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Search of human proteins with 156415994
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156415994 UTP11-like, U3 small nucleolar ribonucleoprotein
[Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156415994 UTP11-like, U3 small nucleolar ribonucleoprotein [H... 498 e-141
gi|146260271 hypothetical protein LOC129881 [Homo sapiens] 46 3e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 1e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 41 0.001
gi|65507253 hypothetical protein LOC55196 [Homo sapiens] 40 0.001
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 40 0.003
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 40 0.003
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 40 0.003
gi|148746195 trichohyalin [Homo sapiens] 39 0.003
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 38 0.007
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 38 0.007
gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens] 38 0.007
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 38 0.010
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 38 0.010
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 37 0.022
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 37 0.022
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 36 0.028
gi|33469933 phospholipase C beta 4 isoform a [Homo sapiens] 36 0.028
gi|33469939 phospholipase C beta 4 isoform b [Homo sapiens] 36 0.028
gi|13027602 DDRGK domain containing 1 [Homo sapiens] 36 0.028
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 36 0.028
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 36 0.037
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 36 0.037
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 36 0.037
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 35 0.048
gi|38044112 restin isoform b [Homo sapiens] 35 0.048
gi|4506751 restin isoform a [Homo sapiens] 35 0.048
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 35 0.048
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 35 0.048
gi|116174778 centrosome spindle pole associated protein 1 isofor... 35 0.048
>gi|156415994 UTP11-like, U3 small nucleolar ribonucleoprotein [Homo
sapiens]
Length = 253
Score = 498 bits (1283), Expect = e-141
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALE 60
MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALE
Sbjct: 1 MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALE 60
Query: 61 KNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLK 120
KNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLK
Sbjct: 61 KNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLK 120
Query: 121 SELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVK 180
SELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVK
Sbjct: 121 SELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVK 180
Query: 181 GVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVN 240
GVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVN
Sbjct: 181 GVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVN 240
Query: 241 SPAIYKFQSRRKR 253
SPAIYKFQSRRKR
Sbjct: 241 SPAIYKFQSRRKR 253
>gi|146260271 hypothetical protein LOC129881 [Homo sapiens]
Length = 552
Score = 46.2 bits (108), Expect = 3e-05
Identities = 60/248 (24%), Positives = 112/248 (45%), Gaps = 30/248 (12%)
Query: 4 AFRKAAKSRQREHRERSQPG------FRKHLGLLEKKKDYKLRADDYRKKQEYLKALR-K 56
AF++ + ++ HRER ++H E++K Y+ + + K+Q L + +
Sbjct: 196 AFKEEQEKAEKRHRERVALAKDHLKQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMR 255
Query: 57 KALEKNPDEFYYKMTRV--KLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAK 114
K LEK +E + R +QD HIIK +++ E+ + MR K+I+ K+
Sbjct: 256 KKLEKKREEMHESRRRFLEHMQDK-HIIKAVEQQQQEEEDEKMR----KFIKAKKRLIQM 310
Query: 115 KIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETL 174
E+ ++E H L + +++ H F + KE L ++ R E
Sbjct: 311 GKEK-EAETHRL-MEKRRERIHNFLSELLKE--------KLDNEDMIIARDIAEAEAEWE 360
Query: 175 QKEKVKGVTNQTGLKRIAKER-----QKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKT 229
++E+ K N+ LK IA+ R K+ ++IE +++L + + Q + +K
Sbjct: 361 KREREKDEKNKAELKTIAEYRAIVMKNKEEEERQRKIEAKEQLLAVMKADQIFWE-HEKE 419
Query: 230 QKVKVKKE 237
+K K KE
Sbjct: 420 KKCKADKE 427
Score = 29.3 bits (64), Expect = 3.4
Identities = 42/212 (19%), Positives = 84/212 (39%), Gaps = 46/212 (21%)
Query: 6 RKAAKSRQREHRERSQPGFRKHLGLLEKKKDYK----LRADDYRKKQEYLKALRKKALEK 61
R+ ++++ S+ +L LL K D + + D++++ Q+ L L ++A
Sbjct: 13 RRCGRAKESTEIRNSEEDQVLYLPLLPSKVDLQQVTIIPHDEWKRIQDSLDRLTREAACL 72
Query: 62 NPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKS 121
+ K ++ Q+ V T + ++L+ A+ K+ E +++
Sbjct: 73 RAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLE---------------AKKKRDEEIEA 117
Query: 122 ELHLLDFQGK--QQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKV 179
E +LD + + +Q K KK +E N + + Q E+V
Sbjct: 118 ERQILDLEEEIYKQGKR------KKAIE-------------------NAKQYQFYQTERV 152
Query: 180 KGVTNQTGLKRIAKERQKQYNCLTQRIEREKK 211
K + L R+ KER Q +I+ +KK
Sbjct: 153 KNFHSGLLLSRVMKERDAQIEFRKSKIKSDKK 184
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 44.3 bits (103), Expect = 1e-04
Identities = 48/233 (20%), Positives = 107/233 (45%), Gaps = 23/233 (9%)
Query: 12 RQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMT 71
++ + RE+ + +R+ L E++K + + R ++E + ++ EK
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE-------- 411
Query: 72 RVKLQDGV--HIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQ 129
