCQA-----SGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLF 1758

Query: 341  TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 400
             CQ T           V ++  + P  L + +    G       + S+        +H  
Sbjct: 1759 ACQATNEAGTAGAEVEVSVHGEWAPGVLEVPI----GQYHWGXEHHSSFPAACDPPVHRG 1814

Query: 401  CAVDSNPPARLSWT-----WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455
                  PP    W      WG  T  P   S    L++ +V ++DEG +TC A N  G  
Sbjct: 1815 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 1874

Query: 456  HISLSLSL 463
               ++L +
Sbjct: 1875 KREVALKV 1882



 Score = 36.2 bits (82), Expect = 0.088
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 390  SVLEGQSLHLVCAVDSNPPARLSWTWG----SLTLSPSQSSNLGVLELPRVHVKDEGEFT 445
            +VLE  S+ L C     PP  +SW  G    S  +  + S +  VL + +  + D G + 
Sbjct: 1896 AVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 1955

Query: 446  CRAQNPLGSQHISLSL 461
            C A N  GS  +   L
Sbjct: 1956 CVASNVAGSTELRYGL 1971



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 3/95 (3%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFT 445
            ++V  G  + L C     P   + W      L  S+       G L L  V   D G + 
Sbjct: 4318 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 4377

Query: 446  CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480
            C A N LGS      L ++ E  G    ++GV  G
Sbjct: 4378 CVAHNLLGSATARAFLVVRGEPQGSWGSMTGVING 4412



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444
            ++V    ++ L C    NP   +SW    L  SPS    +     VL++    V D   +
Sbjct: 2855 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASY 2914

Query: 445  TCRAQNPLGSQHISLSLSLQ 464
             C A+N  GS     +L +Q
Sbjct: 2915 MCVAENQAGSAEKLFTLRVQ 2934



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 46/213 (21%), Positives = 80/213 (37%), Gaps = 38/213 (17%)

Query: 282  TLESGHPRNLTCSVPWACEQGTP-PTITWM---------GASVSSLDPTITRSSMLSLIP 331
            T+  GHP +L+C       +G P P I+W          GA +  +   + R   L    
Sbjct: 2173 TVREGHPTSLSCEC-----RGVPFPKISWRKDGQPLPGEGAGLQHVS-AVGRLLYLGQAQ 2226

Query: 332  QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSV 391
              Q+   +  C   +  +    ++ ++L +  PPQ        G     T       +SV
Sbjct: 2227 LAQEGTYTCECSNVVGNS----SQDLQLEVHVPPQ------IAGPREPPT------QVSV 2270

Query: 392  LEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---QSSNLG-VLELPRVHVKDEGEFTCR 447
            ++     L C     PP  ++W      +      Q  N G  L + R      G ++C 
Sbjct: 2271 VQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCV 2330

Query: 448  AQNPLG--SQHISLSLSLQNEYTGKMRPISGVT 478
            A+N  G   +   LS+ +  E  G + P++ +T
Sbjct: 2331 AENLAGRAERKFELSVLVPPELIGDLDPLTNIT 2363



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444
            ++ +   S+ L C V ++P   ++W   S  LS  +   L      L+L R  + D G +
Sbjct: 2947 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMY 3006

Query: 445  TCRAQNPLGSQHISLSLSL 463
            TC A N  G     + LS+
Sbjct: 3007 TCEALNAAGRDQKLVQLSV 3025



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 72/314 (22%), Positives = 102/314 (32%), Gaps = 96/314 (30%)

Query: 158  SVTVQEGLCVSVPCSVLYPHYNWTASSPV-YGSWFKEGADIP----WDIPVATNTPSGKV 212
            +V V EG  VS+PC VL       A  P+    W K+G  +P      I    +    + 
Sbjct: 893  TVRVLEGQPVSLPCIVL-------AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRA 945

Query: 213  QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT 272
             ++  GR+  +    TN      RD            V+   R          +H TA  
Sbjct: 946  LQEHAGRYSCVA---TNTAGSQHRDVE--------LVVQVPPR----------IHPTATH 984

Query: 273  HMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGAS--VSSLDPTITRSSMLSLI 330
            H+    +P +L            P        PTITW   +  ++S  P    S      
Sbjct: 985  HITNEGVPASL------------PCVASGVPAPTITWTKETNALTSRGPHYNVSK----- 1027

