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Search of human proteins with 153791755
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791755 cyclin domain containing [Homo sapiens]
(350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791755 cyclin domain containing [Homo sapiens] 710 0.0
gi|161377472 cyclin A1 isoform c [Homo sapiens] 100 3e-21
gi|161377470 cyclin A1 isoform c [Homo sapiens] 100 3e-21
gi|161377468 cyclin A1 isoform b [Homo sapiens] 100 3e-21
gi|4502611 cyclin A1 isoform a [Homo sapiens] 100 3e-21
gi|4502613 cyclin A [Homo sapiens] 97 2e-20
gi|4757930 cyclin B2 [Homo sapiens] 95 8e-20
gi|14327896 cyclin B1 [Homo sapiens] 92 9e-19
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 87 2e-17
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 86 5e-17
gi|16950655 cyclin D1 [Homo sapiens] 69 5e-12
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 65 9e-11
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 63 3e-10
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 63 3e-10
gi|17318565 cyclin E2 [Homo sapiens] 62 8e-10
gi|4502617 cyclin D2 [Homo sapiens] 62 1e-09
gi|197276674 cyclin J isoform 1 [Homo sapiens] 62 1e-09
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 60 2e-09
gi|4757936 cyclin G2 [Homo sapiens] 59 8e-09
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 57 2e-08
gi|118572588 cyclin F [Homo sapiens] 50 3e-06
gi|5802992 cyclin I [Homo sapiens] 50 4e-06
gi|40805832 cyclin G1 [Homo sapiens] 48 1e-05
gi|4757934 cyclin G1 [Homo sapiens] 48 1e-05
gi|197276676 cyclin J isoform 3 [Homo sapiens] 47 3e-05
gi|40254889 cyclin J isoform 2 [Homo sapiens] 44 3e-04
gi|89886237 cyclin I family, member 2 [Homo sapiens] 41 0.002
gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo sapiens] 35 0.077
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 35 0.077
gi|24308303 SH3-binding domain protein 5-like [Homo sapiens] 35 0.077
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 710 bits (1832), Expect = 0.0
Identities = 350/350 (100%), Positives = 350/350 (100%)
Query: 1 MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDL 60
MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDL
Sbjct: 1 MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDL 60
Query: 61 FESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPRE 120
FESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPRE
Sbjct: 61 FESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPRE 120
Query: 121 ALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGV 180
ALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGV
Sbjct: 121 ALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGV 180
Query: 181 TSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF 240
TSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF
Sbjct: 181 TSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF 240
Query: 241 THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP 300
THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP
Sbjct: 241 THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP 300
Query: 301 VDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK 350
VDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK
Sbjct: 301 VDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK 350
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Query: 94 DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152
D+ +Y + Y + + E P+ + +QP +T R L+ WL+ V ++ L E
Sbjct: 160 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 219
Query: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212
+L L VN LDRFL+ V QL+G ++L+A K E++PP V + + + ++++Q
Sbjct: 220 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 279
Query: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272
L +E ++L L F L PT + FL + + + + LA+ VAELSL +
Sbjct: 280 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 331
Query: 273 Y-AFTSYSPSLLAICCLALAD 292
F Y PSL+A LA+
Sbjct: 332 ADPFLKYLPSLIAAAAFCLAN 352