R++ Q+ + + K +E+ EQ K R Q+ K E +R+ E +K R + E +
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEE 471
Query: 130 GKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETL------QKEKVKGVT 183
Q+ + + +KE +Q Q PE ++++ + +++ Q+EK++
Sbjct: 472 KMQKQEENMWEQEEKEWQQ-------QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 184 NQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKK 236
G ++ ++K Q E+E+K+ QK+ +++ M+K + + KK
Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Score = 33.5 bits (75), Expect = 0.18
Identities = 37/215 (17%), Positives = 112/215 (52%), Gaps = 14/215 (6%)
Query: 30 LLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETK--- 86
LL + + L+ + +R+++E + ++K + K ++ + + R++ Q+G +E K
Sbjct: 261 LLPQVQTNTLQEEMWRQEEELRE--QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWR 318
Query: 87 -EEVTPEQLKLMRTQDVKYIEMKRVAEAKK-IERLKSELHLLDFQGKQQNKHVFFFDTKK 144
E+ EQ K +R Q+ + E K + E ++ ++ + ++ + + ++Q + ++ + +
Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 145 EVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQ 204
++ + Q + +R++ + E L++++ + + +++ K R+++ +
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQD--ERLREKEERMREQEKMWEQVEKMREEK-----K 431
Query: 205 RIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETV 239
E+EKK +K+Q + + ++ +K++ ++ET+
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Score = 31.6 bits (70), Expect = 0.69
Identities = 39/245 (15%), Positives = 117/245 (47%), Gaps = 19/245 (7%)
Query: 6 RKAAKSRQREHRERSQPG-FRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPD 64
R+ K +++E + R Q ++ + E++K + + R+++E ++ + E+
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 65 EFYYKMT---RVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKS 121
E+ + + KL + + + +EE EQ + +R Q+ + + K++ +K+ +
Sbjct: 487 EWQQQRLPEQKEKLWEQEKM--QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR--EQ 542
Query: 122 ELHLLDFQGKQQNKHVFFFDTKKEVEQ---------FDVATHLQTAPELVDRVFNRPRIE 172
E + + + K +++ +D ++ +E+ +D ++ + +R E
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602
Query: 173 TLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKV 232
+ +E+ + + Q +++ ++ +K + + E+E+K++ +K+ +++ M + Q++
Sbjct: 603 EMMREQEEKMQEQE--EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 233 KVKKE 237
+KE
Sbjct: 661 PEQKE 665
Score = 28.1 bits (61), Expect = 7.7
Identities = 22/106 (20%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Query: 10 KSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYK 69
K +++E + + + + +K ++ + + D K +E +++R++ + +E +
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE-ESMREREKKMREEEEMMR 730
Query: 70 MTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKK 115
K+Q+ ++E +EE+ EQ + M Q+ K E +R+ E K+
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMW-EQEEKMWEQEEKMWEQQRLPEQKE 775
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 40.8 bits (94), Expect = 0.001
Identities = 50/262 (19%), Positives = 112/262 (42%), Gaps = 45/262 (17%)
Query: 1 MAAAFRKAAKSRQREHRERSQPGFRKH----LGLLEKKKDYKLRADDYRK-KQEYLKALR 55
+ A + + K QR R RK L + +K++ + R + +K ++ + LR
Sbjct: 554 VTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLR 613
Query: 56 KKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAE--- 112
++A E+ + + ++K + ++E E++ +L +D+ +++ +
Sbjct: 614 QEAKEREKERILQEHEQIKKKT----VRERLEQIKKTELGAKAFKDIDIEDLEELDPDFI 669
Query: 113 -AKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRI 171
AK++E+L+ E L + K Q K + +F+ K +E+ L+ + RI
Sbjct: 670 MAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIP----------LIKSAYEEQRI 719
Query: 172 ETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDK--- 228
+ + E+Q++ T ++EREK L K + + L D+
Sbjct: 720 KDMD----------------LWEQQEEERITTMQLEREKAL---EHKNRMSRMLEDRDLF 760
Query: 229 TQKVKVKKETVNSPAIYKFQSR 250
++K +++V + +F+ R
Sbjct: 761 VMRLKAARQSVYEEKLKQFEER 782
>gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
Length = 1747
Score = 40.4 bits (93), Expect = 0.001
Identities = 49/234 (20%), Positives = 90/234 (38%), Gaps = 28/234 (11%)
Query: 1 MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALE 60
+A KS ++ H Q GL K+ K+ K L+ +++K
Sbjct: 1484 LAVQVESCGKSNEK-HSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGG 1542
Query: 61 KNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVA------EAK 114
K PD+ + T KL +I E + P Q+K D K + + RV E+
Sbjct: 1543 KQPDKIWIDKT--KLDKLTNISNEAQFSQMPPQVK-----DQKKLYLNRVGFKCTERESI 1595
Query: 115 KIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETL 174
+ +L+S L +Q+NKH F K E+ ++ + P+++
Sbjct: 1596 SLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNM-LEFKLCPDIL------------ 1642
Query: 175 QKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDK 228
+ V + +K ++ Q + +E L +A K +T+KD ++
Sbjct: 1643 -LKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQER 1695
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 39.7 bits (91), Expect = 0.003
Identities = 56/235 (23%), Positives = 103/235 (43%), Gaps = 29/235 (12%)
Query: 31 LEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEE-- 88
L+ K+D +L + +KKQE AL+ EK YK K QD ++KE K +
Sbjct: 2148 LQSKEDLRLMLIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLLKELKSQGN 2207
Query: 89 VTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKH------------ 136
E K + ++E+K + E+ +++L+ + LD ++ + +
Sbjct: 2208 YLLECTKNPSFSEEPWLEIKHLHES-LLQQLQDSVQNLDGHVREHDSYQVCVTDLNTTLD 2266
Query: 137 ----VFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQK-----EKVKGVTNQTG 187
F + K V+Q V LQ EL +R+ + TL+K + VK T+ G
