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Search of human proteins with 15149463
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 1092 0.0
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 1058 0.0
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 1026 0.0
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 993 0.0
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 738 0.0
gi|148746195 trichohyalin [Homo sapiens] 106 5e-23
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 105 1e-22
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 102 7e-22
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 101 2e-21
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 99 8e-21
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 97 5e-20
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 94 3e-19
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 93 6e-19
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 93 7e-19
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 92 1e-18
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 91 2e-18
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 90 5e-18
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 89 1e-17
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 89 1e-17
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 87 4e-17
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 85 2e-16
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 84 3e-16
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 83 8e-16
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 82 2e-15
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 81 3e-15
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 81 3e-15
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 81 3e-15
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 80 4e-15
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 79 1e-14
gi|221219020 NYD-SP11 protein [Homo sapiens] 78 2e-14
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 1092 bits (2823), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MLGGSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV 60
MLGGSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV
Sbjct: 1 MLGGSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV 60
Query: 61 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT 120
EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT
Sbjct: 61 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT 120
Query: 121 DASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE 180
DASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE
Sbjct: 121 DASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE 180
Query: 181 DKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK 240
DKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK
Sbjct: 181 DKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK 240
Query: 241 EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 300
EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR
Sbjct: 241 EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 300
Query: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 360
LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL
Sbjct: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 360
Query: 361 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 420
REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK
Sbjct: 361 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 420
Query: 421 SVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSM 480
SVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSM
Sbjct: 421 SVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSM 480
Query: 481 WEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSK 540
WEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSK
Sbjct: 481 WEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSK 540
Query: 541 RNLWEKQSVDKVTSPTKV 558
RNLWEKQSVDKVTSPTKV
Sbjct: 541 RNLWEKQSVDKVTSPTKV 558
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 1058 bits (2736), Expect = 0.0
Identities = 540/541 (99%), Positives = 541/541 (100%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
+IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT
Sbjct: 24 RIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 83
Query: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 257
GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK
Sbjct: 204 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 263
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 317
SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE
Sbjct: 264 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 323
Query: 318 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 377
KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR
Sbjct: 324 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 383
Query: 378 AEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIV 437
AEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIV
Sbjct: 384 AEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIV 443
Query: 438 SKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 497
SKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN
Sbjct: 444 SKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 503
Query: 498 KETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTK 557
KETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTK
Sbjct: 504 KETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTK 563
Query: 558 V 558
V
Sbjct: 564 V 564
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/262 (21%), Positives = 117/262 (44%), Gaps = 21/262 (8%)
