BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|154800453 tastin isoform 1 [Homo sapiens] (778 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|154800453 tastin isoform 1 [Homo sapiens] 1605 0.0 gi|154800455 tastin isoform 2 [Homo sapiens] 234 2e-61 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 67 8e-11 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 61 5e-09 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 61 5e-09 gi|47132519 Ras association and pleckstrin homology domains 1 is... 61 5e-09 gi|68563515 keratinocyte proline-rich protein [Homo sapiens] 61 5e-09 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 60 1e-08 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 60 1e-08 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 60 1e-08 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 60 1e-08 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 59 1e-08 gi|119943102 CREB binding protein isoform b [Homo sapiens] 58 4e-08 gi|119943104 CREB binding protein isoform a [Homo sapiens] 58 4e-08 gi|41281612 zinc finger protein 828 [Homo sapiens] 57 9e-08 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07 gi|150170670 piccolo isoform 2 [Homo sapiens] 54 4e-07 gi|150378539 piccolo isoform 1 [Homo sapiens] 54 4e-07 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 54 6e-07 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 54 6e-07 gi|153792074 proline rich 12 [Homo sapiens] 54 6e-07 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 53 9e-07 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 53 1e-06 gi|236459851 ubinuclein 2 [Homo sapiens] 52 2e-06 gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 52 2e-06 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 51 5e-06 gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 50 6e-06 gi|110349719 titin isoform N2-A [Homo sapiens] 50 8e-06 gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 49 2e-05 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 49 2e-05 >gi|154800453 tastin isoform 1 [Homo sapiens] Length = 778 Score = 1605 bits (4155), Expect = 0.0 Identities = 778/778 (100%), Positives = 778/778 (100%) Query: 1 MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR 60 MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR Sbjct: 1 MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR 60 Query: 61 PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEF 120 PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEF Sbjct: 61 PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEF 120 Query: 121 VADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTH 180 VADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTH Sbjct: 121 VADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTH 180 Query: 181 RLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRT 240 RLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRT Sbjct: 181 RLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRT 240 Query: 241 SVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSH 300 SVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSH Sbjct: 241 SVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSH 300 Query: 301 DSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM 360 DSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM Sbjct: 301 DSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM 360 Query: 361 PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPH 420 PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPH Sbjct: 361 PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPH 420 Query: 421 SNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLN 480 SNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLN Sbjct: 421 SNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLN 480 Query: 481 ATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQE 540 ATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQE Sbjct: 481 ATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQE 540 Query: 541 QLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIP 600 QLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIP Sbjct: 541 QLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIP 600 Query: 601 ESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPP 660 ESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPP Sbjct: 601 ESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPP 660 Query: 661 CCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLT 720 CCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLT Sbjct: 661 CCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLT 720 Query: 721 AIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP 778 AIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP Sbjct: 721 AIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP 778 >gi|154800455 tastin isoform 2 [Homo sapiens] Length = 144 Score = 234 bits (597), Expect = 2e-61 Identities = 115/121 (95%), Positives = 116/121 (95%), Gaps = 3/121 (2%) Query: 1 MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR 60 MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR Sbjct: 1 MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR 60 Query: 61 PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQT---EAPGT 117 PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQT APG Sbjct: 61 PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTVLVPAPGK 120 Query: 118 I 118 + Sbjct: 121 L 121 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 66.6 bits (161), Expect = 8e-11 Identities = 98/397 (24%), Positives = 124/397 (31%), Gaps = 112/397 (28%) Query: 305 MPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 MP P P PLP P P P G P PP T S LRR PK R + Sbjct: 1 MPVPPPPPPPLP----PPPPPLGAPPPPPPSAPPVSTDTSSLRR--ADPKGRSALLAD-- 52 Query: 365 RVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRT 424 +QQ LR V+ + P I S +G+ K + + ++ Sbjct: 53 -IQQGTRLRKVTQINDRSAPQ----------------IESSKGTNKEGGGSANTRGASTP 95 Query: 425 PSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQ------PLLTEISRT 478 P+L ++ +L+ +++V G GQ GS L PL+ S Sbjct: 96 PTLGDLFAGGFPVLRPAGQRDVAGGKTGQ----GPGSRAPSPRLPNKTISGPLIPPASPR 151 Query: 479 LNATEHNSGTSHL---------------------------------------PGLLKHSG 499 L T G + PG L Sbjct: 152 LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGN 211 Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPE-------PYPPAE 552 LP P C P P PP P PP P P L ++ P+ P PP Sbjct: 212 LPVVAPPVPCAPPPPPPPPPPTPP-------PLPPASVLSDKAVKPQLAPLHLPPIPP-- 262 Query: 553 PRPLESCC-----RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEI-----PES 602 P PL C ++EP P QE PPA P PL Y P P Sbjct: 263 PLPLLPPCGYPGLKAEPASPAQDAQE--------PPAPPPPLPPYASCSPRASLPAPPLP 314 Query: 603 SRQEQLEVPEPCPPAEPG----PLQPSTQGQSGPPGP 635 E P P PP P P + Q PP P Sbjct: 315 GVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP 351 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 60.8 bits (146), Expect = 5e-09 Identities = 159/659 (24%), Positives = 215/659 (32%), Gaps = 151/659 (22%) Query: 63 VDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEFVA 122 + + PR A TS R NP S RG+ PPA+ +PG + + Sbjct: 70 IPESAPRAGPTRSAGTSSR--------NPASRPPASGRGERA---PPAKNTSPGPVS--S 116 Query: 123 DPAALATILSGE-GVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHR 181 A T G G K + + ++A+ + R ++ P TP+ Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPA 175 Query: 182 LDPARASCFSR--LEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSR 239 + + + L P P R P S S S H +T PS RR +AG Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRK-SVSSASEHSTTEPSPAARRRPSAGGGL 234 Query: 240 TSVSQASGLLLETPVQ-PAFSLP--KGEREVVTHSDEG---GVASLGLAQRVPLRENREM 293 + S TP+ PA S P +G H + G+ +L Q P R++ Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-- 292 Query: 294 SHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQP 353 AP PL + PSP Q S PPTL + LT Q Sbjct: 293 ---------------APALGPLSSSPLATPSPSAALQ---SQAPPTLPATPHSSSLTCQ- 333 Query: 354 KTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQ--ESCIRSLEGSGKP 411 TP+P P A S Q+ PA P Q L ++ L Sbjct: 334 --LATPLPLAPPSPSAP----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387 Query: 412 PVAT--PSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQ 469 P+AT P P + P LQ P + +S L Sbjct: 388 PLATPPPQAPPALALPPLQ--------------------------APPSPPAS---PPLS 418 Query: 470 PLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECG-EPQPCPPAEPG--PPEAF 526 PL T + NA + LL+ P P P + P PP P PP Sbjct: 419 PLATPSPQAPNALAVH--------LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-- 468 Query: 527 CRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEP 586 ++ P + P LQ VP P PPA P P+ P+ P L++ +P P A P Sbjct: 469 -QAPPSLAAPPLQ----VP-PSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521 Query: 587 R----------------------------PLESYCRIEPEIPESSRQEQLEVPEPCPPAE 618 P+ P+ P L+VP P PPA Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPAS 580 Query: 619 P---GPLQPSTQGQ----SGP-------PGPCPRVELGASE----PCTLEHRSLESSLP 659 P P +P T G SGP PGP P S P H S +S P Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639 Score = 60.5 bits (145), Expect = 6e-09 Identities = 139/579 (24%), Positives = 189/579 (32%), Gaps = 113/579 (19%) Query: 106 PGPPAQTEAPGTIEFVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQ 165 P PP P + PAAL +L G +GR+P LA+R G GG T Sbjct: 27 PRPPGSPRPPPPVT----PAALR-VLGAAGA----VGRKP-LAERA---GGIGGATIPES 73 Query: 166 GVRA----SAYLAPRTPT---------HRLDPARASCFSRLEGPGPRGRTLCPQRLQALI 212 RA SA + R P R PA+ + + PG T P Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP------- 126 Query: 213 SPSGPSFHPSTRPSFQEL---RRETAGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVT 269 GP R S +E + T R+++S + P S R Sbjct: 127 ---GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183 Query: 270 HSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRA 329 ++ G A+ P E S + S S PSPA +P G + P+ + Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 330 QRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM----PSTPRVQQAQWLRG--VSPQSCSED 383 P + P R TP PS P+ + Q LR V+P Sbjct: 244 SSATPLSSPARSG----------PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 384 PAL-PWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLL 442 PAL P + + ++S + P P+ PHS+ + QL Sbjct: 294 PALGPLSSSPLATPSPSAALQS-----QAPPTLPATPHSS-------------SLTCQLA 335 Query: 443 RQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPK 502 +PL S LQ L + + + + G+ L HS LP Sbjct: 336 TP----------LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT--HSFLPS 383 Query: 503 PCLPEECGEPQPCPPA--------EPGPPEAFCRSEPEIPEPSLQEQLEV---------- 544 P L P PPA P PP + S P P L V Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443 Query: 545 PEP------YPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPE 598 P P PPA P P+ + P S L+VP P PPA P P+ P+ Sbjct: 444 PSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVP-PSPPASP-PMSPSATPPPQ 500 Query: 599 IPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCP 637 P L++ +P P A P P Q PP P Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 60.8 bits (146), Expect = 5e-09 Identities = 150/627 (23%), Positives = 211/627 (33%), Gaps = 110/627 (17%) Query: 65 SAGPRPKARHQAETSQRLVGISQPR-NPLEELRPSPRGQNVGPGPPAQTEAPGTIEFVAD 123 + G +P A + S PR P RP G+ PPA+ +PG + + Sbjct: 52 AVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGER-APPAKNTSPGPVS--SP 108 Query: 124 PAALATILSGE-GVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRL 182 A T G G K + + ++A+ + R ++ P TP+ + Sbjct: 109 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPAM 167 Query: 183 DPARASCFSR--LEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRT 240 + + L P P R P S S S H +T PS RR +AG Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRK-SVSSASEHSTTEPSPAARRRPSAGGGLQ 226 Query: 241 SVSQASGLLLETPV-QPAFSLP--KGEREVVTHSDE---GGVASLGLAQRVPLRENREMS 294 + S TP+ PA S P +G H + G+ +L Q P R Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR------ 280 Query: 295 HTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSP--GPPTLTSYSVLRRLTVQ 352 +D+ + S +P+A P P P PS Q +PSP PP+ + S L T+Q Sbjct: 281 --KDAAPALGPLSSSPLATPSPS-APPSPSAPPSLQTLPSPPATPPSQATTS-LGSPTLQ 336 Query: 353 PKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPP 412 F P P +SP + A P + L+ PP Sbjct: 337 ATHSFLPSPP------------LSPLATPPPQAPP-----------ALALPPLQAPPSPP 373 Query: 413 VATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLL 472 + P P + TPS Q + +LQ P + S P+ Sbjct: 374 ASPPLSPLA--TPSPQAPNALAVHLLQ---------------APFSPPPS------PPVQ 410 Query: 473 TEISRTLNATEHNSGT--SHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSE 530 S + S T S P L L P P PPA P P Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVP----------PSPPASP-PMSPSATPP 459 Query: 531 PEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLE 590 P+ P P L++ +P P A P ++ P P S + P P+ P+ Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ-----APFSPSASLPMS 514 Query: 591 SYCRIEPEIPESSRQEQLEVPEPCPPAEP---GPLQPSTQGQ----SGP-------PGPC 636 P+ P L+VP P PPA P P +P T G SGP PGP Sbjct: 515 PLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573 Query: 637 PRVELGASE----PCTLEHRSLESSLP 659 P S P H S +S P Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTP 600 Score = 60.5 bits (145), Expect = 6e-09 Identities = 129/553 (23%), Positives = 175/553 (31%), Gaps = 100/553 (18%) Query: 106 PGPPAQTEAPGTIEFVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQ 165 P PP P + PAAL +L G +GR+P LA+R G GG T Sbjct: 27 PRPPGSPRPPPPVT----PAALR-VLGAAGA----VGRKP-LAERA---GGIGGATIPES 73 Query: 166 GVRASAYLAPRTPT----HRLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHP 221 RA R P R PA+ + + PG T P GP Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP----------GPLGQK 123 Query: 222 STRPSFQEL---RRETAGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVAS 278 R S +E + T R+++S + P S R ++ G Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183 Query: 279 LGLAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPP 338 A+ P E S + S S PSPA +P G + P+ + P Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 Query: 339 TLTSYSVLRRLTVQPKTRFTPM-PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFD 397 + P R TP P+ P + + L+ + P QV D Sbjct: 244 ARSG----------PSARGTPRAPAHPSQPKPKGLQALRPP-----------QVTPPRKD 282 Query: 398 QESCIRSLEGSGKPPVATPSG---PHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQC 454 + L S P+ATPS P + PSLQ + Sbjct: 283 AAPALGPLSSS---PLATPSPSAPPSPSAPPSLQTLPSPPA------------------T 321 Query: 455 VPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQP 514 P +SL S TL AT + L L P L + P Sbjct: 322 PPSQATTSLG-----------SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 Query: 515 CPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEP----------RPLESCCRSEP 564 PPA P P P+ P L+ P PP+ P P+ Sbjct: 371 SPPASP-PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429 Query: 565 EIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQP 624 + P S L+VP P PPA P P+ P+ P L++ +P P A P P Sbjct: 430 QAPPSLAAPPLQVP-PSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487 Query: 625 STQGQSGPPGPCP 637 Q PP P Sbjct: 488 PLQALPSPPASFP 500 Score = 48.5 bits (114), Expect = 2e-05 Identities = 64/256 (25%), Positives = 85/256 (33%), Gaps = 49/256 (19%) Query: 473 TEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPE--AFCRSE 530 T +S + GT P H PKP + PQ PP + P S Sbjct: 238 TPLSSPARSGPSARGTPRAPA---HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294 Query: 531 PEIPEPSLQEQLEVPE-----PYPPAEP----------------------RPLESCCRSE 563 P PS P P PPA P PL Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354 Query: 564 PEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEP--GP 621 P+ P + L+ P P PPA P PL P+ P + L+ P PP+ P P Sbjct: 355 PQAPPALALPPLQAP-PSPPASP-PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 Query: 622 LQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLC 681 P P P + P +L L+ +PP PA+ + S+ P Sbjct: 413 FSPPASPPVSPSATPP-----SQAPPSLAAPPLQ--VPPS----PPASPPMSPSATPPPQ 461 Query: 682 ASPPICS--LQSLRPP 695 A PP+ + LQ +PP Sbjct: 462 APPPLAAPPLQLAKPP 477 Score = 45.8 bits (107), Expect = 2e-04 Identities = 63/225 (28%), Positives = 77/225 (34%), Gaps = 49/225 (21%) Query: 499 GLPKPCLPE-------ECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLE--VPEPYP 549 G P P + E G P+P P A P PP E P S+ E EP P Sbjct: 161 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-------TEGPRKSVSSASEHSTTEPSP 213 Query: 550 PAEPRPLESCCRSEPEIPE-SSRQEQLEVPE---PCPPAEPRPLESYCRIEPEIPESSRQ 605 A RP P SS L P P PR P P+ Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR-----APAHPSQPKPKGL 268 Query: 606 EQLEVPEPCPPAEP-----GPLQPS---TQGQSGPPGPCPRVELGASEPCTLEHRSLESS 657 + L P+ PP + GPL S T S PP P S P +L+ + Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP--------SAPPSLQTLPSPPA 320 Query: 658 LPPCCSQWAPATTSL---IFSSQHPLCASPPICSLQSLRPPAGQA 699 PP + ATTSL + H SPP+ L + P A A Sbjct: 321 