Guide to the Human Genome
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Search of human proteins with 156119615

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156119615 myosin IXA [Homo sapiens]
         (2548 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156119615 myosin IXA [Homo sapiens]                               5068   0.0  
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                     1207   0.0  
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                      1207   0.0  
gi|118402590 myosin XV [Homo sapiens]                                 458   e-128
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     442   e-123
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     442   e-123
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     442   e-123
gi|122937512 myosin VIIB [Homo sapiens]                               439   e-122
gi|154354979 myosin X [Homo sapiens]                                  438   e-122
gi|134288915 myosin IIIB isoform 1 [Homo sapiens]                     415   e-115
gi|134288892 myosin IIIB isoform 2 [Homo sapiens]                     415   e-115
gi|145275208 myosin IIIA [Homo sapiens]                               412   e-114
gi|92859701 myosin VI [Homo sapiens]                                  398   e-110
gi|122937345 myosin VB [Homo sapiens]                                 391   e-108
gi|153945715 myosin VC [Homo sapiens]                                 388   e-107
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       385   e-106
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       385   e-106
gi|27544941 myosin IF [Homo sapiens]                                  372   e-102
gi|194328685 myosin IB isoform 1 [Homo sapiens]                       370   e-102
gi|44889481 myosin IB isoform 2 [Homo sapiens]                        370   e-102
gi|240120050 myosin IB isoform 1 [Homo sapiens]                       370   e-102
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   366   e-100
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   366   e-100
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   365   e-100
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   365   e-100
gi|4885503 myosin IA [Homo sapiens]                                   363   1e-99
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    360   1e-98
gi|51100974 myosin ID [Homo sapiens]                                  360   1e-98
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   355   3e-97
gi|124494247 myosin IC isoform b [Homo sapiens]                       351   6e-96

>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 5068 bits (13146), Expect = 0.0
 Identities = 2548/2548 (100%), Positives = 2548/2548 (100%)

Query: 1    MNINDGGRRRFEDNEHTLRIYPGAISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKC 60
            MNINDGGRRRFEDNEHTLRIYPGAISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKC
Sbjct: 1    MNINDGGRRRFEDNEHTLRIYPGAISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKC 60

Query: 61   YVLAEVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGS 120
            YVLAEVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGS
Sbjct: 61   YVLAEVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGS 120

Query: 121  LQSWLRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVG 180
            LQSWLRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVG
Sbjct: 121  LQSWLRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVG 180

Query: 181  SILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGE 240
            SILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGE
Sbjct: 181  SILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGE 240

Query: 241  SGSGKTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300
            SGSGKTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFI
Sbjct: 241  SGSGKTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300

Query: 301  QVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEE 360
            QVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEE
Sbjct: 301  QVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEE 360

Query: 361  YHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIF 420
            YHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIF
Sbjct: 361  YHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIF 420

Query: 421  SLLSAILHLGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGE 480
            SLLSAILHLGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGE
Sbjct: 421  SLLSAILHLGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGE 480

Query: 481  KLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFG 540
            KLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFG
Sbjct: 481  KLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFG 540

Query: 541  FEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLIS 600
            FEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLIS
Sbjct: 541  FEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLIS 600

Query: 601  KKPTGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYG 660
            KKPTGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYG
Sbjct: 601  KKPTGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYG 660

Query: 661  VKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGK 720
            VKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGK
Sbjct: 661  VKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGK 720

Query: 721  RNIHRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSD 780
            RNIHRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSD
Sbjct: 721  RNIHRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSD 780

Query: 781  LQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGIL 840
            LQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGIL
Sbjct: 781  LQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGIL 840

Query: 841  TRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSK 900
            TRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSK
Sbjct: 841  TRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSK 900

Query: 901  LMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQD 960
            LMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQD
Sbjct: 901  LMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQD 960

Query: 961  FVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVL 1020
            FVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVL
Sbjct: 961  FVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVL 1020

Query: 1021 RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL 1080
            RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL
Sbjct: 1021 RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL 1080

Query: 1081 LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRK 1140
            LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRK
Sbjct: 1081 LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRK 1140

Query: 1141 KIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFD 1200
            KIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFD
Sbjct: 1141 KIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFD 1200

Query: 1201 NRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLE 1260
            NRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLE
Sbjct: 1201 NRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLE 1260

Query: 1261 DLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRG 1320
            DLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRG
Sbjct: 1261 DLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRG 1320

Query: 1321 TPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNET 1380
            TPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNET
Sbjct: 1321 TPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNET 1380

Query: 1381 SSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQ 1440
            SSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQ
Sbjct: 1381 SSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQ 1440

Query: 1441 RNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEER 1500
            RNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEER
Sbjct: 1441 RNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEER 1500

Query: 1501 QKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSL 1560
            QKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSL
Sbjct: 1501 QKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSL 1560

Query: 1561 LSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKEL 1620
            LSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKEL
Sbjct: 1561 LSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKEL 1620

Query: 1621 SKTDRMGTQLNVACKLSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIP 1680
            SKTDRMGTQLNVACKLSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIP
Sbjct: 1621 SKTDRMGTQLNVACKLSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIP 1680

Query: 1681 LVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQAKLHKTMSQGEITKL 1740
            LVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQAKLHKTMSQGEITKL
Sbjct: 1681 LVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQAKLHKTMSQGEITKL 1740

Query: 1741 AVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDE 1800
            AVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDE
Sbjct: 1741 AVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDE 1800

Query: 1801 LAAYHPTPPLSPELPGSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIAS 1860
            LAAYHPTPPLSPELPGSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIAS
Sbjct: 1801 LAAYHPTPPLSPELPGSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIAS 1860

Query: 1861 VSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGKSI 1920
            VSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGKSI
Sbjct: 1861 VSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGKSI 1920

Query: 1921 RYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPK 1980
            RYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPK
Sbjct: 1921 RYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPK 1980

Query: 1981 TERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKC 2040
            TERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKC
Sbjct: 1981 TERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKC 2040

Query: 2041 CLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKS 2100
            CLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKS
Sbjct: 2041 CLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKS 2100

Query: 2101 GSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGL 2160
            GSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGL
Sbjct: 2101 GSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGL 2160

Query: 2161 QERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRC 2220
            QERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRC
Sbjct: 2161 QERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRC 2220

Query: 2221 PDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMG 2280
            PDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMG
Sbjct: 2221 PDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMG 2280

Query: 2281 KGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQI 2340
            KGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQI
Sbjct: 2281 KGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQI 2340

Query: 2341 ENLQKEKEELTFEMLVLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLAL 2400
            ENLQKEKEELTFEMLVLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLAL
Sbjct: 2341 ENLQKEKEELTFEMLVLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLAL 2400

Query: 2401 SSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYSKSPFY 2460
            SSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYSKSPFY
Sbjct: 2401 SSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYSKSPFY 2460

Query: 2461 RAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTV 2520
            RAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTV
Sbjct: 2461 RAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTV 2520

Query: 2521 MSGRRKTVDPDCTSNQQLALFGNNEFMV 2548
            MSGRRKTVDPDCTSNQQLALFGNNEFMV
Sbjct: 2521 MSGRRKTVDPDCTSNQQLALFGNNEFMV 2548


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 1207 bits (3124), Expect = 0.0
 Identities = 671/1283 (52%), Positives = 843/1283 (65%), Gaps = 104/1283 (8%)

Query: 6    GGRRRFEDNEHTLRIYPG-AISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKCYVLA 64
            G   R E   + L IYP  + +E    C + A K+ST ++VI+  I  L LD TKCYVL 
Sbjct: 7    GSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLV 66

Query: 65   EVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGSLQSW 124
            EVKE GGEEW+L+  D PV R++LWPR A +     + Y FLL+E+N DG+I Y  +Q  
Sbjct: 67   EVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKYVHMQLV 126

Query: 125  LRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILI 184
             + T  RR ++ERG LP+ QQ DFDDLC+LP+L E  LL+NL++RF  +KIYTY GSIL+
Sbjct: 127  AQATATRR-LVERGLLPR-QQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILV 184

Query: 185  VINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSG 244
             INPFKFLPIYNPKYVKMY+N QLGKLEPH++A+ADVAY+ ML+++ NQCIVISGESGSG
Sbjct: 185  AINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSG 244

Query: 245  KTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNY 304
            KTQSTNFLIH LTALSQKG+ASGVE+ ILGAGPVLEAFGNAKTAHNNNSSRFGKFIQV+Y
Sbjct: 245  KTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSY 304

Query: 305  QETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYL 364
             E+G V GA VEKYLLEKSRLV QE +ERNYHVFYYLL G SE+ER  F LKQPE+Y YL
Sbjct: 305  LESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYL 364

Query: 365  NQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLS 424
            NQ   K                    +GEDL+HDFERL+ AMEMVGFLP T++QIF++LS
Sbjct: 365  NQHNLK------------------IEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLS 406

Query: 425  AILHLGNICYKKK-TYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLI 483
            AIL+LGN+ YKK+ T R++ +++  PEVL  +S+LL+VK E+L E L  RKTVTV +KLI
Sbjct: 407  AILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLI 466

Query: 484  LPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFED 543
            LPY L+EA+T R+SMAKSLYSALFDWIV RINHALLN KD+E     LSIGVLDIFGFED
Sbjct: 467  LPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFED 526

Query: 544  YENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKP 603
            +E NSFEQFCIN+ANE+LQ+YFNQHIFKLEQEEY+ EGI+WHNI Y DN  CI+LISKKP
Sbjct: 527  FERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKP 586

Query: 604  TGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKD 663
            TGL +LLDEESNFP AT+QTLL KFK QHEDN Y     VMEPAFII+H+AGKVKY +KD
Sbjct: 587  TGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKD 646

Query: 664  FREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNI 723
            FREKN D+MRPDIVALLR S ++++  +IG+DPVAVFRWA+LRA  RAM   REAG+   
Sbjct: 647  FREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRA 706

Query: 724  HRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQG 783
             R               M S     HP      E+ +        + R      +  ++G
Sbjct: 707  ER---------AEKAAGMSSPGAQSHPE-----ELPRGASTPSEKLYRDLHNQMIKSIKG 752

Query: 784  MNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGILTRN 843
                          + W G             SLL          S   L++    + ++
Sbjct: 753  --------------LPWQG---------EDPRSLLQ---------SLSRLQKPRAFILKS 780

Query: 844  KNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLME 903
            K  K K  +PK+LL+  SLK +  +TL DR TKSLLHLHKKKKPPSISAQFQ SL+KL+E
Sbjct: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840

Query: 904  TLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVS 963
             LG+AEP+F++CIRSNAEK  L F D LVL+QLRYTGMLETVRIR+SGYS+KY+FQDF  
Sbjct: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900

Query: 964  HFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRI 1023
             F VLLP++  P +  I     K+ ++  NYQ+GKT VFLKE ERQ LQ+ LH+EV+R+I
Sbjct: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960

Query: 1024 ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQA 1083
            +LLQ WFR++L R+HFL +++A+V IQ  WR+Y  ++          A     AA  LQA
Sbjct: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRR----------ALERTQAAVYLQA 1010

Query: 1084 SWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKII 1143
            SWR + +R+ Y   + + I +Q   R + +R+  + +           S++ + + K+  
Sbjct: 1011 SWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMI----------SEKQKAEEKERE 1060

Query: 1144 LLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNRI 1203
             L++   G     + +A   Q++ E  PE            E+Q SD S  E  S +   
Sbjct: 1061 ALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEA 1120

Query: 1204 KAIE-----------ECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLV 1252
             + E           E    + S+R  RES      E    Q +  QS      +E+  +
Sbjct: 1121 PSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQS-----CKEESAL 1175

Query: 1253 RERPRSLEDLHQKKVGRAKRESR 1275
            RE  R +       +   K+ESR
Sbjct: 1176 REPSRRVTQEQGVSLLEDKKESR 1198



 Score =  449 bits (1155), Expect = e-125
 Identities = 240/561 (42%), Positives = 362/561 (64%), Gaps = 34/561 (6%)

Query: 1823 KENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNED 1882
            K  KEP  K K+ R+VKI  + + S  W+    + I + ++LK +DEFLL K+NDL ++ 
Sbjct: 1471 KRTKEPGGKGKKNRNVKIGKITV-SEKWRESVFRQITNANELKYLDEFLLNKINDLRSQK 1529

Query: 1883 SKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGK-SIRYKDLYALFEQILEKTMRLEQ 1941
                T ++ +F +A ++FR NI + YS    + +GK  + YKDL   + QI+   +  E+
Sbjct: 1530 ----TPIESLFIEATEKFRSNIKTMYS----VPNGKIHVGYKDLMENY-QIVVSNLATER 1580

Query: 1942 RDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVEEHNGHI 2001
                G+    + +N F+  LDE+   +  +D    K  K ++KKR+++    V+EHNGH+
Sbjct: 1581 ----GQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERA--VQEHNGHV 1634

Query: 2002 FKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKY----DPELS 2057
            F + Q SIP  CE C S IW+MD+A +C +CK  CHKKC  K  + CS  Y    +P + 
Sbjct: 1635 FASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVE 1694

Query: 2058 SRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117
               FGV +  LTS+  +VP+V+EKL+ ++EMHGLYTEG+YRKSG+ N+ +ELRQ L TD 
Sbjct: 1695 PGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1754

Query: 2118 ESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQL 2177
             +V L+++ IH I  V KQWLR+LP PLMTF  Y +FLRA+ L E++E +  +Y+V++ L
Sbjct: 1755 AAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHL 1814

Query: 2178 SRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTT 2237
               + N+LERLIFHLV++AL ED NRMS  ALAI+FAPC+LRCPD +DPL S++D+ K T
Sbjct: 1815 PEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1874

Query: 2238 TCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVV 2297
            TCVE+++ EQM KYK ++++IS LE AE+ A  RLSL+R++     ++ G +  P   V+
Sbjct: 1875 TCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQN-APWPLKLG-FSSPYEGVL 1932

Query: 2298 VRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEER---VLTEQIENLQKEKEELTFEM 2354
             + P   D+ EE        E ++  +++AA   E+R   +L E+I+++++EKE++T+ +
Sbjct: 1933 NKSPKTRDIQEE--------ELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRL 1984

Query: 2355 LVLEPRASDDETLESEASIGT 2375
              L+PR SD+E L+SE S  T
Sbjct: 1985 PELDPRGSDEENLDSETSAST 2005


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 1207 bits (3124), Expect = 0.0
 Identities = 671/1283 (52%), Positives = 843/1283 (65%), Gaps = 104/1283 (8%)

Query: 6    GGRRRFEDNEHTLRIYPG-AISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKCYVLA 64
            G   R E   + L IYP  + +E    C + A K+ST ++VI+  I  L LD TKCYVL 
Sbjct: 7    GSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLV 66

Query: 65   EVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGSLQSW 124
            EVKE GGEEW+L+  D PV R++LWPR A +     + Y FLL+E+N DG+I Y  +Q  
Sbjct: 67   EVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKYVHMQLV 126

Query: 125  LRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILI 184
             + T  RR ++ERG LP+ QQ DFDDLC+LP+L E  LL+NL++RF  +KIYTY GSIL+
Sbjct: 127  AQATATRR-LVERGLLPR-QQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILV 184

Query: 185  VINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSG 244
             INPFKFLPIYNPKYVKMY+N QLGKLEPH++A+ADVAY+ ML+++ NQCIVISGESGSG
Sbjct: 185  AINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSG 244

Query: 245  KTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNY 304
            KTQSTNFLIH LTALSQKG+ASGVE+ ILGAGPVLEAFGNAKTAHNNNSSRFGKFIQV+Y
Sbjct: 245  KTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSY 304

Query: 305  QETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYL 364
             E+G V GA VEKYLLEKSRLV QE +ERNYHVFYYLL G SE+ER  F LKQPE+Y YL
Sbjct: 305  LESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYL 364

Query: 365  NQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLS 424
            NQ   K                    +GEDL+HDFERL+ AMEMVGFLP T++QIF++LS
Sbjct: 365  NQHNLK------------------IEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLS 406

Query: 425  AILHLGNICYKKK-TYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLI 483
            AIL+LGN+ YKK+ T R++ +++  PEVL  +S+LL+VK E+L E L  RKTVTV +KLI
Sbjct: 407  AILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLI 466

Query: 484  LPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFED 543
            LPY L+EA+T R+SMAKSLYSALFDWIV RINHALLN KD+E     LSIGVLDIFGFED
Sbjct: 467  LPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFED 526

Query: 544  YENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKP 603
            +E NSFEQFCIN+ANE+LQ+YFNQHIFKLEQEEY+ EGI+WHNI Y DN  CI+LISKKP
Sbjct: 527  FERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKP 586

