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Search of human proteins with 163310745
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163310745 LIM and calponin homology domains 1 isoform c
[Homo sapiens]
(1056 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 2124 0.0
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 2119 0.0
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 2105 0.0
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 1803 0.0
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 1768 0.0
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 451 e-126
gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] 168 3e-41
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 73 1e-12
gi|4502923 calponin 3 [Homo sapiens] 73 1e-12
gi|41327730 calponin 2 isoform b [Homo sapiens] 68 5e-11
gi|4758018 calponin 2 isoform a [Homo sapiens] 65 3e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 3e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 59 3e-08
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 57 7e-08
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 56 2e-07
gi|238908501 sciellin isoform 3 [Homo sapiens] 55 5e-07
gi|238908499 sciellin isoform 1 [Homo sapiens] 55 5e-07
gi|238908497 sciellin isoform 2 [Homo sapiens] 55 5e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 54 1e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 54 1e-06
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 53 2e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 4e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 49 2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 49 2e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 49 2e-05
gi|148746195 trichohyalin [Homo sapiens] 49 3e-05
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 2124 bits (5503), Expect = 0.0
Identities = 1056/1056 (100%), Positives = 1056/1056 (100%)
Query: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA
Sbjct: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
Query: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS
Sbjct: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
Query: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI
Sbjct: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
Query: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR
Sbjct: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
Query: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST
Sbjct: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
Query: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE
Sbjct: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
Query: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE
Sbjct: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
Query: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL
Sbjct: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
Query: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP
Sbjct: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG
Sbjct: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ
Sbjct: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
Query: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE
Sbjct: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
Query: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQ 780
PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQ
Sbjct: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQ 780
Query: 781 QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQ 840
QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQ
Sbjct: 781 QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQ 840
Query: 841 LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTE 900
LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTE
Sbjct: 841 LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTE 900
Query: 901 GALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTL 960
GALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTL
Sbjct: 901 GALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTL 960
Query: 961 PLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKG 1020
PLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKG
Sbjct: 961 PLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKG 1020
Query: 1021 QLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
QLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1021 QLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 2119 bits (5491), Expect = 0.0
Identities = 1056/1057 (99%), Positives = 1056/1057 (99%), Gaps = 1/1057 (0%)
Query: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA
Sbjct: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
Query: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS
Sbjct: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
Query: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI
Sbjct: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
Query: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR
Sbjct: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
Query: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST
Sbjct: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
Query: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE
Sbjct: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
Query: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE
Sbjct: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
Query: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL
Sbjct: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
Query: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP
Sbjct: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG
Sbjct: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ
Sbjct: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
Query: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE
Sbjct: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
Query: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP-FKFWAWDPEEERRRQEKW 779
PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP FKFWAWDPEEERRRQEKW
Sbjct: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
Query: 780 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 839
QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD
Sbjct: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
Query: 840 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 899
QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT
Sbjct: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
Query: 900 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 959
EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT
Sbjct: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
Query: 960 LPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICK 1019
LPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICK
Sbjct: 961 LPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICK 1020
Query: 1020 GQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
GQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1021 GQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1057
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 2105 bits (5454), Expect = 0.0
Identities = 1056/1083 (97%), Positives = 1056/1083 (97%), Gaps = 27/1083 (2%)
Query: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA
Sbjct: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
Query: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS
Sbjct: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
Query: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI
Sbjct: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
Query: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR
Sbjct: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
Query: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST
Sbjct: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
Query: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE
Sbjct: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
Query: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE
Sbjct: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
Query: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL
Sbjct: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
Query: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP
Sbjct: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG
Sbjct: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ
Sbjct: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
Query: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE
Sbjct: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
Query: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP-FKFWAWDPEEERRRQEKW 779
PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP FKFWAWDPEEERRRQEKW
Sbjct: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
Query: 780 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 839
QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD
Sbjct: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
Query: 840 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 899
QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT
Sbjct: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
Query: 900 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 959
EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT
Sbjct: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
Query: 960 LPLDKSINHQIESPSERRK--------------------------SISGKKLCSSCGLPL 993
LPLDKSINHQIESPSERRK SISGKKLCSSCGLPL
Sbjct: 961 LPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPL 1020
Query: 994 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1053
GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP
Sbjct: 1021 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1080
Query: 1054 TTL 1056
TTL
Sbjct: 1081 TTL 1083
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 1803 bits (4669), Expect = 0.0
Identities = 895/895 (100%), Positives = 895/895 (100%)
Query: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
Query: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
Query: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP
Sbjct: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
Query: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 188 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
Query: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 368 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 427
Query: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 428 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 487
Query: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 488 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 547
Query: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 548 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 607
Query: 762 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 821
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER
Sbjct: 608 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 667
Query: 822 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 881
KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD
Sbjct: 668 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 727
Query: 882 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 941
LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ
Sbjct: 728 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 787
Query: 942 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 1001
NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII
Sbjct: 788 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 847
Query: 1002 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 848 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 902
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 1768 bits (4580), Expect = 0.0
Identities = 883/895 (98%), Positives = 883/895 (98%), Gaps = 12/895 (1%)
Query: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
Query: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
Query: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
APLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCEEEAAVQP
Sbjct: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCEEEAAVQP 175
Query: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 176 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 235
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 236 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 296 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 355
Query: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 356 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 415
Query: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 416 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 475
Query: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 476 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 535
Query: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 536 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 595
Query: 762 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 821
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER
Sbjct: 596 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
Query: 822 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 881
KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD
Sbjct: 656 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 715
Query: 882 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 941
LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ
Sbjct: 716 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 775
