Guide to the Human Genome
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Name: GDF11 Sequence: fasta or formatted (407aa) NCBI GI: 5031613
Description:

growth differentiation factor 11 precursor

Referenced in:

TGF-beta Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.1         37          13
 C cysteine            3.2         13           2
 D aspartate           4.2         17           1
 E glutamate           6.1         25           2
 F phenylalanine       3.4         14           1
 G glycine             7.6         31           6
 H histidine           3.2         13           1
 I isoleucine          4.4         18           2
 K lysine              4.4         18           1
 L leucine            10.3         42           3
 M methionine          2.2          9           1
 N asparagine          2.2          9           1
 P proline             7.9         32           2
 Q glutamine           5.2         21           2
 R arginine            6.6         27           2
 S serine              6.6         27           2
 T threonine           3.9         16           2
 V valine              5.2         21           2
 W tryptophan          1.7          7           1
 Y tyrosine            2.5         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   growth differentiation factor 11 precursor 
MSTN                  0.564   myostatin 
INHBB                 0.127   inhibin beta B subunit preproprotein 
INHBA                 0.106   inhibin beta A precursor 
INHBC                 0.092   inhibin beta C chain preproprotein 
TGFB2                 0.090   transforming growth factor, beta 2 isoform 2 
TGFB3                 0.090   transforming growth factor, beta 3 
INHBE                 0.090   activin beta E 
BMP6                  0.088   bone morphogenetic protein 6 preproprotein 
TGFB2                 0.088   transforming growth factor, beta 2 isoform 1 
TGFB1                 0.087   transforming growth factor, beta 1 
BMP5                  0.084   bone morphogenetic protein 5 preproprotein 
BMP10                 0.077   bone morphogenetic protein 10 preproprotein 
BMP7                  0.076   bone morphogenetic protein 7 precursor 
GDF7                  0.075   growth differentiation factor 7 preproprotein 
BMP4                  0.073   bone morphogenetic protein 4 preproprotein 
BMP4                  0.073   bone morphogenetic protein 4 preproprotein 
BMP4                  0.073   bone morphogenetic protein 4 preproprotein 
BMP2                  0.072   bone morphogenetic protein 2 preproprotein 
GDF6                  0.072   growth differentiation factor 6 precursor 
GDF5                  0.071   growth differentiation factor 5 preproprotein 
BMP8B                 0.066   bone morphogenetic protein 8B preproprotein 
GDF3                  0.066   growth differentiation factor 3 precursor 
BMP3                  0.065   bone morphogenetic protein 3 preproprotein 
BMP8A                 0.064   bone morphogenetic protein 8A 
GDF10                 0.059   growth differentiation factor 10 precursor 
GDF1                  0.057   growth differentiation factor 1 
BMP15                 0.054   bone morphogenetic protein 15 precursor 
GDF2                  0.051   growth differentiation factor 2 
NODAL                 0.049   nodal precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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