Query: 604  TGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKD 663
            TGL +LLDEESNFP AT+QTLL KFK QHEDN Y     VMEPAFII+H+AGKVKY +KD
Sbjct: 587  TGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKD 646

Query: 664  FREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNI 723
            FREKN D+MRPDIVALLR S ++++  +IG+DPVAVFRWA+LRA  RAM   REAG+   
Sbjct: 647  FREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRA 706

Query: 724  HRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQG 783
             R               M S     HP      E+ +        + R      +  ++G
Sbjct: 707  ER---------AEKAAGMSSPGAQSHPE-----ELPRGASTPSEKLYRDLHNQMIKSIKG 752

Query: 784  MNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGILTRN 843
                          + W G             SLL          S   L++    + ++
Sbjct: 753  --------------LPWQG---------EDPRSLLQ---------SLSRLQKPRAFILKS 780

Query: 844  KNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLME 903
            K  K K  +PK+LL+  SLK +  +TL DR TKSLLHLHKKKKPPSISAQFQ SL+KL+E
Sbjct: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840

Query: 904  TLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVS 963
             LG+AEP+F++CIRSNAEK  L F D LVL+QLRYTGMLETVRIR+SGYS+KY+FQDF  
Sbjct: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900

Query: 964  HFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRI 1023
             F VLLP++  P +  I     K+ ++  NYQ+GKT VFLKE ERQ LQ+ LH+EV+R+I
Sbjct: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960

Query: 1024 ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQA 1083
            +LLQ WFR++L R+HFL +++A+V IQ  WR+Y  ++          A     AA  LQA
Sbjct: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRR----------ALERTQAAVYLQA 1010

Query: 1084 SWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKII 1143
            SWR + +R+ Y   + + I +Q   R + +R+  + +           S++ + + K+  
Sbjct: 1011 SWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMI----------SEKQKAEEKERE 1060

Query: 1144 LLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNRI 1203
             L++   G     + +A   Q++ E  PE            E+Q SD S  E  S +   
Sbjct: 1061 ALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEA 1120

Query: 1204 KAIE-----------ECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLV 1252
             + E           E    + S+R  RES      E    Q +  QS      +E+  +
Sbjct: 1121 PSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQS-----CKEESAL 1175

Query: 1253 RERPRSLEDLHQKKVGRAKRESR 1275
            RE  R +       +   K+ESR
Sbjct: 1176 REPSRRVTQEQGVSLLEDKKESR 1198



 Score =  449 bits (1155), Expect = e-125
 Identities = 240/561 (42%), Positives = 362/561 (64%), Gaps = 34/561 (6%)

Query: 1823 KENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNED 1882
            K  KEP  K K+ R+VKI  + + S  W+    + I + ++LK +DEFLL K+NDL ++ 
Sbjct: 1471 KRTKEPGGKGKKNRNVKIGKITV-SEKWRESVFRQITNANELKYLDEFLLNKINDLRSQK 1529

Query: 1883 SKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGK-SIRYKDLYALFEQILEKTMRLEQ 1941
                T ++ +F +A ++FR NI + YS    + +GK  + YKDL   + QI+   +  E+
Sbjct: 1530 ----TPIESLFIEATEKFRSNIKTMYS----VPNGKIHVGYKDLMENY-QIVVSNLATER 1580

Query: 1942 RDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVEEHNGHI 2001
                G+    + +N F+  LDE+   +  +D    K  K ++KKR+++    V+EHNGH+
Sbjct: 1581 ----GQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERA--VQEHNGHV 1634

Query: 2002 FKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKY----DPELS 2057
            F + Q SIP  CE C S IW+MD+A +C +CK  CHKKC  K  + CS  Y    +P + 
Sbjct: 1635 FASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVE 1694

Query: 2058 SRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117
               FGV +  LTS+  +VP+V+EKL+ ++EMHGLYTEG+YRKSG+ N+ +ELRQ L TD 
Sbjct: 1695 PGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1754

Query: 2118 ESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQL 2177
             +V L+++ IH I  V KQWLR+LP PLMTF  Y +FLRA+ L E++E +  +Y+V++ L
Sbjct: 1755 AAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHL 1814

Query: 2178 SRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTT 2237
               + N+LERLIFHLV++AL ED NRMS  ALAI+FAPC+LRCPD +DPL S++D+ K T
Sbjct: 1815 PEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1874

Query: 2238 TCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVV 2297
            TCVE+++ EQM KYK ++++IS LE AE+ A  RLSL+R++     ++ G +  P   V+
Sbjct: 1875 TCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQN-APWPLKLG-FSSPYEGVL 1932

Query: 2298 VRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEER---VLTEQIENLQKEKEELTFEM 2354
             + P   D+ EE        E ++  +++AA   E+R   +L E+I+++++EKE++T+ +
Sbjct: 1933 NKSPKTRDIQEE--------ELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRL 1984

Query: 2355 LVLEPRASDDETLESEASIGT 2375
              L+PR SD+E L+SE S  T
Sbjct: 1985 PELDPRGSDEENLDSETSAST 2005


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  458 bits (1179), Expect = e-128
 Identities = 250/581 (43%), Positives = 356/581 (61%), Gaps = 29/581 (4%)

Query: 111  NLDGSIHYGSLQSWLRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRF 170
            +L GS       SW       R +    F  Q  +   +D+  L DL E T+L NL+ RF
Sbjct: 1187 SLRGSWEEVGPPSWRNKMHSIRNLPSMRFREQHGEDGVEDMTQLEDLQETTVLSNLKIRF 1246

Query: 171  KHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRK 230
            +   IYTY+GSIL+ +NP++   IY P+ V+ Y+   LG+  PH++AVA++A+  ML  K
Sbjct: 1247 ERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAK 1306

Query: 231  KNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGVEQI-ILGAGPVLEAFGNAKTAH 289
            +NQCI+ISGESGSGKT++T  ++ +L A++QK     ++QI IL A P+LE+FGNAKT  
Sbjct: 1307 QNQCIIISGESGSGKTEATKLILRYLAAMNQK--REVMQQIKILEATPLLESFGNAKTVR 1364

Query: 290  NNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDE 349
            N+NSSRFGKF+++ + E G + GA   +YLLEKSR+V+Q  NERNYH+FY LLAG     
Sbjct: 1365 NDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQL 1423

Query: 350  RSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMV 409
            R AF L++ E Y+YLNQ                   +C  + G+    DF RL  AME++
Sbjct: 1424 RQAFSLQEAETYYYLNQ-----------------GGNC-EIAGKSDADDFRRLLAAMEVL 1465

Query: 410  GFLPKTRRQIFSLLSAILHLGNICYKK-KTYRDDSIDICNPEVLPIVSELLEVKEEMLFE 468
            GF  + +  IF +L++ILHLGN+ ++K +T   +   + +   +  V+ELL++  E L +
Sbjct: 1466 GFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPEGLQK 1525

Query: 469  ALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNT 528
            A+  + T T+ EK+  P  +  AV  R+++AK LY+ LF W++ R+N  +   +D     
Sbjct: 1526 AITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPRQD----- 1580

Query: 529  KTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNID 588
             TLSI +LDI+GFED   NSFEQ CIN+ANE LQ+ FN+ +F+ EQEEY  E I W  I 
Sbjct: 1581 -TLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEIT 1639

Query: 589  YIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAF 648
            + DN  CINLIS KP G+L +LD++  FPQAT+ T L K  + H  N     P +  P F
Sbjct: 1640 FADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMPLPEF 1699

Query: 649  IIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFIS 689
             IKHYAGKV Y V  F +KN D +R D++ L   S+   ++
Sbjct: 1700 TIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740



 Score =  104 bits (259), Expect = 1e-21
 Identities = 65/217 (29%), Positives = 118/217 (54%), Gaps = 12/217 (5%)

Query: 886  KPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETV 945
            K  +++A+FQ SL  L+E + +  P F++C++ N +K P  F   +V+ QLRY+G+LETV
Sbjct: 1766 KAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETV 1825

Query: 946  RIRQSGYSSKYSFQDFVSHFHVLLP-RNIIPSKFN--IQDFFRKINLNPDNYQVGKTMVF 1002
            RIR+ G+  +  FQ F+  +  L+  ++ +P+  +  +    R   + P+ Y+VG + +F
Sbjct: 1826 RIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVMPNMYRVGVSKLF 1885

Query: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQV 1062
            LKE   Q L+ +    +    + LQR  R    ++ F  LR   +++Q   R YL +++ 
Sbjct: 1886 LKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGYLARQRY 1945

Query: 1063 RDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRA 1099
            +          M  +    ++   A++ R+RYL+LRA
Sbjct: 1946 QQ---------MRRSLVKFRSLVHAYVSRRRYLKLRA 1973



 Score = 40.4 bits (93), Expect = 0.023
 Identities = 18/52 (34%), Positives = 34/52 (65%)

Query: 1116 HMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLR 1167
            ++AA+ +Q   + +   +R++  R KIILLQS  RG+ ARQR++ ++   ++
Sbjct: 1903 NLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVK 1954



 Score = 39.3 bits (90), Expect = 0.050
 Identities = 21/81 (25%), Positives = 43/81 (53%), Gaps = 5/81 (6%)

Query: 1089 LERQRYLELRAAAIVIQQKWRDYYRRRHMAA-----ICIQARWKAYRESKRYQEQRKKII 1143
            LE  R   L  AA+ +Q+  R ++ +R   +     I +Q+R + Y   +RYQ+ R+ ++
Sbjct: 1894 LESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLV 1953

Query: 1144 LLQSTCRGFRARQRFKALKEQ 1164
              +S    + +R+R+  L+ +
Sbjct: 1954 KFRSLVHAYVSRRRYLKLRAE 1974


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  442 bits (1136), Expect = e-123
 Identities = 232/549 (42%), Positives = 339/549 (61%), Gaps = 22/549 (4%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           +D+  L DLNE  +L NL  R++   IYTY GSIL+ +NP++ L IY+P++++ Y N ++
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268
           G++ PHI+A+AD  Y  M +  ++QC +ISGESG+GKT+ST  ++  L A+S  G  S +
Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           EQ +L A P+LEAFGNAKT  N+NSSRFGK+I +++ + G + GA +E+YLLEKSR+  Q
Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCF 388
             +ERNYHVFY +L G SED++    L Q  +Y+YL                  +  +C 
Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYL------------------AMGNCI 287

Query: 389 TVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD-DSIDIC 447
           T EG     ++  ++ AM+++ F      +I  LL+AILHLGN+ Y+ +T+ + D+ ++ 
Sbjct: 288 TCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVL 347

Query: 448 NPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALF 507
               L   + LLEV    L   L +R  +T GE +  P    +A+ VR++  K +Y  LF
Sbjct: 348 FSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLF 407

Query: 508 DWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQ 567
            WIV +IN A+      +      SIG+LDIFGFE++  NSFEQ CINFANE LQ +F +
Sbjct: 408 VWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVR 467

Query: 568 HIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDK 627
           H+FKLEQEEY  E I W +I++ DN   +++I+ KP  ++ L+DEES FP+ T+ T+L K
Sbjct: 468 HVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHK 527

Query: 628 FKHQHEDN-SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNA 686
              QH+ N +YI      E  F I H+AG V Y  + F EKN D +  DI+ L+ SS+N 
Sbjct: 528 LNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587

Query: 687 FISGMIGID 695
           FI  +   D
Sbjct: 588 FIKQIFQAD 596



 Score =  152 bits (385), Expect = 3e-36
 Identities = 125/458 (27%), Positives = 208/458 (45%), Gaps = 85/458 (18%)

Query: 884  KKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLE 943
            +K+ P++S+QF+ SL  LM TLG  +P+FV+CI+ N  K P+ F   L +RQLRY+GM+E
Sbjct: 604  RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663

Query: 944  TVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPS------KFNIQDFFRKINLNPDNYQVG 997
            T+RIR++GY  +YSF +FV  + VLLP  + P+      +   Q     +    D++Q+G
Sbjct: 664  TIRIRRAGYPIRYSFVEFVERYRVLLP-GVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722

Query: 998  KTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYL 1057
            KT +FLK+     L+    + +  R+ILLQ+  R    R +FL L+ A+ +IQR WR + 
Sbjct: 723  KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH- 781

Query: 1058 NQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHM 1117
                                      + R +    R   LR  A+   +K    YR    
Sbjct: 782  --------------------------NCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQ 815

Query: 1118 AAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVN 1177
              I  QAR +AY   K ++ +   ++ +Q+  RG  AR+  + L+ + L           
Sbjct: 816  RIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYL----------- 864

Query: 1178 IKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLK-ESPNKQQE 1236
                            W       R++A  E   + E  ++ +E S    K E+  K QE
Sbjct: 865  ----------------W-------RLEA--EKMRLAEEEKLRKEMSAKKAKEEAERKHQE 899

Query: 1237 RAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLG 1296
            R    +  D + ++  +E  R  ++L  +++ RA+ E     ++   +F      + + G
Sbjct: 900  RLAQLAREDAERELKEKEAARRKKEL-LEQMERARHEPVNHSDMVDKMFGF----LGTSG 954

Query: 1297 GISPSEDR---------RWSTELVPEGLQSPRGTPDSE 1325
            G+   E +         R   E+V E L +    PD +
Sbjct: 955  GLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDED 992


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  442 bits (1136), Expect = e-123
 Identities = 232/549 (42%), Positives = 339/549 (61%), Gaps = 22/549 (4%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           +D+  L DLNE  +L NL  R++   IYTY GSIL+ +NP++ L IY+P++++ Y N ++
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268
           G++ PHI+A+AD  Y  M +  ++QC +ISGESG+GKT+ST  ++  L A+S  G  S +
Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           EQ +L A P+LEAFGNAKT  N+NSSRFGK+I +++ + G + GA +E+YLLEKSR+  Q
Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCF 388
             +ERNYHVFY +L G SED++    L Q  +Y+YL                  +  +C 
Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYL------------------AMGNCI 287

Query: 389 TVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD-DSIDIC 447
           T EG     ++  ++ AM+++ F      +I  LL+AILHLGN+ Y+ +T+ + D+ ++ 
Sbjct: 288 TCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVL 347

Query: 448 NPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALF 507
               L   + LLEV    L   L +R  +T GE +  P    +A+ VR++  K +Y  LF
Sbjct: 348 FSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLF 407

Query: 508 DWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQ 567
            WIV +IN A+      +      SIG+LDIFGFE++  NSFEQ CINFANE LQ +F +
Sbjct: 408 VWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVR 467

Query: 568 HIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDK 627
           H+FKLEQEEY  E I W +I++ DN   +++I+ KP  ++ L+DEES FP+ T+ T+L K
Sbjct: 468 HVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHK 527

Query: 628 FKHQHEDN-SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNA 686
              QH+ N +YI      E  F I H+AG V Y  + F EKN D +  DI+ L+ SS+N 
Sbjct: 528 LNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587

Query: 687 FISGMIGID 695
           FI  +   D
Sbjct: 588 FIKQIFQAD 596



 Score =  152 bits (385), Expect = 3e-36
 Identities = 125/458 (27%), Positives = 208/458 (45%), Gaps = 85/458 (18%)

Query: 884  KKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLE 943
            +K+ P++S+QF+ SL  LM TLG  +P+FV+CI+ N  K P+ F   L +RQLRY+GM+E
Sbjct: 604  RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663

Query: 944  TVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPS------KFNIQDFFRKINLNPDNYQVG 997
            T+RIR++GY  +YSF +FV  + VLLP  + P+      +   Q     +    D++Q+G
Sbjct: 664  TIRIRRAGYPIRYSFVEFVERYRVLLP-GVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722

Query: 998  KTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYL 1057
            KT +FLK+     L+    + +  R+ILLQ+  R    R +FL L+ A+ +IQR WR + 
Sbjct: 723  KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH- 781

Query: 1058 NQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHM 1117
                                      + R +    R   LR  A+   +K    YR    
Sbjct: 782  --------------------------NCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQ 815

Query: 1118 AAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVN 1177
              I  QAR +AY   K ++ +   ++ +Q+  RG  AR+  + L+ + L           
Sbjct: 816  RIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYL----------- 864

Query: 1178 IKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLK-ESPNKQQE 1236
                            W       R++A  E   + E  ++ +E S    K E+  K QE
Sbjct: 865  ----------------W-------RLEA--EKMRLAEEEKLRKEMSAKKAKEEAERKHQE 899

Query: 1237 RAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLG 1296
            R    +  D + ++  +E  R  ++L  +++ RA+ E     ++   +F      + + G
Sbjct: 900  RLAQLAREDAERELKEKEAARRKKEL-LEQMERARHEPVNHSDMVDKMFGF----LGTSG 954

Query: 1297 GISPSEDR---------RWSTELVPEGLQSPRGTPDSE 1325
            G+   E +         R   E+V E L +    PD +
Sbjct: 955  GLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDED 992


