Guide to the Human Genome
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Search of human proteins with 155969714

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|155969714 nuclear protein,  ataxia-telangiectasia locus
[Homo sapiens]
         (1427 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo...  2791   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    79   3e-14
gi|91982772 mucin 17 [Homo sapiens]                                    70   1e-11
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        55   5e-07
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    52   3e-06
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    49   3e-05
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            47   1e-04
gi|8923040 CDKN2A interacting protein [Homo sapiens]                   47   1e-04
gi|83367077 mucin 16 [Homo sapiens]                                    47   2e-04
gi|167736355 mucin 4 isoform a [Homo sapiens]                          46   3e-04
gi|149944526 additional sex combs like 3 [Homo sapiens]                46   3e-04
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    45   4e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    45   4e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    45   7e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    45   7e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    45   7e-04
gi|113722133 senataxin [Homo sapiens]                                  44   9e-04
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    44   0.001
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         44   0.001
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              44   0.001
gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens]                    43   0.002
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti...    43   0.002
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 42   0.006
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    41   0.007
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 41   0.009
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 41   0.009
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  41   0.009
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    41   0.009
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    41   0.009
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    40   0.012

>gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo
            sapiens]
          Length = 1427

 Score = 2791 bits (7234), Expect = 0.0
 Identities = 1427/1427 (100%), Positives = 1427/1427 (100%)

Query: 1    MLLPSDVARLVLGYLQQENLISTCQTFILESSDLKEYAEHCTDEGFIPACLLSLFGKNLT 60
            MLLPSDVARLVLGYLQQENLISTCQTFILESSDLKEYAEHCTDEGFIPACLLSLFGKNLT
Sbjct: 1    MLLPSDVARLVLGYLQQENLISTCQTFILESSDLKEYAEHCTDEGFIPACLLSLFGKNLT 60

Query: 61   TILNEYVAMKTKETSNNVPAIMSSLWKKLDHTLSQIRSMQSSPRFAGSQRARTRTGIAEI 120
            TILNEYVAMKTKETSNNVPAIMSSLWKKLDHTLSQIRSMQSSPRFAGSQRARTRTGIAEI
Sbjct: 61   TILNEYVAMKTKETSNNVPAIMSSLWKKLDHTLSQIRSMQSSPRFAGSQRARTRTGIAEI 120

Query: 121  KRQRKLASQTAPASAELLTLPYLSGQFTTPPSTGTQVTRPSGQISDPSRSYFVVVNHSQS 180
            KRQRKLASQTAPASAELLTLPYLSGQFTTPPSTGTQVTRPSGQISDPSRSYFVVVNHSQS
Sbjct: 121  KRQRKLASQTAPASAELLTLPYLSGQFTTPPSTGTQVTRPSGQISDPSRSYFVVVNHSQS 180

Query: 181  QDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKSTTLSGPHSTIRNFQDPNAFAV 240
            QDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKSTTLSGPHSTIRNFQDPNAFAV
Sbjct: 181  QDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKSTTLSGPHSTIRNFQDPNAFAV 240

Query: 241  EKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLG 300
            EKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLG
Sbjct: 241  EKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLG 300

Query: 301  LPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVL 360
            LPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVL
Sbjct: 301  LPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVL 360

Query: 361  ADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQIS 420
            ADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQIS
Sbjct: 361  ADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQIS 420

Query: 421  TSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETE 480
            TSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETE
Sbjct: 421  TSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETE 480

Query: 481  MAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSL 540
            MAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSL
Sbjct: 481  MAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSL 540

Query: 541  TGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSC 600
            TGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSC
Sbjct: 541  TGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSC 600

Query: 601  LQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQ 660
            LQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQ
Sbjct: 601  LQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQ 660

Query: 661  EPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNT 720
            EPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNT
Sbjct: 661  EPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNT 720

Query: 721  DDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSP 780
            DDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSP
Sbjct: 721  DDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSP 780

Query: 781  TKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVT 840
            TKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVT
Sbjct: 781  TKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVT 840

Query: 841  PCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQ 900
            PCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQ
Sbjct: 841  PCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQ 900

Query: 901  PLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNN 960
            PLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNN
Sbjct: 901  PLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNN 960

Query: 961  FSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGC 1020
            FSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGC
Sbjct: 961  FSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGC 1020

Query: 1021 HAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPN 1080
            HAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPN
Sbjct: 1021 HAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPN 1080

Query: 1081 HKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT 1140
            HKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT
Sbjct: 1081 HKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT 1140

Query: 1141 IRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKS 1200
            IRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKS
Sbjct: 1141 IRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKS 1200

Query: 1201 IASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLA 1260
            IASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLA
Sbjct: 1201 IASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLA 1260

Query: 1261 DSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPAS 1320
            DSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPAS
Sbjct: 1261 DSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPAS 1320

Query: 1321 ETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERER 1380
            ETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERER
Sbjct: 1321 ETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERER 1380

Query: 1381 NSRPSSKNLTNSSIPMKKKKIKKKKLPSSFPAGMDVDKFLLSLHYDE 1427
            NSRPSSKNLTNSSIPMKKKKIKKKKLPSSFPAGMDVDKFLLSLHYDE
Sbjct: 1381 NSRPSSKNLTNSSIPMKKKKIKKKKLPSSFPAGMDVDKFLLSLHYDE 1427


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 112/501 (22%), Positives = 214/501 (42%), Gaps = 19/501 (3%)

Query: 333  DYGKTKNNKNISQSISSQPMESNPSIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQN 392
            D  K+ + K  S S  S   +S+ S   +D ++     S  + +SD      +  +   +
Sbjct: 536  DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595

Query: 393  DDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDIT--FESVPNL 450
             D  N+  +S++ D     D  + S  S S   K+   +  ++ K D   +   +S  N 
Sbjct: 596  SDSSNSSDSSDSSDSSDSSDSSDSSD-SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 451  NDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPIT 510
            +  +   +SN+  +   ++   +  S+++  +     +S SSN  SES    D  D    
Sbjct: 655  DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN-SSESSDSSDSSD---- 709

Query: 511  SFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSS 570
            S  S   +++N N   S  S+   S D+S     S  S    NS+D+     + + S SS
Sbjct: 710  SDSSDSSDSSNSNSSDSDSSNSSDSSDSS-NSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768

Query: 571  DSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLS 630
            DSS+   S    N      S  SN   NS   S+    S  S+  + S   +    DS S
Sbjct: 769  DSSDSSDSSDSSN------SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS-S 821

Query: 631  STKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPP 690
            ++   SN S S + +++ + + +S S +  +  SS + +++       +++    + +  
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD 881

Query: 691  EGTPVENSHSL-PPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPF 749
                 E+S+S    +S  SS  DS   S ++D   SSN+S   ++SN  S     S D  
Sbjct: 882  SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN--SSDNSNSSDSS 939

Query: 750  VSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSAS 809
             SSD+  +S  S+ +  +  +   +S   S + +++     +S ++  +   ++  DS+ 
Sbjct: 940  NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999

Query: 810  MEQSLLTFKSEDSAVNNTQNE 830
               S  +  S DS+ ++  ++
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSD 1020



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 108/493 (21%), Positives = 194/493 (39%), Gaps = 8/493 (1%)

Query: 377 SDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFK-TAVPTE 435
           SDG         S Q DDP ++ +++ N D   + D  + S+   S      K     ++
Sbjct: 447 SDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSD 506

Query: 436 QKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVP 495
            K   D   +S  + N+ +  GN N   + +         S  ++       NS  S+  
Sbjct: 507 SKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDS 566

Query: 496 SESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSN 555
           S+S            S  S   ++++ +   S  SS   S D+S +   S  S   ++ +
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDSKS 624

Query: 556 DTVKLKINFHGSKS-SDSSEVHKSKIEINVLEPVMSQLSNCQDNS-CLQSEILPVSVESS 613
           D+ K + +   S S SDSS+ + S    N      S  SN  D+S    S     S +SS
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684

Query: 614 HLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTEN-EAQASKSENSQEPSSSVKEENTI 672
           + + S         S SS    S+DS S + + + N  +  S S NS + S S    ++ 
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744

Query: 673 FLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEI 732
             S   N++    +      +   +S      S  S+  DS+  S ++D   SSN+S   
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 733 DASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSS 792
           ++S+          D   SSD+  +S  S  +  +  +    S   S + ++      +S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 793 EETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQL 852
            ++  +   +   DS+    S  +  S DS+ ++  ++   + S+N +   S D      
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD--SSDSSNSSD 922

Query: 853 MPATSTAFGNSNN 865
              +S +  NSN+
Sbjct: 923 SSESSNSSDNSNS 935



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 120/591 (20%), Positives = 223/591 (37%), Gaps = 39/591 (6%)

Query: 255  SNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQD 314
            SN +  +  + N +    S N+         +N ++   S D      S          D
Sbjct: 719  SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778

Query: 315  ILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVLADETNLAVKGSFET 374
                ++S+ +  +  D  D   + ++ N S S  S     + S   +D +N        +
Sbjct: 779  SSNSSDSNDSSNSS-DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN-------SS 830

Query: 375  EESDGQSGQPAFCTSYQND----DPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKT 430
            + SD  +   +  +S  +D    D  N   +SN+ D     D  N S  S S        
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890

Query: 431  AVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSL 490
            +  +    +   + +S  + N  +   +SN+  +   +    N  S+++        NS 
Sbjct: 891  SSDSSDSSNSSDS-DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS-------NSS 942

Query: 491  SSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQF 550
             S+  S+S    D  +   +S  S   ++N+     S  S    S D+S +   S  S  
Sbjct: 943  DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS-----SDSSDSSNSSDSSDSSDSSDSSDS 997

Query: 551  CENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPV-- 608
             ++SN +         S SSDSS+   S    N  +   S  S+   +S   S+      
Sbjct: 998  SDSSNSS-------DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050

Query: 609  SVESSHLNVSGQVEIHLGDSLSSTKQPSNDSA-SVELNHTENEAQASKSENSQEPSSSVK 667
            S +SS+ + S         S SS    S+DS+ S + + + N + +S S +S + S S  
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110

Query: 668  EENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSN 727
              ++   S   N++    +    + +   NS      S  S   DS   S ++D   SS+
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 728  NSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELV 787
            +S   D+SN        SD    S  ++ + +  S +  +      SS +   + +++  
Sbjct: 1171 SSDSSDSSNSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226

Query: 788  KCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSAN 838
                S E+  +   ++  DS++   S  +  S DS  ++    D  + S N
Sbjct: 1227 DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 121/616 (19%), Positives = 245/616 (39%), Gaps = 24/616 (3%)

Query: 255  SNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQD 314
            SN S     +++ N   +SD++ +     +D++ +    S D      S+   S  +  D
Sbjct: 684  SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS-SD 742

Query: 315  ILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVLADETNLAVKGSFET 374
              + ++S  +     D  D   + N+ + S S  S     + +   +++++ +   S  +
Sbjct: 743  SSDSSDSSNSS----DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798

Query: 375  EESDGQSGQPAFCTSYQND-DPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVP 433
              SD  +   +  +S  +D D  N+  +SN+ D     +  + S  S S       ++  
Sbjct: 799  NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858

Query: 434  TEQKCDIDITFES-VPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSS 492
            ++     D +  S   N +D +   +SN   N   +   +N   +++  +     +S SS
Sbjct: 859  SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918

Query: 493  NVP--SESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQF 550
            N    SES    D  +   +S  S   ++++ +      +S   S  +  +   S  S  
Sbjct: 919  NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978

Query: 551  CENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSV 610
              NS+D+     +   S SSDSS    S    +      S  SN  D+S   S     S 
Sbjct: 979  SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD-----SSDSSNSSDSS--NSSDSSNSS 1031

Query: 611  ESSHLNVSGQVEIHLGDSLSSTKQPSNDSA-SVELNHTENEAQASKSENSQEPSSSVKEE 669
            +SS  + S         S SS    S+DS+ S + + + + + +S S +S E S S    
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091

Query: 670  NTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNS 729
            N+   S   +++    +    + +   +S +    S  S   DS  +S N+ D   S+ S
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSNSSDSSDSSES 1150

Query: 730  AEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKC 789
            ++   S+  S     SD    S  ++ +++  S +  +      SS +   + +++    
Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1210

Query: 790  LSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGY 849
              S ++  +   ++  DS+   +S  +  S DS+ ++  ++   +  ++ +   S D   
Sbjct: 1211 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD 1270

Query: 850  IQLMPATSTAFGNSNN 865
             Q      +  GN NN
Sbjct: 1271 SQ------SKSGNGNN 1280



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 119/613 (19%), Positives = 224/613 (36%), Gaps = 50/613 (8%)

Query: 161  SGQISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKST 220
            S   SD S S     + S S D+  +  + +    +    +  S  S     S     S+
Sbjct: 712  SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 221  TLSGPHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQV 280
              S    +  +    ++          N+ +   S+ S     + + +   +SD++ +  
Sbjct: 772  DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 281  PKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQA-LFDLFDYGKTKN 339
               + N+    ++S D   G  S+     ++         SD +  +   D  D  ++ N
Sbjct: 832  SSDSSNSSDSSDSS-DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890

Query: 340  NKNISQSISSQPMESNPSIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNAL 399
            + + S S +S   +S+ S   +D ++ +   S ++ ES   S       S  + D  ++ 
Sbjct: 891  SSDSSDSSNSSDSDSSDSSNSSDSSDSS--NSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948

Query: 400  KNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNS 459
             +SN+ D     D  N S  S S    +  ++  ++     D +  S     D +   NS
Sbjct: 949  DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS-----DSSDSSNS 1003

Query: 460  NAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEA 519
            +   +   +   +N   +          +S  S+  S+S    D  D   +S  S   ++
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063

Query: 520  NN-----ENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSE 574
            ++     ++   S  S    S D+S +   S  S    +S+D+     +   S SSDSS 
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSN 1122

Query: 575  VHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQ 634
               S           S  S+  D+S           +SS+ + S         S SS   
Sbjct: 1123 SSDS-----------SDSSDSSDSS-----------DSSNSSDSSDSSESSDSSDSSDSS 1160

Query: 635  PSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTP 694
             S+DS+      + + + +S S NS + S S    ++   S   +++    +    + + 
Sbjct: 1161 DSSDSSD-----SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215

Query: 695  VENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDT 754
              +S      S  S   +S   S ++D   SSN+S   D+S+        S D    S+ 
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD--------SSDSTSDSND 1267

Query: 755  ELTSAVSSINGEN 767
            E  S   S NG N
Sbjct: 1268 ESDSQSKSGNGNN 1280



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 97/479 (20%), Positives = 188/479 (39%), Gaps = 29/479 (6%)

Query: 376 ESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTE 435
           +S G     +  TS  N+   N   N+ N D  + +  +  S  S S    +  ++  ++
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565

Query: 436 QKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVP 495
              D D +  +  + +D +   +S++  +       ++  S  ++ +   + +  S +  
Sbjct: 566 SS-DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624

Query: 496 SESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSN 555
             S+ + D  D    S  S   ++N+ +   +  SS   +   S     S  S    +S+
Sbjct: 625 DSSKSESDSSDSDSKSDSS---DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681

Query: 556 DTVKLKINFHGSKSSDSSEVHKS--KIEINVLEPVMSQLSNCQDNSCLQSEILPVSVESS 613
           D+     +   S SS+SSE   S    + +  +   S  SN  D+    S     S  SS
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 614 HLNVSGQVEIHLGDSLSSTKQPSNDSA-------------SVELNHTENEAQASKSENSQ 660
             + S         S SS    S+DS+             S + N + N + +S S NS 
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 661 EPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLP-------PESVCSSVGDS 713
           + S+S    ++   S   ++N    + +        +S S          +S  S+  DS
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 714 HPESQNTDDKPSSNNSAEIDASNI-VSLKVIISDDPFVSSDTELTSAVSSINGENLPTII 772
              S ++D   SSN+S   D+S+   S     S D   SSD++ + + +S +  +     
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921

Query: 773 LSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNED 831
            SS + + + N+      +S ++  +   +   DS++   S  +  S DS  N++ + D
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS--NSSDSSD 978



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 108/541 (19%), Positives = 204/541 (37%), Gaps = 33/541 (6%)

Query: 161  SGQISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKST 220
            S   SD S S     + S S D+  + ++ +         +++S  S     S+S   S 
Sbjct: 791  SSDSSDSSNSS----DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846

Query: 221  TLSGPHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQV 280
            +  G  S   N  D +  +       +++     S+ S      E+ N   +SD++    
Sbjct: 847  SSDGSDSDSSNRSDSSNSSDSS----DSSDSSNSSDSSDSSDSNESSNSSDSSDSS---- 898

Query: 281  PKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNN 340
               +D++ ++   S D      S          D    ++S  +  +  D  D   + ++
Sbjct: 899  -NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS-DSSDSSNSSDS 956

Query: 341  KNISQSISSQPMESNPSIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALK 400
             N S S +S     + S   +D +N +   S ++ +S   S       S  + D  ++  
Sbjct: 957  SNSSDSSNSSDSSDSNSSDSSDSSNSS--DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014

Query: 401  NSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSN 460
            +SN+ D     D  N S  S S        +  +    D   + +S  + +  +   +S+
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074

Query: 461  AECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEAN 520
            +  +   +E   +  S+ +  +     +S SS+  S+S    D  D   +S  S   +++
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSNSSDSSDSSDSS 1133

Query: 521  NENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKI 580
            + +   S  SS       S     S  S    +S+D+     +   S SSDSS+   S  
Sbjct: 1134 DSSD--SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-- 1189

Query: 581  EINVLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSA 640
                     S  S+  D+S   S     S +SS  + S         S SS    S+DS+
Sbjct: 1190 ---------SDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238

Query: 641  -SVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSH 699
             S + + + N + +S S +S + +S   +E+      G   N    + +  EG+   +S 
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298

Query: 700  S 700
            S
Sbjct: 1299 S 1299



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 78/397 (19%), Positives = 147/397 (37%), Gaps = 18/397 (4%)

Query: 255  SNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQD 314
            S+ S     ++N N    S N+         +N ++   S D      S    S ++   
Sbjct: 921  SDSSESSNSSDNSNSS-DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979

Query: 315  ILEQTESDPAFQALFDLFDYGKTKNNKNISQSI-SSQPMESNPSIVLADETNLAVKGSFE 373
                  SD +  +  D  D   + N+ + S S  SS    S+ S   +D +N     S +
Sbjct: 980  SNSSDSSDSSDSS--DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN-----SSD 1032

Query: 374  TEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVP 433
            + +S   S       S  + D  N+  +S++ D     D  + S  S S +      +  
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092

Query: 434  TEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSSN 493
            +    D   + +S  + +  +   +S++  +   ++   +  S+++        NS  S+
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS-------NSSDSS 1145

Query: 494  VPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCEN 553
              SES    D  D   +S  S   ++++ +   S  SS       S     S  S    +
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSD 1203

Query: 554  SNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSVESS 613
            S+D+     +   S SSDSS+   S       +   S  S+   NS   S+    S  +S
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263

Query: 614  HLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENE 650
              N     +   G+  ++     +DS   + NH+ ++
Sbjct: 1264 DSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 261/1359 (19%), Positives = 476/1359 (35%), Gaps = 203/1359 (14%)

Query: 130  TAPASAELLTLPYLSGQF----TTPPSTGTQVTRPSGQISDPSRSYFVVVNHSQSQD--T 183
            T  AS  + T P +S +     TTP  T T +T  +   S P+ +  +VV  S + +  T
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGST 2515

Query: 184  VTTGEALNVIPGAQEKKAHASLM-----SPGRRKSESQRKSTTLSG---PHSTIRNFQDP 235
            + T   ++  P A  + +  S       SP    +E    +T+  G   P ST      P
Sbjct: 2516 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP 2575

Query: 236  NAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSI 295
                      + ++    LS   +   +    +   +S    A+      + P+E  TS+
Sbjct: 2576 LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSL 2635

Query: 296  DEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESN 355
               L     +  SE +    L  T  D                  +  S   S+    S 
Sbjct: 2636 TSILVSTMPVASSEAS---TLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERST 2692

Query: 356  P-SIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQE 414
            P + +L   T LA   +     +   +  P   ++  +  P  A   S     +R     
Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTS-----MRISTPS 2747

Query: 415  NFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQ 474
            + S   TSI       A              S+P         ++ A  +P  AE+ +  
Sbjct: 2748 DGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT------STEASSSPTTAEVTSMP 2801

Query: 475  MSTETE-----MAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGK 529
             ST +E      ++ +    ++S+        P     P+T+                  
Sbjct: 2802 TSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTT------------------ 2843

Query: 530  SSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVM 589
            S++  S  T+  G     S   E S     + ++     SS++S +  + ++ ++  PV 
Sbjct: 2844 STKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSI--PVT 2901

Query: 590  SQLSNCQDNSCLQSEILPVSVES-----------SHLNVSGQVEIHLGDSLSSTKQPSND 638
            +        +  +   +P+S  S           S + V+G     L  +   T+ P   
Sbjct: 2902 TSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTT 2961

Query: 639  SASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLG------GNANCEKVALTPPE- 691
            SA       E  +  + +E +  P S+  E  T   S+        ++    ++ TP + 
Sbjct: 2962 SA-------EASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADT 3014

Query: 692  GTPVENS---HSLPPESVCSSVGDSHPESQNT--DDKPSSNNSAEIDASNIVSLKVIISD 746
             TPV  S    S P  +  + +  S P   +T     P S     I  ++ +S   + S+
Sbjct: 3015 STPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSN 3074

Query: 747  DPFVSSDTELTSAVSSINGENLPTIILSSP----TKSPTKNAELV-KCLSSEETVGAVVY 801
             P V+S TE++S+ +   G ++P    S      T  P     +    +S+  T      
Sbjct: 3075 SPVVTS-TEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTS 3133

Query: 802  AEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIA----FSANVTPCVSKDGGYIQLMPA-T 856
              V  S     S  T  SE +++  +   +G         +    VS +   +   P  T
Sbjct: 3134 TPVTTSTEAHSSPTT--SEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDT 3191

Query: 857  STAFGNSNNILIATCVTDPTALGTSVSQSN-------VVVLPGNSAPMTAQPLPPQLQTP 909
            ST    S     +T     TA GTS+  S        +  +P ++ P+ +        TP
Sbjct: 3192 STPVTTSTEATSST-----TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTP 3246

Query: 910  PRSNS--VFAVNQAVSPNFSQGSAIIIASPVQ--------PVLQGMVGMIPVSVVGQNGN 959
              SN+    +   + SP  ++G+++  ++P +        PV    V     S +     
Sbjct: 3247 VDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA 3306

Query: 960  NFSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRN-----KPCIGKQVNNL---- 1010
            + STP         + P+ + +    P    S+ +  L N      P +  + + L    
Sbjct: 3307 DTSTPVTTYSQASSSPPIADGT--SMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP 3364

Query: 1011 VDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVP--FPEESIVPAAKPCHRRVLCFDS 1068
            VD+S          T V+  + A+     +E T++P   P E   P A           S
Sbjct: 3365 VDTS----------TPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSS 3414

Query: 1069 TTAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKIL 1128
                ++ T   ++ +V+ + E ++       SP ++     P++   +       +P  L
Sbjct: 3415 EVNTLSTTPVDSNTLVTTSTEASS-------SPTIAEGTSLPTSTTSEGSTPLSIMP--L 3465

Query: 1129 SKSESAISRHTTIR----------ETQSEKKVSPTEIVLESFHKATANKENELCSDVERQ 1178
            S +  A S  +T+            T S    SPT   + S   +TA + +   +++   
Sbjct: 3466 STTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS 3525

Query: 1179 KNP----ENSKLSIGQQNGGL------RSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVK 1228
              P    E S LS    +         ++  S A+LQ  T +  T S   + L+      
Sbjct: 3526 TTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT----- 3580

Query: 1229 DLKQEQTKSASSLITTEMLQDIQRHSSVSRLADSSDLPVP----RTPGSGAGEKH----- 1279
             +    T   SS  +T     + R + V+    S+  P P      P S   E       
Sbjct: 3581 -MLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTI 3639

