Search of human proteins with 15451779

Search of human proteins with 15451779

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
sapiens]
         (585 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi...  1187   0.0  
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]   1164   0.0  
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]  1134   0.0  
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi...  1065   0.0  
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]  1042   0.0  
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]  1039   0.0  
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi...  1006   0.0  
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]   857   0.0  
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]   857   0.0  
gi|239752618 PREDICTED: similar to promyelocytic leukemia protei...   209   6e-54
gi|30794216 tripartite motif-containing 56 [Homo sapiens]              88   2e-17
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    83   8e-16
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    83   8e-16
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    79   9e-15
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    79   1e-14
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       76   7e-14
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi...    75   2e-13
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi...    75   2e-13
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    66   1e-10
gi|124487387 ring finger protein 207 [Homo sapiens]                    65   2e-10
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    65   2e-10
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               57   5e-08
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               57   5e-08
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              54   4e-07
gi|47174859 tripartite motif-containing 46 [Homo sapiens]              52   2e-06
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             48   2e-05
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    48   3e-05
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    48   3e-05
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]    47   4e-05
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]    47   4e-05

>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
           sapiens]
          Length = 585

 Score = 1187 bits (3071), Expect = 0.0
 Identities = 585/585 (100%), Positives = 585/585 (100%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420

Query: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480
           SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
Sbjct: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480

Query: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLE 540
           RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLE
Sbjct: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLE 540

Query: 541 GPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI 585
           GPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI
Sbjct: 541 GPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI 585


>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
          Length = 633

 Score = 1164 bits (3012), Expect = 0.0
 Identities = 585/633 (92%), Positives = 585/633 (92%), Gaps = 48/633 (7%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL 552
           NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL 600

Query: 553 ADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI 585
           ADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI
Sbjct: 601 ADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI 633


>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
          Length = 882

 Score = 1134 bits (2933), Expect = 0.0
 Identities = 572/621 (92%), Positives = 573/621 (92%), Gaps = 48/621 (7%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL 552
           NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL 600

Query: 553 ADPQAEDRPLVFFDLKIDNES 573
           ADPQAEDRPLVFFDLKIDNE+
Sbjct: 601 ADPQAEDRPLVFFDLKIDNET 621


>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
           sapiens]
          Length = 781

 Score = 1065 bits (2753), Expect = 0.0
 Identities = 524/535 (97%), Positives = 528/535 (98%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420

Query: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480
           SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
Sbjct: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480

Query: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESS 535
           RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENS    ++ +  +SS
Sbjct: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSS 535


>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
          Length = 829

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 524/583 (89%), Positives = 528/583 (90%), Gaps = 48/583 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESS 535
           NSNHVASGAGEAEERVVVISSSEDSDAENS    ++ +  +SS
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSS 583


>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
          Length = 611

 Score = 1039 bits (2687), Expect = 0.0
 Identities = 527/596 (88%), Positives = 532/596 (89%), Gaps = 49/596 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENS-SSRELDDSSSESSDLQLEGPSTLRV 547
           NSNHVASGAGEAEERVVVISSSEDSDAENS S  E+   +  S   + +G    +V
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEVQPRTPASPHFRSQGAQPQQV 596


>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
           sapiens]
          Length = 560

 Score = 1006 bits (2601), Expect = 0.0
 Identities = 504/552 (91%), Positives = 504/552 (91%), Gaps = 48/552 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEA 504
           NSNHVASGAGEA
Sbjct: 541 NSNHVASGAGEA 552


>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
          Length = 435

 Score =  857 bits (2214), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418


>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
          Length = 423

 Score =  857 bits (2214), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418


>gi|239752618 PREDICTED: similar to promyelocytic leukemia protein
           [Homo sapiens]
          Length = 147

 Score =  209 bits (532), Expect = 6e-54
 Identities = 109/130 (83%), Positives = 114/130 (87%), Gaps = 1/130 (0%)

Query: 419 DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPP 478
           DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPP
Sbjct: 3   DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPP 62

Query: 479 SPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENS-SSRELDDSSSESSDL 537
           SPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENS S  E+   +  S   
Sbjct: 63  SPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEVQPRTPASPHF 122

Query: 538 QLEGPSTLRV 547
           + +G    +V
Sbjct: 123 RSQGAQPQQV 132


>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
          Length = 755

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 78/324 (24%), Positives = 129/324 (39%), Gaps = 22/324 (6%)