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  442 bits (1136), Expect = e-123
 Identities = 232/549 (42%), Positives = 339/549 (61%), Gaps = 22/549 (4%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           +D+  L DLNE  +L NL  R++   IYTY GSIL+ +NP++ L IY+P++++ Y N ++
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268
           G++ PHI+A+AD  Y  M +  ++QC +ISGESG+GKT+ST  ++  L A+S  G  S +
Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           EQ +L A P+LEAFGNAKT  N+NSSRFGK+I +++ + G + GA +E+YLLEKSR+  Q
Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCF 388
             +ERNYHVFY +L G SED++    L Q  +Y+YL                  +  +C 
Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYL------------------AMGNCI 287

Query: 389 TVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD-DSIDIC 447
           T EG     ++  ++ AM+++ F      +I  LL+AILHLGN+ Y+ +T+ + D+ ++ 
Sbjct: 288 TCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVL 347

Query: 448 NPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALF 507
               L   + LLEV    L   L +R  +T GE +  P    +A+ VR++  K +Y  LF
Sbjct: 348 FSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLF 407

Query: 508 DWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQ 567
            WIV +IN A+      +      SIG+LDIFGFE++  NSFEQ CINFANE LQ +F +
Sbjct: 408 VWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVR 467

Query: 568 HIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDK 627
           H+FKLEQEEY  E I W +I++ DN   +++I+ KP  ++ L+DEES FP+ T+ T+L K
Sbjct: 468 HVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHK 527

Query: 628 FKHQHEDN-SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNA 686
              QH+ N +YI      E  F I H+AG V Y  + F EKN D +  DI+ L+ SS+N 
Sbjct: 528 LNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587

Query: 687 FISGMIGID 695
           FI  +   D
Sbjct: 588 FIKQIFQAD 596



 Score =  152 bits (385), Expect = 3e-36
 Identities = 125/458 (27%), Positives = 208/458 (45%), Gaps = 85/458 (18%)

Query: 884  KKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLE 943
            +K+ P++S+QF+ SL  LM TLG  +P+FV+CI+ N  K P+ F   L +RQLRY+GM+E
Sbjct: 604  RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663

Query: 944  TVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPS------KFNIQDFFRKINLNPDNYQVG 997
            T+RIR++GY  +YSF +FV  + VLLP  + P+      +   Q     +    D++Q+G
Sbjct: 664  TIRIRRAGYPIRYSFVEFVERYRVLLP-GVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722

Query: 998  KTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYL 1057
            KT +FLK+     L+    + +  R+ILLQ+  R    R +FL L+ A+ +IQR WR + 
Sbjct: 723  KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH- 781

Query: 1058 NQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHM 1117
                                      + R +    R   LR  A+   +K    YR    
Sbjct: 782  --------------------------NCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQ 815

Query: 1118 AAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVN 1177
              I  QAR +AY   K ++ +   ++ +Q+  RG  AR+  + L+ + L           
Sbjct: 816  RIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYL----------- 864

Query: 1178 IKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLK-ESPNKQQE 1236
                            W       R++A  E   + E  ++ +E S    K E+  K QE
Sbjct: 865  ----------------W-------RLEA--EKMRLAEEEKLRKEMSAKKAKEEAERKHQE 899

Query: 1237 RAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLG 1296
            R    +  D + ++  +E  R  ++L  +++ RA+ E     ++   +F      + + G
Sbjct: 900  RLAQLAREDAERELKEKEAARRKKEL-LEQMERARHEPVNHSDMVDKMFGF----LGTSG 954

Query: 1297 GISPSEDR---------RWSTELVPEGLQSPRGTPDSE 1325
            G+   E +         R   E+V E L +    PD +
Sbjct: 955  GLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDED 992


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  439 bits (1129), Expect = e-122
 Identities = 225/549 (40%), Positives = 338/549 (61%), Gaps = 22/549 (4%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           DD+  L DLNE  ++ NL  R++  KIYTY GSIL+ +NPF+ LP+Y  + V++Y +  +
Sbjct: 68  DDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHM 127

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268
           G+L PH++A+A+  Y +M + K++QC +ISGESG+GKT++T  ++  L  +S  G  S +
Sbjct: 128 GELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS--GQHSWI 185

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           EQ +L A P+LEAFGNAKT  N+NSSRFGK+I + +  +G + GA +E++LLEKSR+  Q
Sbjct: 186 EQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQ 245

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCF 388
              ERNYH+FY +L G S +++    L  P EYHYL                     +C 
Sbjct: 246 APEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTM------------------GNCT 287

Query: 389 TVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD-DSIDIC 447
           + EG +   D+  ++ AM+++ F       +  LL+AILHLGN+ +    + + D+ D+ 
Sbjct: 288 SCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVM 347

Query: 448 NPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALF 507
                P V +LLEV+ + L + L+    +  GE +     +A+A   R++  K +Y  LF
Sbjct: 348 ETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLF 407

Query: 508 DWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQ 567
            WIV +IN A+      +      +IG+LDIFGFE++ENNSFEQ CINFANE LQ +F Q
Sbjct: 408 LWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQ 467

Query: 568 HIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDK 627
           H+F +EQEEYR+E ISW  I Y DN   ++L++ KP  ++ LLDEES FPQ T+ T+L K
Sbjct: 468 HVFTMEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQK 527

Query: 628 FKHQHEDN-SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNA 686
               H +N ++++   + +  F I H+AG+V Y  + F EKN D +  DI+ L+ SSKN 
Sbjct: 528 LNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNK 587

Query: 687 FISGMIGID 695
           F+  +  ++
Sbjct: 588 FLREIFNLE 596



 Score =  142 bits (357), Expect = 5e-33
 Identities = 100/349 (28%), Positives = 168/349 (48%), Gaps = 51/349 (14%)

Query: 835  RAHGILTRNKNFKSKPALPKHLLEVNS-LKHLTRLTLQD--------RITKSLLHLHKK- 884
            +A G L +N++  S   L       N  L+ +  L L +        R  K+  HL K  
Sbjct: 561  QAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSA 620

Query: 885  ---KKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGM 941
               K+P ++ +QF+ SL +LM+ L   +PYF++CI+ N  K PL F   L LRQLRY+GM
Sbjct: 621  DSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGM 680

Query: 942  LETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINL--------NPDN 993
            +ETV IR+SG+  +Y+F++F   F VLLP  +   +  +Q   R++ L           +
Sbjct: 681  METVHIRKSGFPIRYTFEEFSQRFGVLLPNAM---RMQLQGKLRQMTLGITDVWLRTDKD 737

Query: 994  YQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFW 1053
            ++ GKT +FL++ +   L+    Q + R  + +Q+  R    R+ FL  R+A+V +Q +W
Sbjct: 738  WKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWW 797

Query: 1054 RNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYR 1113
            R Y N++  +   V  +                           R  AI   Q     Y+
Sbjct: 798  RGYCNRRNFKLILVGFE---------------------------RLQAIARSQPLARQYQ 830

Query: 1114 RRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALK 1162
                  + +QA  + Y   ++ Q +R+ ++++Q+  RG  AR+ F+  K
Sbjct: 831  AMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRK 879


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  438 bits (1127), Expect = e-122
 Identities = 237/552 (42%), Positives = 344/552 (62%), Gaps = 37/552 (6%)

Query: 145 QKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLP-IYNPKYVKMY 203
           ++  DD+ SL +L+  +++ NL  R+K  +IYTY+GSIL  +NP++ +  +Y P  ++ Y
Sbjct: 62  EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121

Query: 204 DNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKG 263
               LG+L PHI+A+A+  Y  + +R  NQCI+ISGESG+GKT+ST  ++  L+ +SQ+ 
Sbjct: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181

Query: 264 F-------ASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVE 316
                    S VE+ IL + P++EAFGNAKT +NNNSSRFGKF+Q+N  + G + G  + 
Sbjct: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241

Query: 317 KYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSW 376
            YLLEK+R+V Q   ERNYH+FY LLAG   +ER  F+L  PE YHYLNQ          
Sbjct: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQ---------- 291

Query: 377 DDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKK 436
              C + +    T+  ++    F  +  AM+++ F  +  R++  LL+ ILHLGNI    
Sbjct: 292 -SGCVEDK----TISDQE---SFREVITAMDVMQFSKEEVREVSRLLAGILHLGNI---- 339

Query: 437 KTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRN 496
           +        +     L   +ELL +    L +AL  R     GE+++ P  + +AV  R+
Sbjct: 340 EFITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRD 399

Query: 497 SMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINF 556
           S+A +LY+  F+W++ +IN  +  ++D +      SIG+LDIFGFE++E N FEQF IN+
Sbjct: 400 SLAMALYACCFEWVIKKINSRIKGNEDFK------SIGILDIFGFENFEVNHFEQFNINY 453

Query: 557 ANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNF 616
           ANE+LQ YFN+HIF LEQ EY  EG+ W +ID+IDN  C++LI KK  GLL L++EES+F
Sbjct: 454 ANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKK-LGLLALINEESHF 512

Query: 617 PQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDI 676
           PQAT+ TLL+K   QH +N +   P V    F +KHYAG+V+Y V+   EKN D  R D+
Sbjct: 513 PQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDL 572

Query: 677 VALLRSSKNAFI 688
           + LLR S+  FI
Sbjct: 573 LNLLRESRFDFI 584



 Score =  145 bits (367), Expect = 4e-34
 Identities = 162/685 (23%), Positives = 290/685 (42%), Gaps = 124/685 (18%)

Query: 816  SLLDKDGIFANSTSSKLLERAHGILTRNKNFKSKPALP------KHLL-----EVNSLKH 864
            +L++++  F  +T S LLE+ H     N +F  KP +       KH       +V  +  
Sbjct: 504  ALINEESHFPQATDSTLLEKLHS-QHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILE 562

Query: 865  LTRLTLQD-----------------------RITKSLLHLHKKKKPPSISAQFQASLSKL 901
              R T +D                       R  +  L    K + P++S+QF+ SL  L
Sbjct: 563  KNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSL 622

Query: 902  METLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDF 961
            M TL  + P+FV+CI+ N +K+P +F   +VL QLRY+GMLETVRIR++GY+ +  FQDF
Sbjct: 623  MATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDF 682

Query: 962  VSHFHVLLPRNIIPS--KFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEV 1019
               + VL+    +P   +       +  + +   +Q+GKT VFL+E   Q L+    +EV
Sbjct: 683  YKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEV 742

Query: 1020 LRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAA 1079
                ++++      L R+ +  +    VIIQ+ +R +L ++                   
Sbjct: 743  SHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRR------------------- 783

Query: 1080 LLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRE---SKRYQ 1136
                         R+L L+ AAIV Q++ R    RR             YR+    KR Q
Sbjct: 784  -------------RFLHLKKAAIVFQKQLRGQIARR------------VYRQLLAEKREQ 818

Query: 1137 EQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWED 1196
            E++KK    +   R    R+R +  +E  LR  + E      +     E++    S  ++
Sbjct: 819  EEKKKQEEEEKKKREEEERERERERREAELRAQQEE------ETRKQQELEALQKS-QKE 871

Query: 1197 CSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERP 1256
                  ++  +E K V E  R+ +E     +++    ++++  S +   LQ+  L   R 
Sbjct: 872  AELTRELEKQKENKQVEEILRLEKE-----IEDLQRMKEQQELSLTEASLQK--LQERRD 924

Query: 1257 RSLEDLHQKKVGRAKR--ESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEG 1314
            + L  L ++    A+   ES    E+++ + ++E    RSL     S    +S+EL    
Sbjct: 925  QELRRLEEEACRAAQEFLESLNFDEIDECVRNIE----RSL-----SVGSEFSSELAESA 975

Query: 1315 LQSPRGTPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNAL 1374
             +     P+   SQ       Y E +   ++     + D    SP  S     D R + +
Sbjct: 976  CEE---KPNFNFSQ------PYPEEE---VDEGFEADDDAFKDSPNPSEHGHSDQRTSGI 1023

Query: 1375 SASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDS---FISNSLPTFFYIPQQDPLKT 1431
              S+++S  +   + T+      +  ++   P ++DS     S+S  + + +PQ      
Sbjct: 1024 RTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGDLP 1083

Query: 1432 NSQLDTSIQRNKLLENEDTAGEALT 1456
            +   D    ++   +   T+G ++T
Sbjct: 1084 SPDGDYDYDQDDYEDGAITSGSSVT 1108



 Score = 33.9 bits (76), Expect = 2.1
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 6/95 (6%)

Query: 2314 EAAMETDITEQQQAAMQQEERVLTEQIENLQ--KEKEELTFEMLVL----EPRASDDETL 2367
            EA +  ++ +Q++    +E   L ++IE+LQ  KE++EL+     L    E R  +   L
Sbjct: 871  EAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRL 930

Query: 2368 ESEASIGTADSSENLNMESEYAISEKSERSLALSS 2402
            E EA     +  E+LN +         ERSL++ S
Sbjct: 931  EEEACRAAQEFLESLNFDEIDECVRNIERSLSVGS 965


>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
          Length = 1314

 Score =  415 bits (1067), Expect = e-115
 Identities = 229/552 (41%), Positives = 333/552 (60%), Gaps = 25/552 (4%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           DDL +L  L+E T++  L+ R+    IYTYVG ILI +NPF+ L IY+P++ ++Y   + 
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268
               PHI+A AD AY  M+   K+QCIVISGESGSGKT+S + ++ HLT L  K     +
Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
            + IL    ++EAFGN+ TA N+NSSRFGK++++ +  TG V+GA + +YLLEKSR++ Q
Sbjct: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524

Query: 329 EHNERNYHVFYYLLAGASEDER-SAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
              E+N+H+FYY+ AG    ++ S F L + +   Y+   T + +               
Sbjct: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHD------------- 571

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYK--KKTYRDDSID 445
                E  R  FE +Q    ++GF  K    ++ +L+ IL++GNI +      ++ D  +
Sbjct: 572 -ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSE 630

Query: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
           + N E L   + +L +  E L EAL +   VT GE +I    +  A  VR++M+K+LY  
Sbjct: 631 VPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGR 690

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF WIV RIN  L   +++      +++G+LDIFGFE+++ NSFEQ CIN ANE++Q+YF
Sbjct: 691 LFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYF 750

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLL 625
           NQH+F LEQ EY+ EGI    ++Y DN   +++  +KP GLL LLDEES FPQAT+QTL+
Sbjct: 751 NQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLV 810

Query: 626 DKFKHQHEDN---SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRS 682
           DKF    EDN    Y   P  +E  F I+HYAGKV Y      EKN D +  D+V +LR+
Sbjct: 811 DKF----EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRT 866

Query: 683 SKNAFISGMIGI 694
           S+N  +  +  I
Sbjct: 867 SENMLLQQLFSI 878



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 56/162 (34%), Positives = 96/162 (59%), Gaps = 6/162 (3%)

Query: 886  KPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETV 945
            K  ++++ F+ SL  L+  +   +P+FV+CI+ N ++  L+FS   VL QLR TG+LETV
Sbjct: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986

Query: 946  RIRQSGYSSKYSFQDFVSHFHVL---LPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVF 1002
             IR+ GYS +  F++FV  ++ L     +  + SK +      K  L  D++ +GKT VF
Sbjct: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRL--DHWVLGKTKVF 1044

Query: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQ 1044
            LK    + L +LL +EV+ R+++LQ + +  L  + +  +R+
Sbjct: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVRE 1085


>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
          Length = 1341

 Score =  415 bits (1067), Expect = e-115
 Identities = 229/552 (41%), Positives = 333/552 (60%), Gaps = 25/552 (4%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           DDL +L  L+E T++  L+ R+    IYTYVG ILI +NPF+ L IY+P++ ++Y   + 
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268
               PHI+A AD AY  M+   K+QCIVISGESGSGKT+S + ++ HLT L  K     +
Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
            + IL    ++EAFGN+ TA N+NSSRFGK++++ +  TG V+GA + +YLLEKSR++ Q
Sbjct: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524

Query: 329 EHNERNYHVFYYLLAGASEDER-SAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
              E+N+H+FYY+ AG    ++ S F L + +   Y+   T + +               
Sbjct: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHD------------- 571

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYK--KKTYRDDSID 445
                E  R  FE +Q    ++GF  K    ++ +L+ IL++GNI +      ++ D  +
Sbjct: 572 -ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSE 630

Query: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
           + N E L   + +L +  E L EAL +   VT GE +I    +  A  VR++M+K+LY  
Sbjct: 631 VPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGR 690

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF WIV RIN  L   +++      +++G+LDIFGFE+++ NSFEQ CIN ANE++Q+YF
Sbjct: 691 LFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYF 750

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLL 625
           NQH+F LEQ EY+ EGI    ++Y DN   +++  +KP GLL LLDEES FPQAT+QTL+
Sbjct: 751 NQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLV 810