Query: 942 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 1001
NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII
Sbjct: 776 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 835
Query: 1002 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 836 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 451 bits (1160), Expect = e-126
Identities = 329/984 (33%), Positives = 507/984 (51%), Gaps = 144/984 (14%)
Query: 31 IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90
I+ VT ++F KDFR LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+
Sbjct: 74 IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133
Query: 91 ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150
++GLKE+QLF P DLQD SNRVTVK + R++KNVL+T+YWLG+ A S Y+G LNL
Sbjct: 134 QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193
Query: 151 KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208
K FE LL Q + K +D KRS RDSGY D W ER + L+PPR H R+DSF+SLDS
Sbjct: 194 KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253
Query: 209 GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268
GSRS + S D+ LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN+
Sbjct: 254 GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312
Query: 269 YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326
+LPNKS Q +YVPAPLRKKK ++ E+ R+SW+ SP+ E + + + S
Sbjct: 313 FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369
Query: 327 SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386
SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+
Sbjct: 370 SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
Query: 387 EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445
EER+++EK + ++S KT++E++Q++E + ++ + R + +L++
Sbjct: 427 EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479
Query: 446 -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499
T+SEA ER+E S + + ++F + + L QS +
Sbjct: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539
Query: 500 TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556
A++ + +R++ ++++ + S S KT T + ++TP+P+ SQ + + +++ +
Sbjct: 540 PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599
Query: 557 DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583
D NG E EE+ R +P
Sbjct: 600 DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659
Query: 584 HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642
SL++ Q A + S L+L ++G EI S +E++ + ++
Sbjct: 660 SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713
Query: 643 DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699
GKS + P F +V SP F + + + N D K+ E
Sbjct: 714 TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772
Query: 700 EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737
M+ E LV+ ++ K SPE + ++T F + + +N
Sbjct: 773 AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832
Query: 738 --------------------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWD 768
+ L NL SQ S S P ++ W WD
Sbjct: 833 SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWD 892
Query: 769 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 828
EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++
Sbjct: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952
Query: 829 VPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQ 867
+ T S S+D+ T + E ++ D G QD+ ++
Sbjct: 953 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012
Query: 868 DRRWKKSFQGDDSDLLLKTRESDR 891
+R+W++ Q + L+ ++
Sbjct: 1013 ERKWEQQLQEEQEQKRLQAEAEEQ 1036
Score = 113 bits (282), Expect = 1e-24
Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 827
E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++
Sbjct: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
Query: 828 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 862
+P T +SS D+ + S+ T +G +D +GN
Sbjct: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
Query: 863 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 913
Q Q+ R + D+S + ++ ++ + G + G +L + +P S
Sbjct: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
Query: 914 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 960
+ L+ G + ++ P Q TSN P S+ VK T +
Sbjct: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
Query: 961 PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 1013
+S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF
Sbjct: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307
Query: 1014 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
+C C+ LG + SG +VRIRN L CNDCY+R +S G+PT +
Sbjct: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
Score = 31.6 bits (70), Expect = 4.1
Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)
Query: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
Query: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
Query: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
Query: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
Query: 532 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559
+P P S P SQ L+ V GK
Sbjct: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
>gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
Length = 1385
Score = 168 bits (425), Expect = 3e-41
Identities = 188/765 (24%), Positives = 329/765 (43%), Gaps = 149/765 (19%)
Query: 246 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 305
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
Query: 306 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 365
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
Query: 366 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 425
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
Query: 426 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 481
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
Query: 482 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 536
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
Query: 537 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 564
TP+P+ SQ + + +++ +D NG
Sbjct: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
Query: 565 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 621
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
Query: 622 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 681
+E++ + ++ GKS + P F +V SP F +
Sbjct: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
Query: 682 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 722
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
Query: 723 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 754
++T F + + +N + L NL SQ S
Sbjct: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
Query: 755 KS-------PVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK 807
S P ++ W WD EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++
Sbjct: 921 DSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ 980
Query: 808 EVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGSGT 853
E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 981 EAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQP 1040
Query: 854 MNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 891
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 1041 QEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
Score = 77.0 bits (188), Expect = 9e-14
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 242 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 300
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
Score = 38.1 bits (87), Expect = 0.044
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 769 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 822
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
Score = 36.2 bits (82), Expect = 0.17
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 207 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 262
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
Query: 263 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 298
F+Q+LP + P + K+ +RE Y K W
Sbjct: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
Score = 35.0 bits (79), Expect = 0.37
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 775 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
Query: 832 TVSSSS 837
T +SS
Sbjct: 1121 TEEASS 1126
Score = 33.1 bits (74), Expect = 1.4
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
Query: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
Query: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
Query: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
Query: 532 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 590
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
Query: 591 M 591
+
Sbjct: 1356 L 1356
>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
Length = 297
Score = 73.2 bits (178), Expect = 1e-12
Identities = 37/91 (40%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Query: 26 EAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILF 85
E ++WIE VTGR G+ +F GL++GI+LCE +N ++PG VKKIN L+NI F
Sbjct: 33 ELREWIEGVTGRRIGN-NFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNF 91
Query: 86 LRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
++ + G+K +F+ +DL + +N V+S
Sbjct: 92 IKAITKYGVKPHDIFEANDLFENTNHTQVQS 122
>gi|4502923 calponin 3 [Homo sapiens]
Length = 329
Score = 73.2 bits (178), Expect = 1e-12
Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Query: 23 AFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNI 82
A + + WIE+VTG S G +F+ GL++GI+LCEL+N ++PG VKK+N L+NI
Sbjct: 28 AEEDLRNWIEEVTGMSIGP-NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENI 86
Query: 83 ILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
F++ + G+K +F+ +DL + N V++
Sbjct: 87 GNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
>gi|41327730 calponin 2 isoform b [Homo sapiens]
Length = 270
Score = 67.8 bits (164), Expect = 5e-11
Identities = 43/125 (34%), Positives = 65/125 (52%), Gaps = 15/125 (12%)
Query: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
Query: 85 FLRGCKELGLKESQLFDPSDLQDTSN--RVTVKSLDYSRKLKNVLVTIYWLGKAANSCTS 142
F++ G+ LF+ +DL ++ N +V V L + K+ N C S
Sbjct: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKM------------GTNKCAS 138
Query: 143 YSGTT 147
SG T
Sbjct: 139 QSGMT 143
>gi|4758018 calponin 2 isoform a [Homo sapiens]
Length = 309
Score = 65.5 bits (158), Expect = 3e-10
Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Query: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
Query: 85 FLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
F++ G+ LF+ +DL ++ N V+
Sbjct: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQ 121
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.5 bits (140), Expect = 3e-08
Identities = 99/526 (18%), Positives = 209/526 (39%), Gaps = 57/526 (10%)
Query: 332 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 387
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 388 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQE------ 437
E ++ ++L E+ E+ + + E ++E+E R+E L E K R QE
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 438 -----EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQ 492
E + L++ ER E + E++E + ++ E + +R++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 493 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLK 552
K ET + + K + +P K + Q K + K
Sbjct: 456 E---KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 553 TFKVDGKVSVNGETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQ 607
++ + K+ E +E +EK RE + QM+E ++ ++
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWD 562
Query: 608 DNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVT 667
+E ++ QE ++ + +E + K + E+ + +
Sbjct: 563 QEERMEKKTQE-----QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 668 RCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTF 727
+ + K EEK Q++ E + ++ ++ + + PE
Sbjct: 618 KMQ----------EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 728 PFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP---EEERRRQEKWQQEQE 784
+KM E ++ + EK K W + EE R +EK +E+E
Sbjct: 668 WEHEKMQEQEKMQEQE-EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 785 RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVP 830
+++E+ +K Q++ +E+ ++ ++E+ E+E + +E+E K+ E +P
Sbjct: 727 EMMREQEEKMQEQ-EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/162 (21%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 344
R +K +E+ +K+W ER + ++ M+ +EE + +
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 345 A--RQEQLQLINNQLREEDDK-WQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
++E++Q ++ E+++K W+ + W+ +R ++ + + E+ ++ EK+ E+
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 402 TSERRKSIKTYREIV-----QEKERRERELHEAYKNARSQEE 438
E+ K K +E QEK R E + E K R +EE
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/140 (21%), Positives = 66/140 (47%), Gaps = 17/140 (12%)
Query: 767 WDPEEERRRQEK---------WQQEQERLLQERYQKEQDKLKEEWEK--AQKEVEEEERR 815
W+ E++ R QE+ W+Q++ +E +EQ+K+ E+ EK +K+++E+E++
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 816 YYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSF 875
++E K+ E+ + +M E M K + E++++ W++
Sbjct: 439 TRDQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQR 492
Query: 876 QGDDSDLLLKTRESDRLEEK 895
+ + L + + EEK
Sbjct: 493 LPEQKEKLWEQEKMQEQEEK 512
Score = 43.9 bits (102), Expect = 8e-04
Identities = 44/225 (19%), Positives = 99/225 (44%), Gaps = 21/225 (9%)
Query: 690 EEKDQK-KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHL------- 741
E++DQ + E +M + + + Q+ K + + T+ +KM E ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 742 -PNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQDKL 798
+ + + E+ M + W+ EE+ + QE+ W+QE++ QE EQ +L
