BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157364934 fibrosin [Homo sapiens] (460 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157364934 fibrosin [Homo sapiens] 961 0.0 gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 261 7e-70 gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 239 4e-63 gi|217416343 fibrosin-like 1 [Homo sapiens] 215 8e-56 gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 2e-10 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 1e-09 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 61 2e-09 gi|110832843 TBP-associated factor 4 [Homo sapiens] 60 3e-09 gi|19924097 synapsin I isoform Ib [Homo sapiens] 59 7e-09 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 59 9e-09 gi|19924099 synapsin I isoform Ia [Homo sapiens] 58 2e-08 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 58 2e-08 gi|154146199 sal-like 3 [Homo sapiens] 58 2e-08 gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo ... 56 8e-08 gi|210032580 SET domain containing 1B [Homo sapiens] 55 1e-07 gi|239757043 PREDICTED: functional smad suppressing element 18 [... 55 1e-07 gi|239751555 PREDICTED: functional smad suppressing element 18 [... 55 1e-07 gi|239746067 PREDICTED: functional smad suppressing element 18 [... 55 1e-07 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 55 2e-07 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 55 2e-07 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 55 2e-07 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 55 2e-07 gi|26190608 synaptojanin 2 [Homo sapiens] 53 7e-07 gi|102469037 jun D proto-oncogene [Homo sapiens] 52 1e-06 gi|40353727 synaptopodin isoform A [Homo sapiens] 52 1e-06 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 52 1e-06 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 52 1e-06 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 51 2e-06 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 51 2e-06 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 51 2e-06 >gi|157364934 fibrosin [Homo sapiens] Length = 460 Score = 961 bits (2484), Expect = 0.0 Identities = 460/460 (100%), Positives = 460/460 (100%) Query: 1 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP 60 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP Sbjct: 1 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP 60 Query: 61 VPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPC 120 VPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPC Sbjct: 61 VPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPC 120 Query: 121 LPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSF 180 LPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSF Sbjct: 121 LPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSF 180 Query: 181 ASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRP 240 ASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRP Sbjct: 181 ASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRP 240 Query: 241 PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES 300 PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES Sbjct: 241 PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES 300 Query: 301 VRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFL 360 VRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFL Sbjct: 301 VRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFL 360 Query: 361 EPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPG 420 EPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPG Sbjct: 361 EPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPG 420 Query: 421 TPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR 460 TPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR Sbjct: 421 TPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR 460 >gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sapiens] Length = 1259 Score = 261 bits (668), Expect = 7e-70 Identities = 132/298 (44%), Positives = 193/298 (64%), Gaps = 17/298 (5%) Query: 1 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNP-ELPPRLG 59 MF+KYP K++ +RH+ + ++PPAV G+PP +PP FGSLQGAFQPK++NP ++ R G Sbjct: 563 MFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPG 622 Query: 60 PVPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEK----MKGDSHKLDF-- 113 VP L QK ++ D FRP LRKPGKWCAMHV +A+ I HQ+K M+ D HKLDF Sbjct: 623 TVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL 682 Query: 114 RNDLLPCLPGP--YGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHI 171 + + L PGP +GA+ +L+ P++LF+A GA H PF P H FL+P+ H+ Sbjct: 683 KPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPF-GPPPHHSNFLNPAAHL 741 Query: 172 DPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSP 231 +PF RP++F LAA+ AFGGLG+P+ ++F K+ P F++P +PW RLHR+P Sbjct: 742 EPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSV-QNFSNPHEPWNRLHRTP 800 Query: 232 LTFPA---WVRPPEAARTPGS---DKERPVERREPSITKEEKDRDLPFSRPQLRVSPA 283 +FP W++P E R+ + D++R V++R+ S++K++K+R+ R SPA Sbjct: 801 PSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPA 858 Score = 36.2 bits (82), Expect = 0.064 Identities = 28/71 (39%), Positives = 33/71 (46%), Gaps = 13/71 (18%) Query: 394 RLYGLEPA-------HPLLYSRLAP----PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP 442 RL+ + PA HP L + P P A LL+KTPP A L APPPL+ Sbjct: 1166 RLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLIS 1225 Query: 443 --APRPSSPPR 451 RP SP R Sbjct: 1226 TLGGRPVSPRR 1236 >gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo sapiens] Length = 1235 Score = 239 bits (610), Expect = 4e-63 Identities = 124/297 (41%), Positives = 180/297 (60%), Gaps = 39/297 (13%) Query: 1 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP 60 MF+KYP K++ +RH+ + ++PPAV G+PP +PP FGSLQGAFQPK T+P Sbjct: 563 MFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDP-------- 614 Query: 61 VPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEK----MKGDSHKLDF--R 114 FRP LRKPGKWCAMHV +A+ I HQ+K M+ D HKLDF + Sbjct: 615 ---------------FRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLK 659 Query: 115 NDLLPCLPGP--YGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHID 172 + L PGP +GA+ +L+ P++LF+A GA H PF P H FL+P+ H++ Sbjct: 660 PEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPF-GPPPHHSNFLNPAAHLE 718 Query: 173 PFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPL 232 PF RP++F LAA+ AFGGLG+P+ ++F K+ P F++P +PW RLHR+P Sbjct: 719 PFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSV-QNFSNPHEPWNRLHRTPP 777 Query: 233 TFPA---WVRPPEAARTPGS---DKERPVERREPSITKEEKDRDLPFSRPQLRVSPA 283 +FP W++P E R+ + D++R V++R+ S++K++K+R+ R SPA Sbjct: 778 SFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPA 834 Score = 36.2 bits (82), Expect = 0.064 Identities = 28/71 (39%), Positives = 33/71 (46%), Gaps = 13/71 (18%) Query: 394 RLYGLEPA-------HPLLYSRLAP----PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP 442 RL+ + PA HP L + P P A LL+KTPP A L APPPL+ Sbjct: 1142 RLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLIS 1201 Query: 443 --APRPSSPPR 451 RP SP R Sbjct: 1202 TLGGRPVSPRR 1212 >gi|217416343 fibrosin-like 1 [Homo sapiens] Length = 1045 Score = 215 bits (547), Expect = 8e-56 Identities = 209/570 (36%), Positives = 261/570 (45%), Gaps = 130/570 (22%) Query: 2 FEKYPGKMEG-LFRHNP---YTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNP-ELPP 56 F+KY K++ FRH+ + +FPPA+PGLP LP FGSLQGAFQPK ++P Sbjct: 478 FDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVV 537 Query: 57 RLGPVPSGLSQKGTQIPDHFRP-------------------PL------RKPGKWCAMHV 91 ++ G Q T +P RP PL +KPG+WCA+HV Sbjct: 538 KVSTCWEGPWQGRTLVPPG-RPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHV 596 Query: 92 RVAYMILRHQEKMKG---DSHKLDF--RNDLL--PCLPGPYGALPPGQELSHPASLFTAT 144 ++A+ I RHQ+K+K D HKL+ + DL P PG + Q+L+ P LF +T Sbjct: 597 QIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARP--LFPST 654 Query: 145 GAVHAAANPFTAAPGAH-GPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFN-SG 202 GA H A+NPF P AH G FL DPF RP++F L +LS+ AFGGLGS G Sbjct: 655 GAAHPASNPF--GPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGG 712 Query: 203 AVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPA---WVRPPEAARTPGSDKERPVERRE 259 ++FA KE SP + W RLHR+P +FPA W + +A R RE Sbjct: 713 SIFAPKEGSSVH-GLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTN----HDRE 767 Query: 260 PSITKEEKDRD-LPFSRPQLRVSPATP------------KARAGEEG-PRPTKESVRVKE 305 P KEE++RD L +R R SPATP ++ G G P + RVKE Sbjct: 768 PDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKE 827 Query: 306 ER---KEEAAAAAAAAAAAAAAAA--------------AAATGPQGLH-------LLFER 341 R KEEAA A A+ + AA A+ GLH L ER Sbjct: 828 SRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRER 887 Query: 342 PRPP-----PFLGPSPPDRC----------AGFLEPTWLAAPPRLARPPRFYEAGEELTG 386 P PF G P R A LEP P R P Y + E L Sbjct: 888 LGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEP---PERPYRDREPHGY-SPERLR- 942 Query: 387 PGAVAAARLYGLEPAHPLLYSRLAPPPP----PAAAPGTPH--LLSKTPP-GALLGAPPP 439 G + AR L PA P L L P P +P H LL++TPP A LGAPPP Sbjct: 943 -GELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPP 1001 Query: 440 LVPA---PRPSSPPR---------GPGPAR 457 LV A P P PPR GPG AR Sbjct: 1002 LVTAAGPPTPPGPPRSRTTPLGGLGPGEAR 1031 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 64.7 bits (156), Expect = 2e-10 Identities = 121/466 (25%), Positives = 152/466 (32%), Gaps = 75/466 (16%) Query: 17 PYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPEL-PPRLGPVPSGLSQKGTQIPDH 75 P + P P P PP+ G + + T P PP P+ S KG P Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990 Query: 76 FRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGA-LPPGQEL 134 PP K G P P P GA PP Sbjct: 991 ATPPSPKGG----------------------------------PATPSPKGAPTPPAVTP 1016 Query: 135 SHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNG--AFG 192 P AT A+ P A P + P SP+ P G PT+ A+ G A Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPS--PKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074 Query: 193 GL-GSPTFNSGAVFAQKESPGAP-------PAFASPPDPWGRL----HRSPLTFPAWVRP 240 L G+PT + + K P P P A+PP P G L H+ T PA P Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134 Query: 241 -PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKA-----RAGEEGP 294 P+ K P P+ T L + P + +P TP A + G P Sbjct: 1135 SPKGGLATPPPKGAPTT---PAATPPSPKGGL--ATPPPKGAPTTPAATPPSPKGGLATP 1189 Query: 295 RPT-KESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFL-GPSP 352 P + + A + A AA P+G L P+ P +P Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAATP 1248 Query: 353 PDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPP 412 P G P AP A P + G L P A + P P +PP Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGG--LATPPHKGAPNPAVVTPPSPKGGPATSPP 1306 Query: 413 P----PPAAAPGTPHLLSKTPPGALLGAP-PPLVPAPRPSSPPRGP 453 PPAA P +P TPP GAP PP V P P P P Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPK--GAPTPPAVTPPSPKGTPTLP 1350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 117/440 (26%), Positives = 138/440 (31%), Gaps = 62/440 (14%) Query: 40 SLQGAFQ-PKSTNPELPP--RLGPVPSG---LSQKGTQIPDHFRP-------PLRKPGKW 86 S QG+ P +T+ PP + P PS LS KG +P P P K G Sbjct: 842 SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901 Query: 87 CAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGA-LPPGQELSHPASLFTATG 145 + + + K + +P P P GA PP P Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKG---IPASPSPKGAPTPPAATPPSPKGGPATPS 958 Query: 146 AVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVF 205 A P P G +PS P G PT AA GG +P+ Sbjct: 959 PKWAPTPPAATPPSPKGGPATPS----PKGAPTP---PAATPPSPKGGPATPS------- 1004 Query: 206 AQKESPGAP-PAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITK 264 GAP P +PP P G +P FP P AA TP S K P P Sbjct: 1005 ----PKGAPTPPAVTPPSPKGSPAATP--FPKGASTPPAA-TPPSPKGSPAATPLPKGAP 1057 Query: 265 EEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAA 324 LP + PATP + P T S + A AA + Sbjct: 1058 TTPAATLPSPKG----GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113 Query: 325 AAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEEL 384 AT P P P PSP G P AP A P + G L Sbjct: 1114 KGGLATPPHK-----GAPTTPAATPPSPK---GGLATPPPKGAPTTPAATPPSPKGG--L 1163 Query: 385 TGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPP---PLV 441 P A P P LA P P A P TP +P G L P P Sbjct: 1164 ATPPPKGAPTTPAATPPSPK--GGLATPSPKGA-PTTPAATPPSPKGGLATPSPKGAPTT 1220 Query: 442 PAPRPSSPPRG---PGPARA 458 PA P SP G P P A Sbjct: 1221 PAATPPSPKGGLATPSPKGA 1240 Score = 57.4 bits (137), Expect = 3e-08 Identities = 111/467 (23%), Positives = 143/467 (30%), Gaps = 62/467 (13%) Query: 19 TAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPEL-PPRLGPVPSGLSQKGTQIPDHFR 77 T P P P PP+ G + + T P PP P+ KG P Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270 Query: 78 PPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGA-LPPGQELSH 136 PP K G H + KG P P GA PP Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGG-----------PATSPPKGAPTPPAATPPS 