Query: 626 DKFKHQHEDN---SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRS 682
           DKF    EDN    Y   P  +E  F I+HYAGKV Y      EKN D +  D+V +LR+
Sbjct: 811 DKF----EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRT 866

Query: 683 SKNAFISGMIGI 694
           S+N  +  +  I
Sbjct: 867 SENMLLQQLFSI 878



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 61/178 (34%), Positives = 103/178 (57%), Gaps = 10/178 (5%)

Query: 886  KPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETV 945
            K  ++++ F+ SL  L+  +   +P+FV+CI+ N ++  L+FS   VL QLR TG+LETV
Sbjct: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986

Query: 946  RIRQSGYSSKYSFQDFVSHFHVL---LPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVF 1002
             IR+ GYS +  F++FV  ++ L     +  + SK +      K  L  D++ +GKT VF
Sbjct: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRL--DHWVLGKTKVF 1044

Query: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQ----ASVIIQRFWRNY 1056
            LK    + L +LL +EV+ R+++LQ + +  L  + +  +R+     ++ IQ  WR Y
Sbjct: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQSAWRGY 1101



 Score = 33.9 bits (76), Expect = 2.1
 Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 4/50 (8%)

Query: 1120 ICIQARWKAYRESKRYQEQRKK----IILLQSTCRGFRARQRFKALKEQR 1165
            + +QA  K +  ++RY++ R+K     I +QS  RG+ AR++FK +  +R
Sbjct: 1065 VVLQAYTKGWLGARRYKKVREKREKGAIAIQSAWRGYDARRKFKKISNRR 1114


>gi|145275208 myosin IIIA [Homo sapiens]
          Length = 1616

 Score =  412 bits (1058), Expect = e-114
 Identities = 228/549 (41%), Positives = 338/549 (61%), Gaps = 17/549 (3%)

Query: 146 KDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDN 205
           KD DDL +L  L+E T+ E L   +  ++IY YVG ILI +NPF+ L +Y+ K+ K+Y  
Sbjct: 338 KDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIG 397

Query: 206 HQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFA 265
            +     PHI+A+AD+ Y +M+    +QCIVISGESG+GKT++ + L+  LT L +    
Sbjct: 398 SKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR 457

Query: 266 SGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRL 325
           + +++ IL    ++EAFGNA T  N+NSSRFGK++++ +  +G V+GA + +YLLEKSR+
Sbjct: 458 T-LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRV 516

Query: 326 VYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEP 385
           ++Q   E+N+H+FYY+ AG +E ++ A H K PE          KP R   +D+    + 
Sbjct: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLA-HYKLPEN---------KPPRYLQNDHLRTVQD 566

Query: 386 DCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKT--YRDDS 443
               +     +  +E ++   +++GF  +    I+S+L+AIL++GNI +      ++ D 
Sbjct: 567 ---IMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDK 623

Query: 444 IDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLY 503
             I N   L   + LL ++ + L EAL +   VT GE +I P  + +A  VR++MAK+LY
Sbjct: 624 SHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLY 683

Query: 504 SALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQH 563
             LF WIV  IN  L +      N   LSIG+LDIFGFE+++ NSFEQ CIN ANE++Q+
Sbjct: 684 GRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQY 743

Query: 564 YFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQT 623
           Y+NQH+F  EQ EY  E +    I+Y DN   +++  +KP GLL LLDEES FP+AT+QT
Sbjct: 744 YYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQT 803

Query: 624 LLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSS 683
           L++KF+   + + Y   P  ME +F I HYAGKV Y    F  KN D +  DIV LLRSS
Sbjct: 804 LVEKFEGNLK-SQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSS 862

Query: 684 KNAFISGMI 692
            N+ I  ++
Sbjct: 863 DNSVIRQLV 871



 Score =  102 bits (255), Expect = 4e-21
 Identities = 62/215 (28%), Positives = 118/215 (54%), Gaps = 10/215 (4%)

Query: 886  KPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETV 945
            K  ++++ F+ SL  L+  +   +P+FV+CI+ N+E+   ++    VL QLRYTG+LET 
Sbjct: 922  KTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETA 981

Query: 946  RIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFN---IQDFFRKINLNPDNYQVGKTMVF 1002
            RIR+ G+S +  F +F+  +++L  ++    + +         K  L  DN+ +GKT VF
Sbjct: 982  RIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGL--DNWALGKTKVF 1039

Query: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHL----RQASVIIQRFWRNYLN 1058
            LK    + L +L+ +E + ++IL+Q   R  LC + +  +    +++++IIQ   R +L 
Sbjct: 1040 LKYYHVEQL-NLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLV 1098

Query: 1059 QKQVRDAAVQKDAFVMASAAALLQASWRAHLERQR 1093
            +KQ ++    K+  V     +  +  ++ + E  R
Sbjct: 1099 RKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTR 1133



 Score = 33.5 bits (75), Expect = 2.8
 Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 29/159 (18%)

Query: 1120 ICIQARWKAYRESKRYQ---EQRKK-IILLQSTCRGFRARQRFKALKEQRLRETKPEVGL 1175
            I IQA  +A+  S+RYQ   E+RK+  I++QS  RG   R++ K               +
Sbjct: 1060 ILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKE--------------I 1105

Query: 1176 VNIKGYGSLEIQGSDPSGWEDCSFDNRIKAI--EECKSVIESNR-----ISRESSVDCLK 1228
            V++K      IQ SD       +F+N  ++   ++ ++ I +N       + + SV  +K
Sbjct: 1106 VDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISAPNNKGSVSVVK 1165

Query: 1229 ESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKV 1267
             S  K +E   +     ++ +  V + P+ + ++++++V
Sbjct: 1166 TSTFKPEEETTNA----VESNNRVYQTPKKMNNVYEEEV 1200


>gi|92859701 myosin VI [Homo sapiens]
          Length = 1285

 Score =  398 bits (1023), Expect = e-110
 Identities = 221/573 (38%), Positives = 337/573 (58%), Gaps = 34/573 (5%)

Query: 142 QPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLP-IYNPKYV 200
           +  +KD +D CSL  LNE TLL N++ R+  ++IYTYV +ILI +NP+  +P IY+ + +
Sbjct: 53  EDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAI 112

Query: 201 KMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALS 260
           K Y    LG   PH++A+AD A+  M   K +Q I++SGESG+GKT++T F++ +LT   
Sbjct: 113 KSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT--E 170

Query: 261 QKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLL 320
             G    ++  I+ A P+LEAFGNAKT  NNNSSRFGKF+++++ E  +V+G +V  YLL
Sbjct: 171 SYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLL 230

Query: 321 EKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQ-ITKKPLRQSWDDY 379
           EKSR+  Q   ERNYH+FY L AGASED R   HL  P+ + YLN+  T+    +  D  
Sbjct: 231 EKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQ 290

Query: 380 CYDSEPDCFTVEGEDLRH-------DFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNI 432
              +      ++   ++        DF R+  AM+ +G   + +  +F +++ +LHLGNI
Sbjct: 291 ILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNI 350

Query: 433 CYKKKTYRDDSIDICN--PEVLPIVSELLEVKEEMLFEALVTRKTVTV-----GEKLILP 485
            +++        ++ N   + L   +ELL + ++ L  +L TR  +T      G  + +P
Sbjct: 351 DFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVP 410

Query: 486 YKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYE 545
            K+ +A   R+++AK++YS LFD +V R+N            T +  IGVLDI GFE +E
Sbjct: 411 LKVEQANNARDALAKTVYSHLFDHVVNRVNQC------FPFETSSYFIGVLDIAGFEYFE 464

Query: 546 NNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTG 605
           +NSFEQFCIN+ NE+LQ +FN+ I K EQE Y+ EG+  + + Y+DN  CI+LI  K  G
Sbjct: 465 HNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVG 524

Query: 606 LLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPA----------FIIKHYAG 655
           +L +LDEE+  PQ ++Q        +H+D+  +  P   + A          FII+H+AG
Sbjct: 525 ILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAG 584

Query: 656 KVKYGVKDFREKNTDHMRPDIVALLRSSKNAFI 688
            V Y    F EKN D +   + +L+  S++ FI
Sbjct: 585 AVCYETTQFVEKNNDALHMSLESLICESRDKFI 617



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 37/166 (22%), Positives = 79/166 (47%), Gaps = 11/166 (6%)

Query: 889  SISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIR 948
            S+  +F+  L+ L++ L      F++CI+ N +     F    +L QL+ +GM+  + + 
Sbjct: 642  SVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLM 701

Query: 949  QSGYSSKYSFQDFVSHFHVLLPRNI--IPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQ 1006
            Q GY S+ SF +  + +   +P  +  +  +   +  F+ + LN ++Y+ G T VF +  
Sbjct: 702  QGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPG 761

Query: 1007 ERQHLQDLLHQ------EVLRRI---ILLQRWFRVLLCRQHFLHLR 1043
            +      ++        E+++R+   +   RW +V  C    + L+
Sbjct: 762  KFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLK 807


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  391 bits (1005), Expect = e-108
 Identities = 224/568 (39%), Positives = 326/568 (57%), Gaps = 33/568 (5%)

Query: 135 MERGFLPQPQQKDF----DDLCSLPDLNEKTLLENLRNRF-KHEKIYTYVGSILIVINPF 189
           ++R  LP  +  D     +DL +L  L+E  +L NL+ RF +   IYTY G +L+ INP+
Sbjct: 54  VQRNQLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPY 113

Query: 190 KFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQST 249
           + LPIY    +  Y    +G ++PHI+AVA+ AY  M + +KNQ I++SGESG+GKT S 
Sbjct: 114 EQLPIYGQDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSA 173

Query: 250 NFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGT 309
            + + +   +      + +E+ +L + P++EA GNAKT  N+NSSRFGK+IQ+ + +   
Sbjct: 174 KYAMRYFATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYH 233

Query: 310 VLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITK 369
           ++GA +  YLLEKSR+V+Q  +ERNYH+FY L A A   E     L   E          
Sbjct: 234 IIGANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE---------- 283

Query: 370 KPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHL 429
                   D+ Y S+    ++EG D   DFE+ + A  ++G     +  IF ++++ILHL
Sbjct: 284 --------DFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHL 335

Query: 430 GNICYKKKTYRD-DSIDICNPEV-LPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYK 487
           G++  + +  RD DS  I   +V L     LL V+   +   L  RK VT  E  +    
Sbjct: 336 GSVAIQAE--RDGDSCSISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMS 393

Query: 488 LAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENN 547
           L + +  RN++AK +Y+ LF WIV  IN AL  S   +H+     IGVLDI+GFE +E N
Sbjct: 394 LQQVINARNALAKHIYAQLFGWIVEHINKALHTSLK-QHS----FIGVLDIYGFETFEVN 448

Query: 548 SFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLL 607
           SFEQFCIN+ANE+LQ  FN H+FKLEQEEY  E I W  ID+ DN  CI+LI  K  G+L
Sbjct: 449 SFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAK-LGIL 507

Query: 608 HLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREK 667
            LLDEE   P+ T+Q    K   +H  + + + P +   AFII H+A KV+Y    F EK
Sbjct: 508 DLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRMSNTAFIIVHFADKVEYLSDGFLEK 567

Query: 668 NTDHMRPDIVALLRSSKNAFISGMIGID 695
           N D +  + + +L++SK   ++ +   D
Sbjct: 568 NRDTVYEEQINILKASKFPLVADLFHDD 595



 Score =  141 bits (355), Expect = 9e-33
 Identities = 186/763 (24%), Positives = 319/763 (41%), Gaps = 88/763 (11%)

Query: 873  RITKSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLV 932
            R  +  + +  K+   ++  QF+ SL  LMETL    P++V+CI+ N EKLP  F     
Sbjct: 615  RSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRA 674

Query: 933  LRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPS---KFNIQDFFRKINL 989
            ++QLR  G+LET+RI  +GY S++++ DF + + VL+ +  + +   K   +     +  
Sbjct: 675  VQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIK 734

Query: 990  NPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVII 1049
            +PD +Q G+T +F +  +  +L+ L   +     I++Q+  R  L +  +  L+ A++ +
Sbjct: 735  DPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTL 794

Query: 1050 QRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWR 1109
            QR+ R +L ++         +      AA +LQ  +R    RQ Y  +R AA+VIQ   R
Sbjct: 795  QRYCRGHLARRLA-------EHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTR 847

Query: 1110 DYYRRR-------HMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALK 1162
              + RR          A  IQ   + +   + +Q  R   I++Q   R  +AR+  KAL+
Sbjct: 848  AMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALR 907

Query: 1163 -EQRLRE--TKPEVGLVN--IKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNR 1217
             E R  E   +  VG+ N  ++    ++ Q  +             K + E  SV  S  
Sbjct: 908  IEARSAEHLKRLNVGMENKVVQLQRKIDEQNKE------------FKTLSEQLSVTTS-- 953

Query: 1218 ISRESSVDCLKESPNKQQERAQSQSGVDLQEDV--LVRERPRS------LEDLHQKKVGR 1269
             +    V+ LK+     Q+     + + LQE+V  L  E  R+      LED H ++   
Sbjct: 954  -TYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDE 1012

Query: 1270 AKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQG 1329
             +   +R+ +LEQ    L+  K +    I       ++   V E L       +    Q 
Sbjct: 1013 LR---KRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQN 1069

Query: 1330 SLELLSYEESQKSKLESVI-------------SDEGDLQFPS--PKISSSPKFDSRDNAL 1374
             ++  S  E +   L   +             S++  L+  S  P IS+S   D+ D AL
Sbjct: 1070 LVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTED-AL 1128

Query: 1375 SASNETSSAEHLKDGTM-----KEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQD-P 1428
                E    +   D T+     K +     E    + QL+     +S       PQ D  
Sbjct: 1129 QQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDID 1188

Query: 1429 LKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLK 1488
            L  N+ L  +  + + LE+E+   + L  D+N   +              + +S + +L 
Sbjct: 1189 LDPNADLAYNSLKRQELESEN---KKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLN 1245

Query: 1489 KLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAPSS- 1547
            +L+  + E E R         KE +  +R Q    ++ R A +  E P I      P+S 
Sbjct: 1246 QLKLAHEELEVR---------KEEVLILRTQIVSADQRRLAGRNAE-PNINARSSWPNSE 1295

Query: 1548 --YQSKQRVERPSSLLSLN--TSNKGELNVLGSLSLKDAALAQ 1586
                 +  +E    +   N  T + G LN  G L L    L Q
Sbjct: 1296 KHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQ 1338



 Score = 40.8 bits (94), Expect = 0.017
 Identities = 69/354 (19%), Positives = 146/354 (41%), Gaps = 45/354 (12%)

Query: 2101 GSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGL 2160
            G  NK+ +L++ +D   +        + V  S +   +  L   L+ ++       ++ L
Sbjct: 922  GMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRL 981

Query: 2161 QERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRC 2220
            QE  E++R       +L R H    ER I        +++  +  A+   +     +L+ 
Sbjct: 982  QEEVESLR------TELQRAHS---ERKILEDAHSREKDELRKRVAD---LEQENALLK- 1028

Query: 2221 PDTTDPL------QSVQDISKTTTCVELI---VVEQMNKYKARLKDISSLEFAENKAKTR 2271
             D  + L      QS  + ++ +    L+   + E+ ++Y+  +K+ S LE   +  +  
Sbjct: 1029 -DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDE 1087

Query: 2272 LSLIRRSMGKGRIRRG--------NYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDI-- 2321
            +++I+++ G  R            NYP  S+  +          EE    +AAM+  +  
Sbjct: 1088 MTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFL 1147

Query: 2322 -TEQQQAAMQQEERVLTEQIENLQKEKEELTFEMLVLEPRASDDETLESEASIGTAD--- 2377
              +++   ++QE + L  Q+E    ++E+   + +  EP  +D + L+  A +       
Sbjct: 1148 KLQKRVRELEQERKKLQVQLE----KREQQDSKKVQAEPPQTDID-LDPNADLAYNSLKR 1202

Query: 2378 ---SSENLNMESEYAISEKSERSLALSSLKTAGKSEPSSKLRKQLKKQQDSLDV 2428
                SEN  ++++     K+    A  +  + G  +  S L  QLK   + L+V
Sbjct: 1203 QELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  388 bits (996), Expect = e-107
 Identities = 218/538 (40%), Positives = 311/538 (57%), Gaps = 27/538 (5%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEK-IYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQ 207
           +DL +L  L+E  +L NLR RF   K IYTY G IL+ +NP+K LPIY    +  Y    
Sbjct: 70  NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129

Query: 208 LGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASG 267
           +G ++PHI+AVA+ AY  M +  +NQ I++SGESG+GKT S  + + +   +S+ G  + 
Sbjct: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189

Query: 268 VEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVY 327
           VE  +L + P+ EA GNAKT  N+NSSRFGK+ ++++ E   ++GA +  YLLEKSR+V+
Sbjct: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249

