BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|153070262 meprin A alpha [Homo sapiens] (746 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|153070262 meprin A alpha [Homo sapiens] 1546 0.0 gi|153070264 meprin A beta [Homo sapiens] 514 e-145 gi|157502169 astacin-like metalloendopeptidase [Homo sapiens] 122 9e-28 gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 105 2e-22 gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 105 2e-22 gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 105 2e-22 gi|6912724 tolloid-like 2 [Homo sapiens] 104 3e-22 gi|22547221 tolloid-like 1 [Homo sapiens] 103 4e-22 gi|24111244 MAM domain containing glycosylphosphatidylinositol a... 64 7e-10 gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens] 59 2e-08 gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens] 59 2e-08 gi|223942069 enterokinase precursor [Homo sapiens] 59 2e-08 gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho... 55 2e-07 gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho... 55 2e-07 gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho... 55 2e-07 gi|22027622 TNF receptor-associated factor 4 [Homo sapiens] 52 2e-06 gi|223278413 MAM domain containing 2 [Homo sapiens] 52 3e-06 gi|24041035 notch 2 preproprotein [Homo sapiens] 48 4e-05 gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] 48 4e-05 gi|22027630 TNF receptor-associated factor 6 [Homo sapiens] 47 5e-05 gi|4759254 TNF receptor-associated factor 6 [Homo sapiens] 47 5e-05 gi|182508169 neuropilin 1 isoform a [Homo sapiens] 47 6e-05 gi|119220585 apical early endosomal glycoprotein precursor [Homo... 46 1e-04 gi|13124888 epidermal growth factor-like protein 6 precursor [Ho... 45 2e-04 gi|74136023 delta-like 1 homolog [Homo sapiens] 44 7e-04 gi|22027612 TNF receptor-associated factor 2 [Homo sapiens] 44 7e-04 gi|148886654 polydom [Homo sapiens] 44 7e-04 gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ... 43 0.001 gi|75709198 nephronectin [Homo sapiens] 42 0.002 gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens] 41 0.005 >gi|153070262 meprin A alpha [Homo sapiens] Length = 746 Score = 1546 bits (4002), Expect = 0.0 Identities = 746/746 (100%), Positives = 746/746 (100%) Query: 1 MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDIL 60 MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDIL Sbjct: 1 MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDIL 60 Query: 61 LQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYI 120 LQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYI Sbjct: 61 LQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYI 120 Query: 121 IFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW 180 IFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW Sbjct: 121 IFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW 180 Query: 181 DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIG 240 DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIG Sbjct: 181 DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIG 240 Query: 241 QRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV 300 QRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV Sbjct: 241 QRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV 300 Query: 301 DHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVV 360 DHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVV Sbjct: 301 DHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVV 360 Query: 361 WVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIY 420 WVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIY Sbjct: 361 WVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIY 420 Query: 421 LDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSG 480 LDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSG Sbjct: 421 LDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSG 480 Query: 481 YLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAIND 540 YLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAIND Sbjct: 481 YLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAIND 540 Query: 541 TVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLS 600 TVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLS Sbjct: 541 TVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLS 600 Query: 601 QTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGP 660 QTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGP Sbjct: 601 QTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGP 660 Query: 661 LEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLG 720 LEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLG Sbjct: 661 LEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLG 720 Query: 721 MVIGGTAGVIFLTFSIIAILSQRPRK 746 MVIGGTAGVIFLTFSIIAILSQRPRK Sbjct: 721 MVIGGTAGVIFLTFSIIAILSQRPRK 746 >gi|153070264 meprin A beta [Homo sapiens] Length = 701 Score = 514 bits (1324), Expect = e-145 Identities = 266/578 (46%), Positives = 367/578 (63%), Gaps = 16/578 (2%) Query: 34 DADFGEQKDISEINLAAGLDLFQGDILLQKS--RNGLRDPNTRWTFPIPYILADNLGLNA 91 D D G +DI +IN GLDLF+GDI L ++ RN + RW IPY+L D+L +NA Sbjct: 28 DVDGGMDQDIFDINEGLGLDLFEGDIRLDRAQIRNSIIGEKYRWPHTIPYVLEDSLEMNA 87 Query: 92 KGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVG-QNISIGQGCAYK 150 KG IL AFE +RLK+C+DFKP+ GE++YI + GCWS VG++ VG Q +SIG C Sbjct: 88 KGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRI 147 Query: 151 AIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYES 210 A ++HE LHALGF+HEQSR+DRDDYV I WD+ILSG +HNF+TY D + LN PYDY S Sbjct: 148 ATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTS 207 Query: 211 LMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCT 270 +MHY +F +N + PTI +I +F +IGQR+DFS DL +LN++YNC+++ + +D C+ Sbjct: 208 VMHYSKTAF-QNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCS 266 Query: 271 FEKANICGMIQGTRDDTDWAHQDSAQAG-EVDHTLLGQCTGAGYFMQFSTSSGSAEEAAL 329 FE N+CGMIQ + D+ DW G E DH+ +GQC G+G+FM F +SS + A+ Sbjct: 267 FELENVCGMIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAV 326 Query: 330 LESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWK 389 LESR LYPKR QCLQF+ +GS SD+L +++R + L V+ + +W+ Sbjct: 327 LESRTLYPKRGFQCLQFYLYNSGSESDQLNIYIREYSADNVDGNLTLVEEIKEIPTGSWQ 386 Query: 390 IAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTS 449 + HV LK +KFR +F+G KG S GG+ +DDI L+ET CP +W +RNF+Q + S Sbjct: 387 LYHVTLKVTKKFRVVFEGRKGSGA-SLGGLSIDDINLSETRCPHHIWHIRNFTQFI--GS 443 Query: 450 KGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIIT 509 L SP FY+S+GY F + L ++G + FH+ SG ND L+WP +Q +T Sbjct: 444 PNGTLYSPPFYSSKGYAFQIYLNLAHVTNAG---IYFHLISGANDDQLQWPCPWQQATMT 500 Query: 510 ILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGT---YHTDCNCFRSIDLG 566 +LDQ PD+R RMS+ TT T+ N WDRPS+VGT + R G Sbjct: 501 LLDQNPDIRQRMSNQRSITTDPFMTTD--NGNYFWDRPSKVGTVALFSNGTQFRRGGGYG 558 Query: 567 WSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEV 604 S FI+H+ LK R F+K DD+ I + EDI+HL+ T++ Sbjct: 559 TSAFITHERLKSRDFIKGDDVYILLTVEDISHLNSTQI 596 >gi|157502169 astacin-like metalloendopeptidase [Homo sapiens] Length = 431 Score = 122 bits (307), Expect = 9e-28 Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 22/236 (9%) Query: 41 KDISEINLAAGLD-------LFQGDILLQKSRNGLRDPNTRWTF------PIPYILADNL 87 KDI IN L+ L +GDI+ L + +W +P++L+ Sbjct: 53 KDIPAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKY 112 Query: 88 GLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGC 147 ++ IL A F +C+ F Y+ + +I GC+S VG Q +S+ C Sbjct: 113 DEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTC 172 Query: 148 AYKA--IIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTP 205 K I+ HE++H LGF+HE +R DRD Y+ + W++IL G++ NF S ++ TP Sbjct: 173 LQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSS---NMLTP 229 Query: 206 YDYESLMHYQPFSFNKNASVPTITAK-IPEFNSIIGQRLDFSAIDLERLNRMYNCT 260 YDY S+MHY +F++ +PTIT P + IGQR + SA D+ R+ ++Y C+ Sbjct: 230 YDYSSVMHYGRLAFSRR-GLPTITPLWAPSVH--IGQRWNLSASDITRVLKLYGCS 282 >gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens] Length = 730 Score = 105 bits (262), Expect = 2e-22 Identities = 65/197 (32%), Positives = 99/197 (50%), Gaps = 6/197 (3%) Query: 79 IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137 IP+++ N + + A + +CV F E SYI+F GC S VG + Sbjct: 135 IPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGG 194 Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196 G Q ISIG+ C I+ HE+ H +GF+HE +R DRD +V+I + I G ++NF + Sbjct: 195 GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEP 254 Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSI---IGQRLDFSAIDLERL 253 + L YD++S+MHY +F++ + TI K E N + IGQR S D+ + Sbjct: 255 QEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKY-EVNGVKPPIGQRTRLSKGDIAQA 313 Query: 254 NRMYNCTTTHTLLDHCT 270 ++Y C L T Sbjct: 314 RKLYKCPACGETLQDST 330 >gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo sapiens] Length = 823 Score = 105 bits (262), Expect = 2e-22 Identities = 65/197 (32%), Positives = 99/197 (50%), Gaps = 6/197 (3%) Query: 79 IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137 IP+++ N + + A + +CV F E SYI+F GC S VG + Sbjct: 135 IPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGG 194 Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196 G Q ISIG+ C I+ HE+ H +GF+HE +R DRD +V+I + I G ++NF + Sbjct: 195 GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEP 254 Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSI---IGQRLDFSAIDLERL 253 + L YD++S+MHY +F++ + TI K E N + IGQR S D+ + Sbjct: 255 QEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKY-EVNGVKPPIGQRTRLSKGDIAQA 313 Query: 254 NRMYNCTTTHTLLDHCT 270 ++Y C L T Sbjct: 314 RKLYKCPACGETLQDST 330 >gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo sapiens] Length = 986 Score = 105 bits (262), Expect = 2e-22 Identities = 65/197 (32%), Positives = 99/197 (50%), Gaps = 6/197 (3%) Query: 79 IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137 IP+++ N + + A + +CV F E SYI+F GC S VG + Sbjct: 135 IPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGG 194 Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196 G Q ISIG+ C I+ HE+ H +GF+HE +R DRD +V+I + I G ++NF + Sbjct: 195 GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEP 254 Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSI---IGQRLDFSAIDLERL 253 + L YD++S+MHY +F++ + TI K E N + IGQR S D+ + Sbjct: 255 QEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKY-EVNGVKPPIGQRTRLSKGDIAQA 313 Query: 254 NRMYNCTTTHTLLDHCT 270 ++Y C L T Sbjct: 314 RKLYKCPACGETLQDST 330 >gi|6912724 tolloid-like 2 [Homo sapiens] Length = 1015 Score = 104 bits (260), Expect = 3e-22 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 4/196 (2%) Query: 79 IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQ-QFDGCWSEVGDQHV 137 IPY++ N + + A + +CV F E S+I+F + GC S VG + Sbjct: 164 IPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGG 223 Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196 G Q ISIG+ C I+ HE+ H +GF+HE +R DRD +V I + I G ++NF + Sbjct: 224 GPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEA 283 Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPE--FNSIIGQRLDFSAIDLERLN 254 ++ L YD++S+MHY +F++ + TI + + IGQR+ S D+ + Sbjct: 284 GEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQAR 343 Query: 255 RMYNCTTTHTLLDHCT 270 ++Y C L T Sbjct: 344 KLYKCPACGETLQDTT 359 >gi|22547221 tolloid-like 1 [Homo sapiens] Length = 1013 Score = 103 bits (258), Expect = 4e-22 Identities = 61/185 (32%), Positives = 94/185 (50%), Gaps = 4/185 (2%) Query: 79 IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137 IPY++ N + + A + +CV F E SYI+F GC S VG + Sbjct: 162 IPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEESYIVFTYRPCGCCSYVGRRGN 221 Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196 G Q ISIG+ C I+ HE+ H +GF+HE +R DRD++V I + I G ++NF + Sbjct: 222 GPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEP 281 Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPE--FNSIIGQRLDFSAIDLERLN 254 + L YD++S+MHY +F++ + TI + IGQR S D+ + Sbjct: 282 GEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQAR 341 Query: 255 RMYNC 259 ++Y C Sbjct: 342 KLYRC 346 >gi|24111244 MAM domain containing glycosylphosphatidylinositol anchor 1 [Homo sapiens] Length = 955 Score = 63.5 bits (153), Expect = 7e-10 Identities = 49/170 (28%), Positives = 69/170 (40%), Gaps = 11/170 (6%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLG-----QCTGAGYFMQFSTS-SG 322 C FE ICG Q D+ DW Q++ G T GY+M TS Sbjct: 753 CHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPR 812 Query: 323 SAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQG 382 + A L S + K C+ FFY M G L + VR S + G Sbjct: 813 ELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVR---SRNKGALDTHAWSLSG 869 Query: 383 DDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCP 432 + + W+ AHV + F+ +F+G +G G I +DD+TL + CP Sbjct: 870 NKGNVWQQAHVPISPSGPFQIIFEGVRG--PGYLGDIAIDDVTLKKGECP 917 >gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens] Length = 956 Score = 58.9 bits (141), Expect = 2e-08 Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 19/178 (10%) Query: 268 HCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLG-----QCTGAGYFMQFSTSSG 322 HC FE NIC Q D+ DW Q +A G + G++M TS Sbjct: 747 HCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRP 806 Query: 323 SAE-EAALLESRILY--------PKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRK 373 E E A L S + P C FFY M G L V++R T Sbjct: 807 RLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENP 866 Query: 374 LVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 L + G+ W AHV + F+ +F+G +G G I +DD+++ E C Sbjct: 867 L---WSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRG--PGIEGDIAIDDVSIAEGEC 919 >gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens] Length = 727 Score = 58.9 bits (141), Expect = 2e-08 Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 19/178 (10%) Query: 268 HCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLG-----QCTGAGYFMQFSTSSG 322 HC FE NIC Q D+ DW Q +A G + G++M TS Sbjct: 518 HCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRP 577 Query: 323 SAE-EAALLESRILY--------PKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRK 373 E E A L S + P C FFY M G L V++R T Sbjct: 578 RLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENP 637 Query: 374 LVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 L + G+ W AHV + F+ +F+G +G G I +DD+++ E C Sbjct: 638 L---WSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRG--PGIEGDIAIDDVSIAEGEC 690 >gi|223942069 enterokinase precursor [Homo sapiens] Length = 1019 Score = 58.5 bits (140), Expect = 2e-08 Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 17/169 (10%) Query: 268 HCTFEKANICGMIQGTRDDTDWAHQDSAQAG-----EVDHTLLGQCTGAGYFMQFSTSSG 322 +C FE C +Q DD +W + DHT +G+++ T G Sbjct: 346 NCNFEDG-FCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTF---GNASGFYISTPTGPG 401 Query: 323 SAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQG 382 +E L S L P + CL F+Y M G +L + + D N+ K V + +G Sbjct: 402 GRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQ---NMEKTVFQK--EG 456 Query: 383 DDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 + NW V L E KF+ F K I LDDI+LT C Sbjct: 457 NYGDNWNYGQVTLNETVKFKVAFNAFK---NKILSDIALDDISLTYGIC 502 >gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo sapiens] Length = 1542 Score = 55.1 bits (131), Expect = 2e-07 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 13/165 (7%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324 C FE IC Q +DD DW + G + LG G +++ S Sbjct: 230 CNFE-TGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQ 288 Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVR-RDDSTGNVRKLVKVQTFQGD 383 + AALL + K +F+Y M G RL ++ R DS G + + G+ Sbjct: 289 DSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQL-----LWQIFGN 343 