Query: 331  PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390
                  GT L  Q +   AG  +  A    + +  Q + ++V            N  ALS
Sbjct: 1028 -----EGTLLIAQPSAQDAGAYVCTATN-TVGFSSQEMRLSV------------NRLALS 1069

Query: 391  VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450
                                  + W    L PS     G L L +V V D G + C A N
Sbjct: 1070 ---------------------KYVWEEYGLLPS-----GSLRLAQVQVGDSGHYECTASN 1103

Query: 451  PLGSQHISLSLSLQ 464
            P GS      L +Q
Sbjct: 1104 PAGSASHRYVLGVQ 1117



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%)

Query: 378  TASTTLRNGSALSVL--EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS----QSSNLG-V 430
            T  + L  G+A  VL   G  + L C     P  ++ WT     + P     Q    G V
Sbjct: 1405 TPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV 1464

Query: 431  LELPRVHVKDEGEFTCRAQNPLGSQ 455
            L +   HV DEG + C A +P G Q
Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQQ 1489



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 43/185 (23%), Positives = 67/185 (36%), Gaps = 30/185 (16%)

Query: 301  QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360
            +G  P  +WMG +VS +D  + R     L     D G S  C  +       +   +R+N
Sbjct: 1921 KGHQPVSSWMGVTVS-VDGRVLRIEQAQL----SDAG-SYRCVASNVAGSTELRYGLRVN 1974

Query: 361  ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420
            +  PP+               TL       VL    + L C     P   L W      +
Sbjct: 1975 V--PPR--------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPV 2018

Query: 421  SPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLGS--QHISLSLSLQNEYTGKMR 472
            SP+ +  L       VL L      D G ++C A + +G   Q + L + +     G+  
Sbjct: 2019 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEEL 2078

Query: 473  PISGV 477
             +S V
Sbjct: 2079 NVSVV 2083



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 369  TMTVFQGDGTASTTLRNGS-ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---- 423
            T   F+ +     T+R+G  A++V   Q+  L C  D  P   +SW    + L P     
Sbjct: 3661 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720

Query: 424  QSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
            +    G L +  V  +D G + C A N  GS
Sbjct: 3721 EILPEGSLRIQPVLAQDAGHYLCLASNSAGS 3751



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%)

Query: 397  LHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPL 452
            L L+C     PP  + W  G   +SP + + L     +L++ +   +D G ++C A N  
Sbjct: 2370 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 2429

Query: 453  GSQHISLSL------SLQNE 466
            G    + S+      S++NE
Sbjct: 2430 GEARRNFSVEVLVPPSIENE 2449



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 386  GSALSVLE---GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVK 439
            G A S L    G S+ L C V  +P   + W    L L  S   +    G L + R    
Sbjct: 4222 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 4281

Query: 440  DEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRP 473
            D G + C A+N +G     + L LQ+    ++ P
Sbjct: 4282 DAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 4315



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 17/72 (23%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 393 EGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFTCRAQ 449
           +G  + + C+    P   +SW+  S  L      ++   G L +  V  +D G ++C+A 
Sbjct: 621 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680

Query: 450 NPLGSQHISLSL 461
           N +G+   +++L
Sbjct: 681 NEVGTDQETVTL 692



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 4/81 (4%)

Query: 388  ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGE 443
            A+ V  G    L C  D+ P   ++W      L  +Q +        LE+    V D+G 
Sbjct: 3041 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 3100

Query: 444  FTCRAQNPLGSQHISLSLSLQ 464
            ++C+  N  G    + +L++Q
Sbjct: 3101 YSCKVSNVAGEAVRTFTLTVQ 3121


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 65/237 (27%), Positives = 86/237 (36%), Gaps = 43/237 (18%)

Query: 233  LSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLE----SGHP 288
            L I++A+  D G Y  +V       N   + +      +   PTF  P T      +G P
Sbjct: 1806 LEIQEAQVSDKGLYSCKVS------NVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP 1859

Query: 289  RNLTCSVPWACEQGTP-PTITW----MGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTC 342
              LTC V      G P PT+TW    M    S++   ++R   L L   QP   GT  TC
Sbjct: 1860 LVLTCDV-----SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTC 1913

Query: 343  QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402
                  A       V +        L     +  G A           VLEGQ + L C 
Sbjct: 1914 VAENTQAEARKDFVVAV--------LVAPRIRSSGVAREH-------HVLEGQEVRLDCE 1958