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 799 KEEWEK--------AQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEG 850
E+ EK Q++++E+E + +E+E+ +E + +++ SM E
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK--MEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 851 SGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 895
M + + + E++ + ++ Q + ++ + + EEK
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Score = 43.5 bits (101), Expect = 0.001
Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 9/147 (6%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 390
+R +EE Q RQE+++ +Q+ E+++K +D + + + + ++E++
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 391 KMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY---------KNARSQEEAEG 441
E+ + E+ ER K ++ E+++E+E + +E E + + QE+ E
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 442 ILQQYIERFTISEAVLERLEMPKILER 468
+ +Q + + E + E+ +P+ E+
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 699 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQV--------DS 750
NE K L +K+ +S + E L L + E + LP + + +
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 279
Query: 751 PSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLL--QERYQKEQDKLKEEWEK---A 805
E+ + + W EE R QE +EQE + QE+ +EQ+K E EK
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 806 QKEVEEEERRYYEEERKIIE 825
QKE+ E+E + E+E K+ E
Sbjct: 340 QKELREQEEQMQEQEEKMWE 359
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 23/137 (16%)
Query: 768 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEERKII 824
+ EE R QE+ QEQE E+ Q++++K+ E+ EK Q++ E E+E + +E+E K+
Sbjct: 600 EEEEMMREQEEKMQEQE----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 825 EDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRW-KKSFQGDDSDLL 883
E +P ++L M E E++++ W ++ + +
Sbjct: 656 EQQRLP-----EQKEKLWEHEKMQEQEK----------MQEQEEKIWEQEKMEKKTQEQE 700
Query: 884 LKTRESDRLEEKGSLTE 900
KT + +++ E+ S+ E
Sbjct: 701 KKTWDQEKMREEESMRE 717
Score = 39.7 bits (91), Expect = 0.015
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 23/148 (15%)
Query: 691 EKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDS 750
E +K P E S K E+ L+ K +K K + FL + N L + +
Sbjct: 229 ELQEKLPLAE-SEKSEIQLNVKELKRKLERAK------FLLPQVQTNTLQEEMWRQEEEL 281
Query: 751 PSSEKSPVMTPFKFWAWDPEEERRRQEK----------WQQEQERLLQERYQKEQDK-LK 799
EK K W +EER R+++ W+QE+ QE+ +EQ+K L+
Sbjct: 282 REQEKKIRKQEEKMWR---QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 800 EEWEKAQKE--VEEEERRYYEEERKIIE 825
E+ E ++E ++E+E + +E+E K+ E
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMRE 366
Score = 39.3 bits (90), Expect = 0.020
Identities = 76/483 (15%), Positives = 187/483 (38%), Gaps = 29/483 (6%)
Query: 344 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKK-MEKLLAGEDGT 402
R ++E++ + +LRE++++ ++ W+ + + ++++E++ + E+ + E+
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI 452
Query: 403 SERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 462
ER K ++ E ++E+E + ++ E +E + L + E+ E + E+ E
Sbjct: 453 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE- 511
Query: 463 PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSG 522
KI E+ + + + + + + + + D
Sbjct: 512 -KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD-------- 562
Query: 523 SPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAP 582
+ K K + Q + ++ + + + K+ E + +EEK +E
Sbjct: 563 --QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 583 AHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642
+ E + E ++ E + + +P++ E + QE
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 643 DGGKS--RKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENE 700
+ + + +E + E + T + + E + + ++ E+++K E E
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 701 --MSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPV 758
M + E + Q+ K E E + ++PE + + Q E+
Sbjct: 741 EKMQEQEEEMWEQE---EKMWEQEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKIWEQEEK 795
Query: 759 MTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYE 818
M D EE+ R QE+ + QE ++ + +K + ++ W + +K +EE+ + +
Sbjct: 796 MR-------DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 819 EER 821
EE+
Sbjct: 849 EEK 851
Score = 38.9 bits (89), Expect = 0.026
Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 5/127 (3%)
Query: 770 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 828
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE +++ R E++ K+ E
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ--RLPEQKEKLWEQEK 505
Query: 829 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 888
+ +Q E G K+ E++D+ W++ + D + + +E
Sbjct: 506 MQ-EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 889 SDRLEEK 895
+R+E+K
Sbjct: 565 -ERMEKK 570
Score = 38.5 bits (88), Expect = 0.034
Identities = 30/175 (17%), Positives = 83/175 (47%), Gaps = 16/175 (9%)
Query: 284 LRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS 343
LR+K+ E K W E+ + + + + T + + +EE ++
Sbjct: 406 LREKEERMREQEKMW---------EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 344 RARQEQLQLINNQ----LREEDDKWQDDLARWKSRRRSVSQD-LIKKEEERKKMEKLLAG 398
+ +E+ + + Q ++E++ W+ + W+ +R ++ L ++E+ +++ EK+
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 399 EDGTSERRKSIKTYREIVQEKERRERE--LHEAYKNARSQEEAEGILQQYIERFT 451
E+ ++ + +++ ++++ RE+E + E + R QE+ ++ +E+ T
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Score = 36.6 bits (83), Expect = 0.13
Identities = 18/60 (30%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query: 767 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKI 823
W EE+ QE+ QE ++E+ Q +++K++E+ EK ++++ E+E + +E KI
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 35.8 bits (81), Expect = 0.22
Identities = 20/99 (20%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLRE----EDDKWQDDLARWKSRRRSVSQDLIKKEEER 389
EEE ++ QEQ + + Q E E+ W+ + W+ +R ++ + + E+
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 390 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 428
++ EK+ E+ ++ + ++ E ++ +E + R E
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 35.0 bits (79), Expect = 0.37
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 768 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDT 827
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 828 VVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTR 887
+ +++ M E M + + + EK+ R ++ Q ++ ++ R
Sbjct: 405 RL-----REKEERMREQEKMWEQVEKMRE-EKKMQEQEKKTRDQEEKMQEEER---IRER 455
Query: 888 ESDRLEEKGSLTE 900
E EE+ ++ E
Sbjct: 456 EKKMREEEETMRE 468
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/125 (20%), Positives = 64/125 (51%), Gaps = 10/125 (8%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQ-LREEDDKWQDDLARWKSRRRSVSQDLIKKEEE- 388
MR +EE + R R+++ ++ + + E+ +K +++ + +++ Q+ +EEE
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 389 -RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE-------RELHEAYKNARSQEEAE 440
R++ +K+ E+ E+ + ++ E + E+E +E + + ++ + QE+ E
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 441 GILQQ 445
I +Q
Sbjct: 512 KIWEQ 516
Score = 32.3 bits (72), Expect = 2.4
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDK-WQDDLARWKSRRRSVSQDLIKKEEER 389
MR +EE R ++E+++ ++R +++K W + W + Q+ +E
Sbjct: 796 MRDQEEKM-----RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 390 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 428
K EK+ E+ E+ + ++ E ++E+E + R E
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 31.2 bits (69), Expect = 5.4
Identities = 26/142 (18%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Query: 322 DAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLRE-EDDKWQDDLARWKSRRRSVSQ 380
+AE + E++ +Q + + + +L+ L + + + Q+++ R + R +
Sbjct: 227 NAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 286
Query: 381 DLIKKEEERKKMEKLLAGEDGTS-ERRKSIKTYREIVQEKERRERELHEAYKNARSQEEA 439
+ K+EE+ + E+ L ++G E+ + + + ++E+E+ RE + + + E
Sbjct: 287 KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 440 EGILQQYIERFTISEAVLERLE 461
E +Q+ E+ E + E
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQE 368
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 58.5 bits (140), Expect = 3e-08
Identities = 137/612 (22%), Positives = 221/612 (36%), Gaps = 81/612 (13%)
Query: 383 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 442
+K EE+ K +EK E+ + + E+ +E+E+ +E + +EEAEG
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG 497
Query: 443 LQQY----IERFTISE-----AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQS 493
++ E E V E + P + E + + P K ++
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 494 LPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKT 553
P + E A++ A SP K +P +P P+ ++ +K
Sbjct: 558 AKSPPEAKSPEKEEAKS-------PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 554 FKVDGKVSVNGETVHREEEKE-RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI 612
+ K ++ +EE K E + A S TK + SP + K
Sbjct: 611 ---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA--------KSPEKAKSP---- 655
Query: 613 EINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT 672
+K + E A + K E S E K+ + E A S + + +
Sbjct: 656 ----EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 673 VAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDK 732
V E S + K+ V EE K PE S E S + K KSPE TL K
Sbjct: 712 VK-EEAKSPEKAKSPVKEE--AKTPEKAKSPVKEEAKSPE--KAKSPEKAKTLDV----K 762
Query: 733 MPEANQLHLPNLNSQVDS-PSSEKSPV----------MTPFKFWAWDPEEE--RRRQEKW 779
PEA S D P KSPV +P K A PE+E ++ + K
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS 822
Query: 780 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 839
++E QE KE K EE EKA + EE++ ++E ++ P
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEE-EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 840 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 899
S E ++E +D++ K ++ ++ +E + +EK T
Sbjct: 882 VEKPKESKVEAK-----------KEEAEDKK-KVPTPEKEAPAKVEVKEDAKPKEK---T 926
Query: 900 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT------SNPTHSSE 953
E A + +K + + EA T + A+ P + +T + T S E
Sbjct: 927 EVAKKEPDDAKAKEPSKPAE-KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Query: 954 DVKPKTLPLDKS 965
KPK +KS
Sbjct: 986 PSKPKAEKAEKS 997
Score = 52.0 bits (123), Expect = 3e-06
Identities = 108/551 (19%), Positives = 205/551 (37%), Gaps = 68/551 (12%)
Query: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
+P K E+EE KS + SP + P + ++P + E ++ +
Sbjct: 526 SPAEAKSPEKEE-AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
S A++E + E+ + A+ + +S ++ K E K EK +
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK---AKSP 641
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
T E KS ++ + E+E ++ + A+S +AE + + +EA
Sbjct: 642 TKEEAKS-------PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
+ E + S E S +++++ P K + V+ + + +
Sbjct: 695 KSPVKEEAKSPEKAKSP----------VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 522 GSPSKTVTP---KAVPMLTPKPYSQPKN-SQDVLKTFKVDGKVSVNGETVHREEEKER-E 576
SP K +P K + + +P+ + K ++ F K V E E+ K +
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Query: 577 CPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPN 636
AP + K + + + P E+K + P +E A T KTE
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK--------EPPKKAEEEKAPATPKTEEK 856
Query: 637 SQEDKNDGGKSR--KGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 694
K + K K +E EP VE P +++ E +D+
Sbjct: 857 KDSKKEEAPKKEAPKPKVE-EKKEPA---------------VEKPKESKVEAKKEEAEDK 900
Query: 695 KK---PENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSP 751
KK PE E KVE+ ++ KPK A K P+ + P+ ++
Sbjct: 901 KKVPTPEKEAPAKVEV---KEDAKPKEKTEVAK-------KEPDDAKAKEPSKPAEKKEA 950
Query: 752 SSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE 811
+ EK A PEE+ + + K +++ + L +E + + +K ++ QK+ +
Sbjct: 951 APEKKDTKEEK---AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Query: 812 EERRYYEEERK 822
E+ ++ K
Sbjct: 1008 PEKATEDKAAK 1018
Score = 46.6 bits (109), Expect = 1e-04
Identities = 88/454 (19%), Positives = 164/454 (36%), Gaps = 31/454 (6%)
Query: 214 QTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMS---ARRTSHGEPKSAVPFNQYL 270
+ SP+ + + S +E+ P + VK++ S A+ E KS
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE 636
Query: 271 PNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFD 330
KS +P + K E+EE KS A SP+ E ++PV +A+S
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEE-AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 331 MRCEEEA--------AVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDL 382
+EEA V+ +++ ++ + + + + KS ++ S +
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 383 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 442
K + + K A E+ S K + + V+E+ + + K E E
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP 815
Query: 443 LQQYIERFTISEAVLERL---EMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKF 499
++ ++ E + + E PK E + + D + ++++ P PK
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA-PKPKV 874
Query: 500 TATVETTIARASVLDTSMSAGSGSPSKTV-TP--KAVPMLTPKPYSQPKNSQDVLKTFKV 556
E + + K V TP +A + K ++PK +V K
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 557 DGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINI 616
D K +E K E AP TK + + + + K+D+ ++
Sbjct: 935 DAKA--------KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 617 KKPNSVPQELAATTE----KTEPNSQEDKNDGGK 646
KP + E +++T+ K + EDK GK
Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 32.0 bits (71), Expect = 3.2
Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 741 LPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKE 800
+P++++ + S EK V+ + E+ + Q E+ ++ +E ++E+ + KE