Query: 328 QEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
           Q  NERNYH+FY L A A + E     L   EE++Y                        
Sbjct: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNT----------------- 292

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRDDSIDIC 447
             +EG + R +    Q    ++GF    +  +F +L+AILHLGN+          S+   
Sbjct: 293 -VIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE- 350

Query: 448 NPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALF 507
           +   L +  ELL ++   + + L  RK VT  E ++ P    +AV  R+++AK +Y+ LF
Sbjct: 351 DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLF 410

Query: 508 DWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQ 567
           D+IV RIN AL  S       +   IGVLDI+GFE ++ NSFEQFCIN+ANE+LQ  FN 
Sbjct: 411 DFIVERINQALQFS-----GKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNM 465

Query: 568 HIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDK 627
           H+FKLEQEEY  E I W  ID+ DN   I+LI  K  G+L LLDEE   P  T++  L K
Sbjct: 466 HVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQK 524

Query: 628 FKHQHED-NSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSK 684
             +   + N   E P +   +F+I+H+A KV+Y  + F EKN D +   +V +LR+SK
Sbjct: 525 LYNNFVNRNPLFEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASK 582



 Score =  134 bits (338), Expect = 9e-31
 Identities = 103/418 (24%), Positives = 204/418 (48%), Gaps = 23/418 (5%)

Query: 876  KSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQ 935
            K ++  + K    ++ ++F++SL  LMETL    P++V+CI+ N EKLP  F    +++Q
Sbjct: 610  KQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQ 669

Query: 936  LRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPR---NIIPSKFNIQDFFRKINLNPD 992
            LR  G+LET+RI    Y S++++ +F S + +L+ +   +    K   +    ++  + +
Sbjct: 670  LRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVVLHRLIQDSN 729

Query: 993  NYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRF 1052
             YQ GKT +F +  +  +L+ L   ++ +  +++Q+  R  L R+ FL  R+A++IIQ++
Sbjct: 730  QYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQY 789

Query: 1053 WRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYY 1112
            +R     ++   A   K+A+    AA ++Q   R +L R  Y  +R A I +Q   R + 
Sbjct: 790  FRGQQTVRKAITAVALKEAW----AAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFL 845

Query: 1113 RRRHM-------AAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQR 1165
             RR          A+ +Q   +A+   +R+Q  R+ ++ +Q T   +R ++  K L++Q 
Sbjct: 846  ARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLT---YRVQRLQKKLEDQ- 901

Query: 1166 LRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVD 1225
                K   GLV  K      ++  D    +    +   KA    ++  E  +  R++  +
Sbjct: 902  ---NKENHGLVE-KLTSLAALRAGDVEKIQKLEAELE-KAATHRRNYEEKGKRYRDAVEE 956

Query: 1226 CLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQA 1283
             L +      E    +  + L+      E    +++L ++     ++E R+   LE++
Sbjct: 957  KLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS 1014


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  385 bits (989), Expect = e-106
 Identities = 224/555 (40%), Positives = 319/555 (57%), Gaps = 31/555 (5%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEK-IYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQ 207
           +DL +L  L+E  +L NLR RF   K IYTY G +L+ INP++ LPIY    +  Y    
Sbjct: 72  NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131

Query: 208 LGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASG 267
           +G ++PHI+AVA+ AY  M + ++NQ I++SGESG+GKT S  + + +   +S     + 
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191

Query: 268 VEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVY 327
           VE+ +L + P++E+ GNAKT  N+NSSRFGK+I++ + +   ++GA +  YLLEKSR+V+
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251

Query: 328 QEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
           Q   ERNYH+FY L A A   E     L   + ++Y  Q                  P  
Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQ---------------GGSP-- 294

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD-DSIDI 446
             +EG D   +    + A  ++G     +  IF +L+ ILHLGN+ +   T RD DS  I
Sbjct: 295 -VIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF---TSRDADSCTI 350

Query: 447 -CNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
               E L I  +L+ V  E +   L  RK  T  E  I P    +A   R+++AK +Y+ 
Sbjct: 351 PPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAK 410

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF+WIV  +N A L+S   +H+     IGVLDI+GFE +E NSFEQFCIN+ANE+LQ  F
Sbjct: 411 LFNWIVDNVNQA-LHSAVKQHS----FIGVLDIYGFETFEINSFEQFCINYANEKLQQQF 465

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLL 625
           N H+FKLEQEEY  E I W  ID+ DN  CINLI  K  G+L LLDEE   P+ T+ T  
Sbjct: 466 NMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWA 524

Query: 626 DKFKHQHEDN-SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSK 684
            K  + H +  +  E P +   AFII+H+A KV+Y  + F EKN D +  + + +L+SSK
Sbjct: 525 QKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSK 584

Query: 685 NAFISGMIGIDPVAV 699
              +  +   D  A+
Sbjct: 585 FKMLPELFQDDEKAI 599



 Score =  150 bits (380), Expect = 1e-35
 Identities = 115/421 (27%), Positives = 203/421 (48%), Gaps = 37/421 (8%)

Query: 884  KKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLE 943
            K+   ++  QF+ SL  LMETL    P++V+CI+ N  K P  F +   ++QLR  G+LE
Sbjct: 629  KEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688

Query: 944  TVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPS--KFNIQDFFRKINLNPDNYQVGKTMV 1001
            T+RI  +G+ S++++Q+F S + VL+ +  + S  K   ++   K+ L+ D YQ GKT +
Sbjct: 689  TIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI 748

Query: 1002 FLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQ 1061
            F +  +  +L+ L   ++    I +Q+  R  L R+ +L +R+A++ +QR+ R Y     
Sbjct: 749  FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGY----- 803

Query: 1062 VRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRR------- 1114
               A           AA ++Q  WR ++ R+RY   RAA IV+Q   R +  R       
Sbjct: 804  --QARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKIL 861

Query: 1115 RHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRL---RETKP 1171
            R   A+ IQ R + +     Y+     II LQ   R   A++  K LK +     R  K 
Sbjct: 862  REHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKL 921

Query: 1172 EVGLVN--IKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKE 1229
             +G+ N  ++    ++ Q  D        +   ++ +   + +  S      S ++ L+ 
Sbjct: 922  HIGMENKIMQLQRKVDEQNKD--------YKCLVEKLTNLEGIYNSETEKLRSDLERLQL 973

Query: 1230 SPNKQQERAQSQSG--VDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSL 1287
            S    +E A+  +G  + LQE+  + +  + LE    +K    +   R  +E EQ + +L
Sbjct: 974  S----EEEAKVATGRVLSLQEE--IAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027

Query: 1288 E 1288
            +
Sbjct: 1028 K 1028


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  385 bits (989), Expect = e-106
 Identities = 224/555 (40%), Positives = 319/555 (57%), Gaps = 31/555 (5%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEK-IYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQ 207
           +DL +L  L+E  +L NLR RF   K IYTY G +L+ INP++ LPIY    +  Y    
Sbjct: 72  NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131

Query: 208 LGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASG 267
           +G ++PHI+AVA+ AY  M + ++NQ I++SGESG+GKT S  + + +   +S     + 
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191

Query: 268 VEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVY 327
           VE+ +L + P++E+ GNAKT  N+NSSRFGK+I++ + +   ++GA +  YLLEKSR+V+
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251

Query: 328 QEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
           Q   ERNYH+FY L A A   E     L   + ++Y  Q                  P  
Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQ---------------GGSP-- 294

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD-DSIDI 446
             +EG D   +    + A  ++G     +  IF +L+ ILHLGN+ +   T RD DS  I
Sbjct: 295 -VIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF---TSRDADSCTI 350

Query: 447 -CNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
               E L I  +L+ V  E +   L  RK  T  E  I P    +A   R+++AK +Y+ 
Sbjct: 351 PPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAK 410

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF+WIV  +N A L+S   +H+     IGVLDI+GFE +E NSFEQFCIN+ANE+LQ  F
Sbjct: 411 LFNWIVDNVNQA-LHSAVKQHS----FIGVLDIYGFETFEINSFEQFCINYANEKLQQQF 465

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLL 625
           N H+FKLEQEEY  E I W  ID+ DN  CINLI  K  G+L LLDEE   P+ T+ T  
Sbjct: 466 NMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWA 524

Query: 626 DKFKHQHEDN-SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSK 684
            K  + H +  +  E P +   AFII+H+A KV+Y  + F EKN D +  + + +L+SSK
Sbjct: 525 QKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSK 584

Query: 685 NAFISGMIGIDPVAV 699
              +  +   D  A+
Sbjct: 585 FKMLPELFQDDEKAI 599



 Score =  150 bits (380), Expect = 1e-35
 Identities = 115/421 (27%), Positives = 203/421 (48%), Gaps = 37/421 (8%)

Query: 884  KKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLE 943
            K+   ++  QF+ SL  LMETL    P++V+CI+ N  K P  F +   ++QLR  G+LE
Sbjct: 629  KEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688

Query: 944  TVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPS--KFNIQDFFRKINLNPDNYQVGKTMV 1001
            T+RI  +G+ S++++Q+F S + VL+ +  + S  K   ++   K+ L+ D YQ GKT +
Sbjct: 689  TIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI 748

Query: 1002 FLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQ 1061
            F +  +  +L+ L   ++    I +Q+  R  L R+ +L +R+A++ +QR+ R Y     
Sbjct: 749  FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGY----- 803

Query: 1062 VRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRR------- 1114
               A           AA ++Q  WR ++ R+RY   RAA IV+Q   R +  R       
Sbjct: 804  --QARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKIL 861

Query: 1115 RHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRL---RETKP 1171
            R   A+ IQ R + +     Y+     II LQ   R   A++  K LK +     R  K 
Sbjct: 862  REHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKL 921

Query: 1172 EVGLVN--IKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKE 1229
             +G+ N  ++    ++ Q  D        +   ++ +   + +  S      S ++ L+ 
Sbjct: 922  HIGMENKIMQLQRKVDEQNKD--------YKCLVEKLTNLEGIYNSETEKLRSDLERLQL 973

Query: 1230 SPNKQQERAQSQSG--VDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSL 1287
            S    +E A+  +G  + LQE+  + +  + LE    +K    +   R  +E EQ + +L
Sbjct: 974  S----EEEAKVATGRVLSLQEE--IAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027

Query: 1288 E 1288
            +
Sbjct: 1028 K 1028


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score =  372 bits (954), Expect = e-102
 Identities = 216/563 (38%), Positives = 318/563 (56%), Gaps = 55/563 (9%)

Query: 144 QQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMY 203
           +Q   DD+  LP + E  +  NLR RF  + I+TY+GS+LI +NPFK +P +  + + +Y
Sbjct: 15  KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74

Query: 204 DNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKG 263
                 +  PHIYA+ D  Y  ML   +NQC++ISGESG+GKT +  +++ +++ +S  G
Sbjct: 75  QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGG 134

Query: 264 F-ASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEK 322
                V+ IIL + P+LEAFGNAKT  NNNSSRFGK+ ++ +   G   G  +  +LLEK
Sbjct: 135 EKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEK 194

Query: 323 SRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYD 382
           SR+V Q  NERN+H++Y LL GAS+++R    L  P+ Y+YLNQ                
Sbjct: 195 SRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQ---------------- 238

Query: 383 SEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNI--CYKKKTYR 440
              D + V+G D R DF     AM+++G  P  ++ +  L++ ILHLGNI  C      R
Sbjct: 239 --SDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYAR 296

Query: 441 DDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVT----VGEKLILPYKLAEAVTVRN 496
            +S+D+     L   + LL +    L E L +RK  +      E + +   + +A   R+
Sbjct: 297 VESVDL-----LAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRD 351

Query: 497 SMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINF 556
           ++AK LY+ LFD++V  IN A+   ++        SIGVLDI+GFE ++ N FEQFCINF
Sbjct: 352 ALAKGLYARLFDFLVEAINRAMQKPQE------EYSIGVLDIYGFEIFQKNGFEQFCINF 405

Query: 557 ANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKK--PTGLLHLLDEES 614
            NE+LQ  F +   K EQEEY  EGI W  I Y +N    +LI  K  P G++ +LD+  
Sbjct: 406 VNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVC 465

Query: 615 NFPQAT----NQTLLDKFK-----HQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFR 665
               AT    +QTLL K +     H+H ++            F+I HYAGKV Y V  F 
Sbjct: 466 ATMHATGGGADQTLLQKLQAAVGTHEHFNS--------WSAGFVIHHYAGKVSYDVSGFC 517

Query: 666 EKNTDHMRPDIVALLRSSKNAFI 688
           E+N D +  D++ L+++S+ AF+
Sbjct: 518 ERNRDVLFSDLIELMQTSEQAFL 540



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 49/194 (25%), Positives = 98/194 (50%), Gaps = 13/194 (6%)

Query: 883  KKKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGML 942
            KK +P +  ++ +   + L+ TL +  P++++CI+ N  K P  + +  V  Q+ Y G+ 
Sbjct: 552  KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLK 611

Query: 943  ETVRIRQSGYSSKYSFQDFVSHFHVLL----PRNIIPSKFNIQDFFRKINLNPDNYQVGK 998
            E +R+R++G++ +  F  F+  + +L     PR     +  +Q   R +N+ PD YQ+G 
Sbjct: 612  ENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGS 671

Query: 999  TMVFLKEQERQHLQDLLHQEVLRRI--ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNY 1056
            T VF+K  E   L + + +         + + W R +  R++     +AS I+       
Sbjct: 672  TKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNIL------- 724

Query: 1057 LNQKQVRDAAVQKD 1070
            LN+K+ R  ++ ++
Sbjct: 725  LNKKERRRNSINRN 738


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  370 bits (951), Expect = e-102
 Identities = 211/558 (37%), Positives = 327/558 (58%), Gaps = 39/558 (6%)

Query: 150 DLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLG 209
           D+  L  LNE+T + NL+ RF H +IYTY+GS++I +NP++ LPIY+P+ V+ Y N    
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 210 KLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGF-ASGV 268
           +L PHI+A++D AY ++  + K+QCI+I+GESG+GKT+++  ++ ++ A+  KG   + V
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           ++ +L + PVLEAFGNAKT  N+NSSRFGK++ + +   G  LG  +  YLLEKSR+V Q
Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQP-EEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
              ERN+HVFY LL+GASE+  +   L++    Y+YL+                    D 
Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-------------------DS 239

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD--DSID 445
             V G D   +F  ++ AM++VGF+      + ++++A+L LGNI +K ++  +  D   
Sbjct: 240 AKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESK 299

Query: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
           I +   L  + EL  + + +L  A   R      EK+     +A+A   R+++AK+LYS 
Sbjct: 300 IKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSR 359

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF W+V RIN ++      +   +   +GVLDI+GFE +E+NSFEQF IN+ NE+LQ  F
Sbjct: 360 LFSWLVNRINESI----KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIF 415

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFP-QATNQTL 624
            +   K EQEEY  E I W +IDY +N    +LI     G+L +LDEE   P   T++T 
Sbjct: 416 IELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETF 475

Query: 625 LDKFK-----HQHED------NSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMR 673
           L+K       HQH +      + ++   ++    F I+HYAGKV Y V+ F +KN D + 
Sbjct: 476 LEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLY 535

Query: 674 PDIVALLRSSKNAFISGM 691
            D+   +  + +A I  +
Sbjct: 536 RDLSQAMWKASHALIKSL 553



 Score =  123 bits (308), Expect = 3e-27
 Identities = 79/295 (26%), Positives = 154/295 (52%), Gaps = 32/295 (10%)

Query: 885  KKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLET 944
            K+PP+  +QF+AS++ LM+ L    P +++CI+ N +K    F++ LV  Q+RY G+LE 
Sbjct: 565  KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624

Query: 945  VRIRQSGYSSKYSFQDFVSHFHVLL----PRNIIPSKFNIQDFFRKINLNPDNYQVGKTM 1000
            VR+R++GY+ + +++  +  + +L     P    P++  ++  F ++ +  + Y  G++ 
Sbjct: 625  VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684

Query: 1001 VFLKEQERQ-HLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQ 1059
            +F++       L+DL  Q +     L+Q+ +R   CR HFL ++++ ++I  ++R Y  Q
Sbjct: 685  IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744

Query: 1060 KQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAA 1119
            K+ +            S+A ++Q+  R    R+   EL+            + +R   A 
Sbjct: 745  KRYQQT---------KSSALVIQSYIRGWKARKILRELK------------HQKRCKEAV 783

Query: 1120 ICIQARW---KAYRESKRYQEQRKK---IILLQSTCRGFRARQRFKALKEQRLRE 1168
              I A W   +A RE +R +E+ +    I ++ +   G +AR+  K LKE+  R+
Sbjct: 784  TTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRK 838


