Guide to the Human Genome
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Name: TGFB1 Sequence: fasta or formatted (390aa) NCBI GI: 63025222
Description:

transforming growth factor, beta 1

Referenced in:

TGF-beta Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         24           2
 C cysteine            3.1         12           2
 D aspartate           3.6         14           1
 E glutamate           6.7         26           1
 F phenylalanine       2.6         10           2
 G glycine             5.1         20           2
 H histidine           2.6         10           1
 I isoleucine          3.6         14           1
 K lysine              4.6         18           1
 L leucine            13.3         52           3
 M methionine          1.8          7           1
 N asparagine          3.8         15           2
 P proline             7.7         30           2
 Q glutamine           3.6         14           1
 R arginine            7.7         30           2
 S serine              7.9         31           2
 T threonine           4.4         17           2
 V valine              5.9         23           2
 W tryptophan          1.8          7           1
 Y tyrosine            4.1         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transforming growth factor, beta 1 
TGFB3                 0.376   transforming growth factor, beta 3 
TGFB2                 0.370   transforming growth factor, beta 2 isoform 2 
TGFB2                 0.354   transforming growth factor, beta 2 isoform 1 
MSTN                  0.103   myostatin 
GDF11                 0.091   growth differentiation factor 11 precursor 
INHBA                 0.083   inhibin beta A precursor 
INHBB                 0.073   inhibin beta B subunit preproprotein 
BMP2                  0.071   bone morphogenetic protein 2 preproprotein 
INHBE                 0.069   activin beta E 
BMP6                  0.064   bone morphogenetic protein 6 preproprotein 
BMP7                  0.058   bone morphogenetic protein 7 precursor 
BMP10                 0.058   bone morphogenetic protein 10 preproprotein 
BMP5                  0.056   bone morphogenetic protein 5 preproprotein 
INHBC                 0.056   inhibin beta C chain preproprotein 
BMP4                  0.055   bone morphogenetic protein 4 preproprotein 
BMP4                  0.055   bone morphogenetic protein 4 preproprotein 
BMP4                  0.055   bone morphogenetic protein 4 preproprotein 
GDF1                  0.053   growth differentiation factor 1 
GDF3                  0.049   growth differentiation factor 3 precursor 
BMP8A                 0.049   bone morphogenetic protein 8A 
GDF6                  0.047   growth differentiation factor 6 precursor 
BMP8B                 0.045   bone morphogenetic protein 8B preproprotein 
GDF7                  0.045   growth differentiation factor 7 preproprotein 
GDF15                 0.042   growth differentiation factor 15 
LOC100292463          0.042   PREDICTED: similar to growth differentiation factor...
BMP3                  0.041   bone morphogenetic protein 3 preproprotein 
GDF5                  0.040   growth differentiation factor 5 preproprotein 
NODAL                 0.035   nodal precursor 
GDF2                  0.031   growth differentiation factor 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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