Query: 54  FLRCQQCQAEAKCPKLLPCLHTLCSGCL----EASGMQCPICQAPWPLGADTPA--LDNV 107
           FL C+ C  + + PK LPCLHT C  CL    +   ++CP C+   P+  +  A    N 
Sbjct: 18  FLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNF 77

Query: 108 FFESL-----QRRLSVYRQIVDAQAVC-----TRCKESADFWCFECEQLLCAKCFEAHQW 157
           F   L      R     R    A A+C     T     A   C +C   LC  C + H+ 
Sbjct: 78  FVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRC 137

Query: 158 FLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCAL 217
             +     + +L       + +  R+     C  P H    L  + C+ CS+ LC  C L
Sbjct: 138 TRQTHTHRVVDLVGYRAGWYDEEARERQAAQC--PQHPGEALRFL-CQPCSQLLCRECRL 194

Query: 218 LDSSHSELKC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE 276
               H +  C  ++  ++ R+  L+ +   +        A       A+ +L    A   
Sbjct: 195 --DPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVG 252

Query: 277 ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRM 336
             + E    V+  + AQ++E+L  + A  +   E    RL  L+   Q  R  +A  +R+
Sbjct: 253 TQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRV 312

Query: 337 KCYASDQEVLDMHGFLRQALCRLR 360
                + E+L + G + Q L +L+
Sbjct: 313 LSLGREAEILSLEGAIAQRLRQLQ 336


>gi|74027251 tripartite motif-containing 33 protein isoform beta
           [Homo sapiens]
          Length = 1110

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)

Query: 25  PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
           P   P+    P PS  P    PAS  +   +  Q  Q+  +  PKLLPCLH+ C  CL  
Sbjct: 97  PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156

Query: 82  ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
                             +   ++CP+C+           +DN F +      S   +  
Sbjct: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211

Query: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
            ++ VCT C+++A    +C EC + LC  C EAHQ   F K       E  ++SV     
Sbjct: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266

Query: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
           G      +FC  P H+   L  ++C  C +  C  C LL+  H E +     E  Q Q+ 
Sbjct: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321

Query: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
            ++ +   L E+ +       Q+   + ++       E+ I+  +  ++  +  + + LL
Sbjct: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381

Query: 299 EAVD 302
           + ++
Sbjct: 382 QQLE 385


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
           [Homo sapiens]
          Length = 1127

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)

Query: 25  PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
           P   P+    P PS  P    PAS  +   +  Q  Q+  +  PKLLPCLH+ C  CL  
Sbjct: 97  PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156

Query: 82  ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
                             +   ++CP+C+           +DN F +      S   +  
Sbjct: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211

Query: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
            ++ VCT C+++A    +C EC + LC  C EAHQ   F K       E  ++SV     
Sbjct: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266

Query: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
           G      +FC  P H+   L  ++C  C +  C  C LL+  H E +     E  Q Q+ 
Sbjct: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321

Query: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
            ++ +   L E+ +       Q+   + ++       E+ I+  +  ++  +  + + LL
Sbjct: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381

Query: 299 EAVD 302
           + ++
Sbjct: 382 QQLE 385


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 114/555 (20%), Positives = 207/555 (37%), Gaps = 84/555 (15%)

Query: 24  PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
           P  E  +E RQ   S    E A  +  +     C  C    +++ PKLLPCLH+ C  CL
Sbjct: 27  PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82

Query: 82  EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
            A                            SG          ++CP+C       A+   
Sbjct: 83  PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139

Query: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
           +DN F +      S    +  +  VCT C+++A+   +C EC + LC  C  AHQ   + 
Sbjct: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197

Query: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
             H  R   E+  ++V     G      +FC  P H+   L  +YC  C K  C  C LL
Sbjct: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249

Query: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
           +  H E +     E  Q Q+  +D +   L E+         Q+   + ++ + + + E+
Sbjct: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307

Query: 278 LIRERVRQVVAHVRAQERELLEAVDA-------RYQRDYEEMASRLGRLDAVLQRIRTGS 330
            I+  +  ++  +  + + LL  +++       +  +  +E+A    +L+ V+   +   
Sbjct: 308 DIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAV 367

