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Search of human proteins with 154090979
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
(1709 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154090979 hypothetical protein LOC57481 [Homo sapiens] 3396 0.0
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 74 2e-12
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 65 4e-10
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 65 4e-10
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 63 3e-09
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 62 4e-09
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 62 4e-09
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 60 2e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 56 3e-07
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 55 6e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 53 2e-06
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 53 2e-06
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 53 3e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 53 3e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 4e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 4e-06
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 49 3e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 48 9e-05
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 46 3e-04
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 46 4e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 45 5e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 45 5e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 5e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 45 6e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 44 0.001
gi|12232415 hypothetical protein LOC64762 [Homo sapiens] 44 0.001
gi|55741677 SET domain containing 1A [Homo sapiens] 44 0.001
gi|91982772 mucin 17 [Homo sapiens] 44 0.001
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 44 0.001
gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 44 0.001
>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
Length = 1709
Score = 3396 bits (8806), Expect = 0.0
Identities = 1709/1709 (100%), Positives = 1709/1709 (100%)
Query: 1 MRAGWTPRGFSAFHASLLPGRHPYLAHLGPRDRGARIGSRAYSQGCCSCLWLTYKGKKEG 60
MRAGWTPRGFSAFHASLLPGRHPYLAHLGPRDRGARIGSRAYSQGCCSCLWLTYKGKKEG
Sbjct: 1 MRAGWTPRGFSAFHASLLPGRHPYLAHLGPRDRGARIGSRAYSQGCCSCLWLTYKGKKEG 60
Query: 61 STKGELGPAAVTDLEIPSYSRGFLPCTPRFPTTWCRGPGCFCGTAVIAGNLGDLARIVGP 120
STKGELGPAAVTDLEIPSYSRGFLPCTPRFPTTWCRGPGCFCGTAVIAGNLGDLARIVGP
Sbjct: 61 STKGELGPAAVTDLEIPSYSRGFLPCTPRFPTTWCRGPGCFCGTAVIAGNLGDLARIVGP 120
Query: 121 SHHASQLLLLQEQDSGNHPTMAESLSEISDSLDVLEAGDEGKKKCKFKALKSFFVKKKEK 180
SHHASQLLLLQEQDSGNHPTMAESLSEISDSLDVLEAGDEGKKKCKFKALKSFFVKKKEK
Sbjct: 121 SHHASQLLLLQEQDSGNHPTMAESLSEISDSLDVLEAGDEGKKKCKFKALKSFFVKKKEK 180
Query: 181 EAEDTQEEEMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFMLGPEPE 240
EAEDTQEEEMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFMLGPEPE
Sbjct: 181 EAEDTQEEEMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFMLGPEPE 240
Query: 241 RSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAVWVAGP 300
RSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAVWVAGP
Sbjct: 241 RSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAVWVAGP 300
Query: 301 KITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKSLTATQSFSE 360
KITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKSLTATQSFSE
Sbjct: 301 KITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKSLTATQSFSE 360
Query: 361 LSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAARHKMTLNPRKQKKNLQ 420
LSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAARHKMTLNPRKQKKNLQ
Sbjct: 361 LSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAARHKMTLNPRKQKKNLQ 420
Query: 421 VIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPLVSEEEKSITK 480
VIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPLVSEEEKSITK
Sbjct: 421 VIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPLVSEEEKSITK 480
Query: 481 PKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMSAAYGRRWRRK 540
PKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMSAAYGRRWRRK
Sbjct: 481 PKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMSAAYGRRWRRK 540
Query: 541 GASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTS 600
GASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTS
Sbjct: 541 GASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTS 600
Query: 601 QPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGA 660
QPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGA
Sbjct: 601 QPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGA 660
Query: 661 EKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKME 720
EKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKME
Sbjct: 661 EKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKME 720
Query: 721 SAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVS 780
SAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVS
Sbjct: 721 SAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVS 780
Query: 781 SDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQA 840
SDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQA
Sbjct: 781 SDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQA 840
Query: 841 LEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPE 900
LEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPE
Sbjct: 841 LEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPE 900
Query: 901 EQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVE 960
EQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVE
Sbjct: 901 EQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVE 960
Query: 961 QEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPR 1020
QEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPR
Sbjct: 961 QEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPR 1020
Query: 1021 YSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPT 1080
YSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPT
Sbjct: 1021 YSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPT 1080
Query: 1081 PSKYTSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFE 1140
PSKYTSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFE
Sbjct: 1081 PSKYTSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFE 1140
Query: 1141 RAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFM 1200
RAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFM
Sbjct: 1141 RAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFM 1200
Query: 1201 AQQIFSESSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKH 1260
AQQIFSESSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKH
Sbjct: 1201 AQQIFSESSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKH 1260
Query: 1261 PLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKE 1320
PLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKE
Sbjct: 1261 PLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKE 1320
Query: 1321 WRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSV 1380
WRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSV
Sbjct: 1321 WRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSV 1380
Query: 1381 NAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQT 1440
NAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQT
Sbjct: 1381 NAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQT 1440
Query: 1441 STSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQL 1500
STSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQL
Sbjct: 1441 STSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQL 1500
Query: 1501 ASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKT 1560
ASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKT
Sbjct: 1501 ASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKT 1560
Query: 1561 PGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKYEGAGS 1620
PGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKYEGAGS
Sbjct: 1561 PGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKYEGAGS 1620
Query: 1621 ANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTLPAKFQ 1680
ANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTLPAKFQ
Sbjct: 1621 ANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTLPAKFQ 1680
Query: 1681 NPVEPIEPVWFSLARKKAKAWSHMAEITQ 1709
NPVEPIEPVWFSLARKKAKAWSHMAEITQ
Sbjct: 1681 NPVEPIEPVWFSLARKKAKAWSHMAEITQ 1709
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 73.6 bits (179), Expect = 2e-12
Identities = 86/322 (26%), Positives = 137/322 (42%), Gaps = 53/322 (16%)
Query: 147 EISDSLDVLEAGDEGKKKCKFKALKSFFVKKKEKEAEDTQEEEMLELSLSSSNINISSLQ 206
++ ++ + L GKKK KFK K FF KKK KE+ + + S + + +
Sbjct: 10 KLREAAEGLGEDSTGKKKSKFKTFKKFFGKKKRKESPSSTGSSTWKQSQTRNEVIAIESG 69
Query: 207 PV-RENQPTKARAKSSMGSKALSHDSIFMLGPEPERSASKMFPSMDPQRGRPQQRSHISR 265
PV +++ ++ ++GS+ALSHDSIF+ PE + A++ P R Q+ ++
Sbjct: 70 PVGYDSEDELEESRGTLGSRALSHDSIFI--PESGQDATR------PVRVFSQE--NVCD 119
Query: 266 TLPKPRSKVPGVVSGAMSGAVLQNVPTSAVWVAGPKITENPPSRRRRLSIIPPVIQPEII 325
+ + K+ V GP PP PP P
Sbjct: 120 RIKALQLKIQCNVK------------------MGP-----PP---------PPGGLPAKR 147
Query: 326 SKNLVEISLDDESPKNPQKKALPHKSLTATQSFSELSSGPDCSQSLTAFATLASTSSTQL 385
++ S DD P++P + +L H T + S PD T A ++ S +
Sbjct: 148 GEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVS-PDHVSDSTVSARISDNSLAPV 206
Query: 386 PIGFSTPATTQGCLDSSAARHKMTLNPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVT 445
FS PA + CLD+SAA+HK+ + PR Q+ + +R L S Q L C
Sbjct: 207 -ADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSK---MRRLS---SRAQSESLSDLTCTP 259
Query: 446 QTLETPNLDEPLPVEPKEEEPN 467
+ E N ++PL EE P+
Sbjct: 260 E--EEENEEKPLLEVSPEERPS 279
Score = 41.2 bits (95), Expect = 0.009
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 29/242 (11%)
Query: 1478 VRLKRAPPSQ-KYKSEKQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKIS 1536
+R RAP Q K K+ + + +P P+ S H+ G K
Sbjct: 736 LRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAG--PGEREPRKEP 793
Query: 1537 YVADKQQSRPKSESMAKKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVK 1596
A+K RP K P T GQ + P WIT+ +QK++ +
Sbjct: 794 RTAEK---RPLRRGAEKSLPPAATGPGADGQPA------PPWITVTRQKRRGTLDQPPNQ 844
Query: 1597 ELKT-----KSNAGADAETKEPKYEGAGSANENQPKKMFTSSV-----HKQEKTAQMKPP 1646
E K KS G A+ E E A+ + K + V KQ K
Sbjct: 845 EDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKLNFKEG 904
Query: 1647 KPTKSVGFEAQKILQVPAM-EKETKRSSTLPAKFQNPVEPIEPVWFSLARKKAKAWSHMA 1705
+ + Q + Q M EKE + K + +P W LARKK++AWS M
Sbjct: 905 LQ-RGISLSHQNLAQSAVMMEKELHQ-----LKRASYASTDQPSWMELARKKSQAWSDMP 958
Query: 1706 EI 1707
+I
Sbjct: 959 QI 960
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 65.5 bits (158), Expect = 4e-10
Identities = 260/1384 (18%), Positives = 459/1384 (33%), Gaps = 231/1384 (16%)
Query: 460 EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNT 519
E EEE +E K+ + N LG D S +K +TE K T + P+
Sbjct: 86 ESSEEEEEAE--AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK-TGNSMPHP 142
Query: 520 DASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTA 579
++ +S R+ A+ + +S E +G S +G + G +
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-----SVPAFGAAAKPGMVSAGQA- 196
Query: 580 RNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPE 639
D+ + T+S + T + S+K + R A A P P
Sbjct: 197 ------------DSSSEDTSSSSDETDVEVKASEKI-LQVRAASAPAKGTPGKGATPAPP 243
Query: 640 NMDNSMVS---------DPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAE 690
++ S D + E+++ E+T A +L S T+Q A + A E
Sbjct: 244 GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 303
Query: 691 ------AQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTAS 744
A + + +A + S ES + + + KPSG Q AS
Sbjct: 304 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 745 VLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQS 804
S KG A PPR ++ + + DS + EE D E ++
Sbjct: 364 APAKESPR-KG---AAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 419
Query: 805 LGKFEDEQEVFSESKSFVEDLSSS-------------------EEELDLRCLSQALEEPE 845
+ +V S + L + E D S+ +
Sbjct: 420 VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 479
Query: 846 DAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALG---------KPKNQQEVSSASN 896
D EV T + EK + + + P + P Q G KP + E S S+
Sbjct: 480 DGEVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 538
Query: 897 NTPEEQN-----DFMQQLPS-------RCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEP 944
++ + + Q P+ CP + N T +V VGT +
Sbjct: 539 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTAT 596
Query: 945 IPP-RHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGS 1003
P P + ++ SSS +S + EE + + V + + +
Sbjct: 597 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA-------KSVGKGLQVKA 649
Query: 1004 EDIAVERVIS--VEPLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERP 1061
+ V+ + P+LP + ++T + + +S + EE + E + P++
Sbjct: 650 ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE----EAAASPAQVK 705
Query: 1062 KFLDSMSTSAEWSSPVAPTPSKYTSPPW-VTPKFEELYQLSAHPESTTVEEDISKEQLLP 1120
+ A ++ AP+ S P V + Q S V + L
Sbjct: 706 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 765
Query: 1121 RHLSQLTVGNKV----QQLSSNFERAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEK 1176
S +VG V Q + E + + S S + Q K ++ + L
Sbjct: 766 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 825
Query: 1177 MAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLPSKSLSKPEVKH 1236
+P P T +Q S SS+ + SD P + S + KP +
Sbjct: 826 AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPL-- 882
Query: 1237 QVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQ 1296
+F D + +P G ++ R + S SE + L+P
Sbjct: 883 -IFVDP-NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGI 940
Query: 1297 LSQALRKPEYEQKVSP----VSASSPKEWRNSKKQLPPKHSSQASDRSKFQ---PQMSSK 1349
+ + P +++P ASS KE SS+ SD K + Q+S K
Sbjct: 941 RTNVVTMPTAHPRIAPKASMAGASSSKE------------SSRISDGKKQEGPATQVSKK 988
Query: 1350 GPVNVPVKQ----------------------SSGEKH----LPSSSPFQQQVHSSSVNAA 1383
P ++P+ Q SSG LP++SP V + N
Sbjct: 989 NPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL 1048
Query: 1384 ARRSVFE---------SNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTI 1434
+ + E S+ D+ + + + + QG+K+ ++ P + +
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA-HTLVGPTPSRTETLV 1107
Query: 1435 APVRQTSTSGGIYSKKEDLESG--------------------DGNNNQHANLSNQDDVE- 1473
S+ + + + L SG D + + + L+ +DD +
Sbjct: 1108 EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1167
Query: 1474 ---------------KLFGVRLKRAPPSQKYKSEK-------------QDNFTQLASVPS 1505
K G QK + K Q N TQ
Sbjct: 1168 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1227
Query: 1506 GPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKTPGKP- 1564
P++ + + ++ ++ L + + + ++ + ++ QPA +TP
Sbjct: 1228 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1287
Query: 1565 -----AGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPK----- 1614
AG+ + +VS T +K K K KA VKE K K + G+ EP+
Sbjct: 1288 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1347
Query: 1615 ----YEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETK 1670
EG +N K+ S K++K + K K K+ + K + P+ +K+ K
Sbjct: 1348 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA----STKDSESPSQKKKKK 1403
Query: 1671 RSST 1674
+ T
Sbjct: 1404 KKKT 1407
Score = 48.9 bits (115), Expect = 4e-05
Identities = 149/698 (21%), Positives = 245/698 (35%), Gaps = 132/698 (18%)
Query: 451 PNLDEPLPVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDK 510
P P+ V+ K E+P S EE S + E E M +A + + +T+ K
Sbjct: 512 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKACPK 569
Query: 511 KTTDQAP--------NTDASRSQGYPMS-------AAYGRRWRRKGASVSGLSGCEFKGR 555
KT A T A R G S A G + + +S S S E +
Sbjct: 570 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 629
Query: 556 SL-----KQSSEGYGLGDRAGSSPTNK-----TARNVPFSH----LSLEKDNMEQPTTSQ 601
L + S G GL +A S P TA +P ++ + E +S+
Sbjct: 630 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 689
Query: 602 PETTTPQGLLSDKDDMGRRNAGIDFGSRKASA-AQPIPENMDNSM--VSDPQPYHEDAAS 658
E SD ++ A + +K A A P ++ +S P AA
Sbjct: 690 EE--------SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
+++ ++ + ST SV + + + Q +E D ++ +
Sbjct: 742 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEEE 797
Query: 719 MESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEE 778
+S ++ +T+ + KPSG HQ A++ + KG A PP S+ + ++
Sbjct: 798 SDSEEEAETLAQVKPSGKTHQ-IRAALAPAKESPRKG---AAPTPPGKTGPSAAQAGKQD 853
Query: 779 VSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLS 838
DS + EE D E +S +V FV+ S +
Sbjct: 854 ---DSGSSSEESDSDGEAPAAVTS---------AQVIKPPLIFVDPNRSPAGPAATPAQA 901
Query: 839 QALEEPEDAEVFTESSSYVEKYNTSDD------------CSSSEEDLPLRHPAQALGKPK 886
QA P A +ES++ + D+ ++ +P HP A PK
Sbjct: 902 QAASTPRKARA-SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA---PK 957
Query: 887 NQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIP 946
+S+S + + Q+ P+ S+ NP +P + + + E P
Sbjct: 958 ASMAGASSSKESSRISDGKKQEGPATQVSK--KNPA---SLPLTQAALKVLAQKASEAQP 1012
Query: 947 PRHPFQP--WVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSE 1004
P QP V+ V ++SP+S +V+ + K PKL P+VQQ
Sbjct: 1013 PVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL-------PEVQQ------- 1058
Query: 1005 DIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEEG----------TYVEPLPPRCL 1054
+P+S D + S S + E+G T V P P R
Sbjct: 1059 --------------ATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTE 1104
Query: 1055 SQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPWVTP 1092
+ E T+AE S PS+ ++TP
Sbjct: 1105 TLVEE---------TAAESSEDDVVAPSQSLLSGYMTP 1133
Score = 45.1 bits (105), Expect = 6e-04
Identities = 129/670 (19%), Positives = 224/670 (33%), Gaps = 81/670 (12%)
Query: 1035 SESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPWVTPKF 1094
S+ T VE + L R S P++ T + ++P P + + K
Sbjct: 207 SDETDVEVKASEKILQVRAASAPAK--------GTPGKGATPAPPGKAGAVASQTKAGKP 258
Query: 1095 EELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSPLP 1154
EE + S+ S + EE + + LL Q K Q+ + A +P P
Sbjct: 259 EEDSESSSEESSDSEEETPAAKALL-----QAKASGKTSQVGAASAPAKESPRKGAAPAP 313
Query: 1155 PQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRG 1214
P + +++ + + + E S + P Q+ A Q+ + S+ K
Sbjct: 314 PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA----PAQAKPSGKAPQVRAASAPAKES 369
Query: 1215 --SDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQ 1272
AP PP + ++ +V Q DS S++ + + L + Q + PQ
Sbjct: 370 PRKGAAPAPPRKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
Query: 1273 KVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPK- 1331
V S G + P ++ A + + +SS + +S ++P
Sbjct: 429 -VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 487
Query: 1332 ------------HSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSS 1379
+ S +K PQ + GPV V VK EK + +S ++ S+
Sbjct: 488 APAQEKSLGNILQAKPTSSPAKGPPQKA--GPVAVQVK---AEKPMDNSESSEESSDSAD 542
Query: 1380 VNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQ 1439
A + + +A KT + P++ K G T
Sbjct: 543 SEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSS 602
Query: 1440 TSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQ 1499
+ +GG ED S + D E+ G+ A + KS + +
Sbjct: 603 PAVAGGTQRPAEDSSSSE----------ESDSEEEKTGL----AVTVGQAKSVGKGLQVK 648
Query: 1500 LASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACK 1559
ASVP + S+G+G + +L T A+KQ+ SE + + A
Sbjct: 649 AASVP---VKGSLGQG------TAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 699
Query: 1560 TPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKYEGAG 1619
+P + V ++ K + K+ A K +A T A
Sbjct: 700 SPAQ-------------VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT------AAA 740
Query: 1620 SANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTLPAKF 1679
A + P K+ + Q T + P SVG Q +E SS +
Sbjct: 741 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 800
Query: 1680 QNPVEPIEPV 1689
+ E + V
Sbjct: 801 EEEAETLAQV 810
Score = 34.7 bits (78), Expect = 0.82
Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 20/246 (8%)
Query: 177 KKEKEAEDTQEE-EMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFML 235
+K++++E ++EE + E + S + + S + + P ARA S+ G+ + +
Sbjct: 680 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 739
Query: 236 GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAV 295
+RS SK+ P P + S L + + VP V + A Q P
Sbjct: 740 AQAKQRSPSKVKP--------PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED- 790
Query: 296 WVAGPKITENPPSRR-RRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKS-LT 353
+G E+ L+ + P + I L ESP+ P K+ +
Sbjct: 791 --SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK---ESPRKGAAPTPPGKTGPS 845
Query: 354 ATQSFSELSSGPDCSQSLTAFATLASTSSTQL---PIGFSTPATTQGCLDSSAARHKMTL 410
A Q+ + SG +S + A+ +S Q+ P+ F P + ++ A+ +
Sbjct: 846 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 905
Query: 411 NPRKQK 416