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428 + W H+ + Q F+ L + + GD TG I +DD++ + Sbjct: 344 QGNRWIRKHLNISSRQPFQILVEASVGD--GFTGDIAIDDLSFMD 386 Score = 43.5 bits (101), Expect = 7e-04 Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 34/255 (13%) Query: 265 LLDHCTFEKANICGMIQ---------------GTRDDTDWAHQDSAQAGEVDHTLLGQCT 309 +++ C+FEK ++C Q G + H + VDHT Q T Sbjct: 451 VMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT---QNT 507 Query: 310 GAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTG 369 G+++ +S+G + A + + I+ + L F+ M G+ L V +++D+ T Sbjct: 508 TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTS 567 Query: 370 NVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTET 429 K+ G WK A V L + +F+ +G + G + +DDI+ + Sbjct: 568 ------KLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRG--ISYIGDVAVDDISFQDC 619 Query: 430 P---CPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAF 486 P T F ++ DKL F N T + R SSG F Sbjct: 620 SPLLSPERKCTDHEFMCANKHCIAKDKLCD--FVNDCADNSDETTF-ICRTSSGRCDFEF 676 Query: 487 HVCS--GENDAILEW 499 +CS E D +W Sbjct: 677 DLCSWKQEKDEDFDW 691 Score = 42.7 bits (99), Expect = 0.001 Identities = 48/165 (29%), Positives = 73/165 (44%), Gaps = 15/165 (9%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSA--QAGE---VDHTLLGQCTGAGYFMQFSTSSGS 323 C FE ++C Q +D DW + S+ AG DHTL G +G F+ S Sbjct: 672 CDFE-FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTL-GNSSGHYIFIN-SLFPQQ 728 Query: 324 AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383 AA + S ++ + K + F Y M G+ L + + T + L+ + QG+ Sbjct: 729 PMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLM--QVSVTNQTKVLLNLTVEQGN 786 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428 W+ + L ++ F+ F+G G Q G I LDDI LTE Sbjct: 787 F---WRREELSLFGDEDFQLKFEGRVGKGQR--GDIALDDIVLTE 826 Score = 38.5 bits (88), Expect = 0.023 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 21/187 (11%) Query: 258 NCTTTHTLLDHCTFEKAN-----ICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQC 308 +C + C FE ++ C + Q + DD DWA A + DHT Sbjct: 1153 HCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHT----- 1207 Query: 309 TGAGYFMQFSTSSGSAE-EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDS 367 G+G + SSGS E A + + +P C F+ P ++ V + Sbjct: 1208 PGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEE 1267 Query: 368 TGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLT 427 +G + V + G+ W V L F+ F+ N I LDDI+ T Sbjct: 1268 SG---LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDG--NEDIFIALDDISFT 1322 Query: 428 ETPCPTG 434 C TG Sbjct: 1323 -PECVTG 1328 >gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo sapiens] Length = 1817 Score = 55.1 bits (131), Expect = 2e-07 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 13/165 (7%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324 C FE IC Q +DD DW + G + LG G +++ S Sbjct: 505 CNFE-TGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQ 563 Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVR-RDDSTGNVRKLVKVQTFQGD 383 + AALL + K +F+Y M G RL ++ R DS G + + G+ Sbjct: 564 DSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQL-----LWQIFGN 618 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428 + W H+ + Q F+ L + + GD TG I +DD++ + Sbjct: 619 QGNRWIRKHLNISSRQPFQILVEASVGD--GFTGDIAIDDLSFMD 661 Score = 43.5 bits (101), Expect = 7e-04 Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 34/255 (13%) Query: 265 LLDHCTFEKANICGMIQ---------------GTRDDTDWAHQDSAQAGEVDHTLLGQCT 309 +++ C+FEK ++C Q G + H + VDHT Q T Sbjct: 726 VMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT---QNT 782 Query: 310 GAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTG 369 G+++ +S+G + A + + I+ + L F+ M G+ L V +++D+ T Sbjct: 783 TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTS 842 Query: 370 NVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTET 429 K+ G WK A V L + +F+ +G + G + +DDI+ + Sbjct: 843 ------KLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRG--ISYIGDVAVDDISFQDC 894 Query: 430 P---CPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAF 486 P T F ++ DKL F N T + R SSG F Sbjct: 895 SPLLSPERKCTDHEFMCANKHCIAKDKLCD--FVNDCADNSDETTF-ICRTSSGRCDFEF 951 Query: 487 HVCS--GENDAILEW 499 +CS E D +W Sbjct: 952 DLCSWKQEKDEDFDW 966 Score = 43.1 bits (100), Expect = 0.001 Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 15/165 (9%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSA--QAGE---VDHTLLGQCTGAGYFMQFSTSSGS 323 C FE ++C Q +D DW + S+ AG DHTL G +G F++ S Sbjct: 947 CDFE-FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTL-GNSSGHYIFIK-SLFPQQ 1003 Query: 324 AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383 AA + S ++ + K + F Y M G+ L + + T + L+ + QG+ Sbjct: 1004 PMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLM--QVSVTNQTKVLLNLTVEQGN 1061 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428 W+ + L ++ F+ F+G G Q G I LDDI LTE Sbjct: 1062 F---WRREELSLFGDEDFQLKFEGRVGKGQR--GDIALDDIVLTE 1101 Score = 38.5 bits (88), Expect = 0.023 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 21/187 (11%) Query: 258 NCTTTHTLLDHCTFEKAN-----ICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQC 308 +C + C FE ++ C + Q + DD DWA A + DHT Sbjct: 1428 HCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHT----- 