Query: 1280 ---KEEPIDIIKAPSSRRFSEDSST-----SKVMVPPVTPD---LPACSPASETGSENSV 1328
                   + I +A ++     D+ST     ++V   PVTP+   +P  +P+   GS    
Sbjct: 3640 MPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSE--GSTPLT 3697

Query: 1329 NMAAHTLMILSRAAISRTT----SATPLKDNTQQFRASS 1363
             M   T  + S    + +T    ++TP+  +T+   +S+
Sbjct: 3698 TMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSA 3736



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 270/1418 (19%), Positives = 471/1418 (33%), Gaps = 186/1418 (13%)

Query: 51   LLSLFGKNLTTILNEYVAMKTKETSNNVPAIMSSLWKKLDHTLSQIRSMQSSPRFAGSQR 110
            L S+    L    +E   + T     ++P + +S       T +++ SM +S        
Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIP-VTTSTEASSSPTTAEVTSMPTSTP------ 2805

Query: 111  ARTRTGIAEIKRQRKLASQTAPASAELLTLPYLSGQFTTPPSTGTQVTRPSGQISDPSRS 170
            + T T +  +       + T  AS+E  TL       TTP  T T VT  +   S P+ +
Sbjct: 2806 SETSTPLTSMP-----VNHTPVASSEAGTLS------TTPVDTSTPVTTSTKASSSPTTA 2854

Query: 171  YFVVVNHSQSQD--TVTTGEALNVIPGAQEKKAHASLMS-----PGRRKSESQRKSTTLS 223
              +VV  S + +  T+ T   ++  P A  + +  S        P    +E     TT  
Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914

Query: 224  G---PHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQV 280
            G   P ST      P    +   + +  +    LS   +  +     +   +S    A+ 
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974

Query: 281  PKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNN 340
                 + P E  T +         +  SE +    L +T +D +                
Sbjct: 2975 TSMPISTPGERRTPLTSMSVSTMPVASSEAS---TLSRTPADTSTPVTTSTEASSSPTTA 3031

Query: 341  KNISQSISSQPMESNP-SIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNAL 399
            +     IS+    S P + +    T +A+  +     +   S  P   ++  +  P  A 
Sbjct: 3032 EGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAE 3091

Query: 400  KNSNNHDVLRQEDQ--ENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRG 457
              S       +           +T +   A  T   T       +T  +  + +     G
Sbjct: 3092 GTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEG 3151

Query: 458  NSNAECNPHCAELYTNQMSTETEMAIGIEKNSLS------------------------SN 493
             S     P         M   T + +  E ++LS                        ++
Sbjct: 3152 TSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTS 3211

Query: 494  VPSESQLQPDQPDIPITSF-VSLGCEANNENLILS----------GKSSQLLSQDTSLTG 542
            +P+ +   P +   P+TS  VS    A++E  ILS            S++  S   +  G
Sbjct: 3212 IPTST---PSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEG 3268

Query: 543  KPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQ 602
                 S   E S     + ++     SS++S +  +  + +      SQ S+        
Sbjct: 3269 TSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS--SPPIAD 3326

Query: 603  SEILPVSVESSH----LNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSEN 658
               +P S  S       N+S      +    S+      D+++     TE     + +E 
Sbjct: 3327 GTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEG 3386

Query: 659  SQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPES----VCSSVGDSH 714
            +  P+SS  E  T   S+        V+ TP   + V    + P +S      S+   S 
Sbjct: 3387 TSIPTSSPSEGTTPLASM-------PVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS 3439

Query: 715  PESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILS 774
            P        P+S  S      +I+ L    S  P  SS+    S +S+   +    +  S
Sbjct: 3440 PTIAEGTSLPTSTTSEGSTPLSIMPL----STTPVASSE---ASTLSTTPVDTSTPVTTS 3492

Query: 775  SPTKSPTKNAELVKCLSSEETVGAVVYAEVGDS----ASMEQSLLTFKSEDSAVNNTQNE 830
            SPT S    AE+    +S    G+     +  S    AS E S L+    DS    T + 
Sbjct: 3493 SPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSS 3552

Query: 831  DGIAFSANV--------TPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSV 882
               +  A +        TP  S+    +  M  +ST   +S     +T   D +   T+ 
Sbjct: 3553 QASSSPATLQVTTMRMSTP--SEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTS 3610

Query: 883  SQSNVVVLPGN--SAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQP 940
            +QSN    P    + PM+    P ++ TP     V   +  +S      S + + +    
Sbjct: 3611 TQSNSTPTPPEVITLPMST---PSEVSTPLTIMPVSTTSVTIS-EAGTASTLPVDTSTPV 3666

Query: 941  VLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLR-- 998
            +    V   PV+  G               MP+  P    S P   +P  + +       
Sbjct: 3667 ITSTQVSSSPVTPEGTT-------------MPIWTP-SEGSTPLTTMPVSTTRVTSSEGS 3712

Query: 999  --NKPCI--GKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVP---FPEES 1051
              + P +     V    ++   S    +    VS     + LG     +T P   FPE S
Sbjct: 3713 TLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESS 3772

Query: 1052 I--VPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNA------VSFPNLDSPNV 1103
               +P+           + +++P    +G     +S   ER+       +S  ++ SP+ 
Sbjct: 3773 TPSIPSVYTSMSMTTASEGSSSP-TTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSE 3831

Query: 1104 SSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKA 1163
            +STL  P       +   P L    + S S  +  TTIR + + ++ +P   +L S    
Sbjct: 3832 ASTLSTPPG-----DTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLP 3886

Query: 1164 TANKENELCS----DVERQKNPENSKLS------IGQQNGGLRSEKSIASLQEMTKKQGT 1213
            T+     + S    D      P     S          +  + +E S             
Sbjct: 3887 TSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPV 3946

Query: 1214 SSNNKNVL-----SVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSS--------VSRLA 1260
            +S+  +V      +V T V    +  T S SS  TT      +  ++        ++ + 
Sbjct: 3947 TSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVT 4006

Query: 1261 DSSDLPVPRTPGSG----------AGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVT 1310
             S+    PRT   G              H    +       S   S  S+ +   +PP  
Sbjct: 4007 MSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTF 4066

Query: 1311 PDLPACSPASETGSENSVNMAAHTLMILSRAAISRTTS 1348
            P   + +P + + S  +VN  A T M       +RTTS
Sbjct: 4067 PPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTS 4104



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 275/1351 (20%), Positives = 440/1351 (32%), Gaps = 251/1351 (18%)

Query: 132  PASAELLTLPYLSGQFTTPPSTGTQVTRPSGQISDPSRSYFVVVNHSQSQDTVTTGEALN 191
            P S  L+    +S   TTP  T T VT  +   S P+ S         S  T T GE   
Sbjct: 871  PVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTS------EGTSMPTSTPGEGST 924

Query: 192  VIPGAQEK-----KAHASLMS--------PGRRKSESQRKSTTLSG---PHSTIRNFQDP 235
             +    +       + A  +S        P    +E+    TT  G   P ST      P
Sbjct: 925  PLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTP 984

Query: 236  NAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPTEPETSI 295
                     ++ N+    LS   +        +   +S    A+      + P+E  T +
Sbjct: 985  LTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPL 1044

Query: 296  DEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQPMESN 355
                 +P    M   +    L  T +D +                   SQ+ SS      
Sbjct: 1045 TR---MPVSTTMVASSETSTLSTTPADTSTPV-------------TTYSQASSSS----- 1083

Query: 356  PSIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQEN 415
                 AD T++                     T  +   PL ++  S    V  +    +
Sbjct: 1084 ---TTADGTSMPTS------------------TYSEGSTPLTSVPVSTRLVVSSEASTLS 1122

Query: 416  FSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQM 475
             + + TS                 I +T  +  + +     G S     P         M
Sbjct: 1123 TTPVDTS-----------------IPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASM 1165

Query: 476  STETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLS 535
               T + +  E N+LS+  P +S+ Q           V+   EA++        ++++ S
Sbjct: 1166 PVSTTLVVSSEANTLST-TPVDSKTQ-----------VATSTEASS-----PPPTAEVTS 1208

Query: 536  QDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNC 595
              TS  G         E S     + +      SS++S +  S ++ +   PV +     
Sbjct: 1209 MPTSTPG---------ERSTPLTSMPVRHTPVASSEASTLSTSPVDTST--PVTTSAETS 1257

Query: 596  QDNSCLQSEILPVSV--ESSHLNVSGQVEIHLGDS--LSSTKQPSNDSASVELNHTENEA 651
               +  +   LP S   E S L  S  V   L  S   S+      D+    +   E  +
Sbjct: 1258 SSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSS 1317

Query: 652  QASKSENSQEPSSSVKEENTIFLSLGGNAN-CEKVALTPPEGTPVENSHSLPPES-VCSS 709
              + +E +  P+S+  E  T   S+  N       A++    TPV+NS  +   +  CSS
Sbjct: 1318 SPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSS 1377

Query: 710  VGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLP 769
                 P +      P+SN S     + + S+ V  S  P VSS+    SA       + P
Sbjct: 1378 -----PTTSEGTSMPNSNPSE--GTTPLTSIPV--STTPVVSSEASTLSATPV--DTSTP 1426

Query: 770  TIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDS----ASMEQSLLTFKSEDSAVN 825
                +  T SPT  AE +   +S  + G      +  S    A+ E S L+    DS   
Sbjct: 1427 GTTSAEATSSPT-TAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDS--- 1482

Query: 826  NTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQS 885
            N+      A S++ T             PA  T+   S     +T +T      T+V+ S
Sbjct: 1483 NSPVVTSTAVSSSPT-------------PAEGTSIAISTPSEGSTALTSIPVSTTTVASS 1529

Query: 886  NVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGM 945
             +  L    A +T+ P+    Q      +    +   S  +S+GS  + + PV  +L   
Sbjct: 1530 EINSLSTTPA-VTSTPVTTYSQASSSPTTADGTSMQTS-TYSEGSTPLTSLPVSTML--- 1584

Query: 946  VGMIPVSVVGQNGNNFSTPP----------------------RQVLHMPLTAPVCNRSIP 983
                   VV    N  ST P                         +  P        SIP
Sbjct: 1585 -------VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIP 1637

Query: 984  QFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEET 1043
                P  S +A  L   P         VDS+   +      TEVS           +E T
Sbjct: 1638 VSTTPVASPEASTLSTTP---------VDSNSPVI----TSTEVSSSP------TPAEGT 1678

Query: 1044 TVPFP--EESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNA-------VS 1094
            ++P     E   P      R      S  + ++ T   N   V+ + E  +        S
Sbjct: 1679 SMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTS 1738

Query: 1095 FPNLDSPNVSST----LKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKV 1150
             PN  +P+  +T    +   +   +  E        I + +    S   T   T +E   
Sbjct: 1739 MPN-STPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTS 1797

Query: 1151 SPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKSIASLQEMTKK 1210
             PT  + E     T+   +          N E S LS    +       S A     T  
Sbjct: 1798 IPTSTLSEGMTPLTSTPVSHTL-----VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA 1852

Query: 1211 QGTS---------SNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLAD 1261
            +GTS         S     + V T      +  T S +  +T+  +    + SS    AD
Sbjct: 1853 EGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTAD 1912

Query: 1262 SSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASE 1321
             S +P   TP  G        P+      SS   +  ++ +    P  T    + SP + 
Sbjct: 1913 GSSMPT-STPREGR-PPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTA 1970

Query: 1322 TG--------SENSVNMA----AHTLMILSRAAISRTT---SATPLKDNTQQFRASSRST 1366
             G        SE S  +     + TL++ S A+   TT   ++TP   +T+   +SS +T
Sbjct: 1971 DGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE--GSSSPTT 2028

Query: 1367 TKKRKIEELDERERNS----RPSSKNLTNSS 1393
                 I+     ER +     P S  L  SS
Sbjct: 2029 AGGTSIQTSTPSERTTPLAGMPVSTTLVVSS 2059



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 154/806 (19%), Positives = 285/806 (35%), Gaps = 114/806 (14%)

Query: 631  STKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENT----IFLSLGGNANCE--- 683
            +T + ++DS ++  + TE+ +  +  E +  P S+  EE+      F+S     + E   
Sbjct: 117  TTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYT 176

Query: 684  ----KVALTPP--EGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNI 737
                KV ++ P    T   +S + P  +      +S   +  T    S+   A  +A  +
Sbjct: 177  SLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITL 236

Query: 738  VSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEE--- 794
            ++  V IS    +S+  + +S+ ++  G +L     S  +   T+    V  + S E   
Sbjct: 237  LTTPVEISTPVTISA--QASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEAST 294

Query: 795  --TVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDG----IAFSANVTPCVSKDGG 848
              T  A     V  S     S  T  +E +++  +   +G     +  A+  P  + +  
Sbjct: 295  LSTTPAATNIPVITSTEASSSPTT--AEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMS 352

Query: 849  YIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVV--LPGNSAPMTAQPLPPQL 906
             + + P  ++         + T  T+P++L T+   ++++   L   S P+T  P+   L
Sbjct: 353  TLSITPVDTST--------LVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTIL 404

Query: 907  ---------QTPPRSNSVF---AVNQAVSPNFSQGSAIIIASPVQ---PVLQGMVGMIPV 951
                      T P  +  F   A   + SP  ++ ++I  ++P +   P+    V   PV
Sbjct: 405  VASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPV 464

Query: 952  SVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFPVP--PKSQKAQGLRNKPCIGKQVNN 1009
            +      +N ST P        T+   + S P   V   P S  ++G  + P     V+ 
Sbjct: 465  A--SSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEG--STPLTSMSVST 520

Query: 1010 LVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDST 1069
            +  +S  +        + S   + T     S  TT   PE + +P + P           
Sbjct: 521  MPVASSEASTLSTTPVDTSTP-VTTSSEASSSSTT---PEGTSIPTSTP--------SEG 568

Query: 1070 TAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILS 1129
            + P+ N       +VS   E +  S    DS    +T    S+++   E    P      
Sbjct: 569  STPLTNMPVSTRLVVSS--EASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMP------ 620

Query: 1130 KSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIG 1189
             + +   R TTI    +   VS T +                        + E S LS  
Sbjct: 621  -TSTYSERGTTI----TSMSVSTTLVA-----------------------SSEASTLSTT 652

Query: 1190 QQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQD 1249
              +       S  +    T  +GTS          T +  +    T  ASS  +T     
Sbjct: 653  PVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTP 712

Query: 1250 IQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPV 1309
            +   + V+   ++S  P      S       E    +   P S+     S  S +   P+
Sbjct: 713  VDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL 772

Query: 1310 -------TPDLPACSPASETGSENSVNMAAHTLMILSRAAISRTTSATPLKD--NTQQFR 1360
                   T    +CSP +  G+   ++  +    +L+   +S T   +P     +T    
Sbjct: 773  DTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVD 832

Query: 1361 ASSRSTTKKRKIEELDERERNSRPSS 1386
            ++S  TT           E  S P+S
Sbjct: 833  SNSPVTTSTEVSSSPTPAEGTSMPTS 858



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 171/850 (20%), Positives = 289/850 (34%), Gaps = 117/850 (13%)

Query: 638  DSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSL-----------GGNANCEKVA 686
            D+++     TE  +  + +E +  P+S   E  T   S+            G  +   V 
Sbjct: 2423 DTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVD 2482

Query: 687  LTPPEGTPVENSHS-LPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIIS 745
             + P  T  E S S    E +   +  +   S      P S        ++ +S   + S
Sbjct: 2483 TSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDS 2542

Query: 746  DDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVG 805
            + P V+S TE++S+ +S  G ++PT   S  +          K L+S E       A   
Sbjct: 2543 NSPVVTS-TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSE-------ASTL 2594

Query: 806  DSASMEQSL-LTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSN 864
             +  ++ S+ +T  +E S+   T  +  +  S       S     +  MP  S+     +
Sbjct: 2595 STTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLS 2654

Query: 865  NILIATCVTDPTALGTSVSQ--------------------SNVVV---LPGNSAPMTAQP 901
               + T     T+ GTS S                     +N++V   L  NS   T   
Sbjct: 2655 TTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST 2714

Query: 902  LPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQ---PVLQGMVGMIPV-----SV 953
             P    TP  +++      + SP  ++G+++ I++P     P+   +V  +PV     S 
Sbjct: 2715 TPVDTSTPVTTSA----EASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEAST 2770

Query: 954  VGQNGNNFSTP---PRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNL 1010
            V     + S P     +    P TA V +      P    S+ +  L + P     VN+ 
Sbjct: 2771 VSTTAVDTSIPVTTSTEASSSPTTAEVTS-----MPTSTPSETSTPLTSMP-----VNHT 2820

Query: 1011 VDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTT 1070
              +S  +        + S   + T     S  TT    E  +VP +       L    T+
Sbjct: 2821 PVASSEAGTLSTTPVDTS-TPVTTSTKASSSPTTA---EGIVVPISTASEGSTLL---TS 2873

Query: 1071 APVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSS---TLKPPSNNAIKREKEKPPLPKI 1127
             PV+ T   + +  + +      S P   S   SS   T +  S       +   PL  I
Sbjct: 2874 IPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSI 2933

Query: 1128 L-SKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNP----- 1181
            L S    A S  +T+  T  + +   T     S    TA   +   S    ++ P     
Sbjct: 2934 LVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMS 2993

Query: 1182 ---------ENSKLSIGQQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQ 1232
                     E S LS    +       S  +    T  +GT           T +  +  
Sbjct: 2994 VSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053

Query: 1233 EQTKSASSLITTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSS 1292
              T  A    +T     +  +S V    + S  P P    S     + E    +   P S
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113

Query: 1293 RRFSEDSSTSKVMVPPVTPDLPA-------CSPASETG--------SENS---VNMAAHT 1334
                  S+ S +   PV    P         SP +  G        SE S     M   T
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVST 3173

Query: 1335 LMILSRAAISRTTSATPLKDN---TQQFRASSRSTTKKRKIEELDERERNSRPSSKNLTN 1391
            ++++S  +   T SATP+  +   T    A+S +T +   I      E  +  +S  ++N
Sbjct: 3174 MLVVS--SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSN 3231

Query: 1392 SSIPMKKKKI 1401
            + +   +  I
Sbjct: 3232 TPVASSEASI 3241



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 135/692 (19%), Positives = 239/692 (34%), Gaps = 86/692 (12%)

Query: 743  IISDDPFVSSD--TELTSAVSSINGENLPTIILSSP--TKSPT--KNAELVKCLSSEETV 796
            + SD P VSS   T   S  +S +  +  T+  SS   T SPT  +  ++     SEE++
Sbjct: 98   VTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESI 157

Query: 797  GAVV-YAEVGDSASMEQ-SLLTFKSEDSAVNNTQNEDGIAFSANVTP--------CVSKD 846
             + + +       S E  + LT+K + S    T  +   A S+  TP          S+ 
Sbjct: 158  SSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQ---ASSSPTTPESTTIPKSTNSEG 214

Query: 847  GGYIQLMPATSTAFGNSNNILIATC---VTDPTALGTSVSQSNVVVL---------PGNS 894
               +  MPA++    +S  I + T    ++ P  +    S S               G S
Sbjct: 215  STPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGS 274

Query: 895  APMTAQPLPPQL----------QTPPRSNS--VFAVNQAVSPNFSQGSAI---------- 932
             P+T  PL   L           TP  +N   + +   + SP  ++G++I          
Sbjct: 275  TPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGST 334

Query: 933  -IIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFPVPPKS 991
             + ++P   +      M  +S+   + +   T   +   +P TA   +           S
Sbjct: 335  PLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTL-----S 389

Query: 992  QKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVPF--PE 1049
            + +  L N P     V +   S+  ++   + KT V+  S A+     +E+T++    P 
Sbjct: 390  EGSTPLTNMPVSTILVASSEASTTSTIPVDS-KTFVTTASEASSSPTTAEDTSIATSTPS 448

Query: 1050 ESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERN------AVSFPNLDSPNV 1103
            E   P              +T PVA+++  N      + +        A S P     N 
Sbjct: 449  EGSTPLTS--------MPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNS 500

Query: 1104 SSTLKPPSNNAIKREKEKPPLPKILSKSESAISRH----TTIRETQSEKKVSPTEIVLES 1159
              T  P   +          +P + S   S +S      +T   T SE   S T     S
Sbjct: 501  MPTSTPSEGSTPLTSMSVSTMP-VASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTS 559

Query: 1160 FHKATANKENELCSDVERQK----NPENSKLSIGQQNGGLRSEKSIASLQEMTKKQGTSS 1215
               +T ++ +   +++        + E S  S    +       S  +    T  +GTS 
Sbjct: 560  IPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM 619

Query: 1216 NNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGA 1275
                    GT +  +    T  ASS  +T     +  ++ V+   +++         S  
Sbjct: 620  PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679

Query: 1276 GEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTL 1335
               + E    +   P +      S  S +   PV    P  +    + S  + + A+   
Sbjct: 680  TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT 739

Query: 1336 MILSRAAISRTTSATPLKDNTQQFRASSRSTT 1367
               S  + +  TS    K       AS+ STT
Sbjct: 740  STPSEGS-TPLTSMPVSKTLLTSSEASTLSTT 770


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 280/1386 (20%), Positives = 472/1386 (34%), Gaps = 207/1386 (14%)

Query: 128  SQTAPASAELLTLP------YLSGQFTT-------PPSTGTQVTRPSGQISDPSRSYFVV 174
            S+ +P+S E  TLP       LS + TT       P +T +  T  S  +S+ S +    
Sbjct: 2972 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST---- 3027

Query: 175  VNHSQSQDTVTTG--EALNVIPGAQEKKA-HAS------LMSPGRRKSES--QRKSTTLS 223
             +HSQ   T TT   ++      +QE  A H+S       +SPG   + S  Q+ +T  S
Sbjct: 3028 -SHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHS 3086

Query: 224  GPHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKL--AENINKFLTSDNNIAQV- 280
             P  T       +        ++E +     S  SL   L  A + +  L  ++   Q  
Sbjct: 3087 SPGDTETTLLPDDTIT---SGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 3143

Query: 281  PKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNN 340
            P  +D  P+ P T+       P E+  +  +      +  S P           G+++ +
Sbjct: 3144 PSSSDTTPSPPGTT-----AAPVEVSTTYHS------RPSSTPTTHFSASSTTLGRSEES 3192

Query: 341  KNISQSISSQ-----PMESNPSIVLADETNLAVK-GSFETEESDGQSG-------QPAFC 387
              +  S  +      P  S  S+++ + T   +  GS ET    G +           F 
Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 3252

Query: 388  TSYQNDDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESV 447
            +S ++ D   +  ++ +  V  +    +    ST        T +P   +        S 
Sbjct: 3253 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ--ESTASHSS 3310

Query: 448  PNLNDFNQRGNSN--AECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQP 505
            P   D      S   +   P     ++   STET +   +  N+ +S +   S       
Sbjct: 3311 PGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTL---LPDNTTASGLLEASTPVHSST 3367

Query: 506  DIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFH 565
              P T+    G           G+S+   S   S    P+  +     ++  V+L    H
Sbjct: 3368 GSPHTTLSPAGSTTRQ------GESTTFQSWPNSKDTTPAPPT----TTSAFVELSTTSH 3417

Query: 566  GSKSS-----------------DSSEVHKSKIEINVL-EPVMSQLSNCQDNSCLQSEILP 607
            GS SS                 +S+ VH S +       P  S  S   + S       P
Sbjct: 3418 GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS-P 3476

Query: 608  VSVESSHL----NVSGQVE----IHLGDSLSSTKQPSNDSASVE--------------LN 645
             S ++ H       SG+ E     H   + + +  PS  SA VE               +
Sbjct: 3477 GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 3536

Query: 646  HTENEAQASKSENSQEPSSSVKEENTIFLS-------LGGNANCEKVALTPPEGTPVENS 698
              ++   + +SE S    SS     TI L        L G +    ++    E T +  S
Sbjct: 3537 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 3596

