Guide to the Human Genome
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Search of human proteins with 153070262

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153070262 meprin A alpha [Homo sapiens]
         (746 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153070262 meprin A alpha [Homo sapiens]                           1546   0.0  
gi|153070264 meprin A beta [Homo sapiens]                             514   e-145
gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]         122   9e-28
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...   105   2e-22
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...   105   2e-22
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...   105   2e-22
gi|6912724 tolloid-like 2 [Homo sapiens]                              104   3e-22
gi|22547221 tolloid-like 1 [Homo sapiens]                             103   4e-22
gi|24111244 MAM domain containing glycosylphosphatidylinositol a...    64   7e-10
gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]          59   2e-08
gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens]           59   2e-08
gi|223942069 enterokinase precursor [Homo sapiens]                     59   2e-08
gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho...    55   2e-07
gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho...    55   2e-07
gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho...    55   2e-07
gi|22027622 TNF receptor-associated factor 4 [Homo sapiens]            52   2e-06
gi|223278413 MAM domain containing 2 [Homo sapiens]                    52   3e-06
gi|24041035 notch 2 preproprotein [Homo sapiens]                       48   4e-05
gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]     48   4e-05
gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]            47   5e-05
gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]             47   5e-05
gi|182508169 neuropilin 1 isoform a [Homo sapiens]                     47   6e-05
gi|119220585 apical early endosomal glycoprotein precursor [Homo...    46   1e-04
gi|13124888 epidermal growth factor-like protein 6 precursor [Ho...    45   2e-04
gi|74136023 delta-like 1 homolog [Homo sapiens]                        44   7e-04
gi|22027612 TNF receptor-associated factor 2 [Homo sapiens]            44   7e-04
gi|148886654 polydom [Homo sapiens]                                    44   7e-04
gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ...    43   0.001
gi|75709198 nephronectin [Homo sapiens]                                42   0.002
gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]    41   0.005

>gi|153070262 meprin A alpha [Homo sapiens]
          Length = 746

 Score = 1546 bits (4002), Expect = 0.0
 Identities = 746/746 (100%), Positives = 746/746 (100%)

Query: 1   MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDIL 60
           MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDIL
Sbjct: 1   MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDIL 60

Query: 61  LQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYI 120
           LQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYI
Sbjct: 61  LQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYI 120

Query: 121 IFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW 180
           IFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW
Sbjct: 121 IFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW 180

Query: 181 DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIG 240
           DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIG
Sbjct: 181 DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIG 240

Query: 241 QRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV 300
           QRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV
Sbjct: 241 QRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV 300

Query: 301 DHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVV 360
           DHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVV
Sbjct: 301 DHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVV 360

Query: 361 WVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIY 420
           WVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIY
Sbjct: 361 WVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIY 420

Query: 421 LDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSG 480
           LDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSG
Sbjct: 421 LDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSG 480

Query: 481 YLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAIND 540
           YLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAIND
Sbjct: 481 YLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAIND 540

Query: 541 TVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLS 600
           TVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLS
Sbjct: 541 TVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLS 600

Query: 601 QTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGP 660
           QTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGP
Sbjct: 601 QTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGP 660

Query: 661 LEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLG 720
           LEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLG
Sbjct: 661 LEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLG 720

Query: 721 MVIGGTAGVIFLTFSIIAILSQRPRK 746
           MVIGGTAGVIFLTFSIIAILSQRPRK
Sbjct: 721 MVIGGTAGVIFLTFSIIAILSQRPRK 746


>gi|153070264 meprin A beta [Homo sapiens]
          Length = 701

 Score =  514 bits (1324), Expect = e-145
 Identities = 266/578 (46%), Positives = 367/578 (63%), Gaps = 16/578 (2%)

Query: 34  DADFGEQKDISEINLAAGLDLFQGDILLQKS--RNGLRDPNTRWTFPIPYILADNLGLNA 91
           D D G  +DI +IN   GLDLF+GDI L ++  RN +     RW   IPY+L D+L +NA
Sbjct: 28  DVDGGMDQDIFDINEGLGLDLFEGDIRLDRAQIRNSIIGEKYRWPHTIPYVLEDSLEMNA 87

Query: 92  KGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVG-QNISIGQGCAYK 150
           KG IL AFE +RLK+C+DFKP+ GE++YI   +  GCWS VG++ VG Q +SIG  C   
Sbjct: 88  KGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRI 147

Query: 151 AIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYES 210
           A ++HE LHALGF+HEQSR+DRDDYV I WD+ILSG +HNF+TY D +   LN PYDY S
Sbjct: 148 ATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTS 207

Query: 211 LMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCT 270
           +MHY   +F +N + PTI  +I +F  +IGQR+DFS  DL +LN++YNC+++ + +D C+
Sbjct: 208 VMHYSKTAF-QNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCS 266

Query: 271 FEKANICGMIQGTRDDTDWAHQDSAQAG-EVDHTLLGQCTGAGYFMQFSTSSGSAEEAAL 329
           FE  N+CGMIQ + D+ DW        G E DH+ +GQC G+G+FM F +SS +    A+
Sbjct: 267 FELENVCGMIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAV 326

Query: 330 LESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWK 389
           LESR LYPKR  QCLQF+   +GS SD+L +++R   +      L  V+  +     +W+
Sbjct: 327 LESRTLYPKRGFQCLQFYLYNSGSESDQLNIYIREYSADNVDGNLTLVEEIKEIPTGSWQ 386

