Guide to the Human Genome
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Search of human proteins with 156415990

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156415990 Y box binding protein 2 [Homo sapiens]
         (364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156415990 Y box binding protein 2 [Homo sapiens]                   755   0.0  
gi|224586882 cold shock domain protein A isoform a [Homo sapiens]     238   6e-63
gi|34098946 nuclease sensitive element binding protein 1 [Homo s...   233   2e-61
gi|224586884 cold shock domain protein A isoform b [Homo sapiens]     218   7e-57
gi|51972214 lin-28 homolog B [Homo sapiens]                            69   7e-12
gi|13375938 lin-28 homolog [Homo sapiens]                              68   1e-11
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    60   2e-09
gi|150170670 piccolo isoform 2 [Homo sapiens]                          57   2e-08
gi|150378539 piccolo isoform 1 [Homo sapiens]                          57   2e-08
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       55   1e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     55   1e-07
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       54   3e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    53   4e-07
gi|169163728 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|169163708 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|169163019 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|188536004 zinc finger protein 469 [Homo sapiens]                    50   3e-06
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    49   5e-06
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    49   5e-06
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    49   5e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    49   5e-06
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       49   7e-06
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    49   7e-06
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    49   7e-06
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    49   7e-06
gi|38787970 tensin like C1 domain containing phosphatase isoform...    48   1e-05
gi|38787957 tensin like C1 domain containing phosphatase isoform...    48   1e-05
gi|38787941 tensin like C1 domain containing phosphatase isoform...    48   1e-05
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    48   1e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    48   2e-05

>gi|156415990 Y box binding protein 2 [Homo sapiens]
          Length = 364

 Score =  755 bits (1950), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 1   MSEVEAAAGATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSA 60
           MSEVEAAAGATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSA
Sbjct: 1   MSEVEAAAGATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSA 60

Query: 61  PGSRTPGNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVF 120
           PGSRTPGNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVF
Sbjct: 61  PGSRTPGNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVF 120

Query: 121 VHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKS 180
           VHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKS
Sbjct: 121 VHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKS 180

Query: 181 RRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRP 240
           RRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRP
Sbjct: 181 RRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRP 240

Query: 241 PNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG 300
           PNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG
Sbjct: 241 PNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG 300

Query: 301 ETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPTT 360
           ETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPTT
Sbjct: 301 ETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPTT 360

Query: 361 TILE 364
           TILE
Sbjct: 361 TILE 364


>gi|224586882 cold shock domain protein A isoform a [Homo sapiens]
          Length = 372

 Score =  238 bits (607), Expect = 6e-63
 Identities = 166/373 (44%), Positives = 196/373 (52%), Gaps = 29/373 (7%)

Query: 7   AAGATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGS-RT 65
           A  AT     T+P       A     PA  P+   G+G    AA  PAA     PG    
Sbjct: 4   AGEATTTTTTTLPQAPTEAAAAAPQDPA--PKSPVGSGAPQAAAPAPAAHVAGNPGGDAA 61

Query: 66  PGNPATAVSGTPAPPARSQ-ADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQT 124
           P    TA + + A  A S+ A+K VLA +VLGTVKWFNVRNGYGFINRNDTKEDVFVHQT
Sbjct: 62  PAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQT 121

Query: 125 AIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFI 184
           AIK+NNPRK+LRSVGDGETVEFDVVEGEKGAEA NVTGP GVPV+GSRYA +RR+ RR  
Sbjct: 122 AIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGY 181

Query: 185 PRPPSVAPPPMVAEIPSAGTGPGSKG----------ERAEDSGQRP------RRWCPPPF 228
                  P     E    G+G  S+G            A +  +RP      R+   PP+
Sbjct: 182 YGRRRGPPRNYAGEEEEEGSG-SSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPY 240

Query: 229 FYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPR 288
              + F R  R       I+  +  E K+  P EG Q QG      P +RPRYR    PR
Sbjct: 241 HVGQTFDRRSRVLPHPNRIQAGEIGEMKDGVP-EGAQLQGPVH-RNPTYRPRYRSRGPPR 298

Query: 289 PRQQPTTEGGDGETKPSQGPADG-SRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAP 347
           PR  P    G+ E K +Q    G ++P  +R   RPY  RRR   P P  AP      A 
Sbjct: 299 PRPAPAV--GEAEDKENQQATSGPNQPSVRRGYRRPYNYRRR---PRPPNAPSQDGKEAK 353

Query: 348 ETSAPVNSGDPTT 360
              AP  +  P T
Sbjct: 354 AGEAPTENPAPPT 366


>gi|34098946 nuclease sensitive element binding protein 1 [Homo
           sapiens]
          Length = 324

 Score =  233 bits (595), Expect = 2e-61
 Identities = 156/355 (43%), Positives = 193/355 (54%), Gaps = 58/355 (16%)

Query: 11  TAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPA 70
           T  P A  PA  A   A   P   G    G G+GG GG  S   AG              
Sbjct: 7   TQQPPAAPPAAPALSAADTKPGTTGS---GAGSGGPGGLTSAAPAG-------------- 49

Query: 71  TAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNN 130
                          DK V+A +VLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIK+NN
Sbjct: 50  --------------GDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNN 95

Query: 131 PRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSV 190
           PRK+LRSVGDGETVEFDVVEGEKGAEA NVTGPGGVPV+GS+YA +R   RR+   P   
Sbjct: 96  PRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRRY---PRRR 152

Query: 191 APPPMVAE-IPSAGTGPGSKGERAEDSGQ----RP-RRWCPPPFFYRRRFVRGPR---PP 241
            PP    +   ++ +G  ++G  +   GQ    RP RR   PP++ RR + R P+   PP
Sbjct: 153 GPPRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPP 212

Query: 242 NQQQPIEGTDRVEPKETA-PLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG 300
            Q + +EG D     E   P+  +  +G        +RPR+R   R  PRQ+   E G+ 
Sbjct: 213 VQGEVMEGADNQGAGEQGRPVRQNMYRG--------YRPRFR---RGPPRQRQPREDGNE 261

Query: 301 ETKPSQG-PADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPR--QPAAPETSAP 352
           E K +QG    G +P  +R R    ++RRR + P PQ     +   P A  +SAP
Sbjct: 262 EDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDGKETKAADPPAENSSAP 316


>gi|224586884 cold shock domain protein A isoform b [Homo sapiens]
          Length = 303

 Score =  218 bits (555), Expect = 7e-57
 Identities = 148/319 (46%), Positives = 171/319 (53%), Gaps = 30/319 (9%)

Query: 7   AAGATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGS-RT 65
           A  AT     T+P       A     PA  P+   G+G    AA  PAA     PG    
Sbjct: 4   AGEATTTTTTTLPQAPTEAAAAAPQDPA--PKSPVGSGAPQAAAPAPAAHVAGNPGGDAA 61

Query: 66  PGNPATAVSGTPAPPARSQ-ADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQT 124
           P    TA + + A  A S+ A+K VLA +VLGTVKWFNVRNGYGFINRNDTKEDVFVHQT
Sbjct: 62  PAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQT 121

Query: 125 AIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRR-F 183
           AIK+NNPRK+LRSVGDGETVEFDVVEGEKGAEA NVTGP GVPV+GSRYA +RR+ RR +
Sbjct: 122 AIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGY 181

Query: 184 IPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQ 243
             R     PP    EI   G       E A+  G   R     P +  R   RGP  P  
Sbjct: 182 YGR--RRGPPRNAGEI---GEMKDGVPEGAQLQGPVHRN----PTYRPRYRSRGPPRP-- 230

Query: 244 QQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPF----RPRPRQQPTTEGGD 299
            +P       E KE        QQ       P  R  YRRP+    RPRP   P+ +G  
Sbjct: 231 -RPAPAVGEAEDKE-------NQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDG-- 280

Query: 300 GETKPSQGPADGSRPEPQR 318
            E K  + P +   P  Q+
Sbjct: 281 KEAKAGEAPTENPAPPTQQ 299


>gi|51972214 lin-28 homolog B [Homo sapiens]
          Length = 250

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 50/140 (35%), Positives = 65/140 (46%), Gaps = 23/140 (16%)

Query: 54  AAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFI--- 110
           A G  S  G   PG         P P     A++    ++  G  KWFNVR G+GFI   
Sbjct: 2   AEGGASKGGGEEPGK-------LPEP-----AEEESQVLRGTGHCKWFNVRMGFGFISMI 49

Query: 111 NRN----DTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGV 166
           NR     D   DVFVHQ+ +         RS+ +GE VEF   +  KG E+  VTGPGG 
Sbjct: 50  NREGSPLDIPVDVFVHQSKLFMEG----FRSLKEGEPVEFTFKKSSKGLESIRVTGPGGS 105

Query: 167 PVKGSRYAPNRRKSRRFIPR 186
           P  GS   P  +  ++  P+
Sbjct: 106 PCLGSERRPKGKTLQKRKPK 125


>gi|13375938 lin-28 homolog [Homo sapiens]
          Length = 209

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 44/113 (38%), Positives = 59/113 (52%), Gaps = 13/113 (11%)

Query: 77  PAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRN-------DTKEDVFVHQTAIKRN 129
           P   AR+ AD+P L +   G  KWFNVR G+GF++         D   DVFVHQ+ +   
Sbjct: 25  PEDAARA-ADEPQL-LHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHME 82

Query: 130 NPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRR 182
                 RS+ +GE VEF   +  KG E+  VTGPGGV   GS   P  +  ++
Sbjct: 83  G----FRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQK 131


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 22/199 (11%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPPS---VAPPPMVAEIPSAGTGPGSKGERAEDSGQR 219
           P G P  G    P  +  +   PR P      PPP     P     P  K +     G +
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188

Query: 220 PRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRP 279
             +  PPP        +GP P   +     +   +P+   P  G+Q QG    PPP  +P
Sbjct: 189 KPQGPPPP-----GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP---PPPPGKP 240

Query: 280 RYRRPFRPRPRQQPTTEGGDGETKPSQGPADG------SRPEPQRPRNRPYFQRRRQQAP 333
           +   P      Q P   G     KP   PA G      +R  P +P+  P  +    Q P
Sbjct: 241 QGPPPQGGNKPQGPPPPG-----KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 295

Query: 334 GPQQAPGPRQPAAPETSAP 352
            P     P+QP AP    P
Sbjct: 296 PPPAGGNPQQPQAPPAGQP 314



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 53/194 (27%), Positives = 69/194 (35%), Gaps = 40/194 (20%)

Query: 185 PRPPSV--APPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYR------RRFVR 236
           P PP     PPP   +  S  + PG         G +P+   PPP   +          +
Sbjct: 71  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130

Query: 237 GPRPPNQQQ--PIEGTDRVEPKE-------TAPLEGHQQQGDERVPPPRFRPRYRRPFRP 287
           GP PP + Q  P +G     P+          P  G+Q QG    PPP  +P        
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---PPPPGKP-------- 179

Query: 288 RPRQQPTTEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPR---QP 344
              Q P  +GG    K  QGP    +P+   P+      R  Q  PG  Q P P+   QP
Sbjct: 180 ---QGPPPQGG----KKPQGPPPPGKPQGPPPQGDK--SRSSQSPPGKPQGPPPQGGNQP 230