>gi|44889481 myosin IB isoform 2 [Homo sapiens]
          Length = 1078

 Score =  370 bits (951), Expect = e-102
 Identities = 211/558 (37%), Positives = 327/558 (58%), Gaps = 39/558 (6%)

Query: 150 DLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLG 209
           D+  L  LNE+T + NL+ RF H +IYTY+GS++I +NP++ LPIY+P+ V+ Y N    
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 210 KLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGF-ASGV 268
           +L PHI+A++D AY ++  + K+QCI+I+GESG+GKT+++  ++ ++ A+  KG   + V
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           ++ +L + PVLEAFGNAKT  N+NSSRFGK++ + +   G  LG  +  YLLEKSR+V Q
Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQP-EEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
              ERN+HVFY LL+GASE+  +   L++    Y+YL+                    D 
Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-------------------DS 239

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD--DSID 445
             V G D   +F  ++ AM++VGF+      + ++++A+L LGNI +K ++  +  D   
Sbjct: 240 AKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESK 299

Query: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
           I +   L  + EL  + + +L  A   R      EK+     +A+A   R+++AK+LYS 
Sbjct: 300 IKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSR 359

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF W+V RIN ++      +   +   +GVLDI+GFE +E+NSFEQF IN+ NE+LQ  F
Sbjct: 360 LFSWLVNRINESI----KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIF 415

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFP-QATNQTL 624
            +   K EQEEY  E I W +IDY +N    +LI     G+L +LDEE   P   T++T 
Sbjct: 416 IELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETF 475

Query: 625 LDKFK-----HQHED------NSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMR 673
           L+K       HQH +      + ++   ++    F I+HYAGKV Y V+ F +KN D + 
Sbjct: 476 LEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLY 535

Query: 674 PDIVALLRSSKNAFISGM 691
            D+   +  + +A I  +
Sbjct: 536 RDLSQAMWKASHALIKSL 553



 Score =  111 bits (278), Expect = 8e-24
 Identities = 66/258 (25%), Positives = 133/258 (51%), Gaps = 26/258 (10%)

Query: 885  KKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLET 944
            K+PP+  +QF+AS++ LM+ L    P +++CI+ N +K    F++ LV  Q+RY G+LE 
Sbjct: 565  KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624

Query: 945  VRIRQSGYSSKYSFQDFVSHFHVLL----PRNIIPSKFNIQDFFRKINLNPDNYQVGKTM 1000
            VR+R++GY+ + +++  +  + +L     P    P++  ++  F ++ +  + Y  G++ 
Sbjct: 625  VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684

Query: 1001 VFLKEQERQ-HLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQ 1059
            +F++       L+DL  Q +     L+Q+ +R   CR HFL ++++ ++I  ++R Y  Q
Sbjct: 685  IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744

Query: 1060 KQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAA 1119
            K+ +            S+A ++Q+  R    R+   EL+            + +R   A 
Sbjct: 745  KRYQQT---------KSSALVIQSYIRGWKARKILRELK------------HQKRCKEAV 783

Query: 1120 ICIQARWKAYRESKRYQE 1137
              I A W   +  + Y++
Sbjct: 784  TTIAAYWHGTQVRREYRK 801



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 5/82 (6%)

Query: 1089 LERQRYLELRAAAIVIQQKWRDYYRRRHM-----AAICIQARWKAYRESKRYQEQRKKII 1143
            LE  R   L   A +IQ+ +R +  R H      + I I A ++ Y + KRYQ+ +   +
Sbjct: 696  LEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSAL 755

Query: 1144 LLQSTCRGFRARQRFKALKEQR 1165
            ++QS  RG++AR+  + LK Q+
Sbjct: 756  VIQSYIRGWKARKILRELKHQK 777


>gi|240120050 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  370 bits (951), Expect = e-102
 Identities = 211/558 (37%), Positives = 327/558 (58%), Gaps = 39/558 (6%)

Query: 150 DLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLG 209
           D+  L  LNE+T + NL+ RF H +IYTY+GS++I +NP++ LPIY+P+ V+ Y N    
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 210 KLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGF-ASGV 268
           +L PHI+A++D AY ++  + K+QCI+I+GESG+GKT+++  ++ ++ A+  KG   + V
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138

Query: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328
           ++ +L + PVLEAFGNAKT  N+NSSRFGK++ + +   G  LG  +  YLLEKSR+V Q
Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198

Query: 329 EHNERNYHVFYYLLAGASEDERSAFHLKQP-EEYHYLNQITKKPLRQSWDDYCYDSEPDC 387
              ERN+HVFY LL+GASE+  +   L++    Y+YL+                    D 
Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-------------------DS 239

Query: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD--DSID 445
             V G D   +F  ++ AM++VGF+      + ++++A+L LGNI +K ++  +  D   
Sbjct: 240 AKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESK 299

Query: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
           I +   L  + EL  + + +L  A   R      EK+     +A+A   R+++AK+LYS 
Sbjct: 300 IKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSR 359

Query: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565
           LF W+V RIN ++      +   +   +GVLDI+GFE +E+NSFEQF IN+ NE+LQ  F
Sbjct: 360 LFSWLVNRINESI----KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIF 415

Query: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFP-QATNQTL 624
            +   K EQEEY  E I W +IDY +N    +LI     G+L +LDEE   P   T++T 
Sbjct: 416 IELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETF 475

Query: 625 LDKFK-----HQHED------NSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMR 673
           L+K       HQH +      + ++   ++    F I+HYAGKV Y V+ F +KN D + 
Sbjct: 476 LEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLY 535

Query: 674 PDIVALLRSSKNAFISGM 691
            D+   +  + +A I  +
Sbjct: 536 RDLSQAMWKASHALIKSL 553



 Score =  123 bits (308), Expect = 3e-27
 Identities = 79/295 (26%), Positives = 154/295 (52%), Gaps = 32/295 (10%)

Query: 885  KKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLET 944
            K+PP+  +QF+AS++ LM+ L    P +++CI+ N +K    F++ LV  Q+RY G+LE 
Sbjct: 565  KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624

Query: 945  VRIRQSGYSSKYSFQDFVSHFHVLL----PRNIIPSKFNIQDFFRKINLNPDNYQVGKTM 1000
            VR+R++GY+ + +++  +  + +L     P    P++  ++  F ++ +  + Y  G++ 
Sbjct: 625  VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684

Query: 1001 VFLKEQERQ-HLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQ 1059
            +F++       L+DL  Q +     L+Q+ +R   CR HFL ++++ ++I  ++R Y  Q
Sbjct: 685  IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744

Query: 1060 KQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAA 1119
            K+ +            S+A ++Q+  R    R+   EL+            + +R   A 
Sbjct: 745  KRYQQT---------KSSALVIQSYIRGWKARKILRELK------------HQKRCKEAV 783

Query: 1120 ICIQARW---KAYRESKRYQEQRKK---IILLQSTCRGFRARQRFKALKEQRLRE 1168
              I A W   +A RE +R +E+ +    I ++ +   G +AR+  K LKE+  R+
Sbjct: 784  TTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRK 838


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score =  366 bits (939), Expect = e-100
 Identities = 221/576 (38%), Positives = 332/576 (57%), Gaps = 45/576 (7%)

Query: 143 PQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKM 202
           P+    +D+  L  LNE ++L NLR R+    IYTY G   +V+NP+K LPIY+ K V M
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 203 YDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLT--ALS 260
           Y   +  ++ PHIYA+AD AY +MLQ +++Q I+ +GESG+GKT++T  +I +L   A S
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 261 QKG-----FASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYV 315
            KG         +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++N+  TG ++GA +
Sbjct: 202 HKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261

Query: 316 EKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQS 375
           E YLLEKSR + Q  +ER +H+FYY++AGA E  RS   L+    Y +L+     P+  +
Sbjct: 262 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSN-GFVPIPAA 320

Query: 376 WDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYK 435
            DD  +       TVE             AM ++GF  + +  I  ++S++L LGNI +K
Sbjct: 321 QDDEMFQE-----TVE-------------AMAIMGFSEEEQLSILKVVSSVLQLGNIVFK 362

Query: 436 KKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAE-AVTV 494
           K+    D   + +      V  L+ +       +++T + + VG  ++   +  E A   
Sbjct: 363 KER-NTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPR-IKVGRDVVQKAQTKEQADFA 420

Query: 495 RNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCI 554
             ++AK+ Y  LF WI+ R+N AL    D  H      +G+LDI GFE +E NSFEQ CI
Sbjct: 421 VEALAKATYERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCI 476

Query: 555 NFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDY-IDNTCCINLISK--KPTGLLHLLD 611
           N+ NE+LQ  FN  +F LEQEEY+ EGI W+ ID+ +D   CI LI +   P G+L LLD
Sbjct: 477 NYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLD 536

Query: 612 EESNFPQATNQTLLDKFKHQHEDNSYIEFPAVM--EPAFIIKHYAGKVKYGVKDFREKNT 669
           EE  FP+AT+++ ++K   +   +   + P  +  +  F I HYAGKV Y    +  KN 
Sbjct: 537 EECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNM 596

Query: 670 DHMRPDIVALLRSSKNAFISGM-------IGIDPVA 698
           D +  ++ +LL +S + F++ +       +G+D +A
Sbjct: 597 DPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMA 632



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 148/706 (20%), Positives = 293/706 (41%), Gaps = 105/706 (14%)

Query: 863  KHLTRLTLQDRITK----SLLHLHKKKKPP--SISAQFQASLSKLMETLGQAEPYFVKCI 916
            K + R+   D++ K    SL    K KK    ++   ++  L KLM TL    P FV+CI
Sbjct: 620  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679

Query: 917  RSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVL----LPRN 972
              N EK   +    LVL QLR  G+LE +RI + G+ ++  FQ+F   + +L    +P+ 
Sbjct: 680  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739

Query: 973  IIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRV 1032
             +  K       + + L+P+ Y++G++ +F +     HL++    ++   I+  Q   R 
Sbjct: 740  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799

Query: 1033 LLCRQHFLHLRQ---ASVIIQR------------FWRNYLNQKQVRDAAVQKDAFVMASA 1077
             L R+ F   +Q   A  +IQR            +WR +   K +     Q++   M + 
Sbjct: 800  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEE--MQAK 857

Query: 1078 AALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRY-- 1135
               LQ +     ERQ+  E       ++QK       +++    +QA  + Y E++    
Sbjct: 858  EDELQKT----KERQQKAENELKE--LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911

Query: 1136 ----QEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDP 1191
                ++Q  + IL +   R      R + L+ +R +  +    +++++     E      
Sbjct: 912  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ---MLDLEEQLEEEEAARQK 968

Query: 1192 SGWEDCSFDNRIKAIEECKSVI--ESNRISRESSVDCLKESPNKQQERAQSQSGVDLQED 1249
               E  + + +IK +E+   V+  ++N++S+E           K  E   S    +L E+
Sbjct: 969  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----------RKLLEERISDLTTNLAEE 1018

Query: 1250 VLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTE 1309
                E+ ++L  L  K          R+++ E++   LE LK +  G  S   ++    +
Sbjct: 1019 ---EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075

Query: 1310 LVPEGLQSPRGTPDSESSQGSLELLSYEESQKSK-LESVISDEGDLQFPSPKISSSPKFD 1368
                 L+      + E  Q +L  L  E +QK+  L+ +   EG +         S   +
Sbjct: 1076 AQIAELKMQLAKKE-EELQAALARLDDEIAQKNNALKKIRELEGHI---------SDLQE 1125

Query: 1369 SRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDP 1428
              D+  +A N+            K+      E    K +L+D+  S +         Q  
Sbjct: 1126 DLDSERAARNKAE----------KQKRDLGEELEALKTELEDTLDSTA--------TQQE 1167

Query: 1429 LKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLK 1488
            L+   + + ++ + K L+ E  + EA      +E R+ H    +++            L+
Sbjct: 1168 LRAKREQEVTVLK-KALDEETRSHEAQV----QEMRQKHAQAVEELTEQ---------LE 1213

Query: 1489 KLEKLNTEKEERQKQLQQQN-----EKEMMEQIRQQTDILEKERKA 1529
            + ++     ++ ++ L+++N     E  ++ Q +Q+ +  +K+ +A
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score =  366 bits (939), Expect = e-100
 Identities = 221/576 (38%), Positives = 332/576 (57%), Gaps = 45/576 (7%)

Query: 143 PQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKM 202
           P+    +D+  L  LNE ++L NLR R+    IYTY G   +V+NP+K LPIY+ K V M
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 203 YDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLT--ALS 260
           Y   +  ++ PHIYA+AD AY +MLQ +++Q I+ +GESG+GKT++T  +I +L   A S
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 261 QKG-----FASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYV 315
            KG         +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++N+  TG ++GA +
Sbjct: 202 HKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261

Query: 316 EKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQS 375
           E YLLEKSR + Q  +ER +H+FYY++AGA E  RS   L+    Y +L+     P+  +
Sbjct: 262 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSN-GFVPIPAA 320

Query: 376 WDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYK 435
            DD  +       TVE             AM ++GF  + +  I  ++S++L LGNI +K
Sbjct: 321 QDDEMFQE-----TVE-------------AMAIMGFSEEEQLSILKVVSSVLQLGNIVFK 362

Query: 436 KKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAE-AVTV 494
           K+    D   + +      V  L+ +       +++T + + VG  ++   +  E A   
Sbjct: 363 KER-NTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPR-IKVGRDVVQKAQTKEQADFA 420

Query: 495 RNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCI 554
             ++AK+ Y  LF WI+ R+N AL    D  H      +G+LDI GFE +E NSFEQ CI
Sbjct: 421 VEALAKATYERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCI 476

Query: 555 NFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDY-IDNTCCINLISK--KPTGLLHLLD 611
           N+ NE+LQ  FN  +F LEQEEY+ EGI W+ ID+ +D   CI LI +   P G+L LLD
Sbjct: 477 NYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLD 536

Query: 612 EESNFPQATNQTLLDKFKHQHEDNSYIEFPAVM--EPAFIIKHYAGKVKYGVKDFREKNT 669
           EE  FP+AT+++ ++K   +   +   + P  +  +  F I HYAGKV Y    +  KN 
Sbjct: 537 EECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNM 596

Query: 670 DHMRPDIVALLRSSKNAFISGM-------IGIDPVA 698
           D +  ++ +LL +S + F++ +       +G+D +A
Sbjct: 597 DPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMA 632



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 148/706 (20%), Positives = 293/706 (41%), Gaps = 105/706 (14%)

Query: 863  KHLTRLTLQDRITK----SLLHLHKKKKPP--SISAQFQASLSKLMETLGQAEPYFVKCI 916
            K + R+   D++ K    SL    K KK    ++   ++  L KLM TL    P FV+CI
Sbjct: 620  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679

Query: 917  RSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVL----LPRN 972
              N EK   +    LVL QLR  G+LE +RI + G+ ++  FQ+F   + +L    +P+ 
Sbjct: 680  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739

Query: 973  IIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRV 1032
             +  K       + + L+P+ Y++G++ +F +     HL++    ++   I+  Q   R 
Sbjct: 740  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799

Query: 1033 LLCRQHFLHLRQ---ASVIIQR------------FWRNYLNQKQVRDAAVQKDAFVMASA 1077
             L R+ F   +Q   A  +IQR            +WR +   K +     Q++   M + 
Sbjct: 800  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEE--MQAK 857

Query: 1078 AALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRY-- 1135
               LQ +     ERQ+  E       ++QK       +++    +QA  + Y E++    
Sbjct: 858  EDELQKT----KERQQKAENELKE--LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911

Query: 1136 ----QEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDP 1191
                ++Q  + IL +   R      R + L+ +R +  +    +++++     E      
Sbjct: 912  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ---MLDLEEQLEEEEAARQK 968

Query: 1192 SGWEDCSFDNRIKAIEECKSVI--ESNRISRESSVDCLKESPNKQQERAQSQSGVDLQED 1249
               E  + + +IK +E+   V+  ++N++S+E           K  E   S    +L E+
Sbjct: 969  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----------RKLLEERISDLTTNLAEE 1018

Query: 1250 VLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTE 1309
                E+ ++L  L  K          R+++ E++   LE LK +  G  S   ++    +
Sbjct: 1019 ---EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1075

Query: 1310 LVPEGLQSPRGTPDSESSQGSLELLSYEESQKSK-LESVISDEGDLQFPSPKISSSPKFD 1368
                 L+      + E  Q +L  L  E +QK+  L+ +   EG +         S   +
Sbjct: 1076 AQIAELKMQLAKKE-EELQAALARLDDEIAQKNNALKKIRELEGHI---------SDLQE 1125

Query: 1369 SRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDP 1428
              D+  +A N+            K+      E    K +L+D+  S +         Q  
Sbjct: 1126 DLDSERAARNKAE----------KQKRDLGEELEALKTELEDTLDSTA--------TQQE 1167