Query: 390 IAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTS 449
           + HV LK  +KFR +F+G KG    S GG+ +DDI L+ET CP  +W +RNF+Q +   S
Sbjct: 387 LYHVTLKVTKKFRVVFEGRKGSGA-SLGGLSIDDINLSETRCPHHIWHIRNFTQFI--GS 443

Query: 450 KGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIIT 509
               L SP FY+S+GY F + L      ++G   + FH+ SG ND  L+WP   +Q  +T
Sbjct: 444 PNGTLYSPPFYSSKGYAFQIYLNLAHVTNAG---IYFHLISGANDDQLQWPCPWQQATMT 500

Query: 510 ILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGT---YHTDCNCFRSIDLG 566
           +LDQ PD+R RMS+    TT    T+   N    WDRPS+VGT   +       R    G
Sbjct: 501 LLDQNPDIRQRMSNQRSITTDPFMTTD--NGNYFWDRPSKVGTVALFSNGTQFRRGGGYG 558

Query: 567 WSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEV 604
            S FI+H+ LK R F+K DD+ I +  EDI+HL+ T++
Sbjct: 559 TSAFITHERLKSRDFIKGDDVYILLTVEDISHLNSTQI 596


>gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]
          Length = 431

 Score =  122 bits (307), Expect = 9e-28
 Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 22/236 (9%)

Query: 41  KDISEINLAAGLD-------LFQGDILLQKSRNGLRDPNTRWTF------PIPYILADNL 87
           KDI  IN    L+       L +GDI+       L   + +W         +P++L+   
Sbjct: 53  KDIPAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKY 112

Query: 88  GLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGC 147
              ++  IL A   F   +C+ F  Y+ +  +I      GC+S VG     Q +S+   C
Sbjct: 113 DEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTC 172

Query: 148 AYKA--IIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTP 205
             K   I+ HE++H LGF+HE +R DRD Y+ + W++IL G++ NF     S   ++ TP
Sbjct: 173 LQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSS---NMLTP 229

Query: 206 YDYESLMHYQPFSFNKNASVPTITAK-IPEFNSIIGQRLDFSAIDLERLNRMYNCT 260
           YDY S+MHY   +F++   +PTIT    P  +  IGQR + SA D+ R+ ++Y C+
Sbjct: 230 YDYSSVMHYGRLAFSRR-GLPTITPLWAPSVH--IGQRWNLSASDITRVLKLYGCS 282


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
           sapiens]
          Length = 730

 Score =  105 bits (262), Expect = 2e-22
 Identities = 65/197 (32%), Positives = 99/197 (50%), Gaps = 6/197 (3%)

Query: 79  IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137
           IP+++  N   + +     A   +   +CV F     E SYI+F     GC S VG +  
Sbjct: 135 IPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGG 194

Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196
           G Q ISIG+ C    I+ HE+ H +GF+HE +R DRD +V+I  + I  G ++NF   + 
Sbjct: 195 GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEP 254

Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSI---IGQRLDFSAIDLERL 253
             +  L   YD++S+MHY   +F++   + TI  K  E N +   IGQR   S  D+ + 
Sbjct: 255 QEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKY-EVNGVKPPIGQRTRLSKGDIAQA 313

Query: 254 NRMYNCTTTHTLLDHCT 270
            ++Y C      L   T
Sbjct: 314 RKLYKCPACGETLQDST 330


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
           sapiens]
          Length = 823

 Score =  105 bits (262), Expect = 2e-22
 Identities = 65/197 (32%), Positives = 99/197 (50%), Gaps = 6/197 (3%)

Query: 79  IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137
           IP+++  N   + +     A   +   +CV F     E SYI+F     GC S VG +  
Sbjct: 135 IPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGG 194

Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196
           G Q ISIG+ C    I+ HE+ H +GF+HE +R DRD +V+I  + I  G ++NF   + 
Sbjct: 195 GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEP 254

Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSI---IGQRLDFSAIDLERL 253
             +  L   YD++S+MHY   +F++   + TI  K  E N +   IGQR   S  D+ + 
Sbjct: 255 QEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKY-EVNGVKPPIGQRTRLSKGDIAQA 313

Query: 254 NRMYNCTTTHTLLDHCT 270
            ++Y C      L   T
Sbjct: 314 RKLYKCPACGETLQDST 330


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
           sapiens]
          Length = 986

 Score =  105 bits (262), Expect = 2e-22
 Identities = 65/197 (32%), Positives = 99/197 (50%), Gaps = 6/197 (3%)

Query: 79  IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137
           IP+++  N   + +     A   +   +CV F     E SYI+F     GC S VG +  
Sbjct: 135 IPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGG 194

Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196
           G Q ISIG+ C    I+ HE+ H +GF+HE +R DRD +V+I  + I  G ++NF   + 
Sbjct: 195 GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEP 254

Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSI---IGQRLDFSAIDLERL 253
             +  L   YD++S+MHY   +F++   + TI  K  E N +   IGQR   S  D+ + 
Sbjct: 255 QEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKY-EVNGVKPPIGQRTRLSKGDIAQA 313

Query: 254 NRMYNCTTTHTLLDHCT 270
            ++Y C      L   T
Sbjct: 314 RKLYKCPACGETLQDST 330


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score =  104 bits (260), Expect = 3e-22
 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 4/196 (2%)

Query: 79  IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQ-QFDGCWSEVGDQHV 137
           IPY++  N   + +     A   +   +CV F     E S+I+F  +  GC S VG +  
Sbjct: 164 IPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGG 223

Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196
           G Q ISIG+ C    I+ HE+ H +GF+HE +R DRD +V I  + I  G ++NF   + 
Sbjct: 224 GPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEA 283

Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPE--FNSIIGQRLDFSAIDLERLN 254
             ++ L   YD++S+MHY   +F++   + TI  +  +      IGQR+  S  D+ +  
Sbjct: 284 GEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQAR 343

Query: 255 RMYNCTTTHTLLDHCT 270
           ++Y C      L   T
Sbjct: 344 KLYKCPACGETLQDTT 359


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score =  103 bits (258), Expect = 4e-22
 Identities = 61/185 (32%), Positives = 94/185 (50%), Gaps = 4/185 (2%)

Query: 79  IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFD-GCWSEVGDQHV 137
           IPY++  N   + +     A   +   +CV F     E SYI+F     GC S VG +  
Sbjct: 162 IPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEESYIVFTYRPCGCCSYVGRRGN 221

Query: 138 G-QNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDD 196
           G Q ISIG+ C    I+ HE+ H +GF+HE +R DRD++V I  + I  G ++NF   + 
Sbjct: 222 GPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEP 281

Query: 197 SLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPE--FNSIIGQRLDFSAIDLERLN 254
             +  L   YD++S+MHY   +F++   + TI     +      IGQR   S  D+ +  
Sbjct: 282 GEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQAR 341

Query: 255 RMYNC 259
           ++Y C
Sbjct: 342 KLYRC 346


>gi|24111244 MAM domain containing glycosylphosphatidylinositol
           anchor 1 [Homo sapiens]
          Length = 955

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 49/170 (28%), Positives = 69/170 (40%), Gaps = 11/170 (6%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLG-----QCTGAGYFMQFSTS-SG 322
           C FE   ICG  Q   D+ DW  Q++           G       T  GY+M   TS   
Sbjct: 753 CHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPR 812

Query: 323 SAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQG 382
              + A L S +     K  C+ FFY M G     L + VR   S           +  G
Sbjct: 813 ELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVR---SRNKGALDTHAWSLSG 869

Query: 383 DDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCP 432
           +  + W+ AHV +     F+ +F+G +G      G I +DD+TL +  CP
Sbjct: 870 NKGNVWQQAHVPISPSGPFQIIFEGVRG--PGYLGDIAIDDVTLKKGECP 917


>gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]
          Length = 956

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 19/178 (10%)

Query: 268 HCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLG-----QCTGAGYFMQFSTSSG 322
           HC FE  NIC   Q   D+ DW  Q +A          G       +  G++M   TS  
Sbjct: 747 HCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRP 806

Query: 323 SAE-EAALLESRILY--------PKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRK 373
             E E A L S +          P     C  FFY M G     L V++R    T     
Sbjct: 807 RLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENP 866

Query: 374 LVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
           L    +  G+    W  AHV +     F+ +F+G +G      G I +DD+++ E  C
Sbjct: 867 L---WSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRG--PGIEGDIAIDDVSIAEGEC 919


>gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens]
          Length = 727

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 19/178 (10%)

Query: 268 HCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLG-----QCTGAGYFMQFSTSSG 322
           HC FE  NIC   Q   D+ DW  Q +A          G       +  G++M   TS  
Sbjct: 518 HCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRP 577

Query: 323 SAE-EAALLESRILY--------PKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRK 373
             E E A L S +          P     C  FFY M G     L V++R    T     
Sbjct: 578 RLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENP 637

Query: 374 LVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
           L    +  G+    W  AHV +     F+ +F+G +G      G I +DD+++ E  C
Sbjct: 638 L---WSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRG--PGIEGDIAIDDVSIAEGEC 690


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 17/169 (10%)

Query: 268 HCTFEKANICGMIQGTRDDTDWAHQDSAQAG-----EVDHTLLGQCTGAGYFMQFSTSSG 322
           +C FE    C  +Q   DD +W     +          DHT       +G+++   T  G
Sbjct: 346 NCNFEDG-FCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTF---GNASGFYISTPTGPG 401

Query: 323 SAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQG 382
             +E   L S  L P  +  CL F+Y M G    +L + +  D    N+ K V  +  +G
Sbjct: 402 GRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQ---NMEKTVFQK--EG 456

Query: 383 DDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
           +   NW    V L E  KF+  F   K         I LDDI+LT   C
Sbjct: 457 NYGDNWNYGQVTLNETVKFKVAFNAFK---NKILSDIALDDISLTYGIC 502


>gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1542

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324
           C FE   IC   Q  +DD DW        +   G +    LG   G   +++ S      
Sbjct: 230 CNFE-TGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQ 288

Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVR-RDDSTGNVRKLVKVQTFQGD 383
           + AALL   +     K    +F+Y M G    RL ++ R   DS G +     +    G+
Sbjct: 289 DSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQL-----LWQIFGN 343

Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428
             + W   H+ +   Q F+ L + + GD    TG I +DD++  +
Sbjct: 344 QGNRWIRKHLNISSRQPFQILVEASVGD--GFTGDIAIDDLSFMD 386



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 34/255 (13%)

Query: 265 LLDHCTFEKANICGMIQ---------------GTRDDTDWAHQDSAQAGEVDHTLLGQCT 309
           +++ C+FEK ++C   Q               G  +     H +      VDHT   Q T
Sbjct: 451 VMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT---QNT 507