Query: 144 EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE--EEKPKRGSIG--- 198
E + E R+++ E E +YQ+ND D EE +E + + +E +K + S+G
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRND-DDEEEAARERRRRARQERLRQKQEEESLGQVT 63
Query: 199 -------ENQGEEKGTKVQAKREKLQ-EDKPTF-----KKEEIKDEKIKKDKEPKEEV-K 244
+N ++ K +++ +D+ F ++EE + +++++ E ++E
Sbjct: 64 DQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDP 123
Query: 245 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL 304
+ D + QN + E + SR +T+ + Q + EE
Sbjct: 124 TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN 183
Query: 305 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEE 364
++ E E EE EK K+ E+ K + +R K+ E++ +K+E D K+++++
Sbjct: 184 KKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 243
Query: 365 E-KRRLKEEIERRRAEAAEKRQ 385
E K +K ++R++ K Q
Sbjct: 244 EPKEEVKSFMDRKKGFTEVKSQ 265
Score = 33.5 bits (75), Expect = 0.53
Identities = 36/177 (20%), Positives = 77/177 (43%), Gaps = 39/177 (22%)
Query: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR-EERRKVLEEEEQRRKQEEADRK 359
+++ RRR E +QK++E LE E + +R ++ + E +RR ++E R+
Sbjct: 1 MDDFERRR--------ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQ 52
Query: 360 LREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLN 419
+EEE ++ +++E + +P++ T + ++ ++ A FL
Sbjct: 53 KQEEESLGQVTDQVE------VNAQNSVPDEEAKT--------TTTNTQVEGDDEAAFLE 98
Query: 420 KSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRN 476
+ ++ + R ++ A+E K PT AS L +P+ ++N
Sbjct: 99 RLARRE---------------ERRQKRLQEALERQKEFDPTITDAS-LSLPSRRMQN 139
Score = 30.8 bits (68), Expect = 3.4
Identities = 39/166 (23%), Positives = 67/166 (40%), Gaps = 27/166 (16%)
Query: 299 KRLEELRRRRGETESEEFEKL---KQKQQEAALELEELKKKREERRKVLEEEEQ-----R 350
+R ELRR++ E E E++ + E E ++ R+ER + +EEE
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 351 RKQEEADRKLREEEEK-RRLKEEIE--------RRRAEAAEKRQKMPEDGLSDDKKPFKC 401
+ + A + +EE K ++E R A E+RQK ++ L K+
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPT 124
Query: 402 FTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQY 447
T SL ++ +Q + T + K +SR E+Y
Sbjct: 125 ITDASLSLP--------SRRMQNDTAENETTEKE--EKSESRQERY 160
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 1026 bits (2653), Expect = 0.0
Identities = 532/558 (95%), Positives = 532/558 (95%), Gaps = 26/558 (4%)
Query: 1 MLGGSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV 60
MLGGSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV
Sbjct: 1 MLGGSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV 60
Query: 61 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT 120
EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT
Sbjct: 61 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT 120
Query: 121 DASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE 180
DASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE
Sbjct: 121 DASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE 180
Query: 181 DKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK 240
DKEKEEEEEEKPKRGSIGENQ IKDEKIKKDKEPK
Sbjct: 181 DKEKEEEEEEKPKRGSIGENQ--------------------------IKDEKIKKDKEPK 214
Query: 241 EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 300
EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR
Sbjct: 215 EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 274
Query: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 360
LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL
Sbjct: 275 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 334
Query: 361 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 420
REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK
Sbjct: 335 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 394
Query: 421 SVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSM 480
SVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSM
Sbjct: 395 SVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSM 454
Query: 481 WEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSK 540
WEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSK
Sbjct: 455 WEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSK 514
Query: 541 RNLWEKQSVDKVTSPTKV 558
RNLWEKQSVDKVTSPTKV
Sbjct: 515 RNLWEKQSVDKVTSPTKV 532
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 993 bits (2566), Expect = 0.0
Identities = 514/541 (95%), Positives = 515/541 (95%), Gaps = 26/541 (4%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
+IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT
Sbjct: 24 RIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 83
Query: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 257
GENQ IKDEKIKKDKEPKEEVKSFMDRKKGFTEVK
Sbjct: 204 GENQ--------------------------IKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 237
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 317
SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE
Sbjct: 238 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 297
Query: 318 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 377
KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR
Sbjct: 298 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 357
Query: 378 AEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIV 437
AEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIV
Sbjct: 358 AEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIV 417
Query: 438 SKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 497
SKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN
Sbjct: 418 SKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 477