Query: 699  HSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS 758
             + P  S  S+   S P S  T   P+S  S+ +   +  S     S       D+  T 
Sbjct: 3597 TTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP 3656

Query: 759  AVS--SINGENLP----TIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQ 812
             +S  S    + P    T +L + T +   + E     SS  +    +      + S  Q
Sbjct: 3657 GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQ 3716

Query: 813  SLLTFKSEDSAVNNTQNEDGIAFSANVTPCV----SKDGGYIQLMPATSTAFGNSNNILI 868
               TF S   + + T   D    S  V        S       L PA+ST+ G       
Sbjct: 3717 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG---- 3772

Query: 869  ATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQ 928
                 + TA  T  + ++    P ++A    +      ++P  + +      + +   S+
Sbjct: 3773 -----ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 3827

Query: 929  GSAIIIASP---------VQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLT-APVC 978
             S I  +SP               G  G    S +       +T P       L+ A   
Sbjct: 3828 KSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTTPGLSEASTT 3886

Query: 979  NRSIPQFP---VPPKSQKAQGL-------RNKPCIGKQVNNLVDSSGHSVGCHAQKTEV- 1027
              S P+ P   + P S  + G+       R++P  G   + +  +S  + G   + T V 
Sbjct: 3887 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP--GSTHSTVSPASTTTPGLSEESTTVY 3944

Query: 1028 --SDKSIATDLGKKSEETTVPFPEESIVPAAKPC--HRRVLCFDSTT------------A 1071
              S  S  T +  +S  T+V   EE     ++P   H  +   DSTT            +
Sbjct: 3945 SSSPGSTETTVFPRSTTTSVR-REEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 4003

Query: 1072 PVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKS 1131
            P +   G    + + +    + +FP+  S +  + L P  +       E  P     S +
Sbjct: 4004 PASTQTGLPATLTTADLGEESTTFPS-SSGSTGTKLSPARSTTSGLVGESTPSRLSPSST 4062

Query: 1132 ESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQ 1191
            E+     +    + SEK  S T         AT +      S V  + +  +S+      
Sbjct: 4063 ETTTLPGSPTTPSLSEK--STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 4120

Query: 1192 NGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVG-TAVKDLKQEQTKSASS-------LIT 1243
                 S  +    QE T    +  + +  LS G T    L Q+ T   SS       L+ 
Sbjct: 4121 TAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 4180

Query: 1244 TEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSK 1303
             + +      +S    + +  L    TP S      +EE       PS    S D++ S 
Sbjct: 4181 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS----SSDTTPS- 4235

Query: 1304 VMVPPVTPDLP---ACSPASETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFR 1360
               PP T  +P   + +  S   S  + + +A +   L R+  S T  ++P    T  F 
Sbjct: 4236 ---PPSTTAVPVEVSTTYHSRPSSTPTTHFSASS-TTLGRSEESTTVHSSPGATGTALFP 4291

Query: 1361 ASSRST 1366
              S ++
Sbjct: 4292 TRSATS 4297



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 280/1409 (19%), Positives = 477/1409 (33%), Gaps = 199/1409 (14%)

Query: 128  SQTAPASAELLTLP------YLSGQFTT-------PPSTGTQVTRPSGQISDPSRSYFVV 174
            S+ +P+S E  TLP       LS + TT       P +T +  T  S  +S+ S +    
Sbjct: 1415 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST---- 1470

Query: 175  VNHSQSQDTVTTG--EALNVIPGAQEKK-AHAS------LMSPGRRKSES--QRKSTTLS 223
             +HSQ   T TT   ++      +QE   +H+S       +SPG   + S  Q+ +T  S
Sbjct: 1471 -SHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHS 1529

Query: 224  GPHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKL--AENINKFLTSDNNIAQV- 280
             P  T       +        ++E +     S  SL   L  A + +  L  ++   Q  
Sbjct: 1530 SPGDTETTLLPDDTIT---SGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 1586

Query: 281  PKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNN 340
            P  +D  P+ P T+       P E+  +  +      +  S P           G+++ +
Sbjct: 1587 PSSSDTTPSPPGTT-----AAPVEVSTTYHS------RPSSTPTTHFSASSTTLGRSEES 1635

Query: 341  KNISQSISSQ-----PMESNPSIVLADETNLAVK-GSFETEESDGQSG-------QPAFC 387
              +  S  +      P  S  S+++ + T   +  GS ET    G +           F 
Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 1695

Query: 388  TSYQNDDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESV 447
            +S ++ D   +  ++ +  V  +    +    ST        T +P   +        S 
Sbjct: 1696 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ--ESTASHSS 1753

Query: 448  PNLNDFNQRGNSN--AECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQP 505
            P   D      S   +   P     +++  STET +   +  N+ +S +   S       
Sbjct: 1754 PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL---LPDNTTASGLLEASTPVHSST 1810

Query: 506  DIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFH 565
              P T+    G           G+S+   S  +S    P+  +     ++  V+L    H
Sbjct: 1811 GSPHTTLSPAGSTTRQ------GESTTFQSWPSSKDTMPAPPT----TTSAFVELSTTSH 1860

Query: 566  GSKSS-----------------DSSEVHKSKIEINVL-EPVMSQLSNCQDNSCLQSEILP 607
            GS SS                 +S+ VH S +       P  S  S   + S       P
Sbjct: 1861 GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS-P 1919

Query: 608  VSVESSHL----NVSGQVE----IHLGDSLSSTKQPSNDSASVE--------------LN 645
             S ++ H       SG+ E     H   + + +  PS  SA VE               +
Sbjct: 1920 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTH 1979

Query: 646  HTENEAQASKSENSQEPSSSVKEENTIFLS-------LGGNANCEKVALTPPEGTPVENS 698
              ++   + +SE S    SS     TI L        L G +    ++    E T +  S
Sbjct: 1980 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 2039

Query: 699  HSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS 758
             + P  S  S+   S P S  T   P+S  S+ +   +  S     S       D+  T 
Sbjct: 2040 TTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP 2099

Query: 759  AVS--SINGENLP----TIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQ 812
             +S  S    + P    T +L + T +   + E     SS  +    +      + S  Q
Sbjct: 2100 GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ 2159

Query: 813  SLLTFKSEDSAVNNTQNEDGIAFSANVTPCV----SKDGGYIQLMPATSTAFGNSNNILI 868
               TF S   + + T   D    S  V        S       L PA+ST+ G       
Sbjct: 2160 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG---- 2215

Query: 869  ATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQ 928
                 + TA  T  + ++    P ++A    +      ++P  + +      + +   S+
Sbjct: 2216 -----ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 2270

Query: 929  GSAIIIASP---------VQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLT-APVC 978
             S I  +SP               G  G    S +       +T P       L+ A   
Sbjct: 2271 KSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2329

Query: 979  NRSIPQFP---VPPKSQKAQGL-------RNKPCIGKQVNNLVDSSGHSVGCHAQKTEV- 1027
              S P+ P   + P S  + G+       R++P  G   + +  +S  + G   + T V 
Sbjct: 2330 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP--GSTHSTVSPASTTTPGLSEESTTVY 2387

Query: 1028 --SDKSIATDLGKKSEETTVPFPEESIVPAAKPC--HRRVLCFDSTT------------A 1071
              S  S  T +  ++  T+V   EE     ++P   H  +   DSTT            +
Sbjct: 2388 SSSPGSTETTVFPRTPTTSVR-GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 2446

Query: 1072 PVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKS 1131
            P +   G    + + +    + +FP+  S +  +TL P  +       E  P     S +
Sbjct: 2447 PASTQTGLPATLTTADLGEESTTFPS-SSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2505

Query: 1132 ESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQ 1191
            E+     +    + SEK  S T         AT +      S V  + +  +S+      
Sbjct: 2506 ETTTLPGSPTTPSLSEK--STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 2563

Query: 1192 NGGLRSEKSIA-SLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDI 1250
                 S  +   S    T      S +  +L   T      QE T S SS  +T+     
Sbjct: 2564 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2623

Query: 1251 QRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVT 1310
               +++S   +S+      +PGS       +         +S R    + + +  + P +
Sbjct: 2624 GSTTALSFGQESTTF--HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS 2681

Query: 1311 PDLPACSPASETGSENSVNMAAHTLMILSRAAI-----SRTTSATPLKDNTQQFRASSRS 1365
               P     S T   +    + HT       A      S T   +P    T  F ASS +
Sbjct: 2682 STSPGLQGESTTFQTHPA--STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT 2739

Query: 1366 T--TKKRKIEELDERERNSRPSSKNLTNS 1392
            +  ++K  I         + PSS + T S
Sbjct: 2740 SGHSEKSTIFHSSPDASGTTPSSAHSTTS 2768



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 208/1103 (18%), Positives = 365/1103 (33%), Gaps = 128/1103 (11%)

Query: 351  PMESNPSIVLADETNLAVK-GSFETEESDGQSGQPA-------FCTSYQNDDPLNALKNS 402
            P  S PS+++ D T   +  GS ET    G + +P        F +S ++ D  +   + 
Sbjct: 596  PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 655

Query: 403  NNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAE 462
             +  V  +    +    ST        T +P   +          P     +    + + 
Sbjct: 656  TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASS 715

Query: 463  CNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNE 522
              P     ++   STET +   +  N+ +S +   S         P T+    G      
Sbjct: 716  LGPEYTTFHSRPGSTETTL---LPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQ- 771

Query: 523  NLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSS------------ 570
                 G+S+   S  +S   +P+  +     ++  V+     HGS SS            
Sbjct: 772  -----GESTTFHSWPSSKDTRPAPPT----TTSAFVEPSTTSHGSPSSIPTTHISARSTT 822

Query: 571  -----DSSEVHKSKIEINVLE-PVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIH 624
                 +S+  H S      +  P     S   + S         ++ S+    S  VE  
Sbjct: 823  SGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE-- 880

Query: 625  LGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLS-------LG 677
                   T   S+  ++   +  ++   + +SE S    SS     TI L        L 
Sbjct: 881  -----EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLL 935

Query: 678  GNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNI 737
            G +    ++    E T +  S + P  S  S+   S P S  T   P+S  S+ +   + 
Sbjct: 936  GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST 995

Query: 738  VSLKVIISDDPFVSSDTELTSAVS--SINGENLP----TIILSSPTKSPTKNAELVKCLS 791
             S     S       D+  T  +S  S    + P    T +L + T +   + E     S
Sbjct: 996  TSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 1055

Query: 792  SEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCV----SKDG 847
            S  +    +      + S  Q   TF S   + + T   D    S  V        S   
Sbjct: 1056 SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 1115

Query: 848  GYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQ 907
                L PA+ST+ G            + TA  T  + ++    P ++A    +      +
Sbjct: 1116 PRTTLSPASSTSPGLQG---------ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 1166

Query: 908  TPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTP-PR 966
            +P  + +      + +   S+ S I  +SP              S  G++  +  +P   
Sbjct: 1167 SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST 1226

Query: 967  QVLHMP--LTAPVCNRSIPQF---PVPPKSQKAQGLRNKPCIGKQ--VNNLVDSSGHSVG 1019
            ++  +P   T P  + +   F   P  P +  +        +G++   +     S HS  
Sbjct: 1227 EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV 1286

Query: 1020 CHAQKTE--VSDKSIATDLGKKSEETTVPFP---------EESIVPAAKPC--HRRVLCF 1066
              A  T   +S++S       +    T  FP         EE     ++P   H  +   
Sbjct: 1287 SPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTE 1346

Query: 1067 DSTT------------APVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNA 1114
            DSTT            +P +   G    + + +    + +FP+  S +  + L P  +  
Sbjct: 1347 DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS-SSGSTGTKLSPARSTT 1405

Query: 1115 IKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSD 1174
                 E  P     S +E+     +    + SEK  S T         AT +      S 
Sbjct: 1406 SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK--STTFYTSPRSPDATLSPATTTSSG 1463

Query: 1175 VERQKNPENSKLSIGQQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVG-TAVKDLKQE 1233
            V  + +  +S+           S  +    QE T    +  + +  LS G T    L Q+
Sbjct: 1464 VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ 1523

Query: 1234 QTKSASS-------LITTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDI 1286
             T   SS       L+  + +      +S    + +  L    TP S      +EE    
Sbjct: 1524 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF 1583

Query: 1287 IKAPSSRRFSEDSSTSKVMVPPVTPDLP---ACSPASETGSENSVNMAAHTLMILSRAAI 1343
               PS    S D++ S    PP T   P   + +  S   S  + + +A +   L R+  
Sbjct: 1584 QSWPS----SSDTTPS----PPGTTAAPVEVSTTYHSRPSSTPTTHFSASS-TTLGRSEE 1634

Query: 1344 SRTTSATPLKDNTQQFRASSRST 1366
            S T  ++P    T  F   S ++
Sbjct: 1635 STTVHSSPGATGTALFPTRSATS 1657



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 219/1150 (19%), Positives = 377/1150 (32%), Gaps = 162/1150 (14%)

Query: 48   PACLLSLFGKNLTTILNEYVAMKTKETSNNV-PAIMSSLWKKLDHTLSQIRSMQSSP--R 104
            P   LS        +  E  A +T   S +  P+  S+    ++ + +  RS  S+P   
Sbjct: 2199 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 2258

Query: 105  FAGSQRARTRTGIAEIKRQRKLASQTAPASAELLTLPYLSGQFTTPPST--GTQVTRPSG 162
            F  S      +  + I      AS T P+SA   T     G+ TT   +   T++T   G
Sbjct: 2259 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG--RGESTTSRISPGSTEITTLPG 2316

Query: 163  QISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRKSTTL 222
              + P  S      +S  +   TT    ++      +++  S   PG   S     STT 
Sbjct: 2317 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 2376

Query: 223  SGPHSTIRNFQDPNAFAVEKQMVIENAREKILSNK--SLQEKLAENINKFLTSDNNIAQV 280
             G           +  + E  +        +   +  +   + A       T D+  + +
Sbjct: 2377 PGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGL 2436

Query: 281  PKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNN 340
             +++   P  P ++     GLP+ +  +     D+ E++ + P+          G T   
Sbjct: 2437 TEESTAFPGSPASTQT---GLPATLTTA-----DLGEESTTFPSSS--------GSTGTT 2480

Query: 341  KNISQSISSQPM-ESNPSIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNAL 399
             + ++S +S  + ES PS +    T         T  S  +     F TS ++ D   + 
Sbjct: 2481 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST-TFYTSPRSPDATLSP 2539

Query: 400  KNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNS 459
              + +  V  +      S  S S       TA P            + P L+    R ++
Sbjct: 2540 ATTTSSGVSEE------SSTSHSQPGSTHTTAFPDST---------TTPGLS----RHST 2580

Query: 460  NAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEA 519
             +  +P   +      ST T         S SS   +++ L P       T+ +S G E+
Sbjct: 2581 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS-----TTALSFGQES 2635

Query: 520  NNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSK 579
               +       + L    T+ +G               V+     H S  S  + +  + 
Sbjct: 2636 TTFHSSPGSTHTTLFPDSTTSSG--------------IVEASTRVHSSTGSPRTTLSPA- 2680

Query: 580  IEINVLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDS 639
               +   P +   S         +   P    ++   V      H   S  ST      +
Sbjct: 2681 ---SSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHR--SPGSTPTTHFPA 2735

Query: 640  ASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSH 699
            +S    H+E       S ++   + S     T   S  G +   +++    E T +  S 
Sbjct: 2736 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT---SGRGESTTSRISPGSTEITTLPGST 2792

Query: 700  SLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSS------- 752
            + P  S  S+   S P S  T   P+S  S  +   +  S     S    VS        
Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2852

Query: 753  -DTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASME 811
               E T+  SS  G    T+   S T S  +  E     S   +    ++ E   ++ + 
Sbjct: 2853 LSEESTTVYSSSPGSTETTVFPRSTTTS-VRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2911

Query: 812  QSLLTF----KSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNIL 867
            +    F     S  + +  T     +   +   P  S   G   L PA ST  G      
Sbjct: 2912 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG-TTLSPARSTTSG------ 2964

Query: 868  IATCVTDPTALGTSVSQSNVVVLPGN---------SAPMTAQPLPPQLQTPPRSNSVFAV 918
                V + T    S S +    LPG+         S      P  P     P + +   V
Sbjct: 2965 ---LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 3021

Query: 919  NQAVSPNFSQ-GSAIIIASPVQPVLQGM-------------------VGMIPVSVVGQNG 958
            ++  S + SQ GS    A P      G+                    G    S +GQ  
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081

Query: 959  NNFSTPP--RQVLHMP---LTAPVCNRSIP--------QFPVPPKSQKAQGLRNKPCIGK 1005
              F + P   +   +P   +T+ +   S P           + P S  + GL+ +    +
Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 3141

Query: 1006 QVNNLVDSSGHSVGCHAQKTEVSD--------------KSIATDLGKKSEETTVPFPEES 1051
               +  D++    G  A   EVS                + +T LG+  E TTV     +
Sbjct: 3142 SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA 3201

Query: 1052 IVPAAKPCH--RRVLCFDSTTAPVAN-----TQGPNHKMVSQNKERNAVSFPNLDSPNVS 1104
               A  P      VL  + TT+P+++     T  P     +   E++   + +  SP+  
Sbjct: 3202 TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD-- 3259

Query: 1105 STLKPPSNNA 1114
            +TL P S  +
Sbjct: 3260 TTLSPASTTS 3269



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 40/143 (27%), Positives = 56/143 (39%), Gaps = 10/143 (6%)

Query: 89   LDHTLSQIRSMQSSPRFAGSQRARTRTGIAE---IKRQRKLASQTAPASAELLTLPYLSG 145
            L    +   S   SP    S  + T +G++E     R R  ++ T  A  +  T P LS 
Sbjct: 962  LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTT-AFPDSTTTPGLSR 1020

Query: 146  QFTT----PPSTGTQVTRPSGQISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKA 201
              TT    P ST T +   S   S PS+      + S S DT  +  +   +   QE   
Sbjct: 1021 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 1080

Query: 202  HASLMSPGRRKSESQRKSTTLSG 224
              S  +PG   +     STT SG
Sbjct: 1081 FHS--NPGSTHTTLFPDSTTSSG 1101


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 181/899 (20%), Positives = 318/899 (35%), Gaps = 130/899 (14%)

Query: 527  SGKSSQLLSQDTSLTGKPSKKSQFC--ENSNDTVKLKINFHGSKSSDSSEVHKSKIEINV 584
            +GKS+  +++ +  TG+P +KS     + S  + K   +FH S +S + +   S  E   
Sbjct: 235  TGKST--VTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKIT 292

Query: 585  LE----------PVMSQLSNCQDNSCLQSEILPVSVESSHLNVSG--------QVEIHLG 626
                        P  S+ +     +    ++L  + ++    +S         +   H G
Sbjct: 293  AASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGG 352

Query: 627  DSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVA 686
             + +    PS    +     T NE          E       ENT     G   N E  A
Sbjct: 353  RTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTA 412

Query: 687  -----LTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLK 741
                 L P E  P E+      E+   S  +     + T ++ ++ + AE          
Sbjct: 413  NENTTLFPAE--PTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHG----- 465

Query: 742  VIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVY 801
                  PF +  T  +SA S+ +GE  P +   + T SP +  E  +  ++E T      
Sbjct: 466  ---ERTPFANDKTTSSSAESTEHGERTP-LANENTTPSPAEPTENRERTANENTTP---- 517

Query: 802  AEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFG 861
            +  G + + E +    K+  S V  T+N +  A +   TP  ++     Q  P     F 
Sbjct: 518  SPAGPTENRE-TTANEKTTLSPVEPTENRETTA-NEKTTPSPAEPTENGQRTP-----FA 570

Query: 862  NSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQA 921
            N       +   +PT  G     +N    P  + P   +      +T P S +    N  
Sbjct: 571  NEKT---TSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTP-SPAEPTENGD 626

Query: 922  VSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRS 981
             +P  ++ +   +A P +   +            +   + S  P +  H   T P+ N +
Sbjct: 627  RTPLANEKTTPSLAEPTENGQR-------TPFANEKTTSSSAEPTE--HEERT-PLANEN 676

Query: 982  IPQFPVPPKSQKAQGLRNKPC---IGKQVNNLVDSSGHSVGCHAQKTE-----VSDKSIA 1033
                P  P   + +           G   N  + ++  +    A+ TE      ++K+ +
Sbjct: 677  TTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTS 736

Query: 1034 TDLGKKSEETTVPFP-EESIVPAAKPC---HRRVLCFDSTTAPVANTQGPNHKMVSQNKE 1089
            +           PF  E++   +A+P     R  L  ++TT   A   GP     ++N+E
Sbjct: 737  SPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPA---GP-----TENRE 788

Query: 1090 RNA----VSFPNLDSPNVSSTLK---PPSNNAIKREKEKPPL------PKILSKSESAIS 1136
            R A      FP   + N   T      PS        ++ PL      P +   +E+   
Sbjct: 789  RTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENG-K 847

Query: 1137 RHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLR 1196
            R     E  +     PT    E   +     EN   S  E  +N E +            
Sbjct: 848  RTPFANEKTTSSSAEPT----EHAERTPLANENTTSSPAEPTENRERT-----------A 892

Query: 1197 SEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSV 1256
            +EK+     E T+ + +++N K      T       E  +  ++  TT    +   H  +
Sbjct: 893  NEKTTQFPAEPTENRESTANEKT-----TPFPAEPTENREWTANENTTLSPAEPTEHEEM 947

Query: 1257 SRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMV-PPVTPDLPA 1315
            + L    +L  P   GS A     E P DI    +S   SE S+ S+++    ++    A
Sbjct: 948  TPLMVDENLQAPFRQGSCA-----ERPKDICATVASTTGSESSTASEIITSSTMSVSATA 1002

Query: 1316 CSPASETGSENSVNMA-------AHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTT 1367
             S AS T SE +++ A       A+  +  S A     T++    ++T  F   S +TT
Sbjct: 1003 SSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTT 1061



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 126/655 (19%), Positives = 219/655 (33%), Gaps = 79/655 (12%)

Query: 631  STKQPSNDSASVELNHTENEAQASKSENSQEPS--SSVKEENTIFLSLGGNANCEKVA-- 686
            +T  P+  + + +     NE   S S    E    + +  ENT     G   N E+ A  
Sbjct: 734  TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANE 793

Query: 687  -LTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIIS 745
              TP    P EN      E+   S       ++N D  P +N   E    ++        
Sbjct: 794  KTTPFPAEPTENRERTANENTTPSPAQP---TENGDRTPLAN---EKTTPSLAEPTENGK 847

Query: 746  DDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVG 805
              PF +  T  +SA  + + E  P +   + T SP +  E  +  ++E+T          
Sbjct: 848  RTPFANEKTTSSSAEPTEHAERTP-LANENTTSSPAEPTENRERTANEKTTQFPAEPTEN 906

Query: 806  DSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNN 865
              ++  +    F +E      T+N +  A + N T           L PA  T       
Sbjct: 907  RESTANEKTTPFPAEP-----TENREWTA-NENTT-----------LSPAEPTEHEEMTP 949

Query: 866  ILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPN 925
            +++   +  P   G+   +   +     S   +      ++ T    +S  +V+   S  
Sbjct: 950  LMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIIT----SSTMSVSATASST 1005

Query: 926  FSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCN-RSIPQ 984
             S  ++ I  S            IPVS        FST   +    P+TA +    S   
Sbjct: 1006 ASSTASEITMSSAA---------IPVSSTAYETIRFSTAVSE----PVTASILALESTLA 1052

Query: 985  FPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETT 1044
            F     +  +  + + P            S ++  C A  +E +  +I       SE+TT
Sbjct: 1053 FTTVSNTTTSSTVTSVPTTAS-----TSGSKNTTACEATMSETTIAAITA-----SEDTT 1102

Query: 1045 VPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVS 1104
            V      I   + P        D+TTA V+ T   N+ +       +    PN  S  ++
Sbjct: 1103 VSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTA--PNTASKTMT 1160