Query: 345 AAPETSAPVNSGDP 358
             P        G P
Sbjct: 231 QGPPPPPGKPQGPP 244



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 10/121 (8%)

Query: 236 RGPRPPNQQQPIEGTDRV--EPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQP 293
           +GP P    +P +G      +P+   P  G++ QG    PPP  +P+   P   + R  P
Sbjct: 37  QGPSPQGGNKP-QGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQGDKSRS-P 90

Query: 294 TTEGGDGETKPSQG--PADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSA 351
            +  G  +  P QG     G  P P +P+  P     R Q P P   P    P   ++ +
Sbjct: 91  RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150

Query: 352 P 352
           P
Sbjct: 151 P 151



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 23/109 (21%)

Query: 255 PKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADG--S 312
           P+  +P  G++ QG    PPP  +P           Q P  +GG+   KP   P  G   
Sbjct: 36  PQGPSPQGGNKPQGP---PPPPGKP-----------QGPPPQGGN---KPQGPPPPGKPQ 78

Query: 313 RPEPQRPRNR-PYFQRRRQQAPGPQ---QAPGPRQPAAPETSAPVNSGD 357
            P PQ  ++R P     + Q P PQ   Q  GP  P       P   G+
Sbjct: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 17/56 (30%), Positives = 21/56 (37%), Gaps = 1/56 (1%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKP 88
           P G P +GG       +  G   G P   G+   G P  A  G P  P    A +P
Sbjct: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA-GGNPQQPQAPPAGQP 314



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 17/58 (29%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKP 88
           P P G+PQ     GG    ++    G P  P  +   NP       P PPA     +P
Sbjct: 254 PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ-----GPPPPAGGNPQQP 306



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 18/67 (26%), Positives = 22/67 (32%), Gaps = 11/67 (16%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNP-----------ATAVSGTPAPPA 81
           P G P +GG    G      P    P    SR+P +P                G P PP 
Sbjct: 118 PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 177

Query: 82  RSQADKP 88
           + Q   P
Sbjct: 178 KPQGPPP 184



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 18/56 (32%), Positives = 22/56 (39%), Gaps = 7/56 (12%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKP 88
           P G PQ+ G    G      PA G P  P +   G P     G P PP   +  +P
Sbjct: 281 PQGPPQQEGNNPQG---PPPPAGGNPQQPQAPPAGQP----QGPPRPPQGGRPSRP 329



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 7/63 (11%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNP-------ATAVSGTPAPPARSQA 85
           P G P +GG    G     G   G P   G++  G P         A  G+ +  ARS  
Sbjct: 219 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPP 278

Query: 86  DKP 88
            KP
Sbjct: 279 GKP 281


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 19/187 (10%)

Query: 185 PRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQ 244
           P P ++A PP V + P+   GP     +   +   P+     P         GP     Q
Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT---PKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 245 QPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFR-PRYRRPFRPRPRQQPTTEGGD---- 299
           QP  G  ++  ++  P +   QQ     PP +   P    P +P P + P  + G     
Sbjct: 443 QP--GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500

Query: 300 ----GETKPSQGPADGSRPEPQRPRN-RPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVN 354
               G TKP       ++P PQ+P + +P  Q+     P  QQ P P +P+A +++ PV+
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ-PSPAKPSAQQSTKPVS 559

Query: 355 ---SGDP 358
              SG P
Sbjct: 560 QTGSGKP 566



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/174 (24%), Positives = 64/174 (36%), Gaps = 24/174 (13%)

Query: 188 PSVAPPPMVAEIPSAGTG--PGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQ 245
           P+ AP P    +   G G  P  +    + S Q+     PP        + GP  P  QQ
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ------LPGPAKPPPQQ 483

Query: 246 PIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPS 305
           P  G  +  P++    +   QQ     PPP+       P +P P+Q  +T+      +P 
Sbjct: 484 P--GPAKPPPQQPGSAKPPSQQPGSTKPPPQ----QPGPAKPSPQQPGSTK--PPSQQPG 535

Query: 306 QGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPT 359
                  +P P +P          QQ+  P    G  +P  P T +P     P+
Sbjct: 536 SAKPSAQQPSPAKP--------SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 15/124 (12%)

Query: 238 PRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEG 297
           P  P  QQP  G      K  A   GH++       PP       +P   +P        
Sbjct: 301 PSKPPIQQPTPG------KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354

Query: 298 GDGETKPSQGPADGSRPEPQ-----RPRNRPYFQRRRQQAPG----PQQAPGPRQPAAPE 348
             G TKP   P   ++P  Q     +P +     +   Q PG    P Q PGP +P   +
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414

Query: 349 TSAP 352
              P
Sbjct: 415 VGTP 418



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 59/247 (23%), Positives = 86/247 (34%), Gaps = 36/247 (14%)

Query: 136 RSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPM 195
           R     +T + D+V GE               VK S  +P++   ++  P  P    P  
Sbjct: 276 RDASRPQTKQADIVRGES--------------VKPSLPSPSKPPIQQPTPGKPPAQQPGH 321

Query: 196 VAEIPSAGTGPGSKGERAEDSGQRPRRWCPP--PFFYRRRFVR--GP-RPPNQQQPIE-- 248
               P     P       +   Q+P    PP  P    +   +  GP +PP QQ   E  
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381

Query: 249 GTDRVEPKETAPLEG-----HQQQGDERVP--------PPRFRPRYRRPFR-PRPRQQPT 294
            +++  PK  A   G      QQ G  + P        P   +P  + P + P P + P 
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 295 TEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVN 354
            + G G+  P+Q    G     Q    +P  Q      P PQQ    + P     SA   
Sbjct: 442 QQPGPGKI-PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500

Query: 355 SGDPTTT 361
           S  P +T
Sbjct: 501 SQQPGST 507



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 12/117 (10%)

Query: 239 RPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPR----FRPRYRRPFRPRPRQQPT 294
           +PP   +PI+G  +    + A L     Q D   P  +     R    +P  P P + P 
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLP---LQRDASRPQTKQADIVRGESVKPSLPSPSKPPI 306

Query: 295 TEGGDGETKPSQGPADGSRPEPQRPRNRPY-FQRRRQQAPG----PQQAPGPRQPAA 346
            +   G+    Q   + S+P P +P  +P    +   Q PG    P Q PG  +P A
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPA------TAVSGTPAPPARSQ 84
           P  A  P +  G+        GPA  +P  PGS  P +        +A   +PA P+  Q
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553

Query: 85  ADKPV 89
           + KPV
Sbjct: 554 STKPV 558



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)

Query: 143  TVEFDVVEGEKGAEATNV--TGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIP 200
            T+E   V    G   T +  T P  VP K S        + R  P  P +AP P++ ++P
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520

Query: 201  SAGTGP 206
            +    P
Sbjct: 2521 TTTQKP 2526



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 50/213 (23%), Positives = 73/213 (34%), Gaps = 49/213 (23%)

Query: 167 PVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPP 226
           P  G + +P   K+   IPRP S +       I   G    SKG++  D  Q+       
Sbjct: 807 PPTGEKVSPFDSKA---IPRPASDSKI-----ISHPGPSSESKGQKQVDPVQKKEE---- 854

Query: 227 PFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFR 286
                      P+    +   +   +  PK +    G +    + VP P+  P+ +   R
Sbjct: 855 -----------PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903

Query: 287 ----------PRPRQQPTTEG--------GDGETKPSQGPADGSRPEPQRPRNRPYFQRR 328
                       P+ QPTT          G G +  SQ     S      P ++      
Sbjct: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963

Query: 329 RQQAPGPQQAP---GP-----RQPAAPETSAPV 353
            +QAP P Q P   GP     + P AP  S PV
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 19/187 (10%)

Query: 185 PRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQ 244
           P P ++A PP V + P+   GP     +   +   P+     P         GP     Q
Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT---PKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 245 QPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFR-PRYRRPFRPRPRQQPTTEGGD---- 299
           QP  G  ++  ++  P +   QQ     PP +   P    P +P P + P  + G     
Sbjct: 443 QP--GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500

Query: 300 ----GETKPSQGPADGSRPEPQRPRN-RPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVN 354
               G TKP       ++P PQ+P + +P  Q+     P  QQ P P +P+A +++ PV+
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ-PSPAKPSAQQSTKPVS 559

Query: 355 ---SGDP 358
              SG P
Sbjct: 560 QTGSGKP 566



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/174 (24%), Positives = 64/174 (36%), Gaps = 24/174 (13%)

Query: 188 PSVAPPPMVAEIPSAGTG--PGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQ 245
           P+ AP P    +   G G  P  +    + S Q+     PP        + GP  P  QQ
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ------LPGPAKPPPQQ 483

Query: 246 PIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPS 305
           P  G  +  P++    +   QQ     PPP+       P +P P+Q  +T+      +P 
Sbjct: 484 P--GPAKPPPQQPGSAKPPSQQPGSTKPPPQ----QPGPAKPSPQQPGSTK--PPSQQPG 535

Query: 306 QGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPT 359
                  +P P +P          QQ+  P    G  +P  P T +P     P+
Sbjct: 536 SAKPSAQQPSPAKP--------SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 15/124 (12%)

Query: 238 PRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEG 297
           P  P  QQP  G      K  A   GH++       PP       +P   +P        
Sbjct: 301 PSKPPIQQPTPG------KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354

Query: 298 GDGETKPSQGPADGSRPEPQ-----RPRNRPYFQRRRQQAPG----PQQAPGPRQPAAPE 348
             G TKP   P   ++P  Q     +P +     +   Q PG    P Q PGP +P   +
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414

Query: 349 TSAP 352
              P
Sbjct: 415 VGTP 418



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 59/247 (23%), Positives = 86/247 (34%), Gaps = 36/247 (14%)

Query: 136 RSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPM 195
           R     +T + D+V GE               VK S  +P++   ++  P  P    P  
Sbjct: 276 RDASRPQTKQADIVRGES--------------VKPSLPSPSKPPIQQPTPGKPPAQQPGH 321

Query: 196 VAEIPSAGTGPGSKGERAEDSGQRPRRWCPP--PFFYRRRFVR--GP-RPPNQQQPIE-- 248
               P     P       +   Q+P    PP  P    +   +  GP +PP QQ   E  
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381

Query: 249 GTDRVEPKETAPLEG-----HQQQGDERVP--------PPRFRPRYRRPFR-PRPRQQPT 294
            +++  PK  A   G      QQ G  + P        P   +P  + P + P P + P 
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 295 TEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVN 354
            + G G+  P+Q    G     Q    +P  Q      P PQQ    + P     SA   
Sbjct: 442 QQPGPGKI-PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500

Query: 355 SGDPTTT 361
           S  P +T
Sbjct: 501 SQQPGST 507



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 12/117 (10%)

Query: 239 RPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPR----FRPRYRRPFRPRPRQQPT 294
           +PP   +PI+G  +    + A L     Q D   P  +     R    +P  P P + P 
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLP---LQRDASRPQTKQADIVRGESVKPSLPSPSKPPI 306