Sbjct: 429 IPSVSTHIKVKSEEKIKVV--------EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 801 EWEKAQKEVEEEERRYYEEERK 822
E K ++ EEEE EEE K
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETK 502
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 57.4 bits (137), Expect = 7e-08
Identities = 170/861 (19%), Positives = 333/861 (38%), Gaps = 149/861 (17%)
Query: 90 KELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLN 149
+E L + Q+ D D S RVT L R K L T
Sbjct: 377 REKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNL----------EKDQVNKDLTEK 426
Query: 150 LKEFEGLLAQMRK--DTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDS 207
L+ E L Q + +T+D E ++++RD DSE LS D S SL
Sbjct: 427 LEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLR- 485
Query: 208 FGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFN 267
G ++TPSP R SS GRG R+ P A
Sbjct: 486 -GLSGQRTPSPP---RRSSPGRG-----------------------RSPRRGPSPAC--- 515
Query: 268 QYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTS 327
+ S+ A + + L K++ + ++ R + + LG R +SD
Sbjct: 516 ----SDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLG-------TLRKQLSDSESERR 564
Query: 328 MFD-----MRCEEEAAVQPHSRARQE--QLQLINNQLREEDD---------KWQDDLARW 371
+ +R + + A+Q H A++E +L+ N L E + Q + R
Sbjct: 565 ALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQ 624
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE------RE 425
+ + +Q+ ++++ +R + E+ A +DG RR+ +++R++ Q + +R E
Sbjct: 625 EREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE 684
Query: 426 LHEAYKNARSQEEAEGILQQYIERFTISEAVLE----RLEMPKILERSHSTEPNLSSFLN 481
+ EA A Q + +LQ E+ ++EA+ + R+E+ + + + E +L L+
Sbjct: 685 VREALSRATLQRD---MLQ--AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS 739
Query: 482 DPNPM-KYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
+ + + L Q L + A L+ SA G + V +
Sbjct: 740 KLSALNESLAQDKLDLNRLVAQ----------LEEEKSALQGRQRQAEQEATVAREEQER 789
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
+ + Q+V + ++G + V + +E E++ PT+ S + Q+ + ++ G
Sbjct: 790 LEELRLEQEVARQ-GLEGSLRVAEQA---QEALEQQLPTLRHERSQLQEQLAQLSRQLSG 845
Query: 601 SPLELKQDN-------GSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIE 653
EL+Q ++E ++ ++ +E A + +E + ++ + +E
Sbjct: 846 REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLE 905
Query: 654 LASSEPQHFTTTVTRCSPTVAFVEFPSSPQ--------LKNDVSEEKDQKKPENEMSGKV 705
+ E F + + Q L +++ + Q E +
Sbjct: 906 KEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLD 965
Query: 706 ELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFW 765
+ +++QK+V+ + E +A+L + A++ L L + ++ W
Sbjct: 966 KELMAQKLVQAER-EAQASLR-----EQRAAHEEDLQRLQREKEAA-------------W 1006
Query: 766 AWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 825
E + Q + Q+EQE LL R + E+++L EE Q+E +E ++
Sbjct: 1007 RELEAERAQLQSQLQREQEELL-ARLEAEKEELSEEIAALQQE---------RDEGLLLA 1056
Query: 826 DTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLK 885
++ +S +++ + S + GT + + + + E+Q R + + D S +
Sbjct: 1057 ESEKQQALSLKESEKTALSEKL---MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL 1113
Query: 886 TRESDRLEEKGSLTEGALAHS 906
T E L + E A AH+
Sbjct: 1114 TSELRDL--RAQREEAAAAHA 1132
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 56.2 bits (134), Expect = 2e-07
Identities = 147/710 (20%), Positives = 260/710 (36%), Gaps = 125/710 (17%)
Query: 339 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKK-EEERKKMEKLLA 397
V R +E+ + QL + W + R + ++ K+ EE+R+K E+ A
Sbjct: 63 VDDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRA 122
Query: 398 G-EDGTSERRKSIKTYREIV----QEKERRERELHEAYKNARSQEEAEGILQQYIERFTI 452
E+ +R + K E V E+ ++ ++ H + S + I +R ++
Sbjct: 123 AVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGSPSIHSADPDRRSV 182
Query: 453 SEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASV 512
S L + P I +R S+ L LN P+ + L+ L P + + S
Sbjct: 183 STMNLSKYVDPVISKRLSSSSATL---LNSPDRARRLQ---LSPWESSVVNRLLTPTHSF 236
Query: 513 LDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHR--- 569
L S S + S P++ P + +NS D K F + S +H
Sbjct: 237 LARSKSTAALSGEAA---SCSPIIMPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTAS 293
Query: 570 -EEEKERE-------------CPTVAPAHSLTKSQMF---EGVARVHGSPLELKQ-DNGS 611
++E+ERE P+ A +S+++ + + + G+P GS
Sbjct: 294 YKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGS 353
Query: 612 IEI---NIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFT 663
++ ++ P+ V +E+ EK +P + K S KG L E
Sbjct: 354 VKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEE---- 409
Query: 664 TTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEA 723
TV EE+ +PE + P S A
Sbjct: 410 ATV-----------------------EERTPAEPEVGPAAPAMAPAPASAPAPASAPAPA 446
Query: 724 TLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEE------ERRRQE 777
+ P + P +S V++ +S K+ T DPEE E+RR
Sbjct: 447 PVPTPAMVSAP----------SSTVNASASVKTSAGTT------DPEEATRLLAEKRRLA 490
Query: 778 KWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI-IEDTVVPFTVSSS 836
+ Q+E+E + R Q+E ++ K E E AQ+ EE R EE R++ E
Sbjct: 491 REQREKEER-ERREQEELERQKRE-ELAQRVAEERTTRREEESRRLEAEQAREKEEQLQR 548
Query: 837 SADQLSTSSSMTEGSGTMNKIDLGNCQDE----KQDRRWKKSFQGDDSDLLLKTRESDRL 892
A++ + K + ++E +Q+R +K FQ ++ + L + + + +
Sbjct: 549 QAEERALREREEAERAQRQKEEEARVREEAERVRQER--EKHFQREEQERLERKKRLEEI 606
Query: 893 EEKGSLTEGALAHSGN----PVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNP 948
++ TE + + ++KG TE A C TN P + +P
Sbjct: 607 MKRTRRTEATDKKTSDQRNGDIAKGALTG---GTEVSALPCTTNA-----PGNGKPVGSP 658
Query: 949 ----THSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 994
+H S+ T L+K P+E S+ + LP+G
Sbjct: 659 HVVTSHQSKVTVESTPDLEK-------QPNENGVSVQNENFEEIINLPIG 701
Score = 34.3 bits (77), Expect = 0.64
Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 5/106 (4%)
Query: 335 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 394
+ A + +R +E +L Q RE++++ Q R R ++ +R+K E+
Sbjct: 517 QRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAE-----RAQRQKEEE 571
Query: 395 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 440
E+ R++ K ++ QE+ R++ L E K R E +
Sbjct: 572 ARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATD 617
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 54.7 bits (130), Expect = 5e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 876 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 930
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Query: 931 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 989
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
Query: 990 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1046
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 54.7 bits (130), Expect = 5e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 876 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 930
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Query: 931 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 989
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
Query: 990 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1046
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 54.7 bits (130), Expect = 5e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 876 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 930
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Query: 931 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 989
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
Query: 990 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1046
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 53.5 bits (127), Expect = 1e-06
Identities = 122/602 (20%), Positives = 235/602 (39%), Gaps = 105/602 (17%)
Query: 344 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTS 403
+ R +L Q +E ++++A ++ + +S S +L ++ +E+ L+ D
Sbjct: 293 KCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLS--DIEE 350
Query: 404 ERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAV-LERLEM 462
+ +Y++ +Q+ E R ++ E L++Y + + A+ +E
Sbjct: 351 RHNHDLSSYQDTIQQLENELRG---------TKWEMARHLREYQDLLNVKMALDIEIAAY 401
Query: 463 PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSG 522
K+LE E S+F Y + PP T+ + I + V
Sbjct: 402 RKLLE---GEETRFSTFAGSITGPLYTHR----PP---ITISSKIQKPKV---------E 442
Query: 523 SPSKTVTPKAVPMLTPKPYSQPKNSQ--DVLKTFKVDGKVSVNGETVHREEEKERECPTV 580
+P V K V + + + + S+ + L + VS+ E EEKE E
Sbjct: 443 APKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAE 502
Query: 581 APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQED 640
+ KS V + E+K++ G E + ++ A +++ E
Sbjct: 503 EEEVAAKKSP-------VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE------ 549
Query: 641 KNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPEN- 699
+GG ++G+ E E + E + + + + +E K++KK E
Sbjct: 550 --EGGSEKEGSSEKEEGEQE----------------EGETEAEAEGEEAEAKEEKKVEEK 591
Query: 700 --EMSGKVELVLSQKVVKP---KSPEPEATLTFPF---LDKMPEANQLHLPNLNSQVD-- 749
E++ K ELV KV KP KSP P++ + + K P + P S V+
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 750 -------SPSSE--KSPV-MTPFKFWAWDP------EEERRRQE--KWQQEQERLLQERY 791
SP E KSPV +P + A P EE + + E K +Q++E + +
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711
Query: 792 QKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV-------SSSSADQLSTS 844
+++K++++ EK + E+++ +E + E + +V + L
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 845 SSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG-----DDSDLLLKTRESDRLEEKGSLT 899
+ G + G+ + K R+ + G ++ + K + S R EEKG +T
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 900 EG 901
G
Sbjct: 832 NG 833
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 42/362 (11%)
Query: 319 VSDDAESTSMFDMRCEEEAAVQPHSR----ARQEQLQLINNQLREEDDKWQDDLARWKSR 374
V + E T + D + E E A+ + + +E+ + + EE + ++++A KS
Sbjct: 453 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 512
Query: 375 RRS----VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 430
++ V ++ +KEEE + E+ E S++ + + +E EKE E+E E
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
Query: 431 KNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTE-PNLSSFLND------- 482
A EEAE ++ +E + A E L +E+ + P S + +
Sbjct: 573 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 483 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYS 542
+P++ + +P ++ + ++ V + S S SP V KA + P
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP---VEEKAKSPVPKSPVE 688
Query: 543 QPKNSQDVLK-----TFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR 597
+ K+ +V K + + K + E V ++EEK ++ P A S K + V
Sbjct: 689 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 748
Query: 598 VHGSPLELKQDNGSIEINIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGK--SRKG 650
+ S++++++K + QE E S+E+ +D G SRK
Sbjct: 749 I----------TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 798
Query: 651 NI 652
+I
Sbjct: 799 DI 800
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 53.5 bits (127), Expect = 1e-06
Identities = 83/427 (19%), Positives = 170/427 (39%), Gaps = 62/427 (14%)
Query: 570 EEEKERECPTVAPAH-SLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAA 628
E +KE + PT+ A SL +M A + E K ++ I++ +V +
Sbjct: 116 ERQKEFD-PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 629 TTEK-TEPNSQEDKN----DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ 683
+ E N +EDK + K ++G+I E T TV
Sbjct: 175 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVM-------S 227
Query: 684 LKNDVSEEKDQKKPENEMSGKVELVLSQKVV---KPKSPEPEATLTFPFLDKMPEANQLH 740
LKN ++ K+ E G E+ +K+ K ++ A L +++
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKK 287
Query: 741 LPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKE 800
+ + +++++ EK+ +ER R+E ++E+ R ++R +E+ ++KE
Sbjct: 288 IADERARIEA--EEKAAA------------QERERREAEERERMREEEKRAAEERQRIKE 333
Query: 801 EWEKAQKE---VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKI 857
E ++A +E ++EEE+R EE ++I E+ +A++ + + E + +
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEE-------EKRAAEERQRARAEEEEKAKVEEQ 386
Query: 858 DLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHED 917
+EK+ + +G+ ++E+K G V++ ++
Sbjct: 387 KRNKQLEEKKHAMQETKIKGE------------KVEQK---------IEGKWVNEKKAQE 425
Query: 918 HQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERR 977
+L T Q + Q PT E++K + + DK +++S +R+
Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 485
Query: 978 KSISGKK 984
K + K
Sbjct: 486 KGFTEVK 492
Score = 51.2 bits (121), Expect = 5e-06
Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 45/280 (16%)
Query: 570 EEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAAT 629
EEE RE A L + Q E + +V +E+N + NSVP E A T
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQV----------TDQVEVNAQ--NSVPDEEAKT 81
Query: 630 TEKTEPNSQEDKNDGG----------KSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFP 679
T N+Q + +D + R+ ++ A + F T+T S ++
Sbjct: 82 TTT---NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLP----- 133
Query: 680 SSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFL---DKMPEA 736
S +++ND +E + +K E S + + + KS + DK E
Sbjct: 134 -SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 192
Query: 737 NQLHLPNLNS----QVD------SPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERL 786
+ P S QV+ + S++ V+ K EE ++ +E+ +Q + +
Sbjct: 193 EEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER-EQGSDEI 251
Query: 787 LQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 826
+E+DK + E E+A+ E EE ER E+++KI ++
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Score = 47.4 bits (111), Expect = 7e-05
Identities = 109/573 (19%), Positives = 214/573 (37%), Gaps = 88/573 (15%)
Query: 334 EEEAAVQPHSRARQEQLQ-------------------------------LINNQLREEDD 362