Query: 1429 LKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLK 1488
            L+   + + ++ + K L+ E  + EA      +E R+ H    +++            L+
Sbjct: 1168 LRAKREQEVTVLK-KALDEETRSHEAQV----QEMRQKHAQAVEELTEQ---------LE 1213

Query: 1489 KLEKLNTEKEERQKQLQQQN-----EKEMMEQIRQQTDILEKERKA 1529
            + ++     ++ ++ L+++N     E  ++ Q +Q+ +  +K+ +A
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score =  365 bits (937), Expect = e-100
 Identities = 224/583 (38%), Positives = 335/583 (57%), Gaps = 52/583 (8%)

Query: 143 PQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKM 202
           P+    +D+  L  LNE ++L NLR R+    IYTY G   +V+NP+K LPIY+ K V M
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 203 YDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLT--ALS 260
           Y   +  ++ PHIYA+AD AY +MLQ +++Q I+ +GESG+GKT++T  +I +L   A S
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 261 QKG-----------FASG-VEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETG 308
            KG           FA G +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++N+  TG
Sbjct: 202 HKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG 261

Query: 309 TVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQIT 368
            ++GA +E YLLEKSR + Q  +ER +H+FYY++AGA E  RS   L+    Y +L+   
Sbjct: 262 YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSN-G 320

Query: 369 KKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILH 428
             P+  + DD  +       TVE             AM ++GF  + +  I  ++S++L 
Sbjct: 321 FVPIPAAQDDEMFQE-----TVE-------------AMAIMGFSEEEQLSILKVVSSVLQ 362

Query: 429 LGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKL 488
           LGNI +KK+    D   + +      V  L+ +       +++T + + VG  ++   + 
Sbjct: 363 LGNIVFKKER-NTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPR-IKVGRDVVQKAQT 420

Query: 489 AE-AVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENN 547
            E A     ++AK+ Y  LF WI+ R+N AL    D  H      +G+LDI GFE +E N
Sbjct: 421 KEQADFAVEALAKATYERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVN 476

Query: 548 SFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDY-IDNTCCINLISK--KPT 604
           SFEQ CIN+ NE+LQ  FN  +F LEQEEY+ EGI W+ ID+ +D   CI LI +   P 
Sbjct: 477 SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPP 536

Query: 605 GLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVM--EPAFIIKHYAGKVKYGVK 662
           G+L LLDEE  FP+AT+++ ++K   +   +   + P  +  +  F I HYAGKV Y   
Sbjct: 537 GVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNAS 596

Query: 663 DFREKNTDHMRPDIVALLRSSKNAFISGM-------IGIDPVA 698
            +  KN D +  ++ +LL +S + F++ +       +G+D +A
Sbjct: 597 AWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMA 639



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 148/706 (20%), Positives = 293/706 (41%), Gaps = 105/706 (14%)

Query: 863  KHLTRLTLQDRITK----SLLHLHKKKKPP--SISAQFQASLSKLMETLGQAEPYFVKCI 916
            K + R+   D++ K    SL    K KK    ++   ++  L KLM TL    P FV+CI
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686

Query: 917  RSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVL----LPRN 972
              N EK   +    LVL QLR  G+LE +RI + G+ ++  FQ+F   + +L    +P+ 
Sbjct: 687  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746

Query: 973  IIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRV 1032
             +  K       + + L+P+ Y++G++ +F +     HL++    ++   I+  Q   R 
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 1033 LLCRQHFLHLRQ---ASVIIQR------------FWRNYLNQKQVRDAAVQKDAFVMASA 1077
             L R+ F   +Q   A  +IQR            +WR +   K +     Q++   M + 
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEE--MQAK 864

Query: 1078 AALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRY-- 1135
               LQ +     ERQ+  E       ++QK       +++    +QA  + Y E++    
Sbjct: 865  EDELQKT----KERQQKAENELKE--LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918

Query: 1136 ----QEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDP 1191
                ++Q  + IL +   R      R + L+ +R +  +    +++++     E      
Sbjct: 919  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ---MLDLEEQLEEEEAARQK 975

Query: 1192 SGWEDCSFDNRIKAIEECKSVI--ESNRISRESSVDCLKESPNKQQERAQSQSGVDLQED 1249
               E  + + +IK +E+   V+  ++N++S+E           K  E   S    +L E+
Sbjct: 976  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----------RKLLEERISDLTTNLAEE 1025

Query: 1250 VLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTE 1309
                E+ ++L  L  K          R+++ E++   LE LK +  G  S   ++    +
Sbjct: 1026 ---EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1082

Query: 1310 LVPEGLQSPRGTPDSESSQGSLELLSYEESQKSK-LESVISDEGDLQFPSPKISSSPKFD 1368
                 L+      + E  Q +L  L  E +QK+  L+ +   EG +         S   +
Sbjct: 1083 AQIAELKMQLAKKE-EELQAALARLDDEIAQKNNALKKIRELEGHI---------SDLQE 1132

Query: 1369 SRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDP 1428
              D+  +A N+            K+      E    K +L+D+  S +         Q  
Sbjct: 1133 DLDSERAARNKAE----------KQKRDLGEELEALKTELEDTLDSTA--------TQQE 1174

Query: 1429 LKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLK 1488
            L+   + + ++ + K L+ E  + EA      +E R+ H    +++            L+
Sbjct: 1175 LRAKREQEVTVLK-KALDEETRSHEAQV----QEMRQKHAQAVEELTEQ---------LE 1220

Query: 1489 KLEKLNTEKEERQKQLQQQN-----EKEMMEQIRQQTDILEKERKA 1529
            + ++     ++ ++ L+++N     E  ++ Q +Q+ +  +K+ +A
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score =  365 bits (937), Expect = e-100
 Identities = 224/583 (38%), Positives = 335/583 (57%), Gaps = 52/583 (8%)

Query: 143 PQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKM 202
           P+    +D+  L  LNE ++L NLR R+    IYTY G   +V+NP+K LPIY+ K V M
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 203 YDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLT--ALS 260
           Y   +  ++ PHIYA+AD AY +MLQ +++Q I+ +GESG+GKT++T  +I +L   A S
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 261 QKG-----------FASG-VEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETG 308
            KG           FA G +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++N+  TG
Sbjct: 202 HKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG 261

Query: 309 TVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQIT 368
            ++GA +E YLLEKSR + Q  +ER +H+FYY++AGA E  RS   L+    Y +L+   
Sbjct: 262 YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSN-G 320

Query: 369 KKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILH 428
             P+  + DD  +       TVE             AM ++GF  + +  I  ++S++L 
Sbjct: 321 FVPIPAAQDDEMFQE-----TVE-------------AMAIMGFSEEEQLSILKVVSSVLQ 362

Query: 429 LGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKL 488
           LGNI +KK+    D   + +      V  L+ +       +++T + + VG  ++   + 
Sbjct: 363 LGNIVFKKER-NTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPR-IKVGRDVVQKAQT 420

Query: 489 AE-AVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENN 547
            E A     ++AK+ Y  LF WI+ R+N AL    D  H      +G+LDI GFE +E N
Sbjct: 421 KEQADFAVEALAKATYERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVN 476

Query: 548 SFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDY-IDNTCCINLISK--KPT 604
           SFEQ CIN+ NE+LQ  FN  +F LEQEEY+ EGI W+ ID+ +D   CI LI +   P 
Sbjct: 477 SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPP 536

Query: 605 GLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVM--EPAFIIKHYAGKVKYGVK 662
           G+L LLDEE  FP+AT+++ ++K   +   +   + P  +  +  F I HYAGKV Y   
Sbjct: 537 GVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNAS 596

Query: 663 DFREKNTDHMRPDIVALLRSSKNAFISGM-------IGIDPVA 698
            +  KN D +  ++ +LL +S + F++ +       +G+D +A
Sbjct: 597 AWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMA 639



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 148/706 (20%), Positives = 293/706 (41%), Gaps = 105/706 (14%)

Query: 863  KHLTRLTLQDRITK----SLLHLHKKKKPP--SISAQFQASLSKLMETLGQAEPYFVKCI 916
            K + R+   D++ K    SL    K KK    ++   ++  L KLM TL    P FV+CI
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686

Query: 917  RSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVL----LPRN 972
              N EK   +    LVL QLR  G+LE +RI + G+ ++  FQ+F   + +L    +P+ 
Sbjct: 687  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746

Query: 973  IIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRV 1032
             +  K       + + L+P+ Y++G++ +F +     HL++    ++   I+  Q   R 
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 1033 LLCRQHFLHLRQ---ASVIIQR------------FWRNYLNQKQVRDAAVQKDAFVMASA 1077
             L R+ F   +Q   A  +IQR            +WR +   K +     Q++   M + 
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEE--MQAK 864

Query: 1078 AALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRY-- 1135
               LQ +     ERQ+  E       ++QK       +++    +QA  + Y E++    
Sbjct: 865  EDELQKT----KERQQKAENELKE--LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918

Query: 1136 ----QEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDP 1191
                ++Q  + IL +   R      R + L+ +R +  +    +++++     E      
Sbjct: 919  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ---MLDLEEQLEEEEAARQK 975

Query: 1192 SGWEDCSFDNRIKAIEECKSVI--ESNRISRESSVDCLKESPNKQQERAQSQSGVDLQED 1249
               E  + + +IK +E+   V+  ++N++S+E           K  E   S    +L E+
Sbjct: 976  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----------RKLLEERISDLTTNLAEE 1025

Query: 1250 VLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTE 1309
                E+ ++L  L  K          R+++ E++   LE LK +  G  S   ++    +
Sbjct: 1026 ---EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ 1082

Query: 1310 LVPEGLQSPRGTPDSESSQGSLELLSYEESQKSK-LESVISDEGDLQFPSPKISSSPKFD 1368
                 L+      + E  Q +L  L  E +QK+  L+ +   EG +         S   +
Sbjct: 1083 AQIAELKMQLAKKE-EELQAALARLDDEIAQKNNALKKIRELEGHI---------SDLQE 1132

Query: 1369 SRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDP 1428
              D+  +A N+            K+      E    K +L+D+  S +         Q  
Sbjct: 1133 DLDSERAARNKAE----------KQKRDLGEELEALKTELEDTLDSTA--------TQQE 1174

Query: 1429 LKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLK 1488
            L+   + + ++ + K L+ E  + EA      +E R+ H    +++            L+
Sbjct: 1175 LRAKREQEVTVLK-KALDEETRSHEAQV----QEMRQKHAQAVEELTEQ---------LE 1220

Query: 1489 KLEKLNTEKEERQKQLQQQN-----EKEMMEQIRQQTDILEKERKA 1529
            + ++     ++ ++ L+++N     E  ++ Q +Q+ +  +K+ +A
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266


>gi|4885503 myosin IA [Homo sapiens]
          Length = 1043

 Score =  363 bits (932), Expect = 1e-99
 Identities = 212/559 (37%), Positives = 325/559 (58%), Gaps = 39/559 (6%)

Query: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208
           +DL  L  L E++LL+NL+ R+++++IYTY+G+++I +NP++ LPIY P+++  Y ++  
Sbjct: 11  EDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYTF 70

Query: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKG-FASG 267
            +L+PHIYA+A+VAY ++  R ++QCI+I+GESGSGKT+++  ++ ++ A+  KG   + 
Sbjct: 71  YELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQVNS 130

Query: 268 VEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVY 327
           V++ +L + PVLEAFGNAKT  NNNSSRFGK++ + +   G+ LG  +  YLLEKSRLV 
Sbjct: 131 VKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRLVK 190

Query: 328 QEHNERNYHVFYYLLAGASEDERSAFHLKQPEE-YHYLNQITKKPLRQSWDDYCYDSEPD 386
           Q   ERN+H+FY LLAGA E    A  L++    Y YLN    +                
Sbjct: 191 QLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSR---------------- 234

Query: 387 CFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRD--DSI 444
              V+G D    F  +Q AM ++GF  +  RQ+  + S +L LGN+    +       + 
Sbjct: 235 ---VDGMDDASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPAS 291

Query: 445 DICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYS 504
            I +   +  + E++ +  E +  AL +R   T  EK++    + +A   R+++AK++YS
Sbjct: 292 GIRDGRGVREIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYS 351

Query: 505 ALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHY 564
            LFDWIV RIN ++     +    K   +GVLDI+GFE  E+NSFEQF IN+ NE+LQ  
Sbjct: 352 RLFDWIVNRINESI----KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQV 407

Query: 565 FNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFP-QATNQT 623
           F +   K EQEEY+ EGI W  +DY DN     LI     G+L +LDEE   P   ++ T
Sbjct: 408 FIEMTLKEEQEEYKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDST 467

Query: 624 LLDKF-----KHQHED-----NSYIEFPAVME-PAFIIKHYAGKVKYGVKDFREKNTDHM 672
            L K      KH H +     N+  ++   M    F I HYAGKV Y V  F +KN D +
Sbjct: 468 FLAKLNQLFSKHGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLL 527

Query: 673 RPDIVALLRSSKNAFISGM 691
             D++  +  +++  +  +
Sbjct: 528 FRDLLQAMWKAQHPLLRSL 546



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 63/233 (27%), Positives = 117/233 (50%), Gaps = 35/233 (15%)

Query: 885  KKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLET 944
            K+PP+  AQF++S++ LM+ L    P +++CI+ N  +   +FS  LV  Q RY G+LE 
Sbjct: 558  KRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLEN 617

Query: 945  VRIRQSGYSSKYSFQDFVSHFHVLLPRNIIP-----SKFNIQDFFRKINLNPDNYQVGKT 999
            VR+R++GY+ +  +  F+  +  LL R+  P      +  ++    +++++      GKT
Sbjct: 618  VRVRRAGYAHRQGYGPFLERYR-LLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKT 676

Query: 1000 MVF---------LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQ 1050
             +F         L+EQ R  LQ L          L+Q+ +R   CR H+  +R++ ++I 
Sbjct: 677  KIFIRSPKTLFYLEEQRRLRLQQL--------ATLIQKIYRGWRCRTHYQLMRKSQILIS 728

Query: 1051 RFWRNYLNQK---QVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAA 1100
             ++R  + +K   +++ + +   AFV           W+A    ++Y    AA
Sbjct: 729  SWFRGNMQKKCYGKIKASVLLIQAFV---------RGWKARKNYRKYFRSEAA 772



 Score = 39.7 bits (91), Expect = 0.038
 Identities = 22/77 (28%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 1088 HLERQRYLELRAAAIVIQQKWRDYYRRRHM-----AAICIQARWKAYRESKRYQEQRKKI 1142
            +LE QR L L+  A +IQ+ +R +  R H      + I I + ++   + K Y + +  +
Sbjct: 688  YLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASV 747

Query: 1143 ILLQSTCRGFRARQRFK 1159
            +L+Q+  RG++AR+ ++
Sbjct: 748  LLIQAFVRGWKARKNYR 764


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  360 bits (923), Expect = 1e-98
 Identities = 220/596 (36%), Positives = 333/596 (55%), Gaps = 43/596 (7%)

Query: 143 PQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKM 202
           P+    +D+  L  LNE ++L NL+ R+    IYTY G   +VINP+K LPIY+ + V+M
Sbjct: 78  PKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEM 137

Query: 203 YDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQ- 261
           Y   +  ++ PHIYA+ D AY +M+Q +++Q I+ +GESG+GKT++T  +I +L  ++  
Sbjct: 138 YKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASS 197

Query: 262 ---KGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKY 318
              K     +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++N+   G ++GA +E Y
Sbjct: 198 HKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETY 257

Query: 319 LLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDD 378
           LLEKSR + Q   ER +H+FYYLL+GA E  ++   L+   +Y +L+             
Sbjct: 258 LLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSN------------ 305

Query: 379 YCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKT 438
                     T+ G+  +  F+    AM ++G   + +  +  ++S +L LGNI +KK+ 
Sbjct: 306 -------GHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKER 358

Query: 439 YRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAE-AVTVRNS 497
              D   + +      VS LL +        ++T + + VG   +   +  E A     +
Sbjct: 359 -NTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPR-IKVGRDYVQKAQTKEQADFAIEA 416

Query: 498 MAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFA 557
           +AK+ Y  +F W+V RIN AL    D         IG+LDI GFE ++ NSFEQ CIN+ 
Sbjct: 417 LAKATYERMFRWLVLRINKAL----DKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYT 472

Query: 558 NERLQHYFNQHIFKLEQEEYRTEGISWHNIDY-IDNTCCINLISKK--PTGLLHLLDEES 614
           NE+LQ  FN  +F LEQEEY+ EGI W+ ID+ +D   CI+LI K   P G+L LLDEE 
Sbjct: 473 NEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEEC 532

Query: 615 NFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPA--FIIKHYAGKVKYGVKDFREKNTDHM 672
            FP+AT+++ ++K   +   +   + P  ++    F I HYAGKV Y   ++  KN D +
Sbjct: 533 WFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPL 592

