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Search of human proteins with 157785672
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157785672 tetratricopeptide repeat domain 24 [Homo sapiens]
(302 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157785672 tetratricopeptide repeat domain 24 [Homo sapiens] 621 e-178
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 63 4e-10
gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg... 54 1e-07
gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg... 54 1e-07
gi|164519122 LGN protein [Homo sapiens] 51 1e-06
gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchan... 37 0.028
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 35 0.081
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 35 0.081
gi|222446647 coiled-coil domain containing 153 [Homo sapiens] 34 0.14
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 33 0.24
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 33 0.24
gi|110227615 echinoderm microtubule associated protein like 3 [H... 33 0.24
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re... 33 0.24
gi|229094128 active breakpoint cluster region-related protein i... 33 0.31
gi|38679957 active breakpoint cluster region-related protein is... 33 0.31
gi|38679954 active breakpoint cluster region-related protein is... 33 0.31
gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo sap... 33 0.31
gi|83415184 transmembrane and tetratricopeptide repeat containin... 33 0.31
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 33 0.40
gi|239755722 PREDICTED: hypothetical protein [Homo sapiens] 32 0.53
gi|239750240 PREDICTED: hypothetical protein [Homo sapiens] 32 0.53
gi|239744540 PREDICTED: hypothetical protein XP_002343179 [Homo ... 32 0.53
gi|90903231 huntingtin [Homo sapiens] 32 0.69
gi|239753673 PREDICTED: hypothetical protein [Homo sapiens] 32 0.90
gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens] 32 0.90
gi|76781485 vascular endothelial growth factor A isoform f precu... 31 1.2
gi|76781484 vascular endothelial growth factor A isoform e precu... 31 1.2
gi|76781483 vascular endothelial growth factor A isoform d precu... 31 1.2
gi|76781482 vascular endothelial growth factor A isoform c precu... 31 1.2
gi|76781481 vascular endothelial growth factor A isoform b precu... 31 1.2
>gi|157785672 tetratricopeptide repeat domain 24 [Homo sapiens]
Length = 302
Score = 621 bits (1601), Expect = e-178
Identities = 302/302 (100%), Positives = 302/302 (100%)
Query: 1 MAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHAL 60
MAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHAL
Sbjct: 1 MAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHAL 60
Query: 61 QAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLAD 120
QAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLAD
Sbjct: 61 QAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLAD 120
Query: 121 TVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEF 180
TVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEF
Sbjct: 121 TVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEF 180
Query: 181 EEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKA 240
EEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKA
Sbjct: 181 EEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKA 240
Query: 241 SIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPMESGICT 300
SIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPMESGICT
Sbjct: 241 SIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPMESGICT 300
Query: 301 IV 302
IV
Sbjct: 301 IV 302
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 62.8 bits (151), Expect = 4e-10
Identities = 34/99 (34%), Positives = 53/99 (53%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A+NALG Y +A ++H++ + V R Q + G+LA A LG H A +Y + L
Sbjct: 523 AYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLN 582
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
AR+ D++ + +A LG G+Y QA YY++ L
Sbjct: 583 IARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYL 621
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/95 (30%), Positives = 51/95 (53%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H A+G+ Q+A +K + +G+ + + +++G L SQLG+++ A L