PRK +
Sbjct: 906 TPRKAR 911
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 65.5 bits (158), Expect = 4e-10
Identities = 261/1384 (18%), Positives = 459/1384 (33%), Gaps = 232/1384 (16%)
Query: 460 EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNT 519
E EEE +E K+ + N LG D S +K +TE K T + P+
Sbjct: 86 ESSEEEEEAE--AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK-TGNSMPHP 142
Query: 520 DASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTA 579
++ +S R+ A+ + +S E +G S +G + G +
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-----SVPAFGAAAKPGMVSAGQA- 196
Query: 580 RNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPE 639
D+ + T+S + T + S+K + R A A P P
Sbjct: 197 ------------DSSSEDTSSSSDETDVEVKASEKI-LQVRAASAPAKGTPGKGATPAPP 243
Query: 640 NMDNSMVS---------DPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAE 690
++ S D + E+++ E+T A +L S T+Q A + A E
Sbjct: 244 GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 303
Query: 691 ------AQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTAS 744
A + + +A + S ES + + + KPSG Q AS
Sbjct: 304 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 745 VLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQS 804
S KG A PPR ++ + + DS + EE D E ++
Sbjct: 364 APAKESPR-KG---AAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 419
Query: 805 LGKFEDEQEVFSESKSFVEDLSSS-------------------EEELDLRCLSQALEEPE 845
+ +V S + L + E D S+ +
Sbjct: 420 VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 479
Query: 846 DAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALG---------KPKNQQEVSSASN 896
D EV T + EK + + + P + P Q G KP + E S S+
Sbjct: 480 DGEVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 538
Query: 897 NTPEEQN-----DFMQQLPS-------RCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEP 944
++ + + Q P+ CP + N T +V VGT +
Sbjct: 539 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTAT 596
Query: 945 IPP-RHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGS 1003
P P + ++ SSS +S + EE + + V + + +
Sbjct: 597 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA-------KSVGKGLQVKA 649
Query: 1004 EDIAVERVIS--VEPLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERP 1061
+ V+ + P+LP + ++T + + +S + EE + E + P++
Sbjct: 650 ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE----EAAASPAQVK 705
Query: 1062 KFLDSMSTSAEWSSPVAPTPSKYTSPPW-VTPKFEELYQLSAHPESTTVEEDISKEQLLP 1120
+ A ++ AP+ S P V + Q S V + L
Sbjct: 706 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 765
Query: 1121 RHLSQLTVGNKV----QQLSSNFERAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEK 1176
S +VG V Q + E + + S S + Q K ++ + L
Sbjct: 766 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 825
Query: 1177 MAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLPSKSLSKPEVKH 1236
+P P T +Q S SS+ + SD P + S + KP +
Sbjct: 826 AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPL-- 882
Query: 1237 QVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQ 1296
+F D + +P G ++ R + S SE + L+P
Sbjct: 883 -IFVDP-NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGI 940
Query: 1297 LSQALRKPEYEQKVSP----VSASSPKEWRNSKKQLPPKHSSQASDRSKFQ---PQMSSK 1349
+ + P +++P ASS KE SS+ SD K + Q+S K
Sbjct: 941 RTNVVTMPTAHPRIAPKASMAGASSSKE------------SSRISDGKKQEGPATQVSKK 988
Query: 1350 GPVNVPVKQ----------------------SSGEKH----LPSSSPFQQQVHSSSVNAA 1383
P ++P+ Q SSG LP++SP V + N
Sbjct: 989 NPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL 1048
Query: 1384 ARRSVFE---------SNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTI 1434
+ + E S+ D+ + + + + QG+K+ P P+ + +
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRT--ETLV 1106
Query: 1435 APVRQTSTSGGIYSKKEDLESG--------------------DGNNNQHANLSNQDDVE- 1473
S+ + + + L SG D + + + L+ +DD +
Sbjct: 1107 EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1166
Query: 1474 ---------------KLFGVRLKRAPPSQKYKSEK-------------QDNFTQLASVPS 1505
K G QK + K Q N TQ
Sbjct: 1167 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1226
Query: 1506 GPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKTPGKP- 1564
P++ + + ++ ++ L + + + ++ + ++ QPA +TP
Sbjct: 1227 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1286
Query: 1565 -----AGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPK----- 1614
AG+ + +VS T +K K K KA VKE K K + G+ EP+
Sbjct: 1287 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1346
Query: 1615 ----YEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETK 1670
EG +N K+ S K++K + K K K+ + K + P+ +K+ K
Sbjct: 1347 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA----STKDSESPSQKKKKK 1402
Query: 1671 RSST 1674
+ T
Sbjct: 1403 KKKT 1406
Score = 48.1 bits (113), Expect = 7e-05
Identities = 128/593 (21%), Positives = 214/593 (36%), Gaps = 92/593 (15%)
Query: 451 PNLDEPLPVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDK 510
P P+ V+ K E+P S EE S + E E M +A + + +T+ K
Sbjct: 512 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKACPK 569
Query: 511 KTTDQAP--------NTDASRSQGYPMS-------AAYGRRWRRKGASVSGLSGCEFKGR 555
KT A T A R G S A G + + +S S S E +
Sbjct: 570 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 629
Query: 556 SL-----KQSSEGYGLGDRAGSSPTNK-----TARNVPFSH----LSLEKDNMEQPTTSQ 601
L + S G GL +A S P TA +P ++ + E +S+
Sbjct: 630 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 689
Query: 602 PETTTPQGLLSDKDDMGRRNAGIDFGSRKASA-AQPIPENMDNSM--VSDPQPYHEDAAS 658
E SD ++ A + +K A A P ++ +S P AA
Sbjct: 690 EE--------SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
+++ ++ + ST SV + + + Q +E D ++ +
Sbjct: 742 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEEE 797
Query: 719 MESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEE 778
+S ++ +T+ + KPSG HQ A++ + KG A PP S+ + ++
Sbjct: 798 SDSEEEAETLAQVKPSGKTHQ-IRAALAPAKESPRKG---AAPTPPGKTGPSAAQAGKQD 853
Query: 779 VSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLS 838
DS + EE D E +S +V FV+ S +
Sbjct: 854 ---DSGSSSEESDSDGEAPAAVTS---------AQVIKPPLIFVDPNRSPAGPAATPAQA 901
Query: 839 QALEEPEDAEVFTESSSYVEKYNTSDD------------CSSSEEDLPLRHPAQALGKPK 886
QA P A +ES++ + D+ ++ +P HP A PK
Sbjct: 902 QAASTPRKARA-SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA---PK 957
Query: 887 NQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIP 946
+S+S + + Q+ P+ S+ NP +P + + + E P
Sbjct: 958 ASMAGASSSKESSRISDGKKQEGPATQVSK--KNPA---SLPLTQAALKVLAQKASEAQP 1012
Query: 947 PRHPFQP--WVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQ 997
P QP V+ V ++SP+S +V+ + K PKL P+VQQ
Sbjct: 1013 PVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL-------PEVQQ 1058
Score = 45.1 bits (105), Expect = 6e-04
Identities = 129/670 (19%), Positives = 224/670 (33%), Gaps = 81/670 (12%)
Query: 1035 SESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPWVTPKF 1094
S+ T VE + L R S P++ T + ++P P + + K
Sbjct: 207 SDETDVEVKASEKILQVRAASAPAK--------GTPGKGATPAPPGKAGAVASQTKAGKP 258
Query: 1095 EELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSPLP 1154
EE + S+ S + EE + + LL Q K Q+ + A +P P
Sbjct: 259 EEDSESSSEESSDSEEETPAAKALL-----QAKASGKTSQVGAASAPAKESPRKGAAPAP 313
Query: 1155 PQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRG 1214
P + +++ + + + E S + P Q+ A Q+ + S+ K
Sbjct: 314 PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA----PAQAKPSGKAPQVRAASAPAKES 369
Query: 1215 --SDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQ 1272
AP PP + ++ +V Q DS S++ + + L + Q + PQ
Sbjct: 370 PRKGAAPAPPRKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
Query: 1273 KVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPK- 1331
V S G + P ++ A + + +SS + +S ++P
Sbjct: 429 -VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 487
Query: 1332 ------------HSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSS 1379
+ S +K PQ + GPV V VK EK + +S ++ S+
Sbjct: 488 APAQEKSLGNILQAKPTSSPAKGPPQKA--GPVAVQVK---AEKPMDNSESSEESSDSAD 542
Query: 1380 VNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQ 1439
A + + +A KT + P++ K G T
Sbjct: 543 SEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSS 602
Query: 1440 TSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQ 1499
+ +GG ED S + D E+ G+ A + KS + +
Sbjct: 603 PAVAGGTQRPAEDSSSSE----------ESDSEEEKTGL----AVTVGQAKSVGKGLQVK 648
Query: 1500 LASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACK 1559
ASVP + S+G+G + +L T A+KQ+ SE + + A
Sbjct: 649 AASVP---VKGSLGQG------TAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 699
Query: 1560 TPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKYEGAG 1619
+P + V ++ K + K+ A K +A T A
Sbjct: 700 SPAQ-------------VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT------AAA 740
Query: 1620 SANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTLPAKF 1679
A + P K+ + Q T + P SVG Q +E SS +
Sbjct: 741 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 800
Query: 1680 QNPVEPIEPV 1689
+ E + V
Sbjct: 801 EEEAETLAQV 810
Score = 35.8 bits (81), Expect = 0.37
Identities = 117/606 (19%), Positives = 202/606 (33%), Gaps = 93/606 (15%)
Query: 177 KKEKEAEDTQEE-EMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFML 235
+K++++E ++EE + E + S + + S + + P ARA S+ G+ + +
Sbjct: 680 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 739
Query: 236 GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAV 295
+RS SK+ P P + S L + + VP V + A Q P
Sbjct: 740 AQAKQRSPSKVKP--------PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED- 790
Query: 296 WVAGPKITENPPSRR-RRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKS-LT 353
+G E+ L+ + P + I L ESP+ P K+ +
Sbjct: 791 --SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK---ESPRKGAAPTPPGKTGPS 845
Query: 354 ATQSFSELSSGPDCSQSLTAFATLASTSSTQL---PIGFSTPATTQGCLDSSAARHKMTL 410
A Q+ + SG +S + A+ +S Q+ P+ F P + ++ A+ +
Sbjct: 846 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 905
Query: 411 NPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPL 470
PRK + + S + ++ + QC+T + T + P + ++
Sbjct: 906 TPRKARASESTARSSSSE--SEDEDVIPAT-QCLTPGIRTNVVTMPTAHPRIAPKASMAG 962
Query: 471 VSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMS 530
S ++S S S +KQ KK P T A+
Sbjct: 963 ASSSKES---------------SRISDGKKQEGPATQVSKKNPASLPLTQAA-------- 999
Query: 531 AAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLE 590
K + R+ S +G +SP + + + + L
Sbjct: 1000 --------LKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1051
Query: 591 KDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQ 650
K Q T PE++ SD + G++ A P P + +
Sbjct: 1052 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV----- 1106
Query: 651 PYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSF 710
E AA +E S SL+ +M P Q +
Sbjct: 1107 --EETAAESSEDDVVAPSQSLL-------------------SGYMTPGLTPANSQAS--- 1142
Query: 711 DLQKAQSKMESAQDVQT--ICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLF 768
KA K++S+ V + K+ P G + GM S G A P
Sbjct: 1143 ---KATPKLDSSPSVSSTLAAKDDPDGK-QEAKPQQAAGMLSPKTGGKEAASGTTP---- 1194
Query: 769 QSSRKP 774
Q SRKP
Sbjct: 1195 QKSRKP 1200
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 62.8 bits (151), Expect = 3e-09
Identities = 262/1390 (18%), Positives = 457/1390 (32%), Gaps = 236/1390 (16%)
Query: 458 PVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAP 517
P + E N LVSE E+ + P K GM SA + + + D+ + P
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 518 NTDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNK 577
+ ++ + +S RK A G G + +G G+ P K
Sbjct: 217 SVKPAQVKASSVSTKESPA--RKAAPAPGKVG------DVTPQVKG-------GALPPAK 261
Query: 578 TARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGR----RNAGIDFGSRKASA 633
A+ E+++ S+ E P G S + R A
Sbjct: 262 RAKKP-------EEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 634 AQPIPENMDNSMVS---------DPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAI 684
A P P ++ S D + E+++ E+T A +L S T+Q A
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 685 LSVAAE------AQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVH 738
+ A E A + + +A + S ES + + + KPSG
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 739 QTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAH 798
Q AS S KG A PPR ++ + + DS + EE D E
Sbjct: 435 QVRAASAPAKESPR-KG---AAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
Query: 799 GHSSQSLGKFEDEQEVFSESKSFVEDLSSS-------------------EEELDLRCLSQ 839
++ + +V S + L + E D S+
Sbjct: 491 AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSE 550
Query: 840 ALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALG---------KPKNQQE 890
+ D EV T + EK + + + P + P Q G KP + E
Sbjct: 551 ESSDSSDGEVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE 609
Query: 891 VSSASNNTPEEQN-----DFMQQLPS-------RCPSQPIMNPTVQQQVPTSSVGTSIKQ 938
S S+++ + + Q P+ CP + N T +V VGT +
Sbjct: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPR 667
Query: 939 SDSVEPIPP-RHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQ 997
P P + ++ SSS +S + EE + + V +
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA-------KSVGK 720
Query: 998 NMFSGSEDIAVERVIS--VEPLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLS 1055
+ + + V+ + P+LP + ++T + + +S + EE + E +
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE----EAAA 776
Query: 1056 QPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPW-VTPKFEELYQLSAHPESTTVEEDIS 1114
P++ + A ++ AP+ S P V + Q S V +
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1115 KEQLLPRHLSQLTVGNKV----QQLSSNFERAAIEADISGSPLPPQYATQFLKRSKVQEM 1170
L S +VG V Q + E + + S S + Q K ++
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
Query: 1171 TSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLPSKSLS 1230
+ L +P P T +Q S SS+ + SD P + S +
Sbjct: 897 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVI 955
Query: 1231 KPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKE 1290
KP + +F D + +P G ++ R + S SE +
Sbjct: 956 KPPL---IFVDP-NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ 1011
Query: 1291 QLSPRQLSQALRKPEYEQKVSP----VSASSPKEWRNSKKQLPPKHSSQASDRSKFQ--- 1343
L+P + + P +++P ASS KE SS+ SD K +
Sbjct: 1012 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE------------SSRISDGKKQEGPA 1059
Query: 1344 PQMSSKGPVNVPVKQ----------------------SSGEKH----LPSSSPFQQQVHS 1377
Q+S K P ++P+ Q SSG LP++SP V +
Sbjct: 1060 TQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQA 1119
Query: 1378 SSVNAAARRSVFE---------SNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATK 1428
N + + E S+ D+ + + + + QG+K+ P P+
Sbjct: 1120 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRT 1179
Query: 1429 PGKFTIAPVRQTSTSGGIYSKKEDLESG--------------------DGNNNQHANLSN 1468
+ + S+ + + + L SG D + + + L+
Sbjct: 1180 --ETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1237
Query: 1469 QDDVE----------------KLFGVRLKRAPPSQKYKSEK-------------QDNFTQ 1499
+DD + K G QK + K Q N TQ
Sbjct: 1238 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1297
Query: 1500 LASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACK 1559
P++ + + ++ ++ L + + + ++ + ++ QPA +
Sbjct: 1298 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1357
Query: 1560 TPGKP------AGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEP 1613
TP AG+ + +VS T +K K K KA VKE K K + G+ EP
Sbjct: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1417
Query: 1614 K---------YEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPA 1664
+ EG +N K+ S K++K + K K K+ + K + P+
Sbjct: 1418 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA----STKDSESPS 1473
Query: 1665 MEKETKRSST 1674
+K+ K+ T
Sbjct: 1474 QKKKKKKKKT 1483
Score = 48.1 bits (113), Expect = 7e-05
Identities = 128/593 (21%), Positives = 214/593 (36%), Gaps = 92/593 (15%)
Query: 451 PNLDEPLPVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDK 510
P P+ V+ K E+P S EE S + E E M +A + + +T+ K
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKACPK 646
Query: 511 KTTDQAP--------NTDASRSQGYPMS-------AAYGRRWRRKGASVSGLSGCEFKGR 555
KT A T A R G S A G + + +S S S E +
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 556 SL-----KQSSEGYGLGDRAGSSPTNK-----TARNVPFSH----LSLEKDNMEQPTTSQ 601
L + S G GL +A S P TA +P ++ + E +S+
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 602 PETTTPQGLLSDKDDMGRRNAGIDFGSRKASA-AQPIPENMDNSM--VSDPQPYHEDAAS 658
E SD ++ A + +K A A P ++ +S P AA
Sbjct: 767 EE--------SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
+++ ++ + ST SV + + + Q +E D ++ +
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEEE 874
Query: 719 MESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEE 778
+S ++ +T+ + KPSG HQ A++ + KG A PP S+ + ++
Sbjct: 875 SDSEEEAETLAQVKPSGKTHQ-IRAALAPAKESPRKG---AAPTPPGKTGPSAAQAGKQD 930
Query: 779 VSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLS 838
DS + EE D E +S +V FV+ S +
Sbjct: 931 ---DSGSSSEESDSDGEAPAAVTS---------AQVIKPPLIFVDPNRSPAGPAATPAQA 978
Query: 839 QALEEPEDAEVFTESSSYVEKYNTSDD------------CSSSEEDLPLRHPAQALGKPK 886
QA P A +ES++ + D+ ++ +P HP A PK
Sbjct: 979 QAASTPRKARA-SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA---PK 1034
Query: 887 NQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIP 946
+S+S + + Q+ P+ S+ NP +P + + + E P
Sbjct: 1035 ASMAGASSSKESSRISDGKKQEGPATQVSK--KNPA---SLPLTQAALKVLAQKASEAQP 1089
Query: 947 PRHPFQP--WVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQ 997
P QP V+ V ++SP+S +V+ + K PKL P+VQQ
Sbjct: 1090 PVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL-------PEVQQ 1135
Score = 46.2 bits (108), Expect = 3e-04
Identities = 133/677 (19%), Positives = 227/677 (33%), Gaps = 81/677 (11%)
Query: 1036 ESTAVEEGTYVEP-LPPRCLSQPSERPKFLDSMSTSA-------EWSSPVAPTPSKYTSP 1087
ES + EEG+ E P SQ K L + SA + ++P P + +
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328
Query: 1088 PWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEAD 1147
K EE + S+ S + EE + + LL Q K Q+ + A
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALL-----QAKASGKTSQVGAASAPAKESPR 383
Query: 1148 ISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSE 1207
+P PP + +++ + + + E S + P Q+ A Q+ +
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA----PAQAKPSGKAPQVRAA 439
Query: 1208 SSALKRG--SDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSL 1265
S+ K AP PP + ++ +V Q DS S++ + + L + Q
Sbjct: 440 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALAAMNAAQVK 498
Query: 1266 GRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSK 1325
+ PQ V S G + P ++ A + + +SS + +S
Sbjct: 499 PLGKSPQ-VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
Query: 1326 KQLPPK-------------HSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQ 1372
++P + S +K PQ + GPV V VK EK + +S +
Sbjct: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA--GPVAVQVK---AEKPMDNSESSE 612
Query: 1373 QQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKF 1432
+ S+ A + + +A KT + P++ K G
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 1433 TIAPVRQTSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSE 1492
T + +GG ED S + D E+ G+ A + KS
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSE----------ESDSEEEKTGL----AVTVGQAKSV 718
Query: 1493 KQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMA 1552
+ + ASVP + S+G+G + +L T A+KQ+ SE +
Sbjct: 719 GKGLQVKAASVP---VKGSLGQG------TAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 1553 KKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKE 1612
+ A +P + V ++ K + K+ A K +A T
Sbjct: 770 DSEEAAASPAQ-------------VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT-- 814
Query: 1613 PKYEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRS 1672
A A + P K+ + Q T + P SVG Q +E S
Sbjct: 815 ----AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS 870
Query: 1673 STLPAKFQNPVEPIEPV 1689
S + + E + V
Sbjct: 871 SEEESDSEEEAETLAQV 887
Score = 36.6 bits (83), Expect = 0.21
Identities = 213/1054 (20%), Positives = 359/1054 (34%), Gaps = 134/1054 (12%)
Query: 460 EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNT 519
E EEE +E K+ + N LG D S +K +TE K T + P+
Sbjct: 86 ESSEEEEEAE--AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK-TGNSMPHP 142
Query: 520 DASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTA 579
++ +S R+ A+ + +S E +G S +G + G +
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-----SVPAFGAAAKPGMVSAGQAD 197
Query: 580 RNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNA------GIDFGSRKASA 633
+ + S ++ ++E + +P + S K+ R+ A G K A
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSV-STKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 634 AQPI-----PENMDNSMVSDPQPYHEDAASGAEKTEARASLSLM------VESLSTTQEE 682
P PE S S+ E+ A +++ +AS ++ + T +
Sbjct: 257 LPPAKRAKKPEEESES--SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 683 AILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFT 742
A + +A + + ++++ S + + S+ E+ + + + K SG Q
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA-AKALLQAKASGKTSQVGA 373