TPP-----SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 60.8 bits (146), Expect = 5e-09 Identities = 63/239 (26%), Positives = 93/239 (38%), Gaps = 19/239 (7%) Query: 475 ISRTLNATEHNSGTSHLPGL-LKHSGLPKPCL---PEECGEPQPCPPAEPGPPEAFCRSE 530 I+R NA++H+ P + S KP + P P P PP P P A + + Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729 Query: 531 PEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPP-AEPRPL 589 P PSL + P PP + ++ + P P +P P PP A P+PL Sbjct: 730 PAPCAPSLP---QFSAPPPPLKIHQVQHITQVAPPTPPPPP----PIPAPLPPQAPPKPL 782 Query: 590 ESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTL 649 + + Q P P PP P QP+ PP P P + P Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP-PTPPVPVPPPTLP 841 Query: 650 EHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRT 708 + +S + PP P+ I +SQ P +PP Q L+P +N+AP++ Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQI-ASQFPPPPTPPAMESQPLKPVP-----ANVAPQS 894 Score = 50.4 bits (119), Expect = 6e-06 Identities = 103/437 (23%), Positives = 143/437 (32%), Gaps = 82/437 (18%) Query: 299 SHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGP--PTLTSYSVLRRL-TVQPKT 355 S S +P P P P P P P P +Q PS G P YS + RL + Sbjct: 622 SQPSPPLPPPPPPPPPPPPPPPPPPPPLP-SQSAPSAGSAAPMFVKYSTITRLQNASQHS 680 Query: 356 RFTPMPSTPRVQQAQWLRG---VSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPP 412 P TP V Q+Q ++ V P P P S KP Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP---------PPPPTPGSAMAQLKPA 731 Query: 413 VATPSGPHSNRTPSLQEVKIQRIGILQQLLRQE------VEGLVGGQCVPLNGGSSLDMV 466 PS P + P +KI ++ + Q+ + + Q P Sbjct: 732 PCAPSLPQFSAPPP--PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP---------- 779 Query: 467 ELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAF 526 +PL+T + T T T P P P P + QP PA PP Sbjct: 780 --KPLVTIPAPTSTKTVAPVVTQAAP--------PTPTPPVPPAKKQPAFPASYIPPSPP 829 Query: 527 CRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRS-EPEIPESSRQEQLEVPEPCPPA- 584 P +P P+L +Q PP+ P+ S + + P P P PPA Sbjct: 830 TPPVP-VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP----------PPPTPPAM 878 Query: 585 -----EPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRV 639 +P P + P + + + +P P P P P + S PP P P Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938 Query: 640 -------------ELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSS---QHPLCAS 683 + G+ T + S PP P S I SS +HP Sbjct: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP----TPQRNSSIKSSSGAEHPEPKR 994 Query: 684 PPICSLQSLRPPAGQAG 700 P + SL S P ++G Sbjct: 995 PSVDSLVSKFTPPAESG 1011 Score = 34.3 bits (77), Expect = 0.45 Identities = 72/312 (23%), Positives = 105/312 (33%), Gaps = 48/312 (15%) Query: 302 SHLMPSPAPVA------QPLPGHVVPCPSPFGRAQR--------VPSPGPPTLTSYSVLR 347 S P P P A +P+P +V P P +A+ VPSP P S L Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926 Query: 348 RLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEG 407 P P P P + SP + + P + + S I+S G Sbjct: 927 FPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986 Query: 408 SGKPPVATPSGPH--SNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDM 465 + P PS S TP + + E L P G +L Sbjct: 987 AEHPEPKRPSVDSLVSKFTPPAESGSPSK------------ETLPPPAAPPKPGKLNLSG 1034 Query: 466 VELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAE-PGPPE 524 V L +L + + A L G K S + P P + P P P E P PP Sbjct: 1035 VNLPGVLQQGCVSAKAPV-------LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPI 1087 Query: 525 AFC-----RSEPEI----PEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQL 575 + P++ P+P ++ V + PP P+ +S ++ EI S Q + Sbjct: 1088 EIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEI---SEQPTM 1144 Query: 576 EVPEPCPPAEPR 587 P P P+ Sbjct: 1145 ATVVPQVPTSPK 1156 Score = 30.0 bits (66), Expect = 8.6 Identities = 49/204 (24%), Positives = 77/204 (37%), Gaps = 19/204 (9%) Query: 174 APRTPTHRLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRE 233 A TP P + + S+ PG + PQR ++ S SG RPS L Sbjct: 946 ASPTPDKSGSPGKKT--SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL--- 1000 Query: 234 TAGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLG-LAQRVPLRENR- 291 S+ + SG + + P + PK + ++ + GV G ++ + P+ R Sbjct: 1001 ---VSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 Query: 292 ---EMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVP--SPGPPTLTSYSVL 346 + DS P P PLP +P + +V +P P + SV Sbjct: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117 Query: 347 RRLTVQPKTRFTPMPSTPRVQQAQ 370 + P TR ST R+ QA+ Sbjct: 1118 K---APPPTRPKRNDST-RLTQAE 1137 >gi|68563515 keratinocyte proline-rich protein [Homo sapiens] Length = 579 Score = 60.8 bits (146), Expect = 5e-09 Identities = 67/198 (33%), Positives = 75/198 (37%), Gaps = 29/198 (14%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFC--RSEPEIPEPSLQEQLEVPEPYPPAEPRPLES 558 P+P C P+ P EP P +FC R + PE LQ P P P RP E Sbjct: 359 PQPSWGASC--PELRPHVEPRPLPSFCPPRRLDQCPESPLQR---CPPPAPRPRLRP-EP 412 Query: 559 CCRSEPEIPESSRQ--EQLEVPEPCPPAEP--RPLESYCRIEPEIPESSRQEQ-LEVPEP 613 C EP RQ E PEP P P RP+ + EIPE Q E PEP Sbjct: 413 CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEP 472 Query: 614 CPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLI 673 CP EP PL P PCP + EPC RS P + P Sbjct: 473 CPRPEPIPL----------PAPCP-----SPEPCRETWRSPSPCWGPNPVPY-PGDLGCH 516 Query: 674 FSSQHPLCASPPICSLQS 691 SS H L P C S Sbjct: 517 ESSPHRLDTEAPYCGPSS 534 Score = 55.1 bits (131), Expect = 2e-07 Identities = 52/136 (38%), Positives = 57/136 (41%), Gaps = 20/136 (14%) Query: 500 LPKPCLP---EECGEP--QPCPPAEPGP---PEAFCRSEPEIPEP---SLQEQLEVPEPY 548 LP C P ++C E Q CPP P P PE EP P P L E PEP Sbjct: 379 LPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPR-PRPLPRQLSEPCLYPEPL 437 Query: 549 PPAEP--RPLESCCRSEPEIPESSRQEQ-LEVPEPCPPAEPRPLESYCRIEPEIPESSRQ 605 P P RP+ + EIPE Q E PEPCP EP PL + C PE R Sbjct: 438 PALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPC----PSPEPCR- 492 Query: 606 EQLEVPEPCPPAEPGP 621 E P PC P P Sbjct: 493 ETWRSPSPCWGPNPVP 508 Score = 46.2 bits (108), Expect = 1e-04 Identities = 57/176 (32%), Positives = 71/176 (40%), Gaps = 40/176 (22%) Query: 488 TSHLPGLLKHSGLPKPCLPEECGEP---QPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEV 544 +S+LP L G P C P EP CP P + C S+ P+ ++E+ Sbjct: 280 SSYLP-LRPSEGFPNYCTPPRRSEPIYNSRCPRR----PISSC-SQRRGPKC----RIEI 329 Query: 545 PEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPC---------PPAEPRPLESYC-- 593 P P + P R EIP R+ Q P+P P EPRPL S+C Sbjct: 330 SSPCCPRQVPPQ----RCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPP 385 Query: 594 RIEPEIPESSRQEQLEVPEPCPPAEPGP-LQPSTQGQSGP-PGPCPRVELGASEPC 647 R + PES Q CPP P P L+P P P P PR SEPC Sbjct: 386 RRLDQCPESPLQR-------CPPPAPRPRLRPEPCISLEPRPRPLPR---QLSEPC 431 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 59.7 bits (143), Expect = 1e-08 Identities = 85/400 (21%), Positives = 121/400 (30%), Gaps = 48/400 (12%) Query: 308 PAPVAQPLPGHVVP---CPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 P P P P P+ A P PT T + P T P P+TP Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275 Query: 365 RVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRT 424 + + +P + P P E P TP+ P Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 334 Query: 425 PSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEH 484 P+ +E ++ + P +P T T Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 394 Query: 485 NSGTSH---LPGLLKHSGL-PKPCLPEECGEPQPCPPAEPGP--PEAFCRSEPEIPEPSL 538 ++ T+ P K + PK P EP P P EP P P+ + P+ P P+ Sbjct: 395 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 454 Query: 539 QEQ-----LEVPEPYPPAEPRPL------------------ESCCRSEPEIPESSRQEQL 575 ++ + P P P EP P E + PE P + E+L Sbjct: 455 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 514 Query: 576 -----EVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 E P P P EP P P P+ + P P P EP P P + Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 573 Query: 631 GPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATT 670 P G + P TL+ + + P + AP TT Sbjct: 574 TPKG---------TAPTTLKEPAPTTPKKPAPKELAPTTT 604 Score = 58.5 bits (140), Expect = 2e-08 Identities = 50/189 (26%), Positives = 71/189 (37%), Gaps = 40/189 (21%) Query: 501 PKPCLPEECG-----EPQPCPPAEPGP--PEAFCRSEPEIPEPSLQEQLEVPEPYPPAEP 553 P P PEE EP P P EP P P+A + P+ P P+ ++ P P P EP Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE---PAPTTPKEP 562 Query: 554 RPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLE-----------SYC-RIEPEIPE 601 P + P P+ + L+ P P P +P P E + C + P P+ Sbjct: 563 APTTPK-ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621 Query: 602 SSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPC 661 + + P P P EP P P + P TL+ + + P Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPK-----------------GTAPTTLKEPAPTTPKKPA 664 Query: 662 CSQWAPATT 670 + AP TT Sbjct: 665 PKELAPTTT 673 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 511 EPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESS 570 EP P P EP + P+ P P+ + P P EP P + +S P P+ Sbjct: 215 EPTPTTPKEPAS------TTPKEPTPTTIKSA----PTTPKEPAPTTT--KSAPTTPKEP 262 Query: 571 RQEQLEVPEPCPPAEP------RPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQP 624 + P P P EP P + + P P+ + P P P EP P P Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 322 Query: 625 STQGQSGPPGPCP 637 + P P P Sbjct: 323 KEPTPTTPKEPAP 335 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/169 (24%), Positives = 56/169 (33%), Gaps = 38/169 (22%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK P EP P P EP P P+ + L+ P P P +P P E Sbjct: 620 PKGTAPTTPKEPAPTTPKEPA---------PTTPKGTAPTTLKEPAPTTPKKPAPKELA- 669 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 P + + P P P E P + P P P +P Sbjct: 670 ---PTTTKGPTSTTSDKPAPTTPKETAPTTP-----------------KEPAPTTPKKPA 709 Query: 621 PLQPSTQGQSGPPGPCPRVELGAS--EPCTLEHRSLESSLPPCCSQWAP 667 P P T PP V + EP T+ H+S + S P ++ P Sbjct: 710 PTTPET-----PPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTP 752 Score = 30.8 bits (68), Expect = 5.0 Identities = 89/422 (21%), Positives = 131/422 (31%), Gaps = 60/422 (14%) Query: 10 PLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQRPLVDSAGPR 69 P + +PT K P + + P PT ++P K P P P Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP----SPTTPKE-PA 389 Query: 70 PKARHQAETSQRLVGISQPRN-PLEELRPSPRGQNVGPGPPAQTE-APGTIEFVADPAAL 127 P A T+ + + ++ P PSP P P E AP T P Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTT------PKKP 442 Query: 128 ATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARA 187 A E + P+ K+ TT + AP TP +L P Sbjct: 443 APTTPKEPAPTTPKEPAPTTTKK------PAPTTPKEPAPTTPKETAPTTP-KKLTPTTP 495 Query: 188 SCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASG 247 + P T P+ L +P+ P T P A + T A Sbjct: 496 EKLAPTTPEKPAPTT--PEEL----APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP- 548 Query: 248 LLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPS 307 TP +PA + PK E T + G A L+E P+ Sbjct: 549 ---TTPKEPAPTTPK-EPAPTTPKETAPTTPKGTAP-TTLKE----------------PA 587 Query: 308 PAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQ 367 P +P P + P + + P P T P T P P+TP+ Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG--------TAPTTPKEPAPTTPKEP 639 Query: 368 QAQWLRGVSPQSCSED-PALPWEQVAVRLFDQESCIRSLEGSGKPPVATP--SGPHSNRT 424 +G +P + E P P + L + + S KP TP + P + + Sbjct: 640 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 699 Query: 425 PS 426 P+ Sbjct: 700 PA 701 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 59.7 bits (143), Expect = 1e-08 Identities = 85/400 (21%), Positives = 121/400 (30%), Gaps = 48/400 (12%) Query: 308 PAPVAQPLPGHVVP---CPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 P P P P P+ A P PT T + P T P P+TP Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316 Query: 365 RVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRT 424 + + +P + P P E P TP+ P Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 375 Query: 425 PSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEH 484 P+ +E ++ + P +P T T Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 435 Query: 485 NSGTSH---LPGLLKHSGL-PKPCLPEECGEPQPCPPAEPGP--PEAFCRSEPEIPEPSL 538 ++ T+ P K + PK P EP P P EP P P+ + P+ P P+ Sbjct: 436 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 495 Query: 539 QEQ-----LEVPEPYPPAEPRPL------------------ESCCRSEPEIPESSRQEQL 575 ++ + P P P EP P E + PE P + E+L Sbjct: 496 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 555 Query: 576 -----EVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 E P P P EP P P P+ + P P P EP P P + Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 614 Query: 631 GPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATT 670 P G + P TL+ + + P + AP TT Sbjct: 615 TPKG---------TAPTTLKEPAPTTPKKPAPKELAPTTT 645 Score = 58.5 bits (140), Expect = 2e-08 Identities = 50/189 (26%), Positives = 71/189 (37%), Gaps = 40/189 (21%) Query: 501 PKPCLPEECG-----EPQPCPPAEPGP--PEAFCRSEPEIPEPSLQEQLEVPEPYPPAEP 553 P P PEE EP P P EP P P+A + P+ P P+ ++ P P P EP Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE---PAPTTPKEP 603 Query: 554 RPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLE-----------SYC-RIEPEIPE 601 P + P P+ + L+ P P P +P P E + C + P P+ Sbjct: 604 APTTPK-ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662 Query: 602 SSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPC 661 + + P P P EP P P + P TL+ + + P Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPK-----------------GTAPTTLKEPAPTTPKKPA 705 Query: 662 CSQWAPATT 670 + AP TT Sbjct: 706 PKELAPTTT 714 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 511 EPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESS 570 EP P P EP + P+ P P+ + P P EP P + +S P P+ Sbjct: 256 EPTPTTPKEPAS------TTPKEPTPTTIKSA----PTTPKEPAPTTT--KSAPTTPKEP 303 Query: 571 RQEQLEVPEPCPPAEP------RPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQP 624 + P P P EP P + + P P+ + P P P EP P P Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 363 Query: 625 STQGQSGPPGPCP 637 + P P P Sbjct: 364 KEPTPTTPKEPAP 376 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/169 (24%), Positives = 56/169 (33%), Gaps = 38/169 (22%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK P EP P P EP P P+ + L+ P P P +P P E Sbjct: 661 PKGTAPTTPKEPAPTTPKEPA---------PTTPKGTAPTTLKEPAPTTPKKPAPKELA- 710 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 P + + P P P E P + P P P +P Sbjct: 711 ---PTTTKGPTSTTSDKPAPTTPKETAPTTP-----------------KEPAPTTPKKPA 750 Query: 621 PLQPSTQGQSGPPGPCPRVELGAS--EPCTLEHRSLESSLPPCCSQWAP 667 P P T PP V + EP T+ H+S + S P ++ P Sbjct: 751 PTTPET-----PPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTP 793 Score = 30.8 bits (68), Expect = 5.0 Identities = 89/422 (21%), Positives = 131/422 (31%), Gaps = 60/422 (14%) Query: 10 PLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQRPLVDSAGPR 69 P + +PT K P + + P PT ++P K P P P Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP----SPTTPKE-PA 430 Query: 70 PKARHQAETSQRLVGISQPRN-PLEELRPSPRGQNVGPGPPAQTE-APGTIEFVADPAAL 127 P A T+ + + ++ P PSP P P E AP T P Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTT------PKKP 483 Query: 128 ATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARA 187 A E + P+ K+ TT + AP TP +L P Sbjct: 484 APTTPKEPAPTTPKEPAPTTTKK------PAPTTPKEPAPTTPKETAPTTP-KKLTPTTP 536 Query: 188 SCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASG 247 + P T P+ L +P+ P T P A + T A Sbjct: 537 EKLAPTTPEKPAPTT--PEEL----APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP- 589 Query: 248 LLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPS 307 TP +PA + PK E T + G A L+E P+ Sbjct: 590 ---TTPKEPAPTTPK-EPAPTTPKETAPTTPKGTAP-TTLKE----------------PA 628 Query: 308 PAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQ 367 P +P P + P + + P P T P T P P+TP+ Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG--------TAPTTPKEPAPTTPKEP 680 Query: 368 QAQWLRGVSPQSCSED-PALPWEQVAVRLFDQESCIRSLEGSGKPPVATP--SGPHSNRT 424 +G +P + E P P + L + + S KP TP + P + + Sbjct: 681 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 740 Query: 425 PS 426 P+ Sbjct: 741 PA 742 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 59.7 bits (143), Expect = 1e-08 Identities = 85/400 (21%), Positives = 121/400 (30%), Gaps = 48/400 (12%) Query: 308 PAPVAQPLPGHVVP---CPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 P P P P P+ A P PT T + P T P P+TP Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368 Query: 365 RVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRT 424 + + +P + P P E P TP+ P Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 427 Query: 425 PSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEH 484 P+ +E ++ + P +P T T Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487 Query: 485 NSGTSH---LPGLLKHSGL-PKPCLPEECGEPQPCPPAEPGP--PEAFCRSEPEIPEPSL 538 ++ T+ P K + PK P EP P P EP P P+ + P+ P P+ Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547 Query: 539 QEQ-----LEVPEPYPPAEPRPL------------------ESCCRSEPEIPESSRQEQL 