BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|16506828 sialic acid binding immunoglobulin-like lectin-like protein 1 isoform a precursor [Homo sapiens] (595 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 1224 0.0 gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 931 0.0 gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ... 629 e-180 gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 627 e-180 gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] 597 e-171 gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec... 418 e-117 gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec... 390 e-108 gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec... 364 e-100 gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom... 354 1e-97 gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] 332 8e-91 gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] 311 1e-84 gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 288 1e-77 gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] 287 2e-77 gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 272 6e-73 gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 239 7e-63 gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] 149 7e-36 gi|11225258 myelin associated glycoprotein isoform a precursor [... 118 1e-26 gi|18104957 myelin associated glycoprotein isoform b precursor [... 118 1e-26 gi|13489095 sialoadhesin precursor [Homo sapiens] 96 1e-19 gi|157168355 CD22 molecule [Homo sapiens] 86 1e-16 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 59 1e-08 gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 57 4e-08 gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 57 6e-08 gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 57 6e-08 gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens] 56 1e-07 gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 55 2e-07 gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 55 2e-07 gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 55 2e-07 gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 54 3e-07 gi|126517478 peroxidasin homolog-like [Homo sapiens] 54 3e-07 >gi|16506828 sialic acid binding immunoglobulin-like lectin-like protein 1 isoform a precursor [Homo sapiens] Length = 595 Score = 1224 bits (3167), Expect = 0.0 Identities = 595/595 (100%), Positives = 595/595 (100%) Query: 1 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH Sbjct: 1 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60 Query: 61 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV Sbjct: 61 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120 Query: 121 FCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNW 180 FCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNW Sbjct: 121 FCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNW 180 Query: 181 TASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARK 240 TASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARK Sbjct: 181 TASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARK 240 Query: 241 GDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACE 300 GDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACE Sbjct: 241 GDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACE 300 Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN Sbjct: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360 Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL Sbjct: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420 Query: 421 SPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480 SPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG Sbjct: 421 SPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480 Query: 481 AFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESP 540 AFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESP Sbjct: 481 AFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESP 540 Query: 541 ADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 595 ADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK Sbjct: 541 ADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 595 >gi|16506826 sialic acid binding immunoglobulin-like lectin-like protein 1 isoform b precursor [Homo sapiens] Length = 477 Score = 931 bits (2407), Expect = 0.0 Identities = 454/454 (100%), Positives = 454/454 (100%) Query: 142 TASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDI 201 TASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDI Sbjct: 24 TASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDI 83 Query: 202 PVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY 261 PVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY Sbjct: 84 PVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY 143 Query: 262 DKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTI 321 DKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTI Sbjct: 144 DKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTI 203 Query: 322 TRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAST 381 TRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAST Sbjct: 204 TRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAST 263 Query: 382 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDE 441 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDE Sbjct: 264 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDE 323 Query: 442 GEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVV 501 GEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVV Sbjct: 324 GEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVV 383 Query: 502 VRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEG 561 VRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEG Sbjct: 384 VRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEG 443 Query: 562 EIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 595 EIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK Sbjct: 444 EIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 477 Score = 161 bits (408), Expect = 1e-39 Identities = 129/370 (34%), Positives = 183/370 (49%), Gaps = 44/370 (11%) Query: 24 YLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPAR 83 Y L + +SVTVQEGLCVSV CS YP WTAS PV+G WF+ G + +IPVATN P+ Sbjct: 33 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 92 Query: 84 AVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTA 143 VQE+T RF LLGDPQ +C+LSIRD R+ D+G Y F VERG+ KWNY YD+LSV+VTA Sbjct: 93 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 152 Query: 144 SQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV 203 L +P T++ G ++ CSV + T P +W GA + P Sbjct: 153 ---LTHMPTFSIPG--TLESGHPRNLTCSVPWACEQGT---PPTITWM--GASVSSLDPT 202 Query: 204 ATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDK 263 T + L+ PQ + SL+ + G +G + R +Y Sbjct: 203 ITRS----------SMLSLIPQPQDHGTSLTCQVTLPG-AGVTMTRAVR--LNISYPPQN 249 Query: 264 LSVHV-----TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLD 318 L++ V TA T + S LE G +L C+V + P ++W S+ +L Sbjct: 250 LTMTVFQGDGTASTTLRNGSALSVLE-GQSLHLVCAV----DSNPPARLSWTWGSL-TLS 303 Query: 319 PTITRSSMLSLIPQPQDH---GTSLTCQVTLPGAGVTMTRAVRLNISY-----PPQNLTM 370 P ++SS L ++ P+ H TC+ P ++ ++ L Y P +T+ Sbjct: 304 P--SQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTL 361 Query: 371 TVFQGDGTAS 380 F G G + Sbjct: 362 GAFGGAGATA 371 >gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo sapiens] Length = 467 Score = 629 bits (1622), Expect = e-180 Identities = 318/445 (71%), Positives = 356/445 (80%), Gaps = 3/445 (0%) Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210 Y L + SVTVQEG+CV V CS YP + T S PV+G WF+ G DI W PVATN P+ Sbjct: 26 YSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAW 85 Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 270 VQE+T RF LLGDPQT NC+LSIRDAR D+G+Y+F++E+G+ KWNY YD+LSV+VTA Sbjct: 86 AVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTA 145 Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330 LTH P IPGTLESG +NLTCSVPWACEQGTPP I+WMG SVS L P+ TRSS+L+LI Sbjct: 146 LTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLI 205 Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390 PQPQ HGTSLTCQVTLPGAGVT R ++LN+SYPPQNLT+TVFQG+GTAST L N S+LS Sbjct: 206 PQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLS 265 Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450 VLEGQSL LVCAVDSNPPARLSWTW SLTL PSQ SN VLEL +VH+ DEGEFTCRAQN Sbjct: 266 VLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQN 324 Query: 451 PLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA 510 LGSQH+SL+LSLQ EYTGKMRP+SGV LGA GGAGATALVFL FC+IF+VVRSCRKKSA Sbjct: 325 SLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSA 384 Query: 511 RPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSF 570 RPA VGD GM+DAN +RGSASQG L ES ADD+P HH A S EE EIQYA LSF Sbjct: 385 RPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHSSGEEREIQYAPLSF 442 Query: 571 HKARPQYPQEQEAIGYEYSEINIPK 595 HK PQ QEA EYSEI IPK Sbjct: 443 HKGEPQDLSGQEATNNEYSEIKIPK 467 Score = 216 bits (549), Expect = 6e-56 Identities = 120/200 (60%), Positives = 141/200 (70%), Gaps = 18/200 (9%) Query: 3 LLLLLLPPLLCGRVGAKEQK----DYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDP 58 +LLLLL PLL GR + QK DY LTMQ SVTVQEG+CV V CSFSYP + T SDP Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 Query: 59 VHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGT 118 VHGYWFRAG+ +S PVATNNPA AVQEETRDRFHLLGDPQ K+CTLSIRD R SDAG Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 Query: 119 YVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY--- 175 Y F +E+GN+KWNYKYDQLSVNVTA L R + +P T++ G ++ CSV + Sbjct: 121 YFFRMEKGNIKWNYKYDQLSVNVTA---LTHRPNILIPG--TLESGCFQNLTCSVPWACE 175 Query: 176 ----PHYNW--TASSPVYGS 189 P +W T+ SP++ S Sbjct: 176 QGTPPMISWMGTSVSPLHPS 195 >gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] Length = 499 Score = 627 bits (1618), Expect = e-180 Identities = 321/451 (71%), Positives = 354/451 (78%), Gaps = 6/451 (1%) Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210 Y L+V E VTVQEGLCV VPCS YP WT S PV+G WF+ G D PVATN P Sbjct: 27 YLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDR 86 Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKW------NYIYDKL 264 +VQ +T GRF LLGD +N+CSLSIRDARK D G Y+F++ERGS KW NY +L Sbjct: 87 EVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQL 146 Query: 265 SVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRS 324 SV VTALTH P I GTLESGH RNLTCSVPWAC+QGTPP I+W+GASVSS PT RS Sbjct: 147 SVFVTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARS 206 Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384 S+L+L P+PQDHGTSLTCQVTLPG GVT T VRL++SYPP NLTMTVFQGD TAST L Sbjct: 207 SVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALG 266 Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444 NGS+LSVLEGQSL LVCAV+SNPPARLSWT GSLTL PS+SSN G+LELPRVHV+DEGEF Sbjct: 267 NGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEF 326 Query: 445 TCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRS 504 TCRAQN GSQHISLSLSLQNE TG RP+S VTL A GGAGATAL FL FCIIF++VRS Sbjct: 327 TCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRS 386 Query: 505 CRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQ 564 CRKKSARPA GVGDTGMEDA A+RGSASQGPL ES D +P PPA+A S EEGE+ Sbjct: 387 CRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPSSGEEGELH 446 Query: 565 YASLSFHKARPQYPQEQEAIGYEYSEINIPK 595 YA+LSFHK +PQ PQ QEA EYSEI I K Sbjct: 447 YATLSFHKVKPQDPQGQEATDSEYSEIKIHK 477 Score = 185 bits (469), Expect = 1e-46 Identities = 133/345 (38%), Positives = 176/345 (51%), Gaps = 36/345 (10%) Query: 2 LLLLLLLPPLLCGRVGAKEQKDY----LLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASD 57 +LLLLLL PLL G G + + Y LL +Q+ VTVQEGLCV V CSFSYPQ+GWT SD Sbjct: 1 MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSD 60 Query: 58 PVHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAG 117 PVHGYWFRAGD ++ PVATNNP R VQ ET+ RF LLGD + DC+LSIRD R+ D G Sbjct: 61 PVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKG 120 Query: 118 TYVFCVERGNMKW------NYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPC 171 +Y F +ERG+MKW NYK QLSV VTA +R ++ T++ G ++ C Sbjct: 121 SYFFRLERGSMKWSYKSQLNYKTKQLSVFVTA-----LTHRPDILILGTLESGHSRNLTC 175 Query: 172 SVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNC 231 SV + T P SW P ++ + + HG L C Sbjct: 176 SVPWACKQGT---PPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSL--------TC 224 Query: 232 SLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNL 291 +++ G + +++ WN TA T + S LE G L Sbjct: 225 QVTLPGT--GVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLE-GQSLRL 281 Query: 292 TCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDH 336 C+V P ++W S+ +L P +RSS L+ P+ H Sbjct: 282 VCAV----NSNPPARLSWTRGSL-TLCP--SRSSNPGLLELPRVH 319 >gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] Length = 463 Score = 597 bits (1540), Expect = e-171 Identities = 304/445 (68%), Positives = 346/445 (77%), Gaps = 10/445 (2%) Query: 153 LEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPV-YGSWFKEGADIPWDIPVATNTPSGK 211 L + SVTVQEGLCV VPCS YP + W PV +G WF+EGA+ D PVATN P+ Sbjct: 23 LTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGYWFREGANTDQDAPVATNNPARA 82 Query: 212 VQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTAL 271 V E+T RF LLGDP T NC+LSIRDAR+ D+G+Y+F++E+GS KWNY + +LSV+VTAL Sbjct: 83 VWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKWNYKHHRLSVNVTAL 142 Query: 272 THMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP 331 TH P IPGTLESG P+NLTCSVPWACEQGTPP I+W+G SVS LDP+ TRSS+L+LIP Sbjct: 143 THRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWIGTSVSPLDPSTTRSSVLTLIP 202 Query: 332 QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSV 391 QPQDHGTSLTCQVT PGA VT + V LN+SYPPQNLTMTVFQGDGT ST L NGS+LS+ Sbjct: 203 QPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSL 262 Query: 392 LEGQSLHLVC---AVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRA 448 EGQSL LVC AVDSNPPARLS +W LTL PSQ SN GVLELP VH++D EFTCRA Sbjct: 263 PEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRA 322 Query: 449 QNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKK 508 QNPLGSQ + L++SLQ++ T SGVT G GGAGATALVFL FC+IFVVVRSCRKK Sbjct: 323 QNPLGSQQVYLNVSLQSKAT------SGVTQGVVGGAGATALVFLSFCVIFVVVRSCRKK 376 Query: 509 SARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASL 568 SARPA GVGDTG+EDANAVRGSASQGPL E A+DSPP PPA A S EGE+QYASL Sbjct: 377 SARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARSSVGEGELQYASL 436 Query: 569 SFHKARPQYPQEQEAIGYEYSEINI 593 SF +P + QEA EYSEI I Sbjct: 437 SFQMVKPWDSRGQEATDTEYSEIKI 461 Score = 199 bits (506), Expect = 6e-51 Identities = 108/189 (57%), Positives = 130/189 (68%), Gaps = 13/189 (6%) Query: 4 LLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPV-HGY 62 +LLLL PLL GR A+ Q LLTMQ SVTVQEGLCV V CSFSYP +GW PV HGY Sbjct: 1 MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGY 60 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 WFR G + ++ PVATNNPARAV EETRDRFHLLGDP K+CTLSIRD R SDAG Y F Sbjct: 61 WFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFR 120 Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175 +E+G++KWNYK+ +LSVNVTA L R + +P T++ G ++ CSV + Sbjct: 121 MEKGSIKWNYKHHRLSVNVTA---LTHRPNILIPG--TLESGCPQNLTCSVPWACEQGTP 175 Query: 176 PHYNWTASS 184 P +W +S Sbjct: 176 PMISWIGTS 184 >gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 precursor [Homo sapiens] Length = 453 Score = 418 bits (1074), Expect = e-117 Identities = 234/447 (52%), Positives = 292/447 (65%), Gaps = 24/447 (5%) Query: 150 RYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPS 209 R++LE PES+TVQEGLCV VPC + AS YG WF EGAD+P VATN P Sbjct: 30 RFQLEGPESLTVQEGLCVLVPCRL---PTTLPASYYGYGYWFLEGADVP----VATNDPD 82 Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVT 269 +VQE+T GRF LL DP+ NCSLSIRDAR+ D+ Y+F+++ K+ Y KLSV V Sbjct: 83 EEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVM 142 Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSL 329 ALTH P SIPGTLESGHP NLTCSVPW CEQGTPP +WM A+ +SL P T+SS+L++ Sbjct: 143 ALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTI 202 Query: 330 IPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389 P+PQDH T+LTCQVT PGAGVTM R ++LN+SY PQ + +++FQG+ A L+N S+L Sbjct: 203 TPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSL 262 Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449 VLEGQ+L L+C D NPPA LSW G L+ + SN GVLELP+V +EG+FTCRAQ Sbjct: 263 PVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQ 322 Query: 450 NPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKS 509 +PLGS ISLSL + + G+ +G LGA GA T LVFL C IF V++ RKK+ Sbjct: 323 HPLGSLQISLSLFVHWKPEGR----AGGVLGAVWGASITTLVFLCVCFIF-RVKTRRKKA 377 Query: 510 ARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATP-SPEEGEIQYASL 568 A+P +D N V S S+G + H PA A P S +E E+ YA L Sbjct: 378 AQPV-----QNTDDVNPVMVSGSRGHQHQFQTGIVSDH---PAEAGPISEDEQELHYAVL 429 Query: 569 SFHKARPQYPQEQEAIGYEYSEINIPK 595 FHK +PQ P+ + EYSEI I K Sbjct: 430 HFHKVQPQEPKVTDT---EYSEIKIHK 453 Score = 112 bits (280), Expect = 1e-24 Identities = 75/190 (39%), Positives = 106/190 (55%), Gaps = 21/190 (11%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 +L LLLP L G + +++ + L +S+TVQEGLCV V C AS +GY Sbjct: 12 MLPLLLPLLWAGALA--QERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGY 66 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 WF G ++PVATN+P VQEETR RFHLL DP+ K+C+LSIRD R D Y F Sbjct: 67 WFLEG----ADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122 Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175 ++ MK+ Y +LSV V A L R + +P T++ G ++ CSV + Sbjct: 123 LKSKWMKYGYTSSKLSVRVMA---LTHRPNISIPG--TLESGHPSNLTCSVPWVCEQGTP 177 Query: 176 PHYNWTASSP 185 P ++W +++P Sbjct: 178 PIFSWMSAAP 187 >gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 precursor [Homo