Query: 498 KETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTK 557
KETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTK
Sbjct: 478 KETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTK 537
Query: 558 V 558
V
Sbjct: 538 V 538
Score = 37.4 bits (85), Expect = 0.037
Identities = 33/147 (22%), Positives = 66/147 (44%), Gaps = 8/147 (5%)
Query: 330 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 389
+++ +++RE RR+ + EE R + E + +++E+ +E RRRA RQK E
Sbjct: 1 MDDFERRRELRRQ--KREEMRLEAERIAYQRNDDDEEEAARE--RRRRARQERLRQKQEE 56
Query: 390 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTS 449
+ L + + +E A+ + Q ++ + + + R ++
Sbjct: 57 ESLGQVTDQVEV---NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQE 113
Query: 450 AIEGTKSAKPTKPAASDLPVPAEGVRN 476
A+E K PT AS L +P+ ++N
Sbjct: 114 ALERQKEFDPTITDAS-LSLPSRRMQN 139
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 738 bits (1906), Expect = 0.0
Identities = 402/553 (72%), Positives = 434/553 (78%), Gaps = 37/553 (6%)
Query: 29 EEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA 88
E+ E + RA ER R + EE ++++ + DE A+ +E +++A
Sbjct: 255 EKMEEEDKERAEAERARLEAEER------ERIKAEQDKKIADERAR-------IEAEEKA 301
Query: 89 AFLERLARREERRQ------KRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
A ER R E R+ KR E +R KE + + + + E
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKE 361
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENK---KEDKEKEEEEEEKPKRGSIGE 199
+E+++ ++R EE E QK + + EE K +E K K E+ E+K + + E
Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKRN-KQLEEKKHAMQETKIKGEKVEQKIEGKWVNE 420
Query: 200 N--------------QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 245
QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS
Sbjct: 421 KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 480
Query: 246 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 305
FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR
Sbjct: 481 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 540
Query: 306 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 365
RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE
Sbjct: 541 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 600
Query: 366 KRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS 425
KRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS
Sbjct: 601 KRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS 660
Query: 426 SGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGN 485
SGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGN
Sbjct: 661 SGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGN 720
Query: 486 VFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 545
VFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE
Sbjct: 721 VFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 780
Query: 546 KQSVDKVTSPTKV 558
KQSVDKVTSPTKV
Sbjct: 781 KQSVDKVTSPTKV 793
Score = 419 bits (1076), Expect = e-117
Identities = 269/532 (50%), Positives = 334/532 (62%), Gaps = 28/532 (5%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
+IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT
Sbjct: 24 RIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 83
Query: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203
Query: 198 GENQGEEKGTKVQAKREKLQEDK--PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 255
GENQ E V+ K + QE+ + K +I E+ K+++E +E+ + + E
Sbjct: 204 GENQVE---VMVEEKTTESQEETVVMSLKNGQISSEEPKQEEE-REQGSDEISHHEKMEE 259
Query: 256 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 315
+ E +L+ E R +A D K A+ ++EA ++ R R E+EE
Sbjct: 260 EDKERAEAERARLEAEE----RERIKAEQDKKIADERARIEAEEKAAAQERER--REAEE 313
Query: 316 FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE---ADRKLREEEEKRRLKEE 372
E+++++++ AA E + +K+ EE+R EE QR K+EE A+ + R +EE++R EE
Sbjct: 314 RERMREEEKRAAEERQRIKE--EEKRAA--EERQRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 373 IERRRAEAAEK---RQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVK 429
+R RAE EK ++ L + K + KG K+E++ E K V + +
Sbjct: 370 RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE--KVEQKIE--GKWVNEKKAQE 425
Query: 430 STHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSS 489
Q A++ K E+ T + + KP + E ++ K E+ F
Sbjct: 426 DKLQTAVLKKQGE--EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMD 483
Query: 490 PTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKR 541
T K G + + E P G S K ++ P + KR
Sbjct: 484 RKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 535
Score = 55.5 bits (132), Expect = 1e-07
Identities = 74/366 (20%), Positives = 151/366 (41%), Gaps = 44/366 (12%)
Query: 144 EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE--EEKPKRGSIG--- 198
E + E R+++ E E +YQ+ND D EE +E + + +E +K + S+G
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRND-DDEEEAARERRRRARQERLRQKQEEESLGQVT 63
Query: 199 -------ENQGEEKGTKVQAKREKLQ-EDKPTF-----KKEEIKDEKIKKDKEPKEEV-K 244
+N ++ K +++ +D+ F ++EE + +++++ E ++E
Sbjct: 64 DQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDP 123
Query: 245 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL 304
+ D + QN + E + SR +T+ + Q + EE
Sbjct: 124 TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN 183
Query: 305 RRRRGETESEEFEKLKQ---KQQEAALELEELKKKREERRKVL--------------EEE 347
++ E E EE EK K+ + + + +EE + +E V+ EEE
Sbjct: 184 KKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEE 243
Query: 348 EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPF----KCFT 403
++ E + + EEE+K R + E R AE E+ + + ++D++ K
Sbjct: 244 REQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA 303
Query: 404 PKGSSLKIEER---AEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 460