575 ++ + P P P EP P E + PE P + E+L Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607 Query: 576 -----EVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 E P P P EP P P P+ + P P P EP P P + Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 666 Query: 631 GPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATT 670 P G + P TL+ + + P + AP TT Sbjct: 667 TPKG---------TAPTTLKEPAPTTPKKPAPKELAPTTT 697 Score = 58.5 bits (140), Expect = 2e-08 Identities = 50/189 (26%), Positives = 71/189 (37%), Gaps = 40/189 (21%) Query: 501 PKPCLPEECG-----EPQPCPPAEPGP--PEAFCRSEPEIPEPSLQEQLEVPEPYPPAEP 553 P P PEE EP P P EP P P+A + P+ P P+ ++ P P P EP Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE---PAPTTPKEP 655 Query: 554 RPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLE-----------SYC-RIEPEIPE 601 P + P P+ + L+ P P P +P P E + C + P P+ Sbjct: 656 APTTPK-ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714 Query: 602 SSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPC 661 + + P P P EP P P + P TL+ + + P Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPK-----------------GTAPTTLKEPAPTTPKKPA 757 Query: 662 CSQWAPATT 670 + AP TT Sbjct: 758 PKELAPTTT 766 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 511 EPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESS 570 EP P P EP + P+ P P+ + P P EP P + +S P P+ Sbjct: 308 EPTPTTPKEPAS------TTPKEPTPTTIKSA----PTTPKEPAPTTT--KSAPTTPKEP 355 Query: 571 RQEQLEVPEPCPPAEP------RPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQP 624 + P P P EP P + + P P+ + P P P EP P P Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 415 Query: 625 STQGQSGPPGPCP 637 + P P P Sbjct: 416 KEPTPTTPKEPAP 428 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/169 (24%), Positives = 56/169 (33%), Gaps = 38/169 (22%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK P EP P P EP P P+ + L+ P P P +P P E Sbjct: 713 PKGTAPTTPKEPAPTTPKEPA---------PTTPKGTAPTTLKEPAPTTPKKPAPKELA- 762 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 P + + P P P E P + P P P +P Sbjct: 763 ---PTTTKGPTSTTSDKPAPTTPKETAPTTP-----------------KEPAPTTPKKPA 802 Query: 621 PLQPSTQGQSGPPGPCPRVELGAS--EPCTLEHRSLESSLPPCCSQWAP 667 P P T PP V + EP T+ H+S + S P ++ P Sbjct: 803 PTTPET-----PPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTP 845 Score = 30.8 bits (68), Expect = 5.0 Identities = 89/422 (21%), Positives = 131/422 (31%), Gaps = 60/422 (14%) Query: 10 PLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQRPLVDSAGPR 69 P + +PT K P + + P PT ++P K P P P Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP----SPTTPKE-PA 482 Query: 70 PKARHQAETSQRLVGISQPRN-PLEELRPSPRGQNVGPGPPAQTE-APGTIEFVADPAAL 127 P A T+ + + ++ P PSP P P E AP T P Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTT------PKKP 535 Query: 128 ATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARA 187 A E + P+ K+ TT + AP TP +L P Sbjct: 536 APTTPKEPAPTTPKEPAPTTTKK------PAPTTPKEPAPTTPKETAPTTP-KKLTPTTP 588 Query: 188 SCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASG 247 + P T P+ L +P+ P T P A + T A Sbjct: 589 EKLAPTTPEKPAPTT--PEEL----APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP- 641 Query: 248 LLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPS 307 TP +PA + PK E T + G A L+E P+ Sbjct: 642 ---TTPKEPAPTTPK-EPAPTTPKETAPTTPKGTAP-TTLKE----------------PA 680 Query: 308 PAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQ 367 P +P P + P + + P P T P T P P+TP+ Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG--------TAPTTPKEPAPTTPKEP 732 Query: 368 QAQWLRGVSPQSCSED-PALPWEQVAVRLFDQESCIRSLEGSGKPPVATP--SGPHSNRT 424 +G +P + E P P + L + + S KP TP + P + + Sbjct: 733 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792 Query: 425 PS 426 P+ Sbjct: 793 PA 794 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 59.7 bits (143), Expect = 1e-08 Identities = 85/400 (21%), Positives = 121/400 (30%), Gaps = 48/400 (12%) Query: 308 PAPVAQPLPGHVVP---CPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 P P P P P+ A P PT T + P T P P+TP Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409 Query: 365 RVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRT 424 + + +P + P P E P TP+ P Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 468 Query: 425 PSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEH 484 P+ +E ++ + P +P T T Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528 Query: 485 NSGTSH---LPGLLKHSGL-PKPCLPEECGEPQPCPPAEPGP--PEAFCRSEPEIPEPSL 538 ++ T+ P K + PK P EP P P EP P P+ + P+ P P+ Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588 Query: 539 QEQ-----LEVPEPYPPAEPRPL------------------ESCCRSEPEIPESSRQEQL 575 ++ + P P P EP P E + PE P + E+L Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648 Query: 576 -----EVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 E P P P EP P P P+ + P P P EP P P + Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 707 Query: 631 GPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATT 670 P G + P TL+ + + P + AP TT Sbjct: 708 TPKG---------TAPTTLKEPAPTTPKKPAPKELAPTTT 738 Score = 58.5 bits (140), Expect = 2e-08 Identities = 50/189 (26%), Positives = 71/189 (37%), Gaps = 40/189 (21%) Query: 501 PKPCLPEECG-----EPQPCPPAEPGP--PEAFCRSEPEIPEPSLQEQLEVPEPYPPAEP 553 P P PEE EP P P EP P P+A + P+ P P+ ++ P P P EP Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE---PAPTTPKEP 696 Query: 554 RPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLE-----------SYC-RIEPEIPE 601 P + P P+ + L+ P P P +P P E + C + P P+ Sbjct: 697 APTTPK-ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755 Query: 602 SSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPC 661 + + P P P EP P P + P TL+ + + P Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPK-----------------GTAPTTLKEPAPTTPKKPA 798 Query: 662 CSQWAPATT 670 + AP TT Sbjct: 799 PKELAPTTT 807 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 511 EPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESS 570 EP P P EP + P+ P P+ + P P EP P + +S P P+ Sbjct: 349 EPTPTTPKEPAS------TTPKEPTPTTIKSA----PTTPKEPAPTTT--KSAPTTPKEP 396 Query: 571 RQEQLEVPEPCPPAEP------RPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQP 624 + P P P EP P + + P P+ + P P P EP P P Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 456 Query: 625 STQGQSGPPGPCP 637 + P P P Sbjct: 457 KEPTPTTPKEPAP 469 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/169 (24%), Positives = 56/169 (33%), Gaps = 38/169 (22%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK P EP P P EP P P+ + L+ P P P +P P E Sbjct: 754 PKGTAPTTPKEPAPTTPKEPA---------PTTPKGTAPTTLKEPAPTTPKKPAPKELA- 803 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 P + + P P P E P + P P P +P Sbjct: 804 ---PTTTKGPTSTTSDKPAPTTPKETAPTTP-----------------KEPAPTTPKKPA 843 Query: 621 PLQPSTQGQSGPPGPCPRVELGAS--EPCTLEHRSLESSLPPCCSQWAP 667 P P T PP V + EP T+ H+S + S P ++ P Sbjct: 844 PTTPET-----PPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTP 886 Score = 30.8 bits (68), Expect = 5.0 Identities = 89/422 (21%), Positives = 131/422 (31%), Gaps = 60/422 (14%) Query: 10 PLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQRPLVDSAGPR 69 P + +PT K P + + P PT ++P K P P P Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP----SPTTPKE-PA 523 Query: 70 PKARHQAETSQRLVGISQPRN-PLEELRPSPRGQNVGPGPPAQTE-APGTIEFVADPAAL 127 P A T+ + + ++ P PSP P P E AP T P Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTT------PKKP 576 Query: 128 ATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARA 187 A E + P+ K+ TT + AP TP +L P Sbjct: 577 APTTPKEPAPTTPKEPAPTTTKK------PAPTTPKEPAPTTPKETAPTTP-KKLTPTTP 629 Query: 188 SCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASG 247 + P T P+ L +P+ P T P A + T A Sbjct: 630 EKLAPTTPEKPAPTT--PEEL----APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP- 682 Query: 248 LLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPS 307 TP +PA + PK E T + G A L+E P+ Sbjct: 683 ---TTPKEPAPTTPK-EPAPTTPKETAPTTPKGTAP-TTLKE----------------PA 721 Query: 308 PAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQ 367 P +P P + P + + P P T P T P P+TP+ Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG--------TAPTTPKEPAPTTPKEP 773 Query: 368 QAQWLRGVSPQSCSED-PALPWEQVAVRLFDQESCIRSLEGSGKPPVATP--SGPHSNRT 424 +G +P + E P P + L + + S KP TP + P + + Sbjct: 774 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833 Query: 425 PS 426 P+ Sbjct: 834 PA 835 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 59.3 bits (142), Expect = 1e-08 Identities = 83/339 (24%), Positives = 121/339 (35%), Gaps = 42/339 (12%) Query: 292 EMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTV 351 EM + ++ L P P P P +P PS P P PP V Sbjct: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPP------------V 436 Query: 352 QPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKP 411 P +P P + +Q + V P +CS P + R ++E+ EG+ P Sbjct: 437 SPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA-EREAARAGPEGT-SP 494 Query: 412 PVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQC--VPLNGGSSLDMVELQ 469 P TPS V + L+ +RQ + +V + V +D + Sbjct: 495 PTPTPSTATGGPPEDSPTVAPKSTTFLKN-IRQFIMPVVSARSSRVIKTPRRFMDEDPPK 553 Query: 470 PLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRS 529 P E+S L P + +P+ P P PP+ P P RS Sbjct: 554 PPKVEVSPVLR-----------PPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRS 602 Query: 530 ---EPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEP 586 EP SL +L P P PP P P S P P +S + L + P + Sbjct: 603 ILREPTFRWTSLTRELPPPPPAPPPPPAP------SPPPAPATSSRRPLLLRAP----QF 652 Query: 587 RPLESYCRIEPEIPESSRQEQLEVPEP-CPPAEPGPLQP 624 P E++ +I + E PEP PPA+ P +P Sbjct: 653 TPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEP 691 Score = 47.0 bits (110), Expect = 7e-05 Identities = 40/139 (28%), Positives = 46/139 (33%), Gaps = 28/139 (20%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 P P P P P PP PP C P P PP P PL S Sbjct: 403 PPPLTPPAPSPPPPLPPPSTSPPPPLC-----------------PPPPPPVSPPPLPS-- 443 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 P +++EQ E P P PA S R P + S R E+ E P Sbjct: 444 ----PPPPPAQEEQEESPPPVVPATC----SRKRGRPPLTPSQRAER-EAARAGPEGTSP 494 Query: 621 PLQPSTQGQSGPPGPCPRV 639 P + GPP P V Sbjct: 495 PTPTPSTATGGPPEDSPTV 513 Score = 38.9 bits (89), Expect = 0.018 Identities = 41/153 (26%), Positives = 49/153 (32%), Gaps = 29/153 (18%) Query: 506 PEECGEPQPCPP-AEPGPPE-----------------------AFCRSEPEIPEPSLQEQ 541 PE P P P A GPPE RS I P Sbjct: 489 PEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548 Query: 542 LEVPEPYPPAEPRP-LESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRI---EP 597 + P+P P E P L + P +P+ P PP+ P PL R EP Sbjct: 549 EDPPKP-PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607 Query: 598 EIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 +S +L P P PP P P P S Sbjct: 608 TFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS 640 Score = 34.7 bits (78), Expect = 0.35 Identities = 40/161 (24%), Positives = 56/161 (34%), Gaps = 28/161 (17%) Query: 559 CCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAE 618 C + + + + +E+ E E E + E E +P + ++E P P P Sbjct: 353 CWKKQEQKLDDEEEEKKEEEEKDKEGEEK--EERAVAEEMMPAAEKEEAKLPPPPLTPPA 410 Query: 619 PGPLQPSTQGQSGPPGP-CPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQ 677 P P P + PP P CP S P L S PP PA + Sbjct: 411 PSPPPPLPPPSTSPPPPLCPPPPPPVSPP------PLPSPPPP------PAQEE---QEE 455 Query: 678 HPLCASPPICSLQSLRPP----------AGQAGLSNLAPRT 708 P P CS + RPP A +AG +P T Sbjct: 456 SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT 496 Score = 34.3 bits (77), Expect = 0.45 Identities = 38/135 (28%), Positives = 44/135 (32%), Gaps = 25/135 (18%) Query: 516 PPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPR------PLESCCRSEPEIPES 569 PP P A P P +++VP P P PL S P P S Sbjct: 1843 PPLRPDSGSA----PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS-----PGSPSS 1893 Query: 570 SRQEQLEVPEPCPPAEPRPLESYCRIEPEIPES-------SRQEQLEVPEPCPPAEPGPL 622 V +P PA PR + P P S QL VP PP Sbjct: 1894 LTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP---PPTSVVTA 1950 Query: 623 QPSTQGQSGPPGPCP 637 T G+ PPGP P Sbjct: 1951 LTPTSGELAPPGPAP 1965 Score = 31.6 bits (70), Expect = 2.9 Identities = 33/117 (28%), Positives = 43/117 (36%), Gaps = 13/117 (11%) Query: 533 IPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQL-EVPEP--CPPAEPRPL 589 +P P L + P P PA R E R + E R+ Q + P C P+ PR Sbjct: 161 LPPPRLADVAPTP-PKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRS 219 Query: 590 ESYCRIEPEIPESSRQEQLEV---------PEPCPPAEPGPLQPSTQGQSGPPGPCP 637 P P +Q+ + V PEP PP P Q + PGP P Sbjct: 220 RGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGP 276 Score = 31.6 bits (70), Expect = 2.9 Identities = 42/160 (26%), Positives = 56/160 (35%), Gaps = 36/160 (22%) Query: 510 GEPQPCPPAEPGPPEAFCRSEPEI----PEPSLQ--EQLEVPEPYPPAEPRPLESCCRSE 563 GEP P P +P P + P P P L + V P PP P PL S Sbjct: 2208 GEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSG 2267 Query: 564 PEIP--ESSRQEQLEV------PEPCPPAEPRPLE-----------------SYCRIEPE 598 P P ++ R +++ P P P PR E + R+ + Sbjct: 2268 PASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMK 2327 Query: 599 IPESSRQEQLEVP-EPCPPAEPGPLQPSTQ----GQSGPP 633 P L+ P EP PGPLQ + + GPP Sbjct: 2328 TPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPP 2367 >gi|119943102 CREB binding protein isoform b [Homo sapiens] Length = 2404 Score = 57.8 bits (138), Expect = 4e-08 Identities = 59/225 (26%), Positives = 93/225 (41%), Gaps = 35/225 (15%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPA-EPRPLES 558 +P+ LP P P +P S P+ P+P Q P+P P + P S Sbjct: 1839 VPQQSLPSPTSAPPGTPTQQP--------STPQTPQPPAQ-----PQPSPVSMSPAGFPS 1885 Query: 559 CCRSEPEIPESSRQEQLEVPEPCPPAEPRP--LESYCRIEPEIPESSRQEQLEVPEPCPP 616 R++P S+ + +VP P PPA+P P +E+ +IE E + ++ + PP Sbjct: 1886 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1945 Query: 617 AEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSS 676 G P +Q V L P + + S+PP QW A Sbjct: 1946 GRTGMGTPGSQ--------MAPVSLNVPRPNQVS-GPVMPSMPP--GQWQQAP----LPQ 1990 Query: 677 QHPLCASP-PICSLQSLRPPAGQAGLSNLAPRTL---ALRERLKS 717 Q P+ P P+ S+Q+ AG S PR++ AL++ L++ Sbjct: 1991 QQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRT 2035 Score = 32.0 bits (71), Expect = 2.3 Identities = 58/245 (23%), Positives = 91/245 (37%), Gaps = 36/245 (14%) Query: 462 SLDMVELQ--PLLTEISRTLNATEHNSGTSHLPGL-LKHSGLPKPCLPEECGEPQPCPPA 518 SL V+L P+ + +N + + +PG+ + S +P+P P G A Sbjct: 690 SLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQP--PNMMGAHTNNMMA 747 Query: 519 EPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEV- 577 + F P+ PS + V PPA+ S+ ++P ++ L + Sbjct: 748 QAPAQSQFL---PQNQFPSSSGAMSVGMGQPPAQTGV------SQGQVPGAALPNPLNML 798 Query: 578 -PE----PCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEP---CPPAEPGPLQPST--- 626 P+ PCPP PL P ++ L+ P PP P QPST Sbjct: 799 GPQASQLPCPPVTQSPLHP---TPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVS 855 Query: 627 ---QGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQH---PL 680 Q + PG P S P T++ + P + P + + SSQ P+ Sbjct: 856 SSGQTPTPTPGSVPSATQTQSTP-TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV 914 Query: 681 CASPP 685 A PP Sbjct: 915 HAQPP 919 >gi|119943104 CREB binding protein isoform a [Homo sapiens] Length = 2442 Score = 57.8 bits (138), Expect = 4e-08 Identities = 59/225 (26%), Positives = 93/225 (41%), Gaps = 35/225 (15%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPA-EPRPLES 558 +P+ LP P P +P S P+ P+P Q P+P P + P S Sbjct: 1877 VPQQSLPSPTSAPPGTPTQQP--------STPQTPQPPAQ-----PQPSPVSMSPAGFPS 1923 Query: 559 CCRSEPEIPESSRQEQLEVPEPCPPAEPRP--LESYCRIEPEIPESSRQEQLEVPEPCPP 616 R++P S+ + +VP P PPA+P P +E+ +IE E + ++ + PP Sbjct: 1924 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1983 Query: 617 AEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSS 676 G P +Q V L P + + S+PP QW A Sbjct: 1984 GRTGMGTPGSQ--------MAPVSLNVPRPNQVS-GPVMPSMPP--GQWQQAP----LPQ 2028 Query: 677 QHPLCASP-PICSLQSLRPPAGQAGLSNLAPRTL---ALRERLKS 717 Q P+ P P+ S+Q+ AG S PR++ AL++ L++ Sbjct: 2029 QQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRT 2073 Score = 32.0 bits (71), Expect = 2.3 Identities = 58/245 (23%), Positives = 91/245 (37%), Gaps = 36/245 (14%) Query: 462 SLDMVELQ--PLLTEISRTLNATEHNSGTSHLPGL-LKHSGLPKPCLPEECGEPQPCPPA 518 SL V+L P+ + +N + + +PG+ + S +P+P P G A Sbjct: 728 SLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQP--PNMMGAHTNNMMA 785 Query: 519 EPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEV- 577 + F P+ PS + V PPA+ S+ ++P ++ L + Sbjct: 786 QAPAQSQFL---PQNQFPSSSGAMSVGMGQPPAQTGV------SQGQVPGAALPNPLNML 836 Query: 578 -PE----PCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEP---CPPAEPGPLQPST--- 626 P+ PCPP PL P ++ L+ P PP P QPST Sbjct: 837 GPQASQLPCPPVTQSPLHP---TPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVS 893 Query: 627 ---QGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQH---PL 680 Q + PG P S P T++ + P + P + + SSQ P+ Sbjct: 894 SSGQTPTPTPGSVPSATQTQSTP-TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV 952 Query: 681 CASPP 685 A PP Sbjct: 953 HAQPP 957 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 56.6 bits (135), Expect = 9e-08 Identities = 60/242 (24%), Positives = 85/242 (35%), Gaps = 43/242 (17%) Query: 489 SHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPE-- 546 SH P L P P P+P P+ PE+ + PEP E PE Sbjct: 231 SHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPW 290 Query: 547 -PYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQ 605 P+P P P R P + S +P PP PRP +S S+ Sbjct: 291 KPFPAVSPEPR----RPAPAVSPGSW-------KPGPPGSPRPWKS--------NPSASS 331 Query: 606 EQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLES--------- 656 + +P P PGP +P GP P P V + + ++ S +S Sbjct: 332 GPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWK 391 Query: 657 SLPPCCSQWAPATTSLIFSSQHPLC-----ASPPI-------CSLQSLRPPAGQAGLSNL 704 S PP + AP + + + P+ PP+ LR P+G L L Sbjct: 392 SGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKL 451 Query: 705 AP 706 +P Sbjct: 452 SP 453 Score = 42.0 bits (97), Expect = 0.002 Identities = 48/177 (27%), Positives = 64/177 (36%), Gaps = 22/177 (12%) Query: 464 DMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPP 523 D V+ PL N+ E S +P L + L E +P P P EP P Sbjct: 104 DPVKSPPLPEHQKIPCNSAEPKS----IPALSMETQKLGSVLSPESPKPTPLTPLEPQKP 159 Query: 524 EAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEP--EIPESSRQEQLEVPEPC 581 + E L+ P P P EP S EP +P Q+ VP P Sbjct: 160 GSVVSPE-----------LQTPLPSP--EPSKPASVSSPEPPKSVPVCESQKLAPVPSP- 205 Query: 582 PPAEPRPLESYCRIEPEIPESSRQEQLEVPEPC-PPAEPGPLQPSTQGQSGPPGPCP 637 P +P P+ S ++ + Q+Q PE PP+ P P P GP P Sbjct: 206 EPQKPAPV-SPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSP 261 Score = 36.6 bits (83), Expect = 0.092 Identities = 41/167 (24%), Positives = 59/167 (35%), Gaps = 24/167 (14%) Query: 488 TSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEP 547 TS P S P+P P P+P PA P ++ P P P P Sbjct: 274 TSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGP 333 Query: 548 YPPAEPRPLES-------------CCRSEPEIPESSRQEQLEVPE--PCPPAEPRPLESY 592 + PA+P P S + P + +S + P PPA P ES+ Sbjct: 334 WKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASP---ESW 390 Query: 593 CRIEPEIPESSRQEQLEVPEPCPPAEP------GPLQPSTQGQSGPP 633 PE+ +++ E + PP P PL P + +G P Sbjct: 391 KSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSP 437 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 55.5 bits (132), Expect = 2e-07 Identities = 173/776 (22%), Positives = 242/776 (31%), Gaps = 162/776 (20%) Query: 63 VDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEFVA 122 + + PR A TS R NP S RG+ PPA+ +PG + + Sbjct: 70 IPESAPRAGPTRSAGTSSR--------NPASRPPASGRGERA---PPAKNTSPGPVS--S 116 Query: 123 DPAALATILSGE-GVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHR 181 A T G G K + + ++A+ + R ++ P TP+ Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPA 175 Query: 182 LDPARASCFSR--LEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAG--- 236 + + + L P P R P S S S H +T PS RR +AG Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRK-SVSSASEHSTTEPSPAARRRPSAGGGL 234 Query: 237 ---SSRTSVSQASGLLL------------ETPVQPAFSLPKGEREV----VTHSDEGGVA 277 +SR+ S A+ L P P+ PKG + + VT + Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294 Query: 278 SLG---------------LAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPLPG----- 317 +LG A+ VP +N S + +P P+A P P Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354 Query: 318 HVVPCPSPFGRAQRVPS---------PGPPTLTSYSVLRRLTVQPKTRFTPMP------- 361 +P P +Q PS P T+ V LT P + P P Sbjct: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQ 413 Query: 362 -----STPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATP 416 +P +Q +SP+ P + A D L PP+ T Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSP-SRPASTPPDSPPLQAPLSLPASPPLQTS 472 Query: 417 SGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVP-LNGGSSLDMVELQ------ 469 P + P + I + L L + + +P L SSL LQ Sbjct: 473 LSPAVS--PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530 Query: 470 -------------PLLTEISRTLNATEHNSGTSHLPGLLKHSG----LPKPCLPEECGEP 512 P L S L + P L+ P P P P Sbjct: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590 Query: 513 QP-CPPAEPGPPEAFCRSEP----EIPEPSLQEQLEVPE----PYPPAEPRPLESCCRSE 563 P PPA PP S P P P L +P P PPA P PL Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP-PLSPLATPS 649 Query: 564 PEIPESSRQEQLEVPEPCPPAEP----------RPLESYCRIEPEIPESSRQEQLEVPEP 613 P+ P + L+ P PP+ P P+ + P S L+VP P Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-P 708 Query: 614 CPPAEPG-----------------------PLQPSTQGQSGPPGPCPRVELGASEPCTLE 650 PPA P P P++ S P PRV + P Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768 Query: 651 HRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAP 706 S +SLP P P A+PP+ +L S PPA G + +P Sbjct: 769 PPSPPASLPMSPLAKPPPQAP-------PALATPPLQALPS--PPASFPGQAPFSP 815 Score = 46.2 bits (108), Expect = 1e-04 Identities = 74/276 (26%), Positives = 93/276 (33%), Gaps = 65/276 (23%) Query: 499 GLPKPCLPE-------ECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLE--VPEPYP 549 G P P + E G P+P P A P PP E P S+ E EP P Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-------TEGPRKSVSSASEHSTTEPSP 222 Query: 550 PAEPR--------------------PLESCCRS------------EPEIPESSRQEQLEV 577 A R PL S RS P P+ + L Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282 Query: 578 PEPCPPAEPR-----PLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGP 632 P+ PP + PL S P P ++ + P+ P L PS P Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPS-PSGTKARPVPPPDNAATPLPATLPPS------P 335 Query: 633 P--GPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQ 690 P P P S P +L+ + PP SQ P+ T+ + L PPI Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPP--SQAPPSMTTPPMQAPPSLQTIPPIQVPH 393 Query: 691 SLRPPAGQAGLSNLAPRTLALRERLKS-CLTAIHCF 725 SL P+ QA S LA +L L S L A H F Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 54.3 bits (129), Expect = 4e-07 Identities = 112/513 (21%), Positives = 168/513 (32%), Gaps = 100/513 (19%) Query: 269 THSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPA--PVAQPLPGHVVPCPSPF 326 T + + A L L + + ++ R +PSP+ P+ QP PG P P Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP-PAQQP- 319 Query: 327 GRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM--PST--PRVQQAQWLRGVSPQSCSE 382 G + P P P + + L QP T P+ P T P Q + + Q+ SE Sbjct: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSE 379 Query: 383 DPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLL 442 P+ EQ + Q G GK P P GP T Q++G + L Sbjct: 380 KPSS--EQPGPKALAQP------PGVGKTPAQQP-GPAKPPT--------QQVGTPKPLA 422 Query: 443 RQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPK 502 +Q PGL + P Sbjct: 423 QQ-----------------------------------------------PGLQSPAKAPG 435 Query: 503 PC-LPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCR 561 P P + P P + GP + + PS QL P PP +P P + Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS---QLPGPAKPPPQQPGP----AK 488 Query: 562 SEPEIPESSR--QEQLEVPEPCP----PAEPRPLESYCRIEPEIPESSRQEQLEVPEPCP 615 P+ P S++ +Q +P P PA+P P + P S + + P P Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548 Query: 616 PAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIF- 674 P+ +P +Q SG P P V A +P + L ++ P C+ TT L+ Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP---PSQGLPKTICPLCN-----TTELLLH 600 Query: 675 ---SSQHPLC--ASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLTAIHCFHEAR 729 + C +CSL P + ++ L L + + + Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660 Query: 730 LDDECAFYTSRAPPSGPTRVCTNPVATLLEWQD 762 L TS S P T+P QD Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693 Score = 51.2 bits (121), Expect = 4e-06 Identities = 144/663 (21%), Positives = 220/663 (33%), Gaps = 83/663 (12%) Query: 28 KRTPFPTVTSCAVDQENQDPRRWV----QKPPLNIQRPLVDSAGPRPKARHQAETSQRLV 83 K PF ++ QE ++ V Q P I +P + P+P + Q L Sbjct: 172 KFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQ 231 Query: 84 GISQPRNPLEELRPSPRGQNVGPGPPAQ--TEAPGT----IEFVADPA----ALATILSG 133 P++ + + Q G G P Q T+ P T + D + A I+ G Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291 Query: 134 EGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARASCFSR- 192 E VK PS +K + + + G + G S P PA+ S ++ Sbjct: 292 ESVKP----SLPSPSKPPIQQPTPGKPPAQQPGHEKS------QPGPAKPPAQPSGLTKP 341 Query: 193 -LEGPG-------PRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQ 244 + PG P G T P + P GP+ P+ + ++ E G + Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQ------PLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395 Query: 245 ASGLLLETPVQPAFSLPKGEREVVTH---SDEGGVASLGLA---QRVPLRE----NREMS 294 G +TP Q ++V T + + G+ S A + P+++ Sbjct: 396 GVG---KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452 Query: 295 HTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPK 354 S P LPG P P G A+ P P P + + +P Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK--PPPQQPGSAKPPSQQPGSTKPP 510 Query: 355 TRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVA 414 + P P+ P QQ + S Q S P+ A Q + S GSGKP Sbjct: 511 PQ-QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569 Query: 415 TPSGPHSNRTPSLQEVK-IQRIGILQQLLRQEVEGLVGGQCVPLNGG-SSLDMVELQPLL 472 P + + PS K I + +LL E C SL P L Sbjct: 570 PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHL 629 Query: 473 TEI----------SRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGP 522 TE+ R L +S P L + + +PQ P + Sbjct: 630 TEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689 Query: 523 PEAFCRSEPE-------IPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQL 575 P+ PE + +P+L PP + EP +P + + Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749 Query: 576 EVPEPCPPAEPRPL-----ESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 +P P +P S +P+IP S Q Q E + PP + +PS QS Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPS---QS 805 Query: 631 GPP 633 PP Sbjct: 806 FPP 808 Score = 42.7 bits (99), Expect = 0.001 Identities = 142/684 (20%), Positives = 216/684 (31%), Gaps = 133/684 (19%) Query: 5 QATKDPLLRGVS-----PTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQ 59 Q + ++RG S P+PSK P+ Q+ TP +++Q P + Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPI--QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339 Query: 60 RPLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIE 119 +PL G T++ P P + S + + PGP A + PG + Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399 Query: 120 FVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPT 179 A +QP AK + + G+++ A T T Sbjct: 400 TPA--------------------QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Query: 180 HRLDPARASCFSRLEGPGPR-----GRTLCPQRLQALISPSGPSFHPSTRPSFQELRRET 234 P ++ GPG G T P +L GP+ P +P + + Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP------GPAKPPPQQPGPAKPPPQQ 493 Query: 235 AGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVTH--SDEGGVASLGLAQRVPLRENRE 292 GS++ SQ G P QP + P ++ T S + G A Q P + + + Sbjct: 494 PGSAKPP-SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552 Query: 293 MSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQ 352 S PV+Q G + P+ A++ PS G P T+ Sbjct: 553 QS-------------TKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK----------TIC 589 Query: 353 PKTRFTPM----PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGS 408 P T + P + C +P +V L R+L G Sbjct: 590 PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649 Query: 409 GKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVEL 468 P PS P P L+ + + + Q + P S + Sbjct: 650 LAP---VPSSPQ----PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702 Query: 469 QPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCR 528 P L + T H S ++ +P PE +P PP EP P Sbjct: 703 PPPLVK-----QPTLHGSPSAKAK---------QP--PEADSLSKPAPPKEPSVP----- 741 Query: 529 SEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPP----- 583 SE + P ++ + P+ P S ++P+IP S Q Q E + PP Sbjct: 742 SEQD-KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDS 799 Query: 584 --------------------AEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQ 623 A PRP I P S + Q +V EP Q Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859 Query: 624 ----------PSTQGQSGPPGPCP 637 P +G PPGP P Sbjct: 860 TKMSPKPDAKPMPKGSPTPPGPRP 883 Score = 39.3 bits (90), Expect = 0.014 Identities = 106/478 (22%), Positives = 166/478 (34%), Gaps = 95/478 (19%) Query: 285 VPLRENREMSHTRDSHDSHLMPSPAPVAQPLP--GHVVPCPSPFGRAQRVPSPGPPTLTS 342 + L+E++ + ++ H S +MP L VV +PF + T Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192 Query: 343 YSVLRRLTVQPKTRFTP-------------------------MPSTPRVQQAQWLRGVSP 377 V+++ +P+ P P + QQ + ++ P Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252 Query: 378 ------QSCSEDP-----ALPWEQVAVR-------LFDQESCIRSLEGSGKPPV--ATPS 417 Q ++ P LP ++ A R + ES SL KPP+ TP Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312 Query: 418 GP------HSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPL 471 P H P + Q G+ + L +Q G P QP Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP------GTVKPPVQPPGTTKPPAQP- 365 Query: 472 LTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEP 531 L T +S PG L +P + QP PA+P P + +P Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPG---PKALAQPPGVGKTPAQQP-GPAKP-PTQQVGTPKP 420 Query: 532 EIPEPSLQEQLEVPEP--YPPAEPRPLESCCRSEPEIPESSRQ-------EQLEVPEPCP 582 +P LQ + P P P +P P + + S++Q QL P P Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480 Query: 583 PAEPRPLESYCRIEPEIPESSR--QEQLEVPEPCPPAEPGPLQPSTQ--GQSGPPGPCPR 638 P +P P + P+ P S++ +Q +P PP +PGP +PS Q G + PP P Sbjct: 481 PQQPGP----AKPPPQQPGSAKPPSQQPGSTKP-PPQQPGPAKPSPQQPGSTKPPSQQP- 534 Query: 639 VELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPA 696 G+++P + S P Q + S PL PP S + +PP+ Sbjct: 535 ---GSAKPSAQQ----PSPAKPSAQQSTKPVSQT--GSGKPL--QPPTVSPSAKQPPS 581 Score = 35.0 bits (79), Expect = 0.27 Identities = 53/208 (25%), Positives = 79/208 (37%), Gaps = 31/208 (14%) Query: 507 EECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPR-PLESCCRSEPE 565 EE + Q E G PE I +P LQ+Q P P R PL+ + Sbjct: 187 EETTKKQKVVQKEQGKPEG-------IIKPPLQQQPPKPIPKQQGPGRDPLQ-----QDG 234 Query: 566 IPESSRQEQLEVPEPCPPAEPRPLESYCRI----EPEIP-------ESSRQEQLEVPEPC 614 P+S +Q E + PP +P++ + ++P ++Q + E Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294 Query: 615 PPAEPGPLQPSTQGQSGPPGPCPRVELG--ASEPCTLEHRSLESSLPPCCSQWAPATTSL 672 P+ P P +P Q + PG P + G S+P + + S L +Q P T Sbjct: 295 KPSLPSPSKPPIQQPT--PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQ-QPGTVKP 351 Query: 673 IFSSQHPLCASPPICSLQSLRPPAGQAG 700 Q P PP L +PPA Q G Sbjct: 352 --PVQPPGTTKPPAQPLGPAKPPAQQTG 377 Score = 31.6 bits (70), Expect = 2.9 Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 18/149 (12%) Query: 496 KHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRP 555 + S L P P P PP P PP P P+P++ + ++ P P Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454 Query: 556 LESCCRSEPEIPESSRQEQLEVPEPC----PPAEPRP------LESYCRIEPEIPESSRQ 605 L + E R L V C PP P+P L R EP P + Sbjct: 2455 LFDAV-TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIA-- 2511 Query: 606 EQLEVPEPCPPAEPGPLQPSTQGQSGPPG 634 P+P P P Q T P G Sbjct: 2512 -----PKPVIPQLPTTTQKPTDIHPKPTG 2535 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 54.3 bits (129), Expect = 4e-07 Identities = 112/513 (21%), Positives = 168/513 (32%), Gaps = 100/513 (19%) Query: 269 THSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPA--PVAQPLPGHVVPCPSPF 326 T + + A L L + + ++ R +PSP+ P+ QP PG P P Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP-PAQQP- 319 Query: 327 GRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM--PST--PRVQQAQWLRGVSPQSCSE 382 G + P P P + + L QP T P+ P T P Q + + Q+ SE Sbjct: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSE 379 Query: 383 DPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLL 442 P+ EQ + Q G GK P P GP T Q++G + L Sbjct: 380 KPSS--EQPGPKALAQP------PGVGKTPAQQP-GPAKPPT--------QQVGTPKPLA 422 Query: 443 RQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPK 502 +Q PGL + P Sbjct: 423 QQ-----------------------------------------------PGLQSPAKAPG 435 Query: 503 PC-LPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCR 561 P P + P P + GP + + PS QL P PP +P P + Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS---QLPGPAKPPPQQPGP----AK 488 Query: 562 SEPEIPESSR--QEQLEVPEPCP----PAEPRPLESYCRIEPEIPESSRQEQLEVPEPCP 615 P+ P S++ +Q +P P PA+P P + P S + + P P Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548 Query: 616 PAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIF- 674 P+ +P +Q SG P P V A +P + L ++ P C+ TT L+ Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP---PSQGLPKTICPLCN-----TTELLLH 600 Query: 675 ---SSQHPLC--ASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLTAIHCFHEAR 729 + C +CSL P + ++ L L + + + Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660 Query: 730 LDDECAFYTSRAPPSGPTRVCTNPVATLLEWQD 762 L TS S P T+P QD Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693 Score = 51.2 bits (121), Expect = 4e-06 Identities = 144/663 (21%), Positives = 220/663 (33%), Gaps = 83/663 (12%) Query: 28 KRTPFPTVTSCAVDQENQDPRRWV----QKPPLNIQRPLVDSAGPRPKARHQAETSQRLV 83 K PF ++ QE ++ V Q P I +P + P+P + Q L Sbjct: 172 KFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQ 231 Query: 84 GISQPRNPLEELRPSPRGQNVGPGPPAQ--TEAPGT----IEFVADPA----ALATILSG 133 P++ + + Q G G P Q T+ P T + D + A I+ G Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291 Query: 134 EGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARASCFSR- 192 E VK PS +K + + + G + G S P PA+ S ++ Sbjct: 292 ESVKP----SLPSPSKPPIQQPTPGKPPAQQPGHEKS------QPGPAKPPAQPSGLTKP 341 Query: 193 -LEGPG-------PRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQ 244 + PG P G T P + P GP+ P+ + ++ E G + Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQ------PLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395 Query: 245 ASGLLLETPVQPAFSLPKGEREVVTH---SDEGGVASLGLA---QRVPLRE----NREMS 294 G +TP Q ++V T + + G+ S A + P+++ Sbjct: 396 GVG---KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452 Query: 295 HTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPK 354 S P LPG P P G A+ P P P + + +P Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK--PPPQQPGSAKPPSQQPGSTKPP 510 Query: 355 TRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVA 414 + P P+ P QQ + S Q S P+ A Q + S GSGKP Sbjct: 511 PQ-QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569 Query: 415 TPSGPHSNRTPSLQEVK-IQRIGILQQLLRQEVEGLVGGQCVPLNGG-SSLDMVELQPLL 472 P + + PS K I + +LL E C SL P L Sbjct: 570 PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHL 629 Query: 473 TEI----------SRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGP 522 TE+ R L +S P L + + +PQ P + Sbjct: 630 TEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689 Query: 523 PEAFCRSEPE-------IPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQL 575 P+ PE + +P+L PP + EP +P + + Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749 Query: 576 EVPEPCPPAEPRPL-----ESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 +P P +P S +P+IP S Q Q E + PP + +PS QS Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPS---QS 805 Query: 631 GPP 633 PP Sbjct: 806 FPP 808 Score = 42.7 bits (99), Expect = 0.001 Identities = 142/684 (20%), Positives = 216/684 (31%), Gaps = 133/684 (19%) Query: 5 QATKDPLLRGVS-----PTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQ 59 Q + ++RG S P+PSK P+ Q+ TP +++Q P + Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPI--QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339 Query: 60 RPLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIE 119 +PL G T++ P P + S + + PGP A + PG + Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399 Query: 120 FVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPT 179 A +QP AK + + G+++ A T T Sbjct: 400 TPA--------------------QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Query: 180 HRLDPARASCFSRLEGPGPR-----GRTLCPQRLQALISPSGPSFHPSTRPSFQELRRET 234 P ++ GPG G T P +L GP+ P +P + + Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP------GPAKPPPQQPGPAKPPPQQ 493 Query: 235 AGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVTH--SDEGGVASLGLAQRVPLRENRE 292 GS++ SQ G P QP + P ++ T S + G A Q P + + + Sbjct: 494 PGSAKPP-SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552 Query: 293 MSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQ 352 S PV+Q G + P+ A++ PS G P T+ Sbjct: 553 QS-------------TKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK----------TIC 589 Query: 353 PKTRFTPM----PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGS 408 P T + P + C +P +V L R+L G Sbjct: 590 PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649 Query: 409 GKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVEL 468 P PS P P L+ + + + Q + P S + Sbjct: 650 LAP---VPSSPQ----PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702 Query: 469 QPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCR 528 P L + T H S ++ +P PE +P PP EP P Sbjct: 703 PPPLVK-----QPTLHGSPSAKAK---------QP--PEADSLSKPAPPKEPSVP----- 741 Query: 529 SEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPP----- 583 SE + P ++ + P+ P S ++P+IP S Q Q E + PP Sbjct: 742 SEQD-KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDS 799 Query: 584 --------------------AEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQ 623 A PRP I P S + Q +V EP Q Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859 Query: 624 ----------PSTQGQSGPPGPCP 637 P +G PPGP P Sbjct: 860 TKMSPKPDAKPMPKGSPTPPGPRP 883 Score = 39.3 bits (90), Expect = 0.014 Identities = 106/478 (22%), Positives = 166/478 (34%), Gaps = 95/478 (19%) Query: 285 VPLRENREMSHTRDSHDSHLMPSPAPVAQPLP--GHVVPCPSPFGRAQRVPSPGPPTLTS 342 + L+E++ + ++ H S +MP L VV +PF + T Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192 Query: 343 YSVLRRLTVQPKTRFTP-------------------------MPSTPRVQQAQWLRGVSP 377 V+++ +P+ P P + QQ + ++ P Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252 Query: 378 ------QSCSEDP-----ALPWEQVAVR-------LFDQESCIRSLEGSGKPPV--ATPS 417 Q ++ P LP ++ A R + ES SL KPP+ TP Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312 Query: 418 GP------HSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPL 471 P H P + Q G+ + L +Q G P QP Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP------GTVKPPVQPPGTTKPPAQP- 365 Query: 472 LTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEP 531 L T +S PG L +P + QP PA+P P + +P Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPG---PKALAQPPGVGKTPAQQP-GPAKP-PTQQVGTPKP 420 Query: 532 EIPEPSLQEQLEVPEP--YPPAEPRPLESCCRSEPEIPESSRQ-------EQLEVPEPCP 582 +P LQ + P P P +P P + + S++Q QL P P Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480 Query: 583 PAEPRPLESYCRIEPEIPESSR--QEQLEVPEPCPPAEPGPLQPSTQ--GQSGPPGPCPR 638 P +P P + P+ P S++ +Q +P PP +PGP +PS Q G + PP P Sbjct: 481 PQQPGP----AKPPPQQPGSAKPPSQQPGSTKP-PPQQPGPAKPSPQQPGSTKPPSQQP- 534 Query: 639 VELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPA 696 G+++P + S P Q + S PL PP S + +PP+ Sbjct: 535 ---GSAKPSAQQ----PSPAKPSAQQSTKPVSQT--GSGKPL--QPPTVSPSAKQPPS 581 Score = 35.0 bits (79), Expect = 0.27 Identities = 53/208 (25%), Positives = 79/208 (37%), Gaps = 31/208 (14%) Query: 507 EECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPR-PLESCCRSEPE 565 EE + Q E G PE I +P LQ+Q P P R PL+ + Sbjct: 187 EETTKKQKVVQKEQGKPEG-------IIKPPLQQQPPKPIPKQQGPGRDPLQ-----QDG 234 Query: 566 IPESSRQEQLEVPEPCPPAEPRPLESYCRI----EPEIP-------ESSRQEQLEVPEPC 614 P+S +Q E + PP +P++ + ++P ++Q + E Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294 Query: 615 PPAEPGPLQPSTQGQSGPPGPCPRVELG--ASEPCTLEHRSLESSLPPCCSQWAPATTSL 672 P+ P P +P Q + PG P + G S+P + + S L +Q P T Sbjct: 295 KPSLPSPSKPPIQQPT--PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQ-QPGTVKP 351 Query: 673 IFSSQHPLCASPPICSLQSLRPPAGQAG 700 Q P PP L +PPA Q G Sbjct: 352 --PVQPPGTTKPPAQPLGPAKPPAQQTG 377 Score = 31.6 bits (70), Expect = 2.9 Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 18/149 (12%) Query: 496 KHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRP 555 + S L P P P PP P PP P P+P++ + ++ P P Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454 Query: 556 LESCCRSEPEIPESSRQEQLEVPEPC----PPAEPRP------LESYCRIEPEIPESSRQ 605 L + E R L V C PP P+P L R EP P + Sbjct: 2455 LFDAV-TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIA-- 2511 Query: 606 EQLEVPEPCPPAEPGPLQPSTQGQSGPPG 634 P+P P P Q T P G Sbjct: 2512 -----PKPVIPQLPTTTQKPTDIHPKPTG 2535 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 53.9 bits (128), Expect = 6e-07 Identities = 46/127 (36%), Positives = 58/127 (45%), Gaps = 21/127 (16%) Query: 506 PEECGEPQPCPPAEPGP---PEAFCRSEPE-IPEPSLQEQLEVPEPYPPAEPRPLESCCR 561 PE EP P P EP P PE S PE PEP+L+ VPEP P P Sbjct: 95 PEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALE---SVPEPAPELTP-------E 144 Query: 562 SEPEI-PESSRQEQLEV-PEPCPPAEP--RPLESYCRIEPEIPESSRQEQLEVPEPCPPA 617 PE+ PE + + E+ PE CP A P RP + C + + P +R+ L+ P P Sbjct: 145 VAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLL--QCPVDTRERGLKT-SPSPSP 201 Query: 618 EPGPLQP 624 P P P Sbjct: 202 SPSPRTP 208 Score = 50.1 bits (118), Expect = 8e-06 Identities = 54/174 (31%), Positives = 65/174 (37%), Gaps = 20/174 (11%) Query: 502 KPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPL-ESCC 560 +P E P P PP P PP A PEP +PEP P P P E+ Sbjct: 19 QPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEP-------IPEPCPELAPGPCPEATS 71 Query: 561 RSEPEI-----PESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLE-VPEPC 614 S E+ PE + + E P P P EP P + PE + + E PEP Sbjct: 72 ESATELYTEPTPEPATEPASE-PAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPA 130 Query: 615 PPAEPGP---LQPSTQGQSGP-PGPCPRVELGASEPCTLEHRSLESSLPPCCSQ 664 + P P L P + P P P P EL A E C S PC Q Sbjct: 131 LESVPEPAPELTPEVAPELAPEPTPEPVTEL-APEFCPEAAPEFRPSPAPCLLQ 183 Score = 47.0 bits (110), Expect = 7e-05 Identities = 46/155 (29%), Positives = 56/155 (36%), Gaps = 20/155 (12%) Query: 540 EQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPL-----ESYCR 594 E E P P+PP P P P P S +PEPCP P P ES Sbjct: 22 ESPEPPPPWPPPPPPPAPP-----PAPPLLSEASPEPIPEPCPELAPGPCPEATSESATE 76 Query: 595 IEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSL 654 + E E P P P EP P +P+T+ + P P P E S P +L Sbjct: 77 LYTEPTPEPATEPASEPAPEPATEPAP-EPATE-PAPEPAPEPATE---SAPEPTPEPAL 131 Query: 655 ESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSL 689 ES P AP T + P P+ L Sbjct: 132 ESVPEP-----APELTPEVAPELAPEPTPEPVTEL 161 Score = 39.7 bits (91), Expect = 0.011 Identities = 29/84 (34%), Positives = 34/84 (40%), Gaps = 7/84 (8%) Query: 567 PESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPST 626 P ++ E PEP PP P P P P S +PEPCP PGP +T Sbjct: 13 PPQDGEQPAESPEPPPPWPPPPPPP--APPPAPPLLSEASPEPIPEPCPELAPGPCPEAT 70 Query: 627 QGQS----GPPGPCPRVELGASEP 646 + P P P E ASEP Sbjct: 71 SESATELYTEPTPEPATE-PASEP 93 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 53.9 bits (128), Expect = 6e-07 Identities = 103/384 (26%), Positives = 131/384 (34%), Gaps = 72/384 (18%) Query: 316 PGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGV 375 P V +P G Q P P + LTVQP + P STP G+ Sbjct: 590 PSAVAMLNTPDGLVQ----PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL------GL 639 Query: 376 SPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRI 435 + P P Q A Q + + G P G + TP+ I Sbjct: 640 QQPQAQQPPQAPTPQAAAP--PQATTPQPSPGLASSPEKIVLGQPPSATPTA----ILTQ 693 Query: 436 GILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLL 495 LQ L QE PL+ E L S ++A + + Sbjct: 694 DSLQMFLPQERSQQ------PLSA-------EGPHLSVPASVIVSAPPPAQDPAPATPVA 740 Query: 496 KHSGLPKPCLPEECGEPQPCP--PAE-----PGPPEAFCRSEPEIPEPS-LQEQLEVPEP 547 K +GL P P+ P P P PA PGP S P +P + L + +P P Sbjct: 741 KGAGLG-PQAPDSQASPAPAPQIPAAAPLKGPGPS-----SSPSLPHQAPLGDSPHLPSP 794 Query: 548 YPPAEP-RPLESCCRSEPEIPESSRQEQLEVP-EPCPPAEPRPLESYCRIEPEIPESSRQ 605 +P P RP P P+S + E P PCPP + P + Q Sbjct: 795 HPTRPPSRP--------PSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI--------Q 838 Query: 606 EQLEVPEPCP---PAEPGPLQPSTQGQSGPP-GPCPRV-ELGASEPCTLEHRSLESSLPP 660 QL VP P P PGP QP + QS PP GP P L S + S E+ Sbjct: 839 NQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSET---- 894 Query: 661 CCSQWAPATTSLIFSSQHPLCASP 684 S PA T F Q P P Sbjct: 895 --SSRLPAPTPSDFQLQFPPSQGP 916 Score = 45.8 bits (107), Expect = 2e-04 Identities = 48/201 (23%), Positives = 73/201 (36%), Gaps = 23/201 (11%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSL--QEQLEVPEPYPPAEPRPLES 558 P+ P + PQP P P + P ++ Q+ L++ P ++ +PL + Sbjct: 653 PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ-QPLSA 711 Query: 559 CCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCR---IEPEIPES--SRQEQLEVPEP 613 E P S + V P P +P P + + P+ P+S S ++P Sbjct: 712 ------EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAA 765 Query: 614 CPPAEPGPLQPSTQGQSGPPGPCPRV---------ELGASEPCTLEHRSLESSLPPCCSQ 664 P PGP + P G P + S P ++ E L PC Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPP 825 Query: 665 WAPATTSLIFSSQHPLCASPP 685 AP T IF Q+ L PP Sbjct: 826 QAPPTLPGIFVIQNQLGVPPP 846 Score = 44.3 bits (103), Expect = 4e-04 Identities = 55/224 (24%), Positives = 82/224 (36%), Gaps = 35/224 (15%) Query: 499 GLPKPCLPEEC-GEPQPCPPAEPGPPEAFCRSEP---EIPEPSLQEQLEVPEPYPPAEPR 554 GL +P P GE P +P P S P + +P Q+ + P P A P+ Sbjct: 601 GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ 660 Query: 555 PLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLE----- 609 +P +S E++ + +P P A P + + ++ +P+ Q+ L Sbjct: 661 ----ATTPQPSPGLASSPEKIVLGQP-PSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715 Query: 610 --------VPEPCPPAEPGPLQPSTQGQS-GP------PGPCPRVELGASEPCTLEHRSL 654 V P P +P P P +G GP P P ++ A+ P S Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS 775 Query: 655 ESSLPPCCSQWAPATTSLIFSSQHPL--CASPPICSLQSLRPPA 696 SLP AP S S HP + PP RPP+ Sbjct: 776 SPSLP----HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815 Score = 40.4 bits (93), Expect = 0.006 Identities = 93/419 (22%), Positives = 136/419 (32%), Gaps = 81/419 (19%) Query: 68 PRPKARHQAETSQRLVGISQPRNPLEELRPSPRG----QNVGPGP-PAQTEAPGTIEFVA 122 P P+A T L G+ QP+ P+P+ Q P P P +P I Sbjct: 623 PAPQAPPAVSTPLPL-GLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQ 681 Query: 123 DPAALATILSGEGVKSCHLGRQ----------PSLAKRVLVRGSQGGTTQR---VQGVRA 169 P+A T + + L ++ P L+ V S Q V Sbjct: 682 PPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAK 741 Query: 170 SAYLAPRTPTHRLDPARAS---CFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPS 226 A L P+ P + PA A + L+GPGP P + SP PS HP+ PS Sbjct: 742 GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801 Query: 227 FQELRRETAGSSRT-----------SVSQASGLLL----------------------ETP 253 R ++ + + G+ + + P Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861 Query: 254 VQPAFSLPKGEREVVTH----SDEGGVASLG-LAQRVPLRENREMS-HTRDSHDSHLMPS 307 ++P P+G H S VAS + R+P + S H P+ Sbjct: 862 LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT 921 Query: 308 PAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQ 367 P P +P P P P Q V +P P ++L RF +PS +Q Sbjct: 922 PPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLE--------RFHQVPSGIILQ 973 Query: 368 QAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPS 426 PA P Q + L S S+ SG+ P TP+ P P+ Sbjct: 974 ----------NKAGGAPAAP--QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020 Score = 32.3 bits (72), Expect = 1.7 Identities = 57/230 (24%), Positives = 77/230 (33%), Gaps = 26/230 (11%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPR-PLESC 559 P P + EP P PP P PP + P P+ E+ P P PR PL Sbjct: 1334 PPPPATLKVAEPPPRPPPPP-PPTGQMNGTVDHPPPAAPER--KPLGTAPHCPRLPLRKT 1390 Query: 560 CRSE---PEIPESSRQEQLE--VPEPCPPAEPRPLESYCRIEPEIPESSRQEQLE--VPE 612 R P PE + + P P P R + + Q L+ PE Sbjct: 1391 YRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE 1450 Query: 613 PCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRS---------LESSLPPCCS 663 P A G P + PP + E + + S L+S++ + Sbjct: 1451 PAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILN 1510 Query: 664 -QWAPATT---SLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTL 709 Q AP T S ++ ASPP PP+ G L RTL Sbjct: 1511 LQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNG--GLGARTL 1558 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 53.9 bits (128), Expect = 6e-07 Identities = 107/433 (24%), Positives = 156/433 (36%), Gaps = 68/433 (15%) Query: 196 PGPRGRTLCPQRLQALISPS--GPSFHPSTRPSFQELRRETAGSSRTSVSQASGLLLET- 252 P PRGR R++ L P+ GP+ + ++ R G R + +A G LE Sbjct: 1168 PRPRGRP----RIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKA-EEAGGTRLEPL 1222 Query: 253 -PVQPAFSLPKGER-------EVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHL 304 P++ S+PK + ++ +D + S +++ + +E+ + S Sbjct: 1223 KPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKI-KEVEEKQPEMKSGF 1281 Query: 305 MPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 M S + H P +A P PP SV R +QP+ TP P Sbjct: 1282 MASFLDFLKSGKRH-----PPLYQAGLTPPLSPPKSVPPSVPAR-GLQPQPPATPAVPHP 1335 Query: 365 RVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRT 424 A L G + SE L RL E R+LE PS Sbjct: 1336 PPSGAFGLGGALEAAESEGLGLGCPSPCKRL--DEELKRNLE-------TLPS------F 1380 Query: 425 PSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEH 484 S +E + + LQ+ + + L PL G + PL + Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISAL---DDPPLAGPKDTSTPDGPPLAPAAAVP------ 1431 Query: 485 NSGTSHLPGL--LKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQL 542 G LPGL +G P+P L EE +P P PP P P +P+ P P Q Sbjct: 1432 --GPPPLPGLPSANSNGTPEPPLLEE--KPPPTPPPAPTP-------QPQPPPPPPPPQP 1480 Query: 543 EVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPES 602 +P P P P P S P P +P