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Search of human proteins with 163914392
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163914392 glioma tumor suppressor candidate region gene 1
[Homo sapiens]
(1560 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 3152 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 197 5e-50
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 162 3e-39
gi|54792088 hypothetical protein LOC23506 [Homo sapiens] 157 6e-38
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 145 2e-34
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 140 1e-32
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 136 2e-31
gi|160707881 formin 2 [Homo sapiens] 130 8e-30
gi|116284392 mucin 2 precursor [Homo sapiens] 129 2e-29
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 127 8e-29
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 127 8e-29
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 127 8e-29
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 127 8e-29
gi|47132519 Ras association and pleckstrin homology domains 1 is... 126 2e-28
gi|112421108 capicua homolog [Homo sapiens] 126 2e-28
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 121 5e-27
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 117 1e-25
gi|150170670 piccolo isoform 2 [Homo sapiens] 116 1e-25
gi|150378539 piccolo isoform 1 [Homo sapiens] 116 1e-25
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 110 1e-23
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 110 1e-23
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 110 1e-23
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 105 3e-22
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 105 4e-22
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 102 2e-21
gi|55750053 atrophin-1 [Homo sapiens] 102 3e-21
gi|55750041 atrophin-1 [Homo sapiens] 102 3e-21
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 100 1e-20
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 100 1e-20
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 100 1e-20
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 3152 bits (8173), Expect = 0.0
Identities = 1560/1560 (100%), Positives = 1560/1560 (100%)
Query: 1 MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDNPGEAQSAFYEGPGLHVQEASGNH 60
MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDNPGEAQSAFYEGPGLHVQEASGNH
Sbjct: 1 MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDNPGEAQSAFYEGPGLHVQEASGNH 60
Query: 61 LNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEA 120
LNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEA
Sbjct: 61 LNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEA 120
Query: 121 EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQA 180
EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQA
Sbjct: 121 EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQA 180
Query: 181 LVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQ 240
LVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQ
Sbjct: 181 LVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQ 240
Query: 241 PVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATT 300
PVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATT
Sbjct: 241 PVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATT 300
Query: 301 LNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLP 360
LNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLP
Sbjct: 301 LNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLP 360
Query: 361 PKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQ 420
PKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQ
Sbjct: 361 PKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQ 420
Query: 421 ANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV 480
ANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV
Sbjct: 421 ANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV 480
Query: 481 QLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAH 540
QLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAH
Sbjct: 481 QLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAH 540
Query: 541 ILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD 600
ILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD
Sbjct: 541 ILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD 600
Query: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ 660
GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ
Sbjct: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ 660
Query: 661 ATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA 720
ATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA
Sbjct: 661 ATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA 720
Query: 721 SVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLP 780
SVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLP
Sbjct: 721 SVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLP 780
Query: 781 HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ 840
HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ
Sbjct: 781 HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ 840
Query: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900
LGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA
Sbjct: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900
Query: 901 PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALL 960
PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALL
Sbjct: 901 PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALL 960
Query: 961 ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020
ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA
Sbjct: 961 ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020
Query: 1021 PMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSK 1080
PMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSK
Sbjct: 1021 PMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSK 1080
Query: 1081 EACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETV 1140
EACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETV
Sbjct: 1081 EACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETV 1140
Query: 1141 STQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDE 1200
STQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDE
Sbjct: 1141 STQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDE 1200
Query: 1201 YVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVT 1260
YVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVT
Sbjct: 1201 YVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVT 1260
Query: 1261 WARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSK 1320
WARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSK
Sbjct: 1261 WARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSK 1320
Query: 1321 VVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP 1380
VVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP
Sbjct: 1321 VVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP 1380
Query: 1381 HCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELY 1440
HCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELY
Sbjct: 1381 HCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELY 1440
Query: 1441 QRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEH 1500
QRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEH
Sbjct: 1441 QRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEH 1500
Query: 1501 LQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTLTR 1560
LQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTLTR
Sbjct: 1501 LQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTLTR 1560
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 197 bits (502), Expect = 5e-50
Identities = 349/1427 (24%), Positives = 486/1427 (34%), Gaps = 226/1427 (15%)
Query: 73 DLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEAEAELDLGPFQ-- 130
DL + + G+P + G + D L Q+ + + + Q+ + E+ L P
Sbjct: 531 DLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATL 590
Query: 131 --------LPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALV 182
LP +PA P G +A+V P S GP L +L+
Sbjct: 591 AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSA------GP---LLKSSLI 641
Query: 183 PPQDVVNKALSVQPF-LQPV---GLGNVTLQPIPGLQGLPNGSPGG-----ATAATLGLA 233
P S P + P G T P L+G + +P T TL L
Sbjct: 642 TPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLV 701
Query: 234 PIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNL 293
P PV T LA V S PS P G G+ L
Sbjct: 702 PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD-GISHTSAL 760
Query: 294 SAAVATTLNGNSVFGGAGAASAPTGT-------PSGQPLAVAPGLGSSPLVPA---PNVI 343
+ ++ + GA A ++ GT PS ++V+P P P+
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
Query: 344 LHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQ----PKAPQNLTF 399
+ +P+ P A LP +PA P P P +P+ +T
Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880
Query: 400 MAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIV 459
+VV FP KQ PA + ++ P+ A P +
Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940
Query: 460 IPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQN 519
P P G PA P+ PA A P G
Sbjct: 941 TPPAATPPSPK-----GGPATPSPKWAPTPPA--------ATPPSPKG------------ 975
Query: 520 LAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAG-PA 578
GP + P AP A + P G PA P A + P + P+P G PA
Sbjct: 976 --GPATPSPKGAPTPPA------ATPPSPKGGPAT---PSPKGAPTPPAVTPPSPKGSPA 1024
Query: 579 ATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLG 638
AT +G + PP+A P A T AA + + + P P P P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
Query: 639 LQQPQAQQPPQAPTPQAA-APPQATTPQPSPGLASSPEKIVLGQP--PSATPTAILTQDS 695
P + P P+P+ A PP AT P P GLA+ P K G P P+ATP +
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK---GAPTTPAATPPS------ 1135
Query: 696 LQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA-PDSQ- 753
P+ P P + PA A PP+ ATP KGA P A P S
Sbjct: 1136 -----PKGGLATPPPKGAP--TTPA-----ATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Query: 754 ---ASPAP--APQIPAAAP------LKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
A+P+P AP PAA P L P P +P+ P P L +P P P+
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 803 PPSRPQSVSRPPSEPPLH--PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP 860
P + P S P+ PP P PP PP+L G L PP P P PP P
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSP 1297
Query: 861 PLRPQSQPPEG-PLPPA---------PHLPP---SSTSSAVA-SSSETSSRLPAPTPSDF 906
P + PP+G P PPA P PP + T AV S + + LPA TPS
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS-- 1355
Query: 907 QLQFPPSQGPHKSPTPP-PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
P + + PTPP T PA PP P R PA+P PK
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG--------PAIPSPKG------D 1401
Query: 966 VPSGIILQNKAGGAPAAPQT-----STSLGPLTSPAASVLVSGQAPSG------------ 1008
S ++ APA P T + S G LT PA + + +AP+
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461
Query: 1009 ---------TPTAPSHAPAPAPMAATGLPPLLPAENKAF-ASNLPTLNVAKAASSGPGKP 1058
TP +P PAP +A + P PA A LP + + + P P
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV-IPSSPKEVPATP 1520
Query: 1059 SG----LQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRL 1114
S + + L K P TL P KEA + +V P A P+ ++A
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAP-KEALIPPAM-----TVPSPKKTPAIPTPKEAPATP 1574
Query: 1115 LPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVM 1174
+PS Y E + + + S P+
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP- 1633
Query: 1175 IDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPG-HGPLSSS--- 1230
+ T+ + K+ P S + +G + +S+G LP GP +
Sbjct: 1634 ------KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG--LPAKKGPTALKEVL 1685
Query: 1231 -APGASTQPPPHLPTKL--VIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDG 1287
AP + P PT+ + A P A + S+ + A L +D
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745
Query: 1288 PMPSRNRP-------PIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATL 1340
++ + P+ E+++ L A KV+ V P PP +L
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPL-----TAAAFEKVLPKPESASVSAAPSPPVSL 1800
Query: 1341 KVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPL 1387
+A P P P PP Q + +P KPL A LPL
Sbjct: 1801 PLA---PSPVPTLPPKQQFLPSSPGLVLESPS-KPLAPADEDELLPL 1843
Score = 174 bits (441), Expect = 6e-43
Identities = 372/1502 (24%), Positives = 510/1502 (33%), Gaps = 247/1502 (16%)
Query: 173 PTVLTHQALVP--PQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNG--SPGGATAA 228
P V+T+ + P A V P + + N+ L P P A
Sbjct: 440 PLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVAT 499
Query: 229 TLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLV 288
TL + + P N P+S L+ + P L + P +L A SP AGL
Sbjct: 500 TLRIPVSPPLPDPEDLKNLPSSVLV--KFPTQKDLQTV-----PASLEGAPFSPAQAGLT 552
Query: 289 IQKN---LSAAVATTLNGNSVFGGAGAASAPTGTPS-------GQPLAVAPGLGS--SPL 336
+K+ L A N S + + P + G+PL + S SPL
Sbjct: 553 TKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPL 612
Query: 337 VPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQN 396
+ + +T + P AG L K +TP A L G P K
Sbjct: 613 GVNSSASVIKTDSYAGPDSAGPLL-KSSLITP---TVAAFPLESADPAGVAPTTAKGTST 668
Query: 397 LTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSK--PMSVHLLNQ 454
T A+ V L+ P + + P T P P + P++ +L
Sbjct: 669 YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728
Query: 455 GSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPI 514
+P+ + P PG V SAL A V +G A+
Sbjct: 729 EIPKSVPSPSLPPAGTP---PGTKKVDGISHTSAL-APVASSPKECPTEDSGASATASSK 784
Query: 515 LTNQNLA-GPLSLGPVLAPHSGAHSAHILSAAP-IQVGQPALFQMPVS---LAAGSLPTQ 569
T LA P LG ++P + SA P +G + PV L SL Q
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
Query: 570 SQ------------PAPAG---PAATTVL--QGVTLPPSAV---AMLNTPDGLVQPATPA 609
P+P G P+A T L +GVTLPP +++N P PATPA
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 610 -------AATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ------APTPQAA 656
+ T + PAP+ PA +P P G P A PP P+P+ A
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPA--SPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQM--FLPQERSQQPLSAEGP 714
P A TP G ++P PP+ATP + + P + P S +G
Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
Query: 715 HLSVPASVIVSAPPPAQDPAP-----ATPVAKGAGLGPQA--PDSQASPAP-----APQI 762
+ P S PP A P+P ATP+ KGA P A P + PA AP
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 763 PAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPH-----------PTRPPSRPPSRPQSVS 811
PAA P G ++PS P AP+ + PSP PT P + PPS ++
Sbjct: 1083 PAATPPSPKGGPATPS-PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141
Query: 812 RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEG 871
PP P P P PP+ G L PPP P A PP P + P+G
Sbjct: 1142 TPP--PKGAPTTPAATPPSPKG------GLATPPPKGAPTTPAATPPSPKGGLATPSPKG 1193
Query: 872 -PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP--PTLHL 928
P PA PPS S + + PA TP P +G +P+P PT
Sbjct: 1194 APTTPAA-TPPSPKGGLATPSPKGAPTTPAATP-------PSPKGGLATPSPKGAPTT-- 1243
Query: 929 VPEPAAPPPPP---PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQT 985
PAA PP P P T P P P +L P N A P +P+
Sbjct: 1244 ---PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL-ATPPHKGAPNPAVVTPPSPKG 1299
Query: 986 STSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPP-----LLPAENKAFAS 1040
GP TSP P G PT P+ P P+P + G PP PA
Sbjct: 1300 ----GPATSP----------PKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Query: 1041 NLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDY 1100
PTL +S G PT SKE P
Sbjct: 1345 GTPTLPATTPSSKGG------------------PTTPSSKEG---------------PTP 1371
Query: 1101 KTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLL 1160
A PS + P A+PSP K D V K+ A
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSP----KGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 1161 EESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGH- 1219
++P A T ++L K A P G P SS+G
Sbjct: 1428 PSKGDLTPPAV-------------TPVSLKKAPATSAPK---------GGPATPSSKGDP 1465
Query: 1220 RLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSS--- 1276
LP P S P A Q K G+P++ SS ++ SS
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 1277 ----AASSLDADEDGPMPSRNR--PPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPV 1330
A+ L + + PP T + + + +EA + ++ +
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA-IPTPKEAPATP----SSKEAS 1580
Query: 1331 HQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPP---PAAPERKPLGTAP------- 1380
P P+T K A P PP T PP P +PE+ P AP
Sbjct: 1581 SPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640
Query: 1381 --------HCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIREL 1432
P P T + P A +G PA + L A E+T +I
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP-IITAP 1699
Query: 1433 AAVEDELYQRMLKGPPPEPAASAAQGTGDP-DWEAPG-LPPAKRRKSESPDVDQASFSSD 1490
+ + PP P SA G+ P AP L P ++ S++ AS S
Sbjct: 1700 TRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK 1759
Query: 1491 S----PQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPP 1546
P+ T +A + +L ++ + APS P + P+ P L + + P
Sbjct: 1760 GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS-PPVSLPLAPSPVPTLPPKQQFLP 1818
Query: 1547 SS 1548
SS
Sbjct: 1819 SS 1820
Score = 162 bits (410), Expect = 2e-39
Identities = 274/1113 (24%), Positives = 366/1113 (32%), Gaps = 191/1113 (17%)
Query: 139 GGAGP-TGAGGAAAVAAGPQALF--PGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQ 195
G AGP T G ++ + +A F S G + P TH P +V
Sbjct: 813 GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT-THSPTPPSPKGAPTPSAVT 871
Query: 196 PFLQPVGLGNVTLQP----IPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQ 251
P L P G VTL P P + LP G AT A P Q P +++ T +S
Sbjct: 872 P-LSPKG---VTLPPKETPTPSVVNLPFPKEGPATPA-----PKQA---PALSM-TSSSP 918
Query: 252 LLAKQVPV-SGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGA 310
A+ P G AS + P A+ SP+G G A S GG
Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKG-GPATPSPKWAPTPPAATPPSPKGGP 977
Query: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP 370
A +P G P+ P A P P P+P PTP P P TP P
Sbjct: 978 -ATPSPKGAPT-PPAATPPSPKGGPATPSPK----GAPTPPAVTPPS--PKGSPAATPFP 1029
Query: 371 FA----PAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVV--LSGFPAPALQANVF 424
PA + +G P A P AP G L G P P
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT--- 1086
Query: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHM------LPGQNQFLLPGAP 478
PP+ G A P P GA P + +G P + P + L P
Sbjct: 1087 --PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 479 AVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS 538
P +A P + G + A P LA P G P + S
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 539 AHILSAAPIQVGQPAL-----------FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT 587
A P G P P A + P + P+P G AT +G
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 588 LPPSAVAM-----LNTPD--GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQ 640
PP+A L TP G PA + + P + PPA + P P G
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG-- 1322
Query: 641 QPQAQQPPQAPTPQAAAPPQ--------ATTPQPSPGLASSPEKIVLGQPPSATPT---- 688
P P APTP A PP ATTP S G ++P PP+ATP+
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS-SKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 689 ------------------AILTQDSLQMFLPQERSQQPLSAEG----------PHLSVPA 720
T ++ P++ P++ EG P P
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441
Query: 721 SVIVSAPPPAQDPAPATPVAKGAGLGPQA--PDSQASPAPAPQIPAAAPLKGPG---PSS 775
S+ + A PATP +KG P P + PAP +++P K P P
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501
Query: 776 SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRP---------------------- 813
+P+LP P +P R P P + S P
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 814 -----PSEPPLHPC------PPPQAPPTLPGI-----FVIQNQLGVPPPASNPAPTAPGP 857
P E P P PP P T G +I + P P P P A P
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 858 PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH 917
P P P + P+G P +P + PSS + S + + ++ A P + P +GP
Sbjct: 1622 PSPEKGPATPAPKG-TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK-GLPAKKGPT 1679
Query: 918 --KSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNK 975
K P P AP P+T + T P P P A +G +K
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA--------KNG----SK 1727
Query: 976 AGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAEN 1035
+ AP + +S A + +P G P AP + A P+ A +LP
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKG-PLAPPESKASTPLTAAAFEKVLPKPE 1786
Query: 1036 KAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSV 1095
A S P+ V+ + P PTL P + + L G V
Sbjct: 1787 SASVSAAPSPPVSLPLAPSP-----------------VPTLPPKQ-----QFLPSSPGLV 1824
Query: 1096 LHPDYKTAFPSFEDALHRLLPYHVYQGALPSPS 1128
L K P+ ED L L+P G +P S
Sbjct: 1825 LESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857
Score = 139 bits (349), Expect = 3e-32
Identities = 259/1084 (23%), Positives = 375/1084 (34%), Gaps = 197/1084 (18%)
Query: 128 PFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDV 187
P PTL+ + P A + + FP + L PP+V A+ V
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNL----LTSPPSV----AVAESGSV 172
Query: 188 VNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMAL-- 245
+ + + P L V + +P +G P+ +T + P+ + V +L
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232
Query: 246 NTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAG-LVIQKNLSAAVATTLNGN 304
TPT+ L A A+ + T++S +SPQ G L ++ +S A +L+
Sbjct: 233 TTPTTTL-----------AIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQ 281
Query: 305 SV-FGGAGAASAPTGTPSGQPLAVAPGL--------GSSPLV--PAPNVILHRTPTPIQP 353
S+ + +A TP P+++ L GS L+ P+ + T I
Sbjct: 282 SLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISV 341
Query: 354 KPAGV---LPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVV 410
+ P + + P P T+ P P K P ++ + +G V
Sbjct: 342 DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV 401
Query: 411 LSGFPAPALQANVFKQPPATT--------------------------------------T 432
+ F + + K P T T
Sbjct: 402 ATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVAT 461
Query: 433 GAAPPQPPGALS--KPMSVHLL------------NQGSSIVIPAQHMLPGQNQFL-LPGA 477
+PP G +S +P S L +++ IP LP LP +
Sbjct: 462 CVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSS 521
Query: 478 PAVQLPQQ--LSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP--------LSLG 527
V+ P Q L +PA++ G + A G +P + A P S
Sbjct: 522 VLVKFPTQKDLQTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSS 579
Query: 528 PVLAPHSGAHSAHILSAAPIQVGQPA---LFQMPVSLAAGSLPTQSQPAP--AGPAATTV 582
P + A A P+ +G+PA + V+ +A + T S P AGP +
Sbjct: 580 PEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSS 639
Query: 583 LQGVTLPPSAVAMLNTPDGLVQPAT---PAAATGEAAPVL--TVQPAPQAPPA-VSTPLP 636
L +T +A + + V P T + T A+P L TV AP+ P T
Sbjct: 640 L--ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTT 697
Query: 637 LGLQQPQAQQPPQAPTPQAAAPPQAT---TPQ-----PSPGLASSPEKIVLGQPPSATPT 688
L L ++ P AP+PQ P AT P+ PSP L PP+ TP
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL-----------PPAGTPP 746
Query: 689 AILTQDSL---QMFLPQERSQQPLSAEGPHLSVPAS------VIVSAPPP---AQDPAPA 736
D + P S + E S AS + +P P + P
Sbjct: 747 GTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK 806
Query: 737 TPVAKGAGLGPQAP----DSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
P K GP P S SP A +P + L G SP+ H SP P
Sbjct: 807 RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS-LSFQGSKDSPATTH------SPTPP 859
Query: 793 SPHPTRPPSR-PPSRPQSVSRPPSEPPLHPC---------PPPQAPPTLPGIFVIQNQ-- 840
SP PS P P+ V+ PP E P P AP P + + +
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919
Query: 841 --LGVPPPASNPA-PTAPGPPQPPLRPQSQPPEGPLPPAPH---LPPSSTSSAVASSSET 894
P P PA P+ G P PP P GP P+P PP++T + T
Sbjct: 920 KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979
Query: 895 SSRLPAPTPSDFQLQFPPS-QGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP-- 951
S APTP PPS +G +P+P P P A PP P+ TPFP
Sbjct: 980 PSPKGAPTP---PAATPPSPKGGPATPSPKG----APTPPAVTPPSPKG-SPAATPFPKG 1031
Query: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
A P A P+ L A PAA S GP T S+ + P+ TP
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT---PSLKGAPTPPAATPP 1088
Query: 1012 APSHAPA-PAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGL 1070
+P PA P+P A P P K + P ++ P P G GL
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG--------GL 1140
Query: 1071 KKPP 1074
PP
Sbjct: 1141 ATPP 1144
Score = 110 bits (275), Expect = 1e-23
Identities = 315/1423 (22%), Positives = 478/1423 (33%), Gaps = 240/1423 (16%)
Query: 209 QPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAG 268
QP LP S TAA +GQP L P S +Q P+S ++
Sbjct: 18 QPQAETAVLPMSSALSVTAA---------LGQPGPTLPPPCSPA-PQQCPLSAANQASPF 67
Query: 269 PSEPVTLASAGVS---PQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPL 325
PS P T+AS + PQ + +A A T N + G +P P+
Sbjct: 68 PS-PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLI----GPPISPAALALASPM 122
Query: 326 AVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPK-PFAPAGATLTIQGEP 384
+AP L +P AP ++ P +Q A PP L P A +G+ +T+
Sbjct: 123 -IAPTLKGTPSSSAPLALVALAPHSVQKSSA--FPPNLLTSPPSVAVAESGSVITLSAP- 178
Query: 385 GALPQQPKA-----PQNLTFMAAGKAGQNVVLSGFP------APALQANVFKQP---PAT 430
P +PK P + G ++S P ++Q+ V P P T
Sbjct: 179 -IAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
Query: 431 TTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALP 490
T A PQ K ++ SS++I Q+ PG P +P L +LP
Sbjct: 238 TLAIASPQV-----KDTTI------SSVLISPQN--PGSLSLKGPVSPPAALSLSTQSLP 284
Query: 491 ANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAP--HSGAHSAHILS-AAPI 547
Q A P+T P+SLG LAP S S +L P
Sbjct: 285 VVTSSQ--KTAGPNTPPDF-------------PISLGSHLAPLHQSSFGSVQLLGQTGPS 329
Query: 548 QVGQPALFQMPV--SLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQP 605
+ P + + V S S P+Q P P+ V+ VA P P
Sbjct: 330 ALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVA----PSVDKGP 385
Query: 606 ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQ 665
+T ++ T + L V + P S L +P A
Sbjct: 386 STISSITCSPSGSLNVATSFSLSPTTSLILK--------------SSPNATYHYPLVAQM 431
Query: 666 PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVS 725
P + ++P + +A PT T + + S P+S P + PA++++
Sbjct: 432 PVSSVGTTPLVVTNPCTIAAAPT---TTFEVATCVSPPMSSGPISNIEP--TSPAALVM- 485
Query: 726 APPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPL 785
AP ++P+ + P PD P +P++ +K P ++P A L
Sbjct: 486 APVAPKEPSTQVATTLRIPVSPPLPD----PEDLKNLPSSVLVKFPTQKDLQTVP--ASL 539
Query: 786 GDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP 845
+P P+ P P + P + P P P + + LG P
Sbjct: 540 EGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPL 599
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PA + P L +S++S + + S
Sbjct: 600 PIGKPASSMTSP---------------------LGVNSSASVIKTDSYAG---------- 628
Query: 906 FQLQFPPSQGPH-KSPTPPPTLHLVP----EPAAPPPPPPR-TFQMVTTPFPALPQPKAL 959
P S GP KS PT+ P +PA P + T TT P L +L
Sbjct: 629 -----PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL 683
Query: 960 LERFHQVPSGII-----LQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPS------G 1008
+ H V G + + + P AP + PL + + + PS G
Sbjct: 684 APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
Query: 1009 TPTAP------SHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQ 1062
TP SH A AP+A++ P P E+ ++ + + P P G+
Sbjct: 744 TPPGTKKVDGISHTSALAPVASS--PKECPTEDSGASATASSKGTLTYLADSPS-PLGVS 800
Query: 1063 YESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQG 1122
+ K+PPT K + + + S + P + P E++L +QG
Sbjct: 801 VSPQT---KRPPT---KKGSAGPDTPIGNLSSPVSPVEASFLP--ENSLS-------FQG 845
Query: 1123 ALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQE 1182
+ SP+ H T + T + + + + +P+ +V + F +E
Sbjct: 846 SKDSPATTHS-----PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP--FPKE 898
Query: 1183 EKTTLALDK----QLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQP 1238
T A + + P + ++ G+P + S +G P S G +T
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958
Query: 1239 PPHLPTKLVIRHGGAGGSPSVTWAR-ASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
P PT G P+ + A + +++ S + + + P P PP
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018
Query: 1298 KTYEARSRIGLKLKIKQEAG-------------LSKVVHNTALDPVHQPPPPPAT--LKV 1342
+ K A L K T + P PAT LK
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 1343 AEPPPRPPPPPPPTGQMNGTVDHP--PPAAPERKP---LGTAPHCPRLPLRKTYRENVGG 1397
A PP PP P G + PPAA P L T PH G
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH-------------KGA 1125
Query: 1398 PGAPEGTPAGRARG-GSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAA 1456
P P TP G +P P A A + + + L KG P PAA+
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATP-----PSPKGGLATPPPKGAPTTPAATPP 1180
Query: 1457 QGTGDPDWEAP-GLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
G +P G P SP + ++ SP+ T + S P
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSP---KGGLATPSPKGAPTTP--AATPPSPKGGLATP 1235
Query: 1516 GRTPAPSYPHA---ASAGTPASPPP--LHRPEAYPPSSHNGGL 1553
AP+ P A + G PA+PPP P A P S GGL
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278
Score = 107 bits (267), Expect = 9e-23
Identities = 281/1179 (23%), Positives = 402/1179 (34%), Gaps = 245/1179 (20%)
Query: 466 LPGQNQFLLPGAPAVQLPQ---QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAG 522
+PG+ +P A +LPQ + + LP + + AA GQ L
Sbjct: 1 MPGEATETVP-ATEQELPQPQAETAVLPMSSALSVTAAL-----GQ-------PGPTLPP 47
Query: 523 PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTV 582
P S P P S A+ A + P P S + +LP + P A T
Sbjct: 48 PCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGT-----APEAPTF 102
Query: 583 LQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQP 642
L + PP + PA A A+ AP L P+ AP A+ P +Q+
Sbjct: 103 LPNLIGPP------------ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQK- 149
Query: 643 QAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP--PSATPTAILTQDSLQMFL 700
+A PP T PS +A S I L P PS T + S +
Sbjct: 150 -----------SSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPN 198
Query: 701 PQERSQQP--LSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQ-ASPA 757
P+ P +S H P + I S P T +A + PQ D+ +S
Sbjct: 199 PKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIAS---PQVKDTTISSVL 255
Query: 758 PAPQIPAAAPLKGP-GPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSE 816
+PQ P + LKGP P ++ SL Q+ P + S T P+ PP P +S
Sbjct: 256 ISPQNPGSLSLKGPVSPPAALSLSTQS----LPVVTSSQKTAGPNTPPDFP--ISLGSHL 309
Query: 817 PPLHPC------------PPPQAPPTLPGIFVIQNQLG---------VPP-PASN---PA 851
PLH P + PT+ I V + G +PP P+ N PA
Sbjct: 310 APLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPA 369
Query: 852 PTAPGPPQPP--------LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS-------S 896
A P P + + P G L A S T+S + SS + +
Sbjct: 370 TVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVA 429
Query: 897 RLP-------------------APTPSDFQLQF----PPSQGPHKSPTPPPTLHLVPEPA 933
++P APT + F++ P S GP + P LV P
Sbjct: 430 QMPVSSVGTTPLVVTNPCTIAAAPT-TTFEVATCVSPPMSSGPISNIEPTSPAALVMAPV 488
Query: 934 APPPPPPRTFQMVTTPF-PALPQPKALLERFHQVPSGIIL----QNKAGGAPAAPQTSTS 988
AP P + + P P LP P E +PS +++ Q PA+ +
Sbjct: 489 APKEPSTQVATTLRIPVSPPLPDP----EDLKNLPSSVLVKFPTQKDLQTVPASLE---- 540
Query: 989 LGPLTSPAASVLVSGQAPSGTP---TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL 1045
G SPA + L + + P+ P AP ++P+ +++ PL P A S L
Sbjct: 541 -GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPL 599
Query: 1046 NVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFP 1105
+ K ASS S L S S +K P L + S++ P AFP
Sbjct: 600 PIGKPASS---MTSPLGVNSSASVIKTDSYAGPDSAGPLL------KSSLITPTV-AAFP 649
Query: 1106 SFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRT----QAMLNKYRLL-LL 1160
L P V S Y F + L + + L L+
Sbjct: 650 -----LESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 1161 EESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEG-H 1219
E+ V+PS + TL L ++ K P S LP A + G
Sbjct: 705 SENCPVAPSPQNTC-------APLATLVLAPEIPKSVP--------SPSLPPAGTPPGTK 749
Query: 1220 RLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAAS 1279
++ G S+ AP AS+ P PT+ S +S+++SS
Sbjct: 750 KVDGISHTSALAPVASS--PKECPTE--------------------DSGASATASSKGTL 787
Query: 1280 SLDADEDGPM-----PSRNRPPIKTYEA--RSRIG--------LKLKIKQEAGLSKVVHN 1324
+ AD P+ P RPP K A + IG ++ E LS
Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
Query: 1325 TALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAA-----PERKPLGTA 1379
+ H P PP P P P P G + P P+ P+ P A
Sbjct: 848 DSPATTHSPTPPSPK---GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 1380 P-HCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDE 1438
P P L + + + AP+G PA + G+P P A G
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP----- 959
Query: 1439 LYQRMLKGPPPEPAASAAQGTGDPDWEAP-GLPPAKRRKSESPDVDQASFS-SDSPQDDT 1496
K P PAA+ G P +P G P SP A+ S +P
Sbjct: 960 ------KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 1497 LTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
+T + + +P TP P A TP SP
Sbjct: 1014 VTPP---------SPKGSPAATPFPKGASTPPAATPPSP 1043
Score = 83.6 bits (205), Expect = 1e-15
Identities = 281/1278 (21%), Positives = 416/1278 (32%), Gaps = 170/1278 (13%)
Query: 349 TPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP--KAPQNLTFMAAGKAG 406
T P LP + P + A + G+PG P APQ AA +A
Sbjct: 6 TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA- 64
Query: 407 QNVVLSGFPAPALQANVFKQPP--------ATTTGAAPPQP---PGALSKPMSVHLLNQG 455
S FP+P+ A+ + P A G AP P P + P+S L
Sbjct: 65 -----SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALA 119
Query: 456 SSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQL-IANPI 514
S ++ P P + L A A Q+ SA P N+ + A +G + ++ PI
Sbjct: 120 SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI 179
Query: 515 LTNQNLAGPLSLGPVLAPH-SGAHSAH-ILSAAPIQVGQP-ALFQMPVSLAAGSLPTQSQ 571
++ + + P+ G S I+S P P A Q V+ + PT +
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239
Query: 572 PAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQP---APQAP 628
+ T + V + P L+ G V P + + ++ PV+T P P
Sbjct: 240 AIASPQVKDTTISSVLISPQNPGSLSLK-GPVSPPAALSLSTQSLPVVTSSQKTAGPNTP 298
Query: 629 PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPT 688
P P+ LG AP Q++ Q P S P + S+T
Sbjct: 299 P--DFPISLGSHL--------APLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348
Query: 689 AILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQ 748
+ +Q S+ LP P + A+ V AP + P+ + +
Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATV--------AAFPVVAPSVDKGPSTISSITC------- 393
Query: 749 APDSQASPAPAPQI-PAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRP 807
+P + A + + P + + P+++ P A + S +P P + P
Sbjct: 394 SPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAP 453
Query: 808 QSVSRPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865
+ + PP+ P PT P V+ AP AP P +
Sbjct: 454 TTTFEVATCVSPPMSSGPISNIEPTSPAALVM-------------APVAPKEPSTQVATT 500
Query: 866 SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPT 925
+ P P P P + S+V T L S F P+Q + P
Sbjct: 501 LRIPVSPPLPDPE-DLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTV 559
Query: 926 LHLVPEPAAPPPPPPRTFQMVTTPFPALP-QPKA-LLERFHQVPSGIILQNKAGGAPAAP 983
L LV AAP P +FQ T+ P +P P+A L ++ P I G PA+
Sbjct: 560 LPLVQ--AAPKNSP--SFQS-TSSSPEIPLSPEATLAKKSLGEPLPI-------GKPASS 607
Query: 984 QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLP 1043
TS PL +++ ++ + +G +A P T P E+ A P
Sbjct: 608 MTS----PLGVNSSASVIKTDSYAGPDSA---GPLLKSSLITPTVAAFPLESADPAGVAP 660
Query: 1044 TLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTA 1103
T AK S+ S + K P + + L V T
Sbjct: 661 T--TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTC 718
Query: 1104 FPSFEDALHRLLPYHVYQGALP---SPSDYHKVDEEFETVS------------TQLLKRT 1148
P L +P V +LP +P KVD T + T+ +
Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778
Query: 1149 QAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQL-----------AKEK 1197
+K L L +S SP V +K + D + A
Sbjct: 779 ATASSKGTLTYLADSP--SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL 836
Query: 1198 PDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSS----APGASTQPPPHLPTKLVIRHGGA 1253
P+ +S S P S P P S+ +P T PP PT V+
Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896
Query: 1254 GGSPSVTWARASSSLSSSSSSSSAASSLDADED---GPMPSRNRPPIKTYEARSRIGLKL 1310
P+ + + +LS +SSS A + A + P P P + G
Sbjct: 897 KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 1311 KIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAA 1370
+ A P PP P P P PP G P P
Sbjct: 957 PSPKWA---------PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 1371 PERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIR 1430
P T P P + + P P TP + GSPA P T+
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTP--PAATPP--SPKGSPAATPLPKGAPTTP-AA 1062
Query: 1431 ELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAP---GLPPAKRRKSESPDVDQASF 1487
L + + LKG P PAA+ G P +P +PPA
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA-------------- 1108
Query: 1488 SSDSPQDDTLTEHLQSAIDSILNLQQAPG---RTPAPSYPHAASAGTP-------ASPPP 1537
+ SP+ T + A + +P TP P A TP A+PPP
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168
Query: 1538 LHRP--EAYPPSSHNGGL 1553
P A P S GGL
Sbjct: 1169 KGAPTTPAATPPSPKGGL 1186
Score = 51.6 bits (122), Expect = 6e-06
Identities = 88/351 (25%), Positives = 118/351 (33%), Gaps = 55/351 (15%)
Query: 1222 PGHGPLSSSAP-GASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASS 1280
P P ++ P GA T P LP+ G +PS+ A + + S A+
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPK-----GGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 1281 LDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTA-LDPVHQPPPPPAT 1339
+ + PMP PP + GL+ H A P PP P
Sbjct: 1098 --SPKGAPMPPAATPP----------------SPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 1340 LKVAEPPPRPPPPPP---PTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVG 1396
L A PPP+ P P P G PP AP P T P P+ L + G
Sbjct: 1140 L--ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT-PAATPPS-PKGGLATPSPK--G 1193
Query: 1397 GPGAPEGTPAGRARG-GSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASA 1455
P P TP G +P+P A A + + + L KG P PAA+
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATP-----PSPKGGLATPSPKGAPTTPAATP 1248
Query: 1456 AQGTGDPDWEAP--------GLPPAKRRKSESPD----VDQASFSSDSPQDDTLTEHLQS 1503
G P P PP+ + +P + A + SP+ T +
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 1504 AIDSILNLQQAPGRTPAPSYPHAAS---AGTPASPPPLHRPEAYPPSSHNG 1551
A +P +P P A A TP SP A PSS G
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 162 bits (409), Expect = 3e-39
Identities = 224/795 (28%), Positives = 279/795 (35%), Gaps = 121/795 (15%)
Query: 309 GAGAASAPTGTPSGQPLAVAPG-LGSSPLV-PAPNVILHRTPTP----IQPKPAGVLPPK 362
G A P TP + A A G L SSPL P+P+ R P P PA LPP
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA-TLPPS 334
Query: 363 LYQLTPKPFAPAGATL-----TIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAP 417
TP P AP + T+ P P Q M A P
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA-------------PP 381
Query: 418 ALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477
+LQ Q P + T + PP P+++ L +S+ P L + FL
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPS----PLALSSLQATTSLGSPT---LQATHSFLTMSP 434
Query: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAH 537
Q + PA+ AP + L A+P L SL P ++P S
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLS---LPASPPLQT-------SLSPAVSPLSSPL 484
Query: 538 SAHILSAAPIQVGQPALFQMPVS-LAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAML 596
+ H L A Q P+S L L TQS AP P+ T +T PP L
Sbjct: 485 TIHPLQALSSLASHSP--QAPLSSLIMPPLETQSSLAP--PSLQTPPASLTTPP-----L 535
Query: 597 NTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA 656
L P A+ P L P P P + P PL P+ P TP
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET--PSSIATPPPQ 593
Query: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
APP +P P GL S P + PP A P L P L
Sbjct: 594 APPALASP-PLQGLPSPPLSPLATPPPQAPPXLAL----------------------PPL 630
Query: 717 SVPASVIVSAP-PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP-GPS 774
P S S P P P+P P A L QAP S P+P Q P + P P PS
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPP-PSPPVQAPFSPPASPPVSPS 688
Query: 775 SSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSR--PPSEPPLHPCPPPQAPPTLP 832
++P P QAP P L +P PPS P S P S S PP PP PP Q PP+ P
Sbjct: 689 ATP--PSQAP----PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742
Query: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892
+ PPP P AP PP P S P P P PP+ + + +
Sbjct: 743 ASPPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 893 ETSSRLPAPTPSD-------FQLQFPPSQGPH-------KSPTPPPTLHLVPEPAAPPPP 938
+ P P L PP Q P + P PP + P PP P
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Query: 939 PPRT------FQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLG 990
P T + P P P ++ SG L + A + P+ G
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTL----SGPDLAGHSSSATSTPEELRGYDSG 917
Query: 991 PLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLP----PLLPAENKAFASNLPTLN 1046
P AAS + + P A S PAP P+A G P P PA A L T+
Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIY 976
Query: 1047 VAKAASSGPGKPSGL 1061
+ S P L
Sbjct: 977 ETEGPESATPAPGAL 991
Score = 123 bits (309), Expect = 1e-27
Identities = 206/768 (26%), Positives = 279/768 (36%), Gaps = 134/768 (17%)
Query: 154 AGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPG 213
A P + P S +Q PP++ T + P + + +L P P+ L + LQ
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP--SPLALSS--LQATTS 417
Query: 214 LQGLPNGSPG-GATAATLGLAPIQV---VGQPVMALNTPTSQ-------LLAKQVPVSGY 262
L GSP AT + L ++P Q + P +TP L P+
Sbjct: 418 L-----GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472
Query: 263 LASAAGP-SEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPS 321
L+ A P S P+T+ A Q LS+ + L S + P +
Sbjct: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 322 GQPLAVAPGLGSSPL--VPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLT 379
PL P L PL AP H TP P P + P TP P P+
Sbjct: 533 -PPLENLPSLAPPPLQTASAPLTTPH-LETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Query: 380 IQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA----- 434
P AL P L G P+P L P A A
Sbjct: 591 PPQAPPALASPP-------------------LQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 435 APPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVG 494
APP PP S P+S + A H+L Q F P +P VQ P A P
Sbjct: 632 APPSPPA--SPPLSPLATPSPQAPNALAVHLL--QAPFSPPPSPPVQAPFSPPASPP--- 684
Query: 495 GQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
+ +A P P +LA P P P S S SA P
Sbjct: 685 --VSPSATP---------PSQAPPSLAAPPLQVPPSPPASPPMSP---SATPPP------ 724
Query: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
Q P LAA P Q P+P PA+ + T PP +L P V P+ PA+
Sbjct: 725 -QAPPPLAAP--PLQVPPSP--PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-- 777
Query: 615 AAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAP-TPQAAAP--PQATTPQPSPGLA 671
+P+ +P PQAPPA++TP L P A P QAP +P A+ P P AT P +P +
Sbjct: 778 MSPL--AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
++P V PP A+PT LQ S GP L++ + PPP
Sbjct: 836 AAPLLQVPPSPP-ASPT-------LQAPRRPPTPGPDTSVSGPRLTL---ALAPGPPPPP 884
Query: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+P++ ++ GP +S P+ GP ++ S P A L
Sbjct: 885 SRSPSSTLS-----GPDLAGHSSSATSTPEELRGYD-SGPEGGAAASPPPDAELA----- 933
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
+ HP SR P+ P + P P P PP P + G+ I G P ++ PA
Sbjct: 934 -ACHPAAW-SRGPAPPLAFRGAPGAPL--PWPPATGPGSADGLCTIYETEG--PESATPA 987
Query: 852 PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899
P G L P P S +A + + SSR P
Sbjct: 988 P------------------GALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
Score = 123 bits (308), Expect = 2e-27
Identities = 208/814 (25%), Positives = 279/814 (34%), Gaps = 199/814 (24%)
Query: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
+ P A G P+PPG+ P V P + L GA +
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPV----------------TPAALRVL--GAAGAVGRK 56
Query: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP-------------LSLGPVLA 531
L+ +GG + +AP G A N P S GPV +
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
Query: 532 PHS----------GAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATT 581
P G I + + G+ +L+AG+ S P P P+
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 582 VLQGVTLPPSAVAMLNTPDGLVQPAT--PAAATGEAAPVLTVQPAPQA---PPA------ 630
+ P +P T P + A+ T +P+P A P A
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 631 --------VSTPL-------PLGLQQPQAQQPPQAPTP---QAAAPPQATTPQPSPGLAS 672
+TPL P P+A P P P QA PPQ T P+ A
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
P L P ATP+ T+ + P + + PL A ++P S ++ P P
Sbjct: 297 GP----LSSSPLATPSPSGTK--ARPVPPPDNAATPLPA-----TLPPSPPLATPLPLAP 345
Query: 733 PAPATPVAKGAGLGPQA-PDSQASPA-------PAPQIPAAAPLKGPGPSSSPSLPHQAP 784
P+P+ P + P A P SQA P+ P + P++ P +SPSL QAP
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL--QAP 403
Query: 785 --------------LGDSPHLP--------SPHPTRPPSRPPSRPQSVSRPPSEPPLH-- 820
LG SP L SP T+ PSRP S PP PPL
Sbjct: 404 PSPLALSSLQATTSLG-SPTLQATHSFLTMSPRQTQASLTSPSRP--ASTPPDSPPLQAP 460
Query: 821 ---PCPPPQAPPTLPGIFVIQNQLGVPP--PASNPAPTAPGPP-----QPPLRPQSQ--P 868
P PP P + + + L + P S+ A +P P PPL QS P
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
Query: 869 PEGPLPPA----------PHL--PPSSTSSAVASSSETSSRLPAPTPSDFQ-----LQFP 911
P PPA P L PP T+SA ++ + P P P Q L P
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP-PCPAPCPLQAPPSPLTTP 579
Query: 912 PSQGPHKSPTPP---------PTLHLVPEPAAPP---PPPPRTFQMVTTPFPALPQPKA- 958
P + P TPP P L +P P P PPP + P A P P A
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 959 -----LLERFHQVPSGIILQ----------NKAGGAPAAPQTSTSLGPLTSP-------- 995
L Q P+ + + + AP +P S + P +P
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699
Query: 996 -AASVLVSGQAPSGTPTAPSHAP---APAPMAATGL--PPLLPAENKAFAS-----NLPT 1044
A + V P+ P +PS P AP P+AA L PP PA S +P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Query: 1045 LNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQP 1078
L A P P+ L +S L KPP P
Sbjct: 760 LLAAPPLQVPPSPPASL----PMSPLAKPPPQAP 789
Score = 117 bits (294), Expect = 7e-26
Identities = 245/1038 (23%), Positives = 340/1038 (32%), Gaps = 212/1038 (20%)
Query: 553 ALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT 612
A + P + A G L + +P P T P+A+ +L G V A
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVT--------PAALRVLGAA-GAVGRKPLAERA 62
Query: 613 GEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLAS 672
G + AP+A P S + A +PP + + A P + T SPG S
Sbjct: 63 GGIGGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNT----SPGPVS 115
Query: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
SP G+ T L Q L++ +E + + E P S ++ A
Sbjct: 116 SP-----GRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRS---ALSAGARRDTSG 166
Query: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
P P TP A A P PAP P +GP S S + H S P
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH------STTEP 220
Query: 793 SPHPTRPPS------RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP 846
SP R PS RP SR S S P P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSP---------------------------- 252
Query: 847 ASNPAPTAPGPPQPPLRPQSQPPEG--PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
+ P+A G P+ P P P+G L P P + P +A A +SS L P+PS
Sbjct: 253 -ARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 905 DFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFH 964
G P PPP P PA PP PP + TP P
Sbjct: 311 ----------GTKARPVPPPDNAATPLPATLPPSPP-----LATPLPL------------ 343
Query: 965 QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAA 1024
AP +P SL L SP A+ PS P + + P AP +
Sbjct: 344 --------------APPSPSAPPSLQTLPSPPAT------PPSQAPPSMTTPPMQAPPSL 383
Query: 1025 TGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACF 1084
+PP+ + P+L A P S LQ + L PTLQ +
Sbjct: 384 QTIPPI----QVPHSLTSPSLQ----APPSPLALSSLQATTSLGS----PTLQATHSFLT 431
Query: 1085 LEHLHKHQGSVLHPDYKTAFPSFEDALHRLL------PYHVYQGALPSPSDYHKVDEEFE 1138
+ + Q S+ P + P L L P SP +
Sbjct: 432 MSP-RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 1139 TVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALD--KQLAKE 1196
+S+ QA L+ + LE ++P + +Q +L + L
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPS---------LQTPPASLTTPPLENLPSL 541
Query: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVI---RHGGA 1253
P ++S L P E P PL + P T PPP P+ + + A
Sbjct: 542 APPPLQTASAPLTTP---HLETPPCPAPCPLQAP-PSPLTTPPPETPSSIATPPPQAPPA 597
Query: 1254 GGSPSVTWARAS--SSLSSSSSSSSAASSLDADEDGPMPSRNRP--PIKTYEARSRIGLK 1309
SP + + S L++ + +L + P P + P P+ T ++ L
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
Query: 1310 LKIKQE--------------------------AGLSKVVHNTALDPVHQPPPPPATLKVA 1343
+ + Q S+ + A P+ PP PPA+ ++
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 1344 EPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEG 1403
PP PPP V PPA+P P T P PR+P P P
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP--PRVPPLLAAPPLQVPPSPPAS 775
Query: 1404 TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDE--------LYQRMLKGPPPE-PAAS 1454
P P PA L A+ + L L PPP+ P
Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 1455 AAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQA 1514
AA P + P PPA SP + QA +P DT S L L A
Sbjct: 836 AA-----PLLQVPPSPPA------SPTL-QAPRRPPTPGPDT------SVSGPRLTLALA 877
Query: 1515 PGRTPAPSYPHAASAGTP 1532
PG P PS +++ P
Sbjct: 878 PGPPPPPSRSPSSTLSGP 895
Score = 89.4 bits (220), Expect = 3e-17
Identities = 205/876 (23%), Positives = 282/876 (32%), Gaps = 178/876 (20%)
Query: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
+A P L P PPP PA + +G + +A IP +AP
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPP 829
GP S+ S P SRPP+ + PP++ + P P + P
Sbjct: 78 GPTRSAGTS-----------------SRNPASRPPASGRGERAPPAK---NTSPGPVSSP 117
Query: 830 ------TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS----QPPEGPLPPAPHL 879
T PG Q G+ A P S + GP P P
Sbjct: 118 GRASGTTRPGPL---GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-- 172
Query: 880 PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPP 939
P+ + A+ +E LP P PS PP++GP KS +
Sbjct: 173 SPAMARRSRAAGTEVG--LPRPAPS--ARPRPPTEGPRKSVS------------------ 210
Query: 940 PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGA---PAAPQTSTSLGPLTSPA 996
+ T P PA + + AGG PA+ S+S PL+SPA
Sbjct: 211 SASEHSTTEPSPAARR-----------------RPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 997 ASVLVSGQAPSGTPTAPSHAPAPAPMAATGL-PPLLPAENKAFASNLPTLNVAKAASSGP 1055
SG + GTP AP+H P P L PP + K A L L+ + A+ P
Sbjct: 254 R----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 1056 GKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLL 1115
SG K P P A L + L P A P L
Sbjct: 310 ------------SGTKARPVPPPDNAATPLP-------ATLPPSPPLATP---------L 341
Query: 1116 PYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMI 1175
P A PSPS + +T + +M + + + P +
Sbjct: 342 PL-----APPSPSAPPSLQTLPSPPATPPSQAPPSMTTP-PMQAPPSLQTIPPIQVPHSL 395
Query: 1176 DRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGH--RLPGHGPLSSSAPG 1233
+Q + LAL + ++ SLG P ++ P S ++P
Sbjct: 396 TSPSLQAPPSPLALSS----------LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445
Query: 1234 ASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSS--SSSSSSAASSLDA-DEDGPMP 1290
PP P A + + A S LSS + A SSL + P+
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
Query: 1291 SRNRPPIKTYEARSRIGLKL--------KIKQEAGLSKVVHNTALDPVHQP----PPPPA 1338
S PP++T + + L+ ++ L+ TA P+ P PP PA
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565
Query: 1339 TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP---ERKPLGTAPHCPRLPLRKTYRENV 1395
+ PP PPP T T PPP AP PL P P PL
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIAT---PPPQAPPALASPPLQGLPSPPLSPLAT------ 616
Query: 1396 GGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASA 1455
P P A AP S L + L +L+ P P +
Sbjct: 617 ----PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-- 670
Query: 1456 AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
P +AP PPA SP V ++ LQ + +P
Sbjct: 671 ------PPVQAPFSPPA------SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 1516 GRTPAPSYPHAASA---GTPASPP--PLHRPEAYPP 1546
TP P P +A P SPP P P A PP
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 85.9 bits (211), Expect = 3e-16
Identities = 208/851 (24%), Positives = 282/851 (33%), Gaps = 159/851 (18%)
Query: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP-GPSSSPSLPHQAPLGDSPHLP 792
A TP A+ GL P P P P PAA + G G L +A +P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 793 SPHPTRPPSRPP--SRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
P P+R S SRPP+ PP A T PG V P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP--AKNTSPG--------PVSSPGRAS 121
Query: 851 APTAPGP-PQPPLRPQSQPP--EGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDF 906
T PGP Q LR ++ G AP SA+++ + + P P TPS
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPK------RSALSAGARRDTSGPTPGTPSPA 175
Query: 907 QLQFPPSQGPHKS-PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
+ + G P P P+ P P P ++ + P P A +
Sbjct: 176 MARRSRAAGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAA-----RR 226
Query: 966 VPSGIILQNKAGGA---PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPM 1022
PS AGG PA+ S+S PL+SPA S G + GTP AP+H P P
Sbjct: 227 RPS-------AGGGLQRPASRSLSSSATPLSSPARS----GPSARGTPRAPAHPSQPKPK 275
Query: 1023 AATGL-PPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
L PP + K A L L+ + A+ P SG K P P
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP------------SGTKARPVPPPDNA 323
Query: 1082 ACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVS 1141
A L + L P A P LP A PSPS + +
Sbjct: 324 ATPLP-------ATLPPSPPLATP---------LPL-----APPSPSAPPSLQTLPSPPA 362
Query: 1142 TQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEY 1201
T + +M + + + P + +Q + LAL
Sbjct: 363 TPPSQAPPSMTTP-PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS---------- 411
Query: 1202 VSSSRSLGLPIAASSEGHRL--PGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSV 1259
+ ++ SLG P ++ P S ++P PP P A
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471
Query: 1260 TWARASSSLSSSSSSS--SAASSLDADE-DGPMPSRNRPPIKTYEARSRIGLKLK----- 1311
+ + A S LSS + A SSL + P+ S PP++T + + L+
Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531
Query: 1312 ---IKQEAGLSKVVHNTALDPVHQP----PPPPATLKVAEPPPRPPPPPPPTGQMNGTVD 1364
++ L+ TA P+ P PP PA + PP PPP T T
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT-- 589
Query: 1365 HPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEA 1424
PPP AP P +P LP P +P TP +A P
Sbjct: 590 -PPPQAP---PALASPPLQGLP---------SPPLSPLATPPPQAPPXLALP-------- 628
Query: 1425 TSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPG-----LPPAKRRKSES 1479
L+ PP PA+ P +AP L A S
Sbjct: 629 ------------------PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 1480 PDVDQASFS--SDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
P V QA FS + P + T Q+ Q P PA ++ P +PPP
Sbjct: 671 PPV-QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 1538 LHRPEAYPPSS 1548
L P P S
Sbjct: 730 LAAPPLQVPPS 740
Score = 55.5 bits (132), Expect = 4e-07
Identities = 65/237 (27%), Positives = 82/237 (34%), Gaps = 53/237 (22%)
Query: 1326 ALDPVHQPPPPPATLKV---AEPPPRPPPP---------PPPTGQMNGTVDHPPPAAPER 1373
A P+ PP PPA+L + A+PPP+ PP P P G P A+
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821
Query: 1374 KPLGT----APHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI 1429
PL T AP PL + P +P +P +A P P P D + SG
Sbjct: 822 SPLATPPPQAPPVLAAPLLQV-------PPSPPASPTLQAPRRPPTPGP---DTSVSGPR 871
Query: 1430 RELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW-----EAPGLPPAKRRKSESPDVDQ 1484
LA + GPPP P+ S + PD A P R P+
Sbjct: 872 LTLA---------LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 922
Query: 1485 ASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP 1541
A+ SP D A A R PAP + G P PP P
Sbjct: 923 AA----SPPPDAELAACHPA---------AWSRGPAPPLAFRGAPGAPLPWPPATGP 966
Score = 34.3 bits (77), Expect = 0.97
Identities = 61/251 (24%), Positives = 84/251 (33%), Gaps = 35/251 (13%)
Query: 1222 PGHGPLSSSAPGASTQP-PPHLPTKLVIRHGGAGG-SPSVTWARASSSLSS------SSS 1273
P P +AP P PP PT R G SV+ R + +L+ S S
Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
Query: 1274 SSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQP 1333
SS S D + ++ Y++ G +A L+ H A +
Sbjct: 888 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA-ACHPAAWS---RG 943
Query: 1334 PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRE 1393
P PP + A P P PP G +G PE T
Sbjct: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE---------------SATPAP 988
Query: 1394 NVGGPGAPEGTPAGRARGG------SPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
PG GT G+A G S +P A++ E G ++ A+V L R L
Sbjct: 989 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ--ASVVQHLLSRTLLLA 1046
Query: 1448 PPEPAASAAQG 1458
E AA + G
Sbjct: 1047 AAEGAAGGSGG 1057
>gi|54792088 hypothetical protein LOC23506 [Homo sapiens]
Length = 1079
Score = 157 bits (398), Expect = 6e-38
Identities = 158/527 (29%), Positives = 227/527 (43%), Gaps = 77/527 (14%)
Query: 775 SSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH-PCPPPQAPPTLPG 833
+S S P + +G PH+ + +R P Q+VS +H P P AP +
Sbjct: 345 ASASSPQGSVVG--PHMSVNIVNQQNTRKPVTSQAVSSTGGSIVIHSPMGQPHAPQSQ-- 400
Query: 834 IFVIQNQLGVPPPASNPAPTAPGP-----PQPPLRPQ------------------SQPPE 870
F+I L V + + T G P + Q +QP
Sbjct: 401 -FLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYT 459
Query: 871 GPL----PPAPHLPPSSTSSAV--------ASSSETSSRLPAPTPSDFQLQFPPSQGPHK 918
GP+ A HL T +A AS ++P S L P Q
Sbjct: 460 GPMLNNQNTAVHLVSGQTFAASGSPVIANHASPQLVGGQMPLQQASPTVLHLSPGQSSVS 519
Query: 919 SPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLE--------------RFH 964
P P+ P F V++ A P + ++ + +
Sbjct: 520 QGRPG----FATMPSVTSMSGPSRFPAVSSASTAHPSLGSAVQSGSSGSNFTGDQLTQPN 575
Query: 965 QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAP------- 1017
+ P + + ++ + + ++ S P T Q T+P AP
Sbjct: 576 RTPVPVSVSHRLPVSSSKSTSTFSNTPGTGTQQQFFCQAQKKCLNQTSPISAPKTTDGLR 635
Query: 1018 -APAPMAATGLPPLLPAENKAFASNLPTLNVA--KAASSGPGKPSGLQYESKLSGLKKPP 1074
A P + P + +K +++L T K S PG P+ +Q ES G K+P
Sbjct: 636 QAQIPGLLSTTLPGQDSGSKVISASLGTAQPQQEKVVGSSPGHPA-VQVESHSGGQKRPA 694
Query: 1075 TLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVD 1134
Q +K A L+ L + Q + PD K+ F S DA+ RLL YHV QG++P+ D KVD
Sbjct: 695 AKQLTKGAFILQQLQRDQAHTVTPD-KSHFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVD 753
Query: 1135 EEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLA 1194
EFETV+TQLLKRTQAMLNKYR LLLE++ R++PSAEMVMIDRMF QEE+ +L+ DK+LA
Sbjct: 754 NEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLA 813
Query: 1195 KEKPDEYVSS-SRSLGLPIAA-SSEGHRLPGHGPLSSSAPGASTQPP 1239
P+ + + S L AA ++ R HG +SS S QPP
Sbjct: 814 LVDPEGFQADFCCSFKLDKAAHETQFGRSDQHGSKASS----SLQPP 856
Score = 118 bits (295), Expect = 5e-26
Identities = 184/681 (27%), Positives = 267/681 (39%), Gaps = 136/681 (19%)
Query: 1 MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDNPG----EAQSAFYEGPGLHVQ-- 54
MDD+D CLLD+I DPQALN FLHG S+D L N G + S F +
Sbjct: 1 MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNDDLTNAGYSAANSNSIFANSSNADPKSS 60
Query: 55 -EASGNHLNPEPNQPAP-SVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEAN 112
+ N L P+ P S L FLED++ SP DQP DILQ+SLQEAN
Sbjct: 61 LKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLP------DLTEDQPFDILQKSLQEAN 114
Query: 113 ITEQTLEAEAELD--LGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQ 170
ITEQTL EA LD +G Q Q A P+ + A+ A + + G T LQ
Sbjct: 115 ITEQTLAEEAYLDASIGSSQ----QFAQAQLHPSSS--ASFTQASNVSNYSGQT----LQ 164
Query: 171 GPPTVLTHQALVPPQDVVNKALSVQ-PFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAAT 229
P +TH + + + VQ F+Q VG+ +P Q L N S
Sbjct: 165 --PIGVTHVPV--GASFASNTVGVQHGFMQHVGIS------VPS-QHLSNSS------QI 207
Query: 230 LGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVI 289
G IQ++G + S + + S + +G P S GL++
Sbjct: 208 SGSGQIQLIG----SFGNHPSMMTINNLDGSQIILKGSGQQAP--------SNVSGGLLV 255
Query: 290 QKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVA-PGLGSSPLVPAPNVILHR-- 346
+ T NGNS+FG + + +P QP+ V +P N+I+ R
Sbjct: 256 HRQ-------TPNGNSLFGNS------SSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGL 302
Query: 347 ------TPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFM 400
P IQPKP + Y + L I QQ Q ++F
Sbjct: 303 APNSNKVPINIQPKPIQMGQQNTYNVN---------NLGI--------QQHHVQQGISFA 345
Query: 401 AAGKAGQNVVLSGFPAPALQANVFKQ----PPATTTGAAPP-------QPPGALSKPMSV 449
+A +VV P + N+ Q P T+ + P G P S
Sbjct: 346 SASSPQGSVV-----GPHMSVNIVNQQNTRKPVTSQAVSSTGGSIVIHSPMGQPHAPQSQ 400
Query: 450 HLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSA---LPANVGGQILAAAAPHTG 506
L+ S+ + H + N LL P+ + Q+++ + +L P+TG
Sbjct: 401 FLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYTG 460
Query: 507 GQLIANPILTNQNLAGPLSLG--------PVLAPHSGAHSAHILSAAPIQVGQPALFQMP 558
P+L NQN A L G PV+A H A + P+Q P + +
Sbjct: 461 ------PMLNNQNTAVHLVSGQTFAASGSPVIANH--ASPQLVGGQMPLQQASPTVLHLS 512
Query: 559 VSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE--AA 616
++ S Q +P A + T + G + P AV+ +T + A + ++G
Sbjct: 513 PGQSSVS---QGRPGFATMPSVTSMSGPSRFP-AVSSASTAHPSLGSAVQSGSSGSNFTG 568
Query: 617 PVLTVQPAPQAPPAVSTPLPL 637
LT P +VS LP+
Sbjct: 569 DQLTQPNRTPVPVSVSHRLPV 589
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 145 bits (367), Expect = 2e-34
Identities = 203/744 (27%), Positives = 270/744 (36%), Gaps = 182/744 (24%)
Query: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
+ P A G P+PPG+ P V P + L GA +
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPV----------------TPAALRVL--GAAGAVGRK 56
Query: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP----LSLGPVLAPHS------ 534
L+ +GG + +AP G + P + + P S GPV +P
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 116
Query: 535 ----GAHSAHILSAAPIQVGQPALFQMPVSLAAG-----SLPTQSQPAPA---------- 575
G I + + G+ +L+AG S PT P+PA
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 576 ------------------GP--AATTVLQGVTLPPSAVAMLNTPDG----------LVQP 605
GP + ++ + T PS A G L
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 606 ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP------ 659
ATP ++ + P + + P+AP S P P GL QA +PPQ P+ A P
Sbjct: 237 ATPLSSPARSGP--SARGTPRAPAHPSQPKPKGL---QALRPPQVTPPRKDAAPALGPLS 291
Query: 660 --QATTPQPS--PGLASSPEKIVLGQPPSATPTAILTQ------DSLQMFLPQERSQQPL 709
TP PS P ++ P L PP+ P+ T + FLP PL
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP----SPPL 347
Query: 710 S--AEGPHLSVPASVI--VSAPPPAQDPAPATPVAKGAGLGPQAPDS------QASPAPA 759
S A P + PA + + APP P +P+A + PQAP++ QA +P
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS---PQAPNALAVHLLQAPFSPP 404
Query: 760 PQIPAAAPLKGP-GPSSSPSL--PHQAPLGDSPHLPSPH---PTRPPSRPPSRPQSVSRP 813
P P AP P P SPS P QAP P L +P P PP+ PP P + P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAP----PSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 814 PSEPPLH------PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ 867
+ PPL PPPQAPP L PP + P+P A P Q P P +
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPA----------LATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 868 PPEGPL-PPAPHLPP--SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP 924