1319 Query: 137 PASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGS 196 P A P P G P+T G PT+ +S G + Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS----KEGPTPPAAT 1375 Query: 197 PTFNSGAVFAQKESPGAPPAFASP---PDPWGRLHRSPLTFPAWVRPPEAARTPGSDKER 253 P+ G SP PA SP P + SP PA E A TP Sbjct: 1376 PSHKGGPAMTPP-SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434 Query: 254 PVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAA 313 P P++T + S P + PATP ++ P T S + K+ A + Sbjct: 1435 P-----PAVTPVSLKKAPATSAP--KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487 Query: 314 AAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCA-----------GFLEP 362 ++ A A A A T P ++ P+ P S D A L P Sbjct: 1488 SSPKKAPATPAPMGAPTLPA---VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544 Query: 363 TWLAAPPRLARP--------PRFYEA-----GEELTGPGAVAAARLYGLEPAHPLLY--- 406 PP + P P EA +E + P AV + G LL Sbjct: 1545 KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA 1604 Query: 407 ----SRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSP 449 S P PPA P +P TP PP+ P+ SP Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651 Score = 50.4 bits (119), Expect = 3e-06 Identities = 114/480 (23%), Positives = 137/480 (28%), Gaps = 97/480 (20%) Query: 22 PPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSG----LSQKGTQIPDHFR 77 P P P PP+ G A P P P P P G S KG Sbjct: 1145 PKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201 Query: 78 PPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQELSHP 137 PP K G P P GA P + P Sbjct: 1202 PPSPKGGL----------------------------------ATPSPKGA--PTTPAATP 1225 Query: 138 ASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSP 197 S P T A P P+T P G PT AA GGL +P Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATP-PPKGAPTP---PAATPPSLKGGLATP 1281 Query: 198 TFNSG---AVFAQKESPGAP----------PAFASPPDPWGRLHRSP---LTFPAWVRPP 241 AV G P P A+PP P G P P V PP Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341 Query: 242 EAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPA----TPKARAGEEGPR-- 295 TP P + P+ ++ P + P + PA +PK P+ Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401 Query: 296 PTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDR 355 PT +V +K A AA + + L P GP+ P Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461 Query: 356 CAGFLEPTWLAA-PPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPP 414 +PT A PP PP + + A A G P P + P Sbjct: 1462 KG---DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA-PTLPAVI-----PSS 1512 Query: 415 PAAAPGTPH-----------LLSKTPPGALLGAP-----PPLVPAPRPSSPPRGPGPARA 458 P P TP LLSK P L AP PP + P P P P P A Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATL--APKEALIPPAMTVPSPKKTPAIPTPKEA 1570 Score = 45.4 bits (106), Expect = 1e-04 Identities = 118/506 (23%), Positives = 154/506 (30%), Gaps = 103/506 (20%) Query: 22 PPAV-PGLPPGLP--PAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHFRP 78 PPAV P P G P PA + S G P S PP P S KG P Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP-----SHKGGPA---MTP 1386 Query: 79 PLRKPGKWCAMHVRVAYMILRHQEKMKGDSHK---LDFRNDLLPCLPGPY--GALPPGQE 133 P K G KGD + P P A P + Sbjct: 1387 PSPKRGPAIP--------------SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432 Query: 134 LSHPASLFTATGAVHAAANPF--TAAPGAHG-PFLS----PSTHIDPFGRPTSFASLAAL 186 L+ PA + A + P A P + G P L PS P + + +S Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492 Query: 187 SNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHR----------------- 229 + +G+PT + + KE P P + P P L Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552 Query: 230 ----SPLTFPAWVRPPEAARTPGSDKER---------------PVERREPSITKEEKDRD 270 SP PA P EA TP S + P E P ++ Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612 Query: 271 LP----FSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAA 326 P + P PATP + P T S++ A A+ Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672 Query: 327 AAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTG 386 A GP L + P P + P R + + +PP P A G Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP----SAKNGSKG 1728 Query: 387 P-GAVAAARLY-----------GLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKT---PPG 431 P VA A L G + +H LAPP A+ P T K P Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHS-PKGPLAPPESKASTPLTAAAFEKVLPKPES 1787 Query: 432 ALLGAPP------PLVPAPRPSSPPR 451 A + A P PL P+P P+ PP+ Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPPK 1813 Score = 37.7 bits (86), Expect = 0.022 Identities = 81/348 (23%), Positives = 119/348 (34%), Gaps = 45/348 (12%) Query: 128 LPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALS 187 +PP + P A A P ++ + P ++PST+ G P+ L + Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATP-SSKEASSPPAVTPSTYK---GAPSPKELLIPPA 1604 Query: 188 NGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPW---GRLHRSPLTFPAWVRPPEAA 244 + +PT + + ++ P P +P P L SP T PA V A Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP-TSPASVTCKMGA 1663 Query: 245 RTPGSDKERPVERREPSITKEEKDRDLPFSRP----------QLRVSPAT-------PKA 287 P + K P ++ P+ KE P S P Q + S AT P A Sbjct: 1664 TVPQASKGLPA-KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722 Query: 288 RAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLL----FERPR 343 + G +GP T + +K+ + A A+ + A + L FE+ Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782 Query: 344 PPP-----FLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGL 398 P P PSPP LA P PP+ + PG V + L Sbjct: 1783 PKPESASVSAAPSPPVSLP-------LAPSPVPTLPPKQQFLP---SSPGLVLESPSKPL 1832 Query: 399 EPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRP 446 PA L PP P + +L P G P P A +P Sbjct: 1833 APADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880 Score = 35.0 bits (79), Expect = 0.14 Identities = 49/198 (24%), Positives = 73/198 (36%), Gaps = 27/198 (13%) Query: 270 DLPFSRPQLRVSPA-TPKARAGEEGPRPTKESVRV----KEERKEEAAAAAAAAAAAAAA 324 ++P S P + PA TP +G T V KE E++ A+A A++ Sbjct: 729 EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLT 788 Query: 325 AAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEEL 384 A + P G+ + + RPP G + PD G L +P + P L Sbjct: 789 YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP--VSPVEASFLPE-----NSL 841 Query: 385 TGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALL----GAPPPL 440 + G+ + PA + PP P AP + +P G L P + Sbjct: 842 SFQGSKDS-------PA----TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890 Query: 441 VPAPRPSSPPRGPGPARA 458 V P P P P P +A Sbjct: 891 VNLPFPKEGPATPAPKQA 908 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 62.0 bits (149), Expect = 1e-09 Identities = 118/461 (25%), Positives = 148/461 (32%), Gaps = 85/461 (18%) Query: 16 NPYTAFPPAVPGL----PPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQ 71 +P T PP P PP PPA++ LQG P + PP P Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP----------- 622 Query: 72 IPDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPG 131 P PPL+ P P P A PP Sbjct: 623 -PXLALPPLQAP--------------------------------------PSP-PASPPL 642 Query: 132 QELSHPASLFTATGAVHAAANPFT--AAPGAHGPFLSP-STHIDPFGRPTSFA--SLAA- 185 L+ P+ AVH PF+ +P PF P S + P P S A SLAA Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702 Query: 186 -LSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAA 244 L P S Q P A P PP P SP P PP A Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA 762 Query: 245 RTPGSDKERPVERREPS-ITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRV 303 P P S + K + P L+ P+ P + G + P S+ + Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG-QAPFSPSASLPM 821 Query: 304 KEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPP---DRCAGFL 360 A AA + P + PR PP GP R L Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASP-----TLQAPRRPPTPGPDTSVSGPRLTLAL 876 Query: 361 EPTWLAAPPRLARPPRFYEAGEELTGPGAVAAA---RLYGLEPAHPLLYSRLAPPPPPAA 417 P PP +R P +G +L G + A + L G + + P + +PPP Sbjct: 877 AP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPEGGAAASPPPDAEL 932 Query: 418 APGTPHLLSK--TPPGALLGAPPPLVPAPRPSSPPRGPGPA 456 A P S+ PP A GAP AP P P GPG A Sbjct: 933 AACHPAAWSRGPAPPLAFRGAP----GAPLPWPPATGPGSA 969 Score = 60.8 bits (146), Expect = 2e-09 Identities = 116/478 (24%), Positives = 163/478 (34%), Gaps = 59/478 (12%) Query: 16 NPYTAFPPAVPGLPP---GLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQI 72 N T P +P PP LP A S + Q + P PP P ++ Q Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP--SQAPPSMTTPPMQA 379 Query: 73 PDHFR--PPLRKPGKWCAMHVRVA---YMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGA 127 P + PP++ P + ++ + Q S L + L P A Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439 Query: 128 --LPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAA 185 P + S P + A+P LSP+ + P P + L A Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS------LSPA--VSPLSSPLTIHPLQA 491 Query: 186 LSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPP---------------DPWGRLHRS 230 LS+ A +P + + +S APP+ +PP P + + Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551 Query: 231 PLTFPAWVRPPEAA----RTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPK 286 PLT P PP A + P S P SI + P L+ P+ P Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611 Query: 287 ARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLL----FERP 342 + P P + + A+ + A + A +HLL P Sbjct: 612 SPLAT--PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669 Query: 343 RPP---PFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLE 399 PP PF P+ P P+ APP LA PP + P + +A Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPS--QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727 Query: 400 PAHPLLYSRL-APPPPPAAAPGTPHLLSKTPP---GALLGAPPPLVPAPRPSSPPRGP 453 P PL L PP PPA+ P +P S TPP LL APP VP P+S P P Sbjct: 728 P--PLAAPPLQVPPSPPASPPMSP---SATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780 Score = 52.4 bits (124), Expect = 9e-07 Identities = 114/466 (24%), Positives = 161/466 (34%), Gaps = 76/466 (16%) Query: 32 LPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHFRPPLRKPGKWCAMHV 91 + P + SL +P ST P+ PP P+ S PL P Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP-------- 483 Query: 92 RVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFT--------- 142 + L+ + S + + ++P L PP + + PASL T Sbjct: 484 -LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ-TPPASLTTPPLENLPSL 541 Query: 143 ATGAVHAAANPFTAAP------GAHGPFLSPSTHID--PFGRPTSFASLA-----ALSNG 189 A + A+ P T A P +P + + P P+S A+ AL++ Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601 Query: 190 AFGGLGSPTFNSGAVFAQKESPG-APPAFASPPDPWGRLHRSPLTFPAWVRPPEAA---- 244 GL SP + A + P A P +PP P SPL P+ P A Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661 Query: 245 RTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVK 304 + P S P + PFS P P +P A + P P+ + ++ Sbjct: 662 QAPFSPPPSPPVQA-------------PFSPPAS--PPVSPSATPPSQAP-PSLAAPPLQ 705 Query: 305 EERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTW 364 A+ + +A A P + P PP P P P Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPP-----LQVPPSPPASPPMSPSATPPPRVPPL 760 Query: 365 LAAPPRLARP------PRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAA 418 LAAPP P P A P A+A L L P+ P + AP P A+ Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL-PSPPASFPGQAPFSPSASL 819 Query: 419 PGTPHLLSKTPPGA--LLGAPPPLVPAPRPSSP-------PRGPGP 455 P +P L+ PP A +L AP VP P+SP P PGP Sbjct: 820 PMSP--LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863 Score = 42.0 bits (97), Expect = 0.001 Identities = 78/298 (26%), Positives = 104/298 (34%), Gaps = 60/298 (20%) Query: 175 GRPTSFASLAALSNGAFGGLGSPTFN--SGAVFAQKESPG--------APPAFASPPDPW 224 G+ T +ALS GA PT S A+ + + G AP A PP Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204 Query: 225 GRLHRSPLTFPAWVRPPEAAR---TPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVS 281 R S + + P AAR + G +RP R S P S P R Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT-------PLSSPA-RSG 256 Query: 282 PA---TPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLL 338 P+ TP+A A P+P K ++ + AA A +++ A P G Sbjct: 257 PSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT--- 312 Query: 339 FERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGL 398 + RP P PPD A L T +PP P L P Sbjct: 313 --KARPVP-----PPDNAATPLPATLPPSPPLATPLP--------LAPPS---------- 347 Query: 399 EPAHPLLYSRLAPPP--PPAAAPGTPHLLSKTPPGALLGAPPPLVP----APRPSSPP 450 P+ P L PP PP+ AP + P +L PP VP +P +PP Sbjct: 348 -PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404 Score = 30.0 bits (66), Expect = 4.6 Identities = 41/144 (28%), Positives = 52/144 (36%), Gaps = 31/144 (21%) Query: 305 EERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSP------------ 352 + ++++A A AAA AA A P G PRPPP + P+ Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGR 55 Query: 353 ---PDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRL 409 +R G T + PR A P R AG P + A G E A P + Sbjct: 56 KPLAERAGGIGGATIPESAPR-AGPTR--SAGTSSRNPASRPPASGRG-ERAPPAKNTSP 111 Query: 410 