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Search of human proteins with 157266285
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
(670 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157266285 hypothetical protein LOC728936 [Homo sapiens] 1352 0.0
gi|29789405 hypothetical protein LOC284565 [Homo sapiens] 1341 0.0
gi|83415174 hypothetical protein LOC400818 [Homo sapiens] 1288 0.0
gi|92110019 hypothetical protein LOC55672 [Homo sapiens] 1271 0.0
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] 1214 0.0
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap... 1211 0.0
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ... 1207 0.0
gi|7657017 hypothetical protein LOC25832 [Homo sapiens] 1087 0.0
gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 998 0.0
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 998 0.0
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi... 818 0.0
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ... 530 e-150
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1... 483 e-136
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2... 479 e-135
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap... 479 e-135
gi|114158664 hypothetical protein LOC343505 [Homo sapiens] 451 e-126
gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ... 224 2e-58
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami... 119 9e-27
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami... 116 6e-26
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6... 116 6e-26
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6... 114 4e-25
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 80 5e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 66 1e-10
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 62 2e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 2e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 2e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 2e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 2e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 54 5e-07
gi|148746195 trichohyalin [Homo sapiens] 52 2e-06
>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
Length = 670
Score = 1352 bits (3498), Expect = 0.0
Identities = 670/670 (100%), Positives = 670/670 (100%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEE 600
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEE
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEE 600
Query: 601 PEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660
PEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL
Sbjct: 601 PEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660
Query: 661 VFQMGVIFPQ 670
VFQMGVIFPQ
Sbjct: 661 VFQMGVIFPQ 670
>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
Length = 670
Score = 1341 bits (3470), Expect = 0.0
Identities = 666/670 (99%), Positives = 666/670 (99%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL VDR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEE 600
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRL GVLMEVEE
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEE 600
Query: 601 PEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660
PEVLQDSLDRCYST SMYFE PDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL
Sbjct: 601 PEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660
Query: 661 VFQMGVIFPQ 670
VFQMGVIFPQ
Sbjct: 661 VFQMGVIFPQ 670
>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
Length = 942
Score = 1288 bits (3333), Expect = 0.0
Identities = 646/671 (96%), Positives = 655/671 (97%), Gaps = 1/671 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLAN+Q KYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKY 331
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDD+EDVQVEVAE
Sbjct: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST SIP
Sbjct: 512 IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIP 571
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 572 PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 632 LQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 691
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSL R YSTPS Y ELPDLGQPYSSAVYSLEEQYLGLALD+DR
Sbjct: 692 PRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDR 751
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFY
Sbjct: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFY 811
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVE 599
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRLNGVLMEVE
Sbjct: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 871
Query: 600 EPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLH 659
EPEVLQDSLD CYST SMYFELPDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLH
Sbjct: 872 EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH 931
Query: 660 LVFQMGVIFPQ 670
LVFQM VIFPQ
Sbjct: 932 LVFQMEVIFPQ 942
Score = 541 bits (1393), Expect = e-153
Identities = 345/700 (49%), Positives = 432/700 (61%), Gaps = 78/700 (11%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CFLTQLAGFLANRQKKYKY
Sbjct: 1 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KV +S APRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPHK KITFEED+V+STL
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
Query: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 289
+ SSH E +DA++I+P + ++ GP+S N+ E E+ PQ +
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
Query: 290 WDEGYSTLSIPPE----MLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 342
++ ++ + LA + + + EE + + + R +++ ++ ++
Sbjct: 301 -EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
Query: 343 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ-- 394
A R + L+ +E E+ L++ D S L +P +S L++
Sbjct: 360 AEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQL 419
Query: 395 -----------QRVGLAIDMDEIEKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 441
Q++ D D+ E Q E+ Q S P RE+ +E EV +DSL+
Sbjct: 420 AEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
Query: 442 RCYSTPSDYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR---------IKKDQEE 487
C T S+ D QP+ + EE +G + V+R + D EE
Sbjct: 477 ECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536
Query: 488 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 547
EE++GP P R L E E EV Q+S D YSTPS E S + Y S+F++LEE+ V
Sbjct: 537 EEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQV 593
Query: 548 GFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDS 607
++D+G + R + + ED PRL+ L++ + PEVLQDS
Sbjct: 594 CMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS 635
Query: 608 LDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
L RCYST S EL DS Q YRS FY E++ + A+ +D
Sbjct: 636 LYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
Length = 1214
Score = 1271 bits (3290), Expect = 0.0
Identities = 635/672 (94%), Positives = 649/672 (96%), Gaps = 2/672 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILE+NEKLRPQLAEKKQQFRNLKEKCF+TQLA FLAN+Q KYKY
Sbjct: 543 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY 602
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK +LRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 603 EECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 662
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRL Q L QKLSPENDND DEDVQVEVAE
Sbjct: 663 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDNDHDEDVQVEVAE 722
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 723 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 783 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 842
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASYQSYS TFHSLEEQQVCMAVDIG HRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 843 PEMLASYQSYSGTFHSLEEQQVCMAVDIGGHRWDQVKKEDQEATGPRLSRELLDEKGPEV 902
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQRVG A+DMDEIEKYQEVEEDQDPSC
Sbjct: 903 LQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSC 962
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPY SAVYSLEEQYLGLALDVDR
Sbjct: 963 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDR 1022
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGSSFY
Sbjct: 1023 IKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFY 1082
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRS-KKKRRRGRKEGEDD-NPPCPRLNGVLMEV 598
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRS KK+RRRGRKEGE+D NPPCPRL+G+LMEV
Sbjct: 1083 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEV 1142
Query: 599 EEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSL 658
EEPEVLQDSLDRCYST SMYFELPDSFQHYRSVFYSFEE+HISFAL VDNRF TL TSL
Sbjct: 1143 EEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNRFLTLMGTSL 1202
Query: 659 HLVFQMGVIFPQ 670
HLVFQMGVIFPQ
Sbjct: 1203 HLVFQMGVIFPQ 1214
Score = 549 bits (1415), Expect = e-156
Identities = 350/699 (50%), Positives = 431/699 (61%), Gaps = 76/699 (10%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILE+NEKLRPQLAEKKQQFRNLKEKCF+TQLAGFLAN+Q KYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKY 331
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EEC+DLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 332 EECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 391
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 392 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 451
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK ITFEEDKV+S L
Sbjct: 452 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511
Query: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQ-E 288
+ SSH E +DAV+I+P + ++ GP+S N+ E E+ PQ
Sbjct: 512 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 571
Query: 289 SWDEGYSTLSIP--PEMLASYQSYSSTFHSLEE-QQVCMAVDIGRHRWDQVKKEDQ--EA 343
+ + L LA + + + EE + + +V ++ + K +Q +A
Sbjct: 572 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQA 631
Query: 344 TGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ-- 395
R + L+ +E E+ L++ D S L +P +S L++Q
Sbjct: 632 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 691
Query: 396 ---RVGLAI----------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 442
R+ + D DE + + E+ Q S P RE+ +E EV +DSL+
Sbjct: 692 EGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEE 748
Query: 443 CYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL--------------DVDRIKKDQEEE 488
C T S+ D QP+ + EE + L + + D EEE
Sbjct: 749 CAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEE 808
Query: 489 EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 548
E++GP P R L E E EV Q+S D YST S E S Q Y +F++LEE+ V
Sbjct: 809 EEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVC 865
Query: 549 FSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSL 608
++D+G G R + ++ ED PRL+ L++ + PEVLQDSL
Sbjct: 866 MAVDIG------------GHRWDQVKK------EDQEATGPRLSRELLDEKGPEVLQDSL 907
Query: 609 DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
DRCYST S Y EL DS Q YRS FY E++ + +AL +D
Sbjct: 908 DRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMD 946
Score = 465 bits (1196), Expect = e-131
Identities = 285/524 (54%), Positives = 343/524 (65%), Gaps = 41/524 (7%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGP SSEKAE NILEINEKLRPQLAE KQQFRNLKEKCF+TQLAGFLANRQKKYKY
Sbjct: 1 MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK ITFEEDKV+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240
Query: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQ-E 288
+ SSH E +DAV+I+P + ++ GP+S N+ E E+ PQ
Sbjct: 241 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 300
Query: 289 SWDEGYSTLSIP--PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQEA 343
+ + L LA + + + EE + + + R +++ ++ ++A
Sbjct: 301 EKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQA 360
Query: 344 TGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 397
R + L+ +E E+ L++ D S L +P +S L++Q
Sbjct: 361 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 420
Query: 398 -GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 442
G + D DE + +E E+ + S P RE+ +E +V +DSL+
Sbjct: 421 EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAP---REVQKAEESKVPEDSLEE 477
Query: 443 CYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQE 486
C T S+ D QP+ + + EE + AL VDR E
Sbjct: 478 CAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDE 521
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/53 (33%), Positives = 31/53 (58%)
Query: 595 LMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
+ + EE +V +DSL+ C T S DS Q ++++ +FEE+ ++ L VD
Sbjct: 191 VQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVVD 243
Score = 33.5 bits (75), Expect = 0.65
Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 13/158 (8%)
Query: 404 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463
+E+ +Y+ + Q+ +L +L + ++ + + TP + PD Q
Sbjct: 90 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDE----PDKSQGQDLQ 145
Query: 464 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVLQDSL 515
E L L V ++ + +E+ED+ RE+ + E +V +DSL
Sbjct: 146 EQLAEGCRLAQHL-VQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSL 204
Query: 516 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 553
+ C T S+ DS QP+ + EE V +L V
Sbjct: 205 EECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVV 242
>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
Length = 3628
Score = 1214 bits (3141), Expect = 0.0
Identities = 606/648 (93%), Positives = 622/648 (95%), Gaps = 1/648 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL+GFLAN+QKKYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQL+EKLREGRDAS
Sbjct: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 392 RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPH+KTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 571
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 572 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
QDS DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 632 FQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSC 691
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR
Sbjct: 692 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 751
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 811
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVE 599
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +
Sbjct: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 871
Query: 600 EPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
PEVLQDSLDRCYST S EL DS Q YRS FY E++ + FA+ +D
Sbjct: 872 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMD 919
Score = 610 bits (1572), Expect = e-174
Identities = 332/505 (65%), Positives = 368/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 673 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 733 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 779 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 839 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 899 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 959 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + FA+ +D
Sbjct: 1139 DSCQPYRSAFYVLEQQRVGFAVDMD 1163
Score = 610 bits (1572), Expect = e-174
Identities = 332/505 (65%), Positives = 367/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 2443 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE V ++D+G
Sbjct: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2788
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 2789 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2848
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++H+ A+ +D
Sbjct: 2849 DSCQPYRSAFYVLEQQHVGLAVDMD 2873
Score = 608 bits (1567), Expect = e-174
Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1711 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE V ++D+G
Sbjct: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 2057 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2116
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++H+ A+ +D
Sbjct: 2117 DSCQPYRSAFYVLEQQHVGLAVDMD 2141
Score = 608 bits (1567), Expect = e-174
Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1955 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE V ++D+G
Sbjct: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 2301 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2360
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++H+ A+ +D
Sbjct: 2361 DSCQPYRSAFYVLEQQHVGLAVDMD 2385
Score = 608 bits (1567), Expect = e-174
Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 2199 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE V ++D+G
Sbjct: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 2545 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2604
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++H+ A+ +D
Sbjct: 2605 DSCQPYRSAFYVLEQQHVGLAVDMD 2629
Score = 605 bits (1559), Expect = e-173
Identities = 330/505 (65%), Positives = 367/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 2687 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3032
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + P+VLQDSLDRCYST S EL
Sbjct: 3033 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELC 3092
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 3093 DSCQPYRSAFYVLEQQRVGLAVDMD 3117
Score = 604 bits (1557), Expect = e-173
Identities = 330/505 (65%), Positives = 367/505 (72%), Gaps = 38/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL C T S D QP+
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L D I + + ++EE+E++ P PR L E E
Sbjct: 1465 SAVYSLEEQYLGLAL----------DVDRI--KKDQEEEEDEDQDPPCPRLSRELLEVVE 1512