Query: 295 TEGGDGETKPSQGPADGSRPEPQRPRNRPY-FQRRRQQAPG----PQQAPGPRQPAA 346
            +   G+    Q   + S+P P +P  +P    +   Q PG    P Q PG  +P A
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPA------TAVSGTPAPPARSQ 84
           P  A  P +  G+        GPA  +P  PGS  P +        +A   +PA P+  Q
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553

Query: 85  ADKPV 89
           + KPV
Sbjct: 554 STKPV 558



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)

Query: 143  TVEFDVVEGEKGAEATNV--TGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIP 200
            T+E   V    G   T +  T P  VP K S        + R  P  P +AP P++ ++P
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520

Query: 201  SAGTGP 206
            +    P
Sbjct: 2521 TTTQKP 2526



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 50/213 (23%), Positives = 73/213 (34%), Gaps = 49/213 (23%)

Query: 167 PVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPP 226
           P  G + +P   K+   IPRP S +       I   G    SKG++  D  Q+       
Sbjct: 807 PPTGEKVSPFDSKA---IPRPASDSKI-----ISHPGPSSESKGQKQVDPVQKKEE---- 854

Query: 227 PFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFR 286
                      P+    +   +   +  PK +    G +    + VP P+  P+ +   R
Sbjct: 855 -----------PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903

Query: 287 ----------PRPRQQPTTEG--------GDGETKPSQGPADGSRPEPQRPRNRPYFQRR 328
                       P+ QPTT          G G +  SQ     S      P ++      
Sbjct: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963

Query: 329 RQQAPGPQQAP---GP-----RQPAAPETSAPV 353
            +QAP P Q P   GP     + P AP  S PV
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 61/201 (30%), Positives = 77/201 (38%), Gaps = 41/201 (20%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPP-SVAPPPMVAE----IPSAGTGPGSKGERAEDSG 217
           P G P+      P R  S    P+ P S A PP   +     P AG GPG+       + 
Sbjct: 499 PAGSPL------PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG-GPGAPPAARPPAS 551

Query: 218 QRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPP-PR 276
             P+R   PP   R+  V GP PP                 AP  G Q+QG  + PP P 
Sbjct: 552 PSPQRQAGPPQATRQTSVSGPAPPK-------------ASGAPPGGQQRQGPPQKPPGPA 598

Query: 277 FRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQ 336
              R      P PR  P T     + +PS GP    RP+PQ        Q+  Q  P P 
Sbjct: 599 GPTRQASQAGPVPRTGPPT---TQQPRPS-GPGPAGRPKPQ------LAQKPSQDVPPPA 648

Query: 337 QA-----PGPRQPAAPETSAP 352
            A     P P+  A+P  + P
Sbjct: 649 TAAAGGPPHPQLKASPAQAQP 669



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/209 (25%), Positives = 73/209 (34%), Gaps = 24/209 (11%)

Query: 164 GGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKG----ERAEDSGQR 219
           G  P  G+   P  R++ +    PP+   PP     P  G GP  +G    +R    GQ+
Sbjct: 434 GQTPSPGA--LPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ 491

Query: 220 PRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRP 279
                 PP          P P     P     +   +   P +G  +Q       P   P
Sbjct: 492 HLSGLGPP-------AGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP 544

Query: 280 RYRRPFRPRPRQQP--------TTEGGDGETKPSQGPADGSRPE--PQRPRNRPYFQRRR 329
             R P  P P++Q         T+  G    K S  P  G + +  PQ+P       R+ 
Sbjct: 545 AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604

Query: 330 QQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
            QA GP    GP     P  S P  +G P
Sbjct: 605 SQA-GPVPRTGPPTTQQPRPSGPGPAGRP 632



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 287 PRPRQQPTTEG-GDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPA 345
           PR RQ+  + G G     PS G     R   Q+P   P  QR   Q   PQ  PGP++  
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478

Query: 346 APETSAPVNSG 356
            P    P   G
Sbjct: 479 PPLQQRPPPQG 489



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 15/120 (12%)

Query: 252 RVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPS---QGP 308
           R   ++ +P  G   Q       P  R   ++P  P  +Q+P  +GG  +  P    QGP
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479

Query: 309 ADGSRPEPQRPRN-----RPYFQRRRQQAPGPQQAP-GPRQPAAPET------SAPVNSG 356
               RP PQ  ++      P      Q+ P P  AP  P   AAP T      S PV  G
Sbjct: 480 PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 19/74 (25%)

Query: 30  VPVPAGEPQKGGGAGG----GGGAASGPAAGTPSA-PGSRTPGNPA-------------T 71
           +P P   PQ+          G G  S P AG P A P +R P +P+             T
Sbjct: 508 LPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQT 567

Query: 72  AVSGTPAPPARSQA 85
           +VSG PAPP  S A
Sbjct: 568 SVSG-PAPPKASGA 580



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 26/85 (30%), Positives = 29/85 (34%), Gaps = 8/85 (9%)

Query: 7   AAGATAVPAATVPATAAGVVAVVVP-------VPAGEPQKGGGAGGGGGAASGPAAGTPS 59
           A G  A PAA  PA+ +       P       V    P K  GA  GG    GP    P 
Sbjct: 537 AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596

Query: 60  APGSRTPGNPATAVSGTPAPPARSQ 84
             G     + A  V  T  PP   Q
Sbjct: 597 PAGPTRQASQAGPVPRT-GPPTTQQ 620


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 79/339 (23%), Positives = 106/339 (31%), Gaps = 36/339 (10%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNP-----------ATAVSGTPAPPA 81
           P G P +GG    G      P    P    SR+P +P                G P PP 
Sbjct: 78  PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 137

Query: 82  RSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDG 141
           + Q   P    +  G           G   + D K           +  P +     G  
Sbjct: 138 KPQGPPPQGGNKPQGPPP---PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ-----GGN 189

Query: 142 ETVEFDVVEGE-KGAEATNVTGPGGVPVKGSRYAP-----NRRKSRRFIPRPPSVAPPPM 195
           +        G+ +G        P G P  G    P     N+ +S R  P  P   PPP 
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ-GPPPQ 248

Query: 196 VAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPP-NQQQPIEGTDRVE 254
               P     P  K +     G    +  PPP        +GP P    +     +   +
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-----GKPQGPPPQGGSKSRSSRSPPGK 303

Query: 255 PKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGS-R 313
           P+   P  G+Q QG    PPP  +P+   P      Q P   G      P  G    S R
Sbjct: 304 PQGPPPQGGNQPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360

Query: 314 PEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAP 352
             P +P+  P  +    Q P P     P+QP AP    P
Sbjct: 361 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 399



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 58/224 (25%), Positives = 76/224 (33%), Gaps = 35/224 (15%)

Query: 163 PGGVPVKGSRYAP-----NRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSG 217
           P G P  G    P     N+ +S R  P  P   PPP     P     P  K +     G
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQG 208

Query: 218 QRPRRWCPPPFFYRRRFVRGPRPP--NQQQPIEGTDRVEPKETAPLEGHQQQGDE----- 270
               +  PPP        +GP P   N+ Q        +P+   P  G+Q QG       
Sbjct: 209 GNKPQGPPPP-----GKPQGPPPQGDNKSQSARSPPG-KPQGPPPQGGNQPQGPPPPPGK 262

Query: 271 -RVPPPRFRPRYRRPFRPRPRQQPTTEGGDGET-------KPSQGPADGSR------PEP 316
            + PPP+   + + P  P   Q P  +GG           KP   P  G        P P
Sbjct: 263 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322

Query: 317 QRPRNRPYFQRRRQQAPGPQQAP--GPRQPAAPETSAPVNSGDP 358
            +P+  P     + Q P P   P   P Q  +   SA    G P
Sbjct: 323 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 50/187 (26%), Positives = 70/187 (37%), Gaps = 24/187 (12%)

Query: 185 PRPPSV--APPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYR------RRFVR 236
           P PP     PPP   +  S  + PG         G +P+   PPP   +          +
Sbjct: 92  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151

Query: 237 GPRPPNQQQ--PIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPT 294
           GP PP + Q  P +G ++     + P       G  + PPP+   + + P  P P  +P 
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPP-------GKPQGPPPQGGNQPQGP--PPPPGKPQ 202

Query: 295 TEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPR---QPAAPETSA 351
                G  KP QGP    +P+   P+     Q  R   PG  Q P P+   QP  P    
Sbjct: 203 GPPPQGGNKP-QGPPPPGKPQGPPPQGDNKSQSAR-SPPGKPQGPPPQGGNQPQGPPPPP 260

Query: 352 PVNSGDP 358
               G P
Sbjct: 261 GKPQGPP 267



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 73/325 (22%), Positives = 101/325 (31%), Gaps = 84/325 (25%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKPVLAI 92
           P G P +GG    G  +  G   G P   G++          G P PP + Q   P    
Sbjct: 36  PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQP--------QGPPPPPGKPQGPPP---- 83

Query: 93  QVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGE 152
                                         Q   K   P    +  G          +G+
Sbjct: 84  ------------------------------QGGNKPQGPPPPGKPQGPPP-------QGD 106

Query: 153 KGAEATNVTG-PGGVPVKGSRYAPNRRKSRRFIPRPPSVAPP-----PMVAEIPSAGTGP 206
           K     +  G P G P +G     N+ +     P  P   PP     P     P    GP
Sbjct: 107 KSRSPRSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 162

Query: 207 GSKGERAEDSGQRP--RRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGH 264
             +G+    S + P  +   PPP        +G   P    P  G    +P+   P  G+
Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPP--------QGGNQPQGPPPPPG----KPQGPPPQGGN 210

Query: 265 QQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQG--PADGSRPEPQRPRNR 322
           + QG    PPP  +P+   P      Q   +  G  +  P QG     G  P P +P+  
Sbjct: 211 KPQG----PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266

Query: 323 PYFQRRRQQAPGPQQAPGPRQPAAP 347
           P      Q    PQ  P P +P  P
Sbjct: 267 P-----PQGGNKPQGPPPPGKPQGP 286



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 76/351 (21%), Positives = 109/351 (31%), Gaps = 80/351 (22%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKPVL 90
           P P G+PQ     GG       P  G P  P  +    P       P PP + Q   P  
Sbjct: 51  PSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ-----GPPPPGKPQGPPP-- 103

Query: 91  AIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVE 150
                                + D        ++   R+ P K                +
Sbjct: 104 ---------------------QGD--------KSRSPRSPPGK---------------PQ 119

Query: 151 GEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRP--PSVAPPPMVAEIPSAGTGPGS 208
           G          GP   P K     P      +  P P  P   PP    +  S+ + PG 
Sbjct: 120 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGK 179

Query: 209 KGERAEDSGQRPRRWCPPPFFYR------RRFVRGPRPPNQQQ--PIEGTDRVE------ 254
                   G +P+   PPP   +          +GP PP + Q  P +G ++ +      
Sbjct: 180 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP 239

Query: 255 --PKETAPLEGHQQQ------GDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQ 306
             P+   P  G+Q Q      G  + PPP+   + + P  P   Q P  +GG        
Sbjct: 240 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299

Query: 307 GPADGSRPEPQ---RPRNRPYFQRRRQQAP--GPQQAPGPRQPAAPETSAP 352
            P     P PQ   +P+  P    + Q  P  G  +  GP  P  P+   P
Sbjct: 300 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 350



