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Search of human proteins with 156523968
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156523968 poly (ADP-ribose) polymerase family, member 1
[Homo sapiens]
(1014 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 2028 0.0
gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 386 e-107
gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 386 e-107
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 244 3e-64
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 244 3e-64
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 114 4e-25
gi|73747844 ligase III, DNA, ATP-dependent isoform beta precurso... 54 7e-07
gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precurs... 54 7e-07
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 46 2e-04
gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo sapi... 43 0.001
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 40 0.009
gi|13124883 HsKin17 protein [Homo sapiens] 39 0.019
gi|32528306 replication factor C large subunit [Homo sapiens] 39 0.032
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 39 0.032
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 38 0.055
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 38 0.055
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 37 0.094
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 37 0.094
gi|115527120 nebulin [Homo sapiens] 37 0.094
gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo ... 37 0.12
gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo ... 36 0.16
gi|239757817 PREDICTED: similar to hCG1647425 [Homo sapiens] 36 0.21
gi|10190716 spindle pole body component 25 [Homo sapiens] 35 0.27
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 35 0.36
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 35 0.36
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 35 0.47
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap... 34 0.61
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi... 34 0.61
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 34 0.80
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 34 0.80
>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
sapiens]
Length = 1014
Score = 2028 bits (5254), Expect = 0.0
Identities = 1014/1014 (100%), Positives = 1014/1014 (100%)
Query: 1 MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKV 60
MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKV
Sbjct: 1 MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKV 60
Query: 61 GHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKS 120
GHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKS
Sbjct: 61 GHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKS 120
Query: 121 NRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQ 180
NRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQ
Sbjct: 121 NRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQ 180
Query: 181 LKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKA 240
LKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKA
Sbjct: 181 LKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKA 240
Query: 241 QNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSG 300
QNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSG
Sbjct: 241 QNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSG 300
Query: 301 QLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPE 360
QLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPE
Sbjct: 301 QLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPE 360
Query: 361 TSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLT 420
TSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLT
Sbjct: 361 TSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLT 420
Query: 421 GTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSP 480
GTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSP
Sbjct: 421 GTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSP 480