Query: 743 ASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSS 802
AS S KG A PP + K A + DS++ EE D SEE A +
Sbjct: 374 ASAPAKESPR-KG---AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD-SEEEAPAQAK 428
Query: 803 QSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNT 862
S GK +V + S E R A + + + +S S +
Sbjct: 429 PS-GK---APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS------S 478
Query: 863 SDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPT 922
S++ S E L + AQ K+ Q V AS M P + P+
Sbjct: 479 SEESDSDREALAAMNAAQVKPLGKSPQ-VKPAST---------MGMGPLGKGAGPVPPGK 528
Query: 923 VQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLP 982
V P++ VG + S+S E SS V +++ P
Sbjct: 529 VGPATPSAQVGKWEEDSES------------------SSEESSDSSDGEVPTAVA--PAQ 568
Query: 983 PKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEE 1042
K L ++ K + G A + V+ P + +S + SE A
Sbjct: 569 EKSLGN-ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE-APAA 626
Query: 1043 GTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAP------TPSK---YTSPPWVTPK 1093
T + P + Q PK T+ S+ VAP P K TSP +P
Sbjct: 627 MTAAQAKPALKIPQTKACPK-----KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
Query: 1094 FEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGS-- 1151
Q A S++ E D +E + +TVG + + + + A + GS
Sbjct: 682 VAGGTQRPAEDSSSSEESDSEEE----KTGLAVTVG-QAKSVGKGLQVKAASVPVKGSLG 736
Query: 1152 ------------PLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKF 1199
P Q + + S+ E S E+ A K+ + + TQ+
Sbjct: 737 QGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSV--KKTQAKANP 794
Query: 1200 MAQQIFSESSALKRGSDVAPLPPNLPSKSLS--KPEVKH----QVFSDSGSANPKGG--I 1251
A + S + V +S S KP V++ V + ++ P G +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
Query: 1252 SSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVS 1311
++ P + G E+ +E S K L+ A P +
Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
Query: 1312 PVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVP---VKQSSGEKHLPSS 1368
P + P + KQ SS+ SD P + V P + P++
Sbjct: 915 PPGKTGPSA-AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 973
Query: 1369 SPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATK 1428
+P Q Q S+ A A S S+S DE T+ + G + + ++P +
Sbjct: 974 TPAQAQAASTPRKARASESTARSSSSE---SEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1429 PGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNNQ 1462
IAP ++ G S KE DG +
Sbjct: 1031 -----IAP---KASMAGASSSKESSRISDGKKQE 1056
Score = 35.8 bits (81), Expect = 0.37
Identities = 117/606 (19%), Positives = 202/606 (33%), Gaps = 93/606 (15%)
Query: 177 KKEKEAEDTQEE-EMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFML 235
+K++++E ++EE + E + S + + S + + P ARA S+ G+ + +
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 236 GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAV 295
+RS SK+ P P + S L + + VP V + A Q P
Sbjct: 817 AQAKQRSPSKVKP--------PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED- 867
Query: 296 WVAGPKITENPPSRR-RRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKS-LT 353
+G E+ L+ + P + I L ESP+ P K+ +
Sbjct: 868 --SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK---ESPRKGAAPTPPGKTGPS 922
Query: 354 ATQSFSELSSGPDCSQSLTAFATLASTSSTQL---PIGFSTPATTQGCLDSSAARHKMTL 410
A Q+ + SG +S + A+ +S Q+ P+ F P + ++ A+ +
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 982
Query: 411 NPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPL 470
PRK + + S + ++ + QC+T + T + P + ++
Sbjct: 983 TPRKARASESTARSSSSE--SEDEDVIPAT-QCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 471 VSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMS 530
S ++S S S +KQ KK P T A+
Sbjct: 1040 ASSSKES---------------SRISDGKKQEGPATQVSKKNPASLPLTQAA-------- 1076
Query: 531 AAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLE 590
K + R+ S +G +SP + + + + L
Sbjct: 1077 --------LKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1128
Query: 591 KDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQ 650
K Q T PE++ SD + G++ A P P + +
Sbjct: 1129 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV----- 1183
Query: 651 PYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSF 710
E AA +E S SL+ +M P Q +
Sbjct: 1184 --EETAAESSEDDVVAPSQSLL-------------------SGYMTPGLTPANSQAS--- 1219
Query: 711 DLQKAQSKMESAQDVQT--ICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLF 768
KA K++S+ V + K+ P G + GM S G A P
Sbjct: 1220 ---KATPKLDSSPSVSSTLAAKDDPDGK-QEAKPQQAAGMLSPKTGGKEAASGTTP---- 1271
Query: 769 QSSRKP 774
Q SRKP
Sbjct: 1272 QKSRKP 1277
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 62.4 bits (150), Expect = 4e-09
Identities = 258/1358 (18%), Positives = 449/1358 (33%), Gaps = 209/1358 (15%)
Query: 458 PVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAP 517
P + E N LVSE E+ + P K GM SA + + + D+ + P
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 518 NTDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNK 577
+ ++ + +S RK A G G + +G G+ P K
Sbjct: 217 SVKPAQVKASSVSTKESPA--RKAAPAPGKVG------DVTPQVKG-------GALPPAK 261
Query: 578 TARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGR----RNAGIDFGSRKASA 633
A+ E+++ S+ E P G S + R A
Sbjct: 262 RAKKP-------EEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 634 AQPIPENMDNSMVS---------DPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAI 684
A P P ++ S D + E+++ E+T A +L S T+Q A
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 685 LSVAAE------AQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVH 738
+ A E A + + +A + S ES + + + KPSG
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 739 QTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAH 798
Q AS S KG A PPR ++ + + DS + EE D E
Sbjct: 435 QVRAASAPAKESPR-KG---AAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
Query: 799 GHSSQSLGKFEDEQEVFSESKSFVEDLSSS-------------------EEELDLRCLSQ 839
++ + +V S + L + E D S+
Sbjct: 491 AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSE 550
Query: 840 ALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALG---------KPKNQQE 890
+ D EV T + EK + + + P + P Q G KP + E
Sbjct: 551 ESSDSSDGEVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE 609
Query: 891 VSSASNNTPEEQN-----DFMQQLPS-------RCPSQPIMNPTVQQQVPTSSVGTSIKQ 938
S S+++ + + Q P+ CP + N T +V VGT +
Sbjct: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPR 667
Query: 939 SDSVEPIPP-RHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQ 997
P P + ++ SSS +S + EE + + V +
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA-------KSVGK 720
Query: 998 NMFSGSEDIAVERVIS--VEPLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLS 1055
+ + + V+ + P+LP + ++T + + +S + EE + E +
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE----EAAA 776
Query: 1056 QPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPW-VTPKFEELYQLSAHPESTTVEEDIS 1114
P++ + A ++ AP+ S P V + Q S V +
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1115 KEQLLPRHLSQLTVGNKV----QQLSSNFERAAIEADISGSPLPPQYATQFLKRSKVQEM 1170
L S +VG V Q + E + + S S + Q K ++
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
Query: 1171 TSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLPSKSLS 1230
+ L +P P T +Q S SS+ + SD P + S +
Sbjct: 897 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVI 955
Query: 1231 KPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKE 1290
KP + +F D + +P G P P Q+ P+K + SE SS E
Sbjct: 956 KPPL---IFVDP-NRSPAG-------PAATPAQAQAA-STPRKARA-SESTARSSSSESE 1002
Query: 1291 QLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKG 1350
+Q L P V + + P+ + PK S + SK ++S
Sbjct: 1003 DEDVIPATQCLT-PGIRTNVVTMPTAHPR--------IAPKASMAGASSSKESSRISDGK 1053
Query: 1351 PVNVPVKQ-SSGEKHLPSSSPFQQQVHSSSVNAAARRSVFE---------SNSDNWFLGR 1400
P Q S LP++SP V + N + + E S+ D+
Sbjct: 1054 KQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSD 1113
Query: 1401 DEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQTSTSGGIYSKKEDLESG---- 1456
+ + + + QG+K+ ++ P + + S+ + + + L SG
Sbjct: 1114 SSSGSEEDGEGPQGAKSA-HTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP 1172
Query: 1457 ----------------DGNNNQHANLSNQDDVE----------------KLFGVRLKRAP 1484
D + + + L+ +DD + K G
Sbjct: 1173 GLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGT 1232
Query: 1485 PSQKYKSEK-------------QDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGN 1531
QK + K Q N TQ P++ + + ++ ++ L
Sbjct: 1233 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1292
Query: 1532 LTKISYVADKQQSRPKSESMAKKQPACKTPGKP------AGQQSDYAVSEPVWITMAKQK 1585
+ + + ++ + ++ QPA +TP AG+ + +VS T +K K
Sbjct: 1293 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1352
Query: 1586 QKSFKAHISVKELKTKSNAGADAETKEPK---------YEGAGSANENQPKKMFTSSVHK 1636
K KA VKE K K + G+ EP+ EG +N K+ S K
Sbjct: 1353 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1412
Query: 1637 QEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSST 1674
++K + K K K+ + K + P+ +K+ K+ T
Sbjct: 1413 KDKEKKEKKKKAKKA----STKDSESPSQKKKKKKKKT 1446
Score = 46.2 bits (108), Expect = 3e-04
Identities = 133/677 (19%), Positives = 227/677 (33%), Gaps = 81/677 (11%)
Query: 1036 ESTAVEEGTYVEP-LPPRCLSQPSERPKFLDSMSTSA-------EWSSPVAPTPSKYTSP 1087
ES + EEG+ E P SQ K L + SA + ++P P + +
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328
Query: 1088 PWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEAD 1147
K EE + S+ S + EE + + LL Q K Q+ + A
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALL-----QAKASGKTSQVGAASAPAKESPR 383
Query: 1148 ISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSE 1207
+P PP + +++ + + + E S + P Q+ A Q+ +
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA----PAQAKPSGKAPQVRAA 439
Query: 1208 SSALKRG--SDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSL 1265
S+ K AP PP + ++ +V Q DS S++ + + L + Q
Sbjct: 440 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALAAMNAAQVK 498
Query: 1266 GRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSK 1325
+ PQ V S G + P ++ A + + +SS + +S
Sbjct: 499 PLGKSPQ-VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
Query: 1326 KQLPPK-------------HSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQ 1372
++P + S +K PQ + GPV V VK EK + +S +
Sbjct: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA--GPVAVQVK---AEKPMDNSESSE 612
Query: 1373 QQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKF 1432
+ S+ A + + +A KT + P++ K G
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 1433 TIAPVRQTSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSE 1492
T + +GG ED S + D E+ G+ A + KS
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSE----------ESDSEEEKTGL----AVTVGQAKSV 718
Query: 1493 KQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMA 1552
+ + ASVP + S+G+G + +L T A+KQ+ SE +
Sbjct: 719 GKGLQVKAASVP---VKGSLGQG------TAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 1553 KKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKE 1612
+ A +P + V ++ K + K+ A K +A T
Sbjct: 770 DSEEAAASPAQ-------------VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT-- 814
Query: 1613 PKYEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRS 1672
A A + P K+ + Q T + P SVG Q +E S
Sbjct: 815 ----AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS 870
Query: 1673 STLPAKFQNPVEPIEPV 1689
S + + E + V
Sbjct: 871 SEEESDSEEEAETLAQV 887
Score = 38.9 bits (89), Expect = 0.043
Identities = 83/377 (22%), Positives = 138/377 (36%), Gaps = 53/377 (14%)
Query: 451 PNLDEPLPVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDK 510
P P+ V+ K E+P S EE S + E E M +A + + +T+ K
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKACPK 646
Query: 511 KTTDQAP--------NTDASRSQGYPMS-------AAYGRRWRRKGASVSGLSGCEFKGR 555
KT A T A R G S A G + + +S S S E +
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 556 SL-----KQSSEGYGLGDRAGSSPTNK-----TARNVPFSH----LSLEKDNMEQPTTSQ 601
L + S G GL +A S P TA +P ++ + E +S+
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 602 PETTTPQGLLSDKDDMGRRNAGIDFGSRKASA-AQPIPENMDNSM--VSDPQPYHEDAAS 658
E SD ++ A + +K A A P ++ +S P AA
Sbjct: 767 EE--------SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
+++ ++ + ST SV + + + Q +E D ++ +
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEEE 874
Query: 719 MESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEE 778
+S ++ +T+ + KPSG HQ A++ + KG A PP S+ + ++
Sbjct: 875 SDSEEEAETLAQVKPSGKTHQ-IRAALAPAKESPRKG---AAPTPPGKTGPSAAQAGKQD 930
Query: 779 VSSDSENIPEEGDGSEE 795
DS + EE D E
Sbjct: 931 ---DSGSSSEESDSDGE 944
Score = 36.6 bits (83), Expect = 0.21
Identities = 213/1054 (20%), Positives = 359/1054 (34%), Gaps = 134/1054 (12%)
Query: 460 EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNT 519
E EEE +E K+ + N LG D S +K +TE K T + P+
Sbjct: 86 ESSEEEEEAE--AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK-TGNSMPHP 142
Query: 520 DASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTA 579
++ +S R+ A+ + +S E +G S +G + G +
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-----SVPAFGAAAKPGMVSAGQAD 197
Query: 580 RNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNA------GIDFGSRKASA 633
+ + S ++ ++E + +P + S K+ R+ A G K A
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSV-STKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 634 AQPI-----PENMDNSMVSDPQPYHEDAASGAEKTEARASLSLM------VESLSTTQEE 682
P PE S S+ E+ A +++ +AS ++ + T +
Sbjct: 257 LPPAKRAKKPEEESES--SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 683 AILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFT 742
A + +A + + ++++ S + + S+ E+ + + + K SG Q
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA-AKALLQAKASGKTSQVGA 373
Query: 743 ASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSS 802
AS S KG A PP + K A + DS++ EE D SEE A +
Sbjct: 374 ASAPAKESPR-KG---AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD-SEEEAPAQAK 428
Query: 803 QSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNT 862
S GK +V + S E R A + + + +S S +
Sbjct: 429 PS-GK---APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS------S 478
Query: 863 SDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPT 922
S++ S E L + AQ K+ Q V AS M P + P+
Sbjct: 479 SEESDSDREALAAMNAAQVKPLGKSPQ-VKPAST---------MGMGPLGKGAGPVPPGK 528
Query: 923 VQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLP 982
V P++ VG + S+S E SS V +++ P
Sbjct: 529 VGPATPSAQVGKWEEDSES------------------SSEESSDSSDGEVPTAVA--PAQ 568
Query: 983 PKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEE 1042
K L ++ K + G A + V+ P + +S + SE A
Sbjct: 569 EKSLGN-ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE-APAA 626
Query: 1043 GTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAP------TPSK---YTSPPWVTPK 1093
T + P + Q PK T+ S+ VAP P K TSP +P
Sbjct: 627 MTAAQAKPALKIPQTKACPK-----KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
Query: 1094 FEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGS-- 1151
Q A S++ E D +E + +TVG + + + + A + GS
Sbjct: 682 VAGGTQRPAEDSSSSEESDSEEE----KTGLAVTVG-QAKSVGKGLQVKAASVPVKGSLG 736
Query: 1152 ------------PLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKF 1199
P Q + + S+ E S E+ A K+ + + TQ+
Sbjct: 737 QGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSV--KKTQAKANP 794
Query: 1200 MAQQIFSESSALKRGSDVAPLPPNLPSKSLS--KPEVKH----QVFSDSGSANPKGG--I 1251
A + S + V +S S KP V++ V + ++ P G +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
Query: 1252 SSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVS 1311
++ P + G E+ +E S K L+ A P +
Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
Query: 1312 PVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVP---VKQSSGEKHLPSS 1368
P + P + KQ SS+ SD P + V P + P++
Sbjct: 915 PPGKTGPSA-AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 973
Query: 1369 SPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATK 1428
+P Q Q S+ A A S S+S DE T+ + G + + ++P +
Sbjct: 974 TPAQAQAASTPRKARASESTARSSSSE---SEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1429 PGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNNQ 1462
IAP ++ G S KE DG +
Sbjct: 1031 -----IAP---KASMAGASSSKESSRISDGKKQE 1056
Score = 34.7 bits (78), Expect = 0.82
Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 20/246 (8%)
Query: 177 KKEKEAEDTQEE-EMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFML 235
+K++++E ++EE + E + S + + S + + P ARA S+ G+ + +
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 236 GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAV 295
+RS SK+ P P + S L + + VP V + A Q P
Sbjct: 817 AQAKQRSPSKVKP--------PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED- 867
Query: 296 WVAGPKITENPPSRR-RRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKS-LT 353
+G E+ L+ + P + I L ESP+ P K+ +
Sbjct: 868 --SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK---ESPRKGAAPTPPGKTGPS 922
Query: 354 ATQSFSELSSGPDCSQSLTAFATLASTSSTQL---PIGFSTPATTQGCLDSSAARHKMTL 410
A Q+ + SG +S + A+ +S Q+ P+ F P + ++ A+ +
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 982
Query: 411 NPRKQK 416
PRK +
Sbjct: 983 TPRKAR 988
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 62.4 bits (150), Expect = 4e-09
Identities = 259/1358 (19%), Positives = 449/1358 (33%), Gaps = 210/1358 (15%)
Query: 458 PVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAP 517
P + E N LVSE E+ + P K GM SA + + + D+ + P
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 518 NTDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNK 577
+ ++ + +S RK A G G + +G G+ P K
Sbjct: 217 SVKPAQVKASSVSTKESPA--RKAAPAPGKVG------DVTPQVKG-------GALPPAK 261
Query: 578 TARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGR----RNAGIDFGSRKASA 633
A+ E+++ S+ E P G S + R A
Sbjct: 262 RAKKP-------EEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 634 AQPIPENMDNSMVS---------DPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAI 684
A P P ++ S D + E+++ E+T A +L S T+Q A
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 685 LSVAAE------AQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVH 738
+ A E A + + +A + S ES + + + KPSG
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 739 QTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAH 798
Q AS S KG A PPR ++ + + DS + EE D E
Sbjct: 435 QVRAASAPAKESPR-KG---AAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
Query: 799 GHSSQSLGKFEDEQEVFSESKSFVEDLSSS-------------------EEELDLRCLSQ 839
++ + +V S + L + E D S+
Sbjct: 491 AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSE 550
Query: 840 ALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALG---------KPKNQQE 890
+ D EV T + EK + + + P + P Q G KP + E
Sbjct: 551 ESSDSSDGEVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE 609
Query: 891 VSSASNNTPEEQN-----DFMQQLPS-------RCPSQPIMNPTVQQQVPTSSVGTSIKQ 938
S S+++ + + Q P+ CP + N T +V VGT +
Sbjct: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPR 667
Query: 939 SDSVEPIPP-RHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQ 997
P P + ++ SSS +S + EE + + V +
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA-------KSVGK 720
Query: 998 NMFSGSEDIAVERVIS--VEPLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLS 1055
+ + + V+ + P+LP + ++T + + +S + EE + E +
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE----EAAA 776
Query: 1056 QPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPW-VTPKFEELYQLSAHPESTTVEEDIS 1114
P++ + A ++ AP+ S P V + Q S V +
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1115 KEQLLPRHLSQLTVGNKV----QQLSSNFERAAIEADISGSPLPPQYATQFLKRSKVQEM 1170
L S +VG V Q + E + + S S + Q K ++
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
Query: 1171 TSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLPSKSLS 1230
+ L +P P T +Q S SS+ + SD P + S +
Sbjct: 897 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVI 955
Query: 1231 KPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKE 1290
KP + +F D + +P G P P Q+ P+K + SE SS E
Sbjct: 956 KPPL---IFVDP-NRSPAG-------PAATPAQAQAA-STPRKARA-SESTARSSSSESE 1002
Query: 1291 QLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKG 1350
+Q L P V + + P+ + PK S + SK ++S
Sbjct: 1003 DEDVIPATQCLT-PGIRTNVVTMPTAHPR--------IAPKASMAGASSSKESSRISDGK 1053
Query: 1351 PVNVPVKQ-SSGEKHLPSSSPFQQQVHSSSVNAAARRSVFE---------SNSDNWFLGR 1400
P Q S LP++SP V + N + + E S+ D+
Sbjct: 1054 KQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSD 1113
Query: 1401 DEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQTSTSGGIYSKKEDLESG---- 1456
+ + + + QG+K+ P P+ + + S+ + + + L SG
Sbjct: 1114 SSSGSEEDGEGPQGAKSAHTLGPTPSRT--ETLVEETAAESSEDDVVAPSQSLLSGYMTP 1171
Query: 1457 ----------------DGNNNQHANLSNQDDVE----------------KLFGVRLKRAP 1484
D + + + L+ +DD + K G
Sbjct: 1172 GLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGT 1231
Query: 1485 PSQKYKSEK-------------QDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGN 1531
QK + K Q N TQ P++ + + ++ ++ L
Sbjct: 1232 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1291