P PL P P PP ++ V S S L AP + PP+ GP S + P
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP-------RRPPTPGPDTSVSGPR 563
Query: 925 -TLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
TL L P PPPPP R+ P + L SG L + A + P
Sbjct: 564 LTLALAP---GPPPPPSRS-------------PSSTL-------SGPDLAGHSSSATSTP 600
Query: 984 Q--TSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLP----PLLPAENKA 1037
+ GP AAS + + P A S PAP P+A G P P PA
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPG 659
Query: 1038 FASNLPTLNVAKAASSGPGKPSGL 1061
A L T+ + S P L
Sbjct: 660 SADGLCTIYETEGPESATPAPGAL 683
Score = 139 bits (349), Expect = 3e-32
Identities = 215/805 (26%), Positives = 301/805 (37%), Gaps = 162/805 (20%)
Query: 346 RTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA 405
R P + P+P G P P P PA L + G GA+ ++P A + A G
Sbjct: 20 RAPGLLTPRPPGSPRP------PPPVTPAA--LRVLGAAGAVGRKPLAER-----AGGIG 66
Query: 406 GQNVVLSGFPA-------PALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSI 458
G + S A P + PPA T P PG S L Q
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126
Query: 459 VIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQ 518
+ + + G+ A + P++ SAL A G + P G +P + +
Sbjct: 127 ISAEETVARGK---------ATEAPKR-SALSA---GARRDTSGPTPG---TPSPAMARR 170
Query: 519 NLAGPLSLG-PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGP 577
+ A +G P AP SA P +P S+++ S + ++P+PA
Sbjct: 171 SRAAGTEVGLPRPAP----------SARP----RPPTEGPRKSVSSASEHSTTEPSPAAR 216
Query: 578 AATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL 637
+ G+ P S L ATP ++ + P + + P+AP S P P
Sbjct: 217 RRPSAGGGLQRPASR--------SLSSSATPLSSPARSGP--SARGTPRAPAHPSQPKPK 266
Query: 638 GLQQPQAQQPPQAPTPQAAAPPQA--------TTPQPS--PGLASSPEKIVLGQPPSATP 687
GLQ A +PPQ P+ A P TP PS P ++ P L PP+ P
Sbjct: 267 GLQ---ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323
Query: 688 TAILTQ------DSLQMFLPQERSQQPLS--AEGPHLSVPASVI--VSAPPPAQDPAPAT 737
+ T + FLP PLS A P + PA + + APP P +
Sbjct: 324 SQATTSLGSPTLQATHSFLPSP----PLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379
Query: 738 PVAKGAGLGPQAPDS------QASPAPAPQIPAAAPLKGPG-PSSSPSL--PHQAP---- 784
P+A + PQAP++ QA +P P P AP P P SPS P QAP
Sbjct: 380 PLATPS---PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436
Query: 785 ---LGDSPHLP-----SPHPTRPPSRPP---SRPQSVSRPPSE-------PPLHPCPPPQ 826
L P P SP T PP PP + P +++PP + PPL P P
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
Query: 827 A-----PPTLPGIFVIQNQLGVPPPASNP---APTAPGPPQPPLRPQSQPPEGP------ 872
A P P + + L PPP + P AP PP PP P Q P P
Sbjct: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556
Query: 873 -----------LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH--KS 919
L P P PPS + S+ S + + + T + +L+ S GP +
Sbjct: 557 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAA 615
Query: 920 PTPPPTLHLV---PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKA 976
+PPP L P + P PP F+ P LP P A G+ +
Sbjct: 616 ASPPPDAELAACHPAAWSRGPAPPLAFR--GAPGAPLPWPPA---TGPGSADGLCTIYET 670
Query: 977 GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT-APSHAPAPAPMAATGLPPLLPAEN 1035
G +A +L P SP S G+A +G A S +P A + L L +
Sbjct: 671 EGPESATPAPGALDPGPSPGTS---GGKAAAGAGAGASSRSPKQARLGELPLGALQASVV 727
Query: 1036 KAFASNLPTLNVAKAASSGPGKPSG 1060
+ S L A+ A+ G G G
Sbjct: 728 QHLLSRTLLLAAAEGAAGGSGGGPG 752
Score = 85.1 bits (209), Expect = 5e-16
Identities = 195/799 (24%), Positives = 262/799 (32%), Gaps = 117/799 (14%)
Query: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
+A P L P PPP PA + +G + +A IP +AP
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPP------SRPPSRPQSVSRPPSEPPLHPCP 823
GP +S P + SP P P +RP Q R +E +
Sbjct: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP------EGPLPPA- 876
+AP ++ L PT PG P P + +S+ P P A
Sbjct: 138 ATEAPK--------RSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 877 PHLPPSSTSSAVASSSETSSRLPAPT-----PSDFQLQFPPSQGPHKSPTP-------PP 924
P P +V+S+SE S+ P+P + LQ P S+ S TP P
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 925 TLHLVPE-PAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
+ P PA P P P+ Q + P P+ A APA
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA--------------------APALG 288
Query: 984 QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGL-PPLLPAENKAFASNL 1042
S+S PL +P+ S S AP T PS P A T L P L A + S L
Sbjct: 289 PLSSS--PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH----SFL 342
Query: 1043 PTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKT 1102
P+ ++ A+ P P L L L+ PP+ S L P T
Sbjct: 343 PSPPLSPLATPPPQAPPAL----ALPPLQAPPSPPASPP--------------LSP-LAT 383
Query: 1103 AFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEE 1162
P +A L H+ Q SP V F ++ + + ++ L
Sbjct: 384 PSPQAPNA----LAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438
Query: 1163 SRRVSP----SAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLP--IAASS 1216
+V P S M Q A QLAK P + +L P A S
Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQALPS 494
Query: 1217 EGHRLPGHGPLSSSA-----PGASTQP--PPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269
PG P S SA P A+ P PP L L+ SP++ R +
Sbjct: 495 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 554
Query: 1270 SSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDP 1329
+S S +L A GP P +R P T G + +
Sbjct: 555 PDTSVSGPRLTL-ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613
Query: 1330 VHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHC----PRL 1385
PPP A L P P PP G P P P P C
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 1386 PLRKTYRENVGGPGAPEGTPAGRARGG------SPAPLPAKVDEATSGLIRELAAVEDEL 1439
P T PG GT G+A G S +P A++ E G ++ A+V L
Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ--ASVVQHL 730
Query: 1440 YQRMLKGPPPEPAASAAQG 1458
R L E AA + G
Sbjct: 731 LSRTLLLAAAEGAAGGSGG 749
Score = 77.8 bits (190), Expect = 8e-14
Identities = 100/358 (27%), Positives = 131/358 (36%), Gaps = 56/358 (15%)
Query: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPS--SSPSLPHQAPLGDSPHL 791
A TP A+ GL P P P P PAA + G + P +G +
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRP-PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA--- 68
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
T P S P + P SRPP+ PP A T PG V P
Sbjct: 69 -----TIPESAPRAGPTRTSRPPASGRGERAPP--AKNTSPG--------PVSSPGRASG 113
Query: 852 PTAPGP-PQPPLRPQSQP--PEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQ 907
T PGP Q LR ++ G AP SA+++ + + P P TPS
Sbjct: 114 TTRPGPLGQKGLRISAEETVARGKATEAP------KRSALSAGARRDTSGPTPGTPSPAM 167
Query: 908 LQFPPSQGPHKS-PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQV 966
+ + G P P P+ P P P ++ + P P A +
Sbjct: 168 ARRSRAAGTEVGLPRPAPS----ARPRPPTEGPRKSVSSASEHSTTEPSPAA-----RRR 218
Query: 967 PSGIILQNKAGGA---PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
PS AGG PA+ S+S PL+SPA SG + GTP AP+H P P
Sbjct: 219 PS-------AGGGLQRPASRSLSSSATPLSSPAR----SGPSARGTPRAPAHPSQPKPKG 267
Query: 1024 ATGL-PPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSK 1080
L PP + K A L L+ + A+ P P L L PP PS+
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325
Score = 67.8 bits (164), Expect = 8e-11
Identities = 162/725 (22%), Positives = 228/725 (31%), Gaps = 110/725 (15%)
Query: 847 ASNPAPTAPG--PPQPPLRPQSQPPEGPLP--------PAPHLPPSSTSSAVASSSETSS 896
A PA APG P+PP P+ PP P P + + + ++ S
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 897 RLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQP 956
AP + PP+ G + PP + P P + P T T P P L Q
Sbjct: 74 ---APRAGPTRTSRPPASG--RGERAPPAKNTSPGPVSSPGRASGT----TRPGP-LGQK 123
Query: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA 1016
+ V G + A +A + GP + + +GT
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG---L 180
Query: 1017 PAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTL 1076
P PAP A P P ++ + AS T + AA P S GL++P +
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP---------SAGGGLQRPASR 231
Query: 1077 QPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEE 1136
S A L + S A PS P P +
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPS-----------------QPKPKGLQALRPP 274
Query: 1137 FETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKE 1196
T + L+ L S SPSA + + L
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL----------------QTLPSP 318
Query: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGS 1256
++ SLG P ++ H PLS A PPP P L + A S
Sbjct: 319 PATPPSQATTSLGSPTLQAT--HSFLPSPPLSPLAT-----PPPQAPPALALPPLQAPPS 371
Query: 1257 PSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEA 1316
P + + + S + ++ A L P PS PP++ S
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS---PPVQA--PFSPPASPPVSPSAT 426
Query: 1317 GLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP---ER 1373
S+ + A P+ PP PPA+ ++ PP PPP + PPP AP
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486
Query: 1374 KPLGTAPHCP-RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPL----PAKVDEATSGL 1428
PL P P P + + + P +P TP +A APL P+ T
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Query: 1429 IR-------ELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW-----EAPGLPPAKRRK 1476
R + + L + GPPP P+ S + PD A P R
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Query: 1477 SESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPP 1536
P+ A+ SP D A A R PAP + G P P
Sbjct: 607 DSGPEGGAAA----SPPPDAELAACHPA---------AWSRGPAPPLAFRGAPGAPLPWP 653
Query: 1537 PLHRP 1541
P P
Sbjct: 654 PATGP 658
Score = 56.6 bits (135), Expect = 2e-07
Identities = 96/364 (26%), Positives = 130/364 (35%), Gaps = 104/364 (28%)
Query: 1203 SSSRSLGLPIAASSEGHRLPGHGP---LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSV 1259
++ +GLP A S R P GP +SS++ ++T+P P R AGG
Sbjct: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRPSAGGG--- 224
Query: 1260 TWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLS 1319
AS SLSSS++ S+ P+R+ P +
Sbjct: 225 LQRPASRSLSSSATPLSS------------PARSGPSAR--------------------- 251
Query: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379
T P H P P L+ PP PP AAP PL ++
Sbjct: 252 ----GTPRAPAHPSQPKPKGLQALRPPQVTPP--------------RKDAAPALGPLSSS 293
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P P P +P P+ + PA P+ +AT+ L + +
Sbjct: 294 PLATPSP---------SAPPSPSAPPSLQTLPSPPATPPS---QATT----SLGSPTLQA 337
Query: 1440 YQRMLKGPPPEPAAS----AAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQ-D 1494
L PP P A+ A P +AP PPA SP + + ++ SPQ
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA------SPPL--SPLATPSPQAP 389
Query: 1495 DTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLG 1554
+ L H L QAP +P PS P A PASPP P A PPS L
Sbjct: 390 NALAVH----------LLQAP-FSPPPSPPVQAPFSPPASPPV--SPSATPPSQAPPSLA 436
Query: 1555 ARTL 1558
A L
Sbjct: 437 APPL 440
Score = 53.9 bits (128), Expect = 1e-06
Identities = 132/504 (26%), Positives = 175/504 (34%), Gaps = 68/504 (13%)
Query: 118 LEAEAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQG--PPTV 175
L+ A L P PA G G A A + P+ GLQ PP V
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK--------GLQALRPPQV 276
Query: 176 LTHQALVPPQDVVNKAL---SVQPFLQPVGLGNVTLQPIPGLQGLPN--GSPGGATAATL 230
PP+ AL S P P + P LQ LP+ +P +L
Sbjct: 277 ------TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330
Query: 231 GLAPIQVV-----GQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGA 285
G +Q P+ L TP Q + + A + P+ P A SPQ
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQA-PPALALPPLQAPPSPPASPPLSPLATPSPQAP 389
Query: 286 GLVIQKNLSAAVATTLNGNSVFGGAGAAS---APTGTPSGQ--PLAVAPGLGSSPLVPA- 339
+ L A + + + AS +P+ TP Q P AP L P PA
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 340 PNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQ-------GEPGALPQQPK 392
P + TP P P P PP P PA AT +Q PG P P
Sbjct: 450 PPMSPSATPPPQAPPPLAA-PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 393 APQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPP-----GALSKPM 447
A ++ +A VL+ AP LQ V PPA+ T AP +PP ++S P
Sbjct: 509 ASLPMSPLATPPPQAPPVLA---APLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563
Query: 448 SVHLLNQGSSIVIPAQHMLPGQN----QFLLPGAPAVQLPQQLSALPANVGGQILAAAAP 503
L G P P + A P++L + G AAA+P
Sbjct: 564 LTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG--AAASP 618
Query: 504 HTGGQLIA-NPILTNQNLAGPLSL----GPVL--APHSGAHSAHILSAAPIQVGQPALFQ 556
+L A +P ++ A PL+ G L P +G SA L G +
Sbjct: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678
Query: 557 MPVSLAAGSLP-TQSQPAPAGPAA 579
P +L G P T A AG A
Sbjct: 679 APGALDPGPSPGTSGGKAAAGAGA 702
Score = 48.1 bits (113), Expect = 6e-05
Identities = 88/368 (23%), Positives = 125/368 (33%), Gaps = 67/368 (18%)
Query: 1213 AASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSS 1272
AA + R PG L+ PG+ PPP P L + G AG A + + ++
Sbjct: 13 AARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVL-GAAGAVGRKPLAERAGGIGGAT 69
Query: 1273 SSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQ 1332
SA + GP + +RPP R + NT+ PV
Sbjct: 70 IPESAPRA------GPTRT-SRPPASGRGER---------------APPAKNTSPGPVSS 107
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP-RLPLRKTY 1391
P T + P P GQ + +A E G A P R L
Sbjct: 108 PGRASGTTR-----------PGPLGQKGLRI-----SAEETVARGKATEAPKRSALSAGA 151
Query: 1392 RENVGG--PGAPEGTPAGRARG-----GSPAPLP-AKVDEATSGLIRELAAVEDELYQRM 1443
R + G PG P A R+R G P P P A+ T G + +++ +
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211
Query: 1444 -------------LKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSD 1490
L+ P +S+A P P R + +
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 1491 SPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550
P +T + A ++ L +P TP+PS P + SA P S L P A PPS
Sbjct: 272 RPPQ--VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA--PPSLQTLPSPPATPPSQAT 327
Query: 1551 GGLGARTL 1558
LG+ TL
Sbjct: 328 TSLGSPTL 335
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 140 bits (352), Expect = 1e-32
Identities = 203/772 (26%), Positives = 263/772 (34%), Gaps = 199/772 (25%)
Query: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
+ P A G P+PPG+ P V P + L GA +
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPV----------------TPAALRVL--GAAGAVGRK 56
Query: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP-------------LSLGPVLA 531
L+ +GG + +AP G A N P S GPV +
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
Query: 532 PHS----------GAHSAHILSAAPIQVGQPALFQMPVSLAAG-----SLPTQSQPAPA- 575
P G I + + G+ +L+AG S PT P+PA
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 576 ---------------------------GP--AATTVLQGVTLPPSAVAMLNTPDG----- 601
GP + ++ + T PS A G
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 602 -----LVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA 656
L ATP ++ + P + + P+AP S P P GL QA +PPQ P+
Sbjct: 237 PASRSLSSSATPLSSPARSGP--SARGTPRAPAHPSQPKPKGL---QALRPPQVTPPRKD 291
Query: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
A P SP SP + Q P PT T S + + PL P
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAP---PTLPATPHSSSLTC---QLATPLPLAPPSP 345
Query: 717 SVPASVIVSAPPPAQDPAPAT------------------PVAKGAGLGPQAPDSQA-SPA 757
S P S+ PPA P+ AT P++ A PQAP + A P
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405
Query: 758 PAPQIPAAAPLKGPGPSSSPSLPH-------QAPLGDSPHLPSPHPTRPPSRPPSRP--- 807
AP P A+P P + SP P+ QAP P P P PP+ PP P
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 808 --------------QSVSRPPSEPPLHP--CPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
Q PP+ PP+ P PPPQAPP L + QL PPP + PA
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL---QLAKPPPQAPPA 522
Query: 852 PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
P P P S P + P P+ LP S ++ + L AP LQ P
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV---LAAPL-----LQVP 574
Query: 912 PS-------QGPHKSPTPPP---------TLHLVPEPAAPPPPPPRTFQMVTTPFPALPQ 955
PS Q P + PTP P TL L P PPPPP R+
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP---GPPPPPSRS------------- 618
Query: 956 PKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTPTAP 1013
P + L SG L + A + P+ GP AAS + + P A
Sbjct: 619 PSSTL-------SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671
Query: 1014 SHAPAPAPMAATGLP----PLLPAENKAFASNLPTLNVAKAASSGPGKPSGL 1061
S PAP P+A G P P PA A L T+ + S P L
Sbjct: 672 SRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 722
Score = 138 bits (347), Expect = 5e-32
Identities = 216/842 (25%), Positives = 299/842 (35%), Gaps = 135/842 (16%)
Query: 269 PSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVA 328
P PVT A+ V AG V +K L+ GG G A+ P P P A
Sbjct: 35 PPPPVTPAALRVLG-AAGAVGRKPLAERA----------GGIGGATIPESAPRAGPTRSA 83
Query: 329 PGLGSSPLV-PAPNVILHRTPTPIQPKPAGVLPPKLYQLT--PKPFAPAGATLTIQGEPG 385
+P P + R P P V P T P P G ++ + E
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE-ETV 142
Query: 386 ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQP-PGALS 444
A + +AP+ A + + G P+PA+ ++ A T P+P P A
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA----RRSRAAGTEVGLPRPAPSARP 198
Query: 445 KPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPH 504
+P + +G P + + +PA A P
Sbjct: 199 RPPT-----EG-----PRKSVSSASEHSTTEPSPA-------------------ARRRPS 229
Query: 505 TGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAG 564
GG L + + A PLS +P SA AP QP +
Sbjct: 230 AGGGLQRPASRSLSSSATPLS-----SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 565 SLPTQSQPAPA-GPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE---AAPVLT 620
P + APA GP +++ L T PSA P L PATP +++ A P+
Sbjct: 285 VTPPRKDAAPALGPLSSSPL--ATPSPSAALQSQAPPTL--PATPHSSSLTCQLATPLPL 340
Query: 621 VQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVL 679
P+P APP++ T L P A P QA T + QAT PSP L+ +
Sbjct: 341 APPSPSAPPSLQT-----LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-----LA 390
Query: 680 GQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV 739
PP A P L P PL+ P +V + P + P+P
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 740 AKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
P S P+ AP AA PL+ P PS P P+ SP T P
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPM-------SPSATPP 498
Query: 800 PSRPP---SRPQSVSRPPSE-------PPLHPCPPPQA-----PPTLPGIFVIQNQLGVP 844
P PP + P +++PP + PPL P P A P P + + L P
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 845 PPASNP---APTAPGPPQPPLRPQSQPPEGP-----------------LPPAPHLPPSST 884
PP + P AP PP PP P Q P P L P P PPS +
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 885 SSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH--KSPTPPPTLHLV---PEPAAPPPPP 939
S+ S + + + T + +L+ S GP + +PPP L P + P P
Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAAWSRGPAP 677
Query: 940 PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASV 999
P F+ P LP P A G+ + G +A +L P SP S
Sbjct: 678 PLAFR--GAPGAPLPWPPA---TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS- 731
Query: 1000 LVSGQAPSGTPT-APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKP 1058
G+A +G A S +P A + L L + + S L A+ A+ G G
Sbjct: 732 --GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 789
Query: 1059 SG 1060
G
Sbjct: 790 PG 791
Score = 90.1 bits (222), Expect = 1e-17
Identities = 211/839 (25%), Positives = 280/839 (33%), Gaps = 185/839 (22%)
Query: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG-PGPSSSPSLPHQAPLGDSPHLP 792
A TP A+ GL P P P P PAA + G G L +A +P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRP-PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 793 SPHPTRPPSRP--PSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
P P+R S SRPP+ PP A T PG V P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP--AKNTSPG--------PVSSPGRAS 121
Query: 851 APTAPGP-PQPPLRPQSQP--PEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDF 906
T PGP Q LR ++ G AP SA+++ + + P P TPS
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAP------KRSALSAGARRDTSGPTPGTPSPA 175
Query: 907 QLQFPPSQGPHKS-PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
+ + G P P P+ P P P ++ + P P A +
Sbjct: 176 MARRSRAAGTEVGLPRPAPS----ARPRPPTEGPRKSVSSASEHSTTEPSPAA-----RR 226
Query: 966 VPSGIILQNKAGGA---PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPM 1022
PS AGG PA+ S+S PL+SPA SG + GTP AP+H P P
Sbjct: 227 RPS-------AGGGLQRPASRSLSSSATPLSSPAR----SGPSARGTPRAPAHPSQPKPK 275
Query: 1023 AATGL-PPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
L PP + K A L L+ + A+ P + LQ ++ PPTL +
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--AALQSQA-------PPTLPATPH 326
Query: 1082 ACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVS 1141
+ L L P +A PS + LPSP + ++
Sbjct: 327 SSSLT-CQLATPLPLAPPSPSAPPSLQ--------------TLPSP-PATPPSQATTSLG 370
Query: 1142 TQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEY 1201
+ L+ T + L L L +P A LAL A P
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPA----------------LALPPLQAPPSPPAS 414
Query: 1202 VSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTW 1261
S P+A S L+ A PPP P + A SP
Sbjct: 415 PPLS-----PLATPSP----QAPNALAVHLLQAPFSPPPSPPVQ-------APFSPP--- 455
Query: 1262 ARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKV 1321
AS +S S++ S A PS PP L++ S
Sbjct: 456 --ASPPVSPSATPPSQAP----------PSLAAPP-------------LQVPPSPPASPP 490
Query: 1322 VHNTALDPVHQPPPPPA-TLKVAEPPPRPPPP---------PPPTGQMNGTVDHPPPAAP 1371
+ +A P PPP A L++A+PPP+ PP P P G P A+
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 1372 ERKPLGT----APHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSG 1427
PL T AP PL + P +P +P +A P P P D + SG
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQV-------PPSPPASPTLQAPRRPPTPGP---DTSVSG 600
Query: 1428 LIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW-----EAPGLPPAKRRKSESPDV 1482
LA + GPPP P+ S + PD A P R P+
Sbjct: 601 PRLTLA---------LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
Query: 1483 DQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP 1541
A+ SP D A A R PAP + G P PP P
Sbjct: 652 GAAA----SPPPDAELAACHPA---------AWSRGPAPPLAFRGAPGAPLPWPPATGP 697
Score = 82.4 bits (202), Expect = 3e-15
Identities = 196/816 (24%), Positives = 263/816 (32%), Gaps = 112/816 (13%)
Query: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
+A P L P PPP PA + +G + +A IP +AP
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 770 GP----GPSSSPSLPHQAPLGDSPHLPSPHPTRP-PSRPPSRPQSVSRP----------P 814
GP G SS G P T P P P R +RP
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 815 SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP----- 869
+E + +AP ++ L PT PG P P + +S+
Sbjct: 138 AEETVARGKATEAPK--------RSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVG 188
Query: 870 -EGPLPPA-PHLPPSSTSSAVASSSETSSRLPAPT-----PSDFQLQFPPSQGPHKSPTP 922
P P A P P +V+S+SE S+ P+P + LQ P S+ S TP
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 923 -------PPTLHLVPE-PAAPPPPPPRTFQMVTTPFPALPQ--------PKALLERFHQV 966
P+ P PA P P P+ Q + P P+ P +
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 967 PSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATG 1026
PS + PA P +S+ L +P S AP T PS P A T
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 1027 L-PPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFL 1085
L P L A + S LP+ ++ A+ P P L L L+ PP+ S
Sbjct: 369 LGSPTLQATH----SFLPSPPLSPLATPPPQAPPAL----ALPPLQAPPSPPASPP---- 416
Query: 1086 EHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLL 1145
L P T P +A L H+ Q SP V F ++ +
Sbjct: 417 ----------LSP-LATPSPQAPNA----LAVHLLQAPF-SPPPSPPVQAPFSPPASPPV 460
Query: 1146 KRTQAMLNKYRLLLLEESRRVSP----SAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEY 1201
+ ++ L +V P S M Q A QLAK P
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP--- 517
Query: 1202 VSSSRSLGLP--IAASSEGHRLPGHGPLSSSA-----PGASTQP--PPHLPTKLVIRHGG 1252
+ +L P A S PG P S SA P A+ P PP L L+
Sbjct: 518 -QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 1253 AGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKI 1312
SP++ R + +S S +L A GP P +R P T G
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTL-ALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635
Query: 1313 KQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE 1372
+ + PPP A L P P PP G P P P
Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPLPWPPA 694
Query: 1373 RKPLGTAPHC----PRLPLRKTYRENVGGPGAPEGTPAGRARGG------SPAPLPAKVD 1422
P C P T PG GT G+A G S +P A++
Sbjct: 695 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 754
Query: 1423 EATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQG 1458
E G ++ A+V L R L E AA + G
Sbjct: 755 ELPLGALQ--ASVVQHLLSRTLLLAAAEGAAGGSGG 788
Score = 56.2 bits (134), Expect = 2e-07
Identities = 99/381 (25%), Positives = 133/381 (34%), Gaps = 108/381 (28%)
Query: 1203 SSSRSLGLPIAASSEGHRLPGHGP---LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSV 1259
++ +GLP A S R P GP +SS++ ++T+P P R AGG
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRPSAGGG--- 233
Query: 1260 TWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLS 1319
AS SLSSS++ S+ P+R+ P +
Sbjct: 234 LQRPASRSLSSSATPLSS------------PARSGPSAR--------------------- 260
Query: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPP-----------------PPPPTGQMNGT 1362
T P H P P L+ PP PP P P+ +
Sbjct: 261 ----GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316
Query: 1363 VDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVD 1422
PA P L T LPL P +P P+ + PA P+
Sbjct: 317 APPTLPATPHSSSL-TCQLATPLPL---------APPSPSAPPSLQTLPSPPATPPS--- 363
Query: 1423 EATSGLIRELAAVEDELYQRMLKGPPPEPAAS----AAQGTGDPDWEAPGLPPAKRRKSE 1478
+AT+ L + + L PP P A+ A P +AP PPA
Sbjct: 364 QATT----SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA------ 413
Query: 1479 SPDVDQASFSSDSPQ-DDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
SP + + ++ SPQ + L H L QAP +P PS P A PASPP
Sbjct: 414 SPPL--SPLATPSPQAPNALAVH----------LLQAP-FSPPPSPPVQAPFSPPASPPV 460
Query: 1538 LHRPEAYPPSSHNGGLGARTL 1558
P A PPS L A L
Sbjct: 461 --SPSATPPSQAPPSLAAPPL 479
Score = 51.6 bits (122), Expect = 6e-06
Identities = 98/394 (24%), Positives = 127/394 (32%), Gaps = 80/394 (20%)
Query: 1213 AASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVI--------------RHGGAGGSPS 1258
AA + R PG L+ PG+ PPP P L + R GG GG+
Sbjct: 13 AARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 1259 VTWA-RASSSLSSSSSSSSAASSLDADEDGPM--PSRNRPP------------------- 1296
A RA + S+ +SS + AS A G P++N P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 1297 -----IKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPP----- 1346
I E +R G + + + LS P P P +
Sbjct: 131 QKGLRISAEETVAR-GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 1347 PRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPA 1406
PRP P P PP P + + H P R G G PA
Sbjct: 190 PRPAPSARP---------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR--PA 238
Query: 1407 GRARGGSPAPL--PAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW 1464
R+ S PL PA+ + G R A + + PP+
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA------ 292
Query: 1465 EAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYP 1524
AP L P +P A+ S +P T H S L Q A TP P P
Sbjct: 293 -APALGPLSSSPLATPS-PSAALQSQAPPTLPATPHSSS-----LTCQLA---TPLPLAP 342
Query: 1525 HAASAGTPASPPPLHRPEAYPPSSHNGGLGARTL 1558
+ SA P S L P A PPS LG+ TL
Sbjct: 343 PSPSA--PPSLQTLPSPPATPPSQATTSLGSPTL 374
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 136 bits (342), Expect = 2e-31
Identities = 229/835 (27%), Positives = 302/835 (36%), Gaps = 163/835 (19%)
Query: 309 GAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTP 368
G ++ PT P Q L + + +SP P P + R P P+ P L Q+ P
Sbjct: 1029 GPELSAQPTPGPVPQVLPASLMVSASPAGP-PLIPASRPPGPVLLPPLQPNSGSLPQVLP 1087
Query: 369 KPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLS------GFPAPALQAN 422
P T +L P AP L+ A G + +L G+ P A
Sbjct: 1088 SPLGVLSGTSRPPTPTLSLKPTPPAPVRLS--PAPPPGSSSLLKPLTVPPGYTFPPAAAT 1145
Query: 423 VFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQL 482
AT T A P P A P + +L Q LP V +
Sbjct: 1146 TTSTTTATATTTAVPAPTPA------------------PQRLILSPDMQARLPSGEVVSI 1187
Query: 483 PQQLSALP---ANVGG------QILAAAAPHTGGQL----IANPILTNQNLAGPLSLGPV 529
Q S AN GG QI TG Q+ + P +N+ +S G
Sbjct: 1188 GQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGG- 1246
Query: 530 LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP 589
H + AH+ A IQ P PVS+ S P+ + PAP G + L +P
Sbjct: 1247 -QHHLISQPAHV---ALIQAVAPTPGPTPVSVLPSSTPSTT-PAPTG--LSLPLAANQVP 1299
Query: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649
P+ V NT G+V+ A PV + PAP+ P S+ LP L P +
Sbjct: 1300 PTMVN--NT--GVVKIVVRQAPRDGLTPVPPLAPAPRPP---SSGLPAVLNPRPTLTPGR 1352
Query: 650 APTPQ---AAAP-PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS 705
PTP A AP P T +P L SP V P A P I + + LP S
Sbjct: 1353 LPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPAS 1412
Query: 706 Q-QPLSAEGPHLSVPASVIVSAP--------PPAQDPAPAT-----PVAKGAGLGPQAPD 751
P+ P L+ P S VS P P PAPA+ P++ + P
Sbjct: 1413 SPMPIPNSSP-LASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471
Query: 752 SQASPAP--APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS------PHPTRPPSRP 803
S P AP +PAA PGP P AP G SP + P+ S+
Sbjct: 1472 LLTSVTPPLAPVVPAA-----PGP------PSLAPSGASPSASALTLGLATAPSLSSSQT 1520
Query: 804 PSRPQSVSRPPSEPP-LHPCPPPQAPPTLPGIFVIQNQLGVP-PPASNPAPTAPGPPQP- 860
P P ++ S P L+ P P L V + L P P A NPAP P
Sbjct: 1521 PGHPLLLAPTSSHVPGLNSTVAPACSPVL----VPASALASPFPSAPNPAPAQASLLAPA 1576
Query: 861 ---------PLRPQSQP--------PEGPLPPAPHLPPSSTSSAVASSSET--------- 894
PL P + P P PL P P L PS ++ V +SS+T
Sbjct: 1577 SSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS 1636
Query: 895 --------SSRLPAPTP----SDFQLQFP-PSQGPHKSPTPPPTLHLVPE--PAAPPPPP 939
+S +PAPTP S Q P P P SP TL L P P P
Sbjct: 1637 TPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSP 1696
Query: 940 PRTFQMVTT----PFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP 995
+T + T PFP Q +L VP+ + A G P P + SL P
Sbjct: 1697 SQTLSLGTGNPQGPFPT--QTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAP---- 1750
Query: 996 AASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
AP P AP+ PAP L P + + +++ TL ++ A
Sbjct: 1751 ---------AP---PLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPA 1793
Score = 131 bits (329), Expect = 6e-30
Identities = 249/919 (27%), Positives = 348/919 (37%), Gaps = 158/919 (17%)
Query: 127 GPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQD 186
GP LP LQP G PQ L L G PPT PP
Sbjct: 1068 GPVLLPPLQPNSGSL--------------PQVLPSPLGVLSGTSRPPTPTLSLKPTPPAP 1113
Query: 187 VVNKALSVQPFLQPVGLGNVTLQPI---PGLQGLPNG----SPGGATAATLGL-----AP 234
V LS P P G ++ L+P+ PG P S ATA T + AP
Sbjct: 1114 V---RLSPAP---PPGSSSL-LKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAP 1166
Query: 235 IQVVGQPVMALNTPTSQLLAKQVPVSGYLASAA-------GPSEPVTLASAGVSPQGAGL 287
+++ P M P+ ++++ G LAS A G S+P+T G G
Sbjct: 1167 QRLILSPDMQARLPSGEVVS-----IGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGA 1221
Query: 288 VIQKNLSAAVATTLNGNSV-FGGAGAASAPTGTPSGQPL--AVAPGLGSSPLVPAPNVIL 344
+++ L+ L N V AG P+ L AVAP G +P+ P+
Sbjct: 1222 QVRQ-LAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTP 1280
Query: 345 HRTPTPIQ---PKPAGVLPPKLYQ----------------LTP-KPFAPAGATLTIQGEP 384
TP P P A +PP + LTP P APA + G P
Sbjct: 1281 STTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPS-SGLP 1339
Query: 385 GALPQQPK-APQNLTFMAAGKAGQNVVLSGFPAPALQANVFK---QPPATTTGAAPPQPP 440
L +P P L G A + P P L + K P + +AP P
Sbjct: 1340 AVLNPRPTLTPGRLPTPTLGTAR-----APMPTPTLVRPLLKLVHSPSPEVSASAPGAAP 1394
Query: 441 GALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLL--PGAPAVQLPQQLSALPANVGGQIL 498
+S P+ V SS+ PA +P N L P + V +P S+LP +V +
Sbjct: 1395 LTISSPLHVP-----SSLPGPASSPMPIPNSSPLASPVSSTVSVPLS-SSLPISVPTTLP 1448
Query: 499 A-AAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
A A+AP T I+ P+ + + GP L V P A ++ AAP G P+L
Sbjct: 1449 APASAPLTIP--ISAPLTVSAS--GPALLTSVTPP-----LAPVVPAAP---GPPSLAPS 1496
Query: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSA--VAMLNT-----------PDGLVQ 604
S +A +L AP+ ++ T + L P++ V LN+ P +
Sbjct: 1497 GASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALA 1556
Query: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPL-PLGLQQPQAQQPPQAPTPQAAAPPQATT 663
P+A A + PA A A++TPL P+ Q P AP P A P A +
Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP-PLAPLPVLAPS 1615
Query: 664 PQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVI 723
P +P LASS + + PS+TP L S P+ A P L+ P+S
Sbjct: 1616 PGAAPVLASSQTPVPV-MAPSSTPGTSLA------------SASPVPAPTPVLA-PSSTQ 1661
Query: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIP-AAAPLKGPGPSSSPSLPHQ 782
P P P P+ + L P + +P+ + +GP P+ + SL
Sbjct: 1662 TMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPA 1721
Query: 783 APLGDSPHLPSPHPT--RPPSRPPSRPQSVSRPPSEPPLHPCPP-PQAPPTLPGIFVIQN 839
+ L +P+P T P P Q++S P+ PPL P P AP + +
Sbjct: 1722 SSL-----VPTPAQTLSLAPGPPLGPTQTLSLAPA-PPLAPASPVGPAPAHTLTLAPASS 1775
Query: 840 QLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS---- 895
+ PAS T P P L P + P + P S SS V S+S +
Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPV 1835
Query: 896 ---SRLPA--PTPSDFQLQFPPSQGPHKSPTPPPTLHLV--PEPAAPPPPPPRT-FQMVT 947
SRLP P L+ P P+PP T P P PPPPPR+ F + +
Sbjct: 1836 TMVSRLPVSKDEPDTLTLRSGP-------PSPPSTATSFGGPRPRRQPPPPPRSPFYLDS 1888
Query: 948 TPFPALPQPKALLERFHQV 966
Q LER Q+
Sbjct: 1889 LEEKRKRQRSERLERIFQL 1907
Score = 127 bits (320), Expect = 6e-29
Identities = 264/1008 (26%), Positives = 352/1008 (34%), Gaps = 195/1008 (19%)
Query: 157 QALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKAL-------SVQPFLQPVGLG-NVTL 208
Q + G DL+GL+G + +P + + L P +PV + N L
Sbjct: 939 QRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRML 998
Query: 209 QPIPGLQG---LPNGSPGGATAATLGLAPIQVVGQPVMALNT---PTSQLLAKQVPVSGY 262
QP+P +G + +P A LG P++ P ++ P Q+L + VS
Sbjct: 999 QPVPKQEGRTVVVVNNP----RAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVS-- 1052
Query: 263 LASAAGPSEPVTLASAGVSPQGAGLV--IQKNLSAAVATTLNGNSVFGGAGAASAPTGTP 320
AS AGP P+ AS P G L+ +Q N S ++ L +P G
Sbjct: 1053 -ASPAGP--PLIPASR---PPGPVLLPPLQPN-SGSLPQVL------------PSPLGVL 1093
Query: 321 SGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP---FAPAGAT 377
SG P L P PAP + +P P P + +L P LT P F PA AT
Sbjct: 1094 SGTSRPPTPTLSLKPTPPAP---VRLSPAP-PPGSSSLLKP----LTVPPGYTFPPAAAT 1145
Query: 378 LT----IQGEPGALPQQPKAPQNLTF---MAAGKAGQNVVLSGFPAPALQ---ANVFKQP 427
T A+P APQ L M A VV G A Q AN
Sbjct: 1146 TTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSK 1205
Query: 428 PAT---------TTGAAPPQPPGALSKPMS---VHLLNQGSSIVIPAQHMLPGQNQFLLP 475
P T TGA Q +P+ VHL++ G QH L Q
Sbjct: 1206 PLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGG------QHHLISQ------ 1253
Query: 476 GAPA-VQLPQQLSALPANVGGQILAAAAPHT--GGQLIANPILTNQ------NLAGPLSL 526
PA V L Q ++ P +L ++ P T ++ P+ NQ N G + +
Sbjct: 1254 --PAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKI 1311
Query: 527 GPVLAPHSGAHSAHILSAAPI--QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQ 584
AP G L+ AP G PA+ +L G LPT + P T L
Sbjct: 1312 VVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV 1371
Query: 585 GVTL------------------PPSAVAMLNTPDGLVQPATPAAATGEAAP--------- 617
L P + + L+ P L PA+ ++P
Sbjct: 1372 RPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV 1431
Query: 618 -----------VLTVQPAPQAPPA---VSTPLPLGLQQPQ---AQQPPQAPTPQAAAPPQ 660
V T PAP + P +S PL + P + PP AP AA P
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491
Query: 661 ATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL-SAEGPHLS-- 717
+ P G + S + LG + + ++ T + P L S P S
Sbjct: 1492 SLAPS---GASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548
Query: 718 -VPASVIVSAPPPAQDPAPA----------TPVAKGAGLGPQAPDSQASPAPAPQIPAAA 766
VPAS + S P A +PAPA A L P A A AP+P P A
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAP 1608
Query: 767 -PLKGPGPSSSPSL-------PHQAPL---GDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815
P+ P P ++P L P AP G S SP P P PS Q++ P
Sbjct: 1609 LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPV 1668
Query: 816 EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ--SQPPEGPL 873
PL P P + TL + LG P S G PQ P Q S P L
Sbjct: 1669 PSPL---PSPASTQTLALAPALAPTLGGSSP-SQTLSLGTGNPQGPFPTQTLSLTPASSL 1724
Query: 874 PPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPA 933
P P S ++T S PAP P + P P TL L P +
Sbjct: 1725 VPTPAQTLSLAPGPPLGPTQTLSLAPAP---------PLAPASPVGPAPAHTLTLAPASS 1775
Query: 934 APPPPPPRTFQMVT-------TPFPALPQPKALLERFHQVPSGII--LQNKAGGAPAAPQ 984
+ P + Q +T T PA Q AL Q P+ L A GA P
Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPV 1835
Query: 985 TSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLP 1032
T S P++ L P P+ + P P PP P
Sbjct: 1836 TMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSP 1883
Score = 101 bits (251), Expect = 6e-21
Identities = 230/933 (24%), Positives = 324/933 (34%), Gaps = 172/933 (18%)
Query: 513 PILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPA--LFQMPVSLAAGSLPTQS 570
P L+ Q GP+ P + P S SA I +P + P+ +GSLP Q
Sbjct: 1030 PELSAQPTPGPV---PQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLP-QV 1085
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLN-TPDGLVQ--PATPAAATGEAAPVLTVQPAPQA 627
P+P G VL G + PP+ L TP V+ PA P ++ P LTV P
Sbjct: 1086 LPSPLG-----VLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKP-LTVPPGYTF 1139
Query: 628 PPAVSTPLPLGLQQPQAQQPPQAPTP---QAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
PPA +T P APTP + P PS + S + L Q P
Sbjct: 1140 PPAAATTTSTTTATATTTAVP-APTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPV 1198
Query: 685 AT-----PTAILTQDSL---------QMFLPQERSQQP-----LSAEGPH--LSVPASV- 722
A P Q + Q+ + Q R Q +SA G H +S PA V
Sbjct: 1199 ANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVA 1258
Query: 723 IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAA--------------APL 768
++ A P P P + + AP + P A Q+P AP
Sbjct: 1259 LIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPR 1318
Query: 769 KGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP--------LH 820
G P + + P P + +P PT P R P+ +R P P L
Sbjct: 1319 DGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLV 1378
Query: 821 PCPPPQAPPTLPGI--FVIQNQLGVPPPASNPAPTAPGPPQPPLR-PQSQPPEGPLPPAP 877
P P+ + PG I + L VP + PGP P+ P S P P+
Sbjct: 1379 HSPSPEVSASAPGAAPLTISSPLHVPS-------SLPGPASSPMPIPNSSPLASPVSSTV 1431
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP---PSQGPHK-SPTPPPTLHLVPEPA 933
+P SS++ S T+ PA P + P + GP + PP +VP
Sbjct: 1432 SVP---LSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488
Query: 934 APPPPPPR---------TFQMVTTPFPALPQ----PKALLERFHQVP----------SGI 970
PP P T + T P + Q P L VP S +
Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548
Query: 971 ILQNKAGGAP--AAPQTSTSLGPLTSPAASV---LVSGQAPSGTPTAPSHAPAPAPMAAT 1025
++ A +P +AP + + L +PA+S L + AP P AP+PAP A
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAP 1608
Query: 1026 GLPPLLPAENKA--FASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEAC 1083
LP L P+ A AS+ + V A SS PG + L S + P L PS
Sbjct: 1609 -LPVLAPSPGAAPVLASSQTPVPV-MAPSSTPG--TSLASASPVPA--PTPVLAPSSTQT 1662
Query: 1084 FL-EHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVST 1142
L + S P+ L P +P F T +
Sbjct: 1663 MLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQG------PFPTQTL 1716
Query: 1143 QLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYV 1202
L + + + L L + P+ + +LA LA P V
Sbjct: 1717 SLTPASSLVPTPAQTLSLAPGPPLGPT-------------QTLSLAPAPPLAPASP---V 1760
Query: 1203 SSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWA 1262
+ + L +A +S L L+ ++ T P +PT G + + T A
Sbjct: 1761 GPAPAHTLTLAPASSSASL-----LAPASVQTLTLSPAPVPT--------LGPAAAQTLA 1807
Query: 1263 RASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVV 1322
A +S+ S +S ASSL G P L + + +SK
Sbjct: 1808 LAP---ASTQSPASQASSLVVSASGAAP-----------------LPVTMVSRLPVSKDE 1847
Query: 1323 HNTALDPVHQPPPPPATLKVAEPPPRPPPPPPP 1355
+T P PP P PR PPPPP
Sbjct: 1848 PDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPP 1880
Score = 98.2 bits (243), Expect = 5e-20
Identities = 241/1067 (22%), Positives = 375/1067 (35%), Gaps = 186/1067 (17%)
Query: 541 ILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD 600
+L P Q G+ + G +P + P P A T + P+++ + +P
Sbjct: 997 MLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPA 1056
Query: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQA----PTPQAA 656
G P PA+ + +QP + P V P PLG+ ++ P PTP A
Sbjct: 1057 G--PPLIPASRPPGPVLLPPLQPNSGSLPQV-LPSPLGVLSGTSRPPTPTLSLKPTPPA- 1112
Query: 657 APPQATTPQPSPGLASSPEKIVLGQ----PPSA---TPTAILTQDSLQMFLPQERSQQPL 709
P +P P PG +S + + + PP+A T T T + + P Q+ +
Sbjct: 1113 --PVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLI 1170
Query: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
+ +P+ +VS A PVA G P Q +
Sbjct: 1171 LSPDMQARLPSGEVVSIGQLAS--LAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAV 1228
Query: 770 GPGPSSSPSLPHQAPLGDSPHL--------------PSPHPTRPPSRPPSRPQSVSRPPS 815
G ++ H G HL P+P PT P S PS S + P+
Sbjct: 1229 GQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPT-PVSVLPSSTPSTTPAPT 1287
Query: 816 EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875
L P Q PPT+ N GV AP P PPL P +PP LP
Sbjct: 1288 GLSL-PLAANQVPPTMV------NNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPA 1340
Query: 876 APHLPPSSTSSAVASSSETSSRLPAPTPSDFQ--LQFPPSQGPHKSPTPP--------PT 925
+ P+ T + + + ++R P PTP+ + L+ S P S + P
Sbjct: 1341 VLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSP 1400
Query: 926 LHL---VPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAA 982
LH+ +P PA+ P P P + + + + P + +P I + +A
Sbjct: 1401 LHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLS-----SSLP--ISVPTTLPAPASA 1453
Query: 983 PQTSTSLGPLT-SPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASN 1041
P T PLT S + L++ P P P+ AP P +A +G P A A+
Sbjct: 1454 PLTIPISAPLTVSASGPALLTSVTPPLAPVVPA-APGPPSLAPSGASPSASALTLGLAT- 1511
Query: 1042 LPTLNVAKAASSGPGKPSGL-QYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDY 1100
P+L ++S PG P L S + GL T+ P AC VL P
Sbjct: 1512 APSL----SSSQTPGHPLLLAPTSSHVPGLNS--TVAP---AC---------SPVLVPAS 1553
Query: 1101 KTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLL 1160
A P F A + P+P+ ++ +QA+ +
Sbjct: 1554 ALASP-FPSAPN------------PAPAQ--------ASLLAPASSASQALATPLAPMAA 1592
Query: 1161 EESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHR 1220
++ ++PS + + A + + P ++ S + G +A++S
Sbjct: 1593 PQTAILAPSPAPPLAPLPVLAPSPG--AAPVLASSQTPVPVMAPSSTPGTSLASAS---- 1646
Query: 1221 LPGHGPLSSSAPGAS-TQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAAS 1279
P P AP ++ T P +P+ L + ++ A A + SS S S
Sbjct: 1647 -PVPAPTPVLAPSSTQTMLPAPVPSPL----PSPASTQTLALAPALAPTLGGSSPSQTLS 1701
Query: 1280 SLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPAT 1339
+ GP P++ L + + L T P P T
Sbjct: 1702 LGTGNPQGPFPTQT----------------LSLTPASSLVPTPAQTLSLAPGPPLGPTQT 1745
Query: 1340 LKVAEPPPRPP-----PPPPPT---GQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTY 1391
L +A PP P P P T + + PA+ + L AP P L
Sbjct: 1746 LSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAP-VPTL------ 1798
Query: 1392 RENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSG-------LIRELAAVEDELYQRML 1444
GP A + A SPA + + + SG ++ L +DE L
Sbjct: 1799 -----GPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTL 1853
Query: 1445 KGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSA 1504
+ PP P ++A G P RR + P ++ F DS ++ +
Sbjct: 1854 RSGPPSPPSTATSFGG----------PRPRR--QPPPPPRSPFYLDSLEEKRKRQR-SER 1900
Query: 1505 IDSILNLQQAPGRTPAPSY------------PHAASAGTPASPPPLH 1539
++ I L +A G AP Y P A+ G P SP P H
Sbjct: 1901 LERIFQLSEAHGAL-APVYGTEVLDFCTLPQPVASPIG-PRSPGPSH 1945
Score = 74.7 bits (182), Expect = 6e-13
Identities = 160/677 (23%), Positives = 231/677 (34%), Gaps = 178/677 (26%)
Query: 326 AVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPG 385
A G +P++ A TP P V P + P P + A + P
Sbjct: 2404 AETQGANHTPVISAHQTRSTTTPPRCSPARERV-PRPAPRPRPTPASAPAAIPALVPVPV 2462
Query: 386 ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQ---PPGA 442
+ P AP +T + +L P P+ + PP ++ PP PP A
Sbjct: 2463 SAPVPISAPNPITILPVH------ILPSPPPPS------QIPPCSSPACTPPPACTPPPA 2510
Query: 443 LSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQI-LAAA 501
+ P PAQ L + LL G P+V + ++ LP + + L A
Sbjct: 2511 HTPP--------------PAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQ 2556
Query: 502 APHTGGQL----IANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
A + L +A+ ++ +L P L PV A S LS P P+L
Sbjct: 2557 ALASPESLELASVASSETSSLSLVPPKDLLPV-AVEILPVSEKNLSLTP---SAPSL--- 2609
Query: 558 PVSLAAGSLPT-QSQPAPAGPAATTVL---------------QGVTLPPSAVA------- 594
+L AGS+P Q Q AP TT+ G+ LPPSA +
Sbjct: 2610 --TLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEP 2667
Query: 595 --MLNTPDGLVQPATPAAATGEAAPVLTVQ----------------PAPQAPPAVSTPLP 636
T + L + TP ++ + ++T + P+P PP T
Sbjct: 2668 LEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSAD 2727
Query: 637 LGLQQPQAQQPPQAPTPQ----------------------------------AAAPPQAT 662
+ ++ +P Q P P+ + A+
Sbjct: 2728 VEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSAS 2787
Query: 663 TPQPSPGLASSPEKI-VLGQPPSATPTAILTQDSLQMFLPQERSQ-------QPLSAEGP 714
PS S PE +G P A P++ L Q F+ + + P + +G
Sbjct: 2788 PGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGA 2847
Query: 715 HLSV--PASVIVSAPPPAQDPAPATPVAKGAGLG-PQAPDSQ-------ASPAPAPQIPA 764
L++ PA PP ++ +PA AG G +AP S A P P P+
Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPA-----DAGRGVDEAPSSTLKGKTNGADPVPGPETLI 2902
Query: 765 AAPLKGPGPSSSPSL-PHQAPLGDSP-HLP----SPHPTRPPSRPP------------SR 806
A P P L P PLG P H P SP R RPP S
Sbjct: 2903 VA-----DPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSA 2957
Query: 807 PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA--SNPAPTAPGPPQPPLRP 864
S ++PP HP P PP L V P A +N T PP R
Sbjct: 2958 GDGNSESRTQPPPHPSPLTPLPPLL-----------VCPTATVANTVTTVTISTSPPKRK 3006
Query: 865 QSQPPEGPLPPAPHLPP 881
+ +PP+ P P P P
Sbjct: 3007 RGRPPKNPPSPRPSQLP 3023
Score = 70.1 bits (170), Expect = 2e-11
Identities = 179/761 (23%), Positives = 246/761 (32%), Gaps = 136/761 (17%)
Query: 802 RPPSRPQSVSRPPSEPPLHPCPPP-QAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP 860
R P P V RPP P L P P P LP ++ PA P A PP P
Sbjct: 1016 RAPLGPVPV-RPPPGPELSAQPTPGPVPQVLPASLMVSAS-----PAGPPLIPASRPPGP 1069
Query: 861 PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP 920
L P QP G LP P S +SR P PT S P
Sbjct: 1070 VLLPPLQPNSGSLPQVLPSPLGVLSG--------TSRPPTPTLS-------------LKP 1108
Query: 921 TPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAP 980
TPP + L P APPP + +T P P P A
Sbjct: 1109 TPPAPVRLSP---APPPGSSSLLKPLTVP-PGYTFPPA---------------------- 1142
Query: 981 AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL---LPAENKA 1037
AA TST+ T+ A AP PAP P + LP+
Sbjct: 1143 AATTTSTTTATATTTAVP-----------------APTPAPQRLILSPDMQARLPSGEVV 1185
Query: 1038 FASNLPTLNVAKAASSGPGKPSGLQYESK---LSG--LKKPPTLQPSKEACFLEHLHKHQ 1092
L +L A++G KP Q + L+G +++ QP + HL
Sbjct: 1186 SIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAG 1245
Query: 1093 GSVLHPDYKTAFPSFEDALHRLL--PYHV--YQGALPSPSDYHKVDEEFETVSTQLLKRT 1148
G H L+ P HV Q P+P T ST T
Sbjct: 1246 GQ-----------------HHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPST-----T 1283
Query: 1149 QAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSL 1208
A L L + +V P+ M++ + + A L P S
Sbjct: 1284 PAPTG---LSLPLAANQVPPT----MVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSS 1336
Query: 1209 GLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLV-IRHGGAGGSPSVTWARASSS 1267
GLP + PG P + + P P L L+ + H SP V+ + ++
Sbjct: 1337 GLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSP---SPEVSASAPGAA 1393
Query: 1268 LSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTAL 1327
+ SS SSL PMP N P+ + S + + L + + A
Sbjct: 1394 PLTISSPLHVPSSLPGPASSPMPIPNSSPLAS-PVSSTVSVPLSSSLPISVPTTLPAPAS 1452
Query: 1328 DPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPL 1387
P+ P P T+ + P PP V P P P G +P L L
Sbjct: 1453 APLTIPISAPLTVSASGPALLTSVTPP-----LAPVVPAAPGPPSLAPSGASPSASALTL 1507
Query: 1388 RKTYRENVGGPGAPEGTPAGRARGGSPAP-LPAKVDEATSGLIRELAAVEDELYQRMLKG 1446
++ P G P A S P L + V A S ++ +A+
Sbjct: 1508 GLATAPSLSSSQTP-GHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPA 1566
Query: 1447 PPP----EPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQ 1502
P PA+SA+Q P A S +P + + SP + Q
Sbjct: 1567 PAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQ 1626
Query: 1503 SAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEA 1543
+ + + AP TP S ASA +P P+ P +
Sbjct: 1627 TPVPVM-----APSSTPGTS---LASASPVPAPTPVLAPSS 1659
Score = 69.3 bits (168), Expect = 3e-11
Identities = 151/634 (23%), Positives = 211/634 (33%), Gaps = 114/634 (17%)
Query: 532 PHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS 591
P + A I + P+ V P P + LP P+P P+ +PP
Sbjct: 2445 PTPASAPAAIPALVPVPVSAPVPISAPNPITI--LPVHILPSPPPPSQ--------IPPC 2494
Query: 592 AVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVS-----TPLPLGLQQPQAQQ 646
+ P P + V P PP+V T LPLGL+ P+A+
Sbjct: 2495 SSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLR-PEAEL 2553
Query: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706
QA A P++ + + +S + L P P A+ LP
Sbjct: 2554 -----CAQALASPESL--ELASVASSETSSLSLVPPKDLLPVAV-------EILPVSEKN 2599
Query: 707 QPLSAEGPHLSVPASVIVSAPPP-AQDPAPAT-----------PVAKGAGLGPQAPDSQA 754
L+ P L++ A I + A D A T P+ G + P S A
Sbjct: 2600 LSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAA 2659
Query: 755 SPAPAPQIPAAAP------LKGPGPSSSPSLPHQ-------APLGDSPHLPSPH---PTR 798
S P Q P A + P+SSP P + AP S SP P R
Sbjct: 2660 SDEPL-QEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPAR 2718
Query: 799 PPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFV--------IQNQLGVPPPASNP 850
PP R S + + P P P P+ LPG V ++ + AS
Sbjct: 2719 PPRRRTSADVEIRGQGTGRPGQP-PGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTL 2777
Query: 851 AP----TAPGPPQPPLR----PQSQPP-EGPLPPAPH----LPPSSTSSAVASSSETSSR 897
P T+ P P +R P+S PP GP AP PP A +
Sbjct: 2778 VPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTG 2837
Query: 898 LPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP--PPPPPRTFQMVTTPFPALPQ 955
+P D L + PP + P A P T + T +P
Sbjct: 2838 GGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPG 2897
Query: 956 PKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP-----------AASVLVSGQ 1004
P+ L+ + +I G P PQ PL SP A + + G
Sbjct: 2898 PETLIVADPVLEPQLI----PGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGT 2953
Query: 1005 APS-GTPTAPSHA-PAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQ 1062
S G + S P P P T LPPLL A+ + T+ + ++S P + G
Sbjct: 2954 ISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTI---STSPPKRKRG-- 3008
Query: 1063 YESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVL 1096
+PP PS L L + SVL
Sbjct: 3009 ---------RPPKNPPSPRPSQLPVLDRDSTSVL 3033
Score = 67.0 bits (162), Expect = 1e-10
Identities = 183/776 (23%), Positives = 268/776 (34%), Gaps = 134/776 (17%)
Query: 741 KGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH-QAPLGDSPHLP--SPHPT 797
+G G G ++ A AP + PG S L +A + H P S H T
Sbjct: 2362 EGPGAGDESSCGTGGGTHRRSKKAKAPER-PGTRVSERLRGARAETQGANHTPVISAHQT 2420
Query: 798 RPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGP 857
R + PP + R P P P AP +P + VP P S P P +
Sbjct: 2421 RSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPAL--------VPVPVSAPVPISAPN 2472
Query: 858 PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH 917
P L P PP +PP S+ PA TP PP+ P
Sbjct: 2473 PITILPVHILPSP---PPPSQIPPCSS--------------PACTP-------PPACTPP 2508
Query: 918 KSPTPPPTLHLVPEPAAP----PPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQ 973
+ TPPP + P++P PP P + + P P+ + + P + L
Sbjct: 2509 PAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALAS-PESLELA 2567
Query: 974 NKAGGAPAAPQTSTSLGP---LTSPAASVL-VSGQAPSGTPTAPSHAPAPAPMAATGLPP 1029
+ A ++ +S SL P L A +L VS + S TP+APS
Sbjct: 2568 SVA----SSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPS--------------- 2608
Query: 1030 LLPAENKAFASNLPTLNVAKAASSGPGK-----PSGLQYE---SKLSGLKKPPTLQPSKE 1081
L E A ++P +A S G P G + S+ +GL+ PP+ + +
Sbjct: 2609 -LTLE----AGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPS--AASD 2661
Query: 1082 ACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVS 1141
E L + S + KT S E L+ V A PS S E + +
Sbjct: 2662 EPLQEPLEADRTSEELTEAKTPTSSPEKP-QELVTAEV---AAPSTSSSATSSPEGPSPA 2717
Query: 1142 TQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEY 1201
+RT A + + P + R+ E+ L ++ +
Sbjct: 2718 RPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTL 2777
Query: 1202 V----SSSRSLGLPIAASSEG-HRLPGHGPLSSSAPGASTQPPPHLP--TKLVIRHGGAG 1254
V +S S G P S G P G +AP +S PP P + I G G
Sbjct: 2778 VPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTG 2837
Query: 1255 GSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQ 1314
G S + + L R RPP K RS + +
Sbjct: 2838 G---------------GSPENGDGALLAITPPAVKRRRGRPPKKN---RSPADAGRGVDE 2879
Query: 1315 EAGLSKVVHNTALDPVHQPPPPPATLKVAEP--PPRPPPPPPPTGQMNGTVDHPPPAAPE 1372
+ DPV P P TL VA+P P+ P P P G +P + E
Sbjct: 2880 APSSTLKGKTNGADPV----PGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVE 2935
Query: 1373 RKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIREL 1432
++ G P LP+ T A +G R + P P P+ + L+
Sbjct: 2936 KRRRGRPPKARDLPIPGTI------SSAGDGNSESRTQ---PPPHPSPLTPLPPLLVCPT 2986
Query: 1433 AAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFS 1488
A V + + + PP+ + G P P PP+ R S+ P +D+ S S
Sbjct: 2987 ATVANTVTTVTISTSPPK------RKRGRP----PKNPPSP-RPSQLPVLDRDSTS 3031
Score = 60.5 bits (145), Expect = 1e-08
Identities = 100/439 (22%), Positives = 142/439 (32%), Gaps = 103/439 (23%)
Query: 644 AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703
A Q TP +P + P+P+P +P P+A P + S +
Sbjct: 2417 AHQTRSTTTPPRCSPARERVPRPAPRPRPTP-----ASAPAAIPALVPVPVSAPV----- 2466
Query: 704 RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIP 763
P+SA P +P ++ S PPP+Q P ++P P PA +
Sbjct: 2467 ----PISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVT 2522
Query: 764 AAAP-LKGPGPSSSPSLPHQA-----PLGDSPH-------LPSPHPTRPPSRPPSRPQSV 810
++P L GP PS+P A PLG P L SP S S S+
Sbjct: 2523 PSSPLLLGP-----PSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSL 2577
Query: 811 SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPE 870
S P + L P A LP V + L + P A + A P + E
Sbjct: 2578 SLVPPKDLL-----PVAVEILP---VSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAE 2629
Query: 871 GP----LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP-----------PSQG 915
G LP LP + S LP SD LQ P ++
Sbjct: 2630 GTTLTVLPEGEELP-------LCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT 2682
Query: 916 PHKSPTPPPTLHLV-----------------PEPAAPP--------------------PP 938
P SP P L P PA PP PP
Sbjct: 2683 PTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPP 2742
Query: 939 PPRTFQMVTTPFPALPQPKALLERFHQ----VPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
P+ + + + + K L+ R Q + + ++ +P +P + GP +S
Sbjct: 2743 GPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESS 2802
Query: 995 PAASVLVSGQAPSGTPTAP 1013
P S PT P
Sbjct: 2803 PPIGGPCEAAPSSSLPTPP 2821
Score = 55.5 bits (132), Expect = 4e-07
Identities = 170/733 (23%), Positives = 246/733 (33%), Gaps = 159/733 (21%)
Query: 876 APHLPPSSTSSAVASS-SETSSRLPAPTPSDFQLQF---PPSQGPHKSPTPPPTLHLVPE 931
AP P + S + + +ET P S Q + PP P + P P P
Sbjct: 2387 APERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPT 2446
Query: 932 PAAPPPPPPRTFQM-VTTPFP-ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
PA+ P P + V+ P P + P P +L H +PS P + +
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILP-VHILPS--------------PPPPSQI 2491
Query: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA-ATGLPPLLPAENKAFASNLPTLNVA 1048
P +SPA + P+ TP P+H P PA T PLL P++ ++
Sbjct: 2492 PPCSSPACT-----PPPACTPP-PAHTPPPAQTCLVTPSSPLLLGP--------PSVPIS 2537
Query: 1049 KAASSGPGKPSGLQYESKL--SGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPS 1106
+ ++ P GL+ E++L L P +L+ + A S
Sbjct: 2538 ASVTN---LPLGLRPEAELCAQALASPESLELASVA-----------------------S 2571
Query: 1107 FEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRV 1166
E + L+P P D V E VS + L T + + L E+ +
Sbjct: 2572 SETSSLSLVP----------PKDLLPVAVEILPVSEKNLSLTPSAPS-----LTLEAGSI 2616
Query: 1167 SPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGP 1226
E D E TTL + + E+ VS S L LP +A+S+ P P
Sbjct: 2617 PNGQEQEAPD----SAEGTTLTVLPE--GEELPLCVSESNGLELPPSAASDE---PLQEP 2667
Query: 1227 LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADED 1286
L + PT SP ++ +++ S+SSSA SS +
Sbjct: 2668 LEADRTSEELTEAK-TPTS----------SPEKPQELVTAEVAAPSTSSSATSS----PE 2712
Query: 1287 GPMPSRNRPPIKTYEARSRI------------GLKLKIKQEAGLSKVVHNTAL-DPVHQP 1333
GP P+ RPP + A I G K+ K L VV L Q
Sbjct: 2713 GPSPA--RPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQ 2770
Query: 1334 PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP-ERKPLGTAPHCPRLPL--RKT 1390
+TL P P M+G PP P E P + P P+ P R+
Sbjct: 2771 RGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRH 2830
Query: 1391 YRENVGGPGAPEG---------TPAGRARGG-------SPAPLPAKVDEATSGLIR---- 1430
V G G+PE PA + R G SPA VDEA S ++
Sbjct: 2831 IELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTN 2890
Query: 1431 ---------ELAAVEDELYQRMLKGPP---PEPAASAAQGTGDPDWEAPGLPPAKR---- 1474
L + L +++ GP P+P + G PP R
Sbjct: 2891 GADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPI 2950
Query: 1475 --RKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTP 1532
S + D + S + P LT + + + P G P
Sbjct: 2951 PGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRP 3010
Query: 1533 ASPPPLHRPEAYP 1545
PP RP P
Sbjct: 3011 PKNPPSPRPSQLP 3023
Score = 41.6 bits (96), Expect = 0.006
Identities = 49/203 (24%), Positives = 78/203 (38%), Gaps = 25/203 (12%)
Query: 1295 PPIKTYEARSRIGLKLK-IKQEAGLSKVVHNTALDPVHQPP--PPPATLKVAEPPPRPPP 1351
PP + + ++ L+ + ++ G + VV N P+ P PPP A+P P P P
Sbjct: 983 PPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVP 1042
Query: 1352 PPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARG 1411
P M PP P +P G P P + + + +P G +G +R
Sbjct: 1043 QVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVL---PSPLGVLSGTSRP 1099
Query: 1412 GSPA-------PLPAKVDEA----TSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTG 1460
+P P P ++ A +S L++ L + PP A + + T
Sbjct: 1100 PTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTF-------PPAAATTTSTTTA 1152
Query: 1461 DPDWEA-PGLPPAKRRKSESPDV 1482
A P PA +R SPD+
Sbjct: 1153 TATTTAVPAPTPAPQRLILSPDM 1175
Score = 33.1 bits (74), Expect = 2.2
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 706 QQPLSAEGPHLSVPASVIVS----APPPAQDPAPATPVAKGAG-LGPQ--APDSQASPAP 758
Q S P L V + +VS P + ++P + GAG + PQ A DS P
Sbjct: 2 QSSPSPAHPQLPVLQTQMVSDGMTGSNPVSPASSSSPASSGAGGISPQHIAQDSSLDGPP 61
Query: 759 APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH 790
P A PL+G S + L ++ P + H
Sbjct: 62 GPPDGATVPLEGFSLSQAADLANKGPKWEKSH 93
Score = 32.0 bits (71), Expect = 4.8
Identities = 46/232 (19%), Positives = 76/232 (32%), Gaps = 29/232 (12%)
Query: 1337 PATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVG 1396
P + K P P G + + P + E L P LPL + +
Sbjct: 2594 PVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLE 2653
Query: 1397 GPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVED-ELYQRMLKGPPPEPAASA 1455
P + A P P + D + L E Q ++ P+ S+
Sbjct: 2654 LPPS--------AASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSS 2705
Query: 1456 AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQ-- 1513
+ T P+ +P PP +R ++ Q + P + L + +++ ++
Sbjct: 2706 S-ATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELV 2764
Query: 1514 -------------APG---RTPAPSYPHAASAGTPASPPPLHRP-EAYPPSS 1548
PG + +P P S P S PP+ P EA P SS
Sbjct: 2765 RRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSS 2816
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 130 bits (328), Expect = 8e-30
Identities = 176/631 (27%), Positives = 210/631 (33%), Gaps = 122/631 (19%)
Query: 416 APALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLP 475
+P + V PP PP PPGA S P + ++ S IV P + + Q P
Sbjct: 747 SPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQT-KFCSEISLIVSPRR--ISVQLDSHQP 803
Query: 476 GAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSG 535
Q P S L + GQ + PH+ +
Sbjct: 804 TQSISQPPPPPSLLWSAGQGQ-PGSQPPHS-----------------------ISTEFQT 839
Query: 536 AHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAM 595
+H + SA P+ +P + ++ S+P P P L G+T+P
Sbjct: 840 SHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPP----LPGMTVPTLPSTA 895
Query: 596 LNTPDGL----VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAP 651
+ P L + P P G P P P P A PLP P A PP P
Sbjct: 896 IPQPPPLQGTEMLPPPPPPLPGAGIP-----PPPPLPGAGILPLP---PLPGAGIPPPPP 947
Query: 652 TPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA 711
P AA PP P P G+ P G PP PL
Sbjct: 948 LPGAAIPP--PPPLPGAGIPLPPPLPGAGIPP----------------------PPPLPG 983
Query: 712 EG--PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA--- 766
G P +P + I PP P P GAG+ P P A P P +P A
Sbjct: 984 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
Query: 767 --PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPP 824
PL G G P LP G P P P PP PP P + PP P PP
Sbjct: 1044 PPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPP 1098
Query: 825 PQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA--PHLPPS 882
PP LPG+ G+PPP P P A PP PPL PP PLP A P PP
Sbjct: 1099 ---PPPLPGV-------GIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPP------ 936
+ +P P P PP P PPP L V P PP
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGI 1206
Query: 937 PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPA 996
PPPP M P PA P P P G G P P S PL
Sbjct: 1207 PPPPPLPGMGIPPAPAPPLP----------PPGT-------GIPPPPLLPVSGPPLLPQV 1249
Query: 997 ASVLVSGQAPSGTPTAPSHAPAPAPMAATGL 1027
G + TP P P P GL
Sbjct: 1250 ------GSSTLPTPQVCGFLPPPLPSGLFGL 1274
Score = 93.2 bits (230), Expect = 2e-18
Identities = 168/673 (24%), Positives = 215/673 (31%), Gaps = 143/673 (21%)
Query: 204 GNVTLQPIPGLQGLPNGSPGGATAA-TLGLAPIQVVGQP-----VMALNTPTSQLLAKQV 257
G +TL P+ GL G P PG + T + I ++ P + + PT + Q
Sbjct: 753 GVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSI--SQP 810
Query: 258 PVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPT 317
P L +AG +P + +S + Q + +V+ S F + +P
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTE-----FQTSHEHSVS------SAFKNSCNIPSPP 859
Query: 318 GTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLY--QLTPKPFAPAG 375
P + + PGLG P P P L P P A PP L ++ P P P
Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPP---LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL- 915
Query: 376 ATLTIQGEPGA-LPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA 434
PGA +P P P A + PP G
Sbjct: 916 --------PGAGIPPPPPLPG-------------------------AGILPLPPLPGAGI 942
Query: 435 APPQP-PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANV 493
PP P PGA IP LPG L P P +P P +
Sbjct: 943 PPPPPLPGA----------------AIPPPPPLPGAGIPLPPPLPGAGIPP-----PPPL 981
Query: 494 GGQILAAAAPHTGGQLIANPILTNQNLAGPLSL-GPVLAPHSGAHSAHILSAAPIQ-VGQ 551
G + P G + P L + P L G + P A I P+ G
Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041
Query: 552 PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAA 611