Query: 481 WGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLE 540
WGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLE
Sbjct: 481 WGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLE 540
Query: 541 HSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNK 600
HSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNK
Sbjct: 541 HSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNK 600
Query: 601 LEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPG 660
LEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPG
Sbjct: 601 LEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPG 660
Query: 661 TKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAV 720
TKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAV
Sbjct: 661 TKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAV 720
Query: 721 SQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRG 780
SQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRG
Sbjct: 721 SQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRG 780
Query: 781 GSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIE 840
GSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIE
Sbjct: 781 GSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIE 840
Query: 841 REGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADM 900
REGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADM
Sbjct: 841 REGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADM 900
Query: 901 VSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSA 960
VSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSA
Sbjct: 901 VSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSA 960
Query: 961 NISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014
NISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW
Sbjct: 961 NISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014
>gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform 2
[Homo sapiens]
Length = 570
Score = 386 bits (991), Expect = e-107
Identities = 216/516 (41%), Positives = 323/516 (62%), Gaps = 17/516 (3%)
Query: 512 KEEGINKSEKRMK-LTLKGGAAVDPDSGLE-HSAHVLEKGGKVFSATLGLVDIVKGTNSY 569
K+ +K ++ +K L LKG A VDP+ + AHV +G V+ L ++ N Y
Sbjct: 59 KDRTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKY 118
Query: 570 YKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK 629
Y +QLLEDD + + ++ WGRVG + + + + A E F K + +KT N W +
Sbjct: 119 YLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDR 178
Query: 630 N-FTKYPKKFYPLEIDYG---QDEEAVKK---LTVNPGTKSKLPKPVQDLIKMIFDVESM 682
F K P K+ L++DY QDEE KK L +S+L VQ+LIK+I +V++M
Sbjct: 179 EKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAM 238
Query: 683 KKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPH 742
++ M+E + + +K PLGKL+ QI+A Y L +++ + G +++ N FYT IPH
Sbjct: 239 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPH 298
Query: 743 DFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIK 802
DFG++ PPL+ + K+++L+ L DIE+A L++ S + P+D +Y L ++
Sbjct: 299 DFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ-SPEHPLDQHYRNLHCALR 357
Query: 803 VVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWH 862
+D +S E ++I +Y+++THA TH+ Y + ++D+F++E++GE + ++ + LHNR LLWH
Sbjct: 358 PLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWH 415
Query: 863 GSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLG 922
GSR +N+ GILS GLRIAPPEAP+TGYMFGKGIYFADM SKSANYC S+ GL+LL
Sbjct: 416 GSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLS 475
Query: 923 EVALGNMYELKHASHISK-LPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGV-- 979
EVALG EL A+ ++ L +GKHS KGLGK P + ++L+G VPLG +G+
Sbjct: 476 EVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILN 535
Query: 980 -NDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014
+ +L YNEYIVY+ QV ++YLLK++FNF LW
Sbjct: 536 PDGYTLNYNEYIVYNPNQVRMRYLLKVQFNF-LQLW 570
>gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform 1
[Homo sapiens]
Length = 583
Score = 386 bits (991), Expect = e-107