Sbjct: 927 HRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNI 986
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYK 97
ARD D + A GLG ++G+YD AL+Y++
Sbjct: 987 ARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQ 1021
Score = 48.5 bits (114), Expect = 7e-06
Identities = 28/111 (25%), Positives = 54/111 (48%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A+ +LGN +++ + Q+ D+ ++G + + R+ G+L A G+++ A N+ H L
Sbjct: 243 AYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLV 302
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
A D + A LG +G Y AL +K+ + ++ D + E
Sbjct: 303 LAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSE 353
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/99 (26%), Positives = 49/99 (49%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A + + + A+++H++ + + R +GR+ +L GD+ A + L
Sbjct: 443 AARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLC 502
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
A++ D Q +A +G A LG YDQA+KY+++ L
Sbjct: 503 IAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQEL 541
Score = 43.5 bits (101), Expect = 2e-04
Identities = 26/98 (26%), Positives = 45/98 (45%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H G+Y A + H+ + + QGR++G++ A + LG + A + LQ
Sbjct: 484 HQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQI 543
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
+ + D Q L A LG +D+AL++Y+ L
Sbjct: 544 SMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHL 581
Score = 42.4 bits (98), Expect = 5e-04
Identities = 25/107 (23%), Positives = 51/107 (47%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
AH LGNYQEA +++++ L + + Q +++ +L A L + A + + L
Sbjct: 643 AHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLS 702
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPD 108
A+ + + +++A LG + A+K+Y++ L + D
Sbjct: 703 LAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKD 749
Score = 41.6 bits (96), Expect = 9e-04
Identities = 24/98 (24%), Positives = 51/98 (52%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
+ ALG+Y+EA +++++ + S+ + +Q +++ L +G + A + L
Sbjct: 887 YEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVV 946
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
A + G+ + QA LG+ ++LG Y+QA+ + L
Sbjct: 947 AHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQL 984
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/107 (25%), Positives = 47/107 (43%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A++ N+ +A +H +L + ++ + R++ L A + D + A+ + L
Sbjct: 403 AYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLG 462
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPD 108
A D D + +A LG G YD ALK +K L Q+ D
Sbjct: 463 IAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSD 509
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/103 (23%), Positives = 47/103 (45%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
+ A+G+Y A H++ L + R G++ +GD + A + L+
Sbjct: 324 YTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKI 383
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQK 105
A+D G+ + + +A LG+A +D+A+ Y+ L Q+
Sbjct: 384 AKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQE 426
Score = 40.8 bits (94), Expect = 0.001
Identities = 25/98 (25%), Positives = 39/98 (39%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
+ +G Y A ++HQ + QGR++G+L LG + A L
Sbjct: 1007 YQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSI 1066
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
A D+ + + LG L Y QA+ Y +E L
Sbjct: 1067 AAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGL 1104
Score = 40.4 bits (93), Expect = 0.002
Identities = 23/108 (21%), Positives = 54/108 (50%)
Query: 5 ALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAAR 64
A+G+++ A + H++ + +G + E+ R++ +L A + A + + L+ A+
Sbjct: 366 AMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQ 425
Query: 65 DSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
+ + + +A GLG AA + ++A +Y+++ L + D E
Sbjct: 426 ELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAE 473