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE V ++D+G
Sbjct: 1513 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1572
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1573 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1632
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1633 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1692
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 1693 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1752
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 1812
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 1813 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1872
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++H+ A+ +D
Sbjct: 1873 DSCQPYRSAFYVLEQQHVGLAVDMD 1897
Score = 603 bits (1556), Expect = e-172
Identities = 341/579 (58%), Positives = 402/579 (69%), Gaps = 36/579 (6%)
Query: 90 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
+E+ +Y+ + Q+ +L +L + ++ + + TP +P S
Sbjct: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
Query: 141 GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197
L+EQ G L ++K D +++ED Q PR E+ + E
Sbjct: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977
Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
EV +DSL+ C T S+ DS QP+ + EE V +L + +
Sbjct: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037
Query: 258 ENESD-----DEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQS 309
++ + E EE++ P PR +E +E+ P Q+S D YST S E+ S Q
Sbjct: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097
Query: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369
Y S F+ LE+Q+V +AVD+ Q +EDQ+ + PRLSRELLDEK PEVLQDSLDRCY
Sbjct: 3098 YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCY 3157
Query: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429
STPSGCLEL DSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 3158 STPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3217
Query: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 489
EKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 3218 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277
Query: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549
DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 3278 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3337
Query: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSL 608
SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSL
Sbjct: 3338 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3397
Query: 609 DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
DRCYST S EL DS Q YRS FY E++H+ A+ +D
Sbjct: 3398 DRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
Score = 601 bits (1550), Expect = e-172
Identities = 328/505 (64%), Positives = 365/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 917 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 977 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGMAVDMD 1407
Score = 595 bits (1535), Expect = e-170
Identities = 327/507 (64%), Positives = 366/507 (72%), Gaps = 42/507 (8%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D+EEEE++ P PR L E
Sbjct: 1221 SAVYSLEEQYLGLALD--------------VDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVG+A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL+RC
Sbjct: 1387 PYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRC 1446
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE--EDQGPPCPRLSRE 501
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE EDQ PPCPRLSRE
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRE 1506
Query: 502 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 561
LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGK
Sbjct: 1507 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK 1566
Query: 562 GKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFE 620
GKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S E
Sbjct: 1567 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1626
Query: 621 LPDSFQHYRSVFYSFEEEHISFALYVD 647
L DS Q YRS FY E++H+ A+ +D
Sbjct: 1627 LTDSCQPYRSAFYVLEQQHVGLAVDMD 1653
Score = 574 bits (1479), Expect = e-163
Identities = 319/528 (60%), Positives = 372/528 (70%), Gaps = 40/528 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ + EV +DSL+ C T S DS QP++
Sbjct: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
E+ +V + + E E E EE++ P PR L + +E
Sbjct: 3175 SAFYILEQQRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 342
EV Q+S D YST S E+ Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ
Sbjct: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280
Query: 343 ATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAID 402
PRLSRELL+ EPEVLQDSLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D
Sbjct: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340
Query: 403 MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
+ EIEK +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRC
Sbjct: 3341 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 3400
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS LEL D QPY SA Y LE+Q++GLA+D+D I+K QE EEDQ P CPRLSRELL
Sbjct: 3401 YSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3460
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
+ EPEVLQDSLDRCYSTPS LE PD QPY S+ Y+LEE+++G +LDV +IEKKGKGK
Sbjct: 3461 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGK 3520
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRLNGVLMEVEE EVLQDSLDRCYST SMYFELP
Sbjct: 3521 KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELP 3580
Query: 623 DSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 670
DSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 3581 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628
Score = 547 bits (1410), Expect = e-155
Identities = 349/711 (49%), Positives = 421/711 (59%), Gaps = 100/711 (14%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGP SSEKAEMNILEINE LRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1 MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK KITFEED+V+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 298
+ SSH E +DA++I+P GP S P S + L
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
Query: 299 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIG--------RHRWDQVK------------- 337
I ++ F +L+E+ C + ++++++ K
Sbjct: 291 INEKLRPQLAEKKQQFRNLKEK--CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQF 348
Query: 338 KEDQEATGPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGCLELTDSCQPY 385
KE++ A + + EL E+E E L++ D S L +P
Sbjct: 349 KEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPD 408
Query: 386 RSAFYVLEQQRV-GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 430
+S L++Q G + D DE + + E+ Q S P RE+
Sbjct: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKA 465
Query: 431 KEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL-------------- 476
+E EV +DSL+ C T S+ D QP+ + EE + L
Sbjct: 466 EEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525
Query: 477 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536
+ + D EEEE++GP P R L E E EV Q+S D YST S E S Q Y
Sbjct: 526 IIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS 582
Query: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLM 596
S+F++LEE+ V ++D+G + R + + ED PRL+ L+
Sbjct: 583 STFHSLEEQQVCMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELL 624
Query: 597 EVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
+ + PEV QDS DRCYST S EL DS Q YRS FY E++ + A+ +D
Sbjct: 625 DEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMD 675
>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
sapiens]
Length = 3815
Score = 1211 bits (3134), Expect = 0.0
Identities = 603/648 (93%), Positives = 621/648 (95%), Gaps = 1/648 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRNLKE+CF+TQLAGFLAN+QKKYKY
Sbjct: 21 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 80
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 81 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 140
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVE+AE
Sbjct: 141 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 200
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 201 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 260
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 261 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 320
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 321 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 380
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 381 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 440
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR
Sbjct: 441 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 500
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 501 TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 560
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVE 599
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +
Sbjct: 561 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 620
Query: 600 EPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
PEVLQDSLDRCYST S EL DS Q YRS FY E++ + A+ +D
Sbjct: 621 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 668
Score = 616 bits (1588), Expect = e-176
Identities = 335/505 (66%), Positives = 369/505 (73%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 422 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 481
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 482 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 527
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 528 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 587
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 588 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 647
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 648 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 707
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 708 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 767
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 768 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 827
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELP
Sbjct: 828 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 887
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
D Q Y S YS EE+++ AL VD
Sbjct: 888 DLGQPYSSAVYSLEEQYLGLALDVD 912
Score = 616 bits (1588), Expect = e-176
Identities = 335/505 (66%), Positives = 369/505 (73%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 2149 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2208
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 2209 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2254
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 2255 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2314
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2315 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2374
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2375 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2434
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2435 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2494
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2495 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2554
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELP
Sbjct: 2555 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2614
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
D Q Y S YS EE+++ AL VD
Sbjct: 2615 DLGQPYSSAVYSLEEQYLGLALDVD 2639
Score = 611 bits (1576), Expect = e-175
Identities = 328/482 (68%), Positives = 359/482 (74%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ +E EV +DSL+ C T S D QP+ + EE + L
Sbjct: 2585 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 2637
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ + D EEEE++GP PR L E E EV Q+S D YST S E
Sbjct: 2638 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 2690
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
S Q Y S+F++LEE+ V ++D+G R R + +EDQ P
Sbjct: 2691 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 2750
Query: 347 RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
RLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 2751 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 2810
Query: 407 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2811 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2870
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2871 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2930
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 2931 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2990
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++ AL
Sbjct: 2991 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3050
Query: 646 VD 647
VD
Sbjct: 3051 VD 3052
Score = 606 bits (1563), Expect = e-173
Identities = 325/494 (65%), Positives = 362/494 (73%), Gaps = 37/494 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ +E EV +DSL+ C T S D QP+ + EE + L
Sbjct: 3336 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 3388
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ + D EEEE++GP PR L E E EV Q+S D YST S E
Sbjct: 3389 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3441
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
S Q Y S+F++LEE+ V ++D+G R R + +EDQ P
Sbjct: 3442 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3501
Query: 347 RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
RLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 3502 RLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 3561
Query: 407 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 3562 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3621
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3622 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3681
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 3682 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3741
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ + A+
Sbjct: 3742 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3801
Query: 646 VDNRFFTLTVTSLH 659
+D + ++ V +H
Sbjct: 3802 MDGEYLSMKVIRIH 3815
Score = 604 bits (1558), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1661 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1720
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1721 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1766
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1767 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1826
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1827 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1886
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1887 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1946
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1947 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2006
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2007 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2066
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL
Sbjct: 2067 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2126
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 2127 DSCQPYRSAFYVLEQQRVGLAVDMD 2151
Score = 604 bits (1558), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1905 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1964
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1965 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2010
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 2011 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2070
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2071 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2130
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2131 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2190
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2191 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2250
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2251 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2310
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 2311 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2370
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 2371 DSCQPYRSAFYVLEQQRVGLAVDMD 2395
Score = 603 bits (1556), Expect = e-172
Identities = 324/482 (67%), Positives = 357/482 (74%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ +E EV +DSL+ C T S D QP+ + EE + L
Sbjct: 1440 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 1492
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ + D EEEE++GP PR L E E EV Q+S D YST S E
Sbjct: 1493 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1545
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
S Q Y S+F++LEE+ V ++D+G R R + +EDQ P
Sbjct: 1546 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 1605
Query: 347 RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
RLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 1606 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 1665
Query: 407 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 1666 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 1725
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 1726 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 1785
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 1786 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1845
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ + A+