Identities = 215/508 (42%), Positives = 317/508 (62%), Gaps = 16/508 (3%)
Query: 519 SEKRMKLTLKGGAAVDPDSGLE-HSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLED 577
SE L LKG A VDP+ + AHV +G V+ L ++ N YY +QLLED
Sbjct: 80 SESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLED 139
Query: 578 DKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKN-FTKYPK 636
D + + ++ WGRVG + + + + A E F K + +KT N W + F K P
Sbjct: 140 DAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPG 199
Query: 637 KFYPLEIDYG---QDEEAVKK---LTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYE 690
K+ L++DY QDEE KK L +S+L VQ+LIK+I +V++M++ M+E +
Sbjct: 200 KYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMK 259
Query: 691 IDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPP 750
+ +K PLGKL+ QI+A Y L +++ + G +++ N FYT IPHDFG++ PP
Sbjct: 260 YNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPP 319
Query: 751 LLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEE 810
L+ + K+++L+ L DIE+A L++ S + P+D +Y L ++ +D +S E
Sbjct: 320 LIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ-SPEHPLDQHYRNLHCALRPLDHESYE 378
Query: 811 AEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFA 870
++I +Y+++THA TH+ Y + ++D+F++E++GE + ++ + LHNR LLWHGSR +N+
Sbjct: 379 FKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWV 436
Query: 871 GILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMY 930
GILS GLRIAPPEAP+TGYMFGKGIYFADM SKSANYC S+ GL+LL EVALG
Sbjct: 437 GILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCN 496
Query: 931 ELKHASHISK-LPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGV---NDTSLLY 986
EL A+ ++ L +GKHS KGLGK P + ++L+G VPLG +G+ + +L Y
Sbjct: 497 ELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNY 556
Query: 987 NEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014
NEYIVY+ QV ++YLLK++FNF LW
Sbjct: 557 NEYIVYNPNQVRMRYLLKVQFNF-LQLW 583
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform b
[Homo sapiens]
Length = 533
Score = 244 bits (623), Expect = 3e-64
Identities = 168/476 (35%), Positives = 263/476 (55%), Gaps = 33/476 (6%)
Query: 553 FSATLGLVDIVKGTNSYYKLQLLEDDKENRYWI-FRSWGRVGTVIGSNKLEQMPSKEDAI 611
++ TL +I N +Y +QLL+D NR++ + WGRVG V G +K+ EDA
Sbjct: 66 YNCTLNQTNIENNNNKFYIIQLLQDS--NRFFTCWNHWGRVGEV-GQSKINHFTRLEDAK 122
Query: 612 EHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQD-EEAVKKLTVNP-GTKSKLPKP 668
+ F K + EKT N W ++ F +P K+ +E+ + +EAV K+ P T +K +P
Sbjct: 123 KDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQP 182
Query: 669 ------VQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQ 722
Q LI IF E K M ++D++KMPLGKLSK+QI + L +++A+
Sbjct: 183 CSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKG 242
Query: 723 GSSDSQILD-LSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGG 781
+ Q L+ LS+ FYT+IPH+FG +PP +N+ + +QAK +ML L DIE+A +L
Sbjct: 243 PTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS 302
Query: 782 SDDSSKD----PIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIF 837
+ + + P+D +Y+ LK ++++D + E ++I+ Y++ T + H L+ I+
Sbjct: 303 EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIW 359
Query: 838 KIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYF 897
K+ +EGE R++ +L NR+LLWHG+ A IL+ GLRI P +G GKGIYF
Sbjct: 360 KVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYF 415
Query: 898 ADMVSKSANYCHTSQ--GDPIGLILLGEVALGNMYELKHAS-HISKLPKGKHSVKGLGKT 954
A SKSA Y + +G + LGEVALG + + + + P G SV G T
Sbjct: 416 ASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHT 475
Query: 955 TPDPS--ANISLDG--VDVPLGTGI-SSGVNDTSLLYNEYIVYDIAQVNLKYLLKL 1005
PDP+ + LDG V VP G + + ++ +EY++Y +Q L+YLL++
Sbjct: 476 EPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 531
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform a
[Homo sapiens]
Length = 540
Score = 244 bits (623), Expect = 3e-64
Identities = 168/476 (35%), Positives = 263/476 (55%), Gaps = 33/476 (6%)
Query: 553 FSATLGLVDIVKGTNSYYKLQLLEDDKENRYWI-FRSWGRVGTVIGSNKLEQMPSKEDAI 611
++ TL +I N +Y +QLL+D NR++ + WGRVG V G +K+ EDA