sapiens] Length = 437 Score = 390 bits (1002), Expect = e-108 Identities = 227/447 (50%), Positives = 281/447 (62%), Gaps = 40/447 (8%) Query: 150 RYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPS 209 R++LE PES+TVQEGLCV VPC + AS YG WF EGAD+P VATN P Sbjct: 30 RFQLEGPESLTVQEGLCVLVPCRL---PTTLPASYYGYGYWFLEGADVP----VATNDPD 82 Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVT 269 +VQE+T GRF LL DP+ NCSLSIRDAR+ D+ Y+F+++ K+ Y KLSV V Sbjct: 83 EEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVM 142 Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSL 329 ALTH P SIPGTLESGHP NLTCSVPW CEQGTPP +WM A+ +SL P T+SS+L++ Sbjct: 143 ALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTI 202 Query: 330 IPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389 P+PQDH T+LTCQVT PGAGVTM R ++LN+S + L+N S+L Sbjct: 203 TPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVS----------------SFKILQNTSSL 246 Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449 VLEGQ+L L+C D NPPA LSW G L+ + SN GVLELP+V +EG+FTCRAQ Sbjct: 247 PVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQ 306 Query: 450 NPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKS 509 +PLGS ISLSL + + G+ +G LGA GA T LVFL C IF V++ RKK+ Sbjct: 307 HPLGSLQISLSLFVHWKPEGR----AGGVLGAVWGASITTLVFLCVCFIF-RVKTRRKKA 361 Query: 510 ARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATP-SPEEGEIQYASL 568 A+P +D N V S S+G + H PA A P S +E E+ YA L Sbjct: 362 AQPV-----QNTDDVNPVMVSGSRGHQHQFQTGIVSDH---PAEAGPISEDEQELHYAVL 413 Query: 569 SFHKARPQYPQEQEAIGYEYSEINIPK 595 FHK +PQ P+ + EYSEI I K Sbjct: 414 HFHKVQPQEPKVTDT---EYSEIKIHK 437 Score = 112 bits (280), Expect = 1e-24 Identities = 75/190 (39%), Positives = 106/190 (55%), Gaps = 21/190 (11%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 +L LLLP L G + +++ + L +S+TVQEGLCV V C AS +GY Sbjct: 12 MLPLLLPLLWAGALA--QERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGY 66 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 WF G ++PVATN+P VQEETR RFHLL DP+ K+C+LSIRD R D Y F Sbjct: 67 WFLEG----ADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122 Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175 ++ MK+ Y +LSV V A L R + +P T++ G ++ CSV + Sbjct: 123 LKSKWMKYGYTSSKLSVRVMA---LTHRPNISIPG--TLESGHPSNLTCSVPWVCEQGTP 177 Query: 176 PHYNWTASSP 185 P ++W +++P Sbjct: 178 PIFSWMSAAP 187 >gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 precursor [Homo sapiens] Length = 353 Score = 364 bits (934), Expect = e-100 Identities = 183/312 (58%), Positives = 225/312 (72%), Gaps = 7/312 (2%) Query: 150 RYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPS 209 R++LE PES+TVQEGLCV VPC + AS YG WF EGAD+P VATN P Sbjct: 30 RFQLEGPESLTVQEGLCVLVPCRL---PTTLPASYYGYGYWFLEGADVP----VATNDPD 82 Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVT 269 +VQE+T GRF LL DP+ NCSLSIRDAR+ D+ Y+F+++ K+ Y KLSV V Sbjct: 83 EEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVM 142 Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSL 329 ALTH P SIPGTLESGHP NLTCSVPW CEQGTPP +WM A+ +SL P T+SS+L++ Sbjct: 143 ALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTI 202 Query: 330 IPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389 P+PQDH T+LTCQVT PGAGVTM R ++LN+SY PQ + +++FQG+ A L+N S+L Sbjct: 203 TPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSL 262 Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449 VLEGQ+L L+C D NPPA LSW G L+ + SN GVLELP+V +EG+FTCRAQ Sbjct: 263 PVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQ 322 Query: 450 NPLGSQHISLSL 461 +PLGS ISLSL Sbjct: 323 HPLGSLQISLSL 334 Score = 112 bits (280), Expect = 1e-24 Identities = 75/190 (39%), Positives = 106/190 (55%), Gaps = 21/190 (11%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 +L LLLP L G + +++ + L +S+TVQEGLCV V C AS +GY Sbjct: 12 MLPLLLPLLWAGALA--QERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGY 66 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 WF G ++PVATN+P VQEETR RFHLL DP+ K+C+LSIRD R D Y F Sbjct: 67 WFLEG----ADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122 Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------- 175 ++ MK+ Y +LSV V A L R + +P T++ G ++ CSV + Sbjct: 123 LKSKWMKYGYTSSKLSVRVMA---LTHRPNISIPG--TLESGHPSNLTCSVPWVCEQGTP 177 Query: 176 PHYNWTASSP 185 P ++W +++P Sbjct: 178 PIFSWMSAAP 187 >gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo sapiens] Length = 374 Score = 354 bits (908), Expect = 1e-97 Identities = 220/445 (49%), Positives = 256/445 (57%), Gaps = 96/445 (21%) Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210 Y L + SVTVQEG+CV V CS YP + T S PV+G WF+ G DI W PVATN P+ Sbjct: 26 YSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAW 85 Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 270 VQE+T RF LLGDPQT NC+LSIRDAR D+G+Y+F++E+G+ KWNY YD+LSV+VT Sbjct: 86 AVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVT- 144 Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330 P+NLT +V QG T +G SS LS++ Sbjct: 145 ---------------DPPQNLTVTV----FQGEGTASTALG-----------NSSSLSVL 174 Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390 + L C V S PP L+ T Sbjct: 175 ---EGQSLRLVCAVD----------------SNPPARLSWT------------------- 196 Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450 +SL L + SNP VLEL +VH+ DEGEFTCRAQN Sbjct: 197 ---WRSLTLYPSQPSNPL---------------------VLEL-QVHLGDEGEFTCRAQN 231 Query: 451 PLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA 510 LGSQH+SL+LSLQ EYTGKMRP+SGV LGA GGAGATALVFL FC+IF+VVRSCRKKSA Sbjct: 232 SLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSA 291 Query: 511 RPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSF 570 RPA VGD GM+DAN +RGSASQG L ES ADD+P HH A S EE EIQYA LSF Sbjct: 292 RPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHSSGEEREIQYAPLSF 349 Query: 571 HKARPQYPQEQEAIGYEYSEINIPK 595 HK PQ QEA EYSEI IPK Sbjct: 350 HKGEPQDLSGQEATNNEYSEIKIPK 374 Score = 208 bits (530), Expect = 1e-53 Identities = 105/144 (72%), Positives = 115/144 (79%), Gaps = 4/144 (2%) Query: 3 LLLLLLPPLLCGRVGAKEQK----DYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDP 58 +LLLLL PLL GR + QK DY LTMQ SVTVQEG+CV V CSFSYP + T SDP Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 Query: 59 VHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGT 118 VHGYWFRAG+ +S PVATNNPA AVQEETRDRFHLLGDPQ K+CTLSIRD R SDAG Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 Query: 119 YVFCVERGNMKWNYKYDQLSVNVT 142 Y F +E+GN+KWNYKYDQLSVNVT Sbjct: 121 YFFRMEKGNIKWNYKYDQLSVNVT 144 >gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] Length = 396 Score = 332 bits (850), Expect = 8e-91 Identities = 172/318 (54%), Positives = 218/318 (68%), Gaps = 5/318 (1%) Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV-ATNTPS 209 Y L+V +SVTVQEGLCV VPCS YP +W +S P+Y WF++G +IP+ V ATN P Sbjct: 21 YELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDG-EIPYYAEVVATNNPD 79 Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHV 268 +V+ +T GRF LLGD Q NCSLSI DAR D+G Y+F+VERG K++Y +KL++ V Sbjct: 80 RRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEV 139 Query: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLS 328 TAL P LESG P L+CS+P +CE G P T +W G ++S LDP TRSS L+ Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELT 199 Query: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF--QGDGTASTTLRNG 386 L P+P+DHGT+LTCQV GA VT R V+LN+SY PQNL +++F G GTA L NG Sbjct: 200 LTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNG 259 Query: 387 SALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTC 446 ++ + EGQSL L C VDSNPPA LSW L+PSQ+S G LELP + ++ GEFTC Sbjct: 260 MSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTC 319 Query: 447 RAQNPLGSQHISLSLSLQ 464 R Q+PLGSQH+S LS+Q Sbjct: 320 RVQHPLGSQHLSFILSVQ 337 Score = 137 bits (346), Expect = 2e-32 Identities = 80/157 (50%), Positives = 104/157 (66%), Gaps = 2/157 (1%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 +L LLL PLL G +E+ Y L +QKSVTVQEGLCV V CSFSYP W +S P++ Y Sbjct: 1 MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 WFR G+ VATNNP R V+ ET+ RF LLGD Q K+C+LSI D R D G+Y F Sbjct: 60 WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119 Query: 123 VERG-NMKWNYKYDQLSVNVTASQDLLSRYRLEVPES 158 VERG ++K++Y+ ++L++ VTA + + LE ES Sbjct: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES 156 >gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] Length = 551 Score = 311 bits (797), Expect = 1e-84 Identities = 168/315 (53%), Positives = 215/315 (68%), Gaps = 6/315 (1%) Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV-ATNTPS 209 Y L+V +SVTVQEGLCV VPCS YP +W +S P+Y WF++G +IP+ V ATN P Sbjct: 21 YELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDG-EIPYYAEVVATNNPD 79 Query: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHV 268 +V+ +T GRF LLGD Q NCSLSI DAR D+G Y+F+VERG K++Y +KL++ V Sbjct: 80 RRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEV 139 Query: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLS 328 TAL P LESG P L+CS+P +CE G P T +W G ++S LDP TRSS L+ Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELT 199 Query: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388 L P+P+DHGT+LTCQ+ GA VT R V+LN+SY PQ T+T+F+ +G A L+N S Sbjct: 200 LTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQ--TITIFR-NGIALEILQNTSY 256 Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRA 448 L VLEGQ+L L+C SNPPA LSW GS L+ + SN G+LEL RV +EG FTCRA Sbjct: 257 LPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRA 316 Query: 449 QNPLGSQHISLSLSL 463 Q+PLG I L+LS+ Sbjct: 317 QHPLGFLQIFLNLSV 331 Score = 194 bits (492), Expect = 3e-49 Identities = 194/615 (31%), Positives = 283/615 (46%), Gaps = 86/615 (13%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 +L LLL PLL G +E+ Y L +QKSVTVQEGLCV V CSFSYP W +S P++ Y Sbjct: 1 MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 WFR G+ VATNNP R V+ ET+ RF LLGD Q K+C+LSI D R D G+Y F Sbjct: 60 WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119 Query: 123 VERG-NMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWT 181 VERG ++K++Y+ ++L++ VTA + + LE ES G + CS+ + Sbjct: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES-----GRPTRLSCSL---PGSCE 171 Query: 182 ASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKG 241 A P+ SW A P D P T + L P+ + +L+ + R+G Sbjct: 172 AGPPLTFSW-TGNALSPLD-PETTRS----------SELTLTPRPEDHGTNLTCQMKRQG 219 Query: 242 DSGKYYFQVERGSRKWNYIYDKLSVHV----TALTHMPTFSIPGTLESGHPRNLTCSVPW 297 ER + + N Y ++ + AL + S LE G L C P Sbjct: 220 AQ----VTTER-TVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLE-GQALRLLCDAP- 272 Query: 298 ACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357 P ++W S + I+ + +L L TC+ P + + + Sbjct: 273 ---SNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQI--FL 327 Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSW---- 413 L++ PQ L G + S E + LH C+ + P L W Sbjct: 328 NLSVYSLPQLL-----------------GPSCS-WEAEGLHCRCSFRARPAPSLCWRLEE 369 Query: 414 -------TWGSLTLSPSQSSNLGVLELPRVH--VKDEGEFTCRAQNPLGSQHISLSLSLQ 464 + GS ++ S + L +H + + + +C+A N GSQ S+ L Sbjct: 370 KPLEGNSSQGSFKVNSSSAGPWANSSL-ILHGGLSSDLKVSCKAWNIYGSQSGSVLL--- 425 Query: 465 NEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA--RPAVGVGDTGME 522 G+ +GV A GGAG AL+ + C+IF ++ R+K A RP M+ Sbjct: 426 --LQGRSNLGTGVVPAALGGAGVMALLCICLCLIFFLIVKARRKQAAGRP------EKMD 477 Query: 523 DANAVRGSASQGPLIESPADDSPPHHA-PPALATPSPEEGEIQYASLSFHKARPQYPQEQ 581 D + + G+ + G + P DSP A PP A P E+ E+ YASLSF + + + P++Q Sbjct: 478 DEDPIMGTITSGSR-KKPWPDSPGDQASPPGDAPPLEEQKELHYASLSFSEMKSREPKDQ 536 Query: 582 EAIG-YEYSEINIPK 595 EA EYSEI K Sbjct: 537 EAPSTTEYSEIKTSK 551 >gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo sapiens] Length = 602 Score = 288 bits (736), Expect = 1e-77 Identities = 219/603 (36%), Positives = 304/603 (50%), Gaps = 48/603 (7%) Query: 1 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60 MLLL LLLP L G + + Y L +Q+ V V EGLCV V C+ SYP++GW S + Sbjct: 13 MLLLPLLLPVLGAGSLN--KDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAY 70 Query: 61 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120 GYWF+ PVATNN +R V+ TRDRF L GDP C+L IRD + D Y Sbjct: 71 GYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYF 130 Query: 121 FCVERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYN 179 F VERG+ ++ ++ + + VTA L + + +PE T++ G V+V C +N Sbjct: 131 FRVERGSRVRHSFLSNAFFLKVTA---LTKKPDVYIPE--TLEPGQPVTVICV-----FN 180 Query: 180 WTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFL-LLGDPQTNNCSLS--IR 236 W S+ GA + +P +H L PQ ++ L+ + Sbjct: 181 WAFKKCPAPSFSWTGAAL---------SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVD 231 Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296 +RKG S + ++ + I +S T+ + I ++ G L C Sbjct: 232 FSRKGVSAQRTVRLRVAYAPKDLIIS-ISHDNTSALELQGNVIYLEVQKGQFLRLLC--- 287 Query: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354 A + P T++W+ +SS P R+ L L TC+ + Sbjct: 288 -AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQ 344 Query: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414 +A+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT Sbjct: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404 Query: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPI 474 T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+ K+ Sbjct: 405 RWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH----WKLEHG 460 Query: 475 SGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQG 534 G+ LGA GAG AL+ C++ V+ CRK++ + A +D + G SQG Sbjct: 461 GGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRA-----AAEQDVPSTLGPISQG 515 Query: 535 PLIESPADDSPPHHAPPALATPSP---EEGEIQYASLSFHKARPQYPQEQEAIG-YEYSE 590 E A S H PP AT +P EE E+ YASLSF R P +QEA EYSE Sbjct: 516 HQHECSAGSS-QDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSE 574 Query: 591 INI 593 I I Sbjct: 575 IKI 577 >gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] Length = 364 Score = 287 bits (735), Expect = 2e-77 Identities = 140/251 (55%), Positives = 176/251 (70%) Query: 153 LEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKV 212 L+V ESVTVQEGLCV VPC+ +P + +SPV+G WF+EGA I D PVATN +V Sbjct: 23 LQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEV 82 Query: 213 QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT 272 QE+T GRF LLGDP NNCSLSI DAR+ D+G Y+F++ERGS K++Y +LSVHVT LT Sbjct: 83 QEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLT 142 Query: 273 HMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQ 332 H P IPGTLE GH +NLTCSV WACEQGTPP +W+ A+ +SL P T SS+L + P+ Sbjct: 143 HRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPR 202 Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392 PQDHGT+LTCQV GAGVT R ++LN++Y PQN T +F GDG+ R G + Sbjct: 203 PQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAI 262 Query: 393 EGQSLHLVCAV 403 G + + A+ Sbjct: 263 GGAGVTALLAL 273 Score = 150 bits (380), Expect = 2e-36 Identities = 86/189 (45%), Positives = 120/189 (63%), Gaps = 14/189 (7%) Query: 4 LLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYW 63 LLLLLP L G + ++ L +Q+SVTVQEGLCV V C+F +P + + PVHGYW Sbjct: 3 LLLLLPLLWAGALAM--DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYW 60 Query: 64 FRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCV 123 FR G +SR+ PVATN + VQEET+ RF LLGDP +C+LSI D R D G+Y F + Sbjct: 61 FREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRM 120 Query: 124 ERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY-------P 176 ERG+ K++YK QLSV+VT DL R ++ +P T++ G ++ CSV + P Sbjct: 121 ERGSTKYSYKSPQLSVHVT---DLTHRPKILIPG--TLEPGHSKNLTCSVSWACEQGTPP 175 Query: 177 HYNWTASSP 185 ++W +++P Sbjct: 176 IFSWLSAAP 184 Score = 70.1 bits (170), Expect = 5e-12 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 40/222 (18%) Query: 394 GQSLHLVCAV----DSNPPARLSWTWGSLT-LSPSQSSNLGVLELPRVHVKDEG-EFTCR 447 G S +L C+V + P SW + T L P + + ++ PR +D G TC+ Sbjct: 156 GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRP--QDHGTNLTCQ 213 Query: 448 AQNPLGSQHISLSLSLQNEY--------------TGKMRPISGVTLGAFGGAGATALVFL 493 + ++ L Y +GK +GV GA GGAG TAL+ L Sbjct: 214 VKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLAL 273 Query: 494 YFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSAS----QGPLIESPADDSPPHHA 549 C+IF +V++ R+K+AR AVG DT + GSAS + + P + S A Sbjct: 274 CLCLIFFIVKTHRRKAARTAVGRNDT-----HPTTGSASPKHQKKSKLHGPTETSSCSGA 328 Query: 550 PPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEI 591 P + + E+ YASL+FH P + EYSE+ Sbjct: 329 APTVEM----DEELHYASLNFHGMNP-----SKDTSTEYSEV 361 >gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] Length = 697 Score = 272 bits (696), Expect = 6e-73 Identities = 153/336 (45%), Positives = 199/336 (59%), Gaps = 9/336 (2%) Query: 137 LSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGAD 196 LS + SQ + R+ + V ESV V EGLC+SVPCS YP +WT S+P YG WFK + Sbjct: 7 LSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWFKAVTE 66 Query: 197 IPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR- 255 PVATN S +V+ T GRF L GDP NCSL IRDA+ D +Y+F+VERGS Sbjct: 67 TTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYV 126 Query: 256 KWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVS 315 ++N++ D + VTALT P IP TLE G P + C WA E+ PP+ +W GA++S Sbjct: 127 RYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALS 186 Query: 316 S--LDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF 373 S PT + S+LS P+PQDH T LTC V GV+ R VRL ++Y P++L +++ Sbjct: 187 SQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISIS 246 Query: 374 QGDGTASTTLRNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN---L 428 + + A G+ L +GQ L L+CA DS PPA LSW + LS S L Sbjct: 247 RDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL 306 Query: 429 GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 G LELP V D G +TCRA+N LGSQ +L LS+Q Sbjct: 307 G-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341 