Query: 331 ALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCI 390
           +         S + +      L +A C        ++Q       + +    + +L S +
Sbjct: 368 SSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQ---NIINLGSLV 424

Query: 391 TQGKDAAVS-KKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGK 449
            + K++     K +P      + P  +    SN  +    + S  Q   + ++ +    +
Sbjct: 425 IEDKESQPQMPKQNPVVEQNSQPPSGLS---SNQLSKFPTQISLAQLRLQHMQQQQPPPR 481

Query: 450 EARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVV 509
                  SP+   P     V PPH      P +  I  +   PN   +A  A +A ++  
Sbjct: 482 LINFQNHSPKPNGP-----VLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQ 536

Query: 510 VISSSEDSDAENSSS 524
           + S        NS+S
Sbjct: 537 ISSGQGTPSTTNSTS 551



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 16/115 (13%)

Query: 460 QPRPSTSKAVSPPHLDGP-PSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSD 518
           QPRP +++ V  P+   P P    PV  + V  P  +  AS  G                
Sbjct: 615 QPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSR-------------G 661

Query: 519 AENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNES 573
           +  SSS+     S+    + +  P  +R+  EN   P+  D P+V    + D ES
Sbjct: 662 SSGSSSKPAGADSTHKVPVVMLEP--IRIKQENSGPPENYDFPVVIVKQESDEES 714


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 77/326 (23%), Positives = 129/326 (39%), Gaps = 65/326 (19%)

Query: 24  PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
           P  E  +E RQ   S    E A  +  +     C  C    +++ PKLLPCLH+ C  CL
Sbjct: 27  PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82

Query: 82  EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
            A                            SG          ++CP+C       A+   
Sbjct: 83  PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139

Query: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
           +DN F +      S    +  +  VCT C+++A+   +C EC + LC  C  AHQ   + 
Sbjct: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197

Query: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
             H  R   E+  ++V     G      +FC  P H+   L  +YC  C K  C  C LL
Sbjct: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249

Query: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
           +  H E +     E  Q Q+  +D +   L E+         Q+   + ++ + + + E+
Sbjct: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307

Query: 278 LIRERVRQVVAHVRAQERELLEAVDA 303
            I+  +  ++  +  + + LL  +++
Sbjct: 308 DIKVAIFTLMVEINKKGKALLHQLES 333



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 16/115 (13%)

Query: 460 QPRPSTSKAVSPPHLDGP-PSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSD 518
           QPRP +++ V  P+   P P    PV  + V  P  +  AS  G                
Sbjct: 649 QPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSR-------------G 695

Query: 519 AENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNES 573
           +  SSS+     S+    + +  P  +R+  EN   P+  D P+V    + D ES
Sbjct: 696 SSGSSSKPAGADSTHKVPVVMLEP--IRIKQENSGPPENYDFPVVIVKQESDEES 748


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)

Query: 4   APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
           A + SP P +  A  ++ +      PS     S S + +  A    E  + L     C++
Sbjct: 15  AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70

Query: 60  CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
                + P+LLPCLH+ CS CL                  + + + CP+C+         
Sbjct: 71  RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127

Query: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
             ++N F      + +   Q  DA   CT C+++  A  +C EC + LC  C EAHQ   
Sbjct: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185

Query: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
           +   H  R     +++      DG R    ++C+   H    L   +C  C    C  C 
Sbjct: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233

Query: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
           L  ++H + +     +  + Q +L A + + L ++ +       ++ +++ Q+   +   
Sbjct: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291

Query: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
           +  ++  + Q++  +  + R L+   DA  Q+  E    RL R    + +I+     + R
Sbjct: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347

Query: 336 MKCYASDQE 344
              +A + +
Sbjct: 348 FASWALESD 356


>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
           sapiens]
          Length = 580

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 87/403 (21%), Positives = 152/403 (37%), Gaps = 87/403 (21%)

Query: 57  CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
           C  C    K P+LLPCLHT+C+ CLE                                  
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 85  --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
             G+ CP+C  Q   P+G       D  A+++V  ESL+              VC  C +
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140

Query: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
              +  C  C+  LC  C +AH+   K     + +L++      L G +R    I C  P
Sbjct: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192

Query: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
            H    L  ++C  C +P+C  C +    H E  CD ++ +  +      E L      +
Sbjct: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249