Sbjct: 1846 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 1905
Query: 646 VD 647
+D
Sbjct: 1906 MD 1907
Score = 591 bits (1523), Expect = e-169
Identities = 325/505 (64%), Positives = 362/505 (71%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 666 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 725
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 726 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 771
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 772 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 831
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEKEPEVLQDSLDRCYSTPSG LEL D Q
Sbjct: 832 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 891
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PY SA Y LE+Q +GLA+D+DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 892 PYSSAVYSLEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 951
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 952 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1011
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1012 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1071
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELP
Sbjct: 1072 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1131
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
D Q Y S YS EE+++ AL VD
Sbjct: 1132 DLGQPYSSAVYSLEEQYLGLALDVD 1156
Score = 564 bits (1454), Expect = e-161
Identities = 307/482 (63%), Positives = 347/482 (71%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ +E EV +DSL+ C T S D QP+ + EE + L
Sbjct: 858 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 910
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ E E E EE++ P PR L + +E EV Q+S D YST S E+
Sbjct: 911 -------VDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 963
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEVLQDSL
Sbjct: 964 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 1023
Query: 366 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
DRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 1024 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1083
Query: 410 ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 1084 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 1143
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 1144 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 1203
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 1204 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1263
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++ AL
Sbjct: 1264 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 1323
Query: 646 VD 647
VD
Sbjct: 1324 VD 1325
Score = 563 bits (1451), Expect = e-160
Identities = 328/604 (54%), Positives = 392/604 (64%), Gaps = 45/604 (7%)
Query: 79 EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTP----D 134
EE+ +E+ +Y+ + Q+ +L +L + ++ + + TP +
Sbjct: 901 EEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 960
Query: 135 EPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EM 191
PD Q E Q+L L + D E+ E+ Q PR E+
Sbjct: 961 LPDLGQPYSSAVYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSREL 1010
Query: 192 QKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWED 251
+ E EV +DSL+ C T S+ DS QP+ + EE V +L + +
Sbjct: 1011 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKG 1070
Query: 252 AVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEM 303
++ + E EE++ P PR L + +E EV Q+S D YST S E+
Sbjct: 1071 KKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 1130
Query: 304 LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQD 363
Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEVLQD
Sbjct: 1131 PDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 1190
Query: 364 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY-------------- 409
SLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 1191 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1250
Query: 410 -----QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAV 464
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAV
Sbjct: 1251 RRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 1310
Query: 465 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 524
YSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 1311 YSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 1370
Query: 525 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD 584
CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D
Sbjct: 1371 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1430
Query: 585 -NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFA 643
NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++ A
Sbjct: 1431 QNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 1490
Query: 644 LYVD 647
L VD
Sbjct: 1491 LDVD 1494
Score = 563 bits (1451), Expect = e-160
Identities = 306/482 (63%), Positives = 348/482 (72%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + EV +DSL+ C T S DS QP++ E+ +V +
Sbjct: 2754 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2806
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ E E E EE++ P PR L + +E EV Q+S D YST S E+
Sbjct: 2807 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2859
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEVLQDSL
Sbjct: 2860 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2919
Query: 366 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
DRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 2920 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2979
Query: 410 ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2980 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3039
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3040 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3099
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 3100 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3159
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++ AL
Sbjct: 3160 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3219
Query: 646 VD 647
VD
Sbjct: 3220 VD 3221
Score = 562 bits (1449), Expect = e-160
Identities = 307/487 (63%), Positives = 352/487 (72%), Gaps = 28/487 (5%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + E EV +DSL+ C T S+ DS QP+ + EE V +L +
Sbjct: 2904 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2963
Query: 249 WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
+ ++ + E EE++ P PR L + +E EV Q+S D YST S
Sbjct: 2964 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3023
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
E+ Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEV
Sbjct: 3024 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3083
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
LQDSLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 3084 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3143
Query: 410 --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 3144 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3203
Query: 462 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3204 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3263
Query: 522 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3264 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3323
Query: 582 EDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHI 640
E+D NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++
Sbjct: 3324 EEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3383
Query: 641 SFALYVD 647
AL VD
Sbjct: 3384 GLALDVD 3390
Score = 555 bits (1431), Expect = e-158
Identities = 302/482 (62%), Positives = 346/482 (71%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + EV +DSL+ C T S DS QP++ E+ +V +
Sbjct: 2341 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2393
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ E E E EE++ P PR L + +E EV Q+S D YST S E+
Sbjct: 2394 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2446
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEVLQDSL
Sbjct: 2447 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2506
Query: 366 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
DRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 2507 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2566
Query: 410 ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2567 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2626
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2627 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2686
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 2687 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2746
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ + A+
Sbjct: 2747 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 2806
Query: 646 VD 647
+D
Sbjct: 2807 MD 2808
Score = 555 bits (1429), Expect = e-158
Identities = 303/487 (62%), Positives = 350/487 (71%), Gaps = 28/487 (5%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + E EV +DSL+ C T S+ DS QP+ + EE V +L +
Sbjct: 1177 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1236
Query: 249 WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
+ ++ + E EE++ P PR L + +E EV Q+S D YST S
Sbjct: 1237 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 1296
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
E+ Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEV
Sbjct: 1297 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 1356
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
LQDSLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 1357 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 1416
Query: 410 --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 1417 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1476
Query: 462 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 1477 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 1536
Query: 522 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 1537 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 1596
Query: 582 EDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHI 640
E+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ +
Sbjct: 1597 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 1656
Query: 641 SFALYVD 647
A+ +D
Sbjct: 1657 GLAVDMD 1663
Score = 551 bits (1419), Expect = e-157
Identities = 302/487 (62%), Positives = 349/487 (71%), Gaps = 28/487 (5%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + E EV +DSL+ C T S+ DS QP+ + EE V +L +
Sbjct: 3073 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3132
Query: 249 WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
+ ++ + E EE++ P PR L + +E EV Q+S D YST S
Sbjct: 3133 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3192
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
E+ Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEV
Sbjct: 3193 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3252
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
LQDSLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 3253 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3312
Query: 410 --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 3313 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3372
Query: 462 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3373 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3432
Query: 522 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3433 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3492
Query: 582 EDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHI 640
E+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL DS Q YRS FY E++ +
Sbjct: 3493 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRV 3552
Query: 641 SFALYVD 647
A+ +D
Sbjct: 3553 GLAVDMD 3559
>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
sapiens]
Length = 4621
Score = 1207 bits (3124), Expect = 0.0
Identities = 602/648 (92%), Positives = 620/648 (95%), Gaps = 1/648 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRNLKE+CF+TQLAGFLAN+QKKYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 331
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 332 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVE+AE
Sbjct: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 451
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPREMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 571
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 572 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 632 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 691
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR
Sbjct: 692 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 751
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 752 TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 811
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVE 599
ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +
Sbjct: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 871
Query: 600 EPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
PEVLQDSLDR YST S EL DS Q YRS FY E++ + A+ +D
Sbjct: 872 GPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 919
Score = 708 bits (1828), Expect = 0.0
Identities = 379/528 (71%), Positives = 406/528 (76%), Gaps = 40/528 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 4108 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 4167
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 4168 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 4213
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 4214 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4273
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 4274 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4333
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 4334 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4393
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 4394 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4453
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 4454 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4513
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKKKRRRGRKEGE+D NPPCPRLNGVLMEVEEPEVLQDSLD CYST SMYFELP
Sbjct: 4514 KRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELP 4573
Query: 623 DSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 670
DSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 4574 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 4621
Score = 612 bits (1578), Expect = e-175
Identities = 334/505 (66%), Positives = 368/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 2381 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2440
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 2441 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2486
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 2487 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2546
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2547 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2606
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2607 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2666
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2667 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2726
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2727 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2786
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELP
Sbjct: 2787 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2846
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
D Q Y S YS EE+++ AL VD
Sbjct: 2847 DLGQPYSSAVYSLEEQYLGLALDVD 2871
Score = 608 bits (1568), Expect = e-174
Identities = 331/505 (65%), Positives = 367/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 3376 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3435
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 3436 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3481
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 3482 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3541
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 3542 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3601
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 3602 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3661
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 3662 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3721
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 3722 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3781
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 3782 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 3841
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 3842 DSCQPYRSAFYVLEQQRVGLAVDMD 3866
Score = 608 bits (1567), Expect = e-174
Identities = 331/505 (65%), Positives = 367/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 3864 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3923
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 3924 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3969
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 3970 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4029
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 4030 RRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4089
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 4090 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4149
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 4150 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4209