Score = 254 bits (648), Expect = 2e-67 Identities = 175/469 (37%), Positives = 247/469 (52%), Gaps = 38/469 (8%) Query: 6 LLLPPLLCGRVGAKEQKD--YLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYW 63 +LLP LL +G + D + + +Q+SV V EGLC+SV CSFSYP+ WT S P +GYW Sbjct: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60 Query: 64 FRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCV 123 F+A ++ PVATN+ +R V+ TR RF L GDP +C+L IRD + D Y F V Sbjct: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120 Query: 124 ERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTA 182 ERG+ +++N+ D + VTA L + + +PE T++ G V+V C +NW Sbjct: 121 ERGSYVRYNFMNDGFFLKVTA---LTQKPDVYIPE--TLEPGQPVTVICV-----FNWAF 170 Query: 183 SSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLG---DPQTNNCSLS--IRD 237 S+ GA + S + + T F +L PQ +N L+ + Sbjct: 171 EECPPPSFSWTGAAL-----------SSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDF 219 Query: 238 ARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGT-LESGHPRNLTCSVP 296 +RKG S + ++ + + + AL P ++P + G L C Sbjct: 220 SRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLC--- 276 Query: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354 A + P T++W+ +SS P R L L TC+ + Sbjct: 277 -AADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAE--NRLGSQQ 333 Query: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414 RA+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT Sbjct: 334 RALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWT 393 Query: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463 LSPSQ S+ GVLELPRV V+ EGEFTC A++PLGSQH+SLSLS+ Sbjct: 394 QRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442 Score = 45.8 bits (107), Expect = 1e-04 Identities = 58/225 (25%), Positives = 91/225 (40%), Gaps = 30/225 (13%) Query: 393 EGQSLHLVCAVDSNPPARLSWTWG-----------SLTLSPSQSSNLGVLELPRVHVKDE 441 E + LH C+ ++P L W G S ++PS + L Sbjct: 456 EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSS 515 Query: 442 G-EFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFV 500 G C A N G+Q S+ L L ++ K + + GAF G G TAL+FL +I + Sbjct: 516 GLRLRCEAWNVHGAQSGSI-LQLPDK---KGLISTAFSNGAFLGIGITALLFLCLALIIM 571 Query: 501 VV---RSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH--HAPPALAT 555 + R + ++ RP T ++ N V + GPL + + P+ P Sbjct: 572 KILPKRRTQTETPRPRFSRHSTILDYINVV---PTAGPLAQKRNQKATPNSPRTPLPPGA 628 Query: 556 PSPE-----EGEIQYASLSFHKARPQYPQEQEA-IGYEYSEINIP 594 PSPE + + Q S K+ Q P+ QE+ Y+ +N P Sbjct: 629 PSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLNFP 673 >gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo sapiens] Length = 698 Score = 239 bits (609), Expect = 7e-63 Identities = 137/320 (42%), Positives = 180/320 (56%), Gaps = 7/320 (2%) Query: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210 Y L+V V V EGLCV V C++ YP W S+ YG WFK PVATN S Sbjct: 34 YSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSR 93 Query: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHVT 269 +V+ T RF L GDP +CSL IRDA++ D Y+F+VERGSR + +++ + + VT Sbjct: 94 EVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVT 153 Query: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSS--LDPTITRSSML 327 ALT P IP TLE G P + C WA ++ P+ +W GA++S P+ + S+L Sbjct: 154 ALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVL 213 Query: 328 SLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGS 387 S P PQDH T LTC V GV+ R VRL ++Y P++L +++ + +A N Sbjct: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273 Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQS---SNLGVLELPRVHVKDEGEF 444 L V +GQ L L+CA DS PPA LSW LS S LG LEL V D G + Sbjct: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332 Query: 445 TCRAQNPLGSQHISLSLSLQ 464 TCRA+N LGSQ +L LS+Q Sbjct: 333 TCRAENRLGSQQQALDLSVQ 352 Score = 233 bits (595), Expect = 3e-61 Identities = 169/469 (36%), Positives = 240/469 (51%), Gaps = 34/469 (7%) Query: 1 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60 MLLL LLLP L G + + Y L +Q+ V V EGLCV V C+ SYP++GW S + Sbjct: 13 MLLLPLLLPVLGAGSLN--KDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAY 70 Query: 61 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120 GYWF+ PVATNN +R V+ TRDRF L GDP C+L IRD + D Y Sbjct: 71 GYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYF 130 Query: 121 FCVERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYN 179 F VERG+ ++ ++ + + VTA L + + +PE T++ G V+V C +N Sbjct: 131 FRVERGSRVRHSFLSNAFFLKVTA---LTKKPDVYIPE--TLEPGQPVTVICV-----FN 180 Query: 180 WTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFL-LLGDPQTNNCSLS--IR 236 W S+ GA + +P +H L PQ ++ L+ + Sbjct: 181 WAFKKCPAPSFSWTGAAL---------SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVD 231 Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296 +RKG S + ++ + I +S T+ + I ++ G L C Sbjct: 232 FSRKGVSAQRTVRLRVAYAPKDLIIS-ISHDNTSALELQGNVIYLEVQKGQFLRLLC--- 287 Query: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354 A + P T++W+ +SS P R+ L L TC+ + Sbjct: 288 -AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQ 344 Query: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414 +A+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT Sbjct: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404 Query: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463 T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+ Sbjct: 405 RWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453 Score = 92.4 bits (228), Expect = 1e-18 Identities = 113/392 (28%), Positives = 159/392 (40%), Gaps = 68/392 (17%) Query: 233 LSIRDARKGDSGKYYFQVER--GSRKW------NYIYDKLSVHV-----TALTHMPTFSI 279 L +R R GDSG+Y + E GS++ Y + L V V T L ++ + Sbjct: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378 Query: 280 PGTLESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHG 337 LE G L C P ++W G +V P+ +L L P +H Sbjct: 379 LPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPS--DPGVLELPPIQMEHE 431 Query: 338 TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397 TC P ++ + L++ YPPQ L G + S E + L Sbjct: 432 GEFTCHAQHPLGSQHVS--LSLSVHYPPQLL-----------------GPSCS-WEAEGL 471 Query: 398 HLVCAVDSNPPARLSW-----------TWGSLTLSPSQSSNLGVLELPRVHVKDEG-EFT 445 H C+ ++P L W + GS ++PS + L G Sbjct: 472 HCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLR 531 Query: 446 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSC 505 C+A N G+Q S+ L GK+ G+ LGA GAG AL+ C++ V+ C Sbjct: 532 CKAWNVHGAQSGSVFQLLP----GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKIC 587 Query: 506 RKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSP---EEGE 562 RK++ + A +D + G SQG E A S H PP AT +P EE E Sbjct: 588 RKEARKRA-----AAEQDVPSTLGPISQGHQHECSAGSS-QDHPPPGAATYTPGKGEEQE 641 Query: 563 IQYASLSFHKARPQYPQEQEAIG-YEYSEINI 593 + YASLSF R P +QEA EYSEI I Sbjct: 642 LHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673 >gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] Length = 237 Score = 149 bits (376), Expect = 7e-36 Identities = 69/133 (51%), Positives = 88/133 (66%) Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330 LTH P IPGTLE GH +NLTCSV WACEQGTPP +W+ A+ +SL P T SS+L + Sbjct: 14 LTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIIT 73 Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390 P+PQDHGT+LTCQV GAGVT R ++LN++Y PQN T +F GDG+ R G Sbjct: 74 PRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHG 133 Query: 391 VLEGQSLHLVCAV 403 + G + + A+ Sbjct: 134 AIGGAGVTALLAL 146 Score = 70.1 bits (170), Expect = 5e-12 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 40/222 (18%) Query: 394 GQSLHLVCAV----DSNPPARLSWTWGSLT-LSPSQSSNLGVLELPRVHVKDEG-EFTCR 447 G S +L C+V + P SW + T L P + + ++ PR +D G TC+ Sbjct: 29 GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRP--QDHGTNLTCQ 86 Query: 448 AQNPLGSQHISLSLSLQNEY--------------TGKMRPISGVTLGAFGGAGATALVFL 493 + ++ L Y +GK +GV GA GGAG TAL+ L Sbjct: 87 VKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLAL 146 Query: 494 YFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSAS----QGPLIESPADDSPPHHA 549 C+IF +V++ R+K+AR AVG DT + GSAS + + P + S A Sbjct: 147 CLCLIFFIVKTHRRKAARTAVGRNDT-----HPTTGSASPKHQKKSKLHGPTETSSCSGA 201 Query: 550 PPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEI 591 P + + E+ YASL+FH P + EYSE+ Sbjct: 202 APTVEM----DEELHYASLNFHGMNP-----SKDTSTEYSEV 234 >gi|11225258 myelin associated glycoprotein isoform a precursor [Homo sapiens] Length = 626 Score = 118 bits (296), Expect = 1e-26 Identities = 95/385 (24%), Positives = 162/385 (42%), Gaps = 41/385 (10%) Query: 155 VPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQE 214 +P S++ EG CVS+PC +P + + V+G W+ PV + + V E Sbjct: 26 MPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHE 83 Query: 215 DTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM 274 GR LLGD NC+L + + GKYYF+ + G Y + + S V + + Sbjct: 84 SFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYN-QYTFSEHS--VLDIVNT 140 Query: 275 PTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMG----------ASVSSLDPTITRS 324 P +P + +G ++C VP C + P ++W+G + + T + Sbjct: 141 PNIVVPPEVVAGTEVEVSCMVPDNCPE-LRPELSWLGHEGLGEPAVLGRLREDEGTWVQV 199 Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384 S+L +P + +G L CQ + P + +++ YPP + M Sbjct: 200 SLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEM-------------- 245 Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444 S++ +EG + L+C DSNPP L+W L + + +L +LEL V ++G + Sbjct: 246 -NSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESL-LLELEEVTPAEDGVY 303 Query: 445 TCRAQNPLGSQHISLSLSL-----QNEYTGKMRPISGVTLGAF----GGAGATALVFLYF 495 C A+N G + ++ LS+ + G M + G T+ +F Sbjct: 304 ACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEK 363 Query: 496 CIIFVVVRSCRKKSARPAVGVGDTG 520 I+ V+ + PAV D G Sbjct: 364 QILSTVIYESELQLELPAVSPEDDG 388 Score = 83.2 bits (204), Expect = 6e-16 Identities = 111/469 (23%), Positives = 180/469 (38%), Gaps = 66/469 (14%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 ++ L PL + A + M S++ EG CVS+ C F +P A VHG Sbjct: 1 MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAV--VHGV 58 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 W+ + PV + + V E + R LLGD ++CTL + + G Y F Sbjct: 59 WYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFR 118 Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVT----VQEGLCVSVPCSVLYPHY 178 + G Y+Q + + + D+++ + VP V V+ V C L P Sbjct: 119 GDLGG------YNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPEL 172 Query: 179 NWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED--THGRFLLLGDPQTNNCSLSIR 236 +W EG P G+++ED T + LL T + R Sbjct: 173 SWLG---------HEGLGEP--------AVLGRLREDEGTWVQVSLLHFVPTREAN-GHR 214 Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296 + Q E G + Y + V + + +E H +L C Sbjct: 215 LGCQASFPNTTLQFE-GYASMDVKYPPVIVEMNSSVE--------AIEGSHV-SLLC--- 261 Query: 297 WACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTR 355 + PP +TWM + L + S +L L P + G G R Sbjct: 262 -GADSNPPPLLTWM-RDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQD---NR 316 Query: 356 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW 415 V L++ Y P T+ NG+ ++V EG+++ ++C+ SNP L+ Sbjct: 317 TVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCSTQSNPDPILTIFK 361 Query: 416 GSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 LS + LELP V +D+GE+ C A+N G + + +LS++ Sbjct: 362 EKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVE 410 >gi|18104957 myelin associated glycoprotein isoform b precursor [Homo sapiens] Length = 582 Score = 118 bits (296), Expect = 1e-26 Identities = 95/385 (24%), Positives = 162/385 (42%), Gaps = 41/385 (10%) Query: 155 VPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQE 214 +P S++ EG CVS+PC +P + + V+G W+ PV + + V E Sbjct: 26 MPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHE 83 Query: 215 DTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM 274 GR LLGD NC+L + + GKYYF+ + G Y + + S V + + Sbjct: 84 SFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYN-QYTFSEHS--VLDIVNT 140 Query: 275 PTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMG----------ASVSSLDPTITRS 324 P +P + +G ++C VP C + P ++W+G + + T + Sbjct: 141 PNIVVPPEVVAGTEVEVSCMVPDNCPE-LRPELSWLGHEGLGEPAVLGRLREDEGTWVQV 199 Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384 S+L +P + +G L CQ + P + +++ YPP + M Sbjct: 200 SLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEM-------------- 245 Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444 S++ +EG + L+C DSNPP L+W L + + +L +LEL V ++G + Sbjct: 246 -NSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESL-LLELEEVTPAEDGVY 303 Query: 445 TCRAQNPLGSQHISLSLSL-----QNEYTGKMRPISGVTLGAF----GGAGATALVFLYF 495 C A+N G + ++ LS+ + G M + G T+ +F Sbjct: 304 ACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEK 363 Query: 496 CIIFVVVRSCRKKSARPAVGVGDTG 520 I+ V+ + PAV D G Sbjct: 364 QILSTVIYESELQLELPAVSPEDDG 388 Score = 83.2 bits (204), Expect = 6e-16 Identities = 111/469 (23%), Positives = 180/469 (38%), Gaps = 66/469 (14%) Query: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62 ++ L PL + A + M S++ EG CVS+ C F +P A VHG Sbjct: 1 MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAV--VHGV 58 Query: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122 W+ + PV + + V E + R LLGD ++CTL + + G Y F Sbjct: 59 WYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFR 118 Query: 123 VERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVT----VQEGLCVSVPCSVLYPHY 178 + G Y+Q + + + D+++ + VP V V+ V C L P Sbjct: 119 GDLGG------YNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPEL 172 Query: 179 NWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED--THGRFLLLGDPQTNNCSLSIR 236 +W EG P G+++ED T + LL T + R Sbjct: 173 SWLG---------HEGLGEP--------AVLGRLREDEGTWVQVSLLHFVPTREAN-GHR 214 Query: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296 + Q E G + Y + V + + +E H +L C Sbjct: 215 LGCQASFPNTTLQFE-GYASMDVKYPPVIVEMNSSVE--------AIEGSHV-SLLC--- 261 Query: 297 WACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTR 355 + PP +TWM + L + S +L L P + G G R Sbjct: 262 -GADSNPPPLLTWM-RDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQD---NR 316 Query: 356 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW 415 V L++ Y P T+ NG+ ++V EG+++ ++C+ SNP L+ Sbjct: 317 TVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCSTQSNPDPILTIFK 361 Query: 416 GSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 LS + LELP V +D+GE+ C A+N G + + +LS++ Sbjct: 362 EKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVE 410 >gi|13489095 sialoadhesin precursor [Homo sapiens] Length = 1709 Score = 95.5 bits (236), Expect = 1e-19 Identities = 82/310 (26%), Positives = 135/310 (43%), Gaps = 33/310 (10%) Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215 P+ V +G C+ +PC +P + + W+ D V +++ K+ E Sbjct: 26 PQDVQGVKGSCLLIPCIFSFPA-DVEVPDGITAIWYY---DYSGQRQVVSHSADPKLVEA 81 Query: 216 T-HGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGS-RKWNYIYDKLSVHVTALTH 273 GR +G+P+ C+L ++D + DSG Y F+ E +W+ + L V VT Sbjct: 82 RFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTL-VTVTEEPR 140 Query: 274 MPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGA--------SVSSLDPT-ITRS 324 +PT + P L G + CS P+ C Q + W G + +PT + Sbjct: 141 VPTIASPVELLEGTEVDFNCSTPYVCLQ-EQVRLQWQGQDPARSVTFNSQKFEPTGVGHL 199 Query: 325 SMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384 L + QDHG L CQ+++ A + L + Y P+ + + L Sbjct: 200 ETLHMAMSWQDHGRILRCQLSV--ANHRAQSEIHLQVKYAPKGVKI------------LL 245 Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444 + S ++L G+ + L C V+S+ PA S W L + GVL LP+ D G + Sbjct: 246 SPSGRNILPGELVTLTCQVNSSYPAVSSIKW--LKDGVRLQTKTGVLHLPQAAWSDAGVY 303 Query: 445 TCRAQNPLGS 454 TC+A+N +GS Sbjct: 304 TCQAENGVGS 313 Score = 68.9 bits (167), Expect = 1e-11 Identities = 71/245 (28%), Positives = 99/245 (40%), Gaps = 42/245 (17%) Query: 229 NNCSLSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPG-TLES 285 N L I A D G Y + G + +D +V+V PG T+ Sbjct: 1048 NTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQAVNVQVW--------PGATVRE 1099 Query: 286 GHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQ---DHGTSLTC 342 G NLTC V W T TW LD IP P TS C Sbjct: 1100 GQLVNLTCLV-WTTHPAQL-TYTWYQDGQQRLDA--------HSIPLPNVTVRDATSYRC 1149 Query: 343 QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402 V PG ++R + L++ Y P+NL +T L GQ ++C Sbjct: 1150 GVGPPGRAPRLSRPITLDVLYAPRNLRLTYL---------------LESHGGQLALVLCT 1194 Query: 403 VDSNPPARLSWTWGSLTLSPSQSS---NLGVLELPRVHVKDEGEFTCRAQNPLGSQHISL 459 VDS PPA+L+ + L+ S ++ N LEL +DEG ++C A++PLG + SL Sbjct: 1195 VDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSL 1254 Query: 460 SLSLQ 464 L L+ Sbjct: 1255 ELRLE 1259 Score = 63.2 bits (152), Expect = 7e-10 Identities = 69/272 (25%), Positives = 98/272 (36%), Gaps = 49/272 (18%) Query: 213 QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTA 270 Q +HGRF + N+ L +R+ GDSG Y + GS + + V Sbjct: 843 QVPSHGRFQ--AKAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQV 900 Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330 S L+ G L+C V +GT G + R + ++L Sbjct: 901 -------SPSPELQEGQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLT 953 Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRA-VRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389 H CQ PG+ T A + L++SY P+++T+T G L Sbjct: 954 QAGAYH-----CQAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGL------ 1002 Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGS-LTLSPSQSSNLGVLELPRVHV---------- 438 L+C VDS+PPA+L G L S Q PR+HV Sbjct: 1003 ---------LLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLE 1053 Query: 439 ------KDEGEFTCRAQNPLGSQHISLSLSLQ 464 +DEG + C A N LG S Q Sbjct: 1054 IHGAMLEDEGVYICEASNTLGQASASADFDAQ 1085 Score = 57.4 bits (137), Expect = 4e-08 Identities = 95/447 (21%), Positives = 168/447 (37%), Gaps = 