Query: 403  VDSNPPARLSWTWGSLTLSPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLG 453
             D  PP  ++W      L      +L      G L L  +   D G +TC A NP G
Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2015



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 104/458 (22%), Positives = 170/458 (37%), Gaps = 96/458 (20%)

Query: 28   MQKSVTVQEGLCVSVLCSFS-YPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQ 86
            +++ + V +G    ++C+ + +PQ   T        WF+ G  ++R              
Sbjct: 1169 LEEVIKVLDGQTAHLMCNVTGHPQPKLT--------WFKDGRPLARG------------- 1207

Query: 87   EETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQD 146
                D  H+  D       L +     S AG Y  C+    +    K+ QLSV +  +  
Sbjct: 1208 ----DAHHISPD----GVLLQVLQANLSSAGHYS-CIAANAVGEKTKHFQLSVLLAPT-- 1256

Query: 147  LLSRYRLEVPESVTVQEGLCVSVPCSVL-YPHYNWTASSPVYGSWFKEGADIPWDIPVAT 205
            +L        E VTV     +S+ C  L +P  N T        W K+GA  P++     
Sbjct: 1257 ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNIT--------WMKDGA--PFEASRNI 1306

Query: 206  NTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDK 263
                G     THG              L I +A+K D+G+Y   V  E G    NY  + 
Sbjct: 1307 QLLPG-----THG--------------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1347

Query: 264  LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITW----MGASVSSLDP 319
            L     +++     +  G  E     N T ++        PPTI W       + SS   
Sbjct: 1348 LIP--PSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 1405

Query: 320  TITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQ--GD 376
             +    +L + P Q  D G  L     + G      +   + I  PP      +FQ  GD
Sbjct: 1406 VLGEGRLLQIQPTQVSDSGRYLCVATNVAGED---DQDFNVLIQVPP------MFQKVGD 1456

Query: 377  GTASTTL-------RNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN 427
             +A+  +       R G      ++E    +L C  ++ PP  L+W      LS     +
Sbjct: 1457 FSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVS 1516

Query: 428  L----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSL 461
            +     VL++P V  ++ G ++C+A N +G   +   L
Sbjct: 1517 VLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 1554



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 18/111 (16%)

Query: 359  LNISYPPQNLTMTVFQG-DGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417
            +N+  PP     T+ QG DG+ +   R G  ++        +VC V  +PP  +SW    
Sbjct: 2023 VNVLVPP-----TIKQGADGSGTLVSRPGELVT--------MVCPVRGSPPIHVSWLKDG 2069

Query: 418  LTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
            L L  SQ + L      L + +V + D G FTC A +P G    + +L +Q
Sbjct: 2070 LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2120



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 62/243 (25%), Positives = 93/243 (38%), Gaps = 39/243 (16%)

Query: 233 LSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRN 290
           L I  A+  D+G Y        GS +  Y    L V+V     +P  S+PG +    P  
Sbjct: 659 LRIEQAQLSDAGSYRCVASNVAGSTELRY---GLRVNVPPRITLPP-SLPGPVLVNTPVR 714

Query: 291 LTCSVPWACEQGTPPTITWM--GASVSSLDP----TITRSSMLSLIPQPQDHGTSLTCQV 344
           LTC+   A      PT+ W+  G  VS              +L+L           +C V
Sbjct: 715 LTCNATGA----PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC-V 769

Query: 345 TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404
            +   G      V L +  PP               + L     +SV+  +S+ L C   
Sbjct: 770 AVSAVGEDRQDVV-LQVHMPP---------------SILGEELNVSVVANESVALECQSH 813

Query: 405 SNPPARLSWTWGSLTLSPSQ----SSNLGVLELPRVHVKDEGEFTCRAQNPLG--SQHIS 458
           + PP  LSW      L P      S++  +L++ R  V D G +TC A N  G   +H +
Sbjct: 814 AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYN 873

Query: 459 LSL 461
           L++
Sbjct: 874 LNV 876



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 41/263 (15%)

Query: 222  LLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDKLSVHVTALTHMPTFSI 279
            LL        SL +     GDSG Y      E G  + ++      + V    H+     
Sbjct: 2165 LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF-----QLTVMEPPHIEDSGQ 2219