Query: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
           +  + A   +H    A   ++    A+        ++ +  H   +++ L +  D R Q+
Sbjct: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306

Query: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEE---- 363
           +   +  +  +L+ +L  +RTG    + +    SD E+L     + + L +L + +    
Sbjct: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTR 365

Query: 364 ----------PQSLQAAVR-TDGFDEFKVRLQDLSSCITQGKD 395
                     PQ      R  + +     +  D + C+ QG+D
Sbjct: 366 PGVNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGED 408


>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
           sapiens]
          Length = 562

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)

Query: 57  CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
           C  C    K P+LLPCLHT+C+ CLE                                  
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 85  --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
             G+ CP+C  Q   P+G       D  A+++V  ESL+              VC  C +
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140

Query: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
              +  C  C+  LC  C +AH+   K     + +L++      L G +R    I C  P
Sbjct: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192

Query: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
            H    L  ++C  C +P+C  C +    H E  CD ++ +  +      E L      +
Sbjct: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249

Query: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
           +  + A   +H    A   ++    A+        ++ +  H   +++ L +  D R Q+
Sbjct: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306

Query: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
           +   +  +  +L+ +L  +RTG    + +    SD E+L
Sbjct: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 86/387 (22%), Positives = 142/387 (36%), Gaps = 79/387 (20%)

Query: 24  PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLE- 82
           PP +      + +  PSP  R    + + QFL C  C    K PK+LPCLHT C  CL+ 
Sbjct: 21  PPCQWSRMASEGTNIPSPVVR----QIDKQFLICSICLERYKNPKVLPCLHTFCERCLQN 76

Query: 83  -----ASGMQCPICQAPWPLGAD-TPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESA 136
                +  + CP+C+    L      AL N FF            I +   V  R     
Sbjct: 77  YIPAHSLTLSCPVCRQTSILPEKGVAALQNNFF------------ITNLMDVLQRT---- 120

Query: 137 DFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRT 196
                                       P +     S+ E +        + C  PNH  
Sbjct: 121 ----------------------------PGSNAEESSILETVTAVAAGKPLSC--PNH-D 149

Query: 197 PTLTSIYCRGCSKPLCCSCALLDSSHSE-----LKCDISAEIQQRQEELDAMTQALQEQD 251
             +   YC+ C   +C  C   +  H+E     LK  +       Q +LDA+ + L E D
Sbjct: 150 GNVMEFYCQSCETAMCRECT--EGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEID 207

Query: 252 SAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEE 311
           SA   +   +H    QL   +A   + I     ++   +  ++  LL  ++  Y   ++ 
Sbjct: 208 SALQFISEIIH----QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV 263

Query: 312 MASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQE-------EP 364
           + S+L  L    + I++ S    +   + ++ EVL +   + + L  L  +       E 
Sbjct: 264 LQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPREN 323

Query: 365 QSLQAAVRTDGFDEFKVRLQDLSSCIT 391
             L   V T+G    K  + +L + +T
Sbjct: 324 DQLDFIVETEG---LKKSIHNLGTILT 347


>gi|124487387 ring finger protein 207 [Homo sapiens]
          Length = 634

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82

Query: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136

Query: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188

Query: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248

Query: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308

Query: 345 VLDM 348
            LD+
Sbjct: 309 FLDL 312


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 84/372 (22%), Positives = 137/372 (36%), Gaps = 79/372 (21%)

Query: 39  PSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLE------ASGMQCPICQ 92
           PSP  R    + + QFL C  C    K PK+LPCLHT C  CL+      +  + CP+C+
Sbjct: 9   PSPVVR----QIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCR 64

Query: 93  APWPLGAD-TPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKC 151
               L      AL N FF            I +   V  R                    
Sbjct: 65  QTSILPEKGVAALQNNFF------------ITNLMDVLQRT------------------- 93

Query: 152 FEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPL 211
                        P +     S+ E +        + C  PNH    +   YC+ C   +
Sbjct: 94  -------------PGSNAEESSILETVTAVAAGKPLSC--PNH-DGNVMEFYCQSCETAM 137

Query: 212 CCSCALLDSSHSE-----LKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG 266
           C  C   +  H+E     LK  +       Q +LDA+ + L E DSA   +   +H    
Sbjct: 138 CRECT--EGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH---- 191