77/447 (17%) Query: 21 QKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNN 80 Q + ++ + V +G C+ + C FS+P + D + W+ D+ + V+ + Sbjct: 18 QASWGVSSPQDVQGVKGSCLLIPCIFSFPADV-EVPDGITAIWYY--DYSGQRQVVSHSA 74 Query: 81 PARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNM-KWNYKYDQLSV 139 + V+ R R +G+P+++ C L ++D + D+G+Y F E + +W+ D Sbjct: 75 DPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWS---DVKGT 131 Query: 140 NVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLY------PHYNWTASSPVYGSWFKE 193 VT +++ + V + EG V CS Y W P F Sbjct: 132 LVTVTEEPRVP---TIASPVELLEGTEVDFNCSTPYVCLQEQVRLQWQGQDPARSVTFNS 188 Query: 194 GADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERG 253 P + +D HGR L C LS+ + R + + QV+ Sbjct: 189 QKFEPTGVGHLETLHMAMSWQD-HGRIL--------RCQLSVANHRA--QSEIHLQVKYA 237 Query: 254 SRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGAS 313 + + ++ +PG L + LTC V +I W+ Sbjct: 238 PKGVKILLSPSGRNI----------LPGELVT-----LTCQV--NSSYPAVSSIKWLKDG 280 Query: 314 VSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF 373 V T++ +L L TCQ G G ++ PP +++ +F Sbjct: 281 VR----LQTKTGVLHLPQAAWSDAGVYTCQAE-NGVG---------SLVSPP--ISLHIF 324 Query: 374 QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW--GSLTLSPSQSSNLGVL 431 + S A +LE Q++ LVC + P+ L ++W + L + S L Sbjct: 325 MAEVQVS------PAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTL--- 375 Query: 432 ELPRVHV---KDEGEFTCRAQNPLGSQ 455 R+H+ D G + C QN GS+ Sbjct: 376 ---RLHLATRADTGFYFCEVQNVHGSE 399 Score = 53.1 bits (126), Expect = 7e-07 Identities = 48/200 (24%), Positives = 79/200 (39%), Gaps = 34/200 (17%) Query: 282 TLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLT 341 TL+ G NLTC+V G+P +W V + ++L+P + Sbjct: 718 TLQEGTEANLTCNVSREAA-GSPANFSWFRNGVLWAQGPL---ETVTLLPVARTDAALYA 773 Query: 342 CQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVC 401 C++ L AG ++ V L++ YPP ++ L + +G +C Sbjct: 774 CRI-LTEAGAQLSTPVLLSVLYPPDRPKLSAL---------------LDMGQGHMALFIC 817 Query: 402 AVDSNPPARLSWTWGSLTLSPS--------------QSSNLGVLELPRVHVKDEGEFTCR 447 VDS P A L+ G L+ S +N LE+ + + D G + C Sbjct: 818 TVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKLEVRELGLGDSGSYRCE 877 Query: 448 AQNPLGSQHISLSLSLQNEY 467 A N LGS + SL ++ + Sbjct: 878 ATNVLGSSNTSLFFQVRGAW 897 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 34/133 (25%) Query: 342 CQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVC 401 C LP G + V L + YPP+ TM VF G +L+ C Sbjct: 1511 CLAELP-TGAAASAPVMLRVLYPPKTPTMMVFVEP--------EGGLRGILD-------C 1554 Query: 402 AVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV----------------KDEGEFT 445 VDS P A L+ GS ++ SQ G P +HV D+GE+ Sbjct: 1555 RVDSEPLASLTLHLGSRLVASSQPQ--GAPAEPHIHVLASPNALRVDIEALRPSDQGEYI 1612 Query: 446 CRAQNPLGSQHIS 458 C A N LGS S Sbjct: 1613 CSASNVLGSASTS 1625 Score = 41.2 bits (95), Expect = 0.003 Identities = 54/239 (22%), Positives = 90/239 (37%), Gaps = 40/239 (16%) Query: 229 NNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHP 288 N L +R + D G Y + N + L + + P ++P G P Sbjct: 1222 NTLRLELRGPQPRDEGFYSCSARSPLGQANTSLE-LRLEGVRVILAPEAAVP----EGAP 1276 Query: 289 RNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPG 348 +TC+ P A P TW + ++ LS + + H + +CQ Sbjct: 1277 ITVTCADPAA---HAPTLYTWYHNGRWLQEGP---AASLSFLVATRAHAGAYSCQAQ-DA 1329 Query: 349 AGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPP 408 G +R L + Y PQ+ ++ F+ S + + C VDS PP Sbjct: 1330 QGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAV---------------IQCTVDSEPP 1374 Query: 409 ARLSWTWGSLTLSPSQ-----SSNLGVLELP----RVHVKD----EGEFTCRAQNPLGS 454 A L+ + L+ S +S G +++ R+ V+D + + C AQN LGS Sbjct: 1375 AELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDDTYVCTAQNLLGS 1433 Score = 37.4 bits (85), Expect = 0.039 Identities = 63/266 (23%), Positives = 98/266 (36%), Gaps = 50/266 (18%) Query: 224 GDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTL 283 G N+ L IRD + DSG+Y + L H A + S + Sbjct: 467 GTSGPNSLRLEIRDLEETDSGEYKCSA---TNSLGNATSTLDFHANAARLL--ISPAAEV 521 Query: 284 ESGHPRNLTCSVPWACEQGTPPT----ITW-MGASVSSLDPTITRSSMLSLIPQPQDHGT 338 G +V +C G PT +W + ++ P SS+L D G Sbjct: 522 VEGQ------AVTLSCRSGLSPTPDARFSWYLNGALLHEGPG---SSLLLPAASSTDAG- 571 Query: 339 SLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLH 398 S C+ + + L + YPP+ T T T + A G+ Sbjct: 572 SYHCRARDGHSASGPSSPAVLTVLYPPRQPTFT----------TRLDLDAAGAGAGRRGL 621 Query: 399 LVCAVDSNPPARLSW------------------TWG--SLTLSPSQSSNLGVLELPRVHV 438 L+C VDS+PPARL T G S + +++ NL +E+ + Sbjct: 622 LLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLL 681 Query: 439 KDEGEFTCRAQNPLGSQHISLSLSLQ 464 ++EG + C A N LG+ S + + Q Sbjct: 682 EEEGLYLCEASNALGNASTSATFNGQ 707 >gi|157168355 CD22 molecule [Homo sapiens] Length = 847 Score = 85.5 bits (210), Expect = 1e-16 Identities = 76/317 (23%), Positives = 130/317 (41%), Gaps = 34/317 (10%) Query: 149 SRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTP 208 S++ E PE++ EG CV +PC+ + + + + + + +T Sbjct: 22 SKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFHNPEYNKNTSKFDGTRLYESTK 81 Query: 209 SGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHV 268 GKV + R LGD + NC+LSI DSG+ ++E + KW +++ ++V Sbjct: 82 DGKVPSEQK-RVQFLGD-KNKNCTLSIHPVHLNDSGQLGLRMESKTEKW---MERIHLNV 136 Query: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSM-- 326 + P +P ++ LTC + ++C G P + W+ V +T +S+ Sbjct: 137 SERPFPPHIQLPPEIQESQEVTLTCLLNFSC-YGYPIQLQWLLEGVPMRQAAVTSTSLTI 195 Query: 327 --------LSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGT 378 L PQ HG +TCQ+ V+LN+ + P+ L + V D Sbjct: 196 KSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKHTPK-LEIKVTPSDAI 254 Query: 379 ASTTLRNGSALSVLEGQSLHLVCAVDSNPP--ARLSWTWGSLTLSPSQSSNLGVLELPRV 436 V EG S+ + C V S+ P +SW +L + N L L V Sbjct: 255 ------------VREGDSVTMTCEVSSSNPEYTTVSWLKDGTSL---KKQNTFTLNLREV 299 Query: 437 HVKDEGEFTCRAQNPLG 453 G++ C+ N +G Sbjct: 300 TKDQSGKYCCQVSNDVG 316 Score = 50.4 bits (119), Expect = 4e-06 Identities = 84/383 (21%), Positives = 150/383 (39%), Gaps = 57/383 (14%) Query: 92 RFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRY 151 R LGD +NK+CTLSI +D+G +E KW +++ +NV+ + Sbjct: 91 RVQFLGD-KNKNCTLSIHPVHLNDSGQLGLRMESKTEKW---MERIHLNVSERP-----F 141 Query: 152 RLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGK 211 + +QE V++ C + + Y + P+ W EG +P T+T Sbjct: 142 PPHIQLPPEIQESQEVTLTCLLNFSCYGY----PIQLQWLLEG--VPMRQAAVTST--SL 193 Query: 212 VQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY-DKLSVHVTA 270 + R L PQ ++ + + GK+ + + + N + KL + VT Sbjct: 194 TIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKF---LSNDTVQLNVKHTPKLEIKVT- 249 Query: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLS 328 P+ +I + G +TC V + + T T++W+ G S+ + T T L+ Sbjct: 250 ----PSDAI---VREGDSVTMTCEVSSSNPEYT--TVSWLKDGTSLKKQN-TFT----LN 295 Query: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388 L +D CQV+ G + V L + Y P+ T+ + Sbjct: 296 LREVTKDQSGKYCCQVS-NDVGPGRSEEVFLQVQYAPEPSTVQILHS------------- 341 Query: 389 LSVLEGQSLHLVCAVDSNP-PARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCR 447 +EG + +C +NP P +W + Q + +P++ G ++C Sbjct: 342 -PAVEGSQVEFLCMSLANPLPTNYTWYHNGKEM---QGRTEEKVHIPKILPWHAGTYSCV 397 Query: 448 AQNPLGSQHISLSLSLQNEYTGK 470 A+N LG+ L +Y K Sbjct: 398 AENILGTGQRGPGAELDVQYPPK 420 Score = 47.4 bits (111), Expect = 4e-05 Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 21/130 (16%) Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392 P+D G S +C V G T ++A L + Y P+ L +++ GD V+ Sbjct: 563 PEDAG-SYSCWVN-NSIGQTASKAWTLEVLYAPRRLRVSMSPGD-------------QVM 607 Query: 393 EGQSLHLVCAVDSNPP-ARLSW-TWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450 EG+S L C D+NPP + +W W + +L P S L L V V+ G + C+ N Sbjct: 608 EGKSATLTCESDANPPVSHYTWFDWNNQSL-PYHSQK---LRLEPVKVQHSGAYWCQGTN 663 Query: 451 PLGSQHISLS 460 +G LS Sbjct: 664 SVGKGRSPLS 673 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 59.3 bits (142), Expect = 1e-08 Identities = 80/360 (22%), Positives = 130/360 (36%), Gaps = 46/360 (12%) Query: 106 LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165 L I + SDAGTYV C+ + + K ++ V+ A + + E E +TV+ G Sbjct: 3170 LQISSAKPSDAGTYV-CLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGH 3227 Query: 166 CVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGD 225 ++ CS T S W K + +PW +++ DT Sbjct: 3228 TATLRCSA-------TGSPAPTIHWSKLRSPLPWQ---------HRLEGDT--------- 3262 Query: 226 PQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLES 285 L I + DSG+Y + + + + +HV + + T ++++ Sbjct: 3263 -------LIIPRVAQQDSGQY---ICNATSPAGHAEATIILHVESPPYATTVPEHASVQA 3312 Query: 286 GHPRNLTCSVPWACEQGTPP-TITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQV 344 G L C GTPP T W S R+ +L + C+V Sbjct: 3313 GETVQLQCLA-----HGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRV 3367 Query: 345 TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404 T +L + PP +L T T + + + G S+ CAV Sbjct: 3368 TNKVGSAEAF--AQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSI-GASVEFHCAVP 3424 Query: 405 SNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 S+ +L W L P S GVL + + +G + C+A P G S L +Q Sbjct: 3425 SDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQ 3484 Score = 56.2 bits (134), Expect = 8e-08 Identities = 75/259 (28%), Positives = 110/259 (42%), Gaps = 49/259 (18%) Query: 227 QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTAL-----THMPTFSIPG 281 Q + L + DSG+Y +V S + SV VT +H + P Sbjct: 2482 QVHGSRLRLLQVTPADSGEYVCRVVGSSGT-----QEASVLVTIQQRLSGSHSQGVAYPV 2536 Query: 282 TLES-------GHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQ 332 +ES GH +L C V P TITW G S+ S + S L IPQ Sbjct: 2537 RIESSSASLANGHTLDLNCLVA----SQAPHTITWYKRGGSLPSRHQIV--GSRLR-IPQ 2589 Query: 333 --PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTA-----STTLR- 384 P D G C V+ GAG T +L +T+ QG G++ S +R Sbjct: 2590 VTPADSG-EYVCHVS-NGAGSRET------------SLIVTI-QGSGSSHVPSVSPPIRI 2634 Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444 S+ +V+EGQ+L L C V P A ++W +L ++ L L ++ V D GE+ Sbjct: 2635 ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEY 2694 Query: 445 TCRAQNPLGSQHISLSLSL 463 CRA N + + S+ +S+ Sbjct: 2695 VCRANNNIDALEASIVISV 2713 Score = 55.1 bits (131), Expect = 2e-07 Identities = 94/383 (24%), Positives = 141/383 (36%), Gaps = 66/383 (17%) Query: 106 LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165 L+IR+ + SDAGTYV C G+ + +++V AS L + P +TVQ G Sbjct: 1825 LTIRNVQLSDAGTYV-CT--GSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1881 Query: 166 CVSVPCSVL---YPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLL 222 CS P WT G +P + HG L Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGP---------GGQLP-------------AKAQIHGGILR 1919 Query: 223 LGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGT 282 L + + + + A +G+ QV R L VH + Sbjct: 1920 LPAVEPTDQAQYLCRAHSS-AGQ---QVARAV---------LHVHGGGGPRVQVSPERTQ 1966 Query: 283 LESGHPRNLTCSVPWACEQGTPP-TITWMGASVSSLDPTITRSSMLSLIPQPQ----DHG 337 + +G L C G P TITW R SL PQ + D Sbjct: 1967 VHAGRTVRLYCRAA-----GVPSATITW-------------RKEGGSLPPQARSERTDIA 2008 Query: 338 TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397 T L +T AG + A + + + + D + S+ SV EGQ+L Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068 Query: 398 HLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHI 457 L C V + A+++W +L P + L LP+V D GE+ CR +N G + Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEA 2128 Query: 458 SLSLS-LQNEYTG-KMRPISGVT 478 S+++S L ++G P+ G T Sbjct: 2129 SITVSVLHGTHSGPSYTPVPGST 2151 Score = 50.8 bits (120), Expect = 3e-06 Identities = 91/394 (23%), Positives = 150/394 (38%), Gaps = 69/394 (17%) Query: 106 LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165 L + +D+G YV V + + SV VT Q L + V V ++ Sbjct: 2488 LRLLQVTPADSGEYVCRVVGSSGT-----QEASVLVTIQQRLSGSHSQGVAYPVRIESSS 2542 Query: 166 CVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGD 225 L + + +P +W+K G +P R ++G Sbjct: 2543 ASLANGHTLDLNCLVASQAPHTITWYKRGGSLP-------------------SRHQIVGS 2583 Query: 226 PQTNNCSLSIRDARKGDSGKYYFQVERG--SRKWNYIYDKLSVHVTALTHMPTFSIPGTL 283 L I DSG+Y V G SR+ + I +++ + +H+P+ S P + Sbjct: 2584 ------RLRIPQVTPADSGEYVCHVSNGAGSRETSLI---VTIQGSGSSHVPSVSPPIRI 2634 Query: 284 ESGHP---RNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGT 338 ES P T + + ITW G S+ S + Q HG+ Sbjct: 2635 ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS---------------RHQTHGS 2679 Query: 339 SLTC-QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGT-----ASTTLRNGSALS-V 391 L Q+++ +G + RA NI ++ ++V G+ +S +R S+ S V Sbjct: 2680 HLRLHQMSVADSGEYVCRANN-NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHV 2738 Query: 392 LEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNP 451 EG++L L C V A+++W +L + L L V D GE+ CR Sbjct: 2739 AEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGS 2798 Query: 452 LGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGA 485 G S+ +++ E +G S V + A GGA Sbjct: 2799 SGPLEASVLVTI--EASGS----SAVHVPAPGGA 2826 Score = 47.4 bits (111), Expect = 4e-05 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 64/325 (19%) Query: 158 SVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTH 217 S TV EG + + C V + +W+K G +P Sbjct: 2253 SSTVAEGQTLDLSCVV-------AGQAHAQVTWYKRGGSLP------------------- 2286 Query: 218 GRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA-----LT 272 Q L I A D+G+Y + G ++V VT L Sbjct: 2287 ------ARHQVRGSRLYIFQASPADAGQYVCRASNGMEA------SITVTVTGTQGANLA 2334 Query: 273 HMPTFSIPGTLE-------SGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSS 325 + + P +E G +L C VP +TW S T S Sbjct: 2335 YPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHA----QVTWHKRGGSLPVRHQTHGS 2390 Query: 326 MLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLR 384 +L L P D G C+V G+ V + +V + I P + G T Sbjct: 2391 LLRLYQASPADSG-EYVCRVL--GSSVPLEASVLVTIE--PAGSVPAL----GVTPTVRI 2441 Query: 385 NGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEF 444 S+ V EGQ+L L C V A+++W +L + L L +V D GE+ Sbjct: 2442 ESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEY 2501 Query: 445 TCRAQNPLGSQHISLSLSLQNEYTG 469 CR G+Q S+ +++Q +G Sbjct: 2502 VCRVVGSSGTQEASVLVTIQQRLSG 2526 Score = 43.9 bits (102), Expect = 4e-04 Identities = 60/254 (23%), Positives = 97/254 (38%), Gaps = 23/254 (9%) Query: 227 QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTF---SIPGTL 283 QT+ L + DSG+Y V R + + + + + V+ P+ S+P + Sbjct: 2675 QTHGSHLRLHQMSVADSGEY---VCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRI 2731 Query: 284 ES-------GHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP-QPQD 335 ES G +L C VP +TW S TR S L L P D Sbjct: 2732 ESSSSHVAEGETLDLNCVVPGQAHA----QVTWHKRGGSLPSHHQTRGSRLRLHHVSPAD 2787 Query: 336 HGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQ 395 G C+V G+ + +V + I + G A S+ V EGQ Sbjct: 2788 SG-EYVCRVM--GSSGPLEASVLVTIEASGSSAVHV--PAPGGAPPIRIEPSSSRVAEGQ 2842 Query: 396 SLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455 +L L C V A+++W L + +L L +V D GE++C+ G+ Sbjct: 2843 TLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902 Query: 456 HISLSLSLQNEYTG 469 S+ ++++ G Sbjct: 2903 EASVLVTIEPSSPG 2916 Score = 43.5 bits (101), Expect = 5e-04 Identities = 59/241 (24%), Positives = 90/241 (37%), Gaps = 24/241 (9%) Query: 227 QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIY-------DKLSVHVTALTHMPTFSI 279 QT L + DSG+Y +V S +VHV A P I Sbjct: 2772 QTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRI 2831 Query: 280 PGT---LESGHPRNLTCSVPWACEQGTPPTITW--MGASVSSLDPTITRSSMLSLIPQPQ 334 + + G +L C VP +TW G ++ + L+ + P Sbjct: 2832 EPSSSRVAEGQTLDLKCVVPGQAHA----QVTWHKRGGNLPARHQVHGPLLRLNQV-SPA 2886 Query: 335 DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394 D G +CQVT G+ T+ +V + I + + G A S+ V EG Sbjct: 2887 DSG-EYSCQVT--GSSGTLEASVLVTI----EPSSPGPIPAPGLAQPIYIEASSSHVTEG 2939 Query: 395 QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 Q+L L C V A+++W +L ++ L L V D GE+ CRA + G Sbjct: 2940 QTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGP 2999 Query: 455 Q 455 + Sbjct: 3000 E 3000 Score = 42.7 bits (99), Expect = 0.001 Identities = 85/360 (23%), Positives = 132/360 (36%), Gaps = 68/360 (18%) Query: 106 LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL 165 L + SDAG Y+ C R + N +L V S+ + +E S +V+ G Sbjct: 1731 LHFPSVQPSDAGVYI-CTCRNLHQSNTSRAELLVTEAPSKPIT--VTVEEQRSQSVRPGA 1787 Query: 166 CVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGD 225 V+ C+ + SP Y + W T +GK+ Sbjct: 1788 DVTFICTA-------KSKSPAY--------TLVW-----TRLHNGKLPTRA--------- 1818 Query: 226 PQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLES 285 N L+IR+ + D+G Y V GS + ++HV A T S P + S Sbjct: 1819 -MDFNGILTIRNVQLSDAGTY---VCTGSNMFAMDQGTATLHVQA---SGTLSAP--VVS 1869 Query: 286 GHPRNLTCSVPWACE-----QGTP-PTITWMGASVSSLDPTITRSSMLSLIP--QPQDHG 337 HP LT E G+P PT+ W G L + +P +P D Sbjct: 1870 IHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQA 1929 Query: 338 TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397 L C+ AG + RAV + V G G + V G+++ Sbjct: 1930 QYL-CRAH-SSAGQQVARAV------------LHVHGGGGPRVQV--SPERTQVHAGRTV 1973 Query: 398 HLVCAVDSNPPARLSWTWGSLTLSP---SQSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 L C P A ++W +L P S+ +++ L +P + D G + C A +P G+ Sbjct: 1974 RLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT 2033 Score = 42.7 bits (99), Expect = 0.001 Identities = 87/390 (22%), Positives = 132/390 (33%), Gaps = 72/390 (18%) Query: 106 LSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRY----------RLEV 155 L + +D+G YV VE G+ K ++V+V Y R+E Sbjct: 2102 LRLPQVSPADSGEYVCRVENGS---GPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIE- 2157 Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215 P S V EG + + C V + +W K G +P + Sbjct: 2158 PSSSHVAEGQTLDLNCVV-------PGQAHAQVTWHKRGGSLP-------------ARHQ 2197 Query: 216 THGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWN---YIYDKLSVHVTALT 