1482 Query: 309 TGAGYFMQFSTSSGSAE-EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDS 367 G+G + SSGS E A + + +P C F+ P ++ V + Sbjct: 1483 PGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEE 1542 Query: 368 TGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLT 427 +G + V + G+ W V L F+ F+ N I LDDI+ T Sbjct: 1543 SG---LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDG--NEDIFIALDDISFT 1597 Query: 428 ETPCPTG 434 C TG Sbjct: 1598 -PECVTG 1603 >gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo sapiens] Length = 1817 Score = 55.1 bits (131), Expect = 2e-07 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 13/165 (7%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324 C FE IC Q +DD DW + G + LG G +++ S Sbjct: 505 CNFE-TGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQ 563 Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVR-RDDSTGNVRKLVKVQTFQGD 383 + AALL + K +F+Y M G RL ++ R DS G + + G+ Sbjct: 564 DSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQL-----LWQIFGN 618 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428 + W H+ + Q F+ L + + GD TG I +DD++ + Sbjct: 619 QGNRWIRKHLNISSRQPFQILVEASVGD--GFTGDIAIDDLSFMD 661 Score = 43.5 bits (101), Expect = 7e-04 Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 34/255 (13%) Query: 265 LLDHCTFEKANICGMIQ---------------GTRDDTDWAHQDSAQAGEVDHTLLGQCT 309 +++ C+FEK ++C Q G + H + VDHT Q T Sbjct: 726 VMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT---QNT 782 Query: 310 GAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTG 369 G+++ +S+G + A + + I+ + L F+ M G+ L V +++D+ T Sbjct: 783 TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTS 842 Query: 370 NVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTET 429 K+ G WK A V L + +F+ +G + G + +DDI+ + Sbjct: 843 ------KLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRG--ISYIGDVAVDDISFQDC 894 Query: 430 P---CPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAF 486 P T F ++ DKL F N T + R SSG F Sbjct: 895 SPLLSPERKCTDHEFMCANKHCIAKDKLCD--FVNDCADNSDETTF-ICRTSSGRCDFEF 951 Query: 487 HVCS--GENDAILEW 499 +CS E D +W Sbjct: 952 DLCSWKQEKDEDFDW 966 Score = 43.1 bits (100), Expect = 0.001 Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 15/165 (9%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSA--QAGE---VDHTLLGQCTGAGYFMQFSTSSGS 323 C FE ++C Q +D DW + S+ AG DHTL G +G F++ S Sbjct: 947 CDFE-FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTL-GNSSGHYIFIK-SLFPQQ 1003 Query: 324 AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383 AA + S ++ + K + F Y M G+ L + + T + L+ + QG+ Sbjct: 1004 PMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLM--QVSVTNQTKVLLNLTVEQGN 1061 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428 W+ + L ++ F+ F+G G Q G I LDDI LTE Sbjct: 1062 F---WRREELSLFGDEDFQLKFEGRVGKGQR--GDIALDDIVLTE 1101 Score = 38.5 bits (88), Expect = 0.023 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 21/187 (11%) Query: 258 NCTTTHTLLDHCTFEKAN-----ICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQC 308 +C + C FE ++ C + Q + DD DWA A + DHT Sbjct: 1428 HCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHT----- 1482 Query: 309 TGAGYFMQFSTSSGSAE-EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDS 367 G+G + SSGS E A + + +P C F+ P ++ V + Sbjct: 1483 PGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEE 1542 Query: 368 TGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLT 427 +G + V + G+ W V L F+ F+ N I LDDI+ T Sbjct: 1543 SG---LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDG--NEDIFIALDDISFT 1597 Query: 428 ETPCPTG 434 C TG Sbjct: 1598 -PECVTG 1603 >gi|22027622 TNF receptor-associated factor 4 [Homo sapiens] Length = 470 Score = 52.4 bits (124), Expect = 2e-06 Identities = 41/161 (25%), Positives = 74/161 (45%), Gaps = 19/161 (11%) Query: 435 VWTVRNFSQVLENTSKGDKLQ--SPRFYNSE-GYGFGVTLYPNSRESSG--YLRLAFHVC 489 +W + ++ + L+ L+ SP FY + GY V+ + N S +L L V Sbjct: 311 IWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVL 370 Query: 490 SGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPS 548 G D +LEWP R+V ++LDQ +P + H + + W Sbjct: 371 PGAFDNLLEWPFA-RRVTFSLLDQSDPGL-----------AKPQHVTETFHPDPNWKNFQ 418 Query: 549 RVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589 + GT+ + S+ G+ FISHQ +++R+++++D + I Sbjct: 419 KPGTWRGSLD-ESSLGFGYPKFISHQDIRKRNYVRDDAVFI 458 >gi|223278413 MAM domain containing 2 [Homo sapiens] Length = 686 Score = 51.6 bits (122), Expect = 3e-06 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 17/168 (10%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQ-----DSAQAGEVDHTLLGQCTGAGYFMQFSTSSGS 323 CTFE+ C Q R+ + W + S + DHT TG GY+M S Sbjct: 509 CTFEQDE-CTFTQEKRNRSSWHRRRGETPTSYTGPKGDHT-----TGVGYYMYIEASHMV 562 Query: 324 AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383 + A L SR L + CL FFY M G + L V++++++ + + + +G+ Sbjct: 563 YGQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDS----EESLLWRRRGE 618 Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 +W A + E++ + +F+ +G S I +DD+ PC Sbjct: 619 QSISWLRALIEYSCERQHQIIFEAIRGVSIRS--DIAIDDVKFQAGPC 664 Score = 30.0 bits (66), Expect = 8.2 Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 25/173 (14%) Query: 269 CTFEKANICGMIQGTRDDTDW-----AHQDSAQAGEVDHTLLGQCTGAGYFMQF-STSSG 