Query: 310 GAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTG 369
             G+++   +S+G   + A + + I+     +  L F+  M G+    L V +++D+ T 
Sbjct: 508 TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTS 567

Query: 370 NVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTET 429
                 K+    G     WK A V L      + +F+  +G   +  G + +DDI+  + 
Sbjct: 568 ------KLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRG--ISYIGDVAVDDISFQDC 619

Query: 430 P---CPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAF 486
                P    T   F    ++    DKL    F N        T +   R SSG     F
Sbjct: 620 SPLLSPERKCTDHEFMCANKHCIAKDKLCD--FVNDCADNSDETTF-ICRTSSGRCDFEF 676

Query: 487 HVCS--GENDAILEW 499
            +CS   E D   +W
Sbjct: 677 DLCSWKQEKDEDFDW 691



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 48/165 (29%), Positives = 73/165 (44%), Gaps = 15/165 (9%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSA--QAGE---VDHTLLGQCTGAGYFMQFSTSSGS 323
           C FE  ++C   Q   +D DW  + S+   AG     DHTL G  +G   F+  S     
Sbjct: 672 CDFE-FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTL-GNSSGHYIFIN-SLFPQQ 728

Query: 324 AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383
              AA + S ++  + K   + F Y M G+    L +   +   T   + L+ +   QG+
Sbjct: 729 PMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLM--QVSVTNQTKVLLNLTVEQGN 786

Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428
               W+   + L  ++ F+  F+G  G  Q   G I LDDI LTE
Sbjct: 787 F---WRREELSLFGDEDFQLKFEGRVGKGQR--GDIALDDIVLTE 826



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 258  NCTTTHTLLDHCTFEKAN-----ICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQC 308
            +C    +    C FE ++      C + Q + DD DWA        A   + DHT     
Sbjct: 1153 HCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHT----- 1207

Query: 309  TGAGYFMQFSTSSGSAE-EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDS 367
             G+G    +  SSGS E   A + +   +P     C   F+     P    ++ V   + 
Sbjct: 1208 PGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEE 1267

Query: 368  TGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLT 427
            +G     + V +  G+    W    V L     F+  F+       N    I LDDI+ T
Sbjct: 1268 SG---LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDG--NEDIFIALDDISFT 1322

Query: 428  ETPCPTG 434
               C TG
Sbjct: 1323 -PECVTG 1328


>gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1817

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324
           C FE   IC   Q  +DD DW        +   G +    LG   G   +++ S      
Sbjct: 505 CNFE-TGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQ 563

Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVR-RDDSTGNVRKLVKVQTFQGD 383
           + AALL   +     K    +F+Y M G    RL ++ R   DS G +     +    G+
Sbjct: 564 DSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQL-----LWQIFGN 618

Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428
             + W   H+ +   Q F+ L + + GD    TG I +DD++  +
Sbjct: 619 QGNRWIRKHLNISSRQPFQILVEASVGD--GFTGDIAIDDLSFMD 661



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 34/255 (13%)

Query: 265 LLDHCTFEKANICGMIQ---------------GTRDDTDWAHQDSAQAGEVDHTLLGQCT 309
           +++ C+FEK ++C   Q               G  +     H +      VDHT   Q T
Sbjct: 726 VMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT---QNT 782

Query: 310 GAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTG 369
             G+++   +S+G   + A + + I+     +  L F+  M G+    L V +++D+ T 
Sbjct: 783 TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTS 842

Query: 370 NVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTET 429
                 K+    G     WK A V L      + +F+  +G   +  G + +DDI+  + 
Sbjct: 843 ------KLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRG--ISYIGDVAVDDISFQDC 894

Query: 430 P---CPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAF 486
                P    T   F    ++    DKL    F N        T +   R SSG     F
Sbjct: 895 SPLLSPERKCTDHEFMCANKHCIAKDKLCD--FVNDCADNSDETTF-ICRTSSGRCDFEF 951

Query: 487 HVCS--GENDAILEW 499
            +CS   E D   +W
Sbjct: 952 DLCSWKQEKDEDFDW 966



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 15/165 (9%)

Query: 269  CTFEKANICGMIQGTRDDTDWAHQDSA--QAGE---VDHTLLGQCTGAGYFMQFSTSSGS 323
            C FE  ++C   Q   +D DW  + S+   AG     DHTL G  +G   F++ S     
Sbjct: 947  CDFE-FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTL-GNSSGHYIFIK-SLFPQQ 1003

Query: 324  AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383
               AA + S ++  + K   + F Y M G+    L +   +   T   + L+ +   QG+
Sbjct: 1004 PMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLM--QVSVTNQTKVLLNLTVEQGN 1061

Query: 384  DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428
                W+   + L  ++ F+  F+G  G  Q   G I LDDI LTE
Sbjct: 1062 F---WRREELSLFGDEDFQLKFEGRVGKGQR--GDIALDDIVLTE 1101



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 258  NCTTTHTLLDHCTFEKAN-----ICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQC 308
            +C    +    C FE ++      C + Q + DD DWA        A   + DHT     
Sbjct: 1428 HCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHT----- 1482

Query: 309  TGAGYFMQFSTSSGSAE-EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDS 367
             G+G    +  SSGS E   A + +   +P     C   F+     P    ++ V   + 
Sbjct: 1483 PGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEE 1542

Query: 368  TGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLT 427
            +G     + V +  G+    W    V L     F+  F+       N    I LDDI+ T
Sbjct: 1543 SG---LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDG--NEDIFIALDDISFT 1597

