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Search of human proteins with 153791982
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
(560 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens] 1126 0.0
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 1037 0.0
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens] 138 2e-32
gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens] 138 2e-32
gi|110349719 titin isoform N2-A [Homo sapiens] 62 1e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 62 1e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 60 7e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens] 59 1e-08
gi|19924097 synapsin I isoform Ib [Homo sapiens] 59 1e-08
gi|153792074 proline rich 12 [Homo sapiens] 59 1e-08
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 57 3e-08
gi|33356148 formin-like 1 [Homo sapiens] 57 4e-08
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 57 6e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 56 8e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 56 1e-07
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 55 2e-07
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 55 2e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 55 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 54 3e-07
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 54 3e-07
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 54 3e-07
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 54 3e-07
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 54 3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 4e-07
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 54 4e-07
gi|157168329 formin 1 [Homo sapiens] 54 5e-07
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 54 5e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 54 5e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 53 6e-07
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 53 6e-07
>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
Length = 560
Score = 1126 bits (2913), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 1 MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA 60
MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA
Sbjct: 1 MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA 60
Query: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP
Sbjct: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
Query: 121 PEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRF 180
PEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRF
Sbjct: 121 PEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRF 180
Query: 181 GEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP 240
GEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP
Sbjct: 181 GEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP 240
Query: 241 DDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK 300
DDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK
Sbjct: 241 DDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK 300
Query: 301 MYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTT 360
MYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTT
Sbjct: 301 MYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTT 360
Query: 361 VNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQS 420
VNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQS
Sbjct: 361 VNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQS 420
Query: 421 KNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQR 480
KNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQR
Sbjct: 421 KNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQR 480
Query: 481 YRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAGLNKWQLLHQTVTSPAAPLQCLTD 540
YRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAGLNKWQLLHQTVTSPAAPLQCLTD
Sbjct: 481 YRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAGLNKWQLLHQTVTSPAAPLQCLTD 540
Query: 541 HCGFRLGALKLTVKRAAQRH 560
HCGFRLGALKLTVKRAAQRH
Sbjct: 541 HCGFRLGALKLTVKRAAQRH 560
>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
Length = 755
Score = 1037 bits (2682), Expect = 0.0
Identities = 517/517 (100%), Positives = 517/517 (100%)
Query: 1 MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA 60
MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA
Sbjct: 1 MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA 60
Query: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP
Sbjct: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
Query: 121 PEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRF 180
PEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRF
Sbjct: 121 PEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRF 180
Query: 181 GEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP 240
GEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP
Sbjct: 181 GEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP 240
Query: 241 DDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK 300
DDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK
Sbjct: 241 DDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK 300
Query: 301 MYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTT 360
MYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTT
Sbjct: 301 MYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTT 360
Query: 361 VNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQS 420
VNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQS
Sbjct: 361 VNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQS 420
Query: 421 KNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQR 480
KNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQR
Sbjct: 421 KNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQR 480
Query: 481 YRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAG 517
YRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAG
Sbjct: 481 YRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAG 517
>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
Length = 590
Score = 138 bits (347), Expect = 2e-32
Identities = 105/382 (27%), Positives = 181/382 (47%), Gaps = 32/382 (8%)
Query: 159 GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIP----VTVFPKREYKDK 214
G + V ++ ++ ALVV+ GE+ F+G+L+D +K+ G G+P + + D
Sbjct: 6 GCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDS 65
Query: 215 PEAMPLQSNT--FQEGTEVKCEANGAVPDDPS-PVPHPELSLAESLWTSKPPPLFHEGAP 271
P + + Q G+ A G P + + P P P L + P P + EGAP
Sbjct: 66 HGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAP 125
Query: 272 YPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTS--IMNAIKLRPRQVLCDKCKNSV 329
+P PL++RDTY +PQPPPR IKR +R++ R I++ I+LRPRQVLC+KCK+++
Sbjct: 126 FPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTL 185
Query: 330 ----------VAEKKEIRKGSSA-TDSSKYEDKKRRNESVTTVNKKLKTDHKVDGKNQNE 378
A + R GS + K E+ + + ++ K + + + + E
Sbjct: 186 SPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAE 245
Query: 379 SQKRNAVVKVS-NIAHSRGRVVKVSAQANTSKAQLSTKKVLQSKNMDHAKAREVLKIAKE 437
R+ V+K+S + +G VVK+ ++ + S L + Q+ D ++ EVL
Sbjct: 246 QVPRSPVIKISYSTPQGKGEVVKIPSRVHGS---LEPFRPQQAPQDDGSQDPEVL----- 297
Query: 438 KAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSL-PPRVRLKPQRYRNEENDSSLKTGLEK 496
+ + + + K+ TR P+ L PP++RLKP R + E++ + L
Sbjct: 298 DRESRDRPSCAPSASIPKLKLTRPV--PAGADLPPPKIRLKPHRLGDSEHEPVYRAELVG 355
Query: 497 MRSGKMAPKPQSRCTSTRSAGL 518
+G + + C + GL
Sbjct: 356 ELNGYLRDSSPAPCADGPAGGL 377
>gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]
Length = 499
Score = 138 bits (347), Expect = 2e-32
Identities = 105/382 (27%), Positives = 181/382 (47%), Gaps = 32/382 (8%)
Query: 159 GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIP----VTVFPKREYKDK 214
G + V ++ ++ ALVV+ GE+ F+G+L+D +K+ G G+P + + D
Sbjct: 6 GCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDS 65
Query: 215 PEAMPLQSNT--FQEGTEVKCEANGAVPDDPS-PVPHPELSLAESLWTSKPPPLFHEGAP 271
P + + Q G+ A G P + + P P P L + P P + EGAP
Sbjct: 66 HGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAP 125
Query: 272 YPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTS--IMNAIKLRPRQVLCDKCKNSV 329
+P PL++RDTY +PQPPPR IKR +R++ R I++ I+LRPRQVLC+KCK+++
Sbjct: 126 FPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTL 185
Query: 330 ----------VAEKKEIRKGSSA-TDSSKYEDKKRRNESVTTVNKKLKTDHKVDGKNQNE 378
A + R GS + K E+ + + ++ K + + + + E
Sbjct: 186 SPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAE 245
Query: 379 SQKRNAVVKVS-NIAHSRGRVVKVSAQANTSKAQLSTKKVLQSKNMDHAKAREVLKIAKE 437
R+ V+K+S + +G VVK+ ++ + S L + Q+ D ++ EVL
Sbjct: 246 QVPRSPVIKISYSTPQGKGEVVKIPSRVHGS---LEPFRPQQAPQDDGSQDPEVL----- 297
Query: 438 KAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSL-PPRVRLKPQRYRNEENDSSLKTGLEK 496
+ + + + K+ TR P+ L PP++RLKP R + E++ + L
Sbjct: 298 DRESRDRPSCAPSASIPKLKLTRPV--PAGADLPPPKIRLKPHRLGDSEHEPVYRAELVG 355
Query: 497 MRSGKMAPKPQSRCTSTRSAGL 518
+G + + C + GL
Sbjct: 356 ELNGYLRDSSPAPCADGPAGGL 377
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 62.0 bits (149), Expect = 1e-09
Identities = 75/330 (22%), Positives = 125/330 (37%), Gaps = 41/330 (12%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEA 84
PE P E +P + E P+ E + +EP +PPP P PE
Sbjct: 10793 PERAESPPPEVYEEPEEIAPEEEIAPEEEKP--VPVAEEEEPEVPPPAVPEEPKKIIPEK 10850
Query: 85 VGPELEAEEKLSVRVAE--SAAAAPQGGPELPPSPASPPEQP-----------PAPEERE 131
P ++ E + E P+ P PP P +PP++ P + E
Sbjct: 10851 KVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPE 10910
Query: 132 EPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMD 191
+P +P+ V + GG+ V +L+P + + +++ L E ++
Sbjct: 10911 KPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE 10970
Query: 192 LSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVP-DDPSPVPHPE 250
K+ +P PK + + + + E T+V E A+P P P P PE
Sbjct: 10971 KVKK---PAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVP-EIKPAIPLPAPEPKPKPE 11026
Query: 251 LSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTSIM 310
+ T KPPP+ E P P+ + P K+ + K +EE
Sbjct: 11027 AEVK----TIKPPPVEPEPTPIAAPVTV------------PVVGKKAEAKAPKEEAAKPK 11070
Query: 311 NAIKLRPRQVLCDKCKNSVVAEKKEIRKGS 340
IK P+ K + + AE++++R GS
Sbjct: 11071 GPIKGVPK-----KTPSPIEAERRKLRPGS 11095
Score = 52.0 bits (123), Expect = 1e-06
Identities = 96/475 (20%), Positives = 176/475 (37%), Gaps = 83/475 (17%)
Query: 22 EAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP--PPPPGELA 79
+ EP +P E P+P VP E P+ + P+P P P +
Sbjct: 9308 KVEPPAPKVP--EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKK 9365
Query: 80 RSPEAVGPELE----AEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPL 135
+P A PE++ EEK+++ V + + P PE+P + PEER+ P
Sbjct: 9366 EAPPAKVPEVQKGVVTEEKITI-VTQREESPPPAVPEIP--------KKKVPEERKPVPR 9416
Query: 136 ------PQPVAPALVPPAGGDSTVSQLIPGSE------VRVTLDHIIEDALVVSFRFGEK 183
P P PAL + V+ +P ++ V+ ++E+ V+ EK
Sbjct: 9417 KEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVA---EEK 9473
Query: 184 LFSGVLM-------------DLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTE 230
L V + S G+ ++V+ + E +++ EA + +E E
Sbjct: 9474 LSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEE 9533
Query: 231 VKCEANGAVPD---DPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIP 287
E + + P E + + K P E PPP + + + +P
Sbjct: 9534 YVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEE----PPPAKVPEAPKKIVP 9589
Query: 288 Q-----PPPRKIKRPKRKMYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKK-------- 334
+ P P+K K P K+ EEP + K+ P+ + ++ + V E+
Sbjct: 9590 EKKVPAPVPKKEKVPPPKV-PEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEK 9648
Query: 335 ---EIRKGSSATDSSKYEDKKRRNESVTTVNKKLKTDHKVDGKNQNESQKRNAVVKVSNI 391
+ K + + E+ KR + K K + + K ++ R VVK
Sbjct: 9649 VLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAK---VTEFRKRVVKEE-- 9703
Query: 392 AHSRGRVVKVSAQANTSKAQ-LSTKKVLQSKNMDHAKAREVLKIAKEKAQKKQNE 445
KVS +A + Q + +++ K + E + + +E+ ++ E
Sbjct: 9704 --------KVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEE 9750
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/262 (24%), Positives = 95/262 (36%), Gaps = 37/262 (14%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPP-------------PPP 75
P+ E P+P VP ++ AP A P +P P PPP
Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPK-----KKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPP 10001
Query: 76 GELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQP-PAPEEREEPP 134
++ P+ PE EK+ V V + A P PE+P P + P PAP++ E PP
Sbjct: 10002 AKVPEVPKKPVPE----EKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPP 10057
Query: 135 LPQPVAP-ALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLS 193
P P L+P + V + + +V V + E LF ++
Sbjct: 10058 AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE 10117
Query: 194 KRFGPHGIPVTVFPKRE--YKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPEL 251
+ V P+ E ++ E +P + E E+ E VP + VP E
Sbjct: 10118 E----------VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEE-EVPPEEEYVPEEEE 10166
Query: 252 SLAESLWTSKPPPLFHEGAPYP 273
+ E + P AP P
Sbjct: 10167 FVPEEEVLPEVKPKVPVPAPVP 10188
Score = 50.1 bits (118), Expect = 5e-06
Identities = 73/345 (21%), Positives = 123/345 (35%), Gaps = 81/345 (23%)
Query: 22 EAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP--PPPPPGELA 79
E P E +P + P EA P ++ P+ P PP P PP ++
Sbjct: 10497 EVLPPKEVVPEKKVPVPP--AKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP 10554
Query: 80 RSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPS---PASPPEQ--------PPAPE 128
P+A PE + E + + P+ E+ P PA+PP++ P AP+
Sbjct: 10555 EVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK 10614
Query: 129 E---REEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLF 185
E ++ P+P P P VPP +P +V
Sbjct: 10615 EVVPEKKVPVPPPKKPE-VPPTKVPEVPKVAVPEKKV----------------------- 10650
Query: 186 SGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGA-VPDDPS 244
P IP KPE+ P F+E EV E A V ++P
Sbjct: 10651 ------------PEAIP----------PKPESPP--PEVFEEPEEVALEEPPAEVVEEPE 10686
Query: 245 PVPHPELSL-AESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSI------------PQPPP 291
P P++++ + K P P PP+ + + + + P+ PP
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPP 10746
Query: 292 RKIKRPKRKMYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEI 336
K+ +++ E+ ++ ++ P +V + K V+ EK +
Sbjct: 10747 AKVPEVPKEVVPEKKVAVPKKPEVPPAKV-PEVPKKPVLEEKPAV 10790
Score = 43.9 bits (102), Expect = 4e-04
Identities = 79/300 (26%), Positives = 111/300 (37%), Gaps = 52/300 (17%)
Query: 70 PPPPPPGELA--RSPEAVGPE----LEAEEKLSVRVAESAAAAPQGGPE-LPPS------ 116
PP PP ++ + P A PE + EEK VRV E P PE LPP
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEK--VRVPEEPRVPPTKVPEVLPPKEVVPEK 10508
Query: 117 -----PASPPEQPP-----APEE---REEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVR 163
PA PE PP AP+E ++ P+P P P VPP +P +V
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE-VPPTKVPEVPKAAVPEKKVP 10567
Query: 164 VTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPVTV--FPKREYKDKPEAMPLQ 221
+ E +++ + + P PV V PK +K +P
Sbjct: 10568 EAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPP 10627
Query: 222 SNTFQEGTEVKCEANGAVPDDPSP---VPHPELSLAESLWTSKPPPLFHEG---APYPPP 275
T+V AVP+ P P PE S PP +F E A PP
Sbjct: 10628 KKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPE---------SPPPEVFEEPEEVALEEPP 10678
Query: 276 LFIRDTYNQSIPQPPPRKIKRPKRKM-YREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKK 334
+ + P PP+ PK+ + ++ P + +L P +V + VV EKK
Sbjct: 10679 ---AEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKV--PEVPKEVVPEKK 10733
Score = 42.0 bits (97), Expect = 0.001