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 15 FHQKAADLHGSVGQR--WEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQ 72
F Q+ A L G ++GR++G+L LGD++ A Y L A+ M+ Q
Sbjct: 857 FEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQ 916
Query: 73 WQACEGLGAAAARLGQYDQALKYYKEAL 100
+A GLG +G QAL +++ L
Sbjct: 917 AKAYRGLGNGHRAMGSLQQALVCFEKRL 944
Score = 37.7 bits (86), Expect = 0.013
Identities = 23/99 (23%), Positives = 48/99 (48%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H+ LGNY++A ++ ++ + R + + L Q+G++ A + LQ
Sbjct: 967 HSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQI 1026
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALA 101
A ++ + Q +A LG LG +++A+ Y ++ L+
Sbjct: 1027 AEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLS 1065
Score = 37.4 bits (85), Expect = 0.016
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 12 AREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKG 71
A +F+++ L V R + ++ +L A + + A + L+ ++ D+ G
Sbjct: 733 AIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPG 792
Query: 72 QWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLV 115
+ +A L A LG+Y A K Y+E L QK D E V
Sbjct: 793 ECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQV 836
Score = 35.4 bits (80), Expect = 0.062
Identities = 21/94 (22%), Positives = 43/94 (45%)
Query: 7 GNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDS 66
GNY+EA H+ L + R + SL + +GD+ A ++ + A+ S
Sbjct: 288 GNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQS 347
Query: 67 GDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
D + + +GA +G ++ A++ +++ L
Sbjct: 348 KDELSEARELGNMGAVYIAMGDFENAVQCHEQHL 381
Score = 34.3 bits (77), Expect = 0.14
Identities = 22/77 (28%), Positives = 35/77 (45%)
Query: 32 QGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQ 91
+G F +L+ A LG+ + + L A+ GD G+ +A LG+A G Y +
Sbjct: 233 RGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYRE 292
Query: 92 ALKYYKEALAQCQKEPD 108
AL ++ L K D
Sbjct: 293 ALTNHRHQLVLAMKLKD 309
Score = 33.5 bits (75), Expect = 0.24
Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Query: 5 ALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAAR---DNYLHALQ 61
ALG Y A + +++ DL + + + +G++ + + A + L LQ
Sbjct: 806 ALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQ 865
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQ 104
+ + + +A LG LG Y++A+KYY++ L+ Q
Sbjct: 866 QLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQ 908
Score = 33.1 bits (74), Expect = 0.31
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H + G Y +A ++++ L + +G+ +L +A LG+++ A Y L
Sbjct: 604 HCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLAL 663
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDS-VRERLVAKLAD 120
A+D D Q +A LG A L + +A + K L+ Q +S + R + L D
Sbjct: 664 AKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGD 722
>gi|224548927 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform a [Homo sapiens]
Length = 675
Score = 54.3 bits (129), Expect = 1e-07
Identities = 34/110 (30%), Positives = 51/110 (46%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H LGN+ EA FH++ + G + + R++ +L A LG A + Y LQ
Sbjct: 219 HYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQL 278
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
+R D + QAC LG L Y++A +Y+ L Q+ D V E
Sbjct: 279 SRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGE 328
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/176 (26%), Positives = 80/176 (45%), Gaps = 16/176 (9%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
AH LG + A E+++K L + + + ++ SL + L D++ A + +L L
Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADT 121
A++ D G+ +AC LG A +G+ QAL + K+ L Q+ D E T
Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHGEL-------T 370
Query: 122 VRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKA-GSSTAGVQHRSSSGWE 176
R +AQ+ LV GRL +P + + + +A G+ Q S+ W+
Sbjct: 371 ARMNVAQLQLVL--------GRLTSPAASEKPDLAGYEAQGARPKRTQRLSAETWD 418
Score = 53.1 bits (126), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%)
Query: 11 EAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMK 70
+A EF+++ L +G R QGR++G+L LG+ A + L A++ GD