Sbjct: 73 YNCTLNQTNIENNNNKFYIIQLLQDS--NRFFTCWNHWGRVGEV-GQSKINHFTRLEDAK 129
Query: 612 EHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQD-EEAVKKLTVNP-GTKSKLPKP 668
+ F K + EKT N W ++ F +P K+ +E+ + +EAV K+ P T +K +P
Sbjct: 130 KDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQP 189
Query: 669 ------VQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQ 722
Q LI IF E K M ++D++KMPLGKLSK+QI + L +++A+
Sbjct: 190 CSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKG 249
Query: 723 GSSDSQILD-LSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGG 781
+ Q L+ LS+ FYT+IPH+FG +PP +N+ + +QAK +ML L DIE+A +L
Sbjct: 250 PTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS 309
Query: 782 SDDSSKD----PIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIF 837
+ + + P+D +Y+ LK ++++D + E ++I+ Y++ T + H L+ I+
Sbjct: 310 EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIW 366
Query: 838 KIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYF 897
K+ +EGE R++ +L NR+LLWHG+ A IL+ GLRI P +G GKGIYF
Sbjct: 367 KVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYF 422
Query: 898 ADMVSKSANYCHTSQ--GDPIGLILLGEVALGNMYELKHAS-HISKLPKGKHSVKGLGKT 954
A SKSA Y + +G + LGEVALG + + + + P G SV G T
Sbjct: 423 ASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHT 482
Query: 955 TPDPS--ANISLDG--VDVPLGTGI-SSGVNDTSLLYNEYIVYDIAQVNLKYLLKL 1005
PDP+ + LDG V VP G + + ++ +EY++Y +Q L+YLL++
Sbjct: 483 EPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 538
>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
sapiens]
Length = 1724
Score = 114 bits (286), Expect = 4e-25
Identities = 149/621 (23%), Positives = 257/621 (41%), Gaps = 97/621 (15%)
Query: 403 RNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDV 462
+ K +++ I++ GGK + + N I ++ +++ ++ + + DF+
Sbjct: 21 QQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQLNSIQKNHVHIANPDFIW-- 78
Query: 463 SASTKSLQELFLAHILS--PWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGI---- 516
KS++E L + + P+ +P+++ P + K S +VK EG+
Sbjct: 79 ----KSIREKRLLDVKNYDPY------KPLDITPPPDQ------KASSSEVKTEGLCPDS 122
Query: 517 -NKSEKRMKLTLKGGAAVD----PDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYK 571
+ E ++LT G V+ P + LEK G +V+
Sbjct: 123 ATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVE---------- 172
Query: 572 LQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNF 631
LQ D ++ + I + + + + EDA E+F EE + +
Sbjct: 173 LQCSRDSRDCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLR-- 230
Query: 632 TKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEI 691
+ F P E E+ L S L + V DL++MI+ +A+ E
Sbjct: 231 ----EHFTP-EATQLASEQLQALLLEEVMNSSTLSQEVSDLVEMIW-----AEALGHLEH 280
Query: 692 DLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPL 751
L K P+ ++S + A IL V+ A+ G + Q+ + FY LIPH M K
Sbjct: 281 MLLK-PVNRISLNDVSKAEGILLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEV- 338
Query: 752 LNNADSVQAKVEMLDNLLD-IEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEE 810
N + K ++ + D + V + L P Y L+ I+ V++++EE
Sbjct: 339 --NLGLLAKKADLCQLIRDMVNVCETNL-----SKPNPPSLAKYRALRCKIEHVEQNTEE 391
Query: 811 AEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFA 870
+RK V H H+ ++V+ IF++ R E + +L N R L HGS N
Sbjct: 392 FLRVRKEVLQNH---HSKSPVDVLQIFRVGRVNETTEF--LSKLGNVRPLLHGSPVQNIV 446
Query: 871 GILSQGLRIAPPEAPVTGYM------FGKGIYFADMVSKSANYCHTSQGDPIGLILLGEV 924
GIL +GL + P G G GIYF+D +S S Y H + D L+L+ +V
Sbjct: 447 GILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDV 505
Query: 925 ALGNMYELKHAS-HISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTS 983
ALG +L +++ P G SV G+ +T A+++ D D
Sbjct: 506 ALGKCMDLHEKDFSLTEAPPGYDSVHGVSQT-----ASVTTDFED--------------- 545
Query: 984 LLYNEYIVYDIAQVNLKYLLK 1004
+E++VY QV +KY++K
Sbjct: 546 ---DEFVVYKTNQVKMKYIIK 563
>gi|73747844 ligase III, DNA, ATP-dependent isoform beta precursor
[Homo sapiens]
Length = 949
Score = 53.9 bits (128), Expect = 7e-07
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 3 ESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFD--GKVPHWYHFSCFWKV 60