Query: 1532 LTKISYVADKQQSRPKSESMAKKQPACKTPGKP------AGQQSDYAVSEPVWITMAKQK 1585
+ + + ++ + ++ QPA +TP AG+ + +VS T +K K
Sbjct: 1292 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1351
Query: 1586 QKSFKAHISVKELKTKSNAGADAETKEPK---------YEGAGSANENQPKKMFTSSVHK 1636
K KA VKE K K + G+ EP+ EG +N K+ S K
Sbjct: 1352 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1411
Query: 1637 QEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSST 1674
++K + K K K+ + K + P+ +K+ K+ T
Sbjct: 1412 KDKEKKEKKKKAKKA----STKDSESPSQKKKKKKKKT 1445
Score = 46.2 bits (108), Expect = 3e-04
Identities = 133/677 (19%), Positives = 227/677 (33%), Gaps = 81/677 (11%)
Query: 1036 ESTAVEEGTYVEP-LPPRCLSQPSERPKFLDSMSTSA-------EWSSPVAPTPSKYTSP 1087
ES + EEG+ E P SQ K L + SA + ++P P + +
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328
Query: 1088 PWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEAD 1147
K EE + S+ S + EE + + LL Q K Q+ + A
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALL-----QAKASGKTSQVGAASAPAKESPR 383
Query: 1148 ISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSE 1207
+P PP + +++ + + + E S + P Q+ A Q+ +
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA----PAQAKPSGKAPQVRAA 439
Query: 1208 SSALKRG--SDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSL 1265
S+ K AP PP + ++ +V Q DS S++ + + L + Q
Sbjct: 440 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALAAMNAAQVK 498
Query: 1266 GRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSK 1325
+ PQ V S G + P ++ A + + +SS + +S
Sbjct: 499 PLGKSPQ-VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
Query: 1326 KQLPPK-------------HSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQ 1372
++P + S +K PQ + GPV V VK EK + +S +
Sbjct: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA--GPVAVQVK---AEKPMDNSESSE 612
Query: 1373 QQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKF 1432
+ S+ A + + +A KT + P++ K G
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 1433 TIAPVRQTSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSE 1492
T + +GG ED S + D E+ G+ A + KS
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSE----------ESDSEEEKTGL----AVTVGQAKSV 718
Query: 1493 KQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMA 1552
+ + ASVP + S+G+G + +L T A+KQ+ SE +
Sbjct: 719 GKGLQVKAASVP---VKGSLGQG------TAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 1553 KKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKE 1612
+ A +P + V ++ K + K+ A K +A T
Sbjct: 770 DSEEAAASPAQ-------------VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT-- 814
Query: 1613 PKYEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRS 1672
A A + P K+ + Q T + P SVG Q +E S
Sbjct: 815 ----AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS 870
Query: 1673 STLPAKFQNPVEPIEPV 1689
S + + E + V
Sbjct: 871 SEEESDSEEEAETLAQV 887
Score = 38.9 bits (89), Expect = 0.043
Identities = 83/377 (22%), Positives = 138/377 (36%), Gaps = 53/377 (14%)
Query: 451 PNLDEPLPVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDK 510
P P+ V+ K E+P S EE S + E E M +A + + +T+ K
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKACPK 646
Query: 511 KTTDQAP--------NTDASRSQGYPMS-------AAYGRRWRRKGASVSGLSGCEFKGR 555
KT A T A R G S A G + + +S S S E +
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 556 SL-----KQSSEGYGLGDRAGSSPTNK-----TARNVPFSH----LSLEKDNMEQPTTSQ 601
L + S G GL +A S P TA +P ++ + E +S+
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 602 PETTTPQGLLSDKDDMGRRNAGIDFGSRKASA-AQPIPENMDNSM--VSDPQPYHEDAAS 658
E SD ++ A + +K A A P ++ +S P AA
Sbjct: 767 EE--------SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
+++ ++ + ST SV + + + Q +E D ++ +
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEEE 874
Query: 719 MESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEE 778
+S ++ +T+ + KPSG HQ A++ + KG A PP S+ + ++
Sbjct: 875 SDSEEEAETLAQVKPSGKTHQ-IRAALAPAKESPRKG---AAPTPPGKTGPSAAQAGKQD 930
Query: 779 VSSDSENIPEEGDGSEE 795
DS + EE D E
Sbjct: 931 ---DSGSSSEESDSDGE 944
Score = 36.6 bits (83), Expect = 0.21
Identities = 213/1054 (20%), Positives = 359/1054 (34%), Gaps = 134/1054 (12%)
Query: 460 EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNT 519
E EEE +E K+ + N LG D S +K +TE K T + P+
Sbjct: 86 ESSEEEEEAE--AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK-TGNSMPHP 142
Query: 520 DASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTA 579
++ +S R+ A+ + +S E +G S +G + G +
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-----SVPAFGAAAKPGMVSAGQAD 197
Query: 580 RNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNA------GIDFGSRKASA 633
+ + S ++ ++E + +P + S K+ R+ A G K A
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSV-STKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 634 AQPI-----PENMDNSMVSDPQPYHEDAASGAEKTEARASLSLM------VESLSTTQEE 682
P PE S S+ E+ A +++ +AS ++ + T +
Sbjct: 257 LPPAKRAKKPEEESES--SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 683 AILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFT 742
A + +A + + ++++ S + + S+ E+ + + + K SG Q
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA-AKALLQAKASGKTSQVGA 373
Query: 743 ASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSS 802
AS S KG A PP + K A + DS++ EE D SEE A +
Sbjct: 374 ASAPAKESPR-KG---AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD-SEEEAPAQAK 428
Query: 803 QSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNT 862
S GK +V + S E R A + + + +S S +
Sbjct: 429 PS-GK---APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS------S 478
Query: 863 SDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPT 922
S++ S E L + AQ K+ Q V AS M P + P+
Sbjct: 479 SEESDSDREALAAMNAAQVKPLGKSPQ-VKPAST---------MGMGPLGKGAGPVPPGK 528
Query: 923 VQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLP 982
V P++ VG + S+S E SS V +++ P
Sbjct: 529 VGPATPSAQVGKWEEDSES------------------SSEESSDSSDGEVPTAVA--PAQ 568
Query: 983 PKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEE 1042
K L ++ K + G A + V+ P + +S + SE A
Sbjct: 569 EKSLGN-ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE-APAA 626
Query: 1043 GTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAP------TPSK---YTSPPWVTPK 1093
T + P + Q PK T+ S+ VAP P K TSP +P
Sbjct: 627 MTAAQAKPALKIPQTKACPK-----KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
Query: 1094 FEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGS-- 1151
Q A S++ E D +E + +TVG + + + + A + GS
Sbjct: 682 VAGGTQRPAEDSSSSEESDSEEE----KTGLAVTVG-QAKSVGKGLQVKAASVPVKGSLG 736
Query: 1152 ------------PLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKF 1199
P Q + + S+ E S E+ A K+ + + TQ+
Sbjct: 737 QGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSV--KKTQAKANP 794
Query: 1200 MAQQIFSESSALKRGSDVAPLPPNLPSKSLS--KPEVKH----QVFSDSGSANPKGG--I 1251
A + S + V +S S KP V++ V + ++ P G +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
Query: 1252 SSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVS 1311
++ P + G E+ +E S K L+ A P +
Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
Query: 1312 PVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVP---VKQSSGEKHLPSS 1368
P + P + KQ SS+ SD P + V P + P++
Sbjct: 915 PPGKTGPSA-AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 973
Query: 1369 SPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATK 1428
+P Q Q S+ A A S S+S DE T+ + G + + ++P +
Sbjct: 974 TPAQAQAASTPRKARASESTARSSSSE---SEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1429 PGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNNQ 1462
IAP ++ G S KE DG +
Sbjct: 1031 -----IAP---KASMAGASSSKESSRISDGKKQE 1056
Score = 34.7 bits (78), Expect = 0.82
Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 20/246 (8%)
Query: 177 KKEKEAEDTQEE-EMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFML 235
+K++++E ++EE + E + S + + S + + P ARA S+ G+ + +
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 236 GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAV 295
+RS SK+ P P + S L + + VP V + A Q P
Sbjct: 817 AQAKQRSPSKVKP--------PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED- 867
Query: 296 WVAGPKITENPPSRR-RRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKS-LT 353
+G E+ L+ + P + I L ESP+ P K+ +
Sbjct: 868 --SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK---ESPRKGAAPTPPGKTGPS 922
Query: 354 ATQSFSELSSGPDCSQSLTAFATLASTSSTQL---PIGFSTPATTQGCLDSSAARHKMTL 410
A Q+ + SG +S + A+ +S Q+ P+ F P + ++ A+ +
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 982
Query: 411 NPRKQK 416
PRK +
Sbjct: 983 TPRKAR 988
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 59.7 bits (143), Expect = 2e-08
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 25/187 (13%)
Query: 1542 QQSRPKS--ESMAKKQPACKTPGKPAGQQSDYAV--SEPVWITMAKQKQKSFKAHISVKE 1597
QQ +P E+ K++P ++ G + V ++P+WIT+A QKQK F+ + +E
Sbjct: 1049 QQEKPSQTPEAGRKEKPMLQSRHSLDGSKLTEKVETAQPLWITLALQKQKGFREQQATRE 1108
Query: 1598 LK------------TKSNAGADAETKEPKYEGAGSANEN---QPKKMFTSSVHKQEKTAQ 1642
+ +K N + AGS +++ +K ++V + E+ Q
Sbjct: 1109 ERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRPETAVSRLERREQ 1168
Query: 1643 MKPPK--PTKSVGFEAQKILQVPAMEKETKRSSTLPAKFQNPVEPIEPVWFSLARKKAKA 1700
+K PT + P +++ TKR ST A PV EP W +LA++KAKA
Sbjct: 1169 LKKANTLPTSVTVEISDSAPPAPLVKEVTKRFSTPDAA---PVS-TEPAWLALAKRKAKA 1224
Query: 1701 WSHMAEI 1707
WS +I
Sbjct: 1225 WSDCPQI 1231
Score = 47.0 bits (110), Expect = 2e-04
Identities = 82/329 (24%), Positives = 138/329 (41%), Gaps = 69/329 (20%)
Query: 222 MGSKALSHDSIFML--GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVS 279
MG++A SHDSIF+ G E E++ M S D G+ +TL + K +
Sbjct: 1 MGTRAFSHDSIFIPDGGAESEQTVQAM--SQDNILGKV-------KTLQQQLGK--NIKF 49
Query: 280 GAMS-GAVLQNVPTSAVWVAGPKITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDES 338
G S A+ N K S L + P+ EI+++ + +S D E+
Sbjct: 50 GQRSPNAIPMN-----------KANSGEASLEEDLFLTSPM---EIVTQQDIVLS-DAEN 94
Query: 339 PKNPQKKALPHKSLTATQSFSELSSGP----DCSQSLTAFATLASTSSTQLPIGFSTPAT 394
+ +L +L S E P + ++ T+ S + +P+ +
Sbjct: 95 KSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESVNLDAIPLAIAR--- 151
Query: 395 TQGCLDSSAARHKMTLNPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLD 454
LD+SAA+HK+ + P+KQ+ + + R L H QG LE S C+ Q P D
Sbjct: 152 ----LDNSAAKHKLAVKPKKQRVSKK--HRRLAQDPQHEQGGLE-SRPCLDQN-GHPGED 203
Query: 455 EPLPVEPKEEEPNLPLVSEEEK-------------------SITKPKEINEKKLGMDSAD 495
+P EEEPN PL SEEE+ + + + E++L + +
Sbjct: 204 KP---TWHEEEPN-PLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRL--QALE 257
Query: 496 SSSQKQNNKTEMYDKKTTDQAPNTDASRS 524
++N + E+ +++ Q P +A R+
Sbjct: 258 RRLWEENRRQELLEEEGEGQEPPLEAERA 286
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 56.2 bits (134), Expect = 3e-07
Identities = 120/591 (20%), Positives = 224/591 (37%), Gaps = 95/591 (16%)
Query: 1112 DISKEQLLPRHLSQLTVG----NKVQQLSSNFERA--AIEADISGSPLPPQYATQFLKRS 1165
D +++P L L +G N++ ++++ F +A A + D + S L Y+ +LK +
Sbjct: 3 DAGIRRVVPSDLYPLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSF-WLKSA 61
Query: 1166 KVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPN-- 1223
KV E K+ G P K A SE S+ + P
Sbjct: 62 KVPE-----RKLQANG----------PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAA 106
Query: 1224 LPSKSLSKPEVKHQV-FSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAP 1282
+P+K + P K S+S S+ + K P+Q +P+ + + +AP
Sbjct: 107 VPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQ------AKAAKAP 160
Query: 1283 GKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKF 1342
K + + S K + + K++PV+ + + + PK ++ + S
Sbjct: 161 PKKAKSSDSDSDSSSEDEPPKNQ-KPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219
Query: 1343 QPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDE 1402
SS + K ++ K + P +Q V + V AA + S+S++ +E
Sbjct: 220 SSSSSSSSDDSEEEKAAATPK---KTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEE 276
Query: 1403 AFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNNQ 1462
+ KK + P S+P P+ P K ++ T K++ +ES + ++++
Sbjct: 277 ----EQKKPMKNKPGPYSSVPPPSAPPPKKSLG----TQPPKKAVEKQQPVESSEDSSDE 328
Query: 1463 HANLSNQDDVEKLFGVRLK---RAPPSQKYKSEKQDNFTQLAS----VPSGPISSSVGRG 1515
+ S ++ V K + PP++K D+ +S PS P ++
Sbjct: 329 SDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSS 388
Query: 1516 HK--IRSTSQGLLDAA-------GNLTKISYVADKQQSRPKSESM--------------- 1551
+K + + S + AA G ++ AD S +S S
Sbjct: 389 NKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPK 448
Query: 1552 AKKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVK--------------- 1596
A + A P K A Q S + S+ + ++++K+ K+ + K
Sbjct: 449 ATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPAS 508
Query: 1597 ------ELKTKSNAGADAETKEPKYEGAGSANENQPKKMFTSSVHKQEKTA 1641
E S++ +E +E K +G GS PK TS++ Q A
Sbjct: 509 AKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKA 559
Score = 37.4 bits (85), Expect = 0.13
Identities = 105/575 (18%), Positives = 206/575 (35%), Gaps = 64/575 (11%)
Query: 858 EKYNTSDDCSSSEEDLPLRHP--------AQALGKPKNQQEV-SSASNNTPEEQNDFMQQ 908
+K ++SD SSEE+ ++ P A+ +G P + +S S+++ E +D ++
Sbjct: 80 KKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEE 139
Query: 909 LPSRCPSQPIMNPTVQ-QQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSP 967
+ P Q + P + + P +S SDS P +P + P + + +P
Sbjct: 140 DQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAP 199
Query: 968 KSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVE-------RVISVEPLLPR 1020
A PK+ + + S S+D E + + + ++ +
Sbjct: 200 PKPA--------RAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAK 251
Query: 1021 YSPQSLTDPQIRQIS--ESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVA 1078
++ T P + S +S++ EE +P+ + S P P A
Sbjct: 252 APVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPP--------------PSA 297
Query: 1079 PTPSKY--TSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLP---RHLSQLTVGNKVQ 1133
P P K T PP E+ + + +S+ + S+E+ P +S+ T
Sbjct: 298 PPPKKSLGTQPP--KKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPA 355
Query: 1134 QLSSNFERAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPI---PR 1190
+ ++ + ++D S P K S + + + K P+ +
Sbjct: 356 KKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQK 415
Query: 1191 RPTQSFVKFMAQQIFSESSALKRGSDVAPLPP--------NLPSKSLSKPEVKHQVFSDS 1242
T+ +++ S S K VA P +LP+K + SDS
Sbjct: 416 LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDS 475
Query: 1243 GSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALR 1302
S+ + +SK K P + G + + +A SS + S + +
Sbjct: 476 SSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKG 535
Query: 1303 KPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGE 1362
K + + +S +N K K+S + + K + SK KQ+
Sbjct: 536 KGSPRPQAPKANGTSALTAQNGK---AAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592
Query: 1363 KHLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWF 1397
K + +P +++ + N +R E + + F
Sbjct: 593 KE--AETPQAKKIKLQTPNTFPKRKKGEKRASSPF 625
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 55.1 bits (131), Expect = 6e-07
Identities = 99/439 (22%), Positives = 166/439 (37%), Gaps = 44/439 (10%)
Query: 495 DSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKG 554
+SS + +K ++ D + +T + G S + +R G G S KG
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSEEGLG---SDDHQYIYRLAG----GFSRSTGKG 98
Query: 555 RSLKQSSEGYGLGDRAG---SSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLL 611
K E D G S P K + S L ++D+ + T E + PQG
Sbjct: 99 GDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDD--TIQASEESAPQGQD 156
Query: 612 SDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTEARASLSL 671
S +D +D R S PE D++ S+ + + S E + S L
Sbjct: 157 SAQDTTSESRE-LDNEDRVDSK----PEGGDSTQESESEEHWVGGGSDGESSHGDGS-EL 210
Query: 672 MVESLSTTQEEAILSVAAEAQVFMNPSHIQLED-----QEAFSFDLQKAQSKMESAQDV- 725
E + + E+I S ++ MN + ++ ++ ++A + D +Q ++ +
Sbjct: 211 DDEGMQSDDPESIRSERGNSR--MNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIF 268
Query: 726 --QTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDS 783
I +E + T + ST PR + + D++E S
Sbjct: 269 RKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQE 328
Query: 784 ENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESK--------SFVEDL--SSSEEELD 833
E+ +G SE + S E ++EV SES+ S+VED S S EE
Sbjct: 329 ESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDS 388
Query: 834 LRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSS 893
LS + E + + +ESS E N S++ S ED + + G + S
Sbjct: 389 SHTLSHSKSESREEQADSESS---ESLNFSEESPESPED---ENSSSQEGLQSHSSSAES 442
Query: 894 ASNNTPEEQNDFMQQLPSR 912
S + E++D Q SR
Sbjct: 443 QSEESHSEEDDSDSQDSSR 461
Score = 40.4 bits (93), Expect = 0.015
Identities = 85/417 (20%), Positives = 144/417 (34%), Gaps = 60/417 (14%)
Query: 462 KEEEPNLPLVSEEEKSITKPKEINEKKLGMDSA-DSSSQKQNNKTEMYDKKTTDQAPNTD 520
++E N L S+E+ T G DSA D++S+ + E + +T
Sbjct: 126 RQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQ 185
Query: 521 ASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTAR 580
S S+ + + G S G G E + QS + + G+S N
Sbjct: 186 ESESEEHWVGGG------SDGESSHG-DGSELDDEGM-QSDDPESIRSERGNSRMNSAGM 237
Query: 581 NVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPEN 640
S + E+ N + SQ ++ SRK I E
Sbjct: 238 KSKESGENSEQANTQDSGGSQL---------------------LEHPSRKIFRKSRISEE 276
Query: 641 MDNSMVSDPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHI 700
D S + D E + E + +R + LS + ++ +++ ++
Sbjct: 277 DDRSELDDNNTMEEVKSDSTENSNSRDT------GLSQPRRDSKGDSQEDSKENLSQEES 330
Query: 701 QLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAK 760
Q D + + S E++ + Q + G+ T+ V + + + +
Sbjct: 331 QNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSH 390
Query: 761 TLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKS 820
TL SR+ A+ SS+S N EE S E + S + L E SE
Sbjct: 391 TLSHSK--SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 448
Query: 821 FVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRH 877
ED S S++ SS E N+++ SSSEED L++
Sbjct: 449 SEEDDSDSQD----------------------SSRSKEDSNSTESKSSSEEDGQLKN 483
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 53.1 bits (126), Expect = 2e-06
Identities = 78/403 (19%), Positives = 149/403 (36%), Gaps = 30/403 (7%)
Query: 472 SEEEKSITKPKEINEKKLGMDSADSS----SQKQNNKTEMYDKKTTDQAPNTDASRSQGY 527
S + + + N+ DS+DSS S ++ ++ D +D + ++D+S S
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 528 PMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHL 587
S+ +S S S G S+ R+ SS ++ ++ + S+
Sbjct: 833 SDSS---------NSSDSSDSSDSSDGSDSDSSN-------RSDSSNSSDSSDSSDSSNS 876
Query: 588 SLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVS 647
S D+ + +S ++ SD D N+ S +S + + DNS S
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936
Query: 648 DPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEA 707
D D++ ++ + + S + S S+ ++ S ++++ + S +
Sbjct: 937 D-SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995
Query: 708 FSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSL 767
S D + +S+ D S N + +S +S ++ + +
Sbjct: 996 DSSDSSNSSDSSDSS-DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054
Query: 768 FQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSS 827
SS D+ + SSDS + + D S+ SS S + S S D S
Sbjct: 1055 SNSSDSSDSSD-SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113
Query: 828 SEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSE 870
S + D D+ ++SS + N+SD SSE
Sbjct: 1114 SSDSSD-------SSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 49.7 bits (117), Expect = 2e-05
Identities = 70/384 (18%), Positives = 143/384 (37%), Gaps = 15/384 (3%)
Query: 492 DSADSS-SQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMSAAYGRRWRRKGASVSGLSGC 550
DS+DSS S + +N ++ D + + ++D+S S S+ +S + S
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 551 EFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGL 610
SS+ D + SS ++ ++ S S D+ + +S ++
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSD----SSDSNSSDSSDSSNSSDSSDSSDSSD 993
Query: 611 LSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTEARASLS 670
SD D + D S+ N +S S D++ ++ +++ S
Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS-- 1051
Query: 671 LMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQ--DVQTI 728
S + + + S ++++ + S + + S D + +S+ D
Sbjct: 1052 ---SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Query: 729 CKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPE 788
S + + +S +S ++ + + +SS D+ + SSDS + +
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD-SSDSSDSSD 1167
Query: 789 EGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPE--D 846
D S+ +SS S + S S D S S + D S + + + D
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227
Query: 847 AEVFTESSSYVEKYNTSDDCSSSE 870
+ ESS + ++SD +SS+
Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSD 1251
Score = 44.3 bits (103), Expect = 0.001
Identities = 73/400 (18%), Positives = 144/400 (36%), Gaps = 16/400 (4%)
Query: 472 SEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNTDASRSQGYPMSA 531
S + KS + + ++ DS+DSS ++ D ++D + ++D+S S S
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD-SDSSDSSDSDSSDSSN 600
Query: 532 AYGRRWRRKGASVSGLS-GCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLE 590
+ + S S + K S K S+ ++ SS +N S
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS----------SDS 650
Query: 591 KDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFG-SRKASAAQPIPENMDNSMVSDP 649
DN + +S ++ SD D + + S +S + E+ D+S SD
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 650 QPYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFS 709
+S + +++ +S S S + + + S ++ + + S + S
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 710 FDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQ 769
D + S+ + S + + + +++ + ++ D + S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS--N 828
Query: 770 SSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSE 829
SS D+ SSDS + + DGS+ + S S + S S + S+E
Sbjct: 829 SSDSSDSSN-SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Query: 830 EELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSS 869
+ D+ + SS + N+SD SS
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Score = 39.7 bits (91), Expect = 0.025
Identities = 67/345 (19%), Positives = 134/345 (38%), Gaps = 20/345 (5%)
Query: 492 DSADSSSQKQNNKTEMYDKK-TTDQAPNTDASRSQGYPMSAAYGRRWRRKGASVSGLSGC 550
DS++SS +N ++ D ++D + ++D+S S S+ +S S S
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 551 EFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGL 610
SS+ D + SS ++ ++ + S+ S D+ + +S +
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS----- 1075
Query: 611 LSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTEARASLS 670
SD D + D S +S + ++ D+S SD + + S + +S S
Sbjct: 1076 -SDSSDSSESSDSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 671 LMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQ--DVQTI 728
S + + + S ++++ + S + S D + + +S+ D
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 729 CKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPE 788
S + + +S +S ++ + + +SS D+ + SSDS N +
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD-SSDSSNSSD 1251
Query: 789 EGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELD 833
D S+ SS S DE + S+SKS + + S+ + D
Sbjct: 1252 SSDSSD------SSDSTSDSNDESD--SQSKSGNGNNNGSDSDSD 1288
Score = 36.2 bits (82), Expect = 0.28
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 4/134 (2%)
Query: 770 SSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSE 829
SS D+ + SSDS + + D S+ + S+S D + S+S S D S +
Sbjct: 598 SSNSSDSSD-SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS--SDSSDNS 654
Query: 830 EELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQ 889
+ D S + + D+ ++SSS + N+SD SS+ + +
Sbjct: 655 DSSDSSNSSNS-SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 890 EVSSASNNTPEEQN 903
+ S +SN+ + +
Sbjct: 714 DSSDSSNSNSSDSD 727
Score = 33.5 bits (75), Expect = 1.8
Identities = 29/134 (21%), Positives = 52/134 (38%), Gaps = 4/134 (2%)
Query: 770 SSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSE 829
SS D++ SS SE+ + D + + +SS S + S + S D S S
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675
Query: 830 EELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQ 889
+ S D+ ++SS+ E ++SD S D + + +
Sbjct: 676 DSSS----SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 890 EVSSASNNTPEEQN 903
SS S+N+ + +
Sbjct: 732 SDSSDSSNSSDSSD 745
Score = 33.1 bits (74), Expect = 2.4
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 7/136 (5%)
Query: 770 SSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSE 829
S ++ SSDS N + D S+ SS S D + S+S+S D S
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS----SDSKSDSSKSESDSSDSDSKS 640
Query: 830 EELDLRCL-SQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQ 888
+ D S + D+ + SS + ++SD SSS D + N
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS--DSSNSSDSSDSSDSSNS 698
Query: 889 QEVSSASNNTPEEQND 904
E S +S+++ + +D
Sbjct: 699 SESSDSSDSSDSDSSD 714
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 53.1 bits (126), Expect = 2e-06
Identities = 148/705 (20%), Positives = 252/705 (35%), Gaps = 95/705 (13%)
Query: 843 EPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPE-- 900
+ E F+ES V + D S+ ++ L+H + E A+N+ E
Sbjct: 152 DKEQQTYFSESEIVV--ISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIG 209
Query: 901 ----EQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPR-HPFQPWV 955
+ F Q+ P + VP G+++K+ S E PP F +
Sbjct: 210 QKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKI 269
Query: 956 NPKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVE 1015
P + +E ++ + EE+ + P ++ + + E + V+
Sbjct: 270 QPPLVEEATAKAEPRPAEET------------HVQVQPSTEETPDAEAATAVAENSVKVQ 317
Query: 1016 PLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSS 1075
P +P +I+ S + E LPP PSE P + + AE S
Sbjct: 318 PPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPP-AEILPPPAEKSP 376
Query: 1076 PV-----APTPSKYTSPPWVTPKFEE--LYQLSAHPESTTVEEDISKEQ-LLP------- 1120
V +PS +P V P E L + A E TVEE ++ Q LLP
Sbjct: 377 SVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREE 436
Query: 1121 -RHLSQLT-VGNKVQQLSSNF----------ERAAIEADISGSPLPPQYATQFLKRSKVQ 1168
R L T + ++ + F E A+ E + + PP T RS +
Sbjct: 437 ARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLS 496
Query: 1169 EMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLP-SK 1227
E TS E A +SP+ T Q + +A++ +D P P S+
Sbjct: 497 EETSAEEAHA----EVQSPLAEETTAEEASAEIQLL----AAIEAPADETPAEAQSPLSE 548
Query: 1228 SLSKPEVKHQVFSDSGSANPKG-GISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCS 1286
S E +V S S KG I L ++ P E+
Sbjct: 549 ETSAEEAPAEVQSPSA----KGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAE 604
Query: 1287 SFKEQLSPRQLSQA---LRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQ 1343
++ P +A ++ P E+ + V P E ++ Q PP + A + Q
Sbjct: 605 EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ-PPPAEEAPAEVQPPPAEEAPA----EVQ 659
Query: 1344 PQMSSKGPVNV---PVKQSSGE-KHLPS-SSPFQQ---QVHSSSV-NAAARRSVFESNSD 1394
P + + P V P +++ E + LP+ +P ++ VHS + A + + +S
Sbjct: 660 PPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSP 719
Query: 1395 NWFLGRDEAFAIKTKKFSQGSKNPIKSIPAP-------ATKPGKFTIAPVRQTSTSGGIY 1447
L E F I + ++ S P + P +T+ +A + +
Sbjct: 720 PADLLLTEEFPI-GEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVL 778
Query: 1448 SKKEDLESGDGNNNQHANLSNQDD-------VEKLFGVRLKRAPP 1485
+ E N+ +LSN +D +E +F + LK+ PP
Sbjct: 779 EGEAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQRPP 823
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 52.8 bits (125), Expect = 3e-06
Identities = 105/454 (23%), Positives = 175/454 (38%), Gaps = 51/454 (11%)
Query: 490 GMDSADSSSQKQNNKTEMYD--KKTTDQAPN--------TDASRSQGYPMSAAYGRRWRR 539
G+ A ++ QNN++E + K QAP +D+++S+ S + +R
Sbjct: 12 GLSCALPVTRYQNNESEDSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRL 71
Query: 540 KGASVSGLSGCEFKGRSLKQSSEGYGLGDRAG---SSPTNKTARNVPFSHLSLEKDNMEQ 596
G G S KG K E D G S P K + S L ++D+ +
Sbjct: 72 AG----GFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDD- 126
Query: 597 PTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDA 656
T E + PQG S +D +D R S PE D++ S+ + +
Sbjct: 127 -TIQASEESAPQGQDSAQDTTSESRE-LDNEDRVDSK----PEGGDSTQESESEEHWVGG 180
Query: 657 ASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLED-----QEAFSFD 711
S E + S L E + + E+I S ++ MN + ++ ++ ++A + D
Sbjct: 181 GSDGESSHGDGS-ELDDEGMQSDDPESIRSERGNSR--MNSAGMKSKESGENSEQANTQD 237
Query: 712 LQKAQSKMESAQDV---QTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLF 768
+Q ++ + I +E + T + ST PR
Sbjct: 238 SGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 297
Query: 769 QSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESK--------S 820
+ + D++E S E+ +G SE + S E ++EV SES+ S
Sbjct: 298 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTS 357
Query: 821 FVEDL--SSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHP 878
+VED S S EE LS + E + + +ESS E N S++ S ED +
Sbjct: 358 YVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS---ESLNFSEESPESPED---ENS 411
Query: 879 AQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSR 912
+ G + S S + E++D Q SR
Sbjct: 412 SSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSR 445
Score = 40.4 bits (93), Expect = 0.015
Identities = 85/417 (20%), Positives = 144/417 (34%), Gaps = 60/417 (14%)
Query: 462 KEEEPNLPLVSEEEKSITKPKEINEKKLGMDSA-DSSSQKQNNKTEMYDKKTTDQAPNTD 520
++E N L S+E+ T G DSA D++S+ + E + +T
Sbjct: 110 RQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQ 169
Query: 521 ASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTAR 580
S S+ + + G S G G E + QS + + G+S N
Sbjct: 170 ESESEEHWVGGG------SDGESSHG-DGSELDDEGM-QSDDPESIRSERGNSRMNSAGM 221
Query: 581 NVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPEN 640
S + E+ N + SQ ++ SRK I E
Sbjct: 222 KSKESGENSEQANTQDSGGSQL---------------------LEHPSRKIFRKSRISEE 260
Query: 641 MDNSMVSDPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHI 700
D S + D E + E + +R + LS + ++ +++ ++
Sbjct: 261 DDRSELDDNNTMEEVKSDSTENSNSRDT------GLSQPRRDSKGDSQEDSKENLSQEES 314
Query: 701 QLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAK 760
Q D + + S E++ + Q + G+ T+ V + + + +
Sbjct: 315 QNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSH 374
Query: 761 TLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKS 820
TL SR+ A+ SS+S N EE S E + S + L E SE
Sbjct: 375 TLSHSK--SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 432
Query: 821 FVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRH 877
ED S S++ SS E N+++ SSSEED L++
Sbjct: 433 SEEDDSDSQD----------------------SSRSKEDSNSTESKSSSEEDGQLKN 467
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 52.8 bits (125), Expect = 3e-06
Identities = 93/416 (22%), Positives = 157/416 (37%), Gaps = 58/416 (13%)
Query: 1302 RKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSG 1361
R+ + +K VS S + R K +S +S S S G + SS
Sbjct: 520 RRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSY 579
Query: 1362 EKHLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTK------KFSQGS 1415
+ SS HSS + +R F S+ +I+TK G
Sbjct: 580 SSYSSRSSR-----HSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGE 634
Query: 1416 KNPIKSIPAPATKPGKFTIAPVRQTSTSGGIYSKKEDLE-------------SGDGNNNQ 1462
K+ K P PA T APV + + G + SG G+ +
Sbjct: 635 KSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSS 694
Query: 1463 HANLSNQD---DVEKLFGVRLKRAPPSQKYKSEKQDNFTQLASVPSGPISSSVGRGHKIR 1519
++ S++ V + V + S + + +D + LAS P+SS+ R
Sbjct: 695 YSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLAS----PVSSASSRSPAPA 750
Query: 1520 STSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKTPGKPAGQQSDYAVSEPVWI 1579
T + G K V ++++ R S QP K+ PAG +S S P
Sbjct: 751 QTRK----EKGKSKKEDGVKEEKRKRDSS-----TQPP-KSAKPPAGGKSSQQPSTPQQA 800
Query: 1580 TMAKQKQKSFKAHISVKELK-TKSNAGADAETKEPKYEGAGSANENQP--KKMFTS---S 1633
+ +Q +F AH KE+K T N AD +++ +YE + ++ P K+ TS
Sbjct: 801 PPGQPQQGTFVAH---KEIKLTLLNKAADKGSRK-RYEPSDKDRQSPPPAKRPNTSPDRG 856
Query: 1634 VHKQEKTAQMKPPKP-------TKSVGFEAQKILQVPAMEKETKRSSTLPAKFQNP 1682
++ ++ PKP +K+ A + Q+ K + + +++P K +P
Sbjct: 857 SRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDP 912
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.4 bits (124), Expect = 4e-06
Identities = 213/1103 (19%), Positives = 390/1103 (35%), Gaps = 170/1103 (15%)
Query: 175 VKKKEKEAEDTQEEEMLE-----LSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSH 229
VKK+E+E + E+ +LE LS+ +++ Q E++ K +A + K L
Sbjct: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
Query: 230 DSIFMLGPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQN 289
+ + E RS K P ++ ++ P+ + + LP+ ++ P + + +Q
Sbjct: 1217 EKKLIPEEEKIRSEEKK-PLLEEKKPTPEDK----KLLPEAKTSAPEEQKHDLLKSQVQI 1271
Query: 290 VPTSAVWVAGPKITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPH 349
PK + + ++ +P P+ + K DD++ K +++ P
Sbjct: 1272 AEEKLEGRVAPKTVQEGKQPQTKMEGLPSGT-PQSLPKE------DDKTTKTIKEQPQP- 1323
Query: 350 KSLTATQSFSELSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAAR---- 405
T ++ G + ++ + +S+ + P G S + + SS
Sbjct: 1324 ---PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
Query: 406 ----HKMTLNPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLD------E 455
K L K+ Q P + + + L+ TL + E
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE 1440
Query: 456 PLPVEPKEEEPNLPLVSEEEKSITKP--KEINEKKLGMDSADS-----SSQKQNNKTEMY 508
P +PK++E L E +I++ KE E++ DS SS+ K+E
Sbjct: 1441 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV 1500
Query: 509 DKKTTDQAPN---TDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYG 565
D TT + P ++S S+ P+ R++ SV S E+K + G
Sbjct: 1501 DDITTRREPYDSVEESSESENSPVPQ------RKRRTSVGSSSSDEYK------QEDSQG 1548
Query: 566 LGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGID 625
G+ + E D + + ++T + G+ AG
Sbjct: 1549 SGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAG-- 1606
Query: 626 FGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAIL 685
+ + ++D + ED + E E + E+ S EE ++
Sbjct: 1607 ---KHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYR-----ETKSQESEELVV 1658
Query: 686 SVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASV 745
+ + F I+L A + + +Q K D E+P
Sbjct: 1659 TGGGGLRRFKT---IELNSTIADKYSAESSQKKTSLYFD------EEPE----------- 1698
Query: 746 LGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSL 805
L M S T + ++ SL SS P S S + E+ D S G S Q
Sbjct: 1699 LEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSS--LDEDSDSSPSHKKGESKQ-- 1754
Query: 806 GKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDD 865
+ + +ED S EE L E E+ E +E+
Sbjct: 1755 -QRKARHRPHGPLLPTIEDSSEEEE----------LREEEELLKEQEKQREIEQQQRKSS 1803
Query: 866 CSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQ 925
S++D + +PK + SN +P E P++ + +
Sbjct: 1804 SKKSKKDKDELRAQRRRERPK-----TPPSNLSPIE---------DASPTEELRQAAEME 1849
Query: 926 QVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAV-----EESISMKP 980
++ SS + S S+E P P +V Q+V P ++++ E+SI K
Sbjct: 1850 ELHRSSCS---EYSPSIESDPEGFEISPEKIIEV-QKVYKLPTAVSLYSPTDEQSIMQKE 1905
Query: 981 LPPKLL------CQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQI 1034
K L + +M+ + F + + + V EPL Y + D I
Sbjct: 1906 GSQKALKSAEEMYEEMMHKTHKYKAFPAANE--RDEVFEKEPL---YGGMLIED----YI 1956
Query: 1035 SESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSP-PWVTPK 1093
ES + E TY + L++ E F+ + + + Y P +T
Sbjct: 1957 YES--LVEDTYNGSVDGSLLTRQEEENGFMQQKGREQK----IRLSEQIYEDPMQKITDL 2010
Query: 1094 FEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSPL 1153
+E Y+L + E+ +S ++P + +G V S+ ER ++AD
Sbjct: 2011 QKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGTMV--TSTEEERKLLDAD------ 2062
Query: 1154 PPQYATQFLKRSKVQEMTSRLEKMAVEGTS-NKSPIPRRPTQSFVKFMAQQIFSESSALK 1212
+ +E+ R + G+S ++PI T+S + F S +S++
Sbjct: 2063 -----------AAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVL 2111
Query: 1213 RGSDVAPLPPNLPSKSLSKPEVK 1235
G A L + S +LS P+VK
Sbjct: 2112 SG---ASLTDSTSSATLSIPDVK 2131
Score = 44.3 bits (103), Expect = 0.001
Identities = 105/481 (21%), Positives = 165/481 (34%), Gaps = 85/481 (17%)
Query: 1214 GSDVAPLP----------PNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQ 1263
G D+AP+P P + ++SK + Q S A PK +S P K P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP-- 704
Query: 1264 SLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRN 1323
L + S + P + S + P++ S EQ +PV+ PK+ +
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS-----EQDKAPVADDKPKQPKM 759
Query: 1324 SKKQLPPKHSSQASDR-----SKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSS 1378
K SS A+ + SK Q Q K + + + P + S
Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK 819
Query: 1379 SVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKP-GKFTIAPV 1437
++ A S S+ + + +K + K K P P KP K + P
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
Query: 1438 RQTSTSGG-IYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDN 1496
T+G + + ++ + + + NL + D AP SQ
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD-----------APKSQP-------- 920
Query: 1497 FTQLASVPSGPISSSV-GRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQ 1555
+ P ++ + G G I S + L+ AG Q P S+S
Sbjct: 921 -----TTPQETVTGKLFGFGASIFSQASNLISTAG------------QPGPHSQS----- 958
Query: 1556 PACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKY 1615
PG P Q A S+P + K K + K ETK P
Sbjct: 959 ----GPGAPMKQAP--APSQPP-TSQGPPKSTGQAPPAPAKSIPVKK------ETKAP-- 1003
Query: 1616 EGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTL 1675
+A + +PK +V + E + P K +KS+ E QK + +EK K ST
Sbjct: 1004 ----AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTC 1059
Query: 1676 P 1676
P
Sbjct: 1060 P 1060
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.4 bits (124), Expect = 4e-06
Identities = 213/1103 (19%), Positives = 390/1103 (35%), Gaps = 170/1103 (15%)
Query: 175 VKKKEKEAEDTQEEEMLE-----LSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSH 229
VKK+E+E + E+ +LE LS+ +++ Q E++ K +A + K L
Sbjct: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
Query: 230 DSIFMLGPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQN 289
+ + E RS K P ++ ++ P+ + + LP+ ++ P + + +Q
Sbjct: 1217 EKKLIPEEEKIRSEEKK-PLLEEKKPTPEDK----KLLPEAKTSAPEEQKHDLLKSQVQI 1271
Query: 290 VPTSAVWVAGPKITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPH 349
PK + + ++ +P P+ + K DD++ K +++ P
Sbjct: 1272 AEEKLEGRVAPKTVQEGKQPQTKMEGLPSGT-PQSLPKE------DDKTTKTIKEQPQP- 1323
Query: 350 KSLTATQSFSELSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAAR---- 405
T ++ G + ++ + +S+ + P G S + + SS
Sbjct: 1324 ---PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
Query: 406 ----HKMTLNPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLD------E 455
K L K+ Q P + + + L+ TL + E
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE 1440
Query: 456 PLPVEPKEEEPNLPLVSEEEKSITKP--KEINEKKLGMDSADS-----SSQKQNNKTEMY 508
P +PK++E L E +I++ KE E++ DS SS+ K+E
Sbjct: 1441 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV 1500
Query: 509 DKKTTDQAPN---TDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYG 565
D TT + P ++S S+ P+ R++ SV S E+K + G
Sbjct: 1501 DDITTRREPYDSVEESSESENSPVPQ------RKRRTSVGSSSSDEYK------QEDSQG 1548
Query: 566 LGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGID 625
G+ + E D + + ++T + G+ AG
Sbjct: 1549 SGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAG-- 1606
Query: 626 FGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTEARASLSLMVESLSTTQEEAIL 685
+ + ++D + ED + E E + E+ S EE ++
Sbjct: 1607 ---KHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYR-----ETKSQESEELVV 1658
Query: 686 SVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASV 745
+ + F I+L A + + +Q K D E+P
Sbjct: 1659 TGGGGLRRFKT---IELNSTIADKYSAESSQKKTSLYFD------EEPE----------- 1698
Query: 746 LGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSL 805
L M S T + ++ SL SS P S S + E+ D S G S Q
Sbjct: 1699 LEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSS--LDEDSDSSPSHKKGESKQ-- 1754
Query: 806 GKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDD 865
+ + +ED S EE L E E+ E +E+
Sbjct: 1755 -QRKARHRPHGPLLPTIEDSSEEEE----------LREEEELLKEQEKQREIEQQQRKSS 1803
Query: 866 CSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQ 925
S++D + +PK + SN +P E P++ + +
Sbjct: 1804 SKKSKKDKDELRAQRRRERPK-----TPPSNLSPIE---------DASPTEELRQAAEME 1849
Query: 926 QVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAV-----EESISMKP 980
++ SS + S S+E P P +V Q+V P ++++ E+SI K
Sbjct: 1850 ELHRSSCS---EYSPSIESDPEGFEISPEKIIEV-QKVYKLPTAVSLYSPTDEQSIMQKE 1905
Query: 981 LPPKLL------CQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQI 1034
K L + +M+ + F + + + V EPL Y + D I
Sbjct: 1906 GSQKALKSAEEMYEEMMHKTHKYKAFPAANE--RDEVFEKEPL---YGGMLIED----YI 1956
Query: 1035 SESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSP-PWVTPK 1093
ES + E TY + L++ E F+ + + + Y P +T
Sbjct: 1957 YES--LVEDTYNGSVDGSLLTRQEEENGFMQQKGREQK----IRLSEQIYEDPMQKITDL 2010
Query: 1094 FEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSPL 1153
+E Y+L + E+ +S ++P + +G V S+ ER ++AD
Sbjct: 2011 QKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGTMV--TSTEEERKLLDAD------ 2062
Query: 1154 PPQYATQFLKRSKVQEMTSRLEKMAVEGTS-NKSPIPRRPTQSFVKFMAQQIFSESSALK 1212
+ +E+ R + G+S ++PI T+S + F S +S++
Sbjct: 2063 -----------AAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVL 2111
Query: 1213 RGSDVAPLPPNLPSKSLSKPEVK 1235
G A L + S +LS P+VK
Sbjct: 2112 SG---ASLTDSTSSATLSIPDVK 2131
Score = 44.3 bits (103), Expect = 0.001
Identities = 105/481 (21%), Positives = 165/481 (34%), Gaps = 85/481 (17%)
Query: 1214 GSDVAPLP----------PNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQ 1263
G D+AP+P P + ++SK + Q S A PK +S P K P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP-- 704
Query: 1264 SLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRN 1323