322 C FE+ ++CG + + +W + ++ DHT + G++M S Sbjct: 170 CDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSE---LGHYMYVDSVYVK 226 Query: 323 SAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQG 382 +E A L S L CL F+Y++ + ++ R D G ++ K Sbjct: 227 HFQEVAQLISP-LTTAPMAGCLSFYYQIQQGNDNVFSLYTR--DVAGLYEEIWKADR--- 280 Query: 383 DDDHNWKIAHVVLKE----EQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 + W +A V E F F G KG G + LDDI+ + C Sbjct: 281 PGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKG------GYVALDDISFSPVHC 327 >gi|24041035 notch 2 preproprotein [Homo sapiens] Length = 2471 Score = 47.8 bits (112), Expect = 4e-05 Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 6/47 (12%) Query: 671 RDPCDPNPCQNDGICV--NVKGMASCRCISGHAFFYTGERCQAVQVH 715 RDPC+ N CQN G CV + G A+CRC SG +TGE CQ H Sbjct: 65 RDPCEKNRCQNGGTCVAQAMLGKATCRCASG----FTGEDCQYSTSH 107 Score = 40.0 bits (92), Expect = 0.008 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 4/39 (10%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C NPCQN G C++ SC C+ G +TG++CQ Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPG----FTGDKCQ 947 Score = 38.5 bits (88), Expect = 0.023 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 5/54 (9%) Query: 674 CD-PNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGT 726 CD P CQ+ G C+N+ G C+C G +TG+ C ++ V + V GGT Sbjct: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQG----FTGQYCDSLYVPCAPSPCVNGGT 235 Score = 37.7 bits (86), Expect = 0.039 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C +PC N C V SC+C++G +TG++C+ Sbjct: 146 DACLSHPCANGSTCTTVANQFSCKCLTG----FTGQKCE 180 Score = 37.4 bits (85), Expect = 0.051 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 4/34 (11%) Query: 677 NPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 NPC++ G CVN G C C+ G Y G RC+ Sbjct: 425 NPCEHAGKCVNTDGAFHCECLKG----YAGPRCE 454 Score = 37.0 bits (84), Expect = 0.067 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAV 712 C +PC N+G CV+ G C C G YTG+ CQ + Sbjct: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLG----YTGKNCQTL 1063 Score = 35.4 bits (80), Expect = 0.19 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 4/41 (9%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAV 712 D C NPC N G C + +C C+ YTG+ CQ V Sbjct: 797 DECASNPCLNQGTCFDDISGYTCHCV----LPYTGKNCQTV 833 Score = 34.7 bits (78), Expect = 0.33 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 6/40 (15%) Query: 672 DPC--DPNPCQNDGICVNVKGMASCRCISGHAFFYTGERC 709 D C PN CQN G C N G C C++G ++G+ C Sbjct: 300 DECLLQPNACQNGGTCANRNGGYGCVCVNG----WSGDDC 335 Score = 34.3 bits (77), Expect = 0.43 Identities = 14/31 (45%), Positives = 17/31 (54%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFY 704 C +PC+N G CV K + C C SG A Y Sbjct: 1067 CSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097 Score = 33.9 bits (76), Expect = 0.57 Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 6/39 (15%) Query: 673 PCDPNPCQNDGICVNVKGMAS--CRCISGHAFFYTGERC 709 PC PNPC+N +C S C C G + G+RC Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAPG----WQGQRC 870 Score = 33.9 bits (76), Expect = 0.57 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 4/39 (10%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C PC N G+C N +G C C G ++G C+ Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPG----FSGMDCE 909 Score = 33.5 bits (75), Expect = 0.74 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Query: 672 DPCDPNP-CQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C P C N G C++ G SCRC+ G + GERC+ Sbjct: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPG----FAGERCE 1262 Score = 32.7 bits (73), Expect = 1.3 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 4/40 (10%) Query: 671 RDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 ++ C NPCQN G C N+ C C G + G CQ Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKG----FKGYNCQ 793 Score = 32.7 bits (73), Expect = 1.3 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 4/39 (10%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C NPCQ+ C + G C C+ G Y G C+ Sbjct: 1151 DECASNPCQHGATCSDFIGGYRCECVPG----YQGVNCE 1185 Score = 32.7 bits (73), Expect = 1.3 Identities = 12/32 (37%), Positives = 16/32 (50%) Query: 668 QYFRDPCDPNPCQNDGICVNVKGMASCRCISG 699 +Y D C PCQN G C+++ C C G Sbjct: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 1216 Score = 32.3 bits (72), Expect = 1.6 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 4/37 (10%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 C +PCQND C++ G +C C+ G + G C+ Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPG----FKGVHCE 492 Score = 32.3 bits (72), Expect = 1.6 Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 4/37 (10%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 C NPC N+G CV+ C C G +TG CQ Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPG----FTGPVCQ 530 Score = 32.0 bits (71), Expect = 2.1 Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 7/45 (15%) Query: 670 FRDPCDPNPCQNDGICVNVKGMAS---CRCISGHAFFYTGERCQA 711 F D C PC N G C M CRC G ++G RCQ+ Sbjct: 1304 FVDVCPQMPCLNGGTCAVASNMPDGFICRCPPG----FSGARCQS 1344 Score = 30.8 bits (68), Expect = 4.8 Identities = 11/25 (44%), Positives = 15/25 (60%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRC 696 D C + CQN G+CV+ +CRC Sbjct: 262 DDCPNHRCQNGGVCVDGVNTYNCRC 286 Score = 30.8 bits (68), Expect = 4.8 Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 12/55 (21%) Query: 679 CQNDGICVNVKGMASCRCISGHAFFYTGER--------CQAVQVHGSVLGMVIGG 725 CQ+ G+C+N C+C G+ Y E+ CQ HG+ IGG Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ----HGATCSDFIGG 1170 Score = 30.4 bits (67), Expect = 6.2 Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISG 699 D C +PC NDG C+++ C C G Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPG 636 >gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] Length = 236 Score = 47.8 bits (112), Expect = 4e-05 Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 6/47 (12%) Query: 671 RDPCDPNPCQNDGICV--NVKGMASCRCISGHAFFYTGERCQAVQVH 715 RDPC+ N CQN G CV + G A+CRC SG +TGE CQ H Sbjct: 26 RDPCEKNRCQNGGTCVAQAMLGKATCRCASG----FTGEDCQYSTSH 68 Score = 40.4 bits (93), Expect = 0.006 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 5/54 (9%) Query: 674 CD-PNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGT 726 CD P CQ+ G C+N+ G C+C+ G +TG+ C ++ V + V GGT Sbjct: 147 CDIPGHCQHGGTCLNLPGSYQCQCLQG----FTGQYCDSLYVPCAPSPCVNGGT 196 Score = 37.7 bits (86), Expect = 0.039 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C +PC N C V SC+C++G +TG++C+ Sbjct: 107 DACLSHPCANGSTCTTVANQFSCKCLTG----FTGQKCE 141 >gi|22027630 TNF receptor-associated factor 6 [Homo sapiens] Length = 522 Score = 47.4 bits (111), Expect = 5e-05 Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 27/162 (16%) Query: 435 VWTVRNFSQVL--ENTSKGDKLQSPRFYNSE-GYGFGVTLY---PNSRESSGYLRLAFHV 488 +W + NF L + K + SP FY + GY + L+ P ++ + Y+ L H Sbjct: 354 IWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHT 413 Query: 489 CSGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRP 547 GE D+ L WP + + +TILDQ E VR M A + + + RP Sbjct: 414 MQGEYDSHLPWPFQG-TIRLTILDQSEAPVRQNHEEIM----------DAKPELLAFQRP 462 Query: 548 SRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589 T + F G+ F+ + L++R+F+K+D L++ Sbjct: 463 ----TIPRNPKGF-----GYVTFMHLEALRQRTFIKDDTLLV 495 >gi|4759254 TNF receptor-associated factor 6 [Homo sapiens] Length = 522 Score = 47.4 bits (111), Expect = 5e-05 Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 27/162 (16%) Query: 435 VWTVRNFSQVL--ENTSKGDKLQSPRFYNSE-GYGFGVTLY---PNSRESSGYLRLAFHV 488 +W + NF L + K + SP FY + GY + L+ P ++ + Y+ L H Sbjct: 354 IWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHT 413 Query: 489 CSGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRP 547 GE D+ L WP + + +TILDQ E VR M A + + + RP Sbjct: 414 MQGEYDSHLPWPFQG-TIRLTILDQSEAPVRQNHEEIM----------DAKPELLAFQRP 462 Query: 548 SRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589 T + F G+ F+ + L++R+F+K+D L++ Sbjct: 463 ----TIPRNPKGF-----GYVTFMHLEALRQRTFIKDDTLLV 495 >gi|182508169 neuropilin 1 isoform a [Homo sapiens] Length = 923 Score = 47.0 bits (110), Expect = 6e-05 Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 6/119 (5%) Query: 309 TGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDST 368 TG G F+ + A L S ++Y + C+ F+Y M+GS L V +R Sbjct: 687 TGDGNFIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPE 746 Query: 369 GNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQK-FRYLFQGTKGDPQNSTGGIYLDDITL 426 + + QGD +WK V+L + K ++ +F+G G + + GGI +DDI++ Sbjct: 747 EYDQLVWMAIGHQGD---HWKEGRVLLHKSLKLYQVIFEGEIG--KGNLGGIAVDDISI 800 >gi|119220585 apical early endosomal glycoprotein precursor [Homo sapiens] Length = 1137 Score = 46.2 bits (108), Expect = 1e-04 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 21/168 (12%) Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA-EEA 327 C FE+ + C G DT W +S + + DHT TG G+F+ + A + Sbjct: 577 CNFER-DTCSWYPGHLSDTHWRWVES-RGPDHDHT-----TGQGHFVLLDPTDPLAWGHS 629 Query: 328 ALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHN 387 A L SR P +CL F+Y + G L + +RR+ + + G + Sbjct: 630 AHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEE------THLWSRSGTQGNR 683 Query: 388 WKIAHVVLKEE----QKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 W A L + +++ LF+G + G + LDD+ + PC Sbjct: 684 WHEAWATLSHQPGSHAQYQLLFEGLR---DGYHGTMALDDVAVRPGPC 728 Score = 38.9 bits (89), Expect = 0.018 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 22/173 (12%) Query: 267 DHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV-----DHTLLGQCTGAGYFMQFSTSS 321 ++C+FE ++ CG G + W Q +A DHT T G++M TS Sbjct: 732 NYCSFEDSD-CGFSPGGQGL--WRRQANASGHAAWGPPTDHTTE---TAQGHYMVVDTSP 785 Query: 322 GSAE--EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQT 379 + + A L S+ P + CL F+Y + L V++ R +V + Sbjct: 786 DALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEE-------RGRHQVLS 838 Query: 380 FQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCP 432 W++ + ++ E+ +R +F+ +S + LDD+ L + PCP Sbjct: 839 LSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSY--VALDDLLLQDGPCP 889 >gi|13124888 epidermal growth factor-like protein 6 precursor [Homo sapiens] Length = 553 Score = 45.1 bits (105), Expect = 2e-04 Identities = 49/211 (23%), Positives = 82/211 (38%), Gaps = 41/211 (19%) Query: 234 EFNSIIGQRLDF-SAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQ 292 EF I+ QR S ++ + LN +C+ H IC Q DD DW Sbjct: 376 EFGLILVQRKALTSKLEHKDLNISVDCSFNH-----------GICDWKQDREDDFDWNPA 