P PP P P + PE P + Sbjct: 1481 ALPSPPPLVAPTP------SSPPPPPLPPPPPPAMPSPPPP--PPPAAAPLAAPPEEPAA 1532 Query: 603 SRQEQLEVPEPCP 615 E E+P+ P Sbjct: 1533 PSPEDPELPDTRP 1545 Score = 45.1 bits (105), Expect = 3e-04 Identities = 85/370 (22%), Positives = 129/370 (34%), Gaps = 61/370 (16%) Query: 305 MPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTP 364 +PSP P+ P P P P P +PSP PP + + L P+ P P P Sbjct: 1482 LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL---AAPPEEPAAPSPEDP 1538 Query: 365 RVQQAQWLRGVSPQS----CSEDPALPWEQVAVRLF-DQESCIRSLEGSGKPPVATPSGP 419 + + L Q C E E +F +++ + E +A +G Sbjct: 1539 ELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTG- 1597 Query: 420 HSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQ---CVPLN--GGSSLDMVELQPLLTE 474 P + V+ + LL++ + GQ C N G Q L + Sbjct: 1598 --REPPPIWRVQ-------KALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVK 1648 Query: 475 ISRTLNATEHNSGTS----HLPGL-LKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRS 529 +N ++ + H P + ++ SG K P G PP P PP Sbjct: 1649 FLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKN--PVSAGGSSAPPPKAPAPP-----P 1701 Query: 530 EPEIPEPSLQE-------QLEVPEPYPPAEP---RPLESCCRSEP----------EIPES 569 +PE PE + E + +PEP P +P RP+E E E S Sbjct: 1702 KPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATS 1761 Query: 570 SRQ----EQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPS 625 RQ L +P P+ + + EP P R++ L+ A GP S Sbjct: 1762 GRQTRPERSLATGQPATSRLPKARPTKVKAEP--PPKKRKKWLKEAGGNATAGGGPPGSS 1819 Query: 626 TQGQSGPPGP 635 + +S P P Sbjct: 1820 SDSESSPGAP 1829 Score = 44.7 bits (104), Expect = 3e-04 Identities = 54/189 (28%), Positives = 68/189 (35%), Gaps = 42/189 (22%) Query: 491 LPGLLKHSGLPKPCLPE----------ECGEPQPCPPAEPGPP------EAFCRS---EP 531 LP +L H+ P P + G PQP PP P PP EA RS EP Sbjct: 802 LPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEP 861 Query: 532 EIPEP------------SLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPE 579 P P ++QE L EP PPA SE + P + + P Sbjct: 862 AAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRS----PS 917 Query: 580 PCPPAEPR--PLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCP 637 P PR PL S C P+S Q++ P G G++GPP Sbjct: 918 PQGTKAPRFVPLTSIC-----FPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEG 972 Query: 638 RVELGASEP 646 + GA P Sbjct: 973 DPKAGAGPP 981 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/126 (30%), Positives = 43/126 (34%), Gaps = 36/126 (28%) Query: 514 PCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQE 573 P PP PG P A + PEP L E E P P PP P Sbjct: 1431 PGPPPLPGLPSA---NSNGTPEPPLLE--EKPPPTPPPAP-------------------- 1465 Query: 574 QLEVPEPCPPAEPRPLESYCRIEPEI--PESSRQEQLEVPEPCPPAEPGPLQPSTQGQSG 631 P+P PP P P + P + P S +P P PPA P P P Sbjct: 1466 ---TPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP------ 1516 Query: 632 PPGPCP 637 PP P Sbjct: 1517 PPAAAP 1522 Score = 33.9 bits (76), Expect = 0.59 Identities = 38/150 (25%), Positives = 52/150 (34%), Gaps = 19/150 (12%) Query: 493 GLLKHSGL-PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPY--- 548 G+L +GL P P G P P PP P + + + ++ P+ Y Sbjct: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSS--PQLYNFS 269 Query: 549 --PPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQE 606 P P P + R + I R + P P PPA L+ Y P + Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPA--HALQHYLSCGGSYPSMGHRA 327 Query: 607 QLEVPEPCPP-----AEPGPLQPSTQGQSG 631 L C P PG +PS G SG Sbjct: 328 NL----ACSPLGGGEPSPGAGEPSKAGPSG 353 Score = 33.1 bits (74), Expect = 1.0 Identities = 71/295 (24%), Positives = 99/295 (33%), Gaps = 65/295 (22%) Query: 306 PSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPR 365 PSP+P A + H++ + G Q P P PP PMP Sbjct: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP------------------PPMP---- 847 Query: 366 VQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSN--- 422 +Q LR + + P L E+ + + +LE P T GP ++ Sbjct: 848 LQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGK 907 Query: 423 ------RTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEIS 476 R+PS Q K R L + C P LL + Sbjct: 908 DPAGAYRSPSPQGTKAPRFVPLTSI------------CFP------------DSLLQDEE 943 Query: 477 RTLNAT-EHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPE 535 R+ T E G G G P PE+ G+P+ PGPP A+ P P Sbjct: 944 RSFFPTMEEMFG----GGAADDYGKAGP--PEDEGDPKAGAGPPPGPP-AYDPYGPYCPG 996 Query: 536 PSLQEQLEVPE-PYPPAEPRPLESCCRSEP-EIPESSRQEQLEVPEPCPPAEPRP 588 + E P P +P L S +EP + +S + P P PP P P Sbjct: 997 RASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAP 1051 Score = 32.0 bits (71), Expect = 2.3 Identities = 49/202 (24%), Positives = 65/202 (32%), Gaps = 20/202 (9%) Query: 499 GLPKPC--LPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPL 556 G P PC L EE P+ E ++ E S+ + + P A P+ Sbjct: 1358 GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQE-SISSAISALDDPPLAGPKDT 1416 Query: 557 ESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPP 616 S P+ P + + P PP P + PE P ++ P P P Sbjct: 1417 -----STPDGPPLAPAAAV----PGPPPLPGLPSANSNGTPE-PPLLEEKPPPTPPPAPT 1466 Query: 617 AEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQ----WAPATTSL 672 +P P P Q P P P V A P + L PP PA L Sbjct: 1467 PQPQPPPPPPPPQPALPSPPPLV---APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL 1523 Query: 673 IFSSQHPLCASPPICSLQSLRP 694 + P SP L RP Sbjct: 1524 AAPPEEPAAPSPEDPELPDTRP 1545 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 53.1 bits (126), Expect = 9e-07 Identities = 116/455 (25%), Positives = 148/455 (32%), Gaps = 113/455 (24%) Query: 307 SPAPVAQPLPGHV---VPCPSPFGRAQRVP-----SPGPPTLTSY--------------S 344 SP + LP V VP PFG A P PPT Y + Sbjct: 2155 SPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214 Query: 345 VLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRS 404 R QP T P TPR Q + + P+ S D E V Sbjct: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV----------- 2263 Query: 405 LEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLD 464 G GK S P + EVK + +G P G +L Sbjct: 2264 --GGGKASEPLLSPPPFGESRKALEVKKEELGASS----------------PSYGPPNLG 2305 Query: 465 MVELQPLLTEISRTLNATEHNSGTSHLPGL-LKHSGLPKPCLPEECGEPQPCPPA----- 518 V+ +SGT HL GL LK + K L + +P P Sbjct: 2306 FVD---------------SPSSGT-HLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRP 2349 Query: 519 -EPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPL----ESCC----RSEPEIPES 569 EP P +A S P P+ P PP PRP ESCC RS P P S Sbjct: 2350 QEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS 2409 Query: 570 ----SRQEQLEVPEPCPPAEPRPLESYC------RIEPEIPES---SRQEQLE------- 609 S Q Q P P P E++C R + P S SR + + Sbjct: 2410 RVPASPQSQSSSQSPLTP-RPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468 Query: 610 VPEPCPPA---EPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWA 666 P P PP + G L ++ G G P P + P H + S PP + + Sbjct: 2469 PPRPQPPEVAFKAGSLAHTSLGAGGFPAALP------AGPAGELHAKVPSGQPPNFVR-S 2521 Query: 667 PATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGL 701 P T + + + P SL+PP Q GL Sbjct: 2522 PGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556 Score = 51.2 bits (121), Expect = 4e-06 Identities = 67/226 (29%), Positives = 81/226 (35%), Gaps = 55/226 (24%) Query: 505 LPEECGEPQPCPPAE-----PGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESC 559 LPEE PQ CP +E P P E PE EP L Q E P P+P E C Sbjct: 728 LPEE---PQLCPRSEGPHLSPRPEEPHLSPRPE--EPHLSPQAEEPH----LSPQPEEPC 778 Query: 560 CRSEPEIPESSRQE----------------QLEVPEPCPPAE-----PRPLESYCRIEPE 598 + PE P S Q Q E P P E P+P ES+ + P+ Sbjct: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH--LSPQ 836 Query: 599 IPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSL 658 E + E P E PL P + PG CP A E L E SL Sbjct: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP-----APEELPLFPPPGEPSL 891 Query: 659 PPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRP--PAGQAGLS 702 P + PA + PP+ L P P+G+ LS Sbjct: 892 SPLLGE--PALSE---------PGEPPLSPLPEELPLSPSGEPSLS 926 Score = 46.2 bits (108), Expect = 1e-04 Identities = 64/240 (26%), Positives = 79/240 (32%), Gaps = 46/240 (19%) Query: 503 PCLPEECGEPQPCPPAEPG---PPEAFCRSEP--EIPEPSLQEQLEVPEPY------PPA 551 P LP P PP E PPEA S P E+P L E L + P PP Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498 Query: 552 EPRPLESCCRSEPEIP----------ESSRQEQLEVPEPCPPAEPRPLESYCRIEP---- 597 E PL S P P ES LE P PP E PL P Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPEASPLSPPFEESPLSPP 557 Query: 598 --EIPESSRQEQLEVPEP------CPPAEPGPLQPSTQG-------QSGPPGPCPRVELG 642 E+P S E + P PP E P+ P + + P P P Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE---- 613 Query: 643 ASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLS 702 P + + S PP S +P S + P+ + L PP ++ LS Sbjct: 614 -ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672 Score = 45.4 bits (106), Expect = 2e-04 Identities = 56/186 (30%), Positives = 67/186 (36%), Gaps = 22/186 (11%) Query: 516 PPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPE-------IPE 568 PP E P P P P +L P P P P +S PE + E Sbjct: 664 PPPEESPLSPPPEESPTSPPPEAS-RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722 Query: 569 SSRQEQLEVPEPCPPAE-----PRPLESYCRIEPEIPESSRQEQLEVPEPCP-PAEP--- 619 S E P+ CP +E PRP E + PE P S Q E P P P EP Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS--PQAEEPHLSPQPEEPCLC 780 Query: 620 -GPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQH 678 P +P Q+ P P+ E P T E PC S P + L S+ Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP-QPEESHLSPQSEE 839 Query: 679 PLCASP 684 P C SP Sbjct: 840 P-CLSP 844 Score = 45.1 bits (105), Expect = 3e-04 Identities = 128/537 (23%), Positives = 179/537 (33%), Gaps = 88/537 (16%) Query: 196 PGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASGLLLETPVQ 255 P P L P + +SP P P + P E+ S VS+ S L PV Sbjct: 610 PPPEESPLSPPPEASRLSPP-PEDSPMSPPP-----EESPMSPPPEVSRLSPL----PVV 659 Query: 256 PAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPL 315 S P E + +E + P E +S + + P +P + P Sbjct: 660 SRLSPPPEESPLSPPPEESPTS--------PPPEASRLSPPPEDSPTSPPPEDSPASPPP 711 Query: 316 PGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKT-RFTPMPSTPRVQQAQWLRG 374 ++ P + +P P P L S L+ +P+ +P P P + Sbjct: 712 EDSLMSLP--LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH 769 Query: 375 VSPQSCSEDP---ALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVK 431 +SPQ E+P A+P E L + P +P + +P +E Sbjct: 770 LSPQP--EEPCLCAVPEEP-------------HLSPQAEGPHLSPQPEELHLSPQTEEPH 814 Query: 432 IQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTE--ISRTLNATEHNSGTS 489 + + L Q E + Q + L P L + +S G Sbjct: 815 LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC 874 Query: 490 HLPGLLKHSGLP-KPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIP--EPSLQEQLEVPE 546 P L P +P L GEP P EP P P P EPSL QL P+ Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEP-PLSPLPEELPLSPSGEPSLSPQLMPPD 933 Query: 547 PYPP---------AEPR---------PLESCCRSEPEIPESSRQEQLEVPEPCPP----A 584 P PP A P P + S+PE P ++ LE P PP Sbjct: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA--PILETPISPPPEANCT 991 Query: 585 EPRPLESYCRIEPEIPESSRQEQLEV-PEPCPPAEPGPLQPSTQGQSGPPGPC--PRVEL 641 +P P+ I P P S + EP PP LQ S Q+ PP C P + L Sbjct: 992 DPEPVPPM--ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL 1049 Query: 642 -------------GASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPL-CASP 684 G S+ L E P C P+ TS + S L C +P Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP 1106 Score = 43.5 bits (101), Expect = 7e-04 Identities = 58/213 (27%), Positives = 70/213 (32%), Gaps = 11/213 (5%) Query: 490 HLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYP 549 HL L+ S L P P P P E P P+L+ L P Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543 Query: 550 PAEPRPLESCCRSEP--EIPESSRQE--QLEVPEPCPPAEPRPLESYCRIEPEIPESSRQ 605 P P P E S P E+P S E +L P P P P ES + P PE+SR Sbjct: 544 PLSP-PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES--PMSPP-PEASRL 599 Query: 606 -EQLEVPEPCPPAEPGPLQPSTQGQ--SGPPGPCPRVELGASEPCTLEHRSLESSLPPCC 662 E PP E PL P + S PP P P + S P Sbjct: 600 FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659 Query: 663 SQWAPATTSLIFSSQHPLCASPPICSLQSLRPP 695 S+ +P S + P L PP Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692 Score = 39.3 bits (90), Expect = 0.014 Identities = 148/735 (20%), Positives = 231/735 (31%), Gaps = 177/735 (24%) Query: 15 VSPTPSKIPVRSQKRTPFPTVTSCAVDQENQD----PRRWVQKPPLNIQR----PLVDSA 66 +SP P + P+ +P P + + E+ P PP + R P+V Sbjct: 608 LSPPPEESPL-----SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662 Query: 67 GPRPKARHQAETSQRLVGISQPRNPLEELRPS---PRGQNVGPGPPAQTEAPGTIEFVAD 123 P P+ P +P E P+ P + P P +P + A Sbjct: 663 SPPPE--------------ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708 Query: 124 PAALATILSGEGVKS--CHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHR 181 P +++S +S L +P L R S+G + +L+PR Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPR-----SEG---PHLSPRPEEPHLSPRPEEPH 760 Query: 182 LDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTS 241 L P P P LC + +SP H S +P L +T + Sbjct: 761 LSPQAEEPHL---SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817 Query: 242 VSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHD 301 V P +P S E + S+E ++ P E +S + Sbjct: 818 V----------PEEPCLSPQPEESHLSPQSEEPCLS--------PRPEESHLSPELEK-- 857 Query: 302 SHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMP 361 P +P + P CP+P P PG P+L+ L+ + +P+P Sbjct: 858 ----PPLSPRPEKPPEEPGQCPAP-EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP 912 Query: 362 STPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSG--- 418 + + +SPQ DP P + + + PP +P G Sbjct: 913 EELPLSPSGE-PSLSPQLMPPDPLPP-------------PLSPIITAAAPPALSPLGELE 958 Query: 419 -PHSNRTPSLQEVKIQRIGILQQLLRQEVEGL------VGGQCVPLNGGSSL---DMVEL 468 P + S E + IL+ + E V +P + GS + + + Sbjct: 959 YPFGAKGDSDPESPLAA-PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017 Query: 469 QPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCR 528 +PL + S LL+HS +P+ P +C PPA P Sbjct: 1018 EPLPPQCSP----------------LLQHSLVPQNSPPSQCS-----PPALP-------- 1048 Query: 529 SEPEIPEPSLQEQLEVPEPYPP----------AEPRPLESCCRSEPEIPESSRQEQLEVP 578 L VP P P AE +E+ SEPE P +P Sbjct: 1049 -------------LSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLP 1095 Query: 579 EP-----CPPAEPRP-LESYCRI-----------------EPEIPESSRQEQLE------ 609 P CP P P L+ + + EP S +L+ Sbjct: 1096 SPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLL 1155 Query: 610 VPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPAT 669 PE P P + P + +G PC E + ++S + S + Sbjct: 1156 DPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGD 1215 Query: 670 TSLIFSSQHPLCASP 684 S F PL SP Sbjct: 1216 ASASFPGSEPLLGSP 1230 Score = 38.5 bits (88), Expect = 0.024 Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 27/213 (12%) Query: 511 EPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYP-PAEPRPL-ESCCRSEPEIPE 568 EP P EP C+ +P+ + ++ EP P E +PL ++ + EP++ Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVT---SMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432 Query: 569 SSRQEQLEVPEP-----CPPAEPRPLE---SYCRIEP---EIPESSRQEQLEVPEP---- 613 +E +P P PP E P R+ P E+P S E L + P Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492 Query: 614 --CPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSL--PPCCSQWAPAT 669 PP E PL P +S P P L E + +LE+ L PP S +P Sbjct: 493 PLSPPPEESPLSPPP--ESSPFSPLEESPLSPPEE-SPPSPALETPLSPPPEASPLSPPF 549 Query: 670 TSLIFSSQHPLCASPPICSLQSLRPPAGQAGLS 702 S + P L PP ++ +S Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582 Score = 37.7 bits (86), Expect = 0.041 Identities = 37/137 (27%), Positives = 44/137 (32%), Gaps = 7/137 (5%) Query: 506 PEECGEPQPCP---PAEPGPPEAFCRSEPEIPE---PSLQEQLEVPEPYPPAEPRPLESC 559 P E P P P P P E+ PE P + L P P P P S Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625 Query: 560 CRSEPE-IPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAE 618 PE P S E+ + P + PL R+ P ES E PP E Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE 685 Query: 619 PGPLQPSTQGQSGPPGP 635 L P + P P Sbjct: 686 ASRLSPPPEDSPTSPPP 702 Score = 35.4 bits (80), Expect = 0.20 Identities = 34/123 (27%), Positives = 38/123 (30%), Gaps = 15/123 (12%) Query: 516 PPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQL 575 PP E P P P P +L P P P P ES PE+ S + Sbjct: 601 PPFEESPLSPPPEESPLSPPPEAS-RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659 Query: 576 EVPEPCP---PAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGP 632 P P P P P ES PE S PP E P P + Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLS-----------PPPEDSPTSPPPEDSPAS 708 Query: 633 PGP 635 P P Sbjct: 709 PPP 711 Score = 35.4 bits (80), Expect = 0.20 Identities = 88/341 (25%), Positives = 126/341 (36%), Gaps = 85/341 (24%) Query: 333 PSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQ-------------- 378 P P+L+ S L L VQP+ + P PS+ ++Q L G Q Sbjct: 4062 