Sbjct: 187 KASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKA 246
Query: 71 GQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
+ +A LG A LG++D A +YYK+ L ++ D E
Sbjct: 247 AERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVE 288
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/77 (31%), Positives = 37/77 (48%)
Query: 36 FGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKY 95
+ L A L +H A + + H L AR GD G+ +A LG LG++D+A
Sbjct: 69 YSQLGNAYFYLKEHGRALEYHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAAVC 128
Query: 96 YKEALAQCQKEPDSVRE 112
+ L+ Q++ D V E
Sbjct: 129 CQRHLSIAQEQGDKVGE 145
Score = 32.3 bits (72), Expect = 0.53
Identities = 19/62 (30%), Positives = 29/62 (46%)
Query: 52 ARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVR 111
A + Y L ++ GD Q +A LG LG + +A ++KE LA ++ D
Sbjct: 188 ASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAA 247
Query: 112 ER 113
ER
Sbjct: 248 ER 249
Score = 31.2 bits (69), Expect = 1.2
Identities = 21/79 (26%), Positives = 36/79 (45%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A+ L + A E+H+ L ++G R + ++ G+L L LG A L
Sbjct: 75 AYFYLKEHGRALEYHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAAVCCQRHLS 134
Query: 62 AARDSGDMKGQWQACEGLG 80
A++ GD G+ +A +G
Sbjct: 135 IAQEQGDKVGEARALYNIG 153
>gi|224548925 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform b [Homo sapiens]
Length = 457
Score = 54.3 bits (129), Expect = 1e-07
Identities = 34/110 (30%), Positives = 51/110 (46%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H LGN+ EA FH++ + G + + R++ +L A LG A + Y LQ
Sbjct: 219 HYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQL 278
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
+R D + QAC LG L Y++A +Y+ L Q+ D V E
Sbjct: 279 SRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGE 328
Score = 53.1 bits (126), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%)
Query: 11 EAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMK 70
+A EF+++ L +G R QGR++G+L LG+ A + L A++ GD
Sbjct: 187 KASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKA 246
Query: 71 GQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
+ +A LG A LG++D A +YYK+ L ++ D E
Sbjct: 247 AERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVE 288
Score = 51.6 bits (122), Expect = 8e-07
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 15/153 (9%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
AH LG + A E+++K L + + + ++ SL + L D++ A + +L L
Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADT 121
A++ D G+ +AC LG A +G+ QAL + K+ L Q+ D E T
Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHGEL-------T 370
Query: 122 VRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAE 154
R +AQ+ LV GRL +P + + +
Sbjct: 371 ARMNVAQLQLVL--------GRLTSPAASEKPD 395
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/77 (31%), Positives = 37/77 (48%)
Query: 36 FGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKY 95
+ L A L +H A + + H L AR GD G+ +A LG LG++D+A
Sbjct: 69 YSQLGNAYFYLKEHGRALEYHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAAVC 128
Query: 96 YKEALAQCQKEPDSVRE 112
+ L+ Q++ D V E
Sbjct: 129 CQRHLSIAQEQGDKVGE 145
Score = 32.3 bits (72), Expect = 0.53
Identities = 19/62 (30%), Positives = 29/62 (46%)
Query: 52 ARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVR 111
A + Y L ++ GD Q +A LG LG + +A ++KE LA ++ D
Sbjct: 188 ASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAA 247
Query: 112 ER 113
ER
Sbjct: 248 ER 249
Score = 31.2 bits (69), Expect = 1.2
Identities = 21/79 (26%), Positives = 36/79 (45%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A+ L + A E+H+ L ++G R + ++ G+L L LG A L
Sbjct: 75 AYFYLKEHGRALEYHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAAVCCQRHLS 134
Query: 62 AARDSGDMKGQWQACEGLG 80
A++ GD G+ +A +G
Sbjct: 135 IAQEQGDKVGEARALYNIG 153
Score = 28.9 bits (63), Expect = 5.8
Identities = 24/99 (24%), Positives = 40/99 (40%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
+ L +Y+ A E+H + + + R +GR+ SL A +G A LQ
Sbjct: 299 YTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQI 358
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALA 101