Query: 428  ETPCPTG 434
               C TG
Sbjct: 1598 -PECVTG 1603


>gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1817

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324
           C FE   IC   Q  +DD DW        +   G +    LG   G   +++ S      
Sbjct: 505 CNFE-TGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQ 563

Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVR-RDDSTGNVRKLVKVQTFQGD 383
           + AALL   +     K    +F+Y M G    RL ++ R   DS G +     +    G+
Sbjct: 564 DSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQL-----LWQIFGN 618

Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428
             + W   H+ +   Q F+ L + + GD    TG I +DD++  +
Sbjct: 619 QGNRWIRKHLNISSRQPFQILVEASVGD--GFTGDIAIDDLSFMD 661



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 34/255 (13%)

Query: 265 LLDHCTFEKANICGMIQ---------------GTRDDTDWAHQDSAQAGEVDHTLLGQCT 309
           +++ C+FEK ++C   Q               G  +     H +      VDHT   Q T
Sbjct: 726 VMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT---QNT 782

Query: 310 GAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTG 369
             G+++   +S+G   + A + + I+     +  L F+  M G+    L V +++D+ T 
Sbjct: 783 TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTS 842

Query: 370 NVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTET 429
                 K+    G     WK A V L      + +F+  +G   +  G + +DDI+  + 
Sbjct: 843 ------KLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRG--ISYIGDVAVDDISFQDC 894

Query: 430 P---CPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAF 486
                P    T   F    ++    DKL    F N        T +   R SSG     F
Sbjct: 895 SPLLSPERKCTDHEFMCANKHCIAKDKLCD--FVNDCADNSDETTF-ICRTSSGRCDFEF 951

Query: 487 HVCS--GENDAILEW 499
            +CS   E D   +W
Sbjct: 952 DLCSWKQEKDEDFDW 966



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 15/165 (9%)

Query: 269  CTFEKANICGMIQGTRDDTDWAHQDSA--QAGE---VDHTLLGQCTGAGYFMQFSTSSGS 323
            C FE  ++C   Q   +D DW  + S+   AG     DHTL G  +G   F++ S     
Sbjct: 947  CDFE-FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTL-GNSSGHYIFIK-SLFPQQ 1003

Query: 324  AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383
               AA + S ++  + K   + F Y M G+    L +   +   T   + L+ +   QG+
Sbjct: 1004 PMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLM--QVSVTNQTKVLLNLTVEQGN 1061

Query: 384  DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTE 428
                W+   + L  ++ F+  F+G  G  Q   G I LDDI LTE
Sbjct: 1062 F---WRREELSLFGDEDFQLKFEGRVGKGQR--GDIALDDIVLTE 1101



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 258  NCTTTHTLLDHCTFEKAN-----ICGMIQGTRDDTDWAHQD----SAQAGEVDHTLLGQC 308
            +C    +    C FE ++      C + Q + DD DWA        A   + DHT     
Sbjct: 1428 HCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHT----- 1482

Query: 309  TGAGYFMQFSTSSGSAE-EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDS 367
             G+G    +  SSGS E   A + +   +P     C   F+     P    ++ V   + 
Sbjct: 1483 PGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEE 1542

Query: 368  TGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLT 427
            +G     + V +  G+    W    V L     F+  F+       N    I LDDI+ T
Sbjct: 1543 SG---LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDG--NEDIFIALDDISFT 1597

Query: 428  ETPCPTG 434
               C TG
Sbjct: 1598 -PECVTG 1603


>gi|22027622 TNF receptor-associated factor 4 [Homo sapiens]
          Length = 470

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 41/161 (25%), Positives = 74/161 (45%), Gaps = 19/161 (11%)

Query: 435 VWTVRNFSQVLENTSKGDKLQ--SPRFYNSE-GYGFGVTLYPNSRESSG--YLRLAFHVC 489
           +W + ++ + L+       L+  SP FY  + GY   V+ + N   S    +L L   V 
Sbjct: 311 IWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVL 370

Query: 490 SGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPS 548
            G  D +LEWP   R+V  ++LDQ +P +               H +   +    W    
Sbjct: 371 PGAFDNLLEWPFA-RRVTFSLLDQSDPGL-----------AKPQHVTETFHPDPNWKNFQ 418

Query: 549 RVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589
           + GT+    +   S+  G+  FISHQ +++R+++++D + I
Sbjct: 419 KPGTWRGSLD-ESSLGFGYPKFISHQDIRKRNYVRDDAVFI 458


>gi|223278413 MAM domain containing 2 [Homo sapiens]
          Length = 686

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 17/168 (10%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQ-----DSAQAGEVDHTLLGQCTGAGYFMQFSTSSGS 323
           CTFE+   C   Q  R+ + W  +      S    + DHT     TG GY+M    S   
Sbjct: 509 CTFEQDE-CTFTQEKRNRSSWHRRRGETPTSYTGPKGDHT-----TGVGYYMYIEASHMV 562

Query: 324 AEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGD 383
             + A L SR L     + CL FFY M G  +  L V++++++ +    +   +   +G+
Sbjct: 563 YGQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDS----EESLLWRRRGE 618

Query: 384 DDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
              +W  A +    E++ + +F+  +G    S   I +DD+     PC
Sbjct: 619 QSISWLRALIEYSCERQHQIIFEAIRGVSIRS--DIAIDDVKFQAGPC 664



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 25/173 (14%)