Sbjct: 2267 NFSKEFVSFSDKPVDQIAVEEKLQKLQELENRLSLQD--GTLKKILALAKSVKQNTSSVG 2324
Query: 188 LKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSP 242
++I K+ K C ++ + E +L Q+++ + + K+++ KK P
Sbjct: 2325 -QKIIKDDIKSLQC--KQKDLENRLASAKQEMECCLNSILKSKRSTEKKGKFTLP 2376
Score = 32.3 bits (72), Expect = 0.41
Identities = 26/121 (21%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 4 AFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNP 63
+ ++ +S R R + + + E + ++ DDY + +++LK+ + A N
Sbjct: 6105 SIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNS 6164
Query: 64 DEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSEL 123
E Y + +L+ ++ E +T QL+L+ Q Y + R RLK +
Sbjct: 6165 SEVLYTSAKEELKRFEAFQRQIHERLT--QLELINKQ---YRRLARENRTDTASRLKQMV 6219
Query: 124 H 124
H
Sbjct: 6220 H 6220
Score = 30.0 bits (66), Expect = 2.0
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 6/72 (8%)
Query: 38 KLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLM 97
KL A++ K K L+ LE +P E K + KL+ +H++ + K ++ Q L+
Sbjct: 3124 KLNAEENDK---LYKVLQNMVLELSPKELDEKNCQDKLETSLHVLNQIKSQL---QQPLL 3177
Query: 98 RTQDVKYIEMKR 109
++K+I+ ++
Sbjct: 3178 INLEIKHIQNEK 3189
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 39.7 bits (91), Expect = 0.003
Identities = 56/235 (23%), Positives = 103/235 (43%), Gaps = 29/235 (12%)
Query: 31 LEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEE-- 88
L+ K+D +L + +KKQE AL+ EK YK K QD ++KE K +
Sbjct: 2148 LQSKEDLRLMLIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLLKELKSQGN 2207
Query: 89 VTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKH------------ 136
E K + ++E+K + E+ +++L+ + LD ++ + +
Sbjct: 2208 YLLECTKNPSFSEEPWLEIKHLHES-LLQQLQDSVQNLDGHVREHDSYQVCVTDLNTTLD 2266
Query: 137 ----VFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQK-----EKVKGVTNQTG 187
F + K V+Q V LQ EL +R+ + TL+K + VK T+ G
Sbjct: 2267 NFSKEFVSFSDKPVDQIAVEEKLQKLQELENRLSLQD--GTLKKILALAKSVKQNTSSVG 2324
Query: 188 LKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSP 242
++I K+ K C ++ + E +L Q+++ + + K+++ KK P
Sbjct: 2325 -QKIIKDDIKSLQC--KQKDLENRLASAKQEMECCLNSILKSKRSTEKKGKFTLP 2376
Score = 32.3 bits (72), Expect = 0.41
Identities = 26/121 (21%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 4 AFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNP 63
+ ++ +S R R + + + E + ++ DDY + +++LK+ + A N
Sbjct: 6105 SIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNS 6164
Query: 64 DEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSEL 123
E Y + +L+ ++ E +T QL+L+ Q Y + R RLK +
Sbjct: 6165 SEVLYTSAKEELKRFEAFQRQIHERLT--QLELINKQ---YRRLARENRTDTASRLKQMV 6219
Query: 124 H 124
H
Sbjct: 6220 H 6220
Score = 30.0 bits (66), Expect = 2.0
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 6/72 (8%)
Query: 38 KLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLM 97
KL A++ K K L+ LE +P E K + KL+ +H++ + K ++ Q L+
Sbjct: 3124 KLNAEENDK---LYKVLQNMVLELSPKELDEKNCQDKLETSLHVLNQIKSQL---QQPLL 3177
Query: 98 RTQDVKYIEMKR 109
++K+I+ ++
Sbjct: 3178 INLEIKHIQNEK 3189
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 39.7 bits (91), Expect = 0.003
Identities = 47/226 (20%), Positives = 97/226 (42%), Gaps = 28/226 (12%)
Query: 33 KKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQ---DGVHIIKETKEEV 89
K+K++K + D ++K+ ++ L+++ EKN V++Q +G + E + V
Sbjct: 1063 KEKEHKNQDDLLKEKETLIQQLKEELQEKN------VTLDVQIQHVVEGKRALSELTQGV 1116
Query: 90 TPEQLKLMRTQDVKYIEMKRVAEAKKIER---------LKSELHLLDFQGKQQN-----K 135
T + K+ + + + + + K+E+ LK E +L +FQ Q+ K
Sbjct: 1117 TCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTK 1176
Query: 136 HVFFFDTKKEVEQFDVATHLQTAPELV-----DRVFNRPRIETLQKEKVKGVTNQTGLKR 190
+ + K + E + +LQ L+ + NR E L++E LK
Sbjct: 1177 DLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKA 1236
Query: 191 IAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKK 236
+ +++ Y L +++ KK QK + DK ++K+ +
Sbjct: 1237 DLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1282
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 39.3 bits (90), Expect = 0.003
Identities = 41/232 (17%), Positives = 105/232 (45%), Gaps = 22/232 (9%)
Query: 7 KAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKA-LRKKALEKNPDE 65
K + +R +ER + ++ +++ KL ++ R++QE + LR++ E+
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 66 FYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHL 125
+ +LQ + ++ + E + +L++ ++ K +E +R + K E+ + L
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 126 LDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQ 185
L + +++ + + K+E E E +++ R +E L++E+ +
Sbjct: 579 LKREEERRQQRL-----KREQE------------ERLEQRLKREEVERLEQEE----RRE 617
Query: 186 TGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKE 237
LKR E +++ L + E++ + ++ Q R++ K ++ + + E
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Score = 35.4 bits (80), Expect = 0.048
Identities = 49/254 (19%), Positives = 118/254 (46%), Gaps = 11/254 (4%)
Query: 6 RKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALR-KKALEKNPD 64
R+ + R+R+ RER +RK L +K++ + R++QE K R ++ L++ +
Sbjct: 945 REEREKRRRQERERQ---YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Query: 65 EFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERL-KSEL 123
+ + + + K+E+ E+ +L+R + K +R + ++ E L + E
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 124 HLLDFQGKQQNKHVFFFDTKKEVE-QFDVATHLQTAPELVDRVFNRPRI---ETLQKEKV 179
LL + + + + +KE E Q + L+ PE R + E LQ+E+
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE- 1120