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 4210 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4269
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 4270 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4329
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 4330 DSCQPYRSAFYVLEQQRVGLAVDMD 4354
Score = 606 bits (1562), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 3620 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3679
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 3680 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3725
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 3726 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3785
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 3786 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3845
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 3846 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3905
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 3906 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3965
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 3966 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4025
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D PPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 4026 KRRGRRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4085
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 4086 DSCQPYRSAFYVLEQQRVGLAVDMD 4110
Score = 604 bits (1558), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 673 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 733 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 778
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 779 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 839 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 898
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 899 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 959 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1018
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 1139 DSCQPYRSAFYVLEQQRVGLAVDMD 1163
Score = 604 bits (1558), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 917 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 977 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1022
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1143 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1262
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 1382
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGLAVDMD 1407
Score = 604 bits (1558), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1221 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1266
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1386
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1387 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1446
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1506
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1507 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1566
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL
Sbjct: 1567 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1626
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 1627 DSCQPYRSAFYVLEQQRVGLAVDMD 1651
Score = 604 bits (1558), Expect = e-173
Identities = 330/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1464
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1465 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1510
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1511 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1570
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1571 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1630
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1631 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1690
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1691 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1750
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1751 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1810
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL
Sbjct: 1811 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 1870
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 1871 DSCQPYRSAFYVLEQQRVGLAVDMD 1895
Score = 603 bits (1556), Expect = e-172
Identities = 324/482 (67%), Positives = 357/482 (74%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ +E EV +DSL+ C T S D QP+ + EE + L
Sbjct: 3155 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 3207
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ + D EEEE++GP PR L E E EV Q+S D YST S E
Sbjct: 3208 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3260
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
S Q Y S+F++LEE+ V ++D+G R R + +EDQ P
Sbjct: 3261 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3320
Query: 347 RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
RLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 3321 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 3380
Query: 407 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 3381 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3440
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3441 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3500
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 3501 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3560
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ + A+
Sbjct: 3561 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3620
Query: 646 VD 647
+D
Sbjct: 3621 MD 3622
Score = 600 bits (1548), Expect = e-171
Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1649 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1708
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1709 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1754
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1755 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1814
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 1815 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1874
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1875 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1934
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1935 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1994
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1995 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2054
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL
Sbjct: 2055 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2114
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 2115 DSCQPYRSAFYVLEQQRVGLAVDMD 2139
Score = 600 bits (1548), Expect = e-171
Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 1893 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1952
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 1953 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1998
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 1999 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2058
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2059 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2118
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2119 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2178
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2179 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2238
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2239 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2298
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL
Sbjct: 2299 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2358
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 2359 DSCQPYRSAFYVLEQQRVGLAVDMD 2383
Score = 600 bits (1548), Expect = e-171
Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)
Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S D QP+
Sbjct: 2137 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2196
Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
+ EE + L + + D EEEE++GP PR L E E
Sbjct: 2197 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2242
Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
EV Q+S D YST S E S Q Y S+F++LEE+ V ++D+G
Sbjct: 2243 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2302
Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
R R + +EDQ PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2303 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2362
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2363 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2422
Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503
YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2423 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2482
Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2483 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2542
Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622
KRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSLDR YST S EL
Sbjct: 2543 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2602
Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
DS Q YRS FY E++ + A+ +D
Sbjct: 2603 DSCQPYRSAFYVLEQQRVGLAVDMD 2627
Score = 562 bits (1449), Expect = e-160
Identities = 307/487 (63%), Positives = 352/487 (72%), Gaps = 28/487 (5%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + E EV +DSL+ C T S+ DS QP+ + EE V +L +
Sbjct: 2723 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2782
Query: 249 WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
+ ++ + E EE++ P PR L + +E EV Q+S D YST S
Sbjct: 2783 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 2842
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
E+ Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEV
Sbjct: 2843 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 2902
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
LQDSLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 2903 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 2962
Query: 410 --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 2963 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3022
Query: 462 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3023 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3082
Query: 522 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3083 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3142
Query: 582 EDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHI 640
E+D NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++
Sbjct: 3143 EEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3202
Query: 641 SFALYVD 647
AL VD
Sbjct: 3203 GLALDVD 3209
Score = 559 bits (1441), Expect = e-159
Identities = 305/482 (63%), Positives = 347/482 (71%), Gaps = 37/482 (7%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + EV +DSL+ T S DS QP++ E+ +V +
Sbjct: 2573 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2625
Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
+ E E E EE++ P PR L + +E EV Q+S D YST S E+
Sbjct: 2626 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2678
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEVLQDSL
Sbjct: 2679 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2738
Query: 366 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
DRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 2739 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2798
Query: 410 ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2799 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2858
Query: 467 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2859 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2918
Query: 527 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 2919 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2978
Query: 586 PPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALY 645
PPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++ AL
Sbjct: 2979 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3038
Query: 646 VD 647
VD
Sbjct: 3039 VD 3040
Score = 555 bits (1429), Expect = e-158
Identities = 303/487 (62%), Positives = 350/487 (71%), Gaps = 28/487 (5%)
Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
RE+ + E EV +DSL+ C T S+ DS QP+ + EE V +L +
Sbjct: 2892 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2951
Query: 249 WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
+ ++ + E EE++ P PR L + +E EV Q+S D YST S
Sbjct: 2952 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3011
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
E+ Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSRELL+ EPEV
Sbjct: 3012 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3071
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
LQDSLDRCYSTPS CLE DSCQPY S+FY LE++ VG ++D+ EIEK
Sbjct: 3072 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3131
Query: 410 --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
+E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 3132 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3191
Query: 462 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3192 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3251
Query: 522 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3252 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3311
Query: 582 EDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHI 640
E+D NPPCPRL+ L++ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ +
Sbjct: 3312 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 3371
Query: 641 SFALYVD 647
A+ +D
Sbjct: 3372 GLAVDMD 3378
Score = 541 bits (1394), Expect = e-154
Identities = 347/711 (48%), Positives = 420/711 (59%), Gaps = 100/711 (14%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CF+TQLAGFLAN+QKKY Y
Sbjct: 1 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLT DEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSSAPRE+QK EE +VPEDSLEECAITCSNSHGP DSNQPHK KITFEED+V+STL
Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 298
+ SSH E +DA++I+P GP S P S + L
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
Query: 299 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIG--------RHRWDQVK------------- 337
I ++ F +L+E+ C + ++++++ K
Sbjct: 291 INEKLHPQLAEKKQQFRNLKER--CFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQF 348
Query: 338 KEDQEATGPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGCLELTDSCQPY 385
KE++ A + + EL E+E E L++ D S L +P
Sbjct: 349 KEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPD 408
Query: 386 RSAFYVLEQQRV-GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 430
+S L++Q G + D DE + + E+ Q S P RE+
Sbjct: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAP---REMQKA 465
Query: 431 KEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL-------------- 476
+E EV +DS + C T S+ D QP+ + EE + L
Sbjct: 466 EEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525
Query: 477 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536
+ + D EEEE++GP P R L E E EV Q+S D YST S E S Q Y
Sbjct: 526 IIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS 582
Query: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLM 596
S+F++LEE+ V ++D+G + R + + ED PRL+ L+
Sbjct: 583 STFHSLEEQQVCMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELL 624
Query: 597 EVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
+ + PEVLQDSLDRCYST S EL DS Q YRS FY E++ I A+ +D
Sbjct: 625 DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMD 675
>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
Length = 921
Score = 1087 bits (2812), Expect = 0.0
Identities = 540/579 (93%), Positives = 555/579 (95%), Gaps = 1/579 (0%)
Query: 70 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 129
MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 1 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 189
LLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 61 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
Query: 190 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEW 249
EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
Query: 250 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 309
EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
Query: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369
YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEK PEVLQDSLDRCY
Sbjct: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
Query: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429
STPSGCLELTDSCQPYRSAFYVLEQQRVGLA++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
Query: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 489
EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
Query: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549
DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
Query: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSL 608
SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+ L++ + PEVLQDSL
Sbjct: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
Query: 609 DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647
DRCYST S EL DS Q YRS FY E++ + A+ +D
Sbjct: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579
Score = 696 bits (1795), Expect = 0.0
Identities = 386/602 (64%), Positives = 439/602 (72%), Gaps = 36/602 (5%)
Query: 90 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
+E+ +Y+ + Q+ +L +L + ++ + + TP +P S
Sbjct: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