P P L +P AG L G +PP P + P P
Sbjct: 1042 PP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPG 1093
Query: 612 TGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLA 671
G P P P V P P L P A PP P P A PP P P G+
Sbjct: 1094 AGI--------PPPPPLPGVGIPPPPPL--PGAGIPPPPPLPGAGIPPPP--PLPGAGIP 1141
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG--PHLSVPASVIVSAPPP 729
P +G PP PL G P +P + I PP
Sbjct: 1142 PPPPLPRVGIPPPP----------------------PLPGAGIPPPPPLPGAGIPPPPPL 1179
Query: 730 AQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSP 789
P P G G+ P P P IP PL G G +P+ P P P
Sbjct: 1180 PGVGIPPPPPLPGVGIPPPPP------LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233
Query: 790 HLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849
P P P S PP PQ S P + PP P L G+ + Q++ S
Sbjct: 1234 ----PPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDK------GSR 1283
Query: 850 PAPTAPGPPQPPL 862
P P P PL
Sbjct: 1284 KQPIEPCRPMKPL 1296
Score = 80.9 bits (198), Expect = 9e-15
Identities = 132/510 (25%), Positives = 167/510 (32%), Gaps = 91/510 (17%)
Query: 587 TLPPSAVAMLNTP--DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQA 644
T P +L P DGL P P G + PQ L + ++
Sbjct: 746 TSPTEEGGVLTLPPVDGL--PGRPPCPPG-------AESGPQTKFCSEISLIVSPRRISV 796
Query: 645 QQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704
Q PT + PP P P L S + GQP S P +I T+
Sbjct: 797 QLDSHQPTQSISQPP------PPPSLLWSAGQ---GQPGSQPPHSISTE----------- 836
Query: 705 SQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGA-GLGPQAPDSQASPAPAPQIP 763
H SV ++ S P+ P P T + GLG P P P +P
Sbjct: 837 ----FQTSHEH-SVSSAFKNSCNIPSPPPLPCTESSSSMPGLG-------MVPPPPPPLP 884
Query: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP 823
P S ++P PL + LP P P P + P P P + P P
Sbjct: 885 GMTVPTLP----STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP-----PLPGAGILPLP 935
Query: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA--PHLPP 881
P LPG G+PPP P P A PP PPL P PLP A P PP
Sbjct: 936 P------LPGA-------GIPPPP--PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Query: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL---HLVPEPAAP--- 935
+ + +P P P PP P PPP L + P P P
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 936 -PPPPPRTFQMVTTPFP----ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLG 990
PPPPP + P P +P P L P + AG P P +
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIP 1097
Query: 991 P------LTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPT 1044
P + P L P P + P P P+ G+PP P P
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP-PP 1156
Query: 1045 LNVAKAASSGPGKPSGLQYESKLSGLKKPP 1074
L A P +G+ L G+ PP
Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
Score = 62.4 bits (150), Expect = 3e-09
Identities = 193/845 (22%), Positives = 289/845 (34%), Gaps = 132/845 (15%)
Query: 693 QDSLQMFLPQERSQQPLS-AEGPHLSVPASVIVSAPPPAQDPAPATPV---------AKG 742
Q LQ+ L Q++ QQ L AE P +APP A P P + + G
Sbjct: 210 QQQLQLQLQQQQQQQQLQGAEEP----------AAPPTAVSPQPGAFLGLDRFLLGPSGG 259
Query: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
AG P +PD++ + + +P + + P PS P P+ ++P LP+ P S
Sbjct: 260 AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPS-PGGLPVSEAPSLPAAQPAAKDS- 317
Query: 803 PPSRPQSVSRP-PSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQ-- 859
P S + P P P AP G + + A +P P+
Sbjct: 318 ----PSSTAFPFPEAGPGEEAAG--APVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVG 371
Query: 860 --PPLRPQSQPPE---GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ 914
P R +P E GP PA P S + + P + + P+
Sbjct: 372 EDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNH 431
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
P +SP P + PEP+ + T ++ P + H+ G+
Sbjct: 432 SPSQSPNQSPRIKRRPEPSLS--------RGSRTALASVAAP----AKKHRADGGL---- 475
Query: 975 KAGGAPAAPQTSTSLG---PLTSPAASVLVSGQA-PSGTPTAPSHAPAPAPMAATGLPPL 1030
A G + + LG P +A +L G A SG +P+ A A+G P
Sbjct: 476 -AAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALA-----AKASGAPAA 529
Query: 1031 LPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHK 1090
F + +GP + + E S + L P + CF E ++
Sbjct: 530 ADGFQNVFTGRTLLEKLFSQQENGPPE----EAEKFCSRIIAMGLLLPFSD-CFREPCNQ 584
Query: 1091 H---QGSVLHPDYKTAFPSFEDALHRL------LPYHVYQGALPS--PSDYHKVD----E 1135
+ + D + + H L P V PS P + H+++ E
Sbjct: 585 NAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAETE 644
Query: 1136 EFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMID-RMFIQE-EKTTLALDKQL 1193
VS KR+ A+ + + E V E + D R I E E+ ALD ++
Sbjct: 645 SQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEV 704
Query: 1194 AK--EKPDEYVSSSRSLGLPIAASSE----GHRLPGHGPLSSSAP---GASTQPP-PHLP 1243
A + + V++S + L E HR+ + +S G T PP LP
Sbjct: 705 ASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLP 764
Query: 1244 TKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEAR 1303
+ G G + + S +S S + LD+ + S+ PP +
Sbjct: 765 GRPPCPPGAESGPQT----KFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSA 820
Query: 1304 SR----------IGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPR---PP 1350
+ I + + E +S N+ P PPP P T + P PP
Sbjct: 821 GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIP--SPPPLPCTESSSSMPGLGMVPP 878
Query: 1351 PPPPPTGQMNGTVDHPPPAAPERKPL-GT---APHCPRLPLRKTYRENVGGPGAPEGTPA 1406
PPPP G T+ P A P+ PL GT P P LP G G P P
Sbjct: 879 PPPPLPGMTVPTL--PSTAIPQPPPLQGTEMLPPPPPPLP----------GAGIPPPPPL 926
Query: 1407 GRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEA 1466
A PLP L L + PPP P A P
Sbjct: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP---PPPLPG 983
Query: 1467 PGLPP 1471
G+PP
Sbjct: 984 AGIPP 988
Score = 60.8 bits (146), Expect = 1e-08
Identities = 84/320 (26%), Positives = 125/320 (39%), Gaps = 39/320 (12%)
Query: 610 AATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPG 669
+AT + + +Q A + L L LQQ Q QQ Q + AAPP A +PQ PG
Sbjct: 188 SATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQG-AEEPAAPPTAVSPQ--PG 244
Query: 670 LASSPEKIVLGQPPSA--TPTAILTQDSLQMF--LPQERSQQPLSAEGPHLSVPASVIVS 725
++ +LG A P + T+ +L LP+ + +P + P P + VS
Sbjct: 245 AFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQP--PSPGGLPVS 302
Query: 726 APP--PAQDPAPATPVAKGAGLGPQA-PDSQASPAPA-----------PQIPAAAPLKGP 771
P PA PA + A P+A P +A+ AP AP P
Sbjct: 303 EAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSP 362
Query: 772 GPSSSPSLPHQAP--LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPP 829
G +P + AP LG+ P ++ P P + S P S P C P
Sbjct: 363 GEEWAPEVGEDAPQRLGEEP--------EEEAQGPDAPAAASLPGSPAPSQRCFKPYPLI 414
Query: 830 TLPGIFVIQNQLGVP--PPASNP--APTAPGPPQPPLRPQSQPPEGPL--PPAPHLPPSS 883
T I QL P P+ +P +P P+P L S+ + P H
Sbjct: 415 TPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGG 474
Query: 884 TSSAVASSSETSSRLPAPTP 903
++ ++ S++ + L A TP
Sbjct: 475 LAAGLSRSADWTEELGARTP 494
Score = 43.9 bits (102), Expect = 0.001
Identities = 75/272 (27%), Positives = 85/272 (31%), Gaps = 43/272 (15%)
Query: 1210 LPIAASSEGHRLPGHG-PLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSL 1268
LP AA LPG G PL PGA PPP LP GAG P A
Sbjct: 948 LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP--------GAGIPPPPPLPGAGIPP 999
Query: 1269 SSSSSSSSAASSLDADEDG-----PMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVH 1323
+ G P+P PP G + + +
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-----GAGIPPPPPLPGAGIPP 1054
Query: 1324 NTALDPVHQPPPPPAT-LKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379
L PPPPP + PPP P PPPPP + G PPP P +G
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLP---GVGIP 1108
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P P LP G G P P A P PLP L R L
Sbjct: 1109 PP-PPLP----------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPP 1471
+ PPP P A P G+PP
Sbjct: 1158 PGAGIPPPPPLPGAGIPP---PPPLPGVGIPP 1186
Score = 43.1 bits (100), Expect = 0.002
Identities = 61/209 (29%), Positives = 69/209 (33%), Gaps = 62/209 (29%)
Query: 1221 LPGHG-PLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAAS 1279
LPG G P PGA PPP LP GAG P R
Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLP--------GAGIPPPPPLPRVG-------------- 1150
Query: 1280 SLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPAT 1339
P+P PP AG+ L V PPPPP
Sbjct: 1151 ---IPPPPPLPGAGIPPPPPLPG-------------AGIPPP---PPLPGVGIPPPPPLP 1191
Query: 1340 -LKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPERKPLGTA-PHCPRLPLRKTYREN 1394
+ + PPP P PPPPP M PP AP P GT P P LP+
Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMG----IPPAPAPPLPPPGTGIPPPPLLPVS------ 1241
Query: 1395 VGGPGAPE----GTPAGRARGGSPAPLPA 1419
G P P+ P + G P PLP+
Sbjct: 1242 -GPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269
Score = 42.7 bits (99), Expect = 0.003
Identities = 44/142 (30%), Positives = 52/142 (36%), Gaps = 15/142 (10%)
Query: 1333 PPPPPATLKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRK 1389
PPPP + + PPP P PPPPP + G PPP P + P PR+ +
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLP-GAGIPPPPPLPRVGIPP 1153
Query: 1390 TYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPP 1449
+ G G P P A P PLP L L + PPP
Sbjct: 1154 P--PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
Query: 1450 EPAASAAQGTGDPDWEAPGLPP 1471
P G G P AP LPP
Sbjct: 1212 LP------GMGIPPAPAPPLPP 1227
Score = 40.0 bits (92), Expect = 0.018
Identities = 50/174 (28%), Positives = 64/174 (36%), Gaps = 44/174 (25%)
Query: 890 SSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTP 949
S + + RL QLQ Q + L EPAAPP
Sbjct: 197 SDIQQAIRLQQQQQQQLQLQLQQQQQQQQ-------LQGAEEPAAPPTA----------- 238
Query: 950 FPALPQPKALL--ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPS 1007
PQP A L +RF PSG AG AP +P T +L L+ S+ +
Sbjct: 239 --VSPQPGAFLGLDRFLLGPSG-----GAGEAPGSPDTEQALSALSDLPESL-------A 284
Query: 1008 GTPTAPSHAPAPAPMAATGLP----PLLPAENKAFASNLPTLNVAKAASSGPGK 1057
P P P+P GLP P LPA A A + P+ +GPG+
Sbjct: 285 AEPREPQQPPSPG-----GLPVSEAPSLPAAQPA-AKDSPSSTAFPFPEAGPGE 332
Score = 37.0 bits (84), Expect = 0.15
Identities = 71/284 (25%), Positives = 103/284 (36%), Gaps = 42/284 (14%)
Query: 529 VLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL 588
+L P GA A + + AL +P SLAA Q P+P G V + +L
Sbjct: 253 LLGPSGGAGEAP--GSPDTEQALSALSDLPESLAAEPREPQQPPSPGG---LPVSEAPSL 307
Query: 589 PPSAVAMLNTPDGLVQPATPAAATGE---AAPVL------------TVQPAPQAPPAVST 633
P + A ++P P P A GE APV + AP+ P
Sbjct: 308 PAAQPAAKDSPSSTAFP-FPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEW 366
Query: 634 PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQ 693
+G PQ Q P A + SP +P + P TP I T
Sbjct: 367 APEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSP----APSQRCFKPYPLITPCYIKT- 421
Query: 694 DSLQMFLP-----QERSQQPLSAEGPHLSV---PASVIVSAPPPAQDPAPATPVAKGAGL 745
+ Q+ P Q +Q P P S+ + + S PA+ +A AGL
Sbjct: 422 TTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLA--AGL 479
Query: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSS------SPSLPHQA 783
A ++ A P++ +A L G +S SP+L +A
Sbjct: 480 SRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKA 523
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 129 bits (324), Expect = 2e-29
Identities = 104/401 (25%), Positives = 144/401 (35%), Gaps = 55/401 (13%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQP--- 623
P + P+P P +TT L T P TP P+ P T P T P
Sbjct: 1401 PPTTTPSPP-PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459
Query: 624 APQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPP 683
PP +TP P P PT PP TTP P +P PP
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPP 1519
Query: 684 SATPTAILTQDSLQ--MFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAK 741
+ TP+ T + P + P++ ++P + S PP P T
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP- 1578
Query: 742 GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801
+P + +P+P P I P P+++PS P + +P PT PS
Sbjct: 1579 -------SPPTTTTPSP-PTITTTTP----PPTTTPSPP-------TTTTTTPPPTTTPS 1619
Query: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861
P + P ++ P S L P P PPT PPP + P+P P PP
Sbjct: 1620 PPTTTP--ITPPTSTTTLPPTTTPSPPPTTTT---------TPPPTTTPSPPTTTTPSPP 1668
Query: 862 LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ-LQFPPSQGPHKSP 920
+ + PP P PSS + S T+ P+PT + + + +P
Sbjct: 1669 ITTTTTPP-------PTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTP 1721
Query: 921 TPPPTLHLVPEPAAPPPPPPRTF----------QMVTTPFP 951
+PPPT P P P PP T + TTP P
Sbjct: 1722 SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762
Score = 125 bits (315), Expect = 2e-28
Identities = 101/391 (25%), Positives = 149/391 (38%), Gaps = 49/391 (12%)
Query: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707
P PT + PP +TT P S P PP+ TP+ +T + +
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT---------TPP 1449
Query: 708 PLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS---PAPAPQIPA 764
P + P +S + PPP P+P T P P + + P P P
Sbjct: 1450 PTTTPSPPIST-----TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT 1504
Query: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPP 824
P+ P S++ P P + +P PT PS P + P ++ P S L P
Sbjct: 1505 TTPITPPA-STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP--ITPPTSTTTLPPTTT 1561
Query: 825 PQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSST 884
P PPT PPP + P+P P PP + PP P PP++T
Sbjct: 1562 PSPPPT---------TTTTPPPTTTPSPPTTTTPSPPTITTTTPP----PTTTPSPPTTT 1608
Query: 885 SSAVASSSETSSRLPAP-TPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRT- 942
++ ++ S P TP PP+ +P+PPPT P P P PP T
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPT----TTPSPPPTTTTTPPPTTTPSPPTTTT 1664
Query: 943 ----FQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAAS 998
TTP P P + + P+ + P++P T+T T+P+++
Sbjct: 1665 PSPPITTTTTP-PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT-----TTPSST 1718
Query: 999 VLVSGQAPSGTPTAPSHAPAPAPMAATGLPP 1029
S + T +P+ P+P T LPP
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749
Score = 99.8 bits (247), Expect = 2e-20
Identities = 196/957 (20%), Positives = 282/957 (29%), Gaps = 143/957 (14%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 3485
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 3486 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 3542
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 3543 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3643
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3644 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3696 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3738
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3847
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3848 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3905
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3906 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3964
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3965 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 4015
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 4016 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 4074
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 4133
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193
Query: 960 L----ERFHQVPSGIILQNKAGGAPAAPQTSTSL-GPLTSPAA-------SVLVSGQAPS 1007
P + + + PQTS S PLT ++ ++ AP
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP 4253
Query: 1008 GTPTAPS-----HAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
TPTAP+ H +P P T P +S+ PT + + ++ P+
Sbjct: 4254 STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT 4310
Score = 97.8 bits (242), Expect = 7e-20
Identities = 101/395 (25%), Positives = 141/395 (35%), Gaps = 62/395 (15%)
Query: 723 IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQ 782
I + PP P+P P + P P P P P+++PS P
Sbjct: 1396 ITTPSPPTTTPSP-----------PPTSTTTLPPTTTPSPPTTTTTTPP-PTTTPSPPIT 1443
Query: 783 APLGDSP-HLPSP----HPTRPPSRPPSRPQSVSRPPSEPPLHP-----CPPPQAPPTLP 832
P PSP T PP+ PS P + PP+ P P PPP P+ P
Sbjct: 1444 TTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPP 1503
Query: 833 GIFVIQNQLGVPPPASN---PAPTAPGPP------QPPLRPQSQPPEGPLPP---APHLP 880
+ PPAS P T P PP PP S P P+ P LP
Sbjct: 1504 ------TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1557
Query: 881 PSSTSSAVASSSETSSRLPAPTPSDFQLQFPP-----SQGPHKSPTPPPTLHLVPEPAAP 935
P++T S +++ T P+P PP + P +P+PP T P P
Sbjct: 1558 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT 1617
Query: 936 PPPP---PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP-QTSTSLGP 991
P PP P T TT P P P P+ P T+T+ P
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 992 LTSPAASVLVSGQAPSGTPTAPSHAPAP-APMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
T+P++ + + P+ T T PS P +P+ T P + S PT +
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTP-----SSTTTPSPPPTTMTTPS 1732
Query: 1051 ASSGPGKPSGLQ-------YESKLSGLKKPPTLQP 1078
++ P P+ S L+ PP++ P
Sbjct: 1733 PTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767
Score = 93.2 bits (230), Expect = 2e-18
Identities = 197/959 (20%), Positives = 276/959 (28%), Gaps = 148/959 (15%)
Query: 174 TVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLGL 232
T T P + +V P P G T PI + P +P G T
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-- 1944
Query: 233 APIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSPQ 283
PI V TPT P++ P+ P+T + V+P
Sbjct: 1945 TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPT 2002
Query: 284 GAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPNV 342
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2003 PTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2051
Query: 343 ILHRTPT--PIQ--------PKPAGVLPPKLYQLT------PKPFAPAGA--------TL 378
+TPT PI P P G P +T P P P G T
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2110
Query: 379 TIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQ 438
T P P + P ++ P P P TTT P
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164
Query: 439 PPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQIL 498
P P + + ++ V P P P + ++ P G Q
Sbjct: 2165 TPTGTQTPTTTPITT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-- 2216
Query: 499 AAAAPHTGGQLIANPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
P T PI T + P G + + ++ P G
Sbjct: 2217 ---TPTT------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2267
Query: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAP 617
P++ PT + P T + T+ P+ TP G P T T
Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT----- 2317
Query: 618 VLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPG 669
TV P P P TP + P PTP P T TP P+P
Sbjct: 2318 TTTVTPTP-TPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPT 2374
Query: 670 LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVI 723
+P + + TPT T P + P + P + P +
Sbjct: 2375 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTT 2433
Query: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLP 780
+ P TP P + +P P P Q P P+ +++ P
Sbjct: 2434 TTVTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTP 2484
Query: 781 HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLP 832
P G +P T P P P + P + P P P Q P T P
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544
Query: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892
I P P PT + P G P P ++T++ + +
Sbjct: 2545 -ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPT 2602
Query: 893 ETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA 952
T ++ P TP P+ P + TP T P P P T TTP
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662
Query: 953 ------LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL------ 1000
P P Q P+ + P T T P T+P +
Sbjct: 2663 TTTVTPTPTPTGT-----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP 2716
Query: 1001 --VSGQAPSGTP--TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
Q P+ TP T + P P P T P P + PT + ++ P
Sbjct: 2717 TPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2105
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2106 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2162
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2163 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 2263
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 2264 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 2316 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 2358
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 2467
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 2468 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2525
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 2584
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 2585 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 2635
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 2636 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 2694
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 2814 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 2868 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2243
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2244 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2300
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2301 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 2401
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 2402 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2453
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 2454 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 2496
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 2605
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 2606 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 2722
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 2723 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 2773
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 2832
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 2891
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 2952 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3005
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3006 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2381
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2382 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2438
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2439 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 2539
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 2540 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 2592 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 2634
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 2743
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 2744 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2801
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 2802 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 2860
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 2861 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 2911
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 2970
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3029
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3090 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3143
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3144 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2519
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2520 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2576
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2577 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 2677
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 2678 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2729
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 2730 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 2772
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 2881
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 2882 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2939
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 2940 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 2998
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 2999 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3049
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3050 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3108
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3167
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3228 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3282 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2657
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2658 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2714
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2715 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 2815
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 2816 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 2868 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 2910
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3019
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3020 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3077
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3136
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3137 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3187
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3188 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3246
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3366 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3420 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2795
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2796 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2852
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2853 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 2953
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 2954 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3005
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3006 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3048
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3157
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3158 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3216 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3274
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3275 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3325
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3326 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3384
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3443
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3504 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3558 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 2933
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 2934 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 2990
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 2991 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3091
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3092 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3143
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3144 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3186
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3295
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3296 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3353
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3412
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3413 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3463
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3464 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3522
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3581
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3642 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3696 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 3071
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 3072 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 3128
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 3129 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3229
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3230 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3282 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3324
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3433
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3434 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3491
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3550
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3551 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3601
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3602 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3660
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3719
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3720 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3779
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3780 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3833
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3834 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 3209
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 3210 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 3266
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 3267 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3367
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3368 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3420 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3462
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3571
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3572 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3629
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3688
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3689 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3739
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3798
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3857
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3858 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3917
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 3918 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 3972 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016
Score = 92.4 bits (228), Expect = 3e-18
Identities = 193/946 (20%), Positives = 273/946 (28%), Gaps = 143/946 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 3347
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 3348 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 3404
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 3405 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3505
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3506 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3558 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3600
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3709
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3710 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3767
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
+ TPT T P + P + P + P + + P
Sbjct: 3768 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQ 3826
Query: 737 TPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
TP P + +P P P Q P P+ +++ P P G +
Sbjct: 3827 TPTTT-----PITTTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTT 3877
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP---QAPPTLPGIFVIQNQLGVPP 845
P T P P P + P + P P P Q P T P I P
Sbjct: 3878 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 3936
Query: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
P PT + P G P P ++T++ + + T ++ P TP
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 3995
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LPQPKAL 959
P+ P + TP T P P P T TTP P P
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4055
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAPSGTP- 1010
Q P+ + P T T P T+P + Q P+ TP
Sbjct: 4056 -----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 4109
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
T + P P P T P P + PT + ++ P
Sbjct: 4110 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154
Score = 91.7 bits (226), Expect = 5e-18
Identities = 89/341 (26%), Positives = 119/341 (34%), Gaps = 69/341 (20%)
Query: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPA-------TPAA 610
P S PT + P PA+TT L T P TP P+ TP
Sbjct: 1494 PPPTTTPSPPTTTPITP--PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1551
Query: 611 ATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGL 670
+T P T P P +TP P P P PT PP TTP P
Sbjct: 1552 STTTLPPTTTPSPPPTT---TTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT 1608
Query: 671 ASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPA 730
++P PP+ TP +T + LP + P + PPP
Sbjct: 1609 TTTPPPTTTPSPPTTTP---ITPPTSTTTLPPTTTPS-----------PPPTTTTTPPPT 1654
Query: 731 QDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH 790
P+P T + P+P I P P+++PS +P+ +P
Sbjct: 1655 TTPSPPT-----------------TTTPSPPITTTTT---PPPTTTPS----SPITTTPS 1690
Query: 791 LPSPHPTRP-PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849
P+ T P P+ PS P + + PS P PPP T P P +
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTT-PSPPPTTMTT-------------PSPTTT 1736
Query: 850 PA-PTAPGPPQPPLRPQSQPPEGPLPPA---PHLPPSSTSS 886
P+ PT PP S PLPP+ P P ST++
Sbjct: 1737 PSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTT 1777
Score = 85.5 bits (210), Expect = 4e-16
Identities = 163/786 (20%), Positives = 231/786 (29%), Gaps = 108/786 (13%)
Query: 316 PTGTPSGQPLAVA---PGLGSSP---LVPAPNVILHRTP----TPIQPKPAGVLPPKLYQ 365
PT TPS P P SP P+P + TP TP P PP
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM 1696
Query: 366 LTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFK 425
TP P + +T P + P +T + P+P +
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTT---------PSPPT-TTMTT 1746
Query: 426 QPPATTTG--AAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLP 483
PP TT+ P PP S ++ +P L +L G P P
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP----LCNWTGWLDSGKPNFHKP 1802
Query: 484 QQLSALPANVGGQILAAAAPHTGGQLIANPI-LTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
+ L +V G AA PI Q + +S+G ++ + ++
Sbjct: 1803 GGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVG-LICKNEDQKPGGVI 1861
Query: 543 SAA-----PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLN 597
A I V P ++ + + P TT + P
Sbjct: 1862 PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTT 1921
Query: 598 TPDGLVQPATPAAA-TGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA 656
TP TP TG P T P TP P G Q PT
Sbjct: 1922 TPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQ---------TPTTTPI 1970
Query: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
TP P+P +P + + TPT T Q + P++
Sbjct: 1971 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-------QTPTTTPITT----- 2018
Query: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAP---QIPAAAPLKGPGP 773
+ + P P P T P + +P P P Q P P+
Sbjct: 2019 ---TTTVTPTPTPTGTQTPTTT--------PITTTTTVTPTPTPTGTQTPTTTPIT---- 2063
Query: 774 SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP-----PLHPCPPP--- 825
+++ P P G +P T P P P + P + P P P
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2123
Query: 826 QAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS 885
Q P T P I P P PT + P G P P ++T+
Sbjct: 2124 QTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTT 2181
Query: 886 SAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQM 945
+ + + T ++ P TP P+ P + TP T P P P T
Sbjct: 2182 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241
Query: 946 VTTPFPA------LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASV 999
TTP P P Q P+ + P T T P T+P +
Sbjct: 2242 TTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTT 2295
Query: 1000 L--------VSGQAPSGTP--TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAK 1049
Q P+ TP T + P P P T P P + PT +
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQ 2354
Query: 1050 AASSGP 1055
++ P
Sbjct: 2355 TPTTTP 2360
Score = 84.3 bits (207), Expect = 8e-16
Identities = 171/812 (21%), Positives = 245/812 (30%), Gaps = 116/812 (14%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 3646
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 3647 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 3703
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 3704 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3804
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3805 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3857 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3899
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3959
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 4008
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 4009 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4066
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLS--VPASVIVSAPPPAQDPA 734
+ TPT T P + P + P + + + P P
Sbjct: 4067 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126
Query: 735 PAT-PVAKGAGLGPQ-APDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL- 791
P T P+ + P P +P P P P+ + + P P+ + +
Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 4185
Query: 792 PSPHPTRPPSRPPSRPQSV---SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848
P+P PT + PP+ + S PP P + T + L PPA
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 4245
Query: 849 NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSS--AVASSSETSSRLPAPTPSDF 906
TAP P P P + L P PPS+T+S + T+ APTPS
Sbjct: 4246 EMTSTAP--PSTPTAPTTTSGGHTLSP----PPSTTTSPPGTPTRGTTTGSSSAPTPSTV 4299
Query: 907 QLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
Q + P +PTP T ++ P P
Sbjct: 4300 QTTTTSAWTP--TPTPLSTPSIIRTTGLRPYP 4329
Score = 81.3 bits (199), Expect = 7e-15
Identities = 189/920 (20%), Positives = 275/920 (29%), Gaps = 144/920 (15%)
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGL-PNGSPGGATAATLG 231
PT P + +V P P G T PI + P +P G T
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT- 3623
Query: 232 LAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE---------PVTLASAGVSP 282
PI V TPT P++ P+ P+T + V+P
Sbjct: 3624 -TPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTP 3680
Query: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSG-QPLAVAPGLGSSPLVPAPN 341
Q + + TT PT TP+G Q P ++ + P P
Sbjct: 3681 TPTPTGTQTPTTTPITTT-----------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 342 VILHRTPT--PIQ--------PKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQP 391
+TPT PI P P G P +T T T+ P Q
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQT 3781
Query: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
+T ++ P P P TTT P P P + +
Sbjct: 3782 PTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3833
Query: 452 LNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
++ V P P P + ++ P G Q P T
Sbjct: 3834 TT--TTTVTPT----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTT------ 3876
Query: 512 NPILTNQNLAG-PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PI T + P G + + ++ P G P++ PT +
Sbjct: 3877 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
P T + T+ P+ TP G P T T TV P P P
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITT-----TTTVTPTP-TPTG 3985
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--------TPQPSPGLASSPEKIVLGQP 682
TP + P PTP P T TP P+P +P +
Sbjct: 3986 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4043
Query: 683 PSATPTAILTQDSLQMFLPQERSQQ------PLSAEGPHLS--VPASVIVSAPPPAQDPA 734
+ TPT T P + P + P + + + P P
Sbjct: 4044 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4103
Query: 735 PAT-PVAKGAGLGPQ-APDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL- 791
P T P+ + P P +P P P P+ + + P P+ + +
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 4162
Query: 792 --PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849
P+P T+ P+ P + P P PP T P + + PPP S+
Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAP---IAELTTSNPPPESS 4219
Query: 850 PAPTAPGPPQPPLRPQSQPPEGPLPPAPHL----PPSS-TSSAVASSSETSSRLPAPTPS 904
T+ P +S LPPA + PPS+ T+ S T S P+ T S
Sbjct: 4220 TPQTSRSTSSP--LTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS 4277
Query: 905 DFQLQFPP-------SQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTT----PFPAL 953
PP + G +PTP P P P T ++ T P+P+
Sbjct: 4278 ------PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSS 4331
Query: 954 PQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLG----PLTSPAASVLVSGQAPSGT 1009
+L + P + G S S + P+ PS T
Sbjct: 4332 VLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST--------PSPT 4383
Query: 1010 PTAPSHAPAPAPMAATGLPP 1029
PT P P+ ++T P
Sbjct: 4384 PTPSKSTPTPSKPSSTPSKP 4403
Score = 80.5 bits (197), Expect = 1e-14
Identities = 80/294 (27%), Positives = 109/294 (37%), Gaps = 38/294 (12%)
Query: 814 PSEPPLHPCPPPQAPPTLPGIFVIQ---NQLGVPPPASNPAP-----TAPGP---PQPPL 862
PS P P PPP + TLP PPP + P+P T P P P PP+
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 863 RPQSQPPEGPLPPAPHLPPSSTSS---AVASSSETSSRLPAPT-----PSDFQLQFPPSQ 914
+ PP P PP++T S S T++ P PT P+ + P S
Sbjct: 1459 STTTTPPPTTTPS----PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 915 ---GPHKSPTPPPTLHLVPEPAAPPPPP---PRTFQMVTTPFPALPQPKALLERFHQVPS 968
P +P+PP T P P P PP P T TT P P P
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Query: 969 GIILQNKAGGAPAAPQ-TSTSLGPLTSPA-ASVLVSGQAPSGTPTAPSHAPAPAPMAATG 1026
P+ P T+T+ P T+P+ + + P+ TP+ P+ P P + T
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634
Query: 1027 LPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKL-SGLKKPPTLQPS 1079
LPP S PT ++ P P+ + + PPT PS
Sbjct: 1635 LPP------TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682
Score = 72.0 bits (175), Expect = 4e-12
Identities = 156/771 (20%), Positives = 220/771 (28%), Gaps = 117/771 (15%)
Query: 314 SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAP 373
S PT TPS +P ++ P T TP P + PP P P
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPP-------TTTPSPPTTTPITPPASTTTLPPTTTP 1523
Query: 374 AGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTG 433
+ T T P P +P T + + + + P+P PP TTT
Sbjct: 1524 SPPTTTTTTPP---PTTTPSPPTTTPITPPTSTTTLPPTTTPSP---------PPTTTTT 1571
Query: 434 AAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANV 493
P P P P P P
Sbjct: 1572 PPPTTTPS-------------------PPTTTTPSPPTITTTTPPPTTTP---------- 1602
Query: 494 GGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPA 553
+P T P T P + P+ P S + +P P
Sbjct: 1603 --------SPPTTTTTTPPPTTT----PSPPTTTPITPPTSTTTLPPTTTPSP----PPT 1646
Query: 554 LFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATG 613
P S PT + P+P P TT T PS+ TP+ T
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSP--PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT 1704
Query: 614 EAAPV-LTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLAS 672
++P+ T P+ P +P P + P P PT P TT P L +
Sbjct: 1705 PSSPITTTTTPSSTTTP---SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP---LTT 1758
Query: 673 SPEKIVLGQPPSATP---TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPP 729
+P PPS TP + T +P L + P+ P
Sbjct: 1759 TP------LPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG-DTELIGD 1811
Query: 730 AQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSP 789
P A ++ A + P P Q + K +P L
Sbjct: 1812 VCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEI 1871
Query: 790 HLPSPHPTRPPSRPPSRPQSVSRPPSEPPL------HPCPPP---QAPPTLPGIFVIQNQ 840
++ P+ + PP+ P+ P P P Q P T P I
Sbjct: 1872 NVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTV 1930
Query: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900
P P PT + P G P P ++T++ + + T ++ P
Sbjct: 1931 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPT 1989
Query: 901 PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA------LP 954
TP P+ P + TP T P P P T TTP P
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2049
Query: 955 QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL--------VSGQAP 1006
P Q P+ + P T T P T+P + Q P
Sbjct: 2050 TPTGT-----QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTP 2103
Query: 1007 SGTP--TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
+ TP T + P P P T P P + PT + ++ P
Sbjct: 2104 TTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
Score = 71.6 bits (174), Expect = 5e-12
Identities = 160/794 (20%), Positives = 223/794 (28%), Gaps = 85/794 (10%)
Query: 314 SAPTGTPSGQPLAVAPGLGSSPLV--PAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPF 371
S PT T + P P ++ + PA L T TP P PP T P
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP----TTTPS 1540
Query: 372 APAGATLTIQGEPGALPQQ--PKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQP-- 427
P +T LP P P T + + P+P P
Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT 1600
Query: 428 ---PATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
P TTT PP P S P + + S+ +P P P P
Sbjct: 1601 TPSPPTTTTTTPP-PTTTPSPPTTTPITPPTSTTTLPPT-TTPSPPPTTTTTPPPTTTPS 1658
Query: 485 QLSALPANVGGQILAAAAPHT--GGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
+ + P T + P + P P P S +
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP---SPTTTPSSPITTTTTP 1715
Query: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGL 602
S+ P P S PT + ++ L LPPS +P
Sbjct: 1716 SSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFST 1775
Query: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQP--------QAQQPPQAPTPQ 654
P TP L P T L + P +A P P Q
Sbjct: 1776 TTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQ 1835
Query: 655 AAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQM----FLPQERSQQPLS 710
Q S GL E +P P A + + + Q + +
Sbjct: 1836 LG---QTVVCDVSVGLICKNED---QKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTT 1889
Query: 711 AEG--PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAP---QIPAA 765
E P + P + + P TP P + +P P P Q P
Sbjct: 1890 TENPTPPTTTPITTTTTVTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTT 1944
Query: 766 APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP-----PLH 820
P+ +++ P P G +P T P P P + P +
Sbjct: 1945 TPI----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2000
Query: 821 PCPPP---QAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAP 877
P P P Q P T P I P P PT + P G P
Sbjct: 2001 PTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2059
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP 937
P ++T++ + + T ++ P TP P+ P + TP T P P
Sbjct: 2060 -TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2118
Query: 938 PPPRTFQMVTTPFPA------LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGP 991
P T TTP P P Q P+ + P T T P
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTPTPTPTGTQT-P 2172
Query: 992 LTSPAASVL--------VSGQAPSGTP--TAPSHAPAPAPMAATGLPPLLPAENKAFASN 1041
T+P + Q P+ TP T + P P P T P P +
Sbjct: 2173 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2231
Query: 1042 LPTLNVAKAASSGP 1055
PT + ++ P
Sbjct: 2232 TPTPTGTQTPTTTP 2245
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 7/97 (7%)
Query: 1325 TALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMN---GTVDHPPPAAPERKPLGTAPH 1381
T L P P PPP T PPP P PP T + T PPP P+ T P
Sbjct: 1633 TTLPPTTTPSPPPTT--TTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690
Query: 1382 CPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLP 1418
P + T P +P T + +P+P P
Sbjct: 1691 PPTTTM--TTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725
Score = 38.5 bits (88), Expect = 0.051
Identities = 56/233 (24%), Positives = 71/233 (30%), Gaps = 32/233 (13%)
Query: 1325 TALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPR 1384
T L P P PP T PPP P PP T T PPP P+ T
Sbjct: 1414 TTLPPTTTPSPPTTT--TTTPPPTTTPSPPIT-----TTTTPPPTTTPSPPISTT---TT 1463
Query: 1385 LPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML 1444
P T P P TP+ + P T+ I A+ L
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST-TTLPPTTT 1522
Query: 1445 KGPP------PEPAASAAQGTG---DPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD 1495
PP P P + + T P LPP S P + +P
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT-TTPSPPPTTTTTPPPTTTPSPP 1581
Query: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSS 1548
T T I + TP P+ + T +PPP P PP++
Sbjct: 1582 TTTTPSPPTITT---------TTPPPTTTPSPPTTTTTTPPPTTTPS--PPTT 1623
Score = 37.0 bits (84), Expect = 0.15
Identities = 22/65 (33%), Positives = 23/65 (35%), Gaps = 11/65 (16%)
Query: 1325 TALDPVHQPPPPPATLKVAEP------PPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378
T P P PP T + P PP P PPPT T PPP P T
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT-----TTTTPPPTTTPSPPTTT 1663
Query: 1379 APHCP 1383
P P
Sbjct: 1664 TPSPP 1668
Score = 35.8 bits (81), Expect = 0.33
Identities = 50/236 (21%), Positives = 63/236 (26%), Gaps = 18/236 (7%)
Query: 1319 SKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378
S + T P P PP + PP P PP T T PP P T
Sbjct: 1439 SPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTT 1498
Query: 1379 APHCPRL-----PLRKTYRENVGGPGAPEGTPAGRARGGSPA-PLPAKVDEATSGLIREL 1432
P P P T P P T +P+ P + TS
Sbjct: 1499 TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1558
Query: 1433 AAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSP 1492
PP + T P PP S + +P
Sbjct: 1559 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618
Query: 1493 QDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSS 1548
T T + L P TP+P T +PPP P PP++
Sbjct: 1619 SPPTTTPITPPTSTTTL----PPTTTPSP------PPTTTTTPPPTTTPS--PPTT 1662
Score = 35.8 bits (81), Expect = 0.33
Identities = 36/172 (20%), Positives = 57/172 (33%), Gaps = 10/172 (5%)
Query: 1226 PLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADE 1285
P ++ +P +T P T + P+ T ++ S ++++ + +
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 1286 DGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEP 1345
P + PI T + + S + T P PPP T+ P
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733
Query: 1346 PPRPPPP-------PPPTGQMNGTVDHPPPA--APERKPLG-TAPHCPRLPL 1387
P PP PP T T PP+ P P T P P +PL
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPL 1785
Score = 33.9 bits (76), Expect = 1.3
Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 18/110 (16%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHP-----------PPAAPERKPLGTAPH 1381
PP +T +AE PPP T Q + + P PPA P
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST--APPS 4254
Query: 1382 CPRLPLRKTYRENVGGP----GAPEGTPA-GRARGGSPAPLPAKVDEATS 1426
P P + + P +P GTP G G S AP P+ V T+
Sbjct: 4255 TPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTT 4304
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 127 bits (319), Expect = 8e-29
Identities = 136/550 (24%), Positives = 187/550 (34%), Gaps = 81/550 (14%)
Query: 568 TQSQPA-PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626
T+S P P PA TT + P A T + PA T ++AP +PAP
Sbjct: 252 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-------PAPTTTKSAPTTPKEPAPT 304
Query: 627 AP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
P PA +TP + A P+ PTP P TT +P+P P +P
Sbjct: 305 TPKKPAPTTP------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
TP + P + + P AP ++P+P TP
Sbjct: 359 TTP----------------KEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPT 391
Query: 745 LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP-SPHPTRPPSRP 803
AP + PAP A K P P+++ P +P P P PT P
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451
Query: 804 PSRPQ-----SVSRPPSEPPLHPCP--PPQAPPTLP-GIFVIQNQLGVPPPASNPAPTAP 855
P+ P+ + +P P P P P + PT P + + P PAPT P
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 856 GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQLQFPPSQ 914
P P+ P P PAP P ++ + + T+ + PAP TP + P
Sbjct: 512 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTT----------PFPALPQ--------- 955
P PT P P P P P+ TT P P P+
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630
Query: 956 --PKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP- 1010
P E P G AP P+ L P T+ + S + TP
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSG 1069
TAP+ PAP P P S + T K ++ P + +LS
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 748
Query: 1070 LKKPPTLQPS 1079
P L+ S
Sbjct: 749 EPTPKALENS 758
Score = 125 bits (315), Expect = 2e-28
Identities = 141/533 (26%), Positives = 184/533 (34%), Gaps = 74/533 (13%)
Query: 552 PALFQMPVSLAAGSLPTQ-SQPAPAGP---AATTVLQGVTLPPSAVAMLNTPDGLVQPAT 607
P + P S PT +PAP P A TT + P TP P
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----TP---TTPKE 332
Query: 608 PAAATGEAAPVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP- 664
PA T E AP +PAP AP PA +TP + A P+ P P P TTP
Sbjct: 333 PAPTTKEPAPTTPKEPAPTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIV 724
+P+P S P+ T +A T P + + + P P +
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-----PSPTTTKEPAPTTPKEPAPTTPKK 441
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA-PQIPAAAPLKGPGPSSSPSLPHQA 783
AP ++PAP TP AP + PAP P+ PA K P++ L
Sbjct: 442 PAPTTPKEPAPTTPKEP-------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494
Query: 784 PLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P +P P P PT P P+ P+ + E P P P A P P +
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTP-------KEP 546
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP--PEGPLP-----PAPHLP--PSSTSSAVASSSE 893
P PAPT P P P ++ P P+G P PAP P P+ A ++ E
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 606
Query: 894 TSSRL---PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
+S PAPT P P P PT P P P P T +
Sbjct: 607 PTSTTCDKPAPTT-------PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 951 PALPQPKALLERFHQVPSGIILQNKAGG-------------APAAPQTSTSLGPLTSPAA 997
P P PK L + P+ A AP P+ P T P
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719
Query: 998 SVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
+ VS + PT +P + + P EN +PT A
Sbjct: 720 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772
Score = 123 bits (308), Expect = 2e-27
Identities = 130/518 (25%), Positives = 171/518 (33%), Gaps = 67/518 (12%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD--GLVQPATPAAATGEAAPVLTVQPA 624
PT A P A T +G L TP P P T ++AP +PA
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 625 P----QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG 680
P AP P P ++P A P+ P P P TT + +P P
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307
Query: 681 QPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA 740
+P TP + P + + P + P P ++PAP TP
Sbjct: 308 KPAPTTP----------------KEPAPTTPKEPTPTTPK----EPAPTTKEPAPTTP-- 345
Query: 741 KGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
AP + PAP P+ PA K P P+++ P +P PT
Sbjct: 346 -----KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 800 PSRPPSRPQSVSRPPSEP----PLHPCP--PPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P+ +S P EP P P P + PT P + P PAPT
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-------KKPAPTTPKEPAPT 453
Query: 854 APGPPQP-------PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSD 905
P P P P P+ P P AP P T + + T+ PAP TP +
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 513
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
P P P PT P P P P T + P P P E
Sbjct: 514 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 573
Query: 966 VPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP--TAPSHAPAPAP 1021
P G AP P+ L P T+ + + TP TAP+ PAP
Sbjct: 574 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 633
Query: 1022 MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
P P PT + + A + P KP+
Sbjct: 634 TTPKEPAPTTP------KGTAPT-TLKEPAPTTPKKPA 664
Score = 120 bits (300), Expect = 1e-26
Identities = 178/722 (24%), Positives = 240/722 (33%), Gaps = 140/722 (19%)
Query: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG 375
PT T +P + ++P P P I TP +P P K TPK AP
Sbjct: 216 PTPTTPKEPAS------TTPKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPKEPAP-- 264
Query: 376 ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAA 435
T EP P PK P T K+P TTT +A
Sbjct: 265 ---TTTKEPA--PTTPKEPAPTT-------------------------TKEPAPTTTKSA 294
Query: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG 495
P P PA P PA P++ PA
Sbjct: 295 PTTPKE-------------------PAP---------TTPKKPAPTTPKE----PAPTTP 322
Query: 496 QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALF 555
+ P P T P AP A + AP +PA
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKEPAP------TAPKKPAPTTP-KEPAPTTPKEPA-- 373
Query: 556 QMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEA 615
P + S T +PA P T T P+ + P +P+ T E
Sbjct: 374 --PTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS--PTTTKEP 426
Query: 616 APVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLAS 672
AP +PAP P PA +TP + A P+ P P P TTP +P+P +
Sbjct: 427 APTTPKEPAPTTPKKPAPTTP------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP---T 477
Query: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
+P++ P TPT T + L P++ + P P + P ++
Sbjct: 478 TPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTT-----PEELAPTTPEEPTPTTPEE 529
Query: 733 PAPATPVAKGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSP-H 790
PAP TP A AP++ PAP P+ PA K P P++ P G +P
Sbjct: 530 PAPTTPKA-------AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582
Query: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
L P PT P + P+ + EP C P AP T G + P P
Sbjct: 583 LKEPAPTTP--KKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEP 639
Query: 851 APTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
APT P P + P P L P++T +++S+ PAPT
Sbjct: 640 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK----PAPTT------- 688
Query: 911 PPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT-----TPFPALPQPKALLERFHQ 965
P P P PT P P P PPP T ++ T P P
Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748
Query: 966 VPSGIILQN--KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
P+ L+N K G P +T + P + A + + TP + AP
Sbjct: 749 EPTPKALENSPKEPGVPTT-KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 807
Query: 1024 AT 1025
AT
Sbjct: 808 AT 809
Score = 105 bits (263), Expect = 3e-22
Identities = 188/845 (22%), Positives = 263/845 (31%), Gaps = 143/845 (16%)
Query: 248 PTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVF 307
PTS++LAK P + + GP+ +P+ K TT+
Sbjct: 189 PTSKVLAKPTPKAE--TTTKGPALTTPKEPTPTTPKEPASTTPKE---PTPTTIKSAPTT 243
Query: 308 GGAGAA----SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKL 363
A SAPT P ++P PAP + P P K A P +
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT--KEPAPTTTKSAPTTPKEP 301
Query: 364 YQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423
TPK AP T EP P PK P T P A
Sbjct: 302 APTTPKKPAP-----TTPKEPA--PTTPKEPTPTT------------------PKEPAPT 336
Query: 424 FKQPPATTTGAAPPQP-PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQL 482
K+P TT P +P P A KP P + P PA
Sbjct: 337 TKEPAPTT----PKEPAPTAPKKPAPT----------------TPKEPAPTTPKEPAPTT 376
Query: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
++ S +AP T + P T P P +
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-- 432
Query: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA---GPAATTVLQGVTLPPSAVAMLNTP 599
AP +PA P + + T +PAP PA TT + P A TP
Sbjct: 433 EPAPTTPKKPA----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP-TTP 487
Query: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659
L P TP + AP +PAP P ++ P P + P TP+AAAP
Sbjct: 488 KKLT-PTTPE----KLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAP- 540
Query: 660 QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
T +P+P P +P TP + P + +G
Sbjct: 541 -NTPKEPAPTTPKEPAPTTPKEPAPTTP----------------KETAPTTPKG------ 577
Query: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
+AP ++PAP TP PAP+ A K P ++
Sbjct: 578 -----TAPTTLKEPAPTTP-----------------KKPAPKELAPTTTKEPTSTTCDKP 615
Query: 780 PHQAPLGDSPHLP-SPHPTRPPSRPPSRPQ-----SVSRPPSEPPLHPCPPPQAPPTLPG 833
P G +P P P PT P P+ P+ ++ P P P P AP T G
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 834 IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS--SAVASS 891
+ P APT P P P P+ P P P PP +TS S ++
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAP------TTPKKPAPTTPETPPPTTSEVSTPTTT 729
Query: 892 SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951
E ++ +P S +L P+ ++ P + PAA P T + TT
Sbjct: 730 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 789
Query: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
P + + K T + + T+ S P T
Sbjct: 790 LRTTP--------ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 841
Query: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
+ AP NK + P + ++ P + K + K
Sbjct: 842 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 901
Query: 1072 KPPTL 1076
KP T+
Sbjct: 902 KPKTM 906
Score = 81.3 bits (199), Expect = 7e-15
Identities = 99/438 (22%), Positives = 142/438 (32%), Gaps = 70/438 (15%)
Query: 631 VSTPLPLGLQQPQAQQPPQAPT-----PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
V+TP Q + P+ T P+ + PP + T + + L + E V +
Sbjct: 99 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET-SLTVNKETTV--ETKET 155
Query: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
T T T + + Q + P S +++ P TP A+
Sbjct: 156 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---------TPKAETTTK 206
Query: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS 805
GP + P+ PA+ K P P++ S P +P P+P T+ P
Sbjct: 207 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP------TTPKEPAPTTTKSAPTTPK 260
Query: 806 RPQ--SVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLR 863
P + P P P P P P + APT P P P
Sbjct: 261 EPAPTTTKEPAPTTPKEPAPTTTKEPA--------------PTTTKSAPTTPKEPAPTT- 305
Query: 864 PQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
P+ P P PAP P T T+ + PAPT + P P P
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTP--------TTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 924 PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
PT P P P P P T + + P P P +AP
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT--------------------TKSAP 397
Query: 984 QTSTSLGPLTSPAASVLVSGQAPSGT-PTAPSHAPAPAPMAATGLPPLLPAENKAFASNL 1042
T+ P T+ +A +P+ T AP+ PAP P P E
Sbjct: 398 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 457
Query: 1043 PT-LNVAKAASSGPGKPS 1059
P K A + P +P+
Sbjct: 458 PAPTTTKKPAPTTPKEPA 475
Score = 66.6 bits (161), Expect = 2e-10
Identities = 153/721 (21%), Positives = 214/721 (29%), Gaps = 154/721 (21%)
Query: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPA 374
APT P ++P PAP T +P P P P
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424
Query: 375 GATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA 434
T EP P PK P T PAP K+P TTT
Sbjct: 425 EPAPTTPKEPA--PTTPKKPAPTT-------------PKEPAPTTP----KEPAPTTTKK 465
Query: 435 APPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVG 494
P P +P + P + L P P +L PA
Sbjct: 466 PAPTTP---KEPAPT-----------TPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTT 510
Query: 495 GQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
+ LA P P T P + +AAP +PA
Sbjct: 511 PEELAPTTPE-------EPTPTTPEEPAPTT---------------PKAAAPNTPKEPA- 547
Query: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
