Guide to the Human Genome
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Name: PARP1 Sequence: fasta or formatted (1014aa) NCBI GI: 156523968
Description:

poly (ADP-ribose) polymerase family, member 1

Referenced in:

DNases, Recombination, and DNA Repair
polyADP-Ribose Polymerase Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         67           2
 C cysteine            1.4         14           1
 D aspartate           6.1         62           2
 E glutamate           7.4         75           2
 F phenylalanine       3.0         30           1
 G glycine             7.0         71           2
 H histidine           1.9         19           1
 I isoleucine          4.7         48           2
 K lysine             12.4        126           3
 L leucine             8.9         90           2
 M methionine          2.5         25           1
 N asparagine          3.6         36           2
 P proline             4.3         44           3
 Q glutamine           3.4         34           2
 R arginine            3.3         33           2
 S serine              8.4         85           2
 T threonine           4.1         42           2
 V valine              6.7         68           2
 W tryptophan          1.3         13           1
 Y tyrosine            3.2         32           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   poly (ADP-ribose) polymerase family, member 1 [Homo... 
PARP2                 0.180   poly (ADP-ribose) polymerase family, member 2 isofo...
PARP2                 0.180   poly (ADP-ribose) polymerase family, member 2 isofo...
PARP3                 0.109   poly (ADP-ribose) polymerase family, member 3 isofo...
PARP3                 0.109   poly (ADP-ribose) polymerase family, member 3 isofo...
PARP4                 0.044   poly (ADP-ribose) polymerase family, member 4 [Homo...
LIG3                  0.014   ligase III, DNA, ATP-dependent isoform beta precurso...
LIG3                  0.014   ligase III, DNA, ATP-dependent isoform alpha precurs...
TNKS                  0.010   tankyrase, TRF1-interacting ankyrin-related ADP-ribo...
TOPBP1                0.009   topoisomerase (DNA) II binding protein 1 
TNKS2                 0.007   tankyrase, TRF1-interacting ankyrin-related ADP-ribo...
KIN                   0.007   HsKin17 protein 
RFC1                  0.007   replication factor C large subunit 
CHAF1A                0.007   chromatin assembly factor 1, subunit A (p150) 
BRD4                  0.006   bromodomain-containing protein 4 isoform short 
BRD4                  0.006   bromodomain-containing protein 4 isoform long 
ERC1                  0.006   RAB6-interacting protein 2 isoform epsilon 
ERC1                  0.006   RAB6-interacting protein 2 isoform delta 
NEB                   0.006   nebulin 
PARP6                 0.006   poly (ADP-ribose) polymerase family, member 6 
PARP8                 0.005   poly (ADP-ribose) polymerase family, member 8 
LOC644129             0.005   PREDICTED: similar to hCG1647425 
SPC25                 0.005   spindle pole body component 25 
PMFBP1                0.005   polyamine modulated factor 1 binding protein 1 isof...
PMFBP1                0.005   polyamine modulated factor 1 binding protein 1 isof...
RSF1                  0.005   remodeling and spacing factor 1 
GLE1                  0.004   GLE1 RNA export mediator homolog isoform 1 
GLE1                  0.004   GLE1 RNA export mediator homolog isoform 2 
LDB3                  0.004   LIM domain binding 3 isoform 4 
LDB3                  0.004   LIM domain binding 3 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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