Query: 141 GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197
L+EQ G L ++K D +++ED Q PR E+ + E
Sbjct: 395 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 439
Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
EV +DSL+ C T S+ DS QP+ + EE V +L + +
Sbjct: 440 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 499
Query: 258 ENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIPPEMLASYQS 309
++ + E EE++ P PR +E +E EV Q+S D YST S E+ S Q
Sbjct: 500 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 559
Query: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369
Y S F+ LE+Q+V +AVD+ Q +EDQ+ + PRLS ELLDEKEPEVLQ+SLDRCY
Sbjct: 560 YRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCY 619
Query: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429
STPSGCLELTDSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 620 STPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 679
Query: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 489
EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 680 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 739
Query: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549
DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 740 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 799
Query: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSL 608
SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRLN +LMEVEEPEVLQDSL
Sbjct: 800 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSL 859
Query: 609 DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 668
D CYST SMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF
Sbjct: 860 DICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 919
Query: 669 PQ 670
PQ
Sbjct: 920 PQ 921
>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
Length = 790
Score = 998 bits (2580), Expect = 0.0
Identities = 506/582 (86%), Positives = 528/582 (90%), Gaps = 1/582 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 437 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 496
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PE LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 497 PERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 556
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPS L LTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 557 LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 616
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELL EKEPEVLQDSLDRCYSTPS YLELPDLGQPY SAVYSLEEQYLGLALDVDR
Sbjct: 617 PRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDR 676
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD P L P F
Sbjct: 677 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFM 735
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGE 582
+ + F L +++++G+G+K ++K K+G+
Sbjct: 736 HWRKNMLAFLLTWEKLKRRGRGRKEGEEDQRRKEEGEEKKGK 777
Score = 382 bits (981), Expect = e-106
Identities = 260/620 (41%), Positives = 337/620 (54%), Gaps = 96/620 (15%)
Query: 90 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
+E++QYKVLVH+QERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15 QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74
Query: 150 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 209
EGCRL QHLVQKLSPEND D+DEDVQVE EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75 EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134
Query: 210 TCSNSHGPYDSNQPHKKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 267
TCSNSHGP DS QPHK KITFEEDKV+S+L+ SSH +DA++I+P
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILP---------- 184
Query: 268 EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 322
GP S P S + L I ++ F SL+E Q
Sbjct: 185 VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244
Query: 323 C-MAVDIGRHRWDQVK-------KEDQEATGPRLSRELLDEKE----------------- 357
C +A ++++++ K + +++ +L+ +L +E
Sbjct: 245 CFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 304
Query: 358 -PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV-GLAI-------------- 401
E L++ D S L +P +S L++Q G +
Sbjct: 305 LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 364
Query: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
D DE + + E+ Q S P RE+ +E EV +DSL+ C T S+ D QP+
Sbjct: 365 DDDEDVQVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 421
Query: 462 SAVYSLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 507
+ EE + L + + D EEEE++GP P R L E E
Sbjct: 422 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---RNLQESEE 478
Query: 508 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 567
EV Q+S D YST S E+ S Q Y S+F++LEE+ V ++D+G
Sbjct: 479 EEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------------- 525
Query: 568 RRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQH 627
+ R + + ED PRL+ L++ +EPEVLQDSLDRCYST S+Y L DS Q
Sbjct: 526 -----RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQP 580
Query: 628 YRSVFYSFEEEHISFALYVD 647
YRS FY E++ I A+ +D
Sbjct: 581 YRSAFYVLEQQRIGLAVDMD 600
Score = 224 bits (572), Expect = 2e-58
Identities = 142/327 (43%), Positives = 187/327 (57%), Gaps = 38/327 (11%)
Query: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
+V ++ Q+++ PR E+ +E EV +DSL+ C T S DS QP+R E+
Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429
Query: 395 QRVGLAID--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 440
+V + + E E E EE++ P PR L + +E EV Q+S
Sbjct: 430 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESW 486
Query: 441 DRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSR 500
D YST S E Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSR
Sbjct: 487 DEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 546
Query: 501 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 560
ELL+ EPEVLQDSLDRCYSTPS L DSCQPY S+FY LE++ +G ++D+ EIEK
Sbjct: 547 ELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY- 605
Query: 561 KGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFE 620
++ ED +P CPRL+ L+ +EPEVLQDSLDRCYST S Y E
Sbjct: 606 -----------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLE 648
Query: 621 LPDSFQHYRSVFYSFEEEHISFALYVD 647
LPD Q YRS YS EE+++ AL VD
Sbjct: 649 LPDLGQPYRSAVYSLEEQYLGLALDVD 675
Score = 38.1 bits (87), Expect = 0.027
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 21/186 (11%)
Query: 295 STLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD 354
ST +P + Q Y HS E + + + R + E L+ + D
Sbjct: 5 STGRLPGQPTQEIQQYKVLVHSQERELTQLREKLREGR--DASRSLNEHLQALLTPDEPD 62
Query: 355 EKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEE 414
+ + + LQ+ L GC R A +++ Q++ D DE E Q VEE
Sbjct: 63 KSQGQDLQEQL------AEGC----------RLAQHLV--QKLSPENDEDEDEDVQ-VEE 103
Query: 415 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGL 474
D+ RE+ +E +V +DSL+ C T S+ D QP+ + + EE +
Sbjct: 104 DEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNS 163
Query: 475 ALDVDR 480
+L VDR
Sbjct: 164 SLVVDR 169
>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
sapiens]
Length = 790
Score = 998 bits (2580), Expect = 0.0
Identities = 506/582 (86%), Positives = 528/582 (90%), Gaps = 1/582 (0%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 437 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 496
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
PE LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 497 PERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 556
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDRCYSTPS L LTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 557 LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 616
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSRELL EKEPEVLQDSLDRCYSTPS YLELPDLGQPY SAVYSLEEQYLGLALDVDR
Sbjct: 617 PRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDR 676
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD P L P F
Sbjct: 677 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFM 735
Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGE 582
+ + F L +++++G+G+K ++K K+G+
Sbjct: 736 HWRKNMLAFLLTWEKLKRRGRGRKEGEEDQRRKEEGEEKKGK 777
Score = 383 bits (984), Expect = e-106
Identities = 261/620 (42%), Positives = 337/620 (54%), Gaps = 96/620 (15%)
Query: 90 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
EE++QYKVLVH+QERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15 EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74
Query: 150 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 209
EGCRL QHLVQKLSPEND D+DEDVQVE EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75 EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134
Query: 210 TCSNSHGPYDSNQPHKKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 267
TCSNSHGP DS QPHK KITFEEDKV+S+L+ SSH +DA++I+P
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILP---------- 184
Query: 268 EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 322
GP S P S + L I ++ F SL+E Q
Sbjct: 185 VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244
Query: 323 C-MAVDIGRHRWDQVK-------KEDQEATGPRLSRELLDEKE----------------- 357
C +A ++++++ K + +++ +L+ +L +E
Sbjct: 245 CFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 304
Query: 358 -PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV-GLAI-------------- 401
E L++ D S L +P +S L++Q G +
Sbjct: 305 LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 364
Query: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
D DE + + E+ Q S P RE+ +E EV +DSL+ C T S+ D QP+
Sbjct: 365 DDDEDVQVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 421
Query: 462 SAVYSLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 507
+ EE + L + + D EEEE++GP P R L E E
Sbjct: 422 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---RNLQESEE 478
Query: 508 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 567
EV Q+S D YST S E+ S Q Y S+F++LEE+ V ++D+G
Sbjct: 479 EEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------------- 525
Query: 568 RRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQH 627
+ R + + ED PRL+ L++ +EPEVLQDSLDRCYST S+Y L DS Q
Sbjct: 526 -----RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQP 580
Query: 628 YRSVFYSFEEEHISFALYVD 647
YRS FY E++ I A+ +D
Sbjct: 581 YRSAFYVLEQQRIGLAVDMD 600
Score = 224 bits (572), Expect = 2e-58
Identities = 142/327 (43%), Positives = 187/327 (57%), Gaps = 38/327 (11%)
Query: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
+V ++ Q+++ PR E+ +E EV +DSL+ C T S DS QP+R E+
Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429
Query: 395 QRVGLAID--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 440
+V + + E E E EE++ P PR L + +E EV Q+S
Sbjct: 430 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESW 486
Query: 441 DRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSR 500
D YST S E Q YSS +SLEEQ + +A+D+ R + DQ ++EDQ PRLSR
Sbjct: 487 DEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 546
Query: 501 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 560
ELL+ EPEVLQDSLDRCYSTPS L DSCQPY S+FY LE++ +G ++D+ EIEK
Sbjct: 547 ELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY- 605
Query: 561 KGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFE 620
++ ED +P CPRL+ L+ +EPEVLQDSLDRCYST S Y E
Sbjct: 606 -----------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLE 648
Query: 621 LPDSFQHYRSVFYSFEEEHISFALYVD 647
LPD Q YRS YS EE+++ AL VD
Sbjct: 649 LPDLGQPYRSAVYSLEEQYLGLALDVD 675
Score = 38.1 bits (87), Expect = 0.027
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 21/186 (11%)
Query: 295 STLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD 354
ST +P + Q Y HS E + + + R + E L+ + D
Sbjct: 5 STGRLPGQPTEEIQQYKVLVHSQERELTQLREKLREGR--DASRSLNEHLQALLTPDEPD 62
Query: 355 EKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEE 414
+ + + LQ+ L GC R A +++ Q++ D DE E Q VEE
Sbjct: 63 KSQGQDLQEQL------AEGC----------RLAQHLV--QKLSPENDEDEDEDVQ-VEE 103
Query: 415 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGL 474
D+ RE+ +E +V +DSL+ C T S+ D QP+ + + EE +
Sbjct: 104 DEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNS 163
Query: 475 ALDVDR 480
+L VDR
Sbjct: 164 SLVVDR 169
>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
sapiens]
Length = 633
Score = 818 bits (2114), Expect = 0.0
Identities = 419/553 (75%), Positives = 466/553 (84%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGP S EKAEMNILEIN+K RPQLAE KQQFRNLK+KC +TQ+A FLANRQ Y Y
Sbjct: 57 MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
E+CKDLIK MLR+ER EEKLAE+L QAEELRQYKVLVH+QERELTQLREKL+EGRDAS
Sbjct: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRL QHLVQKLSPEND+D+DEDV+VE AE
Sbjct: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQ+ APRE+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+ T+ITFEED+VDSTL
Sbjct: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
I SSSH EW DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQESWDEG TLSIP
Sbjct: 297 IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIP 356
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
P+M ASYQS STFHS+EEQQV +A+DIGRH DQVKKEDQEAT PRLSRELLDEKEPEV
Sbjct: 357 PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEV 416
Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
LQDSLDR YSTP LEL D CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P C
Sbjct: 417 LQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPC 476
Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480
PRLSREL + EPE LQDSLDR YSTP Y ELPD QPY S YSLEE+++G +LDVD
Sbjct: 477 PRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDE 536
Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
I+K QE EEDQ PPCPRL+ L+E EPEVLQDSLDRCYST S+ + S Q Y S+FY
Sbjct: 537 IEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFY 596
Query: 541 ALEEKHVGFSLDV 553
+ EE+ V +LDV
Sbjct: 597 SFEEQDVSLALDV 609
>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
[Homo sapiens]
Length = 299
Score = 530 bits (1366), Expect = e-150
Identities = 267/287 (93%), Positives = 275/287 (95%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQLAGFLA +Q KYKY
Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61 EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 287
IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR S E+ P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 17/112 (15%)
Query: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
D DE + + E+ Q S PR E+ +E EV +DSL+ C T S+ D QP+
Sbjct: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
Query: 462 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLS 499
+ EE + L + + D EEEE++GP PR S
Sbjct: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
Score = 37.7 bits (86), Expect = 0.035
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 17/104 (16%)
Query: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
+V ++ Q+++ PR E+ +E EV +DSL+ C T S DS QP+R E+
Sbjct: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
Query: 395 QRVGLAI--------------DMDEIEKYQEVEEDQDPSCPRLS 424
+V + + E E E EE++ P PR S
Sbjct: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
Score = 32.7 bits (73), Expect = 1.1
Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 27/163 (16%)
Query: 404 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463
+E+ +Y+ + Q+ +L +L + ++ R + L PD +P S
Sbjct: 90 EELRQYKVLVHSQERELTQLREKLREGRDAS-------RSLNEHLQALLTPD--EPDKSQ 140
Query: 464 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 508
L+EQ G L ++K D +++ED Q PR E+ + E
Sbjct: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
Query: 509 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 551
EV +DSL+ C T S+ DS QP+ + EE V +L
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
Score = 31.6 bits (70), Expect = 2.5
Identities = 18/50 (36%), Positives = 26/50 (52%)
Query: 595 LMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFAL 644
+ + EE EV +DSL+ C T S DS Q +R +FEE+ + L
Sbjct: 191 MQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
[Homo sapiens]
Length = 667
Score = 483 bits (1242), Expect = e-136
Identities = 282/504 (55%), Positives = 350/504 (69%), Gaps = 28/504 (5%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + LAN+ KKYK
Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119
Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177
SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179
Query: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237
EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239
Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES---WDE 292
S L+ S H E E+A++I PEN++D EEEE K PV PRN Q E E+
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNLRDFLISP 299
Query: 293 GYSTLSIP--PEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED 340
S ++ P + SY+ +F +L+EQ+VC A D+ R +WD+ K+ D
Sbjct: 300 VVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSD 359
Query: 341 ------QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
QE PRLSR L + E+ Q+SLD C TPS +LT S PY S Y E
Sbjct: 360 LEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 419
Query: 395 QRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELP 454
++V LA+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++
Sbjct: 420 KQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVS 478
Query: 455 DLGQPYSSAVYSLEEQYLGLALDV 478
D QPYSS + SLE+Q ALDV
Sbjct: 479 DCHQPYSSTLSSLEDQLACSALDV 502
Score = 113 bits (282), Expect = 6e-25
Identities = 106/351 (30%), Positives = 155/351 (44%), Gaps = 64/351 (18%)
Query: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393
D+ ++ QE+ PR E+ +E EV QDSL+ C T S ++S QP+RS +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234