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 23/110 (20%)

Query: 254 EPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADG-- 311
           +P+   P  G+Q QG    PPP  +P           Q P  +GG+   KP   P  G  
Sbjct: 56  KPQGPPPQGGNQPQGP---PPPPGKP-----------QGPPPQGGN---KPQGPPPPGKP 98

Query: 312 SRPEPQRPRNR-PYFQRRRQQAPGPQ---QAPGPRQPAAPETSAPVNSGD 357
             P PQ  ++R P     + Q P PQ   Q  GP  P       P   G+
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 10/110 (9%)

Query: 253 VEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGS 312
           V  +E+  L     QG    PP         P  P   Q P  +GG+    P   P    
Sbjct: 23  VSQEESPSLIAGNPQG---APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 79

Query: 313 RPEPQ---RPRNRPYFQRRRQQAPGPQ--QAPGPRQPAAPETSAPVNSGD 357
            P PQ   +P+  P     + Q P PQ  ++  PR P       P   G+
Sbjct: 80  GPPPQGGNKPQGPP--PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 127



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 18/56 (32%), Positives = 22/56 (39%), Gaps = 7/56 (12%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKP 88
           P G PQ+ G    G      PA G P  P +   G P     G P PP   +  +P
Sbjct: 366 PQGPPQQEGNNPQG---PPPPAGGNPQQPQAPPAGQP----QGPPRPPQGGRPSRP 414


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 60/201 (29%), Positives = 77/201 (38%), Gaps = 38/201 (18%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPP-SVAPPPMVAE----IPSAGTGPGSKGERAEDSG 217
           P G P+      P R  S    P+ P S A PP   +     P AG GPG+       + 
Sbjct: 499 PAGSPL------PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG-GPGAPPAARPPAS 551

Query: 218 QRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPP-PR 276
             P+R   PP   R+  V GP PP                 AP  G Q+QG  + PP P 
Sbjct: 552 PSPQRQAGPPQATRQTSVSGPAPPK-------------ASGAPPGGQQRQGPPQKPPGPA 598

Query: 277 FRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQ 336
              R      P PR  P T     + +PS GP    RP+PQ        Q+  Q  P P 
Sbjct: 599 GPTRQASQAGPVPRTGPPT---TQQPRPS-GPGPAGRPKPQ------LAQKPSQDVPPPA 648

Query: 337 QAP--GPRQPAAPETSAPVNS 355
            A   GP  P   ++ +  N+
Sbjct: 649 TAAAGGPPHPQLNKSQSLTNA 669



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/209 (25%), Positives = 73/209 (34%), Gaps = 24/209 (11%)

Query: 164 GGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKG----ERAEDSGQR 219
           G  P  G+   P  R++ +    PP+   PP     P  G GP  +G    +R    GQ+
Sbjct: 434 GQTPSPGA--LPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ 491

Query: 220 PRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRP 279
                 PP          P P     P     +   +   P +G  +Q       P   P
Sbjct: 492 HLSGLGPP-------AGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP 544

Query: 280 RYRRPFRPRPRQQP--------TTEGGDGETKPSQGPADGSRPE--PQRPRNRPYFQRRR 329
             R P  P P++Q         T+  G    K S  P  G + +  PQ+P       R+ 
Sbjct: 545 AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604

Query: 330 QQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
            QA GP    GP     P  S P  +G P
Sbjct: 605 SQA-GPVPRTGPPTTQQPRPSGPGPAGRP 632



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 287 PRPRQQPTTEG-GDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPA 345
           PR RQ+  + G G     PS G     R   Q+P   P  QR   Q   PQ  PGP++  
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478

Query: 346 APETSAPVNSG 356
            P    P   G
Sbjct: 479 PPLQQRPPPQG 489



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 15/120 (12%)

Query: 252 RVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPS---QGP 308
           R   ++ +P  G   Q       P  R   ++P  P  +Q+P  +GG  +  P    QGP
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479

Query: 309 ADGSRPEPQRPRN-----RPYFQRRRQQAPGPQQAP-GPRQPAAPET------SAPVNSG 356
               RP PQ  ++      P      Q+ P P  AP  P   AAP T      S PV  G
Sbjct: 480 PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 19/74 (25%)

Query: 30  VPVPAGEPQKGGGAGG----GGGAASGPAAGTPSA-PGSRTPGNPA-------------T 71
           +P P   PQ+          G G  S P AG P A P +R P +P+             T
Sbjct: 508 LPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQT 567

Query: 72  AVSGTPAPPARSQA 85
           +VSG PAPP  S A
Sbjct: 568 SVSG-PAPPKASGA 580



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 26/85 (30%), Positives = 29/85 (34%), Gaps = 8/85 (9%)

Query: 7   AAGATAVPAATVPATAAGVVAVVVP-------VPAGEPQKGGGAGGGGGAASGPAAGTPS 59
           A G  A PAA  PA+ +       P       V    P K  GA  GG    GP    P 
Sbjct: 537 AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596

Query: 60  APGSRTPGNPATAVSGTPAPPARSQ 84
             G     + A  V  T  PP   Q
Sbjct: 597 PAGPTRQASQAGPVPRT-GPPTTQQ 620


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 92/392 (23%), Positives = 121/392 (30%), Gaps = 76/392 (19%)

Query: 9    GATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGG--GGAASGPAAGTPSAPGSRTP 66
            GA   PAAT P+   G      P P G P           GG A+ P  G P+ P +  P
Sbjct: 1078 GAPTPPAATPPSPKGGPAT---PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134

Query: 67   ------------GNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRND 114
                        G P T  + TP  P    A  P             + + G    +   
Sbjct: 1135 SPKGGLATPPPKGAPTTPAA-TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG 1193

Query: 115  TKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGP----GGVPVKG 170
                      A    +P+  L +               KGA  T    P    GG+    
Sbjct: 1194 APTT-----PAATPPSPKGGLAT------------PSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 171  SRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFY 230
             + AP    +    P+     PPP  A  P A T P  KG  A      P +  P P   
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP----PHKGAPNP--- 1289

Query: 231  RRRFVRGPRPPN--QQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPR 288
                V  P P       P +G     P  T P      +G    PPP+  P       P 
Sbjct: 1290 --AVVTPPSPKGGPATSPPKGAP-TPPAATPP----SPKGSPGTPPPKGAPTPPAVTPPS 1342

Query: 289  PRQQPT-------TEGG-------DGETKPSQGPADGSRP--EPQRPRNRPYFQRRRQQA 332
            P+  PT       ++GG       +G T P+  P+    P   P  P+  P     +   
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402

Query: 333  PGPQQAP-----GPRQPAAPETSAPVNSGDPT 359
              P   P      P  P   E +A  + GD T
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 85/364 (23%), Positives = 110/364 (30%), Gaps = 56/364 (15%)

Query: 9    GATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTP-- 66
            GA   PAAT P+   G  A   P  A  P         GG A+    G P+ P +  P  
Sbjct: 938  GAPTPPAATPPSPKGGP-ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996

Query: 67   -GNPAT-AVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQT 124
             G PAT +  G P PPA                            +     K        
Sbjct: 997  KGGPATPSPKGAPTPPA----------------------------VTPPSPKGSPAATPF 1028

Query: 125  AIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGS-RYAPNRRKSRRF 183
                + P         G      + +G     A  +  P G P   S + AP    +   
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 184  IPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRG--PRPP 241
             P+     P P  A +P A T P  KG  A      P +  P          +G    PP
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATP----PHKGAPTTPAATPPSPKGGLATPP 1144

Query: 242  NQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG- 300
             +  P        P  T P      +G    PPP+  P       P P+    T    G 
Sbjct: 1145 PKGAP------TTPAATPP----SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194

Query: 301  ETKPSQGPAD--GSRPEPQRPRNRPYFQRRRQQAP-GPQQAPGPR-QPAAPETSAPVNSG 356
             T P+  P    G    P  P+  P        +P G    P P+  P  P  + P   G
Sbjct: 1195 PTTPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253

Query: 357  DPTT 360
             P T
Sbjct: 1254 GPAT 1257



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 52/229 (22%), Positives = 73/229 (31%), Gaps = 35/229 (15%)

Query: 150  EGEKGAEATNVT----GPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTG 205
            +G K + AT  +     P G P   S   P   K    +  PP   P P V  +P    G
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTP-SAVTPLSPKG---VTLPPKETPTPSVVNLPFPKEG 899

Query: 206  PGSKGER------AEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETA 259
            P +   +         S  +  R  P P    +     P P     P        P  T 
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAP----KGIPASPSPKGAPTP--------PAATP 947

Query: 260  PLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKP--SQGPADGSRPEPQ 317
            P      +G    P P++ P       P P+  P T    G   P  +  P+    P   
Sbjct: 948  P----SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 318  RPRNRPYFQRRRQQAP--GPQQAPGPRQPAAPETSAPVN-SGDPTTTIL 363
             P+  P        +P   P   P P+  + P  + P +  G P  T L
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 50/216 (23%), Positives = 65/216 (30%), Gaps = 20/216 (9%)

Query: 153  KGAEATNVTGP----GGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGS 208
            KGA  T    P    GG+     + AP    +    P+     PPP  A    A T P  
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182

Query: 209  KGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQG 268
            KG  A  S   P+     P            PP+ +  +          T        +G
Sbjct: 1183 KGGLATPS---PKGAPTTP---------AATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 269  DERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG-ETKPSQGPAD---GSRPEPQRPRNRPY 324
                P P+  P       P P+  P T    G  T P+  P     G    P +    P 
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290

Query: 325  FQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPTT 360
                     GP  +P    P  P  + P   G P T
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 6/74 (8%)

Query: 10  ATAVPAAT-VPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGN 68
           A A PA   +PA+ +   A   P       KGG A      A  P A TP +P     G 
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP----KGG 976

Query: 69  PAT-AVSGTPAPPA 81
           PAT +  G P PPA
Sbjct: 977 PATPSPKGAPTPPA 990



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 76/351 (21%), Positives = 102/351 (29%), Gaps = 85/351 (24%)

Query: 19   PATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPA 78
            PAT A   A  + + +  P+K        G  + P+      P + TP +P     G PA
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP----KGGPA 955

Query: 79   PPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSV 138
             P+   A  P  A                                    +  P     S 
Sbjct: 956  TPSPKWAPTPPAA-------------------------------TPPSPKGGPA--TPSP 982

Query: 139  GDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAE 198
                T         KG  AT    P G P   +   P+ + S       P+  P P  A 
Sbjct: 983  KGAPTPPAATPPSPKGGPAT--PSPKGAPTPPAVTPPSPKGS-------PAATPFPKGAS 1033

Query: 199  IPSAGTGPGSKGERA-----EDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRV 253
             P A T P  KG  A     + +   P    P P         GP  P+    ++G    
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP-------KGGPATPS----LKGAP-T 1081

Query: 254  EPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSR 313
             P  T P      +G    P P+  P         P   P +  G   T P +G      
Sbjct: 1082 PPAATPP----SPKGGPATPSPKGAPM-------PPAATPPSPKGGLATPPHKG------ 1124