+ + EER E ++ ++ +K + A + + E+ +A E + +
Sbjct: 304 QERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE 363
Query: 461 KPAASD 466
K AA +
Sbjct: 364 KRAAEE 369
Score = 33.5 bits (75), Expect = 0.53
Identities = 36/177 (20%), Positives = 77/177 (43%), Gaps = 39/177 (22%)
Query: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR-EERRKVLEEEEQRRKQEEADRK 359
+++ RRR E +QK++E LE E + +R ++ + E +RR ++E R+
Sbjct: 1 MDDFERRR--------ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQ 52
Query: 360 LREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLN 419
+EEE ++ +++E + +P++ T + ++ ++ A FL
Sbjct: 53 KQEEESLGQVTDQVE------VNAQNSVPDEEAKT--------TTTNTQVEGDDEAAFLE 98
Query: 420 KSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRN 476
+ ++ + R ++ A+E K PT AS L +P+ ++N
Sbjct: 99 RLARRE---------------ERRQKRLQEALERQKEFDPTITDAS-LSLPSRRMQN 139
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 106 bits (265), Expect = 5e-23
Identities = 99/467 (21%), Positives = 209/467 (44%), Gaps = 50/467 (10%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
Q+ + E++ RE++ R+++LR++QEE Q+ + E + E + Q
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Query: 82 VEGDDEAAFLERLARREERR---QKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN 138
+ + + ++L R ++ R Q R ++ L R+++ R +
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL--------------RREQQLRRE 422
Query: 139 ETTEKEEKSESRQERYEIEETETVTKSYQ--KNDWRDAEENKKEDKEKEEEEEEKPKRGS 196
+ +E++ E ++++E E E K Q + DW ++E+ E+ E+E K +
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWL----KREEETERHEQERRKQQLKR 478
Query: 197 IGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
E + E+ K++ + + Q+++ + ++E+ ++ + +EE + R + ++
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316
+ + E LK E R +E E + + KR EE R++R + E E
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQE-ERRDQLLKREEERRQQRLKREQE-- 595
Query: 317 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERR 376
E+L+Q+ + +E E +++RE+R K E EE+RR+Q L+ EE++ R ++++ R
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ-----LLKSEEQEERRQQQLRRE 650
Query: 377 RAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAI 436
+ E E+R K E+ ++E+R + ++ ++ + Q
Sbjct: 651 QQERREQRLKREEE-----------------EERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 437 VSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEK 483
+I SR+ ++ +E A+ +K P EG R + EK
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSK--VYSRPRKQEGQRRRQEQEEK 738
Score = 102 bits (255), Expect = 7e-22
Identities = 108/457 (23%), Positives = 215/457 (47%), Gaps = 51/457 (11%)
Query: 23 RNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
R EE+ + RR RQ+R+ Q +EEE + + V + + +EE + Q
Sbjct: 219 RRKGREEKQQQ---RRERQDRVFQ-EEEEKEWRKRETVLRKEEEKLQEEEPQ-----RQR 269
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
E +E L +L R+E RR+++ +E +++ + + RR Q + + E
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL---------RRKQEEERREQQEE 320
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDW---RDAEENKKEDKEKEEEEEEKPKRGSIGE 199
+ E+ E R+++ E E + + ++ + R+ EE ++E + + E+EEE+ ++ E
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 200 NQ---GEEKGTKVQAKREKLQEDKPTFKKEE--IKDEKIKKDKEPKEEVKSFMDRKKGFT 254
Q ++ + Q +RE+ + ++E+ ++++++++++ + E + +K
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 255 EVKSQ----NGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR--- 307
E + Q E LK E T R K + + E +LEE RR
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 308 -------RGETESEEFEKLKQKQQEAALEL-----EELKKKREERRKVL--EEEEQRRKQ 353
R E E ++LK++++E L+ ++L++++EERR+ L EEE+R +Q
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 354 EEADRKLREEEEKRR---LKEEIERRRAEAAEKRQKMPEDGLS-DDKKPFKCFTPKGSSL 409
E +++L+ E+E+RR LK E ERR+ ++++ E L ++ + + + L
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 410 KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQ 446
K EE E + + KS + Q + + R EQ
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Score = 101 bits (252), Expect = 2e-21
Identities = 85/368 (23%), Positives = 175/368 (47%), Gaps = 38/368 (10%)
Query: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 85
++EE+ R R+RR R++ L+ +EEE L + + Q E D
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQL------------------QRRERAQQLQEEED 854
Query: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 145
ER +E+RR ++ + LE +++ A +L + + ++++
Sbjct: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL----------QEQLRKEQQ 904
Query: 146 KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEK 205
+ +E + EE E + Q+ +R+ E+ ++E+++ EE EK +R + K
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE--RERQYRK 962
Query: 206 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM--DRKKGFTEVKSQNGEF 263
K+Q K E+L ++P ++ + +++K ++++E ++E + + +R+K + +
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 264 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGET-ESEEFEKLKQK 322
+ E + + +E + + E + E+L ET +E E+ +K
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 323 QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK----LREEEEKRRLKEEIERRRA 378
++E E E+L ++ E+R+ E E Q R++EE ++ LREE EKRR ++E+ER+
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR-RQELERQYR 1141
Query: 379 EAAEKRQK 386
E E +Q+
Sbjct: 1142 EEEEVQQE 1149
Score = 99.4 bits (246), Expect = 8e-21
Identities = 101/406 (24%), Positives = 182/406 (44%), Gaps = 57/406 (14%)
Query: 27 DEEEAARER-RRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 85
+EE+ RE +R RQER RQ +EEE L Q +Q+ + E+ + Q +
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER-----EKRRRQELERQYREE 1143