P + + T +PAP P T TP G T E
Sbjct: 548 ---PTTPKEPAPTTPKEPAPTTPKETAP--------------TTPKG-----TAPTTLKE 585
Query: 615 AAPVLTVQPAPQ--APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLA 671
AP +PAP+ AP P +P A P+ P P TTP +P+P
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTP 644
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
L +P TP P + P + +GP + AP +
Sbjct: 645 KGTAPTTLKEPAPTTPKK-----------PAPKELAPTTTKGPTSTTSDK---PAPTTPK 690
Query: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+ AP TP P P A P P + + P + P+ H++P +P L
Sbjct: 691 ETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP----PPA 847
S PT P+++ P EP GVP P A
Sbjct: 747 -SAEPT---------PKALENSPKEP------------------------GVPTTKTPAA 772
Query: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ 907
+ P T + R PE ++T++ + S+ ++ T + Q
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832
Query: 908 LQFPPSQGPHKSPTPPP----------TLHLVPEPAAPPPPPPR-TFQMVTTPFPALPQP 956
P K+ T P T ++ +P P R T TTP P P
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 892
Query: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA 1016
+ P + K P P+ TS P +P + + +A T T P+
Sbjct: 893 APKKPTSTKKPKTMPRVRKPKTTP-TPRKMTSTMPELNPTSRI---AEAMLQTTTRPNQT 948
Query: 1017 P 1017
P
Sbjct: 949 P 949
Score = 52.8 bits (125), Expect = 3e-06
Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 43/373 (11%)
Query: 1182 EEKTTLALDKQ-LAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP- 1239
+EKTT A + Q + K + +S+ L P + + P P +P
Sbjct: 167 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 226
Query: 1240 --PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
P PT I+ +P+ A ++ S+ ++ + E P + P
Sbjct: 227 TTPKEPTPTTIK-----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 281
Query: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPT- 1356
T E +K T +P P PA EP P P P PT
Sbjct: 282 TTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 1357 -GQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPA 1415
+ T P P P+ AP P+ P T +E AP TP A +
Sbjct: 330 PKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKE-----PAPT-TPKEPAPTTTKE 379
Query: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR 1475
P P E + E K P P + T +P P P
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
K +P +P++ T + A + + PAP+ P + TP
Sbjct: 440 KKPAP---------TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490
Query: 1536 PPLHRPEAYPPSS 1548
P PE P++
Sbjct: 491 TPT-TPEKLAPTT 502
Score = 48.1 bits (113), Expect = 6e-05
Identities = 56/222 (25%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPER-KPLGTA 1379
NT +P P PA EP P P P P G T+ P P P++ P A
Sbjct: 541 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P + P T + P P+GT AP K T+
Sbjct: 601 PTTTKEPTSTTC--DKPAPTTPKGT----------APTTPKEPAPTT------------- 635
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWE--APGLP--PAKRRKSESPDVDQASFSSDSPQDD 1495
P EPA + +GT + AP P PA + + + S +SD P
Sbjct: 636 --------PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687
Query: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
T E + + PAP+ P + TP +PPP
Sbjct: 688 TPKETAPTT-----------PKEPAPTTPKKPAPTTPETPPP 718
Score = 47.0 bits (110), Expect = 1e-04
Identities = 55/223 (24%), Positives = 79/223 (35%), Gaps = 34/223 (15%)
Query: 872 PLPPAPHLPPSSTSSAVAS---SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
P+ P P LPP+S +S S + ET+ T ++ Q + G K+ + T +
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS---TDGKEKTTSAKETQSI 179
Query: 929 VPEPA----------APPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGG 978
A A P P T TT PAL PK P+ + A
Sbjct: 180 EKTSAKDLAPTSKVLAKPTPKAET----TTKGPALTTPKE--------PTPTTPKEPAST 227
Query: 979 APAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAF 1038
P P +T T+P AP+ T +AP+ PAP P P E
Sbjct: 228 TPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 281
Query: 1039 ASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P K+A + P +P+ + K P KE
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 324
Score = 44.7 bits (104), Expect = 7e-04
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 24/226 (10%)
Query: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379
K T +P P PA EP P P P PT + PA K +A
Sbjct: 355 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK---SA 411
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P P+ P T +E AP TP A P P E +E A
Sbjct: 412 PTTPKEPSPTTTKE-----PAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-- 463
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTE 1499
++ P EPA + + T AP P K+ +P+ + +P+ T
Sbjct: 464 -KKPAPTTPKEPAPTTPKET------APTTP--KKLTPTTPE----KLAPTTPEKPAPTT 510
Query: 1500 HLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYP 1545
+ A + PAP+ P AA+ TP P P E P
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/210 (21%), Positives = 71/210 (33%), Gaps = 10/210 (4%)
Query: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT------PPPTLHLVPEPAAP 935
++++ S +TS++ APT P ++ K P P PT P P
Sbjct: 170 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 229
Query: 936 PPPPPRTFQMV-TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
P P T + TTP P + P+ + A P P +T+ P +
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289
Query: 995 PAASVLVSGQAPSGTPT---APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAA 1051
S + + P+ T AP+ PAP P P E + A
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349
Query: 1052 SSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P KP+ + K P +KE
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Score = 42.4 bits (98), Expect = 0.004
Identities = 70/327 (21%), Positives = 103/327 (31%), Gaps = 46/327 (14%)
Query: 1231 APGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMP 1290
AP A +P P P + +P+ A ++ S ++ + + P
Sbjct: 349 APTAPKKPAPTTPKE---------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399
Query: 1291 SRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPP 1350
++ P T A + K + T +P P PA EP P P
Sbjct: 400 TKEPAPTTTKSAPTTP----KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 455
Query: 1351 PPPPPTGQMNGTVDHPPPAAPERK----PLGTAPHCPRLPLRKTYRENVGGPGAPEG--- 1403
P PT T P P P+ P TAP P+ L T E + P PE
Sbjct: 456 KEPAPT-----TTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLA-PTTPEKPAP 508
Query: 1404 -TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
TP A P P +E + A P EPA + + +P
Sbjct: 509 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-----------NTPKEPAPTTPK---EP 554
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRT---- 1518
P P K +P + + + + T + + + P T
Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614
Query: 1519 PAPSYPHAASAGTPASPPPLHRPEAYP 1545
PAP+ P + TP P P E P
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAP 641
Score = 32.7 bits (73), Expect = 2.8
Identities = 39/177 (22%), Positives = 61/177 (34%), Gaps = 11/177 (6%)
Query: 1337 PATLKVAEPP-PRPPPPPPPTGQMNGTVDHPPPAAPER-KPLGTAPHCPRLPLRKTYREN 1394
P T K P P+ P P P G T+ P P P++ P AP + P T +
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT--SD 682
Query: 1395 VGGPGAPEGTPAGRARGGS------PAP-LPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
P P+ T + + PAP P TS + E +
Sbjct: 683 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 742
Query: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSA 1504
PE +A + + PG+P K + P++ + + +D T +A
Sbjct: 743 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 799
Score = 32.3 bits (72), Expect = 3.7
Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 1/75 (1%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
P P T P P PPP T +++ P + P + P P K
Sbjct: 697 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 756
Query: 1393 ENVGGPGAP-EGTPA 1406
+ PG P TPA
Sbjct: 757 NSPKEPGVPTTKTPA 771
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 127 bits (319), Expect = 8e-29
Identities = 136/550 (24%), Positives = 187/550 (34%), Gaps = 81/550 (14%)
Query: 568 TQSQPA-PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626
T+S P P PA TT + P A T + PA T ++AP +PAP
Sbjct: 293 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-------PAPTTTKSAPTTPKEPAPT 345
Query: 627 AP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
P PA +TP + A P+ PTP P TT +P+P P +P
Sbjct: 346 TPKKPAPTTP------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
TP + P + + P AP ++P+P TP
Sbjct: 400 TTP----------------KEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPT 432
Query: 745 LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP-SPHPTRPPSRP 803
AP + PAP A K P P+++ P +P P P PT P
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492
Query: 804 PSRPQ-----SVSRPPSEPPLHPCP--PPQAPPTLP-GIFVIQNQLGVPPPASNPAPTAP 855
P+ P+ + +P P P P P + PT P + + P PAPT P
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 856 GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQLQFPPSQ 914
P P+ P P PAP P ++ + + T+ + PAP TP + P
Sbjct: 553 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTT----------PFPALPQ--------- 955
P PT P P P P P+ TT P P P+
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671
Query: 956 --PKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP- 1010
P E P G AP P+ L P T+ + S + TP
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSG 1069
TAP+ PAP P P S + T K ++ P + +LS
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 789
Query: 1070 LKKPPTLQPS 1079
P L+ S
Sbjct: 790 EPTPKALENS 799
Score = 125 bits (315), Expect = 2e-28
Identities = 141/533 (26%), Positives = 184/533 (34%), Gaps = 74/533 (13%)
Query: 552 PALFQMPVSLAAGSLPTQ-SQPAPAGP---AATTVLQGVTLPPSAVAMLNTPDGLVQPAT 607
P + P S PT +PAP P A TT + P TP P
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----TP---TTPKE 373
Query: 608 PAAATGEAAPVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP- 664
PA T E AP +PAP AP PA +TP + A P+ P P P TTP
Sbjct: 374 PAPTTKEPAPTTPKEPAPTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIV 724
+P+P S P+ T +A T P + + + P P +
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-----PSPTTTKEPAPTTPKEPAPTTPKK 482
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA-PQIPAAAPLKGPGPSSSPSLPHQA 783
AP ++PAP TP AP + PAP P+ PA K P++ L
Sbjct: 483 PAPTTPKEPAPTTPKEP-------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535
Query: 784 PLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P +P P P PT P P+ P+ + E P P P A P P +
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTP-------KEP 587
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP--PEGPLP-----PAPHLP--PSSTSSAVASSSE 893
P PAPT P P P ++ P P+G P PAP P P+ A ++ E
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 647
Query: 894 TSSRL---PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
+S PAPT P P P PT P P P P T +
Sbjct: 648 PTSTTCDKPAPTT-------PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 951 PALPQPKALLERFHQVPSGIILQNKAGG-------------APAAPQTSTSLGPLTSPAA 997
P P PK L + P+ A AP P+ P T P
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760
Query: 998 SVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
+ VS + PT +P + + P EN +PT A
Sbjct: 761 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813
Score = 123 bits (308), Expect = 2e-27
Identities = 130/518 (25%), Positives = 171/518 (33%), Gaps = 67/518 (12%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD--GLVQPATPAAATGEAAPVLTVQPA 624
PT A P A T +G L TP P P T ++AP +PA
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 625 P----QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG 680
P AP P P ++P A P+ P P P TT + +P P
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348
Query: 681 QPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA 740
+P TP + P + + P + P P ++PAP TP
Sbjct: 349 KPAPTTP----------------KEPAPTTPKEPTPTTPK----EPAPTTKEPAPTTP-- 386
Query: 741 KGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
AP + PAP P+ PA K P P+++ P +P PT
Sbjct: 387 -----KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 800 PSRPPSRPQSVSRPPSEP----PLHPCP--PPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P+ +S P EP P P P + PT P + P PAPT
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-------KKPAPTTPKEPAPT 494
Query: 854 APGPPQP-------PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSD 905
P P P P P+ P P AP P T + + T+ PAP TP +
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 554
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
P P P PT P P P P T + P P P E
Sbjct: 555 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 614
Query: 966 VPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP--TAPSHAPAPAP 1021
P G AP P+ L P T+ + + TP TAP+ PAP
Sbjct: 615 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 674
Query: 1022 MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
P P PT + + A + P KP+
Sbjct: 675 TTPKEPAPTTP------KGTAPT-TLKEPAPTTPKKPA 705
Score = 120 bits (300), Expect = 1e-26
Identities = 178/722 (24%), Positives = 240/722 (33%), Gaps = 140/722 (19%)
Query: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG 375
PT T +P + ++P P P I TP +P P K TPK AP
Sbjct: 257 PTPTTPKEPAS------TTPKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPKEPAP-- 305
Query: 376 ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAA 435
T EP P PK P T K+P TTT +A
Sbjct: 306 ---TTTKEPA--PTTPKEPAPTT-------------------------TKEPAPTTTKSA 335
Query: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG 495
P P PA P PA P++ PA
Sbjct: 336 PTTPKE-------------------PAP---------TTPKKPAPTTPKE----PAPTTP 363
Query: 496 QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALF 555
+ P P T P AP A + AP +PA
Sbjct: 364 KEPTPTTPKEPAPTTKEPAPTTPKEPAP------TAPKKPAPTTP-KEPAPTTPKEPA-- 414
Query: 556 QMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEA 615
P + S T +PA P T T P+ + P +P+ T E
Sbjct: 415 --PTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS--PTTTKEP 467
Query: 616 APVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLAS 672
AP +PAP P PA +TP + A P+ P P P TTP +P+P +
Sbjct: 468 APTTPKEPAPTTPKKPAPTTP------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP---T 518
Query: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
+P++ P TPT T + L P++ + P P + P ++
Sbjct: 519 TPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTT-----PEELAPTTPEEPTPTTPEE 570
Query: 733 PAPATPVAKGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSP-H 790
PAP TP A AP++ PAP P+ PA K P P++ P G +P
Sbjct: 571 PAPTTPKA-------AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623
Query: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
L P PT P + P+ + EP C P AP T G + P P
Sbjct: 624 LKEPAPTTP--KKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEP 680
Query: 851 APTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
APT P P + P P L P++T +++S+ PAPT
Sbjct: 681 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK----PAPTT------- 729
Query: 911 PPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT-----TPFPALPQPKALLERFHQ 965
P P P PT P P P PPP T ++ T P P
Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789
Query: 966 VPSGIILQN--KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
P+ L+N K G P +T + P + A + + TP + AP
Sbjct: 790 EPTPKALENSPKEPGVPTT-KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 848
Query: 1024 AT 1025
AT
Sbjct: 849 AT 850
Score = 105 bits (263), Expect = 3e-22
Identities = 188/845 (22%), Positives = 263/845 (31%), Gaps = 143/845 (16%)
Query: 248 PTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVF 307
PTS++LAK P + + GP+ +P+ K TT+
Sbjct: 230 PTSKVLAKPTPKAE--TTTKGPALTTPKEPTPTTPKEPASTTPKE---PTPTTIKSAPTT 284
Query: 308 GGAGAA----SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKL 363
A SAPT P ++P PAP + P P K A P +
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT--KEPAPTTTKSAPTTPKEP 342
Query: 364 YQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423
TPK AP T EP P PK P T P A
Sbjct: 343 APTTPKKPAP-----TTPKEPA--PTTPKEPTPTT------------------PKEPAPT 377
Query: 424 FKQPPATTTGAAPPQP-PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQL 482
K+P TT P +P P A KP P + P PA
Sbjct: 378 TKEPAPTT----PKEPAPTAPKKPAPT----------------TPKEPAPTTPKEPAPTT 417
Query: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
++ S +AP T + P T P P +
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-- 473
Query: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA---GPAATTVLQGVTLPPSAVAMLNTP 599
AP +PA P + + T +PAP PA TT + P A TP
Sbjct: 474 EPAPTTPKKPA----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP-TTP 528
Query: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659
L P TP + AP +PAP P ++ P P + P TP+AAAP
Sbjct: 529 KKLT-PTTPE----KLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAP- 581
Query: 660 QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
T +P+P P +P TP + P + +G
Sbjct: 582 -NTPKEPAPTTPKEPAPTTPKEPAPTTP----------------KETAPTTPKG------ 618
Query: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
+AP ++PAP TP PAP+ A K P ++
Sbjct: 619 -----TAPTTLKEPAPTTP-----------------KKPAPKELAPTTTKEPTSTTCDKP 656
Query: 780 PHQAPLGDSPHLP-SPHPTRPPSRPPSRPQ-----SVSRPPSEPPLHPCPPPQAPPTLPG 833
P G +P P P PT P P+ P+ ++ P P P P AP T G
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 834 IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS--SAVASS 891
+ P APT P P P P+ P P P PP +TS S ++
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAP------TTPKKPAPTTPETPPPTTSEVSTPTTT 770
Query: 892 SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951
E ++ +P S +L P+ ++ P + PAA P T + TT
Sbjct: 771 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 830
Query: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
P + + K T + + T+ S P T
Sbjct: 831 LRTTP--------ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 882
Query: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
+ AP NK + P + ++ P + K + K
Sbjct: 883 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 942
Query: 1072 KPPTL 1076
KP T+
Sbjct: 943 KPKTM 947
Score = 81.3 bits (199), Expect = 7e-15
Identities = 99/438 (22%), Positives = 142/438 (32%), Gaps = 70/438 (15%)
Query: 631 VSTPLPLGLQQPQAQQPPQAPT-----PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
V+TP Q + P+ T P+ + PP + T + + L + E V +
Sbjct: 140 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET-SLTVNKETTV--ETKET 196
Query: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
T T T + + Q + P S +++ P TP A+
Sbjct: 197 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---------TPKAETTTK 247
Query: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS 805
GP + P+ PA+ K P P++ S P +P P+P T+ P
Sbjct: 248 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP------TTPKEPAPTTTKSAPTTPK 301
Query: 806 RPQ--SVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLR 863
P + P P P P P P + APT P P P
Sbjct: 302 EPAPTTTKEPAPTTPKEPAPTTTKEPA--------------PTTTKSAPTTPKEPAPTT- 346
Query: 864 PQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
P+ P P PAP P T T+ + PAPT + P P P
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTP--------TTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 924 PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
PT P P P P P T + + P P P +AP
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT--------------------TKSAP 438
Query: 984 QTSTSLGPLTSPAASVLVSGQAPSGT-PTAPSHAPAPAPMAATGLPPLLPAENKAFASNL 1042
T+ P T+ +A +P+ T AP+ PAP P P E
Sbjct: 439 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 498
Query: 1043 PT-LNVAKAASSGPGKPS 1059
P K A + P +P+
Sbjct: 499 PAPTTTKKPAPTTPKEPA 516
Score = 66.6 bits (161), Expect = 2e-10
Identities = 153/721 (21%), Positives = 214/721 (29%), Gaps = 154/721 (21%)
Query: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPA 374
APT P ++P PAP T +P P P P
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465
Query: 375 GATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA 434
T EP P PK P T PAP K+P TTT
Sbjct: 466 EPAPTTPKEPA--PTTPKKPAPTT-------------PKEPAPTTP----KEPAPTTTKK 506
Query: 435 APPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVG 494
P P +P + P + L P P +L PA
Sbjct: 507 PAPTTP---KEPAPT-----------TPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTT 551
Query: 495 GQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
+ LA P P T P + +AAP +PA
Sbjct: 552 PEELAPTTPE-------EPTPTTPEEPAPTT---------------PKAAAPNTPKEPA- 588
Query: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
P + + T +PAP P T TP G T E
Sbjct: 589 ---PTTPKEPAPTTPKEPAPTTPKETAP--------------TTPKG-----TAPTTLKE 626
Query: 615 AAPVLTVQPAPQ--APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLA 671
AP +PAP+ AP P +P A P+ P P TTP +P+P
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTP 685
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
L +P TP P + P + +GP + AP +
Sbjct: 686 KGTAPTTLKEPAPTTPKK-----------PAPKELAPTTTKGPTSTTSDK---PAPTTPK 731
Query: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+ AP TP P P A P P + + P + P+ H++P +P L
Sbjct: 732 ETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP----PPA 847
S PT P+++ P EP GVP P A
Sbjct: 788 -SAEPT---------PKALENSPKEP------------------------GVPTTKTPAA 813
Query: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ 907
+ P T + R PE ++T++ + S+ ++ T + Q
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873
Query: 908 LQFPPSQGPHKSPTPPP----------TLHLVPEPAAPPPPPPR-TFQMVTTPFPALPQP 956
P K+ T P T ++ +P P R T TTP P P
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 933
Query: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA 1016
+ P + K P P+ TS P +P + + +A T T P+
Sbjct: 934 APKKPTSTKKPKTMPRVRKPKTTP-TPRKMTSTMPELNPTSRI---AEAMLQTTTRPNQT 989
Query: 1017 P 1017
P
Sbjct: 990 P 990
Score = 52.8 bits (125), Expect = 3e-06
Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 43/373 (11%)
Query: 1182 EEKTTLALDKQ-LAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP- 1239
+EKTT A + Q + K + +S+ L P + + P P +P
Sbjct: 208 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 267
Query: 1240 --PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
P PT I+ +P+ A ++ S+ ++ + E P + P
Sbjct: 268 TTPKEPTPTTIK-----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 322
Query: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPT- 1356
T E +K T +P P PA EP P P P PT
Sbjct: 323 TTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 1357 -GQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPA 1415
+ T P P P+ AP P+ P T +E AP TP A +
Sbjct: 371 PKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKE-----PAPT-TPKEPAPTTTKE 420
Query: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR 1475
P P E + E K P P + T +P P P
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
K +P +P++ T + A + + PAP+ P + TP
Sbjct: 481 KKPAP---------TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531
Query: 1536 PPLHRPEAYPPSS 1548
P PE P++
Sbjct: 532 TPT-TPEKLAPTT 543
Score = 48.1 bits (113), Expect = 6e-05
Identities = 56/222 (25%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPER-KPLGTA 1379
NT +P P PA EP P P P P G T+ P P P++ P A
Sbjct: 582 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P + P T + P P+GT AP K T+
Sbjct: 642 PTTTKEPTSTTC--DKPAPTTPKGT----------APTTPKEPAPTT------------- 676
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWE--APGLP--PAKRRKSESPDVDQASFSSDSPQDD 1495
P EPA + +GT + AP P PA + + + S +SD P
Sbjct: 677 --------PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728
Query: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
T E + + PAP+ P + TP +PPP
Sbjct: 729 TPKETAPTT-----------PKEPAPTTPKKPAPTTPETPPP 759
Score = 47.0 bits (110), Expect = 1e-04
Identities = 55/223 (24%), Positives = 79/223 (35%), Gaps = 34/223 (15%)
Query: 872 PLPPAPHLPPSSTSSAVAS---SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
P+ P P LPP+S +S S + ET+ T ++ Q + G K+ + T +
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS---TDGKEKTTSAKETQSI 220
Query: 929 VPEPA----------APPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGG 978
A A P P T TT PAL PK P+ + A
Sbjct: 221 EKTSAKDLAPTSKVLAKPTPKAET----TTKGPALTTPKE--------PTPTTPKEPAST 268
Query: 979 APAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAF 1038
P P +T T+P AP+ T +AP+ PAP P P E
Sbjct: 269 TPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 322
Query: 1039 ASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P K+A + P +P+ + K P KE
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 365
Score = 44.7 bits (104), Expect = 7e-04
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 24/226 (10%)
Query: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379
K T +P P PA EP P P P PT + PA K +A
Sbjct: 396 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK---SA 452
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P P+ P T +E AP TP A P P E +E A
Sbjct: 453 PTTPKEPSPTTTKE-----PAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-- 504
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTE 1499
++ P EPA + + T AP P K+ +P+ + +P+ T
Sbjct: 505 -KKPAPTTPKEPAPTTPKET------APTTP--KKLTPTTPE----KLAPTTPEKPAPTT 551
Query: 1500 HLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYP 1545
+ A + PAP+ P AA+ TP P P E P
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/210 (21%), Positives = 71/210 (33%), Gaps = 10/210 (4%)
Query: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT------PPPTLHLVPEPAAP 935
++++ S +TS++ APT P ++ K P P PT P P
Sbjct: 211 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 270
Query: 936 PPPPPRTFQMV-TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
P P T + TTP P + P+ + A P P +T+ P +
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330
Query: 995 PAASVLVSGQAPSGTPT---APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAA 1051
S + + P+ T AP+ PAP P P E + A
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390
Query: 1052 SSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P KP+ + K P +KE
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Score = 42.4 bits (98), Expect = 0.004
Identities = 70/327 (21%), Positives = 103/327 (31%), Gaps = 46/327 (14%)
Query: 1231 APGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMP 1290
AP A +P P P + +P+ A ++ S ++ + + P
Sbjct: 390 APTAPKKPAPTTPKE---------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440
Query: 1291 SRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPP 1350
++ P T A + K + T +P P PA EP P P
Sbjct: 441 TKEPAPTTTKSAPTTP----KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 496
Query: 1351 PPPPPTGQMNGTVDHPPPAAPERK----PLGTAPHCPRLPLRKTYRENVGGPGAPEG--- 1403
P PT T P P P+ P TAP P+ L T E + P PE
Sbjct: 497 KEPAPT-----TTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLA-PTTPEKPAP 549
Query: 1404 -TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
TP A P P +E + A P EPA + + +P
Sbjct: 550 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-----------NTPKEPAPTTPK---EP 595
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRT---- 1518
P P K +P + + + + T + + + P T
Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655
Query: 1519 PAPSYPHAASAGTPASPPPLHRPEAYP 1545
PAP+ P + TP P P E P
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAP 682
Score = 32.7 bits (73), Expect = 2.8
Identities = 39/177 (22%), Positives = 61/177 (34%), Gaps = 11/177 (6%)
Query: 1337 PATLKVAEPP-PRPPPPPPPTGQMNGTVDHPPPAAPER-KPLGTAPHCPRLPLRKTYREN 1394
P T K P P+ P P P G T+ P P P++ P AP + P T +
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT--SD 723
Query: 1395 VGGPGAPEGTPAGRARGGS------PAP-LPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
P P+ T + + PAP P TS + E +
Sbjct: 724 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783
Query: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSA 1504
PE +A + + PG+P K + P++ + + +D T +A
Sbjct: 784 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 840
Score = 32.3 bits (72), Expect = 3.7
Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 1/75 (1%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
P P T P P PPP T +++ P + P + P P K
Sbjct: 738 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 797
Query: 1393 ENVGGPGAP-EGTPA 1406
+ PG P TPA
Sbjct: 798 NSPKEPGVPTTKTPA 812
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 127 bits (319), Expect = 8e-29
Identities = 136/550 (24%), Positives = 187/550 (34%), Gaps = 81/550 (14%)
Query: 568 TQSQPA-PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626
T+S P P PA TT + P A T + PA T ++AP +PAP
Sbjct: 345 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-------PAPTTTKSAPTTPKEPAPT 397
Query: 627 AP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
P PA +TP + A P+ PTP P TT +P+P P +P
Sbjct: 398 TPKKPAPTTP------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
TP + P + + P AP ++P+P TP
Sbjct: 452 TTP----------------KEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPT 484
Query: 745 LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP-SPHPTRPPSRP 803
AP + PAP A K P P+++ P +P P P PT P
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544
Query: 804 PSRPQ-----SVSRPPSEPPLHPCP--PPQAPPTLP-GIFVIQNQLGVPPPASNPAPTAP 855
P+ P+ + +P P P P P + PT P + + P PAPT P
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 604
Query: 856 GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQLQFPPSQ 914
P P+ P P PAP P ++ + + T+ + PAP TP + P
Sbjct: 605 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTT----------PFPALPQ--------- 955
P PT P P P P P+ TT P P P+
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723
Query: 956 --PKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP- 1010
P E P G AP P+ L P T+ + S + TP
Sbjct: 724 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSG 1069
TAP+ PAP P P S + T K ++ P + +LS
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 841
Query: 1070 LKKPPTLQPS 1079
P L+ S
Sbjct: 842 EPTPKALENS 851
Score = 125 bits (315), Expect = 2e-28
Identities = 141/533 (26%), Positives = 184/533 (34%), Gaps = 74/533 (13%)
Query: 552 PALFQMPVSLAAGSLPTQ-SQPAPAGP---AATTVLQGVTLPPSAVAMLNTPDGLVQPAT 607
P + P S PT +PAP P A TT + P TP P
Sbjct: 373 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----TP---TTPKE 425
Query: 608 PAAATGEAAPVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP- 664
PA T E AP +PAP AP PA +TP + A P+ P P P TTP
Sbjct: 426 PAPTTKEPAPTTPKEPAPTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIV 724
+P+P S P+ T +A T P + + + P P +
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-----PSPTTTKEPAPTTPKEPAPTTPKK 534
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA-PQIPAAAPLKGPGPSSSPSLPHQA 783
AP ++PAP TP AP + PAP P+ PA K P++ L
Sbjct: 535 PAPTTPKEPAPTTPKEP-------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 784 PLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P +P P P PT P P+ P+ + E P P P A P P +
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTP-------KEP 639
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP--PEGPLP-----PAPHLP--PSSTSSAVASSSE 893
P PAPT P P P ++ P P+G P PAP P P+ A ++ E
Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 699
Query: 894 TSSRL---PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
+S PAPT P P P PT P P P P T +
Sbjct: 700 PTSTTCDKPAPTT-------PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 951 PALPQPKALLERFHQVPSGIILQNKAGG-------------APAAPQTSTSLGPLTSPAA 997
P P PK L + P+ A AP P+ P T P
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 812
Query: 998 SVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
+ VS + PT +P + + P EN +PT A
Sbjct: 813 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Score = 123 bits (308), Expect = 2e-27
Identities = 130/518 (25%), Positives = 171/518 (33%), Gaps = 67/518 (12%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD--GLVQPATPAAATGEAAPVLTVQPA 624
PT A P A T +G L TP P P T ++AP +PA
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 625 P----QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG 680
P AP P P ++P A P+ P P P TT + +P P
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400
Query: 681 QPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA 740
+P TP + P + + P + P P ++PAP TP
Sbjct: 401 KPAPTTP----------------KEPAPTTPKEPTPTTPK----EPAPTTKEPAPTTP-- 438
Query: 741 KGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
AP + PAP P+ PA K P P+++ P +P PT
Sbjct: 439 -----KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 800 PSRPPSRPQSVSRPPSEP----PLHPCP--PPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P+ +S P EP P P P + PT P + P PAPT
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-------KKPAPTTPKEPAPT 546
Query: 854 APGPPQP-------PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSD 905
P P P P P+ P P AP P T + + T+ PAP TP +
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 606
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
P P P PT P P P P T + P P P E
Sbjct: 607 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 666
Query: 966 VPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP--TAPSHAPAPAP 1021
P G AP P+ L P T+ + + TP TAP+ PAP
Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726
Query: 1022 MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
P P PT + + A + P KP+
Sbjct: 727 TTPKEPAPTTP------KGTAPT-TLKEPAPTTPKKPA 757
Score = 120 bits (300), Expect = 1e-26
Identities = 178/722 (24%), Positives = 240/722 (33%), Gaps = 140/722 (19%)
Query: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG 375
PT T +P + ++P P P I TP +P P K TPK AP
Sbjct: 309 PTPTTPKEPAS------TTPKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPKEPAP-- 357
Query: 376 ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAA 435
T EP P PK P T K+P TTT +A
Sbjct: 358 ---TTTKEPA--PTTPKEPAPTT-------------------------TKEPAPTTTKSA 387
Query: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG 495
P P PA P PA P++ PA
Sbjct: 388 PTTPKE-------------------PAP---------TTPKKPAPTTPKE----PAPTTP 415
Query: 496 QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALF 555
+ P P T P AP A + AP +PA
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKEPAP------TAPKKPAPTTP-KEPAPTTPKEPA-- 466
Query: 556 QMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEA 615
P + S T +PA P T T P+ + P +P+ T E
Sbjct: 467 --PTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS--PTTTKEP 519
Query: 616 APVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLAS 672
AP +PAP P PA +TP + A P+ P P P TTP +P+P +
Sbjct: 520 APTTPKEPAPTTPKKPAPTTP------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP---T 570
Query: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
+P++ P TPT T + L P++ + P P + P ++
Sbjct: 571 TPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTT-----PEELAPTTPEEPTPTTPEE 622
Query: 733 PAPATPVAKGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSP-H 790
PAP TP A AP++ PAP P+ PA K P P++ P G +P
Sbjct: 623 PAPTTPKA-------AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675
Query: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
L P PT P + P+ + EP C P AP T G + P P
Sbjct: 676 LKEPAPTTP--KKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEP 732
Query: 851 APTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
APT P P + P P L P++T +++S+ PAPT
Sbjct: 733 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK----PAPTT------- 781
Query: 911 PPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT-----TPFPALPQPKALLERFHQ 965
P P P PT P P P PPP T ++ T P P
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 966 VPSGIILQN--KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
P+ L+N K G P +T + P + A + + TP + AP
Sbjct: 842 EPTPKALENSPKEPGVPTT-KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 900
Query: 1024 AT 1025
AT
Sbjct: 901 AT 902
Score = 105 bits (263), Expect = 3e-22
Identities = 188/845 (22%), Positives = 263/845 (31%), Gaps = 143/845 (16%)
Query: 248 PTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVF 307
PTS++LAK P + + GP+ +P+ K TT+
Sbjct: 282 PTSKVLAKPTPKAE--TTTKGPALTTPKEPTPTTPKEPASTTPKE---PTPTTIKSAPTT 336
Query: 308 GGAGAA----SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKL 363
A SAPT P ++P PAP + P P K A P +
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT--KEPAPTTTKSAPTTPKEP 394
Query: 364 YQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423
TPK AP T EP P PK P T P A
Sbjct: 395 APTTPKKPAP-----TTPKEPA--PTTPKEPTPTT------------------PKEPAPT 429
Query: 424 FKQPPATTTGAAPPQP-PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQL 482
K+P TT P +P P A KP P + P PA
Sbjct: 430 TKEPAPTT----PKEPAPTAPKKPAPT----------------TPKEPAPTTPKEPAPTT 469
Query: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
++ S +AP T + P T P P +
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-- 525
Query: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA---GPAATTVLQGVTLPPSAVAMLNTP 599
AP +PA P + + T +PAP PA TT + P A TP
Sbjct: 526 EPAPTTPKKPA----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP-TTP 580
Query: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659
L P TP + AP +PAP P ++ P P + P TP+AAAP
Sbjct: 581 KKLT-PTTPE----KLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAP- 633
Query: 660 QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
T +P+P P +P TP + P + +G
Sbjct: 634 -NTPKEPAPTTPKEPAPTTPKEPAPTTP----------------KETAPTTPKG------ 670
Query: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
+AP ++PAP TP PAP+ A K P ++
Sbjct: 671 -----TAPTTLKEPAPTTP-----------------KKPAPKELAPTTTKEPTSTTCDKP 708
Query: 780 PHQAPLGDSPHLP-SPHPTRPPSRPPSRPQ-----SVSRPPSEPPLHPCPPPQAPPTLPG 833
P G +P P P PT P P+ P+ ++ P P P P AP T G
Sbjct: 709 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 768
Query: 834 IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS--SAVASS 891
+ P APT P P P P+ P P P PP +TS S ++
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAP------TTPKKPAPTTPETPPPTTSEVSTPTTT 822
Query: 892 SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951
E ++ +P S +L P+ ++ P + PAA P T + TT
Sbjct: 823 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 882
Query: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
P + + K T + + T+ S P T
Sbjct: 883 LRTTP--------ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 934
Query: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
+ AP NK + P + ++ P + K + K
Sbjct: 935 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 994
Query: 1072 KPPTL 1076
KP T+
Sbjct: 995 KPKTM 999
Score = 81.3 bits (199), Expect = 7e-15
Identities = 99/438 (22%), Positives = 142/438 (32%), Gaps = 70/438 (15%)
Query: 631 VSTPLPLGLQQPQAQQPPQAPT-----PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
V+TP Q + P+ T P+ + PP + T + + L + E V +
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET-SLTVNKETTV--ETKET 248
Query: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
T T T + + Q + P S +++ P TP A+
Sbjct: 249 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---------TPKAETTTK 299
Query: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS 805
GP + P+ PA+ K P P++ S P +P P+P T+ P
Sbjct: 300 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP------TTPKEPAPTTTKSAPTTPK 353
Query: 806 RPQ--SVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLR 863
P + P P P P P P + APT P P P
Sbjct: 354 EPAPTTTKEPAPTTPKEPAPTTTKEPA--------------PTTTKSAPTTPKEPAPTT- 398
Query: 864 PQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
P+ P P PAP P T T+ + PAPT + P P P
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTP--------TTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 924 PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
PT P P P P P T + + P P P +AP
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT--------------------TKSAP 490
Query: 984 QTSTSLGPLTSPAASVLVSGQAPSGT-PTAPSHAPAPAPMAATGLPPLLPAENKAFASNL 1042
T+ P T+ +A +P+ T AP+ PAP P P E
Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 550
Query: 1043 PT-LNVAKAASSGPGKPS 1059
P K A + P +P+
Sbjct: 551 PAPTTTKKPAPTTPKEPA 568
Score = 66.6 bits (161), Expect = 2e-10
Identities = 153/721 (21%), Positives = 214/721 (29%), Gaps = 154/721 (21%)
Query: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPA 374
APT P ++P PAP T +P P P P
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517
Query: 375 GATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA 434
T EP P PK P T PAP K+P TTT
Sbjct: 518 EPAPTTPKEPA--PTTPKKPAPTT-------------PKEPAPTTP----KEPAPTTTKK 558
Query: 435 APPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVG 494
P P +P + P + L P P +L PA
Sbjct: 559 PAPTTP---KEPAPT-----------TPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTT 603
Query: 495 GQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
+ LA P P T P + +AAP +PA
Sbjct: 604 PEELAPTTPE-------EPTPTTPEEPAPTT---------------PKAAAPNTPKEPA- 640
Query: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
P + + T +PAP P T TP G T E
Sbjct: 641 ---PTTPKEPAPTTPKEPAPTTPKETAP--------------TTPKG-----TAPTTLKE 678
Query: 615 AAPVLTVQPAPQ--APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLA 671
AP +PAP+ AP P +P A P+ P P TTP +P+P
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTP 737
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
L +P TP P + P + +GP + AP +
Sbjct: 738 KGTAPTTLKEPAPTTPKK-----------PAPKELAPTTTKGPTSTTSDK---PAPTTPK 783
Query: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+ AP TP P P A P P + + P + P+ H++P +P L
Sbjct: 784 ETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP----PPA 847
S PT P+++ P EP GVP P A
Sbjct: 840 -SAEPT---------PKALENSPKEP------------------------GVPTTKTPAA 865
Query: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ 907
+ P T + R PE ++T++ + S+ ++ T + Q
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925
Query: 908 LQFPPSQGPHKSPTPPP----------TLHLVPEPAAPPPPPPR-TFQMVTTPFPALPQP 956
P K+ T P T ++ +P P R T TTP P P
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 985
Query: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA 1016
+ P + K P P+ TS P +P + + +A T T P+
Sbjct: 986 APKKPTSTKKPKTMPRVRKPKTTP-TPRKMTSTMPELNPTSRI---AEAMLQTTTRPNQT 1041
Query: 1017 P 1017
P
Sbjct: 1042 P 1042
Score = 52.8 bits (125), Expect = 3e-06
Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 43/373 (11%)
Query: 1182 EEKTTLALDKQ-LAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP- 1239
+EKTT A + Q + K + +S+ L P + + P P +P
Sbjct: 260 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 319
Query: 1240 --PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
P PT I+ +P+ A ++ S+ ++ + E P + P
Sbjct: 320 TTPKEPTPTTIK-----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 374
Query: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPT- 1356
T E +K T +P P PA EP P P P PT
Sbjct: 375 TTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 1357 -GQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPA 1415
+ T P P P+ AP P+ P T +E AP TP A +
Sbjct: 423 PKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKE-----PAPT-TPKEPAPTTTKE 472
Query: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR 1475
P P E + E K P P + T +P P P
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 532
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
K +P +P++ T + A + + PAP+ P + TP
Sbjct: 533 KKPAP---------TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583
Query: 1536 PPLHRPEAYPPSS 1548
P PE P++
Sbjct: 584 TPT-TPEKLAPTT 595
Score = 48.1 bits (113), Expect = 6e-05
Identities = 56/222 (25%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPER-KPLGTA 1379
NT +P P PA EP P P P P G T+ P P P++ P A
Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P + P T + P P+GT AP K T+
Sbjct: 694 PTTTKEPTSTTC--DKPAPTTPKGT----------APTTPKEPAPTT------------- 728
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWE--APGLP--PAKRRKSESPDVDQASFSSDSPQDD 1495
P EPA + +GT + AP P PA + + + S +SD P
Sbjct: 729 --------PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780
Query: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
T E + + PAP+ P + TP +PPP
Sbjct: 781 TPKETAPTT-----------PKEPAPTTPKKPAPTTPETPPP 811
Score = 47.0 bits (110), Expect = 1e-04
Identities = 55/223 (24%), Positives = 79/223 (35%), Gaps = 34/223 (15%)
Query: 872 PLPPAPHLPPSSTSSAVAS---SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
P+ P P LPP+S +S S + ET+ T ++ Q + G K+ + T +
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS---TDGKEKTTSAKETQSI 272
Query: 929 VPEPA----------APPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGG 978
A A P P T TT PAL PK P+ + A
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAET----TTKGPALTTPKE--------PTPTTPKEPAST 320
Query: 979 APAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAF 1038
P P +T T+P AP+ T +AP+ PAP P P E
Sbjct: 321 TPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 374
Query: 1039 ASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P K+A + P +P+ + K P KE
Sbjct: 375 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417
Score = 44.7 bits (104), Expect = 7e-04
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 24/226 (10%)
Query: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379
K T +P P PA EP P P P PT + PA K +A
Sbjct: 448 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK---SA 504
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P P+ P T +E AP TP A P P E +E A
Sbjct: 505 PTTPKEPSPTTTKE-----PAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-- 556
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTE 1499
++ P EPA + + T AP P K+ +P+ + +P+ T
Sbjct: 557 -KKPAPTTPKEPAPTTPKET------APTTP--KKLTPTTPE----KLAPTTPEKPAPTT 603
Query: 1500 HLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYP 1545
+ A + PAP+ P AA+ TP P P E P
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/210 (21%), Positives = 71/210 (33%), Gaps = 10/210 (4%)
Query: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT------PPPTLHLVPEPAAP 935
++++ S +TS++ APT P ++ K P P PT P P
Sbjct: 263 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 322
Query: 936 PPPPPRTFQMV-TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
P P T + TTP P + P+ + A P P +T+ P +
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382
Query: 995 PAASVLVSGQAPSGTPT---APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAA 1051
S + + P+ T AP+ PAP P P E + A
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442
Query: 1052 SSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P KP+ + K P +KE
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472
Score = 42.4 bits (98), Expect = 0.004
Identities = 70/327 (21%), Positives = 103/327 (31%), Gaps = 46/327 (14%)
Query: 1231 APGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMP 1290
AP A +P P P + +P+ A ++ S ++ + + P
Sbjct: 442 APTAPKKPAPTTPKE---------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492
Query: 1291 SRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPP 1350
++ P T A + K + T +P P PA EP P P
Sbjct: 493 TKEPAPTTTKSAPTTP----KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 548
Query: 1351 PPPPPTGQMNGTVDHPPPAAPERK----PLGTAPHCPRLPLRKTYRENVGGPGAPEG--- 1403
P PT T P P P+ P TAP P+ L T E + P PE
Sbjct: 549 KEPAPT-----TTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLA-PTTPEKPAP 601
Query: 1404 -TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
TP A P P +E + A P EPA + + +P
Sbjct: 602 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-----------NTPKEPAPTTPK---EP 647
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRT---- 1518
P P K +P + + + + T + + + P T
Sbjct: 648 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707
Query: 1519 PAPSYPHAASAGTPASPPPLHRPEAYP 1545
PAP+ P + TP P P E P
Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAP 734
Score = 32.7 bits (73), Expect = 2.8
Identities = 39/177 (22%), Positives = 61/177 (34%), Gaps = 11/177 (6%)
Query: 1337 PATLKVAEPP-PRPPPPPPPTGQMNGTVDHPPPAAPER-KPLGTAPHCPRLPLRKTYREN 1394
P T K P P+ P P P G T+ P P P++ P AP + P T +
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT--SD 775
Query: 1395 VGGPGAPEGTPAGRARGGS------PAP-LPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
P P+ T + + PAP P TS + E +
Sbjct: 776 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 835
Query: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSA 1504
PE +A + + PG+P K + P++ + + +D T +A
Sbjct: 836 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 892
Score = 32.3 bits (72), Expect = 3.7
Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 1/75 (1%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
P P T P P PPP T +++ P + P + P P K
Sbjct: 790 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 849
Query: 1393 ENVGGPGAP-EGTPA 1406
+ PG P TPA
Sbjct: 850 NSPKEPGVPTTKTPA 864
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 127 bits (319), Expect = 8e-29
Identities = 136/550 (24%), Positives = 187/550 (34%), Gaps = 81/550 (14%)
Query: 568 TQSQPA-PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626
T+S P P PA TT + P A T + PA T ++AP +PAP
Sbjct: 386 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-------PAPTTTKSAPTTPKEPAPT 438
Query: 627 AP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
P PA +TP + A P+ PTP P TT +P+P P +P
Sbjct: 439 TPKKPAPTTP------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
TP + P + + P AP ++P+P TP
Sbjct: 493 TTP----------------KEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPT 525
Query: 745 LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP-SPHPTRPPSRP 803
AP + PAP A K P P+++ P +P P P PT P
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585
Query: 804 PSRPQ-----SVSRPPSEPPLHPCP--PPQAPPTLP-GIFVIQNQLGVPPPASNPAPTAP 855
P+ P+ + +P P P P P + PT P + + P PAPT P
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 645
Query: 856 GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQLQFPPSQ 914
P P+ P P PAP P ++ + + T+ + PAP TP + P
Sbjct: 646 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTT----------PFPALPQ--------- 955
P PT P P P P P+ TT P P P+
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764
Query: 956 --PKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP- 1010
P E P G AP P+ L P T+ + S + TP
Sbjct: 765 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824
Query: 1011 -TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSG 1069
TAP+ PAP P P S + T K ++ P + +LS
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 882
Query: 1070 LKKPPTLQPS 1079
P L+ S
Sbjct: 883 EPTPKALENS 892
Score = 125 bits (315), Expect = 2e-28
Identities = 141/533 (26%), Positives = 184/533 (34%), Gaps = 74/533 (13%)
Query: 552 PALFQMPVSLAAGSLPTQ-SQPAPAGP---AATTVLQGVTLPPSAVAMLNTPDGLVQPAT 607
P + P S PT +PAP P A TT + P TP P
Sbjct: 414 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----TP---TTPKE 466
Query: 608 PAAATGEAAPVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP- 664
PA T E AP +PAP AP PA +TP + A P+ P P P TTP
Sbjct: 467 PAPTTKEPAPTTPKEPAPTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIV 724
+P+P S P+ T +A T P + + + P P +
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-----PSPTTTKEPAPTTPKEPAPTTPKK 575
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA-PQIPAAAPLKGPGPSSSPSLPHQA 783
AP ++PAP TP AP + PAP P+ PA K P++ L
Sbjct: 576 PAPTTPKEPAPTTPKEP-------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 784 PLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P +P P P PT P P+ P+ + E P P P A P P +
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTP-------KEP 680
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP--PEGPLP-----PAPHLP--PSSTSSAVASSSE 893
P PAPT P P P ++ P P+G P PAP P P+ A ++ E
Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 740
Query: 894 TSSRL---PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
+S PAPT P P P PT P P P P T +
Sbjct: 741 PTSTTCDKPAPTT-------PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 951 PALPQPKALLERFHQVPSGIILQNKAGG-------------APAAPQTSTSLGPLTSPAA 997
P P PK L + P+ A AP P+ P T P
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 853
Query: 998 SVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
+ VS + PT +P + + P EN +PT A
Sbjct: 854 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Score = 123 bits (308), Expect = 2e-27
Identities = 130/518 (25%), Positives = 171/518 (33%), Gaps = 67/518 (12%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD--GLVQPATPAAATGEAAPVLTVQPA 624
PT A P A T +G L TP P P T ++AP +PA
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 625 P----QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG 680
P AP P P ++P A P+ P P P TT + +P P
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441
Query: 681 QPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA 740
+P TP + P + + P + P P ++PAP TP
Sbjct: 442 KPAPTTP----------------KEPAPTTPKEPTPTTPK----EPAPTTKEPAPTTP-- 479
Query: 741 KGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
AP + PAP P+ PA K P P+++ P +P PT
Sbjct: 480 -----KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 800 PSRPPSRPQSVSRPPSEP----PLHPCP--PPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P+ +S P EP P P P + PT P + P PAPT
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-------KKPAPTTPKEPAPT 587
Query: 854 APGPPQP-------PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSD 905
P P P P P+ P P AP P T + + T+ PAP TP +
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 647
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
P P P PT P P P P T + P P P E
Sbjct: 648 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 707
Query: 966 VPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGTP--TAPSHAPAPAP 1021
P G AP P+ L P T+ + + TP TAP+ PAP
Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767
Query: 1022 MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
P P PT + + A + P KP+
Sbjct: 768 TTPKEPAPTTP------KGTAPT-TLKEPAPTTPKKPA 798
Score = 120 bits (300), Expect = 1e-26
Identities = 178/722 (24%), Positives = 240/722 (33%), Gaps = 140/722 (19%)
Query: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG 375
PT T +P + ++P P P I TP +P P K TPK AP
Sbjct: 350 PTPTTPKEPAS------TTPKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPKEPAP-- 398
Query: 376 ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAA 435
T EP P PK P T K+P TTT +A
Sbjct: 399 ---TTTKEPA--PTTPKEPAPTT-------------------------TKEPAPTTTKSA 428
Query: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG 495
P P PA P PA P++ PA
Sbjct: 429 PTTPKE-------------------PAP---------TTPKKPAPTTPKE----PAPTTP 456
Query: 496 QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALF 555
+ P P T P AP A + AP +PA
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKEPAP------TAPKKPAPTTP-KEPAPTTPKEPA-- 507
Query: 556 QMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEA 615
P + S T +PA P T T P+ + P +P+ T E
Sbjct: 508 --PTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS--PTTTKEP 560
Query: 616 APVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLAS 672
AP +PAP P PA +TP + A P+ P P P TTP +P+P +
Sbjct: 561 APTTPKEPAPTTPKKPAPTTP------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP---T 611
Query: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
+P++ P TPT T + L P++ + P P + P ++
Sbjct: 612 TPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTT-----PEELAPTTPEEPTPTTPEE 663
Query: 733 PAPATPVAKGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSP-H 790
PAP TP A AP++ PAP P+ PA K P P++ P G +P
Sbjct: 664 PAPTTPKA-------AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 716
Query: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
L P PT P + P+ + EP C P AP T G + P P
Sbjct: 717 LKEPAPTTP--KKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEP 773
Query: 851 APTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
APT P P + P P L P++T +++S+ PAPT
Sbjct: 774 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK----PAPTT------- 822
Query: 911 PPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT-----TPFPALPQPKALLERFHQ 965
P P P PT P P P PPP T ++ T P P
Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 966 VPSGIILQN--KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
P+ L+N K G P +T + P + A + + TP + AP
Sbjct: 883 EPTPKALENSPKEPGVPTT-KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 941
Query: 1024 AT 1025
AT
Sbjct: 942 AT 943
Score = 105 bits (263), Expect = 3e-22
Identities = 188/845 (22%), Positives = 263/845 (31%), Gaps = 143/845 (16%)
Query: 248 PTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVF 307
PTS++LAK P + + GP+ +P+ K TT+
Sbjct: 323 PTSKVLAKPTPKAE--TTTKGPALTTPKEPTPTTPKEPASTTPKE---PTPTTIKSAPTT 377
Query: 308 GGAGAA----SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKL 363
A SAPT P ++P PAP + P P K A P +
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT--KEPAPTTTKSAPTTPKEP 435
Query: 364 YQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423
TPK AP T EP P PK P T P A
Sbjct: 436 APTTPKKPAP-----TTPKEPA--PTTPKEPTPTT------------------PKEPAPT 470
Query: 424 FKQPPATTTGAAPPQP-PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQL 482
K+P TT P +P P A KP P + P PA
Sbjct: 471 TKEPAPTT----PKEPAPTAPKKPAPT----------------TPKEPAPTTPKEPAPTT 510
Query: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
++ S +AP T + P T P P +
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-- 566
Query: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA---GPAATTVLQGVTLPPSAVAMLNTP 599
AP +PA P + + T +PAP PA TT + P A TP
Sbjct: 567 EPAPTTPKKPA----PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP-TTP 621
Query: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659
L P TP + AP +PAP P ++ P P + P TP+AAAP
Sbjct: 622 KKLT-PTTPE----KLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAP- 674
Query: 660 QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
T +P+P P +P TP + P + +G
Sbjct: 675 -NTPKEPAPTTPKEPAPTTPKEPAPTTP----------------KETAPTTPKG------ 711
Query: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
+AP ++PAP TP PAP+ A K P ++
Sbjct: 712 -----TAPTTLKEPAPTTP-----------------KKPAPKELAPTTTKEPTSTTCDKP 749
Query: 780 PHQAPLGDSPHLP-SPHPTRPPSRPPSRPQ-----SVSRPPSEPPLHPCPPPQAPPTLPG 833
P G +P P P PT P P+ P+ ++ P P P P AP T G
Sbjct: 750 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 809
Query: 834 IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS--SAVASS 891
+ P APT P P P P+ P P P PP +TS S ++
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAP------TTPKKPAPTTPETPPPTTSEVSTPTTT 863
Query: 892 SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951
E ++ +P S +L P+ ++ P + PAA P T + TT
Sbjct: 864 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 923
Query: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
P + + K T + + T+ S P T
Sbjct: 924 LRTTP--------ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 975
Query: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
+ AP NK + P + ++ P + K + K
Sbjct: 976 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 1035
Query: 1072 KPPTL 1076
KP T+
Sbjct: 1036 KPKTM 1040
Score = 81.3 bits (199), Expect = 7e-15
Identities = 99/438 (22%), Positives = 142/438 (32%), Gaps = 70/438 (15%)
Query: 631 VSTPLPLGLQQPQAQQPPQAPT-----PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
V+TP Q + P+ T P+ + PP + T + + L + E V +
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET-SLTVNKETTV--ETKET 289
Query: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
T T T + + Q + P S +++ P TP A+
Sbjct: 290 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---------TPKAETTTK 340
Query: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS 805
GP + P+ PA+ K P P++ S P +P P+P T+ P
Sbjct: 341 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP------TTPKEPAPTTTKSAPTTPK 394
Query: 806 RPQ--SVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLR 863
P + P P P P P P + APT P P P
Sbjct: 395 EPAPTTTKEPAPTTPKEPAPTTTKEPA--------------PTTTKSAPTTPKEPAPTT- 439
Query: 864 PQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
P+ P P PAP P T T+ + PAPT + P P P
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTP--------TTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 924 PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
PT P P P P P T + + P P P +AP
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT--------------------TKSAP 531
Query: 984 QTSTSLGPLTSPAASVLVSGQAPSGT-PTAPSHAPAPAPMAATGLPPLLPAENKAFASNL 1042
T+ P T+ +A +P+ T AP+ PAP P P E
Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 591
Query: 1043 PT-LNVAKAASSGPGKPS 1059
P K A + P +P+
Sbjct: 592 PAPTTTKKPAPTTPKEPA 609
Score = 66.6 bits (161), Expect = 2e-10
Identities = 153/721 (21%), Positives = 214/721 (29%), Gaps = 154/721 (21%)
Query: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPA 374
APT P ++P PAP T +P P P P
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558
Query: 375 GATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA 434
T EP P PK P T PAP K+P TTT
Sbjct: 559 EPAPTTPKEPA--PTTPKKPAPTT-------------PKEPAPTTP----KEPAPTTTKK 599
Query: 435 APPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVG 494
P P +P + P + L P P +L PA
Sbjct: 600 PAPTTP---KEPAPT-----------TPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTT 644
Query: 495 GQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
+ LA P P T P + +AAP +PA
Sbjct: 645 PEELAPTTPE-------EPTPTTPEEPAPTT---------------PKAAAPNTPKEPA- 681
Query: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
P + + T +PAP P T TP G T E
Sbjct: 682 ---PTTPKEPAPTTPKEPAPTTPKETAP--------------TTPKG-----TAPTTLKE 719
Query: 615 AAPVLTVQPAPQ--APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLA 671
AP +PAP+ AP P +P A P+ P P TTP +P+P
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTP 778
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
L +P TP P + P + +GP + AP +
Sbjct: 779 KGTAPTTLKEPAPTTPKK-----------PAPKELAPTTTKGPTSTTSDK---PAPTTPK 824
Query: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+ AP TP P P A P P + + P + P+ H++P +P L
Sbjct: 825 ETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP----PPA 847
S PT P+++ P EP GVP P A
Sbjct: 881 -SAEPT---------PKALENSPKEP------------------------GVPTTKTPAA 906
Query: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ 907
+ P T + R PE ++T++ + S+ ++ T + Q
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966
Query: 908 LQFPPSQGPHKSPTPPP----------TLHLVPEPAAPPPPPPR-TFQMVTTPFPALPQP 956
P K+ T P T ++ +P P R T TTP P P
Sbjct: 967 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 1026
Query: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA 1016
+ P + K P P+ TS P +P + + +A T T P+
Sbjct: 1027 APKKPTSTKKPKTMPRVRKPKTTP-TPRKMTSTMPELNPTSRI---AEAMLQTTTRPNQT 1082
Query: 1017 P 1017
P
Sbjct: 1083 P 1083
Score = 52.8 bits (125), Expect = 3e-06
Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 43/373 (11%)
Query: 1182 EEKTTLALDKQ-LAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP- 1239
+EKTT A + Q + K + +S+ L P + + P P +P
Sbjct: 301 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 360
Query: 1240 --PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
P PT I+ +P+ A ++ S+ ++ + E P + P
Sbjct: 361 TTPKEPTPTTIK-----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 415
Query: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPT- 1356
T E +K T +P P PA EP P P P PT
Sbjct: 416 TTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 1357 -GQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPA 1415
+ T P P P+ AP P+ P T +E AP TP A +