Query: 267 QLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRI 326
           QL   +A   + I     ++   +  ++  LL  ++  Y   ++ + S+L  L    + I
Sbjct: 192 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 251

Query: 327 RTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQE-------EPQSLQAAVRTDGFDEF 379
           ++ S    +   + ++ EVL +   + + L  L  +       E   L   V T+G    
Sbjct: 252 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEG---L 308

Query: 380 KVRLQDLSSCIT 391
           K  + +L + +T
Sbjct: 309 KKSIHNLGTILT 320


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 80/325 (24%), Positives = 129/325 (39%), Gaps = 60/325 (18%)

Query: 33  RQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCL------EASGM 86
           R+ SP P   E  P  +   QFL C  C    +CPK+LPCLHT C  CL      ++  +
Sbjct: 4   REDSPGP---EVQPMDK---QFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTL 57

Query: 87  QCPICQAPWPLGAD-TPALDNVFF-----ESLQRRLSVYRQIVDAQAVCT------RCK- 133
            CP+C+    L      AL N FF     E++Q+         D   +         C  
Sbjct: 58  SCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPN 117

Query: 134 ---ESADFWCFECEQLLCAKCFEA-HQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFC 189
              ++ +F+C  CE  +C +C    H+       R + E    +++  L+  R       
Sbjct: 118 HEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVR------- 170

Query: 190 SNPNHRTPTLTSIYC--RGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQAL 247
                R P L++      G S+        L    +E    ISA  +  ++ L    QAL
Sbjct: 171 ----GRLPQLSAAIALVGGISQQ-------LQERKAEALAQISAAFEDLEQALQQRKQAL 219

Query: 248 -QEQDSAFGAVHAQMHAAV-----GQ--LGRARAETEELIRERVRQVVAHVRAQERELLE 299
             + ++  GA    + + +     GQ  +G + +  E+ +R      V  VR   RE L 
Sbjct: 220 VSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLA 279

Query: 300 AVDARYQRDYEEMASRLGRLDAVLQ 324
           A+ A   + + E      +L+ VL+
Sbjct: 280 ALAA---QAFPERPHENAQLELVLE 301


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 80/325 (24%), Positives = 129/325 (39%), Gaps = 60/325 (18%)

Query: 33  RQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCL------EASGM 86
           R+ SP P   E  P  +   QFL C  C    +CPK+LPCLHT C  CL      ++  +
Sbjct: 4   REDSPGP---EVQPMDK---QFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTL 57

Query: 87  QCPICQAPWPLGAD-TPALDNVFF-----ESLQRRLSVYRQIVDAQAVCT------RCK- 133
            CP+C+    L      AL N FF     E++Q+         D   +         C  
Sbjct: 58  SCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPN 117

Query: 134 ---ESADFWCFECEQLLCAKCFEA-HQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFC 189
              ++ +F+C  CE  +C +C    H+       R + E    +++  L+  R       
Sbjct: 118 HEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVR------- 170

Query: 190 SNPNHRTPTLTSIYC--RGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQAL 247
                R P L++      G S+        L    +E    ISA  +  ++ L    QAL
Sbjct: 171 ----GRLPQLSAAIALVGGISQQ-------LQERKAEALAQISAAFEDLEQALQQRKQAL 219

Query: 248 -QEQDSAFGAVHAQMHAAV-----GQ--LGRARAETEELIRERVRQVVAHVRAQERELLE 299
             + ++  GA    + + +     GQ  +G + +  E+ +R      V  VR   RE L 
Sbjct: 220 VSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLA 279

Query: 300 AVDARYQRDYEEMASRLGRLDAVLQ 324
           A+ A   + + E      +L+ VL+
Sbjct: 280 ALAA---QAFPERPHENAQLELVLE 301


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 76/371 (20%), Positives = 126/371 (33%), Gaps = 58/371 (15%)

Query: 43  ERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCL------EASGMQCPICQAPW- 95
           E  P +EE    L C  C    K P   PC H  C  CL      + S   CP C+A + 
Sbjct: 3   ELCPLAEE----LSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQ 58

Query: 96  --PLGADTPALDNVFFESLQRRLS-------------VYRQIVDAQAVCTRC-KESADFW 139
             P       L NV  + LQ  L+                   +AQ  C  C KE+A   
Sbjct: 59  ARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKT 118