Query: 314  PEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPE----TSAPVNSGDPTT 360
              P  P   P   +     P P+ AP       P      + P   G PTT
Sbjct: 1125 -APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174


>gi|169163728 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 54/193 (27%), Positives = 71/193 (36%), Gaps = 32/193 (16%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRR 222
           P   P   +R  P R   +R +P   +  PP   A   + G    S  ER++   +RPRR
Sbjct: 59  PSPAPALPARARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQP--RRPRR 116

Query: 223 WCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYR 282
             PPP             P + +P  G  R    E APL   ++ G       R   R  
Sbjct: 117 --PPP------------APRRPRPAPGR-RKSLYEAAPLLTREKGG-------RSGRRGD 154

Query: 283 RPFRPRPRQQPTTEGGDGETKP--------SQGPADGSRPEPQRPRNRPYFQRRRQQAPG 334
           R             GG G++          S+G   G   EP+R R +P  QR    AP 
Sbjct: 155 RGGSGWSHGHTARVGGTGDSSAGLTTFPGSSRGGFSGREEEPRRERRQPSLQRSTPPAPT 214

Query: 335 PQQAPGPRQPAAP 347
                 PR PAAP
Sbjct: 215 YSPRSDPRDPAAP 227



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 5/78 (6%)

Query: 6   AAAGATAVPAATVPATAAGVVAVVVPVPAGEPQK-GGGAGGGGGAASGPAAGTPSAPGSR 64
           A + A A+PA   P       AV      G P++  GG  GG  AASG     P  P  R
Sbjct: 58  APSPAPALPARARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQPRRP--R 115

Query: 65  TPGNPATAVSGTPAPPAR 82
            P  P       PAP  R
Sbjct: 116 RP--PPAPRRPRPAPGRR 131


>gi|169163708 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 54/193 (27%), Positives = 71/193 (36%), Gaps = 32/193 (16%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRR 222
           P   P   +R  P R   +R +P   +  PP   A   + G    S  ER++   +RPRR
Sbjct: 59  PSPAPALPARARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQP--RRPRR 116

Query: 223 WCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYR 282
             PPP             P + +P  G  R    E APL   ++ G       R   R  
Sbjct: 117 --PPP------------APRRPRPAPGR-RKSLYEAAPLLTREKGG-------RSGRRGD 154

Query: 283 RPFRPRPRQQPTTEGGDGETKP--------SQGPADGSRPEPQRPRNRPYFQRRRQQAPG 334
           R             GG G++          S+G   G   EP+R R +P  QR    AP 
Sbjct: 155 RGGSGWSHGHTARVGGTGDSSAGLTTFPGSSRGGFSGREEEPRRERRQPSLQRSTPPAPT 214

Query: 335 PQQAPGPRQPAAP 347
                 PR PAAP
Sbjct: 215 YSPRSDPRDPAAP 227



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 5/78 (6%)

Query: 6   AAAGATAVPAATVPATAAGVVAVVVPVPAGEPQK-GGGAGGGGGAASGPAAGTPSAPGSR 64
           A + A A+PA   P       AV      G P++  GG  GG  AASG     P  P  R
Sbjct: 58  APSPAPALPARARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQPRRP--R 115

Query: 65  TPGNPATAVSGTPAPPAR 82
            P  P       PAP  R
Sbjct: 116 RP--PPAPRRPRPAPGRR 131


>gi|169163019 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 54/193 (27%), Positives = 71/193 (36%), Gaps = 32/193 (16%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRR 222
           P   P   +R  P R   +R +P   +  PP   A   + G    S  ER++   +RPRR
Sbjct: 59  PSPAPALPARARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQP--RRPRR 116

Query: 223 WCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYR 282
             PPP             P + +P  G  R    E APL   ++ G       R   R  
Sbjct: 117 --PPP------------APRRPRPAPGR-RKSLYEAAPLLTREKGG-------RSGRRGD 154

Query: 283 RPFRPRPRQQPTTEGGDGETKP--------SQGPADGSRPEPQRPRNRPYFQRRRQQAPG 334
           R             GG G++          S+G   G   EP+R R +P  QR    AP 
Sbjct: 155 RGDSGWSHGHTARVGGTGDSSAGLTTFPGSSRGGFSGREEEPRRERRQPSLQRSTPPAPT 214

Query: 335 PQQAPGPRQPAAP 347
                 PR PAAP
Sbjct: 215 YSPRSDPRDPAAP 227



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 5/78 (6%)

Query: 6   AAAGATAVPAATVPATAAGVVAVVVPVPAGEPQK-GGGAGGGGGAASGPAAGTPSAPGSR 64
           A + A A+PA   P       AV      G P++  GG  GG  AASG     P  P  R
Sbjct: 58  APSPAPALPARARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQPRRP--R 115

Query: 65  TPGNPATAVSGTPAPPAR 82
            P  P       PAP  R
Sbjct: 116 RP--PPAPRRPRPAPGRR 131


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 46/158 (29%), Positives = 63/158 (39%), Gaps = 22/158 (13%)

Query: 198  EIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVE--- 254
            E PS   GP S       +G  P    PPP        + PRP ++  P  G  +     
Sbjct: 871  EEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLG 930

Query: 255  --PKET-APLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGET---KPSQGP 308
              P E  AP +G QQ+  +++        +R+        + +  GG G     +P +  
Sbjct: 931  LAPTEADAPSQGRQQRRGKQLK------LFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984

Query: 309  ADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAA 346
              G RP P RPR      R R QAPG +  P PR P A
Sbjct: 985  GLGERPPP-RPR------RPRTQAPGSRADPAPRVPRA 1015



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 35/215 (16%)

Query: 152  EKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGE 211
            + G  A      GG    G R   N     R  PRP          + P +   P  +  
Sbjct: 959  DSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPR-----TQAPGSRADPAPRVP 1013

Query: 212  RA----EDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQ--QPIEGTDRVEPKETAPLEGHQ 265
            RA    E++    RR  PP    R+R  RG     +   + ++  +R+   + A     +
Sbjct: 1014 RAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFAS----E 1069

Query: 266  QQGDERVPP--PRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEPQRPRNRP 323
             + DE+ PP  P FR R  R  + +            E + +QGP +    EPQ+PR   
Sbjct: 1070 SEEDEQPPPRGPGFRGRRGRGEKRK------------EVELTQGPRED---EPQKPRKAA 1114

Query: 324  YFQRRRQQAPGPQQAPGPRQPA---APETSAPVNS 355
              +     AP   + PG  +P    +P+   P  S
Sbjct: 1115 RQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRS 1149



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 35/173 (20%)

Query: 217 GQRPRRWCPPPF---FYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVP 273
           G+RPR   PP        R+    P  P+Q    + T      + A   G Q Q  E   
Sbjct: 3   GERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL-- 60

Query: 274 PPRFRPRYRRPFRPRPR----QQPTT---EGGDGETKPSQGP----------ADGSRPEP 316
            P  +PR  R    +P     Q P++   + G  +T P + P          A+GS P+ 
Sbjct: 61  -PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQR 119

Query: 317 Q-----RPRNRPYFQRRRQQAPGPQ----QAPGPRQPAAPETSAPVNSGDPTT 360
                   R +P      +    PQ    Q P    P  P T AP+  G P T
Sbjct: 120 YILGIASSRTKPTLDETPEN---PQLEAAQLPEVDTPQGPGTGAPLRPGLPRT 169



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 4/58 (6%)

Query: 31   PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAP---PARSQA 85
            P   G      G   GGG+   PA+G   +  + TP  P+   S +PAP   PAR+QA
Sbjct: 3702 PSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP-SRSPAPERLPARAQA 3758



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 14/84 (16%)

Query: 283  RPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEPQRPR---------NRPYFQRRRQQAP 333
            +P  P+ +  P+++G  G  +P      GS+P+P   +          +P F  R   +P
Sbjct: 3692 KPATPKAKPGPSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR---SP 3747

Query: 334  GPQQAPGPRQPAAPETSAPVNSGD 357
             P++ P  R  A   T  P  +G+
Sbjct: 3748 APERLPA-RAQAKSCTKGPREAGE 3770


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 65/224 (29%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 150 EGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGS- 208
           +G KG +  N   PG   VKG++  P         PR P   P       P     PGS 
Sbjct: 390 KGSKGYQG-NSGAPGSPGVKGAKGGPG--------PRGPKGEPGRRGD--PGTKGSPGSD 438

Query: 209 --KGERAEDSGQRPRRWCPP---PFFYRRRFVRGPRPPNQQ--QPIEGTDRVEPKETAPL 261
             KGE+ +   + PR              R + GPR P     +P +   R +P +  P 
Sbjct: 439 GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP- 497

Query: 262 EGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPAD-GSRPEPQRPR 320
                +GD   P P+  P       P PR  P  +G  G   P  G  D G + EP R  
Sbjct: 498 -----RGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552

Query: 321 NRPYFQRRRQQAPGPQQAPGPRQP---AAPETSAPVNSGDPTTT 361
                ++     PGP   PGPR P     PE   P   GDP  T
Sbjct: 553 -----EKGEPADPGPPGEPGPRGPRGVPGPE-GEPGPPGDPGLT 590


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 65/224 (29%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 150 EGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGS- 208
           +G KG +  N   PG   VKG++  P         PR P   P       P     PGS 
Sbjct: 390 KGSKGYQG-NSGAPGSPGVKGAKGGPG--------PRGPKGEPGRRGD--PGTKGSPGSD 438

Query: 209 --KGERAEDSGQRPRRWCPP---PFFYRRRFVRGPRPPNQQ--QPIEGTDRVEPKETAPL 261
             KGE+ +   + PR              R + GPR P     +P +   R +P +  P 
Sbjct: 439 GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP- 497

Query: 262 EGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPAD-GSRPEPQRPR 320
                +GD   P P+  P       P PR  P  +G  G   P  G  D G + EP R  
Sbjct: 498 -----RGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552

Query: 321 NRPYFQRRRQQAPGPQQAPGPRQP---AAPETSAPVNSGDPTTT 361
                ++     PGP   PGPR P     PE   P   GDP  T
Sbjct: 553 -----EKGEPADPGPPGEPGPRGPRGVPGPE-GEPGPPGDPGLT 590


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 65/224 (29%), Positives = 83/224 (37%), Gaps = 35/224 (15%)

Query: 150 EGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGS- 208
           +G KG +  N   PG   VKG++  P         PR P   P       P     PGS 
Sbjct: 390 KGSKGYQG-NSGAPGSPGVKGAKGGPG--------PRGPKGEPGRRGD--PGTKGSPGSD 438

Query: 209 --KGERAEDSGQRPRRWCPP---PFFYRRRFVRGPRPPNQQ--QPIEGTDRVEPKETAPL 261
             KGE+ +   + PR              R + GPR P     +P +   R +P +  P 
Sbjct: 439 GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP- 497

Query: 262 EGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPAD-GSRPEPQRPR 320
                +GD   P P+  P       P PR  P  +G  G   P  G  D G + EP R  
Sbjct: 498 -----RGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552