Query: 1105 STLKPPSNNAIK-------------REKEKPPLPKILSKSESAISRH---TTIRETQSEK 1148
            +  K  + + I                  + P       + +AIS     TT+    S  
Sbjct: 1161 TASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTA 1220

Query: 1149 KVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKSIASLQEMT 1208
              +P E    S    T+   +E          P     +  + + G  + ++  S  E+T
Sbjct: 1221 PPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVT 1280

Query: 1209 KKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLADSS 1263
                T+    +     TAV   K   T + S   T  ++      +SVS  A ++
Sbjct: 1281 TAMTTAMTTGS----ETAVVSTKAPVTTTQSGFSTATVMPAKTTTASVSTTASTT 1331



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 132/725 (18%), Positives = 256/725 (35%), Gaps = 91/725 (12%)

Query: 247  ENAREKILSNKSLQEKLAENI-NKFLTSDNNIAQVPKQTDNNPTEPE--TSIDEFLGLPS 303
            E+     L+N++     AE   N+  T++ N    P      PTE    T+ ++    P+
Sbjct: 665  EHEERTPLANENTTPSPAEPTENRERTANENTTPSPA----GPTENREMTANEKTTLFPA 720

Query: 304  EIHMSEEAIQDILEQTESDPAFQALFDLFDYG-KTKNNKNISQSISSQPMESNPSIVLAD 362
            E   + E   +  E+T S PA     +  + G +T      + S S++P E      LA+
Sbjct: 721  EPTENRERTAN--EKTTSSPA-----EPTENGQRTPFANEKTTSSSAEPTEHGERTPLAN 773

Query: 363  E-TNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQIST 421
            E T L+  G  E  E         F      +    A +N+        +  EN  +   
Sbjct: 774  ENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPA---QPTENGDRTPL 830

Query: 422  SIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEM 481
            + +K     A PTE                        N +  P   E  T+  +  TE 
Sbjct: 831  ANEKTTPSLAEPTE------------------------NGKRTPFANEKTTSSSAEPTEH 866

Query: 482  AIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEAN-NENLILSGKSSQLLSQDTSL 540
            A   E+  L++   + S  +P +      +  +    A   EN     + S    + T  
Sbjct: 867  A---ERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTEN-----RESTANEKTTPF 918

Query: 541  TGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSC 600
              +P++  ++  N N T+        ++ ++  E+    ++ N+  P        +  SC
Sbjct: 919  PAEPTENREWTANENTTLS------PAEPTEHEEMTPLMVDENLQAPF-------RQGSC 965

Query: 601  LQ--SEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSEN 658
             +   +I      ++    S   EI    ++S +   S+ ++S     T + A    S  
Sbjct: 966  AERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSST 1025

Query: 659  SQEP---SSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHP 715
            + E    S++V E  T  +     A    +A T    T   ++ +  P +  +S   +  
Sbjct: 1026 AYETIRFSTAVSEPVTASIL----ALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTT 1081

Query: 716  ESQNTDDKPS------SNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLP 769
              + T  + +      S ++     +++++ + +        +DT   S  +++   N  
Sbjct: 1082 ACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTL 1141

Query: 770  TIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQN 829
            ++I S+P+ +P   ++ +   S   T   +    +  +     S +T  SE    + T  
Sbjct: 1142 SVITSTPSTAPNTASKTMTTASKTTTTSTI--TSLPTTVFTTTSKITAGSEIPTASTTD- 1198

Query: 830  EDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVV 889
                    + T  +S       +  A STA         A+  T  +  G+  +  + V 
Sbjct: 1199 --------SATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTSTTGSENTGHHTVS 1250

Query: 890  LPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMI 949
                +   TA       +T   S S   V  A++   + GS   + S   PV     G  
Sbjct: 1251 SVPTTVFATASESSTGSETTRASTSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFS 1310

Query: 950  PVSVV 954
              +V+
Sbjct: 1311 TATVM 1315


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 208/1103 (18%), Positives = 365/1103 (33%), Gaps = 128/1103 (11%)

Query: 351  PMESNPSIVLADETNLAVK-GSFETEESDGQSGQPA-------FCTSYQNDDPLNALKNS 402
            P  S PS+++ D T   +  GS ET    G + +P        F +S ++ D  +   + 
Sbjct: 83   PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 142

Query: 403  NNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAE 462
             +  V  +    +    ST        T +P   +          P     +    + + 
Sbjct: 143  TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASS 202

Query: 463  CNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNE 522
              P     ++   STET +   +  N+ +S +   S         P T+    G      
Sbjct: 203  LGPEYTTFHSRPGSTETTL---LPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQ- 258

Query: 523  NLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSS------------ 570
                 G+S+   S  +S   +P+  +     ++  V+     HGS SS            
Sbjct: 259  -----GESTTFHSWPSSKDTRPAPPT----TTSAFVEPSTTSHGSPSSIPTTHISARSTT 309

Query: 571  -----DSSEVHKSKIEINVLE-PVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIH 624
                 +S+  H S      +  P     S   + S         ++ S+    S  VE  
Sbjct: 310  SGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE-- 367

Query: 625  LGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLS-------LG 677
                   T   S+  ++   +  ++   + +SE S    SS     TI L        L 
Sbjct: 368  -----EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLL 422

Query: 678  GNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNI 737
            G +    ++    E T +  S + P  S  S+   S P S  T   P+S  S+ +   + 
Sbjct: 423  GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST 482

Query: 738  VSLKVIISDDPFVSSDTELTSAVS--SINGENLP----TIILSSPTKSPTKNAELVKCLS 791
             S     S       D+  T  +S  S    + P    T +L + T +   + E     S
Sbjct: 483  TSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 542

Query: 792  SEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCV----SKDG 847
            S  +    +      + S  Q   TF S   + + T   D    S  V        S   
Sbjct: 543  SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 602

Query: 848  GYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQ 907
                L PA+ST+ G            + TA  T  + ++    P ++A    +      +
Sbjct: 603  PRTTLSPASSTSPGLQG---------ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 653

Query: 908  TPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTP-PR 966
            +P  + +      + +   S+ S I  +SP              S  G++  +  +P   
Sbjct: 654  SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST 713

Query: 967  QVLHMP--LTAPVCNRSIPQF---PVPPKSQKAQGLRNKPCIGKQ--VNNLVDSSGHSVG 1019
            ++  +P   T P  + +   F   P  P +  +        +G++   +     S HS  
Sbjct: 714  EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV 773

Query: 1020 CHAQKTE--VSDKSIATDLGKKSEETTVPFP---------EESIVPAAKPC--HRRVLCF 1066
              A  T   +S++S       +    T  FP         EE     ++P   H  +   
Sbjct: 774  SPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTE 833

Query: 1067 DSTT------------APVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNA 1114
            DSTT            +P +   G    + + +    + +FP+  S +  + L P  +  
Sbjct: 834  DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS-SSGSTGTKLSPARSTT 892

Query: 1115 IKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSD 1174
                 E  P     S +E+     +    + SEK  S T         AT +      S 
Sbjct: 893  SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK--STTFYTSPRSPDATLSPATTTSSG 950

Query: 1175 VERQKNPENSKLSIGQQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVG-TAVKDLKQE 1233
            V  + +  +S+           S  +    QE T    +  + +  LS G T    L Q+
Sbjct: 951  VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ 1010

Query: 1234 QTKSASS-------LITTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDI 1286
             T   SS       L+  + +      +S    + +  L    TP S      +EE    
Sbjct: 1011 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF 1070

Query: 1287 IKAPSSRRFSEDSSTSKVMVPPVTPDLP---ACSPASETGSENSVNMAAHTLMILSRAAI 1343
               PS    S D++ S    PP T   P   + +  S   S  + + +A +   L R+  
Sbjct: 1071 QSWPS----SSDTTPS----PPGTTAAPVEVSTTYHSRPSSTPTTHFSASS-TTLGRSEE 1121

Query: 1344 SRTTSATPLKDNTQQFRASSRST 1366
            S T  ++P    T  F   S ++
Sbjct: 1122 STTVHSSPGATGTALFPTRSATS 1144



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 40/143 (27%), Positives = 56/143 (39%), Gaps = 10/143 (6%)

Query: 89  LDHTLSQIRSMQSSPRFAGSQRARTRTGIAE---IKRQRKLASQTAPASAELLTLPYLSG 145
           L    +   S   SP    S  + T +G++E     R R  ++ T  A  +  T P LS 
Sbjct: 449 LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTT-AFPDSTTTPGLSR 507

Query: 146 QFTT----PPSTGTQVTRPSGQISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKA 201
             TT    P ST T +   S   S PS+      + S S DT  +  +   +   QE   
Sbjct: 508 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 567

Query: 202 HASLMSPGRRKSESQRKSTTLSG 224
             S  +PG   +     STT SG
Sbjct: 568 FHS--NPGSTHTTLFPDSTTSSG 588


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 77/314 (24%), Positives = 118/314 (37%), Gaps = 63/314 (20%)

Query: 625 LGDSLSSTKQPSNDSASV--ELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANC 682
           L  S+++T+  S+ +      +  TE  ++++ S +S    S+V    T   S   +   
Sbjct: 572 LTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITS---HFTT 628

Query: 683 EKVALTPPEGTPVENSHSLPPESVC----SSVGDSHPESQNTDDKPSSNNSAEIDASNIV 738
            + A+TP   TP   S  +P  S+     SSVG S   +  TD       S   D S + 
Sbjct: 629 SETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFP-----SIPTDISTLP 683

Query: 739 SLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGA 798
           +   IIS  P + S     +  SS+ G   PT+     T   T+N  +     S  +   
Sbjct: 684 TRTHIISSSPSIQS-----TETSSLVGTTSPTMSTVRMTLRITENTPI-----SSFSTSI 733

Query: 799 VVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATST 858
           VV  E                                +   TP V       Q  PA +T
Sbjct: 734 VVIPE--------------------------------TPTQTPPVLTSATGTQTSPAPTT 761

Query: 859 AFGNSNNILIATC--VTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVF 916
               S +   +T   +T  TAL T VS S V +   +S+ +   P  P LQT   S S F
Sbjct: 762 VTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEF 821

Query: 917 AVNQAVSPNFSQGS 930
                 + +F++GS
Sbjct: 822 -----TTESFTRGS 830


>gi|8923040 CDKN2A interacting protein [Homo sapiens]
          Length = 580

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 78/333 (23%), Positives = 131/333 (39%), Gaps = 47/333 (14%)

Query: 516 GCEANNENLILSGKSSQLLSQDTSLT-GKPSKKSQFCENSNDTVKLKINFHGSKSSDSSE 574
           G E  ++  ++ GK+S  + QD + T  K  + S   ENS+  +   I      S+ SS 
Sbjct: 136 GVEEPSKKRVIEGKNSSAVEQDHAKTSAKTERASAQQENSSTCIGSAIKSESGNSARSS- 194

Query: 575 VHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQ 634
                        + SQ S+  D          VS +SS  +VS QV        S  + 
Sbjct: 195 ------------GISSQNSSTSDGD------RSVSSQSSS-SVSSQVTTAGSGKASEAEA 235

Query: 635 PSNDSAS--VELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEG 692
           P    ++  V L  +   +  ++S +S++ S S K                K AL     
Sbjct: 236 PDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPK----------------KSALEGSSA 279

Query: 693 TPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSS 752
           +  ++S  +    + SS G S  E      KPSS  +A    ++  S +  +S     +S
Sbjct: 280 SASQSSSEIEVPLLGSS-GSSEVELPLLSSKPSS-ETASSGLTSKTSSEASVSSSVAKNS 337

Query: 753 DTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVV-----YAEVGDS 807
            +  TS ++  +  +  T +L+S + S    A L+   SS +T G++V      A V   
Sbjct: 338 SSSGTSLLTPKSSSSTNTSLLTSKSTSQVA-ASLLASKSSSQTSGSLVSKSTSLASVSQL 396

Query: 808 ASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVT 840
           AS   S  +     S   +  +E  + FS  +T
Sbjct: 397 ASKSSSQTSTSQLPSKSTSQSSESSVKFSCKLT 429



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 65/296 (21%), Positives = 114/296 (38%), Gaps = 59/296 (19%)

Query: 638 DSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVEN 697
           +S++VE +H +  A+  ++   QE SS+          +G     E        G   +N
Sbjct: 150 NSSAVEQDHAKTSAKTERASAQQENSSTC---------IGSAIKSESGNSARSSGISSQN 200

Query: 698 SHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEI-----DASNIVSLKVIISDDPFVSS 752
           S +   +   SS   S   SQ T       + AE       AS +  LK  ++     S+
Sbjct: 201 SSTSDGDRSVSSQSSSSVSSQVTTAGSGKASEAEAPDKHGSASFVSLLKSSVNSHMTQST 260

Query: 753 DTELTSAV---SSINGEN-----------LPTI-----------ILSSPTKSPTKNAELV 787
           D+   S     S++ G +           +P +           +LSS   S T ++ L 
Sbjct: 261 DSRQQSGSPKKSALEGSSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLT 320

Query: 788 KCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDG 847
              SSE +V + V     +S+S   SLLT KS                S N +   SK  
Sbjct: 321 SKTSSEASVSSSV---AKNSSSSGTSLLTPKSSS--------------STNTSLLTSKST 363

Query: 848 GYI--QLMPATSTAFGNSNNILIATCVTDPTALGT-SVSQSNVVVLPGNSAPMTAQ 900
             +   L+ + S++  + + +  +T +   + L + S SQ++   LP  S   +++
Sbjct: 364 SQVAASLLASKSSSQTSGSLVSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSE 419


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 86/377 (22%), Positives = 138/377 (36%), Gaps = 41/377 (10%)

Query: 1039 KSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANT-----QGPNHKMVSQNKERNAV 1093
            K+E T +    ++  P A    R  L  D++T  ++ T     QG +H  ++    R   
Sbjct: 9071 KTESTEMTITTQTGSPGATS--RGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPG 9128

Query: 1094 SFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPT 1153
              P L  P+V        + +        P+   L  S  + S   T   T     V  T
Sbjct: 9129 DVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSG--LVKTT 9186

Query: 1154 EIVLESFHKATANKEN------ELCSDVERQKNPENSKLSIGQQNGGLRSEKSIASLQEM 1207
            E++  S    T++  N      E+ +  E   + E  +++    +G      S      +
Sbjct: 9187 ELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSV 9246

Query: 1208 TKKQGTS------SNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLAD 1261
            T K  +S      + + NVL+   A  D  + QTKS  SL    M   I   +S    A 
Sbjct: 9247 TTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETS---SAT 9303

Query: 1262 SSDLPVPRTPGSGAGEKHKEEPID----IIKAPSSRRFSEDSS---TSKVMVPPVTPDLP 1314
                 +   P     E  + E I      I  P+    S D+S    +++  P    +  
Sbjct: 9304 EKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKEST 9363

Query: 1315 ACSPASETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEE 1374
              +   +TG   + +    TL   S A+   T SAT     TQ+F  S  +T   R  E+
Sbjct: 9364 DMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSAT-----TQRFPQSVVTTPMSRGPED 9418

Query: 1375 LD-----ERERNSRPSS 1386
            +        E+NS PSS
Sbjct: 9419 VSWPSPLSVEKNSPPSS 9435



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 186/1022 (18%), Positives = 376/1022 (36%), Gaps = 180/1022 (17%)

Query: 495  PSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQ-FCEN 553
            P  S    + P + I++  ++  +     +   G+ +   S   +  G PS ++Q F ++
Sbjct: 6135 PEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDS 6194

Query: 554  SNDTVK-------LKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEIL 606
               +V        LK +   ++ ++S       +      PV S L     +S +    +
Sbjct: 6195 ETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSV 6254

Query: 607  PVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPS--- 663
            P    +   ++   +E         T+ P N      L +T   ++A+   ++  PS   
Sbjct: 6255 PTPTLAKITDMDTNLE-------PVTRSPQN------LRNTLATSEATTDTHTMHPSINT 6301

Query: 664  -----SSVKEENTIFLSLGGNANCEK----VALTPPEGTPVENSHSLPPESVCSSVGDSH 714
                  +    N  + ++  +++  K    V +T   G  + ++ S+P  S    +    
Sbjct: 6302 AVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVST-SMPRSSAMKKI---- 6356

Query: 715  PESQNTDDK----PSSNNSAEIDASNIVSLKVIISDDPFVSSDTELT------SAVSSIN 764
             ES+ T         ++ S +I +S+  S    + D  F ++ TE++      S+ +SI 
Sbjct: 6357 -ESETTFSLIFRLRETSTSQKIGSSSDTST---VFDKAFTAATTEVSRTELTSSSRTSIQ 6412

Query: 765  GENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAV 824
            G   PT+   + T+S T  +       SEE     +  + G   +  Q  LT+   D+++
Sbjct: 6413 GTEKPTMSPDTSTRSVTMLSTFAGLTKSEE---RTIATQTGPHRATSQGTLTW---DTSI 6466

Query: 825  NNTQNEDGIAFS-----ANVTPCVSKDGGYIQ-LMPATSTAFGNSNNILIATCVTDPTAL 878
              +Q     A +      +++   S+   YI    P +     +S+++L    +T P+ +
Sbjct: 6467 TTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPV 6526

Query: 879  GTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAII----- 933
             T++ +S     P +   +T+ P    ++T     SV     ++ PN    S  I     
Sbjct: 6527 PTTLPESR----PSSPVHLTSLPTSGLVKTTDMLASV----ASLPPNLGSTSHKIPTTSE 6578

Query: 934  -IASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNR-----SIPQFPV 987
             I    +      + +  V        ++S+ P       +T+P+        +I    +
Sbjct: 6579 DIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSM 6638

Query: 988  PPKSQ-----------KAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDL 1036
            P  S+            A GL+          + + S+  S   H   T  ++ S  T++
Sbjct: 6639 PGSSEITRIEMESTFSLAHGLKGT----STSQDPIVSTEKSAVLHKLTTGATETS-RTEV 6693

Query: 1037 GKKSEETTVPFPEES---------IVPA-------AKPCHRRVLC-----FDSTT----- 1070
               S  T++P P+ S         ++P+        +  +  ++        ST+     
Sbjct: 6694 A-SSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFT 6752

Query: 1071 --APVANTQGPNHKMVSQ-----------NKERNAVSF---PNLDSPNVSSTL------- 1107
               P  +++   H M +Q           NK+   +S+   P+++  + SS+L       
Sbjct: 6753 LDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMT 6812

Query: 1108 KPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANK 1167
             PP ++ + +     P P     + S +    T+  +      SP  +   S    T ++
Sbjct: 6813 SPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDE 6872

Query: 1168 ENELC-----SDVERQKNPENSKLSIGQQNGGLR-SEKSIASLQEMTKKQGTSSNNKNVL 1221
            +         S      N E +    G Q+  L  SEK+ A+    T      +     +
Sbjct: 6873 DTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSM 6932

Query: 1222 SVGTAVKDLKQEQTKSAS-SLITTEMLQDIQRHSS----VSRLADSSDLPVPRTPGSGAG 1276
            SV +    +K+E T S +  L  T + Q+    +     +S +   +   V RT  + +G
Sbjct: 6933 SVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSG 6992

Query: 1277 EKHKEEPIDIIKAPSSRRFSEDSST---SKVMVPPVTPDLPACSPASETGSENSVNMAAH 1333
                      I  PS      + ST   +++   P   +    +  ++TG   S +    
Sbjct: 6993 RTS-------IPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTL 7045

Query: 1334 TLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERERNSRPSSKNLTNSS 1393
            TL   +  + ++T S       TQ+F  S  +T   R   ++  +   S PS +N   SS
Sbjct: 7046 TLDTSTTKSQAKTHSTL-----TQRFPHSEMTTLMSRGPGDMSWQ---SSPSLEN--PSS 7095

Query: 1394 IP 1395
            +P
Sbjct: 7096 LP 7097



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 202/1028 (19%), Positives = 366/1028 (35%), Gaps = 137/1028 (13%)

Query: 413  QENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNP----HCA 468
            Q + S +++ + +    T+ P+ +K     +  S+P +   +    +  E  P    H  
Sbjct: 6483 QLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLT 6542

Query: 469  ELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPD-QPDIPITS--FVSLGCEANNENLI 525
             L T+ +   T+M   +   SL  N+ S S   P    DI  T   + S      N    
Sbjct: 6543 SLPTSGLVKTTDMLASVA--SLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTT 6600

Query: 526  LSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVL 585
             S K S       S   K +       N  DT+        +    SSE+  ++IE   +
Sbjct: 6601 TSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIV------STSMPGSSEI--TRIE---M 6649

Query: 586  EPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELN 645
            E   S     +  S  Q  I  VS E S +             L      + +++  E+ 
Sbjct: 6650 ESTFSLAHGLKGTSTSQDPI--VSTEKSAV-------------LHKLTTGATETSRTEVA 6694

Query: 646  HTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALT---PPEGTPVENSHSLP 702
             +   +      +++ P  S +   ++ +SLG   +     +T   PP G+  + + +L 
Sbjct: 6695 SSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLD 6754

Query: 703  PESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDT-----ELT 757
              +  S  G     S  T + P S             +  +++ DP + S T     E T
Sbjct: 6755 TPTTSSRAGT---HSMATQEFPHSE------------MTTVMNKDPEILSWTIPPSIEKT 6799

Query: 758  SAVSSINGENLPTIILSSPTKSPTKNAELVKC---LSSEETVGAVVYAE-VGDSASMEQS 813
            S  SS+    +P+  ++SP  S T    +      ++S  T   V+  + +G S     S
Sbjct: 6800 SFSSSL----MPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTS 6855

Query: 814  LLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVT 873
                 S  S    T +ED  A  A + P  S     ++    TS+  G+ +++L  +  T
Sbjct: 6856 SPPNLSSTSHEILTTDEDTTAIEA-MHPSTSTAATNVE---TTSSGHGSQSSVLADSEKT 6911

Query: 874  DPTA-LGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAI 932
              TA + T+ +  +  V    S       +  +  T   +  +   + + + +FS  ++I
Sbjct: 6912 KATAPMDTTSTMGHTTVSTSMSVSSETTKIKRE-STYSLTPGLRETSISQNASFSTDTSI 6970

Query: 933  IIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQ-FPVPPKS 991
            +++     V  G    +  + V  +G      P Q   +P    +  R++ + F  P  +
Sbjct: 6971 VLSE----VPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLP---EISTRTMTRLFASPTMT 7023

Query: 992  QKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEES 1051
            + A+              +   +G S G  +Q T   D S      K     T  FP   
Sbjct: 7024 ESAE------------MTIPTQTGPS-GSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSE 7070

Query: 1052 IVPAAKPCHRRVLCFDSTTAPVANTQGPNH-KMVSQNKERNAVSFPNLDSPNVSSTLKPP 1110
            +                       ++GP      S     N  S P+L S   ++T  PP
Sbjct: 7071 MTTLM-------------------SRGPGDMSWQSSPSLENPSSLPSLLSLP-ATTSPPP 7110

Query: 1111 SNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENE 1170
             ++ +       PLP     + S ++    +  +      SP ++   S  + T  K+  
Sbjct: 7111 ISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTT 7170

Query: 1171 LCSDVERQKNPENSKLSIGQQNGGLRSEKSIASLQEMTKKQG----TSSNNKNVLSVGTA 1226
                V    N   S + I   + G  S  S  +  E +K       TS+     +++ T 
Sbjct: 7171 NTEAVHPSTNTAASNVEI--PSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTP 7228

Query: 1227 -VKDLKQEQTKSASSLI--TTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEP 1283
               +  + Q +S SSL     E    ++  S++   A  S++ +  T      E      
Sbjct: 7229 HFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSR 7288

Query: 1284 IDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSP---ASETGSENSVNMAAHTLMILSR 1340
              I  +  S    E S+T K++  P +P L   S     ++T    S + +  TL   + 
Sbjct: 7289 TSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTT 7348