424 Query: 293 DSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQ---CLQFFYK 349 D A G++M +G ++ L ++L P + Q CL F Y+ Sbjct: 425 DRDNA-------------IGFYMAVPALAGHKKDIGRL--KLLLPDLQPQSNFCLLFDYR 469 Query: 350 MTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKE--EQKFRYLFQG 407 + G +L V+V+ ++ K +D WK + L + + +F+ Sbjct: 470 LAGDKVGKLRVFVKNSNNALAWEKTT-------SEDEKWKTGKIQLYQGTDATKSIIFEA 522 Query: 408 TKGDPQNSTGGIYLDDITLTETPCPTGVWTV 438 +G + TG I +D + L CP + +V Sbjct: 523 ERG--KGKTGEIAVDGVLLVSGLCPDSLLSV 551 Score = 32.7 bits (73), Expect = 1.3 Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 11/54 (20%) Query: 656 ENTGPLEDHNWPQYFRDPCD---------PNPCQNDGICVNVKGMASCRCISGH 700 E GP + +P Y C P PCQ+ CVN G C C+SGH Sbjct: 73 ECVGPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGH 124 >gi|74136023 delta-like 1 homolog [Homo sapiens] Length = 383 Score = 43.5 bits (101), Expect = 7e-04 Identities = 15/35 (42%), Positives = 23/35 (65%) Query: 665 NWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISG 699 N+ + + C PNPC+NDG+C ++ G CRC +G Sbjct: 165 NFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAG 199 Score = 33.1 bits (74), Expect = 0.96 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 5/38 (13%) Query: 674 CDPNPCQNDGICVNV-KGMASCRCISGHAFFYTGERCQ 710 C PC N+G CV++ G+ C C G Y+G+ CQ Sbjct: 92 CSSAPCANNGTCVSLDDGLYECSCAPG----YSGKDCQ 125 >gi|22027612 TNF receptor-associated factor 2 [Homo sapiens] Length = 501 Score = 43.5 bits (101), Expect = 7e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 8/85 (9%) Query: 435 VWTVRNFSQVLENTSKG--DKLQSPRFYNSE-GYGFGVTLYPNSRESSG---YLRLAFHV 488 +W + +F++ + G + SP FY S GY + +Y N + +G +L L F V Sbjct: 355 IWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNG-DGTGRGTHLSLFFVV 413 Query: 489 CSGENDAILEWPVENRQVIITILDQ 513 G NDA+L WP N++V + +LDQ Sbjct: 414 MKGPNDALLRWPF-NQKVTLMLLDQ 437 >gi|148886654 polydom [Homo sapiens] Length = 3571 Score = 43.5 bits (101), Expect = 7e-04 Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 4/39 (10%) Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 D C P PC N+G+C ++ G C C SG YTG+RC+ Sbjct: 1233 DECSPLPCLNNGVCKDLVGEFICECPSG----YTGQRCE 1267 Score = 43.1 bits (100), Expect = 0.001 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFL 732 C NPC+N CV+ SC+C G ++G+RC+ Q G L + G G + L Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPG----FSGKRCETEQSTGFNLDFEVSGIYGYVML 1441 Score = 31.2 bits (69), Expect = 3.7 Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 4/37 (10%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710 C +PC N GICV+ C C+ G + G C+ Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKG----FVGLHCE 1305 Score = 31.2 bits (69), Expect = 3.7 Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 4/36 (11%) Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERC 709 C NPC N+ +C + G C+C G + G RC Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPG----FLGTRC 1342 >gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) precursor [Homo sapiens] Length = 539 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 9/105 (8%) Query: 646 GQPSRQKRSVENTGPLED----HNWPQYFRDPCD--PNPCQNDGICVNVKGM-ASCRCIS 698 G+P R S EN HN R CD P+ C N G C V+ + A CRC + Sbjct: 344 GEPGRDLASSENGTECRSGFVRHNGS--CRSVCDLFPSYCHNGGQCYLVENIGAFCRCNT 401 Query: 699 GHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQR 743 ++ G RC+++ V+ + +G A V+ L F + +++ Sbjct: 402 QDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKK 446 >gi|75709198 nephronectin [Homo sapiens] Length = 565 Score = 42.4 bits (98), Expect = 0.002 Identities = 40/167 (23%), Positives = 66/167 (39%), Gaps = 23/167 (13%) Query: 265 LLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324 L+ C F+ +CG I+ +D W G+ + G G A Sbjct: 418 LVHSCNFDHG-LCGWIREKDNDLHWEPIRDPAGGQYLTVSAAKAPG-----------GKA 465 Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDD 384 L R+++ CL F +K+TG S L V+VR+ + G + + Sbjct: 466 ARLVLPLGRLMHSG--DLCLSFRHKVTGLHSGTLQVFVRKHGAHG-------AALWGRNG 516 Query: 385 DHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431 H W+ + L+ +F+G K + TG I LDD++L + C Sbjct: 517 GHGWRQTQITLRGADIKSVVFKGEK--RRGHTGEIGLDDVSLKKGHC 561 >gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens] Length = 1241 Score = 40.8 bits (94), Expect = 0.005 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Query: 674 CDPNP--CQNDGICVNVKGM-ASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVI 730 CD P C NDG C + G A CRC G ++Y G+ C+ ++G+ I G++ Sbjct: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLL 1113 Query: 731 FLTFSII 737 + +II Sbjct: 1114 VIFSAII 1120 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,324,849 Number of Sequences: 37866 Number of extensions: 1374888 Number of successful extensions: 3890 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 80 Number of HSP's successfully gapped in prelim test: 72 Number of HSP's that attempted gapping in prelim test: 3203 Number of HSP's gapped (non-prelim): 726 length of query: 746 length of database: 18,247,518 effective HSP length: 110 effective length of query: 636 effective length of database: 14,082,258 effective search space: 8956316088 effective search space used: 8956316088 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.