Query: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 145
+E E REE +KR ++ LERQ + + L + E E +EE
Sbjct: 1144 EEVQQEEEQLLREEP-EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 146 KSESRQERYE----------------------IEETETVTKSYQKNDWRDAEENKKEDK- 182
+ RQ+R + + + + K + +R E+++ D+
Sbjct: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
Query: 183 ----------EKEEEEEEKPKR------GSIGENQGEEKGTKVQAKR--EKLQEDKPTFK 224
E++E + E+ +R E + E+ + +AKR K QE+K +
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 225 KE-EIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTEN-----TFSRP 278
+E E K + + D++ +EE + +R++ + ++ +F +L+H E +
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR 1382
Query: 279 GGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 338
R + K + Q+ +R ++LR+ R EE ++L +++++ EE + +R+
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 339 ER-RKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 383
ER RK LEEE+Q R +E RK REEE+ + +EE + R E K
Sbjct: 1443 ERERKFLEEEQQLR--QERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Score = 97.8 bits (242), Expect = 2e-20
Identities = 100/422 (23%), Positives = 203/422 (48%), Gaps = 59/422 (13%)
Query: 26 DDEEEAARERRRRARQER--LRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVE 83
++E++ +ER R+ R+E L++++E++ Q D+ + + + +E ++
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 84 GDD-EAAFLE--RLARREERRQKRLQEA--LERQKEFDPTITDASLSLPSRRMQNDTAEN 138
+ E FLE + R++R++K LQE L RQ+ D R+ + + E
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD-----RKFREE--EQ 1562
Query: 139 ETTEKEEKSESRQER---YEIEETETVTKSYQKNDWRDAEENKKEDKEKE--EEEEEKPK 193
E+EE+ SRQER + +EE + + ++ D ++ ++++ +++ +E + K +
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
Query: 194 RGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF 253
+ EE+ Q + K E++P +++E ++++++ D+ DRK
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE-REQQLRHDR----------DRKFRE 1671
Query: 254 TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES 313
E Q GE +L+ E D K E Q+ +R + + +
Sbjct: 1672 EEQLLQEGE--EQQLRRQER-----------DRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 314 EEFEKLKQKQQEAALELEELKKKREER-RKVLEEE-------EQRRKQEEADRKLREEEE 365
+E E+ +++++ E E+ + +R+ER RK+LEEE EQ+ +++E DRK REEE+
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 366 KRRLKEEIERRRAEAAEK-------RQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFL 418
R+ +EE + R E+ K RQ+ E L ++ K + + L++EE+ + L
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK-YRWEEEQLQLEEQEQRL 1837
Query: 419 NK 420
+
Sbjct: 1838 RQ 1839
Score = 97.4 bits (241), Expect = 3e-20
Identities = 92/372 (24%), Positives = 184/372 (49%), Gaps = 21/372 (5%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ---VEG 84
E+E RE+R + ++E R +Q S Q+ + E + + EE K + ++
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 85 DDEAAFLERLARREERRQKRL----QEALERQKEFDPTITDASLSLPSRRMQNDTAENET 140
+ E + L R EERRQ+RL +E LE++ + + +R++ + E E
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 141 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 200
++ KSE ++ER + + + ++ R+ EE + E + K E EEE+ ++ + E
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ-ELAEE 688
Query: 201 QGEEKGTKVQAKREKLQ---EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 257
+ E+ +++++ K Q E + ++ ++ K++ + + + + R++ +E++
Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE-SELQ 747
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 317
Q E H+ + E + + K G ++ A L E R R + +EE +
Sbjct: 748 WQEEE-RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER--QLRAEERQ 804
Query: 318 KLKQKQQEAALELEELKKKREERRK---VLEEEEQRRKQEEADRKLREEEEKRRLKEEIE 374
+ +Q+ E E+ +++R ER K LEEEEQ +++E A ++L+EEE+ L+E+ E
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA-QQLQEEEDG--LQEDQE 861
Query: 375 RRRAEAAEKRQK 386
RRR++ + QK
Sbjct: 862 RRRSQEQRRDQK 873
Score = 96.7 bits (239), Expect = 5e-20
Identities = 102/408 (25%), Positives = 189/408 (46%), Gaps = 43/408 (10%)
Query: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
L Q Q +++E+ +ER R+ R+E Q+Q+ + + DQ P++E
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 76 TTTNTQVEGDDEAAF--LERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN 133
+G + F LE R+ + Q+ LQ L Q+E D + +R ++
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD---REQERRRWQQRDRH 1292
Query: 134 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENK-KEDKEKEEEEEEKP 192
E + +E+K R++R EE + + + ++ R + K +E+++ +E EE+P
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 193 KRGS-------IGENQGEEKGTKVQAKREKL--QEDKPTFKKEE------IKDEKIKKDK 237
R E + +E+G K + ++L QE + F KEE +++++++D+
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 238 EPK----EEVKSFMDRKKGFTEVKSQ------NGEFM--THKLKHTENTFSRPGGRASVD 285
+ K E+ S +R + F E + Q +F+ +L+ + R + +
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 286 TKEAEGAPQVEAGKRLEE---LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRK 342
+E + Q K LEE LRR+ + + E E Q+ + LE E+ +++ +RK
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 343 VLEEEEQRRKQE-------EADRKLREEEEKRRLKEEIERRRAEAAEK 383
L+EE+Q R+QE + DRK REEE+ R+ +EE + R E K
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Score = 96.3 bits (238), Expect = 7e-20
Identities = 95/431 (22%), Positives = 196/431 (45%), Gaps = 40/431 (9%)
Query: 27 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS--------VPDEEAKTTTT 78
+EE+ RE + + RQER RQ +EEE L + + ++ P++E
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Query: 79 NTQVEGDDEAAF--LERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA 136
+G + F LE R+ + Q+ LQ L Q+E D + +R ++