Query: 321 NRPYFQRRRQQAPGPQQAPGPRQP---AAPETSAPVNSGDPTTT 361
                ++     PGP   PGPR P     PE   P   GDP  T
Sbjct: 553 -----EKGEPADPGPPGEPGPRGPRGVPGPE-GEPGPPGDPGLT 590


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 91/378 (24%), Positives = 123/378 (32%), Gaps = 77/378 (20%)

Query: 6   AAAGATAVPAATVPATAAGVVAVVVPVPAG--EPQKGGGAGGGGGAASGPAAGTPSAPGS 63
           AAA   A P  TV        AV  P+P G  +PQ          A   P A TP A   
Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ----------AQQPPQAPTPQAAA- 657

Query: 64  RTPGNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQ 123
                P  A +  P+P   S  +K VL      T      ++                 Q
Sbjct: 658 -----PPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSL---------------Q 697

Query: 124 TAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRF 183
             + +   ++ L + G   +V   V+             P     KG+   P    S+  
Sbjct: 698 MFLPQERSQQPLSAEGPHLSVPASVIVS--APPPAQDPAPATPVAKGAGLGPQAPDSQA- 754

Query: 184 IPRPPSVAPPPMV-AEIPSAGTGPGSKGERAEDS--GQRPRRWCPPPFFYRRRFVRGP-R 239
                S AP P + A  P  G GP S       +  G  P    P P        R P R
Sbjct: 755 -----SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHP-------TRPPSR 802

Query: 240 PPNQQQPIEGTDRVEPKETAP-------LEG-HQQQGDERVPPPRFRPRYRRPFRPRPRQ 291
           PP++ Q +       P    P       L G    Q    VPPP   P    P  P+P  
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862

Query: 292 QPTTEGGDGETKP---------SQGPADGSRPEPQRPRNRPY-FQRRRQQAPGPQQAPGP 341
           +P ++  +G   P         S   A  S    + P   P  FQ +   + GP ++P P
Sbjct: 863 RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTP 922

Query: 342 -------RQPAAPETSAP 352
                   +PAAP    P
Sbjct: 923 PPTLHLVPEPAAPPPPPP 940


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 6   AAAGATAVPA---ATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG 62
           AAAGA A  A   A   A AA  VA      A +P   GG G GGG      AG+P A G
Sbjct: 186 AAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGG------AGSPGAQG 239

Query: 63  SRTP--GNPATAVSGTP--APPARSQADKPVL 90
           ++ P  GNPA  + G+    P  ++ + +P++
Sbjct: 240 TKYPEHGNPAILLMGSANGGPVVKTDSQQPLV 271


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 63/225 (28%), Positives = 81/225 (36%), Gaps = 32/225 (14%)

Query: 147 DVVEGEKGAEATNVTGPGG-VPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTG 205
           DV    + AEAT  + P      KGS   PN      F PR   V PPP      S    
Sbjct: 261 DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF-PRSFKV-PPPTPVRTSSIPVQ 318

Query: 206 PGSKGERAEDSGQR--PRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEP---KETAP 260
              +  R E+   +  P R   PP F+ R       P +Q  P    +   P   K TAP
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIR-------PASQVYPDRAPEPDCPGELKATAP 371

Query: 261 ----LEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEP 316
               L   Q Q DER   P   P    P  P P   P              PA    P  
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLP-----------PAAPPLPCA 420

Query: 317 QRPRNRP--YFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPT 359
           Q+  + P  + +  +  +P  +  P P  P    +SAPV+  DP+
Sbjct: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 49/203 (24%), Positives = 65/203 (32%), Gaps = 43/203 (21%)

Query: 185 PRPPSVAP----------PPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRF 234
           P PPS+AP          PP     PS  T P         +   P    PPP       
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP---PPP------- 230

Query: 235 VRGPRPPNQQQPIEGTDRVEP-------KETAPLEGHQQQGDERVPP------------- 274
           V  P PP    P     R+ P       K    L G Q +     PP             
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290

Query: 275 -PRFRPRYRRPFR-PRPRQQPTTEGGDGETKPSQGPADG-SRPEPQRPRNRPYFQRRRQQ 331
            P     + R F+ P P    T+     E + +    +G ++  P R    P F  R   
Sbjct: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350

Query: 332 APGPQQAPGPRQPAAPETSAPVN 354
              P +AP P  P   + +AP +
Sbjct: 351 QVYPDRAPEPDCPGELKATAPAS 373



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)

Query: 4   VEAAAG-ATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG 62
           ++A +G A A  A T+P T + ++A     PAG+P+K             PA+   S P 
Sbjct: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK-------------PASQEVSTPS 729

Query: 63  -SRTPGNPATAVSGTPAPPARSQADKP 88
            +R  G+P+ A +  P   ARS A  P
Sbjct: 730 QARGEGSPSEA-TRLPTQGARSSAAFP 755


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 63/225 (28%), Positives = 81/225 (36%), Gaps = 32/225 (14%)

Query: 147 DVVEGEKGAEATNVTGPGG-VPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTG 205
           DV    + AEAT  + P      KGS   PN      F PR   V PPP      S    
Sbjct: 261 DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF-PRSFKV-PPPTPVRTSSIPVQ 318

Query: 206 PGSKGERAEDSGQR--PRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEP---KETAP 260
              +  R E+   +  P R   PP F+ R       P +Q  P    +   P   K TAP
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIR-------PASQVYPDRAPEPDCPGELKATAP 371

Query: 261 ----LEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEP 316
               L   Q Q DER   P   P    P  P P   P              PA    P  
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLP-----------PAAPPLPCA 420

Query: 317 QRPRNRP--YFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPT 359
           Q+  + P  + +  +  +P  +  P P  P    +SAPV+  DP+
Sbjct: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 49/203 (24%), Positives = 65/203 (32%), Gaps = 43/203 (21%)

Query: 185 PRPPSVAP----------PPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRF 234
           P PPS+AP          PP     PS  T P         +   P    PPP       
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP---PPP------- 230

Query: 235 VRGPRPPNQQQPIEGTDRVEP-------KETAPLEGHQQQGDERVPP------------- 274
           V  P PP    P     R+ P       K    L G Q +     PP             
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290

Query: 275 -PRFRPRYRRPFR-PRPRQQPTTEGGDGETKPSQGPADG-SRPEPQRPRNRPYFQRRRQQ 331
            P     + R F+ P P    T+     E + +    +G ++  P R    P F  R   
Sbjct: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350

Query: 332 APGPQQAPGPRQPAAPETSAPVN 354
              P +AP P  P   + +AP +
Sbjct: 351 QVYPDRAPEPDCPGELKATAPAS 373



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)

Query: 4   VEAAAG-ATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG 62
           ++A +G A A  A T+P T + ++A     PAG+P+K             PA+   S P 
Sbjct: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK-------------PASQEVSTPS 729

Query: 63  -SRTPGNPATAVSGTPAPPARSQADKP 88
            +R  G+P+ A +  P   ARS A  P
Sbjct: 730 QARGEGSPSEA-TRLPTQGARSSAAFP 755


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 63/225 (28%), Positives = 81/225 (36%), Gaps = 32/225 (14%)

Query: 147 DVVEGEKGAEATNVTGPGG-VPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTG 205
           DV    + AEAT  + P      KGS   PN      F PR   V PPP      S    
Sbjct: 261 DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF-PRSFKV-PPPTPVRTSSIPVQ 318

Query: 206 PGSKGERAEDSGQR--PRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEP---KETAP 260
              +  R E+   +  P R   PP F+ R       P +Q  P    +   P   K TAP
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIR-------PASQVYPDRAPEPDCPGELKATAP 371

Query: 261 ----LEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEP 316
               L   Q Q DER   P   P    P  P P   P              PA    P  
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLP-----------PAAPPLPCA 420

Query: 317 QRPRNRP--YFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDPT 359
           Q+  + P  + +  +  +P  +  P P  P    +SAPV+  DP+
Sbjct: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 49/203 (24%), Positives = 65/203 (32%), Gaps = 43/203 (21%)

Query: 185 PRPPSVAP----------PPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRF 234
           P PPS+AP          PP     PS  T P         +   P    PPP       
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP---PPP------- 230

Query: 235 VRGPRPPNQQQPIEGTDRVEP-------KETAPLEGHQQQGDERVPP------------- 274
           V  P PP    P     R+ P       K    L G Q +     PP             
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290

Query: 275 -PRFRPRYRRPFR-PRPRQQPTTEGGDGETKPSQGPADG-SRPEPQRPRNRPYFQRRRQQ 331
            P     + R F+ P P    T+     E + +    +G ++  P R    P F  R   
Sbjct: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350

Query: 332 APGPQQAPGPRQPAAPETSAPVN 354
              P +AP P  P   + +AP +
Sbjct: 351 QVYPDRAPEPDCPGELKATAPAS 373



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)

Query: 4   VEAAAG-ATAVPAATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG 62
           ++A +G A A  A T+P T + ++A     PAG+P+K             PA+   S P 
Sbjct: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK-------------PASQEVSTPS 729

Query: 63  -SRTPGNPATAVSGTPAPPARSQADKP 88
            +R  G+P+ A +  P   ARS A  P
Sbjct: 730 QARGEGSPSEA-TRLPTQGARSSAAFP 755


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 89/369 (24%), Positives = 121/369 (32%), Gaps = 88/369 (23%)

Query: 16  ATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPA----- 70
           A V  +  G V    P     P   G  G G G  S P A +P A GS +PG+P      
Sbjct: 661 ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPS-PGAHSPRA-GSISPGSPPYPQSR 718

Query: 71  -------TAVSGTPAP-PARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVH 122
                  T   G   P P    +  P+ + + L  V W    +G+  + R+         
Sbjct: 719 KLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP-------- 770

Query: 123 QTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRR 182
                R+ P                       + ++ ++GP   P+  S     +  +RR
Sbjct: 771 -----RDAPC----------------------SASSELSGPS-TPLHTSSPVQGKESTRR 802

Query: 183 FIPRPPSVAPP----PMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGP 238
              R P+ AP     P  A  P +  G G   E    SG  P    P P       V   
Sbjct: 803 QDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPL--APSP-------VSPT 853

Query: 239 RPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGG 298
            PP+            P+E +P  GH      R P P   P  R      PR  P +  G
Sbjct: 854 FPPSSPSDW-------PQERSP-GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDG 905

Query: 299 DGETK-PSQGPADGSRPEPQRPRNRPYFQR---------------RRQQAPGPQQAPGPR 342
              T  PSQ P   + PEP +    P F                  ++  PGP Q PGP 
Sbjct: 906 SPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPW 965

Query: 343 QPAAPETSA 351
            P    + A
Sbjct: 966 GPEQASSPA 974



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 11/66 (16%)

Query: 299 DGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
           DG    ++GP DGS          PY Q +R     P  AP P  P  P  S   +SG  
Sbjct: 344 DGSLTHTRGPLDGS----------PYAQVQRPPRQTPP-APSPEPPPPPMLSVSSDSGHS 392

Query: 359 TTTILE 364
           +T   E
Sbjct: 393 STLTTE 398



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 167 PVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPS-AGTGPGSKGERAEDSGQRP 220
           P+ GS YA  +R  R+  P P    PPP +  + S +G       E A +S  RP
Sbjct: 353 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 407