+++ GD G+ A + LG+ K LA
Sbjct: 359 SQEIGDRHGELTARMNVAQLQLVLGRLTSPAASEKPDLA 397
>gi|164519122 LGN protein [Homo sapiens]
Length = 684
Score = 51.2 bits (121), Expect = 1e-06
Identities = 32/103 (31%), Positives = 54/103 (52%)
Query: 10 QEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDM 69
Q A +F+++ L ++G R QGR+FG+L LG+ + A + L A++ GD
Sbjct: 179 QAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDK 238
Query: 70 KGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
+ +A LG A LG+++ A +YYK+ L ++ D E
Sbjct: 239 AAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVE 281
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A+ LG ++ A E+++K L + R + +S SL + L D++ A D +L L
Sbjct: 251 AYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLA 310
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKL 118
A++ D G+ +AC LG A LG +DQA+ ++ E + +E L A+L
Sbjct: 311 IAQELNDRIGEGRACWSLGNAYTALGNHDQAM-HFAEKHLEISREVGDKSGELTARL 366
Score = 50.8 bits (120), Expect = 1e-06
Identities = 31/110 (28%), Positives = 54/110 (49%)
Query: 3 HNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQA 62
H LGN+++A H++ + G + + R++ +L A LG+ + A + Y L
Sbjct: 212 HYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLL 271
Query: 63 ARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE 112
AR D + Q+C LG L Y++A+ Y+ + LA Q+ D + E
Sbjct: 272 ARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGE 321
Score = 35.8 bits (81), Expect = 0.048
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 36 FGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKY 95
+ L A L D+ A + + H L AR GD G+ +A LG LG +D
Sbjct: 65 YSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFD----- 119
Query: 96 YKEALAQCQKEPDSVRE 112
EA+ CQ+ D RE
Sbjct: 120 --EAIVCCQRHLDISRE 134
Score = 31.6 bits (70), Expect = 0.90
Identities = 21/79 (26%), Positives = 37/79 (46%)
Query: 2 AHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQ 61
A+ L +Y +A E+H L ++G + + ++ G+L L LG+ A L
Sbjct: 71 AYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLD 130
Query: 62 AARDSGDMKGQWQACEGLG 80
+R+ D G+ +A LG
Sbjct: 131 ISRELNDKVGEARALYNLG 149
>gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchange
factor 4 [Homo sapiens]
Length = 368
Score = 36.6 bits (83), Expect = 0.028
Identities = 47/186 (25%), Positives = 67/186 (36%), Gaps = 55/186 (29%)
Query: 153 AEGTPAKAGSSTAGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPG---------- 202
AE +A S G+ HRS +D E+ Q+KK ++ A+V R G
Sbjct: 44 AETVRGEAPSQPRGIPHRSPVSVDDLWLEK-TQRKKLQKQAHVERRLHIGAVHKDGVKCW 102
Query: 203 RPELCFLPGTVN---HSHHLASSCPT------FTKHTPCRGTVLGKASIYSPG------- 246
R + P ++N SH L+ S PT + +HTP T L + +P
Sbjct: 103 RKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSP 162
Query: 247 ------------PRA----------------HLPFVGPGPPRAEYPSILVPNGPQANRSS 278
PRA H P PP PS+ + GP R+
Sbjct: 163 SQLTIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQ 222
Query: 279 RWPRES 284
+ P ES
Sbjct: 223 QCPSES 228
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 35.0 bits (79), Expect = 0.081
Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 20/120 (16%)
Query: 129 VGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSS---TAGVQHRSSSGWEDEEFEEGHQ 185
+GL T +TS P E +P G+S TAG + +SG E+E
Sbjct: 418 IGLPSTSAVTSQP---------KSFENSPGDLGNSSLPTAGYKRAQTSGIEEETV----- 463
Query: 186 KKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASIYSP 245
K+++R N + GPGRP+ N SH SS + G++ + SP
Sbjct: 464 -KEKKRKGNKQSKHGPGRPK--GNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSP 520
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 35.0 bits (79), Expect = 0.081
Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 20/120 (16%)
Query: 129 VGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSS---TAGVQHRSSSGWEDEEFEEGHQ 185
+GL T +TS P E +P G+S TAG + +SG E+E
Sbjct: 418 IGLPSTSAVTSQP---------KSFENSPGDLGNSSLPTAGYKRAQTSGIEEETV----- 463
Query: 186 KKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASIYSP 245
K+++R N + GPGRP+ N SH SS + G++ + SP
Sbjct: 464 -KEKKRKGNKQSKHGPGRPK--GNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSP 520
>gi|222446647 coiled-coil domain containing 153 [Homo sapiens]