Identities = 81/376 (21%), Positives = 135/376 (35%), Gaps = 28/376 (7%)
Query: 26 EMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAV 85
E P E +P VP P+ EP P P E E +
Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEI 10113
Query: 86 GPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAP--AL 143
PE E + + E P+ LP PPE+ P E E P + P +
Sbjct: 10114 VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV 10173
Query: 144 VPPAGGDSTVSQLIPGSEVRVTLDHII----EDALVVSFRFGEKLFSGVLMDLSKRFGPH 199
+P V +P + +VT ++ E+A K + L K
Sbjct: 10174 LPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVL 10233
Query: 200 GIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCE-----ANGAVPDDPSPVPH----PE 250
+ VT P+ E E +P + + +E EV AVP+ P+PVP P
Sbjct: 10234 PVEVTEEPEEE-PISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPP 10292
Query: 251 LSLAESLWTSKPPPLFH--EGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTS 308
+++ + K P E P P + + + P + K + EE S
Sbjct: 10293 AKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVS 10352
Query: 309 IMNAIKLRPRQVLCDKCKNSVV-AEKKEIRKGSSATDSSKYEDKKRRNESVTTVNKKLKT 367
+ R V+ ++ + VV AE +EI + + +Y ++ +E V + +K
Sbjct: 10353 ----VAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHE----VEEFIKL 10404
Query: 368 D-HKVDGKNQNESQKR 382
+ H+V+ +++ E R
Sbjct: 10405 EQHRVEEEHRVEKVHR 10420
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/323 (21%), Positives = 115/323 (35%), Gaps = 65/323 (20%)
Query: 24 EPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPE 83
EPE EPI E +P + E P P+ + +P P P + +P
Sbjct: 10240 EPEEEPISEEEIPEEPPSIEEVEEVAP-------PRVPEVIKKAVPEAPTPVPKKVEAPP 10292
Query: 84 AVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQP-PAPEEREEPPLPQPVAPA 142
A K+S ++ E P E P PA PE P PE++ P +
Sbjct: 10293 A---------KVSKKIPEEKVPVPVQKKEAP--PAKVPEVPKKVPEKKVLVPKKE----- 10336
Query: 143 LVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIP 202
VPPA G + + + + + +VV R ++ + ++ + H +
Sbjct: 10337 AVPPAKGRTVLEEKVSVA---------FRQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387
Query: 203 VTVFPKREYKDKPEAMPLQSNTFQEGTEV----------KCEANGAVPDDPSPVPHPELS 252
F + E+ + E + L+ + +E V + E +P PE+S
Sbjct: 10388 -EYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEIS 10446
Query: 253 LAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIP-QPPPRKIKRPKRKMYREEPTSIMN 311
E + K PP + +P + PP K+ +K+ EE +
Sbjct: 10447 --EKIIPPKKPP------------------TKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486
Query: 312 AIKLRPRQVLCDKCKNSVVAEKK 334
++ P +V VV EKK
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKK 10509
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/131 (29%), Positives = 49/131 (37%), Gaps = 7/131 (5%)
Query: 16 GEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP-PPPPP 74
GE + PE +P P E + E P E + + +P +P PPPP
Sbjct: 10928 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE---PKKLEKVKKPAVPEPPPPK 10984
Query: 75 PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSP-ASPPEQPPAPEEREEP 133
P E P E + E +V E A P PE P P A P P E E
Sbjct: 10985 PVEEVEVPTVTKRERKIPE--PTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT 11042
Query: 134 PLPQPVAPALV 144
P+ PV +V
Sbjct: 11043 PIAAPVTVPVV 11053
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 15/89 (16%)
Query: 57 QQSAPQADEP-PLP----PPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGP 111
++ AP+ P P+P PP P E+ + P EEK V V + AAP P
Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP-------EEKKPVPVPKKEPAAPPKVP 9345
Query: 112 ELPPSPASPPEQPPAP--EEREEPPLPQP 138
E+P P P E+ P P +++E PP P
Sbjct: 9346 EVPKKPV-PEEKIPVPVAKKKEAPPAKVP 9373
Score = 37.7 bits (86), Expect = 0.028
Identities = 75/325 (23%), Positives = 116/325 (35%), Gaps = 50/325 (15%)
Query: 24 EPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARS-- 81
EP +P EA +P A VP E P+ + P+P PP +
Sbjct: 9574 EPPPAKVP--EAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEP 9631
Query: 82 -PEAVGP---ELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQ--PPAPEEREEPPL 135
P V ++ EEK+ V V + A PE P A P E+ P+ EEPP
Sbjct: 9632 LPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPE-EPKRAVPEEKVLKLKPKREEEPPA 9690
Query: 136 PQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKR 195
V + VS P E + + I + ++ E+ S + +
Sbjct: 9691 KVTEFRKRVVK---EEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEE 9747
Query: 196 FGPHGIPV--TVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPV-PHPELS 252
+ + P EY E + ++E E E P+ P PV P PE
Sbjct: 9748 YEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITE-----PEKPIPVKPVPE-- 9800
Query: 253 LAESLWTSKPPPLFHEGAPYPPPLFI--RDTYNQSIPQPPPRKIKRPKRKMYREEPTSIM 310
+P P P PP + + + +P P P+K+K P K+ E
Sbjct: 9801 --------EPVPT----KPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE------ 9842
Query: 311 NAIKLRPRQVLCDKCKNSVVAEKKE 335
P++V +K + S+ +KE
Sbjct: 9843 ------PKKVFEEKIRISITKREKE 9861
Score = 37.4 bits (85), Expect = 0.037
Identities = 54/262 (20%), Positives = 94/262 (35%), Gaps = 44/262 (16%)
Query: 65 EPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQP 124
E P+P P P P P+ + L V E P PP P P E
Sbjct: 9790 EKPIPVKPVP-----EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPK 9844
Query: 125 PAPEE--------REEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVR--VTLDHIIEDAL 174
EE RE+ + +P A + P + +P EV V + + ++
Sbjct: 9845 KVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELE 9904
Query: 175 VVSFRFGEKLFSGV---LMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEV 231
F E++ + V L++ + + + + E+ + E +P+ +V
Sbjct: 9905 PEEVAFEEEVVTHVEEYLVEEEEEY--------IHEEEEFITEEEVVPVIP------VKV 9950
Query: 232 KCEANGAVPDDPSPVPHPELSLAESLWTSKPPPLFHEGAPY-------PPPLFIRDTYNQ 284
VP++ PVP P+ A + P E P PPP + + +
Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKK 10010
Query: 285 SIPQ-----PPPRKIKRPKRKM 301
+P+ P P+K++ P K+
Sbjct: 10011 PVPEEKVPVPVPKKVEAPPAKV 10032
Score = 36.2 bits (82), Expect = 0.082
Identities = 45/205 (21%), Positives = 76/205 (37%), Gaps = 24/205 (11%)
Query: 77 ELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPE----------QPPA 126
E++ + V E+ EEK+ V +++ P+ PELP PA P E +PPA
Sbjct: 9256 EVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKV-PELPEKPA-PEEVAPVPIPKKVEPPA 9313
Query: 127 PEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFS 186
P+ E P P P VP + +P V + E+ + V ++
Sbjct: 9314 PKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP----EVPKKPVPEEKIPVPVAKKKEAPP 9369
Query: 187 GVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDP--- 243
+ ++ K +T+ +RE P + E + VP P
Sbjct: 9370 AKVPEVQKGVVTEE-KITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVP 9428
Query: 244 ----SPVPHPELSLAESLWTSKPPP 264
PVP ++++ + PPP
Sbjct: 9429 ALPKKPVPEEKVAVPVPVAKKAPPP 9453
Score = 35.8 bits (81), Expect = 0.11
Identities = 31/125 (24%), Positives = 48/125 (38%), Gaps = 7/125 (5%)
Query: 17 EGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP--PPP 74
E A E E+ P + L + + E +Q +P +P PP
Sbjct: 9517 EEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPP 9576
Query: 75 PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPP 134
P ++ +P+ + PE +K+ V + P PE P P + PP + EE P
Sbjct: 9577 PAKVPEAPKKIVPE----KKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE-P 9631
Query: 135 LPQPV 139
LP V
Sbjct: 9632 LPAKV 9636
Score = 35.0 bits (79), Expect = 0.18
Identities = 51/235 (21%), Positives = 79/235 (33%), Gaps = 29/235 (12%)
Query: 83 EAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPA 142
E V +E E V V E A P+G PE+ P + P R+EPP P P
Sbjct: 10416 EKVHRVIEVFEAEEVEVFEKPKAPPKG-PEISEKIIPPKKPPTKVVPRKEPPAKVPEVP- 10473
Query: 143 LVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIP 202
+++ +VRV + + V +++ + + P P
Sbjct: 10474 -----------KKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPP 10522
Query: 203 --VTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPD-------------DPSPVP 247
V PK +K +P T+V AVP+ P VP
Sbjct: 10523 PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVP 10582
Query: 248 HPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTY-NQSIPQPPPRKIKRPKRKM 301
+ PP E P P ++ + +P PPP+K + P K+
Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV 10637
Score = 32.0 bits (71), Expect = 1.5
Identities = 33/126 (26%), Positives = 48/126 (38%), Gaps = 29/126 (23%)
Query: 22 EAEPEMEP--IPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELA 79
E + E++P IP S +P+ A VP E P PP+P P P E
Sbjct: 8927 EIKLELKPPDIPDSRVPIPTMPIRA----VPPEEI------PPVVAPPIPLLLPTPEEKK 8976
Query: 80 RSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPV 139
P+ + +A +K + +V A P E P E ++PP P +
Sbjct: 8977 PPPKRIEVTKKAVKKDAKKVV-----------------AKPKEMTPREEIVKKPPPPTTL 9019
Query: 140 APALVP 145
PA P
Sbjct: 9020 IPAKAP 9025
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 62.0 bits (149), Expect = 1e-09
Identities = 45/137 (32%), Positives = 55/137 (40%), Gaps = 35/137 (25%)
Query: 44 ATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELA-----RSPEAV------------- 85
AT + P +A A PP P PPPPP +A R+P A
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
Query: 86 --GPELEAEEKLSV---RVAESAAAAPQGGPELPPSPA--------SPPEQPPAPEEREE 132
GP + L+ A A AP GP P PA PP QPPAP ++++
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225
Query: 133 PPLPQPVAPALVPPAGG 149
PP PQP PP GG
Sbjct: 226 PPPPQPQP----PPEGG 238
Score = 46.2 bits (108), Expect = 8e-05
Identities = 38/119 (31%), Positives = 40/119 (33%), Gaps = 34/119 (28%)
Query: 5 AAEAAATAA-SPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQA 63
AA AAATA SPG G P+ A P P + P G A A
Sbjct: 151 AAAAAATAPPSPGPAQPGPRAQRAAPL----AAPPPAPAAPPAVAPPAGPRRAPPPAVAA 206
Query: 64 DEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPE 122
EPPLPPPP PP A PQ PP P PPE
Sbjct: 207 REPPLPPPPQPP-----------------------------APPQQQQPPPPQPQPPPE 236
Score = 30.8 bits (68), Expect = 3.4
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 10/81 (12%)
Query: 89 LEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPA-------PEEREEPPLPQPV-- 139
L K S+ +A P PP+P P PA P PP P PV
Sbjct: 83 LRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAA 142
Query: 140 -APALVPPAGGDSTVSQLIPG 159
APA P A + + PG
Sbjct: 143 AAPARAPRAAAAAATAPPSPG 163
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 59.7 bits (143), Expect = 7e-09
Identities = 49/160 (30%), Positives = 64/160 (40%), Gaps = 18/160 (11%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQ--QSAPQADEPPLPP-- 70
P +GG +P+ P PG G P + P G+ G Q Q PP PP
Sbjct: 61 PPQGGN---KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 117
Query: 71 ---PPPPPGELARSP----EAVGPELEAEEKLSVRV--AESAAAAPQGG--PELPPSPAS 119
PPP G + P + GP + ++ S R + PQGG P+ PP P
Sbjct: 118 PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 177
Query: 120 PPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPG 159
P+ PP ++ P P P PP G S SQ PG
Sbjct: 178 KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Score = 56.2 bits (134), Expect = 8e-08
Identities = 48/154 (31%), Positives = 64/154 (41%), Gaps = 31/154 (20%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQ--QSAPQADEPPLPP-- 70
P +GG +P+ P PG G P + + P G+ G Q Q PP PP
Sbjct: 183 PPQGGK---KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK 239
Query: 71 ---PPPPPGELARSP----EAVGPELEAEEKLSVRVAESAAAAPQGGPELPP-----SPA 118
PPP G + P + GP + K +A +P G P+ PP +P
Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK------SQSARSPPGKPQGPPQQEGNNPQ 293
Query: 119 SPPEQPPA---PEEREEPPLPQPVAPALVPPAGG 149
PP PPA P++ + PP QP P PP GG
Sbjct: 294 GPP--PPAGGNPQQPQAPPAGQPQGPPR-PPQGG 324
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/145 (27%), Positives = 57/145 (39%), Gaps = 15/145 (10%)
Query: 17 EGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP----- 71
+G +P+ P G ++ + P + P G Q P +P PPP
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
Query: 72 ---PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG--PELPPSPASPPEQPPA 126
PPPPG+ P+ P+ + + PQGG P+ PP P P+ PP
Sbjct: 190 PQGPPPPGK----PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP- 244
Query: 127 PEEREEPPLPQPVAPALVPPAGGDS 151
P+ +P P P PPA G S
Sbjct: 245 PQGGNKPQGPPPPGKPQGPPAQGGS 269
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/127 (29%), Positives = 49/127 (38%), Gaps = 20/127 (15%)
Query: 47 ASVPDGETDGQQSAPQADEPPL-----PPP--------PPPPGELARSPEAVGPELEAEE 93
A P G + + PQ PP PPP PPPPG+ P+ P+ +
Sbjct: 33 AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK----PQGPPPQGDKSR 88
Query: 94 KLSVRVAESAAAAPQGG--PELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDS 151
+ PQGG P+ PP P P+ PP P+ P P P PP GD
Sbjct: 89 SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNRPQGPPPPGKPQGPPPQGDK 147
Query: 152 TVSQLIP 158
+ S P
Sbjct: 148 SRSPRSP 154
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 81 SPEAVGPELEAEEKLSVRVAESAAAAPQGG--PELPPSPASPPEQPPAPEEREEPPLPQP 138
S + + ++ EE S+ +PQGG P+ PP P P+ PP P+ +P P P
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP-PQGGNKPQGPPP 73
Query: 139 VAPALVPPAGGDSTVSQLIP 158
PP GD + S P
Sbjct: 74 PGKPQGPPPQGDKSRSPRSP 93
Score = 31.2 bits (69), Expect = 2.6
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 15 PGEGGA----GEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP 70
P +GG+ + P P + G +P P G Q AP A +P PP
Sbjct: 264 PAQGGSKSQSARSPPGKPQGPPQQEGNNP-----QGPPPPAGGNPQQPQAPPAGQPQGPP 318
Query: 71 PPPPPGELARSPE 83
PP G +R P+
Sbjct: 319 RPPQGGRPSRPPQ 331
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/137 (29%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 20 AGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELA 79
+G P P+P P + P + G+QS P A P PP PP +
Sbjct: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS 553
Query: 80 RSPEAVGPELEAEEKLSVRVAESAAAAPQGG------PELPPSPASPPEQ--PPAPEERE 131
+A P+ + +S A+ AP GG P+ PP PA P Q P R
Sbjct: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613
Query: 132 EPPLPQPVAPALVPPAG 148
PP Q P+ PAG
Sbjct: 614 GPPTTQQPRPSGPGPAG 630
Score = 52.8 bits (125), Expect = 8e-07
Identities = 74/294 (25%), Positives = 97/294 (32%), Gaps = 37/294 (12%)
Query: 13 ASPGEGGAGEAEPEMEPIP-GSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
ASPG G G+ P +P G + P A + P G PQ PPL
Sbjct: 426 ASPGRGSHGQT-PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQR 484
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEERE 131
PPP G+ S +GP A L R+ +P P+ P S A+PP Q + R
Sbjct: 485 PPPQGQQHLS--GLGP--PAGSPLPQRL-----PSPTSAPQQPASQAAPPTQGQGRQSR- 534
Query: 132 EPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMD 191
P P AP P S Q P R T VS K
Sbjct: 535 -PVAGGPGAPPAARPPASPSPQRQAGPPQATRQT---------SVSGPAPPKASGAPPGG 584
Query: 192 LSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPEL 251
++ P P P R+ T Q+ P P P P+
Sbjct: 585 QQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPR----------PSGPGPAGRPKP 634
Query: 252 SLAESLWTSKPPP-LFHEGAPYPPPL----FIRDTYNQSIPQPPPRKIKRPKRK 300
LA+ PPP G P P L + + +N P PP + + + K
Sbjct: 635 QLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVK 688
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 25/149 (16%)
Query: 2 AAVAAEAAATAASPGEGGAGE---AEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQ 58
AA + + P GG G A P P P +AG P + SV
Sbjct: 522 AAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP---PQATRQTSVSGPAPPKAS 578
Query: 59 SAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPA 118
AP + PP PPG GP R A A P+ G PP+
Sbjct: 579 GAPPGGQQRQGPPQKPPG-------PAGP---------TRQASQAGPVPRTG---PPTTQ 619
Query: 119 SPPEQPPAPEEREEPPLPQPVAPALVPPA 147
P P P R +P L Q + + PPA