Sbjct: 464 PKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKE-----PAPT-TPKEPAPTTTKE 513
Query: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR 1475
P P E + E K P P + T +P P P
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 573
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
K +P +P++ T + A + + PAP+ P + TP
Sbjct: 574 KKPAP---------TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624
Query: 1536 PPLHRPEAYPPSS 1548
P PE P++
Sbjct: 625 TPT-TPEKLAPTT 636
Score = 48.1 bits (113), Expect = 6e-05
Identities = 56/222 (25%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPP---PPPPPTGQMNGTVDHPPPAAPER-KPLGTA 1379
NT +P P PA EP P P P P G T+ P P P++ P A
Sbjct: 675 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P + P T + P P+GT AP K T+
Sbjct: 735 PTTTKEPTSTTC--DKPAPTTPKGT----------APTTPKEPAPTT------------- 769
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWE--APGLP--PAKRRKSESPDVDQASFSSDSPQDD 1495
P EPA + +GT + AP P PA + + + S +SD P
Sbjct: 770 --------PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821
Query: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
T E + + PAP+ P + TP +PPP
Sbjct: 822 TPKETAPTT-----------PKEPAPTTPKKPAPTTPETPPP 852
Score = 47.0 bits (110), Expect = 1e-04
Identities = 55/223 (24%), Positives = 79/223 (35%), Gaps = 34/223 (15%)
Query: 872 PLPPAPHLPPSSTSSAVAS---SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
P+ P P LPP+S +S S + ET+ T ++ Q + G K+ + T +
Sbjct: 257 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS---TDGKEKTTSAKETQSI 313
Query: 929 VPEPA----------APPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGG 978
A A P P T TT PAL PK P+ + A
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAET----TTKGPALTTPKE--------PTPTTPKEPAST 361
Query: 979 APAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAF 1038
P P +T T+P AP+ T +AP+ PAP P P E
Sbjct: 362 TPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 415
Query: 1039 ASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P K+A + P +P+ + K P KE
Sbjct: 416 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458
Score = 44.7 bits (104), Expect = 7e-04
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 24/226 (10%)
Query: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379
K T +P P PA EP P P P PT + PA K +A
Sbjct: 489 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK---SA 545
Query: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
P P+ P T +E AP TP A P P E +E A
Sbjct: 546 PTTPKEPSPTTTKE-----PAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-- 597
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTE 1499
++ P EPA + + T AP P K+ +P+ + +P+ T
Sbjct: 598 -KKPAPTTPKEPAPTTPKET------APTTP--KKLTPTTPE----KLAPTTPEKPAPTT 644
Query: 1500 HLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYP 1545
+ A + PAP+ P AA+ TP P P E P
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/210 (21%), Positives = 71/210 (33%), Gaps = 10/210 (4%)
Query: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT------PPPTLHLVPEPAAP 935
++++ S +TS++ APT P ++ K P P PT P P
Sbjct: 304 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 363
Query: 936 PPPPPRTFQMV-TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
P P T + TTP P + P+ + A P P +T+ P +
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423
Query: 995 PAASVLVSGQAPSGTPT---APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAA 1051
S + + P+ T AP+ PAP P P E + A
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 1052 SSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
+ P KP+ + K P +KE
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513
Score = 42.4 bits (98), Expect = 0.004
Identities = 70/327 (21%), Positives = 103/327 (31%), Gaps = 46/327 (14%)
Query: 1231 APGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMP 1290
AP A +P P P + +P+ A ++ S ++ + + P
Sbjct: 483 APTAPKKPAPTTPKE---------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533
Query: 1291 SRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPP 1350
++ P T A + K + T +P P PA EP P P
Sbjct: 534 TKEPAPTTTKSAPTTP----KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 589
Query: 1351 PPPPPTGQMNGTVDHPPPAAPERK----PLGTAPHCPRLPLRKTYRENVGGPGAPEG--- 1403
P PT T P P P+ P TAP P+ L T E + P PE
Sbjct: 590 KEPAPT-----TTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLA-PTTPEKPAP 642
Query: 1404 -TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
TP A P P +E + A P EPA + + +P
Sbjct: 643 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-----------NTPKEPAPTTPK---EP 688
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRT---- 1518
P P K +P + + + + T + + + P T
Sbjct: 689 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748
Query: 1519 PAPSYPHAASAGTPASPPPLHRPEAYP 1545
PAP+ P + TP P P E P
Sbjct: 749 PAPTTPKGTAPTTPKEPAPTTPKEPAP 775
Score = 32.7 bits (73), Expect = 2.8
Identities = 39/177 (22%), Positives = 61/177 (34%), Gaps = 11/177 (6%)
Query: 1337 PATLKVAEPP-PRPPPPPPPTGQMNGTVDHPPPAAPER-KPLGTAPHCPRLPLRKTYREN 1394
P T K P P+ P P P G T+ P P P++ P AP + P T +
Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT--SD 816
Query: 1395 VGGPGAPEGTPAGRARGGS------PAP-LPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
P P+ T + + PAP P TS + E +
Sbjct: 817 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 876
Query: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSA 1504
PE +A + + PG+P K + P++ + + +D T +A
Sbjct: 877 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 933
Score = 32.3 bits (72), Expect = 3.7
Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 1/75 (1%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
P P T P P PPP T +++ P + P + P P K
Sbjct: 831 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 890
Query: 1393 ENVGGPGAP-EGTPA 1406
+ PG P TPA
Sbjct: 891 NSPKEPGVPTTKTPA 905
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 126 bits (316), Expect = 2e-28
Identities = 144/511 (28%), Positives = 187/511 (36%), Gaps = 89/511 (17%)
Query: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS---PGLASS 673
P ++ P P + TP P PP P P PP P PS P S+
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 674 PEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDP 733
V + + T +Q S +F P + P + VP + +V PPP P
Sbjct: 661 APMFV--KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVV--PPPPPPP 716
Query: 734 APATPVA-----KGAGLGPQAPDSQASPAP-----APQIPAAAPLKGPGPSSSPS-LPHQ 782
P TP + K A P P A P P I AP P P P+ LP Q
Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776
Query: 783 APLGDSPHLPSP--------------HPTRPPSRPPSRPQSVSRPPSEPPLHPCPP-PQA 827
AP +P+P PT P PP++ Q PP P PP P
Sbjct: 777 APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836
Query: 828 PPTLPGIFVIQNQLGVPPPAS-NPAPTA--------PGPPQPPLRPQSQPPEGPLPPAP- 877
PPTLP Q+ PPP+ +P P+ P PP PP +SQ PL P P
Sbjct: 837 PPTLP---KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM-ESQ----PLKPVPA 888
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP 937
++ P S + A S +P P+P DF PP + P PPP+ P PA PPP
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSP-DFPP--PPPESSLVFPPPPPS----PVPAPPPP 941
Query: 938 PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS--- 994
PPP +P P P G P PQ ++S+ +
Sbjct: 942 PPP-----TASPTPDKSGSPGKKTSKTSSPGG-------KKPPPTPQRNSSIKSSSGAEH 989
Query: 995 -----PAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLP------ 1043
P+ LVS P +PS P P A P P + NLP
Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA-----PPKPGKLNLSGVNLPGVLQQG 1044
Query: 1044 TLNVAKAASSGPGKPSGLQYESKLSGLKKPP 1074
++ SG GK S +++ S S PP
Sbjct: 1045 CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075
Score = 91.3 bits (225), Expect = 7e-18
Identities = 114/437 (26%), Positives = 152/437 (34%), Gaps = 86/437 (19%)
Query: 735 PATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSP 794
P T + P+ + P+P +P P P P P P P +P S
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 795 HPTRPPSRPPSRPQSVSRPPSEPPLHPCPPP-QAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P +R Q+ S+ P PP Q+ P I V N + VPPP P P
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV-VPPPPPPPPPP 719
Query: 854 APG-------------------PPQPPLR-----------PQSQPP----EGPLPP-APH 878
PG P PPL+ P + PP PLPP AP
Sbjct: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 879 LP----PSSTSSAVASSSETSSRLPAPT----PSDFQLQFPPSQGPHKSPT-----PPPT 925
P P+ TS+ + T + P PT P+ Q FP S P PT PPPT
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT 839
Query: 926 LHLVPEPAAPPPPP-----PRTFQMVTTPFPALPQPKAL-LERFHQVPSGIILQNKAGGA 979
L A PPP P + + + FP P P A+ + VP+ + A
Sbjct: 840 LPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV--------A 891
Query: 980 PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFA 1039
P +P + P P++ + S P P + P P P PP P
Sbjct: 892 PQSP-PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP------- 943
Query: 1040 SNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPD 1099
PT + S PGK + S G K PPT Q + K HP+
Sbjct: 944 ---PTASPTPDKSGSPGKKT--SKTSSPGGKKPPPTPQRNSSI-------KSSSGAEHPE 991
Query: 1100 YKTAFPSFEDALHRLLP 1116
K PS + + + P
Sbjct: 992 PKR--PSVDSLVSKFTP 1006
Score = 90.9 bits (224), Expect = 9e-18
Identities = 181/738 (24%), Positives = 229/738 (31%), Gaps = 159/738 (21%)
Query: 335 PLVPAPNVILHRTP-TPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKA 393
PL P P ++ TP T QP P PP P P P L Q P A P
Sbjct: 608 PLSPQPKIV---TPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Query: 394 PQNLTFMAAGKAGQNV-VLSGFPAPALQANVFKQPPATT--TGAAPPQPPGALSKPMSVH 450
+ T A Q+ L P P + + +P G PP PP
Sbjct: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP---------- 714
Query: 451 LLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLI 510
P PG L AP Q SA P
Sbjct: 715 ----------PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP------------------- 745
Query: 511 ANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
PL + V HI AP P P+ A P +
Sbjct: 746 ------------PLKIHQV---------QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVT 784
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630
PAP + PP+ P P A A P + P+P PP
Sbjct: 785 IPAPTSTKTVAPVVTQAAPPTPT-----------PPVPPAKKQPAFPASYIPPSPPTPPV 833
Query: 631 VSTPLPLGLQQPQAQQPPQAPTPQAAAP-------PQATTPQPSPGLASSPEKIVLGQPP 683
P L QQ +PP P+P + P Q P P + S P K V
Sbjct: 834 PVPPPTLPKQQSFCAKPP--PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVA 891
Query: 684 SATPTAILTQDSLQMFLPQERSQQPL-SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
+P A+ + Q S P+ S + P +S++ PPP+ PAP
Sbjct: 892 PQSPPAVKAKPKWQ------PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP------- 938
Query: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSP--SLPHQAPLGDSPHLPSPHPTRPP 800
P P ASP P + +P K +SSP P P +S S P
Sbjct: 939 ----PPPPPPTASPTPD---KSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991
Query: 801 SRPPSRPQSVSR--PPSE---PPLHPCPPPQAPPTLPGIFVIQNQLGVPPP-------AS 848
+ PS VS+ PP+E P PPP APP PG N GV P S
Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK-PGKL---NLSGVNLPGVLQQGCVS 1047
Query: 849 NPAPTAPGP--------PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900
AP G P PP PP PP LP S TS ++
Sbjct: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPP----PPETELPLPPIEIPAVFSGNTSPKVAV 1103
Query: 901 PTPSDFQ------LQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALP 954
P Q + PP P ++ + T + E P Q+ T+P +L
Sbjct: 1104 VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP---QVPTSPKSSLS 1160
Query: 955 -QPKAL------LERFHQVPSGIILQNKAGGAPAAPQTSTSLGP----LTSPAASVLVSG 1003
QP L L+R G + + P A +L P L S G
Sbjct: 1161 VQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGG 1220
Query: 1004 QAPSGTPTAPSHAPAPAP 1021
SG T P PAP
Sbjct: 1221 SHISGYATL-RRGPPPAP 1237
Score = 50.8 bits (120), Expect = 1e-05
Identities = 138/607 (22%), Positives = 196/607 (32%), Gaps = 125/607 (20%)
Query: 179 QALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVV 238
Q LVPP VV P P G L+P P LP S A L + +Q +
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTP-GSAMAQLKPAPCAPSLPQFS---APPPPLKIHQVQHI 755
Query: 239 GQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVA 298
Q P P+ L A P VT+ + + A +V Q
Sbjct: 756 TQVAPPTPPPPP-------PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQ-------- 800
Query: 299 TTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGV 358
A+ PT TP P P +S + P+P PTP P P
Sbjct: 801 --------------AAPPTPTPPVPPAKKQPAFPASYIPPSP-------PTPPVPVPPPT 839
Query: 359 LP--------PKLYQLTPKP---------FAPAGATLTIQGEPGALPQQPKAPQNLTFMA 401
LP P L+P P F P ++ +P APQ+ +
Sbjct: 840 LPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVK 899
Query: 402 AGKAGQ----NVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSS 457
A Q V FP P ++++ PP + APP PP + P GS
Sbjct: 900 AKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPD---KSGSP 956
Query: 458 IVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTN 517
++ PG G PQ+ S++ ++ G + P +
Sbjct: 957 GKKTSKTSSPG-------GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAE 1009
Query: 518 QNLAGPLSLGPVLAPH-------SGAHSAHILSAAPIQVGQPALF-QMPVSLAAGSLPTQ 569
+L P AP SG + +L + P L + S+ P
Sbjct: 1010 SGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPS 1069
Query: 570 SQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAP-VLTVQPAPQ-- 626
P P T + LPP + PA +G +P V V P PQ
Sbjct: 1070 DSDFPPPPPETE----LPLPPIEI--------------PAVFSGNTSPKVAVVNPQPQQW 1111
Query: 627 -------APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS----PGLASSPE 675
APP + QA+ Q PT P T+P+ S PG +
Sbjct: 1112 SKMSVKKAPPPTRPKRNDSTRLTQAEISEQ-PTMATVVPQVPTSPKSSLSVQPGFLADLN 1170
Query: 676 KI-----------VLGQPPSATPTAILTQDSLQMFLPQERS-QQPLSAEGPHLSVPASVI 723
+ + + A PTA + +L P+ S QQ G H+S A+ +
Sbjct: 1171 RTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYAT-L 1229
Query: 724 VSAPPPA 730
PPPA
Sbjct: 1230 RRGPPPA 1236
Score = 47.0 bits (110), Expect = 1e-04
Identities = 92/393 (23%), Positives = 124/393 (31%), Gaps = 96/393 (24%)
Query: 1211 PIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGS----PSVTWARASS 1266
P AS LP P P PPP LP++ G A ++T + +S
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNAS 677
Query: 1267 SLSSS---------SSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLK-------- 1309
S + S S + +G +P PP + LK
Sbjct: 678 QHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737
Query: 1310 ---------LKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPP----PPPT 1356
LKI Q V H T + P PPPPP + PP PP P P PT
Sbjct: 738 PQFSAPPPPLKIHQ------VQHITQVAPPTPPPPPP--IPAPLPPQAPPKPLVTIPAPT 789
Query: 1357 G---------QMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAG 1407
Q PP +++P A + P P P P P
Sbjct: 790 STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV------PVPPPTLPKQ 843
Query: 1408 RARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGD-PDWEA 1466
++ P P P +++++A+ PPP P A +Q P A
Sbjct: 844 QSFCAKPPPSPL---SPVPSVVKQIASQFP---------PPPTPPAMESQPLKPVPANVA 891
Query: 1467 PGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPS--YP 1524
P PPA + K P +S SP P P S +P
Sbjct: 892 PQSPPAVKAK---PKWQPSSIPVPSP--------------------DFPPPPPESSLVFP 928
Query: 1525 HAASAGTPASPPPLHRPEAYPPSSHNGGLGART 1557
+ PA PPP P A P +G G +T
Sbjct: 929 PPPPSPVPAPPPP-PPPTASPTPDKSGSPGKKT 960
Score = 45.8 bits (107), Expect = 3e-04
Identities = 128/582 (21%), Positives = 185/582 (31%), Gaps = 84/582 (14%)
Query: 987 TSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLN 1046
TSL P SP ++ A +P P P P P PP P LP+ +
Sbjct: 603 TSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPP---------LPSQS 653
Query: 1047 VAKAASSGP-----GKPSGLQYESKLSGLKKPPTLQPSKEACFLEH--LHKHQGSVLHPD 1099
A S+ P + LQ S+ SG P P ++ ++ L G V P
Sbjct: 654 APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP 713
Query: 1100 YKTAFPSFEDALHRLLPYHVYQG-----ALPSPSDYHKVDEEFETVSTQLLKRTQAMLNK 1154
P+ A+ +L P A P P H+V TQ+ T
Sbjct: 714 PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQH-----ITQVAPPTPPPPPP 768
Query: 1155 YRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAA 1214
L ++ P +V I KT + Q A P V ++
Sbjct: 769 IPAPLPPQA----PPKPLVTIPAP--TSTKTVAPVVTQAAPPTPTPPVPPAK-------- 814
Query: 1215 SSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSS 1274
+ P P S P T P P P L + P + S + +S
Sbjct: 815 -----KQPAF-PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868
Query: 1275 SSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPP 1334
+ A E P+ +P +S +K K K + V P PP
Sbjct: 869 FPPPPTPPAMESQPL----KPVPANVAPQSPPAVKAKPKWQPSSIPVP-----SPDFPPP 919
Query: 1335 PPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYREN 1394
PP ++L PPP P P PPP PP A+P G+ P +KT + +
Sbjct: 920 PPESSLVFPPPPPSPVPAPPP--------PPPPTASPTPDKSGS-------PGKKTSKTS 964
Query: 1395 VGG----PGAPEGTPAGRARGGSPAPLPAK--VDEATSGLIRELAAVEDELYQRMLKGPP 1448
G P P+ + ++ G+ P P + VD S + P
Sbjct: 965 SPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP 1024
Query: 1449 PEPAASAAQGTGDPDWEAPGLPPAK------RRKSESPDVDQASFSSDSPQDDTLTEHLQ 1502
P+P G P G AK R K + SD P TE
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084
Query: 1503 SAID--SILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPE 1542
I+ ++ + +P P S + PP RP+
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPK 1126
Score = 40.4 bits (93), Expect = 0.013
Identities = 47/194 (24%), Positives = 71/194 (36%), Gaps = 20/194 (10%)
Query: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRT 942
S+ + + S + + L P ++ P + P PPP P P PPPPPP
Sbjct: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP-- 647
Query: 943 FQMVTTPFPALPQPKALLERFHQVPSGIILQNKA--GGAPAAPQTSTSLGPLTSPAASVL 1000
P + P + F + + LQN + GA P T P + SV
Sbjct: 648 ----PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT-----PPVMQSQSVK 698
Query: 1001 VSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSG 1060
P P P P P + + L PA A +LP +A P K
Sbjct: 699 PQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA---PCAPSLPQF----SAPPPPLKIHQ 751
Query: 1061 LQYESKLSGLKKPP 1074
+Q+ ++++ PP
Sbjct: 752 VQHITQVAPPTPPP 765
Score = 38.9 bits (89), Expect = 0.039
Identities = 71/303 (23%), Positives = 98/303 (32%), Gaps = 78/303 (25%)
Query: 1264 ASSSLSSSSSSSSAASSL------------DADEDGPMPSRNRPPIKTYEARSRIGLKLK 1311
+SSS+ S SSSSS S D G + S++ EA R G +L+
Sbjct: 530 SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKR-GTQLE 588
Query: 1312 IKQEAGLSKVVHN-TALDPVHQPPPPPATLKVAE---------PPPRPPPPPPPTGQMNG 1361
+A + + T+L P P P T A PPP PPPPPPP
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPP------ 642
Query: 1362 TVDHPPPAAPERKPLGTAPHCPRLPLRKTY------RENVGGPGAPEGTPAGRARGGSPA 1415
PPP P + P T ++ G P P +++ P
Sbjct: 643 --PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP- 699
Query: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR 1475
++ +G++ PPP P +A P AP LP
Sbjct: 700 ----QILVPPNGVVPPPPP------------PPPPPTPGSAMAQLKPAPCAPSLP----- 738
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
FS+ P I + ++ Q TP P P A A P
Sbjct: 739 ----------QFSAPPP---------PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 1536 PPL 1538
PL
Sbjct: 780 KPL 782
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 126 bits (316), Expect = 2e-28
Identities = 257/992 (25%), Positives = 338/992 (34%), Gaps = 233/992 (23%)
Query: 61 LNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEA 120
L+PEP P P + F G G S A P + ++ T +A
Sbjct: 510 LDPEPPGP-PDPPVAF---------GKGYGSAPSSSASSPASSSASAATSFSLGSGTFKA 559
Query: 121 EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQA 180
+ E G P P P GAGG A + + L P + P +V
Sbjct: 560 Q-ESGQGSTAGPLRPP------PPGAGGPATPSKATRFL-PMDPATFRRKRPESV---GG 608
Query: 181 LVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQ 240
L PP V A P G GN+ LQ + L GG AP G
Sbjct: 609 LEPPGPSVIAA-------PPSGGGNI-LQTLV-LPPNKEEQEGGGARVPSAPAPSLAYGA 659
Query: 241 PVMALNTPTSQLLAKQV-PVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVAT 299
P L+ P + ++ V PVS S PV +AS G + + A
Sbjct: 660 PAAPLSRPAATMVTNVVRPVS---------STPVPIASKPFPTSGRAEASPNDTAGARTE 710
Query: 300 TLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVL 359
G+ V P G+P G L + ++ PAP+++ AG L
Sbjct: 711 MGTGSRV---------PGGSPLGVSLVYSDKKSAAATSPAPHLV------------AGPL 749
Query: 360 PPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419
L APA T + G PG P A Q F+A G G +G A A
Sbjct: 750 ------LGTVGKAPATVTNLLVGTPGYGAPAPPAVQ---FIAQGAPGGGTT-AGSGAGA- 798
Query: 420 QANVFKQPPATTTGAAPPQP-------PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF 472
G+ P P PGAL K + Q Q+
Sbjct: 799 -------------GSGPNGPVPLGILQPGALGKAGGIT------------------QVQY 827
Query: 473 LLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAP 532
+LP LPQQL PA A AP T + P T S+ L P
Sbjct: 828 ILP-----TLPQQLQVAPA-------PAPAPGTKAAAPSGPAPTT-------SIRFTLPP 868
Query: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSA 592
+ + + + AP G P L QS P+ P A +V PP
Sbjct: 869 GTSTNGKVLAATAPTP-GIPIL--------------QSVPSAPPPKAQSVSPVQAPPPGG 913
Query: 593 VAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQA---QQPPQ 649
A L LV A P+ + QP P P S P+ G Q P P
Sbjct: 914 SAQLLPGKVLVPLAAPSMSVRGGG---AGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVP 970
Query: 650 APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFL---PQERSQ 706
TP PP +P PG S P+K++L P S T + + + L P
Sbjct: 971 VSTPSGLVPP--LSPATLPGPTSQPQKVLL--PSSTRITYVQSAGGHALPLGTSPASSQA 1026
Query: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQA--SPAPAPQIPA 764
+++ GP SV P PA P+ AG P Q SP P+PQ+P
Sbjct: 1027 GTVTSYGPTSSVALGFTSLGP---SGPAFVQPLLS-AGQAPLLAPGQVGVSPVPSPQLPP 1082
Query: 765 AAPLKGPGP------SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP 818
A G GP S SP+ APL +P PPS +V+ + P
Sbjct: 1083 ACAAPG-GPVITAFYSGSPAPTSSAPLA-----------QPSQAPPSLVYTVATSTTPPA 1130
Query: 819 LHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP-------LRPQSQPPEG 871
P + PP P + PAPT+P P + P++Q P
Sbjct: 1131 ATILP--KGPPA--------------PATATPAPTSPFPSATAGSMTYSLVAPKAQRPS- 1173
Query: 872 PLPPAPHLPPSSTSSAVASSSET-SSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVP 930
P AP ++ +S S E +S P P P P GP + PT P + L
Sbjct: 1174 --PKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQ-----PLEPGPVREPTAPES-ELEG 1225
Query: 931 EPAAPPPPP-PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
+P P PPP P T+ P LP P ER + P+T S
Sbjct: 1226 QPTPPAPPPLPETWTPTARSSPPLPPPAE--ERT---------------SAKGPETMASK 1268
Query: 990 GPLTSPAASVLVSGQAPSGTP-TAPSHAPAPA 1020
P +S V G G P T PS APAPA
Sbjct: 1269 FPSSSSDWRVPGQGLENRGEPPTPPSPAPAPA 1300
Score = 100 bits (248), Expect = 1e-20
Identities = 224/867 (25%), Positives = 309/867 (35%), Gaps = 153/867 (17%)
Query: 269 PSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLN-GNSVF----GGAGAASAPTGTP--- 320
P PV S + + SA+ AT+ + G+ F G G+ + P P
Sbjct: 518 PDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPG 577
Query: 321 SGQPLAVAPGLGSSPLVPAP---------NVILHRTPTPIQPKPAG--------VLPPKL 363
+G P + P+ PA + P+ I P+G VLPP
Sbjct: 578 AGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNK 637
Query: 364 YQL----TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419
+ P APA + G P A +P A +T + + V ++ P P
Sbjct: 638 EEQEGGGARVPSAPAPSLA--YGAPAAPLSRPAATM-VTNVVRPVSSTPVPIASKPFPT- 693
Query: 420 QANVFKQPPATTTGAAPPQPPGAL---SKPMSVHLL---NQGSSIVIPAQHMLPGQNQFL 473
+ + P T GA G+ P+ V L+ + ++ PA H++ G
Sbjct: 694 -SGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGT 752
Query: 474 LPGAPAVQLPQQLSA----LPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPV 529
+ APA + PA Q +A AP GG + GP+ LG +
Sbjct: 753 VGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPG-GGTTAGSGAGAGSGPNGPVPLG-I 810
Query: 530 LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP 589
L P + + I I P Q+ V+ A P AP+GPA TT ++ TLP
Sbjct: 811 LQPGALGKAGGITQVQYILPTLPQ--QLQVAPAPAPAPGTKAAAPSGPAPTTSIR-FTLP 867
Query: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649
P + +G V AT A P+L Q P APP
Sbjct: 868 PGT-----STNGKVLAAT---APTPGIPIL--QSVPSAPP-------------------- 897
Query: 650 APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL 709
P Q+ +P QA P S L P K+++ P A P+ M + + QPL
Sbjct: 898 -PKAQSVSPVQAPPPGGSAQLL--PGKVLV---PLAAPS---------MSVRGGGAGQPL 942
Query: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
P SVP P P PV+ +GL P SPA P P + P K
Sbjct: 943 PLVSPPFSVPVQNGAQPPSKIIQLTPV-PVSTPSGLVPPL-----SPATLPG-PTSQPQK 995
Query: 770 GPGPSSS------PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV---SRPPSEPP-L 819
PSS+ + H PLG SP S S P+ ++ S PS P +
Sbjct: 996 VLLPSSTRITYVQSAGGHALPLGTSP--ASSQAGTVTSYGPTSSVALGFTSLGPSGPAFV 1053
Query: 820 HPC-PPPQAPPTLPGIFVIQNQLGVPP---PASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875
P QAP PG Q+GV P P PA APG P P P
Sbjct: 1054 QPLLSAGQAPLLAPG------QVGVSPVPSPQLPPACAAPGGPVITAFYSGSP--APTSS 1105
Query: 876 APHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP 935
AP PS ++ + TS+ PA T K P P T P P +P
Sbjct: 1106 APLAQPSQAPPSLVYTVATSTTPPAATILP------------KGPPAPATA--TPAPTSP 1151
Query: 936 PPPPPR---TFQMVTTPFPALPQPKA---LLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
P T+ +V P P PKA + +P G +G AP+
Sbjct: 1152 FPSATAGSMTYSLVA-PKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEP 1210
Query: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL-LPAENKAFASNLPTLNVA 1048
GP+ P A P TP AP P A PPL PAE + A T+
Sbjct: 1211 GPVREPTAPESELEGQP--TPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASK 1268
Query: 1049 KAASSGPGKPSGLQYESKLSGLKKPPT 1075
+SS + G E++ +PPT
Sbjct: 1269 FPSSSSDWRVPGQGLENR----GEPPT 1291
Score = 89.4 bits (220), Expect = 3e-17
Identities = 185/762 (24%), Positives = 255/762 (33%), Gaps = 137/762 (17%)
Query: 426 QPPATTTGAAPPQPPGALSKPM----SVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQ 481
+PP PP PP A K S + SS A G F +
Sbjct: 507 RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
Query: 482 LPQQLSALPANVGGQILAAAAPHTGGQLIANPILT-----NQNLAGPLSLGP-VLA--PH 533
L P GG A P + + T +++ G GP V+A P
Sbjct: 567 TAGPLRPPPPGAGGP----ATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPS 622
Query: 534 SGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAV 593
G + L P + Q S A SL + AP A T++ V P S+
Sbjct: 623 GGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSS- 681
Query: 594 AMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTP--LPLGLQQPQAQQPPQA- 650
TP + P + EA+P T + P PLG+ + + A
Sbjct: 682 ----TPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAA 737
Query: 651 --PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQP 708
P P A P T +P ++ +++G P P Q F+ Q
Sbjct: 738 TSPAPHLVAGPLLGTVGKAPATVTN---LLVGTPGYGAPAPPAVQ-----FIAQGAPGGG 789
Query: 709 LSA-------EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761
+A GP+ VP ++ P T V PQ +PAPAP
Sbjct: 790 TTAGSGAGAGSGPNGPVPLGIL--QPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPG 847
Query: 762 IPAAAPLKGPGPSSSPSLPHQAPLGDSPH-----LPSPHPTRP-----PSRPPSRPQSVS 811
AAAP GP+ + S+ P G S + +P P P PS PP + QSVS
Sbjct: 848 TKAAAP---SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVS 904
Query: 812 RPPSEPP-----------LHPCPPP----------QAPPTLPGIFVIQNQLGVPPPAS-- 848
+ PP L P P Q P + F + Q G PP+
Sbjct: 905 PVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKII 964
Query: 849 --NPAPTA-PGPPQPPLRPQSQPPEGPLP-PAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
P P + P PPL P + P GP P L PSST S+ + +P+
Sbjct: 965 QLTPVPVSTPSGLVPPLSPATLP--GPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPA 1022
Query: 905 DFQLQFPPSQGPHKS---------PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQ 955
Q S GP S P+ P + + P P + P P LP
Sbjct: 1023 SSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPP 1082
Query: 956 PKALLERFHQVPSGIILQNKAGGAPA----APQTSTSLGP----------LTSPAASVLV 1001
A P G ++ G+PA AP S P T PAA++L
Sbjct: 1083 ACA-------APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILP 1135
Query: 1002 SGQAPSGTPTAPSHAPAPAPMA-----------ATGLPPLLPAENKAFASNLPTLNVAKA 1050
G T T +P P+ A A P P + KA +++P +
Sbjct: 1136 KGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAG 1195
Query: 1051 ASSGPG-------KPSGLQY----ESKLSGLKKPPTLQPSKE 1081
AS PG +P ++ ES+L G PP P E
Sbjct: 1196 ASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPE 1237
Score = 57.8 bits (138), Expect = 8e-08
Identities = 203/902 (22%), Positives = 286/902 (31%), Gaps = 180/902 (19%)
Query: 135 QPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSV 194
Q A GG T AG A +GP P G G +T + P + + L V
Sbjct: 783 QGAPGGG--TTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILP--TLPQQLQV 838
Query: 195 QPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLA 254
P P PG + P T+ L P V+A PT
Sbjct: 839 AP----------APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG--- 885
Query: 255 KQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAAS 314
+P+ + SA P P G+ ++ + +A SV GG
Sbjct: 886 --IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAP--SMSVRGGGAGQP 941
Query: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFA-- 372
P +P P +V G+ P P+ I+ TP P+ P+G++PP P P +
Sbjct: 942 LPLVSP---PFSVPVQNGAQP----PSKIIQLTPVPVST-PSGLVPPLSPATLPGPTSQP 993
Query: 373 -----PAGATLTIQGEPG--ALP--QQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423
P+ +T G ALP P + Q T + G V GF +
Sbjct: 994 QKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSS--VALGFTSLGPSGPA 1051
Query: 424 FKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF--LLPGAPAVQ 481
F QP + G AP PG + ++ S +P PG G+PA
Sbjct: 1052 FVQP-LLSAGQAPLLAPGQVG-------VSPVPSPQLPPACAAPGGPVITAFYSGSPAPT 1103
Query: 482 LPQQL---SALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS 538
L S P ++ + + P L P P S P S +S
Sbjct: 1104 SSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYS 1163
Query: 539 AHILSA------APIQVGQPALFQMPV-SLAAGSL----PTQSQPAPAGP-----AATTV 582
A AP +V + A+ +PV S AG+ P QP GP A +
Sbjct: 1164 LVAPKAQRPSPKAPQKV-KAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESE 1222
Query: 583 LQGVTLPPSAVAMLNT--PDGLVQPATPAAA---TGEAAPVLTVQPAPQAPPAVSTPLPL 637
L+G PP+ + T P P P A T P P + P
Sbjct: 1223 LEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVP-GQ 1281
Query: 638 GLQQ----PQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAIL-T 692
GL+ P P AP ++++ + + E G+ P + T
Sbjct: 1282 GLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKT 1341
Query: 693 QDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA---------KGA 743
DS+ + E + AE P P V+ P P +P A K +
Sbjct: 1342 FDSVDNRVLSEVDFEERFAELPEFR-PEEVL---PSPTLQSLATSPRAILGSYRKKRKNS 1397
Query: 744 GLGPQAPDSQASP----------APAPQIPAAAPLKG----------------------- 770
AP+ SP + P P +A +G
Sbjct: 1398 TDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDK 1457
Query: 771 -PGPSSSPSLPHQAPL-----GDSPHLPSPHPT-----RPPSRPPSRP--QSVSRPPSEP 817
P S +L + L D PS T R PS+ Q R +
Sbjct: 1458 VPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQK 1517
Query: 818 PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAP 877
+ P + PP + L VPPP A AP P P GP
Sbjct: 1518 IMQAATPTEQPPGA------EAPLPVPPPTGTAAAPAPTP---------SPAGGP----- 1557
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP 937
P+S S S S T+ P P PP GP + P P+P+ PPP
Sbjct: 1558 --DPTSPS----SDSGTAQAAPPLPP-------PPESGPGQ-----PGWEGAPQPSPPPP 1599
Query: 938 PP 939
P
Sbjct: 1600 GP 1601
Score = 44.7 bits (104), Expect = 7e-04
Identities = 41/172 (23%), Positives = 63/172 (36%), Gaps = 34/172 (19%)
Query: 745 LGPQAPDSQASPAPAPQIPAAAPL---KGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801
L P PD P+ A Q PA+ P+ + P+ S ++ H+ P G +
Sbjct: 44 LAPSQPDPSVQPSEAQQ-PASHPVASNQSKEPAESAAVAHERPPGGTG------------ 90
Query: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861
S P PP CP P + V+++ G PP A PG P+
Sbjct: 91 ---------SADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLD 141
Query: 862 LRPQS---------QPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
+S PE LP P + + SA+ ++SS +P+
Sbjct: 142 SETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPN 193
Score = 44.3 bits (103), Expect = 0.001
Identities = 185/854 (21%), Positives = 265/854 (31%), Gaps = 132/854 (15%)
Query: 636 PLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG--------------- 680
PL + P PP A + P ++ P+ AS+ LG
Sbjct: 509 PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA 568
Query: 681 ---QPPSATPTAILTQDSLQMFLPQE----RSQQPLSAEGPHLSVPASVIVSAPPPAQDP 733
+PP T FLP + R ++P S G L P +++APP
Sbjct: 569 GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGG--LEPPGPSVIAAPPSGGGN 626
Query: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIP---AAAPLKGPGPSSSPSLPHQAPLGDSPH 790
T V + ++ APAP + AAPL P + ++ P
Sbjct: 627 ILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPI 686
Query: 791 LPSPHPTRPPSRPPSRPQSV----------SRPPSEPPLHPC----PPPQAPPTLPGIFV 836
P PT R + P SR P PL A T P +
Sbjct: 687 ASKPFPTS--GRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHL 744
Query: 837 IQNQL-----GVPPPASN-----PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSS 886
+ L P +N P AP PP Q P G ++ S
Sbjct: 745 VAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGG----------TTAGS 794
Query: 887 AVASSSETSSRLPAPT--PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQ 944
+ S + +P P +Q + PT P L + P PA P P T
Sbjct: 795 GAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPA----PAPGT-- 848
Query: 945 MVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS---PAASVLV 1001
P+ P P + RF +P G K A A L + S P A +
Sbjct: 849 --KAAAPSGPAPTTSI-RF-TLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVS 904
Query: 1002 SGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLN--VAKAASSGPGKPS 1059
QAP P S P + P + LP ++ + +G PS
Sbjct: 905 PVQAP---PPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPS 961
Query: 1060 GLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHV 1119
+ + + + P L P L VL P T + A LP
Sbjct: 962 KIIQLTPVP-VSTPSGLVPPLSPATLPGPTSQPQKVLLPS-STRITYVQSAGGHALPL-- 1017
Query: 1120 YQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMF 1179
G P+ S V T S L + L V P +
Sbjct: 1018 --GTSPASSQAGTVTSYGPTSSVAL---------GFTSLGPSGPAFVQPLLSAGQAPLLA 1066
Query: 1180 IQEEKTTLALDKQL--AKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQ 1237
+ + QL A P V ++ G P SS P P S A++
Sbjct: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
Query: 1238 PPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
PP ++ G +P+ +S S+++ S S + P P + P
Sbjct: 1127 TPP---AATILPKGPP--APATATPAPTSPFPSATAGSMTYSLVAPKAQRPSP---KAPQ 1178
Query: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDP--VHQPPPPPATLKVAEPPPRPPPPP-- 1353
K A + I + +G L+P V +P P + L+ PP PPP P
Sbjct: 1179 KVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPET 1238
Query: 1354 -PPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKT-YR------ENVGGPGAPEGTP 1405
PT + + + PPPA G + P + +R EN G P P
Sbjct: 1239 WTPTARSSPPL--PPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPP--- 1293
Query: 1406 AGRARGGSPAPLPA 1419
SPAP PA
Sbjct: 1294 -------SPAPAPA 1300
Score = 40.4 bits (93), Expect = 0.013
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 29/148 (19%)
Query: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
PSA TA +F P + Q E + A+ PP A+ P P P
Sbjct: 1485 PSAQATAAFQARYADIF-PSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGT 1543
Query: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
A A+PAP P +P GP P+S P DS + P PP
Sbjct: 1544 A----------AAPAPTP-----SPAGGPDPTS--------PSSDSGTAQAAPPLPPP-- 1578
Query: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPT 830
P S P +P E P PPP P T
Sbjct: 1579 PESGP---GQPGWEGAPQPSPPPPGPST 1603
Score = 40.4 bits (93), Expect = 0.013
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 27/99 (27%)
Query: 864 PQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
P QPP G P P PP+ T++A PAPTPS P+ GP PT P
Sbjct: 1524 PTEQPP-GAEAPLPVPPPTGTAAA-----------PAPTPS-------PAGGP--DPTSP 1562
Query: 924 PTLHLVPEPAAPPPPPPRT------FQMVTTPFPALPQP 956
+ + A P PPPP + ++ P P P P
Sbjct: 1563 SSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
Score = 39.3 bits (90), Expect = 0.030
Identities = 63/250 (25%), Positives = 87/250 (34%), Gaps = 39/250 (15%)
Query: 1182 EEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPH 1241
+E+ T + + E P+ R + P+ SS H P PL PG PP
Sbjct: 468 KERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRP---PLDPEPPG-----PPD 519
Query: 1242 LPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDG----PMPSRNRPPI 1297
P +G A S + + ASSS S+++S S + + A E G P R PP
Sbjct: 520 PPVAFGKGYGSAPSSSASS--PASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPP- 576
Query: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTG 1357
A SK +DP P ++ EPP PP+G
Sbjct: 577 -------------GAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSG 623
Query: 1358 QMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAG-------RAR 1410
N P E + G A R+P G P AP PA R
Sbjct: 624 GGNILQTLVLPPNKEEQEGGGA----RVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPV 679
Query: 1411 GGSPAPLPAK 1420
+P P+ +K
Sbjct: 680 SSTPVPIASK 689
Score = 39.3 bits (90), Expect = 0.030
Identities = 92/410 (22%), Positives = 135/410 (32%), Gaps = 86/410 (20%)
Query: 1218 GHRLPGHGPL------SSSAPGASTQPPPHLP---------------TKLVIRHGGAGGS 1256
G R+PG PL S A+T P PHL T L++ G G
Sbjct: 714 GSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAP 773
Query: 1257 --PSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQ 1314
P+V + + +++ S A + + +GP+P P +A ++ +
Sbjct: 774 APPAVQFIAQGAPGGGTTAGSGAGAG--SGPNGPVPLGILQPGALGKAGGITQVQYILPT 831
Query: 1315 EAGLSKVVHNTALDP-----VHQPPPPPATLKVAEPP-------------PRP------- 1349
+V A P P P +++ PP P P
Sbjct: 832 LPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQS 891
Query: 1350 -PPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGR 1408
P PPP Q V PPP + G P + R G P +P
Sbjct: 892 VPSAPPPKAQSVSPVQAPPPGGSAQLLPGKV-LVPLAAPSMSVRGGGAGQPLPLVSPPFS 950
Query: 1409 ARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPA------------ASAA 1456
+ A P+K+ + T + + + L L GP +P +A
Sbjct: 951 VPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSA 1010
Query: 1457 QGTGDPDWEAPGLPPAKRRKSESPDVDQA-SFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
G P +P A S P A F+S P + L SA + L AP
Sbjct: 1011 GGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPL---LAP 1067
Query: 1516 GR-----TPAPSYPHAASA-----------GTPA--SPPPLHRPEAYPPS 1547
G+ P+P P A +A G+PA S PL +P PPS
Sbjct: 1068 GQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPS 1117
Score = 37.0 bits (84), Expect = 0.15
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 23/87 (26%)
Query: 813 PPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPG---------PPQPPLR 863
P +E PL P PPP P P PA P PT+P PP PP
Sbjct: 1529 PGAEAPL-PVPPPTGTAAAPA--------PTPSPAGGPDPTSPSSDSGTAQAAPPLPP-P 1578
Query: 864 PQSQPP----EGPLPPAPHLPPSSTSS 886
P+S P EG P+P P ST++
Sbjct: 1579 PESGPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 35.8 bits (81), Expect = 0.33
Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 18/102 (17%)
Query: 705 SQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPA 764
++QP AE P L VP PP APA + G P +P S + A
Sbjct: 1525 TEQPPGAEAP-LPVP-------PPTGTAAAPAPTPSPAGGPDPTSPSSDSGTA------Q 1570
Query: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR 806
AAP P P S P P + PSP P P + R
Sbjct: 1571 AAPPLPPPPESGPGQPG----WEGAPQPSPPPPGPSTAATGR 1608
Score = 34.7 bits (78), Expect = 0.74
Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 30/113 (26%)
Query: 1304 SRIGLKLKIKQEAGLSKVVHNTALDPVHQPP---------PPPATLKVAEPPPRPPPPPP 1354
S++ L+LKI++ K++ A P QPP PP T P P P P
Sbjct: 1503 SKVCLQLKIREVR--QKIMQ--AATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPD 1558
Query: 1355 PTGQM--NGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP 1405
PT +GT PP P P + P P G GAP+ +P
Sbjct: 1559 PTSPSSDSGTAQAAPPLPP---PPESGPGQP------------GWEGAPQPSP 1596
Score = 33.1 bits (74), Expect = 2.2
Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 14/97 (14%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626
PT+ P P G P+ +P G P +P++ +G T Q AP
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTP---SPAGGPDPTSPSSDSG------TAQAAPP 1574
Query: 627 APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT 663
PP P G QP + PQ P+P P A T
Sbjct: 1575 LPP----PPESGPGQPGWEGAPQ-PSPPPPGPSTAAT 1606
Score = 32.3 bits (72), Expect = 3.7
Identities = 88/412 (21%), Positives = 132/412 (32%), Gaps = 103/412 (25%)
Query: 1210 LPIAASSEGHRL----PGHG-PLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARA 1264
LP S+ G L P G P+ S P A PPP + ++ GGS + +
Sbjct: 866 LPPGTSTNGKVLAATAPTPGIPILQSVPSA---PPPKAQSVSPVQAPPPGGSAQLLPGKV 922
Query: 1265 SSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHN 1324
L++ S S + P+P + P S V N
Sbjct: 923 LVPLAAPSMSVRGGGA-----GQPLPLVSPP----------------------FSVPVQN 955
Query: 1325 TALDP---VHQPPPPPATLKVAEPPPRPPPPPPPTGQ-------MNGTVDHPPPAAPERK 1374
A P + P P +T PP P P PT Q + + + A
Sbjct: 956 GAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHAL 1015
Query: 1375 PLGTAPHCPRL----------------------------PLRKTYRENVGGPG------- 1399
PLGT+P + PL + + PG
Sbjct: 1016 PLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPV 1075
Query: 1400 -APEGTPAGRARGG---------SPAPLP----AKVDEATSGLIRELAAVEDELYQRML- 1444
+P+ PA A GG SPAP A+ +A L+ +A +L
Sbjct: 1076 PSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILP 1135
Query: 1445 KGPPPEPAASAAQGTGDPDWEAPGL------PPAKRRKSESPDVDQASFSSDSPQDDTLT 1498
KGPP A+ A + P A + P A+R ++P +A+ +S +
Sbjct: 1136 KGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV--GSFE 1193
Query: 1499 EHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550
PG P+ P + G P P P PE + P++ +
Sbjct: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARS 1245
Score = 32.0 bits (71), Expect = 4.8
Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 7/111 (6%)
Query: 854 APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS 913
AP P P ++P PA H S+ S A S+ + P + PP
Sbjct: 45 APSQPDPSVQPSEAQQ-----PASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPG 99
Query: 914 QGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFH 964
+SP P P H + + PPP T + + P P P+ + E H
Sbjct: 100 ATCPESPGPGPP-HPLGVVESGKGPPPTTEEEASGP-PGEPRLDSETESDH 148
Score = 32.0 bits (71), Expect = 4.8
Identities = 26/89 (29%), Positives = 30/89 (33%), Gaps = 3/89 (3%)
Query: 602 LVQPATPAAAT-GEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ 660
++Q ATP G AP+ P A TP P G P P AAPP
Sbjct: 1518 IMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAG--GPDPTSPSSDSGTAQAAPPL 1575
Query: 661 ATTPQPSPGLASSPEKIVLGQPPSATPTA 689
P+ PG PP TA
Sbjct: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPSTA 1604
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 121 bits (304), Expect = 5e-27
Identities = 160/571 (28%), Positives = 202/571 (35%), Gaps = 151/571 (26%)
Query: 498 LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
LA AAP + Q + +P P+S GPVL P + +Q
Sbjct: 640 LADAAP-SPAQCVCSP---------PVSEGPVL---------------PQSLPSLGAYQQ 674
Query: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAP 617
P AA LP S PAPA PPS P P P +T P
Sbjct: 675 PT--AAPGLPVGSVPAPA------------CPPSLQQHFPDPAMSFAPVLPPPST--PMP 718
Query: 618 VLTVQPAP--QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPE 675
QPAP Q PP ++ P PL PQ PQ P Q P P LA + +
Sbjct: 719 TGPGQPAPPGQQPPPLAQPTPL----------PQVLAPQPVVPLQPVPPHLPPYLAPASQ 768
Query: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP 735
+G P P LQM + QPL+ P + PP P
Sbjct: 769 ---VGAPAQLKP--------LQM---PQAPLQPLAQVPPQM-----------PPIPVVPP 803
Query: 736 ATPVAKGAGLGPQAPD---SQASPAPAPQIPAAA----PLKGPGPSSSPSLPHQAPLGDS 788
TP+A GL P PD + P P PQ + A L P P +SP+LP QA
Sbjct: 804 ITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQA----- 858
Query: 789 PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTL-PGIFVIQNQLGVPPPA 847
+ PHP P P R + P + P L PP A ++ + + Q P
Sbjct: 859 --VKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAF 916
Query: 848 SNPAPT--APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
APT P P ++ PP+ LPP P LPP P PT
Sbjct: 917 PQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLP------------PQPT--- 961
Query: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALP-QPKALLERFH 964
PP PT PP L P+P PP P V P PALP +P+
Sbjct: 962 ----LPPQPVLPPQPTRPPQPVLPPQPMLPPQP-------VLPPQPALPVRPE------- 1003
Query: 965 QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAA 1024
P P P +P + +L+ AP A P P AA
Sbjct: 1004 ---------------PLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAA 1048
Query: 1025 TGLPP----LLPAENK---AFASNLPTLNVA 1048
PP LLPA + F S+L T++ +
Sbjct: 1049 VLSPPLPEVLLPAAPELLPQFPSSLATVSAS 1079
Score = 120 bits (300), Expect = 1e-26
Identities = 174/629 (27%), Positives = 218/629 (34%), Gaps = 92/629 (14%)
Query: 391 PKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVH 450
P P + +AGQ G P P + P PP P + + S
Sbjct: 567 PPVPLQVQVTYHAQAGQ----PGPPEP--------EEPEADQHLLPPTLPTSATSLASDS 614
Query: 451 LLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLI 510
+ G + + Q+ L A A P Q P G +L + P G
Sbjct: 615 TFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAY-- 672
Query: 511 ANPILTNQNLAGP-LSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQ 569
Q A P L +G V AP A P + Q F P A LP
Sbjct: 673 ------QQPTAAPGLPVGSVPAP-----------ACPPSLQQH--FPDPAMSFAPVLPPP 713
Query: 570 SQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP-QAP 628
S P P GP G PP P L QP TP PV+ +QP P P
Sbjct: 714 STPMPTGP-------GQPAPPG-----QQPPPLAQP-TPLPQVLAPQPVVPLQPVPPHLP 760
Query: 629 PAVSTPLPLGLQ-QPQAQQPPQAPT-PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT 686
P ++ +G Q + Q PQAP P A PPQ P +V P T
Sbjct: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMP-----------PIPVV----PPIT 805
Query: 687 PTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGL 745
P A + D L LP + P PA ++ S P +PA P+ A
Sbjct: 806 PLAGI--DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPH 863
Query: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQ---APLGDSPHLPSPHPTRPPSR 802
P AP + P PA PL P +L A L P P+ P P+
Sbjct: 864 PPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTD 923
Query: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP-PASNPAPTAPG----- 856
P P + P P PPQ PTLP V+ Q +PP P P PT P
Sbjct: 924 VPPSPHHTVQNMRATPPQPALPPQ--PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP 981
Query: 857 -----PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
PPQP L PQ P P P PHLP + +A S PAP D Q P
Sbjct: 982 PQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGH-PAPYAVDVAAQVP 1040
Query: 912 PSQGPHKSPTPPPTLHLVPEPAAPP--PPPPRTFQMVTTPFPALPQPKALLERFHQVPSG 969
P + PP L V PAAP P P + V+ ++P A L P+
Sbjct: 1041 TVPVPPAAVLSPP-LPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATL----LPPAN 1095
Query: 970 IILQNKAGGAPAAPQTSTSLGPLTSPAAS 998
L G A P ++ P+ AS
Sbjct: 1096 PPLPGGPGIASPCPTVQLTVEPVQEEQAS 1124
Score = 107 bits (268), Expect = 7e-23
Identities = 162/578 (28%), Positives = 226/578 (39%), Gaps = 90/578 (15%)
Query: 254 AKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAA 313
++Q + G LA AA PS + S VS G V+ ++L + A + G+
Sbjct: 631 SQQSVMLGSLADAA-PSPAQCVCSPPVSE---GPVLPQSLPSLGAYQQPTAAPGLPVGSV 686
Query: 314 SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPT-PIQPKPAGVLPPKLYQLTPKPFA 372
AP PS Q P + +P++P P+ + PT P QP P G PP L Q TP P
Sbjct: 687 PAPACPPSLQQHFPDPAMSFAPVLPPPSTPM---PTGPGQPAPPGQQPPPLAQPTPLP-- 741
Query: 373 PAGATLTIQGEPGALPQQPKAPQNLTFMA-AGKAGQNVVLSGFPAPALQANVFKQPPATT 431
+ +P QP P ++A A + G L P Q P
Sbjct: 742 ------QVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP--------QAPLQP 787
Query: 432 TGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPG----APAVQLPQQLS 487
PPQ P P L G + PA LP +P +PAV LP +
Sbjct: 788 LAQVPPQMPPIPVVPPITPL--AGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAA 845
Query: 488 AL-PANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAP 546
L PA+ + A PH G +A P T + P++ A + +L+ AP
Sbjct: 846 PLPPASPALPLQAVKLPHPPGAPLAMPCRT-------------IVPNAPA-TIPLLAVAP 891
Query: 547 IQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS----AVAMLNTPDGL 602
P + + + A LP Q P PAA + +PPS M TP
Sbjct: 892 -----PGVAALSIHSAVAQLPGQ----PVYPAAFPQMAPTDVPPSPHHTVQNMRATPP-- 940
Query: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ-APTPQAAAPPQA 661
QPA P P T+ P P PP + P P + PQ +PPQ PQ PPQ
Sbjct: 941 -QPALP--------PQPTLPPQPVLPPQPTLP-PQPVLPPQPTRPPQPVLPPQPMLPPQP 990
Query: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721
P P P L PE + P A P A T S + ++A+ P + VP +
Sbjct: 991 VLP-PQPALPVRPEPLQPHLPEQAAPAA--TPGSQILLGHPAPYAVDVAAQVPTVPVPPA 1047
Query: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
++S PP + PA P L PQ P S A+ + + Q P +++ P
Sbjct: 1048 AVLS-PPLPEVLLPAAP-----ELLPQFPSSLATVSASVQ-------SVPTQTATLLPPA 1094
Query: 782 QAPLGDSPHLPSPHPTRPPSRPPSRPQSVS--RPPSEP 817
PL P + SP PT + P + + S +PP P
Sbjct: 1095 NPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
Score = 61.6 bits (148), Expect = 6e-09
Identities = 86/319 (26%), Positives = 107/319 (33%), Gaps = 65/319 (20%)
Query: 627 APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP----------PQATTPQPSPGLASSPEK 676
+PP +ST LG + Q AP Q P A P P SSP
Sbjct: 1276 SPPHLST-CGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAP-ESSPPL 1333
Query: 677 IVLGQPPSATPTAILTQDSLQM-----FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
+ PP A+ + +D L FL SQQ LS GP + PP
Sbjct: 1334 PLSSLPPEASQDSAPYKDQLSSKEQPSFLA---SQQLLSQAGP-----------SNPPGA 1379
Query: 732 DPAPATPVAKGAGLGPQAPDSQA-SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH 790
PAP P + PQ + A S P P A+ GPG P G +
Sbjct: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPG----------TPQGLTSE 1429
Query: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
L + P P Q P L PC P P AS
Sbjct: 1430 LETSQPLAETHEAPLAVQ-----PLVVGLAPCTP------------------APEAASTR 1466
Query: 851 APTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
+AP P PP P+ P G PA P +AV + S +S+LP+P
Sbjct: 1467 DASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQ 1526
Query: 911 PPSQGPHKSPTPPPTLHLV 929
PPS PPP + V
Sbjct: 1527 PPSALESDGEGPPPRVGFV 1545
Score = 59.7 bits (143), Expect = 2e-08
Identities = 70/231 (30%), Positives = 88/231 (38%), Gaps = 33/231 (14%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTP--DGLVQPATPAAATGEAAPVLTVQPA 624
P PAP P ++ L +LPP A + + P D L P+ A+ L Q
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEA-SQDSAPYKDQLSSKEQPSFL---ASQQLLSQAG 1372
Query: 625 PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS----------P 674
P PP + P PL P PQ AAP +T P+P+ G AS
Sbjct: 1373 PSNPPG-APPAPLAPSSPPVTALPQ----DGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
Query: 675 EKIVLGQPPSATPTAILTQDSLQMFL------PQERSQQPLSAEGPHLSVPA---SVIVS 725
++ QP + T A L L + L P+ S + SA L PA S
Sbjct: 1428 SELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSG 1487
Query: 726 APPPA-QDPAPATPVAKGAG--LGPQAPDSQASPAPAPQIPAAAPLKGPGP 773
P PA PAP P A GA Q P P PQ P+A G GP
Sbjct: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGP 1538
Score = 55.1 bits (131), Expect = 5e-07
Identities = 66/238 (27%), Positives = 87/238 (36%), Gaps = 36/238 (15%)
Query: 789 PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848
P P P P S PP P S P + P + P Q L P S
Sbjct: 1317 PVAEHPAPEAPESSPPL-PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-S 1374
Query: 849 NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQL 908
NP PG P PL P S PP LP P +ST AS + + + P TP
Sbjct: 1375 NP----PGAPPAPLAPSS-PPVTALPQDGAAPATSTMPEPASGTASQAGGPG-TPQGLTS 1428
Query: 909 QFPPSQG---PHKSP-------------TPPPTLHLVPEPAAP----PPPPPRTFQMVTT 948
+ SQ H++P TP P + +AP PPP P T
Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
Query: 949 PFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP 1006
P PAL QP LL P+ + + A +P ++ P P +++ G+ P
Sbjct: 1489 PQPALGQPAPLL------PAAVGAVSLATSQLPSPPLGPTVPP--QPPSALESDGEGP 1538
Score = 55.1 bits (131), Expect = 5e-07
Identities = 57/196 (29%), Positives = 74/196 (37%), Gaps = 19/196 (9%)
Query: 251 QLLAKQVP---VSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVF 307
QL +K+ P S L S AGPS P A ++P + AA AT+
Sbjct: 1352 QLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPAS 1411
Query: 308 GGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLT 367
G A A P GTP GL S P H P +QP G+ P T
Sbjct: 1412 GTASQAGGP-GTPQ--------GLTSELETSQPLAETHEAPLAVQPLVVGLAP-----CT 1457
Query: 368 PKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQP 427
P P A + + EP P +P + T A ++ + A +L + P
Sbjct: 1458 PAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP 1517
Query: 428 PATTTGAAPPQPPGAL 443
P T PPQPP AL
Sbjct: 1518 PLGPT--VPPQPPSAL 1531
Score = 48.1 bits (113), Expect = 6e-05
Identities = 65/245 (26%), Positives = 84/245 (34%), Gaps = 48/245 (19%)
Query: 845 PPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLP-------PSSTSSAVASSSETSSR 897
P A +PAP AP PPL S PPE AP+ PS +S S S
Sbjct: 1317 PVAEHPAPEAP-ESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSN 1375
Query: 898 LPAPTPSDFQLQFPP-------SQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
P P+ PP P S P P + P P T ++ T+
Sbjct: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS-- 1433
Query: 951 PALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP 1010
QP L H+ P A L P T PA + A +
Sbjct: 1434 ----QP---LAETHEAPL------------AVQPLVVGLAPCT-PAPEAASTRDASAPRE 1473
Query: 1011 TAPSHAPAPAPMAATGLP------PLLPAENKAFA---SNLPTLNVAKAASSGPGKPSGL 1061
P AP P+P + T P PLLPA A + S LP+ + P PS L
Sbjct: 1474 PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVP--PQPPSAL 1531
Query: 1062 QYESK 1066
+ + +
Sbjct: 1532 ESDGE 1536
Score = 45.8 bits (107), Expect = 3e-04
Identities = 110/463 (23%), Positives = 153/463 (33%), Gaps = 64/463 (13%)
Query: 523 PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALF--QMPVSLAAGSLPTQSQPAPAGPAA- 579
PLS P A A LS+ QP+ Q +S A S P + PAP P++
Sbjct: 1334 PLSSLPPEASQDSAPYKDQLSSKE----QPSFLASQQLLSQAGPSNPPGAPPAPLAPSSP 1389
Query: 580 -TTVLQGVTLPPSAVAMLNTPDGLVQ----PATPAAATGEAAPVLTVQPAPQAPPAVSTP 634
T L P+ M G P TP T E + +AP AV P
Sbjct: 1390 PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQ-P 1448
Query: 635 LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLA--SSPEKIVLGQPPSATPTAILT 692
L +GL P+A + + A+ P+ P P+P + S + LGQP P A+
Sbjct: 1449 LVVGLAP--CTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGA 1506
Query: 693 QDSLQMFLPQERSQQPLSAEGPHLSVPASVIVS---APPPAQDPAPATPVAKGAGL---- 745
LP PL P P S + S PPP +T + L
Sbjct: 1507 VSLATSQLP----SPPLGPTVP--PQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
Query: 746 -GPQAPDSQASPAPAPQIP----AAAPLKGPGPSSS--------PSLPHQAPLGDSPHLP 792
P S AS ++ PL+G P S P +P +A G LP
Sbjct: 1561 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSG-RVQLP 1619
Query: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP-PASNPA 851
P + P S P G V + VP P PA
Sbjct: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679
Query: 852 PTAPGPPQPPLRPQSQPPEGPLPPAP----------HLPPSSTSSAVASSSETSSR---- 897
P +P R + E P P P + + A+ S + +
Sbjct: 1680 FVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVS 1739
Query: 898 LPAPTPSDFQLQFPPSQGPHKSP-----TPPPTLHLVPEPAAP 935
PA T F + + SP + PP ++L P++P
Sbjct: 1740 SPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSP 1782
Score = 40.8 bits (94), Expect = 0.010
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 1326 ALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPP----PAAPERKPLGTAPH 1381
AL P PP P PP+P PP PT PP P P P P
Sbjct: 943 ALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT--------RPPQPVLPPQPMLPPQPVLPP 994
Query: 1382 CPRLPLR-KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKV 1421
P LP+R + + ++ AP TP + G PAP V
Sbjct: 995 QPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDV 1035
Score = 36.2 bits (82), Expect = 0.25
Identities = 45/186 (24%), Positives = 68/186 (36%), Gaps = 22/186 (11%)
Query: 901 PTPSDFQLQFPPSQG---PHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957
P P Q+ + G P + P HL+P P P T + F + Q
Sbjct: 568 PVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP----PTLPTSATSLASDSTFDS-GQGS 622
Query: 958 ALLERFHQVPSGIILQNKAGGAPAAPQT----STSLGPLTSPAASVLVSGQAPSGTPTAP 1013
+ ++L + A AP+ Q S GP+ + L + Q P+ P P
Sbjct: 623 TVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLP 682
Query: 1014 SHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKP 1073
+ PAP L P +FA LP + +GPG+P+ G + P
Sbjct: 683 VGS-VPAPACPPSLQQHFPDPAMSFAPVLPP--PSTPMPTGPGQPAP-------PGQQPP 732
Query: 1074 PTLQPS 1079
P QP+
Sbjct: 733 PLAQPT 738
Score = 35.4 bits (80), Expect = 0.43
Identities = 44/143 (30%), Positives = 57/143 (39%), Gaps = 35/143 (24%)
Query: 930 PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
P P AP PP P +LP P+A + AP Q S+
Sbjct: 1322 PAPEAPESSPP-------LPLSSLP-PEASQD----------------SAPYKDQLSSKE 1357
Query: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLP-PLLPAENKAFASNL---PTL 1045
P + A+ L+S PS P AP PAP+A + P LP + A A++ P
Sbjct: 1358 QP-SFLASQQLLSQAGPSNPPGAP-----PAPLAPSSPPVTALPQDGAAPATSTMPEPAS 1411
Query: 1046 NVAKAASSGPGKPSGLQYESKLS 1068
A A GPG P GL E + S
Sbjct: 1412 GTASQA-GGPGTPQGLTSELETS 1433
Score = 35.0 bits (79), Expect = 0.57
Identities = 52/204 (25%), Positives = 70/204 (34%), Gaps = 22/204 (10%)
Query: 1329 PVHQPPPPPATLK-VAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPL 1387
P PP P T++ + PP+P PP PT P P P T P P LP
Sbjct: 921 PTDVPPSPHHTVQNMRATPPQPALPPQPT----------LPPQPVLPPQPTLPPQPVLPP 970
Query: 1388 RKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
+ T P P P PA LP + + L + A Q +L P
Sbjct: 971 QPTRPPQPVLPPQPM-LPPQPVLPPQPA-LPVRPEPLQPHLPEQAAPAATPGSQILLGHP 1028
Query: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDS 1507
P AAQ P +PPA P+V + PQ + + +++ S
Sbjct: 1029 APYAVDVAAQVPTVP------VPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQS 1082
Query: 1508 ILNLQQA---PGRTPAPSYPHAAS 1528
+ P P P P AS
Sbjct: 1083 VPTQTATLLPPANPPLPGGPGIAS 1106
Score = 34.3 bits (77), Expect = 0.97
Identities = 86/402 (21%), Positives = 126/402 (31%), Gaps = 45/402 (11%)
Query: 1176 DRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGAS 1235
D++ +E+ + LA + L++ P S G P A + P +AP S
Sbjct: 1351 DQLSSKEQPSFLASQQLLSQAGP------SNPPGAPPAPLAPSSPPVTALPQDGAAPATS 1404
Query: 1236 TQPPPHLPTKLVIRHGGAGGSPSVTWA-RASSSLSSSSSSSSAASSLDADEDGPMPSRNR 1294
T P P T + GG G +T S L+ + + A L G P
Sbjct: 1405 TMPEPASGT--ASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVV---GLAPCTPA 1459
Query: 1295 PPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPP---------PPATLKVAEP 1345
P + R + + A T + QP P AT ++ P
Sbjct: 1460 P--EAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP 1517
Query: 1346 PPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP 1405
P P PP P + + PPP T Y+E+V A GTP
Sbjct: 1518 PLGPTVPPQPPSALESDGEGPPPRVGFVD--STIKSLDEKLRTLLYQEHVPTSSASAGTP 1575
Query: 1406 A---------GRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAA 1456
RG P D A + +E + +L Q +++ P A
Sbjct: 1576 VEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAV 1635
Query: 1457 QGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPG 1516
G P R D D +SDS H+ ++ + P
Sbjct: 1636 MEQGTSSSMTAESSP---RSMLGYDRDGRQVASDS--------HVVPSVPQDVPAFVRPA 1684
Query: 1517 RTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTL 1558
R + + A PPP +SH LGAR L
Sbjct: 1685 RVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARAL 1726
Score = 33.9 bits (76), Expect = 1.3
Identities = 66/267 (24%), Positives = 91/267 (34%), Gaps = 45/267 (16%)
Query: 1226 PLSSSAPGASTQPPPHL--------PTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSA 1277
PLSS P AS P+ P+ L + + PS + L+ SS +A
Sbjct: 1334 PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTA 1393
Query: 1278 ASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGL-SKVVHNTALDPVHQPPPP 1336
+DG P+ + P S+ G GL S++ + L H+ P
Sbjct: 1394 LP-----QDGAAPATSTMPEPASGTASQAGGP---GTPQGLTSELETSQPLAETHEAPLA 1445
Query: 1337 PATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPH------CPRLP---- 1386
L V P P P T + + PP APE P P P LP
Sbjct: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
Query: 1387 ----LRKTYRENVGGPGAPEGTPAG-RARGGSPAPLPAKVDEATSGLIRELAAVEDELYQ 1441
GP P P+ + G P P VD L +L + LYQ
Sbjct: 1506 AVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTL---LYQ 1562
Query: 1442 RMLKGPPPEPAASAAQGT----GDPDW 1464
+ P +SA+ GT GD D+
Sbjct: 1563 EHV------PTSSASAGTPVEVGDRDF 1583
Score = 33.5 bits (75), Expect = 1.6
Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 923 PPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPA- 981
PP L P PP P + ++ L +A P+ ++ Q A GAPA
Sbjct: 54 PPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPAD 113
Query: 982 -APQTSTSLGPLTSPAASVLVSGQAPSGTP 1010
P+ + P P A+ + + AP G P
Sbjct: 114 AGPEPVGTQEPGPDPIAAAVETAPAPDGGP 143
Score = 33.5 bits (75), Expect = 1.6
Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 13/65 (20%)
Query: 604 QPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT 663
+PA PA A L QP PA + P P+G Q+P P P AAA A
Sbjct: 92 RPAAPAPAA------LVAQPGAPGAPADAGPEPVGTQEP-------GPDPIAAAVETAPA 138
Query: 664 PQPSP 668
P P
Sbjct: 139 PDGGP 143
Score = 33.5 bits (75), Expect = 1.6
Identities = 93/396 (23%), Positives = 135/396 (34%), Gaps = 79/396 (19%)
Query: 1205 SRSLGLPIAASSEGHRLPGH-GPLSSSAPGASTQP-PPHLPTKLVIRHGGA---GGSPSV 1259
+R +P+ H G GP P A PP LPT + G S
Sbjct: 564 ARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGST 623
Query: 1260 TWARASSSLSSSSSSSSAASSLDADE--------DGPMPSRNRPPIKTYEARSRI-GLKL 1310
++ + SS S S A ++ + +GP+ ++ P + Y+ + GL +
Sbjct: 624 VYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPV 683
Query: 1311 KIKQEAGLSKVVHNTALDPVHQPPP---PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPP 1367
+ DP P PP+T P P P P P GQ PP
Sbjct: 684 GSVPAPACPPSLQQHFPDPAMSFAPVLPPPST-----PMPTGPGQPAPPGQ-----QPPP 733
Query: 1368 PAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP--AGRARGGSPAPL-PAKVDEA 1424
A P P AP P +PL+ P P P A ++ G+PA L P ++ +A
Sbjct: 734 LAQPTPLPQVLAPQ-PVVPLQ---------PVPPHLPPYLAPASQVGAPAQLKPLQMPQA 783
Query: 1425 TSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQ 1484
++ LA V ++ + P A PD +PP + SP V
Sbjct: 784 P---LQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
Query: 1485 ASFSSDSPQDDTLTEHLQSAIDSILNLQQAPG-------RTPAPSYP------------- 1524
S ++ P LQ+ + L PG RT P+ P
Sbjct: 841 PSLAAPLPPASPALP-LQA-----VKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV 894
Query: 1525 -----HAASAGTPASPP-----PLHRPEAYPPSSHN 1550
H+A A P P P P PPS H+
Sbjct: 895 AALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHH 930
Score = 31.6 bits (70), Expect = 6.3
Identities = 54/211 (25%), Positives = 73/211 (34%), Gaps = 42/211 (19%)
Query: 1342 VAE-PPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGA 1400
VAE P P P PP + + +AP + L + L ++ + GP
Sbjct: 1318 VAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQ--AGPSN 1375
Query: 1401 PEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTG 1460
P G P PAPL T+ L ++ AA PEPA+ A G
Sbjct: 1376 PPGAP--------PAPLAPSSPPVTA-LPQDGAAPATSTM--------PEPASGTASQAG 1418
Query: 1461 DPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPA 1520
PG P + E+ Q T A+ ++ + AP TPA
Sbjct: 1419 -----GPGTPQGLTSELETS------------QPLAETHEAPLAVQPLV-VGLAPC-TPA 1459
Query: 1521 PSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
P A P P P PE PS H+G
Sbjct: 1460 PEAASTRDASAPREPLPPPAPE---PSPHSG 1487
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 117 bits (292), Expect = 1e-25
Identities = 256/1049 (24%), Positives = 355/1049 (33%), Gaps = 213/1049 (20%)