Query: 1341 AAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERERNSRPSSKNLTNSSIPMKKKK 1400
             ++  T S       TQ+   S  +T   R   ++       RPSS  +  +S P  +  
Sbjct: 7349 PSLVITHSTM-----TQRLPHSEITTLVSRGAGDV------PRPSSLPVEETSPPSSQLS 7397

Query: 1401 IKKKKLPS 1408
            +     PS
Sbjct: 7398 LSAMISPS 7405



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 200/1010 (19%), Positives = 356/1010 (35%), Gaps = 139/1010 (13%)

Query: 496  SESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSN 555
            SES   PD P    ++  S    +    L  +G++++  S  + ++    K++ F   + 
Sbjct: 2989 SESMSYPD-PSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTA 3047

Query: 556  DTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQ-SEILPVSVESSH 614
             T +    F G   +            N+L  + +        S L  S+  P  + SS 
Sbjct: 3048 STSRKTSLFLGPSMARQP---------NILVHLQTSALTLSPTSTLNMSQEEPPELTSSQ 3098

Query: 615  LNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFL 674
                 +       +L+ T   +  S     + TE  A+   S  +   S SV  + ++  
Sbjct: 3099 TIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVE 3158

Query: 675  SLGGN-----------ANCEKVALTPPEGT---PVENSHSLPPESVCSSVGDSHPESQNT 720
            +  G            A        P E T   P   S   P  S    +  S   S + 
Sbjct: 3159 TTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISP 3218

Query: 721  DDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSP 780
            + + +  NS        V ++  +  +P     T L S  +SI+  +LPT   +SPTKSP
Sbjct: 3219 EIRSTVRNSPWKTPETTVPMETTV--EPVTLQSTALGSGSTSIS--HLPTGT-TSPTKSP 3273

Query: 781  TKN---AELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSA 837
            T+N    E V    S       +Y+  G      QSL T  S        ++  G    +
Sbjct: 3274 TENMLATERVSLSPSPPEAWTNLYS--GTPGGTRQSLATMSSVSLESPTARSITGTGQQS 3331

Query: 838  NVTPCVSKDGGYIQLMPATST---------AFGNSNNILIATCVTDPTALGTSVSQS--- 885
            +    VSK  G    M   ST         +   S+NIL    VT P ++ +   +S   
Sbjct: 3332 S-PELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNIL-EDPVTSPNSVSSLTDKSKHK 3389

Query: 886  -----NVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQP 940
                 +   +P  S  +  + +  + QT    +  ++   + S   S     + ASP   
Sbjct: 3390 TETWVSTTAIP--STVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASP--- 3444

Query: 941  VLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNK 1000
                +   + ++   Q  +  S P        LT P   ++     V   S   + LR  
Sbjct: 3445 ---DVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRAN 3501

Query: 1001 PCIGKQVNNLVDSSGH-SVGCHAQKTEVSDKSIA---------TDLGKKSEETTVPFPE- 1049
              +    +++  ++GH S      +  + D + A         T +G  S  TT P PE 
Sbjct: 3502 --VSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEV 3559

Query: 1050 -ESIVPAAKPCHRRVLCFD-----STTA--------------PVANTQGPNHKM-----V 1084
              S + +     RR    +     S+TA               VA + G    M     +
Sbjct: 3560 GMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFL 3619

Query: 1085 SQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRET 1144
            + + E +++S P+     + ++L  PS++A   + E     + LS S++  S   +    
Sbjct: 3620 ASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSR 3679

Query: 1145 QSEKKVSPTEIVLESFHKATANKE----NELCSDVERQKNPENSKLSI----GQQNGGLR 1196
                 +S  +I+  S+  ++   E    + + +D    K   N+ LS             
Sbjct: 3680 VQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWD 3739

Query: 1197 SEKSIASLQEMTK-KQGTSSNNKNVLS--VGTAVKDLKQEQTKSASSLITTEMLQD---- 1249
            + +S++S    T   QG ++  +  L   +  A   L        S++    M +     
Sbjct: 3740 TGRSLSSATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVT 3799

Query: 1250 IQRHSSVSRLADSSDLPVPRTPGSGAGE--KHKEEPIDII----KAP------------- 1290
              R    S+ A+ +   +P T  +  G+  +     +D+I    K P             
Sbjct: 3800 FSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALT 3859

Query: 1291 SSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSRAAI---SRTT 1347
            +  R + DS   K    P  P +     +    +   V  ++  L  L+   I   S TT
Sbjct: 3860 TEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTT 3919

Query: 1348 SATPLKDNTQQFRASSRSTTKKRKIEELDERERNSR--PSSKNLTNSSIP 1395
            S+   K +  +  A S STT K  I         +    SS++ ++S+IP
Sbjct: 3920 SSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIP 3969



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 78/359 (21%), Positives = 130/359 (36%), Gaps = 68/359 (18%)

Query: 598  NSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVEL-----NHTENEAQ 652
            NS  +  I  V+  SS L     ++I+L     +T  PS  S+  E      + T+ EA 
Sbjct: 3887 NSVSEDTIKEVTSSSSVLRTLNTLDINLESG--TTSSPSWKSSPYERIAPSESTTDKEAI 3944

Query: 653  ASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGD 712
               +   +        E+    ++  ++   K  LT P  T      S   +++ S    
Sbjct: 3945 HPSTNTVETTGWVTSSEHASHSTIPAHSASSK--LTSPVVTT-----STREQAIVSMSTT 3997

Query: 713  SHPESQNTDDKPSSNNSAEI-DASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTI 771
            + PES     +P+S  + E+ D S            P++  DT  T+  S          
Sbjct: 3998 TWPESTRARTEPNSFLTIELRDVS------------PYM--DTSSTTQTS---------- 4033

Query: 772  ILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNED 831
            I+SSP  +        +  SS+             S+ + QS+ +  S   A+    N  
Sbjct: 4034 IISSPGSTAITKGPRTEITSSKRI----------SSSFLAQSMRSSDSPSEAITRLSN-- 4081

Query: 832  GIAFSANVTPCVSKDGGYIQLMP-----ATSTAFGNSNNILIATCVTDPTALGTSVSQSN 886
                     P +++ GG I  M      ATS +    +    A+    P A     + S 
Sbjct: 4082 --------FPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSE 4133

Query: 887  VVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPN----FSQGSAIIIASPVQPV 941
               L       T+QP PP ++    S+S+  ++   SP+     SQG +     PV  V
Sbjct: 4134 KTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSV 4192



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 35/294 (11%)

Query: 754   TELTSAVSSINGENLPTIILS------SPTKSPTKNAELVKCLSSEET---VGAVVYAEV 804
             T L ++ S +N  ++PT+ILS      +P+ + +  AE    + +      V  VV   V
Sbjct: 11043 TSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLV 11102

Query: 805   GDSASMEQS----LLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAF 860
               S ++  +    L    SE     +     G+  S+ V     +  G +  +  +S A 
Sbjct: 11103 TSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAV 11162

Query: 861   GNSNNILIATCVTDP---TALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFA 917
              ++    +     +P   T+L T      +  +P  +   T Q L   L T   S +   
Sbjct: 11163 TSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAF 11222

Query: 918   VNQAVSPNFSQGSAIIIASP------VQPVLQGMVG--MIPVSVVGQNGNNFSTPPR--- 966
              N  V+ +  +     +A P      V P L    G     +S+V     + ST PR   
Sbjct: 11223 SNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTS 11282

Query: 967   QVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRN--KPCIGKQVNNLVDSSGHSV 1018
             +  H  L       ++P     P+++ +  +     P I   + +LV SSG  +
Sbjct: 11283 RFSHSELD------TMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDI 11330



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 104/554 (18%), Positives = 206/554 (37%), Gaps = 71/554 (12%)

Query: 428  FKTAVPTEQKCDIDITFESVPNLNDF--NQRGNSNAECNPHCAELYTNQMSTETEMAIGI 485
            F+T + TE       T   +P L D   ++  N+  E +   +E+ T   +TE      I
Sbjct: 5768 FETRIQTES------TSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTT-TTEVSRTEVI 5820

Query: 486  EKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQL-------LSQDT 538
              +  + + P  S++ P      IT   +      +  + ++ ++  +       L+ DT
Sbjct: 5821 TSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDT 5880

Query: 539  SLT----GKPSKKSQFCENSNDTVKLK-----INFHGSKSSDSSEVHKSKIEINVLEPVM 589
            S T    G  S  +Q   +S +T  +      +++    S + +    S + +  +    
Sbjct: 5881 SSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHS 5940

Query: 590  SQLSNCQDNSCLQSEILPVS--VESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHT 647
            S  S    +S   +  LPV+  + S        ++ H    L ++  PS  S S E+   
Sbjct: 5941 SLYSAVSGSS--PTSALPVTSLLTSGRRKTIDMLDTH--SELVTSSLPSASSFSGEI--- 5993

Query: 648  ENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALT------PPEGTPVENSHSL 701
                    SE S    +    ENT   ++G   +  K+  +      P   TP + + S+
Sbjct: 5994 ------LTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSM 6047

Query: 702  PPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVS 761
              +++ S+     PE++N D   +S  + E+   +   +    ++   V S   L +A  
Sbjct: 6048 MEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATE 6107

Query: 762  SINGENL---PTIILSS--PTKSPTKNAELVKCLSSEE----TVGAVVYAEVGDSASMEQ 812
                E     PT + +S   TKSP  + E     S+      +    +  + G S     
Sbjct: 6108 VSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSL 6167

Query: 813  SLLTFKSEDSAVN----NTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNN--- 865
              LT  +   A +    + + +D +   +  T  ++ D   +      S    NS +   
Sbjct: 6168 GQLTLDTSTIATSAGTPSARTQDFV--DSETTSVMNNDLNDVLKTSPFSAEEANSLSSQA 6225

Query: 866  -ILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQ------PLPPQLQTPPRSNSVFAV 918
             +L+ T  +  T+     S S++V +     P  A+       L P  ++P    +  A 
Sbjct: 6226 PLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLAT 6285

Query: 919  NQAVSPNFSQGSAI 932
            ++A +   +   +I
Sbjct: 6286 SEATTDTHTMHPSI 6299



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 83/414 (20%), Positives = 156/414 (37%), Gaps = 47/414 (11%)

Query: 550   FCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVS 609
             F  +  DTV      HG+  S +   + S  E++ L P+++ +S         S   P  
Sbjct: 10617 FFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVT-ISGTD-----TSTTFPTL 10670

Query: 610   VESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEE 669
              +S H   +    +      SST   +  + S    H E++A  S + +    +SS    
Sbjct: 10671 TKSPHETETRTTWLTHPAETSSTIPRTIPNFS----HHESDATPSIATSPGAETSSAIPI 10726

Query: 670   NTIFLSLGGNANCEKVALTPPEGTPVENSHSLP--------PESVCSSVGDSHPESQNTD 721
              T+      +   E +  +    +  + + ++P        P+++ S V  +HPE+Q + 
Sbjct: 10727 MTV------SPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLV--THPEAQTSS 10778

Query: 722   DKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS-AVSSINGENLPTI-ILSSPTK- 778
               P+S  S  +        +++ S    +++ T  T+ A+++  GE   T+ +++ P + 
Sbjct: 10779 AIPTSTISPAVS-------RLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQT 10831

Query: 779   SPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSAN 838
             SPT          S+      +    G  +S      T  +E   V         A  + 
Sbjct: 10832 SPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVIST 10891

Query: 839   VTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMT 898
               P ++   G  +  P+ +T+ G   +  I T    P   G       V  L  +S  +T
Sbjct: 10892 TIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGV------VTSLVTSSRAVT 10945

Query: 899   AQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVS 952
             +  +P  + T          + A S     GSA+     V P + GMV  +  S
Sbjct: 10946 STTIP--ILTFSLGEPETTPSMATSHGTEAGSAV---PTVLPEVPGMVTSLVAS 10994


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 168/839 (20%), Positives = 293/839 (34%), Gaps = 120/839 (14%)

Query: 612  SSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENT 671
            ++HL V+G      GD+   T+ P  + +S    H       S S  S   ++ +   +T
Sbjct: 2414 ATHLPVTGLSSASTGDT---TRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDT 2470

Query: 672  IFLSLG-------------GNANCEKVALTPPEGTPVENSHSLP-PESVCSSVGDSHP-- 715
              +S G                +  ++ +T P      ++  LP  ++  +S GD+ P  
Sbjct: 2471 SSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLP 2530

Query: 716  ----ESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSD----TELTSAVSSINGEN 767
                 S +T    S + ++   AS   +  + ++D    S+       +TS  S+  G+ 
Sbjct: 2531 VTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDT 2590

Query: 768  LPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNT 827
             P  +  + + S  +   L    +S  + G      V D++S      T  +    V NT
Sbjct: 2591 TPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSAS----TGHATPLPVTNT 2646

Query: 828  QN------------EDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDP 875
             +                A + + TP    D   +    ATS    +++++      + P
Sbjct: 2647 SSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLP 2706

Query: 876  TALGTSVSQSNVVVLPGNSAP------MTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQG 929
              + +S S  +   LP   A        T+ P+           +   V  A S +    
Sbjct: 2707 VTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHA 2766

Query: 930  SAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLT--APVCNRSIPQFPV 987
            + + + S +  V  G    +PV+         +TP      +P+T  + V        PV
Sbjct: 2767 TPLPLTS-LSSVSTGDTTPLPVTDTSSASTGQATP------LPVTSLSSVSTGDTTPLPV 2819

Query: 988  PPKSQKAQG-LRNKPCIGKQVNNL--------VDSSGHSVGCHAQKTEVSDKSIATDLGK 1038
               S  + G   + P       +          D+S  S G HA    V+D S A+    
Sbjct: 2820 TDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTG-HATLLPVTDTSSAS---- 2874

Query: 1039 KSEETTVPFPEESIVPA--AKPCH----RRVLCFDSTTAPVANTQ-------GPNH-KMV 1084
                T++P  + S +    A P H           +T  PV +T         P H    
Sbjct: 2875 IGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSP 2934

Query: 1085 SQNKERNAVSFPNLDSPNVS---STLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT- 1140
            S     +A   P  D+ + S   +T  P ++ +     +  PLP  ++   SA + HTT 
Sbjct: 2935 SSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLP--VTSPSSASTGHTTP 2992

Query: 1141 --IRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSE 1198
              + +T S      T + + S   A+         D       + S  S GQ      + 
Sbjct: 2993 LPVTDTSSASTGQATALPVTSTSSAST-------GDTTPLPVTDTSSASTGQATPLPVTS 3045

Query: 1199 KSIASLQEMTKKQGTSSNNKNV-LSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVS 1257
             S  S  + T    TS ++ +   +    V D     T  A+ L  T +       SSVS
Sbjct: 3046 LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSL-------SSVS 3098

Query: 1258 RLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACS 1317
               D++ LPV     +  G        D   A +    S   + +       T  LP   
Sbjct: 3099 -TGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTD 3157

Query: 1318 PASETGSE---------NSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTT 1367
             +S +  +         +SV+    T ++++ A+ + T  ATPL   T    AS+  TT
Sbjct: 3158 TSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPL-HVTSPSSASTGDTT 3215



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 185/844 (21%), Positives = 308/844 (36%), Gaps = 137/844 (16%)

Query: 609  SVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTE-----NEAQASKSENSQEPS 663
            SV + H       +     +  +T  P  D++SV   HT      + + AS  + +  P 
Sbjct: 1112 SVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPV 1171

Query: 664  ---SSVKEENTIFLSLGGNANCEKVALTP---PEGTPVENSHSLP-PESVCSSVGDSHPE 716
               SSV   +T  L +   ++      TP    + +     H+ P P +  SSV   H  
Sbjct: 1172 TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHAT 1231

Query: 717  SQ-----------NTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSS-DTE---LTSAVS 761
            S            +T   P ++ S+   AS   +  ++++D   VS+ DT    +TS  S
Sbjct: 1232 SLPVTIPSAASTGHTTPLPVTDTSS---ASTGQATSLLVTDTSSVSTGDTTPLPVTSTSS 1288

Query: 762  SINGENLPTIILSSPTKSPTKNAEL--VKCLSSEET-------VGAVVYAEVGDSASME- 811
            +  G   P + ++SP+ + T +A    V  LSS  T       V +   A  GD+  +  
Sbjct: 1289 ASTGHVTP-LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPV 1347

Query: 812  ---QSLLTFKSEDSAVNNTQNED-GIAFSANVTPCVSKDGGYIQLMPATS---TAFGNSN 864
                S+ T  +    V +  +   G A    VT   S   G    +P TS    + G++ 
Sbjct: 1348 TDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 1407

Query: 865  NILIATC------------VTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRS 912
             +L+               VTD +++ T  + S  V +P  SA  T    P  +     +
Sbjct: 1408 PLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIP--SAASTGHTTPLPVTDTSSA 1465

Query: 913  NSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMI-PVSVVGQNGNNFSTPPRQVLHM 971
            ++  A +  V+   S  +      PV        G + P+ V   +    S        +
Sbjct: 1466 STGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPS----SASTGHATPL 1521

Query: 972  PLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKS 1031
            P+T+     +    P+P  S  +    +   +      + D+S  S G H     V+  S
Sbjct: 1522 PVTSLSSASTGDTMPLPVTSPSSASTGDTTPL-----PVTDASSVSTG-HTTPLPVTSPS 1575

Query: 1032 IA----------TDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNH 1081
             A          TD    S+  T P P  S   A+      +   D+++A   +T     
Sbjct: 1576 SASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPV 1635

Query: 1082 KMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT- 1140
               S     +A    ++ SP+ +ST                PLP  ++ + SA + H T 
Sbjct: 1636 TNASSLSTGHATPL-HVTSPSSAST------------GHATPLP--VTSTSSASTGHATP 1680

Query: 1141 -------IRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNP----ENSKLSIG 1189
                      T    ++  T++   S  +AT      L S       P      S  S G
Sbjct: 1681 LPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 1740

Query: 1190 QQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTA-VKDLKQEQTKSASSLITTEMLQ 1248
              +  L ++ S AS  + T    T ++     SV TA    L      SAS+  TT +  
Sbjct: 1741 HASPLLVTDASSASTGQATPLPVTDTS-----SVSTAHATPLPVTGLSSASTDDTTRL-- 1793

Query: 1249 DIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPP 1308
                 + VS  +    +P+P T  S A       P+ +  A S       +ST      P
Sbjct: 1794 ---PVTDVSSASTGQAIPLPVTSPSSA-STGDTTPLPVTDASS-------ASTGDTTSLP 1842

Query: 1309 VTPDLPACSPASETGS-----ENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASS 1363
            VT  +P+ + +  T S      +SV+    T ++++ A+   T   TPL   T    AS+
Sbjct: 1843 VT--IPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPL-PVTDTNSAST 1899

Query: 1364 RSTT 1367
              TT
Sbjct: 1900 GDTT 1903



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 185/970 (19%), Positives = 331/970 (34%), Gaps = 129/970 (13%)

Query: 180  SQDTVTTGEALNVIPGAQE----KKAHASLMSPGRRKSESQRKSTTLSGPHSTIRNFQDP 235
            +Q+T TTGEAL   P        K A +   SP   +  SQ+ +T  S  HSTI +    
Sbjct: 568  TQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHS---- 623

Query: 236  NAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIAQVPKQTDNNPT----EP 291
                               ++ S QE  A        S     Q P+ T  + T     P
Sbjct: 624  -------------------TSTSPQESPA-------VSQRGHTQAPQTTQESQTTRSVSP 657

Query: 292  ETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTKNNKNISQSISSQP 351
             T         S    S  +  +I+ Q     +    F     G     +  + ++ + P
Sbjct: 658  MTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAP 717

Query: 352  MESNPSIVLADETNLAVKGSFETEES-----DGQSGQPAFCTSYQNDDPLNALKNSNNHD 406
               + ++  +  T+L+  G+     S      G  GQ    ++  + D   A+ +++  +
Sbjct: 718  SSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAE 777

Query: 407  VLRQEDQENFSQ-ISTSIQKKAFKTAVPTEQKCDIDITFESVP-NLNDFNQRGNSNAECN 464
                  Q   S+  S+  +  +  TA P+           S   + +    R +SN   +
Sbjct: 778  STEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRD 837

Query: 465  PHCAELYTNQMSTETEM-AIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNEN 523
             H  +  T  +S      AI +     SS VP            P  S  S       ++
Sbjct: 838  SHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFH--------PTLSEASTAGRPTGQS 889

Query: 524  LILSGKSSQLLSQDTSLTGKPSKKSQF-CENSNDTVKLKINFHGSKSS--------DSSE 574
               S  +S    Q+T+   + ++  +      +DT+ L      + S+         S+ 
Sbjct: 890  SPTSPSASP---QETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTG 946

Query: 575  VHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSVE-SSHLNVSGQVEIHLGDSLS--- 630
            +   + E + L P  S  +     + L S   P+ V  +S  +      +H+ D+ S   
Sbjct: 947  LTSPQTETHTLSPSGSGKTF---TTALISNATPLPVTYASSASTGHTTPLHVTDASSVST 1003

Query: 631  --STKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALT 688
              +T  P    +SV   HT        ++ S E +  V        S     +   + +T
Sbjct: 1004 GHATPLPVTSPSSVSTGHT---TPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVT 1060

Query: 689  PPEGTPVENSHSLPPESVCS-SVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDD 747
                    +   LP  S+ S S GD+ P         S+ ++  +  ++  S+    +  
Sbjct: 1061 DTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTT- 1119

Query: 748  PFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDS 807
            P   +DT   S+ S+ +  +LP    SS +   T    +    S          A  G +
Sbjct: 1120 PLPVTDT---SSASTGHATSLPVTDTSSVSTGHTTPLHVTDASS----------ASTGQA 1166

Query: 808  ASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNIL 867
              +  + L+  S              A + + TP +  D         +S + G++  + 
Sbjct: 1167 TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTD--------TSSASTGHATPLP 1218

Query: 868  IATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFS 927
                VTD +++ T  + S  V +P  SA  T    P  +     +++  A +  V+   S
Sbjct: 1219 ----VTDASSVSTDHATSLPVTIP--SAASTGHTTPLPVTDTSSASTGQATSLLVTDTSS 1272

Query: 928  QGSAIIIASPVQPVLQGMVGMI-PVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFP 986
              +      PV        G + P+ V   +    S        +P+T+     +    P
Sbjct: 1273 VSTGDTTPLPVTSTSSASTGHVTPLHVTSPS----SASTGHATPLPVTSLSSASTGDTMP 1328

Query: 987  VPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIA----------TDL 1036
            +P  S  +    +   +      + D+S  S G H     V+D S A          T L
Sbjct: 1329 LPVTSPSSASTGDTTPL-----PVTDASSVSTG-HTTPLHVTDASSASTGQATPLPVTSL 1382

Query: 1037 GKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNAVSFP 1096
               S   T P P  S   A+      +L  D+++A   +         S     +A S P
Sbjct: 1383 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLP 1442

Query: 1097 NLDSPNVSST 1106
             +  P+ +ST
Sbjct: 1443 -VTIPSAAST 1451



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 170/817 (20%), Positives = 280/817 (34%), Gaps = 126/817 (15%)

Query: 607  PVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTE-----NEAQASKSENSQE 661
            P S  + H             +  +T  P   ++S    HT      + + AS  + +  
Sbjct: 3286 PSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPL 3345

Query: 662  PSSSVKEENT-----IFLSLGGNANCEKVALTPPEG-TPVENSHSLP-PESVCSSVGDSH 714
            P +S    +T     + +++  +A+    +  P  G +     H+ P P +  SSV   H
Sbjct: 3346 PVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGH 3405

Query: 715  PESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTEL--TSAVSSINGENLPTII 772
                     P ++ S+ +   +   L V  +        T L  TS  S   G+  P ++
Sbjct: 3406 -----ATPLPVTSLSS-VSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLV 3459

Query: 773  LSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDG 832
              + + S      L    +S  + G      V D++S      T     S    +    G
Sbjct: 3460 TDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSL---SSVSTG 3516

Query: 833  IAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPG 892
                  VT   S   G+   +P T T+  ++ +      VTD ++  T  +    V +P 
Sbjct: 3517 DTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLP-VTDTSSASTGQATPLPVTIPS 3575

