TOPBP1 11095

Name: TOPBP1	Sequence: fasta or formatted (1522aa)		NCBI GI: 194440660
Description: topoisomerase (DNA) II binding protein 1		Referenced in: DNases, Recombination, and DNA Repair Replication Proteins
Composition: Amino acid Percentage Count Longest homopolymer A alanine 6.3 96 3 C cysteine 2.4 37 1 D aspartate 4.5 69 2 E glutamate 8.3 126 3 F phenylalanine 3.3 50 2 G glycine 4.6 70 3 H histidine 3.0 45 2 I isoleucine 5.1 77 2 K lysine 7.6 115 3 L leucine 9.0 137 2 M methionine 1.4 22 2 N asparagine 4.9 75 2 P proline 5.5 84 2 Q glutamine 4.9 75 2 R arginine 4.5 69 2 S serine 9.3 142 3 T threonine 5.3 80 2 V valine 6.6 101 3 W tryptophan 1.1 17 1 Y tyrosine 2.3 35 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 topoisomerase (DNA) II binding protein 1 ECT2 0.034 epithelial cell transforming sequence 2 oncogene pro... ANKRD32 0.018 ankyrin repeat domain 32 PAXIP1 0.015 PAX interacting protein 1 MCPH1 0.012 microcephalin XRCC1 0.007 X-ray repair cross complementing protein 1 PARP1 0.006 poly (ADP-ribose) polymerase family, member 1 [Homo... SPEN 0.005 spen homolog, transcriptional regulator CLIP1 0.005 restin isoform b CLIP1 0.005 restin isoform a PCLO 0.005 piccolo isoform 2 PCLO 0.005 piccolo isoform 1 MLL2 0.005 myeloid/lymphoid or mixed-lineage leukemia 2 REV1 0.004 REV1-like isoform 2 REV1 0.004 REV1-like isoform 1 CEP170 0.004 centrosomal protein 170kDa isoform beta CEP170 0.004 centrosomal protein 170kDa isoform alpha CEP170 0.004 centrosomal protein 170kDa isoform gamma VCPIP1 0.003 valosin containing protein (p97)/p47 complex interac... CEP152 0.003 centrosomal protein 152kDa SFMBT1 0.003 Scm-like with four mbt domains 1 SFMBT1 0.003 Scm-like with four mbt domains 1 SFMBT1 0.003 Scm-like with four mbt domains 1 DPCR1 0.003 diffuse panbronchiolitis critical region 1 protein ... LOC100294236 0.003 PREDICTED: similar to diffuse panbronchiolitis crit... SYNM 0.003 desmuslin isoform A PALMD 0.003 palmdelphin MYC 0.003 myc proto-oncogene protein MLL4 0.003 myeloid/lymphoid or mixed-lineage leukemia 4 MUC21 0.003 mucin 21 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.