APPPPPAAAPGTPHLLSKTPPGAL 433 P P A GT T PG L Sbjct: 112 GPVSSPGRASGT------TRPGPL 129 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 61.2 bits (147), Expect = 2e-09 Identities = 68/208 (32%), Positives = 82/208 (39%), Gaps = 42/208 (20%) Query: 253 RPVERR---EPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKE 309 R V RR EP T+ E ++ L R LRVS +G + + RV+ R+ Sbjct: 56 RMVRRRHGPEPERTRAELEK-LIQQRAVLRVS---------YKGSISYRNAARVQPPRRG 105 Query: 310 EAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPP 369 A A A AAAAAA P P PPP P+P A P AA Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPP-------TPAPPP--PPAPVAAAAPARAPR--AAAA 154 Query: 370 RLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGT--PHLLSK 427 PP G GP A AA L APPP PAA P P + Sbjct: 155 AATAPP---SPGPAQPGPRAQRAAPL-------------AAPPPAPAAPPAVAPPAGPRR 198 Query: 428 TPPGALLGAPPPLVPAPRPSSPPRGPGP 455 PP A+ PPL P P+P +PP+ P Sbjct: 199 APPPAVAAREPPLPPPPQPPAPPQQQQP 226 Score = 45.4 bits (106), Expect = 1e-04 Identities = 44/138 (31%), Positives = 46/138 (33%), Gaps = 13/138 (9%) Query: 282 PATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFER 341 PA P+A G A AAAA A A AAAAAAT P Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP--------- 159 Query: 342 PRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPA 401 P P P R A P A P PP AG P AVAA P Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPP----AGPRRAPPPAVAAREPPLPPPP 215 Query: 402 HPLLYSRLAPPPPPAAAP 419 P + PPPP P Sbjct: 216 QPPAPPQQQQPPPPQPQP 233 Score = 39.3 bits (90), Expect = 0.008 Identities = 20/54 (37%), Positives = 23/54 (42%) Query: 407 SRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR 460 +R+ PP A P P P A APPP P P +P PARA R Sbjct: 97 ARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPR 150 Score = 35.0 bits (79), Expect = 0.14 Identities = 66/247 (26%), Positives = 79/247 (31%), Gaps = 40/247 (16%) Query: 206 AQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKE 265 A + +P A A A PP P +P+ A R P AA + P P+ Sbjct: 114 APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP----GPAQPGP 169 Query: 266 EKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAA 325 R P + P +PA P A A GPR A A AA Sbjct: 170 RAQRAAPLAAPP--PAPAAPPAVAPPAGPR-------------------RAPPPAVAARE 208 Query: 326 AAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELT 385 PQ ++ PPP P PP G + A P L R Y G Sbjct: 209 PPLPPPPQPPAPPQQQQPPPP--QPQPPPE-GGAVRAGGAARPVSLREVVR-YLGGSGGA 264 Query: 386 GPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPR 445 G G + R+ GL RL A A P G G PP A R Sbjct: 265 G-GRLTRGRVQGLLEEEAAARGRLERTRLGALA---------LPRGDRPGRAPPAASA-R 313 Query: 446 PSSPPRG 452 PS RG Sbjct: 314 PSRSKRG 320 Score = 31.6 bits (70), Expect = 1.6 Identities = 29/94 (30%), Positives = 33/94 (35%), Gaps = 35/94 (37%) Query: 366 AAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLL 425 A PP R PR P A AAA APPP PA P Sbjct: 106 ATPPAPPRAPR--------GAPAAAAAA----------------APPPTPAPPP------ 135 Query: 426 SKTPPGALLGAPPPLVP--APRPSSPPRGPGPAR 457 PP + A P P A ++ P PGPA+ Sbjct: 136 ---PPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166 Score = 30.0 bits (66), Expect = 4.6 Identities = 58/232 (25%), Positives = 81/232 (34%), Gaps = 26/232 (11%) Query: 129 PPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSN 188 PP + + PA GA AAA A P +P P P + A+ A Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160 Query: 189 GAFGGLGSPTFNSGA-VFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTP 247 P A + A +P APPA A P P R+P P V E P Sbjct: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP----RRAP---PPAVAAREPPLPP 213 Query: 248 GSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPK------ARAGEEGPRPTKESV 301 P ++++P + + + R P + + +G G R T+ Sbjct: 214 PPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRG-- 271 Query: 302 RVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERP-RPPPFLGPSP 352 RV+ +EEAAA A A P+G +RP R PP P Sbjct: 272 RVQGLLEEEAAARGRLERTRLGALAL----PRG-----DRPGRAPPAASARP 314 Score = 30.0 bits (66), Expect = 4.6 Identities = 18/48 (37%), Positives = 21/48 (43%) Query: 17 PYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSG 64 P A PPAV P LPP + QP P+ PP G V +G Sbjct: 196 PRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAG 243 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 60.5 bits (145), Expect = 3e-09 Identities = 89/331 (26%), Positives = 112/331 (33%), Gaps = 58/331 (17%) Query: 156 AAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPP 215 AA AH L+P T A+ AL N G + +G + +PGA P Sbjct: 34 AASAAHHHHLAPRTP------EVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87 Query: 216 AFASPPDPWGRLH--------------RSPLTFPAWVRPPEAARTPGSDKERPVERREPS 261 P P GR R PL PA PP A P + P+ Sbjct: 88 E----PPPAGRARPGGGGPQRPGPPSPRRPLV-PAGPAPPAAKLRPPPEGSAGSCAPVPA 142 Query: 262 ITKEEKDRDLPFSRPQLRVSPATPKARAGE---------EGPRPTKESVRVKEERKEEAA 312 + + P PA ARAG GP P K + + +A Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSA 202 Query: 313 AAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLA 372 A + AAA A + GP L L +P P + +PP A AAPP A Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAAL-LPLPKPAAPGTVIQTPPFVGA--------AAPPAPA 253 Query: 373 RPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPP-----PPAAAPGTPHLLSK 427 P + P A A A P P + LA PP PP AAP P + Sbjct: 254 AP----------SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAA 303 Query: 428 TPPGALLGAPPPLVPAPRPSSPPRGPGPARA 458 G+ AP P A P+ PGP A Sbjct: 304 QNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334 Score = 51.6 bits (122), Expect = 1e-06 Identities = 97/367 (26%), Positives = 122/367 (33%), Gaps = 76/367 (20%) Query: 124 PYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASL 183 P G PP +L P G+ + A AA A GP +P+ P G P + A+ Sbjct: 116 PAGPAPPAAKLRPPPE-----GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-PAALAAR 169 Query: 184 AALSNGAFGGLG-------------SPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRS 230 A G G G + T N A AP P L Sbjct: 170 AGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL--- 226 Query: 231 PLTFPAWVRPPEAARTP----GSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPK 286 PL PA P +TP + P P+ P P + A P Sbjct: 227 PLPKPA--APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284 Query: 287 ARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPP 346 GP +V AAA +A AA A A AA GP G+ +P P Sbjct: 285 GHPA--GPPTAAPAV------PPPAAAQNGGSAGAAPAPAPAAGGPAGVS---GQPGPGA 333 Query: 347 FLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEEL--TGPGAVAAARLYGLEPAHPL 404 P A + AAPP A + L +GP + AA+ + G P Sbjct: 334 AAAAPAPGVKAESPKRVVQAAPP----------AAQTLAASGPASTAASMVIG-----PT 378 Query: 405 LYSRLAPP---PPPAAAPGTP------------HLLSKTPPGALLGAPPPLVP---APRP 446 + L P PPPA PGTP LS+TP G L P APR Sbjct: 379 MQGALPSPAAVPPPA--PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRL 436 Query: 447 SSPPRGP 453 PP+ P Sbjct: 437 PQPPQNP 443 Score = 38.5 bits (88), Expect = 0.013 Identities = 45/157 (28%), Positives = 58/157 (36%), Gaps = 32/157 (20%) Query: 310 EAAAAAAAA-----AAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTW 364 E+ AA+AA A AAA G G H++ P GP+ P Sbjct: 30 ESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE--------- 80 Query: 365 LAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPP-----PPPAAAP 419 AP PP AG PG R P PL+ + APP PPP + Sbjct: 81 -GAPGAAPEPP---PAGR--ARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSA 134 Query: 420 GTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPA 456 G+ + P A + A P P P+ P + GPA Sbjct: 135 GS---CAPVPAAAAVAAG----PEPAPAGPAKPAGPA 164 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 59.3 bits (142), Expect = 7e-09 Identities = 72/279 (25%), Positives = 98/279 (35%), Gaps = 44/279 (15%) Query: 156 AAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPG--- 212 A+PG +PS P GR TS + G P + PG Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP---------QPGPGPQR 476 Query: 213 -APPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDL 271 PP PP P G+ H S L PA P+ +P S ++P + P + + Sbjct: 477 QGPPLQQRPP-PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQ--- 532 Query: 272 PFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATG 331 SRP + P P A P P +++ + R+ + A A+ A G Sbjct: 533 --SRP-VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQG 589 Query: 332 PQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVA 391 P P+ PP GP+ P R A P PP +P +GPG Sbjct: 590 P---------PQKPP--GPAGPTRQASQAGPVPRTGPPTTQQP--------RPSGPGPAG 630 Query: 392 AARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPP 430 + P S+ PPP AAA G PH K P Sbjct: 631 RPK-----PQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664 Score = 36.2 bits (82), Expect = 0.064 Identities = 38/120 (31%), Positives = 46/120 (38%), Gaps = 16/120 (13%) Query: 343 RPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAH 402 RPPP GP P PP RPP + + L+G G A + P Sbjct: 460 RPPPQGGPPQPG------PGPQRQGPPLQQRPPP--QGQQHLSGLGPPAGS------PLP 505 Query: 403 PLLYSRLAPPPPPA--AAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR 460 L S + P PA AAP T ++ P A PP P SP R GP +A R Sbjct: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATR 565 Score = 35.8 bits (81), Expect = 0.084 Identities = 44/179 (24%), Positives = 60/179 (33%), Gaps = 19/179 (10%) Query: 285 PKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRP 344 P+ + GP P ++ +++ + + A + PQ L P+ Sbjct: 463 PQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPL-----PQRLPSPTSAPQQ 517 Query: 345 PPFLGPSPPDRCAGFLEPTWLAAP--PRLARPPRFYEAGEELTGPGAVAAARLYGLEP-- 400 P +PP + G P P ARPP + P A + G P Sbjct: 518 PASQA-APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576 Query: 401 ---AHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPA 456 A P R PP P G S+ P G PP PRPS GPGPA Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG--PPTTQQPRPS----GPGPA 629 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 58.9 bits (141), Expect = 9e-09 Identities = 95/337 (28%), Positives = 124/337 (36%), Gaps = 76/337 (22%) Query: 175 GRPTSFASLAALSNGAFGGLGSPTFN--SGAVFAQKESPG--------APPAFASPPDPW 224 G+ T +ALS GA PT S A+ + + G AP A PP Sbjct: 136 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 195 Query: 225 GRLHRSPLTFPAWVRPPEAAR---TPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVS 281 R S + + P AAR + G +RP R S P S P R Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT-------PLSSPA-RSG 247 Query: 282 PA---TPKARAGEEGPRP----TKESVRVKEERKEEAAA----AAAAAAAAAAAAAAAAT 330 P+ TP+A A P+P +V RK+ A A +++ A + +A + + Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307 Query: 331 GPQGLHLLFERPRPPPF-----LG-----------PSPPDRCAGFLEPTWLAAPPRLARP 374 P L L P PP LG PSPP P APP LA P Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ---APPALALP 364 Query: 375 PRFYEAGEELTGPGAVAAARLYGLEPAHP------LLYSRLAPPP---------PPAAAP 419 P + P + + L P P LL + +PPP PPA+ P Sbjct: 365 P----LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420 Query: 420 GTPHLLSKTPPGAL---LGAPPPLVPAPRPSSPPRGP 453 +P S TPP L APP VP P+SPP P Sbjct: 421 VSP---SATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454 Score = 54.3 bits (129), Expect = 2e-07 Identities = 115/451 (25%), Positives = 150/451 (33%), Gaps = 93/451 (20%) Query: 22 PPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP-VPSGLSQKGTQIPDHFRPPL 80 P P P P S+ A + +T P R P GL + ++ PL Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 Query: 81 RKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYG--ALPPGQELSHPA 138 P + G S + R P P P G AL P Q Sbjct: 241 SSPAR-------------------SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281 Query: 139 SLFTATGAVHAA--ANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGS 196 A G + ++ A P +AP + S T P P S A+ + LGS Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS---------LGS 332 Query: 197 PTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVE 256 PT + F SP P PP L PL P P A P S Sbjct: 333 PTLQATHSFLP--SPPLSPLATPPPQAPPALALPPLQAP----PSPPASPPLS------- 379 Query: 257 RREPSITKEEKDRDLPFSRPQLRVSPATPKARAGE--EGPRPTKESVRVKEERKEEAAAA 314 P + P SP P A A + P S V+ A+ Sbjct: 380 ---------------PLATP----SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420 Query: 315 AAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPP-RLAR 373 + +A + A + P + P PP P P P LAAPP +LA+ Sbjct: 421 VSPSATPPSQAPPSLAAPP-----LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475 Query: 374 PPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGA- 432 PP P A+A L L P+ P + AP P A+ P +P L+ PP A Sbjct: 476 PPP--------QAPPALATPPLQAL-PSPPASFPGQAPFSPSASLPMSP--LATPPPQAP 524 Query: 433 -LLGAPPPLVPAPRPSSP-------PRGPGP 455 +L AP VP P+SP P PGP Sbjct: 525 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555 Score = 50.8 bits (120), Expect = 3e-06 Identities = 90/342 (26%), Positives = 117/342 (34%), Gaps = 48/342 (14%) Query: 124 PYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASL 183 P ALPP Q P A+ + A P AP A L + PF P S Sbjct: 359 