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 27/112 (24%), Positives = 38/112 (33%), Gaps = 3/112 (2%)

Query: 250 TDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPA 309
           T R+ P E  P       G     P    P    P    P   P++     + +   G +
Sbjct: 813 TQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 872

Query: 310 DGSRPEPQRPRNRPYFQRRRQQAP-GPQQAP--GPRQPAAPETSAPVNSGDP 358
           DG+ P    P   P  +    Q P GP  +P   P  P   +    V S +P
Sbjct: 873 DGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEP 924


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 89/369 (24%), Positives = 121/369 (32%), Gaps = 88/369 (23%)

Query: 16   ATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPA----- 70
            A V  +  G V    P     P   G  G G G  S P A +P A GS +PG+P      
Sbjct: 785  ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPS-PGAHSPRA-GSISPGSPPYPQSR 842

Query: 71   -------TAVSGTPAP-PARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVH 122
                   T   G   P P    +  P+ + + L  V W    +G+  + R+         
Sbjct: 843  KLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP-------- 894

Query: 123  QTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRR 182
                 R+ P                       + ++ ++GP   P+  S     +  +RR
Sbjct: 895  -----RDAPC----------------------SASSELSGPS-TPLHTSSPVQGKESTRR 926

Query: 183  FIPRPPSVAPP----PMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGP 238
               R P+ AP     P  A  P +  G G   E    SG  P    P P       V   
Sbjct: 927  QDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPL--APSP-------VSPT 977

Query: 239  RPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGG 298
             PP+            P+E +P  GH      R P P   P  R      PR  P +  G
Sbjct: 978  FPPSSPSDW-------PQERSP-GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDG 1029

Query: 299  DGETK-PSQGPADGSRPEPQRPRNRPYFQR---------------RRQQAPGPQQAPGPR 342
               T  PSQ P   + PEP +    P F                  ++  PGP Q PGP 
Sbjct: 1030 SPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPW 1089

Query: 343  QPAAPETSA 351
             P    + A
Sbjct: 1090 GPEQASSPA 1098



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 11/66 (16%)

Query: 299 DGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
           DG    ++GP DGS          PY Q +R     P  AP P  P  P  S   +SG  
Sbjct: 468 DGSLTHTRGPLDGS----------PYAQVQRPPRQTPP-APSPEPPPPPMLSVSSDSGHS 516

Query: 359 TTTILE 364
           +T   E
Sbjct: 517 STLTTE 522



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 167 PVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPS-AGTGPGSKGERAEDSGQRP 220
           P+ GS YA  +R  R+  P P    PPP +  + S +G       E A +S  RP
Sbjct: 477 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 27/112 (24%), Positives = 38/112 (33%), Gaps = 3/112 (2%)

Query: 250  TDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPA 309
            T R+ P E  P       G     P    P    P    P   P++     + +   G +
Sbjct: 937  TQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 996

Query: 310  DGSRPEPQRPRNRPYFQRRRQQAP-GPQQAP--GPRQPAAPETSAPVNSGDP 358
            DG+ P    P   P  +    Q P GP  +P   P  P   +    V S +P
Sbjct: 997  DGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEP 1048


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 89/369 (24%), Positives = 121/369 (32%), Gaps = 88/369 (23%)

Query: 16   ATVPATAAGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPA----- 70
            A V  +  G V    P     P   G  G G G  S P A +P A GS +PG+P      
Sbjct: 795  ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPS-PGAHSPRA-GSISPGSPPYPQSR 852

Query: 71   -------TAVSGTPAP-PARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVH 122
                   T   G   P P    +  P+ + + L  V W    +G+  + R+         
Sbjct: 853  KLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP-------- 904

Query: 123  QTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRR 182
                 R+ P                       + ++ ++GP   P+  S     +  +RR
Sbjct: 905  -----RDAPC----------------------SASSELSGPS-TPLHTSSPVQGKESTRR 936

Query: 183  FIPRPPSVAPP----PMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGP 238
               R P+ AP     P  A  P +  G G   E    SG  P    P P       V   
Sbjct: 937  QDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPL--APSP-------VSPT 987

Query: 239  RPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGG 298
             PP+            P+E +P  GH      R P P   P  R      PR  P +  G
Sbjct: 988  FPPSSPSDW-------PQERSP-GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDG 1039

Query: 299  DGETK-PSQGPADGSRPEPQRPRNRPYFQR---------------RRQQAPGPQQAPGPR 342
               T  PSQ P   + PEP +    P F                  ++  PGP Q PGP 
Sbjct: 1040 SPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPW 1099

Query: 343  QPAAPETSA 351
             P    + A
Sbjct: 1100 GPEQASSPA 1108



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 11/66 (16%)

Query: 299 DGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
           DG    ++GP DGS          PY Q +R     P  AP P  P  P  S   +SG  
Sbjct: 478 DGSLTHTRGPLDGS----------PYAQVQRPPRQTPP-APSPEPPPPPMLSVSSDSGHS 526

Query: 359 TTTILE 364
           +T   E
Sbjct: 527 STLTTE 532



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 167 PVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPS-AGTGPGSKGERAEDSGQRP 220
           P+ GS YA  +R  R+  P P    PPP +  + S +G       E A +S  RP
Sbjct: 487 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 27/112 (24%), Positives = 38/112 (33%), Gaps = 3/112 (2%)

Query: 250  TDRVEPKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPA 309
            T R+ P E  P       G     P    P    P    P   P++     + +   G +
Sbjct: 947  TQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 1006

Query: 310  DGSRPEPQRPRNRPYFQRRRQQAP-GPQQAP--GPRQPAAPETSAPVNSGDP 358
            DG+ P    P   P  +    Q P GP  +P   P  P   +    V S +P
Sbjct: 1007 DGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEP 1058


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 50/199 (25%), Positives = 67/199 (33%), Gaps = 43/199 (21%)

Query: 188 PSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPI 247
           P   PPP     P    GP  +G      G + +   PPP     R  +G        P 
Sbjct: 47  PQRPPPP-----PGKPQGPPPQG------GNQSQGPPPPPGKPEGRPPQGGNQSQGPPPH 95

Query: 248 EGTDRVEPKETAPLEGHQQQGD-------ERVPPPRFRPRYRRPFRPRPRQQPTTEGGDG 300
            G    +P+   P  G+Q QG        ER PP      +R P  P   ++P  +GG+ 
Sbjct: 96  PG----KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQ 151

Query: 301 ETKPSQGPADGSRPEPQ-------------RPRNRPYFQRRRQQAPGPQQAP-------- 339
              P   P     P PQ             +P+  P  +  + Q P P   P        
Sbjct: 152 SQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGG 211

Query: 340 GPRQPAAPETSAPVNSGDP 358
            P+QP AP    P     P
Sbjct: 212 NPQQPQAPPAGKPQGPPPP 230



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 49/194 (25%), Positives = 70/194 (36%), Gaps = 21/194 (10%)

Query: 163 PGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRR 222
           P G P +G     N+ +     P  P   PP    +       PG         G + + 
Sbjct: 57  PQGPPPQGG----NQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQG 112

Query: 223 WCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDE------RVPPPR 276
             PPP    R   +G    ++  P  G    +P+   P  G+Q QG          PPP+
Sbjct: 113 TPPPPGKPERPPPQGGNQSHRPPPPPG----KPERPPPQGGNQSQGPPPHPGKPEGPPPQ 168

Query: 277 FRPRYRRPFRP--RPRQQPTTEGGDGETKPSQGPADGSRP---EPQRPRNRPYFQRRRQQ 331
              + R    P  +P+  P  EG   +  P  G   G  P    PQ+P+  P    + Q 
Sbjct: 169 EGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPP--AGKPQG 226

Query: 332 APGPQQAPGPRQPA 345
            P P Q   P +PA
Sbjct: 227 PPPPPQGGRPPRPA 240



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 23/155 (14%)

Query: 207 GSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPP--NQQQ---PIEGTDRVEPKETAPL 261
           G    R    G +P+R  PPP        +GP P   NQ Q   P  G    +P+   P 
Sbjct: 34  GKPEGRRPQGGNQPQRPPPPP-----GKPQGPPPQGGNQSQGPPPPPG----KPEGRPPQ 84

Query: 262 EGHQQQGD-------ERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRP 314
            G+Q QG        ER PP         P  P   ++P  +GG+   +P   P    RP
Sbjct: 85  GGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERP 144

Query: 315 EPQ--RPRNRPYFQRRRQQAPGPQQAPGPRQPAAP 347
            PQ       P     + + P PQ+    R   +P
Sbjct: 145 PPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP 179



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 50/195 (25%), Positives = 60/195 (30%), Gaps = 38/195 (19%)

Query: 150 EGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVA--PPPMVAEIPSAGTGPG 207
           EG          GP   P K  R  P      +  P PP     PPP           P 
Sbjct: 79  EGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPP 138

Query: 208 SKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRV-------EPKETAP 260
            K ER    G    +  PP           P  P    P EG           +P+    
Sbjct: 139 GKPERPPPQGGNQSQGPPPH----------PGKPEGPPPQEGNKSRSARSPPGKPQGPPQ 188

Query: 261 LEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGE--TKPSQGPADGSRPEPQR 318
            EG++ QG    PPP  +P           Q P   GG+ +    P  G   G  P PQ 
Sbjct: 189 QEGNKPQG----PPPPGKP-----------QGPPPAGGNPQQPQAPPAGKPQGPPPPPQ- 232

Query: 319 PRNRPYFQRRRQQAP 333
              RP    + QQ P
Sbjct: 233 -GGRPPRPAQGQQPP 246



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 19/54 (35%), Positives = 21/54 (38%), Gaps = 7/54 (12%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQ 84
           P P G+PQ    AGG       P AG P  P       P     G P  PA+ Q
Sbjct: 197 PPPPGKPQGPPPAGGNPQQPQAPPAGKPQGP-------PPPPQGGRPPRPAQGQ 243



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 8/60 (13%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG--SRTPGNPATAVSGTPAPPARSQADKP 88
           P P G+P+  G    GG  + GP    P  PG   R P        GTP PP + +   P
Sbjct: 72  PPPPGKPE--GRPPQGGNQSQGP----PPHPGKPERPPPQGGNQSQGTPPPPGKPERPPP 125



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%)

Query: 31  PVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVS--GTPAPPARSQADKP 88
           P P G+P++    GG       P  G P  P  +      +A S  G P  P + + +KP
Sbjct: 135 PPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKP 194



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 9/61 (14%)

Query: 33  PAGEPQKGGGAGGG---GGAASG--PAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADK 87
           P G PQ+ G    G    G   G  PA G P  P +   G P     G P PP   +  +
Sbjct: 183 PQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKP----QGPPPPPQGGRPPR 238

Query: 88  P 88
           P
Sbjct: 239 P 239


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 95/368 (25%), Positives = 119/368 (32%), Gaps = 57/368 (15%)

Query: 5   EAAAGATAVPAATVPATAAGVVAVV-------VPVPAGEPQKGGGAGGGG--GAASGPA- 54
           +   GA   P    PA   G            +P P G P +GG  G  G  G A  P  
Sbjct: 635 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694