Query: 140 CFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTL 199
           C  C    C +  + H      +  PL       +R       +    FC  P H     
Sbjct: 119 CLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFC--PEH----- 171

Query: 200 TSIYCRGCS-KPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVH 258
           +   C  C  +   CS A L  + ++L+  +  ++     +++  ++AL +  +    V 
Sbjct: 172 SECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVR 231

Query: 259 AQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ------------ 306
              +  V QL +   E + L+          ++ +E+ +    D  YQ            
Sbjct: 232 MTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTL 291

Query: 307 ----------RDYEEMASRLGRLDAVLQR-IRTGSALVQRMKCYASDQEVLDMHGFLRQA 355
                     RD  E   +  +L  +  + +      +         Q  +D+   L+Q 
Sbjct: 292 KEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQC 351

Query: 356 LCRLRQEEPQS 366
           + RL++  P S
Sbjct: 352 IGRLQEPTPSS 362


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 63/256 (24%), Positives = 106/256 (41%), Gaps = 32/256 (12%)

Query: 88  CPICQAPWPLGADTPALDNVFFE-SLQRRLSVYRQIVDAQA--VCTRCKE---SADFWCF 141
           CP CQ    LG     L  +F   +L+R +  YRQ V      +C  CK     A   C 
Sbjct: 130 CPACQGDVELGER--GLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCT 187

Query: 142 ECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTS 201
           EC    C +CF+    +   +A+    L   S R           + C  P+H+     +
Sbjct: 188 ECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFR--------PKGLMC--PDHKEE--VT 235

Query: 202 IYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL-DAMTQALQEQDSAFGAVHAQ 260
            YC+ C + +C  C +  +        + +  Q  +++L  ++T  L  QD+    +  +
Sbjct: 236 HYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQI-CE 294

Query: 261 MHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLD 320
           +  AV     +  + +E + + VR + A +  +   LL+A++       E    RL RL 
Sbjct: 295 LEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIE-------ECQQERLARLS 347

Query: 321 AVLQRIRT---GSALV 333
           A +Q  R+   GS LV
Sbjct: 348 AQIQEHRSLLDGSGLV 363



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 1/34 (2%)

Query: 55 LRCQQCQAEAKCPKLLPCLHTLCSGCL-EASGMQ 87
          L C  CQ   K P +LPC H +C  C  E  G Q
Sbjct: 31 LLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQ 64


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 41/179 (22%), Positives = 75/179 (41%), Gaps = 14/179 (7%)

Query: 129 CTRCKE--SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAEL--RNQSVREFLDGTRKT 184
           C+ CKE  +A   C  C + LC+ C E H    +H   P      R Q     ++G    
Sbjct: 5   CSECKEKRAAHILCTYCNRWLCSSCTEEH----RHSPVPGGPFFPRAQKGSPGVNGGPGD 60

Query: 185 NNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEE-LDAM 243
             ++C  P H T  +  ++C  C    C SC +++  H E +C    E+ Q Q   L+ +
Sbjct: 61  FTLYC--PLH-TQEVLKLFCETCDMLTCHSCLVVE--HKEHRCRHVEEVLQNQRMLLEGV 115

Query: 244 TQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVD 302
           T  +  + S+      Q+   + ++     + E  I+     ++  +  Q   L+E ++
Sbjct: 116 TTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELE 174



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 7   RSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEE 51
           + P+ Q  P  P  P  PPP  P   +QP P   P++   +S+ E
Sbjct: 451 QQPQQQLPPPPPPLPH-PPPPLPPPPQQPHPPLPPSQHLASSQHE 494


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 57/276 (20%)

Query: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCL----EASGMQ------CPICQAPWPLGADTP-- 102
           + C  CQ   + P  + C H  C  CL    E  G        CP+C+ P+  G+  P  
Sbjct: 14  VNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNW 73

Query: 103 ALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQW----- 157
            L NV  E+++R   V    +  + VC    E   F+C + E  LC  C EA +      
Sbjct: 74  QLANV-VENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTM 132

Query: 158 -FLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
            FL+  A P  E  ++ ++  L   R+      S  N R   L +               
Sbjct: 133 RFLEDAAAPYREQIHKCLK-CLRKEREEIQEIQSRENKRMQVLLT--------------- 176