E +++ + V+YAK G A CKKC E I K R+ +V +P + G + WYH C ++
Sbjct: 87 EMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEK 146
Query: 61 GHSIRHPDVEVDGFSELR-WDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTL 110
R +++ +EL W++ + +K + G+ +K +
Sbjct: 147 LERARATTKKIEDLTELEGWEELEDNEKEQITQHIADLSSKAAGTPKKKAV 197
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 113 FAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVK--NREEL 170
F +YAK + CK C EKI KG R+ K + +P G + WYH C + R
Sbjct: 93 FCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARA 152
Query: 171 GFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSE 205
+ ++L+G+ L +KE + + + + S+
Sbjct: 153 TTKKIEDLTELEGWEELEDNEKEQITQHIADLSSK 187
>gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precursor
[Homo sapiens]
Length = 1009
Score = 53.9 bits (128), Expect = 7e-07
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 3 ESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFD--GKVPHWYHFSCFWKV 60
E +++ + V+YAK G A CKKC E I K R+ +V +P + G + WYH C ++
Sbjct: 87 EMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEK 146
Query: 61 GHSIRHPDVEVDGFSELR-WDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTL 110
R +++ +EL W++ + +K + G+ +K +
Sbjct: 147 LERARATTKKIEDLTELEGWEELEDNEKEQITQHIADLSSKAAGTPKKKAV 197
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 113 FAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVK--NREEL 170
F +YAK + CK C EKI KG R+ K + +P G + WYH C + R
Sbjct: 93 FCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARA 152
Query: 171 GFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSE 205
+ ++L+G+ L +KE + + + + S+
Sbjct: 153 TTKKIEDLTELEGWEELEDNEKEQITQHIADLSSK 187
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 46.2 bits (108), Expect = 2e-04
Identities = 63/237 (26%), Positives = 87/237 (36%), Gaps = 57/237 (24%)
Query: 792 VNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDL----EVIDIFKIE----REG 843
VN + D+ D++ + E + H NA + VI I K+ RE
Sbjct: 1102 VNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRER 1161
Query: 844 ECQRYKPFKQL----HNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFAD 899
C R K + HN R+L+HGS N I+ +G G MFG GIYFA+
Sbjct: 1162 FCHRQKEVSEENHNHHNERMLFHGSPFIN--AIIHKGF---DERHAYIGGMFGAGIYFAE 1216
Query: 900 MVSKSANY---------CHTSQGDPIGL----ILLGEVALGNMYELKHASHISKLPKGKH 946
SKS Y C T + + +L V LG + ++ P G H
Sbjct: 1217 NSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHH 1276
Query: 947 SVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLL 1003
SV G PS N L Y EY++Y Q +YL+
Sbjct: 1277 SVIG------RPSVN---------------------GLAYAEYVIYRGEQAYPEYLI 1306
>gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo
sapiens]
Length = 1522
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/302 (20%), Positives = 116/302 (38%), Gaps = 26/302 (8%)
Query: 193 EALKK-QLPGVKS----EGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWN 247
EA KK LP V E R G D + + +K+E+ ++++ + +D +
Sbjct: 706 EAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSTKEERSLETEITNGINLNSDTAEH 765
Query: 248 ----IKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCE-----EC 298
++ K V + D+ F + + S +VA G L E +
Sbjct: 766 PGTRLQTHRKTVVTPLDMNR---FQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDT 822
Query: 299 SGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFP 358
+ + K + + DV + +TP R + ++ + + L ++ VK
Sbjct: 823 PSKFLSKDKLFKPSFDVK---DALAALETPGRP---SQQKRKPSTPLSEVIVKNLQLALA 876
Query: 359 PETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGK 418
+ +VA + P A + A KPL + + KLS+ + E+ + LG
Sbjct: 877 NSSRNAVALSASPQLKEAQS---EKEEAPKPLHKVVVCVSKKLSKKQSELNGIAASLGAD 933
Query: 419 LTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHIL 478
+ ++ + N++ + VKE + +VSE +L D + K L E H
Sbjct: 934 YRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTY 993
Query: 479 SP 480
+P
Sbjct: 994 NP 995
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 40.4 bits (93), Expect = 0.009