Query: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
+ V A+ ++ E + E EE + P PR + L EP L
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSL----EPGELT 290
Query: 438 DSLDRCYSTPSDYLELP---DLGQPYSSAVYS---LEEQYLGLALDVDRI---------- 481
+ D S ++ P D Y S L+EQ + A DV R
Sbjct: 291 NLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETS 350
Query: 482 ------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535
+ D EE + Q PRLSR L V + E+ Q+SLD C TPS + S PY
Sbjct: 351 LGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPY 410
Query: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVL 595
S+ Y+ E+K V +L K ++ ++E ED +PPCPRL+ L
Sbjct: 411 WSTLYSFEDKQVSLAL-------------------VDKIKKDQEEIEDQSPPCPRLSQEL 451
Query: 596 MEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646
EV+E EV +DS++ Y T S++ ++ D Q Y S S E++ AL V
Sbjct: 452 PEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502
Score = 36.6 bits (83), Expect = 0.077
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646
P PR + + EE EV QDSL+ C T S +S Q +RS +F+E + AL V
Sbjct: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244
Query: 647 DN 648
++
Sbjct: 245 ES 246
>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
[Homo sapiens]
Length = 638
Score = 479 bits (1232), Expect = e-135
Identities = 277/499 (55%), Positives = 343/499 (68%), Gaps = 47/499 (9%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + LAN+ KKYK
Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119
Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177
SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179
Query: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237
EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239
Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 295
S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285
Query: 296 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 340
SY+ +F +L+EQ+VC A D+ R +WD+ K+ D
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335
Query: 341 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 399
QE PRLSR L + E+ Q+SLD C TPS +LT S PY S Y E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395
Query: 400 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQP 459
A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454
Query: 460 YSSAVYSLEEQYLGLALDV 478
YSS + SLE+Q ALDV
Sbjct: 455 YSSTLSSLEDQLACSALDV 473
Score = 114 bits (285), Expect = 3e-25
Identities = 99/329 (30%), Positives = 150/329 (45%), Gaps = 49/329 (14%)
Query: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393
D+ ++ QE+ PR E+ +E EV QDSL+ C T S ++S QP+RS +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234
Query: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
+ V A+ ++ E + E EE + P PR + + EV
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSF 294
Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPR 497
+LD D+ + YS+ + +E LG + D EE + Q PR
Sbjct: 295 LALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPR 343
Query: 498 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557
LSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L
Sbjct: 344 LSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL------ 397
Query: 558 KKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSM 617
K ++ ++E ED +PPCPRL+ L EV+E EV +DS++ Y T S+
Sbjct: 398 -------------VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444
Query: 618 YFELPDSFQHYRSVFYSFEEEHISFALYV 646
+ ++ D Q Y S S E++ AL V
Sbjct: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473
Score = 36.6 bits (83), Expect = 0.077
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646
P PR + + EE EV QDSL+ C T S +S Q +RS +F+E + AL V
Sbjct: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244
Query: 647 DN 648
++
Sbjct: 245 ES 246
>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
sapiens]
Length = 638
Score = 479 bits (1232), Expect = e-135
Identities = 277/499 (55%), Positives = 343/499 (68%), Gaps = 47/499 (9%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + LAN+ KKYK
Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119
Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177
SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179
Query: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237
EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239
Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 295
S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285
Query: 296 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 340
SY+ +F +L+EQ+VC A D+ R +WD+ K+ D
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335
Query: 341 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 399
QE PRLSR L + E+ Q+SLD C TPS +LT S PY S Y E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395
Query: 400 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQP 459
A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454
Query: 460 YSSAVYSLEEQYLGLALDV 478
YSS + SLE+Q ALDV
Sbjct: 455 YSSTLSSLEDQLACSALDV 473
Score = 114 bits (285), Expect = 3e-25
Identities = 99/329 (30%), Positives = 150/329 (45%), Gaps = 49/329 (14%)
Query: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393
D+ ++ QE+ PR E+ +E EV QDSL+ C T S ++S QP+RS +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234
Query: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
+ V A+ ++ E + E EE + P PR + + EV
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSF 294
Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPR 497
+LD D+ + YS+ + +E LG + D EE + Q PR
Sbjct: 295 LALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPR 343
Query: 498 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557
LSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L
Sbjct: 344 LSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL------ 397
Query: 558 KKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSM 617
K ++ ++E ED +PPCPRL+ L EV+E EV +DS++ Y T S+
Sbjct: 398 -------------VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444
Query: 618 YFELPDSFQHYRSVFYSFEEEHISFALYV 646
+ ++ D Q Y S S E++ AL V
Sbjct: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473
Score = 36.6 bits (83), Expect = 0.077
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646
P PR + + EE EV QDSL+ C T S +S Q +RS +F+E + AL V
Sbjct: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244
Query: 647 DN 648
++
Sbjct: 245 ES 246
>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
Length = 421
Score = 451 bits (1159), Expect = e-126
Identities = 244/372 (65%), Positives = 281/372 (75%), Gaps = 11/372 (2%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K +TQ+AGFLAN+Q KYKY
Sbjct: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
Query: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS
Sbjct: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
SLN+HLQALLTPD+ D SQGQD +EQLAEGCRL +HLV KLSPEND D+DE+ + + +
Sbjct: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PHK KIT EEDKV+S L
Sbjct: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESW 290
+ SS EW+DA++I+ EN++DDEEEE K PV P+ LQESEE+EV Q+S
Sbjct: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320
Query: 291 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 350
+E +T ++ SYQ TF +L EQ+VC A D+ K E+ P
Sbjct: 321 EERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSKGEETPLGFPDTKY 379
Query: 351 ELLDEKEPEVLQ 362
DEK+ + Q
Sbjct: 380 CWKDEKDERMSQ 391
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)
Query: 377 ELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 436
+L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
Query: 437 QDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 480
+DSL+ C T S+ D P+ + + EE + L VD
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
Query: 481 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535
+ D EEEE + P P+++ +L E E EVLQDS + +T S + S QP
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
Query: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 564
+F AL E+ V + DV KG++
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/170 (27%), Positives = 71/170 (41%), Gaps = 6/170 (3%)
Query: 477 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536
D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+
Sbjct: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
Query: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRL---NG 593
+ EE V L V + + + + + +EG+ PP L
Sbjct: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305
Query: 594 VLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFA 643
L E EE EVLQDS + +T ++ S+Q F + E+ + A
Sbjct: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646
P PR + EE EV +DSL+ C T S DS ++++ + EE+ ++ L V
Sbjct: 206 PAPREE---QKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVV 262
Query: 647 DN 648
D+
Sbjct: 263 DS 264
>gi|239758011 PREDICTED: hypothetical protein LOC728841, partial
[Homo sapiens]
Length = 166
Score = 224 bits (572), Expect = 2e-58
Identities = 111/144 (77%), Positives = 123/144 (85%), Gaps = 1/144 (0%)
Query: 526 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD- 584
LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGE+D
Sbjct: 1 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60
Query: 585 NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFAL 644
NPPCPRL+ L++ +EPEVLQDSLDRCYST S Y ELPD Q Y S YS EE+++ AL
Sbjct: 61 NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120
Query: 645 YVDNRFFTLTVTSLHLVFQMGVIF 668
VD+ + T+ V SLHLVFQ+GVIF
Sbjct: 121 DVDSEYLTMKVISLHLVFQIGVIF 144
Score = 164 bits (415), Expect = 2e-40
Identities = 85/123 (69%), Positives = 93/123 (75%), Gaps = 19/123 (15%)
Query: 376 LELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY-------------------QEVEEDQ 416
LE DSCQPY S+FY LE++ VG ++D+ EIEK +E EEDQ
Sbjct: 1 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60
Query: 417 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL 476
+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61 NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120
Query: 477 DVD 479
DVD
Sbjct: 121 DVD 123
Score = 128 bits (321), Expect = 2e-29
Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)
Query: 451 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 491
LE PD QPY S+ Y+LEE+++G +LDV I+K +E EEDQ
Sbjct: 1 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60
Query: 492 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 551
PPCPRLSRELL+ EPEVLQDSLDRCYSTPS LE PD QPY S+ Y+LEE+++G +L
Sbjct: 61 NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120
Query: 552 DV 553
DV
Sbjct: 121 DV 122
Score = 112 bits (281), Expect = 8e-25
Identities = 63/118 (53%), Positives = 76/118 (64%), Gaps = 19/118 (16%)
Query: 306 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
S Q Y S+F++LEE+ V ++D+G R R + +EDQ P
Sbjct: 6 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65
Query: 347 RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMD 404
RLSRELLDEKEPEVLQDSLDRCYSTPSG LEL D QPY SA Y LE+Q +GLA+D+D
Sbjct: 66 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 123
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/68 (42%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Query: 264 EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 320
E EE++ P PR L + +E EV Q+S D YST S E+ Q YSS +SLEEQ
Sbjct: 55 EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 114
Query: 321 QVCMAVDI 328
+ +A+D+
Sbjct: 115 YLGLALDV 122
>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
member 6-like protein [Homo sapiens]
Length = 298
Score = 119 bits (298), Expect = 9e-27
Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 9/190 (4%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
M VSA +AEM+ILE N+ LR +L + KQ F++L EK ++ + L N +KYK
Sbjct: 1 MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EECKDLI+ +L E QF+E +LAE + A LR + L+ AQ ELT LR+K++EGR
Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120
Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
+H+ + LL + Q Q EQ+ +G +LT+ LV+KL+ EN N +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180
Query: 172 EDVQVEVAEK 181
ED Q +A +
Sbjct: 181 EDRQKPLAPR 190
>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
member 6-like protein [Homo sapiens]
Length = 298
Score = 116 bits (291), Expect = 6e-26
Identities = 75/190 (39%), Positives = 109/190 (57%), Gaps = 9/190 (4%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
M VSA +AE++ILE N+ LR +L + KQ F++L EK ++ + L N +KYK
Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EECKDLI+ +L E QF+E +LAE + A LR + L+ AQ ELT LR+K +EGR
Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120
Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
+H+ + LL + Q Q EQ+ +G +LT+ LV+KL+ EN N +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180
Query: 172 EDVQVEVAEK 181
ED Q +A +
Sbjct: 181 EDRQKPLAPR 190
>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
6-like protein [Homo sapiens]
Length = 322
Score = 116 bits (291), Expect = 6e-26
Identities = 75/190 (39%), Positives = 109/190 (57%), Gaps = 9/190 (4%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
M VSA +AE++ILE N+ LR +L + KQ F++L EK ++ + L N +KYK
Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EECKDLI+ +L E QF+E +LAE + A LR + L+ AQ ELT LR+K +EGR
Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120
Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
+H+ + LL + Q Q EQ+ +G +LT+ LV+KL+ EN N +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180
Query: 172 EDVQVEVAEK 181
ED Q +A +
Sbjct: 181 EDRQKPLAPR 190
>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
6-like protein [Homo sapiens]
Length = 298
Score = 114 bits (284), Expect = 4e-25
Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)
Query: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
M VSA +AE++ILE N+ LR +L + KQ F++L EK ++ + L N +KYK
Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60
Query: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
EECKDLI+ +L E QF+E +LAE + A LR + L+ AQ ELT LR+K +EGR
Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120
Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
+H+ + LL Q Q EQ+ +G +LT+ LV+KL EN N +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180
Query: 172 EDVQVEVAEK 181
ED Q +A +
Sbjct: 181 EDRQKPLAPR 190
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
sapiens]
Length = 2346
Score = 80.5 bits (197), Expect = 5e-15
Identities = 58/182 (31%), Positives = 97/182 (53%), Gaps = 14/182 (7%)
Query: 79 EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEH-------LQALL 131
EEKLAE+L+ A +Y L+ Q REL+ LR+K+REGR + H + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517
Query: 132 TPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVE-VAEKVQKSSAPRE 190
++ D GQ +EQLA+G +LT+ L KLS ++ + + +E +A ++ RE
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLS-----RE 1572
Query: 191 MQKAEEK-EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEW 249
+Q+ E+ EV + L+ ++T S+SH DS++ T +E + S + S + +
Sbjct: 1573 LQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHY 1632
Query: 250 ED 251
E+
Sbjct: 1633 EE 1634
Score = 38.1 bits (87), Expect = 0.027
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 6/85 (7%)
Query: 334 DQVKKEDQEATGP---RLSRELLD-EKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 389
D ++DQ P RLSREL + EK EVLQ LD TPS L+DS + S
Sbjct: 1552 DHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTS 1611
Query: 390 YVLEQQRVGLAIDMDEIEKYQEVEE 414
++ ++ + DMD + +Y EE
Sbjct: 1612 FLSDE--LEACSDMDIVSEYTHYEE 1634
Score = 35.4 bits (80), Expect = 0.17
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 408 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463
K + E+DQ +P RLSREL + EK EVLQ LD TPS L D + SS
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610
Query: 464 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 494
+ +E L D+D + + EE + P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639
Score = 34.3 bits (77), Expect = 0.38
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 483 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538
KD + E+DQ P RLSREL E + EVLQ LD TPSS DS + S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610
Query: 539 FYALEEKHVGFSLDV 553
+ +E +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625
Score = 32.7 bits (73), Expect = 1.1
Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 34/187 (18%)
Query: 14 EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN 73
E NI +N L + K+Q + +E L R K E +++ LR
Sbjct: 433 EQNIQHLNHSL----SHKEQLLQEFRE---------LLQYRDNSDKTLEANEMLLEKLRQ 479
Query: 74 ERQFK--------EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 125
K +EK + ++ +ELRQ ++ V ++ +L +LR+ L +S+
Sbjct: 480 RIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMES 539
Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
L+A +G ++ EQL+ C+ Q L +++ + E Q + +++Q S
Sbjct: 540 LLRA----------KGLEV-EQLSTTCQNLQWLKEEMETKFSRWQKE--QESIIQQLQTS 586
Query: 186 SAPREMQ 192
R +
Sbjct: 587 LHDRNKE 593
Score = 30.8 bits (68), Expect = 4.2
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 90 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
E+ R+ + + RE +Q E LRE +SRS HLQ L E K + Q L E L
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLREALLSSRS---HLQELEKELEHQKVERQQLLEDLR 1965
Query: 150 EGCRLTQHLVQKLSPENDND 169
E + H ++ +ND
Sbjct: 1966 EKQQEVLHFREERLSLQEND 1985
Score = 30.4 bits (67), Expect = 5.5
Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 13/134 (9%)
Query: 18 LEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM------L 71