Query: 180 KGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETV 239
+ + + KR +E ++QY + +++E++ + + + R+ +++ + + + +
Sbjct: 1121 EQLLREEREKRRRQELERQYR-EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 240 NSPAIYKFQSRRKR 253
+ + Q +R++
Sbjct: 1180 EEQLLREEQEKRRQ 1193
Score = 30.8 bits (68), Expect = 1.2
Identities = 47/268 (17%), Positives = 114/268 (42%), Gaps = 28/268 (10%)
Query: 1 MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALE 60
+A ++ K + E R+R R+ L ++++++ R ++ R ++E L++ + E
Sbjct: 148 LAEGEEQSEKQERLEQRDRQ----RRDEELWRQRQEWQER-EERRAEEEQLQSCKGHETE 202
Query: 61 KNPDEFYYK----------------MTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKY 104
+ PDE + R + QD V +E KE E + + ++
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 105 IEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDR 164
E +R E ++ E +L + + ++Q + +++ ++ L+ E R
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEE-------EQQQQRLRREQQLRRKQEEERR 315
Query: 165 VFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKD 224
R E ++ + + + L+R +ER++Q Q ER ++ Q+ + R+
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 225 LMDKTQKVKVKKETVNSPAIYKFQSRRK 252
+ + Q+++ +++ + + Q R+
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRR 403
Score = 30.4 bits (67), Expect = 1.5
Identities = 45/211 (21%), Positives = 95/211 (45%), Gaps = 19/211 (9%)
Query: 10 KSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDY-RKKQEYLKALRKKALEKNPDEFYY 68
+ R+++ R FR+ LL++ ++ +LR + RK +E + LR++ E+ +
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714
Query: 69 KMTRVKLQDGVHIIKETKEEVTPEQL-------KLMRTQDVK-YIEMKRVAEAKKIERLK 120
++ R +L+ ++ ++E EQL K++ + ++ E +++ ++ + +
Sbjct: 1715 QLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFR 1774
Query: 121 SELHLLDFQGKQQNKHVFFFDTKKEVEQF-DVATHLQTAPELVDRVFNRPRIETLQKEKV 179
E L + +QQ + +E EQ Q P+ D + R E LQ E+
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY-RWEEEQLQLEEQ 1833
Query: 180 KGVTNQTGLKRIAKERQKQYNCLTQRIEREK 210
+ +R+ +ER +QY Q +EK
Sbjct: 1834 E--------QRLRQERDRQYRAEEQFATQEK 1856
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 38.1 bits (87), Expect = 0.007
Identities = 51/235 (21%), Positives = 104/235 (44%), Gaps = 19/235 (8%)
Query: 6 RKAAKSRQREH-RERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPD 64
+K K R RE +++++ ++ + EK+KD + + +E+LK +
Sbjct: 534 KKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIK 593
Query: 65 EFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELH 124
EF +VKL+DG+ + KE ++ ++ + +D E ++V + + +++K+
Sbjct: 594 EFEDVDPKVKLKDGL-VRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAP 652
Query: 125 LLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTN 184
L K+ +F T V A P L +++F +KEKVK
Sbjct: 653 PLVLPPKELALPLFSPATASRVP----AMLPSLLPVLPEKLFE-------EKEKVKEKEK 701
Query: 185 QTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETV 239
+ K K+++K+ + E+EK+ + + R+ +K + K+K E V
Sbjct: 702 KKDKKEKKKKKEKEKEKKEKEREKEKR------EREKREKEKEKHKHEKIKVEPV 750
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 38.1 bits (87), Expect = 0.007
Identities = 43/218 (19%), Positives = 107/218 (49%), Gaps = 15/218 (6%)
Query: 24 FRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGV---- 79
F+K L KKK ++ ++ RK E+ +++ ++ + R++LQ+ +
Sbjct: 248 FQKEQALWRKKKREEMEEEN-RKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKL 306
Query: 80 HIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFF 139
+ +E++ + +L + + + + K EA+K R + E+ DF+ + K +
Sbjct: 307 EEMLRQREDLEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQ-DFEEQMALKELVL 365
Query: 140 FDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQY 199
K+E E F + A + +R + QK+++K + ++ ++++ +ER++Q+
Sbjct: 366 QAAKEEEENFRKTMLAKFAED------DRIELMNAQKQRMKQLEHRRAVEKLIEERRQQF 419
Query: 200 NCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKE 237
L + +RE + + + Q+ Q + + + +++K+ KE
Sbjct: 420 --LADK-QRELEEWQLQQRRQGFINAIIEEERLKLLKE 454
>gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]
Length = 800
Score = 38.1 bits (87), Expect = 0.007
Identities = 52/233 (22%), Positives = 99/233 (42%), Gaps = 29/233 (12%)
Query: 14 REHRERSQ-PGFRKHLGLLEKKKDYKLRADD---------YRKKQEYLKALRKKALEKNP 63
+ R + Q P FRK + + K + KL+ YRK+Q L+ K A+ K P
Sbjct: 2 KARRNKKQIPSFRKLIKTSKVKLENKLKNKQFKQQSTLKKYRKEQRKLRQAVKDAVSKKP 61
Query: 64 DEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSEL 123
+ + G I +E +EE L +M D++ MK + + ++ L +L
Sbjct: 62 IPLENPKEK---RPGKRIEREEEEEEEALPLDMMDEDDLQL--MKDLGQ--RVSFLTRDL 114
Query: 124 HLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVT 183
+ ++ KH D +++ + LQTAPE + I L + G+
Sbjct: 115 SSSEPVHAKKRKHERIIDKYEKIPR-----TLQTAPE-------KELIHLLPIKDKSGII 162
Query: 184 NQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKK 236
QT K + + + + +R E+ + Q++ + L+++ +K++ KK
Sbjct: 163 PQTREKPVTDSNKDEEDQEEERELEEEIIEDPIQELTIEEHLIERKKKLQEKK 215
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 37.7 bits (86), Expect = 0.010
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 29/222 (13%)
Query: 17 RERSQPGFRKHLGLLEKKKDYKLRAD-DYRKKQEYLKALRKKALEKNPDEFYYKMTRVKL 75
R++ + R+ L ++ K++ +LR R++ E +K +KK +E+ + K + K
Sbjct: 556 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 615
Query: 76 QDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNK 135
+ EE ++ + ++V+ K+ EA+++ L+ E +++ +
Sbjct: 616 E-------RLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQQE--------EEERR 659
Query: 136 HVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKER 195