Query: 560 SLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSA--VAMLNTPDG----LVQPATPAAATG 613
S+A P S+ +P P T T P A VA P G +QP P
Sbjct: 360 SVAEQHTPVCSRFSPPEPGDTP-----TDEPDALYVACQGQPKGGHVTSMQPKEPGPLQC 414
Query: 614 EAAPV--LTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLA 671
EA P+ VQ PQ ++ +PL PP +P + P ++ T P
Sbjct: 415 EAKPLGKAGVQLEPQLEAPLNEEMPL--------LPPPEESPLSPPPEESPTSPP----- 461
Query: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
PE L PP P + L + +L + P E S LS P +PPP
Sbjct: 462 --PEASRLSPPPEELPASPLPE-ALHLSRPLEESP---------LSPPPEESPLSPPP-- 507
Query: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+ +P +P+ + P +P ++ P+PA + P + P P +SP P P +SP
Sbjct: 508 ESSPFSPLEES----PLSPPEESPPSPALETPLSPP-----PEASPLSP---PFEESPL- 554
Query: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP---PPQAPPTLPGIFVIQNQLGVPPPAS 848
SP P P+ PP +S PP E P+ P P P PP +F P
Sbjct: 555 -SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF----------PPF 603
Query: 849 NPAPTAPGPPQPPLRPQ------SQPPE-GPLPPAPHLPPSSTSSAVASSSETS--SRLP 899
+P +P P + PL P S PPE P+ P P P S V+ S SRL
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL- 662
Query: 900 APTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL 959
+P P + L PP + P P L PE + PPP + PA P P+
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS--------PASPPPEDS 714
Query: 960 LERFHQVPSGIILQNKAGGAPAAPQTST-SLGPLTSPAASVLVSGQAPSGTPTAPSHAPA 1018
L S ++ P PQ S GP SP P P +P
Sbjct: 715 LMSLPLEESPLL------PLPEEPQLCPRSEGPHLSPR-------------PEEPHLSPR 755
Query: 1019 P-----APMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPG---KPSGLQY-----ES 1065
P +P A P L P + +P + GP +P L E
Sbjct: 756 PEEPHLSPQAEE--PHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 1066 KLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQ--GA 1123
LS + + P L P E L + P+ P E P + G
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 1124 LPSPSDYHKVDEEFETVSTQLL-KRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQE 1182
P+P + E + LL + + + L L E +SPS E + ++ +
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL-MPP 932
Query: 1183 EKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHL 1242
+ L + P +S L P A + PL++ PPP
Sbjct: 933 DPLPPPLSPIITAAAPPA-LSPLGELEYPFGAKGDSDP---ESPLAAPILETPISPPPEA 988
Query: 1243 ------PTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPP 1296
P +I G L S S + + S P
Sbjct: 989 NCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP 1048
Query: 1297 IKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPT 1356
+ S IG + + EA L H + V +P P A P P P P
Sbjct: 1049 LSVPSPLSPIGKVVGVSDEAEL----HEMETEKVSEPECP------ALEPSATSPLPSPM 1098
Query: 1357 GQMNGTVDHPPPAAPERKPLG--TAPHCPRLPLRKTYRENVGGPGA---PEGTPAGRAR- 1410
G ++ P PA + LG TAP + + PG+ P TP A
Sbjct: 1099 GDLSCPAPSPAPALDDFSGLGEDTAP-----------LDGIDAPGSQPEPGQTPGSLASE 1147
Query: 1411 -GGSPAPLPAKVDEATSGLIRELAAVED-ELYQRMLKGPPPEPAASAAQGTGDPDWEAPG 1468
GSP L + ELA V E+Y PE +A QG+ + E P
Sbjct: 1148 LKGSPVLLDPE----------ELAPVTPMEVY--------PECKQTAGQGSPCEEQEEPR 1189
Query: 1469 LPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAAS 1528
P A P TL + ++ I NL Q AS
Sbjct: 1190 APVA-------------------PTPPTLIK--SDIVNEISNLSQGD-----------AS 1217
Query: 1529 AGTPASPPPLHRPEAYPPSSHNGGLGART 1557
A P S P L P+ S + LG T
Sbjct: 1218 ASFPGSEPLLGSPDPEGGGSLSMELGVST 1246
Score = 114 bits (286), Expect = 6e-25
Identities = 203/839 (24%), Positives = 287/839 (34%), Gaps = 121/839 (14%)
Query: 320 PSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLT 379
P PL+ P SP P P R P + PA LP L+ P +P
Sbjct: 444 PEESPLSPPPE--ESPTSPPPEA--SRLSPPPEELPASPLPEALHLSRPLEESP------ 493
Query: 380 IQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQP 439
+ P P P P++ F ++ + P+PAL+ + PP + +PP
Sbjct: 494 LSPPPEESPLSPP-PESSPFSPLEESPLSPPEESPPSPALETPL--SPPPEASPLSPPFE 550
Query: 440 PGALSKP---MSVHLLNQGSSIVIPAQHML---PGQNQFLLPGAPAVQLPQQLSALPANV 493
LS P + + S + P + P + + P A +L P +
Sbjct: 551 ESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610
Query: 494 GGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVG-QP 552
+ + P +L P P+S P +P S LS P+ P
Sbjct: 611 PPEESPLSPPPEASRLSPPPE------DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 553 ALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT 612
+ P+S PT S P A + T PP + + P + P
Sbjct: 665 PPEESPLSPPPEESPT-SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL--- 720
Query: 613 GEAAPVLTVQPAPQAPPAVSTP-LPLGLQQPQAQQPPQAP--TPQAAAPPQATTPQPSPG 669
E +P+L + PQ P P L ++P P+ P +PQA P + P+ P
Sbjct: 721 -EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE-EPC 778
Query: 670 LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS-VPASVIVSAPP 728
L + PE+ P +P A S Q P+E P + E PHLS VP +S P
Sbjct: 779 LCAVPEE------PHLSPQAEGPHLSPQ---PEELHLSPQTEE-PHLSPVPEEPCLSPQP 828
Query: 729 PAQDPAPATPVAKGAGLGPQAPDSQASP-------APAPQIPAAAPLKGPGPSSSPSLPH 781
+ + +P ++ L P+ +S SP +P P+ P P + P P P P
Sbjct: 829 ---EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Query: 782 Q-----APL---------GDSPHLPSPH--PTRPPSRPPSRPQSVSRPPSEPPLHPCPPP 825
+PL G+ P P P P P P PQ + P PPL P
Sbjct: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945
Query: 826 QAPPTLPGIFVIQNQLGV----PPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPP 881
APP L + ++ G P + AP P PP PE P+PP LPP
Sbjct: 946 AAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPE-PVPPM-ILPP 1003
Query: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP------ 935
S S +S LP Q P P +PP VP P +P
Sbjct: 1004 SPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG 1063
Query: 936 ----------------PPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGA 979
P P T+P P+ P G + A
Sbjct: 1064 VSDEAELHEMETEKVSEPECPALEPSATSPLPS--------------PMGDLSCPAPSPA 1109
Query: 980 PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFA 1039
PA S LG T+P + G P P P G P LL E A
Sbjct: 1110 PALDDFS-GLGEDTAPLDGIDAPGSQPE-----PGQTPGSLASELKGSPVLLDPEELAPV 1163
Query: 1040 SNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHP 1098
+ + K ++G G P Q E + PPTL S + +L + S P
Sbjct: 1164 TPMEVYPECK-QTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFP 1221
Score = 92.4 bits (228), Expect = 3e-18
Identities = 148/615 (24%), Positives = 207/615 (33%), Gaps = 143/615 (23%)
Query: 573 APAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVS 632
+P AA T+ G P+ ++ + DG ++P + ++ L ++ PQ P V
Sbjct: 2115 SPPPAAAPTIFIGSPTTPAGLS--TSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP 2172
Query: 633 TPLPLGL-----------QQPQAQQPPQAPTPQAAAPPQA---------------TTPQP 666
+ P GL P P +PT A PP TTP
Sbjct: 2173 SQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG 2232
Query: 667 SP-GLASSPEKIVLGQPPSATPTAILT-------QDSLQMFLPQ---------ERSQQPL 709
+P S+P+ + + PS A+ + S + P E ++ L
Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292
Query: 710 SAEGPHLSVPASVIVSAP------------PPAQDPAPATPVAK-------GAGLGPQAP 750
A P P V +P P AP TP A G GL PQ P
Sbjct: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP 2352
Query: 751 DSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPH----------PTRPP 800
+ AP+P P+ + PG + P Q PL P P P P+ P
Sbjct: 2353 PPAQALAPSP--PSHPDIFRPGSYTDPYA--QPPLTPRPQPPPPESCCALPPRSLPSDPF 2408
Query: 801 SRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGP-PQ 859
SR P+ PQS S S+ PL P P + + P P + P +P P +
Sbjct: 2409 SRVPASPQSQS--SSQSPLTPRP-------------LSAEAFCPSPVT-PRFQSPDPYSR 2452
Query: 860 PPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS-------SRLPAPTPSDFQLQFPP 912
PP RPQS+ P PL P P + S + TS + LPA + + P
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512
Query: 913 SQGPH--KSP-------TPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERF 963
Q P+ +SP TP P P+ P P P P LP P + F
Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP------PVPQPGLPPPHGINSHF 2566
Query: 964 HQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
P +LG S +V PSG+P PS
Sbjct: 2567 GPGP--------------------TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606
Query: 1024 ATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKP------SGLQYESKLSGLKKPPTLQ 1077
+ L P A +LP L+ + SG P G S L+ + P T
Sbjct: 2607 LSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQD 2666
Query: 1078 PSKEACFLEHLHKHQ 1092
P L K +
Sbjct: 2667 PGMSGLSQTELEKQR 2681
Score = 92.4 bits (228), Expect = 3e-18
Identities = 132/454 (29%), Positives = 178/454 (39%), Gaps = 63/454 (13%)
Query: 451 LLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLI 510
LLNQ +++ P Q Q L PG PA P Q + P +G +L Q
Sbjct: 3977 LLNQSRTLLSPQQQQQ--QQVALGPGMPAK--PLQHFSSPGALGPTLLLTGKE----QNT 4028
Query: 511 ANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS 570
+P ++++ GP + H G A I + +P + +S + L Q
Sbjct: 4029 VDPAVSSEATEGP-------STHQGGPLA-IGTTPESMATEPGEVKPSLSGDSQLLLVQP 4080
Query: 571 QPAPAGPAATTVLQGVTLP---PSAVAMLNTPDGLVQPATPAAATGEAA--PVLTVQPAP 625
QP P P++ + + LP V++L+T G + ++ EA+ P L QP+
Sbjct: 4081 QPQPQ-PSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139
Query: 626 QA--PPAVSTPLPLGLQQPQAQQPPQAPT-PQAAAP-PQATTPQPSPGLASSPEKIVLGQ 681
P T LG QQP ++P Q T PQ P P + Q PG+ P +GQ
Sbjct: 4140 SLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMP---TVGQ 4196
Query: 682 PPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAK 741
+ + L+ PQ+ QQ L A + S V PP Q+P T +
Sbjct: 4197 LRAQLQGVLAKNPQLRHLSPQQ--QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ 4254
Query: 742 GAGLGPQAPDSQASPAPAPQIPAAAPL-KGPGPSSSPSLPHQ-APLGDSPHLPSPHPTRP 799
G LG Q Q P PQ L GP P P LP L P L HPT P
Sbjct: 4255 GL-LGCQP---QLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP 4310
Query: 800 PSRP--PSRPQSVSRPPSE-------PPLHPCPPPQAPPTL---PGIFVIQNQLGVPPPA 847
PS P P RP + P S+ PP HP P PTL PG V P A
Sbjct: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG--------RVSPAA 4362
Query: 848 SNPAPT----APGPPQPP--LRPQSQPPEGPLPP 875
+ A T GP PP L +P + L P
Sbjct: 4363 AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVP 4396
Score = 73.2 bits (178), Expect = 2e-12
Identities = 201/862 (23%), Positives = 296/862 (34%), Gaps = 185/862 (21%)
Query: 128 PFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDV 187
P+ PT PA P G ++ AG F + PP HQ P
Sbjct: 2198 PYPSPTGAPAQ----PPMLGASSRPGAGQPGEFHTT--------PPGTPRHQPSTP---- 2241
Query: 188 VNKALSVQPFLQP--VGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMAL 245
PFL+P L N+ + PG+ G G A+ L P G+ AL
Sbjct: 2242 -------DPFLKPRCPSLDNLAVPESPGVGG------GKASEPLLSPPPF---GESRKAL 2285
Query: 246 NTPTSQLLAKQV----PVSGYLASAAGPSE--------------PVTLASAGVSPQGAGL 287
+L A P G++ S + + P+T ++ V PQ GL
Sbjct: 2286 EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGL 2345
Query: 288 VIQKNL---SAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPA---PN 341
++ + A+A + + G+ + P P P P S +P P+
Sbjct: 2346 GLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPS 2405
Query: 342 VILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQG-----EPGALPQ------- 389
R P Q + + P L+ + F P+ T Q P + PQ
Sbjct: 2406 DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP 2465
Query: 390 --QPKAPQ--NLTFMAAGKAGQNVVLSGFPA--------------PALQANVFKQPPATT 431
+P PQ + F A A ++ GFPA P+ Q F + P T
Sbjct: 2466 LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTG 2525
Query: 432 TGAAPPQP-----PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQL 486
P P P A+ +P + Q +P H G N PG P + PQ
Sbjct: 2526 AFVGTPSPMRFTFPQAVGEPSLKPPVPQPG---LPPPH---GINSHFGPG-PTLGKPQST 2578
Query: 487 SALPA----NVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG--PVLAPHSGAHSAH 540
+ A + G L ++ TG +P+ L P G P L+ H + +
Sbjct: 2579 NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLS-HGASQRSG 2637
Query: 541 ILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTV---LQGVTLPPSAVAMLN 597
I S P++ + M SLA LP P +G + T + Q L +
Sbjct: 2638 ITS--PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQI 2695
Query: 598 TPDGLVQPA-TPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA 656
+ L Q T AAA G P + P +P +Q Q P A T +
Sbjct: 2696 QRNTLRQEKETAAAAAGAVGPPGSWGAEPSSP---------AFEQLSRGQTPFAGTQDKS 2746
Query: 657 A-----PPQATTPQPSPGLASSPEKIVLGQPPSATPTAI------LTQDSLQMF------ 699
+ P + + P PG S +++ PP ATP+++ L S +
Sbjct: 2747 SLVGLPPSKLSGPILGPGSFPSDDRLSR-PPPPATPSSMDVNSRQLVGGSQAFYQRAPYP 2805
Query: 700 --LPQERSQQPL-------SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAP 750
LP ++ QQ L +A ++ A + P A +P+A G+ + P
Sbjct: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLA---GISTRLP 2862
Query: 751 DSQASPAPAPQIPA----------------AAPLKGPGPSSSPSLPHQAPLGDSPHLPSP 794
P P P PA P G GP P P P+ + PH +P
Sbjct: 2863 -GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGP---PQRPRFYPVSEDPHRLAP 2918
Query: 795 HPTRP---PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
R PP +P + P LHP P + PTLP + N+ PP+S
Sbjct: 2919 EGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKG-PTLPTGLELVNR----PPSS--- 2970
Query: 852 PTAPGPPQP-PLRPQSQPPEGP 872
T G P P L P E P
Sbjct: 2971 -TELGRPNPLALEAGKLPCEDP 2991
Score = 65.9 bits (159), Expect = 3e-10
Identities = 185/808 (22%), Positives = 259/808 (32%), Gaps = 153/808 (18%)
Query: 314 SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAP 373
+ P GTP QP P L P P+ L P P G + L+P PF
Sbjct: 2228 TTPPGTPRHQPSTPDPFL--KPRCPS----LDNLAVPESPGVGGGKASEPL-LSPPPFGE 2280
Query: 374 AGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNV------VLSGFPAPALQANVFKQP 427
+ L ++ E P NL F+ + +G ++ F AP +P
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340
Query: 428 PATTTGAAPPQPPGAL----SKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLP 483
+ G P +PP A S P + GS AQ L + Q P + P
Sbjct: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
Query: 484 QQL-----SALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS 538
+ L S +PA+ Q ++ +P T L A + S P P S S
Sbjct: 2401 RSLPSDPFSRVPASPQSQS-SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS 2459
Query: 539 AHILSAA-------PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS 591
+ P +V A SL AG P PAG V G
Sbjct: 2460 RDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG------ 2513
Query: 592 AVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL-GLQQPQAQQPPQA 650
P V+ A G +P+ P P++ P+P GL P
Sbjct: 2514 ------QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567
Query: 651 PTPQAAAP-------------PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQ 697
P P P P + PS G + +PPS P D
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPP--APDGSL 2625
Query: 698 MFLPQERSQQ-----PLSA-EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPD 751
+L SQ+ P+ E P + +S+ + P QDP + GL +
Sbjct: 2626 PYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMS-------GLSQTELE 2678
Query: 752 SQASPAPAPQI----------------PAAAPLKGPGPSSS----PSLP--HQAPLGDSP 789
Q ++ AAA GP S PS P Q G +P
Sbjct: 2679 KQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTP 2738
Query: 790 HLPSPHPTRPPSRPPSRPQSVSRP-------PSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
+ + PPS+ +S P PS+ L PPP P ++ V QL
Sbjct: 2739 FAGTQDKSSLVGLPPSK---LSGPILGPGSFPSDDRLSRPPPPATPSSMD---VNSRQLV 2792
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP------------------PEGPLPPAPHLPPSST 884
A AP P PL+ Q Q P P P L +
Sbjct: 2793 GGSQAFYQR--APYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQAL 2850
Query: 885 SSAVASSSETSSRLPAPT--------PSDF-QLQFPPSQGPHKSPTPPPTLHLVPEPAAP 935
S +A S+RLP P P+ F +L+ +G TP P
Sbjct: 2851 GSPLAG---ISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTP--------FPGQG 2899
Query: 936 PPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP 995
PP PR + + P P+ L SG+ Q + AP AP+ + SL P
Sbjct: 2900 PPQRPRFYPVSEDPHRLAPEGLRGL-----AVSGLPPQKPS--APPAPELNNSLHPTPHT 2952
Query: 996 AASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
L +G P + + P P+A
Sbjct: 2953 KGPTLPTGLELVNRPPSSTELGRPNPLA 2980
Score = 63.5 bits (153), Expect = 1e-09
Identities = 137/544 (25%), Positives = 195/544 (35%), Gaps = 103/544 (18%)
Query: 605 PATPA---AATGEAAPVLTVQPAPQ--APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659
PA P ++ G P L + Q PAVS+ G Q TP++
Sbjct: 4002 PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPES---- 4057
Query: 660 QATTP-QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL-------SA 711
AT P + P L+ + +++ P P+++ Q L+ LP ++ QQ +
Sbjct: 4058 MATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLR--LPGQQQQQVSLLHTAGGGS 4115
Query: 712 EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG----LGPQAP----DSQASPAPAPQIP 763
G S +S S P P+ + G+ LGPQ P Q + P P P
Sbjct: 4116 HGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKP 4175
Query: 764 AAAPLKG---PGPSSSPSLPH-----QAPLGDSPHLPSPHPTRPPSRPP---SRPQSVSR 812
G PG P++ Q L +P L P + R S+
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235
Query: 813 PPSEPPLHPCPPPQAPPTLPGIFVIQNQLG-VPPPASNP------APTAPGPPQPPLRP- 864
+ P + P Q P L G+ Q QLG P P + P P GPP+ P P
Sbjct: 4236 AVRQTPPYQEPGTQTSP-LQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPG 4294
Query: 865 --QSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPT---PSDFQLQFPPSQGPHKS 919
+ P GP+ P P PPSS + S+LP+P+ P++ QL
Sbjct: 4295 ALSTGPVLGPVHPTP--PPSS-----PQEPKRPSQLPSPSSQLPTEAQL----------- 4336
Query: 920 PTPPPTLHLVPEPAAP---PPP---PPRTFQMVTTPFP----ALPQPKALLERFHQVPSG 969
PPT P+P P PPP P Q+ T F P L E S
Sbjct: 4337 ---PPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSS 4393
Query: 970 IIL----QNKAGGAPAAPQTSTSLGPLTSPAA--SVLVSGQA---PSGTPTAPSHAPAPA 1020
++ Q P A Q S P P A + V +A P G P +H
Sbjct: 4394 LVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAG 4453
Query: 1021 PMAATG---LPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQ 1077
P + G L LL A+N ++ S G +SKL+GL++
Sbjct: 4454 PRSEAGHLLLQKLLRAKNVQLSTG--------RGSEGLRAEINGHIDSKLAGLEQKLQGT 4505
Query: 1078 PSKE 1081
PS +
Sbjct: 4506 PSNK 4509
Score = 59.3 bits (142), Expect = 3e-08
Identities = 94/372 (25%), Positives = 125/372 (33%), Gaps = 65/372 (17%)
Query: 613 GEAAPVLTVQPAPQAPPAVSTPLPLG---LQQPQAQQPPQAPTPQAAAPPQATTPQPSPG 669
G P L P P + LPLG P P +P + + P PG
Sbjct: 1908 GCGTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPG 1967
Query: 670 LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ--PLSAEGPHLSVPASVI---V 724
SP G PS TPT T+ +RS Q E LS + V+ +
Sbjct: 1968 EPDSPWTGSGGTTPS-TPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANI 2026
Query: 725 SAPPPAQD-PAPATPVAKGAGLGPQAPDSQASP--APAPQIPAAAPLKGPGPSSSPSLPH 781
+ P QD P ++ + L + P + +P A AA + + +
Sbjct: 2027 NFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINK 2086
Query: 782 QAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTL--------PG 833
Q +GD +R RP R P +P PPP A PT+ G
Sbjct: 2087 QTKVGDI------------ARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAG 2134
Query: 834 IFVIQNQLGVPPPASNPAPTAPG------PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSA 887
+ + PP S P P +PG PPQ P + SQ P G P P P
Sbjct: 2135 LSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEP------- 2187
Query: 888 VASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP------PPPR 941
R P P+ +PP P +P PP L P A P PP
Sbjct: 2188 ---------RFPTAPPT-----YPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGT 2233
Query: 942 TFQMVTTPFPAL 953
+TP P L
Sbjct: 2234 PRHQPSTPDPFL 2245
Score = 53.9 bits (128), Expect = 1e-06
Identities = 213/968 (22%), Positives = 303/968 (31%), Gaps = 245/968 (25%)
Query: 130 QLPTLQPADGGA-GPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVV 188
Q+ L A GG+ G G+G ++ ++ P L S + L P +T L P Q ++
Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPS---VSLGDQPGSMTQNLLGPQQPML 4160
Query: 189 NKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTP 248
+ + QP +P P LQ G PG T+G Q+ G V+A N
Sbjct: 4161 ERPMQNNTGPQPP-------KPGPVLQS-GQGLPGVGIMPTVGQLRAQLQG--VLAKNPQ 4210
Query: 249 TSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFG 308
L +Q Q L++Q+ L + A
Sbjct: 4211 LRHLSPQQ------------------------QQQLQALLMQRQLQQSQAVR-------- 4238
Query: 309 GAGAASAPTGTPSGQPLAVAPGLGSSPLV---PAPNVILHRTPTPIQPKPAGVLPPKLYQ 365
+ P P Q + LG P + P P P+Q AG P Q
Sbjct: 4239 ----QTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQT------GPLQELGAGPRP----Q 4284
Query: 366 LTPKPFAPAGATLT--IQGE-----PGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPA 418
P+ AP GA T + G P + PQ+PK P L P+P+
Sbjct: 4285 GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL-----------------PSPS 4327
Query: 419 LQANVFKQPPATTTGAAPPQ------PPGALSKP---MSVHLLNQGSSIVIPAQHM---- 465
Q Q P T G PQ PPG +S ++ L ++G P ++
Sbjct: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
Query: 466 -------LPGQ----NQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPI 514
+PG N ++P A + + Q+ P +G Q + A G+ I P
Sbjct: 4388 KPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREA---NGEPIGAPG 4444
Query: 515 LTNQNL-AGPLSLGPVLAPHSGAHSAHI-LSAAPIQVGQPALFQMPVSLAAGSLPTQSQP 572
+N L AGP S L + ++ LS G A + L + Q
Sbjct: 4445 TSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQG 4504
Query: 573 APAGPAATTVLQGVTLPPSAVAM-----------LNTPDG-------------------L 602
P+ + +T P V L DG L
Sbjct: 4505 TPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPL 4564
Query: 603 VQPATPA-----AATGEAAPVLTVQPAPQAPPAVSTPLPLG-------LQQPQAQQPPQA 650
+PA A A G PV A S LP G L + PP
Sbjct: 4565 TEPAITANFSLFAPFGSGCPVNGQSQLRGA--FGSGALPTGPDYYSQLLTKNNLSNPPTP 4622
Query: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQ------------- 697
P+ PP + + G+ S E LG+ P +A ++ +L+
Sbjct: 4623 PSSLPPTPPPSVQQKMVNGVTPSEE---LGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
Query: 698 MFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA 757
+ P + + E S IV A P P G G + +A
Sbjct: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739
Query: 758 PAPQIPAAAPLKGPGPSSSPSLPHQAPLGD-SPHLPSPHPTRPPSRPPSRPQSVSRPPSE 816
P IP A S P P P G +P P + SV S
Sbjct: 4740 VIPLIPRA---------SIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSA 4790
Query: 817 PPLHPCPPPQAPPTLPGIFV-IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGP--- 872
A L G+ V + L + P S P + P+ EGP
Sbjct: 4791 A---------AAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGK 4841
Query: 873 ----------------------LP------------------PAPHLPPSSTSSAVASSS 892
LP PAP PP+ S S+
Sbjct: 4842 EKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPE-PPTQHSYTYNVSN 4900
Query: 893 ETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP--PPPPPRTFQMVTTPF 950
+L AP P + PP SP PPT LV P P PP P + ++P
Sbjct: 4901 LDVRQLSAPPPEE---PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE 4957
Query: 951 PALPQPKA 958
A P+P+A
Sbjct: 4958 SARPKPRA 4965
Score = 45.8 bits (107), Expect = 3e-04
Identities = 45/154 (29%), Positives = 59/154 (38%), Gaps = 9/154 (5%)
Query: 755 SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814
SPA A P +GPG L ++P L P S+ +S
Sbjct: 4822 SPARAGTEPKKGEAEGPG-GKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLK 4880
Query: 815 SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP---PASNPAPTAPGPPQPPLRPQSQPPEG 871
E P P PP Q T + QL PP P+ P+P AP P PP P + P
Sbjct: 4881 QESPA-PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Query: 872 PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
PL PP + +ASS E++ P P +
Sbjct: 4940 PLAE----PPVPSPLPLASSPESARPKPRARPPE 4969
Score = 43.5 bits (101), Expect = 0.002
Identities = 45/146 (30%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 738 PVAKGAGLGPQAPDSQASPAPAPQIPAAAP-------------LKGPGPSSSPSLPHQAP 784
P K GL ++PD+ P Q A P LK P+ P H
Sbjct: 4838 PGGKEKGLEGKSPDT--GPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYT 4895
Query: 785 LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP 844
S R S PP P+ S PPS PL P P +PPT P + + L P
Sbjct: 4896 YN-----VSNLDVRQLSAPP--PEEPSPPPS--PL--APSPASPPTEPLVELPTEPLAEP 4944
Query: 845 PPASNPAPTAPGPPQPPLRPQSQPPE 870
P S P P A P +P+++PPE
Sbjct: 4945 PVPS-PLPLASSPESARPKPRARPPE 4969
Score = 40.8 bits (94), Expect = 0.010
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 19/91 (20%)
Query: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQA 783
+SAPPP + P +P+A P +P ++ P ++P P + P +P
Sbjct: 4906 LSAPPPEEPSPPPSPLAP----SPASPPTE----PLVELPTE-------PLAEPPVPSPL 4950
Query: 784 PLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814
PL SP P +P +RPP + SRPP
Sbjct: 4951 PLASSPESARP---KPRARPPEEGED-SRPP 4977
Score = 40.0 bits (92), Expect = 0.018
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 27/168 (16%)
Query: 657 APPQATTPQPSPGLASSP---EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713
+P +A T +P G A P EK + G+ P P D L+ F A
Sbjct: 4822 SPARAGT-EPKKGEAEGPGGKEKGLEGKSPDTGP------DWLKQF----------DAVL 4864
Query: 714 PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK-GPG 772
P ++ + + + + + PAP P D + AP P+ P+ P P
Sbjct: 4865 PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS 4924
Query: 773 PSSSPSLP----HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSE 816
P+S P+ P PL + P +PSP P S +RP+ +RPP E
Sbjct: 4925 PASPPTEPLVELPTEPLAEPP-VPSPLPL-ASSPESARPKPRARPPEE 4970
Score = 39.3 bits (90), Expect = 0.030
Identities = 172/814 (21%), Positives = 264/814 (32%), Gaps = 142/814 (17%)
Query: 104 LQQSLQEANITEQTLEAEAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGS 163
L++ L I TL E E T A G GP G+ GA + + L G
Sbjct: 2686 LRELLIRQQIQRNTLRQEKE---------TAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQ 2736
Query: 164 TDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPG 223
T G Q +++ +PP + L F L P
Sbjct: 2737 TPFAGTQDKSSLVG----LPPSKLSGPILGPGSFPSDDRLSR---------------PPP 2777
Query: 224 GATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQ 283
AT +++ + Q+VG SQ ++ P G L + Q
Sbjct: 2778 PATPSSMDVNSRQLVGG---------SQAFYQRAPYPGSLP---------------LQQQ 2813
Query: 284 GAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVI 343
L Q+ +AA + ++ F P P LG L I
Sbjct: 2814 QQQLWQQQQATAATSMRFAMSARF----------------PSTPGPELGRQALGSPLAGI 2857
Query: 344 LHRTPTPIQPKPAGVLPPKLYQL---TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFM 400
R P P +P P P + +L K P G QG P P +
Sbjct: 2858 STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLA 2917
Query: 401 AAGKAGQNVVLSGFPA------PALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQ 454
G G + +SG P PA + N P T G P +++P S L +
Sbjct: 2918 PEGLRG--LAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGR 2975
Query: 455 GSSIVIPAQHMLPGQNQFL---LPGAPAVQLPQQLSALPANVGG----------QILAAA 501
+ + + A LP ++ L A++ ++L+ L V + L
Sbjct: 2976 PNPLALEAGK-LPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETN 3034
Query: 502 APHTGGQLIANPILTNQNLAGPLSLGP---VLAPHSGAHSAHILSAAPIQVGQPALFQMP 558
PH L + L G + H ++ +A + + AL +
Sbjct: 3035 DPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEH-----LRLVESANEKAEREALLR-- 3087
Query: 559 VSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPV 618
+ G L + +P PA A+ L V P + P AT +
Sbjct: 3088 -GVEPGPLGPEERPPPAADASEPRLASVL--PEVKPKVEEGGRHPSPCQFTIATPK---- 3140
Query: 619 LTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA---TTPQPSPGLASSPE 675
V+PAP A L LGL+ Q+ + T P + T + S G P
Sbjct: 3141 --VEPAPAA-----NSLGLGLKPGQSMMGSR-DTRMGTGPFSSSGHTAEKASFGATGGPP 3192
Query: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPA--QD- 732
+L P + P + ++ +A G L S +V++ P +D
Sbjct: 3193 AHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDL 3252
Query: 733 -PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
+ K L Q +Q Q + L PGP+ + SLPH+ G SP L
Sbjct: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQ---HSLLSAPGPAQAMSLPHE---GSSPSL 3306
Query: 792 PSPHPT----RPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847
+R P PQ + P++PP H A P + ++ NQ G
Sbjct: 3307 AGSQQQLSLGLAGARQPGLPQPLM--PTQPPAHALQQRLA----PSMAMVSNQ-GHMLSG 3359
Query: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPP 881
+ P Q SQ P G +PP+ + P
Sbjct: 3360 QHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKP 3393
Score = 38.9 bits (89), Expect = 0.039
Identities = 77/334 (23%), Positives = 110/334 (32%), Gaps = 66/334 (19%)
Query: 1232 PGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPS 1291
PGA PPP + I GSP+ + + S++A G +P
Sbjct: 2110 PGALGSPPPAAAPTIFI------GSPT-----------TPAGLSTSADGFLKPPAGSVPG 2152
Query: 1292 RNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPP 1351
+ P + LKL + A + + DP P P + PP PP
Sbjct: 2153 PDSP--------GELFLKLPPQVPAQVP------SQDPFGLAPAYPLEPRFPTAPPTYPP 2198
Query: 1352 PPPPTG-----QMNGTVDHPPPAAP---ERKPLGTAPHCPRL--PLRKTYRENVGGPGAP 1401
P PTG M G P P P GT H P P K ++ P
Sbjct: 2199 YPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVP 2258
Query: 1402 EGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGD 1461
E G + P P E+ + L ++EL PP + +G
Sbjct: 2259 ESPGVGGGKASEPLLSPPPFGESR----KALEVKKEELGASSPSYGPPNLGFVDSPSSGT 2314
Query: 1462 PDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAP 1521
GL + ++PDV +A + + Q + QS + + P + AP
Sbjct: 2315 ---HLGGL------ELKTPDVFKAPLTPRASQVEP-----QSPGLGLRPQEPPPAQALAP 2360
Query: 1522 SYPHAASAGTP-------ASPPPLHRPEAYPPSS 1548
S P P A PP RP+ PP S
Sbjct: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES 2394
Score = 38.1 bits (87), Expect = 0.067
Identities = 61/248 (24%), Positives = 75/248 (30%), Gaps = 50/248 (20%)
Query: 1328 DPVHQPPPPPATLKVAEPP--PRP-------PPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378
DP + P P + ++ P PRP P P P Q PP R P
Sbjct: 2406 DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA- 2464
Query: 1379 APHCPRLPLRKTYRENVGGPGAPEGTPAGRA--RGGSPAPLPAKVDEATSGLIRELAAVE 1436
PL K R G+ A + GG PA LPA
Sbjct: 2465 -------PLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPA--------------GPA 2503
Query: 1437 DELYQRMLKGPPPEPAASAAQGT--GDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQD 1494
EL+ ++ G PP S G G P P A S P V Q P
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL----PPP 2559
Query: 1495 DTLTEHLQSAIDSILNLQQAPGRTPA---------PSYPHAASAGTPASPPPLHRPEAYP 1545
+ H L Q+ T A P P + S G PL P P
Sbjct: 2560 HGINSHFGPG--PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP 2617
Query: 1546 PSSHNGGL 1553
P + +G L
Sbjct: 2618 PPAPDGSL 2625
Score = 37.7 bits (86), Expect = 0.087
Identities = 216/992 (21%), Positives = 330/992 (33%), Gaps = 149/992 (15%)
Query: 133 TLQPA---DGGAGP-TGAGGAAAVAAGPQALF--PGSTDLLGLQGPPTVLTHQALVPPQD 186
T+ PA + GP T GG A+ P+++ PG L G +L Q PQ
Sbjct: 4028 TVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKP-SLSGDSQLLLVQPQPQPQP 4086
Query: 187 VVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALN 246
+L +QP L+ G + + G +G G +++ P ++ QP ++L
Sbjct: 4087 ---SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVP-HLLAQPSVSLG 4142
Query: 247 ----TPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLN 302
+ T LL Q P+ E + G P G V+Q
Sbjct: 4143 DQPGSMTQNLLGPQQPML----------ERPMQNNTGPQPPKPGPVLQSGQ--------- 4183
Query: 303 GNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPK 362
G G PT GQ A G+ L P + H +P Q A ++ +
Sbjct: 4184 -----GLPGVGIMPT---VGQLRAQLQGV----LAKNPQ-LRHLSPQQQQQLQALLMQRQ 4230
Query: 363 LYQL-----TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAP 417
L Q TP P T +QG G PQ P T G L P P
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQT-------GPLQELGAGPRP 4283
Query: 418 ALQANVFKQPPATTTGAA-----PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF 472
+ P A +TG P PP + +P L SS +P + LP +
Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS-QLPTEAQLPPTH-- 4340
Query: 473 LLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAG---PLSLGPV 529
PG P Q P L P V AA T P NLA P V
Sbjct: 4341 --PGTPKPQGPT-LEPPPGRVSPA--AAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395
Query: 530 LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP 589
+ + A+ + + Q + P +L A S+ ++ P G T+ + P
Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQEPR-EEPCALGAQSVKREANGEPIGAPGTSNHLLLAGP 4454
Query: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649
S L L++ +TG + L + ++ GL+Q + Q P
Sbjct: 4455 RSEAGHLLLQK-LLRAKNVQLSTGRGSEGLRAEINGHIDSKLA-----GLEQ-KLQGTPS 4507
Query: 650 APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL 709
AA P TP+P + + +++V + + ++L L QE S PL
Sbjct: 4508 NKEDAAARKP--LTPKPKR-VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPL 4564
Query: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
+ ++ A+ + AP + P +GA S A P
Sbjct: 4565 TEP----AITANFSLFAPFGSGCPVNGQSQLRGAF------GSGALPT------------ 4602
Query: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPP 829
GP L + L + P PS P PP + + P E HP A
Sbjct: 4603 --GPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARD 4660
Query: 830 TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVA 889
+ + + A+ P P P +R +S E P +P SS S +
Sbjct: 4661 SERALRDTSEVKSLDLLAALPTP--PHNQTEDVRMESD--EDSDSPDSIVPASSPESIL- 4715
Query: 890 SSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTP 949
E + R P + + P + L+P + P P + + +
Sbjct: 4716 --GEEAPRFP---------HLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLE 4764
Query: 950 FPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS---PAASVLVSGQAP 1006
P P E+ ++L A A ++ L S P + ++ ++P
Sbjct: 4765 VPG-KLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESP 4823
Query: 1007 SGTPTAPSHAPAPAPMA-ATGL----PPLLPAENKAFASNLP---------TLNVAKAAS 1052
+ T P A P GL P P K F + LP L++ K S
Sbjct: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQES 4883
Query: 1053 SGPGKPSGLQYESKLSG-----LKKPPTLQPS 1079
P P+ Y +S L PP +PS
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS 4915
Score = 37.0 bits (84), Expect = 0.15
Identities = 36/129 (27%), Positives = 48/129 (37%), Gaps = 21/129 (16%)
Query: 921 TPPPTLHL--VPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGG 978
T P LHL P+P A PPP + P P + + L+ AG
Sbjct: 2097 TDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLS-------TSADGFLKPPAGS 2149
Query: 979 APAAPQTSTSLGPLTSPAASVLVSGQAPSGT----------PTA-PSHAPAPAPMAATGL 1027
P P + L P V Q P G PTA P++ P P+P A
Sbjct: 2150 VP-GPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQ 2208
Query: 1028 PPLLPAENK 1036
PP+L A ++
Sbjct: 2209 PPMLGASSR 2217
Score = 37.0 bits (84), Expect = 0.15
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 13/98 (13%)
Query: 565 SLPTQSQPAPAGPAATTVLQGVT--------LPPSAVAMLNTPDGLVQPATPAAATGEAA 616
SL Q PAP P + V+ PP P P P+ A+
Sbjct: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPP-----EEPSPPPSPLAPSPASPPTE 4931
Query: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQ 654
P++ + P A P V +PLPL A+ P+A P+
Sbjct: 4932 PLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969
Score = 36.6 bits (83), Expect = 0.19
Identities = 34/138 (24%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 1327 LDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP--- 1383
L PVH PPP + + P RP P P+ Q+ PP KP G P
Sbjct: 4302 LGPVHPTPPPSSP----QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357
Query: 1384 ----RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
L T GP P A + + +P +D+ ++ E + +
Sbjct: 4358 VSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLS--- 4414
Query: 1440 YQRMLKGPPPEPAASAAQ 1457
+ + P EP A AQ
Sbjct: 4415 ---IKQEPREEPCALGAQ 4429
Score = 31.2 bits (69), Expect = 8.2
Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 1322 VHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPH 1381
V + P +P PPP+ L P P PP P + PP P PL ++P
Sbjct: 4903 VRQLSAPPPEEPSPPPSPL---APSPASPPTEPLVELPTEPLAEPP--VPSPLPLASSPE 4957
Query: 1382 CPR 1384
R
Sbjct: 4958 SAR 4960
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 116 bits (291), Expect = 1e-25
Identities = 213/869 (24%), Positives = 295/869 (33%), Gaps = 138/869 (15%)
Query: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVP--APNVILHRTPTPIQPKPAGVLPPKLYQLTP 368
G P +P+ G G PL P I + P I+ +P G T
Sbjct: 205 GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG---------TG 255
Query: 369 KPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPA---LQANVFK 425
KP G T T Q + LP Q A + T A G++V S P+P+ +Q
Sbjct: 256 KPIQ--GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS-LPSPSKPPIQQPTPG 312
Query: 426 QPPATTTG--------AAPPQPPGALSKPMSVHL------LNQGSSIVIPAQHMLPGQNQ 471
+PPA G A PP P L+KP++ + + PAQ + P +
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Query: 472 FLLPGA--PAVQLP-QQLSALPANVG---GQILAAAAPHTGGQLIANPILTNQNLAGPLS 525
G+ P+ + P + A P VG Q A P T P+ L P
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 526 LG-----PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAAT 580
PV P G A Q + P L + P QP PA P
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
Query: 581 TVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL-GL 639
G PPS QP + + P +P+PQ P + P G
Sbjct: 493 Q--PGSAKPPSQ-----------QPGSTKPPPQQPGPA---KPSPQQPGSTKPPSQQPGS 536
Query: 640 QQPQAQQP-PQAPTPQAAAPPQATT--------PQPSPGLASSPEKIVLGQPPSATPTAI 690
+P AQQP P P+ Q + P + T P SP P + G P + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ---GLPKTICPLCN 593
Query: 691 LTQDSLQMFLPQERSQQPLSA------------EGPHLSV-----------------PAS 721
T+ L + +P++ + + PHL+ +
Sbjct: 594 TTE--LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
Query: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
+ S+P P AP T + + PQ + AP+ + K P P P L
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS---KAPEPKKPPPLVK 708
Query: 782 QAPLGDSPHLPSPHPTRPPS----RPPSRPQSVSRPPSEPPL--HPCPPPQAPPTLPGIF 835
Q L SP + P S PP P S P P P PT +
Sbjct: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Query: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS 895
P+S A PPL+ S P PP S A+ + S
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828
Query: 896 SRLPAPTPSD---FQLQFPPSQ---GPHKSPT---PPPTLHLVPEPAAPPPPPPRTFQMV 946
+ P PS Q Q P Q P K+ T P P +P+ +P PP PR
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQ 887
Query: 947 TTPFP-ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS-----LGPLTSPAASVL 1000
T P P P+P+ RF I K+ P PQ + + G AS L
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKS--QPTTPQETVTGKLFGFGASIFSQASNL 945
Query: 1001 VS-----GQAPSGTPTAP-SHAPAPA-PMAATGLPPLLPAENKAFASNLPTLNVAKAASS 1053
+S G P AP APAP+ P + G P A A ++P KA ++
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005
Query: 1054 GPGKPSGLQYES--KLSGLKKPPTLQPSK 1080
+P Q + + KKPP ++ SK
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPPPIKDSK 1034
Score = 103 bits (256), Expect = 2e-21
Identities = 190/836 (22%), Positives = 264/836 (31%), Gaps = 158/836 (18%)
Query: 261 GYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGT- 319
G+ S GP++P S P K TT G A + TG+
Sbjct: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSE 379
Query: 320 ------PSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAP 373
P + LA PG+G +P + P P +P V PK P +P
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPA---------QQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 374 AGA-----TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPP 428
A A T Q PG +P Q P + A + G S P PA +PP
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTS---AQQTGPTKPPSQLPGPA-------KPP 480
Query: 429 ATTTGAA--PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA-------PA 479
G A PPQ PG+ P Q S P Q P + PG+ P
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQ-----QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 480 VQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSA 539
P PA Q TG P + + P S G ++
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
Query: 540 HILSAAPIQVG-------------------QPALF----------QMPVSLAAGSLPTQS 570
+L P + P L QM +L P S
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQA--- 627
P P + T P + + ++ Q +P +AAP + AP+
Sbjct: 656 SPQP---------KLKTAPVTTTSAVSKSSPQPQQTSPKK---DAAPKQDLSKAPEPKKP 703
Query: 628 PPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG-----QP 682
PP V P G +A+QPP+A + APP+ P + S +K + QP
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK------EPSVPSEQDKAPVADDKPKQP 757
Query: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
PT L S P S + + ++ + P SA P P V+
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
DS+A P PA S S + H P +S P +
Sbjct: 817 --------DSKAIPRPA--------------SDSKIISHPGPSSESKGQKQVDPVQKKEE 854
Query: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862
P +S P P+ P+ PT PG P T P P Q P
Sbjct: 855 PKKAQTKMSPKPDAKPM-----PKGSPTPPG------------PRPTAGQTVPTPQQSP- 896
Query: 863 RPQSQPPE-----GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH 917
+PQ Q G + AP P++ V S+ + GPH
Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL-ISTAGQPGPH 955
Query: 918 KSPTPPPTLHLVPEPAAPPP---PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
P + P P+ PP PP T Q P ++P K + P+ L+
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET-----KAPAAEKLEP 1010
Query: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAP---APMAATGL 1027
KA AP +T T P + L + + PT +P P P+ T L
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
Score = 99.4 bits (246), Expect = 2e-20
Identities = 208/922 (22%), Positives = 307/922 (33%), Gaps = 132/922 (14%)
Query: 636 PLGLQQPQAQQPPQAPTPQAAAPPQATTPQ---PSPGLASSPEKIVLGQP--------PS 684
P G+ +P QQ P P P+ P + Q P + PEKI P P+
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262
Query: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
TP + LQ + +++Q G SV S+ + PP Q P P P A+ G
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGE--SVKPSLPSPSKPPIQQPTPGKPPAQQPG 320
Query: 745 L-----GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
GP P +Q S P +K P + P PLG + +
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 800 PSRPPSRPQSVSRPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP-ASNPAPTAPG 856
PS P+++++PP + P P P PPT Q+G P P A P +P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPT--------QQVGTPKPLAQQPGLQSPA 431
Query: 857 P-PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ- 914
P P P QP G +P A P TS+ ++ S+LP P PP Q
Sbjct: 432 KAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQP 484
Query: 915 GPHKSPTPPPTLHLVP--EPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIIL 972
GP K P P P +P + PPP + P PA P P+ + PS
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQ-------PGPAKPSPQQ--PGSTKPPS---- 531
Query: 973 QNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGLPPLL 1031
Q P+A Q S + S S Q SG P P+ +P+ + GLP +
Sbjct: 532 QQPGSAKPSAQQPSPA---KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Query: 1032 PAENKAFASNLPTLNVAKAASSGPGKPSGLQYES------KLSGLKKPPTLQPSKE-ACF 1084
P N + P K + L G P L KE C
Sbjct: 589 ----------CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
Query: 1085 LEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQL 1144
+ + G L P + P + A P S + + + Q
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTA-----PVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 1145 LKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSS 1204
L + K L+ + + SPSA+ AK+ P+
Sbjct: 694 LSKAPEP-KKPPPLVKQPTLHGSPSAK----------------------AKQPPE----- 725
Query: 1205 SRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARA 1264
+ SL P A + +P + A QP PT ++ A P + ++
Sbjct: 726 ADSLSKP--APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 1265 SSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAG-LSKVVH 1323
S ++ S + P P + +A R KI G S+
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS-KAIPRPASDSKIISHPGPSSESKG 842
Query: 1324 NTALDPVH-QPPPPPATLKVAEPP---------PRPPPPPPPTGQMNGTVDH-PPPAAPE 1372
+DPV + P A K++ P P PP P P GQ T P P
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Query: 1373 RK------PLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATS 1426
R+ + AP ++T + G GA + A + P P +
Sbjct: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
Query: 1427 GLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQAS 1486
+ + A + Q K P A A + +AP + + ++P V +
Sbjct: 963 PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 1487 FSSDSP---QDDTLTEHLQSAI 1505
P +LT Q A+
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAV 1044
Score = 93.2 bits (230), Expect = 2e-18
Identities = 170/677 (25%), Positives = 224/677 (33%), Gaps = 139/677 (20%)
Query: 438 QPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQI 497
+P G + P L Q IP Q PG++ G P QQ P + Q
Sbjct: 202 KPEGIIKPP-----LQQQPPKPIPKQQG-PGRDPLQQDGTPKSISSQQ----PEKIKSQ- 250
Query: 498 LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
P G+ I P T Q L L A A I+ ++ P+ +
Sbjct: 251 -----PPGTGKPIQGPTQTPQTDHAKLPLQRD-ASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 558 PVSLAA-GSLPTQ------SQPAPAGPAATTVLQGVTLP----PSAVAMLNTPDGLVQPA 606
P+ G P Q SQP PA P A G+T P P V P G +P
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP--SGLTKPLAQQPGTVKPPVQPPGTTKPP 362
Query: 607 T--------PAAATGEAAPVLTVQPAPQA---PPAVS-TPLP-----------LGLQQPQ 643
PA TG P + QP P+A PP V TP +G +P
Sbjct: 363 AQPLGPAKPPAQQTGSEKPS-SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421
Query: 644 AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703
AQQP +A P + QP PG + Q P +
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPA-----------------------QQAGPGK 458
Query: 704 RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIP 763
S Q P +P A PP Q P PA P + G S P PQ P
Sbjct: 459 TSAQQTGPTKPPSQLPG----PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
Query: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS------RPPSEP 817
A P S P Q P P P P +P ++ ++P S + +PP+
Sbjct: 515 GPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 818 PLHPCPPPQAPP--TLPGIFVIQNQLGVPPPASNPAPTA------------PGPPQPPLR 863
P PP Q P P + L VP A+ T P P ++
Sbjct: 574 PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633
Query: 864 -------PQSQPPEGPLPPAPHLP-PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQG 915
+ G L P P P P ++ V ++S S P P + + P Q
Sbjct: 634 EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 916 PHKSPTP--------PPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVP 967
K+P P PTLH P A PP + PA P+ + VP
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK-----PAPPKEPS-------VP 741
Query: 968 SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGL 1027
S Q+KA A P+ + P T LVS + + P PS + +
Sbjct: 742 SE---QDKAPVADDKPKQPKMVKPTTD-----LVSSSSATTKPDIPS-SKVQSQAEEKTT 792
Query: 1028 PPLLPAENKAFASNLPT 1044
PPL K S PT
Sbjct: 793 PPLKTDSAKPSQSFPPT 809
Score = 56.2 bits (134), Expect = 2e-07
Identities = 86/368 (23%), Positives = 128/368 (34%), Gaps = 53/368 (14%)
Query: 1222 PGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGG-------SPSVTWARASSSLSSSSSS 1274
PG PL G P K+ + G G +P A+ +S
Sbjct: 225 PGRDPLQQD--GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 1275 SSAASSLDADEDGP-MPSRNRPPIKTY-----------EARSRIGLKLKIKQEAGLSKVV 1322
+ A + + P +PS ++PPI+ +S+ G Q +GL+K +
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 1323 HNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHC 1382
V P PP T K PP +P P P Q G+ + P P K L P
Sbjct: 343 AQQP-GTVKPPVQPPGTTK---PPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQPPGV 397
Query: 1383 PRLPLR-----KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI--RELAAV 1435
+ P + K + VG P P ++ +P P V + G I ++
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 1436 EDELYQRMLKGPP---PEPAASAAQ--GTGDPDWEAPGL--PPAKRRKSESPDVDQASFS 1488
+ Q PP P PA Q G P + PG PP+++ S P Q +
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517
Query: 1489 SDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA---------ASAGTPASPPPLH 1539
SPQ T+ S + + P+P+ P A +G P PP +
Sbjct: 518 KPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 1540 RPEAYPPS 1547
PPS
Sbjct: 574 PSAKQPPS 581
Score = 54.3 bits (129), Expect = 9e-07
Identities = 74/320 (23%), Positives = 115/320 (35%), Gaps = 51/320 (15%)
Query: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667
PA+ +P ++ PA P S+ L + Q P PP P P PP P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP- 2430
Query: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP 727
+SP+ +L + + + T L + + L + G +P + I +
Sbjct: 2431 ----TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG----LPVTRICTTA 2482
Query: 728 PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG- 786
PP P P++ + G + S+ AP P IP P + P+ H P G
Sbjct: 2483 PPPVPPKPSS-IPSGLVFTHRPEPSKPPIAPKPVIPQL-----PTTTQKPTDIHPKPTGL 2536
Query: 787 -----------DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
S P PT P S P S S P+ +L +
Sbjct: 2537 SLTSSMTLNLVTSADYKLPSPTSPLS-PHSNKSS---------------PRFSKSLTETY 2580
Query: 836 VI---QNQLGVPPPASNPAPTAPGPPQPPLRP--QSQPPEGPLPP--APHLPPSSTSS-A 887
V+ ++ G P +S P P + +P +PP A +P SS +
Sbjct: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 888 VASSSETSSRLPAPTPSDFQ 907
++ + +T S P PS FQ
Sbjct: 2641 ISGALQTFSATPVTAPSSFQ 2660
Score = 50.4 bits (119), Expect = 1e-05
Identities = 93/396 (23%), Positives = 134/396 (33%), Gaps = 69/396 (17%)
Query: 1179 FIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQP 1238
F+ E A+ + K P + +S S + + + P P QP
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP 215
Query: 1239 PPHLPTKLVIRHGGAGGSPSVTWARASSSLSSS------SSSSSAASSLDADEDGPMPSR 1292
P +P + G G P + S+SS S + P
Sbjct: 216 PKPIP-----KQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 1293 NRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPP--PPATL---KVAEPPP 1347
+ P++ +R + ++ E+ + + + + P+ QP P PPA + ++P P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGES-VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
Query: 1348 RPPPPPP-----PTGQMNGTVDHP--PPAA--PERKPLGTA-PHCPRLPLRKTYRENVGG 1397
PP P P Q GTV P PP P +PLG A P + K E G
Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388
Query: 1398 PGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPP--PEPAASA 1455
+ P G + + P PAK G + LA Q L+ P P P +
Sbjct: 389 KALAQ--PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ------QPGLQSPAKAPGPTKTP 440
Query: 1456 AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
Q G PG PA+ QA S Q T+ P
Sbjct: 441 VQQPG------PGKIPAQ----------QAGPGKTSAQQTGPTK--------------PP 470
Query: 1516 GRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
+ P P+ P G PA PPP A PPS G
Sbjct: 471 SQLPGPAKPPPQQPG-PAKPPPQQPGSAKPPSQQPG 505
Score = 50.4 bits (119), Expect = 1e-05
Identities = 71/281 (25%), Positives = 96/281 (34%), Gaps = 40/281 (14%)
Query: 812 RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGV---PPPASNPAPTAPGPPQPPLRPQSQP 868
+P S+ P P + P P F + L + PPP P P P PP PP P P
Sbjct: 2371 KPASQLP-SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
Query: 869 PEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
P P P LP + VAS T++ L D + + P +
Sbjct: 2430 PTSPKPTI--LPKKKLT--VASPVTTATPL-----FDAVTTLETTAVLRSNGLPVTRICT 2480
Query: 929 VPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS 988
P PP P +V T P +P P +I Q P Q T
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPI-------APKPVIPQ-----LPTTTQKPTD 2528
Query: 989 LGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKA---FASNLPTL 1045
+ P P L S + +A P+P PL P NK+ F+ +L
Sbjct: 2529 IHP--KPTGLSLTSSMTLNLVTSADYKLPSPT-------SPLSPHSNKSSPRFSKSLTET 2579
Query: 1046 NVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLE 1086
V S PG P+ S + P PSK+ +E
Sbjct: 2580 YVVITLPSEPGTPTD---SSASQAITSWPLGSPSKDLVSVE 2617
Score = 49.7 bits (117), Expect = 2e-05
Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 5/107 (4%)
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP 1383
+++LD QPPPPP PPP PPPPPP + P P++K +P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPP----LPPPTSPKPTILPKKKLTVASPVTT 2451
Query: 1384 RLPLRKTYRE-NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI 1429
PL G P R +P P+P K SGL+
Sbjct: 2452 ATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 116 bits (291), Expect = 1e-25
Identities = 213/869 (24%), Positives = 295/869 (33%), Gaps = 138/869 (15%)
Query: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVP--APNVILHRTPTPIQPKPAGVLPPKLYQLTP 368
G P +P+ G G PL P I + P I+ +P G T
Sbjct: 205 GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG---------TG 255
Query: 369 KPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPA---LQANVFK 425
KP G T T Q + LP Q A + T A G++V S P+P+ +Q
Sbjct: 256 KPIQ--GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS-LPSPSKPPIQQPTPG 312
Query: 426 QPPATTTG--------AAPPQPPGALSKPMSVHL------LNQGSSIVIPAQHMLPGQNQ 471
+PPA G A PP P L+KP++ + + PAQ + P +
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Query: 472 FLLPGA--PAVQLP-QQLSALPANVG---GQILAAAAPHTGGQLIANPILTNQNLAGPLS 525
G+ P+ + P + A P VG Q A P T P+ L P
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 526 LG-----PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAAT 580
PV P G A Q + P L + P QP PA P
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
Query: 581 TVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL-GL 639
G PPS QP + + P +P+PQ P + P G
Sbjct: 493 Q--PGSAKPPSQ-----------QPGSTKPPPQQPGPA---KPSPQQPGSTKPPSQQPGS 536
Query: 640 QQPQAQQP-PQAPTPQAAAPPQATT--------PQPSPGLASSPEKIVLGQPPSATPTAI 690
+P AQQP P P+ Q + P + T P SP P + G P + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ---GLPKTICPLCN 593
Query: 691 LTQDSLQMFLPQERSQQPLSA------------EGPHLSV-----------------PAS 721
T+ L + +P++ + + PHL+ +
Sbjct: 594 TTE--LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
Query: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
+ S+P P AP T + + PQ + AP+ + K P P P L
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS---KAPEPKKPPPLVK 708
Query: 782 QAPLGDSPHLPSPHPTRPPS----RPPSRPQSVSRPPSEPPL--HPCPPPQAPPTLPGIF 835
Q L SP + P S PP P S P P P PT +
Sbjct: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Query: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS 895
P+S A PPL+ S P PP S A+ + S
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828
Query: 896 SRLPAPTPSD---FQLQFPPSQ---GPHKSPT---PPPTLHLVPEPAAPPPPPPRTFQMV 946
+ P PS Q Q P Q P K+ T P P +P+ +P PP PR
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQ 887
Query: 947 TTPFP-ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS-----LGPLTSPAASVL 1000
T P P P+P+ RF I K+ P PQ + + G AS L
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKS--QPTTPQETVTGKLFGFGASIFSQASNL 945
Query: 1001 VS-----GQAPSGTPTAP-SHAPAPA-PMAATGLPPLLPAENKAFASNLPTLNVAKAASS 1053
+S G P AP APAP+ P + G P A A ++P KA ++
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005
Query: 1054 GPGKPSGLQYES--KLSGLKKPPTLQPSK 1080
+P Q + + KKPP ++ SK
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPPPIKDSK 1034
Score = 103 bits (256), Expect = 2e-21
Identities = 190/836 (22%), Positives = 264/836 (31%), Gaps = 158/836 (18%)
Query: 261 GYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGT- 319
G+ S GP++P S P K TT G A + TG+
Sbjct: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSE 379
Query: 320 ------PSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAP 373
P + LA PG+G +P + P P +P V PK P +P
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPA---------QQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 374 AGA-----TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPP 428
A A T Q PG +P Q P + A + G S P PA +PP
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTS---AQQTGPTKPPSQLPGPA-------KPP 480
Query: 429 ATTTGAA--PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA-------PA 479
G A PPQ PG+ P Q S P Q P + PG+ P
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQ-----QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 480 VQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSA 539
P PA Q TG P + + P S G ++
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
Query: 540 HILSAAPIQVG-------------------QPALF----------QMPVSLAAGSLPTQS 570
+L P + P L QM +L P S
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQA--- 627
P P + T P + + ++ Q +P +AAP + AP+
Sbjct: 656 SPQP---------KLKTAPVTTTSAVSKSSPQPQQTSPKK---DAAPKQDLSKAPEPKKP 703
Query: 628 PPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG-----QP 682
PP V P G +A+QPP+A + APP+ P + S +K + QP
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK------EPSVPSEQDKAPVADDKPKQP 757
Query: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
PT L S P S + + ++ + P SA P P V+
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
DS+A P PA S S + H P +S P +
Sbjct: 817 --------DSKAIPRPA--------------SDSKIISHPGPSSESKGQKQVDPVQKKEE 854
Query: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862
P +S P P+ P+ PT PG P T P P Q P
Sbjct: 855 PKKAQTKMSPKPDAKPM-----PKGSPTPPG------------PRPTAGQTVPTPQQSP- 896
Query: 863 RPQSQPPE-----GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH 917
+PQ Q G + AP P++ V S+ + GPH
Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL-ISTAGQPGPH 955
Query: 918 KSPTPPPTLHLVPEPAAPPP---PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
P + P P+ PP PP T Q P ++P K + P+ L+
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET-----KAPAAEKLEP 1010
Query: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAP---APMAATGL 1027
KA AP +T T P + L + + PT +P P P+ T L
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
Score = 99.4 bits (246), Expect = 2e-20
Identities = 208/922 (22%), Positives = 307/922 (33%), Gaps = 132/922 (14%)
Query: 636 PLGLQQPQAQQPPQAPTPQAAAPPQATTPQ---PSPGLASSPEKIVLGQP--------PS 684
P G+ +P QQ P P P+ P + Q P + PEKI P P+
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262
Query: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
TP + LQ + +++Q G SV S+ + PP Q P P P A+ G
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGE--SVKPSLPSPSKPPIQQPTPGKPPAQQPG 320
Query: 745 L-----GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
GP P +Q S P +K P + P PLG + +
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 800 PSRPPSRPQSVSRPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP-ASNPAPTAPG 856
PS P+++++PP + P P P PPT Q+G P P A P +P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPT--------QQVGTPKPLAQQPGLQSPA 431
Query: 857 P-PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ- 914
P P P QP G +P A P TS+ ++ S+LP P PP Q
Sbjct: 432 KAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQP 484
Query: 915 GPHKSPTPPPTLHLVP--EPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIIL 972
GP K P P P +P + PPP + P PA P P+ + PS
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQ-------PGPAKPSPQQ--PGSTKPPS---- 531
Query: 973 QNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGLPPLL 1031
Q P+A Q S + S S Q SG P P+ +P+ + GLP +
Sbjct: 532 QQPGSAKPSAQQPSPA---KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Query: 1032 PAENKAFASNLPTLNVAKAASSGPGKPSGLQYES------KLSGLKKPPTLQPSKE-ACF 1084
P N + P K + L G P L KE C
Sbjct: 589 ----------CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
Query: 1085 LEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQL 1144
+ + G L P + P + A P S + + + Q
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTA-----PVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 1145 LKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSS 1204
L + K L+ + + SPSA+ AK+ P+
Sbjct: 694 LSKAPEP-KKPPPLVKQPTLHGSPSAK----------------------AKQPPE----- 725
Query: 1205 SRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARA 1264
+ SL P A + +P + A QP PT ++ A P + ++
Sbjct: 726 ADSLSKP--APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 1265 SSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAG-LSKVVH 1323
S ++ S + P P + +A R KI G S+
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS-KAIPRPASDSKIISHPGPSSESKG 842
Query: 1324 NTALDPVH-QPPPPPATLKVAEPP---------PRPPPPPPPTGQMNGTVDH-PPPAAPE 1372
+DPV + P A K++ P P PP P P GQ T P P
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Query: 1373 RK------PLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATS 1426
R+ + AP ++T + G GA + A + P P +
Sbjct: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
Query: 1427 GLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQAS 1486
+ + A + Q K P A A + +AP + + ++P V +
Sbjct: 963 PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 1487 FSSDSP---QDDTLTEHLQSAI 1505
P +LT Q A+
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAV 1044
Score = 93.2 bits (230), Expect = 2e-18
Identities = 170/677 (25%), Positives = 224/677 (33%), Gaps = 139/677 (20%)
Query: 438 QPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQI 497
+P G + P L Q IP Q PG++ G P QQ P + Q
Sbjct: 202 KPEGIIKPP-----LQQQPPKPIPKQQG-PGRDPLQQDGTPKSISSQQ----PEKIKSQ- 250
Query: 498 LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
P G+ I P T Q L L A A I+ ++ P+ +
Sbjct: 251 -----PPGTGKPIQGPTQTPQTDHAKLPLQRD-ASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 558 PVSLAA-GSLPTQ------SQPAPAGPAATTVLQGVTLP----PSAVAMLNTPDGLVQPA 606
P+ G P Q SQP PA P A G+T P P V P G +P
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP--SGLTKPLAQQPGTVKPPVQPPGTTKPP 362
Query: 607 T--------PAAATGEAAPVLTVQPAPQA---PPAVS-TPLP-----------LGLQQPQ 643
PA TG P + QP P+A PP V TP +G +P
Sbjct: 363 AQPLGPAKPPAQQTGSEKPS-SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421
Query: 644 AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703
AQQP +A P + QP PG + Q P +
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPA-----------------------QQAGPGK 458
Query: 704 RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIP 763
S Q P +P A PP Q P PA P + G S P PQ P
Sbjct: 459 TSAQQTGPTKPPSQLPG----PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
Query: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS------RPPSEP 817
A P S P Q P P P P +P ++ ++P S + +PP+
Sbjct: 515 GPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 818 PLHPCPPPQAPP--TLPGIFVIQNQLGVPPPASNPAPTA------------PGPPQPPLR 863
P PP Q P P + L VP A+ T P P ++
Sbjct: 574 PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633
Query: 864 -------PQSQPPEGPLPPAPHLP-PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQG 915
+ G L P P P P ++ V ++S S P P + + P Q
Sbjct: 634 EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 916 PHKSPTP--------PPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVP 967
K+P P PTLH P A PP + PA P+ + VP
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK-----PAPPKEPS-------VP 741
Query: 968 SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGL 1027
S Q+KA A P+ + P T LVS + + P PS + +
Sbjct: 742 SE---QDKAPVADDKPKQPKMVKPTTD-----LVSSSSATTKPDIPS-SKVQSQAEEKTT 792
Query: 1028 PPLLPAENKAFASNLPT 1044
PPL K S PT
Sbjct: 793 PPLKTDSAKPSQSFPPT 809
Score = 56.2 bits (134), Expect = 2e-07
Identities = 86/368 (23%), Positives = 128/368 (34%), Gaps = 53/368 (14%)
Query: 1222 PGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGG-------SPSVTWARASSSLSSSSSS 1274
PG PL G P K+ + G G +P A+ +S
Sbjct: 225 PGRDPLQQD--GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 1275 SSAASSLDADEDGP-MPSRNRPPIKTY-----------EARSRIGLKLKIKQEAGLSKVV 1322
+ A + + P +PS ++PPI+ +S+ G Q +GL+K +
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 1323 HNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHC 1382
V P PP T K PP +P P P Q G+ + P P K L P
Sbjct: 343 AQQP-GTVKPPVQPPGTTK---PPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQPPGV 397
Query: 1383 PRLPLR-----KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI--RELAAV 1435
+ P + K + VG P P ++ +P P V + G I ++
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 1436 EDELYQRMLKGPP---PEPAASAAQ--GTGDPDWEAPGL--PPAKRRKSESPDVDQASFS 1488
+ Q PP P PA Q G P + PG PP+++ S P Q +
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517
Query: 1489 SDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA---------ASAGTPASPPPLH 1539
SPQ T+ S + + P+P+ P A +G P PP +
Sbjct: 518 KPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 1540 RPEAYPPS 1547
PPS
Sbjct: 574 PSAKQPPS 581