LEI +KL+ + +K++Q + K+ + A + +QK+ ++ ++L K + L
Sbjct: 353 LEI-QKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEEL 411
Query: 72 RNE----RQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKL--REGRDASRSLNE 125
+N+ R ++ EK E Q + ++ + +E+ L + RE L R+ D + NE
Sbjct: 412 QNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANE 471
Query: 126 HLQALLTPDEPDKS 139
L L DK+
Sbjct: 472 MLLEKLRQRIHDKA 485
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 65.9 bits (159), Expect = 1e-10
Identities = 111/582 (19%), Positives = 221/582 (37%), Gaps = 68/582 (11%)
Query: 8 LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
+++E+ + E+ EKLR +EK + N+KE K K E K L+
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL---------------KRKLERAKFLL 224
Query: 68 KFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL 127
+ N Q E +Q EELR+ + + QE ++ + E+LRE R E +
Sbjct: 225 PQVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKM 278
Query: 128 QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSA 187
+ + + ++ +++L E +L + Q E + E+ E EK+ +
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 188 ---PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSS 244
+E Q E+++ D E D K+ ++ E++K+
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERM--------WEQDERLREKEERMR-EQEKMWEQEEKMQ 389
Query: 245 SHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEML 304
+ + E E E+EEK N+ E EE+E Q+ E L +M
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 305 ASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDS 364
+ + +Q+ + + W Q K +QE ++ D+++ + D
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQEDQMWEQEEKMRDQEQK--MWDQ 505
Query: 365 LDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAID------MDEIEKYQEVEEDQDP 418
+R + E + + + + E+ R D+ EK +E E ++
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER 565
Query: 419 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDV 478
E + ++ E +Q+ ++ E + Q ++ EE
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE--------- 616
Query: 479 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538
K ++EEED+ +E + + E +Q+ ++ + EQ + +
Sbjct: 617 ---KMWEQEEEDK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ--- 665
Query: 539 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKE 580
EEK G + E E+K +G++ + R ++++ RG++E
Sbjct: 666 ----EEKMQGQEEKMREQEEKMQGQEEK-MREQEEKMRGQEE 702
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 62.0 bits (149), Expect = 2e-09
Identities = 63/279 (22%), Positives = 121/279 (43%), Gaps = 32/279 (11%)
Query: 32 KQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLA-EQLKQAE 90
++Q R KE+ + A L + Y K +IKF E Q ++++LA +Q+++A+
Sbjct: 366 EEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425
Query: 91 ELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAE 150
+LR+++ +H Q + LR++ ++ + +R + QA L E + Q Q+ Q A
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAEL---EEGRPQHQEQLRQQAH 482
Query: 151 GCRLTQHLVQKLSP----------ENDNDDDEDVQVEVAEKVQ-KSSAPREMQKAEEKE- 198
+ +VQ E DN ++ + + + + + PRE E +
Sbjct: 483 YDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADR 542
Query: 199 --------------VPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSS 244
ED EE A + P D N+ K++ E +V+ L+ +
Sbjct: 543 AAVEDINPADDPNNQGEDEFEE-AEQVREENLP-DENEEQKQSNQKQENTEVEEHLVMAG 600
Query: 245 SHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE 283
+ + ED V + E+++E +E+ R L+ + EE
Sbjct: 601 NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/147 (23%), Positives = 60/147 (40%), Gaps = 26/147 (17%)
Query: 136 PDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDD-DEDVQVEVAEKVQKSSAPREMQKA 194
PD+++ Q Q E + +HLV +P+ D+ DE Q E E+VQ
Sbjct: 574 PDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQ----------- 622
Query: 195 EEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVH 254
+++ E+ E ++G D N K +E + D+ G H
Sbjct: 623 --EDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHY------- 673
Query: 255 IIPENESDDEEEEEKGPVSPRNLQESE 281
E ++EEEE+ V+ ++ + +E
Sbjct: 674 -----EEEEEEEEDGAAVAEKSHRRAE 695
Score = 37.7 bits (86), Expect = 0.035
Identities = 95/497 (19%), Positives = 192/497 (38%), Gaps = 77/497 (15%)
Query: 17 ILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAG---FLANRQKKYKYEECKDLIKFMLRN 73
+ E +L L +++ + + KE + +L RQ ++ ML++
Sbjct: 64 VYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKS 123
Query: 74 ERQFKEEKLA----EQLKQAEEL--------RQYKVLVHAQERELTQLREKLREGRDASR 121
+ + +++ + E KQ E+ ++Y L +E+EL++L+E + R+ +R
Sbjct: 124 QHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENR 183
Query: 122 SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEK 181
L + Q + T + K Q ++L L++H ++ E+ Q +VAE
Sbjct: 184 QLRKAHQDIHTQLQDVKQQHKNL---------LSEHEQLVVTLEDHKSALAAAQTQVAEY 234
Query: 182 VQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLI 241
Q + + D E+ +T +H P N +K T E +V
Sbjct: 235 KQLKDTLNRIPSLRK----PDPAEQQNVT-QVAHSPQGYNTAREKP--TREVQEV----- 282
Query: 242 GSSSHVEWEDAVHIIPENESDDE-----EEEEKGPVSPRNLQESEEEEVPQESWDEGYST 296
S ++ W++ +P D + +E + P +Q+ E P+E E
Sbjct: 283 -SRNNDVWQNH-EAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVE---- 336
Query: 297 LSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK 356
+ + E +QV A + +++D+E +E +++
Sbjct: 337 -----------EEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDRE------WKEQHEQR 379
Query: 357 EPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQ 416
E L + R PS + PY LEQQR+ + ++E+ Q++ E Q
Sbjct: 380 EAANLLEGHARAEVYPS-AKPMIKFQSPYEEQ---LEQQRLA----VQQVEEAQQLREHQ 431
Query: 417 DP-SCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLA 475
+ RL LL ++E + Q + + ++ E G+P + Y +
Sbjct: 432 EALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEE----GRPQHQEQLRQQAHYDAMD 487
Query: 476 LDVDRIKKDQEEEEDQG 492
D+ + +DQ + ++G
Sbjct: 488 NDIVQGAEDQGIQGEEG 504
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.5 bits (140), Expect = 2e-08
Identities = 96/474 (20%), Positives = 196/474 (41%), Gaps = 54/474 (11%)
Query: 25 RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
R A+++QQ +K A +L + + +++ +K +L+ RQ +E + E
Sbjct: 803 RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
Query: 85 QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
Q + RQ K E EL +L +K + + L E LQA + ++ +++
Sbjct: 859 DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 909
Query: 145 QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
+ +LA + + ++ ++ + ++D Q++ K ++ EE+E L
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 205 EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
+ +T + KI ED++ L+ + + ++ E SD
Sbjct: 970 QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1012
Query: 263 ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
+EEE+ K +N ES E+ E S + ++ + +S FH
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1068
Query: 319 EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
EQ + I + KKE++ +A RL E+ + ++L + +
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1122
Query: 378 LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
L + R+A E+Q+ L +++ ++ E+E+ D + + E+E VL+
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1180
Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLE---EQYLGLALDVDRIKKDQEEE 488
+LD T S ++ ++ Q ++ AV L EQ+ ++D+ K+ E+E
Sbjct: 1181 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Score = 33.9 bits (76), Expect = 0.50
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 10 SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
+E A + N++LR +L E + ++ K K + L +A +++ + E + K
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1838
Query: 70 MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
+ K++KL E L Q E+ R QYK + QL+ +L E + S+ +N
Sbjct: 1839 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1898
Query: 126 HLQAL 130
+ + L
Sbjct: 1899 NRRKL 1903
Score = 30.4 bits (67), Expect = 5.5
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 14 EMNILEINEKLRPQLAEK-------KQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDL 66
E I ++ E++ + EK KQ+ + LKE + +A + K+ + E+
Sbjct: 1820 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE-QAEKGNAR 1878
Query: 67 IKFMLRNERQFKEEKL---AEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
+K + R + +EE A + K EL + A RE+ L+ KLR G + S
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.5 bits (140), Expect = 2e-08
Identities = 96/474 (20%), Positives = 196/474 (41%), Gaps = 54/474 (11%)
Query: 25 RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
R A+++QQ +K A +L + + +++ +K +L+ RQ +E + E
Sbjct: 810 RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865
Query: 85 QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
Q + RQ K E EL +L +K + + L E LQA + ++ +++
Sbjct: 866 DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 916
Query: 145 QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
+ +LA + + ++ ++ + ++D Q++ K ++ EE+E L
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 205 EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
+ +T + KI ED++ L+ + + ++ E SD
Sbjct: 977 QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1019
Query: 263 ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
+EEE+ K +N ES E+ E S + ++ + +S FH
Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1075
Query: 319 EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
EQ + I + KKE++ +A RL E+ + ++L + +
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1129
Query: 378 LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
L + R+A E+Q+ L +++ ++ E+E+ D + + E+E VL+
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1187
Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLE---EQYLGLALDVDRIKKDQEEE 488
+LD T S ++ ++ Q ++ AV L EQ+ ++D+ K+ E+E
Sbjct: 1188 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Score = 33.9 bits (76), Expect = 0.50
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 10 SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
+E A + N++LR +L E + ++ K K + L +A +++ + E + K
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1845
Query: 70 MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
+ K++KL E L Q E+ R QYK + QL+ +L E + S+ +N
Sbjct: 1846 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1905
Query: 126 HLQAL 130
+ + L
Sbjct: 1906 NRRKL 1910
Score = 30.4 bits (67), Expect = 5.5
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 14 EMNILEINEKLRPQLAEK-------KQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDL 66
E I ++ E++ + EK KQ+ + LKE + +A + K+ + E+
Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE-QAEKGNAR 1885
Query: 67 IKFMLRNERQFKEEKL---AEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
+K + R + +EE A + K EL + A RE+ L+ KLR G + S
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1942
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.5 bits (140), Expect = 2e-08
Identities = 96/474 (20%), Positives = 196/474 (41%), Gaps = 54/474 (11%)
Query: 25 RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
R A+++QQ +K A +L + + +++ +K +L+ RQ +E + E
Sbjct: 810 RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865
Query: 85 QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
Q + RQ K E EL +L +K + + L E LQA + ++ +++
Sbjct: 866 DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 916
Query: 145 QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
+ +LA + + ++ ++ + ++D Q++ K ++ EE+E L
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 205 EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
+ +T + KI ED++ L+ + + ++ E SD
Sbjct: 977 QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1019
Query: 263 ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
+EEE+ K +N ES E+ E S + ++ + +S FH
Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1075
Query: 319 EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
EQ + I + KKE++ +A RL E+ + ++L + +
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1129
Query: 378 LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
L + R+A E+Q+ L +++ ++ E+E+ D + + E+E VL+
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1187
Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLE---EQYLGLALDVDRIKKDQEEE 488
+LD T S ++ ++ Q ++ AV L EQ+ ++D+ K+ E+E
Sbjct: 1188 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Score = 33.9 bits (76), Expect = 0.50
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 10 SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
+E A + N++LR +L E + ++ K K + L +A +++ + E + K
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1845
Query: 70 MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
+ K++KL E L Q E+ R QYK + QL+ +L E + S+ +N
Sbjct: 1846 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1905
Query: 126 HLQAL 130
+ + L
Sbjct: 1906 NRRKL 1910
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 58.5 bits (140), Expect = 2e-08
Identities = 96/474 (20%), Positives = 196/474 (41%), Gaps = 54/474 (11%)
Query: 25 RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
R A+++QQ +K A +L + + +++ +K +L+ RQ +E + E
Sbjct: 803 RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
Query: 85 QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
Q + RQ K E EL +L +K + + L E LQA + ++ +++
Sbjct: 859 DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 909
Query: 145 QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
+ +LA + + ++ ++ + ++D Q++ K ++ EE+E L
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 205 EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
+ +T + KI ED++ L+ + + ++ E SD
Sbjct: 970 QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1012
Query: 263 ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
+EEE+ K +N ES E+ E S + ++ + +S FH
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1068
Query: 319 EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
EQ + I + KKE++ +A RL E+ + ++L + +
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1122
Query: 378 LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
L + R+A E+Q+ L +++ ++ E+E+ D + + E+E VL+
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1180
Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLE---EQYLGLALDVDRIKKDQEEE 488
+LD T S ++ ++ Q ++ AV L EQ+ ++D+ K+ E+E
Sbjct: 1181 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Score = 33.9 bits (76), Expect = 0.50
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 10 SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
+E A + N++LR +L E + ++ K K + L +A +++ + E + K
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1838
Query: 70 MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
+ K++KL E L Q E+ R QYK + QL+ +L E + S+ +N
Sbjct: 1839 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1898
Query: 126 HLQAL 130
+ + L
Sbjct: 1899 NRRKL 1903
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 53.9 bits (128), Expect = 5e-07
Identities = 110/500 (22%), Positives = 196/500 (39%), Gaps = 67/500 (13%)
Query: 22 EKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN-------E 74
E L L + Q+ KE+ Q+ RQ K EE + IK LR +
Sbjct: 1647 EHLTQDLERRDQELMLQKERI---QVLEDQRTRQTKI-LEEDLEQIKLSLRERGRELTTQ 1702
Query: 75 RQFKEEKLAE----QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQAL 130
RQ +E+ E Q L K+++ +E+E+ +E + E ++ L + LQ L
Sbjct: 1703 RQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGL 1762
Query: 131 ----------LTPDEPD-KSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVA 179
L+ E + Q LQE +G Q L +L D ++E
Sbjct: 1763 HRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEAL 1822
Query: 180 EKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDST 239
++ Q+ + +E + E+ + + +LE+ +T HG Q HK+ EE+
Sbjct: 1823 QQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL---QDHKEQARRLEEE----- 1874
Query: 240 LIGSSSHVEWEDAVHIIPENESDDEEEEEKG--PVSPRNLQESEEEEVP----QESWDEG 293
L V+ A+ + + + E+EK + + ++++E EV Q+SW +
Sbjct: 1875 LAVEGRRVQ---ALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQA 1931
Query: 294 YSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELL 353
+ L + L + ++ S + EE A + QEA G + L
Sbjct: 1932 QAVLKERDQELEALRAESQSSRHQEEAARARAEAL------------QEALGK--AHAAL 1977
Query: 354 DEKEPEVL-QDSLDRCYSTPSGCLELT-DSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQE 411
KE +L Q L R + L+ + D+CQ + + + E R+ D+ +YQE
Sbjct: 1978 QGKEQHLLEQAELSRSLEASTATLQASLDACQAH--SRQLEEALRIQEGEIQDQDLRYQE 2035
Query: 412 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQY 471
+ + + EL ++E E L + + E +LGQ EE+
Sbjct: 2036 DVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQERE------EEEI 2089
Query: 472 LGLALDVDRIKKDQEEEEDQ 491
GL V ++ ++E +
Sbjct: 2090 RGLHQSVRELQLTLAQKEQE 2109
Score = 47.0 bits (110), Expect = 6e-05
Identities = 51/193 (26%), Positives = 89/193 (46%), Gaps = 22/193 (11%)
Query: 11 EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
E E +E+ +L+ Q E + +E+ TQ L Q + + E L++ +
Sbjct: 878 ESLEREKMELEMRLKEQQTEMEAIQAQREEE--RTQAESALCQMQLETEKERVS-LLETL 934
Query: 71 LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT-----QLREKLREGRDASRSLNE 125
L+ +++ LA+ +Q E LRQ + +E+E T QL+E RE ++A+R +
Sbjct: 935 LQTQKE-----LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989
Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
L AL DLQ+Q+ + L LV + +D V+ EV EK++++
Sbjct: 990 DLAALQEESSSLLQDKMDLQKQVED---LKSQLVAQ------DDSQRLVEQEVQEKLRET 1040
Query: 186 SAPREMQKAEEKE 198
+QK E+E
Sbjct: 1041 QEYNRIQKELERE 1053
Score = 46.6 bits (109), Expect = 7e-05
Identities = 105/471 (22%), Positives = 184/471 (39%), Gaps = 90/471 (19%)
Query: 44 LTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQE 103