Sbjct: 620 QPRPSGPGPAGRPKPQLAQKPSQDVPPPA 648
Score = 31.2 bits (69), Expect = 2.6
Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 70 PPPPPPGELARSPEAV-GPELEAEEKLSVRVAESAAAAPQGG 110
PPPPPPG A SP A GP E+ S ++ AAP G
Sbjct: 30 PPPPPPG--AHSPGATPGPGTATAERSSGVAPAASPAAPSPG 69
Score = 30.4 bits (67), Expect = 4.5
Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 19/118 (16%)
Query: 6 AEAAATAASPGEGGAGEAEPEMEPIPG------SEAGTDPLPVTA---TEASVPDGETDG 56
A A+ A PG G + P+ P P S+AG P+P T T+ P G
Sbjct: 573 APPKASGAPPG-GQQRQGPPQKPPGPAGPTRQASQAG--PVPRTGPPTTQQPRPSGPGPA 629
Query: 57 QQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELP 114
+ PQ + P PPP A P P+L + L+ +A P+ P P
Sbjct: 630 GRPKPQLAQKPSQDVPPPATAAAGGPP--HPQLNKSQSLT-----NAFNLPEPAPPRP 680
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/137 (29%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 20 AGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELA 79
+G P P+P P + P + G+QS P A P PP PP +
Sbjct: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS 553
Query: 80 RSPEAVGPELEAEEKLSVRVAESAAAAPQGG------PELPPSPASPPEQ--PPAPEERE 131
+A P+ + +S A+ AP GG P+ PP PA P Q P R
Sbjct: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613
Query: 132 EPPLPQPVAPALVPPAG 148
PP Q P+ PAG
Sbjct: 614 GPPTTQQPRPSGPGPAG 630
Score = 51.6 bits (122), Expect = 2e-06
Identities = 48/159 (30%), Positives = 60/159 (37%), Gaps = 23/159 (14%)
Query: 13 ASPGEGGAGEAEPEMEPIP-GSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
ASPG G G+ P +P G + P A + P G PQ PPL
Sbjct: 426 ASPGRGSHGQT-PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQR 484
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQ-------- 123
PPP G+ S +GP A L R+ +P P+ P S A+PP Q
Sbjct: 485 PPPQGQQHLS--GLGP--PAGSPLPQRL-----PSPTSAPQQPASQAAPPTQGQGRQSRP 535
Query: 124 ----PPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
P AP P P P A P A ++VS P
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAP 574
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 25/149 (16%)
Query: 2 AAVAAEAAATAASPGEGGAGE---AEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQ 58
AA + + P GG G A P P P +AG P + SV
Sbjct: 522 AAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP---PQATRQTSVSGPAPPKAS 578
Query: 59 SAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPA 118
AP + PP PPG GP R A A P+ G PP+
Sbjct: 579 GAPPGGQQRQGPPQKPPG-------PAGP---------TRQASQAGPVPRTG---PPTTQ 619
Query: 119 SPPEQPPAPEEREEPPLPQPVAPALVPPA 147
P P P R +P L Q + + PPA
Sbjct: 620 QPRPSGPGPAGRPKPQLAQKPSQDVPPPA 648
Score = 31.2 bits (69), Expect = 2.6
Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 70 PPPPPPGELARSPEAV-GPELEAEEKLSVRVAESAAAAPQGG 110
PPPPPPG A SP A GP E+ S ++ AAP G
Sbjct: 30 PPPPPPG--AHSPGATPGPGTATAERSSGVAPAASPAAPSPG 69
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 58.9 bits (141), Expect = 1e-08
Identities = 82/291 (28%), Positives = 111/291 (38%), Gaps = 50/291 (17%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGEL------ 78
P++ P S A + P P +A++ V E + APQ PP PPPPP P +L
Sbjct: 799 PQLLPSVLSHAPS-PSP-SASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRS 856
Query: 79 -ARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPE-LPPSPASPPEQPPAPEEREEPPLP 136
P A P L EE L A G E LPP+P PP E ++
Sbjct: 857 HGLEPAAPSPRLRPEESLD---PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDP---- 909
Query: 137 QPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRF 196
A A P+ + + +P + + D +++D F E++F G D +
Sbjct: 910 ---AGAYRSPSPQGTKAPRFVPLTSICFP-DSLLQDEERSFFPTMEEMFGGGAADDYGKA 965
Query: 197 GPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKC--EANGAVPDDP----SPVPHPE 250
GP P+ E K A P + C A+GA P+ P P PE
Sbjct: 966 GP--------PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017
Query: 251 LSL---AESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPK 298
L AE L + P H+ AP PPP P PPP PK
Sbjct: 1018 LPSTVNAEPLGLIQSGP--HQAAPPPPP----------PPPPPPAPASEPK 1056
Score = 54.3 bits (129), Expect = 3e-07
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 17/146 (11%)
Query: 3 AVAAEAAATAASPGEGGAGEAEPEMEPIPGSEA--GTDPLPVTATEASVPDGETDGQQSA 60
++++ +A P G + P+ P+ + A G PLP +P ++G
Sbjct: 1397 SISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLP------GLPSANSNGTPEP 1450
Query: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
P +E P P PPP P + P P A VA + ++ P P LPP P P
Sbjct: 1451 PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP--PPLPPPP--P 1506
Query: 121 PEQPPAPEEREEPPLPQPVAPALVPP 146
P P P PP P AP PP
Sbjct: 1507 PAMPSPP-----PPPPPAAAPLAAPP 1527
Score = 38.1 bits (87), Expect = 0.022
Identities = 36/121 (29%), Positives = 48/121 (39%), Gaps = 11/121 (9%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPP--PGELARS- 81
P ME + G A D +A P+ E D + A PP P P PG + +
Sbjct: 948 PTMEEMFGGGAADD-----YGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAG 1002
Query: 82 PEAVGPELEAEE--KLSVRVAESAAAAPQGGP-ELPPSPASPPEQPPAPEEREEPPLPQP 138
PE G L+ + +L V Q GP + P P PP PPAP + L P
Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Query: 139 V 139
+
Sbjct: 1063 I 1063
Score = 35.8 bits (81), Expect = 0.11
Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 15/74 (20%)
Query: 10 ATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP 69
A+ A P G G +P P S +PL + QS P PP P
Sbjct: 998 ASGAGPETPGLG-LDPNKPPELPSTVNAEPLGLI--------------QSGPHQAAPPPP 1042
Query: 70 PPPPPPGELARSPE 83
PPPPPP A P+
Sbjct: 1043 PPPPPPPAPASEPK 1056
Score = 35.4 bits (80), Expect = 0.14
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 28/101 (27%)
Query: 58 QSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPEL---- 113
Q+ P PP PPPPP L + L + +AAAA Q P+L
Sbjct: 223 QTPPYRPGPPDPPPPP-------------RHLPTQFNLLASSSAAAAAAEQSSPQLYNFS 269
Query: 114 PPSPASPPEQPPAPEE-----------REEPPLPQPVAPAL 143
+P PP + P + +PP P P A AL
Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHAL 310
Score = 35.4 bits (80), Expect = 0.14
Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 9/99 (9%)
Query: 14 SPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPP- 72
+P + +P P P A P P+ A S P P PP PPPP
Sbjct: 1460 TPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPA 1519
Query: 73 ------PPPGELARSPEAVGPELEAEEKLSVRVAESAAA 105
PP A SPE PEL L + + AA
Sbjct: 1520 AAPLAAPPEEPAAPSPE--DPELPDTRPLHLAKKQETAA 1556
Score = 34.7 bits (78), Expect = 0.24
Identities = 37/151 (24%), Positives = 55/151 (36%), Gaps = 22/151 (14%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPE 88
P+P +G PV+A +S P + P+ E PP PE PE
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPE 1730
Query: 89 LEA------EEKLSVRV--------AESAAAAPQGGPEL-----PPSPASPPEQPPAPEE 129
+ +EK +V E A + Q PE P+ + P+ P +
Sbjct: 1731 KPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVK 1790
Query: 130 REEPPLPQPVAPALVPPAGGDSTVSQLIPGS 160
E PP + + AGG++T PGS
Sbjct: 1791 AEPPPKKR---KKWLKEAGGNATAGGGPPGS 1818
Score = 33.5 bits (75), Expect = 0.53
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 243 PSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPP 291
P P P P L A S T +PP L + P PPP T P PPP
Sbjct: 1431 PGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP---APTPQPQPPPPPP 1476
Score = 32.3 bits (72), Expect = 1.2
Identities = 47/167 (28%), Positives = 55/167 (32%), Gaps = 33/167 (19%)
Query: 6 AEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQ-AD 64
A A AT + G GGAG PG G L A G+ AP +
Sbjct: 424 AAAYATGKASGAGGAGGQAYS----PGQPQGL--LGPQAYGQGFGGGQAQDLSKAPSYSG 477
Query: 65 EPPLPPPPPPPGELAR----SPEAVGPEL-------------------EAEEKLSVRVAE 101
PP PP PPP LA SP+ + +L A LS
Sbjct: 478 GPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGH 537
Query: 102 SAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAG 148
S A + GG P S E P+ R PL P A P G
Sbjct: 538 SPALSGHGGGWGPSSLGGGGEASPSHIIR---PLQSPPATGRPPGVG 581
Score = 30.4 bits (67), Expect = 4.5
Identities = 29/100 (29%), Positives = 34/100 (34%), Gaps = 6/100 (6%)
Query: 58 QSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSP 117
QS P PP P PG+ S A P L S G EL P
Sbjct: 569 QSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGP 628
Query: 118 ASPPEQPPAPEEREEPPLPQPVAPALVPP--AGGDSTVSQ 155
PPA +E L Q + A PP +G D V +
Sbjct: 629 GG----PPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGE 664
Score = 30.0 bits (66), Expect = 5.9
Identities = 17/52 (32%), Positives = 22/52 (42%), Gaps = 6/52 (11%)
Query: 240 PDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPP 291
P P P P P+ +L PPPL PPP + ++P PPP
Sbjct: 1469 PQPPPPPPPPQPALPS------PPPLVAPTPSSPPPPPLPPPPPPAMPSPPP 1514
Score = 29.3 bits (64), Expect = 10.0
Identities = 29/108 (26%), Positives = 43/108 (39%), Gaps = 11/108 (10%)
Query: 30 IPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPP-PPPGELARSPEAVGPE 88
I G+ G+ P ++ ++ + G + P L PP PP SP V
Sbjct: 132 ISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDV-LH 190
Query: 89 LEAEEKLSV-------RVAESAAAAPQG-GP-ELPPSPASPPEQPPAP 127
L+ + +V R+A P G GP + PP PP+ PP P
Sbjct: 191 LKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
Score = 29.3 bits (64), Expect = 10.0
Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 20/124 (16%)
Query: 4 VAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQA 63
+A+ +AA AA A ++ P++ G+ G P E ++P +T + A
Sbjct: 248 LASSSAAAAA------AEQSSPQLYNFSGAAPGPPP-----PERALPRQDTVIKHYQRPA 296
Query: 64 DEPPLPPPPPPPGELARSPEAVGPELEAEEKL-SVRVAESAAAAPQGGPELPPSPASPPE 122
P PPPPP A+ L S+ + A +P GG E P P +
Sbjct: 297 SAQPPPPPPP--------AHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSK 348
Query: 123 QPPA 126
P+
Sbjct: 349 AGPS 352
Score = 29.3 bits (64), Expect = 10.0
Identities = 28/101 (27%), Positives = 31/101 (30%), Gaps = 15/101 (14%)
Query: 191 DLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPE 250
D S GP P P P +P + GT P P P P P+
Sbjct: 1415 DTSTPDGPPLAPAAAVPG------PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468
Query: 251 LSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPP 291
PPP P PPPL S P PPP
Sbjct: 1469 PQ------PPPPPPPPQPALPSPPPLV---APTPSSPPPPP 1500
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 57.4 bits (137), Expect = 3e-08
Identities = 46/172 (26%), Positives = 66/172 (38%), Gaps = 23/172 (13%)
Query: 1 MAAVAAEAAATAASPGEGGAGEAEPEM--------EPIPGSEAGTDPLPVTATEASVPDG 52
+ +VA A ++A S E + E P + P G++ P P E P G
Sbjct: 5 LLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQG 64
Query: 53 ETDGQQSAPQADEPPLPPP---------PPPPGELARSPEAVGPELEAEEKLSVRVAESA 103
Q P+ +P PPP PP PG+ P G + + R +
Sbjct: 65 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP---RPGKPE 121
Query: 104 AAAPQGGPEL---PPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDST 152
PQGG + PP P P PP + + P P+P P PP GG+ +
Sbjct: 122 GPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 173
Score = 53.5 bits (127), Expect = 5e-07
Identities = 40/142 (28%), Positives = 53/142 (37%), Gaps = 16/142 (11%)
Query: 24 EPEMEPIPGSEAGTDPLPVTAT-EASVPDGETDGQQSAPQADEPPLPPP---------PP 73
+PE P G P P E P G Q P+ +P PPP PP
Sbjct: 77 KPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 136
Query: 74 PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPEL---PPSPASPPEQPPAPEER 130
PG+ P G + + R + PQGG + PP P P PP +
Sbjct: 137 RPGKPEGPPPQGGNQSQGPPP---RPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQ 193
Query: 131 EEPPLPQPVAPALVPPAGGDST 152
+ P P+P P PP GG+ +
Sbjct: 194 SQGPPPRPGKPEGPPPQGGNQS 215
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/140 (27%), Positives = 51/140 (36%), Gaps = 16/140 (11%)
Query: 24 EPEMEPIPGSEAGTDPLPVTAT-EASVPDGETDGQQSAPQADEPPLPPP---------PP 73
+PE +P G P P E P G Q P+ +P PPP PP
Sbjct: 98 KPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 157
Query: 74 PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPEL---PPSPASPPEQPPAPEER 130
PG+ P G + + + PQGG + PP P P PP +
Sbjct: 158 RPGKPEGPPPQGGNQSQGPPP---HPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214
Query: 131 EEPPLPQPVAPALVPPAGGD 150
+ P P+P P P GG+
Sbjct: 215 SQGPPPRPGKPEGPPSQGGN 234
Score = 47.8 bits (112), Expect = 3e-05
Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 36/160 (22%)
Query: 24 EPEMEPIPGSEAGTDPLPVTAT-EASVPDGETDGQQSAPQADEPPLPPP---------PP 73
+PE P G P P E P G Q P+ +P PPP PP
Sbjct: 119 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 178
Query: 74 PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG------------PELPPS----- 116
PG+ P G + + R + PQGG PE PPS
Sbjct: 179 HPGKPEGPPPQGGNQSQGPPP---RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNK 235
Query: 117 PASPPEQP-----PAPEEREEPPLPQPVA-PALVPPAGGD 150
P PP P P P+E +P P P P PP GG+
Sbjct: 236 PQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGN 275
Score = 46.2 bits (108), Expect = 8e-05
Identities = 38/135 (28%), Positives = 48/135 (35%), Gaps = 16/135 (11%)
Query: 24 EPEMEPIPGSEAGTDPLPVTAT-EASVPDGETDGQQSAPQADEPPLPPP---------PP 73
+PE P G P P E P G Q P+ +P PPP PP
Sbjct: 161 KPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 220
Query: 74 PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG--PELPPSPASPPEQPPAPEERE 131
PG+ P G + + + PQ G P+ PP P P+ PP P
Sbjct: 221 RPGKPEGPPSQGGNKPQGPPP---HPGKPQGPPPQEGNKPQRPPPPGR-PQGPPPPGGNP 276
Query: 132 EPPLPQPVAPALVPP 146
+ PLP P PP
Sbjct: 277 QQPLPPPAGKPQGPP 291
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/138 (28%), Positives = 50/138 (36%), Gaps = 27/138 (19%)
Query: 24 EPEMEPIPGSEAGTDPLPVTAT-EASVPDGETDGQQSAPQADEPPLPP---------PPP 73
+PE P G P P E P G Q P+ +P PP PPP
Sbjct: 182 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPP 241
Query: 74 PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQ---PPAPEER 130
PG+ P G + + P G P+ PP P P+Q PPA + +
Sbjct: 242 HPGKPQGPPPQEGNKPQRPP-------------PPGRPQGPPPPGGNPQQPLPPPAGKPQ 288
Query: 131 EEPPLPQPVAPALVPPAG 148
PP PQ P PP G
Sbjct: 289 GPPPPPQGGRPHR-PPQG 305
Score = 36.6 bits (83), Expect = 0.063
Identities = 25/83 (30%), Positives = 30/83 (36%), Gaps = 11/83 (13%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDG---------QQSAPQADE 65
P +GG P P PG G P + P G G Q P A +
Sbjct: 229 PSQGGNKPQGPP--PHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGK 286
Query: 66 PPLPPPPPPPGELARSPEAVGPE 88
P PPPPP G R P+ P+
Sbjct: 287 PQGPPPPPQGGRPHRPPQGQPPQ 309
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 57.0 bits (136), Expect = 4e-08
Identities = 46/150 (30%), Positives = 57/150 (38%), Gaps = 28/150 (18%)
Query: 31 PGSEAGTDPLPVTATEASVPDGETDGQQS-------APQADEPP-LPPPPPPPGELARSP 82
PG + LPV S D T G + AP A+ P PPPPPP SP
Sbjct: 495 PGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSP 554
Query: 83 EAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSP-----ASPPEQPPAPEEREEPPLPQ 137
+ P A A G PE PP+P PP PP P + P+P
Sbjct: 555 QEAPPS-----------APPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPP 603
Query: 138 PVAPALVPPAGGDSTV----SQLIPGSEVR 163
P P PP G + S+L PG + +
Sbjct: 604 PPPPPPPPPGGPPDALGRRDSELGPGVKAK 633
Score = 43.5 bits (101), Expect = 5e-04
Identities = 35/134 (26%), Positives = 45/134 (33%), Gaps = 37/134 (27%)
Query: 3 AVAAEAAATAASPG--------------EGGAGEAEPEMEPIPGSEAGTDPLPVTATEAS 48
AVA + A +PG E G A P P+PG + + P +A
Sbjct: 507 AVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP 566
Query: 49 VPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQ 108
G + + P + P PPPPPPP P GP P
Sbjct: 567 PLPGSPEPPPAPPLPGDLPPPPPPPPP-----PPGTDGP------------------VPP 603
Query: 109 GGPELPPSPASPPE 122
P PP P PP+
Sbjct: 604 PPPPPPPPPGGPPD 617
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/109 (29%), Positives = 42/109 (38%), Gaps = 13/109 (11%)
Query: 3 AVAAEAAATAASPG----------EGGAGEAEPEMEPIPGSEAG--TDPLPVTATEASVP 50