EEEAA + RARQE+L+ N Q+ +D+
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 93
Query: 363 K-WQDDLARWKSRRRSVSQDLIKKEEE-------------RKKMEKLLAGEDGTSERRKS 408
+ + LAR + RR+ Q+ +++++E ++M+ A + T + KS
Sbjct: 94 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153
Query: 409 -IKTYREIVQEKER-----RERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 462
+ R ++E E ++ + +A +N + +E E ++ +R +I E +E +
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE 213
Query: 463 PKILERSHSTE----PNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMS 518
K E T N +P + Q S E RA +
Sbjct: 214 EKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 519 AGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECP 578
A K K + + ++ K + + + + + + E EE++R
Sbjct: 274 AEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKE 333
Query: 579 TVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQ 638
A + ++ E R +K++ ++ + +E A E+
Sbjct: 334 EEKRAAE-ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392
Query: 639 EDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT-VAFVEFPSSPQLKNDVSEEKDQKKP 697
E+K + K E + + + + + K + K +K
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ 452
Query: 698 ENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMP-------------------EANQ 738
E++ + K E + +K+ K K P+ E F+D+ N
Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVK---SFMDRKKGFTEVKSQNGEFMTHKLKHTENT 509
Query: 739 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQK---EQ 795
P + VD+ +E +P + K EE RRR+ + + E+ L+++ Q+ E
Sbjct: 510 FSRPGGRASVDTKEAEGAPQVEAGKRL----EELRRRRGETESEEFEKLKQKQQEAALEL 565
Query: 796 DKLKEEWEKAQKEVEEEERRYYEEE--RKIIED 826
++LK++ E+ +K +EEEE+R +EE RK+ E+
Sbjct: 566 EELKKKREERRKVLEEEEQRRKQEEADRKLREE 598
Score = 46.6 bits (109), Expect = 1e-04
Identities = 122/612 (19%), Positives = 232/612 (37%), Gaps = 128/612 (20%)
Query: 231 SDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRK---- 286
+D+ LP R++ ++D + T+ E KS +Y + +T V +K
Sbjct: 126 TDASLSLPSRRM----QNDTAENETTEKEEKSESRQERY---EIEETETVTKSYQKNDWR 178
Query: 287 -----KKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
KK ++E+ + GE ++ E T + ++ + ++ +P
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 342 HSRARQEQL--QLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGE 399
+EQ ++ +++ EE+DK + + R +R + ++ IK E+++K +
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAER--ARLEAEERERIKAEQDKKIAD------ 290
Query: 400 DGTSERRKSIKTYREIVQEKERRERELHEAYKNA--RSQEEAEGILQQYIERFTISEAVL 457
ER + + QE+ERRE E E + R+ EE + I ++ A
Sbjct: 291 ----ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE------KRAAE 340
Query: 458 ERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSM 517
ER + + E + E +Q + + A E ARA
Sbjct: 341 ERQRIKE--EEKRAAE----------------ERQRIKEEEKRAAEERQRARAE------ 376
Query: 518 SAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKEREC 577
+K K L K ++ + +K KV+ K+ G+ V+ ++ +E +
Sbjct: 377 ---EEEKAKVEEQKRNKQLEEKKHAMQETK---IKGEKVEQKIE--GKWVNEKKAQEDKL 428
Query: 578 PTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNS 637
T ++ K Q E +V +L++D KP +E+ K +
Sbjct: 429 QT-----AVLKKQGEEKGTKVQAKREKLQED---------KPTFKKEEIKDEKIKKDKEP 474
Query: 638 QEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKP 697
+E+ +KG E+ S + T + T S P + V ++ + P
Sbjct: 475 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTF------SRPGGRASVDTKEAEGAP 528
Query: 698 ENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSP 757
+ E ++E ++ + E E+ K EA
Sbjct: 529 QVEAGKRLE------ELRRRRGETESEEFEKLKQKQQEA--------------------- 561
Query: 758 VMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQD-KLKEEWEKAQKEVEEEERR- 815
A + EE ++++E+ ++ E Q R Q+E D KL+EE EK + + E E RR
Sbjct: 562 --------ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 613
Query: 816 -YYEEERKIIED 826
E+ +K+ ED
Sbjct: 614 EAAEKRQKMPED 625
Score = 35.0 bits (79), Expect = 0.37
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 23/206 (11%)
Query: 768 DPEEERRRQEKWQQEQERLLQER--YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 825
D E RR + ++E+ RL ER YQ+ D +E + ++ +E R +EE + +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 826 DT-VVPFTVSSSSADQ---LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD--- 878
T V +S D+ +T+++ EG ++ ++E++ +R +++ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 879 -----DSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQL-DTEAGAPHCGTN 932
D+ L L +R + TE S+ E +++ +TE N
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTE------KEEKSESRQERYEIEETETVTKSYQKN 175
Query: 933 PQLAQDPSQNQQTSNPTHSSEDVKPK 958
+D +N++ E+ KPK
Sbjct: 176 DW--RDAEENKKEDKEKEEEEEEKPK 199
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 52.8 bits (125), Expect = 2e-06
Identities = 101/480 (21%), Positives = 181/480 (37%), Gaps = 74/480 (15%)
Query: 385 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERR-----ERELHEAYKNARSQEEA 439
K +ER+++ K + ER K + + + EK++R E+++ E ++ Q +
Sbjct: 50 KSDERQRLAK-----ERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQR 104
Query: 440 EGILQQYIE--RFTISEAVLERLE--MPKILERSHSTEPNLSSFLNDP---NPMKYLRQQ 492
E + +E R ERLE M + LER+ E P P +
Sbjct: 105 EDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACD 164
Query: 493 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKT--VTPKAVPM--LTPKPYSQPKNSQ 548
L + T L +S A S SP + V P+ P+ L P S P +
Sbjct: 165 KLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNI 224
Query: 549 DVLKTFKVD-------GKVSVNG------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 595
+ K GK +++G E V R + P V L + + G+
Sbjct: 225 EKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGI 284
Query: 596 ARVHGSPLELKQDNGSIEINIK--KP----NSVPQELAATTEKTEPNSQEDKNDGGKSRK 649
+ SP+ K + + K KP + V L A + + P + +K K R+
Sbjct: 285 PKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKERE 344
Query: 650 GNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL 709
G + ++ PQ L+ V ++ +K GK E
Sbjct: 345 GTLAQQAAGPQ-------------------GEEALEKHVVDKHASEKHAAAAGGKAEN-- 383
Query: 710 SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP 769
S + KP + +A L + + Q L + + E+ D
Sbjct: 384 SAALGKPTAGTTDAGEAAKILAE--KRRQARLQKEQEEQERVEKEEQ-----------DR 430
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVV 829
E + K ++E+ RL +E ++E+++ ++E EK ++E EE+ + E +RK E+ ++
Sbjct: 431 LEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLL 490
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/314 (21%), Positives = 127/314 (40%), Gaps = 41/314 (13%)
Query: 211 RSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYL 270
R ++T + V+ S R + +P R P +A + PK+ P
Sbjct: 258 RGQRTATSLPVVNFGSPLRRCEFSGGIPKR--PSSPVISKTATKAYPQSPKTTKPPYPGS 315
Query: 271 PNKSNQTAYVPAPLRKKKAEREEYRKSWS-----TATSPLGGERPFRYGPRTPVSDD--- 322
P K A + K+KAE+E+ K A P G E ++ S+
Sbjct: 316 PVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAA 375
Query: 323 -----AESTSMFDMRCEE-----EAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWK 372
AE+++ EAA + RQ +LQ + + + QD L R +
Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435
Query: 373 SRRRS------VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE---KERRE 423
+R++ + ++ K+EEERK+ E+ ++G +R+ + R+ +E KE++E
Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQE 495
Query: 424 RELHEAYKNARSQEEAEGILQQYIERFTIS-EAVLERLEMPKILERSHSTEPNLSSFLND 482
+E E + +E AE ++ E+ + E ++ ++E ++ + E
Sbjct: 496 QEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDE--------- 546
Query: 483 PNPMKYLRQQSLPP 496
MK R+ +PP
Sbjct: 547 --IMKRTRKSDVPP 558
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 51.6 bits (122), Expect = 4e-06
Identities = 98/511 (19%), Positives = 196/511 (38%), Gaps = 70/511 (13%)
Query: 332 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 387
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 388 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGIL 443
E ++ +KL E+ E+ + + E ++E+E R+E L E K R QE + +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE--QKMR 355
Query: 444 QQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATV 503
Q + E + E+ E + E+ E + K +R++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE---------- 405
Query: 504 ETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVN 563
ET + + K + +P K + Q K + K ++ + K+
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 564 GETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKK 618
E +E +EK RE + QM+E ++ ++ +
Sbjct: 466 EEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERM------ 509
Query: 619 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEF 678
E + E +E K + K E + E + T +
Sbjct: 510 -----WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW------------DQ 552
Query: 679 PSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQ 738
+ + + E + + + E EM + E + ++ K + E + + +KM E +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM---WEQEEKMQEQEE 609
Query: 739 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQD 796
+ +K M + W+ EE+ + QE+ W+QE++ QE +EQ+
Sbjct: 610 KMWEQEEKMWEQEEEDK---MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 797 KLKEEWEKAQKEVEE----EERRYYEEERKI 823
+ + E+ +E EE +E + E+E K+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Score = 51.6 bits (122), Expect = 4e-06
Identities = 98/510 (19%), Positives = 201/510 (39%), Gaps = 75/510 (14%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 390
+R +EE + R R+++ ++RE+++K + R + R R ++L ++E+E +
Sbjct: 250 IRKQEEKMWRQEERLREQE-----GKMREQEEK----MRRQEKRLREQEKELREQEKELR 300
Query: 391 KMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGILQQY 446
+ +KL E+ E+ + + E ++E+E R+E L E K R QE+ + Q
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK--MRDQE 358
Query: 447 IERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETT 506
+ E + E+ E + E+ E + K +R++ ET
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE----------ETM 408
Query: 507 IARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGET 566
+ + K + +P K + Q K + K ++ + K+ E
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 567 VHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI---EINIKK 618
+E +EK RE + QM+E ++ ++ + + +++
Sbjct: 469 WGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 619 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFV-E 677
+E ++ E +E K + + + E E + + + E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 678 FPSSPQLKNDVSEEKDQK--KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPE 735
Q + + E+++K + E +M + E + Q+ + E DKM E
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE---------DKMQE 629
Query: 736 ANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQ 795
++ E+ M + W+ EE+ R QE+ +EQE E+ Q ++
Sbjct: 630 QEEM------------MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE----EKMQGQE 673
Query: 796 DKLKEEWEKAQ----KEVEEEERRYYEEER 821
+K++E+ EK Q K E+EE+ +EE+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 47.4 bits (111), Expect = 7e-05
Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 18/141 (12%)
Query: 767 WDPEEERRRQEK--WQQE-----QERLLQERYQKEQDKLKEEWEKAQKEVEEEER----- 814
W+ EE+ R QE+ W+QE QE+ ++E+ QK +D+ + WE+ ++ E+EER
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 815 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 874
+ +E+E K+ E+ + +M E M K + E++++ W++
Sbjct: 380 KMWEQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQ 433
Query: 875 FQGDDSDLLLKTRESDRLEEK 895
+ + L + + EEK
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEK 454
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 14/132 (10%)
Query: 767 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKA---QKEVEEEERRYYEEERKI 823
W+ +E R +E+ +EQ+++ Q+ + ++K +E EK Q+E EE R E E+K+
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 824 IEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLL 883
E+ + +Q M E M + Q+EK + +K ++ ++ +
Sbjct: 570 REEEEMMREQEEKMQEQ---EEKMREQEEKMWE------QEEKMQEQEEKMWEQEEK--M 618
Query: 884 LKTRESDRLEEK 895
+ E D+++E+
Sbjct: 619 WEQEEEDKMQEQ 630
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 699 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQV--------DS 750
NE K L +K+ +S + E L L + E + LP + + +
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 751 PSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLL--QERYQKEQDKLKEEWEK---A 805
E+ + + W EE R QE +EQE + QE+ +EQ+K E EK
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 806 QKEVEEEERRYYEEERKIIE 825
QK++ E+E + E+E K+ E
Sbjct: 302 QKKLREQEEQMQEQEEKMWE 321
Score = 39.7 bits (91), Expect = 0.015
Identities = 24/71 (33%), Positives = 44/71 (61%), Gaps = 11/71 (15%)
Query: 767 WDPEEERRRQEK--WQQEQ------ERLLQ-ERYQKEQDKL--KEEWEKAQKEVEEEERR 815
W+ EE+ R QE+ W QE+ ERL + E +EQ K+ +EE + +K+ +E+E++
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 816 YYEEERKIIED 826
+++E K+ E+
Sbjct: 549 TWDQEEKMREE 559
Score = 38.9 bits (89), Expect = 0.026
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 11/129 (8%)
Query: 768 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIED 826
+ EE R QE+ QEQE ++E+ +K ++ ++ E+ +K E+EE+ + EEE K+ E
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 827 TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT 886
+ + +Q M E M + Q+EK R ++ QG + + +
Sbjct: 631 EEMMWEQEEKMQEQ---EEKMWEQEEKMRE------QEEKM-REQEEKMQGQEEKMREQE 680
Query: 887 RESDRLEEK 895
+ EEK
Sbjct: 681 EKMQGQEEK 689
Score = 37.7 bits (86), Expect = 0.058
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 19/142 (13%)
Query: 690 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 749
EEK QK+ EN + + Q++ + K E +K+ E + + Q +
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE----KIRDQEE 467