Score = 54.3 bits (129), Expect = 9e-07
Identities = 74/320 (23%), Positives = 115/320 (35%), Gaps = 51/320 (15%)
Query: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667
PA+ +P ++ PA P S+ L + Q P PP P P PP P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP- 2430
Query: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP 727
+SP+ +L + + + T L + + L + G +P + I +
Sbjct: 2431 ----TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG----LPVTRICTTA 2482
Query: 728 PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG- 786
PP P P++ + G + S+ AP P IP P + P+ H P G
Sbjct: 2483 PPPVPPKPSS-IPSGLVFTHRPEPSKPPIAPKPVIPQL-----PTTTQKPTDIHPKPTGL 2536
Query: 787 -----------DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
S P PT P S P S S P+ +L +
Sbjct: 2537 SLTSSMTLNLVTSADYKLPSPTSPLS-PHSNKSS---------------PRFSKSLTETY 2580
Query: 836 VI---QNQLGVPPPASNPAPTAPGPPQPPLRP--QSQPPEGPLPP--APHLPPSSTSS-A 887
V+ ++ G P +S P P + +P +PP A +P SS +
Sbjct: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 888 VASSSETSSRLPAPTPSDFQ 907
++ + +T S P PS FQ
Sbjct: 2641 ISGALQTFSATPVTAPSSFQ 2660
Score = 50.4 bits (119), Expect = 1e-05
Identities = 93/396 (23%), Positives = 134/396 (33%), Gaps = 69/396 (17%)
Query: 1179 FIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQP 1238
F+ E A+ + K P + +S S + + + P P QP
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP 215
Query: 1239 PPHLPTKLVIRHGGAGGSPSVTWARASSSLSSS------SSSSSAASSLDADEDGPMPSR 1292
P +P + G G P + S+SS S + P
Sbjct: 216 PKPIP-----KQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 1293 NRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPP--PPATL---KVAEPPP 1347
+ P++ +R + ++ E+ + + + + P+ QP P PPA + ++P P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGES-VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
Query: 1348 RPPPPPP-----PTGQMNGTVDHP--PPAA--PERKPLGTA-PHCPRLPLRKTYRENVGG 1397
PP P P Q GTV P PP P +PLG A P + K E G
Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388
Query: 1398 PGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPP--PEPAASA 1455
+ P G + + P PAK G + LA Q L+ P P P +
Sbjct: 389 KALAQ--PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ------QPGLQSPAKAPGPTKTP 440
Query: 1456 AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
Q G PG PA+ QA S Q T+ P
Sbjct: 441 VQQPG------PGKIPAQ----------QAGPGKTSAQQTGPTK--------------PP 470
Query: 1516 GRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
+ P P+ P G PA PPP A PPS G
Sbjct: 471 SQLPGPAKPPPQQPG-PAKPPPQQPGSAKPPSQQPG 505
Score = 50.4 bits (119), Expect = 1e-05
Identities = 71/281 (25%), Positives = 96/281 (34%), Gaps = 40/281 (14%)
Query: 812 RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGV---PPPASNPAPTAPGPPQPPLRPQSQP 868
+P S+ P P + P P F + L + PPP P P P PP PP P P
Sbjct: 2371 KPASQLP-SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
Query: 869 PEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
P P P LP + VAS T++ L D + + P +
Sbjct: 2430 PTSPKPTI--LPKKKLT--VASPVTTATPL-----FDAVTTLETTAVLRSNGLPVTRICT 2480
Query: 929 VPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS 988
P PP P +V T P +P P +I Q P Q T
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPI-------APKPVIPQ-----LPTTTQKPTD 2528
Query: 989 LGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKA---FASNLPTL 1045
+ P P L S + +A P+P PL P NK+ F+ +L
Sbjct: 2529 IHP--KPTGLSLTSSMTLNLVTSADYKLPSPT-------SPLSPHSNKSSPRFSKSLTET 2579
Query: 1046 NVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLE 1086
V S PG P+ S + P PSK+ +E
Sbjct: 2580 YVVITLPSEPGTPTD---SSASQAITSWPLGSPSKDLVSVE 2617
Score = 49.7 bits (117), Expect = 2e-05
Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 5/107 (4%)
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP 1383
+++LD QPPPPP PPP PPPPPP + P P++K +P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPP----LPPPTSPKPTILPKKKLTVASPVTT 2451
Query: 1384 RLPLRKTYRE-NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI 1429
PL G P R +P P+P K SGL+
Sbjct: 2452 ATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 110 bits (274), Expect = 1e-23
Identities = 138/483 (28%), Positives = 170/483 (35%), Gaps = 105/483 (21%)
Query: 604 QPATPAAATGEAAPVLTVQPAPQAPP----------AVSTPLPLGLQQPQ---AQQPPQA 650
+P +P+ GE++ +V + P + S P P + AQQ
Sbjct: 122 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181
Query: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710
P A P TP PS +P+ G PSA TA+ Q S SQ P
Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA--TAVPPQGS------PTASQAPNQ 233
Query: 711 AEGPHLSVPASVIVSA------------PPPAQDPAPATPVAKGAGLGPQAPDSQASP-- 756
+ P VP + I A PPP P P G+ P AP P
Sbjct: 234 PQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 293
Query: 757 ---APAPQIPAAAP-LKGPGPSSSPSLP-----HQAPLGDSPHLPSPHPT---------- 797
P P A P L+ PGP LP QAPLG SP PH +
Sbjct: 294 GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 353
Query: 798 ---RPPSRPPSRPQSVS----RPPSEPPLHPCPPPQA---PPTLPGIFVIQNQLGVPPP- 846
+PP P P ++ +PP P+ P PQA PP L G +PPP
Sbjct: 354 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 413
Query: 847 -------ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899
S P + PP L PQSQ PLP +P PP T S LP
Sbjct: 414 ALKPLSSLSTHHPPSAHPPPLQLMPQSQ----PLPSSPAQPPGLTQ---------SQNLP 460
Query: 900 APTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL 959
P S P G H+ PP P PPP P T +TP PA P A
Sbjct: 461 PPPASH------PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-PAGPGTSA- 512
Query: 960 LERFHQVP-SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPA 1018
Q P SG A G A +S L P L + P +P P +P+
Sbjct: 513 -----QPPCSGA----AASGGSIAGGSSCPL-PTVQIKEEALDDAEEPE-SPPPPPRSPS 561
Query: 1019 PAP 1021
P P
Sbjct: 562 PEP 564
Score = 110 bits (274), Expect = 1e-23
Identities = 131/416 (31%), Positives = 163/416 (39%), Gaps = 67/416 (16%)
Query: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP 628
Q Q A P A GVT PS+ A TP TP+A T AP P
Sbjct: 176 QQQMLQAQPPALQAPTGVTPAPSS-APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234
Query: 629 PAVSTPLP-LGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVLGQPP--- 683
A + P+P +QQ A P + P+P P P QP G A P QPP
Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 294
Query: 684 --SATPTAILTQDSLQ-------MFLPQERSQ--QPL----SAEGPH--LSVPAS--VIV 724
P ++ LQ LP + SQ PL +A PH L +PAS +
Sbjct: 295 QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 354
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA-PAPQIPAAAPLKGPGPSSSPSLPHQA 783
S PP + P P P+A P + P P PQ+PA K P S PS
Sbjct: 355 SQQPPREQPLPPAPLAM--------PHIKPPPTTPIPQLPAPQAHKHPPHLSGPS----- 401
Query: 784 PLGDSPHLPSPHPTRP-PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P + +LP P +P S P S PP + P P +P PG+ Q+Q
Sbjct: 402 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--TQSQNL 459
Query: 843 VPPPASNPAPT-----APGPP----------QPPLRP-----QSQPPEGPLPPAPHLPPS 882
PPPAS+P PT AP PP PP+ P S PP GP A PP
Sbjct: 460 PPPPASHP-PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ--PPC 516
Query: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
S ++A S S P PT + ++ P +SP PPP PEP P
Sbjct: 517 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP-ESPPPPPR-SPSPEPTVVDTP 570
Score = 106 bits (264), Expect = 2e-22
Identities = 141/540 (26%), Positives = 196/540 (36%), Gaps = 91/540 (16%)
Query: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ-----AQQPPQAPTPQA 655
G P+ + ++ ++ + A + S+PL +Q + ++ + + +
Sbjct: 56 GRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKT 115
Query: 656 AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715
+ PS G S + + S+ P I QD+ + P S Q ++
Sbjct: 116 KTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI-DQDN-RSTSPSIPSPQDNESDSDS 173
Query: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLG-PQAPDSQASPAPAPQIPAAAPLKGPGPS 774
S ++ + PP Q P TP A G PQ P +P P P A P P S
Sbjct: 174 -SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAVPPQGSPTAS 228
Query: 775 SSPSLPHQAPLGDSPHL-----PSPHPTRPPS-RPPSRPQSVSRPPSEPPL----HPCPP 824
+P+ P QAP PH P+ HP RPPS PP P PP +P P P
Sbjct: 229 QAPNQP-QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPSAP 285
Query: 825 PQAPPTLPGIFVIQNQLGVPPPAS---NPAPTAPGPPQP----PLRPQSQPPEGPLPPAP 877
A P L G G P P S P PGPPQP P Q Q P G P A
Sbjct: 286 SHAQPPLHG-------QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 338
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA--- 934
+ P ++ AS S S+ P P + L P PH P P + +P P A
Sbjct: 339 Y--PHTSLQLPASQSALQSQQP---PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH 393
Query: 935 ----------------PPPPPPRTFQMVTTPFP--ALPQPKALLERFHQVPSGI-----I 971
PPPP + ++T P A P P L+ + +PS +
Sbjct: 394 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 453
Query: 972 LQNKAGGAPAAPQTSTSL---GPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGL 1027
Q++ P A T L P A V G P TP T PS + PA +
Sbjct: 454 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 513
Query: 1028 PPL--LPAENKAFASN----LPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
PP A + A LPT+ + + A +P PP PS E
Sbjct: 514 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPES----------PPPPPRSPSPE 563
Score = 80.9 bits (198), Expect = 9e-15
Identities = 123/432 (28%), Positives = 147/432 (34%), Gaps = 79/432 (18%)
Query: 405 AGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQH 464
+ Q +L P PALQA P ++ PQ P P + + QGS P
Sbjct: 174 SAQQQMLQAQP-PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----PTAS 228
Query: 465 MLPGQNQFLLPGAPAVQLP----QQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNL 520
P Q P AP +P QQ AL +PH +P L Q L
Sbjct: 229 QAPNQ-----PQAPTAPVPHTHIQQAPALHPQ------RPPSPHPPPHPSPHPPL--QPL 275
Query: 521 AGPLSLGPVLAPH--------SGAHSAHILSAAPI--QVGQPALFQMPVSLAAGSLPTQS 570
G S G AP G H L A P+ G P F +P + G P +
Sbjct: 276 TG--SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT 333
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA-AATGEAAPVLTVQ----PAP 625
PA A P + + LP S A+ + QP PA A P T PAP
Sbjct: 334 SPAAAYPHTS-----LQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 388
Query: 626 QA---PPAVSTPLPLGLQQPQAQQPPQAP--------TPQAAAPPQATTPQPSPGLASSP 674
QA PP +S P P + P P P A PP PQ P L SSP
Sbjct: 389 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP-LPSSP 447
Query: 675 EKIVLGQPPSAT-------PTAILTQDSLQMFLPQER-SQQPLSAEGPHLSVPASVIVSA 726
QPP T P A L PQ +Q P GP P + ++
Sbjct: 448 -----AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502
Query: 727 PPPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPL 785
PPA A P GA G + P P QI A P S P
Sbjct: 503 TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-------- 554
Query: 786 GDSPHLPSPHPT 797
P PSP PT
Sbjct: 555 -PPPRSPSPEPT 565
Score = 67.8 bits (164), Expect = 8e-11
Identities = 123/440 (27%), Positives = 152/440 (34%), Gaps = 76/440 (17%)
Query: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP 370
G AP+ P G P PG P P+ T P Q P P Q P
Sbjct: 192 GVTPAPSSAPPGTPQLPTPG-------PTPSA----TAVPPQGSPTASQAPNQPQ---AP 237
Query: 371 FAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPAT 430
AP T IQ P PQ+P +P P P + QP
Sbjct: 238 TAPVPHT-HIQQAPALHPQRPPSPH-------------------PPPHPSPHPPLQP--L 275
Query: 431 TTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAP-AVQLPQQLSAL 489
T A P P P L QG P H L PG P LP Q S
Sbjct: 276 TGSAGQPSAPSHAQPP----LHGQGP----PGPHSLQAGPLLQHPGPPQPFGLPPQASQG 327
Query: 490 PANVGGQILAAAAPHTGGQLIAN-PILTNQN--LAGPLSLGPVLAPHSGAHSAHILSAAP 546
A +G AAA PHT QL A+ L +Q PL P+ PH P
Sbjct: 328 QAPLGTS-PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP-----PTTP 381
Query: 547 I-QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT-LPPSAVAMLNTPDGLVQ 604
I Q+ P + P L+ S + + P PA + T PPSA + P +
Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA----HPPPLQLM 437
Query: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664
P + + A P Q PP S P P GL Q A QPP A P P TP
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQ-VAPQPPFAQHPFVPGGPPPITP 495
Query: 665 QPSPGLASSPE-KIVLGQPP----SATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
P ++ P QPP +A+ +I S + Q + + AE P
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE---- 551
Query: 720 ASVIVSAPPPAQDPAPATPV 739
S PPP + P+P V
Sbjct: 552 -----SPPPPPRSPSPEPTV 566
Score = 42.7 bits (99), Expect = 0.003
Identities = 105/459 (22%), Positives = 150/459 (32%), Gaps = 67/459 (14%)
Query: 1126 SPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPS-AEMVMIDRMFIQEEK 1184
SP +K E T+ RT + K + E SR SPS E D + +E
Sbjct: 88 SPLKSNKRQREKVASDTEEADRTSSKKTKTQ----EISRPNSPSEGEGESSDSRSVNDEG 143
Query: 1185 TTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSS----APGASTQPP- 1239
++ D + S + +S++ L P + P S+ PP
Sbjct: 144 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203
Query: 1240 -PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSS-----SAASSLDADEDGPMPSRN 1293
P LPT G +PS T S ++S + + +A + P
Sbjct: 204 TPQLPTP--------GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 255
Query: 1294 RPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVH-QPPPPPATLKVAEPPPRPPPP 1352
RPP L+ + + A P+H Q PP P +L+ A P + P P
Sbjct: 256 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ-AGPLLQHPGP 314
Query: 1353 PPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGG 1412
P P G PP A+ + PLGT+P T + A + R +
Sbjct: 315 PQPFGL-------PPQASQGQAPLGTSPAAA---YPHTSLQLPASQSALQSQQPPREQPL 364
Query: 1413 SPAPLPAK-VDEATSGLIRELAAVEDELYQRMLKGP---------PPEPAASAAQGTGDP 1462
PAPL + + I +L A + + L GP PP PA
Sbjct: 365 PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 424
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP--- 1519
+ PP + P S Q LT+ NL P P
Sbjct: 425 HPPSAHPPPLQLMPQSQP------LPSSPAQPPGLTQSQ--------NLPPPPASHPPTG 470
Query: 1520 ----APSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLG 1554
AP P A P PPP+ P S+ G G
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 509
Score = 41.2 bits (95), Expect = 0.008
Identities = 79/309 (25%), Positives = 97/309 (31%), Gaps = 77/309 (24%)
Query: 1207 SLGLPIAASSEGHRLPGHGPLS----SSAPGASTQPPPH---LPTKLVIRHGGAGGSPSV 1259
S G P A S L G GP + P PP LP + G SP+
Sbjct: 278 SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337
Query: 1260 TWARASSSLSSSSSSSSAASSLDADEDGP-------MPSRNRPPIKTYEARSRIGLKLKI 1312
+ S L +S S A S + P MP PP
Sbjct: 338 AYPHTSLQLPASQS---ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394
Query: 1313 KQEAGLSKVVHNTALDP-----------VHQPP---PPPATL---------KVAEPP--- 1346
+G S N L P H PP PPP L A+PP
Sbjct: 395 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
Query: 1347 -----PRPPPPPPPTGQMNGTVDHPP----PAAPERKPLGTAPHCPRLPLRKTYRENVGG 1397
P PP PPTG ++ PP P P P T P CP + G
Sbjct: 455 QSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP------STSTPPAG 507
Query: 1398 PGAPEGTP-------AGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE 1450
PG P G GGS PLP + I+E A + E + PPP
Sbjct: 508 PGTSAQPPCSGAAASGGSIAGGSSCPLP-------TVQIKEEALDDAE----EPESPPPP 556
Query: 1451 PAASAAQGT 1459
P + + + T
Sbjct: 557 PRSPSPEPT 565
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 110 bits (274), Expect = 1e-23
Identities = 138/483 (28%), Positives = 170/483 (35%), Gaps = 105/483 (21%)
Query: 604 QPATPAAATGEAAPVLTVQPAPQAPP----------AVSTPLPLGLQQPQ---AQQPPQA 650
+P +P+ GE++ +V + P + S P P + AQQ
Sbjct: 676 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735
Query: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710
P A P TP PS +P+ G PSA TA+ Q S SQ P
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA--TAVPPQGS------PTASQAPNQ 787
Query: 711 AEGPHLSVPASVIVSA------------PPPAQDPAPATPVAKGAGLGPQAPDSQASP-- 756
+ P VP + I A PPP P P G+ P AP P
Sbjct: 788 PQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 847
Query: 757 ---APAPQIPAAAP-LKGPGPSSSPSLP-----HQAPLGDSPHLPSPHPT---------- 797
P P A P L+ PGP LP QAPLG SP PH +
Sbjct: 848 GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 907
Query: 798 ---RPPSRPPSRPQSVS----RPPSEPPLHPCPPPQA---PPTLPGIFVIQNQLGVPPP- 846
+PP P P ++ +PP P+ P PQA PP L G +PPP
Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 967
Query: 847 -------ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899
S P + PP L PQSQ PLP +P PP T S LP
Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQSQ----PLPSSPAQPPGLTQ---------SQNLP 1014
Query: 900 APTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL 959
P S P G H+ PP P PPP P T +TP PA P A
Sbjct: 1015 PPPASH------PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-PAGPGTSA- 1066
Query: 960 LERFHQVP-SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPA 1018
Q P SG A G A +S L P L + P +P P +P+
Sbjct: 1067 -----QPPCSGA----AASGGSIAGGSSCPL-PTVQIKEEALDDAEEPE-SPPPPPRSPS 1115
Query: 1019 PAP 1021
P P
Sbjct: 1116 PEP 1118
Score = 110 bits (274), Expect = 1e-23
Identities = 131/416 (31%), Positives = 163/416 (39%), Gaps = 67/416 (16%)
Query: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP 628
Q Q A P A GVT PS+ A TP TP+A T AP P
Sbjct: 730 QQQMLQAQPPALQAPTGVTPAPSS-APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788
Query: 629 PAVSTPLP-LGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVLGQPP--- 683
A + P+P +QQ A P + P+P P P QP G A P QPP
Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 848
Query: 684 --SATPTAILTQDSLQ-------MFLPQERSQ--QPL----SAEGPH--LSVPAS--VIV 724
P ++ LQ LP + SQ PL +A PH L +PAS +
Sbjct: 849 QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 908
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA-PAPQIPAAAPLKGPGPSSSPSLPHQA 783
S PP + P P P+A P + P P PQ+PA K P S PS
Sbjct: 909 SQQPPREQPLPPAPLAM--------PHIKPPPTTPIPQLPAPQAHKHPPHLSGPS----- 955
Query: 784 PLGDSPHLPSPHPTRP-PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P + +LP P +P S P S PP + P P +P PG+ Q+Q
Sbjct: 956 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--TQSQNL 1013
Query: 843 VPPPASNPAPT-----APGPP----------QPPLRP-----QSQPPEGPLPPAPHLPPS 882
PPPAS+P PT AP PP PP+ P S PP GP A PP
Sbjct: 1014 PPPPASHP-PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ--PPC 1070
Query: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
S ++A S S P PT + ++ P +SP PPP PEP P
Sbjct: 1071 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP-ESPPPPPR-SPSPEPTVVDTP 1124
Score = 106 bits (264), Expect = 2e-22
Identities = 141/540 (26%), Positives = 196/540 (36%), Gaps = 91/540 (16%)
Query: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ-----AQQPPQAPTPQA 655
G P+ + ++ ++ + A + S+PL +Q + ++ + + +
Sbjct: 610 GRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKT 669
Query: 656 AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715
+ PS G S + + S+ P I QD+ + P S Q ++
Sbjct: 670 KTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI-DQDN-RSTSPSIPSPQDNESDSDS 727
Query: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLG-PQAPDSQASPAPAPQIPAAAPLKGPGPS 774
S ++ + PP Q P TP A G PQ P +P P P A P P S
Sbjct: 728 -SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAVPPQGSPTAS 782
Query: 775 SSPSLPHQAPLGDSPHL-----PSPHPTRPPS-RPPSRPQSVSRPPSEPPL----HPCPP 824
+P+ P QAP PH P+ HP RPPS PP P PP +P P P
Sbjct: 783 QAPNQP-QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPSAP 839
Query: 825 PQAPPTLPGIFVIQNQLGVPPPAS---NPAPTAPGPPQP----PLRPQSQPPEGPLPPAP 877
A P L G G P P S P PGPPQP P Q Q P G P A
Sbjct: 840 SHAQPPLHG-------QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 892
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA--- 934
+ P ++ AS S S+ P P + L P PH P P + +P P A
Sbjct: 893 Y--PHTSLQLPASQSALQSQQP---PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH 947
Query: 935 ----------------PPPPPPRTFQMVTTPFP--ALPQPKALLERFHQVPSGI-----I 971
PPPP + ++T P A P P L+ + +PS +
Sbjct: 948 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 1007
Query: 972 LQNKAGGAPAAPQTSTSL---GPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGL 1027
Q++ P A T L P A V G P TP T PS + PA +
Sbjct: 1008 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 1067
Query: 1028 PPL--LPAENKAFASN----LPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
PP A + A LPT+ + + A +P PP PS E
Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPES----------PPPPPRSPSPE 1117
Score = 80.9 bits (198), Expect = 9e-15
Identities = 123/432 (28%), Positives = 147/432 (34%), Gaps = 79/432 (18%)
Query: 405 AGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQH 464
+ Q +L P PALQA P ++ PQ P P + + QGS P
Sbjct: 728 SAQQQMLQAQP-PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----PTAS 782
Query: 465 MLPGQNQFLLPGAPAVQLP----QQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNL 520
P Q P AP +P QQ AL +PH +P L Q L
Sbjct: 783 QAPNQ-----PQAPTAPVPHTHIQQAPALHPQ------RPPSPHPPPHPSPHPPL--QPL 829
Query: 521 AGPLSLGPVLAPH--------SGAHSAHILSAAPI--QVGQPALFQMPVSLAAGSLPTQS 570
G S G AP G H L A P+ G P F +P + G P +
Sbjct: 830 TG--SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT 887
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA-AATGEAAPVLTVQ----PAP 625
PA A P + + LP S A+ + QP PA A P T PAP
Sbjct: 888 SPAAAYPHTS-----LQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942
Query: 626 QA---PPAVSTPLPLGLQQPQAQQPPQAP--------TPQAAAPPQATTPQPSPGLASSP 674
QA PP +S P P + P P P A PP PQ P L SSP
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP-LPSSP 1001
Query: 675 EKIVLGQPPSAT-------PTAILTQDSLQMFLPQER-SQQPLSAEGPHLSVPASVIVSA 726
QPP T P A L PQ +Q P GP P + ++
Sbjct: 1002 -----AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056
Query: 727 PPPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPL 785
PPA A P GA G + P P QI A P S P
Sbjct: 1057 TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-------- 1108
Query: 786 GDSPHLPSPHPT 797
P PSP PT
Sbjct: 1109 -PPPRSPSPEPT 1119
Score = 67.8 bits (164), Expect = 8e-11
Identities = 123/440 (27%), Positives = 152/440 (34%), Gaps = 76/440 (17%)
Query: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP 370
G AP+ P G P PG P P+ T P Q P P Q P
Sbjct: 746 GVTPAPSSAPPGTPQLPTPG-------PTPSA----TAVPPQGSPTASQAPNQPQ---AP 791
Query: 371 FAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPAT 430
AP T IQ P PQ+P +P P P + QP
Sbjct: 792 TAPVPHT-HIQQAPALHPQRPPSPH-------------------PPPHPSPHPPLQP--L 829
Query: 431 TTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAP-AVQLPQQLSAL 489
T A P P P L QG P H L PG P LP Q S
Sbjct: 830 TGSAGQPSAPSHAQPP----LHGQGP----PGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 490 PANVGGQILAAAAPHTGGQLIAN-PILTNQN--LAGPLSLGPVLAPHSGAHSAHILSAAP 546
A +G AAA PHT QL A+ L +Q PL P+ PH P
Sbjct: 882 QAPLGTS-PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP-----PTTP 935
Query: 547 I-QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT-LPPSAVAMLNTPDGLVQ 604
I Q+ P + P L+ S + + P PA + T PPSA + P +
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA----HPPPLQLM 991
Query: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664
P + + A P Q PP S P P GL Q A QPP A P P TP
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQ-VAPQPPFAQHPFVPGGPPPITP 1049
Query: 665 QPSPGLASSPE-KIVLGQPP----SATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
P ++ P QPP +A+ +I S + Q + + AE P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE---- 1105
Query: 720 ASVIVSAPPPAQDPAPATPV 739
S PPP + P+P V
Sbjct: 1106 -----SPPPPPRSPSPEPTV 1120
Score = 42.7 bits (99), Expect = 0.003
Identities = 105/459 (22%), Positives = 150/459 (32%), Gaps = 67/459 (14%)
Query: 1126 SPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPS-AEMVMIDRMFIQEEK 1184
SP +K E T+ RT + K + E SR SPS E D + +E
Sbjct: 642 SPLKSNKRQREKVASDTEEADRTSSKKTKTQ----EISRPNSPSEGEGESSDSRSVNDEG 697
Query: 1185 TTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSS----APGASTQPP- 1239
++ D + S + +S++ L P + P S+ PP
Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757
Query: 1240 -PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSS-----SAASSLDADEDGPMPSRN 1293
P LPT G +PS T S ++S + + +A + P
Sbjct: 758 TPQLPTP--------GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809
Query: 1294 RPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVH-QPPPPPATLKVAEPPPRPPPP 1352
RPP L+ + + A P+H Q PP P +L+ A P + P P
Sbjct: 810 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ-AGPLLQHPGP 868
Query: 1353 PPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGG 1412
P P G PP A+ + PLGT+P T + A + R +
Sbjct: 869 PQPFGL-------PPQASQGQAPLGTSPAAA---YPHTSLQLPASQSALQSQQPPREQPL 918
Query: 1413 SPAPLPAK-VDEATSGLIRELAAVEDELYQRMLKGP---------PPEPAASAAQGTGDP 1462
PAPL + + I +L A + + L GP PP PA
Sbjct: 919 PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 978
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP--- 1519
+ PP + P S Q LT+ NL P P
Sbjct: 979 HPPSAHPPPLQLMPQSQP------LPSSPAQPPGLTQSQ--------NLPPPPASHPPTG 1024
Query: 1520 ----APSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLG 1554
AP P A P PPP+ P S+ G G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063
Score = 41.2 bits (95), Expect = 0.008
Identities = 79/309 (25%), Positives = 97/309 (31%), Gaps = 77/309 (24%)
Query: 1207 SLGLPIAASSEGHRLPGHGPLS----SSAPGASTQPPPH---LPTKLVIRHGGAGGSPSV 1259
S G P A S L G GP + P PP LP + G SP+
Sbjct: 832 SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891
Query: 1260 TWARASSSLSSSSSSSSAASSLDADEDGP-------MPSRNRPPIKTYEARSRIGLKLKI 1312
+ S L +S S A S + P MP PP
Sbjct: 892 AYPHTSLQLPASQS---ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948
Query: 1313 KQEAGLSKVVHNTALDP-----------VHQPP---PPPATL---------KVAEPP--- 1346
+G S N L P H PP PPP L A+PP
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 1008
Query: 1347 -----PRPPPPPPPTGQMNGTVDHPP----PAAPERKPLGTAPHCPRLPLRKTYRENVGG 1397
P PP PPTG ++ PP P P P T P CP + G
Sbjct: 1009 QSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP------STSTPPAG 1061
Query: 1398 PGAPEGTP-------AGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE 1450
PG P G GGS PLP + I+E A + E + PPP
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLP-------TVQIKEEALDDAE----EPESPPPP 1110
Query: 1451 PAASAAQGT 1459
P + + + T
Sbjct: 1111 PRSPSPEPT 1119
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 110 bits (274), Expect = 1e-23
Identities = 138/483 (28%), Positives = 170/483 (35%), Gaps = 105/483 (21%)
Query: 604 QPATPAAATGEAAPVLTVQPAPQAPP----------AVSTPLPLGLQQPQ---AQQPPQA 650
+P +P+ GE++ +V + P + S P P + AQQ
Sbjct: 676 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735
Query: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710
P A P TP PS +P+ G PSA TA+ Q S SQ P
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA--TAVPPQGS------PTASQAPNQ 787
Query: 711 AEGPHLSVPASVIVSA------------PPPAQDPAPATPVAKGAGLGPQAPDSQASP-- 756
+ P VP + I A PPP P P G+ P AP P
Sbjct: 788 PQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 847
Query: 757 ---APAPQIPAAAP-LKGPGPSSSPSLP-----HQAPLGDSPHLPSPHPT---------- 797
P P A P L+ PGP LP QAPLG SP PH +
Sbjct: 848 GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 907
Query: 798 ---RPPSRPPSRPQSVS----RPPSEPPLHPCPPPQA---PPTLPGIFVIQNQLGVPPP- 846
+PP P P ++ +PP P+ P PQA PP L G +PPP
Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 967
Query: 847 -------ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899
S P + PP L PQSQ PLP +P PP T S LP
Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQSQ----PLPSSPAQPPGLTQ---------SQNLP 1014
Query: 900 APTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL 959
P S P G H+ PP P PPP P T +TP PA P A
Sbjct: 1015 PPPASH------PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-PAGPGTSA- 1066
Query: 960 LERFHQVP-SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPA 1018
Q P SG A G A +S L P L + P +P P +P+
Sbjct: 1067 -----QPPCSGA----AASGGSIAGGSSCPL-PTVQIKEEALDDAEEPE-SPPPPPRSPS 1115
Query: 1019 PAP 1021
P P
Sbjct: 1116 PEP 1118
Score = 110 bits (274), Expect = 1e-23
Identities = 131/416 (31%), Positives = 163/416 (39%), Gaps = 67/416 (16%)
Query: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP 628
Q Q A P A GVT PS+ A TP TP+A T AP P
Sbjct: 730 QQQMLQAQPPALQAPTGVTPAPSS-APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788
Query: 629 PAVSTPLP-LGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVLGQPP--- 683
A + P+P +QQ A P + P+P P P QP G A P QPP
Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 848
Query: 684 --SATPTAILTQDSLQ-------MFLPQERSQ--QPL----SAEGPH--LSVPAS--VIV 724
P ++ LQ LP + SQ PL +A PH L +PAS +
Sbjct: 849 QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 908
Query: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA-PAPQIPAAAPLKGPGPSSSPSLPHQA 783
S PP + P P P+A P + P P PQ+PA K P S PS
Sbjct: 909 SQQPPREQPLPPAPLAM--------PHIKPPPTTPIPQLPAPQAHKHPPHLSGPS----- 955
Query: 784 PLGDSPHLPSPHPTRP-PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
P + +LP P +P S P S PP + P P +P PG+ Q+Q
Sbjct: 956 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL--TQSQNL 1013
Query: 843 VPPPASNPAPT-----APGPP----------QPPLRP-----QSQPPEGPLPPAPHLPPS 882
PPPAS+P PT AP PP PP+ P S PP GP A PP
Sbjct: 1014 PPPPASHP-PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ--PPC 1070
Query: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
S ++A S S P PT + ++ P +SP PPP PEP P
Sbjct: 1071 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP-ESPPPPPR-SPSPEPTVVDTP 1124
Score = 106 bits (264), Expect = 2e-22
Identities = 141/540 (26%), Positives = 196/540 (36%), Gaps = 91/540 (16%)
Query: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ-----AQQPPQAPTPQA 655
G P+ + ++ ++ + A + S+PL +Q + ++ + + +
Sbjct: 610 GRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKT 669
Query: 656 AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715
+ PS G S + + S+ P I QD+ + P S Q ++
Sbjct: 670 KTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI-DQDN-RSTSPSIPSPQDNESDSDS 727
Query: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLG-PQAPDSQASPAPAPQIPAAAPLKGPGPS 774
S ++ + PP Q P TP A G PQ P +P P P A P P S
Sbjct: 728 -SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAVPPQGSPTAS 782
Query: 775 SSPSLPHQAPLGDSPHL-----PSPHPTRPPS-RPPSRPQSVSRPPSEPPL----HPCPP 824
+P+ P QAP PH P+ HP RPPS PP P PP +P P P
Sbjct: 783 QAPNQP-QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPSAP 839
Query: 825 PQAPPTLPGIFVIQNQLGVPPPAS---NPAPTAPGPPQP----PLRPQSQPPEGPLPPAP 877
A P L G G P P S P PGPPQP P Q Q P G P A
Sbjct: 840 SHAQPPLHG-------QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 892
Query: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA--- 934
+ P ++ AS S S+ P P + L P PH P P + +P P A
Sbjct: 893 Y--PHTSLQLPASQSALQSQQP---PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH 947
Query: 935 ----------------PPPPPPRTFQMVTTPFP--ALPQPKALLERFHQVPSGI-----I 971
PPPP + ++T P A P P L+ + +PS +
Sbjct: 948 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 1007
Query: 972 LQNKAGGAPAAPQTSTSL---GPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGL 1027
Q++ P A T L P A V G P TP T PS + PA +
Sbjct: 1008 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 1067
Query: 1028 PPL--LPAENKAFASN----LPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
PP A + A LPT+ + + A +P PP PS E
Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPES----------PPPPPRSPSPE 1117
Score = 80.9 bits (198), Expect = 9e-15
Identities = 123/432 (28%), Positives = 147/432 (34%), Gaps = 79/432 (18%)
Query: 405 AGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQH 464
+ Q +L P PALQA P ++ PQ P P + + QGS P
Sbjct: 728 SAQQQMLQAQP-PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----PTAS 782
Query: 465 MLPGQNQFLLPGAPAVQLP----QQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNL 520
P Q P AP +P QQ AL +PH +P L Q L
Sbjct: 783 QAPNQ-----PQAPTAPVPHTHIQQAPALHPQ------RPPSPHPPPHPSPHPPL--QPL 829
Query: 521 AGPLSLGPVLAPH--------SGAHSAHILSAAPI--QVGQPALFQMPVSLAAGSLPTQS 570
G S G AP G H L A P+ G P F +P + G P +
Sbjct: 830 TG--SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT 887
Query: 571 QPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA-AATGEAAPVLTVQ----PAP 625
PA A P + + LP S A+ + QP PA A P T PAP
Sbjct: 888 SPAAAYPHTS-----LQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942
Query: 626 QA---PPAVSTPLPLGLQQPQAQQPPQAP--------TPQAAAPPQATTPQPSPGLASSP 674
QA PP +S P P + P P P A PP PQ P L SSP
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP-LPSSP 1001
Query: 675 EKIVLGQPPSAT-------PTAILTQDSLQMFLPQER-SQQPLSAEGPHLSVPASVIVSA 726
QPP T P A L PQ +Q P GP P + ++
Sbjct: 1002 -----AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056
Query: 727 PPPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPL 785
PPA A P GA G + P P QI A P S P
Sbjct: 1057 TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-------- 1108
Query: 786 GDSPHLPSPHPT 797
P PSP PT
Sbjct: 1109 -PPPRSPSPEPT 1119
Score = 67.8 bits (164), Expect = 8e-11
Identities = 123/440 (27%), Positives = 152/440 (34%), Gaps = 76/440 (17%)
Query: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKP 370
G AP+ P G P PG P P+ T P Q P P Q P
Sbjct: 746 GVTPAPSSAPPGTPQLPTPG-------PTPSA----TAVPPQGSPTASQAPNQPQ---AP 791
Query: 371 FAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPAT 430
AP T IQ P PQ+P +P P P + QP
Sbjct: 792 TAPVPHT-HIQQAPALHPQRPPSPH-------------------PPPHPSPHPPLQP--L 829
Query: 431 TTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAP-AVQLPQQLSAL 489
T A P P P L QG P H L PG P LP Q S
Sbjct: 830 TGSAGQPSAPSHAQPP----LHGQGP----PGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 490 PANVGGQILAAAAPHTGGQLIAN-PILTNQN--LAGPLSLGPVLAPHSGAHSAHILSAAP 546
A +G AAA PHT QL A+ L +Q PL P+ PH P
Sbjct: 882 QAPLGTS-PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP-----PTTP 935
Query: 547 I-QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT-LPPSAVAMLNTPDGLVQ 604
I Q+ P + P L+ S + + P PA + T PPSA + P +
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA----HPPPLQLM 991
Query: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664
P + + A P Q PP S P P GL Q A QPP A P P TP
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQ-VAPQPPFAQHPFVPGGPPPITP 1049
Query: 665 QPSPGLASSPE-KIVLGQPP----SATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
P ++ P QPP +A+ +I S + Q + + AE P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE---- 1105
Query: 720 ASVIVSAPPPAQDPAPATPV 739
S PPP + P+P V
Sbjct: 1106 -----SPPPPPRSPSPEPTV 1120
Score = 42.7 bits (99), Expect = 0.003
Identities = 105/459 (22%), Positives = 150/459 (32%), Gaps = 67/459 (14%)
Query: 1126 SPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPS-AEMVMIDRMFIQEEK 1184
SP +K E T+ RT + K + E SR SPS E D + +E
Sbjct: 642 SPLKSNKRQREKVASDTEEADRTSSKKTKTQ----EISRPNSPSEGEGESSDSRSVNDEG 697
Query: 1185 TTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSS----APGASTQPP- 1239
++ D + S + +S++ L P + P S+ PP
Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757
Query: 1240 -PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSS-----SAASSLDADEDGPMPSRN 1293
P LPT G +PS T S ++S + + +A + P
Sbjct: 758 TPQLPTP--------GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809
Query: 1294 RPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVH-QPPPPPATLKVAEPPPRPPPP 1352
RPP L+ + + A P+H Q PP P +L+ A P + P P
Sbjct: 810 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ-AGPLLQHPGP 868
Query: 1353 PPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGG 1412
P P G PP A+ + PLGT+P T + A + R +
Sbjct: 869 PQPFGL-------PPQASQGQAPLGTSPAAA---YPHTSLQLPASQSALQSQQPPREQPL 918
Query: 1413 SPAPLPAK-VDEATSGLIRELAAVEDELYQRMLKGP---------PPEPAASAAQGTGDP 1462
PAPL + + I +L A + + L GP PP PA
Sbjct: 919 PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 978
Query: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP--- 1519
+ PP + P S Q LT+ NL P P
Sbjct: 979 HPPSAHPPPLQLMPQSQP------LPSSPAQPPGLTQSQ--------NLPPPPASHPPTG 1024
Query: 1520 ----APSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLG 1554
AP P A P PPP+ P S+ G G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063
Score = 41.2 bits (95), Expect = 0.008
Identities = 79/309 (25%), Positives = 97/309 (31%), Gaps = 77/309 (24%)
Query: 1207 SLGLPIAASSEGHRLPGHGPLS----SSAPGASTQPPPH---LPTKLVIRHGGAGGSPSV 1259
S G P A S L G GP + P PP LP + G SP+
Sbjct: 832 SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891
Query: 1260 TWARASSSLSSSSSSSSAASSLDADEDGP-------MPSRNRPPIKTYEARSRIGLKLKI 1312
+ S L +S S A S + P MP PP
Sbjct: 892 AYPHTSLQLPASQS---ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948
Query: 1313 KQEAGLSKVVHNTALDP-----------VHQPP---PPPATL---------KVAEPP--- 1346
+G S N L P H PP PPP L A+PP
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 1008
Query: 1347 -----PRPPPPPPPTGQMNGTVDHPP----PAAPERKPLGTAPHCPRLPLRKTYRENVGG 1397
P PP PPTG ++ PP P P P T P CP + G
Sbjct: 1009 QSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP------STSTPPAG 1061
Query: 1398 PGAPEGTP-------AGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE 1450
PG P G GGS PLP + I+E A + E + PPP
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLP-------TVQIKEEALDDAE----EPESPPPP 1110
Query: 1451 PAASAAQGT 1459
P + + + T
Sbjct: 1111 PRSPSPEPT 1119
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 105 bits (263), Expect = 3e-22
Identities = 159/623 (25%), Positives = 217/623 (34%), Gaps = 109/623 (17%)
Query: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHS-GA 536
P P +P + G LA+ + L A P+L N LA ++ P + P S
Sbjct: 594 PTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNL 653
Query: 537 HSAHILSAAPIQVGQPALFQMPVSLA-AGSLPTQSQPA-PAGPAATTVLQGVTLPPSAVA 594
+ + P V + +P L + +S+P P A ++ L G SA
Sbjct: 654 PPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGG-----SAPQ 708
Query: 595 MLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGL-------QQPQAQQP 647
+L + L P T E L ++ A + P PL L QQ QA+
Sbjct: 709 LLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETE 768
Query: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707
++P P P + P+ GLA P ++ P A TA+ +RS
Sbjct: 769 ERSPQPPTGKWP--SLPETPTGLADIPCLVI--PPAPAKKTAL------------QRS-- 810
Query: 708 PLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAP 767
P + ++ P PA P+P PV+K P P+ ++P A
Sbjct: 811 ------PETPLEICLVPVGPSPAS-PSPEPPVSKPVASSP------TEQVPSQEMPLLAR 857
Query: 768 LKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL-------- 819
P S SP++P + + P+ PPS PP Q S P S P+
Sbjct: 858 PSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHY 917
Query: 820 ----------------HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP--- 860
+PC PP PPT+P + VPP S P P P P
Sbjct: 918 APLPSWPCYPHVSPSGYPCLPP--PPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSS 975
Query: 861 -----PL----RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
PL PQ P +PP P LPP+S AV S PA P
Sbjct: 976 TCTYGPLGWGPGPQHAPFWSTVPPPP-LPPASIGRAVPQPKMESRGTPAG---------P 1025
Query: 912 PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGII 971
P S PP +L L P AP P + + P PA P PK + Q P
Sbjct: 1026 PENVLPLSMAPPLSLGL-PGHGAPQTEPTK---VEVKPVPASPHPKHKVSALVQSPQMKA 1081
Query: 972 LQ-NKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL 1030
L A G S L P T P P P+ P P +T P
Sbjct: 1082 LACVSAEGVTVEEPASERLKPETQET--------RPREKPPLPATKAVPTPRQST--VPK 1131
Query: 1031 LPAENKAFASNLPTLNVAKAASS 1053
LPA + A L L + S
Sbjct: 1132 LPAVHPARLRKLSFLPTPRTQGS 1154
Score = 79.7 bits (195), Expect = 2e-14
Identities = 223/918 (24%), Positives = 299/918 (32%), Gaps = 229/918 (24%)
Query: 114 TEQTLEAEAELDLGPFQLPTLQPADG-GAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGP 172
T QT L L + P D A PT G V AGP + PG DL
Sbjct: 564 TIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAS---- 616
Query: 173 PTVLTHQALVPPQDVVNKALSVQPFL-QPVGLGNVTLQP--IPGLQGLP--NGSPGGATA 227
T LV P L +P L PV + + P +P LP + P G
Sbjct: 617 ----TSSELVEP-------LPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAP 665
Query: 228 ATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVS---GYLASAAGPSEPVTLASAGVSPQG 284
L L PV TP +L K P G ++SA G S P L +
Sbjct: 666 VDLALV------DPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLV------ES 713
Query: 285 AGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVA---------------- 328
L K + V ++ + G SA T +PL+++
Sbjct: 714 ESLDPPKTIIPEVKEVVDSLKIESGT---SATTHEARPRPLSLSEYRRRRQQRQAETEER 770
Query: 329 ---PGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPG 385
P G P +P TPT + P V+PP APA T
Sbjct: 771 SPQPPTGKWPSLP-------ETPTGLADIPCLVIPP----------APAKKT-------- 805
Query: 386 ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSK 445
AL + P+ P + + G P+PA + P+PP +SK
Sbjct: 806 ALQRSPETPLEICLVPVG-----------PSPA---------------SPSPEPP--VSK 837
Query: 446 PMSVHLLNQGSSIVIPAQHM--LPGQNQFLLPGAPAVQLPQQLSA-LPANVGGQILAAAA 502
P++ Q +P+Q M L + + +PAV P +SA LP GG + +
Sbjct: 838 PVASSPTEQ-----VPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSL 892
Query: 503 PHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILS------------------- 543
P P L +L PLS+GPVL P H A + S
Sbjct: 893 PP--------PPLQPPSL--PLSMGPVL-PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPP 941
Query: 544 AAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL----PPSAVAMLNTP 599
P+ G P + +P + S+P PAP P ++T G P A P
Sbjct: 942 TVPLVSGTPGAYAVPPTC---SVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVP 998
Query: 600 DGLVQPATPAAATGEAAPVLTVQP--APQAPPAVSTPL----PLGLQQPQAQQPPQAPTP 653
P P A+ G A P ++ P PP PL PL L P P PT
Sbjct: 999 P----PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTK 1054
Query: 654 QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713
P A+ P P +++ L Q P A ++ + + + P +P + E
Sbjct: 1055 VEVKPVPAS-PHPKHKVSA------LVQSPQMKALACVSAEGVTVEEPASERLKPETQET 1107
Query: 714 -PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ-----IPAAAP 767
P P + P P Q P P A L + P P Q + A
Sbjct: 1108 RPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLS----FLPTPRTQGSEDVVQAFIS 1163
Query: 768 LKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQA 827
G S SL Q ++ P P S V P + PL P+
Sbjct: 1164 EIGIEASDLSSLLEQFEKSEAKK-ECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPE- 1221
Query: 828 PPTLPGIFVIQNQLGVPPPASNPAP-----TAPGPPQPPLRPQSQPPEGPLPP-----AP 877
+ N G+ PPA+ P A P+S EG L P A
Sbjct: 1222 ---------LANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAK 1272
Query: 878 HLPPSSTSSAVASSSETS-----------SRLPAPTPSDFQLQFPPSQGP------HKSP 920
H V S SR P P P G H+
Sbjct: 1273 HPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTP---PKKMPALVIPEVGSRWNVKRHQDI 1329
Query: 921 TPPPTLHLVPEPAAPPPP 938
T P L L PAAPPPP
Sbjct: 1330 TIKPVLSL--GPAAPPPP 1345
Score = 74.7 bits (182), Expect = 6e-13
Identities = 131/528 (24%), Positives = 177/528 (33%), Gaps = 89/528 (16%)
Query: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP 668
AAA ++P + A Q+ PA PL L + Q PT + +P P
Sbjct: 529 AAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVD 588
Query: 669 GLASSPEKI--VLGQPPSATPTAI---LTQDSLQMFLPQERSQ-QPLSAEGPHLSVPASV 722
+ + P + VL P P + T L LP E P+ A+ + PA V
Sbjct: 589 SVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVD-PAVV 647
Query: 723 IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA-----PQIPAAAPLKGPGPSSSP 777
+S P D P+ P L P+ P P P + S+P
Sbjct: 648 PISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAP 707
Query: 778 SLPHQAPLGDSPHLPSP-------------------HPTRPPSRPPS----RPQSVSRPP 814
L ++ D P P H RP RP S R + R
Sbjct: 708 QLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARP--RPLSLSEYRRRRQQRQA 765
Query: 815 SEPPLHPCPP----PQAPPTLPGIFVIQNQLGVPPPAS-------------------NPA 851
P PP P P T G+ I + P PA P+
Sbjct: 766 ETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPS 825
Query: 852 PTAPGPPQPPLRPQSQPP-------EGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
P +P P P +P + P E PL P P S S AV + S+ LP P
Sbjct: 826 PASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGG 885
Query: 905 DFQLQFPPSQGPHKSPTPPPTLHL-----VPEP---AAPPPPPPRTFQMVTTPFPALPQP 956
L PPS P P PP+L L +P+P AP P P + + +P LP P
Sbjct: 886 ---LGMPPSLPP--PPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPP 940
Query: 957 KAL-----LERFHQVPSGIILQNKAGGAPAAPQTST-SLGPL---TSPAASVLVSGQAPS 1007
+ + VP + AP +P +ST + GPL P + S P
Sbjct: 941 PTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPP 1000
Query: 1008 GTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
P A P P + P P EN S P L++ P
Sbjct: 1001 PLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
Score = 33.1 bits (74), Expect = 2.2
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 1228 SSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDG 1287
SSS + + PPH K R + S + +SSS SSSSSSSS++SS +
Sbjct: 1449 SSSRSRSRSLSPPH---KRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRS 1505
Query: 1288 PMPSRNRPPIKTYEA 1302
P P R + Y +
Sbjct: 1506 PSPRRRSDRRRRYSS 1520
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 105 bits (261), Expect = 4e-22
Identities = 139/523 (26%), Positives = 184/523 (35%), Gaps = 61/523 (11%)
Query: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGL-VQPATPAAATGEAAPVLTVQP-- 623
P S PA T G LP + +TP G + TP A G+ P L
Sbjct: 915 PGSSSPAIRRLPDTGSKDGYKLPWT----WDTPSGRGLAEGTPTA--GKLGPTLGAGTTR 968
Query: 624 APQAPPAVSTPLPLGL-QQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP 682
+P +PP + G ++P ++ P P APP TP P P + P L
Sbjct: 969 SPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPP---TPSPGPSASPGPPGPALTSD 1025
Query: 683 PS--ATPTAILTQDSLQMFL--------PQERSQQPLSAEGPH--LSVPASVIVSAPPPA 730
S TP + LT ++ P R+ L P LS P S +V A P
Sbjct: 1026 SSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPE 1085
Query: 731 QDPAPATPVAKGAGLGPQAPDSQASPAP-APQIPAAAPLKGPGPSSSPSLPHQAPLGDSP 789
P P + K P P S +P + Q+P + P ++P + SP
Sbjct: 1086 PSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTT--PDLDTTPYSSTVSEYSRSP 1143
Query: 790 H-LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848
PSPHPT P + + P+ P P P P T P I + +P P +
Sbjct: 1144 DPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTP--HPTTTPHPTTITHSTMIPDPTT 1201
Query: 849 NPAP-----TAPGPPQPPLRPQ----SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899
P P + P P PQ QP P PH P++T + T P
Sbjct: 1202 TPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPH--PTTTPHPTTITHSTMIPDP 1259
Query: 900 APTPSDFQLQFP-----PSQGPHKSPTPPPTL----HLVPEPAAPPPP-----PPRTFQM 945
TP F P P+ PH + TP PT P P P P P T
Sbjct: 1260 TTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDP 1319
Query: 946 VTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGP---LTSPAASVLVS 1002
TTP P P P + V L + AP SL P T+PA S
Sbjct: 1320 TTTPHPTTPDPSS-TPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTS 1378
Query: 1003 GQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL 1045
Q P+ P+ + AT + PL + K S P L
Sbjct: 1379 -QIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNL 1420
Score = 89.7 bits (221), Expect = 2e-17
Identities = 124/529 (23%), Positives = 179/529 (33%), Gaps = 115/529 (21%)
Query: 570 SQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGL-VQPATPAAAT---------------- 612
+ P P GPA T+ P SA+ T D P TP A+
Sbjct: 1013 ASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALS 1072
Query: 613 ---GEAAPVLTVQPAPQAPPAV--------STPLPLGLQQPQAQQPPQAPT-PQAAAPPQ 660
P LT +P+P P + STP + P ++Q P++ T P P
Sbjct: 1073 TPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPY 1132
Query: 661 ATT-------PQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713
++T P PSP SP P+ TP + D + P P
Sbjct: 1133 SSTVSEYSRSPDPSP----SPH-------PTTTPDPTMAPDPITTLNPTVTPHFP----- 1176
Query: 714 PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGP 773
+ P P P P T PD +P P I + + P
Sbjct: 1177 -----------TTPHPTTTPHPTTITHS-----TMIPDPTTTPQPFTTITHSTMIPDPTT 1220
Query: 774 SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPG 833
+ P Q +PH +PHPT P P +++ P P T P
Sbjct: 1221 TPQPFTTMQPTT--TPHSTTPHPTTTP-----HPTTITHSTMIPD---------PTTTPQ 1264
Query: 834 IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSE 893
F +P P + P PT P P + P P P +T+ ++
Sbjct: 1265 PFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPH 1324
Query: 894 TSSRLPAPTPSDFQLQFPPSQG-----PHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTT 948
++ P+ TP + P S G P +PT P+LH P+ P P + T+
Sbjct: 1325 PTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLH--PQLTFTAPAPHTS----TS 1378
Query: 949 PFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSG 1008
P L +P LE +P+ T+TS+ PL++ S Q+P+
Sbjct: 1379 QIPTL-EPSPALE----------------SSPSRSSTATSMDPLSTEDFKPPRS-QSPNL 1420
Query: 1009 TPTAPSHAPAPAPMAATGLPPLL-PAENKAFASNLPTLNVAKAASSGPG 1056
TP P+H P A PLL P + L L + PG
Sbjct: 1421 TP-PPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPG 1468
Score = 75.5 bits (184), Expect = 4e-13
Identities = 103/425 (24%), Positives = 149/425 (35%), Gaps = 58/425 (13%)
Query: 552 PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT--LPPSAVAMLNTPDGLVQPATPA 609
PAL P +LP + P+ P+ T L + +P S TPD P +
Sbjct: 1080 PALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDT----TPDLDTTPYSST 1135
Query: 610 AATGEAAPVLTVQPAP-------QAPPAVSTPLPLGLQQ-PQAQQPPQAPTPQAAA---- 657
+ +P + P P AP ++T P P P P P
Sbjct: 1136 VSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTM 1195
Query: 658 -PPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
P TTPQP + S + P+ TP T P + P + P
Sbjct: 1196 IPDPTTTPQPFTTITHS----TMIPDPTTTPQPFTTMQPTTT--PHSTTPHPTTTPHPTT 1249
Query: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA---PDSQASPAPAPQIPAAA-PLKGPG 772
+++I P P P P T + P P + P P P P
Sbjct: 1250 ITHSTMI---PDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPD 1306
Query: 773 PSSSPSLPHQAPLGDSPHLPSPHPTRPP-----SRPPSRPQSVSRPPSEPPLHPCPPPQA 827
P+++P +PH +P P+ P S P S +S P P + P PQ
Sbjct: 1307 PTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQL 1366
Query: 828 PPTLPGIFVIQNQLGV--PPPA--SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSS 883
T P +Q+ P PA S+P+ ++ PL + P P +P+L P
Sbjct: 1367 TFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKP--PRSQSPNLTPPP 1424
Query: 884 TSSAVASSSETSSRLPAPTPSDFQLQFPP------------SQGPHK---SPTPPPTLHL 928
T + ++S T S P +P+ L PP S GPH +PTPP +
Sbjct: 1425 THTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMA 1484
Query: 929 VPEPA 933
PA
Sbjct: 1485 CEPPA 1489
Score = 68.6 bits (166), Expect = 5e-11
Identities = 114/499 (22%), Positives = 157/499 (31%), Gaps = 66/499 (13%)
Query: 426 QPPATTTGAAPPQP-PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
+P AT T P P P A P L + S + P + +P P
Sbjct: 996 RPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPA 1055
Query: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSA 544
+ + A + P + P LT + PL P + + + S
Sbjct: 1056 SRTNPDLILTSPDFALSTPDSS----VVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSL 1111
Query: 545 API--QVGQ----PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNT 598
+P QV + P L P S P+P+ TT T+ P + LN
Sbjct: 1112 SPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTT--PDPTMAPDPITTLNP 1169
Query: 599 -----------PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP 647
P P T +T P T QP + P P QP
Sbjct: 1170 TVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQ 1229
Query: 648 PQAPTPQAAAPPQATTPQPS--------PGLASSPEKIVLGQP-----PSATPTAILTQD 694
P TP + P TTP P+ P ++P+ QP P+ TP T
Sbjct: 1230 PTT-TPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPH 1288
Query: 695 SLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATP----------VAKGAG 744
P ++ + P + P P P P TP V+
Sbjct: 1289 PTTTPHPTTTPHPTMTPDPTTTPYPTTT----PDPTTTPHPTTPDPSSTPVITTVSLPTS 1344
Query: 745 LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAP-LGDSPHLPSPHPTRPPSRP 803
LG + +P P + P P +S S Q P L SP L S P+R +
Sbjct: 1345 LGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTS---QIPTLEPSPALESS-PSRSSTAT 1400
Query: 804 PSRPQSVS--RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861
P S +PP + PPP P + P P +P TA PP
Sbjct: 1401 SMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVS-----PDPLLSP--TAHPLDHPP 1453
Query: 862 LRPQSQPPEGPLPPAPHLP 880
L P + P P PH P
Sbjct: 1454 LDPLTLGPTPGQSPGPHGP 1472
Score = 48.5 bits (114), Expect = 5e-05
Identities = 111/424 (26%), Positives = 148/424 (34%), Gaps = 89/424 (20%)
Query: 630 AVSTPLPLGLQQPQAQQPPQAPTP-QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPT 688
AV +PLG P A TP +AA+ P +T +PG A PP A+PT
Sbjct: 401 AVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGV-------SPPPASPT 453
Query: 689 AILTQDSLQMFLPQERSQQPLSAEGPHLSV-PASVIVSAPPPAQDPAPATPVAKGAGLG- 746
+L + + PQ R S L V + + D + V + G G
Sbjct: 454 -VLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGG 512
Query: 747 PQAPDSQASPAPAPQIPAAAPLK-GPGP---SSSPSLPHQAPLGDSPHLP-SPHP----- 796
PQ PD PAA G GP + +A L D P P H
Sbjct: 513 PQQPD-----------PAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNE 561
Query: 797 ------TRPPSRPP-SRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG---VPPP 846
T PP S P S S P P T P V + L P
Sbjct: 562 DVGVTCTGPPGLDSISDPFSWSWIPGLGRDRDAWLPGELATKPSASVTASVLEKTTTKAP 621
Query: 847 ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL----PPSSTSSAVASSSETSSRLPAPT 902
P T + RP +QPP +P H PP TS A+ + +SR P
Sbjct: 622 GKMPKSTKKWVTKNAKRPTTQPPV--MPTTKHSRAQSPPDLTSQTTAALTTEASRRPT-- 677
Query: 903 PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLER 962
S+F + P ++ P + T T L P+ AP +T M+TT
Sbjct: 678 -SEFTRR-PTTEAPQRW-TSHTTATLTPQ--APRERTTKTMAMLTTQ------------- 719
Query: 963 FHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS-PAASVLVSGQAPSGTPTAPSHAPAPAP 1021
PQ TS + S P AS+ S + P G+P +P PAP+P
Sbjct: 720 -------------------GPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKD-PAPSP 759
Query: 1022 MAAT 1025
+T
Sbjct: 760 SVST 763
Score = 47.8 bits (112), Expect = 8e-05
Identities = 119/571 (20%), Positives = 182/571 (31%), Gaps = 76/571 (13%)
Query: 212 PGLQGLPNGSP-GGATAATLGLAPIQVVGQPVMA-----LNTPTSQLLAKQVPVSGYLAS 265
P +GL G+P G TLG + G P +P ++ P A+
Sbjct: 943 PSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPA--AT 1000
Query: 266 AAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQP- 324
P P SA P G L + + L + A S PT P+ +
Sbjct: 1001 RTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEAT-SDAPDTSPPTPDPASRTN 1059
Query: 325 ---LAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQ--LTPKPFAPAGATLT 379
+ +P S P +V+ TP P P P LP +L TP T
Sbjct: 1060 PDLILTSPDFALS--TPDSSVVPALTPEP-SPTPLPTLPKELTSDPSTPSEVTSLSPTSE 1116
Query: 380 IQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQP 439
E P P + T ++ + S P + P T P
Sbjct: 1117 QVPESDTTPDLDTTPYSSTVSEYSRS-PDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHF 1175
Query: 440 PGALSKPMSVHLLNQGSSIVIPAQHMLPGQ-----NQFLLPGAPAVQLP---QQLSALPA 491
P + H S +IP P + ++P P Q + P
Sbjct: 1176 PTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPH 1235
Query: 492 NVGGQILAAAAPH----TGGQLIANPILTNQNLAG--PLSLG-PVLAPHSGAHSAHILSA 544
+ PH T +I +P T Q P ++ P PH +
Sbjct: 1236 STTPH--PTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTP 1293
Query: 545 APIQVGQPALFQMPVSLAAGSLP----TQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD 600
P P + P + + T P P++T V+ V+LP S L++P
Sbjct: 1294 HPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPT 1353
Query: 601 --GLVQPA---------------TPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ 643
V+P+ T T E +P L P+ + PL +
Sbjct: 1354 LAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPL-----STE 1408
Query: 644 AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703
+PP++ +P PP TP + L SP+ ++ P+A P D L +
Sbjct: 1409 DFKPPRSQSPN-LTPPPTHTPHSASDLTVSPDPLL---SPTAHPLDHPPLDPLTL----- 1459
Query: 704 RSQQPLSAEGPH----LSVPASVIVSAPPPA 730
P + GPH P +++ PPA
Sbjct: 1460 -GPTPGQSPGPHGPCVAPTPPVRVMACEPPA 1489
Score = 44.3 bits (103), Expect = 0.001
Identities = 131/599 (21%), Positives = 194/599 (32%), Gaps = 113/599 (18%)
Query: 967 PSGIILQNKAGGAPAAPQTSTSLGPLT--SPAASVLVSGQAPSGTPTAPSHAPAPAPMAA 1024
PSG + A G P A + +LG T SP + + +G+P P P AA
Sbjct: 943 PSG---RGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAA 999
Query: 1025 TGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK-KPPTLQPSKEAC 1083
T P P+ + + P + +S S L E+ PPT P+
Sbjct: 1000 TRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRT- 1058
Query: 1084 FLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQ 1143
+ PD+ + P + L P PSP+ + +E + +
Sbjct: 1059 ------NPDLILTSPDFALSTPD-SSVVPALTPE-------PSPTPLPTLPKELTSDPST 1104
Query: 1144 LLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVS 1203
+ T +SP++E V E TT LD EY
Sbjct: 1105 PSEVTS----------------LSPTSEQV-------PESDTTPDLDTTPYSSTVSEYSR 1141
Query: 1204 SSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP--PHLPTKLVIRHGGAGGSPSVTW 1261
S P H P + P + P PH PT +P T
Sbjct: 1142 SPDPSPSP-------HPTTTPDPTMAPDPITTLNPTVTPHFPTT-----PHPTTTPHPTT 1189
Query: 1262 ARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKV 1321
S+ + +++ +++ P P+ P T + +
Sbjct: 1190 ITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTT----------------T 1233
Query: 1322 VHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHP-----PPAAPERKPL 1376
H+T P P P T P P P P T Q T+ HP P P
Sbjct: 1234 PHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPT-TMPHPTTTPHPTTTPHPTTT 1292
Query: 1377 G---TAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELA 1433
T PH P T P P TP S P+ V TS L EL+
Sbjct: 1293 PHPTTTPHPTMTPDPTTTPYPTTTPD-PTTTPHPTTPDPSSTPVITTVSLPTS-LGTELS 1350
Query: 1434 A------VEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASF 1487
+ V+ L+ ++ P +++ T +P +P L + R S + +D S
Sbjct: 1351 SPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEP---SPALESSPSRSSTATSMDPLST 1407
Query: 1488 SSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSY-PHAASAGTPASPPPLHRPEAYP 1545
P Q+P TP P++ PH+AS T SP PL P A+P
Sbjct: 1408 EDFKPPRS-----------------QSPNLTPPPTHTPHSASDLT-VSPDPLLSPTAHP 1448
Score = 37.7 bits (86), Expect = 0.087
Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 17/137 (12%)
Query: 629 PAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPT 688
P P+ + +AQ PP + AA + +P+ P + S T T
Sbjct: 639 PTTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHT-T 697
Query: 689 AILTQDSLQMFLPQERSQQP---LSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
A LT + P+ER+ + L+ +GP S I S P + +P+ P
Sbjct: 698 ATLTPQA-----PRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEG----- 747
Query: 746 GPQAPDSQASPAPAPQI 762
+P+S PAP+P +
Sbjct: 748 ---SPESPKDPAPSPSV 761
Score = 35.8 bits (81), Expect = 0.33
Identities = 59/242 (24%), Positives = 79/242 (32%), Gaps = 48/242 (19%)
Query: 1334 PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRE 1393
PP PA + A P P P P P P PA PH L
Sbjct: 994 PPRPAATRTAPPTPSPGPSASP--------GPPGPALTSDSSRELTPHS---ALTSEATS 1042
Query: 1394 NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA 1453
+ P PA R +P + D A L+ + + + P P P
Sbjct: 1043 DAPDTSPPTPDPASRT---NPDLILTSPDFA-------LSTPDSSVVPALTPEPSPTPLP 1092
Query: 1454 SAAQG-TGDPDW--EAPGLPPAKRRKSES---PDVDQASFSSD------SPQDD-----T 1496
+ + T DP E L P + ES PD+D +SS SP T
Sbjct: 1093 TLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPT 1152
Query: 1497 LTEHLQSAIDSILNLQQAPGRTP-APSYPHAASAGTPAS-------PPPLHRPEAYPPSS 1548
T A D I L P TP P+ PH + P + P P P+ + +
Sbjct: 1153 TTPDPTMAPDPITTLN--PTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTIT 1210
Query: 1549 HN 1550
H+
Sbjct: 1211 HS 1212
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 102 bits (255), Expect = 2e-21
Identities = 155/560 (27%), Positives = 213/560 (38%), Gaps = 153/560 (27%)
Query: 577 PAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT-GEAAPV----------LTVQPAP 625
P T + + V P+ V L++ G+ + T AT G PV + PAP
Sbjct: 143 PLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAP 202
Query: 626 QAPPAV-STPLPLGLQQPQAQQPP---QAPTPQAAAPP---QATTPQPSPGLASSPEKIV 678
PPA S +P + P A Q P AP P + P + P PSP LA P
Sbjct: 203 ICPPAPGSASVPHSV--PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVP---A 257
Query: 679 LGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATP 738
L P + PT I ++ LSV ASV+V P PA P
Sbjct: 258 LAPAPPSVPTLI--------------------SDSNPLSVSASVLV--PVPASAP----- 290
Query: 739 VAKGAGLGPQAPDSQASPAPAP-QIPAAAP----LKGPGPSSSPSLPHQAPLGDSPHLPS 793
P P ++PAPAP +P +AP ++ P P S+P+L P
Sbjct: 291 --------PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLA---------PV 333
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P P P P S P + PPS P P P PP+ P + PA P P
Sbjct: 334 PTPVLAPM-PASTPPAAPAPPSVPMPTPTPS-SGPPSTPTLI----------PAFAPTP- 380
Query: 854 APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ---F 910
P P P+ PAP P++T +A+ +S AP P+ F L F
Sbjct: 381 VPAPTPAPI----------FTPAPTPMPAATPAAIPTS--------APIPASFSLSRVCF 422
Query: 911 PPSQGPHKSPTP----PPTLHLVPEPAAPPPPP-----------PRTFQMVTT-PFPALP 954
P +Q P P P T+ +P PPP P T + +T P LP
Sbjct: 423 PAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
Query: 955 ---QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQ-----AP 1006
Q + L G++ + P A + PLTS + V + +P
Sbjct: 483 SYLQDRCL--------PGVLASPELRSYPYAFSVAR---PLTSDSKLVSLEVNRLPCTSP 531
Query: 1007 SG-TPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP---GKPSGLQ 1062
SG T T P+ P P+A T L+ A K + P L +S+ P PSG +
Sbjct: 532 SGSTTTQPAPDGVPGPLADTS---LVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTE 588
Query: 1063 YESK-----LSGLKKPPTLQ 1077
+++ S LK PP L+
Sbjct: 589 QQTEGTSVTFSPLKSPPQLE 608
Score = 84.3 bits (207), Expect = 8e-16
Identities = 140/519 (26%), Positives = 191/519 (36%), Gaps = 83/519 (15%)
Query: 523 PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQP-------APA 575
P + G PHS + + + P V L +PV +A S+P S P APA
Sbjct: 205 PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL--VPVQVAT-SVPAPSPPLAPVPALAPA 261
Query: 576 GPAATTVLQ---------GVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP- 625
P+ T++ V +P A A + P L PA + +AP L + AP
Sbjct: 262 PPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPV 321
Query: 626 --QAPPAVSTPLPLGLQQPQ-AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP 682
AP V P+P + P A PP AP P + P TP PS G S+P I
Sbjct: 322 PPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMP---TPTPSSGPPSTPTLI----- 373
Query: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD-------PAP 735
P+ PT + +F P + P+ A + PA++ SAP PA PA
Sbjct: 374 PAFAPTPVPAPTPAPIFTP---APTPMPA-----ATPAAIPTSAPIPASFSLSRVCFPAA 425
Query: 736 ATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDS---PHLP 792
P + L Q P IP P P S +LP + + P LP
Sbjct: 426 QAPAMQKVPLSFQPGTVLTPSQPLVYIP---PPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
Query: 793 SPHPTR--------PPSRPPSRPQSVSRP-PSEPPLHPCPPPQAPPTLPGIFVIQNQL-- 841
S R P R SV+RP S+ L + P T P
Sbjct: 483 SYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPD 542
Query: 842 GVPPP-ASNPAPTAPGPPQPPLRPQSQPPEGP-LPPAPHLPPSSTSSAVASSSETSSRLP 899
GVP P A TA P +P P G PP P PS T +S T S L
Sbjct: 543 GVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLK 602
Query: 900 APTPSDFQLQFPP--SQGPHKSPTPPPTLHL-VPEPAAPPPPPPRTFQMVTTPFPALPQP 956
+P + ++ PP S+ P + L +P PP P T P
Sbjct: 603 SPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLT--------PVHTSS 654
Query: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP 995
KALL S ++ +++ A ++ LG +SP
Sbjct: 655 KALL-------STVLSRSQRTTQAAGGNVTSCLGSTSSP 686
Score = 72.8 bits (177), Expect = 2e-12
Identities = 134/564 (23%), Positives = 188/564 (33%), Gaps = 111/564 (19%)
Query: 349 TPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQN 408
T P PA + PP AP A++ P ++P + P ++
Sbjct: 194 TNFSPLPAPICPP----------APGSASV-----PHSVPDAFQVPLSVPAPVPHSGLVP 238