Query: 280  PG--TLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLSLIPQPQ 334
            P   +L  G P  L C       QGTP P ITW   G +++ L+     +S  + + + +
Sbjct: 2220 PTELSLTPGAPMELLCDA-----QGTPQPNITWHKDGQALTRLE----NNSRATRVLRVR 2270

Query: 335  DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394
            D G   TC    P   +   ++ R+ +  PP  +        G        G A     G
Sbjct: 2271 DAGL-YTCLAESPAGAIE--KSFRVRVQAPPNIV--------GPRGPRFVVGLA----PG 2315

Query: 395  QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEFTCRAQN 450
            Q L L C+V++ P  +++W    + L     +        L+L  +   D G+++C A+N
Sbjct: 2316 Q-LVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 2374

Query: 451  PLGSQHISLSLSLQNEYTGKMRP 473
              GS  ++  + +    T +  P
Sbjct: 2375 AAGSTSVAFRVEIHTVPTIRSGP 2397



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 69/294 (23%), Positives = 111/294 (37%), Gaps = 62/294 (21%)

Query: 189 SWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYF 248
           +WFK+GA +P          S KV     GR L LG  Q+++  +    A          
Sbjct: 253 TWFKDGALLP---------TSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA---- 299

Query: 249 QVERGSRKWNYIYDKLSVHVTALTHMPTFSIPG------TLESGHPRNLTCSVPWACEQG 302
             E+ +R        L V+V      PT    G         +G P  L C       +G
Sbjct: 300 -AEKATR--------LDVYVP-----PTIEGAGGRPYVVKAVAGRPVALECVA-----RG 340

Query: 303 TP-PTITW----MGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357
            P PT++W    +  + S+     T  S+L L    +      +C  + P     +  +V
Sbjct: 341 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV 400

Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWG- 416
            + +  PPQ L   V +G G  +T +          GQ L L C    +P   + W    
Sbjct: 401 EVQV--PPQLL---VAEGLGQVTTIV----------GQPLELPCQASGSPVPTIQWLQNG 445

Query: 417 --SLTLSPSQSSNLG-VLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEY 467
             +  L+  Q ++ G  L +  V +   G F C+A N  G+    + +S+  E+
Sbjct: 446 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEW 499



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 6/81 (7%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEF 444
            + VL+GQ+ HL+C V  +P  +L+W      L+   + ++     +L++ + ++   G +
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232

Query: 445  TCRAQNPLG--SQHISLSLSL 463
            +C A N +G  ++H  LS+ L
Sbjct: 1233 SCIAANAVGEKTKHFQLSVLL 1253



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/217 (29%), Positives = 89/217 (41%), Gaps = 37/217 (17%)

Query: 279  IPGTLESGHPRNLTCSVPWA---CE-QGTP-PTITWM--GASVSSLDPTITRSSMLSLIP 331
            +P  +E+G P   T     A   C+ +G+P P ITW   G  VS  +   T      L+ 
Sbjct: 2754 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 2813

Query: 332  ---QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388
               + QD GT  TC  T   A     R V L I      L + VF       TTL    +
Sbjct: 2814 KNLEGQDAGT-YTC--TAENAVGRARRRVHLTI------LVLPVF-------TTLPGDRS 2857

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV--KDEGEFTC 446
            L +  G  L L CA   +P  R+ WT     ++   S   G   L R  V  +D G + C
Sbjct: 2858 LRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC 2915

Query: 447  RAQNPLGSQ------HISLSLSLQNE-YTGKMRPISG 476
             A+N +G        H+  +  LQ E ++  + P+ G
Sbjct: 2916 WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 2952



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 56/298 (18%)

Query: 180 WTASSPV-YGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 238
           WT+  P     W K+        PV    P  +VQED                 L I  +
Sbjct: 149 WTSGVPTPQVEWTKDRQ------PVLPGGPHLQVQEDGQ--------------VLRITGS 188

Query: 239 RKGDSGKYYFQVERGSRKWNYIYD-KLSVHVTALTHMPTFSIPGTLESGHPRNLTCS-VP 296
             GD G+Y  Q    S       D +L VH       PT  I G+ E+G    +    V 
Sbjct: 189 HVGDEGRY--QCVAFSPAGQQARDFQLRVHAP-----PT--IWGSNETGEVAVMEDHLVQ 239

Query: 297 WACE-QGTP-PTITWM--GASV-SSLDPTITRSSMLSLIPQPQDHGTSL-TCQVTLPGAG 350
             CE +G P P ITW   GA + +S     TR      + + Q     + TC+ +   A 
Sbjct: 240 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS--NAV 297