272 THG L L DSG+Y V S + + SV + Sbjct: 2198 THGSLLRL------------HQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIP 2245 Query: 273 HMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQ 332 + S T+ G +L+C V +TW S R S L + Sbjct: 2246 PVRIESSSSTVAEGQTLDLSCVVAGQAHA----QVTWYKRGGSLPARHQVRGSRLYIFQA 2301 Query: 333 PQDHGTSLTCQVTL---PGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389 C+ + VT+T N++YP G+ S+ Sbjct: 2302 SPADAGQYVCRASNGMEASITVTVTGTQGANLAYPA-----------GSTQPIRIEPSSS 2350 Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449 V EGQ+L L C V A+++W +L ++ +L L + D GE+ CR Sbjct: 2351 QVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRV- 2409 Query: 450 NPLGSQ-HISLSLSLQNEYTGKMRPISGVT 478 LGS + S+ + E G + P GVT Sbjct: 2410 --LGSSVPLEASVLVTIEPAGSV-PALGVT 2436 Score = 42.0 bits (97), Expect = 0.002 Identities = 87/361 (24%), Positives = 131/361 (36%), Gaps = 69/361 (19%) Query: 105 TLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEG 164 TL I +DAG Y+ CV Q+ V ++AS ++E S +V EG Sbjct: 2009 TLLIPAITTADAGFYL-CVATSPAGTAQARIQVVV-LSASDASPPPVKIE-SSSPSVTEG 2065 Query: 165 LCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLG 224 + + C V S+ +W++ G +P P +V HG L L Sbjct: 2066 QTLDLNCVV-------AGSAHAQVTWYRRGGSLP---------PHTQV----HGSRLRL- 2104 Query: 225 DPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM-PTFS-IPGT 282 PQ + DSG+Y +VE GS ++V V TH P+++ +PG+ Sbjct: 2105 -PQVS----------PADSGEYVCRVENGSGPKE---ASITVSVLHGTHSGPSYTPVPGS 2150 Query: 283 ------------LESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330 + G +L C VP +TW S T S+L L Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAH----AQVTWHKRGGSLPARHQTHGSLLRLH 2206 Query: 331 P-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSAL 389 P D G C V + + V + S P G S+ Sbjct: 2207 QVTPADSG-EYVCHVVGTSGPLEASVLVTIEASVIP-----------GPIPPVRIESSSS 2254 Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQ 449 +V EGQ+L L C V A+++W +L L + + D G++ CRA Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2314 Query: 450 N 450 N Sbjct: 2315 N 2315 Score = 40.4 bits (93), Expect = 0.005 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 14/149 (9%) Query: 328 SLIPQPQDHGTSLTC-QVTLPGAGVTMTRAVRLNISYPPQ-NLTMTVFQGD--------- 376 SL P Q HG+ L QV+ +G + R N S P + ++T++V G Sbjct: 2090 SLPPHTQVHGSRLRLPQVSPADSGEYVCRVE--NGSGPKEASITVSVLHGTHSGPSYTPV 2147 Query: 377 -GTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPR 435 G+ S+ V EGQ+L L C V A+++W +L ++ +L L + Sbjct: 2148 PGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQ 2207 Query: 436 VHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 V D GE+ C G S+ ++++ Sbjct: 2208 VTPADSGEYVCHVVGTSGPLEASVLVTIE 2236 Score = 35.8 bits (81), Expect = 0.11 Identities = 48/206 (23%), Positives = 74/206 (35%), Gaps = 21/206 (10%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRA 448 L+V G + L C+ +P + W+ L L +PRV +D G++ C A Sbjct: 3221 LTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNA 3280 Query: 449 QNPLGSQHISLSLSLQN-EYTGKMRPISGVTLGAFG-----GAGATALVFLYFCI----- 497 +P G ++ L +++ Y + + V G G L F + + Sbjct: 3281 TSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLP 3340 Query: 498 --------IFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHA 549 + R+ + S R V + + A A QGP PA P Sbjct: 3341 GRATARNELLHFERAAPEDSGRYRCRVTNK-VGSAEAFAQLLVQGPPGSLPATSIPAGST 3399 Query: 550 PPALATPSPEEGEIQYASLSFHKARP 575 P TP E I AS+ FH A P Sbjct: 3400 PTVQVTPQLETKSIG-ASVEFHCAVP 3424 Score = 33.9 bits (76), Expect = 0.44 Identities = 57/264 (21%), Positives = 98/264 (37%), Gaps = 41/264 (15%) Query: 227 QTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT----HMPTFSIP-- 280 QT+ L + DSG+Y + G ++V + + P SI Sbjct: 2970 QTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPP 3029 Query: 281 -GTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIP----QPQD 335 T++ G + C + + P ++ W + L+ + S S+I +P + Sbjct: 3030 SSTVQQGQDASFKCLIH---DGAAPISLEWKTRN-QELEDNVHISPNGSIITIVGTRPSN 3085 Query: 336 HGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQ 395 HGT C V GV + V L++ PP + ++ + V G+ Sbjct: 3086 HGT-YRC-VASNAYGVAQS-VVNLSVHGPP--------------TVSVLPEGPVWVKVGK 3128 Query: 396 SLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG------VLELPRVHVKDEGEFTCRAQ 449 ++ L C P + WT S T + + G VL++ D G + C AQ Sbjct: 3129 AVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQ 3188 Query: 450 NPLGSQHISLSLSLQNEYTGKMRP 473 N LG+ + + + TG M P Sbjct: 3189 NALGTAQKQVEVIVD---TGAMAP 3209 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 6/72 (8%) Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSW--TWGSLTLSP----SQSSNLGVLELPRVHVKDE 441 ++ GQ++ C P ++W WG + P + G L + V D+ Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 474 Query: 442 GEFTCRAQNPLG 453 G +TC A N G Sbjct: 475 GAYTCEAMNARG 486 Score = 31.6 bits (70), Expect = 2.2 Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 2/87 (2%) Query: 380 STTLRNGSALSVLEGQSLHLVCAVDSNPPA-RLSWTWGSLTLSPSQSSNL-GVLELPRVH 437 + T+ + SV G + +C S PA L WT P+++ + G+L + V Sbjct: 1772 TVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQ 1831 Query: 438 VKDEGEFTCRAQNPLGSQHISLSLSLQ 464 + D G + C N + +L +Q Sbjct: 1832 LSDAGTYVCTGSNMFAMDQGTATLHVQ 1858 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/60 (28%), Positives = 24/60 (40%) Query: 394 GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLG 453 G + C P +SW+ +L P +L LP V +D G + C A N G Sbjct: 3589 GSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQG 3648 >gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] Length = 1349 Score = 57.4 bits (137), Expect = 4e-08 Identities = 88/354 (24%), Positives = 142/354 (40%), Gaps = 63/354 (17%) Query: 154 EVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYG-SWFKEGADIPWDIPVATNTPSGKV 212 E PE VT + G V + C V++P T P Y WFK G IP I P V Sbjct: 28 EEPEFVTARAGESVVLRCDVIHPV---TGQPPPYVVEWFKFGVPIPIFIKFGYYPPH--V 82 Query: 213 QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT 272 + GR L + SL + R D G Y +V ++++ ++ VH+T + Sbjct: 83 DPEYAGRASL-----HDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLT-IN 136 Query: 273 HMPTFSI--PGTLES--GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSS 325 PTF+ P +E+ G +TC+ G P P +TW+ G + + Sbjct: 137 APPTFTETPPQYIEAKEGGSITMTCTA-----FGNPKPIVTWLKEGTLLGASGKYQVSDG 191 Query: 326 MLSLIPQPQDHGTSLTCQV-TLPGAGVTMTRAVRLN---ISYPPQNLTMTVFQGDGTAST 381 L++ ++ + TC+ ++ G V T + I PP+N+T+ + Sbjct: 192 SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNI--------- 242 Query: 382 TLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---------GVLE 432 Q L C ++ P L++TW + ++L G L Sbjct: 243 ------------SQDALLTCRAEAYP-GNLTYTWYWQDENVYFQNDLKLRVRILIDGTLI 289 Query: 433 LPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK---MRPISGVTLGAFG 483 + RV +D G++TC N LG + S S L +Y + M P+ V +G G Sbjct: 290 IFRVKPEDSGKYTCVPSNSLG-RSPSASAYLTVQYPARVLNMPPVIYVPVGIHG 342 >gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] Length = 1863 Score = 56.6 bits (135), Expect = 6e-08 Identities = 84/332 (25%), Positives = 117/332 (35%), Gaps = 51/332 (15%) Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215 P+S V+E V C V + +WF EG PV S +V ED Sbjct: 420 PQSQEVKENQTVKFRCEV-------SGIPKPEVAWFLEGT------PVRRQEGSIEVYED 466 Query: 216 THGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERG----SRKWNYIYDKLSVHVTAL 271 +L L AR DSG Y S W ++L+V A Sbjct: 467 AGSHYLCL------------LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 Query: 272 THMPTFSIPGTLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLS 328 + +E G L CSV +GTP P ITW+ G + T + + Sbjct: 515 SFSSVLKDCAVIE-GQDFVLQCSV-----RGTPVPRITWLLNGQPIQYARSTC-EAGVAE 567 Query: 329 LIPQ---PQDHGTSLTC--QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTL 383 L Q P+DHGT TC + L + V S + V TA L Sbjct: 568 LHIQDALPEDHGT-YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626 Query: 384 RNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVH 437 + S L V++G + + V NPP + W + S Q L + V Sbjct: 627 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686 Query: 438 VKDEGEFTCRAQNPLGSQHISLSLSLQNEYTG 469 +D G +TC A N G L++Q + G Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718 Score = 47.8 bits (112), Expect = 3e-05 Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 44/197 (22%) Query: 374 QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSP------SQSSN 427 + GTA + + V EG+ L L C V S+PPA + WT TL SQ + Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151 Query: 428 LGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGA 487 L + + + +D G + C A+N G S +++ + P S T Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD------APASENTKAP------ 1199 Query: 488 TALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH 547 ++S R KS+ P V G+ S + + PA +PP Sbjct: 1200 -------------EMKSRRPKSSLP-------------PVLGTESDATVKKKPAPKTPPK 1233 Query: 548 HAPPALATPSPEEGEIQ 564 A P PE+ +++ Sbjct: 1234 AAMPPQIIQFPEDQKVR 1250 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVHVKDEGEF 444 V EGQ C + P +++W G++ L PS + + + VLE+ V+ D G + Sbjct: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 Query: 445 TCRAQNPLGSQHISLSLSLQ 464 TC N G +S LS+Q Sbjct: 232 TCLVVNGSGKASMSAELSIQ 251 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 12/119 (10%) Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417 +L+ S+ Q + V + + S+ L++ +V+EGQ L C+V P R++W Sbjct: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKD---CAVIEGQDFVLQCSVRGTPVPRITWLLNG 551 Query: 418 LTLSPSQSS-NLGVLELPRVHV-----KDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470 + ++S+ GV EL H+ +D G +TC A+N LG S +++ + + + Sbjct: 552 QPIQYARSTCEAGVAEL---HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607 Score = 36.6 bits (83), Expect = 0.067 Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 8/100 (8%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSW-------TWGSLTLSPSQSSNLGVLELPRVHVKDE 441 L + EG + V P +++W T G L L + VH +D Sbjct: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 Query: 442 GEFTCRAQNPLGSQHISLSLSLQNEYTGKM-RPISGVTLG 480 G++TC A N G++ +++ L+++ + ++ +P+ TLG Sbjct: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141 Score = 34.7 bits (78), Expect = 0.26 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 20/140 (14%) Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392 P+D GT TC+ AG T+AV L + P DGT + +++ Sbjct: 687 PEDTGT-YTCEAW-NSAGEVRTQAV-LTVQEPH----------DGTQPWFISKPRSVTAS 733 Query: 393 EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS-------QSSNLGVLELPRVHVKDEGEFT 445 GQS+ + CA+ +P + W L Q+ ++ L L +V G++ Sbjct: 734 LGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYE 793 Query: 446 CRAQNPLGSQHISLSLSLQN 465 +N +G +SL LQN Sbjct: 794 ILLKNRVGECSCQVSLMLQN 813 Score = 30.4 bits (67), Expect = 4.8 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 380 STTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGV-------LE 432 S T+R+ L V+EG + C ++ P + W ++ S+ + L Sbjct: 1761 SKTIRD---LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817 Query: 433 LPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470 + V D+ ++TC+A N LG + L ++ G+ Sbjct: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855 >gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] Length = 1914 Score = 56.6 bits (135), Expect = 6e-08 Identities = 84/332 (25%), Positives = 117/332 (35%), Gaps = 51/332 (15%) Query: 156 PESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQED 215 P+S V+E V C V + +WF EG PV S +V ED Sbjct: 420 PQSQEVKENQTVKFRCEV-------SGIPKPEVAWFLEGT------PVRRQEGSIEVYED 466 Query: 216 THGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERG----SRKWNYIYDKLSVHVTAL 271 +L L AR DSG Y S W ++L+V A Sbjct: 467 AGSHYLCL------------LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 Query: 272 THMPTFSIPGTLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLS 328 + +E G L CSV +GTP P ITW+ G + T + + Sbjct: 515 SFSSVLKDCAVIE-GQDFVLQCSV-----RGTPVPRITWLLNGQPIQYARSTC-EAGVAE 567 Query: 329 LIPQ---PQDHGTSLTC--QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTL 383 L Q P+DHGT TC + L + V S + V TA L Sbjct: 568 LHIQDALPEDHGT-YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626 Query: 384 RNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVH 437 + S L V++G + + V NPP + W + S Q L + V Sbjct: 627 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686 Query: 438 VKDEGEFTCRAQNPLGSQHISLSLSLQNEYTG 469 +D G +TC A N G L++Q + G Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718 Score = 47.8 bits (112), Expect = 3e-05 Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 44/197 (22%) Query: 374 QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSP------SQSSN 427 + GTA + + V EG+ L L C V S+PPA + WT TL SQ + Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151 Query: 428 LGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGA 487 L + + + +D G + C A+N G S +++ + P S T Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD------APASENTKAP------ 1199 Query: 488 TALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH 547 ++S R KS+ P V G+ S + + PA +PP Sbjct: 1200 -------------EMKSRRPKSSLP-------------PVLGTESDATVKKKPAPKTPPK 1233 Query: 548 HAPPALATPSPEEGEIQ 564 A P PE+ +++ Sbjct: 1234 AAMPPQIIQFPEDQKVR 1250 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS------QSSNLGVLELPRVHVKDEGEF 444 V EGQ C + P +++W G++ L PS + + + VLE+ V+ D G + Sbjct: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 Query: 445 TCRAQNPLGSQHISLSLSLQ 464 TC N G +S LS+Q Sbjct: 232 TCLVVNGSGKASMSAELSIQ 251 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 12/119 (10%) Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417 +L+ S+ Q + V + + S+ L++ +V+EGQ L C+V P R++W Sbjct: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKD---CAVIEGQDFVLQCSVRGTPVPRITWLLNG 551 Query: 418 LTLSPSQSS-NLGVLELPRVHV-----KDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470 + ++S+ GV EL H+ +D G +TC A+N LG S +++ + + + Sbjct: 552 QPIQYARSTCEAGVAEL---HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607 Score = 36.6 bits (83), Expect = 0.067 Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 8/100 (8%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSW-------TWGSLTLSPSQSSNLGVLELPRVHVKDE 441 L + EG + V P +++W T G L L + VH +D Sbjct: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 Query: 442 GEFTCRAQNPLGSQHISLSLSLQNEYTGKM-RPISGVTLG 480 G++TC A N G++ +++ L+++ + ++ +P+ TLG Sbjct: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141 Score = 34.7 bits (78), Expect = 0.26 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 20/140 (14%) Query: 333 PQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVL 392 P+D GT TC+ AG T+AV L + P DGT + +++ Sbjct: 687 PEDTGT-YTCEAW-NSAGEVRTQAV-LTVQEPH----------DGTQPWFISKPRSVTAS 733 Query: 393 EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS-------QSSNLGVLELPRVHVKDEGEFT 445 GQS+ + CA+ +P + W L Q+ ++ L L +V G++ Sbjct: 734 LGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYE 793 Query: 446 CRAQNPLGSQHISLSLSLQN 465 +N +G +SL LQN Sbjct: 794 ILLKNRVGECSCQVSLMLQN 813 Score = 30.4 bits (67), Expect = 4.8 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 380 STTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGV-------LE 432 S T+R+ L V+EG + C ++ P + W ++ S+ + L Sbjct: 1812 SKTIRD---LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 Query: 433 LPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGK 470 + V D+ ++TC+A N LG + L ++ G+ Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 >gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens] Length = 328 Score = 55.8 bits (133), Expect = 1e-07 Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 35/218 (16%) Query: 139 VNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIP 198 +N R+ ++VP V+ + G +PC+ +PH ++ P+ W A P Sbjct: 32 LNTEVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHPHRHY--DGPLTAIW---RAGEP 86 Query: 199 WDIPVATNTPSGKVQE------DTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVER 252 + P + + E HGRF LLG+P+ N+ SL + D +Y+ +VE Sbjct: 87 YAGPQVFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEF 146 Query: 253 GSRKWNYIYDK------LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPT 306 ++D+ + +HVTA + S+ H C+ E PP Sbjct: 147 AGD----VHDRYESRHGVRLHVTAAPRIVNISV--LPSPAHAFRALCT----AEGEPPPA 196 Query: 307 ITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQV 344 + W G ++ +S+ ++ + HG +T ++ Sbjct: 197 LAWSGPALG--------NSLAAVRSPREGHGHLVTAEL 226 Score = 33.1 bits (74), Expect = 0.74 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 19/125 (15%) Query: 378 TASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSL------TLSPSQS-SNLGV 430 TA+ + N S L + +C + PP L+W+ +L SP + +L Sbjct: 165 TAAPRIVNISVLPS-PAHAFRALCTAEGEPPPALAWSGPALGNSLAAVRSPREGHGHLVT 223 Query: 431 LELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGA--FGGAGAT 488 ELP + +G +TC A N LG S+ Y + SG + A G G Sbjct: 224 AELPA--LTHDGRYTCTAANSLGRSEASV-------YLFRFHGASGASTVALLLGALGFK 274 Query: 489 ALVFL 493 AL+ L Sbjct: 275 ALLLL 279 >gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3874 Score = 55.1 bits (131), Expect = 2e-07 Identities = 65/237 (27%), Positives = 86/237 (36%), Gaps = 43/237 (18%) Query: 233 LSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLE----SGHP 288 L I++A+ D G Y +V N + + + PTF P T +G P Sbjct: 1897 LEIQEAQVSDKGLYSCKVS------NVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP 1950 Query: 289 RNLTCSVPWACEQGTP-PTITW----MGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTC 342 LTC V G P PT+TW M S++ ++R L L QP GT TC Sbjct: 1951 LVLTCDV-----SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTC 2004 Query: 343 QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402 A V + L + G A VLEGQ + L C Sbjct: 2005 VAENTQAEARKDFVVAV--------LVAPRIRSSGVAREH-------HVLEGQEVRLDCE 2049 Query: 403 VDSNPPARLSWTWGSLTLSPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLG 453 D PP ++W L +L G L L + D G +TC A NP G Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2106 Score = 48.9 bits (115), Expect = 1e-05 Identities = 104/458 (22%), Positives = 169/458 (36%), Gaps = 96/458 (20%) Query: 28 MQKSVTVQEGLCVSVLCSFS-YPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQ 86 +++ + V +G ++C+ + +PQ T WF+ G ++R Sbjct: 1260 LEEVIKVLDGQTAHLMCNVTGHPQPKLT--------WFKDGRPLARG------------- 1298 Query: 87 EETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQD 146 D H+ D L + S AG Y C+ + K+ QLSV + + Sbjct: 1299 ----DAHHISPD----GVLLQVLQANLSSAGHYS-CIAANAVGEKTKHFQLSVLLAPT-- 1347 Query: 147 LLSRYRLEVPESVTVQEGLCVSVPCSVL-YPHYNWTASSPVYGSWFKEGADIPWDIPVAT 205 +L E VTV +S+ C L +P N T W K+GA P++ Sbjct: 1348 ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNIT--------WMKDGA--PFEASRNI 1397 Query: 206 NTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDK 263 G THG L I +A+K D+G+Y V E G NY + Sbjct: 1398 QLLPG-----THG--------------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1438 Query: 264 LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITW----MGASVSSLDP 319 L +++ G E N T ++ PPTI W + SS Sbjct: 1439 LIP--PSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 1496 Query: 320 TITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQ--GD 376 + +L + P Q D G L + G + + I PP +FQ GD Sbjct: 1497 VLGEGRLLQIQPTQVSDSGRYLCVATNVAGED---DQDFNVLIQVPP------MFQKVGD 1547 Query: 377 GTASTTL-------RNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN 427 +A+ + R G ++E +L C ++ PP L+W LS + Sbjct: 1548 FSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVS 1607 Query: 428 L----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSL 461 + VL++P V ++ G ++C+A N +G + L Sbjct: 1608 VLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 1645 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 18/111 (16%) Query: 359 LNISYPPQNLTMTVFQG-DGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417 +N+ PP T+ QG DG+ + R G ++ +VC V +PP +SW Sbjct: 2114 VNVLVPP-----TIKQGADGSGTLVSRPGELVT--------MVCPVRGSPPIHVSWLKDG 2160 Query: 418 LTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 L L SQ + L L + +V + D G FTC A +P G + +L +Q Sbjct: 2161 LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2211 Score = 44.7 bits (104), Expect = 2e-04 Identities = 62/243 (25%), Positives = 93/243 (38%), Gaps = 39/243 (16%) Query: 233 LSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRN 290 L I A+ D+G Y GS + Y L V+V +P S+PG + P Sbjct: 750 LRIEQAQLSDAGSYRCVASNVAGSTELRY---GLRVNVPPRITLPP-SLPGPVLVNTPVR 805 Query: 291 LTCSVPWACEQGTPPTITWM--GASVSSLDP----TITRSSMLSLIPQPQDHGTSLTCQV 344 LTC+ A PT+ W+ G VS +L+L +C V Sbjct: 806 LTCNATGA----PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC-V 860 Query: 345 TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404 + G V L + PP + L +SV+ +S+ L C Sbjct: 861 AVSAVGEDRQDVV-LQVHMPP---------------SILGEELNVSVVANESVALECQSH 904 Query: 405 SNPPARLSWTWGSLTLSPSQ----SSNLGVLELPRVHVKDEGEFTCRAQNPLG--SQHIS 458 + PP LSW L P S++ +L++ R V D G +TC A N G +H + Sbjct: 905 AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYN 964 Query: 459 LSL 461 L++ Sbjct: 965 LNV 967 Score = 44.3 bits (103), Expect = 3e-04 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 41/263 (15%) Query: 222 LLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDKLSVHVTALTHMPTFSI 279 LL SL + GDSG Y E G + ++ + V H+ Sbjct: 2256 LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF-----QLTVMEPPHIEDSGQ 2310 Query: 280 PG--TLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLSLIPQPQ 334 P +L G P L C QGTP P ITW G +++ L+ +S + + + + Sbjct: 2311 PTELSLTPGAPMELLCDA-----QGTPQPNITWHKDGQALTRLE----NNSRATRVLRVR 2361 Query: 335 DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394 D G TC P + ++ R+ + PP + G G A G Sbjct: 2362 DAGL-YTCLAESPAGAIE--KSFRVRVQAPPNIV--------GPRGPRFVVGLA----PG 2406 Query: 395 QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEFTCRAQN 450 Q L L C+V++ P +++W + L + L+L + D G+++C A+N Sbjct: 2407 Q-LVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 2465 Query: 451 PLGSQHISLSLSLQNEYTGKMRP 473 GS ++ + + T + P Sbjct: 2466 AAGSTSVAFRVEIHTVPTIRSGP 2488 Score = 42.4 bits (98), Expect = 0.001 Identities = 69/294 (23%), Positives = 111/294 (37%), Gaps = 62/294 (21%) Query: 189 SWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYF 248 +WFK+GA +P S KV GR L LG Q+++ + A Sbjct: 344 TWFKDGALLP---------TSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA---- 390 Query: 249 QVERGSRKWNYIYDKLSVHVTALTHMPTFSIPG------TLESGHPRNLTCSVPWACEQG 302 E+ +R L V+V PT G +G P L C +G Sbjct: 391 -AEKATR--------LDVYVP-----PTIEGAGGRPYVVKAVAGRPVALECVA-----RG 431 Query: 303 TP-PTITW----MGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357 P PT++W + + S+ T S+L L + +C + P + +V Sbjct: 432 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV 491 Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWG- 416 + + PPQ L V +G G +T + GQ L L C +P + W Sbjct: 492 EVQV--PPQLL---VAEGLGQVTTIV----------GQPLELPCQASGSPVPTIQWLQNG 536 Query: 417 --SLTLSPSQSSNLG-VLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEY 467 + L+ Q ++ G L + V + G F C+A N G+ + +S+ E+ Sbjct: 537 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEW 590 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 6/81 (7%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEF 444 + VL+GQ+ HL+C V +P +L+W L+ + ++ +L++ + ++ G + Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1323 Query: 445 TCRAQNPLG--SQHISLSLSL 463 +C A N +G ++H LS+ L Sbjct: 1324 SCIAANAVGEKTKHFQLSVLL 1344 Score = 42.4 bits (98), Expect = 0.001 Identities = 63/217 (29%), Positives = 89/217 (41%), Gaps = 37/217 (17%) Query: 279 IPGTLESGHPRNLTCSVPWA---CE-QGTP-PTITWM--GASVSSLDPTITRSSMLSLIP 331 +P +E+G P T A C+ +G+P P ITW G VS + T L+ Sbjct: 2845 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 2904 Query: 332 ---QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388 + QD GT TC T A R V L I L + VF TTL + Sbjct: 2905 KNLEGQDAGT-YTC--TAENAVGRARRRVHLTI------LVLPVF-------TTLPGDRS 2948 Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV--KDEGEFTC 446 L + G L L CA +P R+ WT ++ S G L R V +D G + C Sbjct: 2949 LRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC 3006 Query: 447 RAQNPLGSQ------HISLSLSLQNE-YTGKMRPISG 476 A+N +G H+ + LQ E ++ + P+ G Sbjct: 3007 WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 3043 Score = 38.9 bits (89), Expect = 0.014 Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 56/298 (18%) Query: 180 WTASSPV-YGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 238 WT+ P W K+ PV P +VQED L I + Sbjct: 240 WTSGVPTPQVEWTKDRQ------PVLPGGPHLQVQEDGQ--------------VLRITGS 279 Query: 239 RKGDSGKYYFQVERGSRKWNYIYD-KLSVHVTALTHMPTFSIPGTLESGHPRNLTCS-VP 296 GD G+Y Q S D +L VH PT I G+ E+G + V Sbjct: 280 HVGDEGRY--QCVAFSPAGQQARDFQLRVHAP-----PT--IWGSNETGEVAVMEDHLVQ 330 Query: 297 WACE-QGTP-PTITWM--GASV-SSLDPTITRSSMLSLIPQPQDHGTSL-TCQVTLPGAG 350 CE +G P P ITW GA + +S TR + + Q + TC+ + A Sbjct: 331 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS--NAV 388 Query: 351 VTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPAR 410 +A RL++ PP +G G ++ + G+ + L C +P Sbjct: 389 GAAEKATRLDVYVPP------TIEGAGGRPYVVK------AVAGRPVALECVARGHPSPT 436 Query: 411 LSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 LSW L ++ S S L VL L G ++C A +P G + S+ +Q Sbjct: 437 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 494 Score = 38.9 bits (89), Expect = 0.014 Identities = 80/383 (20%), Positives = 131/383 (34%), Gaps = 75/383 (19%) Query: 120 VFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL----CVSVPCSVLY 175 V +E+ + Y ++ NV S +L R+ VP +T+ L V+ P + Sbjct: 749 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 808 Query: 176 PHYNWTASSPVYGSWFKEGADI-PWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLS 234 N T + W K+G + P P P G+V L+ Sbjct: 809 ---NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV--------------------LT 845 Query: 235 IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCS 294 + AR DSG+Y + D+ V + HMP + L N + + Sbjct: 846 LASARASDSGRYSCVAVSAVGE-----DRQDVVLQV--HMPPSILGEELNVSVVANESVA 898 Query: 295 VPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGV--- 351 + PP ++W L P+P H ++ + + A V Sbjct: 899 LECQSHAMPPPVLSWW-------------KDGRPLEPRPGVHLSADKALLQVDRADVWDA 945 Query: 352 ------TMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDS 405 + +A R Y VF LR L+V EG L C Sbjct: 946 GHYTCEALNQAGRSEKHYNLNVWVAPVFP--------LRESHTLTVREGHPTSLSCECRG 997 Query: 406 NPPARLSWTWGSLTLSPSQSSNLG-------VLELPRVHVKDEGEFTCRAQNPLG--SQH 456 P ++SW L P + + L +L L + + EG +TC N +G SQ Sbjct: 998 VPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQD 1056 Query: 457 ISLSLSLQNEYTGKMRPISGVTL 479 + L + + + G P + V++ Sbjct: 1057 LQLEVHVPPQIAGPREPPTQVSV 1079 Score = 36.6 bits (83), Expect = 0.067 Identities = 43/188 (22%), Positives = 66/188 (35%), Gaps = 19/188 (10%) Query: 286 GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLD--PTITRSSMLSLIPQPQDHGTSL 340 G P L C G+P PTI W+ G L ++ + L + DH Sbjct: 513 GQPLELPCQA-----SGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLF 567 Query: 341 TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 400 CQ T V ++ + P L + + G + S+ +H Sbjct: 568 ACQATNEAGTAGAEVEVSVHGEWAPGVLEVPI----GQYHWGXEHHSSFPAACDPPVHRG 623 Query: 401 CAVDSNPPARLSWT-----WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455 PP W WG T P S L++ +V ++DEG +TC A N G Sbjct: 624 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 683 Query: 456 HISLSLSL 463 ++L + Sbjct: 684 KREVALKV 691 Score = 36.2 bits (82), Expect = 0.088 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWG----SLTLSPSQSSNLGVLELPRVHVKDEGEFT 445 +VLE S+ L C PP +SW G S + + S + VL + + + D G + Sbjct: 705 AVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 764 Query: 446 CRAQNPLGSQHISLSL 461 C A N GS + L Sbjct: 765 CVASNVAGSTELRYGL 780 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 3/95 (3%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFT 445 ++V G + L C P + W L S+ G L L V D G + Sbjct: 3127 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 3186 Query: 446 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480 C A N LGS L ++ E G ++GV G Sbjct: 3187 CVAHNLLGSATARAFLVVRGEPQGSWGSMTGVING 3221 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444 ++V ++ L C NP +SW L SPS + VL++ V D + Sbjct: 1664 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASY 1723 Query: 445 TCRAQNPLGSQHISLSLSLQ 464 C A+N GS +L +Q Sbjct: 1724 MCVAENQAGSAEKLFTLRVQ 1743 Score = 34.7 bits (78), Expect = 0.26 Identities = 46/213 (21%), Positives = 80/213 (37%), Gaps = 38/213 (17%) Query: 282 TLESGHPRNLTCSVPWACEQGTP-PTITWM---------GASVSSLDPTITRSSMLSLIP 331 T+ GHP +L+C +G P P I+W GA + + + R L Sbjct: 982 TVREGHPTSLSCEC-----RGVPFPKISWRKDGQPLPGEGAGLQHVS-AVGRLLYLGQAQ 1035 Query: 332 QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSV 391 Q+ + C + + ++ ++L + PPQ G T +SV Sbjct: 1036 LAQEGTYTCECSNVVGNS----SQDLQLEVHVPPQ------IAGPREPPT------QVSV 1079 Query: 392 LEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---QSSNLG-VLELPRVHVKDEGEFTCR 447 ++ L C PP ++W + Q N G L + R G ++C Sbjct: 1080 VQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCV 1139 Query: 448 AQNPLG--SQHISLSLSLQNEYTGKMRPISGVT 478 A+N G + LS+ + E G + P++ +T Sbjct: 1140 AENLAGRAERKFELSVLVPPELIGDLDPLTNIT 1172 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444 ++ + S+ L C V ++P ++W S LS + L L+L R + D G + Sbjct: 1756 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMY 1815 Query: 445 TCRAQNPLGSQHISLSLSL 463 TC A N G + LS+ Sbjct: 1816 TCEALNAAGRDQKLVQLSV 1834 Score = 33.9 bits (76), Expect = 0.44 Identities = 43/185 (23%), Positives = 67/185 (36%), Gaps = 30/185 (16%) Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360 +G P +WMG +VS +D + R L D G S C + + +R+N Sbjct: 730 KGHQPVSSWMGVTVS-VDGRVLRIEQAQL----SDAG-SYRCVASNVAGSTELRYGLRVN 783 Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420 + PP+ TL VL + L C P L W + Sbjct: 784 V--PPR--------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPV 827 Query: 421 SPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLGS--QHISLSLSLQNEYTGKMR 472 SP+ + L VL L D G ++C A + +G Q + L + + G+ Sbjct: 828 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEEL 887 Query: 473 PISGV 477 +S V Sbjct: 888 NVSVV 892 Score = 33.9 bits (76), Expect = 0.44 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 369 TMTVFQGDGTASTTLRNGS-ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---- 423 T F+ + T+R+G A++V Q+ L C D P +SW + L P Sbjct: 2470 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529 Query: 424 QSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 + G L + V +D G + C A N GS Sbjct: 2530 EILPEGSLRIQPVLAQDAGHYLCLASNSAGS 2560 Score = 33.5 bits (75), Expect = 0.57 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 397 LHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPL 452 L L+C PP + W G +SP + + L +L++ + +D G ++C A N Sbjct: 1179 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1238 Query: 453 GSQHISLSL------SLQNE 466 G + S+ S++NE Sbjct: 1239 GEARRNFSVEVLVPPSIENE 1258 Score = 33.1 bits (74), Expect = 0.74 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 386 GSALSVLE---GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVK 439 G A S L G S+ L C V +P + W L L S + G L + R Sbjct: 3031 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 3090 Query: 440 DEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRP 473 D G + C A+N +G + L LQ+ ++ P Sbjct: 3091 DAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 3124 Score = 32.7 bits (73), Expect = 0.97 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 381 TTLRNGSALSVL--EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS----QSSNLG-VLEL 433 + L G+A VL G + L C P ++ WT + P Q G VL + Sbjct: 217 SVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRI 276 Query: 434 PRVHVKDEGEFTCRAQNPLGSQ 455 HV DEG + C A +P G Q Sbjct: 277 TGSHVGDEGRYQCVAFSPAGQQ 298 Score = 29.6 bits (65), Expect = 8.2 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGE 443 A+ V G L C D+ P ++W L +Q + LE+ V D+G Sbjct: 1850 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 1909 Query: 444 FTCRAQNPLGSQHISLSLSLQ 464 ++C+ N G + +L++Q Sbjct: 1910 YSCKVSNVAGEAVRTFTLTVQ 1930 >gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] Length = 5065 Score = 55.1 bits (131), Expect = 2e-07 Identities = 65/237 (27%), Positives = 86/237 (36%), Gaps = 43/237 (18%) Query: 233 LSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLE----SGHP 288 L I++A+ D G Y +V N + + + PTF P T +G P Sbjct: 3088 LEIQEAQVSDKGLYSCKVS------NVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP 3141 Query: 289 RNLTCSVPWACEQGTP-PTITW----MGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTC 342 LTC V G P PT+TW M S++ ++R L L QP GT TC Sbjct: 3142 LVLTCDV-----SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTC 3195 Query: 343 QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402 A V + L + G A VLEGQ + L C Sbjct: 3196 VAENTQAEARKDFVVAV--------LVAPRIRSSGVAREH-------HVLEGQEVRLDCE 3240 Query: 403 VDSNPPARLSWTWGSLTLSPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLG 453 D PP ++W L +L G L L + D G +TC A NP G Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 3297 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 5/97 (5%) Query: 369 TMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLT--LSPSQSS 426 T+T++ D + + + + + V G+ LVC PP R+ W G L L+P SS Sbjct: 689 TVTLYYTDPPSVSAVN--AVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSS 746 Query: 427 NLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463 + G L +P +D G +TCRA N LG + L++ Sbjct: 747 S-GKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782 Score = 48.9 bits (115), Expect = 1e-05 Identities = 104/458 (22%), Positives = 169/458 (36%), Gaps = 96/458 (20%) Query: 28 MQKSVTVQEGLCVSVLCSFS-YPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQ 86 +++ + V +G ++C+ + +PQ T WF+ G ++R Sbjct: 2451 LEEVIKVLDGQTAHLMCNVTGHPQPKLT--------WFKDGRPLARG------------- 2489 Query: 87 EETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQD 146 D H+ D L + S AG Y C+ + K+ QLSV + + Sbjct: 2490 ----DAHHISPD----GVLLQVLQANLSSAGHYS-CIAANAVGEKTKHFQLSVLLAPT-- 2538 Query: 147 LLSRYRLEVPESVTVQEGLCVSVPCSVL-YPHYNWTASSPVYGSWFKEGADIPWDIPVAT 205 +L E VTV +S+ C L +P N T W K+GA P++ Sbjct: 2539 ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNIT--------WMKDGA--PFEASRNI 2588 Query: 206 NTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDK 263 G THG L I +A+K D+G+Y V E G NY + Sbjct: 2589 QLLPG-----THG--------------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 2629 Query: 264 LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITW----MGASVSSLDP 319 L +++ G E N T ++ PPTI W + SS Sbjct: 2630 LIP--PSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 2687 Query: 320 TITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQ--GD 376 + +L + P Q D G L + G + + I PP +FQ GD Sbjct: 2688 VLGEGRLLQIQPTQVSDSGRYLCVATNVAGED---DQDFNVLIQVPP------MFQKVGD 2738 Query: 377 GTASTTL-------RNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN 427 +A+ + R G ++E +L C ++ PP L+W LS + Sbjct: 2739 FSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVS 2798 Query: 428 L----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSL 461 + VL++P V ++ G ++C+A N +G + L Sbjct: 2799 VLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 2836 Score = 47.8 bits (112), Expect = 3e-05 Identities = 100/408 (24%), Positives = 145/408 (35%), Gaps = 93/408 (22%) Query: 101 NKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTA-SQDLLSRYRLEVPESV 159 +K+ TL I DAG YV C + ++ + +LSVN A S+ + Y L S+ Sbjct: 1026 SKEGTLLIAQPSAQDAGAYV-CTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSL 1084 Query: 160 TVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKE--GADIPWDIP--------------- 