Query: 269 CTFEKANICGMIQGTRDDTDW-----AHQDSAQAGEVDHTLLGQCTGAGYFMQF-STSSG 322
           C FE+ ++CG +     + +W     + ++       DHT   +    G++M   S    
Sbjct: 170 CDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSE---LGHYMYVDSVYVK 226

Query: 323 SAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQG 382
             +E A L S  L       CL F+Y++     +   ++ R  D  G   ++ K      
Sbjct: 227 HFQEVAQLISP-LTTAPMAGCLSFYYQIQQGNDNVFSLYTR--DVAGLYEEIWKADR--- 280

Query: 383 DDDHNWKIAHVVLKE----EQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
             +  W +A V        E  F   F G KG      G + LDDI+ +   C
Sbjct: 281 PGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKG------GYVALDDISFSPVHC 327


>gi|24041035 notch 2 preproprotein [Homo sapiens]
          Length = 2471

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 6/47 (12%)

Query: 671 RDPCDPNPCQNDGICV--NVKGMASCRCISGHAFFYTGERCQAVQVH 715
           RDPC+ N CQN G CV   + G A+CRC SG    +TGE CQ    H
Sbjct: 65  RDPCEKNRCQNGGTCVAQAMLGKATCRCASG----FTGEDCQYSTSH 107



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 4/39 (10%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           D C  NPCQN G C++     SC C+ G    +TG++CQ
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPG----FTGDKCQ 947



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 5/54 (9%)

Query: 674 CD-PNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGT 726
           CD P  CQ+ G C+N+ G   C+C  G    +TG+ C ++ V  +    V GGT
Sbjct: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQG----FTGQYCDSLYVPCAPSPCVNGGT 235



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           D C  +PC N   C  V    SC+C++G    +TG++C+
Sbjct: 146 DACLSHPCANGSTCTTVANQFSCKCLTG----FTGQKCE 180



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 4/34 (11%)

Query: 677 NPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           NPC++ G CVN  G   C C+ G    Y G RC+
Sbjct: 425 NPCEHAGKCVNTDGAFHCECLKG----YAGPRCE 454



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 674  CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAV 712
            C  +PC N+G CV+  G   C C  G    YTG+ CQ +
Sbjct: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLG----YTGKNCQTL 1063



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 4/41 (9%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAV 712
           D C  NPC N G C +     +C C+      YTG+ CQ V
Sbjct: 797 DECASNPCLNQGTCFDDISGYTCHCV----LPYTGKNCQTV 833



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 6/40 (15%)

Query: 672 DPC--DPNPCQNDGICVNVKGMASCRCISGHAFFYTGERC 709
           D C   PN CQN G C N  G   C C++G    ++G+ C
Sbjct: 300 DECLLQPNACQNGGTCANRNGGYGCVCVNG----WSGDDC 335



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 14/31 (45%), Positives = 17/31 (54%)

Query: 674  CDPNPCQNDGICVNVKGMASCRCISGHAFFY 704
            C  +PC+N G CV  K  + C C SG A  Y
Sbjct: 1067 CSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 6/39 (15%)

Query: 673 PCDPNPCQNDGICVNVKGMAS--CRCISGHAFFYTGERC 709
           PC PNPC+N  +C       S  C C  G    + G+RC
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAPG----WQGQRC 870



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 4/39 (10%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           D C   PC N G+C N +G   C C  G    ++G  C+
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPG----FSGMDCE 909



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 5/40 (12%)

Query: 672  DPCDPNP-CQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
            D C   P C N G C++  G  SCRC+ G    + GERC+
Sbjct: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPG----FAGERCE 1262



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 4/40 (10%)

Query: 671 RDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           ++ C  NPCQN G C N+     C C  G    + G  CQ
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKG----FKGYNCQ 793



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 672  DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
            D C  NPCQ+   C +  G   C C+ G    Y G  C+
Sbjct: 1151 DECASNPCQHGATCSDFIGGYRCECVPG----YQGVNCE 1185



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 12/32 (37%), Positives = 16/32 (50%)

Query: 668  QYFRDPCDPNPCQNDGICVNVKGMASCRCISG 699
            +Y  D C   PCQN G C+++     C C  G
Sbjct: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 1216



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           C  +PCQND  C++  G  +C C+ G    + G  C+
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPG----FKGVHCE 492



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 4/37 (10%)

Query: 674 CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           C  NPC N+G CV+      C C  G    +TG  CQ
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPG----FTGPVCQ 530



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 7/45 (15%)

Query: 670  FRDPCDPNPCQNDGICVNVKGMAS---CRCISGHAFFYTGERCQA 711
            F D C   PC N G C     M     CRC  G    ++G RCQ+
Sbjct: 1304 FVDVCPQMPCLNGGTCAVASNMPDGFICRCPPG----FSGARCQS 1344



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 11/25 (44%), Positives = 15/25 (60%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRC 696
           D C  + CQN G+CV+     +CRC
Sbjct: 262 DDCPNHRCQNGGVCVDGVNTYNCRC 286



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 12/55 (21%)

Query: 679  CQNDGICVNVKGMASCRCISGHAFFYTGER--------CQAVQVHGSVLGMVIGG 725
            CQ+ G+C+N      C+C  G+   Y  E+        CQ    HG+     IGG
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ----HGATCSDFIGG 1170



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 11/28 (39%), Positives = 15/28 (53%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISG 699
           D C  +PC NDG C+++     C C  G
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPG 636


>gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]
          Length = 236

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 6/47 (12%)