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 18/108 (16%)
Query: 856 NRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCH---TSQ 912
N R+L+HGS N I+ +G G MFG GIYFA+ SKS Y +
Sbjct: 1025 NERMLFHGSPFVN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGT 1079
Query: 913 GDPI----------GLILLGEVALGNMYELKHASHISKLPKGKHSVKG 950
G P+ +L V LG + A ++ P G HSV G
Sbjct: 1080 GCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTG 1127
>gi|13124883 HsKin17 protein [Homo sapiens]
Length = 393
Score = 39.3 bits (90), Expect = 0.019
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 59 KVGHSIRHPDVEVDGFSEL-RWDDQQKV-----KKTAEAGGVTGKGQDGIGSKAEKTLGD 112
+V + + EV F+EL R +D++KV K + G T +G A KT+G
Sbjct: 176 QVRRGLEGKEQEVPTFTELSRENDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGS 235
Query: 113 FAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVK 165
A+ K + + EK +K ++ EK + D W P VK
Sbjct: 236 SASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVK 288
>gi|32528306 replication factor C large subunit [Homo sapiens]
Length = 1147
Score = 38.5 bits (88), Expect = 0.032
Identities = 53/241 (21%), Positives = 97/241 (40%), Gaps = 29/241 (12%)
Query: 313 GDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKK---LKVKKQDRIFPPETSASVA--- 366
G+V++ K K RKE + KE ++ +K +K+K + + P +T +S A
Sbjct: 308 GEVSS-PKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKT-PKKTKSSPAKKE 365
Query: 367 -ATPPPS--------------TASAPAAVNSSA---SADKPLSNMKILTLGKL-SRNKDE 407
+P S P A+ S A+ L + + G L S +DE
Sbjct: 366 SVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDE 425
Query: 408 VKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTK 467
K++IE+ GGK+TG +K + + + + K ++ +++ ED L ++ +
Sbjct: 426 AKSLIERYGGKVTGNVSKKTNYLVMGR--DSGQSKSDKAAALGTKIIDEDGLLNLIRTMP 483
Query: 468 SLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTL 527
+ + + + E K E +GK + SKK K +K + K
Sbjct: 484 GKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIK 543
Query: 528 K 528
K
Sbjct: 544 K 544
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 38.5 bits (88), Expect = 0.032
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 146 PEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSE 205
P L I + + G KN+ L E QLK E+KE LK++ K E
Sbjct: 313 PTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLK--LRAEREEKEKLKEEAKRAKEE 370
Query: 206 GKRKGDEVDGVDEVAKKKSKKEKDKDSKLEK 236
K+K +E + E +++ K+EKD+ K EK
Sbjct: 371 AKKKKEEEKELKE-KERREKREKDEKEKAEK 400
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 37.7 bits (86), Expect = 0.055
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 336 PKEFREISYLKKLK-------VKKQDRIFPPETSASVAATPPPSTASAP-----AAVNSS 383
P + ++ +KL+ K D P + S A PPP+ AP ++ +SS
Sbjct: 434 PPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSS 493
Query: 384 ASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEK-MNKK 442
+ +D + + +L+ ++++KA+ E+L NK KKE +K +K+
Sbjct: 494 SDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKR 553
Query: 443 MEEVKE 448
EEV+E
Sbjct: 554 KEEVEE 559
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 37.7 bits (86), Expect = 0.055
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 336 PKEFREISYLKKLK-------VKKQDRIFPPETSASVAATPPPSTASAP-----AAVNSS 383
P + ++ +KL+ K D P + S A PPP+ AP ++ +SS
Sbjct: 434 PPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSS 493
Query: 384 ASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEK-MNKK 442
+ +D + + +L+ ++++KA+ E+L NK KKE +K +K+
Sbjct: 494 SDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKR 553
Query: 443 MEEVKE 448
EEV+E
Sbjct: 554 KEEVEE 559
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 37.0 bits (84), Expect = 0.094
Identities = 23/74 (31%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
Query: 195 LKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSK---LEKALKAQNDLIWNI--K 249
L++++ K E + EVD + E+ K+ ++ DKD K LE+ +K QN + N+ K
Sbjct: 740 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHK 799