Length = 210
Score = 34.3 bits (77), Expect = 0.14
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 9/97 (9%)
Query: 31 EQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAAR----- 85
E RS G +A H D + Q + ++GQ +AC+ AAA
Sbjct: 74 EGARSEGKAIYAEMSRQCHALQEDMQTRSKQLEEEVKGLRGQLEACQREAAAAREEAEQA 133
Query: 86 LGQYDQALKYYKEALAQCQKEPDSV----RERLVAKL 118
LG+ DQAL + +A + + + + +RL+AKL
Sbjct: 134 LGERDQALAQLRAHMADMEAKYEEILHDSLDRLLAKL 170
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 33.5 bits (75), Expect = 0.24
Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 20/136 (14%)
Query: 144 LQAPGGASQAEGTPAKAGSSTAGVQH----------RSSSGWEDEEFEEGHQK-KKEERS 192
L P G S+ G PA AG ++ + R SSG EEG+ K+ +
Sbjct: 825 LSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKP 884
Query: 193 ANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVL--GKASIYSPGPRAH 250
A P R P P L F + S + P + P + +L G AS +PGP A
Sbjct: 885 AGPPPRETPVPPGLDF---NLTESDTVKRR-PKCREREPLQTALLAFGVASA-TPGPAAP 939
Query: 251 LPFVGPG--PPRAEYP 264
LP PG PP + P
Sbjct: 940 LPSPTPGESPPASSLP 955
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 33.5 bits (75), Expect = 0.24
Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 20/136 (14%)
Query: 144 LQAPGGASQAEGTPAKAGSSTAGVQH----------RSSSGWEDEEFEEGHQK-KKEERS 192
L P G S+ G PA AG ++ + R SSG EEG+ K+ +
Sbjct: 907 LSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKP 966
Query: 193 ANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVL--GKASIYSPGPRAH 250
A P R P P L F + S + P + P + +L G AS +PGP A
Sbjct: 967 AGPPPRETPVPPGLDF---NLTESDTVKRR-PKCREREPLQTALLAFGVASA-TPGPAAP 1021
Query: 251 LPFVGPG--PPRAEYP 264
LP PG PP + P
Sbjct: 1022 LPSPTPGESPPASSLP 1037
>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
sapiens]
Length = 896
Score = 33.5 bits (75), Expect = 0.24
Identities = 41/145 (28%), Positives = 54/145 (37%), Gaps = 17/145 (11%)
Query: 143 RLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPG 202
RLQ P + Q GTPA G S A + G Q + E V +++ PG
Sbjct: 45 RLQVPPSSLQGSGTPAPPGDSLAAPPGLPPT-CTPSLVSRGTQTETE-----VELKSSPG 98
Query: 203 RPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAE 262
P L P + S T G + SPGP L + P P RA+
Sbjct: 99 PPGLSNGPPAPQGASEEPSG-------TQSEGGGSSSSGAGSPGPPGILRPLQP-PQRAD 150
Query: 263 YPSILVPNGPQANRSSRWPRESLSR 287
P N ++ S PR+ LSR
Sbjct: 151 TPR---RNSSSSSSPSERPRQKLSR 172
>gi|38569493 potassium voltage-gated channel, subfamily H
(eag-related), member 3 [Homo sapiens]
Length = 1083
Score = 33.5 bits (75), Expect = 0.24
Identities = 29/98 (29%), Positives = 38/98 (38%), Gaps = 15/98 (15%)
Query: 218 HLASSCPTFTKHTPCRGTVLGK---------ASIYSPGPRAHLPFVGPGP-PRAEYPSIL 267
H CP + PC + G AS Y P A G P PR P ++
Sbjct: 913 HREGPCPRASGEGPCPASTSGLLQPLCVDTGASSYCLQPPAGSVLSGTWPHPRPGPPPLM 972
Query: 268 VPN--GPQANRSSRWPRES---LSRSRQRRPMESGICT 300
P GP A++SS WPR + S S P +C+
Sbjct: 973 APWPWGPPASQSSPWPRATAFWTSTSDSEPPASGDLCS 1010
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 33.1 bits (74), Expect = 0.31
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 10 QEAREFHQKAADLHGSVGQRWEQGRSFGSLAFAL-SQLGDHKAARDNYLHALQAARDSGD 68
Q+ E H++ D Q+W+ + G L L SQLG +KA DNY AL+ A
Sbjct: 98 QDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQ 157
Query: 69 MKGQWQ 74
Q+Q
Sbjct: 158 SNNQFQ 163
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 33.1 bits (74), Expect = 0.31
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 10 QEAREFHQKAADLHGSVGQRWEQGRSFGSLAFAL-SQLGDHKAARDNYLHALQAARDSGD 68
Q+ E H++ D Q+W+ + G L L SQLG +KA DNY AL+ A
Sbjct: 144 QDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQ 203
Query: 69 MKGQWQ 74
Q+Q
Sbjct: 204 SNNQFQ 209
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 33.1 bits (74), Expect = 0.31
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 10 QEAREFHQKAADLHGSVGQRWEQGRSFGSLAFAL-SQLGDHKAARDNYLHALQAARDSGD 68
Q+ E H++ D Q+W+ + G L L SQLG +KA DNY AL+ A
Sbjct: 107 QDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQ 166
Query: 69 MKGQWQ 74
Q+Q
Sbjct: 167 SNNQFQ 172
>gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
sapiens]
Length = 592
Score = 33.1 bits (74), Expect = 0.31