202 + + V V S HY TAS+P + + G +P + Sbjct: 1085 RLAQ---VQVGDS---GHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALD 1138 Query: 203 ---VATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVER--GSRKW 257 VA P ++ G L PQ S+ R D+G+Y + G W Sbjct: 1139 LNCVAEGNPEPQLSWSKDGVVLQGRGPQG---SVHFAAIRTSDAGRYRCEASNSAGVDAW 1195 Query: 258 NYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTP-PTITWM-GASVS 315 ++ + V H G LE N + P +GTP P +TW G S Sbjct: 1196 -----EVELRVLEPPHWGADETSGLLERVAGENASLPCP---ARGTPKPQVTWRKGPSSE 1247 Query: 316 SLD-----PTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTM 370 L + S+ P D G CQ T G T RA +L + PP Sbjct: 1248 PLHGQPGVAVLEEGSLFLASVSPADSG-DYECQATNE-VGSTSRRA-KLVVYVPPS---- 1300 Query: 371 TVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT---------------- 414 + DG + +S + GQSL L C + P + W Sbjct: 1301 --IREDGRKAN-------VSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYG 1351 Query: 415 ----WGSL----TLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 WG + L QS L PR+ D G ++CRA+N G+ Sbjct: 1352 WDLGWGQVGGHRLLDEGQS-----LHFPRIQEGDSGLYSCRAENQAGT 1394 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 18/111 (16%) Query: 359 LNISYPPQNLTMTVFQG-DGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417 +N+ PP T+ QG DG+ + R G ++ +VC V +PP +SW Sbjct: 3305 VNVLVPP-----TIKQGADGSGTLVSRPGELVT--------MVCPVRGSPPIHVSWLKDG 3351 Query: 418 LTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 L L SQ + L L + +V + D G FTC A +P G + +L +Q Sbjct: 3352 LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 3402 Score = 44.7 bits (104), Expect = 2e-04 Identities = 62/243 (25%), Positives = 93/243 (38%), Gaps = 39/243 (16%) Query: 233 LSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRN 290 L I A+ D+G Y GS + Y L V+V +P S+PG + P Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRY---GLRVNVPPRITLPP-SLPGPVLVNTPVR 1996 Query: 291 LTCSVPWACEQGTPPTITWM--GASVSSLDP----TITRSSMLSLIPQPQDHGTSLTCQV 344 LTC+ A PT+ W+ G VS +L+L +C V Sbjct: 1997 LTCNATGA----PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC-V 2051 Query: 345 TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404 + G V L + PP + L +SV+ +S+ L C Sbjct: 2052 AVSAVGEDRQDVV-LQVHMPP---------------SILGEELNVSVVANESVALECQSH 2095 Query: 405 SNPPARLSWTWGSLTLSPSQ----SSNLGVLELPRVHVKDEGEFTCRAQNPLG--SQHIS 458 + PP LSW L P S++ +L++ R V D G +TC A N G +H + Sbjct: 2096 AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYN 2155 Query: 459 LSL 461 L++ Sbjct: 2156 LNV 2158 Score = 44.3 bits (103), Expect = 3e-04 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 41/263 (15%) Query: 222 LLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDKLSVHVTALTHMPTFSI 279 LL SL + GDSG Y E G + ++ + V H+ Sbjct: 3447 LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF-----QLTVMEPPHIEDSGQ 3501 Query: 280 PG--TLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLSLIPQPQ 334 P +L G P L C QGTP P ITW G +++ L+ +S + + + + Sbjct: 3502 PTELSLTPGAPMELLCDA-----QGTPQPNITWHKDGQALTRLE----NNSRATRVLRVR 3552 Query: 335 DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394 D G TC P + ++ R+ + PP + G G A G Sbjct: 3553 DAGL-YTCLAESPAGAIE--KSFRVRVQAPPNIV--------GPRGPRFVVGLA----PG 3597 Query: 395 QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEFTCRAQN 450 Q L L C+V++ P +++W + L + L+L + D G+++C A+N Sbjct: 3598 Q-LVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 3656 Query: 451 PLGSQHISLSLSLQNEYTGKMRP 473 GS ++ + + T + P Sbjct: 3657 AAGSTSVAFRVEIHTVPTIRSGP 3679 Score = 42.4 bits (98), Expect = 0.001 Identities = 69/294 (23%), Positives = 111/294 (37%), Gaps = 62/294 (21%) Query: 189 SWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYF 248 +WFK+GA +P S KV GR L LG Q+++ + A Sbjct: 1535 TWFKDGALLP---------TSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA---- 1581 Query: 249 QVERGSRKWNYIYDKLSVHVTALTHMPTFSIPG------TLESGHPRNLTCSVPWACEQG 302 E+ +R L V+V PT G +G P L C +G Sbjct: 1582 -AEKATR--------LDVYVP-----PTIEGAGGRPYVVKAVAGRPVALECVA-----RG 1622 Query: 303 TP-PTITW----MGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357 P PT++W + + S+ T S+L L + +C + P + +V Sbjct: 1623 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV 1682 Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWG- 416 + + PPQ L V +G G +T + GQ L L C +P + W Sbjct: 1683 EVQV--PPQLL---VAEGLGQVTTIV----------GQPLELPCQASGSPVPTIQWLQNG 1727 Query: 417 --SLTLSPSQSSNLG-VLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEY 467 + L+ Q ++ G L + V + G F C+A N G+ + +S+ E+ Sbjct: 1728 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEW 1781 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 6/81 (7%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEF 444 + VL+GQ+ HL+C V +P +L+W L+ + ++ +L++ + ++ G + Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 2514 Query: 445 TCRAQNPLG--SQHISLSLSL 463 +C A N +G ++H LS+ L Sbjct: 2515 SCIAANAVGEKTKHFQLSVLL 2535 Score = 42.4 bits (98), Expect = 0.001 Identities = 63/217 (29%), Positives = 89/217 (41%), Gaps = 37/217 (17%) Query: 279 IPGTLESGHPRNLTCSVPWA---CE-QGTP-PTITWM--GASVSSLDPTITRSSMLSLIP 331 +P +E+G P T A C+ +G+P P ITW G VS + T L+ Sbjct: 4036 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 4095 Query: 332 ---QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388 + QD GT TC T A R V L I L + VF TTL + Sbjct: 4096 KNLEGQDAGT-YTC--TAENAVGRARRRVHLTI------LVLPVF-------TTLPGDRS 4139 Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV--KDEGEFTC 446 L + G L L CA +P R+ WT ++ S G L R V +D G + C Sbjct: 4140 LRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC 4197 Query: 447 RAQNPLGSQ------HISLSLSLQNE-YTGKMRPISG 476 A+N +G H+ + LQ E ++ + P+ G Sbjct: 4198 WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 4234 Score = 40.8 bits (94), Expect = 0.004 Identities = 65/278 (23%), Positives = 98/278 (35%), Gaps = 42/278 (15%) Query: 204 ATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDK 263 A+ P +V G ++L +++ L I A++ D+G Y R N + D Sbjct: 721 ASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYT------CRAVNELGDA 774 Query: 264 LSVHVTALTHMPTFS-IPG--TLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPT 320 + A+ H P + +P T+E G L C PPT+TW L Sbjct: 775 SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGR----PPPTVTWRRGDGQPLGLR 830 Query: 321 ITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAS 380 + G + P +GV +V P VF + Sbjct: 831 L---------------GAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 875 Query: 381 TTLRNGSA----------LSVLEGQSLHLVCAVDSNPPA-RLSWTWGSLTLSPSQSSNL- 428 + G A + VLEGQ + L C V + P W L P ++ Sbjct: 876 RLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIR 935 Query: 429 --GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 G L L R + G ++C A N GSQH + L +Q Sbjct: 936 ADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 973 Score = 38.9 bits (89), Expect = 0.014 Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 56/298 (18%) Query: 180 WTASSPV-YGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 238 WT+ P W K+ PV P +VQED L I + Sbjct: 1431 WTSGVPTPQVEWTKDRQ------PVLPGGPHLQVQEDGQ--------------VLRITGS 1470 Query: 239 RKGDSGKYYFQVERGSRKWNYIYD-KLSVHVTALTHMPTFSIPGTLESGHPRNLTCS-VP 296 GD G+Y Q S D +L VH PT I G+ E+G + V Sbjct: 1471 HVGDEGRY--QCVAFSPAGQQARDFQLRVHAP-----PT--IWGSNETGEVAVMEDHLVQ 1521 Query: 297 WACE-QGTP-PTITWM--GASV-SSLDPTITRSSMLSLIPQPQDHGTSL-TCQVTLPGAG 350 CE +G P P ITW GA + +S TR + + Q + TC+ + A Sbjct: 1522 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS--NAV 1579 Query: 351 VTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPAR 410 +A RL++ PP +G G ++ + G+ + L C +P Sbjct: 1580 GAAEKATRLDVYVPP------TIEGAGGRPYVVK------AVAGRPVALECVARGHPSPT 1627 Query: 411 LSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 LSW L ++ S S L VL L G ++C A +P G + S+ +Q Sbjct: 1628 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 1685 Score = 38.5 bits (88), Expect = 0.018 Identities = 80/380 (21%), Positives = 131/380 (34%), Gaps = 69/380 (18%) Query: 120 VFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL----CVSVPCSVLY 175 V +E+ + Y ++ NV S +L R+ VP +T+ L V+ P + Sbjct: 1940 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 1999 Query: 176 PHYNWTASSPVYGSWFKEGADI-PWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLS 234 N T + W K+G + P P P G+V L+ Sbjct: 2000 ---NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV--------------------LT 2036 Query: 235 IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCS 294 + AR DSG+Y + D+ V + HMP + L N + + Sbjct: 2037 LASARASDSGRYSCVAVSAVGE-----DRQDVVLQV--HMPPSILGEELNVSVVANESVA 2089 Query: 295 VPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGV--- 351 + PP ++W L P+P H ++ + + A V Sbjct: 2090 LECQSHAMPPPVLSWW-------------KDGRPLEPRPGVHLSADKALLQVDRADVWDA 2136 Query: 352 ---TMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPP 408 T + S NL + V LR L+V EG L C P Sbjct: 2137 GHYTCEALNQAGHSEKHYNLNVWV-----APVFPLRESHTLTVREGHPTSLSCECRGVPF 2191 Query: 409 ARLSWTWGSLTLSPSQSSNLG-------VLELPRVHVKDEGEFTCRAQNPLG--SQHISL 459 ++SW L P + + L +L L + + EG +TC N +G SQ + L Sbjct: 2192 PKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQL 2250 Query: 460 SLSLQNEYTGKMRPISGVTL 479 + + + G P + V++ Sbjct: 2251 EVHVPPQIAGPREPPTQVSV 2270 Score = 36.6 bits (83), Expect = 0.067 Identities = 43/188 (22%), Positives = 66/188 (35%), Gaps = 19/188 (10%) Query: 286 GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLD--PTITRSSMLSLIPQPQDHGTSL 340 G P L C G+P PTI W+ G L ++ + L + DH Sbjct: 1704 GQPLELPCQA-----SGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLF 1758 Query: 341 TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 400 CQ T V ++ + P L + + G + S+ +H Sbjct: 1759 ACQATNEAGTAGAEVEVSVHGEWAPGVLEVPI----GQYHWGXEHHSSFPAACDPPVHRG 1814 Query: 401 CAVDSNPPARLSWT-----WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455 PP W WG T P S L++ +V ++DEG +TC A N G Sbjct: 1815 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 1874 Query: 456 HISLSLSL 463 ++L + Sbjct: 1875 KREVALKV 1882 Score = 36.2 bits (82), Expect = 0.088 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWG----SLTLSPSQSSNLGVLELPRVHVKDEGEFT 445 +VLE S+ L C PP +SW G S + + S + VL + + + D G + Sbjct: 1896 AVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 1955 Query: 446 CRAQNPLGSQHISLSL 461 C A N GS + L Sbjct: 1956 CVASNVAGSTELRYGL 1971 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 3/95 (3%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFT 445 ++V G + L C P + W L S+ G L L V D G + Sbjct: 4318 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 4377 Query: 446 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480 C A N LGS L ++ E G ++GV G Sbjct: 4378 CVAHNLLGSATARAFLVVRGEPQGSWGSMTGVING 4412 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444 ++V ++ L C NP +SW L SPS + VL++ V D + Sbjct: 2855 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASY 2914 Query: 445 TCRAQNPLGSQHISLSLSLQ 464 C A+N GS +L +Q Sbjct: 2915 MCVAENQAGSAEKLFTLRVQ 2934 Score = 34.7 bits (78), Expect = 0.26 Identities = 46/213 (21%), Positives = 80/213 (37%), Gaps = 38/213 (17%) Query: 282 TLESGHPRNLTCSVPWACEQGTP-PTITWM---------GASVSSLDPTITRSSMLSLIP 331 T+ GHP +L+C +G P P I+W GA + + + R L Sbjct: 2173 TVREGHPTSLSCEC-----RGVPFPKISWRKDGQPLPGEGAGLQHVS-AVGRLLYLGQAQ 2226 Query: 332 QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSV 391 Q+ + C + + ++ ++L + PPQ G T +SV Sbjct: 2227 LAQEGTYTCECSNVVGNS----SQDLQLEVHVPPQ------IAGPREPPT------QVSV 2270 Query: 392 LEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---QSSNLG-VLELPRVHVKDEGEFTCR 447 ++ L C PP ++W + Q N G L + R G ++C Sbjct: 2271 VQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCV 2330 Query: 448 AQNPLG--SQHISLSLSLQNEYTGKMRPISGVT 478 A+N G + LS+ + E G + P++ +T Sbjct: 2331 AENLAGRAERKFELSVLVPPELIGDLDPLTNIT 2363 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444 ++ + S+ L C V ++P ++W S LS + L L+L R + D G + Sbjct: 2947 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMY 3006 Query: 445 TCRAQNPLGSQHISLSLSL 463 TC A N G + LS+ Sbjct: 3007 TCEALNAAGRDQKLVQLSV 3025 Score = 34.3 bits (77), Expect = 0.33 Identities = 72/314 (22%), Positives = 102/314 (32%), Gaps = 96/314 (30%) Query: 158 SVTVQEGLCVSVPCSVLYPHYNWTASSPV-YGSWFKEGADIP----WDIPVATNTPSGKV 212 +V V EG VS+PC VL A P+ W K+G +P I + + Sbjct: 893 TVRVLEGQPVSLPCIVL-------AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRA 945 Query: 213 QEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALT 272 ++ GR+ + TN RD V+ R +H TA Sbjct: 946 LQEHAGRYSCVA---TNTAGSQHRDVE--------LVVQVPPR----------IHPTATH 984 Query: 273 HMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGAS--VSSLDPTITRSSMLSLI 330 H+ +P +L P PTITW + ++S P S Sbjct: 985 HITNEGVPASL------------PCVASGVPAPTITWTKETNALTSRGPHYNVSK----- 1027 Query: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390 GT L Q + AG + A + + Q + ++V N ALS Sbjct: 1028 -----EGTLLIAQPSAQDAGAYVCTATN-TVGFSSQEMRLSV------------NRLALS 1069 Query: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450 + W L PS G L L +V V D G + C A N Sbjct: 1070 ---------------------KYVWEEYGLLPS-----GSLRLAQVQVGDSGHYECTASN 1103 Query: 451 PLGSQHISLSLSLQ 464 P GS L +Q Sbjct: 1104 PAGSASHRYVLGVQ 1117 Score = 33.9 bits (76), Expect = 0.44 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%) Query: 378 TASTTLRNGSALSVL--EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS----QSSNLG-V 430 T + L G+A VL G + L C P ++ WT + P Q G V Sbjct: 1405 TPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV 1464 Query: 431 LELPRVHVKDEGEFTCRAQNPLGSQ 455 L + HV DEG + C A +P G Q Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQQ 1489 Score = 33.9 bits (76), Expect = 0.44 Identities = 43/185 (23%), Positives = 67/185 (36%), Gaps = 30/185 (16%) Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360 +G P +WMG +VS +D + R L D G S C + + +R+N Sbjct: 1921 KGHQPVSSWMGVTVS-VDGRVLRIEQAQL----SDAG-SYRCVASNVAGSTELRYGLRVN 1974 Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420 + PP+ TL VL + L C P L W + Sbjct: 1975 V--PPR--------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPV 2018 Query: 421 SPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLGS--QHISLSLSLQNEYTGKMR 472 SP+ + L VL L D G ++C A + +G Q + L + + G+ Sbjct: 2019 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEEL 2078 Query: 473 PISGV 477 +S V Sbjct: 2079 NVSVV 2083 Score = 33.9 bits (76), Expect = 0.44 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 369 TMTVFQGDGTASTTLRNGS-ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---- 423 T F+ + T+R+G A++V Q+ L C D P +SW + L P Sbjct: 3661 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720 Query: 424 QSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 + G L + V +D G + C A N GS Sbjct: 3721 EILPEGSLRIQPVLAQDAGHYLCLASNSAGS 3751 Score = 33.5 bits (75), Expect = 0.57 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 397 LHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPL 452 L L+C PP + W G +SP + + L +L++ + +D G ++C A N Sbjct: 2370 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 2429 Query: 453 GSQHISLSL------SLQNE 466 G + S+ S++NE Sbjct: 2430 GEARRNFSVEVLVPPSIENE 2449 Score = 33.1 bits (74), Expect = 0.74 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 386 GSALSVLE---GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVK 439 G A S L G S+ L C V +P + W L L S + G L + R Sbjct: 4222 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 4281 Query: 440 DEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRP 473 D G + C A+N +G + L LQ+ ++ P Sbjct: 4282 DAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 4315 Score = 32.7 bits (73), Expect = 0.97 Identities = 17/72 (23%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 393 EGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFTCRAQ 449 +G + + C+ P +SW+ S L ++ G L + V +D G ++C+A Sbjct: 621 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680 Query: 450 NPLGSQHISLSL 461 N +G+ +++L Sbjct: 681 NEVGTDQETVTL 692 Score = 29.6 bits (65), Expect = 8.2 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGE 443 A+ V G L C D+ P ++W L +Q + LE+ V D+G Sbjct: 3041 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 3100 Query: 444 FTCRAQNPLGSQHISLSLSLQ 464 ++C+ N G + +L++Q Sbjct: 3101 YSCKVSNVAGEAVRTFTLTVQ 3121 >gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3783 Score = 55.1 bits (131), Expect = 2e-07 Identities = 65/237 (27%), Positives = 86/237 (36%), Gaps = 43/237 (18%) Query: 233 LSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLE----SGHP 288 L I++A+ D G Y +V N + + + PTF P T +G P Sbjct: 1806 LEIQEAQVSDKGLYSCKVS------NVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP 1859 Query: 289 RNLTCSVPWACEQGTP-PTITW----MGASVSSLDPTITRSSMLSLIP-QPQDHGTSLTC 342 LTC V G P PT+TW M S++ ++R L L QP GT TC Sbjct: 1860 LVLTCDV-----SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTC 1913 Query: 343 QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402 A V + L + G A VLEGQ + L C Sbjct: 1914 VAENTQAEARKDFVVAV--------LVAPRIRSSGVAREH-------HVLEGQEVRLDCE 1958 Query: 403 VDSNPPARLSWTWGSLTLSPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLG 453 D PP ++W L +L G L L + D G +TC A NP G Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2015 Score = 49.3 bits (116), Expect = 1e-05 Identities = 104/458 (22%), Positives = 170/458 (37%), Gaps = 96/458 (20%) Query: 28 MQKSVTVQEGLCVSVLCSFS-YPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQ 86 +++ + V +G ++C+ + +PQ T WF+ G ++R Sbjct: 1169 LEEVIKVLDGQTAHLMCNVTGHPQPKLT--------WFKDGRPLARG------------- 1207 Query: 87 EETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQD 146 D H+ D L + S AG Y C+ + K+ QLSV + + Sbjct: 1208 ----DAHHISPD----GVLLQVLQANLSSAGHYS-CIAANAVGEKTKHFQLSVLLAPT-- 1256 Query: 147 LLSRYRLEVPESVTVQEGLCVSVPCSVL-YPHYNWTASSPVYGSWFKEGADIPWDIPVAT 