H KKE EQ L+ A E R E ++E+ + + +R +ER
Sbjct: 660 HQELLQKKKEEEQ----ERLRKAAEAKRLAEQR---EQERREQERREQERREQERREQER 712
Query: 196 QKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKE 237
++Q L ++ R ++ +++Q ++L ++ + ++++KE
Sbjct: 713 REQERQLAEQERRREQ-----ERLQAERELQEREKALRLQKE 749
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 37.7 bits (86), Expect = 0.010
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 29/222 (13%)
Query: 17 RERSQPGFRKHLGLLEKKKDYKLRAD-DYRKKQEYLKALRKKALEKNPDEFYYKMTRVKL 75
R++ + R+ L ++ K++ +LR R++ E +K +KK +E+ + K + K
Sbjct: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Query: 76 QDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNK 135
+ EE ++ + ++V+ K+ EA+++ L+ E +++ +
Sbjct: 612 E-------RLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQQE--------EEERR 655
Query: 136 HVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKER 195
H KKE EQ L+ A E R E ++E+ + + +R +ER
Sbjct: 656 HQELLQKKKEEEQ----ERLRKAAEAKRLAEQR---EQERREQERREQERREQERREQER 708
Query: 196 QKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKE 237
++Q L ++ R ++ +++Q ++L ++ + ++++KE
Sbjct: 709 REQERQLAEQERRREQ-----ERLQAERELQEREKALRLQKE 745
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 36.6 bits (83), Expect = 0.022
Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 14 REHRERSQP---GFRKHLGLLEK--KKDYK--LRADDYRKKQEYLKALRKKALEKNPDEF 66
+EH E Q G K LL++ K+DY L KKQE +KA RK AL+ +PD F
Sbjct: 367 QEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNF 426
Query: 67 YYKMTRVKLQDGVHIIKETKEEVTPEQLK 95
+ + K + I KE ++ +++
Sbjct: 427 QNEEEKKKAEKKFIDIAAAKEVLSDPEMR 455
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 36.6 bits (83), Expect = 0.022
Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 12/238 (5%)
Query: 6 RKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKA-LEKNPD 64
RK R ++ P K +GL++K + R ++ KK + K A +E+ +
Sbjct: 2112 RKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQENE 2171
Query: 65 EFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEA-KKIERLKSEL 123
+ ++ ++K G H + E T K++ + E+K+ +A +K+ K+ L
Sbjct: 2172 KLKAELEKLKAHLG-HQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNL 2230
Query: 124 HLLD----FQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRP--RIETLQKE 177
+L+ Q ++ K + F +++ Q + A +V R++ +ET +
Sbjct: 2231 EILNEKMTVQLEETGKRLQFAESRGP--QLEGADSKSWKSIVVTRMYETKLKELETDIAK 2288
Query: 178 KVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFV-IAQKIQTRKDLMDKTQKVKV 234
K + +T+ L + A ER+++ N + +E++ K+ + + +T + L + Q +++
Sbjct: 2289 KNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLRL 2346
Score = 30.8 bits (68), Expect = 1.2
Identities = 49/232 (21%), Positives = 91/232 (39%), Gaps = 47/232 (20%)
Query: 46 KKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVK-- 103
K Q LK ++KAL + E +MT + + + + + +Q+ T+++K
Sbjct: 1731 KSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQ 1790
Query: 104 -------YIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFD------ 150
+++K + K +L D + Q K + +E E+ D
Sbjct: 1791 VEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDEL 1850
Query: 151 ------VATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTG--LKRIAKERQKQYNCL 202
+ + LQ P L D + IE LQ+ KVK + NQ ++ + + K+ N
Sbjct: 1851 KRQIKRLTSGLQGKP-LTDN--KQSLIEELQR-KVKKLENQLEGKVEEVDLKPMKEKNAK 1906
Query: 203 TQRI--------------------EREKKLFVIAQKIQTRKDLMDKTQKVKV 234
+ I E+E ++F + +++ T KDL K K K+
Sbjct: 1907 EELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKL 1958
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 36.2 bits (82), Expect = 0.028
Identities = 37/247 (14%), Positives = 119/247 (48%), Gaps = 5/247 (2%)
Query: 10 KSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYK 69
K R++E + + + R+ E++ + + R+++E ++ KK + +E ++
Sbjct: 391 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ--EEKIHE 448
Query: 70 MTRVKLQDGVHIIKET--KEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLD 127
+++ ++ +E +EE EQ ++ R ++ + + K + +K+ R + ++H +
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 128 FQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTG 187
+ ++Q + ++ + K ++ + + E + + + Q+EK++
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Query: 188 LKRIAKERQKQYNCLTQRI-EREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYK 246
+ +E++++ ++I E+E+K++ +KI+ ++++M + ++ ++E K
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
Query: 247 FQSRRKR 253
Q + ++
Sbjct: 629 MQEQEEK 635
Score = 34.7 bits (78), Expect = 0.082
Identities = 43/236 (18%), Positives = 113/236 (47%), Gaps = 29/236 (12%)
Query: 5 FRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPD 64
+ K K R+ E + Q R+ +++++ K+R + R++QE +++ + + +
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEE--KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 65 EFYYKMTRV-KLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSEL 123
+ + ++ + ++ +H ++ +EE ++ + M Q+ K + E ++I R K ++
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK------IREQEEIWRQKEKM 484
Query: 124 HLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVT 183
H + KQ+ K ++E + D ++ E + R Q+EK++
Sbjct: 485 HEQEKIRKQEEKV-----WRQEEKMHDQEEKIREQEEKMWR----------QEEKIR--- 526
Query: 184 NQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETV 239
Q R +E+ ++ + Q E+E+K+ +K+Q ++ + + +K++ ++E +
Sbjct: 527 EQEEKIREQEEKIREQEEMMQ--EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Score = 30.4 bits (67), Expect = 1.5
Identities = 40/240 (16%), Positives = 116/240 (48%), Gaps = 18/240 (7%)