PALALPPLQAPPSPP----ASPPLSPLATPSPQAPNALAVHLLQA----PFSPPPSPPVQ 410 Query: 184 AALSNGAFGGLGSPTFNSGAVFAQKESPG-APPAFASPPDPWGRLHRSPLTFPAWVRPPE 242 A S A SP + A + P A P PP P SP P PP Sbjct: 411 APFSPPA-----SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465 Query: 243 AARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVR 302 A P +P + P++ + P L+ P+ P + G+ P S+ Sbjct: 466 LAAPP-LQLAKPPPQAPPAL-----------ATPPLQALPSPPASFPGQ-APFSPSASLP 512 Query: 303 VKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPP---DRCAGF 359 + A AA + P + PR PP GP R Sbjct: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPT-----LQAPRRPPTPGPDTSVSGPRLTLA 567 Query: 360 LEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAA---RLYGLEPAHPLLYSRLAPPPPPA 416 L P PP +R P +G +L G + A + L G + P + +PPP Sbjct: 568 LAP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASPPPDAE 623 Query: 417 AAPGTPHLLSK--TPPGALLGAPPPLVPAPRPSSPPRGPGPA 456 A P S+ PP A GAP AP P P GPG A Sbjct: 624 LAACHPAAWSRGPAPPLAFRGAP----GAPLPWPPATGPGSA 661 Score = 50.1 bits (118), Expect = 4e-06 Identities = 116/479 (24%), Positives = 154/479 (32%), Gaps = 69/479 (14%) Query: 19 TAFPPAVPGLPPGLPPA-VSFGSLQGAFQPK-----------STNPELPPRLGPV----- 61 T PP P PP + PA + GA K +T PE PR GP Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 Query: 62 -PSGLSQKGTQIPDHFRPPLRKPGKWCAMHV-----RVAYMILRHQEKMKGDSHKLDFRN 115 SG ++ + P+ PG+ + I + +G + + R+ Sbjct: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 Query: 116 DLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAA---PGAHGPFLSPSTHID 172 L PG A A G P +A P GP S S+ + Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 Query: 173 PFGRPTSFASLAALSNGAFGGLGSP---TFNSGAVFAQKESPGAPPAFASPPDPWGRLHR 229 S A+ S G GGL P + +S A + P A +P P Sbjct: 206 HSTTEPSPAARRRPSAG--GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 263 Query: 230 SPLTFPAWVRPPE-------AARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSP 282 P A +RPP+ AA G P+ PS P S L P Sbjct: 264 KPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS---APPSLQTLPSPP 319 Query: 283 ATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERP 342 ATP ++A PT ++ + A A A A P P Sbjct: 320 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP---------P 370 Query: 343 RPP------PFLGPSP--PDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAAR 394 PP P PSP P+ A L + PP F P A ++ Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430 Query: 395 LYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGAL---LGAPPPLVPAPRPSSPP 450 A PL PP PPA+ P +P S TPP L APP + P P +PP Sbjct: 431 APPSLAAPPLQ----VPPSPPASPPMSP---SATPPPQAPPPLAAPPLQLAKPPPQAPP 482 Score = 30.4 bits (67), Expect = 3.5 Identities = 53/203 (26%), Positives = 67/203 (33%), Gaps = 62/203 (30%) Query: 305 EERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSP------------ 352 + ++++A A AAA AA A P G PRPPP + P+ Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGR 55 Query: 353 ---PDRCAG-----FLEPTWLAAPPRLARPPRFYEAGEEL-----TGPGAVAA-ARLYGL 398 +R G E A P R +RPP GE T PG V++ R G Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPA-SGRGERAPPAKNTSPGPVSSPGRASGT 114 Query: 399 EPAHPLLYSRL------------APPPPPAAA-------------PGTPH---LLSKTPP 430 PL L A P +A PGTP Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174 Query: 431 GALLGAPPPLVPAPRPSSPPRGP 453 G +G P P P+ RP P GP Sbjct: 175 GTEVGLPRP-APSARPRPPTEGP 196 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 58.2 bits (139), Expect = 2e-08 Identities = 75/296 (25%), Positives = 101/296 (34%), Gaps = 44/296 (14%) Query: 156 AAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPG--- 212 A+PG +PS P GR TS + G P + PG Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP---------QPGPGPQR 476 Query: 213 -APPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDL 271 PP PP P G+ H S L PA P+ +P S ++P + P + + Sbjct: 477 QGPPLQQRPP-PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQ--- 532 Query: 272 PFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATG 331 SRP + P P A P P +++ + R+ + A A+ A G Sbjct: 533 --SRP-VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQG 589 Query: 332 PQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVA 391 P P+ PP GP+ P R A P PP +P +GPG Sbjct: 590 P---------PQKPP--GPAGPTRQASQAGPVPRTGPPTTQQP--------RPSGPGPAG 630 Query: 392 AARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPS 447 + P S+ PPP AAA G PH P PRPS Sbjct: 631 RPK-----PQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPS 681 Score = 36.2 bits (82), Expect = 0.064 Identities = 38/120 (31%), Positives = 46/120 (38%), Gaps = 16/120 (13%) Query: 343 RPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAH 402 RPPP GP P PP RPP + + L+G G A + P Sbjct: 460 RPPPQGGPPQPG------PGPQRQGPPLQQRPPP--QGQQHLSGLGPPAGS------PLP 505 Query: 403 PLLYSRLAPPPPPA--AAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR 460 L S + P PA AAP T ++ P A PP P SP R GP +A R Sbjct: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATR 565 Score = 35.8 bits (81), Expect = 0.084 Identities = 44/179 (24%), Positives = 60/179 (33%), Gaps = 19/179 (10%) Query: 285 PKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRP 344 P+ + GP P ++ +++ + + A + PQ L P+ Sbjct: 463 PQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPL-----PQRLPSPTSAPQQ 517 Query: 345 PPFLGPSPPDRCAGFLEPTWLAAP--PRLARPPRFYEAGEELTGPGAVAAARLYGLEP-- 400 P +PP + G P P ARPP + P A + G P Sbjct: 518 PASQA-APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576 Query: 401 ---AHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPA 456 A P R PP P G S+ P G PP PRPS GPGPA Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG--PPTTQQPRPS----GPGPA 629 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 58.2 bits (139), Expect = 2e-08 Identities = 68/272 (25%), Positives = 90/272 (33%), Gaps = 29/272 (10%) Query: 207 QKESPGAPPAFASPPDPWGRLHRSPLTFPAWVR-----PPEAARTPGSDKER-------- 253 QKE+ SP P R RSP P R PP RTP R Sbjct: 537 QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRY 596 Query: 254 --PVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEA 311 P++RR ++ P P+ R SP+ P R P P + S V + R Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656 Query: 312 AAA-AAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPR 370 ++ ++ + + A + P H RPR P PP R P +P Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSP 716 Query: 371 LARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPP 430 RP R E P + A + + SR P AA P PP Sbjct: 717 STRPIRRVSRTPE---PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP-----APP 768 Query: 431 GALLGAPP-----PLVPAPRPSSPPRGPGPAR 457 + P P VP + SP P P R Sbjct: 769 SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800 Score = 38.9 bits (89), Expect = 0.010 Identities = 54/233 (23%), Positives = 84/233 (36%), Gaps = 38/233 (16%) Query: 129 PPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSN 188 PP + +SH + V +P ++ G S ST +P S + Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689 Query: 189 GAFGGLGSPTFNSGAVFA----QKESPGAPPA--FASPPDPWGRLHRSPLTFPAWVRPPE 242 P GA + Q SP P + P+P ++ ++ P VR Sbjct: 690 APQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP-KKIKKAASPSPQSVRRVS 748 Query: 243 AARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPT----- 297 ++R+ E P ++ P+ + + P SPA P +A P P+ Sbjct: 749 SSRSVSGSPE-PAAKKPPAPPSPVQSQS-----PSTNWSPAVPVKKAKSPTPSPSPPRNS 802 Query: 298 --------------------KESVRVKEERKEEAAAAAAAAAAAAAAAAAAAT 330 K+ + K+ +KE+A AAAAAAA AA AAA T Sbjct: 803 DQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATT 855 Score = 37.4 bits (85), Expect = 0.029 Identities = 59/270 (21%), Positives = 88/270 (32%), Gaps = 65/270 (24%) Query: 242 EAARTPGSDKER-PVERREPSITKEEKDRDLPFS-RPQLRVSPATPKARAGEEGPRPTKE 299 E +R+P K R P RR S + E+ R S R + + +P E+ P + Sbjct: 167 ERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEP 226 Query: 300 SVRVKEERKEEAAAAA---------------------------------------AAAAA 320 SV+VKE +EA + + + + + Sbjct: 227 SVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286 Query: 321 AAAAAAAAATGPQGLH-----LLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPP 375 + + + T P+ H R RP P PSP R PPR PP Sbjct: 287 RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR-----------TPPRRMPPP 335 Query: 376 RFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLG 435 + ++A L G + SR P PP P + P A Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA--- 392 Query: 436 APP-----PLVPAPRPSSPPRGPGPARADR 460 +PP P PA P P P +++R Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422 Score = 34.7 bits (78), Expect = 0.19 Identities = 60/277 (21%), Positives = 83/277 (29%), Gaps = 21/277 (7%) Query: 196 SPTFNSGAVFAQKESPGAPPA-FASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERP 254 S + +S + + P PP +SPP RL S RP A P + P Sbjct: 356 SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415 Query: 255 VERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERK--EEAA 312 ++ K + ++ T K + P+P K + EE K + AA Sbjct: 416 TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAA 475 Query: 313 AAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLA 372 A + ++ G E RP + P+ A+P Sbjct: 476 ADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK 535 Query: 373 RPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTP---------- 422 R G P R PA P R PPP P P Sbjct: 536 RQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR 595 Query: 423 ------HLLSKTPPGALLGAPPPLVPAPR--PSSPPR 451 S +PP A PP P R PS PP+ Sbjct: 596 YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632 Score = 30.0 bits (66), Expect = 4.6 Identities = 35/158 (22%), Positives = 59/158 (37%), Gaps = 34/158 (21%) Query: 240 PPEAARTPGSDKERPVERREPSITKEEKDRDLPFSR-------------------PQLRV 280 P E + S KE+ E+ P K R SR P+ R Sbjct: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP 315 Query: 281 SP---ATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHL 337 SP +P+ R P R + + ++A+ + ++++++++ + P Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP----- 370 Query: 338 LFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPP 375 P+ PP SPP R L P+ A+PPR P Sbjct: 371 ----PKKPPKRTSSPP-RKTRRLSPS--ASPPRRRHRP 401 Score = 30.0 bits (66), Expect = 4.6 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 11/114 (9%) Query: 240 PPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKE 299 P AA+ P + PV+ + PS +P + + +P + +EG K+ Sbjct: 757 PEPAAKKPPAPPS-PVQSQSPSTNWSPA---VPVKKAKSPTPSPSPPRNSDQEGGGKKKK 812 Query: 300 SVRVKEERKEEA-------AAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPP 346 + K+ +K++ A AAAAAAA AA L E P P Sbjct: 813 KKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAP 866 >gi|154146199 sal-like 3 [Homo sapiens] Length = 1300 Score = 57.8 bits (138), Expect = 2e-08 Identities = 76/295 (25%), Positives = 104/295 (35%), Gaps = 56/295 (18%) Query: 204 VFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSD----KERPVERR- 258 + +++P PP P+P SP + P+ EAA G++ + RPVE+ Sbjct: 80 LIVHEDAPAPPPE--DFPEP------SPASSPSERAESEAAEEAGAEGAEGEARPVEKEA 131 Query: 259 EPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKE---SVRVKEERKEEAAAAA 315 EP + D P P +PA P G T E S +V + + A AA Sbjct: 132 EPMDAEPAGDTRAPRPPP---AAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAA 188 Query: 316 AAAAAAAAAAAAA---------ATGPQGLH------------LLFERPRPPPFLGPSP-- 352 + A AAAA A Q +H L +RP P P L P+ Sbjct: 189 GGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAP 248 Query: 353 ------PDRCAGFLEPTWLAAPPRLA------RPPRFYEAGEELTGPGAVAAARLYGLEP 400 P + G A P A P +E + L+ P + A+ EP Sbjct: 249 SAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEP 308 Query: 401 AHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGP 455 + P S P PA AP S P A PP L P + P P P Sbjct: 309 SAPAAPSAAPAPAAPAPAPAPQSAASSQPQSA--STPPALAPGSLLGAAPGLPSP 361 Score = 32.7 bits (73), Expect = 0.71 Identities = 54/199 (27%), Positives = 71/199 (35%), Gaps = 26/199 (13%) Query: 281 SPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFE 340 +PA P E P + S R + E EEA A A A A + Sbjct: 86 APAPPPEDFPEPSPA-SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDT-R 143 Query: 341 RPRPPPFLGPSPPDRCAGF--LEPTWLAAPPRLARPPRFYEAGEELTGPGA---VAAA-- 393 PRPPP P+PP G T A +F + G GA VAAA Sbjct: 144 APRPPP-AAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAV 202 Query: 394 -----RLYGLEPA--HPL-----LYSRLA----PPPPPAAAPGTPHLLSKTPPGALLGAP 437 +L L+ H L + S++A PPP P+ +P P L G Sbjct: 203 PLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLA 262 Query: 438 PPLVPAPRPSSPPRGPGPA 456 + A P++ G GPA Sbjct: 263 ALPLSAGAPAAAIAGSGPA 281 >gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo sapiens] Length = 636 Score = 55.8 bits (133), Expect = 8e-08 Identities = 101/375 (26%), Positives = 122/375 (32%), Gaps = 57/375 (15%) Query: 122 PGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTS-F 180 P G LP P LF A G + F P A F P P R T F Sbjct: 120 PRRRGFLPAAGFCPPPPRLFVAAGFLPPRPRGFF--PPADAAFCPPRLFATPRPRATRLF 177 Query: 181 ASLAAL-SNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLT------ 