L + S + P + S + P++ S EQ +PV+ PK+ +
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS-----EQDKAPVADDKPKQPKM 759
Query: 1324 SKKQLPPKHSSQASDR-----SKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSS 1378
K SS A+ + SK Q Q K + + + P + S
Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK 819
Query: 1379 SVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKP-GKFTIAPV 1437
++ A S S+ + + +K + K K P P KP K + P
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
Query: 1438 RQTSTSGG-IYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDN 1496
T+G + + ++ + + + NL + D AP SQ
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD-----------APKSQP-------- 920
Query: 1497 FTQLASVPSGPISSSV-GRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQ 1555
+ P ++ + G G I S + L+ AG Q P S+S
Sbjct: 921 -----TTPQETVTGKLFGFGASIFSQASNLISTAG------------QPGPHSQS----- 958
Query: 1556 PACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKY 1615
PG P Q A S+P + K K + K ETK P
Sbjct: 959 ----GPGAPMKQAP--APSQPP-TSQGPPKSTGQAPPAPAKSIPVKK------ETKAP-- 1003
Query: 1616 EGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRSSTL 1675
+A + +PK +V + E + P K +KS+ E QK + +EK K ST
Sbjct: 1004 ----AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTC 1059
Query: 1676 P 1676
P
Sbjct: 1060 P 1060
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sapiens]
Length = 887
Score = 49.3 bits (116), Expect = 3e-05
Identities = 103/456 (22%), Positives = 163/456 (35%), Gaps = 55/456 (12%)
Query: 1220 LPPNLPSKSLSKPEVKHQVFSDSGSANPKGG---ISSKMLPMKHPLQSLGRPEDPQKVFS 1276
L P LP ++ + E +H+ +G A P+ G +S + P P +K
Sbjct: 380 LTPLLPKSTIQEQE-RHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKP 438
Query: 1277 YSERAPGKCSSFKEQLSPRQL-SQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQ 1335
+ P K S+ K + P L Q P+S +S PPK +
Sbjct: 439 LATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS-----GLVPAAPPKRPAV 493
Query: 1336 ASDRSKFQPQMSSK----GPVNVPVKQSSGEKHLPSSSPFQQ------QVHSSSVNAAAR 1385
AS R P K P K++S K P+S+P + Q + + AAA
Sbjct: 494 ASARPSILPSKDVKPKPIADAKAPEKRASPSK--PASAPASRSGSKSTQTVAKTTTAAAV 551
Query: 1386 RSVFESNSDNWFLGRDEAFAIKTK-KFSQGSKNPIKSIPAPATKPGKFTIAPVRQTSTSG 1444
S S+ L + AIKT+ K ++ K KS+PA ++P + + +++T+T
Sbjct: 552 ASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLS 611
Query: 1445 GIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQLASVP 1504
G + S + S ++K P+ S ++LA+
Sbjct: 612 GTAPAAGVVPSRVKATPMPSRPSTTPFIDK---------KPTSAKPSSTTPRLSRLATNT 662
Query: 1505 SGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPACKTPGKP 1564
S P +V K+ ST G K+ KK A T KP
Sbjct: 663 SAPDLKNV--RSKVGSTENIKHQPGGGRAKVE----------------KKTEAAATTRKP 704
Query: 1565 AGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKEPKYEGAGSANEN 1624
AV++ + QKQ + K I K++ K+ G +
Sbjct: 705 ESN----AVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQI 760
Query: 1625 QPKKMFTSSV-HKQEKTAQMKPPKPTKSVGFEAQKI 1659
Q KK+ S V K A +K V E+QK+
Sbjct: 761 QNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKL 796
Score = 37.0 bits (84), Expect = 0.16
Identities = 163/755 (21%), Positives = 267/755 (35%), Gaps = 129/755 (17%)
Query: 795 ELAHGH-------SSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDA 847
ELA GH QSL E +++ +F EE + + S A++ P+
Sbjct: 176 ELAKGHLLPGVPVEDQSLPGEARALEGYADRGNF--PAHPVNEEKETKEGSVAVQIPDLL 233
Query: 848 EVFTESSSYVEKYNTSD------DCSSSEEDLPLRHPAQALGKPKNQQ------EVSSAS 895
E + S+ E N D D + + DL L P K K E+ S S
Sbjct: 234 EDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVS 293
Query: 896 NNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQ-SDSVEPIPPR-----H 949
TPE Q+DF+ PS+ + + V + T+S G + + D + P +
Sbjct: 294 LPTPEIQSDFLHSKVEAPPSE-VADTLV---IMTASKGVRLPEPKDKILETPQKMTEKSE 349
Query: 950 PFQPWVNPKVEQEVSSSPKS--MAVEESISMKPLPPKLLCQP-----------LMNPKVQ 996
P K ++ + P M +S + PL PK Q + P+
Sbjct: 350 SKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEG 409
Query: 997 QNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEEGT------------ 1044
+ + SG+ + P P + L Q + S S A + T
Sbjct: 410 RPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIG 469
Query: 1045 ------------YVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPV--APTPSKYTSP--P 1088
V PP+ + S RP L S + P+ A P K SP P
Sbjct: 470 GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK---PIADAKAPEKRASPSKP 526
Query: 1089 WVTPKFEELYQLSAHPESTTVEEDI--------SKEQLLPRHLSQLTVGNKVQQLSSNFE 1140
P + + TT + S LLP+ + + K ++
Sbjct: 527 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEV-KKMT 585
Query: 1141 RAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRP-TQSFV-- 1197
++ AD+S P +T +K++ T+ + V +P+P RP T F+
Sbjct: 586 AKSVPADLS---RPKSTSTSSMKKTTTLSGTAPAAGV-VPSRVKATPMPSRPSTTPFIDK 641
Query: 1198 KFMAQQIFSESSALKR--GSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKM 1255
K + + S + L R + AP N+ SK S +KHQ GG +K+
Sbjct: 642 KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ----------PGGGRAKV 691
Query: 1256 LPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSA 1315
+ +PE + + G +S ++Q P Q + K KVS
Sbjct: 692 EKKTEAAATTRKPES-----NAVTKTAGPIASAQKQ--PAGKVQIVSK-----KVSYSHI 739
Query: 1316 SSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQV 1375
S +++ K +P + Q ++ ++SSK + KH P ++
Sbjct: 740 QSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSK------CGSKANIKHKPGGG--DVKI 791
Query: 1376 HSSSVNAAARRSVFESNSDNWFLGRDEA-FAIKTKKFSQGSKNPIKSIPAPATKPGKFTI 1434
S +N + + DN +G A A+KT+ GS+ P+ P +P
Sbjct: 792 ESQKLNFKEKAQAKVGSLDN--VGHLPAGGAVKTE--GGGSEAPLCPGPPAGEEPAISEA 847
Query: 1435 APVRQTSTSGGIYSKKEDLESGDGNNNQHANLSNQ 1469
AP TS + L SG G+ + L +Q
Sbjct: 848 APEAGAPTSASGLNGHPTL-SGGGDQREAQTLDSQ 881
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 47.8 bits (112), Expect = 9e-05
Identities = 97/466 (20%), Positives = 161/466 (34%), Gaps = 71/466 (15%)
Query: 541 GASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTS 600
G + S G + +GR K S++ G DRA + VP + L+LE + S
Sbjct: 2318 GTAGSEEPGAKARGRGRKPSAKAKG--DRAATLEEGNPTDEVPSTPLALEPSSTPGSKKS 2375
Query: 601 QPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGA 660
PE + + KA A P P + S P P E A
Sbjct: 2376 PPEPVDKRAK-----------------APKARPAPPQPSPAPPAFTSCPAP--EPFAELP 2416
Query: 661 EKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQS-KM 719
+ A L+ ++ T+ + + AAE P E + D + S K
Sbjct: 2417 APATSLAPAPLI--TMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKS 2474
Query: 720 ESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTA-------------KGDVYAKTLPPRS 766
+ A++ + ++ +G + + LG A GD+ A+ P
Sbjct: 2475 KKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDL-AQEPGPGL 2533
Query: 767 LFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLS 826
F+ S P + + + ++ EE + S + G SS S S S S E
Sbjct: 2534 TFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSS--------SSSGSETEGEE 2585
Query: 827 SSEEELD-------LRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPA 879
++ D C + + A + SSS ++S SSS +
Sbjct: 2586 EGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
Query: 880 QALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQ------PIMNPTVQQQVPTS--- 930
+ + SS+S+++ + S C S P P+ Q +PT
Sbjct: 2646 SSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK 2705
Query: 931 -------SVGTSIKQSDSVEP-IPPRHPFQPWVNPKVEQEVSSSPK 968
S + K++ + +P PP P QP + PK + S PK
Sbjct: 2706 QAGKARPSAHSPGKKTPAPQPQAPPPQPTQP-LQPKAQAGAKSRPK 2750
Score = 31.6 bits (70), Expect = 6.9
Identities = 33/122 (27%), Positives = 45/122 (36%), Gaps = 6/122 (4%)
Query: 1324 SKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSVNAA 1383
S + P SS +S S SS + SS SSS SSS +++
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
Query: 1384 ARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIP------APATKPGKFTIAPV 1437
+ S ++ D+ DEA T S + P K+ A PGK T AP
Sbjct: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQ 2725
Query: 1438 RQ 1439
Q
Sbjct: 2726 PQ 2727
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 46.2 bits (108), Expect = 3e-04
Identities = 133/677 (19%), Positives = 227/677 (33%), Gaps = 81/677 (11%)
Query: 1036 ESTAVEEGTYVEP-LPPRCLSQPSERPKFLDSMSTSA-------EWSSPVAPTPSKYTSP 1087
ES + EEG+ E P SQ K L + SA + ++P P + +
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328
Query: 1088 PWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEAD 1147
K EE + S+ S + EE + + LL Q K Q+ + A
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALL-----QAKASGKTSQVGAASAPAKESPR 383
Query: 1148 ISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSE 1207
+P PP + +++ + + + E S + P Q+ A Q+ +
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA----PAQAKPSGKAPQVRAA 439
Query: 1208 SSALKRG--SDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSL 1265
S+ K AP PP + ++ +V Q DS S++ + + L + Q
Sbjct: 440 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALAAMNAAQVK 498
Query: 1266 GRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSK 1325
+ PQ V S G + P ++ A + + +SS + +S
Sbjct: 499 PLGKSPQ-VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
Query: 1326 KQLPPK-------------HSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQ 1372
++P + S +K PQ + GPV V VK EK + +S +
Sbjct: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA--GPVAVQVK---AEKPMDNSESSE 612
Query: 1373 QQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKF 1432
+ S+ A + + +A KT + P++ K G
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 1433 TIAPVRQTSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSE 1492
T + +GG ED S + D E+ G+ A + KS
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSE----------ESDSEEEKTGL----AVTVGQAKSV 718
Query: 1493 KQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMA 1552
+ + ASVP + S+G+G + +L T A+KQ+ SE +
Sbjct: 719 GKGLQVKAASVP---VKGSLGQG------TAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 1553 KKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETKE 1612
+ A +P + V ++ K + K+ A K +A T
Sbjct: 770 DSEEAAASPAQ-------------VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT-- 814
Query: 1613 PKYEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQKILQVPAMEKETKRS 1672
A A + P K+ + Q T + P SVG Q +E S
Sbjct: 815 ----AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS 870
Query: 1673 STLPAKFQNPVEPIEPV 1689
S + + E + V
Sbjct: 871 SEEESDSEEEAETLAQV 887
Score = 39.7 bits (91), Expect = 0.025
Identities = 81/386 (20%), Positives = 142/386 (36%), Gaps = 49/386 (12%)
Query: 451 PNLDEPLPVEPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDK 510
P P+ V+ K E+P S EE S + E E M +A + + +T+ K
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKACPK 646
Query: 511 KTTDQAP--------NTDASRSQGYPMS-------AAYGRRWRRKGASVSGLSGCEFKGR 555
KT A T A R G S A G + + +S S S E +
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 556 SL-----KQSSEGYGLGDRAGSSPTNK-----TARNVPFSH----LSLEKDNMEQPTTSQ 601
L + S G GL +A S P TA +P ++ + E +S+
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 602 PETTTPQGLLSDKDDMGRRNAGIDFGSRKASA-AQPIPENMDNSM--VSDPQPYHEDAAS 658
E SD ++ A + +K A A P ++ +S P AA
Sbjct: 767 EE--------SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
+++ ++ + ST SV + + + Q +E D ++ +
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEEE 874
Query: 719 MESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEE 778
+S ++ +T+ + KPSG HQ A++ + KG A T P ++ +++ ++
Sbjct: 875 SDSEEEAETLAQVKPSGKTHQ-IRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDD 931
Query: 779 VSSDSENIPEEGDGSEELAHGHSSQS 804
S SE +G+ + +S
Sbjct: 932 SGSSSEESDSDGEAPAAVTSAQDQES 957
Score = 34.7 bits (78), Expect = 0.82
Identities = 72/353 (20%), Positives = 130/353 (36%), Gaps = 33/353 (9%)
Query: 460 EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSADSSSQKQNNKTEMYDKKTTDQAPNT 519
E EEE +E K+ + N LG D S +K +TE K T + P+
Sbjct: 86 ESSEEEEEAE--AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK-TGNSMPHP 142
Query: 520 DASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTA 579
++ +S R+ A+ + +S E +G S +G + G +
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-----SVPAFGAAAKPGMVSAGQAD 197
Query: 580 RNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNA------GIDFGSRKASA 633
+ + S ++ ++E + +P + S K+ R+ A G K A
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSV-STKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 634 AQPI-----PENMDNSMVSDPQPYHEDAASGAEKTEARASLSLM------VESLSTTQEE 682
P PE S S+ E+ A +++ +AS ++ + T +
Sbjct: 257 LPPAKRAKKPEEESES--SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 683 AILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFT 742
A + +A + + ++++ S + + S+ E+ + + + K SG Q
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA-AKALLQAKASGKTSQVGA 373
Query: 743 ASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEE 795
AS S KG A PP + K A + DS++ EE D EE
Sbjct: 374 ASAPAKESPR-KG---AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 422
Score = 32.3 bits (72), Expect = 4.1
Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 9/116 (7%)
Query: 177 KKEKEAEDTQEE-EMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFML 235
+K++++E ++EE + E + S + + S + + P ARA S+ G+ + +
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 236 GPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVP 291
+RS SK+ P P + S L + + VP V + A Q P
Sbjct: 817 AQAKQRSPSKVKP--------PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 864
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 45.8 bits (107), Expect = 4e-04
Identities = 60/241 (24%), Positives = 97/241 (40%), Gaps = 23/241 (9%)
Query: 1220 LPPNLPSKSLSKPEVKHQVFSDSGSANPKGG---ISSKMLPMKHPLQSLGRPEDPQKVFS 1276
L P LP ++ + E +H+ +G A P+ G +S + P P +K
Sbjct: 380 LTPLLPKSTIQEQE-RHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKP 438
Query: 1277 YSERAPGKCSSFKEQLSPRQL-SQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQ 1335
+ P K S+ K + P L Q P+S +S PPK +
Sbjct: 439 LATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS-----GLVPAAPPKRPAV 493
Query: 1336 ASDRSKFQPQMSSK----GPVNVPVKQSSGEKHLPSSSPFQQ------QVHSSSVNAAAR 1385
AS R P K P K++S K P+S+P + Q + + AAA
Sbjct: 494 ASARPSILPSKDVKPKPIADAKAPEKRASPSK--PASAPASRSGSKSTQTVAKTTTAAAV 551
Query: 1386 RSVFESNSDNWFLGRDEAFAIKTK-KFSQGSKNPIKSIPAPATKPGKFTIAPVRQTSTSG 1444
S S+ L + AIKT+ K ++ K KS+PA ++P + + +++T+T
Sbjct: 552 ASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLS 611
Query: 1445 G 1445
G
Sbjct: 612 G 612
Score = 37.7 bits (86), Expect = 0.096
Identities = 103/465 (22%), Positives = 169/465 (36%), Gaps = 93/465 (20%)
Query: 1226 SKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKC 1285
SK + PE K ++ K S P + + R +P K + ++ G
Sbjct: 325 SKGVRLPEPKDKILETPQKMTEK---SESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLT 381
Query: 1286 -----SSFKEQLSPRQLSQA-LRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQ---- 1335
S+ +EQ +QL A + +PE + V VS + K+LPP +
Sbjct: 382 PLLPKSTIQEQERHKQLKSAGIARPEEGRPV--VSGTGNDITTPPNKELPPSPEKKTKPL 439
Query: 1336 --------ASDRSKFQPQMSSKGPVNV--------PVKQSSGEKHLPSSSPFQQQVHSSS 1379
++ ++K QP K P P+ +SG +P++ P + V
Sbjct: 440 ATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL--VPAAPPKRPAV---- 493
Query: 1380 VNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQ 1439
A+AR S+ S + I K + +P K APA++ G + V +
Sbjct: 494 --ASARPSILPSKDV-------KPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAK 544
Query: 1440 TSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQ 1499
T+T+ + S +G + + L +K ++ + P K + K
Sbjct: 545 TTTAAAVAS------TGPSSRSPSTLLP-----KKPTAIKTEGKPAEVKKMTAK------ 587
Query: 1500 LASVP---SGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQP 1556
SVP S P S+S K +T G AAG + A SRP + K+P
Sbjct: 588 --SVPADLSRPKSTSTS-SMKKTTTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIDKKP 643
Query: 1557 ACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELK-TKSNAGADAETKEPKY 1615
P + S A + S +LK +S G+ T+ K+
Sbjct: 644 TSAKPSSTTPRLSRLA------------------TNTSAPDLKNVRSKVGS---TENIKH 682
Query: 1616 EGAGSANENQPKKMFTSSV-HKQEKTAQMKPPKPTKSVGFEAQKI 1659
+ G + Q KK+ S V K A +K V E+QK+
Sbjct: 683 QPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKL 727
Score = 33.9 bits (76), Expect = 1.4
Identities = 115/522 (22%), Positives = 184/522 (35%), Gaps = 93/522 (17%)
Query: 795 ELAHGH-------SSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDA 847
ELA GH QSL E +++ +F EE + + S A++ P+
Sbjct: 176 ELAKGHLLPGVPVEDQSLPGEARALEGYADRGNF--PAHPVNEEKETKEGSVAVQIPDLL 233
Query: 848 EVFTESSSYVEKYNTSD------DCSSSEEDLPLRHPAQALGKPKNQQ------EVSSAS 895
E + S+ E N D D + + DL L P K K E+ S S
Sbjct: 234 EDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVS 293
Query: 896 NNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQ-SDSVEPIPPR-----H 949
TPE Q+DF+ PS+ + + V + T+S G + + D + P +
Sbjct: 294 LPTPEIQSDFLHSKVEAPPSE-VADTLV---IMTASKGVRLPEPKDKILETPQKMTEKSE 349
Query: 950 PFQPWVNPKVEQEVSSSPKS--MAVEESISMKPLPPKLLCQP-----------LMNPKVQ 996
P K ++ + P M +S + PL PK Q + P+
Sbjct: 350 SKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEG 409
Query: 997 QNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEEGT------------ 1044
+ + SG+ + P P + L Q + S S A + T
Sbjct: 410 RPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIG 469
Query: 1045 ------------YVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPV--APTPSKYTSP--P 1088
V PP+ + S RP L S + P+ A P K SP P
Sbjct: 470 GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK---PIADAKAPEKRASPSKP 526
Query: 1089 WVTPKFEELYQLSAHPESTTVEEDI--------SKEQLLPRHLSQLTVGNKVQQLSSNFE 1140
P + + TT + S LLP+ + + K ++
Sbjct: 527 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEV-KKMT 585
Query: 1141 RAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRP-TQSFV-- 1197
++ AD+S P +T +K++ T+ + V +P+P RP T F+
Sbjct: 586 AKSVPADLS---RPKSTSTSSMKKTTTLSGTAPAAGV-VPSRVKATPMPSRPSTTPFIDK 641
Query: 1198 KFMAQQIFSESSALKR--GSDVAPLPPNLPSKSLSKPEVKHQ 1237
K + + S + L R + AP N+ SK S +KHQ
Sbjct: 642 KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ 683
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 45.4 bits (106), Expect = 5e-04
Identities = 108/484 (22%), Positives = 176/484 (36%), Gaps = 72/484 (14%)
Query: 825 LSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTS---DDCSSSEEDLPLRH--PA 879
+ + EEE+ L +S AL + + E + ++ DD S+ E+L +H P+
Sbjct: 969 IKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPS 1028
Query: 880 QALG---KPKNQQEVSSASNNTPEEQN-DFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTS 935
+ G P + S + T E + PSR PS+ P+ Q + T
Sbjct: 1029 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1088
Query: 936 IKQSDSVEPI-----PPRHPFQPWVNPKVEQEV-----SSSPKSMA-------VEESISM 978
+ Q D +P+ PP P P P Q S P A S +
Sbjct: 1089 LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTAR 1148
Query: 979 KPLPPK--LLCQPLMNPKVQQNMF-----SGSEDIAVERVISVEPLLPR--YSPQSLTDP 1029
+PP+ ++ P + + S + + + EPL P+ + PQS P
Sbjct: 1149 PTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1208
Query: 1030 QIRQISESTAVEEGTYVEPLP-PRCLSQPSERPKFLDSMSTSAEWSS-PVAPT----PSK 1083
+++ E + P P + P P+ S S +E SS P T K
Sbjct: 1209 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK 1268
Query: 1084 YTSPPWVTPKFEEL-YQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERA 1142
SP + P FE+L + L A ++ + P+ L QL + LSS
Sbjct: 1269 RESPLKIDP-FEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSS----- 1322
Query: 1143 AIEADISGSP-LPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMA 1201
+S P +PP A RS+ QE + G + +P R F A
Sbjct: 1323 -----VSCMPTMPPIPA-----RSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRA 1372
Query: 1202 QQIFSESS---ALKRGSDVAPLPPNLP-SKSLSKPEVKHQVFSDSGS---------ANPK 1248
+ SE++ + + ++P P P + S+ F DS +NPK
Sbjct: 1373 KSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPK 1432
Query: 1249 GGIS 1252
G ++
Sbjct: 1433 GWVT 1436
Score = 35.0 bits (79), Expect = 0.63
Identities = 56/245 (22%), Positives = 88/245 (35%), Gaps = 13/245 (5%)
Query: 1235 KHQVFSDSGSANPKGGISSKMLPMKHPLQSLGR-PEDPQKVFSYSERAPGKCSSFKEQLS 1293
+H S S S + P + P S G P P + R PG S+ Q S
Sbjct: 1023 QHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA---QSS 1079
Query: 1294 PRQLSQALRKPEYE--QKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGP 1351
P A P+ + Q + P P+ + PP+ S RS+ PQ GP
Sbjct: 1080 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGP 1139
Query: 1352 VNVPVKQSSGEKHLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKF 1411
P S+ +P + S A+A R ES S + F + K
Sbjct: 1140 --GPAGYSTARPTIPPRAGV-ISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLK- 1195
Query: 1412 SQGSKNPIKSIPAPATK---PGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNNQHANLSN 1468
Q + P S+P PA + P AP+ Q+ + + + +++ + S+
Sbjct: 1196 PQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1255
Query: 1469 QDDVE 1473
Q V+
Sbjct: 1256 QPQVK 1260
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 45.4 bits (106), Expect = 5e-04