Query: 250 DELKKVCSTNDLKE 263
++++K S L+E
Sbjct: 800 EQVEKKKSAQMLEE 813
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 37.0 bits (84), Expect = 0.094
Identities = 23/74 (31%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
Query: 195 LKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSK---LEKALKAQNDLIWNI--K 249
L++++ K E + EVD + E+ K+ ++ DKD K LE+ +K QN + N+ K
Sbjct: 712 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHK 771
Query: 250 DELKKVCSTNDLKE 263
++++K S L+E
Sbjct: 772 EQVEKKKSAQMLEE 785
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 37.0 bits (84), Expect = 0.094
Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
Query: 165 KNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKS 224
K E+ +R ++ G S+L D E KK + S+ K + + D+ K K+
Sbjct: 5753 KQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAK-LSSQVKYR----ENFDK-EKGKT 5806
Query: 225 KKEKDKDSKLEKALKAQNDLIWNI--KDELKKVCS-TNDLKELLIFN 268
K KDS+L K +K N+L + K +LKK+ D+KE LI N
Sbjct: 5807 PKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIMN 5853
>gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo
sapiens]
Length = 630
Score = 36.6 bits (83), Expect = 0.12
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 847 RYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAP-PEAPVTGYMFGKGIYFADMVSKSA 905
R++ K+L+ +HGS N+ IL GL A + + G +GKGIY + + S S
Sbjct: 458 RFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISF 517
Query: 906 NYCHTSQG 913
Y +G
Sbjct: 518 GYSGMGKG 525
>gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo
sapiens]
Length = 854
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 848 YKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAP-PEAPVTGYMFGKGIYFADMVSKSAN 906
++ K+L +HGS N+ IL GL +A + G M+G GIY + M S S
Sbjct: 683 FRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFG 742
Query: 907 Y 907
Y
Sbjct: 743 Y 743
>gi|239757817 PREDICTED: similar to hCG1647425 [Homo sapiens]
Length = 227
Score = 35.8 bits (81), Expect = 0.21
Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 20/159 (12%)
Query: 105 KAEKTLGDFAAEYAKSN----RSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWY-- 158
+A++ LGD A KS+ +ST + + ++ + ++ K DP P+ + +
Sbjct: 45 RAKQALGDSALLKKKSSTQMLQSTSQSFLRSAQRAETKM--KFEDPNAPKSPPLAFFMFS 102
Query: 159 ---------HPGCFVKN-REELGFRPEYSASQLKG-FSLLATEDKEALKKQLPGVKSEGK 207
HPG + + ++LG Y A K + A + KE +K + +GK
Sbjct: 103 SEDCPKIKEHPGLSISDVAKKLGEMWNYIAEDDKHPYEKKAVKLKEKYEKDIAAFGGKGK 162
Query: 208 RKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIW 246
+ G + K K KKE+DK ++ A N L+W
Sbjct: 163 PDAAK-KGAIKAEKCKKKKEEDKMRNMKIKKMATNCLVW 200
>gi|10190716 spindle pole body component 25 [Homo sapiens]
Length = 224
Score = 35.4 bits (80), Expect = 0.27
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 405 KDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSE--DFLQDV 462
KD +KA EKL KL + + + ++ + NK ++E K+ +++++E Q++
Sbjct: 37 KDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQEL 96
Query: 463 SASTKSLQEL 472
T ++Q+L
Sbjct: 97 EVLTANIQDL 106
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 35.0 bits (79), Expect = 0.36
Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 18/143 (12%)
Query: 129 MEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLA 188
+E +K + +L K + + + M+DR H ++RE+ + + + LL
Sbjct: 418 LENSDKEKRQLQKTVAEQDMKMNDMLDRIKH-----QHREQGSIKCKLEEDLQEATKLL- 471
Query: 189 TEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNI 248
EDK ++QL K K E++ + + KKK K K+ KLE+ +N+ N+
Sbjct: 472 -EDK---REQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEE----ENE---NL 520
Query: 249 KDELKKVCSTNDLKELLIFNKQQ 271
+ EL + CST L +N Q
Sbjct: 521 RAEL-QCCSTQLESSLNKYNTSQ 542
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 35.0 bits (79), Expect = 0.36
Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 18/143 (12%)
Query: 129 MEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLA 188
+E +K + +L K + + + M+DR H ++RE+ + + + LL