A AAE A AA P + A P+ P+PGS PLP P
Sbjct: 531 APAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPP 590
Query: 51 DGETDGQQS-APQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVR 98
G P PP PPP PP L R +GP ++A++ + +
Sbjct: 591 PPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTK 639
Score = 29.3 bits (64), Expect = 10.0
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 5/35 (14%)
Query: 109 GGPELPPSPASPPEQPPAPEEREEPPLPQPVAPAL 143
G E P PA+PP + PAP P P P A L
Sbjct: 6 GSAEQPAGPAAPPPKQPAP-----PKQPMPAAGEL 35
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 56.6 bits (135), Expect = 6e-08
Identities = 49/151 (32%), Positives = 65/151 (43%), Gaps = 36/151 (23%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP--- 71
P +GG +P+ P PG G P + P G+ G PQ +P PPP
Sbjct: 61 PPQGGN---KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP--PQGGKPQGPPPQGG 115
Query: 72 -----PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP-----SPASPP 121
PPPPG+ P+ GP + K +A +P G P+ PP +P PP
Sbjct: 116 NKPQGPPPPGK----PQ--GPPAQGGSK------SQSARSPPGKPQGPPQQEGNNPQGPP 163
Query: 122 EQPPA---PEEREEPPLPQPVAPALVPPAGG 149
PPA P++ + PP QP P PP GG
Sbjct: 164 --PPAGGNPQQPQAPPAGQPQGPPR-PPQGG 191
Score = 47.4 bits (111), Expect = 4e-05
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 35/159 (22%)
Query: 1 MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSA 60
+ +VA A ++A + E + E P + I G+ G P G Q
Sbjct: 5 LLSVALLALSSAQNLNEDVSQEESPSL--IAGNPQGPSP-----------QGGNKPQGPP 51
Query: 61 PQADEPPLPPP--------PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPE 112
P +P PPP PPPPG+ P+ GP + ++ S R +P G P+
Sbjct: 52 PPPGKPQGPPPQGGNKPQGPPPPGK----PQ--GPPPQGDKSRSPR-------SPPGKPQ 98
Query: 113 LPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDS 151
PP P+ PP P+ +P P P PPA G S
Sbjct: 99 GPPPQGGKPQGPP-PQGGNKPQGPPPPGKPQGPPAQGGS 136
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/103 (28%), Positives = 37/103 (35%), Gaps = 14/103 (13%)
Query: 57 QQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPS 116
Q +PQ P PPPPP + GP + K P G P+ PP
Sbjct: 37 QGPSPQGGNKPQGPPPPPG-------KPQGPPPQGGNK-------PQGPPPPGKPQGPPP 82
Query: 117 PASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPG 159
P +P + + P PQ P PP GG+ PG
Sbjct: 83 QGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPG 125
Score = 31.2 bits (69), Expect = 2.6
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 15 PGEGGA----GEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP 70
P +GG+ + P P + G +P P G Q AP A +P PP
Sbjct: 131 PAQGGSKSQSARSPPGKPQGPPQQEGNNP-----QGPPPPAGGNPQQPQAPPAGQPQGPP 185
Query: 71 PPPPPGELARSPE 83
PP G +R P+
Sbjct: 186 RPPQGGRPSRPPQ 198
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 56.2 bits (134), Expect = 8e-08
Identities = 48/153 (31%), Positives = 59/153 (38%), Gaps = 30/153 (19%)
Query: 9 AATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPL 68
AAT SP G A P ++ P A T P P P G A PP
Sbjct: 1061 AATLPSPK---GGPATPSLKGAPTPPAATPPSPKGGPATPSPKG----------APMPPA 1107
Query: 69 PPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP---SPASPPEQPP 125
PP P G LA P P A + +P+GG PP +P +P PP
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPA----------ATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 126 APEE--REEPPLPQPVAPALVPPA--GGDSTVS 154
+P+ PP P PA PP+ GG +T S
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Score = 56.2 bits (134), Expect = 8e-08
Identities = 47/161 (29%), Positives = 64/161 (39%), Gaps = 13/161 (8%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADE--PPLP 69
AA+P G A P + P + A T P P P G + P + + P P
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 70 PP---PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP---SPASPPEQ 123
PP P PP A P G K + A +P+GGP P +P P
Sbjct: 1259 PPKGAPTPPA--ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 124 PPAPEEREEPPLPQ--PVAPALVPPA-GGDSTVSQLIPGSE 161
PP+P+ P P+ P PA+ PP+ G T+ P S+
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Score = 52.8 bits (125), Expect = 8e-07
Identities = 50/166 (30%), Positives = 65/166 (39%), Gaps = 33/166 (19%)
Query: 9 AATAASPGEGGAGEAEPEMEPIPGSEAGTDPLP-----------VTATEASVPDGETDGQ 57
AAT SP +GG P+ P+P A T P P T A+ P G
Sbjct: 1084 AATPPSP-KGGPATPSPKGAPMP--PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 58 QSAPQADEP--PLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG---PE 112
+ P P P PP P G LA P P A + +P+GG P
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA----------ATPPSPKGGLATPS 1190
Query: 113 LPPSPASPPEQPPAPEEREEPPLPQ--PVAPALVPPA--GGDSTVS 154
+P +P PP+P+ P P+ P PA PP+ GG +T S
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/151 (27%), Positives = 59/151 (39%), Gaps = 10/151 (6%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
AA+P G A P + P + A T P P P G + P + + L P
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166
Query: 72 PP---PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG---PELPPSPASPPEQPP 125
PP P A P G K + + +P+GG P +P +P PP
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226
Query: 126 APEEREEPPLPQ--PVAPALVPPA--GGDST 152
+P+ P P+ P PA PP+ GG +T
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Score = 50.4 bits (119), Expect = 4e-06
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 27/149 (18%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEAS-VPDGETDGQQSAPQADEPPLPP 70
AA+P G A P + P A T P P + A+ P G A PP
Sbjct: 990 AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG----------ASTPPAAT 1039
Query: 71 PPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP---SPASPPEQPPAP 127
PP P G A +P G + + +P+GGP P +P P PP+P
Sbjct: 1040 PPSPKGSPAATPLPKG---------APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Query: 128 EEREEPPLPQ--PVAPALVPPA--GGDST 152
+ P P+ P+ PA PP+ GG +T
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Score = 48.9 bits (115), Expect = 1e-05
Identities = 89/369 (24%), Positives = 116/369 (31%), Gaps = 112/369 (30%)
Query: 9 AATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPL 68
AAT SP +G G P+ P P + P A+ P + G + P + E P
Sbjct: 1314 AATPPSP-KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK--GGPTTPSSKEGPT 1370
Query: 69 P--------------PPPPPPGELARSPEAVGPELEAEEKLSVRVAES------------ 102
P PP P G SP+ P A LS + A +
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKG-DPTSPAVIPLSPKKAPATPVTREGAATPS 1429
Query: 103 ------------------AAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPV----- 139
A +AP+GGP P S P P +EPP P+ V
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
Query: 140 ---APALVPPAGGDSTVSQLIPGS--EVRVT----LDHIIEDALVVSFRFGEKLFSGVLM 190
APA P G T+ +IP S EV T D I A ++S +
Sbjct: 1490 PKKAPATPAPMGA-PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK----------- 1537
Query: 191 DLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPE 250
P T+ PK +P T P P+P P
Sbjct: 1538 ----------TPATLAPKEALIPPAMTVPSPKKT---------------PAIPTPKEAP- 1571
Query: 251 LSLAESLWTSKPP---PLFHEGAPYPPPLFIRDTYNQSIPQ--------PPPRKIKRPKR 299
+ S S PP P ++GAP P L I P+ PP K P
Sbjct: 1572 -ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 300 KMYREEPTS 308
+ PTS
Sbjct: 1631 PAPKGTPTS 1639
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/151 (27%), Positives = 57/151 (37%), Gaps = 10/151 (6%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
AA+P G A P + P + A T P P P G + P + + L P
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
Query: 72 PP---PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG---PELPPSPASPPEQPP 125
P P A P G K + + +P+GG P +P +P PP
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 126 APE--EREEPPLPQPVAPALVPPA--GGDST 152
+P+ PP P PA PP+ GG +T
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 35/168 (20%)
Query: 9 AATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPL 68
AAT SP +GG P+ P P A T P P P G A PP
Sbjct: 944 AATPPSP-KGGPATPSPKWAPTP--PAATPPSPKGGPATPSPKG----------APTPPA 990
Query: 69 PPPPPPPG-------ELARSPEAVGPELEAEEKLSVRVAESAAA-------APQGGPELP 114
PP P G + A +P AV P + + A+ +P+G P
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050
Query: 115 PSPASPPEQPPA--PEEREEPPLPQ----PVAPALVPPA--GGDSTVS 154
P P P P A P + P P P PA PP+ GG +T S
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098
Score = 43.9 bits (102), Expect = 4e-04
Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 8/137 (5%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPP--PPGELARSPEAVG 86
P P E P P A S+ ++ P P P P P A P G
Sbjct: 894 PFP-KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 87 PELEAEEKLSVRVAESAAAAPQGGPELPP---SPASPPEQPPAPEEREEPPLPQ--PVAP 141
K + + +P+GGP P +P P PP+P+ P P+ P P
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
Query: 142 ALVPPAGGDSTVSQLIP 158
A+ PP+ S + P
Sbjct: 1013 AVTPPSPKGSPAATPFP 1029
Score = 43.1 bits (100), Expect = 7e-04
Identities = 46/159 (28%), Positives = 56/159 (35%), Gaps = 27/159 (16%)
Query: 2 AAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTD-----PLPVTATEASVPDG-ETD 55
AA A+P GA P P T P P AT S+ G T
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 56 GQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP 115
+ AP P + PP P G A SP P A + +P+G P PP
Sbjct: 1282 PHKGAP---NPAVVTPPSPKGGPATSPPKGAPTPPA----------ATPPSPKGSPGTPP 1328
Query: 116 SPASPPEQPPAPEEREEPPLPQ--PVAPALVPPAGGDST 152
+P PPA PP P+ P PA P + G T
Sbjct: 1329 PKGAP--TPPA----VTPPSPKGTPTLPATTPSSKGGPT 1361
Score = 40.8 bits (94), Expect = 0.003
Identities = 41/159 (25%), Positives = 50/159 (31%), Gaps = 29/159 (18%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDG----------ETDGQQSAP 61
AA+P G A P + P T P P S P G G P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 62 QADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPP 121
P PP PP SP+ P L A + +GGP P S P
Sbjct: 1328 PPKGAPTPPAVTPP-----SPKGT-PTLPA-----------TTPSSKGGPTTPSSKEGPT 1370
Query: 122 EQPPAPEEREEPPL--PQPVAPALVPPAGGDSTVSQLIP 158
P + P + P P +P GD T +IP
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409
Score = 39.7 bits (91), Expect = 0.007
Identities = 41/133 (30%), Positives = 52/133 (39%), Gaps = 14/133 (10%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPE 88
P P S G P P T S P G T + P LP P P A +A
Sbjct: 856 PTPPSPKGA-PTPSAVTPLS-PKGVTLPPKETPTPSVVNLPFPKEGPATPAPK-QAPALS 912
Query: 89 LEAEEKLSVRVAESAAAAPQGGPELPP---SPASPPEQPPAPEEREEPPLPQ--PVAPAL 143
+ + R A AP+G P P +P P PP+P+ P P+ P PA
Sbjct: 913 MTSSSPKKAR----ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 144 VPPA--GGDSTVS 154
PP+ GG +T S
Sbjct: 969 TPPSPKGGPATPS 981
Score = 39.3 bits (90), Expect = 0.010
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 5/118 (4%)
Query: 39 PLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVR 98
P + EA +P T A P P P + A SP AV P + K +
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP---STYKGAPS 1595
Query: 99 VAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQ--PVAPALVPPAGGDSTVS 154
E P +P P PP+PE+ P P+ P +P + P + DS S
Sbjct: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653
Score = 35.8 bits (81), Expect = 0.11
Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 10/106 (9%)
Query: 75 PGELARSPEAVGPEL-EAEEKLSVRVAESA----AAAPQGGPELPPSPASPPEQPPAPEE 129
PGE + A EL + + + +V SA AA Q GP LPP + P+Q P
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 130 REEPPLPQPVAPALVP-----PAGGDSTVSQLIPGSEVRVTLDHII 170
+ P P P A P P T L E L ++I
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLI 107
Score = 35.8 bits (81), Expect = 0.11
Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 13/150 (8%)
Query: 9 AATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPL 68
A T P + P + P P ++ G+ T A + + D ++A D
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 69 PPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPAS--PPEQ--- 123
P P P E S E + SAA +P L PSP PP+Q
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817
Query: 124 PPAPEEREEPPLPQPVAPA-------LVPP 146
P +P E P +P+APA L+PP
Sbjct: 1818 PSSPGLVLESP-SKPLAPADEDELLPLIPP 1846
Score = 33.5 bits (75), Expect = 0.53
Identities = 31/119 (26%), Positives = 41/119 (34%), Gaps = 9/119 (7%)
Query: 41 PVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVA 100
P T P + + S+P A P P P EL P P S + A
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP--------SPKEA 1613
Query: 101 ESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPG 159
+ A PE P+ +P P +P P +PA V G +TV Q G
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG-ATVPQASKG 1671
Score = 31.6 bits (70), Expect = 2.0
Identities = 35/145 (24%), Positives = 52/145 (35%), Gaps = 3/145 (2%)
Query: 5 AAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQAD 64
A + AT++SP + A A P P + + P V AT +S D +
Sbjct: 1480 APKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538
Query: 65 EPPLPPPPP--PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPE 122
L P PP SP+ +E + ++ A++ P P SP E
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 123 QPPAPEEREEPPLPQPVAPALVPPA 147
P P P PA+ PP+
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPS 1623
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 55.8 bits (133), Expect = 1e-07
Identities = 76/272 (27%), Positives = 95/272 (34%), Gaps = 60/272 (22%)
Query: 60 APQADEPPLPPPPPPPGELARSPEAVGPELEAEEK-LSVRVAESAAAAPQGGPELPPSPA 118
+PQ +EP L P P P L+ PE ++EE LS R ES + P L P P
Sbjct: 807 SPQTEEPHLSPVPEEPC-LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
Query: 119 SPPEQP---PAPEERE---------------EPPLPQPVAPALVP--------PAGGDST 152
PPE+P PAPEE EP L +P P L P P+G S
Sbjct: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL 925
Query: 153 VSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKREYK 212
QL+P + L II A + L +L FG G
Sbjct: 926 SPQLMPPDPLPPPLSPIITAAAPPAL--------SPLGELEYPFGAKG--------DSDP 969
Query: 213 DKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPELSLAESLWTSKPPPLFHEGAPY 272
+ P A P+ E C DP PVP L + P+ E P
Sbjct: 970 ESPLAAPILETPISPPPEANC-------TDPEPVPPMILPPSPGSPVGPASPILME--PL 1020
Query: 273 PP---PLFIRDTYNQSIP----QPPPRKIKRP 297
PP PL Q+ P PP + P
Sbjct: 1021 PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052
Score = 50.1 bits (118), Expect = 5e-06
Identities = 48/160 (30%), Positives = 64/160 (40%), Gaps = 28/160 (17%)
Query: 9 AATAASPGEGGAGEAEPEMEPI--PGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEP 66
A+ + P E PE P+ P + PLPV + + P+ + S P + P
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE---ESPLSPPPEESP 679
Query: 67 PLPPPP-----PPPGELARSPE------AVGPE-----LEAEEKLSVRVAESAAAAPQG- 109
PPP PPP + SP + PE L EE + + E P+
Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE 739
Query: 110 GPELPPSPASP-----PEQPPAPEEREEPPL-PQPVAPAL 143
GP L P P P PE+P + EEP L PQP P L
Sbjct: 740 GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL 779
Score = 49.3 bits (116), Expect = 9e-06
Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 12/99 (12%)
Query: 60 APQADEPPLPPPP------PPPGELARSP--EAVGPELEAEEK-LSVRVAESAAAAPQGG 110
+P +E P PPP PPP EL SP EA+ EE LS ES + P
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 111 PELPP---SPASPPEQPPAPEEREEPPLPQPVAPALVPP 146
P SP SPPE+ P E P P P A L PP
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP 548
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/139 (28%), Positives = 50/139 (35%), Gaps = 16/139 (11%)
Query: 15 PGEGGAGEAEPEMEPI--PGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPP 72
P E PE P+ P E+ P P EAS + +P +E PL PPP
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPP----EASRLFPPFEESPLSPPPEESPLSPPP 621
Query: 73 ------PPPGELARSP----EAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPE 122
PPP + SP + P E + V + P+ P PP SP