Query: 217 LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE 276
                       +S + QQ   E   + + L+EQ S    + AQ+ +  G + R R E +
Sbjct: 177 -----------QVSTKRQQVISEFAHLRKFLEEQQS---ILLAQLESQDGDILRQRDEFD 222

Query: 277 ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEM 312
            L+   + +  A        L+E ++ + +R   E+
Sbjct: 223 LLVAGEICRFSA--------LIEELEEKNERPAREL 250


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 57/276 (20%)

Query: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCL----EASGMQ------CPICQAPWPLGADTP-- 102
           + C  CQ   + P  + C H  C  CL    E  G        CP+C+ P+  G+  P  
Sbjct: 14  VNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNW 73

Query: 103 ALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQW----- 157
            L NV  E+++R   V    +  + VC    E   F+C + E  LC  C EA +      
Sbjct: 74  QLANV-VENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTM 132

Query: 158 -FLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
            FL+  A P  E  ++ ++  L   R+      S  N R   L +               
Sbjct: 133 RFLEDAAAPYREQIHKCLK-CLRKEREEIQEIQSRENKRMQVLLT--------------- 176

Query: 217 LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE 276
                       +S + QQ   E   + + L+EQ S    + AQ+ +  G + R R E +
Sbjct: 177 -----------QVSTKRQQVISEFAHLRKFLEEQQS---ILLAQLESQDGDILRQRDEFD 222

Query: 277 ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEM 312
            L+   + +  A        L+E ++ + +R   E+
Sbjct: 223 LLVAGEICRFSA--------LIEELEEKNERPAREL 250


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 47/248 (18%), Positives = 95/248 (38%), Gaps = 43/248 (17%)

Query: 57  CQQCQAEAKCPKLLPCLHTLCSGCLEA------SGMQCPICQAPWPLGADTPALDNVFFE 110
           C  C    K P ++ C H  C  C+            CP+C+      +  P        
Sbjct: 29  CSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMV 88

Query: 111 SLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELR 170
            + ++L   ++ +  +++C +  E+   +C+E ++ +C  C  +H     H A  +  L 
Sbjct: 89  EIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISH----THRAHTVVPL- 143

Query: 171 NQSVREFLDGTRKTNNIFCSNP-NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDI 229
           + + +E+ +  +K     C  P   +   +T        KP             ELK  +
Sbjct: 144 DDATQEYKEKLQK-----CLEPLEQKLQEITRCKSSEEKKP------------GELKRLV 186

Query: 230 SAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAH 289
            +  QQ   E + + + L E+                 L R   E ++++ +R+R+  AH
Sbjct: 187 ESRRQQILREFEELHRRLDEEQQVL-------------LSRLEEEEQDIL-QRLRENAAH 232

Query: 290 VRAQEREL 297
           +  + R+L
Sbjct: 233 LGDKRRDL 240


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 47/248 (18%), Positives = 95/248 (38%), Gaps = 43/248 (17%)

Query: 57  CQQCQAEAKCPKLLPCLHTLCSGCLEA------SGMQCPICQAPWPLGADTPALDNVFFE 110
           C  C    K P ++ C H  C  C+            CP+C+      +  P        
Sbjct: 29  CSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMV 88

Query: 111 SLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELR 170
            + ++L   ++ +  +++C +  E+   +C+E ++ +C  C  +H     H A  +  L 
Sbjct: 89  EIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISH----THRAHTVVPL- 143

Query: 171 NQSVREFLDGTRKTNNIFCSNP-NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDI 229
           + + +E+ +  +K     C  P   +   +T        KP             ELK  +
Sbjct: 144 DDATQEYKEKLQK-----CLEPLEQKLQEITRCKSSEEKKP------------GELKRLV 186

Query: 230 SAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAH 289
            +  QQ   E + + + L E+                 L R   E ++++ +R+R+  AH
Sbjct: 187 ESRRQQILREFEELHRRLDEEQQVL-------------LSRLEEEEQDIL-QRLRENAAH 232

Query: 290 VRAQEREL 297
           +  + R+L
Sbjct: 233 LGDKRRDL 240


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.129    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,785,113
Number of Sequences: 37866
Number of extensions: 1432463
Number of successful extensions: 22841
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 723
Number of HSP's that attempted gapping in prelim test: 15926
Number of HSP's gapped (non-prelim): 6314
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.