205 +L E VTV +S+ C L +P N T W K+GA P++ Sbjct: 1257 ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNIT--------WMKDGA--PFEASRNI 1306 Query: 206 NTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDK 263 G THG L I +A+K D+G+Y V E G NY + Sbjct: 1307 QLLPG-----THG--------------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1347 Query: 264 LSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITW----MGASVSSLDP 319 L +++ + G E N T ++ PPTI W + SS Sbjct: 1348 LIP--PSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 1405 Query: 320 TITRSSMLSLIP-QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQ--GD 376 + +L + P Q D G L + G + + I PP +FQ GD Sbjct: 1406 VLGEGRLLQIQPTQVSDSGRYLCVATNVAGED---DQDFNVLIQVPP------MFQKVGD 1456 Query: 377 GTASTTL-------RNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN 427 +A+ + R G ++E +L C ++ PP L+W LS + Sbjct: 1457 FSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVS 1516 Query: 428 L----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSL 461 + VL++P V ++ G ++C+A N +G + L Sbjct: 1517 VLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 1554 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 18/111 (16%) Query: 359 LNISYPPQNLTMTVFQG-DGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS 417 +N+ PP T+ QG DG+ + R G ++ +VC V +PP +SW Sbjct: 2023 VNVLVPP-----TIKQGADGSGTLVSRPGELVT--------MVCPVRGSPPIHVSWLKDG 2069 Query: 418 LTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 L L SQ + L L + +V + D G FTC A +P G + +L +Q Sbjct: 2070 LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2120 Score = 44.7 bits (104), Expect = 2e-04 Identities = 62/243 (25%), Positives = 93/243 (38%), Gaps = 39/243 (16%) Query: 233 LSIRDARKGDSGKYYFQVER--GSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRN 290 L I A+ D+G Y GS + Y L V+V +P S+PG + P Sbjct: 659 LRIEQAQLSDAGSYRCVASNVAGSTELRY---GLRVNVPPRITLPP-SLPGPVLVNTPVR 714 Query: 291 LTCSVPWACEQGTPPTITWM--GASVSSLDP----TITRSSMLSLIPQPQDHGTSLTCQV 344 LTC+ A PT+ W+ G VS +L+L +C V Sbjct: 715 LTCNATGA----PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC-V 769 Query: 345 TLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVD 404 + G V L + PP + L +SV+ +S+ L C Sbjct: 770 AVSAVGEDRQDVV-LQVHMPP---------------SILGEELNVSVVANESVALECQSH 813 Query: 405 SNPPARLSWTWGSLTLSPSQ----SSNLGVLELPRVHVKDEGEFTCRAQNPLG--SQHIS 458 + PP LSW L P S++ +L++ R V D G +TC A N G +H + Sbjct: 814 AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYN 873 Query: 459 LSL 461 L++ Sbjct: 874 LNV 876 Score = 44.3 bits (103), Expect = 3e-04 Identities = 61/263 (23%), Positives = 102/263 (38%), Gaps = 41/263 (15%) Query: 222 LLGDPQTNNCSLSIRDARKGDSGKYYFQV--ERGSRKWNYIYDKLSVHVTALTHMPTFSI 279 LL SL + GDSG Y E G + ++ + V H+ Sbjct: 2165 LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF-----QLTVMEPPHIEDSGQ 2219 Query: 280 PG--TLESGHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLDPTITRSSMLSLIPQPQ 334 P +L G P L C QGTP P ITW G +++ L+ +S + + + + Sbjct: 2220 PTELSLTPGAPMELLCDA-----QGTPQPNITWHKDGQALTRLE----NNSRATRVLRVR 2270 Query: 335 DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEG 394 D G TC P + ++ R+ + PP + G G A G Sbjct: 2271 DAGL-YTCLAESPAGAIE--KSFRVRVQAPPNIV--------GPRGPRFVVGLA----PG 2315 Query: 395 QSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEFTCRAQN 450 Q L L C+V++ P +++W + L + L+L + D G+++C A+N Sbjct: 2316 Q-LVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 2374 Query: 451 PLGSQHISLSLSLQNEYTGKMRP 473 GS ++ + + T + P Sbjct: 2375 AAGSTSVAFRVEIHTVPTIRSGP 2397 Score = 42.4 bits (98), Expect = 0.001 Identities = 69/294 (23%), Positives = 111/294 (37%), Gaps = 62/294 (21%) Query: 189 SWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYF 248 +WFK+GA +P S KV GR L LG Q+++ + A Sbjct: 253 TWFKDGALLP---------TSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA---- 299 Query: 249 QVERGSRKWNYIYDKLSVHVTALTHMPTFSIPG------TLESGHPRNLTCSVPWACEQG 302 E+ +R L V+V PT G +G P L C +G Sbjct: 300 -AEKATR--------LDVYVP-----PTIEGAGGRPYVVKAVAGRPVALECVA-----RG 340 Query: 303 TP-PTITW----MGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAV 357 P PT++W + + S+ T S+L L + +C + P + +V Sbjct: 341 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV 400 Query: 358 RLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWG- 416 + + PPQ L V +G G +T + GQ L L C +P + W Sbjct: 401 EVQV--PPQLL---VAEGLGQVTTIV----------GQPLELPCQASGSPVPTIQWLQNG 445 Query: 417 --SLTLSPSQSSNLG-VLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEY 467 + L+ Q ++ G L + V + G F C+A N G+ + +S+ E+ Sbjct: 446 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEW 499 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 6/81 (7%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLG----VLELPRVHVKDEGEF 444 + VL+GQ+ HL+C V +P +L+W L+ + ++ +L++ + ++ G + Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232 Query: 445 TCRAQNPLG--SQHISLSLSL 463 +C A N +G ++H LS+ L Sbjct: 1233 SCIAANAVGEKTKHFQLSVLL 1253 Score = 42.4 bits (98), Expect = 0.001 Identities = 63/217 (29%), Positives = 89/217 (41%), Gaps = 37/217 (17%) Query: 279 IPGTLESGHPRNLTCSVPWA---CE-QGTP-PTITWM--GASVSSLDPTITRSSMLSLIP 331 +P +E+G P T A C+ +G+P P ITW G VS + T L+ Sbjct: 2754 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 2813 Query: 332 ---QPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA 388 + QD GT TC T A R V L I L + VF TTL + Sbjct: 2814 KNLEGQDAGT-YTC--TAENAVGRARRRVHLTI------LVLPVF-------TTLPGDRS 2857 Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHV--KDEGEFTC 446 L + G L L CA +P R+ WT ++ S G L R V +D G + C Sbjct: 2858 LRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC 2915 Query: 447 RAQNPLGSQ------HISLSLSLQNE-YTGKMRPISG 476 A+N +G H+ + LQ E ++ + P+ G Sbjct: 2916 WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 2952 Score = 38.9 bits (89), Expect = 0.014 Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 56/298 (18%) Query: 180 WTASSPV-YGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 238 WT+ P W K+ PV P +VQED L I + Sbjct: 149 WTSGVPTPQVEWTKDRQ------PVLPGGPHLQVQEDGQ--------------VLRITGS 188 Query: 239 RKGDSGKYYFQVERGSRKWNYIYD-KLSVHVTALTHMPTFSIPGTLESGHPRNLTCS-VP 296 GD G+Y Q S D +L VH PT I G+ E+G + V Sbjct: 189 HVGDEGRY--QCVAFSPAGQQARDFQLRVHAP-----PT--IWGSNETGEVAVMEDHLVQ 239 Query: 297 WACE-QGTP-PTITWM--GASV-SSLDPTITRSSMLSLIPQPQDHGTSL-TCQVTLPGAG 350 CE +G P P ITW GA + +S TR + + Q + TC+ + A Sbjct: 240 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS--NAV 297 Query: 351 VTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPAR 410 +A RL++ PP +G G ++ + G+ + L C +P Sbjct: 298 GAAEKATRLDVYVPP------TIEGAGGRPYVVK------AVAGRPVALECVARGHPSPT 345 Query: 411 LSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464 LSW L ++ S S L VL L G ++C A +P G + S+ +Q Sbjct: 346 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 403 Score = 38.9 bits (89), Expect = 0.014 Identities = 80/380 (21%), Positives = 131/380 (34%), Gaps = 69/380 (18%) Query: 120 VFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGL----CVSVPCSVLY 175 V +E+ + Y ++ NV S +L R+ VP +T+ L V+ P + Sbjct: 658 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 717 Query: 176 PHYNWTASSPVYGSWFKEGADI-PWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLS 234 N T + W K+G + P P P G+V L+ Sbjct: 718 ---NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV--------------------LT 754 Query: 235 IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCS 294 + AR DSG+Y + D+ V + HMP + L N + + Sbjct: 755 LASARASDSGRYSCVAVSAVGE-----DRQDVVLQV--HMPPSILGEELNVSVVANESVA 807 Query: 295 VPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGV--- 351 + PP ++W L P+P H ++ + + A V Sbjct: 808 LECQSHAMPPPVLSWW-------------KDGRPLEPRPGVHLSADKALLQVDRADVWDA 854 Query: 352 ---TMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPP 408 T + S NL + V LR L+V EG L C P Sbjct: 855 GHYTCEALNQAGHSEKHYNLNVWV-----APVFPLRESHTLTVREGHPTRLSCECRGVPF 909 Query: 409 ARLSWTWGSLTLSPSQSSNLG-------VLELPRVHVKDEGEFTCRAQNPLG--SQHISL 459 ++SW L P + + L +L L + + EG +TC N +G SQ + L Sbjct: 910 PKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQL 968 Query: 460 SLSLQNEYTGKMRPISGVTL 479 + + + G P + V++ Sbjct: 969 EVHVPPQIAGPREPPTQVSV 988 Score = 36.6 bits (83), Expect = 0.067 Identities = 43/188 (22%), Positives = 66/188 (35%), Gaps = 19/188 (10%) Query: 286 GHPRNLTCSVPWACEQGTP-PTITWM--GASVSSLD--PTITRSSMLSLIPQPQDHGTSL 340 G P L C G+P PTI W+ G L ++ + L + DH Sbjct: 422 GQPLELPCQA-----SGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLF 476 Query: 341 TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 400 CQ T V ++ + P L + + G + S+ +H Sbjct: 477 ACQATNEAGTAGAEVEVSVHGEWAPGVLEVPI----GQYHWGXEHHSSFPAACDPPVHRG 532 Query: 401 CAVDSNPPARLSWT-----WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQ 455 PP W WG T P S L++ +V ++DEG +TC A N G Sbjct: 533 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 592 Query: 456 HISLSLSL 463 ++L + Sbjct: 593 KREVALKV 600 Score = 36.2 bits (82), Expect = 0.088 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Query: 390 SVLEGQSLHLVCAVDSNPPARLSWTWG----SLTLSPSQSSNLGVLELPRVHVKDEGEFT 445 +VLE S+ L C PP +SW G S + + S + VL + + + D G + Sbjct: 614 AVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 673 Query: 446 CRAQNPLGSQHISLSL 461 C A N GS + L Sbjct: 674 CVASNVAGSTELRYGL 689 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 3/95 (3%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVKDEGEFT 445 ++V G + L C P + W L S+ G L L V D G + Sbjct: 3036 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 3095 Query: 446 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLG 480 C A N LGS L ++ E G ++GV G Sbjct: 3096 CVAHNLLGSATARAFLVVRGEPQGSWGSMTGVING 3130 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444 ++V ++ L C NP +SW L SPS + VL++ V D + Sbjct: 1573 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASY 1632 Query: 445 TCRAQNPLGSQHISLSLSLQ 464 C A+N GS +L +Q Sbjct: 1633 MCVAENQAGSAEKLFTLRVQ 1652 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEF 444 ++ + S+ L C V ++P ++W S LS + L L+L R + D G + Sbjct: 1665 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMY 1724 Query: 445 TCRAQNPLGSQHISLSLSL 463 TC A N G + LS+ Sbjct: 1725 TCEALNAAGRDQKLVQLSV 1743 Score = 33.9 bits (76), Expect = 0.44 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%) Query: 378 TASTTLRNGSALSVL--EGQSLHLVCAVDSNPPARLSWTWGSLTLSPS----QSSNLG-V 430 T + L G+A VL G + L C P ++ WT + P Q G V Sbjct: 123 TPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV 182 Query: 431 LELPRVHVKDEGEFTCRAQNPLGSQ 455 L + HV DEG + C A +P G Q Sbjct: 183 LRITGSHVGDEGRYQCVAFSPAGQQ 207 Score = 33.9 bits (76), Expect = 0.44 Identities = 43/185 (23%), Positives = 67/185 (36%), Gaps = 30/185 (16%) Query: 301 QGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLN 360 +G P +WMG +VS +D + R L D G S C + + +R+N Sbjct: 639 KGHQPVSSWMGVTVS-VDGRVLRIEQAQL----SDAG-SYRCVASNVAGSTELRYGLRVN 692 Query: 361 ISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTL 420 + PP+ TL VL + L C P L W + Sbjct: 693 V--PPR--------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPV 736 Query: 421 SPSQSSNL------GVLELPRVHVKDEGEFTCRAQNPLGS--QHISLSLSLQNEYTGKMR 472 SP+ + L VL L D G ++C A + +G Q + L + + G+ Sbjct: 737 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEEL 796 Query: 473 PISGV 477 +S V Sbjct: 797 NVSVV 801 Score = 33.9 bits (76), Expect = 0.44 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 369 TMTVFQGDGTASTTLRNGS-ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPS---- 423 T F+ + T+R+G A++V Q+ L C D P +SW + L P Sbjct: 2379 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2438 Query: 424 QSSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 + G L + V +D G + C A N GS Sbjct: 2439 EILPEGSLRIQPVLAQDAGHYLCLASNSAGS 2469 Score = 33.5 bits (75), Expect = 0.57 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 397 LHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGEFTCRAQNPL 452 L L+C PP + W G +SP + + L +L++ + +D G ++C A N Sbjct: 1088 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1147 Query: 453 GSQHISLSL------SLQNE 466 G + S+ S++NE Sbjct: 1148 GEARRNFSVEVLVPPSIENE 1167 Score = 33.1 bits (74), Expect = 0.74 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 386 GSALSVLE---GQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---GVLELPRVHVK 439 G A S L G S+ L C V +P + W L L S + G L + R Sbjct: 2940 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERD 2999 Query: 440 DEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRP 473 D G + C A+N +G + L LQ+ ++ P Sbjct: 3000 DAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 3033 Score = 30.4 bits (67), Expect = 4.8 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 29/90 (32%) Query: 389 LSVLEGQSLHLVCAVDSNPPARLSWT--------------------WGSL----TLSPSQ 424 +S + GQSL L C + P + W WG + L Q Sbjct: 28 VSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ 87 Query: 425 SSNLGVLELPRVHVKDEGEFTCRAQNPLGS 454 S L PR+ D G ++CRA+N G+ Sbjct: 88 S-----LHFPRIQEGDSGLYSCRAENQAGT 112 Score = 29.6 bits (65), Expect = 8.2 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 388 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL----GVLELPRVHVKDEGE 443 A+ V G L C D+ P ++W L +Q + LE+ V D+G Sbjct: 1759 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 1818 Query: 444 FTCRAQNPLGSQHISLSLSLQ 464 ++C+ N G + +L++Q Sbjct: 1819 YSCKVSNVAGEAVRTFTLTVQ 1839 >gi|40255013 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) [Homo sapiens] Length = 344 Score = 54.3 bits (129), Expect = 3e-07 Identities = 54/228 (23%), Positives = 93/228 (40%), Gaps = 35/228 (15%) Query: 230 NCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHM-PTFSIPG-TLESGH 287 N SL I++ + D+G Y QV + D ++ T H+ P P + + + Sbjct: 104 NASLLIQNVTQNDTGFYTLQVIKS--------DLVNEEATGQFHVYPELPKPSISSNNSN 155 Query: 288 PRNLTCSVPWACEQGTPPT--ITWMGASVSSLDPTITRSS---MLSLIPQPQDHGTSLTC 342 P +V + CE T + W+ + P + S+ L+L+ ++ S C Sbjct: 156 PVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYEC 215 Query: 343 QVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCA 402 ++ P A + V LN+ Y P T++ S + G++L+L C Sbjct: 216 EIQNP-ASANRSDPVTLNVLYGPDGPTISP--------------SKANYRPGENLNLSCH 260 Query: 403 VDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450 SNPPA+ SW +Q L +P + V + G + C+A N Sbjct: 261 AASNPPAQYSWFINGTFQQSTQE-----LFIPNITVNNSGSYMCQAHN 303 >gi|126517478 peroxidasin homolog-like [Homo sapiens] Length = 1463 Score = 54.3 bits (129), Expect = 3e-07 Identities = 85/317 (26%), Positives = 129/317 (40%), Gaps = 43/317 (13%) Query: 158 SVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTH 217 SVTV+E C S + + + VY + EG P +I N S +++DT Sbjct: 223 SVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKP-EIIWIHNNHSLDLEDDTR 281 Query: 218 GRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTF 277 L + D T L IR+ R+ D G Y + + + ++L P+F Sbjct: 282 ---LNVFDDGT----LMIRNTRESDQGVYQCMARNSAGEAKT--QSAMLRYSSLPAKPSF 332 Query: 278 SI-PGTLES--GHPRNLTCSVPWACEQGTP-PTITWMGASVSSLDPT--ITRSSMLSLIP 331 I P E G L C G P P ITW + LD + + SS L L Sbjct: 333 VIQPQDTEVLIGTSTTLECMAT-----GHPHPLITWTRDNGLELDGSRHVATSSGLYLQN 387 Query: 332 QPQ-DHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390 Q DHG TC + T+ A + + PPQ TV D Sbjct: 388 ITQRDHGR-FTCHAN--NSHGTVQAAANIIVQAPPQ---FTVTPKDQV------------ 429 Query: 391 VLEGQSLHLVCAVDSNPPARLSWT--WGSLTLSPSQSS-NLGVLELPRVHVKDEGEFTCR 447 VLE ++ +C D NPP + WT G L + + + G L + R D+G++ C+ Sbjct: 430 VLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQ 489 Query: 448 AQNPLGSQHISLSLSLQ 464 A + LG + +S+ L+++ Sbjct: 490 AVSSLGVKKVSVQLTVK 506 Score = 38.9 bits (89), Expect = 0.014 Identities = 93/444 (20%), Positives = 154/444 (34%), Gaps = 100/444 (22%) Query: 31 SVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQEETR 90 SVTV+E C S +F PQ+ S + RA + I NN + ++++TR Sbjct: 223 SVTVEEFNCQSPRITFE-PQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTR 281 Query: 91 DRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSR 150 D TL IR+TRESD G Y C+ R S +Q + R Sbjct: 282 LNVF-------DDGTLMIRNTRESDQGVYQ-CMARN-----------SAGEAKTQSAMLR 322 Query: 151 YR--------LEVPESVTVQEGLCVSVPCSVL---YPHYNWTASSPVYGSWFKEGADIPW 199 Y + P+ V G ++ C +P WT + G ++ Sbjct: 323 YSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDN---------GLELDG 373 Query: 200 DIPVATNTP--SGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKW 257 VAT++ + + HGRF NN +++ A Sbjct: 374 SRHVATSSGLYLQNITQRDHGRFTC----HANNSHGTVQAA------------------- 410 Query: 258 NYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQ--GTPPTITWM---GA 312 ++ V A + H +V W CE PP I W G Sbjct: 411 ------ANIIVQAPPQFTVTPKDQVVLEEH------AVEWLCEADGNPPPVIVWTKTGGQ 458 Query: 313 SVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTV 372 T+ S L + Q CQ + GV + V + ++ P+ L + Sbjct: 459 LPVEGQHTVLSSGTLRIDRAAQHDQGQYECQ-AVSSLGV---KKVSVQLTVKPKALAV-- 512 Query: 373 FQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNL---G 429 T L +++ V G+++++ C P ++W + ++ S ++ G Sbjct: 513 -------FTQLPQDTSVEV--GKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEG 563 Query: 430 VLELPRVHVKDEGEFTCRAQNPLG 453 L + D+G + C A+N G Sbjct: 564 TLTIYDAGFPDQGRYECVARNSFG 587 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,586,351 Number of Sequences: 37866 Number of extensions: 1268003 Number of successful extensions: 6496 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 119 Number of HSP's successfully gapped in prelim test: 218 Number of HSP's that attempted gapping in prelim test: 4734 Number of HSP's gapped (non-prelim): 1530 length of query: 595 length of database: 18,247,518 effective HSP length: 108 effective length of query: 487 effective length of database: 14,157,990 effective search space: 6894941130 effective search space used: 6894941130 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.