Sbjct: 563 LENSDKEKRQLQKTVAEQDMKMNDMLDRIKH-----QHREQGSIKCKLEEDLQEATKLL- 616
Query: 189 TEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNI 248
EDK ++QL K K E++ + + KKK K K+ KLE+ +N+ N+
Sbjct: 617 -EDK---REQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEE----ENE---NL 665
Query: 249 KDELKKVCSTNDLKELLIFNKQQ 271
+ EL + CST L +N Q
Sbjct: 666 RAEL-QCCSTQLESSLNKYNTSQ 687
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 34.7 bits (78), Expect = 0.47
Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
Query: 162 CFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAK 221
C V+NR EL +Q+ L + ++ ++ P ++ E +K +E K
Sbjct: 190 CIVRNRNELAETLALLKAQIDPVLLKNSSQQDNSSRESPSLEDEETKK------EEETPK 243
Query: 222 KKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELL 265
++ +KE +K E+ + +N N+ +E D KEL+
Sbjct: 244 QEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELV 287
Score = 30.4 bits (67), Expect = 8.8
Identities = 42/188 (22%), Positives = 78/188 (41%), Gaps = 22/188 (11%)
Query: 349 KVKKQDRIFPPETSASVAATP---PPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNK 405
K++K + F + + ++ P P ST + + A+ P SN+ I KL+ K
Sbjct: 587 KLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNI-IDHCEKLASEK 645
Query: 406 DEVKAM-IEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSA 464
+ V+ +GG+ + K L E K + + +V+ N+ +++ S
Sbjct: 646 EVVECQSTSTVGGQ---SVKKVDL------ETLKEDSEFTKVEMDNLDNAQTSGIEEPSE 696
Query: 465 STKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKE--------EGI 516
+ S+Q+ + L P +E E+ + R K G L+ + + K+ E
Sbjct: 697 TKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPE 756
Query: 517 NKSEKRMK 524
NK EK K
Sbjct: 757 NKQEKTEK 764
>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
sapiens]
Length = 698
Score = 34.3 bits (77), Expect = 0.61
Identities = 15/67 (22%), Positives = 32/67 (47%)
Query: 190 EDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIK 249
+ K LK L ++ G + + G+ + + S + ++ E+AL+ DL+ N+
Sbjct: 267 QHKALLKVDLAAFQTRGNQLCSLISGIIRASSESSYPTAESQAEAERALREMRDLLMNLG 326
Query: 250 DELKKVC 256
E+ + C
Sbjct: 327 QEITRAC 333
>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
sapiens]
Length = 659
Score = 34.3 bits (77), Expect = 0.61
Identities = 15/67 (22%), Positives = 32/67 (47%)
Query: 190 EDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIK 249
+ K LK L ++ G + + G+ + + S + ++ E+AL+ DL+ N+
Sbjct: 267 QHKALLKVDLAAFQTRGNQLCSLISGIIRASSESSYPTAESQAEAERALREMRDLLMNLG 326
Query: 250 DELKKVC 256
E+ + C
Sbjct: 327 QEITRAC 333
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 33.9 bits (76), Expect = 0.80
Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 8/100 (8%)
Query: 323 VKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNS 382
V T T E + + SY L ++K R P T+A TP P VNS
Sbjct: 55 VNTDTMTHLE--AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNS 112
Query: 383 SASAD-KPLSNMKILTLGKLSRNKD-EVKAMIEKLGGKLT 420
A+AD + N L LS +K EVK LGGK T
Sbjct: 113 PANADYQERFNPSALKDSALSTHKPIEVKG----LGGKAT 148
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 33.9 bits (76), Expect = 0.80
Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 8/100 (8%)
Query: 323 VKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNS 382
V T T E + + SY L ++K R P T+A TP P VNS
Sbjct: 55 VNTDTMTHLE--AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNS 112
Query: 383 SASAD-KPLSNMKILTLGKLSRNKD-EVKAMIEKLGGKLT 420
A+AD + N L LS +K EVK LGGK T
Sbjct: 113 PANADYQERFNPSALKDSALSTHKPIEVKG----LGGKAT 148
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,172,448
Number of Sequences: 37866
Number of extensions: 1765705
Number of successful extensions: 7146
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 6908
Number of HSP's gapped (non-prelim): 310
length of query: 1014
length of database: 18,247,518
effective HSP length: 112
effective length of query: 902
effective length of database: 14,006,526
effective search space: 12633886452
effective search space used: 12633886452
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.