Query: 750 SPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEV 809
EK K W +E+ R QE EQE ++++ QK D+ + WE+ ++
Sbjct: 468 MWGQEK-------KMWR---QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 810 EEEER-----RYYEEERKIIED 826
E+EER + +++E K+ E+
Sbjct: 518 EKEERMREQKKMWQQEEKMREE 539
Score = 37.0 bits (84), Expect = 0.098
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 26/143 (18%)
Query: 770 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE-----------EERRYY 817
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE ++ E+ +
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 818 EEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 877
E+E KI E Q E G K+ E++D+ W++ +
Sbjct: 450 EQEEKIWE--------------QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 878 DDSDLLLKTRESDRLEEKGSLTE 900
D + + +E E+ L E
Sbjct: 496 RDQEQKMWDQEERMWEQDERLRE 518
Score = 36.2 bits (82), Expect = 0.17
Identities = 57/275 (20%), Positives = 113/275 (41%), Gaps = 39/275 (14%)
Query: 284 LRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS 343
+R++K +E+ +K+W ER + ++ M+ +EE +
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 344 RA--RQEQLQLINNQL---------REEDDKWQD-DLARWKSRRRSVSQD--------LI 383
+ ++E++Q ++ +EE+DK Q+ + W+ + Q+ +
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655
Query: 384 KKEEE--RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 441
+++EE R++ EK+ E+ E+ + ++ QE++ RE+E + R QEE
Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQG-----QEEKMREQE-----EKMRGQEEK-- 703
Query: 442 ILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTA 501
+ Q + + E + + EM + ER + + L P + + LPP K
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL--PEHEERCSEPCLPPSKVLC 761
Query: 502 TVETTIARASVLDTSMSAGSGSPSKTVTPKAVPML 536
+ T SV AG GSP T + + L
Sbjct: 762 NMSHT---GSVEPAGGEAGEGSPQDNPTAQEIMQL 793
Score = 35.8 bits (81), Expect = 0.22
Identities = 31/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 690 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 749
EE+D+ + + EM + E + ++ K E + + + E Q + Q +
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 750 SPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQDKLKEEWEKAQK 807
++ + + EE+ R QE+ W QE++ QE Q++++E+ E+ +
Sbjct: 682 KMQGQEEKMR--------EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Query: 808 EVEEEERRYYEEERKIIEDTVVPFTV 833
+ E+ + R E E + E + P V
Sbjct: 734 QKEKMQERLPEHEERCSEPCLPPSKV 759
Score = 34.3 bits (77), Expect = 0.64
Identities = 17/59 (28%), Positives = 35/59 (59%)
Query: 768 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 826
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Score = 31.6 bits (70), Expect = 4.1
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 9/107 (8%)
Query: 340 QPHSRARQEQLQLINNQLREEDDKWQDDLAR-WKSRRRSVSQDLIKKEEERKKM----EK 394
Q + QE++ +LRE++ K + + W+ R Q+ K E+ +KM ++
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG-KMREQEEKMRRQEKR 284
Query: 395 LLAGEDGTSERRKSI---KTYREIVQEKERRERELHEAYKNARSQEE 438
L E E+ K + K RE ++ + +E ++ E + R QEE
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Score = 30.8 bits (68), Expect = 7.0
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 23/138 (16%)
Query: 347 QEQLQLINN-----QLREEDDKWQDDLARW---KSRRRSVSQDLIKKEEE--------RK 390
QE+L+L + QL ++ K + + A++ + + ++ +++ ++EEE RK
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 252
Query: 391 KMEKLLAGEDGTSERRKSIKTYREIVQEKERR----ERELHEAYKNARSQE---EAEGIL 443
+ EK+ E+ E+ ++ E ++ +E+R E+EL E K R Q+ E E +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 444 QQYIERFTISEAVLERLE 461
Q+ E+ E + E
Sbjct: 313 QEQEEKMWEQEEKMREQE 330
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 772 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 147 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 204
Query: 832 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 890
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 205 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 258
Query: 891 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 947
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318
Query: 948 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 983
S+E+V + + D ++ NH + P R SG+
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Score = 39.3 bits (90), Expect = 0.020
Identities = 19/59 (32%), Positives = 37/59 (62%), Gaps = 6/59 (10%)
Query: 771 EERRRQEKWQ----QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 825
++ +R+EKW+ +E+E ++R+++EQDK + EWE+ ++ E R + ER +E
Sbjct: 101 KDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRR--EMAREHSRRERDRLE 157
Score = 38.9 bits (89), Expect = 0.026
Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 18/122 (14%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSR------RRSV 378
SM D E++ A P +R+E++ ++ R+E KW+ AR K R R
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE--KWKH--ARVKEREHERRKRHRE 127
Query: 379 SQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEE 438
QD ++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E
Sbjct: 128 EQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKE 181
Query: 439 AE 440
E
Sbjct: 182 RE 183
Score = 31.6 bits (70), Expect = 4.1
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 359 EEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE 418
EEDD + SR+ V +K+E+RK+ K ++ ERR K +RE Q+
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHH---RKDEKRKEKWKHARVKEREHERR---KRHRE-EQD 130
Query: 419 KERRERELHEAYKNARSQEEAEGILQQYIER 449
K RRE E + + AR E + +ER
Sbjct: 131 KARREWERQKRREMAREHSRRERDRLEQLER 161
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 772 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 157 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 214
Query: 832 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 890
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 268
Query: 891 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 947
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 948 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 983
S+E+V + + D ++ NH + P R SG+
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Score = 33.9 bits (76), Expect = 0.83
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 431
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 131 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 184
Query: 432 NARSQEEAE 440
R Q+E E
Sbjct: 185 EQREQKERE 193
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 772 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 148 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 205
Query: 832 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 890
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 259
Query: 891 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 947
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319
Query: 948 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 983
S+E+V + + D ++ NH + P R SG+
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Score = 35.4 bits (80), Expect = 0.29
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRRRSVSQD 381
SM D E++ A P +R+E++ ++ R+E + + + +R QD
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
Query: 382 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 440
++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E E
Sbjct: 132 KARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKERE 184
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 772 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 125 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 182
Query: 832 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 890
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 183 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 236
Query: 891 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 947
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296
Query: 948 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 983
S+E+V + + D ++ NH + P R SG+
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 336
Score = 33.9 bits (76), Expect = 0.83
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 431
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 99 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 152
Query: 432 NARSQEEAE 440
R Q+E E
Sbjct: 153 EQREQKERE 161
Score = 30.8 bits (68), Expect = 7.0
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIK 384
SM D E++ A P +R+E++ ++ R+E + + A R ++
Sbjct: 38 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE--- 94
Query: 385 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+E ER+K + E + R + RE+ +E RRER+ E + R +E
Sbjct: 95 REHERRKRHR---EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 144
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 772 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 114 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 171
Query: 832 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 890
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 225
Query: 891 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 947
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 226 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 285
Query: 948 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 983
S+E+V + + D ++ NH + P R SG+
Sbjct: 286 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 325
Score = 35.4 bits (80), Expect = 0.29
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRRRSVSQD 381
SM D E++ A P +R+E++ ++ R+E + + + +R QD
Sbjct: 38 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 97
Query: 382 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 440
++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E E
Sbjct: 98 KARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKERE 150
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 772 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 159 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 216
Query: 832 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 890
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 217 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 270
Query: 891 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 947
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 330
Query: 948 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 983
S+E+V + + D ++ NH + P R SG+
Sbjct: 331 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Score = 33.9 bits (76), Expect = 0.83
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 431
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 133 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 186
Query: 432 NARSQEEAE 440
R Q+E E
Sbjct: 187 EQREQKERE 195
Score = 30.8 bits (68), Expect = 7.0
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIK 384
SM D E++ A P +R+E++ ++ R+E + + A R ++
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE--- 128
Query: 385 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+E ER+K + E + R + RE+ +E RRER+ E + R +E
Sbjct: 129 REHERRKRHR---EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 178
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 48.9 bits (115), Expect = 2e-05
Identities = 121/633 (19%), Positives = 251/633 (39%), Gaps = 64/633 (10%)
Query: 259 EPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTP 318
E + + +P + + L +KK + + R+ W + L + Y +
Sbjct: 1780 EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNL 1839
Query: 319 VSDDAESTSMFDMRCE-EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRS 377
+ + + +E + R + QL+ Q++ + + LA+ + +
Sbjct: 1840 AQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLV--QVKNKLGMFNKILAQVEEKLTQ 1897
Query: 378 VSQDLIKKEEERKKMEK-LLAGEDGTSERRKSIKTYR-------EIVQEKERRERELHEA 429
+ +IKK+E+ + EK L+ ED +++++ + + +VQ K+R EL A
Sbjct: 1898 EKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957
Query: 430 YKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYL 489
+ E + + ++ + R + L + E P+ + T+ F +
Sbjct: 1958 KEEKALNLEMKRLAEEKM-RLVEGKETLSKGETPETSRQRKMTQVEQELF---ERKLSLE 2013
Query: 490 RQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQD 549
+ L + A E+ IA+ L+ + + KA L K S K
Sbjct: 2014 EKILLHEDRILAMEESEIAKGK-LEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAK 2072
Query: 550 VLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR--VHGSPLELKQ 607
+ K K K++ + + +EE K + K +F R + S L++K+
Sbjct: 2073 LNKILKALQKLTRDERKLTQEEIKMTKM----------KRALFVKERRLSIEQSKLDIKE 2122
Query: 608 DNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVT 667
+ S +K + + ++ K + + + K K E + +H + +
Sbjct: 2123 WDFS-----EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKH-SEVIL 2176
Query: 668 RCSPTVAFVEFPSSPQLKNDVSEEKDQK---KPENEMSGKVELVLSQKVVKPKSPEPEAT 724
E P LK + K+ K KP+ + S +V+ V S++ S E E+
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF---SEEMES- 2232
Query: 725 LTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQE 784
LD++ + L + + E+ V + EEER+ +E+ +++Q
Sbjct: 2233 ----LLDELEKQESLSSEEEEEREEEEEREEEEVR--------EEEEERKEEEEGEEKQV 2280
Query: 785 RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTS 844
++E++K K++ EK ++EV+E+E + E+E + E+ T S S ++ S
Sbjct: 2281 E------KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE----TESLSDEEEEEES 2330
Query: 845 SSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 877
S+ E +I Q + Q++R +KS +G
Sbjct: 2331 CSLEEEVDREKEILKKEKQFKLQEQR-RKSLRG 2362
Score = 38.5 bits (88), Expect = 0.034
Identities = 20/60 (33%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEE---WEKAQKEVEEEERRYYEEERKIIED 826
E+++ + E+W+Q E +L + +++Q K +EE E+ +E EE+E++ EE+R I E+