Identities = 125/622 (20%), Positives = 224/622 (36%), Gaps = 91/622 (14%)
Query: 558 KQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDM 617
K G GD KT + + L + E S+ T QG + +
Sbjct: 1756 KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQ 1815
Query: 618 GRRNAGIDFGSRKASAAQPI--PENMDNSMVSDPQPYHEDAASGAEKTEARASLSLMVES 675
G AG D ++ A+ I PE + +A A++ E A ES
Sbjct: 1816 GEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQ----PES 1871
Query: 676 LSTTQEEAILSVAAEAQVFMNPS---HIQLEDQEAFSFDLQK-AQSKMESAQDVQTICKE 731
EA E++ P +Q E + A + + +K AQ + ES + ++T ++
Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931
Query: 732 KPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSR-----KPDAEEVSS---DS 783
+P + A A + +T P + +S +P++E+V + +
Sbjct: 1932 EPESEGAEAQEAE-------EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984
Query: 784 ENIPEEGDGSEELAHGHSSQSLGKFEDEQE--------VFSESKSFVEDLSSSEEEL--- 832
E EG+ E + ++ G+ ++ +E V ++ KS E+ E E
Sbjct: 1985 ETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKT 2044
Query: 833 --DLRCLSQALEEPEDAEVFTESSSYV-----EKYNTSDDCSSSEEDLPLRHPAQALGKP 885
D + S +E PE E E+ V E + S+D + E + + ++ + P
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAP 2104
Query: 886 KNQQEVSSASN-NTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIK------- 937
+ + E A PE + + + S+ I P + + S G +
Sbjct: 2105 EAEGEAQKAEGIEAPETEGEAQPE------SEGIEAPEAEGEAQPESEGVEAQDAEGEAQ 2158
Query: 938 -QSDSVEPIPPRHPFQPWVN--PKVEQEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPK 994
+S+ +E QP + E E + P+S +E + P+L + + P+
Sbjct: 2159 PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPEL--EGVEAPE 2216
Query: 995 VQQNMFSGSEDIAV-ERVISVEPLL-------PRYSPQ-SLTDPQIRQISESTAVEEGTY 1045
++ E + E +P + SPQ SL D Q + SES++
Sbjct: 2217 AEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDR 2276
Query: 1046 VEPLPPRCLSQPSERP--KFLDSMSTSAEWSS-------------PVAPTPSKYTSPPWV 1090
P P P +RP + S S ++ W + +K T P
Sbjct: 2277 PTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHA 2336
Query: 1091 TPKFEELYQLSAHPESTTVEED 1112
K +Y PES+T E++
Sbjct: 2337 ERKATRMY-----PESSTSEQE 2353
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 45.4 bits (106), Expect = 5e-04
Identities = 241/1251 (19%), Positives = 414/1251 (33%), Gaps = 146/1251 (11%)
Query: 496 SSSQKQNNKTEMYDKKTTDQAP-------NTDASRSQGYPMSAAYGRRWRRKGASVSGLS 548
SSS+++N + ++ +P ++ SRS P S A R R+ S+SG S
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR--SLSGSS 783
Query: 549 GCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLE----KDNMEQPTTSQPET 604
C KQ S+ R+GSS +R P S K + P+ +
Sbjct: 784 PCP------KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 605 TTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTE 664
++P + K R I S +A+ P+ + S P P E + +
Sbjct: 838 SSPHPKV--KSGTPPRQGSIT--SPQANEQSVTPQRR-SCFESSPDP--ELKSRTPSRHS 890
Query: 665 ARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQD 724
S V+S + ++ S + + +V I Q + S + S++ S
Sbjct: 891 CSGSSPPRVKSSTPPRQSPSRSSSPQPKV----KAIISPRQRSHSGSSSPSPSRVTSRTT 946
Query: 725 VQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSS---------RKPD 775
+ P NV S++ V +T PPR S + P
Sbjct: 947 PRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPET-PPRQSHSGSISPYPKVKAQTPP 1005
Query: 776 AEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLR 835
+S P+E + S SL ES V L +
Sbjct: 1006 GPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP 1065
Query: 836 CLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSA- 894
PE + +ES S K TS S P+ A +++ E S++
Sbjct: 1066 DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASP 1125
Query: 895 ---SNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPF 951
S +PE+ SR S PTV +S +PP+
Sbjct: 1126 MLKSGMSPEQ---------SRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176
Query: 952 QPWVNPKVEQEVSSSPKSMAVEESISMKPL---PPKLLCQPLMNPKVQQN---MFSGSED 1005
P+ + + S P E S+ K PP+ +P+ ++ + + S+D
Sbjct: 1177 TA-SPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQD 1235
Query: 1006 IAVERVI--SVEPL--LPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERP 1061
+ V+ S EP + + L + S VEE V + SQ S
Sbjct: 1236 EELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEA 1295
Query: 1062 KFLDSMSTSAEWSSP-VAPTPSKYTSPPWVTPKFEELYQL-SAHPESTTVEEDIS---KE 1116
+ SM++S W P +P + ++ P F + ++ P T + S KE
Sbjct: 1296 VEVPSMASS--WGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKE 1353
Query: 1117 QLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSPLPPQYATQFLKRSK---------- 1166
L L+QL + E++ + S S L P + S
Sbjct: 1354 DLNGPFLNQLETDPSLDMK----EQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDA 1409
Query: 1167 VQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLPS 1226
V SR + K +PR P++ + S L+ GS P+ S
Sbjct: 1410 VPRTPSRERSSSASSPEMKDGLPRTPSR-------RSRSGSSPGLRDGSGT----PSRHS 1458
Query: 1227 KSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCS 1286
S S P +K D +G P L RP R+P
Sbjct: 1459 LSGSSPGMK-----DIPRTPSRGRSECDSSPEPKALPQTPRPRS---------RSPSSPE 1504
Query: 1287 SFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQM 1346
+ L+P Q ++ + +QK + + S ++L K S+ +RS+
Sbjct: 1505 LNNKCLTP-QRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSP 1563
Query: 1347 SSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAI 1406
SK P++Q S SSP V++ +R S S S + +D+ A
Sbjct: 1564 DSKAKTRTPLRQRSRS----GSSP--------EVDSKSRLSPRRSRSGSSPEVKDKPRAA 1611
Query: 1407 KTKKFSQGSKNPIKSIPAPATKPGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNNQHANL 1466
+ S +P PAP P + S SG S K S +G+++ +
Sbjct: 1612 PRAQ-SGSDSSPEPKAPAPRALP---------RRSRSGS--SSKGRGPSPEGSSSTES-- 1657
Query: 1467 SNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLL 1526
S + + R R+ P K KS S P + + R + S+S
Sbjct: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETR 1717
Query: 1527 DAAGNLTKISYVADKQQSRPKSESMAKKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQ 1586
+ S + KS S +++ A K ++ +P + ++ +
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
Query: 1587 KSFKAHISVKELKTKSNAGADAETKEPKYEGAGSANENQPKKMFTSSVHKQEKTAQMKPP 1646
+ K + + ++ S+ + + + + S +QE +
Sbjct: 1778 RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
Query: 1647 KPTKSVGFEAQKILQVPAMEKETKRSSTLPAKFQNPVEPIEPVWFSLARKK 1697
+ +S + P ++ RS T PA ++ P +R +
Sbjct: 1838 RRGRS---------RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879
Score = 33.9 bits (76), Expect = 1.4
Identities = 44/202 (21%), Positives = 76/202 (37%), Gaps = 18/202 (8%)
Query: 194 SLSSSNINISSLQPV--RENQPTKARAKSSMGSKALSHDSIFMLGPEPERSASKMFPSMD 251
+L+S + +S+ + V R + P RA+S A P R S+ PS
Sbjct: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSA----------PSQSRMTSERAPSPS 2428
Query: 252 PQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPT----SAVWVAGPKITENPP 307
+ G+ +S + +PRS VP S + Q P S A T +
Sbjct: 2429 SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAG 2488
Query: 308 SRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHKSLTATQSFSELSSGPDC 367
LS+ P + + + S + A +S +++ S S SS
Sbjct: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS 2548
Query: 368 SQSLTAFATLASTSS--TQLPI 387
S S ++ + +S+ S + LP+
Sbjct: 2549 SSSSSSSSGSSSSDSEGSSLPV 2570
Score = 33.1 bits (74), Expect = 2.4
Identities = 91/420 (21%), Positives = 141/420 (33%), Gaps = 77/420 (18%)
Query: 573 SPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKAS 632
S N T+ VP S P + + TP S R +A
Sbjct: 2376 SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP 2435
Query: 633 AAQPIPENMDNSMVSDPQPYHEDAASG-AEKTEARASLSLMVESLSTTQEEA-----ILS 686
+ +P D P + + + A+ T S SL +++TT A +LS
Sbjct: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495
Query: 687 VAA----EAQVFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFT 742
V A + V P+ + A + LQ A+ + S+ + S + + +
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAA-LQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
Query: 743 ASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDS--ENIPEEGDGSEELAHGH 800
+S G +S+ ++G +LP + R P ++ E P E ++
Sbjct: 2555 SS--GSSSSDSEGS----SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608
Query: 801 SSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKY 860
SS S S S S SSS + SSS
Sbjct: 2609 SSSS-----------SSSSSSSSSSSSSSS--------------------SSSSSSSSSS 2637
Query: 861 NTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMN 920
++S SSS P + QAL KP +S P E+ SR P +PI
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKP------ASPKKPPPGERR-------SRSPRKPI-- 2682
Query: 921 PTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEESISMKP 980
S+ S +S S P+ R P P +P+ +Q SS S + S P
Sbjct: 2683 ---------DSLRDS--RSLSYSPVERRRP-SPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Score = 32.7 bits (73), Expect = 3.1
Identities = 55/218 (25%), Positives = 86/218 (39%), Gaps = 26/218 (11%)
Query: 1212 KRGSDVAPL--PPNLPSKSLSKPEVK-HQVFSDSGSANPKGGISSKMLPMKHPLQSLGRP 1268
+RG AP P ++ S PE Q S + S P P +S P
Sbjct: 302 RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP 361
Query: 1269 EDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRN---SK 1325
E P +ER G SP+ L+ P ++ V+P S +SP R+ S
Sbjct: 362 EPPAPTPLLAERHGG---------SPQPLATT---PLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 1326 KQLPPKHSSQASDRSKFQPQMS---SKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSVNA 1382
++LP SS++S S ++S S P + + G SSSP + +
Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSP----TSKNRSHG 465
Query: 1383 AARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIK 1420
A+R S++ + +GR + A K+ S+ P K
Sbjct: 466 RAKRDKSHSHTPSRRMGRSRSPA-TAKRGRSRSRTPTK 502
Score = 32.7 bits (73), Expect = 3.1
Identities = 95/432 (21%), Positives = 147/432 (34%), Gaps = 81/432 (18%)
Query: 1189 PRRPTQSFVKFMAQQIFSESSALK-RGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANP 1247
PR PT V + + +AL GS P N PS S + P+ SAN
Sbjct: 2287 PRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRT-PQAP-------ASANL 2338
Query: 1248 KGGISSKMLPMKHPLQSLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYE 1307
G S+ P+ G S + A S +++P L P
Sbjct: 2339 VGPRSAHATA---PVNIAG---------SRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
Query: 1308 ----QKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEK 1363
++VS +SP ++ + PP SQ+ S+ P SS+ + Q+ +
Sbjct: 2387 LSAYERVS--GRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSR------MGQAPSQS 2438
Query: 1364 HLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDE--AFAIKTKKFSQGSKNPIKS 1421
LP P Q Q S +A + +S G + A+ T S G N + S
Sbjct: 2439 LLP---PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495
Query: 1422 IPAP---------------ATKPGKFTI---APVRQTSTSGGIYSKKEDLESGDGNNNQH 1463
+PAP A +P A R++S+S S S +++
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
Query: 1464 ANLSNQDDVEKLFGVR----LKRAP-----PSQ-------------KYKSEKQDNFTQLA 1501
+ S+ D V+ LKR P P + K K + + +
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 1502 SVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESMAKKQPA---C 1558
S S SSS S+S ++ + + S Q+ PK S K P
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675
Query: 1559 KTPGKPAGQQSD 1570
++P KP D
Sbjct: 2676 RSPRKPIDSLRD 2687
Score = 32.0 bits (71), Expect = 5.3
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 7/118 (5%)
Query: 215 KARAKSSMGSKALSHDSIFMLGPEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKV 274
KA A ++ ++ S S GP PE S+S P + R +R S PK +S+
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684
Query: 275 PGVVSGAMSGAVLQNVP----TSAVWVAGPKITENPPSRRRRLSIIPPVIQPEIISKN 328
P + S L S + P+ P R RR P V PE K+
Sbjct: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR---SPSVSSPEPAEKS 1739
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 45.1 bits (105), Expect = 6e-04
Identities = 48/193 (24%), Positives = 74/193 (38%), Gaps = 24/193 (12%)
Query: 436 ILEGSLQCVTQTLETPNLDEPLPV-EPKEEEPNLPLVSEEEKSITKPKEINEKKLGMDSA 494
+ E S+Q T T + + +P P+ EPKE P E+EK T+P+ + K +
Sbjct: 230 VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTR 289
Query: 495 DSS------SQKQNNKTEMYDKKTTDQAPNTDASRSQGYP----------MSAAYGRRWR 538
S ++ +++ Y + + R + P S + RR R
Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349
Query: 539 RKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPT 598
R AS+SG S RS + + SSP KT R P + + P
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKK----PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA 405
Query: 599 TSQPET---TTPQ 608
T P+T TPQ
Sbjct: 406 TPPPKTRHSPTPQ 418
Score = 39.7 bits (91), Expect = 0.025
Identities = 148/745 (19%), Positives = 246/745 (33%), Gaps = 131/745 (17%)
Query: 805 LGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSD 864
L K E +Q + K + + +E+ D R EE E + E S + S
Sbjct: 126 LKKEEIKQRQIEQEK--LASMKKQDEDKDKR----DKEEKESSREKRERSRSPRR-RKSR 178
Query: 865 DCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQ 924
S P+R + + S S + E+ + +LP PS + P+VQ
Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE--PSVKVKEPSVQ 236
Query: 925 QQVPTSSVGTSIKQSDSVEPIP-PRHPFQPWVNPKVEQEVSSS-PKSMAVEESISMKPLP 982
+ TS I + EPIP P+ P P N K E+E + P+S + +S S
Sbjct: 237 EATSTSD----ILKVPKPEPIPEPKEP-SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291
Query: 983 PKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQ--------IRQI 1034
+P + + +S + R S P P+ + P +R+
Sbjct: 292 SPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP---PRRMPPPPRHRRSRSPVRRR 348
Query: 1035 SESTAVEEGTYVEPLPPRCLSQPSERPKFLDS-------MSTSAEW-------SSPVAPT 1080
S+A G+ R S P + PK S +S SA S P P
Sbjct: 349 RRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP 408
Query: 1081 PSKYTSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFE 1140
P SP ++S P T+ + K S KV+ S +
Sbjct: 409 PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEED 468
Query: 1141 RAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNK--------------- 1185
+ A QY Q + S +S E + + K
Sbjct: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
Query: 1186 -SPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPP---------------------- 1222
SP PR+ + ++ +R +P PP
Sbjct: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
Query: 1223 NLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKH-------PLQSLGRPEDPQKVF 1275
PS P ++ + S S PK +S P K P + + P++
Sbjct: 589 RSPSPRRYSPPIQRRY---SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRS 645
Query: 1276 S--YSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHS 1333
S R+P S ++ SP + ++ R P+ ++ SP + P+ + S P +
Sbjct: 646 SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP--SPRPRAPQTSSSPPPVRRG 703
Query: 1334 SQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQQVH--------SSSVNAAAR 1385
+ +S + + P S++ P+ + +K ++SP Q V S S AA+
Sbjct: 704 ASSSPQRRQSPSPSTR-PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK 762
Query: 1386 RS-------VFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFTIAPVR 1438
+ +S S NW P+K +P P +P R
Sbjct: 763 KPPAPPSPVQSQSPSTNW-----------------SPAVPVKKAKSPTPSP-----SPPR 800
Query: 1439 QTSTSGGIYSKKEDLESGDGNNNQH 1463
+ GG KK+ + + +H
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKH 825
Score = 35.0 bits (79), Expect = 0.63
Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 14/138 (10%)
Query: 177 KKEKEAEDTQEEEMLELSLSSSNINISSLQPVRENQPTKARAKSSMGSKALSHDSIFMLG 236
KKEKE E T+ S S R P+ R + S++ S+
Sbjct: 266 KKEKEKEKTRPR---------SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316
Query: 237 PEPERSASKMFPSMDPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAVW 296
P S + P P+R P R SR+ + R + +SG+ S + + + +
Sbjct: 317 PRRRPSPRRRTP---PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSS--SSSRSRSPP 371
Query: 297 VAGPKITENPPSRRRRLS 314
PK T +PP + RRLS
Sbjct: 372 KKPPKRTSSPPRKTRRLS 389
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.3 bits (103), Expect = 0.001
Identities = 111/560 (19%), Positives = 201/560 (35%), Gaps = 60/560 (10%)
Query: 1150 GSPLPPQYATQFLKRS----KVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIF 1205
G P P +T +S KV E + + E + VE + ++ + T+ K ++
Sbjct: 425 GLPKIPSVSTHIKVKSEEKIKVVEKSEK-ETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483
Query: 1206 SESSA-----LKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKH 1260
E + G + PP ++ + PE + + + +P S + K
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPP---AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 1261 PLQSLGRPEDPQKVFSYSERAP--GKCSSFKEQLSPRQLS--QALRKPEYEQKVSPVSAS 1316
P + + PE + ++P K +E SP ++ + + P E+ SP A
Sbjct: 541 PAE-VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599
Query: 1317 SPKEWRNSKKQ---LPPKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEKHLPSSSPFQQ 1373
SP++ ++ K+ P + S + +K ++ S P K+ E P + +
Sbjct: 600 SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE---EAKSPEKAKSPE 656
Query: 1374 QVHSSSVNAAARRSVFESNSDNWFLGRDEAFAIKTKKFSQGSKNPIKSIPAPATKPGKFT 1433
+ + S A E+ S +A A +K K KS P A P K
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS-PEKAKSPVKEE 715
Query: 1434 I-APVRQTSTSGGIYSKKEDLESGDGNNNQHANLSNQDDVEKLFGVRLKRA-PPSQKYKS 1491
+P + S E +S + + + K V+ A P+++
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 1492 EKQDNFTQLASVPSGPISSSVGRGHKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSESM 1551
D F + A P+ V K +S K+ ++ + +
Sbjct: 776 SPADKFPEKA---KSPVKEEVKSPEKAKSPL------------------KEDAKAPEKEI 814
Query: 1552 AKKQPACKTPGKPAGQQSDYAVSEPVWITMAKQKQKSFKAHISVKELKTKSNAGADAETK 1611
KK+ K+P K + + V EP +K + KA + K + K + +A K
Sbjct: 815 PKKEEV-KSPVKEEEKPQEVKVKEP------PKKAEEEKAPATPKTEEKKDSKKEEAPKK 867
Query: 1612 E---PKYEGAGSANENQPKKMFTSSVHKQEKTAQMKPPKPTKSVGFEAQ-KILQVPAMEK 1667
E PK E +PK+ + K+E + K P P K + + K P +
Sbjct: 868 EAPKPKVEEKKEPAVEKPKESKVEA-KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Query: 1668 ETKRSSTLPAKFQNPVEPIE 1687
E + AK + P +P E
Sbjct: 927 EVAKKEPDDAKAKEPSKPAE 946
Score = 38.9 bits (89), Expect = 0.043
Identities = 111/593 (18%), Positives = 206/593 (34%), Gaps = 63/593 (10%)
Query: 807 KFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPE----DAEVFTESSSYVEKYNT 862
K + E+++ KS E + E+ + + + EE E + E E E+
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496
Query: 863 SDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPT 922
++ + S P + P ++ S A +PE++ + P+ S
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE---AKSPAEVKSPEKAKSP 553
Query: 923 VQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEESISMKPLP 982
+++ + S ++ ++ P + P + ++E S ++ + E++ S P+
Sbjct: 554 AKEEAKSPPEAKSPEKEEAKSPAEVKSPEK--AKSPAKEEAKSPAEAKSPEKAKS--PVK 609
Query: 983 PKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEE 1042
+ V++ S +E + E+ S + SP+ P+ + +
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK-SPEKAKSPEKEEAKSPEKAKS 668
Query: 1043 GTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPV---APTPSKYTSPPWVTPKFEELYQ 1099
E P P + + + SPV A +P K SP K E +
Sbjct: 669 PVKAEAKSPEKAKSPVKA-----EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723
Query: 1100 LSAHPESTTVEE---DISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSPLPPQ 1156
E+ T E+ + +E P + S + A E S + P+
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 1157 YATQFLK---------RSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSE 1207
A +K +S ++E EK + KSP+ VK +
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV-------K 836
Query: 1208 SSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLP-MKHPLQSL- 1265
K + AP P K SK E + PK + K P ++ P +S
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPK------KEAPKPKVEEKKEPAVEKPKESKV 890
Query: 1266 ----GRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALRKPEYEQKVSPVS------- 1314
ED +KV + + AP K KE P++ ++ +K + K S
Sbjct: 891 EAKKEEAEDKKKVPTPEKEAPAKVE-VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Query: 1315 -ASSPKEWRNSKKQLP---PKHSSQASDRSKFQPQMSSKGPVNVPVKQSSGEK 1363
A K+ + K + P PK ++A + K + SK K SS ++
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQ 1002
>gi|12232415 hypothetical protein LOC64762 [Homo sapiens]
Length = 875
Score = 43.9 bits (102), Expect = 0.001
Identities = 107/459 (23%), Positives = 165/459 (35%), Gaps = 112/459 (24%)
Query: 870 EEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPT 929
+ +LP GKP +Q S S +Q F + S+C + P+ P
Sbjct: 448 KSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQ--FRGSVRSKCATSPLPIP-------- 497
Query: 930 SSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEES---ISMKPLPPK-- 984
++G ++K SD+ P PP PKS AV E ++ P+PP+
Sbjct: 498 GTLGAAVKSSDTALPPPP-----------------VPPKSEAVREECRLLNAPPVPPRSA 540
Query: 985 --LLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSP--QSLTDPQIRQISESTAV 1040
L P + P+ + A ++ S P L YS ++ SEST V
Sbjct: 541 KPLSTSPSIPPRTVKP--------ARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPV 592
Query: 1041 EEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPWVTPKFEELYQL 1100
P R K DS+ + + SP A S S P
Sbjct: 593 S-------------CYPCNRVK-TDSVDLKSPFGSPSAEAVSSRLSWP---------NHY 629
Query: 1101 SAHPESTTVEE---DISKEQLLPRHLSQLTVGNKVQQLSSNFE--------------RAA 1143