Query: 409 V-VLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLP 467
V V + PAP+ PP A P PP + + L+ +S+++P P
Sbjct: 239 VQVATSVPAPS--------PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAP 290
Query: 468 GQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG 527
L L +SA P ++ A P + L+ P+ T
Sbjct: 291 PSGPVPLSAPAPAPLSVPVSAPPL----ALIQAPVPPSAPTLVLAPVPT----------- 335
Query: 528 PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT 587
PVLAP + ++ P P MP PT S P+ P
Sbjct: 336 PVLAP--------MPASTPPAAPAPPSVPMPT-------PTPSSGPPSTPTLIPAFAPTP 380
Query: 588 LPPSAVAMLNTPDGLVQPATPAAATGEAAPV-------LTVQPAPQAPPAVSTPLPLGLQ 640
+P A + TP PA AA +AP+ PA QAP PL
Sbjct: 381 VPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSF--- 437
Query: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFL 700
QP TP + P P PS G S V P + ++ LT L +L
Sbjct: 438 -----QPGTVLTP---SQPLVYIPPPSCGQPLS----VATLPTTLGVSSTLTLPVLPSYL 485
Query: 701 PQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAP 760
Q+R + A S P + V+ P + + V + L +P + PAP
Sbjct: 486 -QDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNR---LPCTSPSGSTTTQPAP 541
Query: 761 QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH 820
PGP + SL + LP+P P P P S PP H
Sbjct: 542 D-------GVPGPLADTSL----VTASAKVLPTPQPLLP------APSGSSAPP-----H 579
Query: 821 PCPPPQ-APPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ--------PPEG 871
P P G V + L PP + P + PL S+ P +
Sbjct: 580 PAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQR 639
Query: 872 PLPPAPHLPPSSTSSAVASSSETS 895
PP P L P TSS S+ S
Sbjct: 640 KTPPMPVLTPVHTSSKALLSTVLS 663
Score = 40.8 bits (94), Expect = 0.010
Identities = 93/383 (24%), Positives = 137/383 (35%), Gaps = 54/383 (14%)
Query: 129 FQLPTLQPAD---GGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQ 185
FQ+P PA G P + + P A P PP+V T + P
Sbjct: 221 FQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAP-----APPSVPTLISDSNPL 275
Query: 186 DVVNKALSVQPFLQPVGLGNVTLQ-PIPGLQGLPNGSPGGA--------TAATLGLAPIQ 236
V L P P G V L P P +P +P A +A TL LAP+
Sbjct: 276 SVSASVLVPVPASAPPS-GPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVP 334
Query: 237 VVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAA 296
M +TP + VP+ S+ PS P + + +P + A
Sbjct: 335 TPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTP------VPAPTPAP 388
Query: 297 VATTLNGNSVFGGAGAASAPTGTPSGQ---------PLAVAPGLGSSPLVPAPNVILHRT 347
+ T + A A+ PT P P A AP + PL P +L
Sbjct: 389 IFTP--APTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVL--- 443
Query: 348 PTPIQPKPAGVLPPKLYQLTPKPFAP----AGATLTIQGEPG-----ALPQQPKAPQNLT 398
TP QP + PP Q P +TLT+ P LP +P+ +
Sbjct: 444 -TPSQPL-VYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRS 501
Query: 399 FMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQP-PGALSKPMSVHLLNQGSS 457
+ A + + S +L+ N + P + +G+ QP P + P++ L S+
Sbjct: 502 YPYAFSVARPLT-SDSKLVSLEVN--RLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASA 558
Query: 458 IVIPA-QHMLPGQNQFLLPGAPA 479
V+P Q +LP + P PA
Sbjct: 559 KVLPTPQPLLPAPSGSSAPPHPA 581
Score = 36.6 bits (83), Expect = 0.19
Identities = 55/195 (28%), Positives = 68/195 (34%), Gaps = 46/195 (23%)
Query: 1227 LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADED 1286
+++S P S PP P + A PSV + S+ S S+S A
Sbjct: 241 VATSVPAPS---PPLAPVPAL-----APAPPSVPTLISDSNPLSVSASVLVPVPASAPPS 292
Query: 1287 GPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPP 1346
GP+P L A LS V L + P PP A V P
Sbjct: 293 GPVP-------------------LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPV 333
Query: 1347 PRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPA 1406
P P P P PPAAP AP P +P+ T + G P P PA
Sbjct: 334 PTPVLAPMPAS--------TPPAAP-------AP--PSVPM-PTPTPSSGPPSTPTLIPA 375
Query: 1407 GRARGGSPAPLPAKV 1421
A PAP PA +
Sbjct: 376 -FAPTPVPAPTPAPI 389
Score = 31.6 bits (70), Expect = 6.3
Identities = 18/55 (32%), Positives = 20/55 (36%)
Query: 1329 PVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP 1383
P PP PA V P P P PP T + P AP P+ T P
Sbjct: 342 PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTP 396
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 102 bits (254), Expect = 3e-21
Identities = 179/729 (24%), Positives = 232/729 (31%), Gaps = 109/729 (14%)
Query: 758 PAPQIPA------AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR-PQSV 810
P PQ P+ L G SS P Q SP + SP S S Q
Sbjct: 97 PRPQSPSDLDSLDGRSLNDDG-SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP 155
Query: 811 SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPE 870
+RP PPL P P PQ P + P Q + P S P +PP Q P
Sbjct: 156 ARPYHPPPLFP-PSPQPPDSTPR----QPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
Query: 871 GPLPPAPHLPPSST----------------SSAVASSSETSSRLPAPTPSDFQLQFPPSQ 914
G PP P L P T +S+V + P TP
Sbjct: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA 270
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
P K PT P V P PPP F VT P LP P AL N
Sbjct: 271 PPTKPPTTP-----VGGGNLPSAPPPANFPHVT---PNLPPPPALRP-----------LN 311
Query: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAE 1034
A +P G L SP A GQ G P P P AP + LPP
Sbjct: 312 NASASPPGLGAQPLPGHLPSPHA----MGQGMGGLPPGPEKGPTLAP-SPHSLPP----- 361
Query: 1035 NKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGS 1094
A+SS P P Y S S + S + S
Sbjct: 362 ---------------ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS----SASPFPAS 402
Query: 1095 VLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNK 1154
P Y +FP P Q +LPS + + + +LL + A
Sbjct: 403 QALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-RLLANSNAHPGP 461
Query: 1155 YRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAA 1214
+ +S P + + Q+++ +Q + + + P+
Sbjct: 462 FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
Query: 1215 SSEGH-----RLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269
S H P G L PG + PPPH +++ G G P + + +SSS S
Sbjct: 522 GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH--SQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 1270 SSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDP 1329
S S S + P P P + T A + AG K P
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPP 638
Query: 1330 VHQPPPPPATLKVAEPPPRPPPPPPP--TGQMNGTVDHPPPAAPERKPLGT-APHCPRLP 1386
+ P P K A PP P PP TG G PPA P GT P P +
Sbjct: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP-----GTFKPGSPTV- 692
Query: 1387 LRKTYRENVGGPG-APEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML- 1444
GPG P P+G P PA ++ I++ A E E + +
Sbjct: 693 ----------GPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742
Query: 1445 --KGPPPEP 1451
+ P P P
Sbjct: 743 PARSPSPPP 751
Score = 100 bits (250), Expect = 8e-21
Identities = 151/572 (26%), Positives = 190/572 (33%), Gaps = 134/572 (23%)
Query: 545 APIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS---AVAMLNTPDG 601
AP++ +FQ P G+ P Q P G VL G + P A + + P+G
Sbjct: 196 APMEPPTSRMFQAP----PGAPPPHPQLYPGGTGG--VLSGPPMGPKGGGAASSVGGPNG 249
Query: 602 LVQ---PATPAAATGEAAPVLTVQPAPQAP------PAVSTPLPLGLQQPQAQQPPQA-P 651
Q P TP + + A P P P+ P P PP P
Sbjct: 250 GKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309
Query: 652 TPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA 711
A+A P QP PG SP +GQ LP + P A
Sbjct: 310 LNNASASPPGLGAQPLPGHLPSPH--AMGQGMGG--------------LPPGPEKGPTLA 353
Query: 712 EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP 771
PH PAS APP + ++ + A + S ASP PA Q + P P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 772 GPSS-----------SPSLPHQAPLGDSPHLPSPH-------PTRPPSRPPSR-PQSVSR 812
P+S PSLP QA P P P+ P PPS QS +
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
Query: 813 PPSEPPLHPCPPPQAPPTLPGIFVIQNQ-----LGVPPPASNPAPTAPGPPQPPLRPQSQ 867
PP H Q Q Q G PPP + P P G
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
Query: 868 PPEG---PLPPAP-HLPPSS---------------TSSAVASSSETSSRLPAPTPSDFQL 908
P G P PP P HLPP +SS+ +SSS + P PS
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS---- 589
Query: 909 QFPPSQGPHKSPTPPPTLHLV-----------------------PEPAAPPP-----PPP 940
PSQGP +P P P + V P PPP P P
Sbjct: 590 ---PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSP 646
Query: 941 RTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQT----STSLGPLTSPA 996
++ T P P + P G + PA P T S ++GP P
Sbjct: 647 GAYKTATPPGYKPGSPPSFRT---GTPPGY----RGTSPPAGPGTFKPGSPTVGPGPLPP 699
Query: 997 ASVLVSGQAPSGTPTAPSHAPAPA---PMAAT 1025
A PSG P+ P APA P++AT
Sbjct: 700 A-------GPSGLPSLPPPPAAPASGPPLSAT 724
Score = 91.3 bits (225), Expect = 7e-18
Identities = 159/661 (24%), Positives = 221/661 (33%), Gaps = 137/661 (20%)
Query: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPK-------PAGVLPP--KLYQ- 365
P PS QP P + P P+V P++P P G PP +LY
Sbjct: 163 PLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222
Query: 366 -----LTPKPFAP-AGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419
L+ P P G + G P Q P ++ ++G +G AP
Sbjct: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG---------APPT 273
Query: 420 QANVFKQPPATTTGAA--PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477
+ PP T G P PP A H+ P LP
Sbjct: 274 K------PPTTPVGGGNLPSAPPPA------------------NFPHVTPN-----LPPP 304
Query: 478 PAVQLPQQLSALPANVGGQILAA--AAPHTGGQLIANPILTNQNLAGPLSLGPVLAP--H 533
PA++ SA P +G Q L +PH GQ + L GP LAP H
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG-------LPPGPEKGPTLAPSPH 357
Query: 534 SGAHSAHILSAAPIQV--GQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS 591
S ++ A P++ + S ++ S + + P PA A + PP+
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP-PPT 416
Query: 592 AVAMLNTPDGLVQPATPAAATGEAAPV-----------LTVQPAPQAP---------PAV 631
++++ N P QP+ P+ A P P P P P V
Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476
Query: 632 STPLPLGLQQPQAQQPPQAPTPQ-------AAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
ST QQ Q QQ Q Q + PP P P G +S P +
Sbjct: 477 STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH-----AHPYA 531
Query: 685 ATPT--AILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
+P+ ++ LP SQ S GP+ +S S+ +Q P + +
Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591
Query: 743 AGLGPQAPDSQASPAPAPQIPA------------AAPLKGPGPSSSPSLPHQAPLGDSPH 790
G Q +P P P +P A P + S P P G
Sbjct: 592 QG-------PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 791 LPSPHPTR-PPSRPPSRPQS--VSRPP----SEPPLHPCP-PPQAPPTLPGIFVIQNQLG 842
P + T PP P P S PP + PP P P +P PG G
Sbjct: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP------PEGPLPPAPHLPPSSTSSAVASSSETSS 896
+P PA A GPP + + +P PE P+PPA P V S + S+
Sbjct: 705 LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764
Query: 897 R 897
R
Sbjct: 765 R 765
Score = 75.5 bits (184), Expect = 4e-13
Identities = 98/344 (28%), Positives = 123/344 (35%), Gaps = 78/344 (22%)
Query: 626 QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
Q P P PL PQ PP +T QP PS
Sbjct: 153 QGPARPYHPPPLFPPSPQ--------------PPDSTPRQPEASFEPH---------PSV 189
Query: 686 TPT---AILTQDSLQMFLPQERSQQPLSAEGPHLSV-PASV--IVSAPPPAQDPAPATPV 739
TPT A + + +MF Q P A PH + P ++S PP A
Sbjct: 190 TPTGYHAPMEPPTSRMF------QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASS 243
Query: 740 AKGAGLGPQAP---------DSQASPAPAPQIPAAAPLKGPGPSSSP---SLPHQAPLGD 787
G G Q P S AS AP P P P+ G S+P + PH
Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGAP-PTKPPTTPVGGGNLPSAPPPANFPHV----- 297
Query: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847
+P+LP P RP + + P + P P LP + +G PP
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQP------------LPGHLPSPHAMGQGMGGLPPG 345
Query: 848 SNPAPT-APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906
PT AP P P P S P P+ SS+S+A +SSS +SS +P P+
Sbjct: 346 PEKGPTLAPSPHSLP--PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
Query: 907 QL-----QFPPSQGPHKSPTPPP-TLHLVPEPA----APPPPPP 940
L FPP S PP T +P A PPPPPP
Sbjct: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Score = 68.6 bits (166), Expect = 5e-11
Identities = 144/574 (25%), Positives = 195/574 (33%), Gaps = 106/574 (18%)
Query: 312 AASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPF 371
++S +G P +P G G+ P P P H TP + P PP L L
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN-LPP------PPALRPLNNASA 315
Query: 372 APAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATT 431
+P G L Q PG LP Q + + G P L + PPA++
Sbjct: 316 SPPG--LGAQPLPGHLPSPHAMGQGMGGLPPGPE---------KGPTLAPSPHSLPPASS 364
Query: 432 TGAAPPQP-PGALSKPMSVHLLNQGSS-----IVIPAQHMLPG-QNQFLLPGAPAV---- 480
+ APP P + S S + SS PA LP + F P + +V
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
Query: 481 ------QLPQQL----SALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVL 530
LP Q P G++LA + H G P Q+ A P PV
Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP---FPPSTGAQSTAHP----PVS 477
Query: 531 APHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPP 590
H H Q Q Q +G P + P P ++ + P
Sbjct: 478 THH---HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534
Query: 591 SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQA 650
S ++ P G PA + V Q P PP S+ +
Sbjct: 535 SLGSLRPYPPG------PAHLPPPHSQVSYSQAGPNGPPVSSS------------SNSSS 576
Query: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710
T Q + P + P PS G +P P PT + +L + S S
Sbjct: 577 STSQGSYP--CSHPSPSQGPQGAP------YPFPPVPTVTTSSATLSTVIATVAS----S 624
Query: 711 AEGPHLSVPASVIVSAPPPAQDPAPATPVAKGA---GLGPQAPDSQASPAPAPQIPAAAP 767
G + P PPP AP+ K A G P +P S + P P +P
Sbjct: 625 PAGYKTASP-----PGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP-PGYRGTSP 678
Query: 768 LKGPG------PSSSPS-LPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS---EP 817
GPG P+ P LP P G P LP P P P S PP + + P+ E
Sbjct: 679 PAGPGTFKPGSPTVGPGPLPPAGPSG-LPSLPPP-PAAPASGPPLSATQIKQEPAEEYET 736
Query: 818 PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
P P PP ++P P + + VP AS A
Sbjct: 737 PESPVPPARSPSPPPKV------VDVPSHASQSA 764
Score = 48.9 bits (115), Expect = 4e-05
Identities = 96/433 (22%), Positives = 132/433 (30%), Gaps = 136/433 (31%)
Query: 1228 SSSAPGASTQP-PPHLPTKLVIRHGGAGGSP-------------SVTWARAS-------- 1265
S+S PG QP P HLP+ + G G P S+ A +S
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF 373
Query: 1266 --SSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVH 1323
SS SSSS+++S++SS + P P+ P + L + + +
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTG-------------------------- 1357
+ A+ PPPPP +A P P PP TG
Sbjct: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 1358 --------QMNGTVDHPPPAA-PERKPLGTAPHC---PRLPLRKTYRENVGGPG------ 1399
Q +G PPP A P G++ H P + R GP
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH 553
Query: 1400 --------APEGTPAGRARG----------------------GSPAPLPAKVDEATSG-- 1427
P G P + G+P P P TS
Sbjct: 554 SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT 613
Query: 1428 ---LIRELAAVEDELYQRMLKGPPPEPAASAAQG---TGDPDWEAPGLPPAKRR------ 1475
+I +A+ GPPP + + G T P PG PP+ R
Sbjct: 614 LSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGY 673
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
+ SP +F SP P P P A +G P+ P
Sbjct: 674 RGTSPPAGPGTFKPGSPTVG-----------------------PGP-LPPAGPSGLPSLP 709
Query: 1536 PPLHRPEAYPPSS 1548
PP P + PP S
Sbjct: 710 PPPAAPASGPPLS 722
Score = 47.8 bits (112), Expect = 8e-05
Identities = 71/287 (24%), Positives = 95/287 (33%), Gaps = 45/287 (15%)
Query: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALD 1328
S + SS +D D PS P ++ S GL G ++ H L
Sbjct: 112 SLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS------QGPARPYHPPPLF 165
Query: 1329 PVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLR 1388
P P PP +T + E P P PTG PP + + P G P P+L
Sbjct: 166 PP-SPQPPDSTPRQPEASFEPHPSVTPTGYHAPM--EPPTSRMFQAPPGAPPPHPQLYPG 222
Query: 1389 KTYRENVGGPGAPEGTPA----GRARGGSPAPLPAK-VDEATSGLIRELAAVEDELYQRM 1443
T G P P+G A G GG P P + ++SG
Sbjct: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA--------------- 267
Query: 1444 LKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQS 1503
G PP + G G+ P PP +P++ P + S
Sbjct: 268 -SGAPPTKPPTTPVGGGN----LPSAPPPANFPHVTPNLP--------PPPALRPLNNAS 314
Query: 1504 AIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550
A L Q PG P+P HA G PP + PS H+
Sbjct: 315 ASPPGLGAQPLPGHLPSP---HAMGQGMGGLPPGPEKGPTLAPSPHS 358
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/246 (26%), Positives = 82/246 (33%), Gaps = 45/246 (18%)
Query: 1331 HQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE--------RKPLGTAPHC 1382
H P PP + PP PPP P G V PP P+ P G H
Sbjct: 195 HAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
Query: 1383 PRLPLRKTYRENVGGPGAPEGTPAGRARGGS---PAPLPAKVDEATSGL--------IRE 1431
P P + G GAP P GG AP PA T L +
Sbjct: 255 P--PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312
Query: 1432 LAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR---KSESP-DVDQASF 1487
+A L + L G P P A QG G GLPP + + SP + AS
Sbjct: 313 ASASPPGLGAQPLPGHLPSPHA-MGQGMG-------GLPPGPEKGPTLAPSPHSLPPASS 364
Query: 1488 SSDSP--------QDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPAS----P 1535
S+ +P + S+ S + P PSYPH+ T S P
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
Query: 1536 PPLHRP 1541
P +P
Sbjct: 425 PKYTQP 430
Score = 45.8 bits (107), Expect = 3e-04
Identities = 89/360 (24%), Positives = 123/360 (34%), Gaps = 75/360 (20%)
Query: 1219 HRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAA 1278
H LP P SSSAP PP P S S + A ASSS SSSSSS+A
Sbjct: 357 HSLP---PASSSAPA----PPMRFPYS----------SSSSSSAAASSS---SSSSSSSA 396
Query: 1279 SSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPA 1338
S A + P + PP + ++ K Q + S+ V + PPPPP
Sbjct: 397 SPFPASQALPSYPHSFPPPTSLSVSNQ---PPKYTQPSLPSQAVWSQG------PPPPPP 447
Query: 1339 TLK-VAEPPPRPPPPPPPTGQMNGTVDHPPPAA----PERKPLGTAPHCPRLPLRKTYRE 1393
+ +A P P PP TG + HPP + +++ + ++ +
Sbjct: 448 YGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHG 505
Query: 1394 NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA 1453
N G P P G GGS + G +R L PPP
Sbjct: 506 NSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL-------PPPHSQV 556
Query: 1454 SAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD------------------ 1495
S +Q P PP + S Q S+ P
Sbjct: 557 SYSQA-------GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609
Query: 1496 ---TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGT-PASPPPLHRPEAYPPSSHNG 1551
TL+ + + S + A P P A S G + PP ++P + PPS G
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS-PPSFRTG 668
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 102 bits (254), Expect = 3e-21
Identities = 179/729 (24%), Positives = 232/729 (31%), Gaps = 109/729 (14%)
Query: 758 PAPQIPA------AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR-PQSV 810
P PQ P+ L G SS P Q SP + SP S S Q
Sbjct: 97 PRPQSPSDLDSLDGRSLNDDG-SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP 155
Query: 811 SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPE 870
+RP PPL P P PQ P + P Q + P S P +PP Q P
Sbjct: 156 ARPYHPPPLFP-PSPQPPDSTPR----QPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
Query: 871 GPLPPAPHLPPSST----------------SSAVASSSETSSRLPAPTPSDFQLQFPPSQ 914
G PP P L P T +S+V + P TP
Sbjct: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA 270
Query: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
P K PT P V P PPP F VT P LP P AL N
Sbjct: 271 PPTKPPTTP-----VGGGNLPSAPPPANFPHVT---PNLPPPPALRP-----------LN 311
Query: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAE 1034
A +P G L SP A GQ G P P P AP + LPP
Sbjct: 312 NASASPPGLGAQPLPGHLPSPHA----MGQGMGGLPPGPEKGPTLAP-SPHSLPP----- 361
Query: 1035 NKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGS 1094
A+SS P P Y S S + S + S
Sbjct: 362 ---------------ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS----SASPFPAS 402
Query: 1095 VLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNK 1154
P Y +FP P Q +LPS + + + +LL + A
Sbjct: 403 QALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-RLLANSNAHPGP 461
Query: 1155 YRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAA 1214
+ +S P + + Q+++ +Q + + + P+
Sbjct: 462 FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
Query: 1215 SSEGH-----RLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269
S H P G L PG + PPPH +++ G G P + + +SSS S
Sbjct: 522 GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH--SQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 1270 SSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDP 1329
S S S + P P P + T A + AG K P
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPP 638
Query: 1330 VHQPPPPPATLKVAEPPPRPPPPPPP--TGQMNGTVDHPPPAAPERKPLGT-APHCPRLP 1386
+ P P K A PP P PP TG G PPA P GT P P +
Sbjct: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP-----GTFKPGSPTV- 692
Query: 1387 LRKTYRENVGGPG-APEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML- 1444
GPG P P+G P PA ++ I++ A E E + +
Sbjct: 693 ----------GPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742
Query: 1445 --KGPPPEP 1451
+ P P P
Sbjct: 743 PARSPSPPP 751
Score = 100 bits (250), Expect = 8e-21
Identities = 151/572 (26%), Positives = 190/572 (33%), Gaps = 134/572 (23%)
Query: 545 APIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS---AVAMLNTPDG 601
AP++ +FQ P G+ P Q P G VL G + P A + + P+G
Sbjct: 196 APMEPPTSRMFQAP----PGAPPPHPQLYPGGTGG--VLSGPPMGPKGGGAASSVGGPNG 249
Query: 602 LVQ---PATPAAATGEAAPVLTVQPAPQAP------PAVSTPLPLGLQQPQAQQPPQA-P 651
Q P TP + + A P P P+ P P PP P
Sbjct: 250 GKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309
Query: 652 TPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA 711
A+A P QP PG SP +GQ LP + P A
Sbjct: 310 LNNASASPPGLGAQPLPGHLPSPH--AMGQGMGG--------------LPPGPEKGPTLA 353
Query: 712 EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP 771
PH PAS APP + ++ + A + S ASP PA Q + P P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 772 GPSS-----------SPSLPHQAPLGDSPHLPSPH-------PTRPPSRPPSR-PQSVSR 812
P+S PSLP QA P P P+ P PPS QS +
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
Query: 813 PPSEPPLHPCPPPQAPPTLPGIFVIQNQ-----LGVPPPASNPAPTAPGPPQPPLRPQSQ 867
PP H Q Q Q G PPP + P P G
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
Query: 868 PPEG---PLPPAP-HLPPSS---------------TSSAVASSSETSSRLPAPTPSDFQL 908
P G P PP P HLPP +SS+ +SSS + P PS
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS---- 589
Query: 909 QFPPSQGPHKSPTPPPTLHLV-----------------------PEPAAPPP-----PPP 940
PSQGP +P P P + V P PPP P P
Sbjct: 590 ---PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSP 646
Query: 941 RTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQT----STSLGPLTSPA 996
++ T P P + P G + PA P T S ++GP P
Sbjct: 647 GAYKTATPPGYKPGSPPSFRT---GTPPGY----RGTSPPAGPGTFKPGSPTVGPGPLPP 699
Query: 997 ASVLVSGQAPSGTPTAPSHAPAPA---PMAAT 1025
A PSG P+ P APA P++AT
Sbjct: 700 A-------GPSGLPSLPPPPAAPASGPPLSAT 724
Score = 91.3 bits (225), Expect = 7e-18
Identities = 159/661 (24%), Positives = 221/661 (33%), Gaps = 137/661 (20%)
Query: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPK-------PAGVLPP--KLYQ- 365
P PS QP P + P P+V P++P P G PP +LY
Sbjct: 163 PLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222
Query: 366 -----LTPKPFAP-AGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419
L+ P P G + G P Q P ++ ++G +G AP
Sbjct: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG---------APPT 273
Query: 420 QANVFKQPPATTTGAA--PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477
+ PP T G P PP A H+ P LP
Sbjct: 274 K------PPTTPVGGGNLPSAPPPA------------------NFPHVTPN-----LPPP 304
Query: 478 PAVQLPQQLSALPANVGGQILAA--AAPHTGGQLIANPILTNQNLAGPLSLGPVLAP--H 533
PA++ SA P +G Q L +PH GQ + L GP LAP H
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG-------LPPGPEKGPTLAPSPH 357
Query: 534 SGAHSAHILSAAPIQV--GQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS 591
S ++ A P++ + S ++ S + + P PA A + PP+
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP-PPT 416
Query: 592 AVAMLNTPDGLVQPATPAAATGEAAPV-----------LTVQPAPQAP---------PAV 631
++++ N P QP+ P+ A P P P P P V
Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476
Query: 632 STPLPLGLQQPQAQQPPQAPTPQ-------AAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
ST QQ Q QQ Q Q + PP P P G +S P +
Sbjct: 477 STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH-----AHPYA 531
Query: 685 ATPT--AILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
+P+ ++ LP SQ S GP+ +S S+ +Q P + +
Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591
Query: 743 AGLGPQAPDSQASPAPAPQIPA------------AAPLKGPGPSSSPSLPHQAPLGDSPH 790
G Q +P P P +P A P + S P P G
Sbjct: 592 QG-------PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 791 LPSPHPTR-PPSRPPSRPQS--VSRPP----SEPPLHPCP-PPQAPPTLPGIFVIQNQLG 842
P + T PP P P S PP + PP P P +P PG G
Sbjct: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
Query: 843 VPPPASNPAPTAPGPPQPPLRPQSQP------PEGPLPPAPHLPPSSTSSAVASSSETSS 896
+P PA A GPP + + +P PE P+PPA P V S + S+
Sbjct: 705 LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764
Query: 897 R 897
R
Sbjct: 765 R 765
Score = 75.5 bits (184), Expect = 4e-13
Identities = 98/344 (28%), Positives = 123/344 (35%), Gaps = 78/344 (22%)
Query: 626 QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
Q P P PL PQ PP +T QP PS
Sbjct: 153 QGPARPYHPPPLFPPSPQ--------------PPDSTPRQPEASFEPH---------PSV 189
Query: 686 TPT---AILTQDSLQMFLPQERSQQPLSAEGPHLSV-PASV--IVSAPPPAQDPAPATPV 739
TPT A + + +MF Q P A PH + P ++S PP A
Sbjct: 190 TPTGYHAPMEPPTSRMF------QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASS 243
Query: 740 AKGAGLGPQAP---------DSQASPAPAPQIPAAAPLKGPGPSSSP---SLPHQAPLGD 787
G G Q P S AS AP P P P+ G S+P + PH
Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGAP-PTKPPTTPVGGGNLPSAPPPANFPHV----- 297
Query: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847
+P+LP P RP + + P + P P LP + +G PP
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQP------------LPGHLPSPHAMGQGMGGLPPG 345
Query: 848 SNPAPT-APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906
PT AP P P P S P P+ SS+S+A +SSS +SS +P P+
Sbjct: 346 PEKGPTLAPSPHSLP--PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
Query: 907 QL-----QFPPSQGPHKSPTPPP-TLHLVPEPA----APPPPPP 940
L FPP S PP T +P A PPPPPP
Sbjct: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Score = 68.6 bits (166), Expect = 5e-11
Identities = 144/574 (25%), Positives = 195/574 (33%), Gaps = 106/574 (18%)
Query: 312 AASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPF 371
++S +G P +P G G+ P P P H TP + P PP L L
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN-LPP------PPALRPLNNASA 315
Query: 372 APAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATT 431
+P G L Q PG LP Q + + G P L + PPA++
Sbjct: 316 SPPG--LGAQPLPGHLPSPHAMGQGMGGLPPGPE---------KGPTLAPSPHSLPPASS 364
Query: 432 TGAAPPQP-PGALSKPMSVHLLNQGSS-----IVIPAQHMLPG-QNQFLLPGAPAV---- 480
+ APP P + S S + SS PA LP + F P + +V
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
Query: 481 ------QLPQQL----SALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVL 530
LP Q P G++LA + H G P Q+ A P PV
Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP---FPPSTGAQSTAHP----PVS 477
Query: 531 APHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPP 590
H H Q Q Q +G P + P P ++ + P
Sbjct: 478 THH---HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534
Query: 591 SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQA 650
S ++ P G PA + V Q P PP S+ +
Sbjct: 535 SLGSLRPYPPG------PAHLPPPHSQVSYSQAGPNGPPVSSS------------SNSSS 576
Query: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710
T Q + P + P PS G +P P PT + +L + S S
Sbjct: 577 STSQGSYP--CSHPSPSQGPQGAP------YPFPPVPTVTTSSATLSTVIATVAS----S 624
Query: 711 AEGPHLSVPASVIVSAPPPAQDPAPATPVAKGA---GLGPQAPDSQASPAPAPQIPAAAP 767
G + P PPP AP+ K A G P +P S + P P +P
Sbjct: 625 PAGYKTASP-----PGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP-PGYRGTSP 678
Query: 768 LKGPG------PSSSPS-LPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS---EP 817
GPG P+ P LP P G P LP P P P S PP + + P+ E
Sbjct: 679 PAGPGTFKPGSPTVGPGPLPPAGPSG-LPSLPPP-PAAPASGPPLSATQIKQEPAEEYET 736
Query: 818 PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
P P PP ++P P + + VP AS A
Sbjct: 737 PESPVPPARSPSPPPKV------VDVPSHASQSA 764
Score = 48.9 bits (115), Expect = 4e-05
Identities = 96/433 (22%), Positives = 132/433 (30%), Gaps = 136/433 (31%)
Query: 1228 SSSAPGASTQP-PPHLPTKLVIRHGGAGGSP-------------SVTWARAS-------- 1265
S+S PG QP P HLP+ + G G P S+ A +S
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF 373
Query: 1266 --SSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVH 1323
SS SSSS+++S++SS + P P+ P + L + + +
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
Query: 1324 NTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTG-------------------------- 1357
+ A+ PPPPP +A P P PP TG
Sbjct: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 1358 --------QMNGTVDHPPPAA-PERKPLGTAPHC---PRLPLRKTYRENVGGPG------ 1399
Q +G PPP A P G++ H P + R GP
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH 553
Query: 1400 --------APEGTPAGRARG----------------------GSPAPLPAKVDEATSG-- 1427
P G P + G+P P P TS
Sbjct: 554 SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT 613
Query: 1428 ---LIRELAAVEDELYQRMLKGPPPEPAASAAQG---TGDPDWEAPGLPPAKRR------ 1475
+I +A+ GPPP + + G T P PG PP+ R
Sbjct: 614 LSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGY 673
Query: 1476 KSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
+ SP +F SP P P P A +G P+ P
Sbjct: 674 RGTSPPAGPGTFKPGSPTVG-----------------------PGP-LPPAGPSGLPSLP 709
Query: 1536 PPLHRPEAYPPSS 1548
PP P + PP S
Sbjct: 710 PPPAAPASGPPLS 722
Score = 47.8 bits (112), Expect = 8e-05
Identities = 71/287 (24%), Positives = 95/287 (33%), Gaps = 45/287 (15%)
Query: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALD 1328
S + SS +D D PS P ++ S GL G ++ H L
Sbjct: 112 SLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS------QGPARPYHPPPLF 165
Query: 1329 PVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLR 1388
P P PP +T + E P P PTG PP + + P G P P+L
Sbjct: 166 PP-SPQPPDSTPRQPEASFEPHPSVTPTGYHAPM--EPPTSRMFQAPPGAPPPHPQLYPG 222
Query: 1389 KTYRENVGGPGAPEGTPA----GRARGGSPAPLPAK-VDEATSGLIRELAAVEDELYQRM 1443
T G P P+G A G GG P P + ++SG
Sbjct: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA--------------- 267
Query: 1444 LKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQS 1503
G PP + G G+ P PP +P++ P + S
Sbjct: 268 -SGAPPTKPPTTPVGGGN----LPSAPPPANFPHVTPNLP--------PPPALRPLNNAS 314
Query: 1504 AIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550
A L Q PG P+P HA G PP + PS H+
Sbjct: 315 ASPPGLGAQPLPGHLPSP---HAMGQGMGGLPPGPEKGPTLAPSPHS 358
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/246 (26%), Positives = 82/246 (33%), Gaps = 45/246 (18%)
Query: 1331 HQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE--------RKPLGTAPHC 1382
H P PP + PP PPP P G V PP P+ P G H
Sbjct: 195 HAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
Query: 1383 PRLPLRKTYRENVGGPGAPEGTPAGRARGGS---PAPLPAKVDEATSGL--------IRE 1431
P P + G GAP P GG AP PA T L +
Sbjct: 255 P--PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312
Query: 1432 LAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR---KSESP-DVDQASF 1487
+A L + L G P P A QG G GLPP + + SP + AS
Sbjct: 313 ASASPPGLGAQPLPGHLPSPHA-MGQGMG-------GLPPGPEKGPTLAPSPHSLPPASS 364
Query: 1488 SSDSP--------QDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPAS----P 1535
S+ +P + S+ S + P PSYPH+ T S P
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
Query: 1536 PPLHRP 1541
P +P
Sbjct: 425 PKYTQP 430
Score = 45.8 bits (107), Expect = 3e-04
Identities = 89/360 (24%), Positives = 123/360 (34%), Gaps = 75/360 (20%)
Query: 1219 HRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAA 1278
H LP P SSSAP PP P S S + A ASSS SSSSSS+A
Sbjct: 357 HSLP---PASSSAPA----PPMRFPYS----------SSSSSSAAASSS---SSSSSSSA 396
Query: 1279 SSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPA 1338
S A + P + PP + ++ K Q + S+ V + PPPPP
Sbjct: 397 SPFPASQALPSYPHSFPPPTSLSVSNQ---PPKYTQPSLPSQAVWSQG------PPPPPP 447
Query: 1339 TLK-VAEPPPRPPPPPPPTGQMNGTVDHPPPAA----PERKPLGTAPHCPRLPLRKTYRE 1393
+ +A P P PP TG + HPP + +++ + ++ +
Sbjct: 448 YGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHG 505
Query: 1394 NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA 1453
N G P P G GGS + G +R L PPP
Sbjct: 506 NSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL-------PPPHSQV 556
Query: 1454 SAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD------------------ 1495
S +Q P PP + S Q S+ P
Sbjct: 557 SYSQA-------GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609
Query: 1496 ---TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGT-PASPPPLHRPEAYPPSSHNG 1551
TL+ + + S + A P P A S G + PP ++P + PPS G
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS-PPSFRTG 668
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 100 bits (249), Expect = 1e-20
Identities = 137/564 (24%), Positives = 201/564 (35%), Gaps = 66/564 (11%)
Query: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAH 537
P +Q P + +A+P A +P G + A P + L V PH
Sbjct: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAAL----VPFPHEDIL 884
Query: 538 SAHILS-----------AAPIQVGQPAL-FQMPVSLAA-GSLPTQSQPAPAGPAATT--- 581
A I+S +AP + PA+ +P AA ++ + + APA AA T
Sbjct: 885 VASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEG 944
Query: 582 --VLQGVTLPPSAVAML-------NTPDGLVQPATPAAATGE--AAPVLTVQPAPQAPPA 630
+ G + +A+A+ TP+G V PAT A E A V P A PA
Sbjct: 945 MSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPA 1004
Query: 631 VSTPLPLGLQQPQAQQP-PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTA 689
+ P P P A P P+ PT AAA P P +PE+ P +A PT
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT--SPAAAVPT- 1061
Query: 690 ILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA 749
P+E + + P + V P PA A P P+
Sbjct: 1062 -----------PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT-------PEE 1103
Query: 750 PDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQS 809
P S A+ P P+ PA+ P P S P + P P+P P+ S +
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP---AVPTPEESASAA 1160
Query: 810 VSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP--PPASNPAPTAPGPPQPPLRPQSQ 867
V+ P E P P + L P P AS P P A +
Sbjct: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA----MVATLEEFT 1216
Query: 868 PPEGPLPPAPHLPPSSTSSAVASSSE-TSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL 926
P +P + P+S ++AV++ E TS PT + P + +P ++
Sbjct: 1217 SPAASVPTSEE--PASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASV 1274
Query: 927 HLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986
EPA+P + +P A+P P+ VP+ + A P + S
Sbjct: 1275 PTPEEPASPAAAVSN-LEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVS 1333
Query: 987 TSLGPLTSPAASVLVSGQAPSGTP 1010
P +A + GTP
Sbjct: 1334 PIGVPFLGVSAHTDSVPISEEGTP 1357
Score = 97.8 bits (242), Expect = 7e-20
Identities = 120/477 (25%), Positives = 178/477 (37%), Gaps = 36/477 (7%)
Query: 591 SAVAMLNTPDGLVQPATPAAATGE---AAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP 647
+++A + P+G A E A +++++ AVS P + P
Sbjct: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
Query: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707
A + P+ T P + + V G P AI + + P+
Sbjct: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
Query: 708 PLSAEGPHLSVPASVIVSAP-----PPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQ 761
+ P A+V VS P P A P P P + A + P+ P S A+ P P+
Sbjct: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037
Query: 762 IPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP--PL 819
P + P P S P + P SP P P+ P + P EP P
Sbjct: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
Query: 820 HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
P P+ PT P V + P A+ P P P P + P + P P P P
Sbjct: 1096 AAVPTPE-EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV-PTPEEPAFPAPAVP-T 1152
Query: 880 PPSSTSSAVASSSETSSRLPA---PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPP 936
P S S+AVA + S PA PTP++ F + PT P VP PAA
Sbjct: 1153 PEESASAAVAVPTPEESASPAAAVPTPAE-SASFAAVVATLEEPTSPAA--SVPTPAA-- 1207
Query: 937 PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLG------ 990
T + T+P ++P + V + + A P + ++S
Sbjct: 1208 --MVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE 1265
Query: 991 PLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNV 1047
L+SPAASV + + P+ A S+ PA AA P + A A+++PT V
Sbjct: 1266 ELSSPAASV-PTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA---IPAASVPTPEV 1318
Score = 83.6 bits (205), Expect = 1e-15
Identities = 148/589 (25%), Positives = 216/589 (36%), Gaps = 94/589 (15%)
Query: 352 QPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA--GQNV 409
Q AG P L + P P+ T + AL +P+ T +AA A G V
Sbjct: 813 QVTKAGNTEPVLEEWIPVLQRPS-RTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Query: 410 VLSGFPAP---ALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHML 466
V + P P L A++ T AA P A ++V + +G++ V
Sbjct: 872 VAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSV-PEGTAAVAAVSS-- 928
Query: 467 PGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLA-GPLS 525
P + APAV +A G +A +P I PI GP++
Sbjct: 929 PEET------APAV------AAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVT 976
Query: 526 LGPVLAPHSGAHSAHILSAAPIQVGQPALF----QMPVSLAAGSLPTQSQPA-------- 573
+ +A + + P + PA + P S AA ++PT +P
Sbjct: 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPP 1035
Query: 574 ---PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP-- 628
P PAA P S A + TP+ +P +PAAA P P+ P
Sbjct: 1036 PEEPTSPAAAVPTPEE--PTSPAAAVPTPE---EPTSPAAAV----------PTPEEPTS 1080
Query: 629 PAVSTPLPLGLQQPQAQQP-PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP 687
PA + P P P A P P+ PT AAA P T +P+ A+ P P +A P
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--TPEEPASPAAAVPTPEEPASPAAAVP 1138
Query: 688 TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGLG 746
T P+E + + P S A+V V P + PA A P A+ A
Sbjct: 1139 T------------PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
Query: 747 P-----QAPDSQASPAPAPQIPAAAPLKGPGPSSS-PSLPHQAPLGDSPHLPSPHPTRPP 800
+ P S A+ P P A + P++S P+ A L + P PT P
Sbjct: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE-EPTSPA 1245
Query: 801 SRPPS------------RPQSVSRPPSEPPL--HPCPPPQAPPTLPGIFVIQNQLGVPPP 846
+ P+ P+ +S P + P P P A L + P
Sbjct: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV 1305
Query: 847 ASNPAPTAPGPPQPPLRPQSQPPEGPLPP--APHLPPSSTSSAVASSSE 893
A+ PA + P P P + + PP + P P L S+ + +V S E
Sbjct: 1306 AAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEE 1354
Score = 71.6 bits (174), Expect = 5e-12
Identities = 82/343 (23%), Positives = 123/343 (35%), Gaps = 43/343 (12%)
Query: 563 AGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPA----TPAAATGEAAPV 618
A ++PT +P A T + P S A + TP+ PA TP T AA V
Sbjct: 1056 AAAVPTPEEPTSPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
Query: 619 LTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS---PE 675
T P A PA + P P + A PTP+ A P P P +++ P
Sbjct: 1112 PT--PEEPASPAAAVPTP----EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT 1165
Query: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP 735
P +A PT + + E P ++ ++ A++ P A P
Sbjct: 1166 PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS 1225
Query: 736 ATPVAKGAGL-GPQAPDSQASPAPAPQIP--AAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
P + A + P+ P S A+ P + P +AA + P SSP + +P
Sbjct: 1226 EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP----------AASVP 1275
Query: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAP 852
+P P+ P + ++ P S P P A P VP P P
Sbjct: 1276 TP---EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA----------ASVPTPEVPAIP 1322
Query: 853 TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS 895
A PP + P P G +P S + V + ++
Sbjct: 1323 AAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
Score = 68.9 bits (167), Expect = 4e-11
Identities = 103/430 (23%), Positives = 158/430 (36%), Gaps = 52/430 (12%)
Query: 675 EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPA 734
E I + Q PS T +D+L LP ++A P A V P P +D
Sbjct: 826 EWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAV-PAPEGTAVVAALVPFPHEDIL 884
Query: 735 PATPVAKG----AGLGPQAPDSQASPAPAPQIP----AAAPLKGP---GPSSSPSLPHQ- 782
A+ V+ AP+ PA +P A A + P P+ + ++ +
Sbjct: 885 VASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEG 944
Query: 783 --APLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ 840
A G SP + T P + P E P+ P AP V +
Sbjct: 945 MSAVAGFSPEWAALAITVPITEEDGTP--------EGPVTPATTVHAPEEPDTAAV---R 993
Query: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQP-PEGPLPPAPHLPP----SSTSSAVASSSE-T 894
+ P ++PA P P +P + P PE P PA +PP +S ++AV + E T
Sbjct: 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
Query: 895 SSRLPAPTPSDFQLQFPPSQGPHKSPTPP-PTLHLVPEPAAPPPPPPRTFQMVTTPFPAL 953
S PTP + P+ PTP PT P A P P P T+P A+
Sbjct: 1054 SPAAAVPTPEE------PTSPAAAVPTPEEPTS---PAAAVPTPEEP------TSPAAAV 1098
Query: 954 PQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAP 1013
P P+ VP+ + A P + ++ + +P + P+ +A
Sbjct: 1099 PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS 1158
Query: 1014 SHAPAPAP--MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
+ P P A+ PAE+ +FA+ + TL + S P+ + L
Sbjct: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLE--EPTSPAASVPTPAAMVATLEEFT 1216
Query: 1072 KPPTLQPSKE 1081
P P+ E
Sbjct: 1217 SPAASVPTSE 1226
Score = 48.9 bits (115), Expect = 4e-05
Identities = 113/493 (22%), Positives = 164/493 (33%), Gaps = 62/493 (12%)
Query: 149 AAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQD--------VVNKALSVQPFLQP 200
AAAV+A +A P T + P A+ P++ + + +S P
Sbjct: 898 AAAVSAPERATVPAVT----VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953
Query: 201 VGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVS 260
PI G P G AT P V P S A P
Sbjct: 954 EWAALAITVPITEEDGTPEGPVTPATTVHAPEEP-DTAAVRVSTPEEPASPAAAVPTPEE 1012
Query: 261 GYLASAAGPS--EPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTG 318
+AA P+ EP + A+A P+ + +AAV T S PT
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEP-----TSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
Query: 319 TPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTP-KPFAPAGAT 377
+ P P +SP P +P P P P TP +P +PA A
Sbjct: 1068 PAAAVPTPEEP---TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
Query: 378 LTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAP- 436
T + EP + P+ F A P P A+ P A+P
Sbjct: 1125 PTPE-EPASPAAAVPTPEEPAFPA----------PAVPTPEESASAAVAVPTPEESASPA 1173
Query: 437 ---PQPPGALSKPMSVHLLNQ----GSSIVIPAQHMLPGQNQFLLPGA--PAVQLPQQLS 487
P P + S V L + +S+ PA M+ +F P A P + P L+
Sbjct: 1174 AAVPTPAESASFAAVVATLEEPTSPAASVPTPAA-MVATLEEFTSPAASVPTSEEPASLA 1232
Query: 488 ALPANVGGQILAAAAPHTGGQ--LIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAA 545
A +N AAA T + A +LT + L+ P + P P A A +S
Sbjct: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP--TPEEPASPAAAVSNL 1290
Query: 546 PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQP 605
A P ++P S P P PA +P +AV + + P
Sbjct: 1291 EEPASPAAAVPTP---EVAAIPAASVPTPEVPA---------IPAAAVPPMEEVSPIGVP 1338
Query: 606 ATPAAATGEAAPV 618
+A ++ P+
Sbjct: 1339 FLGVSAHTDSVPI 1351
Score = 38.9 bits (89), Expect = 0.039
Identities = 83/370 (22%), Positives = 127/370 (34%), Gaps = 60/370 (16%)
Query: 1198 PDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSP 1257
P+E S + ++ P +S +P P ++P A+ PPP PT SP
Sbjct: 997 PEEPASPAAAVPTPEEPTSPAAAVPT--PEEPTSPAAAV-PPPEEPT-----------SP 1042
Query: 1258 SVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAG 1317
+ +++ + +S A+++ E+ P+ P T E + + +E
Sbjct: 1043 A-------AAVPTPEEPTSPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEP- 1091
Query: 1318 LSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLG 1377
P P P A P P P P + + PAA P
Sbjct: 1092 ---------TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
Query: 1378 TAPHCPRLPLRKTYR---------ENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGL 1428
A P +P + E P A TPA A S A + A ++E TS
Sbjct: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA---SFAAVVATLEEPTSPA 1199
Query: 1429 I-----RELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVD 1483
+ A +E P E AS A +P E P P A E P
Sbjct: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP--EEPTSPAAAVPTLEEPTSS 1257
Query: 1484 QASFSS----DSPQDDTLT-EHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPL 1538
A+ + SP T E S ++ NL++ +PA + P A PA+ P
Sbjct: 1258 AAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP--ASPAAAVPTPEVAAIPAASVPT 1315
Query: 1539 HRPEAYPPSS 1548
A P ++
Sbjct: 1316 PEVPAIPAAA 1325
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 100 bits (249), Expect = 1e-20
Identities = 111/375 (29%), Positives = 130/375 (34%), Gaps = 75/375 (20%)
Query: 625 PQAPPAV----STPLPLGLQQPQAQQPP----QAPTPQAAAPPQATTPQPSP-GLASSPE 675
PQ PP+ P P G QPQ PP Q P PQ PQ P P G +
Sbjct: 47 PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106
Query: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH-------LSVPASVIVSAPP 728
K + P P Q Q PQ P +GP P PP
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQ---PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 163
Query: 729 PAQDP---APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG------PGPSSSPSL 779
P D + +P K G PQ + P P P P P +G P P P
Sbjct: 164 PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 223
Query: 780 PHQAPLGD----SPHLPSPHPTRPPSRPPSRPQSVSRPPSEP----------PLHPCPP- 824
P P GD S P P PP + ++PQ PP +P P P PP
Sbjct: 224 P--PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281
Query: 825 -PQAPPTLPGIFVIQNQLGV-----PPPASNPAPTAPGPPQPPLRPQSQPPEG------- 871
PQ PP G ++ PPP P GPP PP +PQ PP+G
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGGNKPQGP 339
Query: 872 PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPE 931
P P P PP S S+R P P Q PP Q + PPP P+
Sbjct: 340 PPPGKPQGPPPQ-----GGSKSRSARSPPGKP-----QGPPQQEGNNPQGPPPPAGGNPQ 389
Query: 932 -----PAAPPPPPPR 941
PA P PPR
Sbjct: 390 QPQAPPAGQPQGPPR 404
Score = 97.4 bits (241), Expect = 9e-20
Identities = 99/363 (27%), Positives = 121/363 (33%), Gaps = 61/363 (16%)
Query: 726 APPPA--QDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG-------PGPSSS 776
APP + P +P K G PQ + P P P P P +G P P
Sbjct: 39 APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98
Query: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP----------PLHPCPP-- 824
P Q SP P P PP + ++PQ PP +P P P PP
Sbjct: 99 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158
Query: 825 PQAPPTLPGIFVIQNQLGVPPPASNPAPTA----PGPPQPPLRPQSQPPEGPLPPAPHLP 880
PQ PP G ++ P P P GPP PP +PQ PP+G P P
Sbjct: 159 PQGPPP-QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 881 PSSTSS--AVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
P + S+R P P Q PP QG ++ PP P P P P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKP-----QGPPPQGGNQPQGPP------PPPGKPQGP 266
Query: 939 PPRTFQMVT-TPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAA 997
PP+ P P PQ P G + P PQ G
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPP--------PQGGSKSRSSRSPPGKPQGPPPQG------- 311
Query: 998 SVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGK 1057
G P G P P P P P P K + +++A S PGK
Sbjct: 312 -----GNQPQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK 365
Query: 1058 PSG 1060
P G
Sbjct: 366 PQG 368
Score = 86.3 bits (212), Expect = 2e-16
Identities = 80/310 (25%), Positives = 111/310 (35%), Gaps = 40/310 (12%)
Query: 774 SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSE---PPLHPCPPPQAPPT 830
SS+ +L +SP L + +P P + ++PQ PP + PP PQ PP
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73
Query: 831 LPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVAS 890
PG G PP N P P PP +PQ PP+G +P PP
Sbjct: 74 PPG-----KPQGPPPQGGN----KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ---GP 121
Query: 891 SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP------------- 937
+ ++ P P + Q PP QG +K PPP +P PPP
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP----GKPQGPPPQGDNKSRSSRSPP 177
Query: 938 -----PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAP--AAPQTSTSLG 990
PPP+ P P +P+ + P G K G P ++ ++
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Query: 991 PLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
P P G P G P P P P P P K + +++
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 1051 ASSGPGKPSG 1060
+ S PGKP G
Sbjct: 297 SRSPPGKPQG 306
Score = 78.6 bits (192), Expect = 4e-14
Identities = 88/332 (26%), Positives = 99/332 (29%), Gaps = 56/332 (16%)
Query: 564 GSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQP 623
G+ P P P P PP N P G P P +
Sbjct: 126 GNQPQGPPPPPGKPQGP--------PPQGG---NKPQGPPPPGKPQGPPPQGDNKSRSSR 174
Query: 624 APQAPPAVSTPLPLGLQQPQAQQPP----QAPTPQAAAPPQATTPQPSPGLASSPEKIVL 679
+P P P P G QPQ PP Q P PQ PQ P
Sbjct: 175 SPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-------------- 218
Query: 680 GQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPP--AQDPAPAT 737
G+P P S + + + P P P PPP P
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278
Query: 738 PVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH----LPS 793
P K G PQ S P P P +G P P P G P
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338
Query: 794 PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
P P P PP + S SR PP PQ PP G N G PPPA
Sbjct: 339 PPPPGKPQGPPPQGGSKSRSARSPP----GKPQGPPQQEG----NNPQGPPPPAG----- 385
Query: 854 APGPPQPPLRPQSQPPEGPLPP----APHLPP 881
G PQ P P + P+GP P P PP
Sbjct: 386 --GNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 63.5 bits (153), Expect = 1e-09
Identities = 67/231 (29%), Positives = 77/231 (33%), Gaps = 56/231 (24%)
Query: 1332 QPPPPPATLKVAEPPPRP--PPPPPPTGQMNGTVDHPPPAAPE-RKPLGTAPHCPRLPLR 1388
Q PPP + PPP P P PPP G N PPP P+ P G PR P
Sbjct: 58 QGPPPQGGNQPQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPPQGDKSRSPRSP-- 114
Query: 1389 KTYRENVGGPGAPEG-TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
PG P+G P G + P P P K +GP
Sbjct: 115 ---------PGKPQGPPPQGGNQPQGPPPPPGKP-----------------------QGP 142
Query: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDS 1507
PP QG P G PP + + P D S SS SP Q
Sbjct: 143 PP-------QGGNKPQ----GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG--- 188
Query: 1508 ILNLQQAPGRTPA-PSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGART 1557
N Q P P P P P PPP +P+ PP N AR+
Sbjct: 189 --NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Score = 56.6 bits (135), Expect = 2e-07
Identities = 59/228 (25%), Positives = 75/228 (32%), Gaps = 22/228 (9%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPL--GTAPHCPRLPLRKT 1390
PPP PPP P PPP G PP P+ P G P P P K
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP 263
Query: 1391 YRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE 1450
G P+G P G P +K + S + +GPPP+
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP-------------QGPPPQ 310
Query: 1451 PAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILN 1510
+ QG P + G PP K + P PQ + + +S
Sbjct: 311 -GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGGSKSRSARSPPGKPQG 368
Query: 1511 LQQAPGRTPAPSYPHAASAGTPASP--PPLHRPEAYPPSSHNGGLGAR 1556
Q G P P A G P P PP +P+ PP GG +R
Sbjct: 369 PPQQEGNNPQGPPPPA--GGNPQQPQAPPAGQPQG-PPRPPQGGRPSR 413
Score = 53.1 bits (126), Expect = 2e-06
Identities = 62/237 (26%), Positives = 75/237 (31%), Gaps = 46/237 (19%)
Query: 1332 QPPPPPATLKV--AEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRK 1389
Q PPP K + PP P PPP G PPP P KP G P P
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPPPQG--GNQPQGPPP--PPGKPQGPPPQGGNKP--- 212
Query: 1390 TYRENVGGPGAPEGTP--------AGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQ 1441
+ PG P+G P + R+ G P P + G
Sbjct: 213 ---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG-------------- 255
Query: 1442 RMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHL 1501
PP +P QG P G PP + + P S SS SP
Sbjct: 256 --PPPPPGKPQGPPPQGGNKPQ----GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309
Query: 1502 QSAIDSILNLQQAPGRTPA-PSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGART 1557
Q N Q P P P P P PPP +P+ PP + AR+
Sbjct: 310 QGG-----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS 361
Score = 50.8 bits (120), Expect = 1e-05
Identities = 117/481 (24%), Positives = 139/481 (28%), Gaps = 94/481 (19%)
Query: 288 VIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRT 347
V Q+ + +A G GG P+ P G+P P G+ P P P +
Sbjct: 23 VSQEESPSLIAGNPQGAPPQGGNKPQGPPS--PPGKPQGPPPQGGNQPQGPPPPPGKPQG 80
Query: 348 PTPIQP-KPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAG 406
P P KP G PP Q P P G P PQ P PQ G
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPP----PQGDKSRSPRSPPGKPQGPP-PQ----------G 125
Query: 407 QNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHML 466
N P P PP P PPG P P Q
Sbjct: 126 GNQPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGP--------------PPQGDN 168
Query: 467 PGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSL 526
++ PG P PQ GG P G P N+ P
Sbjct: 169 KSRSSRSPPGKPQGPPPQ---------GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219
Query: 527 GPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGV 586
P P G + + + P G+P Q P G+ P P P P
Sbjct: 220 KPQGPPPQGDNKSQSARSPP---GKP---QGPPP-QGGNQPQGPPPPPGKPQGP------ 266
Query: 587 TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646
PP N P G P P + +P P P P G QPQ
Sbjct: 267 --PPQGG---NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP--QGPPPQGGNQPQGPP 319
Query: 647 PP----QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQ 702
PP Q P PQ PQ P P G PP + + P
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPGKPQ----------GPPPQGGSKSRSARS------PP 363
Query: 703 ERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL--GPQAPDSQASPAPAP 760
+ Q P EG + PPP P P A AG GP P P+ P
Sbjct: 364 GKPQGPPQQEGNN--------PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Query: 761 Q 761
Q
Sbjct: 416 Q 416
Score = 49.3 bits (116), Expect = 3e-05
Identities = 44/154 (28%), Positives = 51/154 (33%), Gaps = 10/154 (6%)
Query: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPL--GTAPHCPRLPLRKT 1390
PPP PPP P PPP G PP P+ P G P P P K
Sbjct: 266 PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325
Query: 1391 YRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPP- 1449
G P+G P G P +K A S + + E +GPPP
Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE--GNNPQGPPPP 383
Query: 1450 ---EPAASAAQGTGDPDWEAPGLPPAKRRKSESP 1480
P A G P + P PP R S P
Sbjct: 384 AGGNPQQPQAPPAGQP--QGPPRPPQGGRPSRPP 415
Score = 40.4 bits (93), Expect = 0.013
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 12/89 (13%)
Query: 1332 QPPPPPATLKVAEPPP--RPPPPPPPTGQMNGTVDHPP--PAAPERKPLGTAPHCPRLPL 1387
Q PPP K PPP +P PPP G + + PP P P ++ G P P P
Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE-GNNPQGPPPPA 384
Query: 1388 RKTYRENVGGPGAPEGTPAGRARGGSPAP 1416
G P P+ PAG+ +G P
Sbjct: 385 G-------GNPQQPQAPPAGQPQGPPRPP 406
Score = 39.3 bits (90), Expect = 0.030
Identities = 31/101 (30%), Positives = 35/101 (34%), Gaps = 13/101 (12%)
Query: 1332 QPPPPPATLKV--AEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPL--GTAPHCPRLPL 1387
Q PPP K + PP P PPP G PPP P+ P G P P P
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343
Query: 1388 RKTYRENVGG---------PGAPEGTPAGRARGGSPAPLPA 1419
+ GG PG P+G P P PA
Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 100 bits (249), Expect = 1e-20
Identities = 96/313 (30%), Positives = 110/313 (35%), Gaps = 48/313 (15%)
Query: 648 PQAPTPQAAAPPQATTPQPSPGLASSPE----KIVLGQPPSATPTAILTQDSLQMFLPQE 703
PQ P+PQ PQ P P PG P G PP P Q +
Sbjct: 36 PQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG--------D 85
Query: 704 RSQQPLSAEGPHLSVPASVIVSAPPPA---QDPAPATPVAKGAGLGPQAPDSQASPAP-- 758
+S+ P S G PPP Q P P K G PQ + P P
Sbjct: 86 KSRSPRSPPGK---------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136
Query: 759 APQIPAAAPLKGPGPSSSPSLPHQAPL--GDSPHLPSPHPTRPPSRPPSRPQSVSRPPSE 816
PQ P K P S P P P G+ P P P P +P PP + PP
Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP-- 194
Query: 817 PPLHP-CPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875
PP P PPPQ + G PP N GPP PP +PQ PP+G P
Sbjct: 195 PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKP 251
Query: 876 APHLPPSSTSS--AVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPE-- 931
PP A S S+R P P Q PP Q + PPP P+
Sbjct: 252 QGPPPPGKPQGPPAQGGSKSQSARSPPGKP-----QGPPQQEGNNPQGPPPPAGGNPQQP 306
Query: 932 ---PAAPPPPPPR 941
PA P PPR
Sbjct: 307 QAPPAGQPQGPPR 319
Score = 88.6 bits (218), Expect = 4e-17
Identities = 82/318 (25%), Positives = 107/318 (33%), Gaps = 46/318 (14%)
Query: 730 AQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSP 789
+Q+ +P+ G PQ + P P P P P +G P P + P G
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPP- 81
Query: 790 HLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849
P +R P PP +PQ PP PQ PP PG G PP N
Sbjct: 82 --PQGDKSRSPRSPPGKPQG-------PPPQGGNQPQGPPPPPG-----KPQGPPPQGGN 127
Query: 850 PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ 909
P P PP +PQ PP+G +P PP + ++ P P + Q
Sbjct: 128 ----RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ---GPPPQGGNQPQGPPPPPGKPQ 180
Query: 910 FPPSQGPHKSPTPPPTLHLVPEPAAPPP-----------------PPPRTFQMVTTPFPA 952
PP QG K PPP +P PPP PPP+ P P
Sbjct: 181 GPPPQGGKKPQGPPPP----GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
Query: 953 LPQPKALLERFHQVPSGIILQNKAGGAPA--APQTSTSLGPLTSPAASVLVSGQAPSGTP 1010
+P+ + P G K G PA ++ ++ P P G P G P
Sbjct: 237 PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 296
Query: 1011 TAPSHAPAPAPMAATGLP 1028
P G P
Sbjct: 297 PPAGGNPQQPQAPPAGQP 314
Score = 81.3 bits (199), Expect = 7e-15
Identities = 80/299 (26%), Positives = 106/299 (35%), Gaps = 41/299 (13%)
Query: 774 SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPG 833
SS+ +L +SP L + +P P + ++PQ PP +P PPPQ
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP---QGPPPQGG----- 65
Query: 834 IFVIQNQLGVPPPASNPAPTAPG-----PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAV 888
G PPP P G P PP +PQ PP+G P PP
Sbjct: 66 ----NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQ 119
Query: 889 ASSSETSSRLPAPTPSDFQLQFPPSQG-PHKSPTPPPTLHLVP------EPAAPPPPPPR 941
+ +R P P + Q PP QG +SP PP P +P PPPPP +
Sbjct: 120 GPPPQGGNRPQGPPPPG-KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178
Query: 942 TFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLV 1001
P P P+ + P G G P ++ +S P P
Sbjct: 179 ---------PQGPPPQGGKKPQGPPPPG----KPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225
Query: 1002 SGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSG 1060
G P G P P P P P P K + +++A S PGKP G
Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG 283
Score = 57.0 bits (136), Expect = 1e-07
Identities = 62/236 (26%), Positives = 78/236 (33%), Gaps = 16/236 (6%)
Query: 1332 QPPPPPATLKVAEPPPRP--PPPPPPTGQMNGTVDHPPPAAPE-RKPLGTAPHCPRLPLR 1388
Q PPP + PPP P P PPP G N PPP P+ P G PR P
Sbjct: 98 QGPPPQGGNQPQGPPPPPGKPQGPPPQGG-NRPQGPPPPGKPQGPPPQGDKSRSPRSPPG 156
Query: 1389 KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPP 1448
K G P+G P + P P K + + R + PP
Sbjct: 157 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP 216
Query: 1449 PEPAASAAQGTGDPDWEAP------GLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQ 1502
+P QG P P G PP K + P Q + ++ +
Sbjct: 217 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPAQGGSKSQSAR 275
Query: 1503 SAIDSILNLQQAPGRTPAPSYPHAASAGTPASP--PPLHRPEAYPPSSHNGGLGAR 1556
S Q G P P A G P P PP +P+ PP GG +R
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPA--GGNPQQPQAPPAGQPQG-PPRPPQGGRPSR 328
Score = 56.2 bits (134), Expect = 2e-07
Identities = 66/249 (26%), Positives = 89/249 (35%), Gaps = 46/249 (18%)
Query: 1333 PPPPPATLKVAEPPPR---PPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRK 1389
PPPPP K PPP+ P PPP G+ G PPP + + + P P+ P +
Sbjct: 50 PPPPPG--KPQGPPPQGGNKPQGPPPPGKPQG----PPPQGDKSRSPRSPPGKPQGPPPQ 103
Query: 1390 TYRENVG---GPGAPEGTP---AGRARG----GSPAPLPAKVDEATSGLIRELAAVEDEL 1439
+ G PG P+G P R +G G P P + D++ S
Sbjct: 104 GGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS----------PRS 153
Query: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSES----------PDVDQASFSS 1489
+GPPP+ + QG P + G PP +K + P S SS
Sbjct: 154 PPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS 212
Query: 1490 DSPQDDTLTEHLQSAIDSILNLQQAPGRTPA-PSYPHAASAGTPASPPPLHRPEAYPPSS 1548
SP Q N Q P P P P P PPP +P+ P
Sbjct: 213 QSPPGKPQGPPPQGG-----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQG 267
Query: 1549 HNGGLGART 1557
+ AR+
Sbjct: 268 GSKSQSARS 276
Score = 47.0 bits (110), Expect = 1e-04
Identities = 51/177 (28%), Positives = 58/177 (32%), Gaps = 22/177 (12%)
Query: 599 PDGLVQPATPAAATGEA-APVLTVQPAPQAPPAVSTPL---PLGLQQPQAQQPP---QAP 651
P G QP P G+ P PQ PP P P G + +Q PP Q P
Sbjct: 163 PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGP 222
Query: 652 TPQAAAPPQATTPQPSPGLASSPE--KIVLGQPPSATPTAILTQD---SLQMFLPQERSQ 706
PQ PQ P P P+ G PP P Q S P + Q
Sbjct: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQ 282
Query: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL--GPQAPDSQASPAPAPQ 761
P EG + PPP P P A AG GP P P+ PQ
Sbjct: 283 GPPQQEGNN--------PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 35.4 bits (80), Expect = 0.43
Identities = 92/388 (23%), Positives = 106/388 (27%), Gaps = 82/388 (21%)
Query: 288 VIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRT 347
V Q+ + +A G S GG P P G+P P G+ P P P
Sbjct: 23 VSQEESPSLIAGNPQGPSPQGGNKPQGPPP--PPGKPQGPPPQGGNKPQGPPP------- 73
Query: 348 PTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQ 407
KP G PP + P +P G + G PQ P P + G
Sbjct: 74 ----PGKPQG--PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127
Query: 408 NVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLP 467
G P P PP +P PPG P P Q
Sbjct: 128 RP--QGPPPPGKPQG---PPPQGDKSRSPRSPPGKPQGP--------------PPQ---- 164
Query: 468 GQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG 527
G NQ PQ P G P GG+ P P
Sbjct: 165 GGNQ-----------PQGPPPPPGKPQGP------PPQGGKKPQGP---------PPPGK 198
Query: 528 PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT 587
P P G S S G P G+ P P P P
Sbjct: 199 PQGPPPQGDKSRSSQSPPGKPQGPPP--------QGGNQPQGPPPPPGKPQGP------- 243
Query: 588 LPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPA-PQAPPAVSTPLPLGLQQPQAQQ 646
PP P +P P A G + P PQ PP P G P A
Sbjct: 244 -PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG-PPPPAGG 301
Query: 647 PPQAPTPQAAAPPQATTPQPSPGLASSP 674
PQ P A PQ P G S P
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,738,942
Number of Sequences: 37866
Number of extensions: 7300435
Number of successful extensions: 155047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1044
Number of HSP's successfully gapped in prelim test: 2993
Number of HSP's that attempted gapping in prelim test: 36521
Number of HSP's gapped (non-prelim): 52989
length of query: 1560
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1444
effective length of database: 13,855,062
effective search space: 20006709528
effective search space used: 20006709528
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.