233 A AAL + F + F + PP + P HR LT Sbjct: 178 APAAALFARPGFLPPAAAAFCRRGFLHPRRHGFFPPRLFARPGFLPPSHRGLLTPRRRGF 237 Query: 234 -----FPAWVRPPEAARTPGSDKERPVERR---EPSITKEEKDRDLPFSRPQLR------ 279 ++ PP A P R +P+ + LP +RP Sbjct: 238 LPPPRHRGFLPPPATAAFSPPRLFTPCRRGFLLDPAFCSSHRRGFLPPTRPGAADICPSR 297 Query: 280 -VSPATPKARAGEEGPRP---TKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGL 335 +P +P+ PRP + V R+ AAAAAAAAAAAAAAA L Sbjct: 298 LFAPPSPRLF-----PRPGFLPRRRRGVLAHRRRGVLLPAAAAAAAAAAAAAAAAAAFCL 352 Query: 336 HLLFERPRPPPFLGPSPP----DRCAGFLEPTWLAAPPRLAR-------------PPRFY 378 LF P F P P GFL P P R PPR + Sbjct: 353 TQLFAPPTAAAFCPPPAPVPRLFARRGFLHPRRRGFLPLFRRGFLPLFRRGFFPAPPRLF 412 Query: 379 EAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPP 438 P RL+ P + PPPP AAA L P PP Sbjct: 413 ILRRRGFLPPPPPPPRLFARLGFLPPAAAAFCPPPPAAAA----FCLRGFLPDPAFSPPP 468 Query: 439 PLV---PAPRPSSPP 450 P + PAPR +PP Sbjct: 469 PRLFAPPAPRLFAPP 483 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 55.5 bits (132), Expect = 1e-07 Identities = 102/398 (25%), Positives = 130/398 (32%), Gaps = 97/398 (24%) Query: 124 PYGAL--------PPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFG 175 P+GA+ PP + ++ F T A A P A P+ +P H P Sbjct: 353 PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPP-AQATPAPGFKSAFSPYQTPVAHFPPPP 411 Query: 176 R-PTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTF 234 PT+ A+ A +G F +P A KE PG PP PPD TF Sbjct: 412 EEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPG-PPPPDTNSMELGGRPTF 470 Query: 235 PAWVRPPEAARTPG--------SDKERPVER-------------------REPSITKEEK 267 W PE +PG + E+P + REP E + Sbjct: 471 -GW--SPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQ 527 Query: 268 DRDLPFSRPQLRVSPATPKARAGEEGPR-PTKESVRVKEERKEEAAAAAAAAAAAAAAAA 326 P S ++SP P + G R PT S R E+ + + Sbjct: 528 MEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELD 587 Query: 327 AAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLA-RPP--RFYEAGEE 383 L PRPPP GP P AG L T A + R P + G++ Sbjct: 588 -----------LGLGPRPPPEPGPPDP---AGLLSQTAEVALDLVGDRTPTSEKMDEGQQ 633 Query: 384 LTG---------------------------PGAVAAARLYGLEPAHPLLYSRLAPPPPPA 416 +G PGA A A L P PL PPPP Sbjct: 634 SSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPL-------PPPPG 686 Query: 417 AAPGTPHLLSKTPPGALLGAP-PPLVPAPRPSSPPRGP 453 P P PP G P PP +P P P PP P Sbjct: 687 FPPLPP---PPPPPPPQPGFPMPPPLPPPPPPPPPAHP 721 Score = 37.4 bits (85), Expect = 0.029 Identities = 60/239 (25%), Positives = 80/239 (33%), Gaps = 46/239 (19%) Query: 250 DKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARA---------------GEEGP 294 D++ E + E ++D S + VS T KA A E P Sbjct: 1070 DRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSP 1129 Query: 295 RPTK--ESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSP 352 ++ E V +EE +EE A + A+A GP+ FE+ L P Sbjct: 1130 SSSEDEEEVVAREEEEEEEEEEMVAEESMASA------GPED----FEQDGEEAALAPGA 1179 Query: 353 P---------------DRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYG 397 P + A P+ L PP ++ E PG + Sbjct: 1180 PAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAML- 1238 Query: 398 LEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGAL-LGAPPPLVPA--PRPSSPPRGP 453 L P P PP P AP + PP L L PPL P PRP SPP P Sbjct: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEP 1297 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/128 (28%), Positives = 42/128 (32%), Gaps = 13/128 (10%) Query: 332 PQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAP--PRLARPPRFYEAGEELTGPGA 389 P L P P P L P+P C P P PR + P G + P Sbjct: 1444 PAVLRAQARAPTPLPPLLPAPLASCP----PPMKRKPGRPRRSPPSMLSLDGPLVRPPAG 1499 Query: 390 VAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSP 449 A R L P P P P P T L + + PPPL P P P P Sbjct: 1500 AALGRELLLLPGQPQ-----TPVFPSTHDPRTVTLDFRN--AGIPAPPPPLPPQPPPPPP 1552 Query: 450 PRGPGPAR 457 P P + Sbjct: 1553 PPPVEPTK 1560 >gi|239757043 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 996 Score = 55.1 bits (131), Expect = 1e-07 Identities = 54/173 (31%), Positives = 66/173 (38%), Gaps = 24/173 (13%) Query: 308 KEEAAAAAAAAAAAAAAAAAAATGPQGLHLLF-----ERPRPPPFLGPSPPDRCAGFLEP 362 K+E A AAA A A A A A GL LF + PPF PP G P Sbjct: 423 KKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVP 482 Query: 363 TWLAAPPRLAR---------PPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAP-- 411 T+L PP+ P +A +L PG A + P P P Sbjct: 483 TYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGS 542 Query: 412 -PPPPAAAPGTPHLLSKTPPG-----ALLGAPPPL--VPAPRPSSPPRGPGPA 456 PPPPA G+ L ++PPG G+ PP V A + G GPA Sbjct: 543 GPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/83 (39%), Positives = 38/83 (45%), Gaps = 10/83 (12%) Query: 313 AAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLA 372 ++ AAA AAAAA A G G HLL P PPP P P AG AP Sbjct: 257 SSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPP--PPPPLAELAG--------APHAHH 306 Query: 373 RPPRFYEAGEELTGPGAVAAARL 395 + PRF + + L VAAA L Sbjct: 307 KRPRFDDDDDSLQEAAVVAAASL 329 Score = 30.0 bits (66), Expect = 4.6 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 397 GLEPA-HPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGP 455 G PA HPL + A AA G LL LLGAPPP P P P + G Sbjct: 248 GAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPH----LLGAPPPPPPPPPPLAELAGAPH 303 Query: 456 ARADR 460 A R Sbjct: 304 AHHKR 308 Score = 29.6 bits (65), Expect = 6.0 Identities = 17/50 (34%), Positives = 19/50 (38%), Gaps = 6/50 (12%) Query: 380 AGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTP 429 A + G G + L G P P PPPP A G PH K P Sbjct: 266 AAAAVAGGGGLLGPHLLGAPPPPP------PPPPPLAELAGAPHAHHKRP 309 >gi|239751555 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 55.1 bits (131), Expect = 1e-07 Identities = 54/173 (31%), Positives = 66/173 (38%), Gaps = 24/173 (13%) Query: 308 KEEAAAAAAAAAAAAAAAAAAATGPQGLHLLF-----ERPRPPPFLGPSPPDRCAGFLEP 362 K+E A AAA A A A A A GL LF + PPF PP G P Sbjct: 423 KKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVP 482 Query: 363 TWLAAPPRLAR---------PPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAP-- 411 T+L PP+ P +A +L PG A + P P P Sbjct: 483 TYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGS 542 Query: 412 -PPPPAAAPGTPHLLSKTPPG-----ALLGAPPPL--VPAPRPSSPPRGPGPA 456 PPPPA G+ L ++PPG G+ PP V A + G GPA Sbjct: 543 GPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/83 (39%), Positives = 38/83 (45%), Gaps = 10/83 (12%) Query: 313 AAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLA 372 ++ AAA AAAAA A G G HLL P PPP P P AG AP Sbjct: 257 SSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPP--PPPPLAELAG--------APHAHH 306 Query: 373 RPPRFYEAGEELTGPGAVAAARL 395 + PRF + + L VAAA L Sbjct: 307 KRPRFDDDDDSLQEAAVVAAASL 329 Score = 30.0 bits (66), Expect = 4.6 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 397 GLEPA-HPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGP 455 G PA HPL + A AA G LL LLGAPPP P P P + G Sbjct: 248 GAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPH----LLGAPPPPPPPPPPLAELAGAPH 303 Query: 456 ARADR 460 A R Sbjct: 304 AHHKR 308 Score = 29.6 bits (65), Expect = 6.0 Identities = 17/50 (34%), Positives = 19/50 (38%), Gaps = 6/50 (12%) Query: 380 AGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTP 429 A + G G + L G P P PPPP A G PH K P Sbjct: 266 AAAAVAGGGGLLGPHLLGAPPPPP------PPPPPLAELAGAPHAHHKRP 309 >gi|239746067 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 55.1 bits (131), Expect = 1e-07 Identities = 54/173 (31%), Positives = 66/173 (38%), Gaps = 24/173 (13%) Query: 308 KEEAAAAAAAAAAAAAAAAAAATGPQGLHLLF-----ERPRPPPFLGPSPPDRCAGFLEP 362 K+E A AAA A A A A A GL LF + PPF PP G P Sbjct: 423 KKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVP 482 Query: 363 TWLAAPPRLAR---------PPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAP-- 411 T+L PP+ P +A +L PG A + P P P Sbjct: 483 TYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGS 542 Query: 412 -PPPPAAAPGTPHLLSKTPPG-----ALLGAPPPL--VPAPRPSSPPRGPGPA 456 PPPPA G+ L ++PPG G+ PP V A + G GPA Sbjct: 543 GPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/83 (39%), Positives = 38/83 (45%), Gaps = 10/83 (12%) Query: 313 AAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLA 372 ++ AAA AAAAA A G G HLL P PPP P P AG AP Sbjct: 257 SSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPP--PPPPLAELAG--------APHAHH 306 Query: 373 RPPRFYEAGEELTGPGAVAAARL 395 + PRF + + L VAAA L Sbjct: 307 KRPRFDDDDDSLQEAAVVAAASL 329 Score = 30.0 bits (66), Expect = 4.6 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 397 GLEPA-HPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGP 455 G PA HPL + A AA G LL LLGAPPP P P P + G Sbjct: 248 GAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPH----LLGAPPPPPPPPPPLAELAGAPH 303 Query: 456 ARADR 460 A R Sbjct: 304 AHHKR 308 Score = 29.6 bits (65), Expect = 6.0 Identities = 17/50 (34%), Positives = 19/50 (38%), Gaps = 6/50 (12%) Query: 380 AGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTP 429 A + G G + L G P P PPPP A G PH K P Sbjct: 266 AAAAVAGGGGLLGPHLLGAPPPPP------PPPPPLAELAGAPHAHHKRP 309 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 54.7 bits (130), Expect = 2e-07 Identities = 105/375 (28%), Positives = 127/375 (33%), Gaps = 61/375 (16%) Query: 106 GDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFL 165 GD + DLL P P A P Q++S P G + P TA P P L Sbjct: 126 GDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP------PGGSPLPSPPSTAPP---PPPL 176 Query: 166 SPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPP-AFASPPDPW 224 P P L ALS L SP+ + F P APP AF +PP P Sbjct: 177 LLEPPPPPSMAPPPPPVLEALSPP--HTLSSPSIPTPPDFI----PPAPPLAFLAPPPP- 229 Query: 225 GRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKD-----RDLPFSRPQLR 279 P+ PA P + T G+ P +TK + D R +R Sbjct: 230 ------PVPAPA-PPAPASPHTVGTRLFPP-----GGVTKWKSDVALNGRQAEATRASPP 277 Query: 280 VSPATPKARAGEEGPR-----------PTKESVRVKEERKEEAAAAAAAAAAAAAAAAAA 328 SPA PK A P P VR +EA A A A + Sbjct: 278 RSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337 Query: 329 ATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPG 388 P H+ RP + +P C G L+ T A PRL + +A E P Sbjct: 338 LPLPPSFHI---RPASQVYPDRAPEPDCPGELKAT-APASPRLGQSQS--QADERAGTPP 391 Query: 389 AVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAP----PPLVPAP 444 PA PL APP PPAA P + PP P P L P P Sbjct: 392 PAPPLP----PPAPPL--PPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445 Query: 445 RPSSPPRGPGPARAD 459 P SP A D Sbjct: 446 NPPSPENTASSAPVD 460 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 380 AGEELTGPGAVAAA--RLYG-LEPAHPLLYSR--LAPPPPPAAAPGTPHLLSKTPPGALL 434 A +E+TG ++ RLY + P Y + L PPPPP APG P +S+ P G+ L Sbjct: 104 ADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPL 163 Query: 435 GAPPPLVPAPRP--SSPPRGPGPA 456 +PP P P P PP P A Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMA 187 Score = 35.0 bits (79), Expect = 0.14 Identities = 98/402 (24%), Positives = 122/402 (30%), Gaps = 96/402 (23%) Query: 118 LPCLPGPYGALPPGQEL---SHPASLFTATGAVHAAANPFTAAPGAHGPFLS------PS 168 +P P A+PP L + P + + A + P T GP ++ P+ Sbjct: 641 IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700 Query: 169 THID--------PFGRPTSFASLAALSNGAFGGLGSPT---------FNSGAVFAQKESP 211 T P G+P AS + G GSP+ S A F K SP Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760 Query: 212 GAP--PAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDR 269 G P P H+S L+ V P AR + PVE +EP Sbjct: 761 GGGEVPCLYKP-----HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP--------- 806 Query: 270 DLPFSRPQLRVSPATPKARAGEEGPRPTKESVR------VKEERKEEAAAAAAAAAAAAA 323 P L PA P A A +PT E +R V E A AA A Sbjct: 807 ------PGL---PAKPPASA-----QPTDELLRHPVTGEVVERGSPMALLLAARQRAQKG 852 Query: 324 AAAAAATGPQGL----------------HLLFERPRPPPFLGPSPPDRCAGFLEPTWLAA 367 + AA G L + + P F + A P Sbjct: 853 RSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEI 912 Query: 368 P----PRLARPPRFYEAGE-------ELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPA 416 P PRL R E E P A L HPL S +PP P Sbjct: 913 PNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSN 972 Query: 417 AAPGTPHLLS---KTPPGALLGAPPPLVPA----PRPSSPPR 451 + PP P P PA R SSPPR Sbjct: 973 KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014 Score = 33.1 bits (74), Expect = 0.54 Identities = 108/494 (21%), Positives = 151/494 (30%), Gaps = 98/494 (19%) Query: 17 PYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHF 76 P+T P++P P +PPA L P +P P P+ GT+ Sbjct: 200 PHTLSSPSIPTPPDFIPPAPPLAFLA------PPPPPVPAPAPPAPASPHTVGTR----- 248 Query: 77 RPPLRKPG---KW---CAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPP 130 L PG KW A++ R A + + + L P P+ P Sbjct: 249 ---LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEP-----KGSALGPNPEPHLTFPR 300 Query: 131 GQELSHPASLFTATGAVHAAANPFTAAPGAHGPF-----LSPSTHIDPFGR--------P 177 ++ P + T++ V A GA L PS HI P + P Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360 Query: 178 TSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAW 237 L A + SP A + + PPA PP PL PA Sbjct: 361 DCPGELKATAPA------SPRLGQSQSQADERAGTPPPAPPLPPPA------PPLPPPAP 408 Query: 238 VRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKAR-AGEEGPRP 296 PP A P + K TK K S P L+ P P P Sbjct: 409 PLPPAAPPLPCAQK---AAHPPAGFTKTPKS-----SSPALKPKPNPPSPENTASSAPVD 460 Query: 297 TKESVRVKEERKEEAAAAAAAAAA--------AAAAAAAAATGPQGLHLLFERPR---PP 345 ++ ++++ R E AA + A + G +G L + P Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520 Query: 346 PFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFY---------------EAGEELTGPGAV 390 P P++ G T A P L P Y E L+ Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580 Query: 391 AAARLYGLEPAHPLLYS-----------RLAPPPPPAAAPGTPHLLSKTP--PGALLGAP 437 A G P P L +L+ P P + LL T P A+LG Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640 Query: 438 PPLVPAPRPSSPPR 451 P P P+ PP+ Sbjct: 641 IPPKATPEPAIPPK 654 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 54.7 bits (130), Expect = 2e-07 Identities = 105/375 (28%), Positives = 127/375 (33%), Gaps = 61/375 (16%) Query: 106 GDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFL 165 GD + DLL P P A P Q++S P G + P TA P P L Sbjct: 126 GDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP------PGGSPLPSPPSTAPP---PPPL 176 Query: 166 SPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPP-AFASPPDPW 224 P P L ALS L SP+ + F P APP AF +PP P Sbjct: 177 LLEPPPPPSMAPPPPPVLEALSPP--HTLSSPSIPTPPDFI----PPAPPLAFLAPPPP- 229 Query: 225 GRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKD-----RDLPFSRPQLR 279 P+ PA P + T G+ P +TK + D R +R Sbjct: 230 ------PVPAPA-PPAPASPHTVGTRLFPP-----GGVTKWKSDVALNGRQAEATRASPP 277 Query: 280 VSPATPKARAGEEGPR-----------PTKESVRVKEERKEEAAAAAAAAAAAAAAAAAA 328 SPA PK A P P VR +EA A A A + Sbjct: 278 RSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337 Query: 329 ATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPG 388 P H+ RP + +P C G L+ T A PRL + +A E P Sbjct: 338 LPLPPSFHI---RPASQVYPDRAPEPDCPGELKAT-APASPRLGQSQS--QADERAGTPP 391 Query: 389 AVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAP----PPLVPAP 444 PA PL APP PPAA P + PP P P L P P Sbjct: 392 PAPPLP----PPAPPL--PPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445 Query: 445 RPSSPPRGPGPARAD 459 P SP A D Sbjct: 446 NPPSPENTASSAPVD 460 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 380 AGEELTGPGAVAAA--RLYG-LEPAHPLLYSR--LAPPPPPAAAPGTPHLLSKTPPGALL 434 A +E+TG ++ RLY + P Y + L PPPPP APG P +S+ P G+ L Sbjct: 104 ADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPL 163 Query: 435 GAPPPLVPAPRP--SSPPRGPGPA 456 +PP P P P PP P A Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMA 187 Score = 35.0 bits (79), Expect = 0.14 Identities = 98/402 (24%), Positives = 122/402 (30%), Gaps = 96/402 (23%) Query: 118 LPCLPGPYGALPPGQEL---SHPASLFTATGAVHAAANPFTAAPGAHGPFLS------PS 168 +P P A+PP L + P + + A + P T GP ++ P+ Sbjct: 641 IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700 Query: 169 THID--------PFGRPTSFASLAALSNGAFGGLGSPT---------FNSGAVFAQKESP 211 T P G+P AS + G GSP+ S A F K SP Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760 Query: 212 GAP--PAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDR 269 G P P H+S L+ V P AR + PVE +EP Sbjct: 761 GGGEVPCLYKP-----HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP--------- 806 Query: 270 DLPFSRPQLRVSPATPKARAGEEGPRPTKESVR------VKEERKEEAAAAAAAAAAAAA 323 P L PA P A A +PT E +R V E A AA A Sbjct: 807 ------PGL---PAKPPASA-----QPTDELLRHPVTGEVVERGSPMALLLAARQRAQKG 852 Query: 324 AAAAAATGPQGL----------------HLLFERPRPPPFLGPSPPDRCAGFLEPTWLAA 367 + AA G L + + P F + A P Sbjct: 853 RSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEI 912 Query: 368 P----PRLARPPRFYEAGE-------ELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPA 416 P PRL R E E P A L HPL S +PP P Sbjct: 913 PNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSN 972 Query: 417 AAPGTPHLLS---KTPPGALLGAPPPLVPA----PRPSSPPR 451 + PP P P PA R SSPPR Sbjct: 973 KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014 Score = 33.1 bits (74), Expect = 0.54 Identities = 108/494 (21%), Positives = 151/494 (30%), Gaps = 98/494 (19%) Query: 17 PYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHF 76 P+T P++P P +PPA L P +P P P+ GT+ Sbjct: 200 PHTLSSPSIPTPPDFIPPAPPLAFLA------PPPPPVPAPAPPAPASPHTVGTR----- 248 Query: 77 RPPLRKPG---KW---CAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPP 130 L PG KW A++ R A + + + L P P+ P Sbjct: 249 ---LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEP-----KGSALGPNPEPHLTFPR 300 Query: 131 GQELSHPASLFTATGAVHAAANPFTAAPGAHGPF-----LSPSTHIDPFGR--------P 177 ++ P + T++ V A GA L PS HI P + P Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360 Query: 178 TSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAW 237 L A + SP A + + PPA PP PL PA Sbjct: 361 DCPGELKATAPA------SPRLGQSQSQADERAGTPPPAPPLPPPA------PPLPPPAP 408 Query: 238 VRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKAR-AGEEGPRP 296 PP A P + K TK K S P L+ P P P Sbjct: 409 PLPPAAPPLPCAQK---AAHPPAGFTKTPKS-----SSPALKPKPNPPSPENTASSAPVD 460 Query: 297 TKESVRVKEERKEEAAAAAAAAAA--------AAAAAAAAATGPQGLHLLFERPR---PP 345 ++ ++++ R E AA + A + G +G L + P Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520 Query: 346 PFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFY---------------EAGEELTGPGAV 390 P P++ G T A P L P Y E L+ Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580 Query: 391 AAARLYGLEPAHPLLYS-----------RLAPPPPPAAAPGTPHLLSKTP--PGALLGAP 437 A G P P L +L+ P P + LL T P A+LG Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640 Query: 438 PPLVPAPRPSSPPR 451 P P P+ PP+ Sbjct: 641 IPPKATPEPAIPPK 654 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 54.7 bits (130), Expect = 2e-07 Identities = 105/375 (28%), Positives = 127/375 (33%), Gaps = 61/375 (16%) Query: 106 GDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFL 165 GD + DLL P P A P Q++S P G + P TA P P L Sbjct: 126 GDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP------PGGSPLPSPPSTAPP---PPPL 176 Query: 166 SPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPP-AFASPPDPW 224 P P L ALS L SP+ + F P APP AF +PP P Sbjct: 177 LLEPPPPPSMAPPPPPVLEALSPP--HTLSSPSIPTPPDFI----PPAPPLAFLAPPPP- 229 Query: 225 GRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKD-----RDLPFSRPQLR 279 P+ PA P + T G+ P +TK + D R +R Sbjct: 230 ------PVPAPA-PPAPASPHTVGTRLFPP-----GGVTKWKSDVALNGRQAEATRASPP 277 Query: 280 VSPATPKARAGEEGPR-----------PTKESVRVKEERKEEAAAAAAAAAAAAAAAAAA 328 SPA PK A P P VR +EA A A A + Sbjct: 278 RSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337 Query: 329 ATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPG 388 P H+ RP + +P C G L+ T A PRL + +A E P Sbjct: 338 LPLPPSFHI---RPASQVYPDRAPEPDCPGELKAT-APASPRLGQSQS--QADERAGTPP 391 Query: 389 AVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAP----PPLVPAP 444 PA PL APP PPAA P + PP P P L P P Sbjct: 392 PAPPLP----PPAPPL--PPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445 Query: 445 RPSSPPRGPGPARAD 459 P SP A D Sbjct: 446 NPPSPENTASSAPVD 460 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 380 AGEELTGPGAVAAA--RLYG-LEPAHPLLYSR--LAPPPPPAAAPGTPHLLSKTPPGALL 434 A +E+TG ++ RLY + P Y + L PPPPP APG P +S+ P G+ L Sbjct: 104 ADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPL 163 Query: 435 GAPPPLVPAPRP--SSPPRGPGPA 456 +PP P P P PP P A Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMA 187 Score = 35.0 bits (79), Expect = 0.14 Identities = 98/402 (24%), Positives = 122/402 (30%), Gaps = 96/402 (23%) Query: 118 LPCLPGPYGALPPGQEL---SHPASLFTATGAVHAAANPFTAAPGAHGPFLS------PS 168 +P P A+PP L + P + + A + P T GP ++ P+ Sbjct: 641 IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700 Query: 169 THID--------PFGRPTSFASLAALSNGAFGGLGSPT---------FNSGAVFAQKESP 211 T P G+P AS + G GSP+ S A F K SP Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760 Query: 212 GAP--PAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDR 269 G P P H+S L+ V P AR + PVE +EP Sbjct: 761 GGGEVPCLYKP-----HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP--------- 806 Query: 270 DLPFSRPQLRVSPATPKARAGEEGPRPTKESVR------VKEERKEEAAAAAAAAAAAAA 323 P L PA P A A +PT E +R V E A AA A Sbjct: 807 ------PGL---PAKPPASA-----QPTDELLRHPVTGEVVERGSPMALLLAARQRAQKG 852 Query: 324 AAAAAATGPQGL----------------HLLFERPRPPPFLGPSPPDRCAGFLEPTWLAA 367 + AA G L + + P F + A P Sbjct: 853 RSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEI 912 Query: 368 P----PRLARPPRFYEAGE-------ELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPA 416 P PRL R E E P A L HPL S +PP P Sbjct: 913 PNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSN 972 Query: 417 AAPGTPHLLS---KTPPGALLGAPPPLVPA----PRPSSPPR 451 + PP P P PA R SSPPR Sbjct: 973 KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014 Score = 33.1 bits (74), Expect = 0.54 Identities = 108/494 (21%), Positives = 151/494 (30%), Gaps = 98/494 (19%) Query: 17 PYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHF 76 P+T P++P P +PPA L P +P P P+ GT+ Sbjct: 200 PHTLSSPSIPTPPDFIPPAPPLAFLA------PPPPPVPAPAPPAPASPHTVGTR----- 248 Query: 77 RPPLRKPG---KW---CAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPP 130 L PG KW A++ R A + + + L P P+ P Sbjct: 249 ---LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEP-----KGSALGPNPEPHLTFPR 300 Query: 131 GQELSHPASLFTATGAVHAAANPFTAAPGAHGPF-----LSPSTHIDPFGR--------P 177 ++ P + T++ V A GA L PS HI P + P Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360 Query: 178 TSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAW 237 L A + SP A + + PPA PP PL PA Sbjct: 361 DCPGELKATAPA------SPRLGQSQSQADERAGTPPPAPPLPPPA------PPLPPPAP 408 Query: 238 VRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKAR-AGEEGPRP 296 PP A P + K TK K S P L+ P P P Sbjct: 409 PLPPAAPPLPCAQK---AAHPPAGFTKTPKS-----SSPALKPKPNPPSPENTASSAPVD 460 Query: 297 TKESVRVKEERKEEAAAAAAAAAA--------AAAAAAAAATGPQGLHLLFERPR---PP 345 ++ ++++ R E AA + A + G +G L + P Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520 Query: 346 PFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFY---------------EAGEELTGPGAV 390 P P++ G T A P L P Y E L+ Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580 Query: 391 AAARLYGLEPAHPLLYS-----------RLAPPPPPAAAPGTPHLLSKTP--PGALLGAP 437 A G P P L +L+ P P + LL T P A+LG Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640 Query: 438 PPLVPAPRPSSPPR 451 P P P+ PP+ Sbjct: 641 IPPKATPEPAIPPK 654 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 54.7 bits (130), Expect = 2e-07 Identities = 48/139 (34%), Positives = 58/139 (41%), Gaps = 25/139 (17%) Query: 342 PRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPA 401 P P P P+P A E T PPR A P + + E P A R PA Sbjct: 513 PAPAPAPAPAPALASAATKERTESEVPPRPASP-KVTRSPPETAAPVEDMARRTKRPAPA 571 Query: 402 HPLLY------SRLAPPPPP----AAAPGTPHLLSKTPPGALLGA---PPPLVPAP---- 444 P + SR +PP PP + +PGTP L + G+ L A PPPL P P Sbjct: 572 RPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPA 631 Query: 445 ------RPSSP-PRGPGPA 456 P+SP P PGPA Sbjct: 632 RRQSRRSPASPSPASPGPA 650 >gi|26190608 synaptojanin 2 [Homo sapiens] Length = 1496 Score = 52.8 bits (125), Expect = 7e-07 Identities = 64/254 (25%), Positives = 86/254 (33%), Gaps = 37/254 (14%) Query: 228 HRSP---LTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPAT 284 HRSP L+ P RPP+ + P V++ + R+ P Sbjct: 1089 HRSPSRSLSVPNRPRPPQPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTARLLPGA 1148 Query: 285 P----KARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLF- 339 P KAR G P K+ + E A A A+ A +A P+ L Sbjct: 1149 PQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEARGGASEEALSAVAPRDLEASSE 1208 Query: 340 ----------ERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELT-GPG 388 E P+ PP L PP R +PT L+ +F + T GP Sbjct: 1209 PEPTPGAAKPETPQAPPLLPRRPPPRVPAIKKPTLRRTGKPLSPEEQFEQQTVHFTIGPP 1268 Query: 389 AVAAARLYGLEPAHPLLYSRLAPPPP------PAAAPGTPH----LLSKTPPGALLGAPP 438 + A P++ + PP P P A P + PPGA PP Sbjct: 1269 ETSV-------EAPPVVTAPRVPPVPKPRTFQPGKAAERPSHRKPASDEAPPGAGASVPP 1321 Query: 439 PLVPAPR-PSSPPR 451 PL P P PPR Sbjct: 1322 PLEAPPLVPKVPPR 1335 >gi|102469037 jun D proto-oncogene [Homo sapiens] Length = 347 Score = 52.0 bits (123), Expect = 1e-06 Identities = 78/284 (27%), Positives = 99/284 (34%), Gaps = 64/284 (22%) Query: 190 AFGGLGSPTFNSGAVFAQ--KESPGAPPAFASPPDPWGRLHRSPLTF-----------PA 236 A GLG SG FA + PGAPP A+ + + LT PA Sbjct: 10 ALSGLGGGASGSGGSFASPGRLFPGAPPTAAAG----SMMKKDALTLSLSEQVAAALKPA 65 Query: 237 WVRPPEAARTPGSDKERPVERREPS-------ITKEEKDRDLPFSRPQLRVSPAT----- 284 PP R G+ P + S + E +R + S + +P + Sbjct: 66 AAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSSQFLY 125 Query: 285 PKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRP 344 PK A EE +++ K+ A AAAAAAAAAA GP G Sbjct: 126 PKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAG----GPSGTAT------- 174 Query: 345 PPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPL 404 G +PP G L P AA P P + G G A A P+ Sbjct: 175 ----GSAPP----GELAPA--AAAPEA---PVYANLSSYAGGAGGAGGAATVAFA-AEPV 220 Query: 405 LYSRLAPPPPPAAAPGTPHLLS------KTPPGALLGAPPPLVP 442 + PPPPP A G P L + P G PPL P Sbjct: 221 PF----PPPPPPGALGPPRLAALKDEPQTVPDVPSFGESPPLSP 260 >gi|40353727 synaptopodin isoform A [Homo sapiens] Length = 903 Score = 52.0 bits (123), Expect = 1e-06 Identities = 72/280 (25%), Positives = 103/280 (36%), Gaps = 30/280 (10%) Query: 196 SPTFNSGAVFAQKESPGAPPAFASPPD-PWGRLHRSPLTFPAWVRPPEAARTPGSDKERP 254 SP V + SP P + P+ P G L SP P +PG D +P Sbjct: 575 SPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 Query: 255 VERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRP---TKESVRVKEERKEEA 311 P + VSP+ + ++ PRP T+ + ++R+E Sbjct: 635 TAVSPP------------YGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESL 682 Query: 312 AAAAAAAAAAAAAAAA----AATGP----QGLHLLFERPRPPPF-LGPSPPDRCAGFLEP 362 + A+ ++ + GP +G + P PPP + PS +R L P Sbjct: 683 PTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRP 742 Query: 363 TWLAAPPRLARPPRFYEAGEELTGPGAVAAA-RLYGLEPAHPLLYSRLAPPPPPAAAPGT 421 A PP +R + A + +A+ R G E P R APPPPP P Sbjct: 743 ETEARPP--SRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR-APPPPPPPPPPP 799 Query: 422 PHLLSKTPPGALLGAPPPLVPAPRPSSP-PRGPGPARADR 460 P + S P A P AP P SP P GP + R Sbjct: 800 PRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPR 839 Score = 45.8 bits (107), Expect = 8e-05 Identities = 85/320 (26%), Positives = 109/320 (34%), Gaps = 67/320 (20%) Query: 116 DLLPCLPGPYGALPPGQELSHPA----SLFTATGAVHAAANPFTAAPGAHGPF--LSPST 169 DL+P LP GALPP L P+ L+T+ G + P +P G +SPS Sbjct: 597 DLVPNLPK--GALPPSPALPRPSRSSPGLYTSPG--QDSLQPTAVSPPYGGDISPVSPSR 652 Query: 170 HIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHR 229 P + S + T N+G + AQ P SPP G R Sbjct: 653 AWSPRAKQAPRPSFS-------------TRNAG-IEAQDRRESLP---TSPPWTPG-ASR 694 Query: 230 SPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARA 289 P + WV P GS P P + S + VSP P+ A Sbjct: 695 PPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPP--------PMSPSWSERSVSPLRPETEA 746 Query: 290 GEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLG 349 RP ++ R AA +A+ +A A P+ F PR PP Sbjct: 747 -----RPPSRQLQALLARN----IINAARRKSASPRSAGAENPRP----FSPPRAPPPPP 793 Query: 350 PSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRL 409 P PP PP R P+ G PGA A PA P S Sbjct: 794 PPPP--------------PPPRMRSPQPARPGSAAV-PGAAFAPIPRSPLPAGP---SSC 835 Query: 410 APPPPPAAAPGTPHLLSKTP 429 P P AP P L ++P Sbjct: 836 TSPRSPLPAPPRPFLYRRSP 855 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 52.0 bits (123), Expect = 1e-06 Identities = 86/339 (25%), Positives = 110/339 (32%), Gaps = 59/339 (17%) Query: 122 PGPY---GALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPT 178 PGP+ G LPPG S P L APG H ++P + P T Sbjct: 782 PGPHYLSGPLPPGT-YSGPTQLIQPR------------APGPHAMPVAPGPALYPAPAYT 828 Query: 179 SFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWV 238 L S+ G + SP G P APP S P+ V Sbjct: 829 PELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPE-----------LAMAV 877 Query: 239 RPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTK 298 RP A T + P+ PS T P+ +PA P P+P Sbjct: 878 RP---ATTTVDSIQAPI----PSHTA-----------PRPNPTPAPPPPCFPVPPPQPLP 919 Query: 299 ESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAG 358 K+ A ++ A A GPQ +P P GP PP + Sbjct: 920 TPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQP--HPQPHPSQAFGPQPPQQPLP 977 Query: 359 FLEP-TWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAA 417 P + P L P Y + PG + G P P L+++L P P Sbjct: 978 LQHPHLFPPQAPGLLPPQSPYPYAPQ---PGVL------GQPP--PPLHTQLYPGPAQDP 1026 Query: 418 APGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPA 456 P L PG PPL P PS+ P GP A Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAA 1065 Score = 35.0 bits (79), Expect = 0.14 Identities = 33/86 (38%), Positives = 38/86 (44%), Gaps = 10/86 (11%) Query: 379 EAG---EELTG--PGAVAAARLYG--LEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPG 431 EAG EEL P VA RL L A PL + P P + PG +L PPG Sbjct: 737 EAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFP--PSPFPSSTGPGPHYLSGPLPPG 794 Query: 432 ALLGAPPPLVP-APRPSSPPRGPGPA 456 G + P AP P + P PGPA Sbjct: 795 TYSGPTQLIQPRAPGPHAMPVAPGPA 820 Score = 30.8 bits (68), Expect = 2.7 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 410 APPP--PPAAAPGTPHLLSKTPP---GALLGAPPPLVPAPRPSSPPRGP 453 A PP PPA+ P + + S +PP L AP P P P +P GP Sbjct: 1524 AEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGP 1572 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 51.6 bits (122), Expect = 1e-06 Identities = 127/501 (25%), Positives = 163/501 (32%), Gaps = 136/501 (27%) Query: 19 TAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHFRP 78 T PP +P PP LPP P P PP P+P GL+ P Sbjct: 238 TGLPPGLPLPPPPLPP------------PPPPPPPPPP---PLP-GLATS---------P 272 Query: 79 P--LRKPGKWCAMH------VRVAYMILRHQEKMKGDSHKLDF----------RNDLLPC 120 P L KPG W +H R QE+ H + + L+P Sbjct: 273 PFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPA 332 Query: 121 LPGPYGALPPGQELSH---PASL-----------------FTATGAVHAAANPFTAA--P 158 P G PPG E SH PA+ + + A A P+ + P Sbjct: 333 APPGPGPRPPGAE-SHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPP 391 Query: 159 GAHGPFLSPSTH---------IDPF-GRP-TSFASLAALSNGAFGGLGSPTFNS-----G 202 G G S S+ ++P G P AL G LG +S G Sbjct: 392 GLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLG 451 Query: 203 AVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPP--EAARTPGS-------DKER 253 A A P + PP P RL R P PAW++ P AAR G E Sbjct: 452 APAATPHLSLPPGPSSPPPPPCPRLLRPPPP-PAWLKGPACRAAREDGEILEELFFGTEG 510 Query: 254 PVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAA 313 P P + E P S R S T + P PT S + + Sbjct: 511 PPRPAPPPLPHREGFLGPPAS----RFSVGTQDSHTPPTPPTPTTSS----------SNS 556 Query: 314 AAAAAAAAAAAAAAAATGPQGLHLLFERPRPP-PFLGPSPPDRCAGFLEPTWLAAPPRLA 372 + + +++ A + P + PRPP P P P L P LA PP Sbjct: 557 NSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPP-----LVPLTLALPP--- 608 Query: 373 RPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGA 432 PP + +G + R P P + P TP + PPG Sbjct: 609 APPS--SCHQNTSGS------------------FRRPESPRPRVSFPKTPEVGPGPPPGP 648 Query: 433 LLGAPPPLVPAPRPSSPPRGP 453 L AP P VP P RGP Sbjct: 649 LSKAPQP-VPPGVGELPARGP 668 Score = 51.6 bits (122), Expect = 1e-06 Identities = 127/498 (25%), Positives = 162/498 (32%), Gaps = 131/498 (26%) Query: 27 GLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQKGTQIPDHFRPPLRKPGKW 86 GLPPGLP P P PP P P L T P L KPG W Sbjct: 239 GLPPGLP------------LPPPPLPPPPPPPPPPPPPLPGLATSPPFQ----LTKPGLW 282 Query: 87 CAMH------VRVAYMILRHQEKMKGDSHKLDFR----------NDLLPCLPGPYGALPP 130 +H R QE+ H + + L+P P G PP Sbjct: 283 STLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPP 342 Query: 131 GQELSH---PASL-----------------FTATGAVHAAANPFTAA--PGAHGPFLSPS 168 G E SH PA+ + + A A P+ + PG G S S Sbjct: 343 GAE-SHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSS 401 Query: 169 TH---------IDPF-GRP-TSFASLAALSNGAFGGLGSPTFNSGAVF--AQKESP--GA 213 + ++P G P AL G LG +S F A +P Sbjct: 402 SSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSL 461 Query: 214 PPAFASPPDP-WGRLHRSPLTFPAWVRPP--EAARTPGS-------DKERPVERREPSIT 263 PP +SPP P RL R P PAW++ P AAR G E P P + Sbjct: 462 PPGPSSPPPPPCPRLLRPPPP-PAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP 520 Query: 264 KEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAA 323 E P SR S T + P PT S + + + + +++ A Sbjct: 521 HREGFLGPPASR----FSVGTQDSHTPPTPPTPTTSS----------SNSNSGSHSSSPA 566 Query: 324 AAAAAATGPQGLHLLFERPRPP-PFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGE 382 + P + PRPP P P P L P LA PP PP + Sbjct: 567 GPVSFPPPPYLARSIDPLPRPPSPAQNPQDPP-----LVPLTLALPPA---PPS--SCHQ 616 Query: 383 ELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVP 442 +G + R P P + P TP + PPG PL Sbjct: 617 NTSGS------------------FRRPESPRPRVSFPKTPEVGPGPPPG-------PLSK 651 Query: 443 APRPSSPPRGPGPARADR 460 AP+P P G PAR R Sbjct: 652 APQPVPPGVGELPARGPR 669 Score = 42.7 bits (99), Expect = 7e-04 Identities = 93/378 (24%), Positives = 130/378 (34%), Gaps = 77/378 (20%) Query: 119 PCLPGPYGALPP-------GQELSH--PASLFTATGAVHAAANPFTAAPGAHGPFLSP-- 167 P LP G L P G + SH P T + ++ + +++P F P Sbjct: 517 PPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPY 576 Query: 168 -STHIDPFGRPTSFAS------LAALSNGAFGGLGSPTF-NSGAVFAQKESPGAPPAFAS 219 + IDP RP S A L L+ S N+ F + ESP +F Sbjct: 577 LARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPK 636 Query: 220 PPD-----PWGRLHRSPLTFPAWVR--PPEAAR------TPGSDK-ERPVERR------- 258 P+ P G L ++P P V P R TP D+ E P E + Sbjct: 637 TPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLA 696 Query: 259 ------EPSITKEEKDRDLPFSRPQLRVSPATPKAR--AGEEGPRPTKESVRVKEERKEE 310 + SI KEE+ + + + V+P P A + P PT + Sbjct: 697 NIMKMLDESIRKEEEQQ-----QHEAGVAPQPPLKEPFASLQSPFPTDTA---------P 742 Query: 311 AAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPR 370 A A A T Q E +PPP L P PP A F P+ PP Sbjct: 743 TTTAPAVAVTTTTTTTTTTTATQE-----EEKKPPPALPPPPP--LAKFPPPSQPQPPP- 794 Query: 371 LARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPP 430 PP L +V + Y + +R P P +PG P + PP Sbjct: 795 -PPPP---SPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPP 850 Query: 431 GALLGAPPPLVPAPRPSS 448 A P +P+PS+ Sbjct: 851 ---TSAAPSAQGSPQPSA 865 Score = 31.2 bits (69), Expect = 2.1 Identities = 27/84 (32%), Positives = 32/84 (38%), Gaps = 9/84 (10%) Query: 381 GEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLL------SKTPPGALL 434 G + GP AA ++P P S P +PG + PPG L Sbjct: 189 GAKRGGPPVKRAAEPPVVQPVPPAALS--GPSGEEGLSPGGKRRRGCNSEQTGLPPGLPL 246 Query: 435 GAPPPLVPAPRPSSPPRGPGPARA 458 PPPL P P P PP P P A Sbjct: 247 -PPPPLPPPPPPPPPPPPPLPGLA 269 Score = 30.0 bits (66), Expect = 4.6 Identities = 39/142 (27%), Positives = 46/142 (32%), Gaps = 43/142 (30%) Query: 340 ERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAA----ARL 395 +R PP + P PP +G +GEE PG + Sbjct: 198 KRAAEPPVVQPVPPAALSG--------------------PSGEEGLSPGGKRRRGCNSEQ 237 Query: 396 YGLEPAHPLLYSRLAPPPPPA--AAPGTPHLLSKTP-----PG------------ALLGA 436 GL P PL L PPPPP P P L + P PG G+ Sbjct: 238 TGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGS 297 Query: 437 PPPLVPAPRPSSPPRGPGPARA 458 PP R S P P PA A Sbjct: 298 APPERQEQRHSLPHPYPYPAPA 319 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 51.2 bits (121), Expect = 2e-06 Identities = 77/318 (24%), Positives = 111/318 (34%), Gaps = 68/318 (21%) Query: 146 AVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVF 205 A+H P P P SP + P S + + G G P +S Sbjct: 251 ALHPQRPPSPHPP----PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 306 Query: 206 AQKESPGAPPAFASPPDPWGRLHRSPL-TFPAWVRPPEAARTPGSDKERPVERREPSITK 264 + PG P F PP ++PL T PA P + + P S + ++ ++P + Sbjct: 307 PLLQHPGPPQPFGLPPQ--ASQGQAPLGTSPAAAYPHTSLQLPAS--QSALQSQQPP--R 360 Query: 265 EEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAA 324 E+ P + P ++ P TP + P+ K + Sbjct: 361 EQPLPPAPLAMPHIKPPPTTPIPQL--PAPQAHKHPPHL--------------------- 397 Query: 325 AAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEEL 384 +GP + P PPP L P L PP A PP + Sbjct: 398 -----SGPSPFSMNANLP-PPPALKP---------LSSLSTHHPPS-AHPPPLQLMPQSQ 441 Query: 385 TGPGAVAAARLYGLEPAHP--LLYSRLAPPPPPAAAPGTPHLLSKTPPGA----LLGAPP 438 P + PA P L S+ PPPP + P H ++ PP A + G PP Sbjct: 442 PLPSS----------PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491 Query: 439 PLVP--APRPSSPPRGPG 454 P+ P P S+PP GPG Sbjct: 492 PITPPTCPSTSTPPAGPG 509 Score = 48.5 bits (114), Expect = 1e-05 Identities = 96/367 (26%), Positives = 132/367 (35%), Gaps = 56/367 (15%) Query: 14 RHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRL-GPVPSGLSQKGTQI 72 R P P A+P + P PP L P + PP L GP P ++ + Sbjct: 360 REQPLPPAPLAMPHIKP--PPTTPIPQL-----PAPQAHKHPPHLSGPSPFSMN---ANL 409 Query: 73 PDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQ 132 P PP KP + H H +L ++ LP P L Q Sbjct: 410 PP---PPALKPLSSLSTH---------HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 457 Query: 133 ELSHPASLFTATGAVHAAANPFTA----APGAHGPFLSP---STHIDPFGRPTSF---AS 182 L P + TG A P A PG P P ST P G TS S Sbjct: 458 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS 517 Query: 183 LAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPE 242 AA S G+ G S + + + P SPP P RSP P V P Sbjct: 518 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE--SPPPP----PRSPSPEPTVVDTPS 571 Query: 243 AARTPGSDKERPVERREPSITKEEKD-RDLPFSRPQLRVSPATPKA-RAGEEGPRPTKES 300 A + + + ++R S + + L S+ + A KA R E+ R +E Sbjct: 572 HA-SQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 630 Query: 301 VRVKE-------ERKEEAAAAAAAAAAA--AAAAAAAATGPQGLHLLFERP-----RPPP 346 + KE ER+ EA AA A+++A + +GP + FE P PP Sbjct: 631 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPP 690 Query: 347 FLGPSPP 353 ++GP P Sbjct: 691 YIGPDTP 697 Score = 38.9 bits (89), Expect = 0.010 Identities = 