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Query: 94 DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152
D+ +Y + Y + + E P+ + +QP +T R L+ WL+ V ++ L E
Sbjct: 160 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 219
Query: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212
+L L VN LDRFL+ V QL+G ++L+A K E++PP V + + + ++++Q
Sbjct: 220 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 279
Query: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272
L +E ++L L F L PT + FL + + + + LA+ VAELSL +
Sbjct: 280 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 331
Query: 273 Y-AFTSYSPSLLAICCLALAD 292
F Y PSL+A LA+
Sbjct: 332 ADPFLKYLPSLIAAAAFCLAN 352
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Query: 94 DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152
D+ +Y + Y + + E P+ + +QP +T R L+ WL+ V ++ L E
Sbjct: 203 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 262
Query: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212
+L L VN LDRFL+ V QL+G ++L+A K E++PP V + + + ++++Q
Sbjct: 263 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 322
Query: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272
L +E ++L L F L PT + FL + + + + LA+ VAELSL +
Sbjct: 323 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 374
Query: 273 Y-AFTSYSPSLLAICCLALAD 292
F Y PSL+A LA+
Sbjct: 375 ADPFLKYLPSLIAAAAFCLAN 395
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Query: 94 DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152
D+ +Y + Y + + E P+ + +QP +T R L+ WL+ V ++ L E
Sbjct: 204 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 263
Query: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212
+L L VN LDRFL+ V QL+G ++L+A K E++PP V + + + ++++Q
Sbjct: 264 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 323
Query: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272
L +E ++L L F L PT + FL + + + + LA+ VAELSL +
Sbjct: 324 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 375
Query: 273 Y-AFTSYSPSLLAICCLALAD 292
F Y PSL+A LA+
Sbjct: 376 ADPFLKYLPSLIAAAAFCLAN 396
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 97.4 bits (241), Expect = 2e-20
Identities = 69/249 (27%), Positives = 116/249 (46%), Gaps = 37/249 (14%)
Query: 72 ESPSAARGGSPLPGPAQPVAQLD--------------------------LQTFRDYGQSC 105
E A LPGP +P+ LD + DY +
Sbjct: 123 EDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDI 182
Query: 106 YAFRKAQESHFHPREA-LARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRF 164
+ + + E P+ + +QP +T R L+ WL+ V ++ L E+L L VN +DRF
Sbjct: 183 HTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF 242
Query: 165 LTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKL 224
L++ V QL+G ++L+A K E++PP V + + + ++++Q+ +E +VL L
Sbjct: 243 LSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
Query: 225 HFTLGAPTISFFL-EHFTHARVEAGQAEASEALEAQALARGVAELSLADY-AFTSYSPSL 282
F L APT++ FL ++F H + + ++LA + ELSL D + Y PS+
Sbjct: 303 TFDLAAPTVNQFLTQYFLH--------QQPANCKVESLAMFLGELSLIDADPYLKYLPSV 354
Query: 283 LAICCLALA 291
+A LA
Sbjct: 355 IAGAAFHLA 363
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 95.1 bits (235), Expect = 8e-20
Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 8/168 (4%)
Query: 128 VTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIAC 187
+ R L+ WL+ VH +F L E+L + V +DRFL PV+ QL+G+T+LL+A
Sbjct: 161 INGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLAS 220
Query: 188 KQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEA 247
K E+ P ++ + + A++ Q+ +E ++L +L F LG P HF +A
Sbjct: 221 KYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRP----LPLHFLRRASKA 276
Query: 248 GQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRML 295
G+ + +E LA+ + EL+L DY Y PS +A L+ ++L
Sbjct: 277 GEVD----VEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVL 320
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 91.7 bits (226), Expect = 9e-19
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 12/198 (6%)