Query: 351 VTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPAR 410
               +A RL++  PP        +G G     ++       + G+ + L C    +P   
Sbjct: 298 GAAEKATRLDVYVPP------TIEGAGGRPYVVK------AVAGRPVALECVARGHPSPT 345

Query: 411 LSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
           LSW    L ++ S  S L     VL L        G ++C A +P G   +  S+ +Q
Sbjct: 346 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 403



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 80/380 (21%), Positives = 131/380 (34%), Gaps = 69/380 (18%)

Query: 120 VFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL----CVSVPCSVLY 175
           V  +E+  +     Y  ++ NV  S +L    R+ VP  +T+   L     V+ P  +  
Sbjct: 658 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 717

Query: 176 PHYNWTASSPVYGSWFKEGADI-PWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLS 234
              N T +      W K+G  + P   P     P G+V                    L+
Sbjct: 718 ---NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV--------------------LT 754

Query: 235 IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCS 294
           +  AR  DSG+Y         +     D+  V +    HMP   +   L      N + +
Sbjct: 755 LASARASDSGRYSCVAVSAVGE-----DRQDVVLQV--HMPPSILGEELNVSVVANESVA 807

Query: 295 VPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGV--- 351
           +        PP ++W                   L P+P  H ++    + +  A V   
Sbjct: 808 LECQSHAMPPPVLSWW-------------KDGRPLEPRPGVHLSADKALLQVDRADVWDA 854

Query: 352 ---TMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPP 408
              T     +   S    NL + V          LR    L+V EG    L C     P 
Sbjct: 855 GHYTCEALNQAGHSEKHYNLNVWV-----APVFPLRESHTLTVREGHPTRLSCECRGVPF 909

Query: 409 ARLSWTWGSLTLSPSQSSNLG-------VLELPRVHVKDEGEFTCRAQNPLG--SQHISL 459
            ++SW      L P + + L        +L L +  +  EG +TC   N +G  SQ + L
Sbjct: 910 PKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQL 968

Query: 460 SLSLQNEYTGKMRPISGVTL 479
            + +  +  G   P + V++
Sbjct: 969 EVHVPPQIAGPREPPTQVSV 988



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 43/188 (22%), Positives = 66/188 (35%), Gaps = 19/188 (10%)

Query: 286 GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLD--PTITRSSMLSLIPQPQDHGTSL 340
           G P  L C        G+P PTI W+  G     L      ++ + L +     DH    
Sbjct: 422 GQPLELPCQA-----SGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLF 476

Query: 341 TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 400
            CQ T           V ++  + P  L + +    G       + S+        +H  
Sbjct: 477 ACQATNEAGTAGAEVEVSVHGEWAPGVLEVPI----GQYHWGXEHHSSFPAACDPPVHRG 532

Query: 401 CAVDSNPPARLSWT-----WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455
                 PP    W      WG  T  P   S    L++ +V ++DEG +TC A N  G  
Sbjct: 533 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 592

Query: 456 HISLSLSL 463
              ++L +
Sbjct: 593 KREVALKV 600



 Score = 36.2 bits (82), Expect = 0.088
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWG----SLTLSPSQSSNLGVLELPRVHVKDEGEFT 445
           +VLE  S+ L C     PP  +SW  G    S  +  + S +  VL + +  + D G + 
Sbjct: 614 AVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 673

Query: 446 CRAQNPLGSQHISLSL 461
           C A N  GS  +   L
Sbjct: 674 CVASNVAGSTELRYGL 689



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 3/95 (3%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFT 445
            ++V  G  + L C     P   + W      L  S+       G L L  V   D G + 
Sbjct: 3036 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 3095

Query: 446  CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480
            C A N LGS      L ++ E  G    ++GV  G
Sbjct: 3096 CVAHNLLGSATARAFLVVRGEPQGSWGSMTGVING 3130



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444
            ++V    ++ L C    NP   +SW    L  SPS    +     VL++    V D   +
Sbjct: 1573 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASY 1632

Query: 445  TCRAQNPLGSQHISLSLSLQ 464
             C A+N  GS     +L +Q
Sbjct: 1633 MCVAENQAGSAEKLFTLRVQ 1652



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 389  LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444
            ++ +   S+ L C V ++P   ++W   S  LS  +   L      L+L R  + D G +
Sbjct: 1665 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMY 1724