PGEVKPSLSGDSQL--LLVQPQPQ--PQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117 Query: 379 -----SCSEDPALPW--EQVAVRLFDQE-SCIRSLEGSGKP----PVATPSGPHSNRT-P 425 S SE ++P Q +V L DQ S ++L G +P P+ +GP + P Sbjct: 4118 QLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGP 4177 Query: 426 SLQEVK-IQRIGILQQL--LRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTE-------- 474 LQ + + +GI+ + LR +++G++ L S +LQ LL + Sbjct: 4178 VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN-PQLRHLSPQQQQQLQALLMQRQLQQSQA 4236 Query: 475 ISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIP 534 + +T E + TS L GLL C P+ G P P + GP Sbjct: 4237 VRQTPPYQEPGTQTSPLQGLLG-------CQPQLGGFPGP----QTGP------------ 4273 Query: 535 EPSLQEQLEVPEPY-PPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYC 593 LQE P P PP P P + P P P P EP+ Sbjct: 4274 ---LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP------TPPPSSPQEPKR----- 4319 Query: 594 RIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPG 634 ++P S QL PP PG +P PPG Sbjct: 4320 --PSQLPSPS--SQLPTEAQLPPTHPGTPKPQGPTLEPPPG 4356 Score = 33.1 bits (74), Expect = 1.0 Identities = 89/370 (24%), Positives = 126/370 (34%), Gaps = 78/370 (21%) Query: 53 KPPLNIQRPLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQT 112 +PP + P D G P H A SQR GI+ P E R P G +G A Sbjct: 2611 RPPSVLPPPAPD--GSLPYLSHGA--SQRS-GITSP----VEKREDP-GTGMGSSL-ATA 2659 Query: 113 EAPGTIEFVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAY 172 E PGT DP +SG RQ + +L+R T R + A+A Sbjct: 2660 ELPGT----QDPG-----MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAA 2710 Query: 173 LAPRTP--THRLDPARASCFSRLEGPGPRGRTLCPQRLQALISP--SGPSFHPSTRPSFQ 228 P + +P+ + G P T L L SGP P + PS Sbjct: 2711 AGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD 2770 Query: 229 ELRRETAGSSRTSVSQASGLLL--------ETPVQPAFSLPKGEREVVTHSDEGGVASLG 280 L R ++ +S+ S L+ P + L + ++++ S+ Sbjct: 2771 RLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMR 2830 Query: 281 LAQ--RVPLRENREMSHTRDSHDSHLMPSP-APVAQPLPGHVVPCPSPFGRAQRV----- 332 A R P E+ + SP A ++ LPG P P P G AQ + Sbjct: 2831 FAMSARFPSTPGPELGR-------QALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHN 2883 Query: 333 ------------PSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVS---- 376 P GPP + RF P+ P + LRG++ Sbjct: 2884 VQKGLGPGGTPFPGQGPP--------------QRPRFYPVSEDPHRLAPEGLRGLAVSGL 2929 Query: 377 -PQSCSEDPA 385 PQ S PA Sbjct: 2930 PPQKPSAPPA 2939 Score = 32.3 bits (72), Expect = 1.7 Identities = 28/116 (24%), Positives = 42/116 (36%), Gaps = 3/116 (2%) Query: 523 PEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCP 582 P+ + + +P +L+ QL++ P P S + QL P P Sbjct: 4854 PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAP---P 4910 Query: 583 PAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPR 638 P EP P S P P + +L P P PL ++ +S P P R Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966 Score = 31.6 bits (70), Expect = 2.9 Identities = 90/422 (21%), Positives = 145/422 (34%), Gaps = 47/422 (11%) Query: 243 SQASGLLLET-----PVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTR 297 S GLL++ P P L + V+ G + G ++V + ++R +S Sbjct: 3780 SSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSS-- 3837 Query: 298 DSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGP--------PTLTSYSVLRRL 349 P A Q L GH + + Q+ G +L S+S +L Sbjct: 3838 --------PQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL 3889 Query: 350 TVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSG 409 + QP + ++QQ Q L+ Q + L +Q+ + Q+ + + Sbjct: 3890 SAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ 3949 Query: 410 KPPVATPSGPHSNRTPSLQEVKIQRIGIL---------QQLLRQEVEGLVGGQCVPLNGG 460 + + Q+ + Q++G+L QQ +Q+V G PL Sbjct: 3950 QQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHF 4009 Query: 461 SSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKP--CLPEECG-EPQPCPP 517 SS L P L + N + + G H G P PE EP P Sbjct: 4010 SSPG--ALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKP 4067 Query: 518 AEPGPPEAFCRSEPEIPEPS---LQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQ 574 + G + P+PS LQ L +P + S ++ S E Sbjct: 4068 SLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEA 4127 Query: 575 LEVP----EPCPPAEPRP-LESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQ 629 VP +P +P + + P+ P R Q P PP +PGP+ S QG Sbjct: 4128 SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNT-GPQPP-KPGPVLQSGQGL 4185 Query: 630 SG 631 G Sbjct: 4186 PG 4187 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 52.8 bits (125), Expect = 1e-06 Identities = 104/450 (23%), Positives = 151/450 (33%), Gaps = 106/450 (23%) Query: 286 PLRENREMSHTRDSHDSHLMPSPAPVAQ---PLPGHVVPCPSPFGRAQRVPSPGPPTLTS 342 P RE ++ H H + +PAPV Q P P P P P + Q P P PP++ Sbjct: 731 PGREQKKHHH---HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM-- 785 Query: 343 YSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSE--DPALPWEQVAVRLFDQES 400 P+ M S+P A + + PQ DP + Q + L E Sbjct: 786 ----------PQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPEL 835 Query: 401 CIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGG 460 P P P + P L + + L L Q+ P N Sbjct: 836 -----------PPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSR-------PSNRA 877 Query: 461 SSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPE------ECGEPQP 514 ++L +P P L + LP+P + + E EP P Sbjct: 878 AALPPKPARPPAVS-----------------PALTQTPLLPQPPMAQPPQVLLEDEEP-P 919 Query: 515 CPPAEPGPPEAFCRS----EPEIPE-PSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPES 569 PP + + + +P P PS++ Q + P P PP P Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP---------------PHP 964 Query: 570 SRQEQLEV-PEPCPPAEPRPLESYCRIEPEIPESSRQEQL--EVPEPCPPAEPGPLQPST 626 S Q+QL+ P P PP +P+P P P + Q + +P PP P P Sbjct: 965 SVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024 Query: 627 QGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCA-SPP 685 Q PP P ++ H+S P +T + + PL SP Sbjct: 1025 GQQPPPPQPAKPQQVIQHHHSPRHHKS------------DPYSTGHLREAPSPLMIHSPQ 1072 Query: 686 ICSLQSL---RPPAGQAGLSNLAPRTLALR 712 + QSL PP N+ P+ LR Sbjct: 1073 MSQFQSLTHQSPPQ-----QNVQPKKQELR 1097 Score = 37.4 bits (85), Expect = 0.054 Identities = 45/191 (23%), Positives = 72/191 (37%), Gaps = 23/191 (12%) Query: 492 PGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPA 551 PG+ + P + PQP PP P F P + P L Q V P Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPF----PAV-TPDLIVQTPVMTVVP-- 243 Query: 552 EPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVP 611 P+PL+ + P +P P+P P P+P++S+ I P+ + ++ V Sbjct: 244 -PQPLQ----TPPPVPPQ--------PQPPPAPAPQPVQSHPPIIAATPQPVKTKK-GVK 289 Query: 612 EPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTS 671 P + P + S PP P +LG + + + +P AP +S Sbjct: 290 RKADTTTPTTIDPIHEPPSLPPEP-KTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSS 348 Query: 672 LIFSSQHPLCA 682 + S Q C+ Sbjct: 349 KV-SEQLKCCS 358 Score = 31.2 bits (69), Expect = 3.8 Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 16/126 (12%) Query: 3 TRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKP-PLNIQRP 61 T QA+ P + +P P+ PV++ PFP VT D Q P V P PL P Sbjct: 199 TTQASTPPQTQ--TPQPNPPPVQATPH-PFPAVTP---DLIVQTPVMTVVPPQPLQTPPP 252 Query: 62 LVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEFV 121 + P P Q Q P+ P P G A T P TI+ + Sbjct: 253 VPPQPQPPPAPAPQPV---------QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303 Query: 122 ADPAAL 127 +P +L Sbjct: 304 HEPPSL 309 >gi|236459851 ubinuclein 2 [Homo sapiens] Length = 1347 Score = 52.0 bits (123), Expect = 2e-06 Identities = 40/127 (31%), Positives = 53/127 (41%), Gaps = 15/127 (11%) Query: 528 RSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPR 587 R E E P P + + E P P EP+P R+EP P +E + PP+ + Sbjct: 17 RREAEYPGP--EREPEYPREPPRLEPQPYREPARAEPPAP----REPAPRSDAQPPSREK 70 Query: 588 PLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSG--------PPGPCPRV 639 PL + P S Q + PEP PP P PLQP +S PP R+ Sbjct: 71 PLPQR-EVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRETVRL 129 Query: 640 ELGASEP 646 EL +P Sbjct: 130 ELVLKDP 136 Score = 35.4 bits (80), Expect = 0.20 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPP---AEPRPLE 557 P P P + QP +P P R+EP + + E P P+PP P P E Sbjct: 52 PAPREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRE 111 Query: 558 SCCRSE--PEIPESSRQEQLEVPEP 580 S R+E P P + + +L + +P Sbjct: 112 SASRAEQPPRPPRETVRLELVLKDP 136 Score = 33.1 bits (74), Expect = 1.0 Identities = 32/118 (27%), Positives = 41/118 (34%), Gaps = 31/118 (26%) Query: 551 AEPR-----PLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQ 605 AEPR L R E E P R+ E P P EP+P R EP Sbjct: 2 AEPRRVAFISLSPVRRREAEYPGPEREP--EYPREPPRLEPQPYREPARAEP-------- 51 Query: 606 EQLEVPEPCPPAEPGPLQPSTQGQSGPPG---PCPRVELGASEPCTLEHRSLESSLPP 660 P P +P+ + + PP P P+ E+ +EP R PP Sbjct: 52 -------------PAPREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQREPPRPEPP 96 >gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] Length = 2303 Score = 52.0 bits (123), Expect = 2e-06 Identities = 103/416 (24%), Positives = 145/416 (34%), Gaps = 64/416 (15%) Query: 305 MPSPAPVAQP--LPGH-------VVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKT 355 +PSPAP AQP PG PC + +VPSPG S + + Sbjct: 1796 VPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATL 1855 Query: 356 RFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVA- 414 P +TP + A+ S Q+ LP ++ V +L G G PV Sbjct: 1856 SQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVT-----QAAGALPGPGASPVPK 1910 Query: 415 TPSGPHSNRTPSLQEVKIQR----IGILQQLLRQEV------------EGLVGGQCVPLN 458 TP+ RT ++ K QR I +Q+ R+ G G + P Sbjct: 1911 TPA-----RTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGA 1965 Query: 459 GGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPA 518 G L +V + L+ S + + SG +K S P L E A Sbjct: 1966 RGGRLGLVRVASALSSGSESSD----RSGFRRQLTFIKES----PGLRRRRSELSSAESA 2017 Query: 519 EPGPPEAFCR-SEPEIPE----PSLQEQLEVPEPYPPAEPRPLESCCRSEP-EIP--ESS 570 P A R P +P S E+L PA R R P E P ++ Sbjct: 2018 ASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTT 2077 Query: 571 RQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 + +P P A P ++ Y + P I + R P+ PA P + + Sbjct: 2078 SESPSRLPVRAPAARPETVKRYASL-PHISVARR------PDGAVPAAPASADAARRSSD 2130 Query: 631 GPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATT-SLIFSSQHPLCASPP 685 G P P PRV + P T R + +P PAT L S+ A PP Sbjct: 2131 GEPRPLPRV----AAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTPEDAPAGPP 2182 Score = 31.6 bits (70), Expect = 2.9 Identities = 43/193 (22%), Positives = 64/193 (33%), Gaps = 22/193 (11%) Query: 411 PPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQ- 469 PP P GP + P+ + + Q + + G+ + G+ + L+ Sbjct: 1414 PPRDQPGGPAGRQRPTGRPTSAR------QAMGHRHKAGGAGRSAEQSRGAGKNRAGLEL 1467 Query: 470 PLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKP------CLPEECGEPQPCPPAEPGP- 522 PL S + G + G L+ L P C + +P P A P P Sbjct: 1468 PLGRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEP-PAAAPTPT 1526 Query: 523 -------PEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQL 575 P AF R P+ + + P PPA +P + P SS L Sbjct: 1527 HRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSL 1586 Query: 576 EVPEPCPPAEPRP 588 PEP P P Sbjct: 1587 SEPEPSEPPAVHP 1599 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 50.8 bits (120), Expect = 5e-06 Identities = 75/271 (27%), Positives = 93/271 (34%), Gaps = 49/271 (18%) Query: 469 QPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCR 528 QPL T + A + H + +G P P + PQP P +P P +AF Sbjct: 916 QPLPTPYTYPAGAKQPIPAQHHFSSGIP-AGFPAPRIG-----PQPQPHPQPHPSQAFGP 969 Query: 529 SEPEIPEPSLQEQLEVPE---------PYPPA--------EPRPLESCCRSEP-EIPESS 570 P+ P P L P+ PYP A P PL + P + P + Sbjct: 970 QPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029 Query: 571 RQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQS 630 L P P PP P P +Y P P+ P G PS+ GQS Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGPAPSTRPMG--------PQAAPLTIRG---PSSAGQS 1078 Query: 631 GP-----PGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFS--SQHPLCAS 683 P P P P G P R + PPC + A A L S SQH S Sbjct: 1079 TPSPHLVPSPAPSPGPGPVPP-----RPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQS 1133 Query: 684 PPICSLQSLRPPAGQAGLSNLAPRTLALRER 714 P Q L P P+ L L ER Sbjct: 1134 PG--GGQPLLQPTKVDAAEGRRPQALRLIER 1162 Score = 44.3 bits (103), Expect = 4e-04 Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 21/139 (15%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESC 559 +P P P P PP P PP P+P L P YP +P+ + Sbjct: 891 IPSHTAPRPNPTPAPPPPCFPVPP----------PQP-----LPTPYTYPAGAKQPIPAQ 935 Query: 560 CRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQL---EVPEPCPP 616 IP ++ P+P P +P P +++ P+ P + L + P PP Sbjct: 936 HHFSSGIPAGFPAPRIG-PQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP 994 Query: 617 AEPGPL--QPSTQGQSGPP 633 P P QP GQ PP Sbjct: 995 QSPYPYAPQPGVLGQPPPP 1013 Score = 33.9 bits (76), Expect = 0.59 Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 48/180 (26%) Query: 490 HLPGLLKHSGLPKPCLP-------EECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQL 542 H+ +L+ G+P PC P ++ PQ G + I + S++ Sbjct: 1452 HVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPG 1511 Query: 543 EVPEPYP----PAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPE 598 + P PAEP P +P +S E +P PP PL PE Sbjct: 1512 GLESPVASLPGPAEP----------PGLPPASLPESTPIPSSSPPPLSSPL-------PE 1554 Query: 599 IPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSL 658 P+ P+ PP P SGPP +EL AS T E SL+SSL Sbjct: 1555 APQ---------PKEEPPVPEAP-------SSGPPS--SSLELLAS--LTPEAFSLDSSL 1594 Score = 33.5 bits (75), Expect = 0.78 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 13/97 (13%) Query: 442 LRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEIS-RTLNATEHNSGTSHLPGLLKHSGL 500 L Q+ + LV G VP++ +Q + ++S R E S + LPG + GL Sbjct: 1480 LPQDSQDLVLGGDVPISS--------IQATIAKLSIRPPGGLE--SPVASLPGPAEPPGL 1529 Query: 501 PKPCLPEECGEPQPCPP--AEPGPPEAFCRSEPEIPE 535 P LPE P PP + P P + EP +PE Sbjct: 1530 PPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPE 1566 Score = 31.6 bits (70), Expect = 2.9 Identities = 45/195 (23%), Positives = 69/195 (35%), Gaps = 45/195 (23%) Query: 524 EAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPP 583 ++ C++ + L +L+ P P P+PL +P E +E + PP Sbjct: 694 QSTCQAREAARQQLLDRELKKKPPPRPTAPKPL---------LPRREESEAVEAGD--PP 742 Query: 584 AEPRPLESYCRIEPEIPESSRQEQLEV---PEPCPPAE-------PGPLQPSTQGQSGPP 633 E R L P +P++ + P P P + GPL P T Sbjct: 743 EELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYS----- 797 Query: 634 GPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLI-----FSSQHPLCAS----- 683 GP ++ A P + + P APA T + S QH + +S Sbjct: 798 GPTQLIQPRAPGPHAMPVAPGPALYP------APAYTPELGLVPRSSPQHGVVSSPYVGV 851 Query: 684 ---PPICSLQSLRPP 695 PP+ L S PP Sbjct: 852 GPAPPVAGLPSAPPP 866 Score = 30.4 bits (67), Expect = 6.6 Identities = 26/86 (30%), Positives = 28/86 (32%), Gaps = 19/86 (22%) Query: 303 HLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPS 362 H P P PLP H P PSPGPP P + P PS Sbjct: 1015 HTQLYPGPAQDPLPAHSGALP--------FPSPGPPQ----------PPHPPLAYGPAPS 1056 Query: 363 T-PRVQQAQWLRGVSPQSCSEDPALP 387 T P QA L P S + P Sbjct: 1057 TRPMGPQAAPLTIRGPSSAGQSTPSP 1082 >gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] Length = 1243 Score = 50.4 bits (119), Expect = 6e-06 Identities = 43/137 (31%), Positives = 53/137 (38%), Gaps = 15/137 (10%) Query: 514 PCP-----PAEPGPPEAFCRSEPEIPEPSLQEQLEVPEP-----YPPAEPRPLESCCRSE 563 PCP P+ P S + ++ + L P P PPA P PL S Sbjct: 908 PCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPP 967 Query: 564 PEIP---ESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQ--EQLEVPEPCPPAE 618 P P ES EV P RPL R+ P E Q + +V PAE Sbjct: 968 PVAPGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAE 1027 Query: 619 PGPLQPSTQGQSGPPGP 635 P PLQP++ SG P P Sbjct: 1028 PLPLQPTSPTLSGSPKP 1044 Score = 37.7 bits (86), Expect = 0.041 Identities = 54/216 (25%), Positives = 72/216 (33%), Gaps = 31/216 (14%) Query: 506 PEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPE----PYPPAEPRPLESCCR 561 P E E P EP P A P+ LQ + + + P Sbjct: 754 PMEAAEDTLSPQEEPAPLPALPVPLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSP 813 Query: 562 SEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGP 621 P P + P PP P P P P SS+ P P P + P P Sbjct: 814 GNPFSPGTPISPGPIFPITSPPCHPSP-------SPFSPISSQVSSN--PSPHPTSSPLP 864 Query: 622 LQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSL-----PPCCSQWAPATTSLIFSS 676 ST P CP L + P T + +L PPC P+T+S ++ Sbjct: 865 FSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPC-----PSTSSFPSTT 919 Query: 677 QHPLCASPPICSL------QSLRPPAGQAGLSNLAP 706 PL + SL QSL P+ GL + +P Sbjct: 920 AAPLLSLASAFSLAVMTVAQSLLSPS--PGLLSQSP 953 Score = 34.3 bits (77), Expect = 0.45 Identities = 39/125 (31%), Positives = 44/125 (35%), Gaps = 23/125 (18%) Query: 456 PLNGGSSLDMVELQPLLTEISRTLNA--TEHNSGTSHLPGLLKHSG-----------LPK 