Sbjct: 1512 EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Score = 36.6 bits (83), Expect = 0.13
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 20/147 (13%)
Query: 688 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLP----- 742
V+ E+++ + +V+ +L+QKV + P+ E L + + E +L
Sbjct: 1672 VAREEEKLAKKGGKLAEVKNILAQKV--EELPQREQNLDWQEKELAQELEELEWDMEELS 1729
Query: 743 ----NLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKL 798
LN + EK + + AW E+ + K QE+E L+QE
Sbjct: 1730 WKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQE--------- 1780
Query: 799 KEEWEKAQKEVEEEERRYYEEERKIIE 825
KE+ + ++++ EEE R + ++IE
Sbjct: 1781 KEKLAQHKEKMPEEEERLGRKREQLIE 1807
Score = 36.6 bits (83), Expect = 0.13
Identities = 16/60 (26%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
Query: 767 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 826
WD EE ++E+ QE+ +L++E+ + +++ W++ +++ EEE + +EE +I++
Sbjct: 1723 WDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQR--EKLSEEETKLAQEEELLIQE 1780
Score = 35.8 bits (81), Expect = 0.22
Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 23/175 (13%)
Query: 744 LNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWE 803
L +V EK +T EE+R QE + + R+ ++R + E+ + +EE +
Sbjct: 1546 LEEEVSREGEEKEQQVT---------EEQRHIQE--EHKWARIHRKRARAEKKRAQEERK 1594
Query: 804 KAQKE--VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGN 861
AQ+E + +EER+ +EERK+ + V ++ + + T+ +
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYV---KITQDDREMAQAEGKFAQKEETLAQ----- 1646
Query: 862 CQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHE 916
+ EK + +K Q L K + R EEK + G LA N +++ V E
Sbjct: 1647 -RGEKLSQEAEKLAQ-KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEE 1699
Score = 34.3 bits (77), Expect = 0.64
Identities = 122/700 (17%), Positives = 261/700 (37%), Gaps = 85/700 (12%)
Query: 346 RQEQLQLINNQLREEDDKW--QDDLARWKSRRRSVSQDLIKKEEER--KKMEKLLAGEDG 401
++E+L +L EE K +++ W+ + S + + +EEE ++ EKL ++
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
E + + RE + EK+ + + E + N+ +E + + Y ++ E E
Sbjct: 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSM-EELTKNKMILYQKKNLAQEKKNLAQE 1849
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
K+ +R + N + + ++ + K A VE + +
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
K + + + + + L+ V GK + GE +EEK
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEK-------- 1961
Query: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNS--QE 639
A +L ++ E R+ L + +K V QEL E E
Sbjct: 1962 -ALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHE 2020
Query: 640 DK---NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKK 696
D+ + + KG +E + FV+ Q K + K KK
Sbjct: 2021 DRILAMEESEIAKGKLEFTRGQR--------------IFVQ----GQRKLAKASRKLIKK 2062
Query: 697 PEN--EMSGKVELVLS--QKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPS 752
E+ + K+ +L QK+ + + + + + + + L S++D
Sbjct: 2063 RESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Query: 753 ---SEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEV 809
SEK +T D ++ R+Q K + R++ + + +++ K + ++ +
Sbjct: 2123 WDFSEKRSELTK------DEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVIL 2176
Query: 810 EEEERRYYEEE------------RKIIEDTVVPFTVSSSSADQLSTSSSMTEG-SGTMNK 856
++EE EEE RK + P SS D++ + +E +++
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 857 IDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHE 916
++ +++ ++ + ++ + ++ E +R EE+ EG V K E
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEE--VREEEEERKEEE----EG----EEKQVEKEEEE 2286
Query: 917 DHQLDTEAGAPHCGTNPQLAQDPSQ-NQQTSNPTHSSEDVKPKTLPLDKSINH------- 968
+ E ++ ++ + + + S E+ + ++ L++ ++
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKK 2346
Query: 969 --QIESPSERRKSISGKKLCSSC--GLPLGKGAAMIIETL 1004
Q + +RRKS+ G++ S G+P GKG A+ + L
Sbjct: 2347 EKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVL 2386
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 11/76 (14%)
Query: 763 KFW-AWDPEEERR---RQEKWQQEQERLLQERYQKEQDKL------KEEWEKAQKEVEEE 812
K W AW E E+R +EK Q E+L E ++DK K+ WE + +
Sbjct: 1476 KSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSS-KSK 1534
Query: 813 ERRYYEEERKIIEDTV 828
E++Y +EE +E+ V
Sbjct: 1535 EQQYKDEEEVTLEEEV 1550
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.5 bits (114), Expect = 3e-05
Identities = 128/637 (20%), Positives = 225/637 (35%), Gaps = 109/637 (17%)
Query: 288 KAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQ 347
K E EE R+ L E+ R R ++ E R E ++ R+
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEER---LQQRLRSEQQLRREQEERR 546
Query: 348 EQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK----------KMEKLLA 397
EQL + R E ++ + L R + RR L+K+EEER+ ++E+ L
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERRQQRLKREQEERLEQRLK 603
Query: 398 GEDGT---SERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 454
E+ E R+ + RE E+ERR++ L + R Q++ Q+ E+ E
Sbjct: 604 REEVERLEQEERREQRLKRE-EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 455 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 514
ERLE + L+R H E + R +S P AR S
Sbjct: 663 EEEERLE--QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS--- 717
Query: 515 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 574
K YS+P+ + + + + K R E E
Sbjct: 718 ------------------------KVYSRPRKQEGQRRRQEQEEK--------RRRRESE 745
Query: 575 RECPTVAPAHSLTKSQMFEGVAR--VHGSPLELKQDNGSIEINIKKPNSVPQELAATTEK 632
+ AH + Q E R E K + G ++ + P +E E+
Sbjct: 746 LQWQEEERAH---RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 633 TE-------PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLK 685
+ P +E + + R+ EL E + E +
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE----------------EQLQRRERA 846
Query: 686 NDVSEEKDQKKPENEMSGKVELVLSQK----VVKPKSPEPEATLTFPFLDKMPEANQLHL 741
+ EE+D + + E E QK + + + P L + Q L
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 742 PNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQE---RLLQERYQKEQDKL 798
++ EK + + + + ++ ++ ++E+E R +ER ++ KL
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 799 KEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKID 858
+++ E+ E E E+RR E E+K E+ + +QL + +
Sbjct: 967 QQKEEQLLGE-EPEKRRRQEREKKYREEEEL-----QQEEEQL-----------LREERE 1009
Query: 859 LGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 895
Q+ ++ R K Q ++ LL + RE RL+E+
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Score = 46.6 bits (109), Expect = 1e-04
Identities = 46/188 (24%), Positives = 77/188 (40%), Gaps = 33/188 (17%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS- 343
++++ +R ++ W G + R R P+ + E + R + E P
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQ--RLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 344 ---------RARQEQLQLINN-----------QLREEDDKWQDDLARWKSRRRSVSQDLI 383
R R+++LQ + QL+EE+D Q+D + RRRS Q
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED----QERRRSQEQRRD 871
Query: 384 KK-----EEERKKMEKLLAGEDGTSER-RKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+K EEERK+ L + E+ RK + +E +E +R ERE + R
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 438 EAEGILQQ 445
E E + Q+
Sbjct: 932 EEEQLQQE 939
Score = 44.7 bits (104), Expect = 5e-04
Identities = 33/127 (25%), Positives = 66/127 (51%), Gaps = 11/127 (8%)
Query: 330 DMRCEEEAAV--QPHSRARQEQLQLINNQLREEDDKWQDDLA-----RWKSRRRSVSQDL 382
+++ EEE + +P R RQE+ Q REE++ Q++ R K RR+ + +
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQER----ERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 383 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 442
++EE +++ E+LL E R++ + YRE + ++ E+ L E + R + E +
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 443 LQQYIER 449
++ ++R
Sbjct: 1201 EEEELQR 1207
Score = 42.4 bits (98), Expect = 0.002
Identities = 111/622 (17%), Positives = 234/622 (37%), Gaps = 58/622 (9%)
Query: 330 DMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER 389
D + EEE P R RQ++ + E+ + + + R+R ++L ++ +E
Sbjct: 126 DRQLEEE----PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR-DEELWRQRQEW 180
Query: 390 KKMEKLLAGEDGTSERRKSIKTY--REIVQEKERRERELHEAYKNARSQ------EEAEG 441
++ E+ A E E+ +S K + E E++ R REL E + R + E +
Sbjct: 181 QEREERRAEE----EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 442 ILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTA 501
+ Q+ E+ + R E K+ E + L + ++ L +Q L +
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ---EEEEQLRKLERQELRRERQEE 293
Query: 502 TVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLK--------T 553
+ R + + + + + + + Q + +
Sbjct: 294 EQQQQRLRR---EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 554 FKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIE 613
+ + + + + RE+E+ER + L + Q ++ ++ E
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410
Query: 614 INIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTV 673
+++ + +E ++ +E++++ ++ + E + + R T
Sbjct: 411 QQLRREQQLRRE-----QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 674 AFVEFPSSPQLKNDVSEEKDQK--KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLD 731
+ QLK D EE+ ++ K E E + + Q++ + + E L
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL------ 519
Query: 732 KMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQE----RLL 787
K E + L S+ ++ K E+ RR+++ ++EQE +LL
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 788 QERYQKEQDKLKEEWEK--AQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSS 845
+ ++ Q +LK E E+ Q+ EE R +EER+ E + QL S
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERR--EQRLKREEPEEERRQQLLKSE 637
Query: 846 SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAH 905
E + L Q E++++R K+ + + + LK RE + + L E
Sbjct: 638 EQEE----RRQQQLRREQQERREQRLKREEEEERLEQRLK-REHEEERREQELAEEEQEQ 692
Query: 906 SGNPVSKGVHE-DHQLDTEAGA 926
+ + + + QL++EA A
Sbjct: 693 ARERIKSRIPKWQWQLESEADA 714
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Query: 770 EEERRRQEKW----------QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEE 819
E E+RR+++W QQE+E+LL+E +K + + +E + ++E+++EE + E
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 820 ERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDD 879
ER+ + Q + E + Q+ ++ R ++ Q ++
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR------QERERQCREEEELQQEE 1120
Query: 880 SDLLLKTRESDRLEE 894
LL + RE R +E
Sbjct: 1121 EQLLREEREKRRRQE 1135
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 19/164 (11%)
Query: 285 RKKKAEREEYRKSWSTATS-------PLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEA 337
R+ + +EE K W + L E P R + ++R E +
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 338 AVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDL----IKKEEERKKME 393
Q R R+EQ QL Q EE+ + Q + R + RR ++ +++E+E ++ +
Sbjct: 293 EEQQQQRLRREQ-QLRRKQ--EEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 394 KLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+L ++ E R+ + RE QE+ERRE++L + R Q+
Sbjct: 350 QLRREQE---EERREQQLRRE--QEEERREQQLRREQQLRREQQ 388
Score = 40.8 bits (94), Expect = 0.007
Identities = 23/54 (42%), Positives = 37/54 (68%), Gaps = 4/54 (7%)
Query: 770 EEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEKAQKEVEEEERRYYEEER 821
EEE+ RQE Q++ R QERY+K E+++L+ E E+ Q +E +R++ EEE+
Sbjct: 1727 EEEQLRQETEQEQLRR--QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 40.0 bits (92), Expect = 0.012
Identities = 56/252 (22%), Positives = 107/252 (42%), Gaps = 22/252 (8%)
Query: 234 ESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREE 293
E L + ++++++ RR E + + L + Q R+++ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 294 YRKS--WSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQ 351
YRK L GE P + R + + +++ EEE ++ R+ Q
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEK---RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 352 LINNQLREEDDKWQDD---LARWKSRRRSVSQDL-IKKEEERKKMEKLLAGEDGTSERRK 407
Q R++D+ Q++ L + +RR ++ ++EEE ++ E+ L GE+ + RR+
Sbjct: 1017 --ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 408 SI-KTYREIVQEKERRERELHEAYKNARSQE-----EAEGILQQYIERFTISEAVLERLE 461
+ + YR+ + ++ E+ L E + R QE E LQQ E+ E R +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 462 MPKILERSHSTE 473
LER + E
Sbjct: 1135 E---LERQYREE 1143
Score = 39.3 bits (90), Expect = 0.020
Identities = 31/148 (20%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIEDTV 828
EEE+ RQE+ +Q+ +R +E+++L++E E+ Q ++ + +Y +EEE+ +E+
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 829 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 888
+ + E S + + Q+E+Q RR ++ + + + + +E
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKS---RREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 889 SDRLEEKGSLTEGALAHSGNPVSKGVHE 916
R + G + G + G H+
Sbjct: 1892 EQRHRQVGEIKSQEGKGHGRLLEPGTHQ 1919
Score = 38.9 bits (89), Expect = 0.026
Identities = 18/51 (35%), Positives = 33/51 (64%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 820
E + R +E+ QQE+E+LL+E +K + + E + ++EV++EE + EE
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Score = 38.5 bits (88), Expect = 0.034
Identities = 127/646 (19%), Positives = 237/646 (36%), Gaps = 96/646 (14%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLRE----EDDKWQDDLARW-----KSRRRSVSQDLIK 384
EEE Q + +E+ + Q RE +D K Q + + RRR + +
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 385 KEEERKKMEKLLAGEDGTSERRKSI-KTYR---EIVQEKE---RRERELHEAYKNARSQE 437
+EEE ++ E+ L E+ RR+ + YR E+ QE+E R ERE + R
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 438 EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQ----QS 493
E E + Q+ + R E+ + + + L + P K RQ Q
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE-EPEKRRRQERERQC 1110