Query: 445  TCRAQNPLGSQHISLSLSL 463
            TC A N  G     + LS+
Sbjct: 1725 TCEALNAAGRDQKLVQLSV 1743



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%)

Query: 378 TASTTLRNGSALSVL--EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS----QSSNLG-V 430
           T  + L  G+A  VL   G  + L C     P  ++ WT     + P     Q    G V
Sbjct: 123 TPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV 182

Query: 431 LELPRVHVKDEGEFTCRAQNPLGSQ 455
           L +   HV DEG + C A +P G Q
Sbjct: 183 LRITGSHVGDEGRYQCVAFSPAGQQ 207



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 43/185 (23%), Positives = 67/185 (36%), Gaps = 30/185 (16%)

Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360
           +G  P  +WMG +VS +D  + R     L     D G S  C  +       +   +R+N
Sbjct: 639 KGHQPVSSWMGVTVS-VDGRVLRIEQAQL----SDAG-SYRCVASNVAGSTELRYGLRVN 692

Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420
           +  PP+               TL       VL    + L C     P   L W      +
Sbjct: 693 V--PPR--------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPV 736

Query: 421 SPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLGS--QHISLSLSLQNEYTGKMR 472
           SP+ +  L       VL L      D G ++C A + +G   Q + L + +     G+  
Sbjct: 737 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEEL 796

Query: 473 PISGV 477
            +S V
Sbjct: 797 NVSVV 801



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 369  TMTVFQGDGTASTTLRNGS-ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---- 423
            T   F+ +     T+R+G  A++V   Q+  L C  D  P   +SW    + L P     
Sbjct: 2379 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2438

Query: 424  QSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
            +    G L +  V  +D G + C A N  GS
Sbjct: 2439 EILPEGSLRIQPVLAQDAGHYLCLASNSAGS 2469



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%)

Query: 397  LHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPL 452
            L L+C     PP  + W  G   +SP + + L     +L++ +   +D G ++C A N  
Sbjct: 1088 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1147

Query: 453  GSQHISLSL------SLQNE 466
            G    + S+      S++NE
Sbjct: 1148 GEARRNFSVEVLVPPSIENE 1167



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 386  GSALSVLE---GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVK 439
            G A S L    G S+ L C V  +P   + W    L L  S   +    G L + R    
Sbjct: 2940 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERD 2999

Query: 440  DEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRP 473
            D G + C A+N +G     + L LQ+    ++ P
Sbjct: 3000 DAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 3033



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 29/90 (32%)

Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWT--------------------WGSL----TLSPSQ 424
           +S + GQSL L C  +  P   + W                     WG +     L   Q
Sbjct: 28  VSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ 87

Query: 425 SSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454
           S     L  PR+   D G ++CRA+N  G+
Sbjct: 88  S-----LHFPRIQEGDSGLYSCRAENQAGT 112



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 4/81 (4%)

Query: 388  ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGE 443
            A+ V  G    L C  D+ P   ++W      L  +Q +        LE+    V D+G 
Sbjct: 1759 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 1818

Query: 444  FTCRAQNPLGSQHISLSLSLQ 464
            ++C+  N  G    + +L++Q
Sbjct: 1819 YSCKVSNVAGEAVRTFTLTVQ 1839


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 54/228 (23%), Positives = 93/228 (40%), Gaps = 35/228 (15%)

Query: 230 NCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM-PTFSIPG-TLESGH 287
           N SL I++  + D+G Y  QV +         D ++   T   H+ P    P  +  + +
Sbjct: 104 NASLLIQNVTQNDTGFYTLQVIKS--------DLVNEEATGQFHVYPELPKPSISSNNSN 155

Query: 288 PRNLTCSVPWACEQGTPPT--ITWMGASVSSLDPTITRSS---MLSLIPQPQDHGTSLTC 342
           P     +V + CE     T  + W+      + P +  S+    L+L+   ++   S  C
Sbjct: 156 PVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYEC 215

Query: 343 QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402
           ++  P A    +  V LN+ Y P   T++               S  +   G++L+L C 
Sbjct: 216 EIQNP-ASANRSDPVTLNVLYGPDGPTISP--------------SKANYRPGENLNLSCH 260