Query: 671 RDPCDPNPCQNDGICV--NVKGMASCRCISGHAFFYTGERCQAVQVH 715
           RDPC+ N CQN G CV   + G A+CRC SG    +TGE CQ    H
Sbjct: 26  RDPCEKNRCQNGGTCVAQAMLGKATCRCASG----FTGEDCQYSTSH 68



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 5/54 (9%)

Query: 674 CD-PNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGT 726
           CD P  CQ+ G C+N+ G   C+C+ G    +TG+ C ++ V  +    V GGT
Sbjct: 147 CDIPGHCQHGGTCLNLPGSYQCQCLQG----FTGQYCDSLYVPCAPSPCVNGGT 196



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 672 DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
           D C  +PC N   C  V    SC+C++G    +TG++C+
Sbjct: 107 DACLSHPCANGSTCTTVANQFSCKCLTG----FTGQKCE 141


>gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]
          Length = 522

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 27/162 (16%)

Query: 435 VWTVRNFSQVL--ENTSKGDKLQSPRFYNSE-GYGFGVTLY---PNSRESSGYLRLAFHV 488
           +W + NF   L  +   K   + SP FY  + GY   + L+   P ++  + Y+ L  H 
Sbjct: 354 IWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHT 413

Query: 489 CSGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRP 547
             GE D+ L WP +   + +TILDQ E  VR      M           A  + + + RP
Sbjct: 414 MQGEYDSHLPWPFQG-TIRLTILDQSEAPVRQNHEEIM----------DAKPELLAFQRP 462

Query: 548 SRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589
               T   +   F     G+  F+  + L++R+F+K+D L++
Sbjct: 463 ----TIPRNPKGF-----GYVTFMHLEALRQRTFIKDDTLLV 495


>gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
          Length = 522

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 27/162 (16%)

Query: 435 VWTVRNFSQVL--ENTSKGDKLQSPRFYNSE-GYGFGVTLY---PNSRESSGYLRLAFHV 488
           +W + NF   L  +   K   + SP FY  + GY   + L+   P ++  + Y+ L  H 
Sbjct: 354 IWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHT 413

Query: 489 CSGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRP 547
             GE D+ L WP +   + +TILDQ E  VR      M           A  + + + RP
Sbjct: 414 MQGEYDSHLPWPFQG-TIRLTILDQSEAPVRQNHEEIM----------DAKPELLAFQRP 462

Query: 548 SRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589
               T   +   F     G+  F+  + L++R+F+K+D L++
Sbjct: 463 ----TIPRNPKGF-----GYVTFMHLEALRQRTFIKDDTLLV 495


>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
          Length = 923

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 6/119 (5%)

Query: 309 TGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDST 368
           TG G F+          + A L S ++Y +    C+ F+Y M+GS    L V +R     
Sbjct: 687 TGDGNFIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPE 746

Query: 369 GNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQK-FRYLFQGTKGDPQNSTGGIYLDDITL 426
              + +      QGD   +WK   V+L +  K ++ +F+G  G  + + GGI +DDI++
Sbjct: 747 EYDQLVWMAIGHQGD---HWKEGRVLLHKSLKLYQVIFEGEIG--KGNLGGIAVDDISI 800


>gi|119220585 apical early endosomal glycoprotein precursor [Homo
           sapiens]
          Length = 1137

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 21/168 (12%)

Query: 269 CTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA-EEA 327
           C FE+ + C    G   DT W   +S +  + DHT     TG G+F+    +   A   +
Sbjct: 577 CNFER-DTCSWYPGHLSDTHWRWVES-RGPDHDHT-----TGQGHFVLLDPTDPLAWGHS 629

Query: 328 ALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHN 387
           A L SR   P    +CL F+Y + G     L + +RR+           + +  G   + 
Sbjct: 630 AHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEE------THLWSRSGTQGNR 683

Query: 388 WKIAHVVLKEE----QKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
           W  A   L  +     +++ LF+G +       G + LDD+ +   PC
Sbjct: 684 WHEAWATLSHQPGSHAQYQLLFEGLR---DGYHGTMALDDVAVRPGPC 728



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 22/173 (12%)

Query: 267 DHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEV-----DHTLLGQCTGAGYFMQFSTSS 321
           ++C+FE ++ CG   G +    W  Q +A          DHT     T  G++M   TS 
Sbjct: 732 NYCSFEDSD-CGFSPGGQGL--WRRQANASGHAAWGPPTDHTTE---TAQGHYMVVDTSP 785

Query: 322 GSAE--EAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQT 379
            +    + A L S+   P  +  CL F+Y  +      L V++         R   +V +
Sbjct: 786 DALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEE-------RGRHQVLS 838

Query: 380 FQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCP 432
                   W++  + ++ E+ +R +F+       +S   + LDD+ L + PCP
Sbjct: 839 LSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSY--VALDDLLLQDGPCP 889


>gi|13124888 epidermal growth factor-like protein 6 precursor [Homo
           sapiens]
          Length = 553

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 49/211 (23%), Positives = 82/211 (38%), Gaps = 41/211 (19%)

Query: 234 EFNSIIGQRLDF-SAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQ 292
           EF  I+ QR    S ++ + LN   +C+  H            IC   Q   DD DW   
Sbjct: 376 EFGLILVQRKALTSKLEHKDLNISVDCSFNH-----------GICDWKQDREDDFDWNPA 424

Query: 293 DSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQ---CLQFFYK 349
           D   A              G++M     +G  ++   L  ++L P  + Q   CL F Y+
Sbjct: 425 DRDNA-------------IGFYMAVPALAGHKKDIGRL--KLLLPDLQPQSNFCLLFDYR 469