Query: 893  NSAPMTAQPLP-------------PQLQTPPRSNSVFAVNQAVSPNFSQGS----AIIIA 935
            +S+     PLP             P   T P S S   V      + S  S      ++ 
Sbjct: 3576 SSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLV 3635

Query: 936  SPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQ 995
            +    V  G    +PV+         +TP      +P+T      +    P+P  S  + 
Sbjct: 3636 TDASSVSTGHATPLPVTDASSASTGDTTP------LPVTDTSSASTGQATPLPVTSLSSV 3689

Query: 996  GLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPA 1055
               +   +      + D+S  S G HA    V+  S        S   T+P P  S   +
Sbjct: 3690 STGDTTPL-----PVTDASSASTG-HATPLPVTIPS------SVSTGDTMPLPVTS-PSS 3736

Query: 1056 AKPCHRRVL---------CFDSTTAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVS-- 1104
            A   H   L           D+T  PV +T        S    R+A   P  D+ + S  
Sbjct: 3737 ASTGHATPLPVTGLSSASTGDTTPLPVTDT--------SSASTRHATPLPVTDTSSASTD 3788

Query: 1105 -STLKPPSNNAIKREKEKPPLPKILSKSESAISRHTT---IRETQSEKKVSPTEIVLESF 1160
             +T  P ++ +        PLP  ++ + SA +  TT   + +T S      T + + S 
Sbjct: 3789 DTTRLPVTDVSSASTGHATPLP--VTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSR 3846

Query: 1161 HKATANKENEL-CSDVERQKN--------PENSKLSIGQQNGGLRSEKSIASLQEMTKKQ 1211
              A+      L  +D                 S +S G       +  S AS    T   
Sbjct: 3847 SSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVP 3906

Query: 1212 GTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQ-DIQRHSSVSRLADSSDLPVPRT 1270
             TS+++        +  D       +ASSL T       +   SS SR  D+S LPV  T
Sbjct: 3907 VTSTSS-------ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASR-GDTSTLPV--T 3956

Query: 1271 PGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNM 1330
              S A   H   P+ +            +S S V     TP      P ++T S ++   
Sbjct: 3957 DASSASTGH-ATPLPL------------TSLSSVSTGDTTP-----LPVTDTSSASTGQ- 3997

Query: 1331 AAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTT 1367
             A  L + S +++S T   TPL        +S  +T+
Sbjct: 3998 -ATPLPVTSLSSVS-TGDTTPLPVTIPSSASSGHTTS 4032


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 75/318 (23%), Positives = 127/318 (39%), Gaps = 39/318 (12%)

Query: 1040 SEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNAVSFPNLD 1099
            SEE   P  +ES    AKP    +    S    ++NT  P   ++  +      +FP+ D
Sbjct: 775  SEEPLSPQKDESSA-TAKPLGENLT---SQQKNLSNTPEP---IIMSSSSIAPEAFPSED 827

Query: 1100 SPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIVLES 1159
              N + + +   ++    +     +P++ S     +  H+ ++ T  EKKV P+ + L  
Sbjct: 828  LHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRT--EKKVLPSPLELSV 885

Query: 1160 FHKATANKENELCS----DVERQKNPENSKLSIGQQNGGLRSEKSIASLQEMTKKQGTSS 1215
            F + T NK NEL S    D +   + + +  S G +N     + S  S  E +    +S 
Sbjct: 886  FSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRN-KTHKQGSTQSRLETSHTSKSSE 944

Query: 1216 NNKNVLSVGTAVKDLKQEQTKSA---SSLITTEMLQDIQRHSSVSRLADSSDLPVPRTPG 1272
             +K+   +    +D +  + K+A   S  I  E    I+   S   ++ SS     + P 
Sbjct: 945  PSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPP- 1003

Query: 1273 SGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSV---- 1328
                   +EEP    + P  +        SK+  P +    P   P S   +  SV    
Sbjct: 1004 -------REEP----RVPPLK-----IQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGR 1047

Query: 1329 NMAAHTLM-ILSRAAISR 1345
            N  A TL  I +RA  +R
Sbjct: 1048 NTGARTLADIKARAQQAR 1065



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 87/389 (22%), Positives = 141/389 (36%), Gaps = 91/389 (23%)

Query: 494 VPSESQLQPDQPDIPITSFVSLGCEANNENLI--LSGKSSQLL-SQDTSLTGKPSKKSQF 550
           +P ES +Q +  +   TS     C+  N   I   S ++  L  S +      P    + 
Sbjct: 444 IPEESVIQEEIAEEVETSICE--CQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLES 501

Query: 551 CENSNDTVK----LKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEIL 606
           C   ND ++    +++   G   S   E          +  V+ QL  C       S + 
Sbjct: 502 CVMMNDVLETLPHIEVKIEGKSESPQEE----------MTVVIDQLEVCDSLIPSTSSMT 551

Query: 607 PVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSV 666
            VS ++ H      VE       +ST +    S+S+E     NE  A   E   +P   +
Sbjct: 552 HVS-DTEHKESETAVE-------TSTPKIKTGSSSLE-GQFPNEGIAIDMELQSDPEEQL 602

Query: 667 KEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQ-------- 718
            E          NA   + + +           S  PE  C+S+     E+Q        
Sbjct: 603 SE----------NACISETSFS-----------SESPEGACTSLPSPGGETQSTSEESCT 641

Query: 719 ----------------NTDDKPSSNNSAEIDASNIVSLKVIISDDPFVS-----SDTELT 757
                           NTD     N++ E   ++++S    IS  P +S     S+  LT
Sbjct: 642 PASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLT 701

Query: 758 SAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTF 817
           S  S ++  NLP   L+S T SP  +  L    SS       V + +  S +   S L  
Sbjct: 702 SEASPVS--NLP---LTSET-SPMSDLPLTSETSS-------VSSMLLTSETTFVSSLPL 748

Query: 818 KSEDSAVNNTQNEDGIAFSANVTPCVSKD 846
            SE S ++N+   + +A     +P VS++
Sbjct: 749 PSETSPISNSSINERMAHQQRKSPSVSEE 777


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 132/656 (20%), Positives = 222/656 (33%), Gaps = 93/656 (14%)

Query: 631  STKQPSNDSASVELNHTENEAQASKSENSQEPS--SSVKEENTIFLSLGGNANCEKVA-- 686
            +T  P+  + + +     NE   S S    E    + +  ENT         N E+ A  
Sbjct: 672  TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANE 731

Query: 687  -LTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIIS 745
              TP    P EN      E+   S       ++N D  P +N   E    ++        
Sbjct: 732  KTTPFPAEPTENRERTANENTTPSPAQP---TENGDRTPLAN---EKTTPSLAEPTENGK 785

Query: 746  DDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVG 805
              PF +  T  +SA  + + E  P +   + T SP +  E  +  ++E+T          
Sbjct: 786  RTPFANEKTTSSSAEPTEHAERTP-LANENTTSSPAEPTENRERTANEKTTQFPAEPTEN 844

Query: 806  DSASMEQSLLTFKSEDSAVNN-TQNEDGIAFSAN------VTPCVSKDGGYIQLMPATST 858
              ++  +    F +E +     T NE+     A       +TP  ++      L PA  T
Sbjct: 845  RESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEK---TTLSPAEPT 901

Query: 859  AFGNSN---NILIATCVTDPTALGTSVSQSNVVVLPGNSAPMT-AQPLPPQLQTP----P 910
              G      N        +PT  G     +N +  P  + P    + +  +  TP    P
Sbjct: 902  ENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKP 961

Query: 911  RSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLH 970
              +    VN+  +P           S  +P   G     P++    N N  ++P     H
Sbjct: 962  TEHGETTVNEDTTP-----------SSAEPTENGE--RTPLA----NENTTTSPTESTEH 1004

Query: 971  MPLTAPVCNRSIPQFPV------PPKSQKAQGLRNKPCIGKQV----NNLVDSSGHSVGC 1020
               TA       P  P       P  ++K      KP   +++    N     S      
Sbjct: 1005 GERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTE 1064

Query: 1021 HAQKTEVSDKSIA-TDLGKKSEETTVPFPEESIVPA-AKPCHRRVLCFDSTTAPVANTQG 1078
            H +KT ++++ I  +  G            E I P+ AKP           T     T  
Sbjct: 1065 HGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKP-----------TEHGERTTS 1113

Query: 1079 PNHKMVSQNKE----RNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESA 1134
            PN K+ S   E    R+  +  N+ +P  +  +K      +  EK    + ++  KS   
Sbjct: 1114 PNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEK----MTQVTEKSTE- 1168

Query: 1135 ISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGG 1194
                        EK  S TE    +  K T   E  +C+  +    PE    ++G  N  
Sbjct: 1169 ----------HPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLG--NTT 1216

Query: 1195 LRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDI 1250
            L +E   A ++     + T++  K +        D  +  T ++S L  TE+   +
Sbjct: 1217 LTTETIKAPVKSTENPEKTAAVTKTIKPSVKVTGD--KSLTTTSSHLNKTEVTHQV 1270



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 170/879 (19%), Positives = 305/879 (34%), Gaps = 132/879 (15%)

Query: 527  SGKSSQLLSQDTSLTGKPSKKSQFC--ENSNDTVKLKINFHGSKSSDSSEVHKSKIEINV 584
            +GKS+  +++ +  TG+P +KS     + S  + K   +FH S +S + +   S  E   
Sbjct: 173  TGKST--VTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKIT 230

Query: 585  LE----------PVMSQLSNCQDNSCLQSEILPVSVESSHLNVSG--------QVEIHLG 626
                        P  S+ +     +    ++L  + ++    +S         +   H G
Sbjct: 231  AASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGG 290

Query: 627  DSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVA 686
             + +    PS    +     T NE          E       ENT     G   N E  A
Sbjct: 291  RTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTA 350

Query: 687  -----LTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLK 741
                 L P E  P E+      E+   S  +     + T ++ ++ + AE          
Sbjct: 351  NENTTLFPAE--PTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHG----- 403

Query: 742  VIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVY 801
                  PF +  T  +SA S+ +GE  P +   + T SP +  E  +  ++E T      
Sbjct: 404  ---ERTPFANDKTTSSSAESTEHGERTP-LANENTTPSPAEPTENRERTANENTTP---- 455

Query: 802  AEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFG 861
            +  G + + E +    K+  S V  T+N +  A +   TP  ++     Q  P     F 
Sbjct: 456  SPAGPTENRE-TTANEKTTLSPVEPTENRETTA-NEKTTPSPAEPTENGQRTP-----FA 508

Query: 862  NSNNILIATCVTDPTALG--TSVSQSNVVVLPG------------NSAPMTAQPLPPQLQ 907
            N       +   +PT  G  T ++  N    P              + P  A+P     +
Sbjct: 509  NEKT---TSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDR 565

Query: 908  TPPRSNSVF------AVNQAVSPNFSQGSAIIIASPVQ-----PVLQGMVGMIPVSVVGQ 956
            TP  +            N   +P  ++ +    A P +     P+        P      
Sbjct: 566  TPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTEN 625

Query: 957  -----NGNNFSTPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNK-------PCIG 1004
                 N N   +P     +  +TA   N     FP  P   + +    K       P   
Sbjct: 626  RERTANENTTPSPAGPTENREMTA---NEKTTLFPAEPTENRERTANEKTTSSPAEPTEN 682

Query: 1005 KQ----VNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSE-------ETTVPFPEESIV 1053
             Q     N    SS      H ++T +++++      + +E       E T PFP E   
Sbjct: 683  GQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTE 742

Query: 1054 PAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVS-STLKPPSN 1112
               +  +      ++T +P   T+  +   ++  K   +++ P  +      +  K  S+
Sbjct: 743  NRERTANE-----NTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSS 797

Query: 1113 NAIKRE-KEKPPLPK---ILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKE 1168
            +A   E  E+ PL       S +E   +R  T  E  ++    PTE    + ++ T    
Sbjct: 798  SAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFP 857

Query: 1169 NELCSDVERQKNPENSKLSIG-----QQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSV 1223
             E   + E   N EN+ LS       ++   L +EK+  S  E T + G  +   N  + 
Sbjct: 858  AEPTENREWTAN-ENTTLSPAEPTEHEEMTPLANEKTTLSPAEPT-ENGERTPFTNEKTT 915

Query: 1224 GTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEP 1283
             ++ +  +  +    ++ ITT    +   H    R+A+    P P  P      +H E  
Sbjct: 916  PSSAEPTEHGERTPLANEITTPSRAEPTEHG--ERIANEKATPSPAKP-----TEHGETT 968

Query: 1284 IDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASET 1322
            ++    PSS   +E+   +     P+  +    SP   T
Sbjct: 969  VNEDTTPSSAEPTENGERT-----PLANENTTTSPTEST 1002


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
            sapiens]
          Length = 699

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 77/383 (20%), Positives = 126/383 (32%), Gaps = 31/383 (8%)

Query: 1029 DKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNK 1088
            D S   +  +K      P P  S+ P + P  ++ L           TQ P   +  Q  
Sbjct: 269  DSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL----------GTQPPKKAVEKQQP 318

Query: 1089 ERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEK 1148
              ++    +    +     KPP+   + +   KPP  K  ++S S  S   +  + ++  
Sbjct: 319  VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS 378

Query: 1149 KVSPTEIVLESFHKATANKENELCSDVERQKNP--ENSKLSIGQQNGGLRSEKSIASLQE 1206
            K  P      S +K     ++         K P     KL   + +     E+S +S +E
Sbjct: 379  K--PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEE 436

Query: 1207 MTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLITTEMLQDIQRHSSVSRLADSSDLP 1266
             TKK   ++  K   +   A   L  +Q    S     +   D    SS      +S   
Sbjct: 437  KTKKMVATTKPK---ATAKAALSLPAKQAPQGS----RDSSSDSDSSSSEEEEEKTSKSA 489

Query: 1267 VPRTPGSGAGEKHKEEPIDII--KAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGS 1324
            V + P   AG     +P      KA SS   S D S+ +          P        G+
Sbjct: 490  VKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT 549

Query: 1325 ENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERERNSRP 1384
                      L   +  A   +      K       + S S  K+++ E   E E     
Sbjct: 550  S--------ALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAK 601

Query: 1385 SSKNLTNSSIPMKKKKIKKKKLP 1407
              K  T ++ P +KK  K+   P
Sbjct: 602  KIKLQTPNTFPKRKKGEKRASSP 624


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 89/458 (19%), Positives = 173/458 (37%), Gaps = 44/458 (9%)

Query: 474  QMSTETEMAI-GIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQ 532
            +M  E E A  G E+++ SS VP+ S    D  + P T       E   E   +S +  Q
Sbjct: 1228 EMQAEAEEAEEGEEEDAASSEVPAASPA--DSSNSPETETKEPEVEEEEEKPRVSEEQRQ 1285

Query: 533  LLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQL 592
               +   L  +P       E   D            + D  + H    +   LE   ++ 
Sbjct: 1286 SEEEQQELE-EPEP-----EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR- 1338

Query: 593  SNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQ 652
             + ++   +Q   L  +++ S   +  + E  L    S  +QPS+D++ V      +E  
Sbjct: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELD---SEEEQPSHDTSVVSEQMAGSEDD 1395

Query: 653  ASKSENSQEPSSSVKEENTIFLSLGGNANCEKV-ALTPPEGTPVENSHSLPPESVCSSVG 711
              +  +++E    +KEE  I  S       + V +LT  E +  E ++    E++ +   
Sbjct: 1396 HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC-- 1453

Query: 712  DSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTI 771
             +       D+ P  +   +  AS          + P  S  +  + +V S++  N+P +
Sbjct: 1454 QTLQSYTQADEDPQMSMVEDCHASE--------HNSPISSVQSHPSQSVRSVSSPNVPAL 1505

Query: 772  ------------ILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKS 819
                         LS+P+    + + ++   S  +    VV +   D  S+E +   +++
Sbjct: 1506 ESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYEN 1565

Query: 820  EDSAVNNTQNEDGIAFSANVTPC----VSKDGGYIQ---LMPATSTAFGNSNNILIATCV 872
              S+ ++T        S++ + C    +S      Q   ++     + G+S +++  + V
Sbjct: 1566 -PSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSV 1624

Query: 873  TDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPP 910
                       QS VV  P ++      P PPQ   PP
Sbjct: 1625 QPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP 1662


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 89/458 (19%), Positives = 173/458 (37%), Gaps = 44/458 (9%)

Query: 474  QMSTETEMAI-GIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQ 532
            +M  E E A  G E+++ SS VP+ S    D  + P T       E   E   +S +  Q
Sbjct: 1228 EMQAEAEEAEEGEEEDAASSEVPAASPA--DSSNSPETETKEPEVEEEEEKPRVSEEQRQ 1285

Query: 533  LLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQL 592
               +   L  +P       E   D            + D  + H    +   LE   ++ 
Sbjct: 1286 SEEEQQELE-EPEP-----EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR- 1338

Query: 593  SNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQ 652
             + ++   +Q   L  +++ S   +  + E  L    S  +QPS+D++ V      +E  
Sbjct: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELD---SEEEQPSHDTSVVSEQMAGSEDD 1395

Query: 653  ASKSENSQEPSSSVKEENTIFLSLGGNANCEKV-ALTPPEGTPVENSHSLPPESVCSSVG 711
              +  +++E    +KEE  I  S       + V +LT  E +  E ++    E++ +   
Sbjct: 1396 HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC-- 1453

Query: 712  DSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTI 771
             +       D+ P  +   +  AS          + P  S  +  + +V S++  N+P +
Sbjct: 1454 QTLQSYTQADEDPQMSMVEDCHASE--------HNSPISSVQSHPSQSVRSVSSPNVPAL 1505

Query: 772  ------------ILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKS 819
                         LS+P+    + + ++   S  +    VV +   D  S+E +   +++
Sbjct: 1506 ESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYEN 1565

Query: 820  EDSAVNNTQNEDGIAFSANVTPC----VSKDGGYIQ---LMPATSTAFGNSNNILIATCV 872
              S+ ++T        S++ + C    +S      Q   ++     + G+S +++  + V
Sbjct: 1566 -PSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSV 1624

Query: 873  TDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPP 910
                       QS VV  P ++      P PPQ   PP
Sbjct: 1625 QPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP 1662


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 89/458 (19%), Positives = 173/458 (37%), Gaps = 44/458 (9%)

Query: 474  QMSTETEMAI-GIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQ 532
            +M  E E A  G E+++ SS VP+ S    D  + P T       E   E   +S +  Q
Sbjct: 1228 EMQAEAEEAEEGEEEDAASSEVPAASPA--DSSNSPETETKEPEVEEEEEKPRVSEEQRQ 1285

Query: 533  LLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQL 592
               +   L  +P       E   D            + D  + H    +   LE   ++ 
Sbjct: 1286 SEEEQQELE-EPEP-----EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR- 1338

Query: 593  SNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVELNHTENEAQ 652
             + ++   +Q   L  +++ S   +  + E  L    S  +QPS+D++ V      +E  
Sbjct: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELD---SEEEQPSHDTSVVSEQMAGSEDD 1395

Query: 653  ASKSENSQEPSSSVKEENTIFLSLGGNANCEKV-ALTPPEGTPVENSHSLPPESVCSSVG 711
              +  +++E    +KEE  I  S       + V +LT  E +  E ++    E++ +   
Sbjct: 1396 HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC-- 1453

Query: 712  DSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTI 771
             +       D+ P  +   +  AS          + P  S  +  + +V S++  N+P +
Sbjct: 1454 QTLQSYTQADEDPQMSMVEDCHASE--------HNSPISSVQSHPSQSVRSVSSPNVPAL 1505

Query: 772  ------------ILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKS 819
                         LS+P+    + + ++   S  +    VV +   D  S+E +   +++
Sbjct: 1506 ESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYEN 1565

Query: 820  EDSAVNNTQNEDGIAFSANVTPC----VSKDGGYIQ---LMPATSTAFGNSNNILIATCV 872
              S+ ++T        S++ + C    +S      Q   ++     + G+S +++  + V
Sbjct: 1566 -PSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSV 1624

Query: 873  TDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPP 910
                       QS VV  P ++      P PPQ   PP
Sbjct: 1625 QPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP 1662


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 47/247 (19%), Positives = 104/247 (42%), Gaps = 20/247 (8%)

Query: 1127 ILSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKL 1186
            +   S  A+ + +T  E  S K     + + ++  + T  +++E+C+ +      ++ K 
Sbjct: 747  LTDSSTDALEKVSTSNEDFSLKD----DALAKTSKRKTKVQKDEICAKLSHVIKKQHRKS 802

Query: 1187 SIGQQNGGLRSEKSIASLQEMTKKQGTSSNN-----KNVLSVGTAVKDLKQEQTKSASSL 1241
            ++      L    ++++++    ++ T          N+    + V D K  + KS +++
Sbjct: 803  TLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPSGVLDDKNGEQKSQNNV 862

Query: 1242 ITTEM------LQDIQRHSSVSRL----ADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPS 1291
            +  E       L     H +  ++     D  +L +P T  + A EK      D++  P 
Sbjct: 863  LPKEKQLKNEELVIFSFHENNCKIQEFHVDGKEL-IPFTEMTNASEKKSSPFKDLMTVPE 921

Query: 1292 SRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSRAAISRTTSATP 1351
            SR     +STS +         P  SP S+T +++ ++   H L +L++A++    S +P
Sbjct: 922  SRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRDLHKLSLLAQASVITFPSDSP 981

Query: 1352 LKDNTQQ 1358
               +  Q
Sbjct: 982  QNSSQLQ 988


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 76/309 (24%), Positives = 115/309 (37%), Gaps = 64/309 (20%)

Query: 628 SLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVAL 687
           S+++T+  S+ + S   + T  E   + S ++   SSS+    T        +   + A+
Sbjct: 306 SITTTETNSHSTTSFTSSITTTE---TTSHSTPSFSSSITTTETXXXXXXXTS---ETAV 359

Query: 688 TPPEGTPVENSHSLPPESVC----SSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVI 743
           TP   TP   S  +P  S+     SSVG S   +  TD       S   D S + +   I
Sbjct: 360 TPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFP-----SIPTDISTLPTRTHI 414

Query: 744 ISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAE 803
           IS  P + S     +  SS+ G   PT+     T   T+N  +     S  +   VV  E
Sbjct: 415 ISSSPSIQS-----TETSSLVGTTSPTMSTVRMTLRITENTPI-----SSFSTSIVVIPE 464

Query: 804 VGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNS 863
                                           +   TP V       Q  PA +T    S
Sbjct: 465 --------------------------------TPTQTPPVLTSATGTQTSPAPTTVTFGS 492

Query: 864 NNILIATC--VTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQA 921
            +   +T   +T  TAL T VS S V +   +S+ +   P  P LQT   S S F     
Sbjct: 493 TDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEF----- 547

Query: 922 VSPNFSQGS 930
            + +F++GS
Sbjct: 548 TTESFTRGS 556


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 107/580 (18%), Positives = 213/580 (36%), Gaps = 57/580 (9%)

Query: 159 RPSGQISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRK 218
           R S Q SDP           +  D        +V+  ++E+     +      +   QR 
Sbjct: 94  RESRQESDP-----------EDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRN 142

Query: 219 STTLSGPHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNNIA 278
                    T++ F+  +  A E+Q   +   +K+      + K  EN  + L  +    
Sbjct: 143 RRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAK 202

Query: 279 QVP----------KQTDNNPTEPETSIDEFLGLPSEIHMSE------EAIQDILEQTESD 322
           Q             Q      E    I +++   ++ H+         A Q ++E  ES 
Sbjct: 203 QTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIE--ESQ 260

Query: 323 PAFQALFDLFDYGKTKNNKNISQSISSQPMESNPSIVLADETNLAVKGSFETEESDGQSG 382
               ALF+          + I  +     ME+ P      E    V  + E ++++ + G
Sbjct: 261 RKMNALFE---------GRRIEFAEQINKMEARPRRQSMKEKEHQVVRN-EEQKAEQEEG 310