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD---REQERRRWQQRDRHFPE 1295
Query: 137 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENK-KEDKEKEEEEEEKPKRG 195
E + +E+K R++R EE + + + ++ R + K +E+++ +E EE+P R
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 196 SIGENQGEEKGTKVQAKREKLQEDKPTFKKEE-----IKDEKIKKDKEPKEEVKSFMDRK 250
+ + E+ + Q + K E++ +++E +K+E+ + +E +++++ DRK
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 251 KGFTEVKSQ-NGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL----- 304
F E + Q + + K + E R +E + + R EE
Sbjct: 1416 --FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 305 ------RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE---- 354
R+ R EE ++L++++++ +EL+ + ER K LEEE+Q +Q+
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER-KFLEEEQQLHRQQRQRK 1532
Query: 355 --EADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIE 412
+ +++LR +E ++ +++ +R+ E + RQ+ E LS ++ K + + E
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 413 ERAEFLNKSVQ 423
+ +F+ Q
Sbjct: 1593 QERKFMEDEQQ 1603
Score = 96.3 bits (238), Expect = 7e-20
Identities = 96/396 (24%), Positives = 185/396 (46%), Gaps = 35/396 (8%)
Query: 28 EEEAAR--ERRRRARQERLRQKQEEESLGQVTDQV---EVNAQNSVPDEEAKTTTTNTQV 82
EE+ R ER R+ R+E LR +++ + ++ E + +++ + Q+
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 83 EGDDEAAFLE---RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENE 139
D + F E +L+R+E R+ R +E R++E + + L R + E +
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 140 TT-EKEEKSESRQERYE--IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 196
E+EE+ RQER +EE + + + + +R+ E +E + K EEE++ R
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 197 IGEN-QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 255
EE+ + Q + ++ ++D+ +EE E++++++E ++ + DRK E
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREE---EQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 256 VKSQNGEFMTHKLKHTENTFSRPGGRASV----DTKEAEGAPQVEAGKRLEELRRRRGET 311
K + E K E R G+ + D K E ++ + + R+ R
Sbjct: 1586 QKVRRQE-QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 312 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 371
EE +L+++++E L + +K REE + + E EEQ+ +++E DRK REEE++ R +E
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 372 ---------------EIERRRAEAAEKRQKMPEDGL 392
E+ER+ E + RQ+ ++ L
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Score = 95.9 bits (237), Expect = 9e-20
Identities = 95/438 (21%), Positives = 208/438 (47%), Gaps = 38/438 (8%)
Query: 21 YQRNDD---DEEEAARERRRRAR-QERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTT 76
Y++ D+ +EE+ RE R + R QER RQ +EEE L Q +Q+ + + +E +
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Query: 77 TTNTQVEGDDEAAFL--ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQND 134
+ +E L E RR + R+++ +E E Q+E + + + + ++
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 135 TAENETTEKEEKSESRQE-----RYEIEETETVTKSYQKND---WRDAEENKKED----- 181
E E ++EE+ R+E R E+E + Q+ + R+ +E ++++
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 182 KEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKK-------EEIKDEKIK 234
+E+EE + +K K+ E+Q + + + ++E D + K +++D ++
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL- 1258
Query: 235 KDKEPKEEVKSFM-DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAP 293
+D++ +++++ + ++++ E + + + E A ++++
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318
Query: 294 QVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKK--------REERRKVLE 345
Q+ +R E+ RR+ + + E E+L Q+++E L +E +K +E+ RK LE
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 346 EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPK 405
EE++ R+QE +RK +EE++ R +E E++ + +++ + E LS ++ K +
Sbjct: 1379 EEQRLRRQER-ERKFLKEEQQLRCQER-EQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436
Query: 406 GSSLKIEERAEFLNKSVQ 423
+ E +FL + Q
Sbjct: 1437 QQVRRQERERKFLEEEQQ 1454
Score = 94.7 bits (234), Expect = 2e-19
Identities = 87/388 (22%), Positives = 189/388 (48%), Gaps = 47/388 (12%)
Query: 27 DEEEAAR----ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
DEE+ R E RR+ R+E+ +Q++E + D+V +EE K V
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQ------DRV-------FQEEEEKEWRKRETV 252
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
+E E+L E +RQ+ LQE E+ ++ + ++ Q E +
Sbjct: 253 LRKEE----EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 143 K--EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 200
K EE+ E ++ER E +E + ++ R +E ++E + + E+EEE+ ++ +
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ-QLRRE 367
Query: 201 QGEEKGTKVQAKREKLQEDKPTFKKEEIK-DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 259
Q EE+ + + ++L+ ++ ++++++ +++++++++ + E + +++ + +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 260 NGEFMTHKLKHTENTFSRPGGRASVDT----KEAEGAPQVEAGKRLEELRRRRGETESEE 315
E H+ KH + + R + K E + E +R ++L+R + E E
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 316 FEKLKQKQQEAALELEE--LKKKREERRKVLEEEEQRRKQEEADR---KLREEEEKRRLK 370
+ KL+++++ E E L++++EERR E++ ++QEE +R +LR E++ RR +
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERR-----EQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 371 EE--------IERRRAEAAEKRQKMPED 390
EE E +R E + Q++ +
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKRE 570
Score = 94.0 bits (232), Expect = 3e-19
Identities = 87/405 (21%), Positives = 190/405 (46%), Gaps = 51/405 (12%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLR---------QKQE----------EESLGQVTD 58
Q ++ D EE +RRR+ RQE+ R +KQE +E L +
Sbjct: 119 QRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQ 178