Query: 350 MTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKE--EQKFRYLFQG 407
           + G    +L V+V+  ++     K          +D  WK   + L +  +     +F+ 
Sbjct: 470 LAGDKVGKLRVFVKNSNNALAWEKTT-------SEDEKWKTGKIQLYQGTDATKSIIFEA 522

Query: 408 TKGDPQNSTGGIYLDDITLTETPCPTGVWTV 438
            +G  +  TG I +D + L    CP  + +V
Sbjct: 523 ERG--KGKTGEIAVDGVLLVSGLCPDSLLSV 551



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 11/54 (20%)

Query: 656 ENTGPLEDHNWPQYFRDPCD---------PNPCQNDGICVNVKGMASCRCISGH 700
           E  GP +   +P Y    C          P PCQ+   CVN  G   C C+SGH
Sbjct: 73  ECVGPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGH 124


>gi|74136023 delta-like 1 homolog [Homo sapiens]
          Length = 383

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 15/35 (42%), Positives = 23/35 (65%)

Query: 665 NWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISG 699
           N+ +   + C PNPC+NDG+C ++ G   CRC +G
Sbjct: 165 NFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAG 199



 Score = 33.1 bits (74), Expect = 0.96
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 674 CDPNPCQNDGICVNV-KGMASCRCISGHAFFYTGERCQ 710
           C   PC N+G CV++  G+  C C  G    Y+G+ CQ
Sbjct: 92  CSSAPCANNGTCVSLDDGLYECSCAPG----YSGKDCQ 125


>gi|22027612 TNF receptor-associated factor 2 [Homo sapiens]
          Length = 501

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 8/85 (9%)

Query: 435 VWTVRNFSQVLENTSKG--DKLQSPRFYNSE-GYGFGVTLYPNSRESSG---YLRLAFHV 488
           +W + +F++  +    G    + SP FY S  GY   + +Y N  + +G   +L L F V
Sbjct: 355 IWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNG-DGTGRGTHLSLFFVV 413

Query: 489 CSGENDAILEWPVENRQVIITILDQ 513
             G NDA+L WP  N++V + +LDQ
Sbjct: 414 MKGPNDALLRWPF-NQKVTLMLLDQ 437


>gi|148886654 polydom [Homo sapiens]
          Length = 3571

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 4/39 (10%)

Query: 672  DPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
            D C P PC N+G+C ++ G   C C SG    YTG+RC+
Sbjct: 1233 DECSPLPCLNNGVCKDLVGEFICECPSG----YTGQRCE 1267



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 674  CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFL 732
            C  NPC+N   CV+     SC+C  G    ++G+RC+  Q  G  L   + G  G + L
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPG----FSGKRCETEQSTGFNLDFEVSGIYGYVML 1441



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 4/37 (10%)

Query: 674  CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQ 710
            C  +PC N GICV+      C C+ G    + G  C+
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKG----FVGLHCE 1305



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 4/36 (11%)

Query: 674  CDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERC 709
            C  NPC N+ +C +  G   C+C  G    + G RC
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPG----FLGTRC 1342


>gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C)
           precursor [Homo sapiens]
          Length = 539

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 9/105 (8%)

Query: 646 GQPSRQKRSVENTGPLED----HNWPQYFRDPCD--PNPCQNDGICVNVKGM-ASCRCIS 698
           G+P R   S EN          HN     R  CD  P+ C N G C  V+ + A CRC +
Sbjct: 344 GEPGRDLASSENGTECRSGFVRHNGS--CRSVCDLFPSYCHNGGQCYLVENIGAFCRCNT 401

Query: 699 GHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQR 743
               ++ G RC+++     V+ + +G  A V+ L F +    +++
Sbjct: 402 QDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKK 446


>gi|75709198 nephronectin [Homo sapiens]
          Length = 565

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 40/167 (23%), Positives = 66/167 (39%), Gaps = 23/167 (13%)

Query: 265 LLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSA 324
           L+  C F+   +CG I+   +D  W        G+       +  G           G A
Sbjct: 418 LVHSCNFDHG-LCGWIREKDNDLHWEPIRDPAGGQYLTVSAAKAPG-----------GKA 465

Query: 325 EEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDD 384
               L   R+++      CL F +K+TG  S  L V+VR+  + G          +  + 
Sbjct: 466 ARLVLPLGRLMHSG--DLCLSFRHKVTGLHSGTLQVFVRKHGAHG-------AALWGRNG 516

Query: 385 DHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPC 431
            H W+   + L+       +F+G K   +  TG I LDD++L +  C
Sbjct: 517 GHGWRQTQITLRGADIKSVVFKGEK--RRGHTGEIGLDDVSLKKGHC 561


>gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]
          Length = 1241

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 674  CDPNP--CQNDGICVNVKGM-ASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVI 730
            CD  P  C NDG C  + G  A CRC  G  ++Y G+ C+       ++G+ I    G++
Sbjct: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLL 1113

Query: 731  FLTFSII 737
             +  +II
Sbjct: 1114 VIFSAII 1120


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,324,849
Number of Sequences: 37866
Number of extensions: 1374888
Number of successful extensions: 3890
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 3203
Number of HSP's gapped (non-prelim): 726
length of query: 746
length of database: 18,247,518
effective HSP length: 110
effective length of query: 636
effective length of database: 14,082,258
effective search space: 8956316088
effective search space used: 8956316088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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