Query: 494 LPPPKFTATVETTIA------RASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNS 547
+ E + R L+ + V + +L +P + +
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYRE-----EEEVQQEEEQLLREEP--EKRRR 1163
Query: 548 QDVLKTFKVDGKVSVNGETVHREE------EKERECPTVAPAHSLTKSQMFEGVARVHGS 601
Q++ + ++ + ++ E + REE E+ER+ + Q + R
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY----RDEDQ 1219
Query: 602 PLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQH 661
+LK + N + N V E + ED + + +++ E Q
Sbjct: 1220 RSDLKWQWEPEKENAVRDNKV---YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 662 FTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEP 721
R FP QL+ + E+K+ K+ + + + +L+ ++ K + E
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLERE--EQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 722 EATLTFPFLDKMPEANQL-----HLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQ 776
+ K E QL P + D E+ + E+ RRQ
Sbjct: 1335 DR--------KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 777 EK------------WQQEQERLLQERYQK----EQDKLKEEWEKAQKEVE------EEER 814
E+ Q+ +++L Q+R +K EQ ++E ++ +E E E ER
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 815 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 874
++ EEE+++ ++ F ++ E + D ++E+Q RR ++
Sbjct: 1447 KFLEEEQQLRQERHRKF------REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 875 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQL 920
+ + +L + E LEE+ L H K + E+ QL
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQL------HRQQRQRKFLQEEQQL 1540
Score = 38.1 bits (87), Expect = 0.044
Identities = 21/66 (31%), Positives = 41/66 (62%), Gaps = 11/66 (16%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY---------YEEE 820
E++ RRQE+ QQ ++ ++R +E+++L++E E+ Q +E +R++ E+E
Sbjct: 1537 EQQLRRQERGQQRRQD--RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 821 RKIIED 826
RK +ED
Sbjct: 1595 RKFMED 1600
Score = 37.7 bits (86), Expect = 0.058
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 39/320 (12%)
Query: 151 KEFEGLLAQMRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR---HGRD-DSFDSLD 206
+E E L Q RK E + ++ W+ E+ +++ + GR+ + F L+
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQ-----WEPEKENAVRDNKVYCKGRENEQFRQLE 1254
Query: 207 SFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPF 266
R RQ+ L G R + E R+ + + E K A
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQERDREQE----RRRWQQRDRHFPEEEQLEREEQKEA--- 1307
Query: 267 NQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGG--ERPFRYGPRTPVSDDAE 324
+ KS + + R++K R+E + + L E+P R R + E
Sbjct: 1308 -KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 325 STSMFDMR--CEEEAAVQPHSRARQ---EQLQLI----NNQLREEDDKW----QDDLARW 371
R EEE ++ R R+ E+ QL QLR++ D+ + L+R
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 372 KSRR--RSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEA 429
+ R R Q + ++E ERK +E+ + ER + + +++QE+E E++LH
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEE---EQQLRQERHRKFREEEQLLQERE--EQQLHRQ 1481
Query: 430 YKNARSQEEAEGILQQYIER 449
++ + EE + + +Q +R
Sbjct: 1482 ERDRKFLEEEQQLRRQERDR 1501
Score = 37.7 bits (86), Expect = 0.058
Identities = 21/59 (35%), Positives = 38/59 (64%), Gaps = 1/59 (1%)
Query: 768 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 826
+ E++ RRQE+ ++ + Q R Q+ + K +EE E+ ++E E+E+ R E RKI+E+
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREE-EQLRQETEQEQLRRQERYRKILEE 1752
Score = 37.4 bits (85), Expect = 0.075
Identities = 42/208 (20%), Positives = 83/208 (39%), Gaps = 17/208 (8%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 344
R++ EREE R S G E P + + ++R + Q R
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETE-----EFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 345 ARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSE 404
RQ+++ +EE++K W+ R + ++ K +EE + ++ L E+
Sbjct: 232 ERQDRV------FQEEEEK------EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 405 RRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPK 464
+ + + RE +E+++++R E + +EE ++ E+ E ER E
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 465 ILERSHSTEPNLSSFLNDPNPMKYLRQQ 492
E+ E L + + LR++
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRRE 367
Score = 37.0 bits (84), Expect = 0.098
Identities = 22/64 (34%), Positives = 41/64 (64%), Gaps = 7/64 (10%)
Query: 770 EEERRRQEKWQQ--EQERLLQERYQK-----EQDKLKEEWEKAQKEVEEEERRYYEEERK 822
+E+ RRQE++++ E+E+L ER ++ E+D+ E E+ ++E EE++ R E +RK
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Query: 823 IIED 826
E+
Sbjct: 1797 FREE 1800
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 10/117 (8%)
Query: 330 DMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVS--QDLIKKEE 387
D + EE + +Q + Q + + REE+ + L R + R+ + Q L ++E
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ----LRRQERERKFLQEEQQLRRQEL 1721
Query: 388 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEK----ERRERELHEAYKNARSQEEAE 440
ERK E+ ++ E+ + + YR+I++E+ ER E++L ++ + +EE +
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 35.8 bits (81), Expect = 0.22
Identities = 18/56 (32%), Positives = 38/56 (67%), Gaps = 2/56 (3%)
Query: 768 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 823
+ E + RRQE+ ++Q R ++R +E+++L +E E+ Q +E +R++ EEE+++
Sbjct: 1647 EEEPQLRRQER--EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Score = 35.4 bits (80), Expect = 0.29
Identities = 31/152 (20%), Positives = 71/152 (46%), Gaps = 13/152 (8%)
Query: 287 KKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRAR 346
+K ER+E R+ ++ R + + E + R E++ + R
Sbjct: 279 RKLERQELRRERQEEEQQ---QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 347 QEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERR 406
++QL+ RE++++ + L R + R Q +++E+E ++ E+ L E R
Sbjct: 336 EQQLR------REQEERREQQLRREQEEERREQQ--LRREQEEERREQQLRREQ-QLRRE 386
Query: 407 KSIKTYREIVQEKE-RRERELHEAYKNARSQE 437
+ ++ +++ +E++ RRE++L + R Q+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Score = 35.4 bits (80), Expect = 0.29
Identities = 21/57 (36%), Positives = 36/57 (63%), Gaps = 4/57 (7%)
Query: 768 DPEEERRRQEKWQQ-EQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 823
+ E++ RRQE QQ QER +R +E ++L +E E+ Q +E +R++ EEE ++
Sbjct: 1599 EDEQQLRRQEGQQQLRQER---DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Score = 35.0 bits (79), Expect = 0.37
Identities = 18/57 (31%), Positives = 35/57 (61%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 826
E+ER+ E QQ + + Q++ ++E+D+ E E+ +E EE++ E +RK +E+
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Score = 34.3 bits (77), Expect = 0.64
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 11/126 (8%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRR------RSVSQDLIKKEE 387
+EE ++ R +Q + Q + + REE+ Q+ + SR+ R Q + ++E+
Sbjct: 1535 QEEQQLRRQERGQQRR-QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 388 ERKKM--EKLLAGEDGTSE-RRKSIKTYREIVQ-EKERRERELHEAYKNARSQEEAEGIL 443
ERK M E+ L ++G + R++ + +RE Q +ER E++LH ++ + EE +
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 444 QQYIER 449
+Q E+
Sbjct: 1654 RQEREQ 1659
Score = 34.3 bits (77), Expect = 0.64
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 13/123 (10%)
Query: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDD---KWQDDLARWKSRRRSVSQ 380
E + R E++ Q R +E+ QL Q REE + +D RW+ + + +
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQL--RQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 381 DLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKER-----RERELHEAYKNARS 435
+ +ER + + E+ + + KS + +E+ QE+E+ RER+L E + +
Sbjct: 1833 QEQRLRQERDRQYR---AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Query: 436 QEE 438
+EE
Sbjct: 1890 KEE 1892
Score = 34.3 bits (77), Expect = 0.64
Identities = 20/64 (31%), Positives = 39/64 (60%), Gaps = 12/64 (18%)
Query: 768 DPEEERRRQEK---WQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKII 824
+ +E+R RQE+ ++ E++ QE+ ++E+ +L W+ EEE++R E ERK+
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL---WQ------EEEQKRRQERERKLR 1881
Query: 825 EDTV 828
E+ +
Sbjct: 1882 EEHI 1885
Score = 34.3 bits (77), Expect = 0.64
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 765 WAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYE 818
+A + R QE WQ+E+ Q+R Q+ + KL+EE + Q++ E+ R+ E
Sbjct: 1851 FATQEKSRREEQELWQEEE----QKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
Score = 33.9 bits (76), Expect = 0.83
Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 5/125 (4%)
Query: 346 RQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER 405
++ + Q ++ Q R+ ++ R + R + + D +K E +++ L GE+ R
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL--LQEGEEQQLRR 1686
Query: 406 RKSIKTYREIVQEKERRERE---LHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 462
++ + +RE Q+ R+ERE L E + R + E + ++ + + T E + +
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 463 PKILE 467
KILE
Sbjct: 1747 RKILE 1751
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 11/62 (17%)
Query: 773 RRRQEKW-QQEQERLLQERYQ----------KEQDKLKEEWEKAQKEVEEEERRYYEEER 821
++RQ K+ Q+EQ+ QER Q +E+++L++E E+ Q +E +R++ EE+
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 822 KI 823
K+
Sbjct: 1587 KV 1588
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 8/62 (12%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQ--------KEVEEEERRYYEEER 821
EEE+ R E+ +Q+ R ++R +E+++L++E E+ Q K EEE+ R EE+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 822 KI 823
++
Sbjct: 1811 QL 1812
Score = 33.1 bits (74), Expect = 1.4
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 6/114 (5%)
Query: 335 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 394
EE + R R+ +L+ + +E++ K+ +D + RR Q +++E +RK E
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE---QQLRRQEGQQQLRQERDRKFRED 1624
Query: 395 ---LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ 445
L E+ R++ + + E + R+ERE + R E E +LQ+
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Score = 32.7 bits (73), Expect = 1.9
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 344
R+++ RE+ + ER + R + E + + E ++ +
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 345 ARQEQLQLINNQLREEDD-KWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTS 403
R+EQ QLR E + + L R + RR ++ +++ E+++ E+ L E
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ--E 452
Query: 404 ERRKSIKTYREIVQEKERRERELHEAYKNARSQEE 438
ERR +K RE +E ER E+E + +EE
Sbjct: 453 ERRDWLK--RE--EETERHEQERRKQQLKRDQEEE 483
Score = 32.7 bits (73), Expect = 1.9
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQ------LREEDDKWQDD---LARWKSRRRSVSQDLIK 384
EE+ Q R +E+ QL+ + +E D K+ ++ L R + R+ Q+L
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 385 KEEERKKMEKLLAGEDGTSERR-----KSIKTYREIVQEKERRERELHEAYKNARSQEEA 439
+E ERK +E+ +R+ + ++ Q ++ R+R+ E + + +EE
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 440 EGILQQYIERFTISEAVLERLEMPK 464
+ Q+ +F + E + R E +
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQER 1595
Score = 32.0 bits (71), Expect = 3.2
Identities = 16/54 (29%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
Query: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 823
+ +R+ +E+ Q QER Q+ ++E+D+ K E+ + +E+ER++ E+E+++
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDR-KFRLEEQKVRRQEQERKFMEDEQQL 1604
Score = 32.0 bits (71), Expect = 3.2
Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 23/189 (12%)
Query: 770 EEERRRQEKWQQEQERLLQERYQK----EQDKLKEEWEKAQKEVEEEERRY-------YE 818
EEE+ RQE+ +Q+ R QER +K EQ ++E E+ E E++ RR E
Sbjct: 1559 EEEQLRQEREEQQLSR--QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 819 EERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQ-- 876
+RK ED + + E + + + +DR++++ Q
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 877 --GDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 934
G++ L + R+ EE+ L K + E+ QL + Q
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERER------KFLQEEQQLRRQELERKFREEEQ 1730
Query: 935 LAQDPSQNQ 943
L Q+ Q Q
Sbjct: 1731 LRQETEQEQ 1739
Score = 30.8 bits (68), Expect = 7.0
Identities = 21/56 (37%), Positives = 38/56 (67%), Gaps = 6/56 (10%)
Query: 770 EEERRRQEKWQQ--EQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 823
E++ RRQE ++ E+E+L QE EQ++L+ + E+ +K +EEE+ R EE+++
Sbjct: 1713 EQQLRRQELERKFREEEQLRQET---EQEQLRRQ-ERYRKILEEEQLRPEREEQQL 1764
Score = 30.4 bits (67), Expect = 9.2
Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 32/165 (19%)
Query: 330 DMRCEEEAAV--QPHSRARQEQLQLINNQLREEDDKWQDD--LARWKSRRRSVSQDLIKK 385
+++ EEE + + +R RQE + Q R+E++ Q++ L R + +R ++
Sbjct: 1055 ELQQEEEQLLGEERETRRRQE----LERQYRKEEELQQEEEQLLREEPEKRR------RQ 1104
Query: 386 EEER---------KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQ 436
E ER ++ E+LL E R++ + YRE + ++ E+ L E + R Q
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 437 E-----EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNL 476
E E LQQ E+ E R E ER + E L
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQER----ERQYREEEEL 1205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,561,925
Number of Sequences: 37866
Number of extensions: 2418987
Number of successful extensions: 26654
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 836
Number of HSP's that attempted gapping in prelim test: 13255
Number of HSP's gapped (non-prelim): 8139
length of query: 1056
length of database: 18,247,518
effective HSP length: 113
effective length of query: 943
effective length of database: 13,968,660
effective search space: 13172446380
effective search space used: 13172446380
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.