Query: 100 DYGQSCYAFRKA--QESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLT 157
+Y + YA+ + +E P+ L R+ VT R L+ WL+ V +F L E++ +T
Sbjct: 169 EYVKDIYAYLRQLEEEQAVRPKYLLGRE--VTGNMRAILIDWLVQVQMKFRLLQETMYMT 226
Query: 158 VNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLE 217
V+ +DRF+ V QL+GVT++ IA K E++PP + + +++ Q+ +E
Sbjct: 227 VSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQME 286
Query: 218 CIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTS 277
+L L+F LG P HF + G+ + +E LA+ + EL++ DY
Sbjct: 287 MKILRALNFGLGRP----LPLHFLRRASKIGEVD----VEQHTLAKYLMELTMLDYDMVH 338
Query: 278 YSPSLLAICCLALADRML 295
+ PS +A LA ++L
Sbjct: 339 FPPSQIAAGAFCLALKIL 356
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 87.4 bits (215), Expect = 2e-17
Identities = 80/253 (31%), Positives = 107/253 (42%), Gaps = 18/253 (7%)
Query: 48 PCPLPGDSGICDLFESPSS-----GSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYG 102
P P P S L PSS G + S R P PG + ++ L LQ R+Y
Sbjct: 23 PRPSPLQSLAASLDAEPSSAAVPDGFPAGPTVSPRRLARP-PGLEEALSALGLQGEREYA 81
Query: 103 QSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLD 162
+A + P AL R VT E R ++ WL+ VH GL+ ++L L V+ LD
Sbjct: 82 GDIFA--EVMVCRVLPLRALPRA--VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLD 137
Query: 163 RFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLH 222
+L+ V QLLGV L +ACK E P L L +FSR +L E +L
Sbjct: 138 SYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILS 197
Query: 223 KLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSL 282
+L F L P L A A + + LA ELSL + + P
Sbjct: 198 RLDFRLHHPGPLLCLGLLA--------ALAGSSPQVMLLATYFLELSLLEAEAAGWEPGR 249
Query: 283 LAICCLALADRML 295
A L+LA R+L
Sbjct: 250 RAAAALSLAHRLL 262
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 85.9 bits (211), Expect = 5e-17
Identities = 51/191 (26%), Positives = 91/191 (47%), Gaps = 8/191 (4%)
Query: 101 YGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNT 160
Y + +++ K +E F + + RQ ++T++ R L+ WL+ V F ++ E+L L V
Sbjct: 1129 YAKEIFSYMKEREEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKL 1188
Query: 161 LDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIV 220
+D +L D QLLG T+ +IA K E + PRV + +C + R ++ ++E +
Sbjct: 1189 VDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINI 1248
Query: 221 LHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSP 280
L+ L + P FL + ++ L+R + E++L +Y +
Sbjct: 1249 LNVLKCDINIPIAYHFLRRYARC--------IHTNMKTLTLSRYICEMTLQEYHYVQEKA 1300
Query: 281 SLLAICCLALA 291
S LA L LA
Sbjct: 1301 SKLAAASLLLA 1311
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 69.3 bits (168), Expect = 5e-12
Identities = 50/176 (28%), Positives = 79/176 (44%), Gaps = 4/176 (2%)
Query: 125 QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLL 184
Q +V R + +W++ V + E L +N LDRFL+ PV QLLG T +
Sbjct: 49 QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108
Query: 185 IACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHAR 244
+A K E P ++L + ++L +E ++++KL + L A T F+EHF
Sbjct: 109 VASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKM 168
Query: 245 VEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP 300
EA + + AQ L D F S PS++A + A + L + P
Sbjct: 169 PEAEENKQIIRKHAQTF----VALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSP 220
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 65.1 bits (157), Expect = 9e-11
Identities = 54/178 (30%), Positives = 79/178 (44%), Gaps = 14/178 (7%)
Query: 113 ESHFHPREALAR--QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPV 170
E + PR + + Q ++ R L W++ V + E L +N LDR+L+ P
Sbjct: 35 EERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPT 94
Query: 171 AADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGA 230
QLLG +L+A K E P +++L A S +QL + E +VL KL + L A
Sbjct: 95 RKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAA 154
Query: 231 PTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLA----DYAFTSYSPSLLA 284
FL H S + QAL + A+ LA DY F Y PS++A