Query: 10 KSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNP-----D 64
+ ++ + RE+ + R+ + EK++ + + + +K+E ++ L + EK +
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 65 EFYYKMTRVKLQDGVHIIKET---KEEVTPEQLKLMRTQD-VKYIEMKRVAEAKKIERLK 120
E ++ +++ Q+ +E +E+ ++ K+ R ++ ++ E K + KK+ R +
Sbjct: 384 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443
Query: 121 SELH---LLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKE 177
++H + + K+Q + + +K EQ ++ + E +++ + Q+E
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ-EKIRKQEEKVWRQEE 502
Query: 178 KVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKE 237
K+ ++I ++ +K + + E+E+K+ +KI+ ++++M + ++ ++E
Sbjct: 503 KMHDQE-----EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
Score = 28.1 bits (61), Expect = 7.7
Identities = 33/192 (17%), Positives = 90/192 (46%), Gaps = 35/192 (18%)
Query: 74 KLQDGVHIIKETKEEVTPEQLKLMRTQDV-----------------KYIEMKRVAE---- 112
K+Q+ I+E +E++ ++ K+ R +++ K +M+R+ E
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 113 -AKKIERLKSELH----LLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFN 167
+KI L+ ++H + + + K+Q + K++ ++ + + E +++
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 168 RPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMD 227
+ + Q+EK+ ++ R ++RQ+Q + + R+++ ++I +K+ M
Sbjct: 435 QEKKMWRQEEKI----HEQEKIREEEKRQEQ-----EEMWRQEEKIREQEEIWRQKEKMH 485
Query: 228 KTQKVKVKKETV 239
+ +K++ ++E V
Sbjct: 486 EQEKIRKQEEKV 497
>gi|33469933 phospholipase C beta 4 isoform a [Homo sapiens]
Length = 1194
Score = 36.2 bits (82), Expect = 0.028
Identities = 57/236 (24%), Positives = 108/236 (45%), Gaps = 29/236 (12%)
Query: 31 LEKKKDYKL----RADDYRKKQEYLKALRKK-----ALEKNPDEFYYKMTRVKLQDGVHI 81
+E KK +L R +D ++ + YLK L+K+ +L+K + + M ++ I
Sbjct: 905 VEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKI 964
Query: 82 IKE-TKEEVTPEQL--KLMRTQ-DVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHV 137
+ + KE+ T E++ K M+ + +EMK+ E KI+ L S+ K + K +
Sbjct: 965 VAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEI-KIQTLTSD-------HKSKVKEI 1016
Query: 138 FFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQK 197
TK+ E + TH E+ D ++ + E L+K + QT +++ +R+
Sbjct: 1017 VAQHTKEWSEM--INTHSAEEQEIRDLHLSQ-QCELLKKLLINAHEQQTQQLKLSHDRES 1073
Query: 198 QYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRKR 253
+ R + K ++ I K + +K ++ + +E +NS KF RKR
Sbjct: 1074 K----EMRAHQAKISMENSKAISQDKSIKNKAERERRVRE-LNSSNTKKFLEERKR 1124
>gi|33469939 phospholipase C beta 4 isoform b [Homo sapiens]
Length = 1175
Score = 36.2 bits (82), Expect = 0.028
Identities = 57/236 (24%), Positives = 108/236 (45%), Gaps = 29/236 (12%)
Query: 31 LEKKKDYKL----RADDYRKKQEYLKALRKK-----ALEKNPDEFYYKMTRVKLQDGVHI 81
+E KK +L R +D ++ + YLK L+K+ +L+K + + M ++ I
Sbjct: 905 VEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKI 964
Query: 82 IKE-TKEEVTPEQL--KLMRTQ-DVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHV 137
+ + KE+ T E++ K M+ + +EMK+ E KI+ L S+ K + K +
Sbjct: 965 VAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEI-KIQTLTSD-------HKSKVKEI 1016
Query: 138 FFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQK 197
TK+ E + TH E+ D ++ + E L+K + QT +++ +R+
Sbjct: 1017 VAQHTKEWSEM--INTHSAEEQEIRDLHLSQ-QCELLKKLLINAHEQQTQQLKLSHDRES 1073
Query: 198 QYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRKR 253
+ R + K ++ I K + +K ++ + +E +NS KF RKR
Sbjct: 1074 K----EMRAHQAKISMENSKAISQDKSIKNKAERERRVRE-LNSSNTKKFLEERKR 1124
>gi|13027602 DDRGK domain containing 1 [Homo sapiens]
Length = 314
Score = 36.2 bits (82), Expect = 0.028
Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 12/122 (9%)
Query: 7 KAAKSRQREHRERSQPGFRKHLGLLE---KKKDYKLRADDYRKKQEYLKALRKKALEKNP 63
K A+ QRE E + ++ E KK++ +LR ++ +K++E KA ++A ++
Sbjct: 128 KQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHE 187
Query: 64 DEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSEL 123
+ K V ++GV E +T EQ + T+ + YI+ +V +E L S++
Sbjct: 188 EYLKLKEAFVVEEEGV------GETMTEEQSQSFLTEFINYIKQSKVV---LLEDLASQV 238
Query: 124 HL 125
L
Sbjct: 239 GL 240
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 36.2 bits (82), Expect = 0.028
Identities = 55/277 (19%), Positives = 120/277 (43%), Gaps = 48/277 (17%)
Query: 4 AFRKAAKSRQ---REHRERSQPGFRKHLGL---LEKKKDYKLRADDYRKKQEYLKALRKK 57
A RKA K ++ R+ RE + ++K L L LEK+++ + + ++ R+K + K+
Sbjct: 393 AERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQ 452
Query: 58 ALEKNPDEFYYKMTRVKL-------QDGVHIIKETKEEVTPEQLKLM--------RTQDV 102
LE+ + ++ R +L Q+ + + K+ + E L R QDV
Sbjct: 453 ELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDV 512
Query: 103 KYIEMKRVAEAKKIERLKSELHLLDFQGKQQ------NKHVFFFDTKKEVEQFDVATHLQ 156
+ + + E + +++ + +L +++ + QQ NK ++ K+ + +
Sbjct: 513 RLKKQTQKTELEVLDK-QCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFS 571
Query: 157 TAP---------------ELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNC 201
P EL R+ + +++ L+KE ++ KE ++ YN
Sbjct: 572 NTPDSGVSLLHKKSLEKEELCQRL--KEQLDALEKETASKLSEMDSFNNQLKELRETYN- 628
Query: 202 LTQRIEREKKLFVIAQKI-QTRKDLMDKTQKVKVKKE 237
TQ++ E+ + K+ + + ++ QK K++ E
Sbjct: 629 -TQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDE 664
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 35.8 bits (81), Expect = 0.037
Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 37/248 (14%)
Query: 17 RERSQPGFRKHLGLLEK---KKDYKLRADDY---RKKQEYLKALRKKALEKNPDEFYYKM 70
+E S ++H L KKD +L+ + +KK+E LK + L+K +
Sbjct: 671 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKM--ESQLKKAHEAALEAR 728