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 238 GKASIYSPGPRAHLPFVGPGPPRAEYPSILVPNGP-QANRSSRWPRESLSRSRQRRPMES 296
G A + P P A P GP PP+ + + L P P + +S WP E +SR M +
Sbjct: 503 GFAKVLPPSPWAPAPADGPQPPK-DSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGA 561
Query: 297 G 297
G
Sbjct: 562 G 562
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 33.1 bits (74), Expect = 0.31
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 46 LGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQK 105
LG++ A + Y ALQ A + + LGA G+Y++AL+ Y+EA A Q
Sbjct: 555 LGENSMAEEWYKRALQVAHKA-------EILSPLGALYYNTGRYEEALQIYQEA-AALQP 606
Query: 106 EPDSVRERLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQ 145
+R L LA +T+ A+ + H ++ G L+
Sbjct: 607 SQRELRLALAQVLAVMGQTKEAE--KMTNHIVSEETGCLE 644
Score = 28.1 bits (61), Expect = 10.0
Identities = 29/111 (26%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 7 GNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDS 66
G Y+EA + +Q+AA L S Q +LA L+ +G K A H +
Sbjct: 589 GRYEEALQIYQEAAALQPS------QRELRLALAQVLAVMGQTKEAEKMTNHIV------ 636
Query: 67 GDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAK 117
+ G + L A ++ +D+AL +AL K+P + E K
Sbjct: 637 SEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTK 687
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 32.7 bits (73), Expect = 0.40
Identities = 60/236 (25%), Positives = 90/236 (38%), Gaps = 47/236 (19%)
Query: 77 EGLGAAAARLGQYDQALKYYKEALAQCQKEP-----DSVRERLVAKLADTVRTRL--AQV 129
E L A A+ D+ +E LAQ KE + R+R A T++ L A+
Sbjct: 644 EELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEA 703
Query: 130 GLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSS-----TAGVQ--HRSSSGWEDEEFEE 182
G ++ ++P ++ TP + T V+ R SS +D EE
Sbjct: 704 GKIE-----------ESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREE 752
Query: 183 GHQKKKEERSANVPVRAGPGRPELCFLPGTVNHS---HHLASSCPTFTKHTPCRGTVLGK 239
+KKK++ R+ + + +HS H L S+ T + +
Sbjct: 753 EKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRR---------SR 803
Query: 240 ASIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPME 295
+ SP RAH P R E S+ P A R SR P S R+R R P E
Sbjct: 804 SRSRSPRRRAHSP-----ERRREERSV-----PTAYRVSRSPGASRKRTRSRSPHE 849
>gi|239755722 PREDICTED: hypothetical protein [Homo sapiens]
Length = 164
Score = 32.3 bits (72), Expect = 0.53
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 17/99 (17%)
Query: 208 FLPGTVNHSHHLASSCPT----FTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEY 263
++ G LA +CP F K G + G++ G + HL +G G A
Sbjct: 2 YIEGLAPSRRLLAPACPCRTPPFQKKVGLEGDLAGRSLELPAGAQPHLRRLGAGGRAA-- 59
Query: 264 PSILVPNGPQ--ANRSSRWPRESLSRSRQRRPMESGICT 300
GPQ ++ SSR P S+SRS RP S + +
Sbjct: 60 -------GPQSASSMSSRQPSRSMSRS--TRPSSSSVAS 89
>gi|239750240 PREDICTED: hypothetical protein [Homo sapiens]
Length = 164
Score = 32.3 bits (72), Expect = 0.53
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 17/99 (17%)
Query: 208 FLPGTVNHSHHLASSCPT----FTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEY 263
++ G LA +CP F K G + G++ G + HL +G G A
Sbjct: 2 YIEGLAPSRRLLAPACPCRTPPFQKKVGLEGDLAGRSLELPAGAQPHLRRLGAGGRAA-- 59
Query: 264 PSILVPNGPQ--ANRSSRWPRESLSRSRQRRPMESGICT 300
GPQ ++ SSR P S+SRS RP S + +
Sbjct: 60 -------GPQSASSMSSRQPSRSMSRS--TRPSSSSVAS 89
>gi|239744540 PREDICTED: hypothetical protein XP_002343179 [Homo
sapiens]
Length = 164
Score = 32.3 bits (72), Expect = 0.53
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 17/99 (17%)
Query: 208 FLPGTVNHSHHLASSCPT----FTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEY 263
++ G LA +CP F K G + G++ G + HL +G G A
Sbjct: 2 YIEGLAPSRRLLAPACPCRTPPFQKKVGLEGDLAGRSLELPAGAQPHLRRLGAGGRAA-- 59
Query: 264 PSILVPNGPQ--ANRSSRWPRESLSRSRQRRPMESGICT 300
GPQ ++ SSR P S+SRS RP S + +
Sbjct: 60 -------GPQSASSMSSRQPSRSMSRS--TRPSSSSVAS 89
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 32.0 bits (71), Expect = 0.69
Identities = 17/44 (38%), Positives = 25/44 (56%)
Query: 85 RLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 128
RL QY Q L+ + L QC KE + +RL ++AD + LA+
Sbjct: 1579 RLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADIILPMLAK 1622
>gi|239753673 PREDICTED: hypothetical protein [Homo sapiens]