Query: 403 VDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450
             SNPPA+ SW         +Q      L +P + V + G + C+A N
Sbjct: 261 AASNPPAQYSWFINGTFQQSTQE-----LFIPNITVNNSGSYMCQAHN 303


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 85/317 (26%), Positives = 129/317 (40%), Gaps = 43/317 (13%)

Query: 158 SVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTH 217
           SVTV+E  C S   +         + + VY +   EG   P +I    N  S  +++DT 
Sbjct: 223 SVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKP-EIIWIHNNHSLDLEDDTR 281

Query: 218 GRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTF 277
              L + D  T    L IR+ R+ D G Y       + +         +  ++L   P+F
Sbjct: 282 ---LNVFDDGT----LMIRNTRESDQGVYQCMARNSAGEAKT--QSAMLRYSSLPAKPSF 332

Query: 278 SI-PGTLES--GHPRNLTCSVPWACEQGTP-PTITWMGASVSSLDPT--ITRSSMLSLIP 331
            I P   E   G    L C        G P P ITW   +   LD +  +  SS L L  
Sbjct: 333 VIQPQDTEVLIGTSTTLECMAT-----GHPHPLITWTRDNGLELDGSRHVATSSGLYLQN 387

Query: 332 QPQ-DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390
             Q DHG   TC      +  T+  A  + +  PPQ    TV   D              
Sbjct: 388 ITQRDHGR-FTCHAN--NSHGTVQAAANIIVQAPPQ---FTVTPKDQV------------ 429

Query: 391 VLEGQSLHLVCAVDSNPPARLSWT--WGSLTLSPSQSS-NLGVLELPRVHVKDEGEFTCR 447
           VLE  ++  +C  D NPP  + WT   G L +    +  + G L + R    D+G++ C+
Sbjct: 430 VLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQ 489

Query: 448 AQNPLGSQHISLSLSLQ 464
           A + LG + +S+ L+++
Sbjct: 490 AVSSLGVKKVSVQLTVK 506



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 93/444 (20%), Positives = 154/444 (34%), Gaps = 100/444 (22%)

Query: 31  SVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQEETR 90
           SVTV+E  C S   +F  PQ+    S     +  RA  +    I    NN +  ++++TR
Sbjct: 223 SVTVEEFNCQSPRITFE-PQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTR 281

Query: 91  DRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSR 150
                       D TL IR+TRESD G Y  C+ R            S     +Q  + R
Sbjct: 282 LNVF-------DDGTLMIRNTRESDQGVYQ-CMARN-----------SAGEAKTQSAMLR 322

Query: 151 YR--------LEVPESVTVQEGLCVSVPCSVL---YPHYNWTASSPVYGSWFKEGADIPW 199
           Y         +  P+   V  G   ++ C      +P   WT  +         G ++  
Sbjct: 323 YSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDN---------GLELDG 373

Query: 200 DIPVATNTP--SGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKW 257
              VAT++      + +  HGRF        NN   +++ A                   
Sbjct: 374 SRHVATSSGLYLQNITQRDHGRFTC----HANNSHGTVQAA------------------- 410

Query: 258 NYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQ--GTPPTITWM---GA 312
                  ++ V A            +   H      +V W CE     PP I W    G 
Sbjct: 411 ------ANIIVQAPPQFTVTPKDQVVLEEH------AVEWLCEADGNPPPVIVWTKTGGQ 458

Query: 313 SVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTV 372
                  T+  S  L +    Q       CQ  +   GV   + V + ++  P+ L +  
Sbjct: 459 LPVEGQHTVLSSGTLRIDRAAQHDQGQYECQ-AVSSLGV---KKVSVQLTVKPKALAV-- 512

Query: 373 FQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---G 429
                   T L   +++ V  G+++++ C     P   ++W    + ++ S   ++   G
Sbjct: 513 -------FTQLPQDTSVEV--GKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEG 563

Query: 430 VLELPRVHVKDEGEFTCRAQNPLG 453
            L +      D+G + C A+N  G
Sbjct: 564 TLTIYDAGFPDQGRYECVARNSFG 587


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,586,351
Number of Sequences: 37866
Number of extensions: 1268003
Number of successful extensions: 6496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 4734
Number of HSP's gapped (non-prelim): 1530
length of query: 595
length of database: 18,247,518
effective HSP length: 108
effective length of query: 487
effective length of database: 14,157,990
effective search space: 6894941130
effective search space used: 6894941130
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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