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681
Query: 123 QPPAPEEREEPPLPQPVAP 141
PP PP P +P
Sbjct: 682 PPPEASRLSPPPEDSPTSP 700
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 11/128 (8%)
Query: 24 EPEMEPIPGSEAGTDP--LPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARS 81
EP + P+ G A ++P P++ +P + +PQ P PPP P A +
Sbjct: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947
Query: 82 PEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAP 141
P A+ P E E + +S +P P L +P SPP + + P+PV P
Sbjct: 948 PPALSPLGELEYPFGAK-GDSDPESPLAAPIL-ETPISPPPEANCTD-------PEPVPP 998
Query: 142 ALVPPAGG 149
++PP+ G
Sbjct: 999 MILPPSPG 1006
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/172 (28%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 9 AATAASPGEGGAGEAEPEMEPI-PGSEAGTDPLPVTATEASVPDGET------DGQQSAP 61
A+ + P E PE P+ P EA P + S P E+ + + +P
Sbjct: 569 ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628
Query: 62 QADEPPLPPPPP-----PPGELAR-SPEAVGPELEA---EEKLSVRVAESAAAAPQGGPE 112
++ P+ PPP PP E++R SP V L E LS ES + P
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Query: 113 LPPSPASPPEQP--------PAPEE-------REEPPLPQPVAPALVPPAGG 149
L P P P P P PE+ E P LP P P L P + G
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/161 (30%), Positives = 58/161 (36%), Gaps = 41/161 (25%)
Query: 25 PEMEPI--PGSEAGTDPLPVTATEASVPDGETDGQQSAPQA-------DEPPLPPPP--- 72
PE P+ P E+ T P P A+ S P E P+A +E PL PPP
Sbjct: 444 PEESPLSPPPEESPTSP-PPEASRLSPPPEELPASP-LPEALHLSRPLEESPLSPPPEES 501
Query: 73 ---PPPGELARSPEAVGPELEAEEKLSVRVAESAAAAP-QGGPELPP---SPASPP---- 121
PPP SP P EE E+ + P + P PP SP SPP
Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561
Query: 122 ----------------EQPPAPEEREEPPLPQPVAPALVPP 146
E P +P E P P P A L PP
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/166 (29%), Positives = 63/166 (37%), Gaps = 31/166 (18%)
Query: 8 AAATAASPGEGGAGEAEP-EMEPI--PGSEAGTDPLPVTATEASVPDGETDGQQSAPQAD 64
A T SP + + P E P+ P E T P P A+ S P E+ +P +
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP-PPEASRLSPPPEESP---MSPPPE 586
Query: 65 EPPLPPPP---------------PPPGELARSPEAVGPELEA---EEKLSVRVAESAAAA 106
E P+ PPP PPP E SP L + +S ES +
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646
Query: 107 PQGGPELPPSP-----ASPPEQPP-APEEREEPPLPQPVAPALVPP 146
P L P P + PPE+ P +P E P P P A L PP
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/225 (25%), Positives = 82/225 (36%), Gaps = 25/225 (11%)
Query: 31 PGSEAGTDPLPVTATEASVPD-GETDGQQSAPQ----ADEPPLPPP--PPPPGELARSPE 83
P E GT P+ P G G Q+ P A P PP P PPG L+ P
Sbjct: 4242 PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP- 4300
Query: 84 AVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPAL 143
+GP S + + + P +LP PP P P+ + P L P P
Sbjct: 4301 VLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP-QGPTLEPP--PGR 4357
Query: 144 VPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPV 203
V PA + G D++ E L G L ++ + P +
Sbjct: 4358 VSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ----SSLVPGHLDQVNGQVVPEASQL 4413
Query: 204 TVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPH 248
++ K+E +++P A+ QS VK EANG P H
Sbjct: 4414 SI--KQEPREEPCALGAQS--------VKREANGEPIGAPGTSNH 4448
Score = 40.0 bits (92), Expect = 0.006
Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 17/133 (12%)
Query: 31 PGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELE 90
P E+ P P ++ + + + + +P + P PPP P P
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP 556
Query: 91 AEEKLSVR---VAESAAAAPQGGPELPP---SPASPP-----------EQPPAPEEREEP 133
E+L A + P+ P PP SP SPP E P +P E P
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP 616
Query: 134 PLPQPVAPALVPP 146
P P A L PP
Sbjct: 617 LSPPPEASRLSPP 629
Score = 38.5 bits (88), Expect = 0.016
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 17/145 (11%)
Query: 10 ATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP 69
A+ P G G P+ EP P P S PD G + P A P P
Sbjct: 2335 ASQVEPQSPGLG-LRPQ-EPPPAQALAPSP-------PSHPDIFRPGSYTDPYAQPPLTP 2385
Query: 70 PPPPPPGE--LARSPEAVGPELEAEEKLSVRVAESAAA----APQGGPELPPSPASPPEQ 123
P PPP E A P ++ + + S + S+ + P PSP +P Q
Sbjct: 2386 RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445
Query: 124 PPAPEER--EEPPLPQPVAPALVPP 146
P P R P P AP PP
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAPLHKPP 2470
Score = 37.7 bits (86), Expect = 0.028
Identities = 49/203 (24%), Positives = 74/203 (36%), Gaps = 16/203 (7%)
Query: 65 EPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQP 124
+PP+P P PP S GP L + + VA + P G P L PS S E
Sbjct: 2548 KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVA-TGNFHPSGSP-LGPSSGSTGESY 2605
Query: 125 PAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKL 184
R P+++PP D ++ L G+ R + +E G L
Sbjct: 2606 GLSPLR---------PPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSL 2656
Query: 185 FSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAM----PLQSNTFQEGTEVKCEANGAVP 240
+ L ++ G G+ T K+ + + + +Q NT ++ E A GAV
Sbjct: 2657 ATAELPG-TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVG 2715
Query: 241 DDPSPVPHPELSLAESLWTSKPP 263
S P E L + P
Sbjct: 2716 PPGSWGAEPSSPAFEQLSRGQTP 2738
Score = 37.0 bits (84), Expect = 0.048
Identities = 46/166 (27%), Positives = 61/166 (36%), Gaps = 22/166 (13%)
Query: 10 ATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATE--ASVPD------GETDGQQSAP 61
A SPG GG +EP + P P E+ L V E AS P G D S
Sbjct: 2256 AVPESPGVGGGKASEPLLSPPPFGES-RKALEVKKEELGASSPSYGPPNLGFVDSPSSGT 2314
Query: 62 QADEPPLPPP-----PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPEL--P 114
L P P P P++ G L +E A++ A +P P++ P
Sbjct: 2315 HLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP---PPAQALAPSPPSHPDIFRP 2371
Query: 115 PSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGS 160
S P QPP + PP P + +PP S +P S
Sbjct: 2372 GSYTDPYAQPPLTPRPQPPP---PESCCALPPRSLPSDPFSRVPAS 2414
Score = 37.0 bits (84), Expect = 0.048
Identities = 65/285 (22%), Positives = 88/285 (30%), Gaps = 88/285 (30%)
Query: 8 AAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVP-------DGETDGQQSA 60
AAA A + G G+ AEP G P T ++S+ G G S
Sbjct: 2707 AAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSF 2766
Query: 61 PQADEPPLPPPP------------------------PPPGE--LARSPEAVGPELEAEEK 94
P D PPPP P PG L + + + + +A
Sbjct: 2767 PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826
Query: 95 LSVRVAESAAAAPQGGPELPPSPASPP-----EQPPAPEEREEPPLPQPVAPALVPPAGG 149
S+R A SA GPEL P + P P E P+P P PA
Sbjct: 2827 TSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGE----PVPGPAGPAQF----- 2877
Query: 150 DSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKR 209
+ L H ++ K GP G P FP +
Sbjct: 2878 --------------IELRH----------------------NVQKGLGPGGTP---FPGQ 2898
Query: 210 EYKDKPEAMPLQSNTFQEGTE--VKCEANGAVPDDPSPVPHPELS 252
+P P+ + + E +G P PS P PEL+
Sbjct: 2899 GPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELN 2943
Score = 34.7 bits (78), Expect = 0.24
Identities = 48/168 (28%), Positives = 64/168 (38%), Gaps = 37/168 (22%)
Query: 15 PGEGGAGEAEPE----MEPIPGSEAGT------DPLPVTAT---EASVPDGETDGQQSAP 61
P E + EP + P PGS G +PLP + + S+ + Q +P
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP 1044
Query: 62 QADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPP 121
A +P P P G++ V E E E + +V+E P L PS SP
Sbjct: 1045 PALPLSVPSPLSPIGKVV----GVSDEAELHEMETEKVSEPEC------PALEPSATSP- 1093
Query: 122 EQPPAPEEREEPPLPQPVAPAL----------VPPAGGDSTVSQLIPG 159
P+P P P P APAL P G D+ SQ PG
Sbjct: 1094 --LPSPMGDLSCPAPSP-APALDDFSGLGEDTAPLDGIDAPGSQPEPG 1138
Score = 33.9 bits (76), Expect = 0.41
Identities = 33/135 (24%), Positives = 46/135 (34%), Gaps = 12/135 (8%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP--PPPPPPGEL-ARSPEAV 85
P PG+ P P SA +PP P P PGEL + P V
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
Query: 86 GPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPALVP 145
++ +++ + A P P P +PP PP P P P + + P
Sbjct: 2168 PAQVPSQDPFGLAPAY---------PLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP 2218
Query: 146 PAGGDSTVSQLIPGS 160
AG PG+
Sbjct: 2219 GAGQPGEFHTTPPGT 2233
Score = 33.9 bits (76), Expect = 0.41
Identities = 75/312 (24%), Positives = 97/312 (31%), Gaps = 52/312 (16%)
Query: 11 TAASPGEGGAGEAEPEMEPIPGSEAGTD---PLPVTATEASVPDGETDGQQSA-PQADEP 66
T A G +P +PG ++ + LP A VP + G A P
Sbjct: 2131 TPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP-PQVPAQVPSQDPFGLAPAYPLEPRF 2189
Query: 67 PLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPA 126
P PP PP A P L A S A Q G P +P QP
Sbjct: 2190 PTAPPTYPPYPSPTGAPAQPPMLG---------ASSRPGAGQPGEFHTTPPGTPRHQPST 2240
Query: 127 PEEREEPPLP--QPVAPALVPPAGGDSTVSQLI---PGSEVRVTLDHIIEDALVVSFRFG 181
P+ +P P +A P GG L+ P E R L+ + ++ L S
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE-VKKEELGAS---- 2295
Query: 182 EKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPD 241
S +GP P + D P S T G E+K P
Sbjct: 2296 -----------SPSYGP--------PNLGFVDSP-----SSGTHLGGLELKTPDVFKAPL 2331
Query: 242 DPSPVPHPELSLAESLWTSKPPP--LFHEGAPYPPPLFIRDTYNQSIPQPP--PRKIKRP 297
P S L +PPP P P +F +Y QPP PR P
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 298 KRKMYREEPTSI 309
P S+
Sbjct: 2392 PESCCALPPRSL 2403
Score = 33.5 bits (75), Expect = 0.53
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 70 PPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAP-- 127
P P PP + + + ++ +LS E + P L PSPASPP +P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVR---QLSAPPPEEPSPPPS---PLAPSPASPPTEPLVELP 4937
Query: 128 -EEREEPPLPQPVAPALVP 145
E EPP+P P+ A P
Sbjct: 4938 TEPLAEPPVPSPLPLASSP 4956
Score = 33.1 bits (74), Expect = 0.69
Identities = 29/114 (25%), Positives = 40/114 (35%), Gaps = 11/114 (9%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEP-PLPPPPPPPGELARSPEAVGP 87
P PG +P + P G G ++ Q EP PL P G+ G
Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKG---GHVTSMQPKEPGPLQCEAKPLGK-------AGV 424
Query: 88 ELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAP 141
+LE + + + P+ P PP SP PP PP P +P
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP 478
Score = 32.3 bits (72), Expect = 1.2
Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 34/156 (21%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEASVP---------DGETDGQQSAPQADEPPLPPPPPPP 75
P +EP + T PLP + S P D G+ +AP D P P P
Sbjct: 1084 PALEP-----SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAP-LDGIDAPGSQPEP 1137
Query: 76 GELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPL 135
G+ S L +E K S + + AP E+ P Q EE+EEP
Sbjct: 1138 GQTPGS-------LASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRA 1190
Query: 136 P-QPVAPALVPP---------AGGDSTVSQLIPGSE 161
P P P L+ + GD++ S PGSE
Sbjct: 1191 PVAPTPPTLIKSDIVNEISNLSQGDASAS--FPGSE 1224
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/135 (34%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 7 EAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPL-PVTATEASVPDGET--DGQQSAPQA 63
EA A +P G AG P P G A T P P+ P DG+ P
Sbjct: 44 EAPAPMKTPEAGLAGRPSPWTTP--GRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDL 101
Query: 64 DEPPLPPPPPP---PGELARSPEAVGPELEAE-EKLSVRVAESAAAAPQGGPELPPSPAS 119
D P PPPPPP P E +P +G L A+ E+L + AP GP + P P
Sbjct: 102 DLLPPPPPPPPVLLPSE-EEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLR 160
Query: 120 PPEQ--PPAPEEREE 132
P E+ PP P E E
Sbjct: 161 PMEEELPPPPAEPVE 175
Score = 35.0 bits (79), Expect = 0.18
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 17/92 (18%)
Query: 226 QEGTEVKCEANGAVP-DDPSPVPHPELSLA--ESLWTSK----------PPPLFHEGAPY 272
+E + CEA P + P+P+ PE LA S WT+ P LF+ G P
Sbjct: 28 EEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPP 87
Query: 273 PPPLFIRDTYNQSI----PQPPPRKIKRPKRK 300
PPP+ + + P PPP + P +
Sbjct: 88 PPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEE 119
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/135 (34%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 7 EAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPL-PVTATEASVPDGET--DGQQSAPQA 63
EA A +P G AG P P G A T P P+ P DG+ P
Sbjct: 44 EAPAPMKTPEAGLAGRPSPWTTP--GRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDL 101
Query: 64 DEPPLPPPPPP---PGELARSPEAVGPELEAE-EKLSVRVAESAAAAPQGGPELPPSPAS 119
D P PPPPPP P E +P +G L A+ E+L + AP GP + P P
Sbjct: 102 DLLPPPPPPPPVLLPSE-EEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLR 160
Query: 120 PPEQ--PPAPEEREE 132
P E+ PP P E E
Sbjct: 161 PMEEELPPPPAEPVE 175
Score = 35.0 bits (79), Expect = 0.18
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 17/92 (18%)
Query: 226 QEGTEVKCEANGAVP-DDPSPVPHPELSLA--ESLWTSK----------PPPLFHEGAPY 272
+E + CEA P + P+P+ PE LA S WT+ P LF+ G P
Sbjct: 28 EEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPP 87
Query: 273 PPPLFIRDTYNQSI----PQPPPRKIKRPKRK 300
PPP+ + + P PPP + P +
Sbjct: 88 PPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEE 119
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/169 (26%), Positives = 66/169 (39%), Gaps = 23/169 (13%)
Query: 1 MAAVAAEAAATAASPGEGGAGEAEPEM--------EPIPGSEAGTDPLPVTATEASVPDG 52
+ +VA A ++A + E + E P + P G++ P P + P G
Sbjct: 5 LLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQG 64
Query: 53 ETDGQQSAPQADEPPLPPP--------PPPPGELARSPEAVGPELEAEEKLSVRVAESAA 104
Q P +P PPP PPPPG+ P+ P+ + +
Sbjct: 65 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK----PQGPPPQGDKSRSPRSPPGKPQG 120
Query: 105 AAPQGG--PELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDS 151
PQGG P+ PP P P+ PP P+ +P P P PP GD+
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDN 168
Score = 53.1 bits (126), Expect = 6e-07
Identities = 49/161 (30%), Positives = 64/161 (39%), Gaps = 20/161 (12%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEAS-VPDGETDGQ--QSAPQADEPPLPP- 70
P +GG +P+ P PG G P + +S P G+ G Q Q PP PP
Sbjct: 143 PPQGGN---KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 199
Query: 71 ----PPPPPGELARSP----EAVGPELEAEEKL-SVRV--AESAAAAPQGG--PELPPSP 117
PPP G + P + GP + + K S R + PQGG P+ PP P
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 118 ASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
P+ PP + P P P PP GG + S P
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/164 (27%), Positives = 58/164 (35%), Gaps = 26/164 (15%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPL----------PVTATEASVPDGETDGQQSAPQAD 64
P +GG +P+ P PG G P P + P G Q P
Sbjct: 205 PPQGGN---KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG 261
Query: 65 EPPLPPP--------PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG--PELP 114
+P PPP PPPPG+ P G + + + PQGG P+ P
Sbjct: 262 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP---GKPQGPPPQGGNQPQGP 318
Query: 115 PSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
P P P+ PP + P P P PP GG + S P
Sbjct: 319 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362
Score = 52.8 bits (125), Expect = 8e-07
Identities = 50/151 (33%), Positives = 65/151 (43%), Gaps = 24/151 (15%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEAS-VPDGETDGQ--QSAPQADEPPLPP- 70
P +GG +P+ P PG G P + + +S P G+ G Q Q PP PP
Sbjct: 267 PPQGGN---KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 71 ----PPPPPGELARSP----EAVGPELEAEEKLSVRVAESAAAAPQGGPELPPS-PASPP 121
PPP G + P + GP + K R A S PQG P+ + P PP
Sbjct: 324 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS--RSARSPPGKPQGPPQQEGNNPQGPP 381
Query: 122 EQPPA---PEEREEPPLPQPVAPALVPPAGG 149
PPA P++ + PP QP P PP GG
Sbjct: 382 --PPAGGNPQQPQAPPAGQPQGPPR-PPQGG 409
Score = 49.7 bits (117), Expect = 7e-06
Identities = 41/149 (27%), Positives = 58/149 (38%), Gaps = 18/149 (12%)