502 P SS PLL+ S A T S S PGLL S LP Sbjct: 908 PCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPP 967 Query: 503 PCLPEECGEPQPC----------PPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAE 552 P P P P PPA P P EA E +P L + +V PAE Sbjct: 968 PVAPGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAE 1027 Query: 553 PRPLE 557 P PL+ Sbjct: 1028 PLPLQ 1032 Score = 30.8 bits (68), Expect = 5.0 Identities = 16/31 (51%), Positives = 16/31 (51%), Gaps = 1/31 (3%) Query: 505 LPEECGEPQPCPPAEPGPPEAFCRSEPEIPE 535 LP E G P P PGPP F EPE PE Sbjct: 533 LPPEPGPPPATVPMAPGPPSVF-PPEPEEPE 562 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 50.1 bits (118), Expect = 8e-06 Identities = 47/157 (29%), Positives = 65/157 (41%), Gaps = 33/157 (21%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPE-PSLQEQLEVPEPYPPAEPRPL-- 556 +PK +PE+ A P PE PE+P+ P L+E+ VP P P P Sbjct: 10752 VPKEVVPEK-------KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVY 10804 Query: 557 ---ESCCRSEPEIPESSR------QEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQ 607 E E PE + +E+ EVP P P EP+ + IPE + Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKI---------IPE-KKVPV 10854 Query: 608 LEVPEPCPPAEPGP----LQPSTQGQSGPPGPCPRVE 640 ++ PE PP EP P +P + + PP P P E Sbjct: 10855 IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKE 10891 Score = 48.9 bits (115), Expect = 2e-05 Identities = 46/135 (34%), Positives = 65/135 (48%), Gaps = 22/135 (16%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK +PE+ P PPA+ PEA PE P+ + E+ +VP P PP +P E Sbjct: 10501 PKEVVPEK---KVPVPPAKK--PEAPPPKVPEAPKEVVPEK-KVPVP-PPKKP---EVPP 10550 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 PE+P+++ E+ +VPE PP P PE+PE+ ++ VPE PA P Sbjct: 10551 TKVPEVPKAAVPEK-KVPEAIPPKPESP-------PPEVPEAPKE---VVPEKKVPAAP- 10598 Query: 621 PLQPSTQGQSGPPGP 635 P +P P P Sbjct: 10599 PKKPEVTPVKVPEAP 10613 Score = 48.1 bits (113), Expect = 3e-05 Identities = 43/147 (29%), Positives = 63/147 (42%), Gaps = 15/147 (10%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK +PE+ P PP P PE PE+P+ ++ E+ +VPE PP P Sbjct: 10613 PKEVVPEK---KVPVPP--PKKPEVPPTKVPEVPKVAVPEK-KVPEAIPPKPESPPPEVF 10666 Query: 561 RSEPEIP-ESSRQEQLEVPEPC-------PPAEPRPLESYCRIEPEIPESSRQEQLEVPE 612 E+ E E +E PEP PP +P P + + + PE + EVP+ Sbjct: 10667 EEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPK 10726 Query: 613 PCPPAEPGPLQPSTQGQSGPPGPCPRV 639 P + PL + ++ PP P V Sbjct: 10727 EVVPEKKVPLVVPKKPEA-PPAKVPEV 10752 Score = 47.8 bits (112), Expect = 4e-05 Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 32/160 (20%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCC 560 PK +PE+ P PP P PE PE+P+ ++ E+ +VPE PP P Sbjct: 10529 PKEVVPEK---KVPVPP--PKKPEVPPTKVPEVPKAAVPEK-KVPEAIPPKPESP----- 10577 Query: 561 RSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPG 620 PE+PE+ ++ VPE PA P P+ PE + + E P+ P + Sbjct: 10578 --PPEVPEAPKEV---VPEKKVPAAP----------PKKPEVTPVKVPEAPKEVVPEKKV 10622 Query: 621 PLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPP 660 P+ P + + PP P V A + + + ++PP Sbjct: 10623 PVPPPKKPEV-PPTKVPEVPKVA-----VPEKKVPEAIPP 10656 Score = 45.1 bits (105), Expect = 3e-04 Identities = 42/122 (34%), Positives = 56/122 (45%), Gaps = 10/122 (8%) Query: 501 PKPCLPEECGEPQP---CPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLE 557 P P +PE E P P A P PE PE P+ + E+ +VP P PP +P E Sbjct: 10577 PPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK-KVPVP-PPKKP---E 10631 Query: 558 SCCRSEPEIPESSRQEQLEVPEPCPP-AEPRPLESYCRIEPEIPESSRQEQLEVPEPCPP 616 PE+P+ + E+ +VPE PP E P E + E E E +E PEP P Sbjct: 10632 VPPTKVPEVPKVAVPEK-KVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAP 10690 Query: 617 AE 618 + Sbjct: 10691 PQ 10692 Score = 44.7 bits (104), Expect = 3e-04 Identities = 47/180 (26%), Positives = 74/180 (41%), Gaps = 31/180 (17%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAF---------CRSEPEIPEPSLQEQLEVP----- 545 + KP L P P PP E + F +P++PE L+VP Sbjct: 10872 IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKK 10931 Query: 546 --EPYPPAEPRP-----LESCCRSEPEIPESSRQ-EQLE------VPEPCPPAEPRPLE- 590 + P +P P L+S R PE E + ++LE VPEP PP +E Sbjct: 10932 VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV 10991 Query: 591 -SYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTL 649 + + E +IPE ++ +++ P P EP P +P + ++ P P + P T+ Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP-KPEAEVKTIKPPPVEPEPTPIAAPVTV 11050 Score = 43.5 bits (101), Expect = 7e-04 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 21/150 (14%) Query: 500 LPKPCLPEECGEPQPCPPA-EPGPPEAFCRSEPEIPEPSLQEQLEVPEP-------YPPA 551 +PK +PE+ P+ PP E PPE F E E E +E PEP PP Sbjct: 10640 VPKVAVPEK-KVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPK 10698 Query: 552 EPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVP 611 +P P + + PE + EVP+ P + PL + P+ PE+ + EVP Sbjct: 10699 KPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPL-----VVPKKPEAPPAKVPEVP 10753 Query: 612 EPCPPAE--PGPLQPSTQGQSGPPGPCPRV 639 + P + P +P PP P V Sbjct: 10754 KEVVPEKKVAVPKKPEV-----PPAKVPEV 10778 Score = 41.2 bits (95), Expect = 0.004 Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 15/154 (9%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEP-SLQEQLEV---PEPYPPAEPRP 555 +PK +PEE +P P P PP + +P P +L ++ EV E P E P Sbjct: 10063 VPKKLIPEE-KKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLP 10121 Query: 556 LESCCRSEPEIPESSRQEQLEVPEPCPPAEPR--PLESYCRIEPE-IPESSRQEQLEVPE 612 E E E +E L E PP E P E Y E E +PE +++ Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181 Query: 613 PCPPAEPGPLQPSTQ-------GQSGPPGPCPRV 639 P P P + T+ + PP P V Sbjct: 10182 PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEV 10215 Score = 40.0 bits (92), Expect = 0.008 Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 19/134 (14%) Query: 528 RSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPR 587 R EP P L E+ E P P+ +E PE+P+ E+ + P P P EP Sbjct: 9281 RVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEE-KKPVPVPKKEP- 9338 Query: 588 PLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELG--ASE 645 P++P EVP+ P E P+ P + + PP P V+ G E Sbjct: 9339 ------AAPPKVP--------EVPKKPVPEEKIPV-PVAKKKEAPPAKVPEVQKGVVTEE 9383 Query: 646 PCTLEHRSLESSLP 659 T+ + ES P Sbjct: 9384 KITIVTQREESPPP 9397 Score = 38.5 bits (88), Expect = 0.024 Identities = 44/173 (25%), Positives = 69/173 (39%), Gaps = 26/173 (15%) Query: 505 LPEECGEPQPCPPAEPGPPEAFCRSEPE-IPE----PSLQEQLEVPEPYPPAE------- 552 LPEE E P E P E + E E +PE P ++ ++ VP P P + Sbjct: 10141 LPEE--EEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKK 10198 Query: 553 ---PRPLESCCRSEPEIPESSRQEQLEVP---EPCPPAEPRPLESYCRIEPEIPESSRQE 606 P+ E+ PE+P+ ++++ +P E P E E EIPE Sbjct: 10199 VVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258 Query: 607 QLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLP 659 + EV E PP P ++ + P P P + + P + + E +P Sbjct: 10259 E-EVEEVAPPRVPEVIKKAV-----PEAPTPVPKKVEAPPAKVSKKIPEEKVP 10305 Score = 37.0 bits (84), Expect = 0.070 Identities = 37/147 (25%), Positives = 60/147 (40%), Gaps = 26/147 (17%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESC 559 +P+ +PEE +P P P + PP ++PE + + +VP P E P Sbjct: 9953 VPRKPVPEE-KKPVPVPKKKEAPPA-------KVPEVPKKPEEKVPVLIPKKEKPPPAKV 10004 Query: 560 CRSEPEIPESSRQEQLEVPEPCP-------------PAEPRPLESYCRIEPEIPESSRQE 606 PE+P+ E+ +VP P P P +P P + P+ E+ + Sbjct: 10005 ----PEVPKKPVPEE-KVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAK 10059 Query: 607 QLEVPEPCPPAEPGPLQPSTQGQSGPP 633 EVP+ P E P + ++ PP Sbjct: 10060 VPEVPKKLIPEEKKPTPVPKKVEAPPP 10086 Score = 35.8 bits (81), Expect = 0.16 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 25/153 (16%) Query: 506 PEECGEPQ-PCPPAEPGPPE---AFCRSEPEIPE---PSLQEQLEVPEPYPPAEPRPLES 558 PE PQ PP +P P + A +PE+P P + +++ + P P+ E+ Sbjct: 10685 PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744 Query: 559 CCRSEPEIP-ESSRQEQLEVPEP--CPPAEPRPLESYCRIE-------PEIPESSRQEQL 608 PE+P E ++++ VP+ PPA+ + +E PE ES E Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVY 10804 Query: 609 EVPEPCPPAE--------PGPLQPSTQGQSGPP 633 E PE P E P P+ + + PP Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPP 10837 Score = 35.4 bits (80), Expect = 0.20 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 26/154 (16%) Query: 501 PKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPL---E 557 P P +PE P +P P E P+ EP + EVP+ P E +P+ + Sbjct: 9284 PPPKVPEL--------PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPK 9335 Query: 558 SCCRSEPEIPESSR----QEQLEVP----EPCPPAEPRPLESYCRIEPEIPESSRQEQL- 608 + P++PE + +E++ VP + PPA+ ++ E +I +++E+ Sbjct: 9336 KEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESP 9395 Query: 609 -----EVPEPCPPAEPGPLQPSTQGQSGPPGPCP 637 E+P+ P E P+ P + + PP P Sbjct: 9396 PPAVPEIPKKKVPEERKPV-PRKEEEVPPPPKVP 9428 Score = 35.4 bits (80), Expect = 0.20 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 13/123 (10%) Query: 500 LPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPE--IPEPSLQEQLEVPEPYPPAEPRPLE 557 +P +PEE P P P P P + ++ PE +P P + ++L+ P P P EP+ + Sbjct: 9793 IPVKPVPEE---PVPTKPKAP-PAKVLKKAVPEEKVPVP-IPKKLKPPPPKVPEEPKKV- 9846 Query: 558 SCCRSEPEIPES-SRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPP 616 E +I S +++E+ +V EP +P + +P + VPE Sbjct: 9847 ----FEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902 Query: 617 AEP 619 EP Sbjct: 9903 LEP 9905 Score = 35.4 bits (80), Expect = 0.20 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 7/124 (5%) Query: 512 PQPCPPAEPG--PPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPES 569 P+ PPA+ P + + +PE +VPE PP E P + + PE+ Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEA 10520 Query: 570 SRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQ 629 + E P+ P + P+ P+ PE + EVP+ P + P + + Sbjct: 10521 PPPKVPEAPKEVVPEKKVPVPP-----PKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE 10575 Query: 630 SGPP 633 S PP Sbjct: 10576 SPPP 10579 Score = 34.3 bits (77), Expect = 0.45 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 24/132 (18%) Query: 503 PCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYP------------- 549 P PEE P P E PP PE+P+ + E+ +VP P P Sbjct: 9982 PKKPEE-KVPVLIPKKEKPPPAKV----PEVPKKPVPEE-KVPVPVPKKVEAPPAKVPEV 10035 Query: 550 PAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIE---PEIPESSRQE 606 P +P P + P+ E+ + EVP+ P E +P ++E P++P+ ++E Sbjct: 10036 PKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPK--KRE 10093 Query: 607 QLEVPEPCPPAE 618 + VP P E Sbjct: 10094 PVPVPVALPQEE 10105 Score = 33.9 bits (76), Expect = 0.59 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 20/120 (16%) Query: 502 KPCLPEECGEPQPC-----PPAEPGPPEAFCRSEPEIPEPSLQE--------QLEVPEPY 548 +P EE E P A P PE ++ PE P P ++ ++PE Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303 Query: 549 PPAEPRPLESCCRSEPEIPESSRQEQLEVP--EPCPPAEPRPLESYCRIEPEIPESSRQE 606 P + E+ PE+P+ ++++ VP E PPA+ R + +E ++ + RQE Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTV-----LEEKVSVAFRQE 10358 Score = 30.8 bits (68), Expect = 5.0 Identities = 29/114 (25%), Positives = 44/114 (38%), Gaps = 16/114 (14%) Query: 507 EECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEI 566 EE + P P E + P +PE + E P P P P + PE Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE- 10301 Query: 567 PESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVP--EPCPPAE 618 E++ VP A P + PE+P+ ++++ VP E PPA+ Sbjct: 10302 ------EKVPVPVQKKEAPPAKV-------PEVPKKVPEKKVLVPKKEAVPPAK 10342 Score = 30.0 bits (66), Expect = 8.6 Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 29/113 (25%) Query: 511 EPQPCPPAEPGPPEAFCRSEPEIPE--PSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPE 568 E + P PE SE EIPE PS++E EV + P +PE Sbjct: 10229 EEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV-----------------APPRVPE 10271 Query: 569 SSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVP---EPCPPAE 618 ++ E P P P P ++ +IPE E++ VP + PPA+ Sbjct: 10272 VIKKAVPEAPTPVPKKVEAP---PAKVSKKIPE----EKVPVPVQKKEAPPAK 10317 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 48.9 bits (115), Expect = 2e-05 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 53/279 (18%) Query: 474 EISRTLNATEHNSGTSHL------PGLLKHSGL----------PKPCLPEECGEPQPCPP 517 E+ +A H SG S L PG L S PKP LP P P PP Sbjct: 339 EVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLP-----PPPVPP 393 Query: 518 A-------------EPGPPEAFCRSEPEIPEPSLQEQ-LEVPE-PYPPAEPRPLESCCRS 562 EP PP F P P LQE+ L P P+P P P S + Sbjct: 394 PLLHYPPPAKVPGLEPCPPPPFPPMAP--PTALLQEEPLFSPRFPFPTVPPAPGVSPLPA 451 Query: 563 EPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCP---PAEP 619 P + + VP P P P L EP + + P P P A P Sbjct: 452 PAAFPPTPQS----VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASP 507 Query: 620 GPLQPSTQGQ---SGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSS 676 L P+T +G PC L A++P ++LE L +P + Sbjct: 508 PTLAPATASPPTTAGSNNPCLTQLLTAAKP----EQALEPPLVSSTLLRSPGSPQETVP- 562 Query: 677 QHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERL 715 + P PP + RPP G A L+ P + ERL Sbjct: 563 EFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERL 601 Score = 38.5 bits (88), Expect = 0.024 Identities = 66/282 (23%), Positives = 92/282 (32%), Gaps = 63/282 (22%) Query: 468 LQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFC 527 +QP LT + +L+ + +S LP+P +P EP P P F Sbjct: 282 IQPDLTPLQPSLD------DFMDISDFFTNSRLPQPPMPSNFPEP---PSFSPVVDSLFS 332 Query: 528 RSE--PEIPEPS-----------LQEQLEVPEPYP-----------PAEPRPLESCCRSE 563 PE+P S LQ + P P P +P+P Sbjct: 333 SGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVP 392 Query: 564 PEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGP-- 621 P + ++ EPCPP P+ + E P S + P P P P Sbjct: 393 PPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAP 452 Query: 622 --LQPSTQGQSGP---PGPCPRVELGASEPCTLEHRSLESSLPPCCS---------QWAP 667 P+ Q P P P + LG SEP S+ PP S AP Sbjct: 453 AAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAP 512 Query: 668 AT--------------TSLIFSSQHPLCASPPICSLQSLRPP 695 AT T L+ +++ PP+ S LR P Sbjct: 513 ATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP 554 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 48.9 bits (115), Expect = 2e-05 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 53/279 (18%) Query: 474 EISRTLNATEHNSGTSHL------PGLLKHSGL----------PKPCLPEECGEPQPCPP 517 E+ +A H SG S L PG L S PKP LP P P PP Sbjct: 339 EVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLP-----PPPVPP 393 Query: 518 A-------------EPGPPEAFCRSEPEIPEPSLQEQ-LEVPE-PYPPAEPRPLESCCRS 562 EP PP F P P LQE+ L P P+P P P S + Sbjct: 394 PLLHYPPPAKVPGLEPCPPPPFPPMAP--PTALLQEEPLFSPRFPFPTVPPAPGVSPLPA 451 Query: 563 EPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCP---PAEP 619 P + + VP P P P L EP + + P P P A P Sbjct: 452 PAAFPPTPQS----VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASP 507 Query: 620 GPLQPSTQGQ---SGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSS 676 L P+T +G PC L A++P ++LE L +P + Sbjct: 508 PTLAPATASPPTTAGSNNPCLTQLLTAAKP----EQALEPPLVSSTLLRSPGSPQETVP- 562 Query: 677 QHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERL 715 + P PP + RPP G A L+ P + ERL Sbjct: 563 EFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERL 601 Score = 38.5 bits (88), Expect = 0.024 Identities = 66/282 (23%), Positives = 92/282 (32%), Gaps = 63/282 (22%) Query: 468 LQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFC 527 +QP LT + +L+ + +S LP+P +P EP P P F Sbjct: 282 IQPDLTPLQPSLD------DFMDISDFFTNSRLPQPPMPSNFPEP---PSFSPVVDSLFS 332 Query: 528 RSE--PEIPEPS-----------LQEQLEVPEPYP-----------PAEPRPLESCCRSE 563 PE+P S LQ + P P P +P+P Sbjct: 333 SGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVP 392 Query: 564 PEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGP-- 621 P + ++ EPCPP P+ + E P S + P P P P Sbjct: 393 PPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAP 452 Query: 622 --LQPSTQGQSGP---PGPCPRVELGASEPCTLEHRSLESSLPPCCS---------QWAP 667 P+ Q P P P + LG SEP S+ PP S AP Sbjct: 453 AAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAP 512 Query: 668 AT--------------TSLIFSSQHPLCASPPICSLQSLRPP 695 AT T L+ +++ PP+ S LR P Sbjct: 513 ATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP 554 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,960,377 Number of Sequences: 37866 Number of extensions: 3107599 Number of successful extensions: 21869 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 123 Number of HSP's successfully gapped in prelim test: 1163 Number of HSP's that attempted gapping in prelim test: 13564 Number of HSP's gapped (non-prelim): 7184 length of query: 778 length of database: 18,247,518 effective HSP length: 110 effective length of query: 668 effective length of database: 14,082,258 effective search space: 9406948344 effective search space used: 9406948344 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.