62/250 (24%), Positives = 80/250 (32%), Gaps = 35/250 (14%) Query: 212 GAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDL 271 G PA +S P +L T A PP+ + T +P P + Sbjct: 192 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP--VPHTHIQQA 249 Query: 272 PFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATG 331 P PQ SP P P P + + +A +A + A G Sbjct: 250 PALHPQRPPSPHPPP----HPSPHPPLQPL---------TGSAGQPSAPSHAQPPLHGQG 296 Query: 332 PQGLHLL-----FERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTG 386 P G H L + P PP G PP G L P A P + + Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFG-LPPQASQGQAP---LGTSPAAAYPHTSLQLPASQSA 352 Query: 387 PGAVAAARLYGLEPAHPLLYSRLAPPPP--------PAAAPGTPHLLSKTPPGALLGAPP 438 + R L PA PL + PPP P A PHL +P PP Sbjct: 353 LQSQQPPREQPLPPA-PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 411 Query: 439 PLVPAPRPSS 448 P PA +P S Sbjct: 412 P--PALKPLS 419 Score = 30.4 bits (67), Expect = 3.5 Identities = 48/222 (21%), Positives = 74/222 (33%), Gaps = 23/222 (10%) Query: 241 PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES 300 P AA T +D + ++ KEE L ++ Q A EE R + + Sbjct: 60 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE-----KVASDTEEADRTSSKK 114 Query: 301 VRVKE-ERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGF 359 + +E R + ++ + + ++ P+ + R P PSP D + Sbjct: 115 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ-DNRSTSPSI--PSPQDNESDS 171 Query: 360 ----------LEPTWLAAPPRLARPPRFYEAGE-ELTGPGAVAAARLYGLEPAHPLLYSR 408 +P L AP + P G +L PG +A P + Sbjct: 172 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---PPQGSPTAS 228 Query: 409 LAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPP 450 AP P A PH + P PP P P PS P Sbjct: 229 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHP 270 Score = 30.4 bits (67), Expect = 3.5 Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 412 PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP----APRPSSPPRGPGP 455 P P +A PGTP L + P + PP P AP P P P Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVP 242 Score = 29.3 bits (64), Expect = 7.8 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 9 MEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQK 68 + L H+P +A PP + +P P S G Q ++ P PP P P+GL Q Sbjct: 418 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--PPASHP-PTGLHQV 474 Query: 69 GTQIP 73 Q P Sbjct: 475 APQPP 479 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 51.2 bits (121), Expect = 2e-06 Identities = 77/318 (24%), Positives = 111/318 (34%), Gaps = 68/318 (21%) Query: 146 AVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVF 205 A+H P P P SP + P S + + G G P +S Sbjct: 805 ALHPQRPPSPHPP----PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860 Query: 206 AQKESPGAPPAFASPPDPWGRLHRSPL-TFPAWVRPPEAARTPGSDKERPVERREPSITK 264 + PG P F PP ++PL T PA P + + P S + ++ ++P + Sbjct: 861 PLLQHPGPPQPFGLPPQ--ASQGQAPLGTSPAAAYPHTSLQLPAS--QSALQSQQPP--R 914 Query: 265 EEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAA 324 E+ P + P ++ P TP + P+ K + Sbjct: 915 EQPLPPAPLAMPHIKPPPTTPIPQL--PAPQAHKHPPHL--------------------- 951 Query: 325 AAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEEL 384 +GP + P PPP L P L PP A PP + Sbjct: 952 -----SGPSPFSMNANLP-PPPALKP---------LSSLSTHHPPS-AHPPPLQLMPQSQ 995 Query: 385 TGPGAVAAARLYGLEPAHP--LLYSRLAPPPPPAAAPGTPHLLSKTPPGA----LLGAPP 438 P + PA P L S+ PPPP + P H ++ PP A + G PP Sbjct: 996 PLPSS----------PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045 Query: 439 PLVP--APRPSSPPRGPG 454 P+ P P S+PP GPG Sbjct: 1046 PITPPTCPSTSTPPAGPG 1063 Score = 48.5 bits (114), Expect = 1e-05 Identities = 96/367 (26%), Positives = 132/367 (35%), Gaps = 56/367 (15%) Query: 14 RHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRL-GPVPSGLSQKGTQI 72 R P P A+P + P PP L P + PP L GP P ++ + Sbjct: 914 REQPLPPAPLAMPHIKP--PPTTPIPQL-----PAPQAHKHPPHLSGPSPFSMN---ANL 963 Query: 73 PDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQ 132 P PP KP + H H +L ++ LP P L Q Sbjct: 964 PP---PPALKPLSSLSTH---------HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 1011 Query: 133 ELSHPASLFTATGAVHAAANPFTA----APGAHGPFLSP---STHIDPFGRPTSF---AS 182 L P + TG A P A PG P P ST P G TS S Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS 1071 Query: 183 LAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPE 242 AA S G+ G S + + + P SPP P RSP P V P Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE--SPPPP----PRSPSPEPTVVDTPS 1125 Query: 243 AARTPGSDKERPVERREPSITKEEKD-RDLPFSRPQLRVSPATPKA-RAGEEGPRPTKES 300 A + + + ++R S + + L S+ + A KA R E+ R +E Sbjct: 1126 HA-SQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 1184 Query: 301 VRVKE-------ERKEEAAAAAAAAAAA--AAAAAAAATGPQGLHLLFERP-----RPPP 346 + KE ER+ EA AA A+++A + +GP + FE P PP Sbjct: 1185 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPP 1244 Query: 347 FLGPSPP 353 ++GP P Sbjct: 1245 YIGPDTP 1251 Score = 38.9 bits (89), Expect = 0.010 Identities = 62/250 (24%), Positives = 80/250 (32%), Gaps = 35/250 (14%) Query: 212 GAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDL 271 G PA +S P +L T A PP+ + T +P P + Sbjct: 746 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP--VPHTHIQQA 803 Query: 272 PFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATG 331 P PQ SP P P P + + +A +A + A G Sbjct: 804 PALHPQRPPSPHPPP----HPSPHPPLQPL---------TGSAGQPSAPSHAQPPLHGQG 850 Query: 332 PQGLHLL-----FERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTG 386 P G H L + P PP G PP G L P A P + + Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFG-LPPQASQGQAP---LGTSPAAAYPHTSLQLPASQSA 906 Query: 387 PGAVAAARLYGLEPAHPLLYSRLAPPPP--------PAAAPGTPHLLSKTPPGALLGAPP 438 + R L PA PL + PPP P A PHL +P PP Sbjct: 907 LQSQQPPREQPLPPA-PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 965 Query: 439 PLVPAPRPSS 448 P PA +P S Sbjct: 966 P--PALKPLS 973 Score = 30.4 bits (67), Expect = 3.5 Identities = 48/222 (21%), Positives = 74/222 (33%), Gaps = 23/222 (10%) Query: 241 PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES 300 P AA T +D + ++ KEE L ++ Q A EE R + + Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE-----KVASDTEEADRTSSKK 668 Query: 301 VRVKE-ERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGF 359 + +E R + ++ + + ++ P+ + R P PSP D + Sbjct: 669 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ-DNRSTSPSI--PSPQDNESDS 725 Query: 360 ----------LEPTWLAAPPRLARPPRFYEAGE-ELTGPGAVAAARLYGLEPAHPLLYSR 408 +P L AP + P G +L PG +A P + Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---PPQGSPTAS 782 Query: 409 LAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPP 450 AP P A PH + P PP P P PS P Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHP 824 Score = 30.4 bits (67), Expect = 3.5 Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 412 PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP----APRPSSPPRGPGP 455 P P +A PGTP L + P + PP P AP P P P Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVP 796 Score = 29.3 bits (64), Expect = 7.8 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 9 MEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQK 68 + L H+P +A PP + +P P S G Q ++ P PP P P+GL Q Sbjct: 972 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--PPASHP-PTGLHQV 1028 Query: 69 GTQIP 73 Q P Sbjct: 1029 APQPP 1033 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 51.2 bits (121), Expect = 2e-06 Identities = 77/318 (24%), Positives = 111/318 (34%), Gaps = 68/318 (21%) Query: 146 AVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVF 205 A+H P P P SP + P S + + G G P +S Sbjct: 805 ALHPQRPPSPHPP----PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860 Query: 206 AQKESPGAPPAFASPPDPWGRLHRSPL-TFPAWVRPPEAARTPGSDKERPVERREPSITK 264 + PG P F PP ++PL T PA P + + P S + ++ ++P + Sbjct: 861 PLLQHPGPPQPFGLPPQ--ASQGQAPLGTSPAAAYPHTSLQLPAS--QSALQSQQPP--R 914 Query: 265 EEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAA 324 E+ P + P ++ P TP + P+ K + Sbjct: 915 EQPLPPAPLAMPHIKPPPTTPIPQL--PAPQAHKHPPHL--------------------- 951 Query: 325 AAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEEL 384 +GP + P PPP L P L PP A PP + Sbjct: 952 -----SGPSPFSMNANLP-PPPALKP---------LSSLSTHHPPS-AHPPPLQLMPQSQ 995 Query: 385 TGPGAVAAARLYGLEPAHP--LLYSRLAPPPPPAAAPGTPHLLSKTPPGA----LLGAPP 438 P + PA P L S+ PPPP + P H ++ PP A + G PP Sbjct: 996 PLPSS----------PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045 Query: 439 PLVP--APRPSSPPRGPG 454 P+ P P S+PP GPG Sbjct: 1046 PITPPTCPSTSTPPAGPG 1063 Score = 48.5 bits (114), Expect = 1e-05 Identities = 96/367 (26%), Positives = 132/367 (35%), Gaps = 56/367 (15%) Query: 14 RHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRL-GPVPSGLSQKGTQI 72 R P P A+P + P PP L P + PP L GP P ++ + Sbjct: 914 REQPLPPAPLAMPHIKP--PPTTPIPQL-----PAPQAHKHPPHLSGPSPFSMN---ANL 963 Query: 73 PDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQ 132 P PP KP + H H +L ++ LP P L Q Sbjct: 964 PP---PPALKPLSSLSTH---------HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 1011 Query: 133 ELSHPASLFTATGAVHAAANPFTA----APGAHGPFLSP---STHIDPFGRPTSF---AS 182 L P + TG A P A PG P P ST P G TS S Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS 1071 Query: 183 LAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPE 242 AA S G+ G S + + + P SPP P RSP P V P Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE--SPPPP----PRSPSPEPTVVDTPS 1125 Query: 243 AARTPGSDKERPVERREPSITKEEKD-RDLPFSRPQLRVSPATPKA-RAGEEGPRPTKES 300 A + + + ++R S + + L S+ + A KA R E+ R +E Sbjct: 1126 HA-SQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 1184 Query: 301 VRVKE-------ERKEEAAAAAAAAAAA--AAAAAAAATGPQGLHLLFERP-----RPPP 346 + KE ER+ EA AA A+++A + +GP + FE P PP Sbjct: 1185 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPP 1244 Query: 347 FLGPSPP 353 ++GP P Sbjct: 1245 YIGPDTP 1251 Score = 38.9 bits (89), Expect = 0.010 Identities = 62/250 (24%), Positives = 80/250 (32%), Gaps = 35/250 (14%) Query: 212 GAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDL 271 G PA +S P +L T A PP+ + T +P P + Sbjct: 746 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP--VPHTHIQQA 803 Query: 272 PFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATG 331 P PQ SP P P P + + +A +A + A G Sbjct: 804 PALHPQRPPSPHPPP----HPSPHPPLQPL---------TGSAGQPSAPSHAQPPLHGQG 850 Query: 332 PQGLHLL-----FERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTG 386 P G H L + P PP G PP G L P A P + + Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFG-LPPQASQGQAP---LGTSPAAAYPHTSLQLPASQSA 906 Query: 387 PGAVAAARLYGLEPAHPLLYSRLAPPPP--------PAAAPGTPHLLSKTPPGALLGAPP 438 + R L PA PL + PPP P A PHL +P PP Sbjct: 907 LQSQQPPREQPLPPA-PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 965 Query: 439 PLVPAPRPSS 448 P PA +P S Sbjct: 966 P--PALKPLS 973 Score = 30.4 bits (67), Expect = 3.5 Identities = 48/222 (21%), Positives = 74/222 (33%), Gaps = 23/222 (10%) Query: 241 PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES 300 P AA T +D + ++ KEE L ++ Q A EE R + + Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE-----KVASDTEEADRTSSKK 668 Query: 301 VRVKE-ERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGF 359 + +E R + ++ + + ++ P+ + R P PSP D + Sbjct: 669 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ-DNRSTSPSI--PSPQDNESDS 725 Query: 360 ----------LEPTWLAAPPRLARPPRFYEAGE-ELTGPGAVAAARLYGLEPAHPLLYSR 408 +P L AP + P G +L PG +A P + Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---PPQGSPTAS 782 Query: 409 LAPPPPPAAAPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPP 450 AP P A PH + P PP P P PS P Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHP 824 Score = 30.4 bits (67), Expect = 3.5 Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 412 PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP----APRPSSPPRGPGP 455 P P +A PGTP L + P + PP P AP P P P Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVP 796 Score = 29.3 bits (64), Expect = 7.8 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 9 MEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGPVPSGLSQK 68 + L H+P +A PP + +P P S G Q ++ P PP P P+GL Q Sbjct: 972 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--PPASHP-PTGLHQV 1028 Query: 69 GTQIP 73 Q P Sbjct: 1029 APQPP 1033 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.136 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,893,446 Number of Sequences: 37866 Number of extensions: 2101887 Number of successful extensions: 27538 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 404 Number of HSP's successfully gapped in prelim test: 1413 Number of HSP's that attempted gapping in prelim test: 13815 Number of HSP's gapped (non-prelim): 9283 length of query: 460 length of database: 18,247,518 effective HSP length: 106 effective length of query: 354 effective length of database: 14,233,722 effective search space: 5038737588 effective search space used: 5038737588 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.