Sbjct: 155 VIAHDFLAFILH--------RLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 63.2 bits (152), Expect = 3e-10
Identities = 47/189 (24%), Positives = 84/189 (44%), Gaps = 19/189 (10%)
Query: 58 CDLFESPSSGSDGAESPS--------AARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFR 109
C L +P D P+ A GSPLP + ++ + +
Sbjct: 72 CSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLP----------VLSWANREEVWKIML 121
Query: 110 KAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTP 169
++++ + L + P + + R LL WL+ V + L E+ L + DR++ T
Sbjct: 122 NKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQE 181
Query: 170 -VAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTL 228
V QL+G++SL IA K E++PP++ Q + GA S ++ +E +++ L + L
Sbjct: 182 NVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRL 241
Query: 229 GAPTISFFL 237
TI +L
Sbjct: 242 SPLTIVSWL 250
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 63.2 bits (152), Expect = 3e-10
Identities = 47/189 (24%), Positives = 84/189 (44%), Gaps = 19/189 (10%)
Query: 58 CDLFESPSSGSDGAESPS--------AARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFR 109
C L +P D P+ A GSPLP + ++ + +
Sbjct: 57 CSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLP----------VLSWANREEVWKIML 106
Query: 110 KAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTP 169
++++ + L + P + + R LL WL+ V + L E+ L + DR++ T
Sbjct: 107 NKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQE 166
Query: 170 -VAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTL 228
V QL+G++SL IA K E++PP++ Q + GA S ++ +E +++ L + L
Sbjct: 167 NVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRL 226
Query: 229 GAPTISFFL 237
TI +L
Sbjct: 227 SPLTIVSWL 235
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 62.0 bits (149), Expect = 8e-10
Identities = 39/132 (29%), Positives = 65/132 (49%), Gaps = 1/132 (0%)
Query: 110 KAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRF-LTTT 168
K + + H + + + R LL WL+ V + L E+ L + DRF LT
Sbjct: 119 KKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQK 178
Query: 169 PVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTL 228
+ + QL+G+TSL IA K E++ P++++ + GA S + + +E I+L L + L
Sbjct: 179 DINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 238
Query: 229 GAPTISFFLEHF 240
TI +L F
Sbjct: 239 CPVTIISWLNLF 250
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 125 QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLL 184
Q + R + +W++ V + E L +N LDRFL P QLLG +
Sbjct: 48 QKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMF 107
Query: 185 IACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHAR 244
+A K E P ++L + Q+L E +VL KL + L A T F+EH R
Sbjct: 108 LASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHI--LR 165
Query: 245 VEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLA 284
Q E + A+ L D+ F Y PS++A
Sbjct: 166 KLPQQREKLSLIRKH--AQTFIALCATDFKFAMYPPSMIA 203
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 15/178 (8%)
Query: 143 VHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEVHPPRVKQL 200
V +F L + L V LD F+ ++ L+ ++ LL+A K + E P+++QL
Sbjct: 50 VSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQL 109
Query: 201 LALCCGA-----FSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAE---- 251
+L C ++Q L ++E ++L + L PT + F+E++ V
Sbjct: 110 NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWP 169
Query: 252 ----ASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRL 305
L A E+SL DYAF +Y+PSL+A C+A + +LR+S RL
Sbjct: 170 MICLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRL 227
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 60.5 bits (145), Expect = 2e-09
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 8/145 (5%)
Query: 147 FGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCG 206
F ++ E+L L V +D +L D QLLG T+ +IA K E + PRV + +C
Sbjct: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
Query: 207 AFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVA 266
+ R ++ ++E +L+ L + P FL + ++ L+R +
Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARC--------IHTNMKTLTLSRYIC 182
Query: 267 ELSLADYAFTSYSPSLLAICCLALA 291
E++L +Y + S LA L LA
Sbjct: 183 EMTLQEYHYVQEKASKLAAASLLLA 207
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 58.5 bits (140), Expect = 8e-09
Identities = 57/197 (28%), Positives = 82/197 (41%), Gaps = 16/197 (8%)
Query: 112 QESHFHPREALARQPQVTAES--------RCKLLSWLIPVHRQFGLSFESLCLTVNTLDR 163
QE F PRE + T E+ R + L + FG E+ L VN LDR
Sbjct: 27 QEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDR 86
Query: 164 FLTTTPVAADCFQLLGVTSLLIACKQVE--VHPPRVKQLLALCCGAFSRQQLCNLECIVL 221
FL V +GV S L+A + VE + P ++ + + + +E I+
Sbjct: 87 FLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIIS 146
Query: 222 HKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD--YAFTSYS 279
KLH+ L A T FL H H + +E E L L A+L + F+
Sbjct: 147 EKLHYELEATTALNFL-HLYHTIILCHTSERKEILSLDKLE---AQLKACNCRLIFSKAK 202
Query: 280 PSLLAICCLALADRMLR 296
PS+LA+C L L L+
Sbjct: 203 PSVLALCLLNLEVETLK 219
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/131 (33%), Positives = 61/131 (46%), Gaps = 12/131 (9%)
Query: 158 VNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLE 217
+N LDR+L+ P QLLG +L+A K E P +++L A S +QL + E
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
Query: 218 CIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLA----DY 273
+VL KL + L A FL H S + QAL + A+ LA DY
Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILH--------RLSLPRDRQALVKKHAQTFLALCATDY 112
Query: 274 AFTSYSPSLLA 284
F Y PS++A
Sbjct: 113 TFAMYPPSMIA 123
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 50.1 bits (118), Expect = 3e-06
Identities = 56/227 (24%), Positives = 94/227 (41%), Gaps = 16/227 (7%)
Query: 92 QLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSF 151
QL L+ C F+ +Q ++ + Q + R L+ WL+ V F
Sbjct: 271 QLGLEVRASSEIVCQLFQASQA--VSKQQVFSVQKGLNDTMRYILIDWLVEVATM--KDF 326
Query: 152 ESLCL--TVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFS 209
SLCL TV +DR+L V QLLG+ ++I + + +++ + L +
Sbjct: 327 TSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYK 386
Query: 210 RQQLCNLECIVLHKLHFTLGAPTISFFLE-HFTHARVEAGQAEASEALEAQALARGVAEL 268
+ L + ++ L + PT+ + E T VE L Q L + EL
Sbjct: 387 YEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVE---------LRTQHLCSFLCEL 437
Query: 269 SLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALED 315
SL + ++Y+P+ LA L LA ++P +L D + ED
Sbjct: 438 SLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYED 484
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 109 RKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTT 168
R+AQ + R+ + Q V+ R +++ WL + QF L E+ L + LDRFL T
Sbjct: 22 REAQMWKVNVRKMPSNQ-NVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
Query: 169 PVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAF---SRQQLCNLECIVLHKLH 225
+ ++ +A K VE R+ L L +F S ++ +E I+L KL+
Sbjct: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
Query: 226 FTLGAPTISFFLEHFTHA 243
+ L T FL H HA
Sbjct: 140 WDLHTATPLDFL-HIFHA 156
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 47.8 bits (112), Expect = 1e-05
Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 127 QVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIA 186
++TA R + L+ + + FG E+ L VN LDRFL+ V +G++ +A
Sbjct: 46 RMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLA 105
Query: 187 CKQVEV--HPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF---- 240
K +E + P L+ + F+ L +E IVL K+ + + A T FL+ +
Sbjct: 106 VKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLL 165
Query: 241 -THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLAL 290
+ +E + E LEAQ A F+ PS+LA+ +AL
Sbjct: 166 QENLPLERRNSINFERLEAQLKA------CHCRIIFSKAKPSVLALSIIAL 210
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 47.8 bits (112), Expect = 1e-05
Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 127 QVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIA 186
++TA R + L+ + + FG E+ L VN LDRFL+ V +G++ +A