Query: 59 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAF-------LERLARREERRQKRLQE--AL 109
+ + + +E+ ++ + E DE L R R E+++Q+R ++
Sbjct: 179 EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
Query: 110 ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ-ERYEIEETETVTKSYQK 168
+ ++E + + L ++Q + + + +EE+ + R+ ER E+ + Q+
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 169 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEI 228
R+ + +K+++E+ E++EE+ ++ E Q E + +++ ++E+ +E + ++EE
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 229 KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 288
+ E+ + ++ +E + + R++ +L+ + R +
Sbjct: 359 RREQQLRREQEEERREQQLRREQ---------------QLRREQQLRREQQLRREQQLRR 403
Query: 289 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 348
+ + + +R ++LRR + +E E+ +QK ++ E + LK+++EERR L+ EE
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE-QRLKREQEERRDWLKREE 462
Query: 349 QRRKQEEADRK---LREEEEKRR---LKEEIERRRAEAAEKRQKM 387
+ + E+ RK R++EE+RR LK E E RR + + Q++
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
Score = 94.0 bits (232), Expect = 3e-19
Identities = 92/428 (21%), Positives = 194/428 (45%), Gaps = 59/428 (13%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ-VTDQVEVNAQNSVPDEEAKTT 76
Q+ ++ + E++ RE+ R+++LR++QEEE Q + + ++ + + E+
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ--L 395
Query: 77 TTNTQVEGDDEAAFLERLAR----REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQ 132
Q+ + + ++L R R E++ +R QE +++ + + L +
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 133 NDTAENETTEKEEKSESRQE--RYEIEETETVTKSYQKNDWRDAEENKKED--KEKEEEE 188
+ E TE+ E+ +Q+ R + EE ++ + R+ +E +++ +E+EE
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 189 EEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK-------DEKIKKDKEPKE 241
E++ KR E + ++ Q +RE+ + + K+EE K ++++K+++E +
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 242 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTE----NTFSRPGGRASVDTKEAEGAPQVEA 297
+ + ++ +K + E + +LK E R R + E E Q+
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 298 GKRLEELRRR--RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLE--EEEQR--- 350
+ EE R++ R E + ++LK++++E LE + LK++ EE R+ E EEEQ
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLE-QRLKREHEEERREQELAEEEQEQAR 694
Query: 351 -----------------------------RKQEEADRKLREEEEKRRLKEEIERRRAEAA 381
RKQE R+ +EE++RR + E++ + E A
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 382 EKRQKMPE 389
++Q+ E
Sbjct: 755 HRQQQEEE 762
Score = 93.6 bits (231), Expect = 4e-19
Identities = 95/372 (25%), Positives = 180/372 (48%), Gaps = 40/372 (10%)
Query: 35 RRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERL 94
+RRR QE R+++E E Q ++ Q +E+ + T Q E E
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQE---EEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 95 AR---REER-RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT--EKEEKSE 148
AR RE+R RQ R +E +R++ F P + RR Q E E E+EE+ +
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKE----QRRRQRREREKELQFLEEEEQLQ 841
Query: 149 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTK 208
R+ +++E E + Q+ R ++E +++ K + + EEE+ +R
Sbjct: 842 RRERAQQLQEEEDGLQEDQER--RRSQEQRRDQKWRWQLEEERKRR--------RHTLYA 891
Query: 209 VQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 268
A +E+L++++ ++EE + ++ +++K ++E +R+ E Q E + +
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQE----QERQYREEEQLQQEEEQLLREE 947
Query: 269 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL 328
+ R R K+ + + G+ E+ RR+ E + E E+L+Q++++
Sbjct: 948 REKRRRQERE--RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL-- 1003
Query: 329 ELEELKKKREERRKVLEEEEQRRK---QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 385
L+++RE+RR+ E + R+K Q+E ++ LREE EKRRL+E + R E E+ Q
Sbjct: 1004 ----LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE--EELQ 1057
Query: 386 KMPEDGLSDDKK 397
+ E L ++++
Sbjct: 1058 QEEEQLLGEERE 1069
Score = 92.0 bits (227), Expect = 1e-18
Identities = 102/472 (21%), Positives = 198/472 (41%), Gaps = 78/472 (16%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
Q ++E+ ER +R RQER RQ ++++ L Q +Q+ P++ +
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL----LGEEPEKRRRQEREKKY 990
Query: 82 VEGDDEAAFLERLARREE-----------------------------RRQKRLQEALERQ 112
E ++ E+L R E R ++RLQE +
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050
Query: 113 KEFDPTITDASLSLPSRRMQNDTAENETT-EKEEKSESRQERYEIEETETVTKSYQKNDW 171
+E + + L R E E KEE+ + +E+ EE E + ++
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 172 RDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKR------------------ 213
R+ EE ++E+++ EE EK +R + EE+ + + ++
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 214 ---EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH 270
E+LQ+++ +EE + + +++++ +EE + ++K + Q +
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 271 TENTFSRP----GGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-- 324
EN GR + ++ E + Q+ + ++L+ GE + + E+ +++ Q
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDS-QLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Query: 325 ------EAALELEELK-------KKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 371
E LE EE K K +EE++ + EE E++R+++E DRK REEE+ + +E
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 372 EIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 423
E RR E+ +K E+ L ++ K + + E +FL + Q
Sbjct: 1350 EQPLRR---QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Score = 91.7 bits (226), Expect = 2e-18