Query: 24 EPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP---------PPP 74
+P+ P G P P + P G+ Q + +P PPP PPP
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 75 PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQP--PAPEEREE 132
PG+ P+ P+ + + + PQGG + S SPP +P P P+ +
Sbjct: 260 PGK----PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK-SRSSRSPPGKPQGPPPQGGNQ 314
Query: 133 P--PLPQPVAPALVPPAGGDSTVSQLIPG 159
P P P P P PP GG+ PG
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343
Score = 49.3 bits (116), Expect = 9e-06
Identities = 46/157 (29%), Positives = 58/157 (36%), Gaps = 31/157 (19%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPP 74
P +GG +P+ P PG G P + P G+ G PQ P PPPPP
Sbjct: 82 PPQGGN---KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP--PQGGNQPQGPPPPP 136
Query: 75 PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP--------SPASPPEQP-- 124
+ GP + K P G P+ PP S SPP +P
Sbjct: 137 G-------KPQGPPPQGGNK-------PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182
Query: 125 PAPEEREEP--PLPQPVAPALVPPAGGDSTVSQLIPG 159
P P+ +P P P P P PP GG+ PG
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 34/157 (21%)
Query: 24 EPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP---------PPP 74
+P+ P G P P + P G+ + S +P PPP PPP
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 197
Query: 75 PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP--------SPASPPEQP-- 124
PG+ P G + + P G P+ PP S SPP +P
Sbjct: 198 PGKPQGPPPQGGNKPQGPP-------------PPGKPQGPPPQGDNKSQSARSPPGKPQG 244
Query: 125 PAPEEREEP--PLPQPVAPALVPPAGGDSTVSQLIPG 159
P P+ +P P P P P PP GG+ PG
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 81 SPEAVGPELEAEEKLSVRVAESAAAAPQGG--PELPPSPASPPEQPPAPEEREEP--PLP 136
S + + ++ EE S+ A PQGG P+ PPSP P+ PP P+ +P P P
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPP-PQGGNQPQGPPP 73
Query: 137 QPVAPALVPPAGGDSTVSQLIPG 159
P P PP GG+ PG
Sbjct: 74 PPGKPQGPPPQGGNKPQGPPPPG 96
Score = 37.7 bits (86), Expect = 0.028
Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 28/104 (26%)
Query: 57 QQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGG--PELP 114
Q + PQ P PP PP + GP PQGG P+ P
Sbjct: 37 QGAPPQGGNKPQGPPSPPG-------KPQGPP------------------PQGGNQPQGP 71
Query: 115 PSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
P P P+ PP P+ +P P P PP GD + S P
Sbjct: 72 PPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 114
Score = 30.4 bits (67), Expect = 4.5
Identities = 14/34 (41%), Positives = 17/34 (50%)
Query: 50 PDGETDGQQSAPQADEPPLPPPPPPPGELARSPE 83
P G Q AP A +P PP PP G +R P+
Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/161 (29%), Positives = 63/161 (39%), Gaps = 24/161 (14%)
Query: 14 SPGEGGAGEAEPEMEPIPGSEAGTDPLPVT---------ATEASVPDGE-----TDGQQS 59
SP + A P ++ +P A T P T AT + +P T Q+
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPA-TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357
Query: 60 APQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP--SP 117
P PPL PP PP SP A P +A L+V + ++ + P P P P
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416
Query: 118 ASPPEQPPA------PEEREEPPLPQPVAPALVPPAGGDST 152
ASPP P A P PPL P +P PP +T
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/127 (29%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 25 PEMEPI--PGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSP 82
P P+ P S + P+ +AT S Q+ P PPL PP PP SP
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPS---------QAPPSLAAPPLQVPPSPPASPPMSP 454
Query: 83 EAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQ---PV 139
A P +A L+ + A PQ P L P PPA + P P P+
Sbjct: 455 SATPPP-QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 513
Query: 140 APALVPP 146
+P PP
Sbjct: 514 SPLATPP 520
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/140 (28%), Positives = 50/140 (35%), Gaps = 11/140 (7%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
A P + A P ++ P A P+ P+ A + P PP
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA------LAVHLLQAPFSPP 404
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPS--PASPPEQPP--AP 127
P PP + SP A P + + S AA P P PP+ P SP PP AP
Sbjct: 405 PSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 128 EEREEPPLPQPVAPALVPPA 147
PPL P PPA
Sbjct: 464 PPLAAPPLQLAKPPPQAPPA 483
Score = 43.1 bits (100), Expect = 7e-04
Identities = 46/181 (25%), Positives = 65/181 (35%), Gaps = 30/181 (16%)
Query: 8 AAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPP 67
A A + P G P P +A P++++ + P SAP + +
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 68 LPPPPPPPGELARSPEAVGPELEAEEKL--SVRVAESAAAAPQGGPEL-------PPSP- 117
PP PP + S + P L+A S ++ A PQ P L PPSP
Sbjct: 316 PSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 373
Query: 118 ASPPEQP---PAPEERE---------------EPPLPQPVAPALVPPAGGDSTVSQLIPG 159
ASPP P P+P+ PP+ P +P PP +T P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 160 S 160
S
Sbjct: 434 S 434
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/162 (28%), Positives = 59/162 (36%), Gaps = 41/162 (25%)
Query: 23 AEPEMEP--IPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPP--PPPGEL 78
A P + P P S+A P + A VP +P A PP PPP PP +L
Sbjct: 417 ASPPVSPSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 79 ARSPEAVGPELEA-------------------EEKLSVRVAESAAAAPQGGP-------E 112
A+ P P L S+ ++ A PQ P +
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 113 LPPS-PASP----PEQPPAP---EEREEPPLPQPVAPALVPP 146
+PPS PASP P +PP P P L +AP PP
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575
Score = 39.7 bits (91), Expect = 0.007
Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 19/150 (12%)
Query: 11 TAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP 70
+A P + A P ++ +P S + P+ +AT P + +AP PP
Sbjct: 424 SATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSAT----PPPQAPPPLAAPPLQLAKPPP 478
Query: 71 PPP-----PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQ-P 124
P PP + SP A P +A S + S A P P+ PP A+P Q P
Sbjct: 479 QAPPALATPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVP 535
Query: 125 PAPEEREEPPLPQPVAPALVPPAGGDSTVS 154
P+P P P AP P G D++VS
Sbjct: 536 PSP-----PASPTLQAPRRPPTPGPDTSVS 560
Score = 36.6 bits (83), Expect = 0.063
Identities = 68/308 (22%), Positives = 99/308 (32%), Gaps = 67/308 (21%)
Query: 11 TAASPGEGGAGEAEPEMEPIPGSEAGTD-----PLPVTATEASVPDGETDGQQSAPQADE 65
+ +S E E P P + G L +AT S P + P+A
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-- 256
Query: 66 PPLPPPPPPPG-ELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQP 124
P P P P G + R P+ P +A L ++ S A P P PPSP++PP
Sbjct: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPLATPS--PSAPPSPSAPPSLQ 313
Query: 125 PAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKL 184
P +P PP+ +++ L + F L
Sbjct: 314 TLP------------SPPATPPSQATTSLGS----------------PTLQATHSF---L 342
Query: 185 FSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPS 244
S L L+ P P P + P A P P P
Sbjct: 343 PSPPLSPLATP-PPQAPPALALPPLQAPPSPPASP--------------------PLSPL 381
Query: 245 PVPHPEL--SLAESLWTS--KPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRK 300
P P+ +LA L + PPP AP+ PP + + + P P + P +
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 301 MYREEPTS 308
+ P S
Sbjct: 442 VPPSPPAS 449
Score = 36.6 bits (83), Expect = 0.063
Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 11/125 (8%)
Query: 4 VAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGE--TDGQQSAP 61
+AA A P + A P ++ +P A + AS+P T Q+ P
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525
Query: 62 QADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPP 121
P L PP PP P L+A + +++ + P+ L P P PP
Sbjct: 526 VLAAPLLQVPPSPPAS---------PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576
Query: 122 EQPPA 126
+ P+
Sbjct: 577 SRSPS 581
Score = 36.2 bits (82), Expect = 0.082
Identities = 55/210 (26%), Positives = 78/210 (37%), Gaps = 29/210 (13%)
Query: 61 PQADEPPLPPPPPPPGELA--RSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPA 118
P+ P PPPP P L + AVG + AE + A +AP+ GP
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT------ 80
Query: 119 SPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSE--VRVTLDHIIEDALVV 176
+PPA E P + +P V G S ++ P + +R++ + +
Sbjct: 81 -RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139
Query: 177 SFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKC--E 234
L +G D S GP P T P AM +S GTEV
Sbjct: 140 EAPKRSALSAGARRDTS---GP--TPGTPSP---------AMARRSRA--AGTEVGLPRP 183
Query: 235 ANGAVPDDPSPVPHPELSLAESLWTSKPPP 264
A A P P+ P +S A T++P P
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSP 213
Score = 36.2 bits (82), Expect = 0.082
Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 8/97 (8%)
Query: 68 LPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAA---AAPQGGPELPPSPASPPE-- 122
L P PPPP + S GP+L + E + P+GG P P +
Sbjct: 568 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627
Query: 123 QPPAPEEREEPPLP---QPVAPALVPPAGGDSTVSQL 156
P A PPL P AP PPA G + L
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 54.3 bits (129), Expect = 3e-07
Identities = 82/320 (25%), Positives = 119/320 (37%), Gaps = 47/320 (14%)
Query: 43 TATEASVPDGETDGQQSAPQADEPPLPPPP-------PPPGELARSPEAVGPEL-EAEEK 94
T A VP G + GQ + E PPPP PP G A E+ +A ++
Sbjct: 653 TLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQ 712
Query: 95 LSVRVAESAAAAPQGGPE--------------LPPSPASPPEQ--PPAPEEREEPPLPQP 138
+R ++ A +P P +PP P P Q P P E E P P
Sbjct: 713 ECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGP 772
Query: 139 VAPALVPP-----AGGDSTVSQLI-PGSE---VRVTLDHIIEDALVVSFRFGEKLFS-GV 188
+P VPP G T S L+ PGS R++ SF K + V
Sbjct: 773 ASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQV 832
Query: 189 LMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPH 248
+ R GP +P+ K+ +P + + + EA P++P+P+P
Sbjct: 833 IQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQS--PEEPTPLPV 890
Query: 249 PEL-------SLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKR-PKRK 300
P L + A T +P P + A P F + N PPPR R P+R
Sbjct: 891 PLLLPPPSTPAPAAPTATVRPMP---QAALDPKANFSTNNSNPGARPPPPRATARLPQRG 947
Query: 301 MYREEPTSIMNAIKLRPRQV 320
+ P + A K++ V
Sbjct: 948 CPGDGPEAGRPADKIQMAMV 967
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/143 (30%), Positives = 57/143 (39%), Gaps = 15/143 (10%)
Query: 13 ASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPP 72
AS G E E E + + T+ +P TEA+ G+ + A + P P PP
Sbjct: 707 ASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP 766
Query: 73 PPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREE 132
PP E +P P EA + A P P PPSP++PP P E+ EE
Sbjct: 767 TPPPEDIPAPTEPTPASEA----------TGAPTP---PPAPPSPSAPPPVVPKEEKEEE 813
Query: 133 PPLPQPV--APALVPPAGGDSTV 153
PV PPA + V
Sbjct: 814 TAAAPPVEEGEEQKPPAAEELAV 836
Score = 36.2 bits (82), Expect = 0.082
Identities = 30/118 (25%), Positives = 41/118 (34%), Gaps = 16/118 (13%)
Query: 41 PVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVA 100
P+ T+ P E +AP PP PPPP + +P+ G + + A
Sbjct: 958 PIQVTKVHEPPRE----DAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPA 1013
Query: 101 ESAAAAPQGGP----ELPPSPASPP--------EQPPAPEEREEPPLPQPVAPALVPP 146
+ A P P E P PP PP + P P P A + PP
Sbjct: 1014 DKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPP 1071
Score = 33.5 bits (75), Expect = 0.53
Identities = 38/130 (29%), Positives = 43/130 (33%), Gaps = 22/130 (16%)
Query: 21 GEAEPEMEPIPGSEAGTDPLPVT-ATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELA 79
G P E IP A T+P P + AT A P P P PPP P E
Sbjct: 764 GPPTPPPEDIP---APTEPTPASEATGAPTPP---------PAPPSPSAPPPVVPKEEKE 811
Query: 80 RSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPV 139
A P E EE+ E A + A P + EE EE P
Sbjct: 812 EETAAAPPVEEGEEQKPPAAEELA---------VDTGKAEEPVKSECTEEAEEGPAKGKD 862
Query: 140 APALVPPAGG 149
A A A G
Sbjct: 863 AEAAEATAEG 872
Score = 33.1 bits (74), Expect = 0.69
Identities = 35/131 (26%), Positives = 51/131 (38%), Gaps = 30/131 (22%)
Query: 47 ASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAA 106
A++P + P+ D P P PP P P+ + PE +A ++ ++
Sbjct: 954 AAIPPIQVTKVHEPPREDAAPTKPAPPAP----PPPQNLQPESDAPQQ--------PGSS 1001
Query: 107 PQGGPELPPSPASPPEQPP------APEERE---EPP-----LPQPVAPALV----PPAG 148
P+G P PA + P A E ++ +PP LP PV P V P A
Sbjct: 1002 PRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAP 1061
Query: 149 GDSTVSQLIPG 159
S S PG
Sbjct: 1062 DPSAFSYAPPG 1072
Score = 32.3 bits (72), Expect = 1.2
Identities = 33/117 (28%), Positives = 41/117 (35%), Gaps = 7/117 (5%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEA 84
P +E +P PL T A D D +S EP PP PP E
Sbjct: 108 PRLELLPDPLLRPSPLLATGQPAGSEDLTKD--RSLTGKLEPVSPPSPP---HTDPELEL 162
Query: 85 VGPELEAEEKLS--VRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPV 139
V P L EE + RV Q +L E+ P E E+P P P+
Sbjct: 163 VPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPI 219
Score = 32.3 bits (72), Expect = 1.2
Identities = 27/102 (26%), Positives = 35/102 (34%), Gaps = 11/102 (10%)
Query: 206 FPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPELSLAESLWTSKPPPL 265
FP ++ EA + N + E + N + + P PH E + KPP
Sbjct: 696 FPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPAT 755
Query: 266 FHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPT 307
GA PPP P PPP I P E T
Sbjct: 756 L--GADGPPP---------GPPTPPPEDIPAPTEPTPASEAT 786
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 54.3 bits (129), Expect = 3e-07
Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 59 SAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPA 118
S + PP PPPPPP P ++GP V++ + + Q P PP P
Sbjct: 1951 SPSSPETPPPPPPPPPLPPAPPQPSSMGP---------VKIPNTVSTPLQAPPPTPPPPP 2001
Query: 119 SPPEQPPAPEEREEPPLPQPVAPALV 144
PP PP P PP P P AP V
Sbjct: 2002 PPPPPPPPP-----PPPPPPSAPPQV 2022
Score = 52.0 bits (123), Expect = 1e-06
Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 60 APQADEPPLPPPPPPPGELAR-SPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPA 118
+P + E P PPPPPPP A P ++GP K+ V+ A P P PP P
Sbjct: 1951 SPSSPETPPPPPPPPPLPPAPPQPSSMGPV-----KIPNTVSTPLQAPPPTPPPPPPPPP 2005
Query: 119 SPPEQPPAPEEREEPPLPQPVA 140
PP PP P P + PV+
Sbjct: 2006 PPPPPPPPPPPSAPPQVQLPVS 2027
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/94 (28%), Positives = 38/94 (40%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEA 84
P P P P P + +P+ + Q+ P PP PPPPPPP P +
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPS 2017
Query: 85 VGPELEAEEKLSVRVAESAAAAPQGGPELPPSPA 118
P+++ L + + S P P LPP A
Sbjct: 2018 APPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLA 2051
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 50 PDGETDGQQSAPQADEPPLPPPPPPPGELA--RSPEAVGPELEAEEKLSVRVAESAAAAP 107
P + + P PPLPP PP P + + P V L+A P
Sbjct: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP---PPPPPPPP 2005
Query: 108 QGGPELPPSPASPPEQPPAPEEREEPPLP----QPVAPALVPP 146
P PP P S P Q P + P P QPV +PP
Sbjct: 2006 PPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
Score = 34.7 bits (78), Expect = 0.24
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 11/98 (11%)
Query: 35 AGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEK 94
AG P +AT S P + P PP PPPPPPP S G + E + K
Sbjct: 3088 AGMLGFPTSAT--SSPALSLSSAPTKPLLQTPPPPPPPPPP---PPSSSLSGQQTEQQNK 3142
Query: 95 LSVRVAESAAAAPQGGPELPPS--PASPPEQPPAPEER 130
S E P ++ A+ PE+ P EE+
Sbjct: 3143 ES----EKKQTKPNKVKKIKEEELEATKPEKHPKKEEK 3176
Score = 33.1 bits (74), Expect = 0.69
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 29/101 (28%)
Query: 5 AAEAAATAASPGEGGAG------EAEPEM---------------EPIPGSEAGTDPLPVT 43