Query: 673 RPDIVALLRSSKNAFISGM-------IGIDPVA-VFRWAILRAFFRAMVAFREAGK 720
             +I  LL  S + F+S +       IG+D VA +   A+  AF      FR  G+
Sbjct: 593 NDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQ 648



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 171/792 (21%), Positives = 314/792 (39%), Gaps = 106/792 (13%)

Query: 889  SISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIR 948
            ++   ++  L+KLM TL    P FV+CI  N EK   +    LVL QLR  G+LE +RI 
Sbjct: 645  TVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRIC 704

Query: 949  QSGYSSKYSFQDFVSHFHVL----LPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLK 1004
            + G+ ++  FQ+F   + +L    +P+  +  K       + + L+ + Y++G++ VF +
Sbjct: 705  RQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFR 764

Query: 1005 EQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQ---ASVIIQR---------- 1051
                 HL++    ++   II  Q   R  L R+ F   +Q   A  ++QR          
Sbjct: 765  AGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRN 824

Query: 1052 --FWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRA-AAIVIQQKW 1108
              +WR +   K +   + Q++  +MA    L++   +      R  E+    + ++ +K 
Sbjct: 825  WQWWRLFTKVKPLLQVSRQEEE-MMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKL 883

Query: 1109 RDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRE 1168
            +   + +    +C +A     R + + QE       L+  C    AR   +  + Q L+ 
Sbjct: 884  QLQEQLQAETELCAEAEELRARLTAKKQE-------LEEICHDLEARVEEEEERCQHLQA 936

Query: 1169 TKPEV--GLVNIKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDC 1226
             K ++   +  ++     E         E  + + ++K +EE + ++E          +C
Sbjct: 937  EKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ--------NC 988

Query: 1227 LKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFS 1286
                  K  E   ++   +L E+    E+ +SL  L  K          R+R  E+    
Sbjct: 989  KLAKEKKLLEDRIAEFTTNLTEE---EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQE 1045

Query: 1287 LELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQKSKLES 1346
            LE  + R L G S               L        ++ ++  ++L   EE  ++ L  
Sbjct: 1046 LEKTR-RKLEGDSTD-------------LSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091

Query: 1347 VISDEGDLQFPSPKISSSPKFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKP 1406
            V  +         KI    + +S+ + L    E+  A   K    K  +    E    K 
Sbjct: 1092 VEEEAAQKNMALKKIR---ELESQISELQEDLESERASRNKAEKQKRDL--GEELEALKT 1146

Query: 1407 QLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRY 1466
            +L+D+  S +         Q  L++  + + +I + K LE E    EA      +E R+ 
Sbjct: 1147 ELEDTLDSTA--------AQQELRSKREQEVNILK-KTLEEEAKTHEAQI----QEMRQK 1193

Query: 1467 HCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKE 1526
            H    +++   L  E +  V   LEK     E  + +L   NE +++  ++ + D   K 
Sbjct: 1194 HSQAVEELAEQL--EQTKRVKANLEKAKQTLENERGEL--ANEVKVL--LQGKGDSEHKR 1247

Query: 1527 RKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSLLSLNTSNKGEL-NVLGSLSLKDAALA 1585
            +K    +++ ++         +   +RV   + L    T  + EL NV G LS       
Sbjct: 1248 KKVEAQLQELQV--------KFNEGERVR--TELADKVTKLQVELDNVTGLLS------- 1290

Query: 1586 QKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQLNVACK-LSNNRISKR 1644
            Q DS S+ L       T  F    S  Q  T + L + +R    L+   K + + + S R
Sbjct: 1291 QSDSKSSKL-------TKDFSALESQLQ-DTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342

Query: 1645 EHFRPTQSYSHN 1656
            E     +   HN
Sbjct: 1343 EQLEEEEEAKHN 1354



 Score = 32.7 bits (73), Expect = 4.7
 Identities = 49/239 (20%), Positives = 93/239 (38%), Gaps = 20/239 (8%)

Query: 2308 EETLTSEAAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEMLVLEPR-ASDDET 2366
            EE+   +  +E   TE +   +++E+ +L +Q   L KEK+ L   +         ++E 
Sbjct: 955  EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK 1014

Query: 2367 LESEASIGTADSSENLNMESEYAISEKSERSLALSSLKTAGKSEPSS-----------KL 2415
             +S A +     +   ++E      EK  + L  +  K  G S   S           +L
Sbjct: 1015 SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074

Query: 2416 RKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYS---KSPFYRAASGNEALGME 2472
            + QL K+++ L    + V         +    R+L    S   +      AS N+A   +
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQK 1134

Query: 2473 GPLGQ-----TKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTVMSGRRK 2526
              LG+        LED     +       K +Q++  +K + ++  +T E  +   R+K
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193


>gi|51100974 myosin ID [Homo sapiens]
          Length = 1006

 Score =  360 bits (923), Expect = 1e-98
 Identities = 209/560 (37%), Positives = 327/560 (58%), Gaps = 49/560 (8%)

Query: 150 DLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLG 209
           D  S+P+      + NLR RF+  +IYT++G +++ +NP+K L IY    ++ Y   +L 
Sbjct: 18  DTVSMPEF-----MANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72

Query: 210 KLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTAL---SQKGFAS 266
           +  PH++A+AD AY AM +R K+ CIVISGESG+GKT+++ +++ ++ A+   SQ+    
Sbjct: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132

Query: 267 GVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLV 326
            V+ ++L +  VLEAFGNAKT  N+NSSRFGK++ +N+   G  +G ++  YLLEKSR++
Sbjct: 133 RVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVI 192

Query: 327 YQEHNERNYHVFYYLLAGASEDERSAFHL-KQPEEYHYLNQITKKPLRQSWDDYCYDSEP 385
            Q+  ER++H FY LL G SE    + HL K    Y+Y++      L+ S +D       
Sbjct: 193 VQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIH--VGAQLKSSINDAA----- 245

Query: 386 DCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRDDSID 445
                       +F  +  AM+++GF P+  + ++ +L+AILHLGN+   K     D+  
Sbjct: 246 ------------EFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNL---KFVVDGDTPL 290

Query: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505
           I N +V+ I++ELL  K +M+ +AL+ R   T  + +   +   EA   R++ AK++Y  
Sbjct: 291 IENGKVVSIIAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYER 350

Query: 506 LFDWIVFRINHAL-LNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHY 564
           LF WIV RIN  + + + D   + K   IGVLDI+GFE ++NNSFEQFCIN+ NE+LQ  
Sbjct: 351 LFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQL 410

Query: 565 FNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEE-SNFPQATNQT 623
           F Q + K EQEEY+ EGI W +IDY +N   ++L+ ++  G++ +LD+   N  + T++ 
Sbjct: 411 FIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEM 470

Query: 624 LLDKF-----KHQH-------EDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDH 671
            L+       KH H         +  +EF    +  F I+HYAG V Y V  F +KN D 
Sbjct: 471 FLEALNSKLGKHAHFSSRKLCASDKILEF----DRDFRIRHYAGDVVYSVIGFIDKNKDT 526

Query: 672 MRPDIVALLRSSKNAFISGM 691
           +  D   L+ +S N  +  M
Sbjct: 527 LFQDFKRLMYNSSNPVLKNM 546



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 52/188 (27%), Positives = 102/188 (54%), Gaps = 8/188 (4%)

Query: 885  KKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLET 944
            K+P + +  F+ S+  L++ L   EPY+V+CI+ N +K P  F D     Q+ Y G+LE 
Sbjct: 559  KRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLEN 618

Query: 945  VRIRQSGYSSKYSFQDFVSHFHVL----LPRNIIPS-KFNIQDFFRKINLNPDNYQVGKT 999
            VR+R++G++ + +++ F+  + ++     P + +PS K  ++    +     D+   GKT
Sbjct: 619  VRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQ-DDVAYGKT 677

Query: 1000 MVFLKEQERQH-LQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLN 1058
             +F++       L++L  Q ++R ++ LQ+ +R  L R  +   + A  II R++R Y  
Sbjct: 678  KIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTII-RYYRRYKV 736

Query: 1059 QKQVRDAA 1066
            +  + + A
Sbjct: 737  KSYIHEVA 744


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  355 bits (911), Expect = 3e-97
 Identities = 215/575 (37%), Positives = 325/575 (56%), Gaps = 45/575 (7%)

Query: 143 PQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKM 202
           P+    +D+  L  LNE ++L NL++R+    IYTY G   +VINP+K LPIY+   ++M
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEM 141

Query: 203 YDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLT--ALS 260
           Y   +  ++ PHIYA+++ AY  MLQ +++Q I+ +GESG+GKT++T  +I +L   A S
Sbjct: 142 YRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS 201

Query: 261 QKG-----FASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYV 315
            KG         +E+ +L A P+LE+FGNAKT  N+NSSRFGKFI++N+  TG ++GA +
Sbjct: 202 HKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261

Query: 316 EKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQS 375
           E YLLEKSR V Q  +ER +H+FY LL+GA E  +S   L+    Y +L+          
Sbjct: 262 ETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSN--------- 312

Query: 376 WDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYK 435
                         + G+  + +F+    AM ++GF  +    +  ++S++L  GNI +K
Sbjct: 313 ----------GYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFK 362

Query: 436 KKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAE-AVTV 494
           K+    D   +    V   +  LL +       A++T + + VG   +   +  E A   
Sbjct: 363 KER-NTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPR-IKVGRDYVQKAQTKEQADFA 420

Query: 495 RNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCI 554
             ++AK+ Y  LF W+V RIN AL    D         IG+LDI GFE +E NSFEQ CI
Sbjct: 421 VEALAKATYERLFRWLVHRINKAL----DRTKRQGASFIGILDIAGFEIFELNSFEQLCI 476

Query: 555 NFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDY-IDNTCCINLISK--KPTGLLHLLD 611
           N+ NE+LQ  FN  +F LEQEEY+ EGI W+ ID+ +D   CI+LI +   P G+L LLD
Sbjct: 477 NYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLD 536

Query: 612 EESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPA--FIIKHYAGKVKYGVKDFREKNT 669
           EE  FP+AT++T ++K   +   +S  + P  ++    F I HYAGKV Y   ++  KN 
Sbjct: 537 EECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNM 596

Query: 670 DHMRPDIVALLRSSKNAFISGM-------IGIDPV 697
           D +  ++  LL  S + F++ +       +G+D V
Sbjct: 597 DPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQV 631



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 135/706 (19%), Positives = 290/706 (41%), Gaps = 127/706 (17%)

Query: 883  KKKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGML 942
            KK    ++   ++ SL+KLM TL    P FV+CI  N EK   +    LVL QLR  G+L
Sbjct: 646  KKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVL 705

Query: 943  ETVRIRQSGYSSKYSFQDFVSHFHVL----LPRNIIPSKFNIQDFFRKINLNPDNYQVGK 998
            E +RI + G+ ++  FQ+F   + +L    +P+  +  K   +   R + L+P+ Y++G+
Sbjct: 706  EGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765

Query: 999  TMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQ---ASVIIQR---- 1051
            + +F +     HL++    ++   II  Q   R  L R+ F   +Q   A  ++QR    
Sbjct: 766  SKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAA 825

Query: 1052 --------FWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIV 1103
                    +WR +   K +     Q++  + A    LL+        +++  ++      
Sbjct: 826  YLKLRHWQWWRVFTKVKPLLQVTRQEEE-LQAKDEELLKV-------KEKQTKVEGELEE 877

Query: 1104 IQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKE 1163
            +++K +     +++ A  +QA  + + E+   +E R ++                 A K+
Sbjct: 878  MERKHQQLLEEKNILAEQLQAETELFAEA---EEMRARL-----------------AAKK 917

Query: 1164 QRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESS 1223
            Q L E   ++                          ++R++  EE   ++++ +   ++ 
Sbjct: 918  QELEEILHDL--------------------------ESRVEEEEERNQILQNEKKKMQAH 951

Query: 1224 VDCLKESPNKQQ--------ERAQSQSGVDLQEDVLVRERPRSLEDLHQKKV--GRAKRE 1273
            +  L+E  ++++        E+  +++ +   E+ ++    ++ + + +KK+   R    
Sbjct: 952  IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011

Query: 1274 SRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESS------ 1327
            S ++ E E+   +L  ++ +    IS  E+R    E   + L+  +   D E++      
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1071

Query: 1328 ---QGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNETSSAE 1384
               Q  ++ L  + ++K +        GD +      +     + +        +  S +
Sbjct: 1072 AELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEK 1131

Query: 1385 HLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKL 1444
              ++   K+    S E    K +L+D+  + +         Q  L+T  + + + +  K 
Sbjct: 1132 ASRNKAEKQKRDLSEELEALKTELEDTLDTTA--------AQQELRTKREQEVA-ELKKA 1182

Query: 1445 LENEDTAGEALTLDINRETRRYHCSGKDQIVPSL---------------NTESSNPVL-- 1487
            LE E    EA   D+    R+ H +  +++   L                 E+ N  L  
Sbjct: 1183 LEEETKNHEAQIQDM----RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELAC 1238

Query: 1488 --KKLEKLNTEKEERQKQLQQQNEK---EMMEQIRQQTDILEKERK 1528
              K L+++  E E ++K+L  Q ++   ++ E  R + ++ EK  K
Sbjct: 1239 EVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASK 1284


>gi|124494247 myosin IC isoform b [Homo sapiens]
          Length = 1044

 Score =  351 bits (900), Expect = 6e-96
 Identities = 199/546 (36%), Positives = 312/546 (57%), Gaps = 35/546 (6%)

Query: 158 NEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYA 217
           +E   +ENLR RF+   IYTY+G +L+ +NP++ L IY+ ++++ Y      ++ PH++A
Sbjct: 40  SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFA 99

Query: 218 VADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASG-VEQIILGAG 276
           VAD  Y A+   +++Q ++ISGESG+GKT++T  L+             G V   +L + 
Sbjct: 100 VADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSN 159

Query: 277 PVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYH 336
           PVLEAFGNAKT  N+NSSRFGK++ V +   G  +G ++  YLLEKSR+V+Q H ERN+H
Sbjct: 160 PVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFH 219

Query: 337 VFYYLLAGASEDERSAFHL-KQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDL 395
           +FY LL G  E+      L + P+ Y YL                   +  C  V   + 
Sbjct: 220 IFYQLLEGGEEETLRRLGLERNPQSYLYL------------------VKGQCAKVSSIND 261

Query: 396 RHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRDDSIDICNPEVLPIV 455
           + D++ ++ A+ ++ F       + S+++++LHLGNI +      + +  +     L  +
Sbjct: 262 KSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAAN--EESNAQVTTENQLKYL 319

Query: 456 SELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRIN 515
           + LL V+   L EAL  RK +  GE+L+ P  L +A   R+++AK++YS  F W+V +IN
Sbjct: 320 TRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKIN 379

Query: 516 HALLNSKDLEHNT--KTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQHIFKLE 573
            +L  SKD+E  +   T  +G+LDI+GFE +++NSFEQFCIN+ NE+LQ  F +   K E
Sbjct: 380 RSLA-SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSE 438

Query: 574 QEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFP-QATNQTLLDKF---- 628
           QEEY  EGI+W  + Y +N    +L+ +K  G++ +LDEE   P +AT+ T L+K     
Sbjct: 439 QEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTV 498

Query: 629 KHQ-----HEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSS 683
           KH      H+        ++    F + HYAG+V Y V  F +KN D +  ++   + SS
Sbjct: 499 KHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSS 558

Query: 684 KNAFIS 689
           KN  +S
Sbjct: 559 KNPIMS 564



 Score =  102 bits (254), Expect = 5e-21
 Identities = 55/186 (29%), Positives = 103/186 (55%), Gaps = 5/186 (2%)

Query: 881  LHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTG 940
            L  KK+P +++ QF+ SL +L+E L   EP +V+CI+ N  K P RF +VL+  Q++Y G
Sbjct: 572  LSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLG 631

Query: 941  MLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQD----FFRKINLNPDNYQV 996
            +LE +R+R++G++ +  ++ F+  +  L P          QD      R +   P+ Y++
Sbjct: 632  LLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKM 691

Query: 997  GKTMVFLKEQERQH-LQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRN 1055
            G+T +F++  +     +D L          +Q  +R    RQ FL ++++++ IQ +WR 
Sbjct: 692  GRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRG 751

Query: 1056 YLNQKQ 1061
             L +++
Sbjct: 752  TLGRRK 757


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,566,488
Number of Sequences: 37866
Number of extensions: 4295463
Number of successful extensions: 23376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 379
Number of HSP's that attempted gapping in prelim test: 19320
Number of HSP's gapped (non-prelim): 3463
length of query: 2548
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2429
effective length of database: 13,741,464
effective search space: 33378016056
effective search space used: 33378016056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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