Query: 383 QPAFCTSYQNDDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDI 442
           + A     Q ++ L    N +N   + +  +E   +I+  +   A K     EQK ++++
Sbjct: 311 KVA-----QREEELEETGNQHNDVEIEEAGEEEEKEIAI-VHSDAEKEQEEEEQKQEMEV 364

Query: 443 TFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQP 502
             E    + +  ++ +S  E      E+  N      +  + +E N + S  PSE++   
Sbjct: 365 KMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEV-METNRVESVEPSENEASK 423

Query: 503 D-QPDI-----PITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSND 556
           + +P++     P     SL     N + +   K S+   +  S   +P   +Q    S  
Sbjct: 424 ELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKES-EPQPEPVAQPQPQSQP 482

Query: 557 TVKLKINFHGSKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPV-SVESSHL 615
            ++L+        S         + + VL+P   Q++  Q +   + +  PV SV+ + +
Sbjct: 483 QLQLQSQSQPVLQSQPPS-QPEDLSLAVLQPT-PQVTQEQGHLLPERKDFPVESVKLTEV 540

Query: 616 NVSGQVEIH-LGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFL 674
            V   + +H    S + T+  S   A  + + + + + +S S +S   SSS    ++   
Sbjct: 541 PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600

Query: 675 SLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSH 714
           S   +++    + +        +S S   ES   S G  H
Sbjct: 601 SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGH 640


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 80/370 (21%), Positives = 137/370 (37%), Gaps = 51/370 (13%)

Query: 584  VLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPSNDSASVE 643
            V+E     L+  QD+ C  S+     V      V  Q E+ +      +K+    S   +
Sbjct: 1411 VVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQ-EVKMVVPEDQSKKDGQPSDPNK 1469

Query: 644  LNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGT------PVEN 697
            L   E        EN    S +++E  T    L  N+    V + PP  T      PV +
Sbjct: 1470 LPSVE--------ENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVS 1521

Query: 698  SHSLPPESVCSSVGD--SHPESQNTDDKPSSN---NSAEIDASNIVSLKVIISDDPFVSS 752
               L   SV  ++ D  S  E  N+ + P SN   +S      + VS  V  S  P +S 
Sbjct: 1522 GEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSR 1581

Query: 753  DTELTSAVSSINGENLPTIILSSP-TKSPTKNAELVKCLSSEETVGAVVYAEVGDSASME 811
                +S  + +    +   + S+P T S   +A L   L S      V     G      
Sbjct: 1582 PVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAG------ 1635

Query: 812  QSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATC 871
              ++  + + +A +N + +        +TP        IQ+M  +       + I  A  
Sbjct: 1636 SKVMVSEGQSAAQSNARPQ-------FITPVFINSSSIIQVMKGS-----QPSTIPAAPL 1683

Query: 872  VTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSA 931
             T+   +  SV+    + +P N    ++ P+PP            A++ + +PN   G  
Sbjct: 1684 TTNSGLMPPSVAVVGPLHIPQN-IKFSSAPVPPN-----------ALSSSPAPNIQTGRP 1731

Query: 932  IIIASPVQPV 941
            ++++S   PV
Sbjct: 1732 LVLSSRATPV 1741



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 62/302 (20%), Positives = 119/302 (39%), Gaps = 44/302 (14%)

Query: 1083 MVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIK----REKEKPPLPKILSKSESAISRH 1138
            +V+  K+ N+ +     SP+ S    P S+        R+  K P   + S++ +A+ ++
Sbjct: 1309 VVNSGKQSNSGATKRA-SPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQN 1367

Query: 1139 TTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSE 1198
                E      VSPT +       +  N             NP+NS +S+    G +   
Sbjct: 1368 V---ELPRNVLVSPTPLANPPVPGSFPNNSG---------LNPQNSTVSVAAVGGVVEDN 1415

Query: 1199 KSIASLQEMTKKQGTSSNNK--NVLSVGTAVKDLK----QEQTKSASSLITTEMLQDIQR 1252
            K   ++ + +  Q + S  +  N+       +++K    ++Q+K          L  ++ 
Sbjct: 1416 KESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEE 1475

Query: 1253 H------------SSVSRLADSSDLPVPRTPGSGAGEKHKEEPI----DIIKA---PSSR 1293
            +            +S+S+L D+S  P       G  +     P+    D+ KA   P+ +
Sbjct: 1476 NKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535

Query: 1294 RFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSRAAISRTTSATPLK 1353
              S     S  +  P + +L +     E  SE S N+A     ++SR  +S ++ +TPL 
Sbjct: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPEL-SEVSSNVAPSIPPVMSR-PVSSSSISTPLP 1593

Query: 1354 DN 1355
             N
Sbjct: 1594 PN 1595


>gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens]
          Length = 259

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/220 (18%), Positives = 81/220 (36%), Gaps = 24/220 (10%)

Query: 990  KSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKT-EVSDKSIATD-LGKKSEETTVPF 1047
            K QKA+GL  K C  K   + +++ G+    +++ T  + D+ + ++ +        +P 
Sbjct: 20   KVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQRLPSETIQTYPRSCNIPQ 79

Query: 1048 PEESIVPAAKPCHRRVL-------------CFDSTTAP--------VANTQGPNHKMVSQ 1086
              E+ +P   P H   L             CF     P        +  + G  H++   
Sbjct: 80   TVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQQEYICGSHGVEHRVYKH 139

Query: 1087 NKERNAVSFPNLDSPNVSSTLK-PPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQ 1145
                N+ S        +    K  P     K E+E+    +  S  E  + +H +I+  +
Sbjct: 140  FSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKK 199

Query: 1146 SEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSK 1185
            +E ++    +  E        K  ++ S  E +K  +  K
Sbjct: 200  TEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKK 239


>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
           [Homo sapiens]
          Length = 1063

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 78/342 (22%), Positives = 139/342 (40%), Gaps = 56/342 (16%)

Query: 628 SLSSTKQPSNDS----ASVELNHTENEAQAS------KSENSQEPSSSVKEENTIFLSLG 677
           S++ST+  S+ +    +S+  N T + +  S      K++ +   + S    N+I  S  
Sbjct: 83  SITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITKTKTTSHSTPSFTSSNSITDSRS 142

Query: 678 GNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNI 737
            +      ++T PE T    SH+ P  S  SS+  +   S +T    SS   + + +S  
Sbjct: 143 HSTPPFTSSVTTPEMT----SHNTP--SFMSSIITTETTSHSTPSFTSSTIHSTVSSSTT 196

Query: 738 VSLKVIISDDPFVSSDTELTSAVSSING--ENLPTIILS-------SPTKSPTKNAELVK 788
                     PF +++T +TS  SS +    ++PT  L        S + S T   +L  
Sbjct: 197 AITS------PFTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPS 250

Query: 789 C---LSSEETVGAVVYAEVGDSASMEQSLL-----TFKSEDSAVNNTQNEDGIAFSAN-- 838
               +SS  T   ++ +     ++   SL+     T  +  + + +T+N    +FS +  
Sbjct: 251 IPTDISSLPTPIHIISSSPSIQSTETSSLVGTTSPTMSTVRATLRSTENTPISSFSTSIV 310

Query: 839 VTP----------CVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVV 888
           VTP           +S  G     +P T T     ++      +T  TAL   +S S   
Sbjct: 311 VTPETPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMSTSQFP 370

Query: 889 VLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGS 930
           +   +S+ +   P  P LQT   S S F      + +F++GS
Sbjct: 371 IPSTHSSTLQTTPSIPSLQTSLTSTSEF-----TTESFTRGS 407


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 41.6 bits (96), Expect = 0.006
 Identities = 81/402 (20%), Positives = 149/402 (37%), Gaps = 87/402 (21%)

Query: 1038 KKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERNAVSFPN 1097
            K++  +T PFPEE  +  +K    +V+      A       P  K+ +Q K  +++    
Sbjct: 2087 KEAHRSTPPFPEEKPLEESKMVQSKVI----DDADEGKKPSPEVKIPTQRKPISSIHARE 2142

Query: 1098 LDSP-NVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQSEKKVSPTEIV 1156
              SP +   T  PP+   +     KP LP                 E + +K +S  +  
Sbjct: 2143 PQSPESPEVTQNPPTQPKV----AKPDLP-----------------EEKGKKGISSFKSW 2181

Query: 1157 LESFHKATANKENELC--SDVERQKNPENSK-LSIGQQNGGLRSEKSIA------SLQEM 1207
            + S    ++  +N++    D+E Q +P   K +++    G + +  ++A      SL E+
Sbjct: 2182 MSSLFFGSSTPDNKVAEQEDLETQPSPSVEKAVTVIDPEGTIPTNFNVAEKPADHSLSEV 2241

Query: 1208 TKKQGTSSNNKNVLSVGTAVKDLKQEQTKSASSLIT-TEMLQDIQRHSSVSR-------- 1258
              K             GT VK    +  K  S +++  E LQ  +  S VSR        
Sbjct: 2242 KLKTADEPR-------GTLVKSGDGQNVKEKSMILSNVEDLQQPKFISEVSREDYGKKEI 2294

Query: 1259 LADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSP 1318
              DS ++ +     S  GE  + +   +I     +   E+   +K +VPP   D      
Sbjct: 2295 SGDSEEMNINSVVTSADGENLEIQSYSLI---GEKLVMEE---AKTIVPPHVTD------ 2342

Query: 1319 ASETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQFRASSRSTTKKRKI---EEL 1375
                                    + +   A P K N   F+   RS  K++ +   + +
Sbjct: 2343 ---------------------SKRVQKPAIAPPSKWNISIFKEEPRSDQKQKSLLSFDVV 2381

Query: 1376 DERERNSRPSSKNLTNSSIPMKKKKIKKKKLPSSFPAGMDVD 1417
            D+  +  + +S N  + +I  + +K +   LP     G  +D
Sbjct: 2382 DKVPQQPKSASSNFASKNITKESEKPESIILPVEESKGSLID 2423



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 67/301 (22%), Positives = 118/301 (39%), Gaps = 56/301 (18%)

Query: 468  AELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIPITSFVSLGCEANNENLILS 527
            ++L   Q  TE  +      +  +  +P  S    D+ D+ I  F  +      ENL L 
Sbjct: 1815 SDLLVEQKKTEKAL-----HSDQTVKLPDVSTSSEDKQDLGIKQFSLM-----RENLPLE 1864

Query: 528  GKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKI------- 580
               S + ++   +  K +K  +F  +  D      N+   K  + +  H+ +I       
Sbjct: 1865 QSKSFMTTKPADV--KETKMEEFFISPKDE-----NWMLGKPENVASQHEQRIAGSVQLD 1917

Query: 581  --EINVLEPVMSQLS-NCQDNSC-LQSEILPVSVESSHLNVSGQVEIHLGDSLSSTKQPS 636
                N L P   + + + +D++C ++ ++LP S E SHL+ S +    L  S  +T+  S
Sbjct: 1918 SSSSNELRPGQLKAAVSSKDHTCEVRKQVLPHSAEESHLS-SQEAVSALDTSSGNTETLS 1976

Query: 637  NDSASVEL--------------NHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANC 682
            + S S E               N   N A+  +  +  E  S + E+    LS     + 
Sbjct: 1977 SKSYSSEEVKLAEEPKSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKEDS 2036

Query: 683  EKVALTPPE--------GTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDA 734
            ++    PPE        G  VE   S   E++ SSV  +H  ++  +  P+  N  E   
Sbjct: 2037 QEKIKLPPERFFQKPVSGLSVEQVKS---ETISSSVKTAHFPAEGVE--PALGNEKEAHR 2091

Query: 735  S 735
            S
Sbjct: 2092 S 2092



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 217/1121 (19%), Positives = 390/1121 (34%), Gaps = 185/1121 (16%)

Query: 362  DETNLAVKGSFETEESDGQSGQPAFCTSYQNDDPLNALKNSNNHDV---LRQEDQENFSQ 418
            +E  LA  G+  +E     S  P+F    + +D  +A  + +       L    Q+    
Sbjct: 396  EECELASPGTAASENDSSVS--PSFANEVKKEDVYSAHHSISLEAASPGLAASTQDGLDP 453

Query: 419  ISTSIQKKAFKTAVPTEQKCDIDITFESVPNLNDFNQRGNSNAECNPHCAELYTNQMSTE 478
                    + + A P   K  +  T  SV    + N    S +   P   E    +   E
Sbjct: 454  DQEQPDLTSIERAEPVSAK--LTPTHPSVKGEKEENMLEPSISLSEPLMLE-EPEKEEIE 510

Query: 479  TEMAIGIEKNSLSSNVPSESQLQPDQPDIPITS------FVSLGCEANNENLIL------ 526
            T + I I      SN+  E  ++ D P+ P+ S       +S   E   E LIL      
Sbjct: 511  TSLPIAITPEPEDSNLVEEEIVELDYPESPLVSEKPFPPHMSPEVEHKEEELILPLLAAS 570

Query: 527  SGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHGSKSSDSSEVHKSKIEINVLE 586
            S +   L  ++       S  S F   S  +V   +N H  +  +   V  S +E     
Sbjct: 571  SPEHVALSEEEREEIASVSTGSAFV--SEYSVPQDLN-HELQEQEGEPVPPSNVEAIAEH 627

Query: 587  PVMSQLSNCQDNS-------CLQSEILPVSVESSHLN-------VSGQVEIHLGDSLSST 632
             V+S+  N +  +         +S + P + E +  N       V+ +  +  GD  S +
Sbjct: 628  AVLSEEENEEFEAYSPAAAPTSESSLSPSTTEKTSENQSPLFSTVTPEYMVLSGDEASES 687

Query: 633  KQPSNDSASV---ELNHTENEAQASKSENSQEP-----------SSSVKEENTIFLSLGG 678
               + DS S     +     +    K+ + + P            S  KE+   F     
Sbjct: 688  GCYTPDSTSASEYSVPSLATKESLKKTIDRKSPLILKGVSEYMIPSEEKEDTGSFTPAVA 747

Query: 679  NANCEKVALTPPEGTPVENSHSLP----PESVCSSVG-DSHPESQNTDDKPSSNNSAEID 733
             A+   ++ +  E T  E    LP     E V  S G D   E    D K  S  +A ++
Sbjct: 748  PASEPSLSPSTTEKTS-ECQSPLPSTATSEHVVPSEGEDLGSERFTPDSKLISKYAAPLN 806

Query: 734  ASNIVSLKVIISDDPF----VSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVK- 788
            A+     K+I     F    +S  T L+     + G + P ++++S    P    E+   
Sbjct: 807  ATQESQKKIINEASQFKPKGISEHTVLSVDGKEVIGPSSPDLVVASEHSFPPHTTEMTSE 866

Query: 789  --------------CLSSEETVGAVVYAEVGDSASMEQSLLTFKS----EDSAVNNTQNE 830
                           LS EE V    Y     SAS E S+  + +    E+  V+ + N 
Sbjct: 867  CQAPPLSATPSEYVVLSDEEAVELERYTPSSTSAS-EFSVPPYATPEAQEEEIVHRSLNL 925

Query: 831  DGIAFSANVTP-------CVSKDGGYIQLMP----ATSTAFGNSNNILIATCVTDP---T 876
             G +   N++          S D  ++        AT  A           C+T P   T
Sbjct: 926  KGASSPMNLSEEDQEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTSPSEHT 985

Query: 877  ALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIAS 936
             L    ++   +  P +++ ++   +PP   +    N +   +  ++   + G +    +
Sbjct: 986  ILSDEDTEEAELFSPDSASQVS---IPPFRISETEKNEL-EPDSLLTAVSASGYSCFSEA 1041

Query: 937  PVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLH-MPLTAPVCNRSIPQFPVPPKSQKAQ 995
              + +  G     PVS        FS+  +Q     PL +P+ + S+P  P   KS+KA+
Sbjct: 1042 DEEDI--GSTAATPVS------EQFSSSQKQKAETFPLMSPLEDLSLP--PSTDKSEKAE 1091

Query: 996  GLRNKPCIGKQVNN-------------LVDSSGHSVGCH--------AQKTEVSDKSIAT 1034
                 P     V+              L   S   +  H         ++   S  +I  
Sbjct: 1092 IKPEIPTTSTSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEVEKGEREASSSVAAIPA 1151

Query: 1035 DLGKKS---EETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNKERN 1091
             L  +S   +E T P    S++P + P  ++       TA +          +S+ ++  
Sbjct: 1152 ALPAQSSIVKEETKPASPHSVLPDSVPAIKKE---QEPTAALTLKAADEQMALSKVRKEE 1208

Query: 1092 AVSFPNLDSPNVS--STLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQ--SE 1147
             V      + +VS    ++P   N  + E +   LP ++ + +  +     +  T    +
Sbjct: 1209 IVPDSQEATAHVSQDQKMEPQPPNVPESEMKYSVLPDMVDEPKKGVKPKLVLNVTSELEQ 1268

Query: 1148 KKVS---PTEIVLESFHKATANKENELCSDVERQKNPEN----SKLSIGQQNGGLRSE-- 1198
            +K+S   P  I   S  K T+    E  S V+ +   ++    + + +   + G+  +  
Sbjct: 1269 RKLSKNEPEVIKPYSPLKETSLSGPEALSAVKMEMKHDSKITTTPIVLHSASSGVEKQVE 1328

Query: 1199 -----KSIASLQEMTKKQ---GTSSNNKNVLSVGTAVKDLKQEQTKSASSLIT------- 1243
                  + ++L E  KK+    +S+   +V  + + +    +E+  + SSLIT       
Sbjct: 1329 HGPPALAFSALSEEIKKEIEPSSSTTTASVTKLDSNLTRAVKEEIPTDSSLITPVDRPVL 1388

Query: 1244 ------------TEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKH-----KEEPIDI 1286
                          ++     HS    LA+   + +          KH      E+ I  
Sbjct: 1389 TKVGKGELGSGLPPLVTSADEHSV---LAEEDKVAIKGASPIETSSKHLAWSEAEKEIKF 1445

Query: 1287 IKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENS 1327
               PS    +E S  S+V    V   LP    +S   S+ S
Sbjct: 1446 DSLPSVSSIAEHSVLSEVEAKEVKAGLPVIKTSSSQHSDKS 1486


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
            sapiens]
          Length = 1450

 Score = 41.2 bits (95), Expect = 0.007
 Identities = 169/963 (17%), Positives = 329/963 (34%), Gaps = 118/963 (12%)

Query: 496  SESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSN 555
            S S+   D  D  + + V+   E +  N++ +  +S      +   G P K         
Sbjct: 547  SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS------SPAKGPPQKAGPVAVQVK 600

Query: 556  DTVKLKINFHGSKSSDSSEVHKSKIEINVLE--PVMS--QLSNC--QDNSCLQSEILPVS 609
                +  +    +SSDS++  ++   +   +  P +   Q   C  + N+   +++ PV 
Sbjct: 601  AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660

Query: 610  VESSHLNVSGQVEIHLGDS---LSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSV 666
            V +     +G      G S      T++P+ DS+S E + +E E         Q  S   
Sbjct: 661  VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSV-- 718

Query: 667  KEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSS 726
                       G     K A  P +G+  + +  + P     +V     E Q   +    
Sbjct: 719  -----------GKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE 767

Query: 727  NNSAEIDASNIVSLKVIISDDPFVSSDT--ELTSAVSSINGEN-LPTIILSSPTKSPTKN 783
             + +E  A++   +K  +      ++       SA  +I+    + T    +  +SP+K 
Sbjct: 768  ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 827

Query: 784  AELVKCLSSEETV--GAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTP 841
               V+   +   +  G      VG + +      T   EDS   +++ E      A    
Sbjct: 828  KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--SSEEESDSEEEAETLA 885

Query: 842  CVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQP 901
             V   G   Q+  A + A  +          T P   G S +Q+      G+S+      
Sbjct: 886  QVKPSGKTHQIRAALAPAKESPRK---GAAPTPPGKTGPSAAQAGKQDDSGSSSE----- 937

Query: 902  LPPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNF 961
                      S+S      AV+      SA +I  P+  V        P +   Q     
Sbjct: 938  ---------ESDSDGEAPAAVT------SAQVIKPPLIFVDPNRSPAGPAATPAQ-AQAA 981

Query: 962  STPPRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCH 1021
            STP +            + S  +  +P       G+R         +  +       G  
Sbjct: 982  STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 1041

Query: 1022 AQK--TEVSD----KSIATDLGKKSEETTVPFPEESIVPAA------KPCHRRVLCFDST 1069
            + K  + +SD    +  AT +           P+ + V A       KP    V    +T
Sbjct: 1042 SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ--QAT 1099

Query: 1070 TAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILS 1129
             AP ++    +    S   E +        S +        +   ++    +     +++
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVA 1159

Query: 1130 KSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIG 1189
             S+S +S + T   T +  + S     L+S    ++    +   D +++  P+ +   + 
Sbjct: 1160 PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1219

Query: 1190 QQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKD--------LKQEQTKSASSL 1241
             + GG  +       +    K+G  +   + L++ + +          L + Q +++   
Sbjct: 1220 PKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVK 1279

Query: 1242 ITTEMLQDIQRHSSVSRLADSS-------------DLPVPRTPGS------GAGEKHKEE 1282
            + TE+L+  +R   V    +SS             D P  RTP S      GAGE  +  
Sbjct: 1280 VLTELLEQ-ERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE-- 1336

Query: 1283 PIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSRAA 1342
                  A  S   +  +S  K      + D+         GS+ + +     L       
Sbjct: 1337 ------ASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGT 1389

Query: 1343 ISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERERNSRPSSKNLTNSSIPMKKKKIK 1402
            +     + P      + +   + + K++K +E  E+++ ++ +S    +S  P +KKK K
Sbjct: 1390 VEGGDQSNP------KSKKEKKKSDKRKKDKEKKEKKKKAKKASTK--DSESPSQKKKKK 1441

Query: 1403 KKK 1405
            KKK
Sbjct: 1442 KKK 1444



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 57/262 (21%), Positives = 101/262 (38%), Gaps = 42/262 (16%)

Query: 639 SASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENS 698
           +A V++   E ++++S SE S     ++   N   +   G +   K A T   G   + +
Sbjct: 463 AAQVQVGKQEEDSRSS-SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521

Query: 699 HSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS 758
             +PP      VG + P +Q    +  S +S+E  +                SSD E+ +
Sbjct: 522 GPVPP----GKVGPATPSAQVGKWEEDSESSSEESSD---------------SSDGEVPT 562

Query: 759 AVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFK 818
           AV+    ++L  I+ + PT SP K           +  G V   +V     M+ S  + +
Sbjct: 563 AVAPAQEKSLGNILQAKPTSSPAK--------GPPQKAGPVA-VQVKAEKPMDNSESSEE 613

Query: 819 SEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTAL 878
           S DSA  +++       +A   P +         +P T      +N    A+    P  +
Sbjct: 614 SSDSA--DSEEAPAAMTAAQAKPALK--------IPQTKACPKKTNT--TASAKVAPVRV 661

Query: 879 GTSV-SQSNVVVLPGNSAPMTA 899
           GT    ++     P  S+P  A
Sbjct: 662 GTQAPRKAGTATSPAGSSPAVA 683


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 120/529 (22%), Positives = 186/529 (35%), Gaps = 107/529 (20%)

Query: 627  DSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLG--------- 677
            D  SS KQ  + S S     ++ E  +S SEN+  PSS+ K +N +  S           
Sbjct: 1186 DIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQK 1245

Query: 678  ------GNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSN--NS 729
                   + N E +     E TP+  S      S+ SS  D    +Q T +  S+N    
Sbjct: 1246 AATCKVSSINQETIQTYCVEDTPICFSRCSSLSSL-SSAEDEIGCNQTTQEADSANTLQI 1304

Query: 730  AEI-------DASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTK 782
            AEI        A + VS    +S  P   S     S++SS +  +   +  SS  KSP+K
Sbjct: 1305 AEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH-KAVEFSSGAKSPSK 1363