A AAA AAS G G + + EPE +P P S+ LP+
Sbjct: 2328 AKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLA 2387
Query: 44 ATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEA 84
+T + P T A P P PP P + R P A
Sbjct: 2388 STSSDPPQAST--------AQPQPQPQPPKQPQLIGRPPSA 2420
Score = 31.6 bits (70), Expect = 2.0
Identities = 35/126 (27%), Positives = 54/126 (42%), Gaps = 25/126 (19%)
Query: 52 GETDGQQSA--PQADE------PPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESA 103
G+TD ++A P A P +P P P P + SP+ PE AE+ +S
Sbjct: 2323 GQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKT--SPK---PEYPAEKP-----KQSD 2372
Query: 104 AAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQ-PVAPALV--PPAGGDSTVSQLIPGS 160
+ P G + AS PP + P PQ P P L+ PP+ + V P S
Sbjct: 2373 PSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPV----PSS 2428
Query: 161 EVRVTL 166
+++++
Sbjct: 2429 PLQISM 2434
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/159 (28%), Positives = 56/159 (35%), Gaps = 34/159 (21%)
Query: 24 EPEMEPIPGSEAGTDPLPVTAT-EASVPDGETDGQQSAPQADEPPLPPP---------PP 73
+PE P G P P E P G Q + P +P PPP PP
Sbjct: 77 KPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPP 136
Query: 74 PPGELARSPEAVGPELEA-------------EEKLSVRVAESAAAAPQG----------G 110
PPG+ R P G + + +E R A S PQG G
Sbjct: 137 PPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQG 196
Query: 111 PELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGG 149
P P P PP P++ + PP +P P PP GG
Sbjct: 197 PPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPP-PPPQGG 234
Score = 52.8 bits (125), Expect = 8e-07
Identities = 46/162 (28%), Positives = 57/162 (35%), Gaps = 29/162 (17%)
Query: 29 PIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP---------PPPPGELA 79
P G+++ P P E P G Q P +P PPP PPPPG+
Sbjct: 62 PQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPE 121
Query: 80 RSPEAVG--------PELEAEEKLSVRVAESAAAAPQGG-PELPP-----------SPAS 119
R P G P + E +S P G PE PP SP
Sbjct: 122 RPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPG 181
Query: 120 PPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSE 161
P+ PP E + P P P PPAGG+ Q P +
Sbjct: 182 KPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGK 223
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 15/119 (12%)
Query: 46 EASVPDGETDGQQSAPQADEPPLPPP---------PPPPGELARSPEAVGPELEAEEKLS 96
E P G Q+ P +P PPP PPPPG+ P G + +
Sbjct: 37 EGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPP-- 94
Query: 97 VRVAESAAAAPQGGPE---LPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDST 152
+ PQGG + PP P P PP + P P P P PP GG+ +
Sbjct: 95 -HPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQS 152
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/178 (25%), Positives = 65/178 (36%), Gaps = 23/178 (12%)
Query: 1 MAAVAAEAAATAASPGEGGAGE-------AEPE-MEPIPGSEAGTDPLPVTATEASVPDG 52
+ +VA A ++A S E + E +PE P G++ P P + P G
Sbjct: 5 LLSVALLALSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQG 64
Query: 53 ETDGQQSAPQADEPPLPPP---------PPPPGELARSPEAVGPELEAEEKLSVRVAESA 103
Q P +P PP PP PG+ R P G + + +
Sbjct: 65 GNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPP---PPGKPE 121
Query: 104 AAAPQGGPEL---PPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
PQGG + PP P P PP + + P P P P PP G+ + S P
Sbjct: 122 RPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP 179
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 20/121 (16%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATE-ASVPDGETDGQQSAPQADEPPLPPPPP 73
P +GG P P PG G P + A P G+ G P E P PP
Sbjct: 145 PPQGGNQSQGPP--PHPGKPEGPPPQEGNKSRSARSPPGKPQG----PPQQEGNKPQGPP 198
Query: 74 PPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEP 133
PPG+ P A G + + A P G P+ PP P +PP P + ++P
Sbjct: 199 PPGKPQGPPPAGGNPQQPQ------------APPAGKPQGPPPPPQGG-RPPRPAQGQQP 245
Query: 134 P 134
P
Sbjct: 246 P 246
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/303 (26%), Positives = 106/303 (34%), Gaps = 29/303 (9%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPP- 73
P E + A P ++ P S T PL + A P + P + PP P P P
Sbjct: 511 PLETQSSLAPPSLQTPPASLT-TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569
Query: 74 --PPGELARSPEAVGPELEAEEKLSVRVAESAAAAP--QGGPELPPSP-ASPPEQPPAPE 128
PP L P PE + A A A+P QG P P SP A+PP P AP
Sbjct: 570 QAPPSPLTTPP----PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP--PQAPP 623
Query: 129 EREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGV 188
PPL P +P PP +T S P + H+++ F V
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNA----LAVHLLQAP------FSPPPSPPV 673
Query: 189 LMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPH 248
S P P + P + A PLQ + + P P P+
Sbjct: 674 QAPFSPPASPPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732
Query: 249 PELSLAESLWTSKPPPLFHEGAPYP--PPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEP 306
P L + S S PP+ P P PPL Q P PP P K + P
Sbjct: 733 PPLQVPPSPPAS--PPMSPSATPPPRVPPLLAAPPL-QVPPSPPASLPMSPLAKPPPQAP 789
Query: 307 TSI 309
++
Sbjct: 790 PAL 792
Score = 50.4 bits (119), Expect = 4e-06
Identities = 42/151 (27%), Positives = 55/151 (36%), Gaps = 11/151 (7%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
A P + A P ++ P A P+ P+ A + P PP
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA------LAVHLLQAPFSPP 668
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPS--PASPPEQPP--AP 127
P PP + SP A P + + S AA P P PP+ P SP PP AP
Sbjct: 669 PSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 128 EEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
PPL P +P PP +T +P
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Score = 49.3 bits (116), Expect = 9e-06
Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 19/148 (12%)
Query: 11 TAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP 70
+A P + A P ++ +P S + P+ +AT P + +AP PP PP
Sbjct: 688 SATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSAT----PPPQAPPPLAAPPLQVPPSPP 742
Query: 71 PPPPPGELARSPEAV-----GPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQ-- 123
PP A P V P L+ + S A P P+ PP+ A+PP Q
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP--PQAPPALATPPLQAL 800
Query: 124 --PPAPEEREEPPLPQ---PVAPALVPP 146
PPA + P P P++P PP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPP 828
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 17/160 (10%)
Query: 1 MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDG-ETDGQQS 59
+ ++A TA++P E P P P P P+T P T Q+
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCP---LQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 60 APQADEPPLP------------PPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAP 107
P PPL PPP P LA P P A LS S A
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Query: 108 QGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPA 147
L +P SPP PP + PP PV+P+ PP+
Sbjct: 655 ALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPS 693
Score = 42.7 bits (99), Expect = 9e-04
Identities = 47/156 (30%), Positives = 63/156 (40%), Gaps = 18/156 (11%)
Query: 11 TAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP 70
+A P + A P ++ +P S + P+ +AT P +AP PP PP
Sbjct: 719 SATPPPQAPPPLAAPPLQ-VPPSPPASPPMSPSAT----PPPRVPPLLAAPPLQVPPSPP 773
Query: 71 PPPPPGELARSPEAVGPELEAE--EKLSVRVAESAAAAP-QGGPELPPSP-ASPPEQPP- 125
P LA+ P P L + L A AP LP SP A+PP Q P
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833
Query: 126 --APEEREEPPLPQPVAPAL-----VPPAGGDSTVS 154
A + PP P P +P L P G D++VS
Sbjct: 834 VLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVS 868
Score = 41.6 bits (96), Expect = 0.002
Identities = 57/212 (26%), Positives = 81/212 (38%), Gaps = 24/212 (11%)
Query: 61 PQADEPPLPPPPPPPGELA--RSPEAVGPELEAEEKLSVRVAESAAAAPQGGP--ELPPS 116
P+ P PPPP P L + AVG + AE + A +AP+ GP S
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 117 PASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSE--VRVTLDHIIEDAL 174
+P +PPA E P + +P V G S ++ P + +R++ + +
Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146
Query: 175 VVSFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKC- 233
L +G D S GP P T P AM +S GTEV
Sbjct: 147 ATEAPKRSALSAGARRDTS---GP--TPGTPSP---------AMARRSRA--AGTEVGLP 190
Query: 234 -EANGAVPDDPSPVPHPELSLAESLWTSKPPP 264
A A P P+ P +S A T++P P
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222
Score = 37.0 bits (84), Expect = 0.048
Identities = 41/166 (24%), Positives = 56/166 (33%), Gaps = 31/166 (18%)
Query: 11 TAASPGEGGAGEAEPEMEPIPGSEAGTD-----PLPVTATEASVPDGETDGQQSAPQADE 65
+ +S E E P P + G L +AT S P + P+A
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-- 265
Query: 66 PPLPPPPPPPG-ELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPE------------ 112
P P P P G + R P+ P +A L + A G +
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325
Query: 113 -----LPPSP--ASP----PEQPPAPEEREEPPLPQPVAPALVPPA 147
LPPSP A+P P P AP + P P P+ PP+
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Score = 36.2 bits (82), Expect = 0.082
Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 8/97 (8%)
Query: 68 LPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAA---AAPQGGPELPPSPASPPE-- 122
L P PPPP + S GP+L + E + P+GG P P +
Sbjct: 876 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935
Query: 123 QPPAPEEREEPPLP---QPVAPALVPPAGGDSTVSQL 156
P A PPL P AP PPA G + L
Sbjct: 936 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972
Score = 35.8 bits (81), Expect = 0.11
Identities = 77/334 (23%), Positives = 109/334 (32%), Gaps = 59/334 (17%)
Query: 5 AAEAAATAASPG-----EGGAGEAEPEMEPIPGSEAG-TDPLPVTATEASVPDGETDGQQ 58
A+E + T SP G G P + S + P + P Q
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 59 SAP---QADEPPLPPPP-----PPPGELARSPEA-----------VGPELEAEEKLSVRV 99
P QA PP PP P G L+ SP A V P A L +
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331
Query: 100 AESAAAAPQGGPELPPSPA---------SPPEQPP--APEEREEPPLPQPVAPALVPPAG 148
S A P PPSP+ SPP PP AP PP+ P + +PP
Sbjct: 332 PPSPPLATPL-PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI- 389
Query: 149 GDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGV--LMDLSKRFGPHGIPVTVF 206
V + ++ + +L + G + +S R +
Sbjct: 390 ---QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL---TS 443
Query: 207 PKREYKDKPEAMPLQSN-TFQEGTEVKCEANGAVPDDPSPVPHPELSLAESLWTSKP--- 262
P R P++ PLQ+ + ++ + AV SP+ L SL + P
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503
Query: 263 ------PPLFHEGAPYPPPLFIRDTYNQSIPQPP 290
PPL + + PP L T S+ PP
Sbjct: 504 LSSLIMPPLETQSSLAPPSL---QTPPASLTTPP 534
Score = 35.8 bits (81), Expect = 0.11
Identities = 70/338 (20%), Positives = 107/338 (31%), Gaps = 76/338 (22%)
Query: 3 AVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVT-------ATEASVPDGETD 55
A+ +++ A+P G + P+P + PLP T AT +
Sbjct: 295 ALGPLSSSPLATPSPSGT-----KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349
Query: 56 GQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP 115
S PP PP P + P P L+ + V + ++ + + PP
Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL-----QAPP 404
Query: 116 SP------------ASPPEQP-----PAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIP 158
SP SP Q + + L P PA PP +P
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Query: 159 GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKD----K 214
S T LS P P+T+ P +
Sbjct: 465 ASPPLQT-------------------------SLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 215 PEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPP 274
P+A PL S A ++ P+ + P L E+L + PPPL AP
Sbjct: 500 PQA-PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL---ENLPSLAPPPLQTASAPLTT 555
Query: 275 PLFIRDTYNQSIPQPPPRKIKRPKRKMYR---EEPTSI 309
P + ++ P P P ++ P + E P+SI
Sbjct: 556 P------HLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Score = 35.0 bits (79), Expect = 0.18
Identities = 28/117 (23%), Positives = 44/117 (37%), Gaps = 11/117 (9%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGE--TDGQQSAPQADEPPLP 69
A P + A P ++ +P A + AS+P T Q+ P P L
Sbjct: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 70 PPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPA 126
PP PP P L+A + +++ + P+ L P P PP + P+
Sbjct: 842 VPPSPPAS---------PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
Length = 1086
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/316 (25%), Positives = 118/316 (37%), Gaps = 47/316 (14%)
Query: 43 TATEASVPDGETDGQQSAPQADEPPLPPPP-------PPPGELARSPEAVGPEL-EAEEK 94
T A VP G + GQ + E PPPP PP G A E+ +A ++
Sbjct: 731 TLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQ 790
Query: 95 LSVRVAESAAAAPQGGPE--------------LPPSPASPPEQ--PPAPEEREEPPLPQP 138
+R ++ A +P P +PP P P Q P P E E P P
Sbjct: 791 ECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGP 850
Query: 139 VAPALVPP-----AGGDSTVSQLI-PGSE---VRVTLDHIIEDALVVSFRFGEKLFS-GV 188
+P VPP G T S L+ PGS R++ SF K + V
Sbjct: 851 ASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQV 910
Query: 189 LMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPH 248
+ R GP +P+ K+ +P + + + EA P++P+P+P
Sbjct: 911 IQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQS--PEEPTPLPV 968
Query: 249 PEL-------SLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKR-PKRK 300
P L + A T +P P + A P F + N PPPR R P+R
Sbjct: 969 PLLLPPPSTPAPAAPTATVRPMP---QAALDPKANFSTNNSNPGARPPPPRATARLPQRG 1025
Query: 301 MYREEPTSIMNAIKLR 316
+ P + A K++
Sbjct: 1026 CPGDGPEAGRPADKIQ 1041
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 53.5 bits (127), Expect = 5e-07
Identities = 41/137 (29%), Positives = 44/137 (32%), Gaps = 31/137 (22%)
Query: 12 AASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPP 71
A P EG A + + P P S PLP S P + PPLPPP
Sbjct: 630 ALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLS------PAPPMPPVSAGPPLPPP 683
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEERE 131
PPPP L A GP PP P P P P
Sbjct: 684 PPPPPPLPPPSSA-------------------------GPPPPPPPPPLPNSPAPPNPGG 718
Query: 132 EPPLPQPVAPALVPPAG 148
PP P P A PP G
Sbjct: 719 PPPAPPPPGLAPPPPPG 735
Score = 30.4 bits (67), Expect = 4.5
Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 5/108 (4%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP--PPP 72
P G G P P+P AG P +P + G P PPLP P P
Sbjct: 657 PLPSGLGSLSPA-PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP--PPLPNSPAP 713
Query: 73 PPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
P PG +P G L + S++ P+ P P P
Sbjct: 714 PNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 53.5 bits (127), Expect = 5e-07
Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 34/187 (18%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP----P 70
P GG P + + G++ + PLP + P P PP P P
Sbjct: 319 PSRGGNQLPRPPI--VGGNKGRSGPLPPVPLGIAPPP---------PTPRGPPPPGRGGP 367
Query: 71 PPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEER 130
PPPPP RS P A GGP +PP P PP P +
Sbjct: 368 PPPPPPATGRSGPLPPPPPGA-----------------GGPPMPPPPPPPPPPPSSGNGP 410
Query: 131 EEPPLPQPVAPA--LVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGV 188
PPLP + PA L P G + + Q+ G ++ T AL + E L +
Sbjct: 411 APPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGAL 470
Query: 189 LMDLSKR 195
+ + KR
Sbjct: 471 MHVMQKR 477
Score = 48.5 bits (114), Expect = 2e-05
Identities = 42/136 (30%), Positives = 46/136 (33%), Gaps = 38/136 (27%)
Query: 65 EPPLPPPPPPP--GELARSPEAVGPELEAEEKLSVRVAESAAAAP---------QGGPEL 113
+ PLPPPPPP G P VG L A P +GGP
Sbjct: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPP 369
Query: 114 PPSPAS--------------------PPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTV 153
PP PA+ PP PP P P P P+ PALVP G