Query: 71 TRVKLQDGV-HIIKET---KEEVTPEQLKLMRTQDV-KYIEMKRVAEAKKIERLKSELHL 125
++ D + H+ +E K+E + Q ++ R ++ K +E ++ + KKI L+ ++
Sbjct: 729 ASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV-- 786
Query: 126 LDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNR------------PRIET 173
K QNK V K++VE+ A L+ A D + + RIE
Sbjct: 787 -----KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEE 841
Query: 174 LQKEKVKGVTNQTGLKR---IAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQ 230
L++ + V Q +R +A+E + N Q E + + Q++++ K + TQ
Sbjct: 842 LEEALRESV--QITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQ 899
Query: 231 KVKVKKET 238
+ +KET
Sbjct: 900 QSLAEKET 907
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 35.8 bits (81), Expect = 0.037
Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 37/248 (14%)
Query: 17 RERSQPGFRKHLGLLEK---KKDYKLRADDY---RKKQEYLKALRKKALEKNPDEFYYKM 70
+E S ++H L KKD +L+ + +KK+E LK + L+K +
Sbjct: 643 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKM--ESQLKKAHEAALEAR 700
Query: 71 TRVKLQDGV-HIIKET---KEEVTPEQLKLMRTQDV-KYIEMKRVAEAKKIERLKSELHL 125
++ D + H+ +E K+E + Q ++ R ++ K +E ++ + KKI L+ ++
Sbjct: 701 ASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV-- 758
Query: 126 LDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNR------------PRIET 173
K QNK V K++VE+ A L+ A D + + RIE
Sbjct: 759 -----KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEE 813
Query: 174 LQKEKVKGVTNQTGLKR---IAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQ 230
L++ + V Q +R +A+E + N Q E + + Q++++ K + TQ
Sbjct: 814 LEEALRESV--QITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQ 871
Query: 231 KVKVKKET 238
+ +KET
Sbjct: 872 QSLAEKET 879
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 35.8 bits (81), Expect = 0.037
Identities = 47/220 (21%), Positives = 87/220 (39%), Gaps = 20/220 (9%)
Query: 30 LLEKKKDYKLRADDYRK----KQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKET 85
LL+K++DY + + + K+ L +K L+ + + L +H+
Sbjct: 311 LLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHR-IHVELSE 369
Query: 86 KEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTK-- 143
K E T + + + + KY +K + + +R + E H L Q + H +T+
Sbjct: 370 KGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQ 429
Query: 144 --------KEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLK-RIAKE 194
KE Q + ++ D R+E KEK VTN T L+ ++ K
Sbjct: 430 LGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEK---VTNSTELQHQLDKT 486
Query: 195 RQKQYNCLTQRIEREKKLFVIAQKI-QTRKDLMDKTQKVK 233
+Q+ + KL + Q + + DK QK++
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQ 526
Score = 31.6 bits (70), Expect = 0.69
Identities = 51/240 (21%), Positives = 105/240 (43%), Gaps = 29/240 (12%)
Query: 25 RKHLGLLEKKKDYKLRADDYRKKQ--EYLKALRKKALEKNP--DEFYYKMTRVKLQDGVH 80
++++ LLEK+++ D Y K Q E A+ + EKN E ++T KL++
Sbjct: 536 KENISLLEKERE-----DLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTE-KLKNQSE 589
Query: 81 IIKETKE----EVTPEQLKLMRTQD-VKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNK 135
K+ +E +V ++ L QD V +E ++ K ++ LD Q K + +
Sbjct: 590 SHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTE 649
Query: 136 HVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKER 195
+ + K ++ D+ HL TA + +++++ +T Q + AK +
Sbjct: 650 LLLSAEAAKTAQRADLQNHLDTAQNALQD----------KQQELNKITTQLD-QVTAKLQ 698
Query: 196 QKQYNCL---TQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRK 252
KQ +C + E ++K + QK + + + K + ++ + A+ Q +R+
Sbjct: 699 DKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQ 758
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 35.4 bits (80), Expect = 0.048
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 19/200 (9%)
Query: 12 RQREHRERSQPGFRK-HLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKM 70
R+RE R+R + RK G EKK + RKK+E + R++ E E K
Sbjct: 64 REREKRKREREKERKRERGKKEKKGE--------RKKEERERKKRRREKENKEGEEKEKR 115
Query: 71 TRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQG 130
+ + ++ KE KE E+ K ++ + + +R E ++ ER K E + +
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG-EK 174
Query: 131 KQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKR 190
+++ K + KK + E +R R + E +KE+ K QT +
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK--DRQTNWRE 232
Query: 191 IAKERQKQYNCLTQRIEREK 210
KER K+ +R ER+K
Sbjct: 233 --KERGKR-----ERKERKK 245
Score = 31.2 bits (69), Expect = 0.91
Identities = 45/193 (23%), Positives = 88/193 (45%), Gaps = 19/193 (9%)
Query: 6 RKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDE 65
R+ K R+RE ++ + G RK E+++ K R + K+ E + +KK ++
Sbjct: 71 REREKERKRERGKKEKKGERKK----EERERKKRRREKENKEGEEKEKRKKKEKKERGRT 126
Query: 66 FYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHL 125
R + ++ ++ +E E+ K ++ K E K+V E K+ ER + E
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE-KEEERKEKERK- 184
Query: 126 LDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPR-IETLQKEKVKGVTN 184
+ + +++N+ + KKE E+ + + + +R R + +T +EK +G
Sbjct: 185 -ERKKRERNRK----ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG--- 236
Query: 185 QTGLKRIAKERQK 197
KR KER+K
Sbjct: 237 ----KRERKERKK 245
Score = 30.8 bits (68), Expect = 1.2
Identities = 53/241 (21%), Positives = 107/241 (44%), Gaps = 37/241 (15%)
Query: 20 SQPGFRKHLGL----LEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKL 75
+QPG++ + +E +K+ K + RKK+ + RK+ EK K
Sbjct: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKER----------KR 79