Query: 55  ------------AGTPSAPGSRTP-GNPATAVSGTPAPPARSQADKPVLAIQVLGTVKWF 101
                        G+P A G + P G P T   GT  P   S    P  A    G     
Sbjct: 695 VGPRGERGFPGERGSPGAQGLQGPRGLPGT--PGTDGPKGASGPAGPPGAQGPPGLQGMP 752

Query: 102 NVRNGYGFINRNDTKEDVFVH--QTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATN 159
             R   G       + DV     + A  ++  R     +G           GEKG     
Sbjct: 753 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG---ANGEKG----E 805

Query: 160 VTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQR 219
           V  PG     G+R AP  R      P P   A P      P A   PG+KGE+ E +GQ+
Sbjct: 806 VGPPGPAGSAGARGAPGER-GETGPPGPAGFAGP------PGADGQPGAKGEQGE-AGQK 857

Query: 220 PRRWCPPPFFYRRRFVRGPR-PPNQQQP--IEGTDRVEPKETAPLEGHQQQGDERVPPPR 276
                P P        +GP   P  Q P  + G       +  P          RV PP 
Sbjct: 858 GDAGAPGP--------QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG 909

Query: 277 FRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQ 336
                  P  P P  +   +G  G++ P   P     P  Q P   P  ++      GP 
Sbjct: 910 SNGNPGPPGPPGPSGKDGPKGARGDSGP---PGRAGEPGLQGPAGPP-GEKGEPGDDGPS 965

Query: 337 QAPGPRQP 344
            A GP  P
Sbjct: 966 GAEGPPGP 973



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 89/345 (25%), Positives = 110/345 (31%), Gaps = 55/345 (15%)

Query: 31  PVPAGEPQKGGGAGGGGG----AASGPAA--GTPSAPGSRTPGNPATAVSGTPAPPARSQ 84
           P PAG P   G  G  G       SGP    G P  PG   PG+   A  G P       
Sbjct: 212 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK--PGDDGEA--GKPGKAGERG 267

Query: 85  ADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETV 144
              P  A    GT     V+   G+   +  K +        +  +P             
Sbjct: 268 PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP------------- 314

Query: 145 EFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGT 204
                 GE G+      GP G+P +  R  P      R     P  A PP     P+ G 
Sbjct: 315 ------GENGSPGP--MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG-PAGGP 365

Query: 205 G----PGSKGE------RAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVE 254
           G    PG+KGE      R  +  Q PR     P         G   P       GTD + 
Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP---------GSPGPAGASGNPGTDGIP 416

Query: 255 -PKETAPLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGETKPSQGPADGSR 313
             K +A   G    G    P PR  P  +    P   +  T E G    K  QGP     
Sbjct: 417 GAKGSAGAPGIA--GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474

Query: 314 PEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
           P   +    P  +  ++ A G     GP  P   E  AP N G P
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG-ERGAPGNRGFP 518



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 92/348 (26%), Positives = 112/348 (32%), Gaps = 73/348 (20%)

Query: 33  PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSR-------TPGNPATAVSGTPAPPARSQA 85
           P G P   G AG  G        G   APG R       TPGNP     G P PP     
Sbjct: 118 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP--PGPPGPPGPP-- 173

Query: 86  DKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVE 145
                     G    F  +   GF  +    + + V Q  +    PR      G      
Sbjct: 174 ----------GLGGNFAAQMAGGFDEKAGGAQ-LGVMQGPMGPMGPRGPPGPAGAPGPQG 222

Query: 146 FDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPSAGTG 205
           F    GE G     V+GP G                   PR P   PP    +   AG  
Sbjct: 223 FQGNPGEPG--EPGVSGPMG-------------------PRGPP-GPPGKPGDDGEAGK- 259

Query: 206 PGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAP-LEGH 264
           PG  GER     Q  R +   P     +  RG           G D  + +  AP ++G 
Sbjct: 260 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRG---------YPGLDGAKGEAGAPGVKGE 310

Query: 265 QQQGDERVPPPRFRPRYRRPFRPR--PRQQPTTEGGDGETKPSQGPADGSRPEPQRPRNR 322
                E   P    PR     R R  P       G DG+  P+ GP     P P  P   
Sbjct: 311 SGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA-GP-----PGPVGPAGG 364

Query: 323 PYF--------QRRRQQAPGPQQAPGPR-QPAAPETSAPVN-SGDPTT 360
           P F        +     A GP+ A GPR +P  P +  P   SG+P T
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT 412



 Score = 36.6 bits (83), Expect = 0.036
 Identities = 81/349 (23%), Positives = 100/349 (28%), Gaps = 71/349 (20%)

Query: 33   PAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTPAPPARSQADKPVLAI 92
            P G P K GG G  G       AG     G   P  PA +     AP  R +   P  A 
Sbjct: 775  PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA- 833

Query: 93   QVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGE 152
                           GF                     P    +    GE  E     G+
Sbjct: 834  ---------------GFAGP------------------PGADGQPGAKGEQGE----AGQ 856

Query: 153  KG-AEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEI--PSAGTG---- 205
            KG A A    GP G P           K  R    PP     P  A    P    G    
Sbjct: 857  KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916

Query: 206  PGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKETAP----- 260
            PG  G   +D  +  R    PP       ++GP  P  ++   G D     E  P     
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 261  --------LEGHQ-QQGDERVPPPRFRP-RYRRPFRPRPRQQPTTEGGDGETKPSQGPAD 310
                    L G + ++G   +P P   P +   P     R  P   G  G T P+  P  
Sbjct: 977  AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036

Query: 311  GSRPEPQRPRNRPYFQRRRQQ-----------APGPQQAPGPRQPAAPE 348
               P    P  R      +             APGP  +PGP  P   +
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 97/352 (27%), Positives = 117/352 (33%), Gaps = 104/352 (29%)

Query: 17  TVPATAAGVVAVV-VPVPAGEPQKGGGAGG-------GGGAASGP--AAGTPSAPGSR-- 64
           T PA AAG       P PAG P   G AGG       G    +GP  A G   A G R  
Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394

Query: 65  --TPGNPATA-VSGTPA----PPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKE 117
             TPG+P  A  SG P     P A+  A  P +A    G   +   R   G         
Sbjct: 395 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA----GAPGFPGPRGPPG--------- 441

Query: 118 DVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNR 177
                Q A     P+        G+T E   + G KG +     GP G P          
Sbjct: 442 ----PQGATGPLGPK--------GQTGE-PGIAGFKGEQ-----GPKGEPG--------- 474

Query: 178 RKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRG 237
                  P  P  AP P   E        G +G R E  G  P     PP         G
Sbjct: 475 -------PAGPQGAPGPAGEE--------GKRGARGEPGGVGP---IGPP---------G 507

Query: 238 PRPPNQQQPIEGTDRVEPKETAPLEGHQQQGDERVPPPRFR----PRYRRPFRPRPR--- 290
            R     +   G D +   + AP E    +G   +  P+       R   P  P  R   
Sbjct: 508 ERGAPGNRGFPGQDGLAGPKGAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 291 QQPTTEGGDGETKPSQGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGPR 342
            +P   G  G+  PS  P +  RP P  P      Q  R Q PG    PGP+
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGPPGP------QGARGQ-PGVMGFPGPK 608



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 92/353 (26%), Positives = 113/353 (32%), Gaps = 36/353 (10%)

Query: 5    EAAAGATAVPAATVPATAAGVVAVVV----PVPAGEPQKGGGAGGGGGAASGPAAGTPSA 60
            + A GA   P AT    AAG V        P P G P   G  G  G        G    
Sbjct: 884  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 61   PGSRTPGNPATAVSGTPAPPARSQADKPV----LAIQVLGTVKWFNVRNGYGFINRNDTK 116
            PG + P  P     G P     S A+ P     LA Q  G V     R   GF       
Sbjct: 944  PGLQGPAGPP-GEKGEPGDDGPSGAEGPPGPQGLAGQ-RGIVGLPGQRGERGFPGLPGPS 1001

Query: 117  EDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVK-GSRYAP 175
             +    Q A   +  R     VG           GE G E +   G  G P + G+    
Sbjct: 1002 GEPG-KQGAPGASGDRGPPGPVGPPGLTG---PAGEPGREGS--PGADGPPGRDGAAGVK 1055

Query: 176  NRRKSRRFIPRPPSVAPPPMVAEIPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFV 235
              R     +  P +  PP      P      G +G+R E   Q P     P      R +
Sbjct: 1056 GDRGETGAVGAPGAPGPPGS----PGPAGPTGKQGDRGEAGAQGPMGPSGPA---GARGI 1108

Query: 236  RGPRPPNQQQPIEGTDRVEPKETAPLEGHQQ----QGDERVPPPRFRPRYRRPFRPR-PR 290
            +GP+ P   +   G    EP E   L+GH+     QG    P P        P  P  PR
Sbjct: 1109 QGPQGPRGDKGEAG----EPGERG-LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163

Query: 291  QQPTTEGGDGETKPS--QGPADGSRPEPQRPRNRPYFQRRRQQAPGPQQAPGP 341
              P   G  G+   +   GP     P  +     P         PGP   PGP
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 4/84 (4%)

Query: 9   GATAVPAATVPATAAGVVAVVVPVPA-GEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPG 67
           GA     A  P    G      P  A G P   G  G  G A +   AG P  PG R P 
Sbjct: 381 GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 440

Query: 68  NPATAVSGTPAPPARSQADKPVLA 91
            P  A    P  P + Q  +P +A
Sbjct: 441 GPQGATG--PLGP-KGQTGEPGIA 461



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 57/225 (25%), Positives = 78/225 (34%), Gaps = 32/225 (14%)

Query: 151 GEKGAE-ATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAEIPS---AGTGP 206
           GE+G+  A  + GP G+P       P   K       PP    PP +  +P    A    
Sbjct: 705 GERGSPGAQGLQGPRGLPGTPGTDGP---KGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761

Query: 207 GSKGERAEDSGQRPRRWCPPPFFYRRRFVRGP-RPPNQQQPIEGTDRVEPKETAPLEGHQ 265
           G KG+R +   + P      P     R + GP  PP           V P   A   G +
Sbjct: 762 GPKGDRGDVGEKGPEG---APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818

Query: 266 ----QQGDERVPPPRFRPRYRRPFRPRPRQQPTTEG--------GDGETKPSQGPADGSR 313
               ++G+   P P     +  P  P    QP  +G        GD      QGP+    
Sbjct: 819 GAPGERGETGPPGPA---GFAGP--PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873

Query: 314 PEPQRPRNRPYFQRRRQQAPGPQQAPGPRQPAAPETSAPVNSGDP 358
           P+       P   R  Q  PG    PG    AA     P ++G+P
Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPG----AAGRVGPPGSNGNP 914



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 16/46 (34%), Positives = 20/46 (43%)

Query: 30   VPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSG 75
            +P P G P   G +G  G A      G P  PG   PG   +A +G
Sbjct: 1180 IPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAG 1225


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,562,514
Number of Sequences: 37866
Number of extensions: 1627494
Number of successful extensions: 23783
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 525
Number of HSP's successfully gapped in prelim test: 1181
Number of HSP's that attempted gapping in prelim test: 12710
Number of HSP's gapped (non-prelim): 9467
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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