Length = 380
Score = 31.6 bits (70), Expect = 0.90
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 247 PRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRES 284
P+ HL GPG A+ P + + P A R S WPR++
Sbjct: 279 PQCHL-INGPGFAEAKGPMVAAGSSPPAGRFSMWPRDA 315
>gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]
Length = 672
Score = 31.6 bits (70), Expect = 0.90
Identities = 21/99 (21%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 4 NALGNYQEAREFHQKAADLHGSVGQRWEQ--GRSFGSLAFALSQLGDHKAARDNYLHALQ 61
+A G+ Q+A + +K + + ++ G + + A +LG +AA ++ L+
Sbjct: 289 SAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLE 348
Query: 62 AARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEAL 100
A++ + +A + +G AR+G++ QA+ ++E +
Sbjct: 349 IAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKI 387
>gi|76781485 vascular endothelial growth factor A isoform f
precursor [Homo sapiens]
Length = 327
Score = 31.2 bits (69), Expect = 1.2
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 7/116 (6%)
Query: 149 GASQAEGTPAKAGSST-AGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELC 207
G S+ G +AG + +G +SSG E+ + EEG +++++E R G +P
Sbjct: 60 GCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSW 119
Query: 208 FLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASI------YSPGPRAHLPFVGPG 257
V A+ P RG + + +SP R GPG
Sbjct: 120 TGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPG 175
>gi|76781484 vascular endothelial growth factor A isoform e
precursor [Homo sapiens]
Length = 354
Score = 31.2 bits (69), Expect = 1.2
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 7/116 (6%)
Query: 149 GASQAEGTPAKAGSST-AGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELC 207
G S+ G +AG + +G +SSG E+ + EEG +++++E R G +P
Sbjct: 60 GCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSW 119
Query: 208 FLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASI------YSPGPRAHLPFVGPG 257
V A+ P RG + + +SP R GPG
Sbjct: 120 TGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPG 175
>gi|76781483 vascular endothelial growth factor A isoform d
precursor [Homo sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 1.2
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 7/116 (6%)
Query: 149 GASQAEGTPAKAGSST-AGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELC 207
G S+ G +AG + +G +SSG E+ + EEG +++++E R G +P
Sbjct: 60 GCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSW 119
Query: 208 FLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASI------YSPGPRAHLPFVGPG 257
V A+ P RG + + +SP R GPG
Sbjct: 120 TGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPG 175
>gi|76781482 vascular endothelial growth factor A isoform c
precursor [Homo sapiens]
Length = 389
Score = 31.2 bits (69), Expect = 1.2
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 7/116 (6%)
Query: 149 GASQAEGTPAKAGSST-AGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELC 207
G S+ G +AG + +G +SSG E+ + EEG +++++E R G +P
Sbjct: 60 GCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSW 119
Query: 208 FLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASI------YSPGPRAHLPFVGPG 257
V A+ P RG + + +SP R GPG
Sbjct: 120 TGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPG 175
>gi|76781481 vascular endothelial growth factor A isoform b
precursor [Homo sapiens]
Length = 395
Score = 31.2 bits (69), Expect = 1.2
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 7/116 (6%)
Query: 149 GASQAEGTPAKAGSST-AGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELC 207
G S+ G +AG + +G +SSG E+ + EEG +++++E R G +P
Sbjct: 60 GCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSW 119
Query: 208 FLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASI------YSPGPRAHLPFVGPG 257
V A+ P RG + + +SP R GPG
Sbjct: 120 TGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPG 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,614,966
Number of Sequences: 37866
Number of extensions: 699659
Number of successful extensions: 2992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 2853
Number of HSP's gapped (non-prelim): 270
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.