Sbjct: 370 PPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGG----- 424
Query: 154 SQLIPGSEVRVTLDHI 169
L PG LD I
Sbjct: 425 --LAPGGGRGALLDQI 438
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 53.5 bits (127), Expect = 5e-07
Identities = 74/298 (24%), Positives = 100/298 (33%), Gaps = 48/298 (16%)
Query: 23 AEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSP 82
AE M EA P P+T S P S P PPL PPPPPP P
Sbjct: 387 AEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP----PPLCPPPPPPVSPPPLP 442
Query: 83 EAVGPELEAEEKLSVR-VAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAP 141
P + E++ S V + + +G P L PS + E A E PP P P
Sbjct: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTA 502
Query: 142 ALVPPAGGDSTVSQLIPG-SEVRVTLDHII----EDALVVSFRF-GEKLFSGVLMDLSKR 195
PP + + +R + ++ + RF E +++S
Sbjct: 503 TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPV 562
Query: 196 FGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPELSLAE 255
P P+T P + P P ++ T P P P+P S+
Sbjct: 563 LRP---PITTSPPVPQEPAPVPSPPRAPT--------------PPSTPVPLPEKRRSILR 605
Query: 256 S---LWTS----KPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEP 306
WTS PPP AP PPP P PPP +R + P
Sbjct: 606 EPTFRWTSLTRELPPP---PPAPPPPP----------APSPPPAPATSSRRPLLLRAP 650
Score = 46.6 bits (109), Expect = 6e-05
Identities = 69/290 (23%), Positives = 88/290 (30%), Gaps = 49/290 (16%)
Query: 22 EAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARS 81
E E + E + G + E +P E + + P PP P PPPP + S
Sbjct: 364 EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTS 423
Query: 82 PEAVGPELEAEEKLSVRVAESAAAAPQGGPELPP-SPASPPEQPPAPEEREEPPLPQPVA 140
P P P PP SP P PP P + E+ P PV
Sbjct: 424 PPP----------------------PLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461
Query: 141 PALVPPAGG--DSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGP 198
PA G T SQ R + S G GP
Sbjct: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATG---------------GP 506
Query: 199 HGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPELSLAESLW 258
TV PK K + + V + +DP P E+S
Sbjct: 507 PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPP 566
Query: 259 TSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRP-KRKMYREEPT 307
+ PP+ E AP P P P PP + P KR+ EPT
Sbjct: 567 ITTSPPVPQEPAPVPSP--------PRAPTPPSTPVPLPEKRRSILREPT 608
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 16/148 (10%)
Query: 20 AGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELA 79
AGE EP P+ P T ++P G G P PPPPPP +
Sbjct: 2205 AGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
Query: 80 RSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPV 139
S A P K RV+ + +P PA PP + P +E E P
Sbjct: 2265 SSGPASPPRQAIRVK---RVSTFSGRSP---------PAPPPYKAPRLDEDGEASEDTPQ 2312
Query: 140 APALVPPAGGDSTVSQLIPGSEVRVTLD 167
P L +GG S V P VR LD
Sbjct: 2313 VPGL--GSGGFSRVRMKTP--TVRGVLD 2336
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQ-GGPELPPSPAS 119
P PP P PPP P +R P + + +++ ES P G PE P
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP----- 677
Query: 120 PPEQPPAPEEREEP 133
PE PPA + EP
Sbjct: 678 EPEPPPADDSPAEP 691
Score = 38.1 bits (87), Expect = 0.022
Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 3/110 (2%)
Query: 25 PEMEPIPGSEAGTDPLPVTATEAS--VPDGETDGQQSAPQADEPPLP-PPPPPPGELARS 81
P P+ G G P P + + + +P + P+ P P P PPP A
Sbjct: 1872 PSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASP 1931
Query: 82 PEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEERE 131
P P+L SV A + + P PSP P + P E+ E
Sbjct: 1932 PLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDME 1981
Score = 37.7 bits (86), Expect = 0.028
Identities = 31/122 (25%), Positives = 40/122 (32%), Gaps = 7/122 (5%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPP 74
PG+GGAG E + P P G+ P + P AP L P P P
Sbjct: 2124 PGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEP 2183
Query: 75 PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPP 134
P+ ++ KL + A P + P P P AP PP
Sbjct: 2184 -------PKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPP 2236
Query: 135 LP 136
P
Sbjct: 2237 GP 2238
Score = 36.2 bits (82), Expect = 0.082
Identities = 32/122 (26%), Positives = 37/122 (30%), Gaps = 31/122 (25%)
Query: 61 PQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASP 120
P PP+P P P R+P + EK + E ELPP P +P
Sbjct: 566 PITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAP 625
Query: 121 P-----EQPPAPEEREE--------------------------PPLPQPVAPALVPPAGG 149
P PPAP PPL P AP PP
Sbjct: 626 PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPAD 685
Query: 150 DS 151
DS
Sbjct: 686 DS 687
Score = 35.8 bits (81), Expect = 0.11
Identities = 35/145 (24%), Positives = 52/145 (35%), Gaps = 21/145 (14%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPP 74
P + E+ P + P S P P+T ++ + E + ++ P+ PP P P
Sbjct: 448 PAQEEQEESPPPVVPATCSRKRGRP-PLTPSQRA----EREAARAGPEGTSPPTPTPSTA 502
Query: 75 PGELARSPEAVGPE------------LEAEEKLSVRVAESAAAAPQGGPELPPS-PASPP 121
G V P+ + S RV ++ P PP SP
Sbjct: 503 TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPV 562
Query: 122 EQPPAPEEREEPPLPQPVAPALVPP 146
+PP PP+PQ AP PP
Sbjct: 563 LRPPI---TTSPPVPQEPAPVPSPP 584
Score = 34.3 bits (77), Expect = 0.31
Identities = 48/219 (21%), Positives = 77/219 (35%), Gaps = 38/219 (17%)
Query: 60 APQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAES---AAAAPQGGPELPPS 116
AP+A EP PP P E P AVG V + A +P G P L
Sbjct: 673 APEAPEPEPPPADDSPAE--PEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG 730
Query: 117 PAS----------------PPEQPPAPEEREEPPLPQPVAP---------ALVPPAGGDS 151
P + P PP + + PP PQ + P +P +G +
Sbjct: 731 PQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEE 790
Query: 152 TVSQLIPGSEVRV-TLDHIIEDALVVSFRFGE----KLFSGVLMDLSKRFGPHGIPVTVF 206
+ L+ ++V++ +D + + S + +G + +S R +V
Sbjct: 791 KMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVE 850
Query: 207 PKREYKDKPEAM---PLQSNTFQEGTEVKCEANGAVPDD 242
KRE PE+ P + + +A VP+D
Sbjct: 851 AKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPED 889
Score = 31.6 bits (70), Expect = 2.0
Identities = 37/140 (26%), Positives = 47/140 (33%), Gaps = 26/140 (18%)
Query: 27 MEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADE--PPLPPPPPPPGELARSPEA 84
+ P P P T+ + VP + P + E PP P P PPP PE
Sbjct: 1919 LAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPP------PED 1972
Query: 85 VGPELEAEEKLSVRVA-----------------ESAAAAPQGGPELPPSPASPPEQPPAP 127
+GP+ E E +S A E AA G P +S E P
Sbjct: 1973 LGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPT- 2031
Query: 128 EEREEPPLPQPVAPALVPPA 147
P+ AP L P A
Sbjct: 2032 SRYIHFPVTVVSAPGLAPSA 2051
Score = 30.4 bits (67), Expect = 4.5
Identities = 78/317 (24%), Positives = 104/317 (32%), Gaps = 55/317 (17%)
Query: 9 AATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVP------------DGETDG 56
AA A GG G++ E E P S P+ V + P DG DG
Sbjct: 2009 AAGAMGSSHGGPGDSSEE-ESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDG 2067
Query: 57 QQSAPQADEPPLPPPPPPPGE---LARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPEL 113
S +A + P PP G A A G E L + + GGP
Sbjct: 2068 TDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVD-FVLKNLGGP-- 2124
Query: 114 PPSPASPPEQ--PPAPEEREEPPL---PQPVAPALVPPAGGDSTVSQLIPGSEVRV-TLD 167
A P E+ PPA PPL QP PA T + L VRV +L
Sbjct: 2125 GDGGAGPREESLPPA------PPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLG 2178
Query: 168 HIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQE 227
E + + + L + G VF K + +P P++
Sbjct: 2179 PAPEPPKPATSK----------IILVNKLG------QVFVKMAGEGEPVPPPVKQPPLPP 2222
Query: 228 GTEVKCEANGAVPDDPSPVPHPELSLAESLWTSKPPPL---FHEGAPYPPPLFIR----D 280
+ +P P P + + PPPL G PP IR
Sbjct: 2223 TISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVS 2282
Query: 281 TYN-QSIPQPPPRKIKR 296
T++ +S P PPP K R
Sbjct: 2283 TFSGRSPPAPPPYKAPR 2299
Score = 29.6 bits (65), Expect = 7.7
Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 12/112 (10%)
Query: 14 SPGEGGAGEAEPEMEPIPGSEAGTDPLPVTA---TEASVPDGETDGQQSAPQADEPPLPP 70
+P GA EA PE EP P ++ +P P S+P + AP P
Sbjct: 667 TPPPLGAPEA-PEPEPPPADDSPAEPEPRAVGRTNHLSLP-------RFAPVVTTPVKAE 718
Query: 71 PPPPPGE-LARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPP 121
P L+ P+ L+ + L ++ A PQ + PPSP P
Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 53.1 bits (126), Expect = 6e-07
Identities = 51/172 (29%), Positives = 66/172 (38%), Gaps = 22/172 (12%)
Query: 6 AEAAATAASPGEGGAGEAEPEMEP---IPGSEAGTDPLPVTATEASVPDGETDGQQSAPQ 62
A A+ SP E P EP P S P PV + V + + ++
Sbjct: 271 ATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330
Query: 63 ADEPPLPPPPPPPGELA--------RSPEAVGP-ELEAEEKLSVRVAESAAAAPQGGPEL 113
+ P P PP + R+PE P EL+A S R+ +S + A +
Sbjct: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390
Query: 114 PPSPASPPEQPPAPEEREEPPLPQPVAPALV-------PPAGGDSTVSQLIP 158
PP+P PP PP P PPLP P AP L PPAG T P
Sbjct: 391 PPAPPLPPPAPPLPP--PAPPLP-PAAPPLPCAQKAAHPPAGFTKTPKSSSP 439
Score = 49.7 bits (117), Expect = 7e-06
Identities = 65/239 (27%), Positives = 87/239 (36%), Gaps = 31/239 (12%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP---P 71
PG+ G P P PG P P + S P G + +P + PP PP
Sbjct: 130 PGQYGQDLLIPP--PPPG------PAPGPPQDISEPPGGSP--LPSPPSTAPPPPPLLLE 179
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEERE 131
PPPP +A P P LEA LS S+ + P +PP+P PP P
Sbjct: 180 PPPPPSMAPPPP---PVLEA---LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPP---- 229
Query: 132 EPPLPQPVAPALVPPAGGDSTVSQLIP-GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLM 190
P+P P PA PA + ++L P G + D + + R
Sbjct: 230 --PVPAPAPPA---PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP--RSPAE 282
Query: 191 DLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHP 249
GP+ P FP+ P + S QE E + GA PS +P P
Sbjct: 283 PKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/142 (31%), Positives = 53/142 (37%), Gaps = 33/142 (23%)
Query: 10 ATAASPGEGGAGEAEPEMEPIPGS---EAGTDPLPVTATEASVPDGETDGQ--------Q 58
A A E GA + P P+P S + P A E P GE Q
Sbjct: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP-GELKATAPASPRLGQ 378
Query: 59 SAPQADE--------PPLPPPPPP-PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQG 109
S QADE PPLPPP PP P P A P + A+ AA P G
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP---------LPCAQKAAHPPAG 429
Query: 110 GPELPPSPA---SPPEQPPAPE 128
+ P S + P PP+PE
Sbjct: 430 FTKTPKSSSPALKPKPNPPSPE 451
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 240 PDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPP 291
P P P P P ++E S P P AP PPPL + S+ PPP
Sbjct: 141 PPPPGPAPGPPQDISEPPGGS-PLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191
Score = 32.3 bits (72), Expect = 1.2
Identities = 68/304 (22%), Positives = 92/304 (30%), Gaps = 56/304 (18%)
Query: 16 GEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPP 75
G G E E S+A + P AT T G +S+ A PP P
Sbjct: 712 GPAGQPEKPASQEVSTPSQARGEGSPSEATRLP-----TQGARSS--AAFPPKTSPGGGE 764
Query: 76 GELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPL 135
P L E + + AA G P P P +PPA + + L
Sbjct: 765 VPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELL 824
Query: 136 PQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKR 195
PV +V + L+ + R + AL G G L D S +
Sbjct: 825 RHPVTGEVVE----RGSPMALLLAARQRAQKGRSVGAAL------GRSSLPGSLRDHSHQ 874
Query: 196 --------FGPHGIP-----VTVFPKREYKDKPEAMPLQS------NTFQEGTEVKCEAN 236
F G P V PK KD P + + EGTE+ N
Sbjct: 875 AEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHN 934
Query: 237 GAVPDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKR 296
P+ +PV W P +G P P +S PP KR
Sbjct: 935 WTKPEPQAPV----------AWERVAPSNLPQGHPLP----------KSFSSPPSPSNKR 974
Query: 297 PKRK 300
+ +
Sbjct: 975 EEEE 978
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 53.1 bits (126), Expect = 6e-07
Identities = 51/172 (29%), Positives = 66/172 (38%), Gaps = 22/172 (12%)
Query: 6 AEAAATAASPGEGGAGEAEPEMEP---IPGSEAGTDPLPVTATEASVPDGETDGQQSAPQ 62
A A+ SP E P EP P S P PV + V + + ++
Sbjct: 271 ATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330
Query: 63 ADEPPLPPPPPPPGELA--------RSPEAVGP-ELEAEEKLSVRVAESAAAAPQGGPEL 113
+ P P PP + R+PE P EL+A S R+ +S + A +
Sbjct: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390
Query: 114 PPSPASPPEQPPAPEEREEPPLPQPVAPALV-------PPAGGDSTVSQLIP 158
PP+P PP PP P PPLP P AP L PPAG T P
Sbjct: 391 PPAPPLPPPAPPLPP--PAPPLP-PAAPPLPCAQKAAHPPAGFTKTPKSSSP 439
Score = 49.7 bits (117), Expect = 7e-06
Identities = 65/239 (27%), Positives = 87/239 (36%), Gaps = 31/239 (12%)
Query: 15 PGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPP---P 71
PG+ G P P PG P P + S P G + +P + PP PP
Sbjct: 130 PGQYGQDLLIPP--PPPG------PAPGPPQDISEPPGGSP--LPSPPSTAPPPPPLLLE 179
Query: 72 PPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEERE 131
PPPP +A P P LEA LS S+ + P +PP+P PP P
Sbjct: 180 PPPPPSMAPPPP---PVLEA---LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPP---- 229
Query: 132 EPPLPQPVAPALVPPAGGDSTVSQLIP-GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLM 190
P+P P PA PA + ++L P G + D + + R
Sbjct: 230 --PVPAPAPPA---PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP--RSPAE 282
Query: 191 DLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHP 249
GP+ P FP+ P + S QE E + GA PS +P P
Sbjct: 283 PKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/142 (31%), Positives = 53/142 (37%), Gaps = 33/142 (23%)
Query: 10 ATAASPGEGGAGEAEPEMEPIPGS---EAGTDPLPVTATEASVPDGETDGQ--------Q 58
A A E GA + P P+P S + P A E P GE Q
Sbjct: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP-GELKATAPASPRLGQ 378
Query: 59 SAPQADE--------PPLPPPPPP-PGELARSPEAVGPELEAEEKLSVRVAESAAAAPQG 109
S QADE PPLPPP PP P P A P + A+ AA P G
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP---------LPCAQKAAHPPAG 429
Query: 110 GPELPPSPA---SPPEQPPAPE 128
+ P S + P PP+PE
Sbjct: 430 FTKTPKSSSPALKPKPNPPSPE 451
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 240 PDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPP 291
P P P P P ++E S P P AP PPPL + S+ PPP
Sbjct: 141 PPPPGPAPGPPQDISEPPGGS-PLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191
Score = 32.3 bits (72), Expect = 1.2
Identities = 68/304 (22%), Positives = 92/304 (30%), Gaps = 56/304 (18%)
Query: 16 GEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPP 75
G G E E S+A + P AT T G +S+ A PP P
Sbjct: 712 GPAGQPEKPASQEVSTPSQARGEGSPSEATRLP-----TQGARSS--AAFPPKTSPGGGE 764
Query: 76 GELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPL 135
P L E + + AA G P P P +PPA + + L
Sbjct: 765 VPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELL 824
Query: 136 PQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKR 195
PV +V + L+ + R + AL G G L D S +
Sbjct: 825 RHPVTGEVVE----RGSPMALLLAARQRAQKGRSVGAAL------GRSSLPGSLRDHSHQ 874
Query: 196 --------FGPHGIP-----VTVFPKREYKDKPEAMPLQS------NTFQEGTEVKCEAN 236
F G P V PK KD P + + EGTE+ N
Sbjct: 875 AEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHN 934
Query: 237 GAVPDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKR 296
P+ +PV W P +G P P +S PP KR
Sbjct: 935 WTKPEPQAPV----------AWERVAPSNLPQGHPLP----------KSFSSPPSPSNKR 974
Query: 297 PKRK 300
+ +
Sbjct: 975 EEEE 978
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,264,326
Number of Sequences: 37866
Number of extensions: 1900957
Number of successful extensions: 39545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 745
Number of HSP's successfully gapped in prelim test: 1910
Number of HSP's that attempted gapping in prelim test: 14146
Number of HSP's gapped (non-prelim): 13811
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.