Sbjct: 46 RMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLA 105
Query: 187 CKQVEV--HPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF---- 240
K +E + P L+ + F+ L +E IVL K+ + + A T FL+ +
Sbjct: 106 VKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLL 165
Query: 241 -THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLAL 290
+ +E + E LEAQ A F+ PS+LA+ +AL
Sbjct: 166 QENLPLERRNSINFERLEAQLKA------CHCRIIFSKAKPSVLALSIIAL 210
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 11/170 (6%)
Query: 143 VHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEVHPPRVKQL 200
V +F L + L V LD F+ ++ L+ ++ LL+A K + E P+++QL
Sbjct: 50 VSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQL 109
Query: 201 LALCCGA-----FSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEA 255
+L C ++Q L ++E ++L + L PT + F+E++ V + + +
Sbjct: 110 NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVH--ETDLHDG 167
Query: 256 LEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRL 305
L + +L +A YA SL A C+A + +LR+S RL
Sbjct: 168 WPMICLEK--TKLYMAKYADYFLEVSLQAAACVASSRIILRLSPTWPTRL 215
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 12/171 (7%)
Query: 143 VHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEVHPPRVKQL 200
V +F L + L V LD F+ ++ L+ ++ LL+A K + E P+++QL
Sbjct: 50 VSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQL 109
Query: 201 LALCCGA-----FSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEA 255
+L C ++Q L ++E ++L + L PT + F+E++ V + + +
Sbjct: 110 NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVH--ETDLHDG 167
Query: 256 LEAQALARGVAELSLADYAFTSYSPSL-LAICCLALADRMLRVSRPVDLRL 305
L + +L +A YA SL +A C+A + +LR+S RL
Sbjct: 168 WPMICLEK--TKLYMAKYADYFLEVSLQVAAACVASSRIILRLSPTWPTRL 216
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 9/164 (5%)
Query: 135 KLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEV 192
+++ WL+ + F S + L + R L + V +TSL +A K + E
Sbjct: 152 EVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEE 211
Query: 193 HPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEA 252
P+VK +S +L +E +L +LH+ L T FL F HA V
Sbjct: 212 FIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIF-HALVVLSWPHV 270
Query: 253 SEALEAQALARGVAELS------LADYAFTSYSPSLLAICCLAL 290
E L + + VA L+ +A + + S LA+ + L
Sbjct: 271 LELLPQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITL 314
>gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo sapiens]
Length = 441
Score = 35.4 bits (80), Expect = 0.077
Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 11 SPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDG 70
+P R+ R D+ AP+ PRLR +QP P P P D C + DG
Sbjct: 31 APPRRSADRREDEKAEAPLAGD--PRLRGRQPGAPGGPQPPGSDRNQC------PAKPDG 82
Query: 71 AESPSAARGGSPLP-GPAQP 89
+P+ R G GPA P
Sbjct: 83 GGAPNGVRNGLAAELGPASP 102
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 35.4 bits (80), Expect = 0.077
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 8 SPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICD-------- 59
SP A G D+D + A +K RRP RR+ P P P P + + D
Sbjct: 130 SPPDSEAYYGETDSDADGPATQEKPRRP--RRRGPTRPTPPGAPPDEVYLSDSPAEPAPT 187
Query: 60 LFESPSSGSDGAESPSAARGGSPLPGPAQ 88
+ PS G SPS G + P PA+
Sbjct: 188 IPGPPSQGDSRVSSPSWEDGAALQPPPAE 216
>gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]
Length = 393
Score = 35.4 bits (80), Expect = 0.077
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 36 RLRRKQPLHPLNP---CPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQ 92
R R P HPL P P+ ++G D+ E SG +GAE G S PGPA
Sbjct: 274 RRRGGLPPHPLGPRRSSPVGAEAGPEDM-EDGDSGIEGAEGAGLEEGSSLGPGPAPDTDT 332
Query: 93 LDLQTFR 99
L L + R
Sbjct: 333 LSLLSLR 339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,357,601
Number of Sequences: 37866
Number of extensions: 800276
Number of successful extensions: 3802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 3644
Number of HSP's gapped (non-prelim): 274
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.