Query: 76 QDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAK-KIERLKSELHLLDFQGKQQN 134
+ G K +++ E+ K R ++ K E K + K K ER ++ + + K++
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
Query: 135 KHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKE-KVKGVTNQTGLKRIAK 193
K + +KE E+ + +R R R E ++E K G + ++ K
Sbjct: 140 KR----EERKERER-----------KKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
Query: 194 ERQK-QYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRK 252
ER+K + N ++ ERE+K ++ + +K+ K ++ K +++ + K + +R+
Sbjct: 185 ERKKRERNRKERKKERERK-----ERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239
Query: 253 R 253
R
Sbjct: 240 R 240
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 35.4 bits (80), Expect = 0.048
Identities = 51/229 (22%), Positives = 104/229 (45%), Gaps = 18/229 (7%)
Query: 30 LLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEV 89
L +K++ + + + D K +E L + K EK+ E + KL++ + I + +
Sbjct: 835 LHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN 894
Query: 90 TPEQLKL-----MRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVF--FFDT 142
+ + K+ ++ +DV+ +++K + L+ + + + +Q + +
Sbjct: 895 SSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 954
Query: 143 KKEVEQ--FDVATHLQTA----PELVDRVFNRPRIETLQK-EKVKGVTNQTGL--KRIAK 193
KKE+E+ D+ ++T+ EL R + R ET K E++ +T L + K
Sbjct: 955 KKELERKLSDLEKKMETSHNQCQELKAR-YERATSETKTKHEEILQNLQKTLLDTEDKLK 1013
Query: 194 ERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMD-KTQKVKVKKETVNS 241
+++ + L Q +E +K A+ QT +D M Q K K ET+ S
Sbjct: 1014 GAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLAS 1062
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 35.4 bits (80), Expect = 0.048
Identities = 51/229 (22%), Positives = 104/229 (45%), Gaps = 18/229 (7%)
Query: 30 LLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEV 89
L +K++ + + + D K +E L + K EK+ E + KL++ + I + +
Sbjct: 870 LHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN 929
Query: 90 TPEQLKL-----MRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVF--FFDT 142
+ + K+ ++ +DV+ +++K + L+ + + + +Q + +
Sbjct: 930 SSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 989
Query: 143 KKEVEQ--FDVATHLQTA----PELVDRVFNRPRIETLQK-EKVKGVTNQTGL--KRIAK 193
KKE+E+ D+ ++T+ EL R + R ET K E++ +T L + K
Sbjct: 990 KKELERKLSDLEKKMETSHNQCQELKAR-YERATSETKTKHEEILQNLQKTLLDTEDKLK 1048
Query: 194 ERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMD-KTQKVKVKKETVNS 241
+++ + L Q +E +K A+ QT +D M Q K K ET+ S
Sbjct: 1049 GAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLAS 1097
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 35.4 bits (80), Expect = 0.048
Identities = 42/180 (23%), Positives = 74/180 (41%), Gaps = 11/180 (6%)
Query: 7 KAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRK-----KALEK 61
K +K +QR + S K K++ + + E K L K K +
Sbjct: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSE 368
Query: 62 NPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKS 121
P E K RVK + + E ++ + + K + + +E K+ E K+I++ +
Sbjct: 369 KPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERK 428
Query: 122 ELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKG 181
EL +G+++ K D KKE ++ D L+ + + F +TL K KV G
Sbjct: 429 ELK--KDEGRKEEKK----DAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPG 482
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 35.4 bits (80), Expect = 0.048
Identities = 48/211 (22%), Positives = 90/211 (42%), Gaps = 18/211 (8%)
Query: 43 DYRKKQEYLKALRKKALEKNPDEF---YYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRT 99
++++ + LKALR + NP+ F + L+D + + KE L+ MR+
Sbjct: 546 EFQEHEHALKALR--LINNNPEIFGPLKRPIVEFSLEDRRKL--KMKELRIQRSLQKMRS 601
Query: 100 QDVKYIEMKRVAEAKKIERLKSELHLLDFQGK---QQNKHVFF-----FDTKKEVEQFDV 151
+ K E K ++ K+ H + Q K +Q + F TK EVEQ ++
Sbjct: 602 KPATGEPQKGQPEPAKDQQQKAAQHHTEEQSKVPPEQKRKAGSTSWTGFQTKAEVEQVEL 661
Query: 152 ATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKK 211
+ L P+I K KVK V + +I + +Q++ ++++ R+K
Sbjct: 662 PDGKKRRKVLALPSHRGPKIRLRDKGKVKPVHPKKPKPQINQWKQEKQQLSSEQVSRKK- 720
Query: 212 LFVIAQKIQTRKDLMDKTQKVKVKKETVNSP 242
K +TR + + + K K+ + +P
Sbjct: 721 --AKGNKTETRFNQLVEQYKQKLLGPSKGAP 749
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 35.4 bits (80), Expect = 0.048
Identities = 47/242 (19%), Positives = 96/242 (39%), Gaps = 32/242 (13%)
Query: 13 QREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTR 72
Q E +++ + R+ L + E+K++ +L R +QEY + KK EK ++ R
Sbjct: 742 QIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKR-EKEEEQ------R 794
Query: 73 VKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQ 132
+K ++ + + +E ++E E K+ E +K D +
Sbjct: 795 LKNEEHIRLAEERQKEA----------------ERKKKEEEEKYNLQLQHYCERDNLIGE 838
Query: 133 QNKHVFFFDTKKEVEQFDVATHLQTAP---ELVDRVFNRPRIETLQKEKVKGVTNQTGLK 189
+ KH+ Q +A+ LQ P ++ + + Q V NQ
Sbjct: 839 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQ---- 894
Query: 190 RIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQS 249
+ +++ N + + E K+L +++Q R MD ++ ++K+ N I+
Sbjct: 895 --LRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMAR 952
Query: 250 RR 251
R
Sbjct: 953 HR 954
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,567,040
Number of Sequences: 37866
Number of extensions: 367024
Number of successful extensions: 2343
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 202
Number of HSP's that attempted gapping in prelim test: 2098
Number of HSP's gapped (non-prelim): 398
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.