Guide to the Human Genome
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Name: GDF15 Sequence: fasta or formatted (308aa) NCBI GI: 153792495
Description:

growth differentiation factor 15

Referenced in:

TGF-beta Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.7         30           2
 C cysteine            2.9          9           2
 D aspartate           4.5         14           2
 E glutamate           4.5         14           1
 F phenylalanine       1.3          4           1
 G glycine             5.2         16           2
 H histidine           3.9         12           1
 I isoleucine          1.9          6           1
 K lysine              1.6          5           1
 L leucine            14.9         46           2
 M methionine          1.6          5           1
 N asparagine          1.9          6           1
 P proline             8.8         27           3
 Q glutamine           4.5         14           1
 R arginine           11.4         35           3
 S serine              9.4         29           3
 T threonine           4.2         13           1
 V valine              4.9         15           1
 W tryptophan          1.6          5           1
 Y tyrosine            1.0          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   growth differentiation factor 15 
LOC100292463          0.706   PREDICTED: similar to growth differentiation factor...
GDF1                  0.091   growth differentiation factor 1 
BMP6                  0.091   bone morphogenetic protein 6 preproprotein 
BMP5                  0.086   bone morphogenetic protein 5 preproprotein 
BMP7                  0.083   bone morphogenetic protein 7 precursor 
GDF7                  0.083   growth differentiation factor 7 preproprotein 
GDF6                  0.081   growth differentiation factor 6 precursor 
BMP8A                 0.076   bone morphogenetic protein 8A 
BMP8B                 0.076   bone morphogenetic protein 8B preproprotein 
INHBE                 0.075   activin beta E 
GDF9                  0.073   growth differentiation factor 9 precursor 
GDF2                  0.073   growth differentiation factor 2 
GDF5                  0.071   growth differentiation factor 5 preproprotein 
NODAL                 0.070   nodal precursor 
GDF3                  0.063   growth differentiation factor 3 precursor 
TGFB2                 0.061   transforming growth factor, beta 2 isoform 1 
TGFB2                 0.061   transforming growth factor, beta 2 isoform 2 
BMP15                 0.060   bone morphogenetic protein 15 precursor 
BMP4                  0.058   bone morphogenetic protein 4 preproprotein 
BMP4                  0.058   bone morphogenetic protein 4 preproprotein 
BMP4                  0.058   bone morphogenetic protein 4 preproprotein 
TGFB3                 0.058   transforming growth factor, beta 3 
BMP3                  0.056   bone morphogenetic protein 3 preproprotein 
GDF10                 0.055   growth differentiation factor 10 precursor 
TGFB1                 0.055   transforming growth factor, beta 1 
INHBC                 0.055   inhibin beta C chain preproprotein 
BMP2                  0.051   bone morphogenetic protein 2 preproprotein 
INHBA                 0.048   inhibin beta A precursor 
GDF11                 0.047   growth differentiation factor 11 precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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