S ES T + D S+ PR Q T G + + F+ A
Sbjct: 630 SGASESQTRSDFLLDPSRSYSYPR---QKTPGTPKRNCPAPFDFDGCELLASPTSPVTAE 686
Query: 1144 IEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQ 1203
+ +SG P Y+ L+ + V+ + + + K + TS + PR P K + ++
Sbjct: 687 FSSSVSGCPKSASYS---LESTDVKSLAAGVTK---QSTSCPALPPRAP-----KLVEEK 735
Query: 1204 IFSESSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQ 1263
+ SE+S L D A P S LS + Q F G + I S P PL
Sbjct: 736 VASETSPLPLKIDGAEEDPKSGSPDLS----EDQYFVKKGMQD----IFSASYPFSSPLH 787
Query: 1264 SLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALR 1302
P S + +P + + LS ++S++LR
Sbjct: 788 LQLAPR------SCGDGSPWQPPADLSGLSIEEVSKSLR 820
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 25/195 (12%)
Query: 791 DGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVF 850
D E A SS + +DE++ E + D + E E+ + E E+++
Sbjct: 962 DSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEV-------SDGEDEESDSS 1014
Query: 851 TESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSA-SNNTPEEQNDFMQQL 909
++ S Y + +D S SE + + + SS+ S++ EE+ + L
Sbjct: 1015 SKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAAL 1074
Query: 910 PSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVE-PIPPRHPFQPWVNPKVEQEVSSSPK 968
PS P P + VPT + VE P+P R P V P EQE S +
Sbjct: 1075 PSASP------PPREVPVPTPA---------PVEVPVPERVAGSP-VTPLPEQEASPARP 1118
Query: 969 SMAVEESISMKPLPP 983
+ EES PL P
Sbjct: 1119 AGPTEESPPSAPLRP 1133
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 43.9 bits (102), Expect = 0.001
Identities = 191/964 (19%), Positives = 324/964 (33%), Gaps = 127/964 (13%)
Query: 338 SPKNPQKKALPHKSLTATQSFSELSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQG 397
SP + ++P + T +++ + L+S P + T A+ + + + P+ STP TT
Sbjct: 2791 SPTTAEVTSMP--TSTPSETSTPLTSMP---VNHTPVASSEAGTLSTTPVDTSTPVTTST 2845
Query: 398 CLDSSAARHKMTLNPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPL 457
SS + + P ++ +PV + TL T +D +
Sbjct: 2846 KASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPV-------ASSEASTLSTTPVDTSI 2898
Query: 458 PVEPKEEEPNLPLVSE-EEKSITKPKEINE----------KKLGMDSADSSSQKQNNKTE 506
PV E + P +E I+ P E++ G +++ S+ + +T
Sbjct: 2899 PVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTP 2958
Query: 507 MYDKKTTDQAPNTDASRSQGYPMSAAYGRRWRRKGASVSGL----SGCEFKGRSLKQSSE 562
+ +P T S P+S RR SVS + S R+ +S
Sbjct: 2959 VTTSAEASSSPTTAEGTSM--PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTST 3016
Query: 563 GYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNA 622
A SSPT +P S S P TS P +TTP + +
Sbjct: 3017 PVTTSTEASSSPTTAEGTGIPISTPS----EGSTPLTSIPVSTTPVAI---PEASTLSTT 3069
Query: 623 GIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAASGAEKTEARAS--LSLMVESLSTTQ 680
+D S ++ + S P + + ++ + S + +LSTT
Sbjct: 3070 PVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTP 3129
Query: 681 EEAILSVAAEAQVFMNPSHIQ---------------LEDQEAFSFDLQKAQSKMESAQDV 725
+ V + +P+ + L + + ++ SA V
Sbjct: 3130 VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPV 3189
Query: 726 QTICKEKPSGNVHQTFTASVLGM-TSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSE 784
T S + TA + TST ++G ++P + +S + +
Sbjct: 3190 DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDS 3249
Query: 785 NIP----EEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQA 840
N P E S A G S + E + S S SS E L
Sbjct: 3250 NTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS--ETSTLSTTPAD 3307
Query: 841 LEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPE 900
P SS + + + SE PL + + + P E S+ S TP
Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFST-TPVVSSEASTLS-TTPV 3365
Query: 901 EQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVE 960
+ S P+ T PT++ GTSI S E P
Sbjct: 3366 D------------TSTPVTTSTEASLSPTTAEGTSIPTSSPSE----------GTTPLAS 3403
Query: 961 QEVSSSPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPR 1020
VS++P + ++S P+ L S S IA +
Sbjct: 3404 MPVSTTPVVSSEVNTLSTTPVDSNTLV-------TTSTEASSSPTIAEGTSLPTSTTSEG 3456
Query: 1021 YSPQSLTDPQIRQISESTA-VEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAP 1079
+P S+ ++ S A T V+ P S P+ +S T+AE +S
Sbjct: 3457 STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT------NSSPTTAEVTSMPTS 3510
Query: 1080 TPSKYTSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNF 1139
T + ++P L+ P STT P S+ + + S+ F
Sbjct: 3511 TAGEGSTP------------LTNMPVSTT-----------PVASSEASTLSTTPVDSNTF 3547
Query: 1140 ERAAIEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRP-TQSFVK 1198
++ +A S SP Q T ++ S E +S L M + T S P T S +
Sbjct: 3548 VTSSSQA--SSSPATLQVTT--MRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR 3603
Query: 1199 FMAQQIFSESSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPM 1258
++S++ +V LP + PS+ +S P V + S + + G S+ +
Sbjct: 3604 STPVTTSTQSNSTPTPPEVITLPMSTPSE-VSTPLTIMPVSTTSVTISEAGTASTLPVDT 3662
Query: 1259 KHPL 1262
P+
Sbjct: 3663 STPV 3666
Score = 38.1 bits (87), Expect = 0.074
Identities = 186/916 (20%), Positives = 299/916 (32%), Gaps = 160/916 (17%)
Query: 291 PTSAVWVAGPKITENPPSRRRRLSIIPPVIQPEIISKNLVEISLDDESPKNPQKKALPHK 350
PT+A G I +PPS PV ++S +S P +
Sbjct: 2438 PTTA---EGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEAS 2494
Query: 351 S--LTATQSFSELSSGPDCSQSLTAFATL--------ASTSSTQLPIGFSTPATTQGCLD 400
S TA +S+ + S LT+ AST ST P+ ++P T +
Sbjct: 2495 SSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTT-PVDSNSPVVTSTEIS 2553
Query: 401 SSAARHKMTLNPRKQKKNLQVIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVE 460
SSA + T P +R +PV + TL T +D +PV
Sbjct: 2554 SSATSAEGTSMPTSTYSEGSTPLRSMPV-------STKPLASSEASTLSTTPVDTSIPVT 2606
Query: 461 PKEEEPNLPLVSEE-EKSITKPKEINEKK---LGMDSADSSSQKQNNKTEMYDKKTTDQA 516
E + P +++ I+ P E++ L +SS+ T D +T
Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTL--- 2663
Query: 517 PNTDASRSQGYPMSAAYGRRWRRKGASVSGLSGCEFKGRSLKQSSEGYGLGDRAGSSPTN 576
T ++ + P +A +G S+ S+ G S+P
Sbjct: 2664 -VTTSTGTSSSPTTA---------------------EGSSMPTSTPG------ERSTPLT 2695
Query: 577 KTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDKDDMGRRNAGIDFG-SRKASAAQ 635
N+ S L +T+ +T+TP ++ G S + +
Sbjct: 2696 ----NILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGST 2751
Query: 636 PIPENMDNSMVSDPQPYHEDAASGAEKTEARASL----SLMVESLSTTQEEAILSVAAEA 691
P+ S++ P AS T S+ S S TT E + + +
Sbjct: 2752 PL-----TSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPS 2806
Query: 692 Q-----VFMNPSHIQLEDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASVL 746
+ M +H + EA + + + ++++ V T K S T ++
Sbjct: 2807 ETSTPLTSMPVNHTPVASSEAGTL----STTPVDTSTPVTTSTKASSS----PTTAEGIV 2858
Query: 747 GMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIP----EEGDGSEELAHGHSS 802
ST ++G ++P + +S + + +IP EG S A G S
Sbjct: 2859 VPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSM 2918
Query: 803 QSLGKFEDEQEVFSESKSFVEDLSSSEEELD---------LRCLSQALEEPEDAEVFTES 853
E + S S V S L + ++A P AE +
Sbjct: 2919 PISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMP 2978
Query: 854 SSYVEKYNT--------SDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASN--------- 896
S + T + +SSE R PA E SS+
Sbjct: 2979 ISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPI 3038
Query: 897 NTPEEQNDFMQQLP-SRCP----------------SQPIMNPTVQQQVPTSSVGTSIKQS 939
+TP E + + +P S P + P++ T PT + GTS+ S
Sbjct: 3039 STPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS 3098
Query: 940 DSVEPIPPRHPFQPWVNPKVEQEVS---------SSPKSMAVE--------ESISMKPLP 982
E P P +S S+P + + E E SM
Sbjct: 3099 TYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTST 3158
Query: 983 PKLLCQPLMNPKVQQNMFSGSED--IAVERVISVEPLLPRYSPQSLTDPQIRQISESTAV 1040
P PL V + SED ++ V + P+ S T + I ST
Sbjct: 3159 PSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPS 3218
Query: 1041 EEGTYVEPLPPRCLSQPSERPKFLDS--------MSTSAEWSSPVAPTPSKYTSPPWVTP 1092
E T + +P S L + ++TS E SS +P ++ TS P TP
Sbjct: 3219 EGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASS--SPPTAEGTSMPTSTP 3276
Query: 1093 KFEELYQLSAHPESTT 1108
E L++ P STT
Sbjct: 3277 S-EGSTPLTSMPVSTT 3291
Score = 37.4 bits (85), Expect = 0.13
Identities = 56/222 (25%), Positives = 88/222 (39%), Gaps = 31/222 (13%)
Query: 915 SQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVS---------S 965
S P+ T + PT+S GTS+ S E P P + E S S
Sbjct: 1718 STPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTS 1777
Query: 966 SPKSMAVEESISM-----KPLPPKLLCQ---PLMNPKVQQNMFSGSE--DIAVERVISVE 1015
+P + + E + S +P L + PL + V + + SE ++ V S
Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS 1837
Query: 1016 PLLPRYSPQSLTDP-QIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWS 1074
P++ + S P + I+ ST E T + +P + S L +T A S
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLS--TTPAVTS 1895
Query: 1075 SPV--------APTPSKYTSPPWVTPKFEELYQLSAHPESTT 1108
+PV +PT + +S P TP+ E L++ P STT
Sbjct: 1896 TPVTTYAQVSSSPTTADGSSMPTSTPR-EGRPPLTSIPVSTT 1936
Score = 37.0 bits (84), Expect = 0.16
Identities = 82/358 (22%), Positives = 128/358 (35%), Gaps = 46/358 (12%)
Query: 915 SQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEV---------SS 965
S P+ N T + PT+S GTS+ S E P P V E +S
Sbjct: 893 STPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTS 952
Query: 966 SPKSMAVE--------ESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPL 1017
+P + + E E S+ P PL + V + + SE S
Sbjct: 953 TPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSE-------ASTLST 1005
Query: 1018 LPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPV 1077
P S LT + S EGT + P S P R +M S+E +S +
Sbjct: 1006 TPVDSNTPLTTS--TEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSE-TSTL 1062
Query: 1078 APTPSKYTSPPWVTPKFEELYQLSAHPESTTVEEDISKEQLLPRH----LSQLTVGNKVQ 1133
+ TP+ TS P T + + S + T++ E P ++L V ++
Sbjct: 1063 STTPAD-TSTPVTT--YSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119
Query: 1134 QLSSNFERAAIEADIS--GSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGT----SNKSP 1187
LS+ +I S S P + S E T+ L M V T S +
Sbjct: 1120 TLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT 1179
Query: 1188 IPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPPNLP---SKSLSKPEVKHQVFSDS 1242
+ P S + +E+S+ ++V +P + P S L+ V+H + S
Sbjct: 1180 LSTTPVDSKTQVATS---TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASS 1234
Score = 35.0 bits (79), Expect = 0.63
Identities = 205/1040 (19%), Positives = 352/1040 (33%), Gaps = 129/1040 (12%)
Query: 195 LSSSNINISSLQPVRENQP----TKARAKSSMGSKALSHDSIFMLGPEPERSASKMFPSM 250
++SS + S PV N P T+A + S+ S + G P S +
Sbjct: 641 VASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLV 700
Query: 251 DPQRGRPQQRSHISRTLPKPRSKVPGVVSGAMSGAVLQNVPTSAVWVAGPKITENPPSRR 310
+ + + P S GA ++PTS +T P S+
Sbjct: 701 ASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA---SMPTSTPSEGSTPLTSMPVSKT 757
Query: 311 RRLSIIPPVIQ--PEIISKNLVEISLDDESPKNPQKKALPHKSLTATQSFSELSSGPDCS 368
S + P S ++ + SP + ++P T ++ L+S P
Sbjct: 758 LLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPIS--TPSEGSPLLTSIP--- 812
Query: 369 QSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAARHKMTLNPRKQKKNLQVIIRGLPV 428
S+T + +++ + P+ ++P TT + SS + T P + + +PV
Sbjct: 813 VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPV 872
Query: 429 WFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPLVSEEEKSITK-PKEINEK 487
+ TL T +D PV E + P SE T P E +
Sbjct: 873 STTLVA-------TSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTP 925
Query: 488 KLGMDSADSSSQKQNNKTEMYDKKTTDQA-PNTDASRSQGYPMSAAYGRRWRRKGASVSG 546
M DS++ +++ D + P T ++ + P +A +G S+
Sbjct: 926 LTSMP--DSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTA--------EGTSIPT 975
Query: 547 LSGCEFK--------GRSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPT 598
+ E +L +SE L S T T + S + PT
Sbjct: 976 STPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT-STEASSPPPTAEGTSMPT 1034
Query: 599 TSQPETTTPQGLLSDKDDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAAS 658
++ E +TP + M + + A + P+ S S D S
Sbjct: 1035 STPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTA----DGTS 1090
Query: 659 GAEKTEARASLSLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKAQSK 718
T + S L +ST L V++EA ++ + + S + + +
Sbjct: 1091 MPTSTYSEGSTPLTSVPVSTR-----LVVSSEAST-LSTTPVDTSIPVTTSTEASSSPTT 1144
Query: 719 MESAQDVQTICKE--KPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDA 776
E + E P ++ + T V +T + V +KT S SS P A
Sbjct: 1145 AEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTA 1204
Query: 777 EEVSSDSENIPEEGDGSEELAHGH--------SSQSLGKFEDEQEVFSESKSFVEDLSSS 828
E S + E + H S+ S + V + +++ ++
Sbjct: 1205 EVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE 1264
Query: 829 EEELDLRCLSQA-------------LEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPL 875
L S+ + PE + + T TS++ SSS
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPT---- 1320
Query: 876 RHPAQALGKP-----KNQQEVSSASNNTPEEQNDFMQQLPSRCP---SQPIMNPTVQQQV 927
PA+ P + + ++S NT + + L S P S P+ T
Sbjct: 1321 --PAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISIL-STTPVDNSTPVTTSTEACSS 1377
Query: 928 PTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVS---------SSPKSMAVE----- 973
PT+S GTS+ S+ E P P V E S S+P + + E
Sbjct: 1378 PTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSP 1437
Query: 974 ---ESISMKPLPPKLLCQPLMNPKVQQNMFSGSE--DIAVERVISVEPLLPRYSPQSLTD 1028
E IS+ P PL + V + SE ++ V S P++ + S
Sbjct: 1438 TTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPT 1497
Query: 1029 P-QIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSP 1087
P + I+ ST E T + +P +S + ++S+ST+ +S T S+ +S
Sbjct: 1498 PAEGTSIAISTPSEGSTALTSIP---VSTTTVASSEINSLSTTPAVTSTPVTTYSQASSS 1554
Query: 1088 PWVTPKFEELYQLSAHPESTTVEEDISKEQLL-----PRHLSQLTVGNKVQQLSSNFERA 1142
P T Q S + E +T + +L LS + +K Q +S +
Sbjct: 1555 P--TTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASS 1612
Query: 1143 AIEADIS---------GSPL 1153
+ A+ S GSPL
Sbjct: 1613 STTAEGSSMTISTPSEGSPL 1632
Score = 33.1 bits (74), Expect = 2.4
Identities = 84/393 (21%), Positives = 134/393 (34%), Gaps = 56/393 (14%)
Query: 750 STTAKGDVYAKTLPPRSLFQSSRKPDAEEVSSDSENIP----EEGDGSEELAHGHSSQSL 805
ST ++G ++P + +S + ++ + + P + S A G S Q+
Sbjct: 1507 STPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTS 1566
Query: 806 GKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDD 865
E + S S + +SS L + ++ TE+SS +S
Sbjct: 1567 TYSEGSTPLTSLPVSTMLVVSSEANTLS----TTPIDSKTQVTASTEASSSTTAEGSSMT 1622
Query: 866 CSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQ 925
S+ E PL P E S+ S TP + N P++ T
Sbjct: 1623 ISTPSEGSPLLTSIPVSTTPVASPEASTLST-TPVDSNS------------PVITSTEVS 1669
Query: 926 QVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVS---------SSPKSMAVE--- 973
PT + GTS+ S E P P +S S+P + + E
Sbjct: 1670 SSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARS 1729
Query: 974 -----ESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTD 1028
E SM P PL + V SE + S ++ +
Sbjct: 1730 SPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSS 1789
Query: 1029 PQIRQISESTAVEEGTYVEPLPPRCLSQPSERPKFLDS-----MSTSAEWSSPV------ 1077
P +E T++ T E + P S P +S +T + +SPV
Sbjct: 1790 P---TTAEGTSIPTSTLSEGMTP-LTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845
Query: 1078 --APTPSKYTSPPWVTPKFEELYQLSAHPESTT 1108
+PTP++ TS TP E L++ P STT
Sbjct: 1846 SSSPTPAEGTSIATSTPS-EGSTALTSIPVSTT 1877
Score = 32.7 bits (73), Expect = 3.1
Identities = 52/207 (25%), Positives = 73/207 (35%), Gaps = 32/207 (15%)
Query: 915 SQPIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEV---------SS 965
S P+ T PT++ GTSI S E P P V E +S
Sbjct: 2425 STPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTS 2484
Query: 966 SPKSMAVEESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQS 1025
+P + + E S S P + + P+ + + S ++ V S E +P
Sbjct: 2485 TPMTTSTEASSS--PTTAEDIVVPISTASEGSTLLT-SIPVSTTPVASPEASTLSTTPVD 2541
Query: 1026 LTDPQI--RQISESTAVEEG------TYVEPLPPRCLSQPSERPKFLDSMS----TSAEW 1073
P + +IS S EG TY E P S +P S T +
Sbjct: 2542 SNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDT 2601
Query: 1074 SSPV--------APTPSKYTSPPWVTP 1092
S PV +PT +K TS P TP
Sbjct: 2602 SIPVTTSTETSSSPTTAKDTSMPISTP 2628
Score = 31.6 bits (70), Expect = 6.9
Identities = 78/394 (19%), Positives = 130/394 (32%), Gaps = 71/394 (18%)
Query: 870 EEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLP--------------SRCPS 915
E P+ AQA P E S SN+ P + + ++P S P+
Sbjct: 242 EISTPVTISAQASSSPTTA-EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPA 300
Query: 916 Q---PIMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAV 972
P++ T PT++ GTSI P + P S+ P + +
Sbjct: 301 ATNIPVITSTEASSSPTTAEGTSI----------PTSTYTEGSTPLTSTPASTMPVATSE 350
Query: 973 EESISMKPLPPKLLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSPQSLTDPQIR 1032
++S+ P+ L P + + PL L
Sbjct: 351 MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEA 410
Query: 1033 QISESTAVEEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPWVTP 1092
+ + V+ T+V S+ S P T+AE +S TPS+ ++P
Sbjct: 411 STTSTIPVDSKTFV-----TTASEASSSP-------TTAEDTSIATSTPSEGSTP----- 453
Query: 1093 KFEELYQLSAHPESTTVEEDISKEQLLPRHLSQLTVGNKVQQLSSNFERAAIEADISGSP 1152
L++ P STT ++ + +LS V +K Q +S S
Sbjct: 454 -------LTSMPVSTT---PVASSE--ASNLSTTPVDSKTQVTTST----------EASS 491
Query: 1153 LPPQYATQFLKRSKVQEMTSRLEKMAVE----GTSNKSPIPRRPTQSFVKFMAQQIFSES 1208
PP + S E ++ L M+V +S S + P + S S
Sbjct: 492 SPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSS 551
Query: 1209 SALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDS 1242
S G+ + P+ S L+ V ++ S
Sbjct: 552 STTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 43.9 bits (102), Expect = 0.001
Identities = 57/210 (27%), Positives = 88/210 (41%), Gaps = 29/210 (13%)
Query: 703 EDQEAFSFDLQKAQSKMESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDV---YA 759
ED E F+ + ++A+ + ++ +E+ G V S L + ++ YA
Sbjct: 398 EDDEEFTANEEEAEDEEDTIA-----AEEQLEGEVDHAMELSELAREGELSMEELLQQYA 452
Query: 760 KTLPPRSLFQSSRKPDAEEVSSDSENIPEEG--DGSEELAHGHSSQSLG---KFEDEQEV 814
P S SS D +EV ++S + EG + E SSQS + EDE++
Sbjct: 453 GAYAPGS--GSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDE 510
Query: 815 FSE----SKSFVEDLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSE 870
SE S S + S SEE D + SQA EE ED + E Y + D SE
Sbjct: 511 HSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVE-------YLLARDEEQSE 563
Query: 871 EDLPLRHPA---QALGKPKNQQEVSSASNN 897
D P LG K ++++A+ +
Sbjct: 564 ADAGSGPPTPGPTTLGPKKEITDIAAAAES 593
Score = 32.3 bits (72), Expect = 4.1
Identities = 33/168 (19%), Positives = 70/168 (41%), Gaps = 25/168 (14%)
Query: 763 PPRSLFQSSRKP-----DAEEVSSDSENIPEEGD--GSEELAHGHSSQSL--------GK 807
PP ++ Q +++P D EE +++ E +E D +EE G ++ G+
Sbjct: 382 PPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGE 441
Query: 808 FEDEQEVFSESKSFVEDLSSSEEELDLRCLSQA----------LEEPEDAEVFTESSSYV 857
E+ + + ++ SSE+E + + + EEP + ++S S
Sbjct: 442 LSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVE 501
Query: 858 EKYNTSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDF 905
++ +D S EE+ ++ +++ S + + EE +DF
Sbjct: 502 DRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDF 549
>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
Length = 2472
Score = 43.9 bits (102), Expect = 0.001
Identities = 75/332 (22%), Positives = 133/332 (40%), Gaps = 71/332 (21%)
Query: 555 RSLKQSSEGYGLGDRAGSSPTNKTARNVPFSHLSLEKDNMEQPTTSQPETTTPQGLLSDK 614
++ ++S EG + + N+T V + + L + ME T T +L +
Sbjct: 1312 KNTEESVEGIVVLENNPPGLLNQT-ECVSDNQVHLSESTMEHDNTKLKAATVENAVLLET 1370
Query: 615 DDMGRRNAGIDFGSRKASAAQPIPENMDNSMVSDPQPYHEDAA---SGAEKTEARASL-- 669
+ + +N I+ S+ EN ++S Q +ED+ + +KT R+S
Sbjct: 1371 NTVEEKNVEINLESK---------ENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRR 1421
Query: 670 SLMVESLSTTQEEAILSVAAEAQVFMNPSHIQLEDQEAFSFDLQKA----------QSKM 719
S +VES + +Q++ SH + E ++ LQK+ + K+
Sbjct: 1422 SEVVESTTESQDK-------------ENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKL 1468
Query: 720 ESAQDVQTICKEKPSGNVHQTFTASVLGMTSTTAKGDVYAKTLPPRSLFQSSRKPDAEEV 779
+ Q +Q EK S N+H+ LG TS A+ + Q+ +K
Sbjct: 1469 IAEQTLQENLIEKGS-NLHE----KTLGETSANAETE------------QNKKK------ 1505
Query: 780 SSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFVEDLSSSEEELDLRCLSQ 839
+D ENI EGDG++++ SS+ L + + S+ + + +SE S
Sbjct: 1506 -ADPENIKSEGDGTQDIV-DKSSEKLVRGRTRYQTRRASQGLLSSIENSE--------SD 1555
Query: 840 ALEEPEDAEVFTESSSYVEKYNTSDDCSSSEE 871
+ E E+ S + K N S D EE
Sbjct: 1556 SSEAKEEGSRKKRSGKWKNKSNESVDIQDQEE 1587
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,395,387
Number of Sequences: 37866
Number of extensions: 3671728
Number of successful extensions: 15236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 501
Number of HSP's that attempted gapping in prelim test: 13384
Number of HSP's gapped (non-prelim): 2392
length of query: 1709
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1593
effective length of database: 13,855,062
effective search space: 22071113766
effective search space used: 22071113766
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.