Query: 783  NAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPC 842
                    S  +T  +     V ++  M     +  S DS  + +     IA S    PC
Sbjct: 1364 --------SGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS-----IASSVQSEPC 1410

Query: 843  VSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPL 902
                 G I                                S S++   PG + P      
Sbjct: 1411 SGMVSGII--------------------------------SPSDLPDSPGQTMP------ 1432

Query: 903  PPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFS 962
            P + +TPP         + V  N +  +    + P Q  +   V  + V        +F+
Sbjct: 1433 PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFA 1492

Query: 963  TP--------PRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSS 1014
            T            +  + L  P   + +    +PP  +   G   +    K+ N   +  
Sbjct: 1493 TESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEK- 1551

Query: 1015 GHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTA--- 1071
                   A+KT  S+K +  D    S++  +   EE I+ A      R     + TA   
Sbjct: 1552 ------EAEKTIDSEKDLLDD----SDDDDIEILEECIISAMPTKSSRKAKKPAQTASKL 1601

Query: 1072 --PVAN--TQGPNHKMV-SQNK--ERNAVSF-PNLDSPNVSSTLKPPSN 1112
              PVA   +Q P +K++ SQN+   +  VSF P  D P V      P N
Sbjct: 1602 PPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPIN 1650


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 120/529 (22%), Positives = 186/529 (35%), Gaps = 107/529 (20%)

Query: 627  DSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLG--------- 677
            D  SS KQ  + S S     ++ E  +S SEN+  PSS+ K +N +  S           
Sbjct: 1186 DIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQK 1245

Query: 678  ------GNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSN--NS 729
                   + N E +     E TP+  S      S+ SS  D    +Q T +  S+N    
Sbjct: 1246 AATCKVSSINQETIQTYCVEDTPICFSRCSSLSSL-SSAEDEIGCNQTTQEADSANTLQI 1304

Query: 730  AEI-------DASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTK 782
            AEI        A + VS    +S  P   S     S++SS +  +   +  SS  KSP+K
Sbjct: 1305 AEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH-KAVEFSSGAKSPSK 1363

Query: 783  NAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPC 842
                    S  +T  +     V ++  M     +  S DS  + +     IA S    PC
Sbjct: 1364 --------SGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS-----IASSVQSEPC 1410

Query: 843  VSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPL 902
                 G I                                S S++   PG + P      
Sbjct: 1411 SGMVSGII--------------------------------SPSDLPDSPGQTMP------ 1432

Query: 903  PPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFS 962
            P + +TPP         + V  N +  +    + P Q  +   V  + V        +F+
Sbjct: 1433 PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFA 1492

Query: 963  TP--------PRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSS 1014
            T            +  + L  P   + +    +PP  +   G   +    K+ N   +  
Sbjct: 1493 TESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEK- 1551

Query: 1015 GHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTA--- 1071
                   A+KT  S+K +  D    S++  +   EE I+ A      R     + TA   
Sbjct: 1552 ------EAEKTIDSEKDLLDD----SDDDDIEILEECIISAMPTKSSRKAKKPAQTASKL 1601

Query: 1072 --PVAN--TQGPNHKMV-SQNK--ERNAVSF-PNLDSPNVSSTLKPPSN 1112
              PVA   +Q P +K++ SQN+   +  VSF P  D P V      P N
Sbjct: 1602 PPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPIN 1650


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 120/529 (22%), Positives = 186/529 (35%), Gaps = 107/529 (20%)

Query: 627  DSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLG--------- 677
            D  SS KQ  + S S     ++ E  +S SEN+  PSS+ K +N +  S           
Sbjct: 1186 DIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQK 1245

Query: 678  ------GNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSN--NS 729
                   + N E +     E TP+  S      S+ SS  D    +Q T +  S+N    
Sbjct: 1246 AATCKVSSINQETIQTYCVEDTPICFSRCSSLSSL-SSAEDEIGCNQTTQEADSANTLQI 1304

Query: 730  AEI-------DASNIVSLKVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTK 782
            AEI        A + VS    +S  P   S     S++SS +  +   +  SS  KSP+K
Sbjct: 1305 AEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH-KAVEFSSGAKSPSK 1363

Query: 783  NAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPC 842
                    S  +T  +     V ++  M     +  S DS  + +     IA S    PC
Sbjct: 1364 --------SGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS-----IASSVQSEPC 1410

Query: 843  VSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPL 902
                 G I                                S S++   PG + P      
Sbjct: 1411 SGMVSGII--------------------------------SPSDLPDSPGQTMP------ 1432

Query: 903  PPQLQTPPRSNSVFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFS 962
            P + +TPP         + V  N +  +    + P Q  +   V  + V        +F+
Sbjct: 1433 PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFA 1492

Query: 963  TP--------PRQVLHMPLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSS 1014
            T            +  + L  P   + +    +PP  +   G   +    K+ N   +  
Sbjct: 1493 TESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEK- 1551

Query: 1015 GHSVGCHAQKTEVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTA--- 1071
                   A+KT  S+K +  D    S++  +   EE I+ A      R     + TA   
Sbjct: 1552 ------EAEKTIDSEKDLLDD----SDDDDIEILEECIISAMPTKSSRKAKKPAQTASKL 1601

Query: 1072 --PVAN--TQGPNHKMV-SQNK--ERNAVSF-PNLDSPNVSSTLKPPSN 1112
              PVA   +Q P +K++ SQN+   +  VSF P  D P V      P N
Sbjct: 1602 PPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPIN 1650


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
            [Homo sapiens]
          Length = 1488

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 130/708 (18%), Positives = 252/708 (35%), Gaps = 145/708 (20%)

Query: 647  TENEAQASKSENS---QEPSSSVKEENTIF-LSLGGNANCEKVALTPPEGTPVENSHSLP 702
            T  +AQ    E+S   +E S S +E  T+  +   G  +  + AL P + +P + +   P
Sbjct: 856  TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915

Query: 703  PESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSS 762
            P       G S  ++   DD  SS+  ++                    SD E  +AV+S
Sbjct: 916  P----GKTGPSAAQAGKQDDSGSSSEESD--------------------SDGEAPAAVTS 951

Query: 763  INGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDS 822
                  P +I   P +SP                 A   A+   +++  ++  +  +  S
Sbjct: 952  AQVIK-PPLIFVDPNRSPAG--------------PAATPAQAQAASTPRKARASESTARS 996

Query: 823  AVNNTQNEDGIAFSANVTP-----CVSKDGGYIQLMPATSTAFGNSNNILIATCVTD--- 874
            + + +++ED I  +  +TP      V+    + ++ P  S A  +S+    ++ ++D   
Sbjct: 997  SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK--ESSRISDGKK 1054

Query: 875  PTALGTSVSQSNVVVLPGNSAPM------TAQPLPPQLQTPPRS--NSVFAVNQAVSPNF 926
                 T VS+ N   LP   A +       ++  PP  +T P S  +S      A SP  
Sbjct: 1055 QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQ- 1113

Query: 927  SQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFP 986
                                     SV  +  N    P    +     AP  +       
Sbjct: 1114 -----------------------STSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150

Query: 987  VPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVP 1046
                  +  G   +             S H++G    +TE    ++  +   +S E  V 
Sbjct: 1151 DSSSGSEEDGEGPQGA----------KSAHTLGPTPSRTE----TLVEETAAESSEDDVV 1196

Query: 1047 FPEESIV---------PAAKPCHRRVLCFDST---TAPVANTQGPNHKMVSQNKERNAVS 1094
             P +S++         PA     +     DS+   ++ +A    P+ K  ++ ++   + 
Sbjct: 1197 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1256

Query: 1095 FPNLDSPNVSSTLKPPSNNAIKREKEKP------------------PLPKILSKSESAIS 1136
             P       +S   P  +   K+    P                  P P   ++ ++++ 
Sbjct: 1257 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1316

Query: 1137 RHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPEN-SKLSIGQQNGGL 1195
            +  T    Q  KKV  T    ES  K   +++ +L  D    + P +  K  +G   GG 
Sbjct: 1317 KVLTELLEQERKKVVDT--TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG- 1373

Query: 1196 RSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSA--SSLITTEMLQDIQRH 1253
              E S++  +  T  +G +  +K       A  D+K+++ K +  S     E  +++Q+ 
Sbjct: 1374 --EASVSPEKTSTTSKGKAKRDK-------ASGDVKEKKGKGSLGSQGAKDEPEEELQKG 1424

Query: 1254 SSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSST 1301
                   D S+ P  +     + ++ K++     K  + +  ++DS +
Sbjct: 1425 MGTVEGGDQSN-PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1471



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 63/365 (17%), Positives = 135/365 (36%), Gaps = 45/365 (12%)

Query: 1068 STTAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKI 1127
            +T AP ++    +    S   E +        S +        +   ++    +     +
Sbjct: 1136 ATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDV 1195

Query: 1128 LSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLS 1187
            ++ S+S +S + T   T +  + S     L+S    ++    +   D +++  P+ +   
Sbjct: 1196 VAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGM 1255

Query: 1188 IGQQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKD--------LKQEQTKSAS 1239
            +  + GG  +       +    K+G  +   + L++ + +          L + Q +++ 
Sbjct: 1256 LSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1315

Query: 1240 SLITTEMLQDIQRHSSVSRLADSS-------------DLPVPRTPGS------GAGEKHK 1280
              + TE+L+  +R   V    +SS             D P  RTP S      GAGE  +
Sbjct: 1316 VKVLTELLEQ-ERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1374

Query: 1281 EEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSR 1340
                    A  S   +  +S  K      + D+         GS+ + +     L     
Sbjct: 1375 --------ASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ-KGM 1425

Query: 1341 AAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERERNSRPSSKNLTNSSIPMKKKK 1400
              +     + P      + +   + + K++K +E  E+++ ++ +S    +S  P +KKK
Sbjct: 1426 GTVEGGDQSNP------KSKKEKKKSDKRKKDKEKKEKKKKAKKASTK--DSESPSQKKK 1477

Query: 1401 IKKKK 1405
             KKKK
Sbjct: 1478 KKKKK 1482



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 57/262 (21%), Positives = 101/262 (38%), Gaps = 42/262 (16%)

Query: 639 SASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENS 698
           +A V++   E ++++S SE S     ++   N   +   G +   K A T   G   + +
Sbjct: 463 AAQVQVGKQEEDSRSS-SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521

Query: 699 HSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS 758
             +PP      VG + P +Q    +  S +S+E  +                SSD E+ +
Sbjct: 522 GPVPP----GKVGPATPSAQVGKWEEDSESSSEESSD---------------SSDGEVPT 562

Query: 759 AVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFK 818
           AV+    ++L  I+ + PT SP K           +  G V   +V     M+ S  + +
Sbjct: 563 AVAPAQEKSLGNILQAKPTSSPAK--------GPPQKAGPVA-VQVKAEKPMDNSESSEE 613

Query: 819 SEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTAL 878
           S DSA  +++       +A   P +         +P T      +N    A+    P  +
Sbjct: 614 SSDSA--DSEEAPAAMTAAQAKPALK--------IPQTKACPKKTNT--TASAKVAPVRV 661

Query: 879 GTSV-SQSNVVVLPGNSAPMTA 899
           GT    ++     P  S+P  A
Sbjct: 662 GTQAPRKAGTATSPAGSSPAVA 683


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
            sapiens]
          Length = 1411

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 130/708 (18%), Positives = 252/708 (35%), Gaps = 145/708 (20%)

Query: 647  TENEAQASKSENS---QEPSSSVKEENTIF-LSLGGNANCEKVALTPPEGTPVENSHSLP 702
            T  +AQ    E+S   +E S S +E  T+  +   G  +  + AL P + +P + +   P
Sbjct: 779  TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 838

Query: 703  PESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTSAVSS 762
            P       G S  ++   DD  SS+  ++                    SD E  +AV+S
Sbjct: 839  P----GKTGPSAAQAGKQDDSGSSSEESD--------------------SDGEAPAAVTS 874

Query: 763  INGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFKSEDS 822
                  P +I   P +SP                 A   A+   +++  ++  +  +  S
Sbjct: 875  AQVIK-PPLIFVDPNRSPAG--------------PAATPAQAQAASTPRKARASESTARS 919

Query: 823  AVNNTQNEDGIAFSANVTP-----CVSKDGGYIQLMPATSTAFGNSNNILIATCVTD--- 874
            + + +++ED I  +  +TP      V+    + ++ P  S A  +S+    ++ ++D   
Sbjct: 920  SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK--ESSRISDGKK 977

Query: 875  PTALGTSVSQSNVVVLPGNSAPM------TAQPLPPQLQTPPRS--NSVFAVNQAVSPNF 926
                 T VS+ N   LP   A +       ++  PP  +T P S  +S      A SP  
Sbjct: 978  QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQ- 1036

Query: 927  SQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMPLTAPVCNRSIPQFP 986
                                     SV  +  N    P    +     AP  +       
Sbjct: 1037 -----------------------STSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1073

Query: 987  VPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDKSIATDLGKKSEETTVP 1046
                  +  G   +             S H++G    +TE    ++  +   +S E  V 
Sbjct: 1074 DSSSGSEEDGEGPQGA----------KSAHTLGPTPSRTE----TLVEETAAESSEDDVV 1119

Query: 1047 FPEESIV---------PAAKPCHRRVLCFDST---TAPVANTQGPNHKMVSQNKERNAVS 1094
             P +S++         PA     +     DS+   ++ +A    P+ K  ++ ++   + 
Sbjct: 1120 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1179

Query: 1095 FPNLDSPNVSSTLKPPSNNAIKREKEKP------------------PLPKILSKSESAIS 1136
             P       +S   P  +   K+    P                  P P   ++ ++++ 
Sbjct: 1180 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1239

Query: 1137 RHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPEN-SKLSIGQQNGGL 1195
            +  T    Q  KKV  T    ES  K   +++ +L  D    + P +  K  +G   GG 
Sbjct: 1240 KVLTELLEQERKKVVDT--TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG- 1296

Query: 1196 RSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQEQTKSA--SSLITTEMLQDIQRH 1253
              E S++  +  T  +G +  +K       A  D+K+++ K +  S     E  +++Q+ 
Sbjct: 1297 --EASVSPEKTSTTSKGKAKRDK-------ASGDVKEKKGKGSLGSQGAKDEPEEELQKG 1347

Query: 1254 SSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSSRRFSEDSST 1301
                   D S+ P  +     + ++ K++     K  + +  ++DS +
Sbjct: 1348 MGTVEGGDQSN-PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1394



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 63/365 (17%), Positives = 135/365 (36%), Gaps = 45/365 (12%)

Query: 1068 STTAPVANTQGPNHKMVSQNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKI 1127
            +T AP ++    +    S   E +        S +        +   ++    +     +
Sbjct: 1059 ATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDV 1118

Query: 1128 LSKSESAISRHTTIRETQSEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLS 1187
            ++ S+S +S + T   T +  + S     L+S    ++    +   D +++  P+ +   
Sbjct: 1119 VAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGM 1178

Query: 1188 IGQQNGGLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKD--------LKQEQTKSAS 1239
            +  + GG  +       +    K+G  +   + L++ + +          L + Q +++ 
Sbjct: 1179 LSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1238

Query: 1240 SLITTEMLQDIQRHSSVSRLADSS-------------DLPVPRTPGS------GAGEKHK 1280
              + TE+L+  +R   V    +SS             D P  RTP S      GAGE  +
Sbjct: 1239 VKVLTELLEQ-ERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1297

Query: 1281 EEPIDIIKAPSSRRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSR 1340
                    A  S   +  +S  K      + D+         GS+ + +     L     
Sbjct: 1298 --------ASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ-KGM 1348

Query: 1341 AAISRTTSATPLKDNTQQFRASSRSTTKKRKIEELDERERNSRPSSKNLTNSSIPMKKKK 1400
              +     + P      + +   + + K++K +E  E+++ ++ +S    +S  P +KKK
Sbjct: 1349 GTVEGGDQSNP------KSKKEKKKSDKRKKDKEKKEKKKKAKKASTK--DSESPSQKKK 1400

Query: 1401 IKKKK 1405
             KKKK
Sbjct: 1401 KKKKK 1405



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 57/262 (21%), Positives = 101/262 (38%), Gaps = 42/262 (16%)

Query: 639 SASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENS 698
           +A V++   E ++++S SE S     ++   N   +   G +   K A T   G   + +
Sbjct: 386 AAQVQVGKQEEDSRSS-SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 444

Query: 699 HSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS 758
             +PP      VG + P +Q    +  S +S+E  +                SSD E+ +
Sbjct: 445 GPVPP----GKVGPATPSAQVGKWEEDSESSSEESSD---------------SSDGEVPT 485

Query: 759 AVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFK 818
           AV+    ++L  I+ + PT SP K           +  G V   +V     M+ S  + +
Sbjct: 486 AVAPAQEKSLGNILQAKPTSSPAK--------GPPQKAGPVA-VQVKAEKPMDNSESSEE 536

Query: 819 SEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTAL 878
           S DSA  +++       +A   P +         +P T      +N    A+    P  +
Sbjct: 537 SSDSA--DSEEAPAAMTAAQAKPALK--------IPQTKACPKKTNT--TASAKVAPVRV 584

Query: 879 GTSV-SQSNVVVLPGNSAPMTA 899
           GT    ++     P  S+P  A
Sbjct: 585 GTQAPRKAGTATSPAGSSPAVA 606



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 653 ASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPP---ESVCSS 709
           A ++++S E +SS  +E  + +         + A  P +GTP + +   PP    +V S 
Sbjct: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252

Query: 710 VGDSHPESQNTDDKPSSNNSAE 731
                PE  +      S++S E
Sbjct: 253 TKAGKPEEDSESSSEESSDSEE 274


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 40.4 bits (93), Expect = 0.012
 Identities = 175/1007 (17%), Positives = 344/1007 (34%), Gaps = 167/1007 (16%)

Query: 496  SESQLQPDQPDIPITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSN 555
            S S+   D  D  + + V+   E +  N++ +  +S      +   G P K         
Sbjct: 470  SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS------SPAKGPPQKAGPVAVQVK 523

Query: 556  DTVKLKINFHGSKSSDSSEVHKSKIEINVLE--PVMS--QLSNC--QDNSCLQSEILPVS 609
                +  +    +SSDS++  ++   +   +  P +   Q   C  + N+   +++ PV 
Sbjct: 524  AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583

Query: 610  VESSHLNVSGQVEIHLGDS---LSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSV 666
            V +     +G      G S      T++P+ DS+S E + +E E         Q  S   
Sbjct: 584  VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSV-- 641

Query: 667  KEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSS 726
                       G     K A  P +G+  + +  + P     +V     E Q   +    
Sbjct: 642  -----------GKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE 690

Query: 727  NNSAEIDASNIVSLKVIISDDPFVSSDT--ELTSAVSSINGEN-LPTIILSSPTKSPTKN 783
             + +E  A++   +K  +      ++       SA  +I+    + T    +  +SP+K 
Sbjct: 691  ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750

Query: 784  AELVKCLSSEETV--GAVVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTP 841
               V+   +   +  G      VG + +      T   EDS   +++ E      A    
Sbjct: 751  KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--SSEEESDSEEEAETLA 808

Query: 842  CVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSN--------------- 886
             V   G   Q+  A + A  +          T P   G S +Q+                
Sbjct: 809  QVKPSGKTHQIRAALAPAKESPRK---GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 865

Query: 887  ----------------VVVLPGNSAPMTAQPLPPQLQ---TPPRSNSVFAVNQAVSPNFS 927
                            ++ +  N +P      P Q Q   TP ++ +  +  ++ S    
Sbjct: 866  GEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 925

Query: 928  QGSAIIIASPVQPVLQGMVGMIPV---------SVVGQNGNNFST----------PPRQV 968
                I     + P ++  V  +P          S+ G + +  S+          P  QV
Sbjct: 926  DEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQV 985

Query: 969  LHM-PLTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIG--KQVNNLVDSSGHSVGCHAQKT 1025
                P + P+   ++          +    R +P  G    V  L  +S  S    A+ T
Sbjct: 986  SKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGT 1045

Query: 1026 EVSDKSIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVS 1085
               +K     L +  + T  P   +    ++          DS++    + +GP      
Sbjct: 1046 ---NKLRKPKLPEVQQATKAPESSDDSEDSS----------DSSSGSEEDGEGP------ 1086

Query: 1086 QNKERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQ 1145
                + A S   L  P  S T       A +  ++      +++ S+S +S + T   T 
Sbjct: 1087 ----QGAKSAHTLVGPTPSRTETLVEETAAESSEDD-----VVAPSQSLLSGYMTPGLTP 1137

Query: 1146 SEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSKLSIGQQNGGLRSEKSIASLQ 1205
            +  + S     L+S    ++    +   D +++  P+ +   +  + GG  +       +
Sbjct: 1138 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK 1197

Query: 1206 EMTKKQGTSSNNKNVLSVGTAVKD--------LKQEQTKSASSLITTEMLQDIQRHSSVS 1257
                K+G  +   + L++ + +          L + Q +++   + TE+L+  +R   V 
Sbjct: 1198 SRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQ-ERKKVVD 1256

Query: 1258 RLADSS-------------DLPVPRTPGS------GAGEKHKEEPIDIIKAPSSRRFSED 1298
               +SS             D P  RTP S      GAGE  +        A  S   +  
Sbjct: 1257 TTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE--------ASVSPEKTST 1308

Query: 1299 SSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSRAAISRTTSATPLKDNTQQ 1358
            +S  K      + D+         GS+ + +     L       +     + P      +
Sbjct: 1309 TSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGTVEGGDQSNP------K 1361

Query: 1359 FRASSRSTTKKRKIEELDERERNSRPSSKNLTNSSIPMKKKKIKKKK 1405
             +   + + K++K +E  E+++ ++ +S    +S  P +KKK KKKK
Sbjct: 1362 SKKEKKKSDKRKKDKEKKEKKKKAKKASTK--DSESPSQKKKKKKKK 1406



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 57/262 (21%), Positives = 101/262 (38%), Gaps = 42/262 (16%)

Query: 639 SASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENS 698
           +A V++   E ++++S SE S     ++   N   +   G +   K A T   G   + +
Sbjct: 386 AAQVQVGKQEEDSRSS-SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 444

Query: 699 HSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSLKVIISDDPFVSSDTELTS 758
             +PP      VG + P +Q    +  S +S+E  +                SSD E+ +
Sbjct: 445 GPVPP----GKVGPATPSAQVGKWEEDSESSSEESSD---------------SSDGEVPT 485

Query: 759 AVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGAVVYAEVGDSASMEQSLLTFK 818
           AV+    ++L  I+ + PT SP K           +  G V   +V     M+ S  + +
Sbjct: 486 AVAPAQEKSLGNILQAKPTSSPAK--------GPPQKAGPVA-VQVKAEKPMDNSESSEE 536

Query: 819 SEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPATSTAFGNSNNILIATCVTDPTAL 878
           S DSA  +++       +A   P +         +P T      +N    A+    P  +
Sbjct: 537 SSDSA--DSEEAPAAMTAAQAKPALK--------IPQTKACPKKTNT--TASAKVAPVRV 584

Query: 879 GTSV-SQSNVVVLPGNSAPMTA 899
           GT    ++     P  S+P  A
Sbjct: 585 GTQAPRKAGTATSPAGSSPAVA 606



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 653 ASKSENSQEPSSSVKEENTIFLSLGGNANCEKVALTPPEGTPVENSHSLPP---ESVCSS 709
           A ++++S E +SS  +E  + +         + A  P +GTP + +   PP    +V S 
Sbjct: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252

Query: 710 VGDSHPESQNTDDKPSSNNSAE 731
                PE  +      S++S E
Sbjct: 253 TKAGKPEEDSESSSEESSDSEE 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.122    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,464,942
Number of Sequences: 37866
Number of extensions: 2571927
Number of successful extensions: 10649
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 324
Number of HSP's that attempted gapping in prelim test: 9657
Number of HSP's gapped (non-prelim): 1175
length of query: 1427
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1312
effective length of database: 13,892,928
effective search space: 18227521536
effective search space used: 18227521536
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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