L +L +A+ Q + + E L + + ER+ + Q E L+ V AQ
Sbjct: 1315 LMELHETMASLQSRLRRAE---LQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQA 1371
Query: 104 RELTQLREKLREGRDASRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQ 156
L E LR R A + NE + QAL E +QG+ LQE LA LTQ
Sbjct: 1372 SAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLA---LLTQ 1428
Query: 157 HLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHG 216
L ++ +E+V+ + ++Q+ REMQKA +LE ++
Sbjct: 1429 TLAER---------EEEVET-LRGQIQELEKQREMQKA--------ALELLSLDLKK--- 1467
Query: 217 PYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRN 276
+ ++ +++++ E E ++ +E E+K V
Sbjct: 1468 --------RNQEVDLQQEQIQ----------ELEKCRSVLEHLPMAVQEREQKLTVQREQ 1509
Query: 277 LQESEEE-EVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQV---CMAVDI--GR 330
++E E++ E + + L +M+ +S L++Q V C+A+++
Sbjct: 1510 IRELEKDRETQRNVLEHQLLELEKKDQMI---ESQRGQVQDLKKQLVTLECLALELEENH 1566
Query: 331 HRWDQVKKEDQEATGPR------LSRELLD-EKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
H+ + +K +E G R L+ LD E+ + LQ + + S L
Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARE-- 1624
Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP-EVLQDSLDR 442
L+++ + ++IE+ Q +E R +EL+ +KE +VL+D R
Sbjct: 1625 --------LQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTR 1676
Query: 443 CYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 493
+ LE L SL E+ G L R + EE +GP
Sbjct: 1677 QTKILEEDLEQIKL---------SLRER--GRELTTQRQLMQERAEEGKGP 1716
Score = 39.7 bits (91), Expect = 0.009
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 34/217 (15%)
Query: 8 LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL-----AGFL------ANRQK 56
L +EK +++LE + + +LA+ QQ L++ + +L G L A R+
Sbjct: 921 LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQREL 980
Query: 57 KYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQ-LREKLRE 115
K + +D + + ++K+ Q KQ E+L+ V +R + Q ++EKLRE
Sbjct: 981 KEAARQHRDDLAALQEESSSLLQDKMDLQ-KQVEDLKSQLVAQDDSQRLVEQEVQEKLRE 1039
Query: 116 GRDASR--------------SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQK 161
++ +R SL E Q LL E D + Q+L L + + Q ++
Sbjct: 1040 TQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQEL-SALRQDMQEAQGEQKE 1098
Query: 162 LSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKE 198
LS + E ++ EV EK + +E Q EE E
Sbjct: 1099 LSAQM-----ELLRQEVKEK-EADFLAQEAQLLEELE 1129
Score = 35.8 bits (81), Expect = 0.13
Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 14/149 (9%)
Query: 11 EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECK-DLIKF 69
E+ E+ + + + L+ LA Q +E+ + L G + +K+ + ++ +L+
Sbjct: 1407 EQGELKVAQ-GKALQENLALLTQTLAEREEE--VETLRGQIQELEKQREMQKAALELLSL 1463
Query: 70 MLRNERQ---FKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLRE---GRDASRSL 123
L+ Q ++E++ E K L + V +E++LT RE++RE R+ R++
Sbjct: 1464 DLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV 1523
Query: 124 NEH-LQALLTPD---EPDKSQGQDLQEQL 148
EH L L D E + Q QDL++QL
Sbjct: 1524 LEHQLLELEKKDQMIESQRGQVQDLKKQL 1552
Score = 32.7 bits (73), Expect = 1.1
Identities = 60/221 (27%), Positives = 89/221 (40%), Gaps = 58/221 (26%)
Query: 8 LSSEKAEMNI-LEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKY-------- 58
L EKA + + L+ E+ R LAE+ Q + KE L + + F A +Q
Sbjct: 734 LVREKAALEVRLQAVERDRQDLAEQLQGLSSAKE---LLESSLFEAQQQNSVIEVTKGQL 790
Query: 59 -----KYEECKDLI-------KFMLRNERQFKEEK---LAEQLKQAEE-----LRQYKVL 98
+ K++I K L ER E++ A QL QAE+ L Q K
Sbjct: 791 EVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKA- 849
Query: 99 VHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHL 158
A E+E+ QLREK + R + H Q L E + + +L+ +L E
Sbjct: 850 --AHEKEVNQLREKWEKER------SWHQQELAKALESLEREKMELEMRLKE-------- 893
Query: 159 VQKLSPENDNDDDEDVQVE-VAEKVQKSSAPREMQKAEEKE 198
+ E +Q + E+ Q SA +MQ EKE
Sbjct: 894 --------QQTEMEAIQAQREEERTQAESALCQMQLETEKE 926
Score = 32.3 bits (72), Expect = 1.5
Identities = 93/460 (20%), Positives = 181/460 (39%), Gaps = 91/460 (19%)
Query: 14 EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN 73
E +LE+ EK + ++ Q ++LK++ L L ++ + EC+ + L
Sbjct: 1525 EHQLLEL-EKKDQMIESQRGQVQDLKKQ--LVTLECLALELEENHHKMECQQKLIKELEG 1581
Query: 74 ERQFKEEKLAEQL----KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 129
+R+ + L ++++EL+ +H E T L +L+E
Sbjct: 1582 QRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQER------------- 1628
Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 189
D+ KSQ +EQ+ E R +HL Q L D+++ ++ E++Q
Sbjct: 1629 ----DQEVKSQ----REQIEELQRQKEHLTQDLERR-----DQELMLQ-KERIQ----VL 1670
Query: 190 EMQKAEEKEVPEDSLEECAITCSN------------SHGPYDSNQPHKKTKITFEEDKVD 237
E Q+ + ++ E+ LE+ ++ + P K + + E K+
Sbjct: 1671 EDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKL- 1729
Query: 238 STLIGSSSHVE-WEDAVHIIPENESDDEEE-----EEKGPVSPRNLQESEEEEVPQESWD 291
L VE ++ +H + E + E++ + G S Q +E V Q+
Sbjct: 1730 -ILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQ 1788
Query: 292 EGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRE 351
E + + L S L+E Q +A + +++E Q+A G E
Sbjct: 1789 EAREQGELKEQSLQS---------QLDEAQRALAQ--RDQELEALQQEQQQAQG---QEE 1834
Query: 352 LLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQE 411
+ EK + LQ +L++ + T E Q ++ LE++ LA++ ++ +E
Sbjct: 1835 RVKEK-ADALQGALEQAHMT---LKERHGELQDHKEQARRLEEE---LAVEGRRVQALEE 1887
Query: 412 V-------EEDQDPSCPRLSRELLD-----EKEPEVLQDS 439
V +Q+ + L ++ + E E LQDS
Sbjct: 1888 VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDS 1927
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.0 bits (123), Expect = 2e-06
Identities = 133/663 (20%), Positives = 257/663 (38%), Gaps = 84/663 (12%)
Query: 11 EKAEMNILEINEKLRPQLAEKKQQFRN-----LKEKCFLTQLAGFLANRQKKYKYEECKD 65
++ E + E EK R Q E+++Q+R KE+ L + ++++ KY E ++
Sbjct: 938 QEEEQLLREEREKRRRQ--ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Query: 66 LIKF---MLRNERQFKEEKLAE-QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASR 121
L + +LR ER+ + + E Q ++ +EL+Q + + +ERE +L+E+ R+ R+
Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055
Query: 122 SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKL--SPENDNDDDEDVQVEVA 179
E Q L +E + + Q+L+ Q + L Q Q L PE + + Q
Sbjct: 1056 LQQEEEQ--LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 180 EKVQKSSAP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEED-K 235
E++Q+ E +K +E+ EE + +P K+ + E +
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEV--QQEEEQLLREEPEKRRRQELERQYR 1171
Query: 236 VDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWD---- 291
+ L + E+ E E EEEE R + +E++ W
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 292 ---------------EGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRW--- 333
E + L QS H L EQQ + R RW
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE-RDREQERRRWQQR 1289
Query: 334 -------DQVKKEDQEAT--GPRLSRE----LLDEKEPEVLQDSLDRCYSTPSGCLELTD 380
+Q+++E+Q+ R S+E L +E+E + + DR + L+ +
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 381 SCQPYRSAFYVLEQQRVGLAIDMDEIEKYQE-VEEDQDPSCPRLSRELLDEKE------- 432
QP R E+ R ++ E+ ++ +EE+Q R+ L E++
Sbjct: 1350 E-QPLRRQ----ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 433 PEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 492
+ L+ DR + L + + + + Q +R +K EEE+
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ--------ERERKFLEEEQQLR 1456
Query: 493 PPCPRLSRE----LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 548
R RE L E E ++ + DR + L + + + + +E
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 549 FSLDVGEIEKKGKGKK-RRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDS 607
F + ++ ++ + +K + + +++ RG++ +D + + E EE ++ +
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 608 LDR 610
DR
Sbjct: 1577 RDR 1579
Score = 47.4 bits (111), Expect = 4e-05
Identities = 79/357 (22%), Positives = 143/357 (40%), Gaps = 43/357 (12%)
Query: 21 NEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEE 80
++K R QL E++++ R+ T A Q + + + ++ + + R ER+ +
Sbjct: 871 DQKWRWQLEEERKRRRH-------TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Query: 81 KLAE-QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKS 139
+ E Q ++ E+L+Q + + +ERE + +E+ R+ R + + Q L +EP+K
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ--LLGEEPEKR 981
Query: 140 QGQDLQEQLAEGCRLTQHLVQKLSPE---------------NDNDDDEDVQVEVAEKVQK 184
+ Q+ +++ E L Q Q L E D E+ Q+ E+ ++
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 185 SSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSS 244
RE Q EE+E+ ++ + Q K+ ++ EE+++
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 245 SHVEWEDAVHIIPENESDDE----EEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
E E E + ++E EE EK Q EEEEV QE L
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE----EQLLREE 1157
Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKE 357
PE Q + EE Q +Q+ +E+QE R+ +E+E
Sbjct: 1158 PEK-RRRQELERQYREEEELQ---------QEEEQLLREEQEKRRQERERQYREEEE 1204
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 15/199 (7%)
Query: 8 LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
L E+ E + E+ R QL +++++ R + K + L R K+ + E +
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLK---REQEERLEQRLKREEVERLEQEE 614
Query: 68 KFMLRNERQFKEEKLAEQL---KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLN 124
+ R +R+ EE+ +QL ++ EE RQ ++ QER +L+ + E R R
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
Query: 125 EHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQK 184
EH E ++ + + +E+ + + + K + +++ D Q +V + +K
Sbjct: 675 EH--------EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR-QSKVYSRPRK 725
Query: 185 SSAPREMQKAEEKEVPEDS 203
R Q+ EEK +S
Sbjct: 726 QEGQRRRQEQEEKRRRRES 744
Score = 42.0 bits (97), Expect = 0.002
Identities = 103/535 (19%), Positives = 205/535 (38%), Gaps = 73/535 (13%)
Query: 54 RQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKL 113
R+ + + E+ + L + LR ERQ +EE+ ++L++ ++LR+ QE E + +E+
Sbjct: 269 RELQEEEEQLRKLERQELRRERQ-EEEQQQQRLRREQQLRR------KQEEERREQQEER 321
Query: 114 REGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDED 173
RE ++ E + L ++ ++ + Q +EQ E Q+L E + + E
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEE------RREQQLRREQEEERREQ 375
Query: 174 VQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEE 233
+ ++ RE Q E+++ + Q ++ + E
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEG 293
K + E E+ + E + E+E+ + L+ +EEE +E W
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQER---RKQQLKRDQEEE-RRERW--- 488
Query: 294 YSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELL 353
L + E EQQ R Q+++E +E RL R+
Sbjct: 489 ---LKLEEE-------------ERREQQ--------ERREQQLRREQEERREQRLKRQEE 524
Query: 354 DEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEV- 412
+E+ + L+ +L + R LEQ+R + ++ E+ ++
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKR-----LEQERREQRLKREQEERRDQLL 579
Query: 413 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP--SDYLELPDLGQPYSSAVYSLEEQ 470
+ +++ RL RE + E + ++ ++R L+ + + + EEQ
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 471 YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 530
+++++Q+E +Q RL RE E E L+ L R + E +
Sbjct: 640 E---ERRQQQLRREQQERREQ-----RLKRE----EEEERLEQRLKREHEEERREQELAE 687
Query: 531 SCQPYGSSF---------YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRR 576
Q + LE + V +K +G++RR + +K+RRR
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Score = 39.7 bits (91), Expect = 0.009
Identities = 92/447 (20%), Positives = 171/447 (38%), Gaps = 55/447 (12%)
Query: 8 LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
L E+ ++ LE E R + E++QQ R +E+ Q + K EE
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ-------------QLRRKQEE----- 312
Query: 68 KFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE-- 125
R E+Q + + E+ +Q EE R+ ++ +ER QLR + E R + E
Sbjct: 313 ---ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 126 ---HLQALLTPDEPDKSQGQDLQEQL--AEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
Q L + + Q ++QL + R Q L ++ + + Q+ +
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429
Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
+ ++ E ++ E++ E + ++ + ++ K EE++ + L
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQE---SWDEGYSTL 297
+E E+ E E+E+ + L+ EEEE Q+ S +
Sbjct: 490 -----KLEEEERREQQERREQQLRREQEER--REQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 298 SIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKE 357
E L + EQ++ + R DQ+ K ++E RL RE + E
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQE---ERRDQLLKREEERRQQRLKREQEERLE 599
Query: 358 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEV--EED 415
+ ++ ++R LE + + E++R L ++ E+ Q+ E
Sbjct: 600 QRLKREEVER--------LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
Query: 416 QDPSCPRLSRELLDEKEPEVLQDSLDR 442
Q+ RL R E+E E L+ L R
Sbjct: 652 QERREQRLKR----EEEEERLEQRLKR 674
Score = 38.5 bits (88), Expect = 0.020
Identities = 53/234 (22%), Positives = 103/234 (44%), Gaps = 44/234 (18%)
Query: 8 LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-------LANRQKKYKY 60
L ++ + LE +LR Q E++QQ R+ +++ F + L +++ K+
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQ--EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693
Query: 61 EECKDLI------KFMLRNERQFKEEKLAEQLKQAEELRQ-------------YKVLVHA 101
E + + + L+ E+Q + ++L + ++ E+LRQ K+L
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 102 Q---ERELTQLR--EKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQ 156
Q ERE QLR E+ R+ R+ + E + L E D+ + +EQL + +
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE--EEQLRQ-----E 1806
Query: 157 HLVQKLSPENDND----DDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEE 206
Q+L P+ + ++E +Q+E E+ + R+ + E+ E S E
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Score = 37.7 bits (86), Expect = 0.035
Identities = 72/371 (19%), Positives = 147/371 (39%), Gaps = 46/371 (12%)
Query: 11 EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
++ E L E+ R L E++Q R +++ F Q L +++ + K+ E + +
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE---LRSQEPERKFLEEEQQLHRQ 1527
Query: 71 LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREK---LREGRDASRSLNEHL 127
R + +EE+ + ++ ++ RQ + +E +L Q RE+ R+ RD L E
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 128 -------------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDD---D 171
+ L E + Q+ + E +L Q ++ + D +
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 172 EDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQ----PHKKT 227
E+ Q+ E+ Q+ R+ + EE+++ ++ E+ + Q ++
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 228 KITFEEDKVDSTLIGSSSHVE--------------WEDAVHIIPENESDDEEEEEKGPVS 273
K EE ++ + E E I+ E + E EE++
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Query: 274 PRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRW 333
R+ + EEE++ QE ++ + E ++ EEQQ+ G++RW
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRS----QESDRKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 334 --DQVKKEDQE 342
+Q++ E+QE
Sbjct: 1824 EEEQLQLEEQE 1834
Score = 34.3 bits (77), Expect = 0.38
Identities = 55/293 (18%), Positives = 112/293 (38%), Gaps = 42/293 (14%)
Query: 79 EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDK 138
+E L + +Q E+ R+++ E E Q R + R+ ++ + E ++ ++
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS-----EKQER 160
Query: 139 SQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKE 198
+ +D Q + E R Q ++ E ++E +Q + ++ ++++ E E
Sbjct: 161 LEQRDRQRRDEELWRQRQEWQER---EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217
Query: 199 VPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPE 258
+ EE Q ++ F+E++ EW ++ +
Sbjct: 218 LRRKGREE------------KQQQRRERQDRVFQEEE----------EKEWRKRETVLRK 255
Query: 259 NESDDEEEEEKGPVSPRNLQESEE-------EEVPQESWDEGYSTLSIPPEMLASYQSYS 311
E +EEE P R LQE EE +E+ +E +E + E +
Sbjct: 256 EEEKLQEEE---PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 312 STFHSLEE--QQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQ 362
EE +Q R Q+++E +E +L RE +E+ + L+
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Score = 33.9 bits (76), Expect = 0.50
Identities = 63/341 (18%), Positives = 135/341 (39%), Gaps = 47/341 (13%)
Query: 54 RQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKL 113
RQ+ K EE ++ + LR E+Q + E+ ++ ++ E L Q H +ER +L E+
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 114 RE-GRDASRSLNEHLQALLTPD----------EPDKSQGQDLQEQLAEGCRLTQHLVQ-- 160
+E R+ +S Q L + P K +GQ +++ E R + +Q
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 161 ------KLSPENDNDDDEDVQVEVAEKV----QKSSAPREMQKAEEKEVPEDSLEECAIT 210
+ E + D Q + EK Q+ SA +++ E+++ + ++
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ---- 805
Query: 211 CSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKG 270
+ + ++ + E +K + + ++ + + E E +E++E+
Sbjct: 806 -REQRFLPEEEEKEQRRRQRREREK-ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER- 862
Query: 271 PVSPRNLQESEEEE----VPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAV 326
R QE ++ +E TL P + + +EQQ+
Sbjct: 863 ----RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR---------KEQQLLQEE 909
Query: 327 DIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDR 367
+ R ++ K+ QE E L ++E ++L++ ++
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,127,182
Number of Sequences: 37866
Number of extensions: 1547033
Number of successful extensions: 13554
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 785
Number of HSP's that attempted gapping in prelim test: 8736
Number of HSP's gapped (non-prelim): 3228
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.