Identities = 83/374 (22%), Positives = 176/374 (47%), Gaps = 24/374 (6%)
Query: 22 QRNDDDEEEAAR--ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTN 79
QR EE+ R ER ++ RQ+R R+ +EEE L Q ++ +++ Q D + +
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER--DRKFRLEEQK 1587
Query: 80 TQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA--- 136
+ + + + R + Q++L++ +R+ D + R + D
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 137 ENETTEKEEKSES---------RQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE- 186
E ++E+ + R+E ++E E Q+ D + EE ++ +++ E
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 187 ---EEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 243
+EE++ +R + EE+ + + ++E+L+ + ++ +++E+++ ++E ++
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY--RKILEEEQLRPEREEQQLR 1765
Query: 244 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 303
+ DRK E Q E + + ++ F R + + +E + PQ GK E
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKF-REEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 304 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 363
+ + E + + + + +Q A + +K R E +++ +EEEQ+R+QE +RKLREE
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER-ERKLREE 1883
Query: 364 EEKRRLKEEIERRR 377
+R+ KEE R+
Sbjct: 1884 HIRRQQKEEQRHRQ 1897
Score = 89.0 bits (219), Expect = 1e-17
Identities = 92/405 (22%), Positives = 187/405 (46%), Gaps = 35/405 (8%)
Query: 9 GRRSLAALSQIAYQRND-----DDEEEAARERRRRARQERLRQKQEEESLGQVTDQV--- 60
GR+ L ++ Q + ++++ +ER ++ RQ+R R+ +EEE Q++ Q
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ--QLSRQERDR 1430
Query: 61 ---EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLER---LARREER---RQKRLQEALER 111
E Q + E K Q+ + F E L REE+ RQ+R ++ LE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 112 QKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETET--VTKSYQKN 169
+++ D R Q + E++ + RQ ++ EE + + Q+
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 170 DWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK 229
RD + ++E +E EE++ ++ + + EE+ + Q + K ED+ +++E +
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 230 DE-KIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHK--LKHTENTFSRPGGRASVDT 286
+ + ++D++ +E+ + +R++ + ++ +F+ + L+ E R D
Sbjct: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR---DR 1667
Query: 287 KEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEE 346
K E ++ G+ + R+ R EE ++L+++++E EE + +R+E + E
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 347 EEQRRKQEEAD--------RKLREEEEKRRLKEEIERRRAEAAEK 383
EEQ R++ E + RK+ EEE+ R +EE + RR E K
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Score = 87.8 bits (216), Expect = 2e-17
Identities = 77/365 (21%), Positives = 170/365 (46%), Gaps = 43/365 (11%)
Query: 22 QRNDDDEEEAARERRRRARQERLR------QKQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
Q +++ + RE+RRR QER Q++EE+ L + ++ + ++ K
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 135
Q+ G+ E RR + R+K+ +E E Q+E + + + + +
Sbjct: 967 QQKEEQLLGE------EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 136 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 195
+ + ++EE+ R+ER + E ++ +R+ EE ++E+++ EE E +R
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQE------RERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 196 SIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 255
+ +E+ ++Q + E+L ++P ++ + ++ + ++++E ++E + + ++
Sbjct: 1075 ELERQYRKEE--ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 256 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 315
+ ++ +E E + E R E +RRR E E +
Sbjct: 1133 RQELERQY----------------------REEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 316 FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIER 375
E+ + +Q+E L EE +K+R+ER + EEE+ ++Q+ R R+E+++ LK + E
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR-YRDEDQRSDLKWQWEP 1229
Query: 376 RRAEA 380
+ A
Sbjct: 1230 EKENA 1234
Score = 86.7 bits (213), Expect = 5e-17
Identities = 103/421 (24%), Positives = 184/421 (43%), Gaps = 88/421 (20%)
Query: 27 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT----TNTQV 82
D+EE RER + +E R++QE +Q E Q EE + + Q+
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 83 EGDDEAAFLERLARREERR--QKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 140
+ E + L R EE+R Q+R ++ L+R++E D L R Q +
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQE---ERRDQLLKREEERRQ----QRLK 591
Query: 141 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 200
E+EE+ E R +R E+E E + Q+ + EE +++ K EE+EE+ ++ E
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
Query: 201 QGE-EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP--KEEVKSFMDRKKGFTEVK 257
Q E+ K + + E+L++ +EE +++++ ++++ +E +KS + + + E +
Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES---- 313
+ + +SRP R +E +RRR E E
Sbjct: 712 ADARQ---------SKVYSRP---------------------RKQEGQRRRQEQEEKRRR 741
Query: 314 -------EEFEKLKQKQQE-----------AALELEELKKKREERRKVLEEEEQRR---- 351
+E E+ ++QQE A E E ++R R L E+ +R+
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801
Query: 352 -KQEEADRKLREEEEKRR--------------LKEEIERRRAEAAEKRQKMPEDGLSDDK 396
+Q+ R L EEEEK + L+EE + +R E A++ Q+ EDGL +D+
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE-EEDGLQEDQ 860
Query: 397 K 397
+
Sbjct: 861 E 861
Score = 86.3 bits (212), Expect = 7e-17
Identities = 84/311 (27%), Positives = 156/311 (50%), Gaps = 47/311 (15%)
Query: 96 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 155
RR+E Q+R E +RQ E +P RR + E E E EE+SE +QER E
Sbjct: 113 RRQEEDQRRF-EPRDRQLEEEPG--------QRRRQKRQEQERELAEGEEQSE-KQERLE 162
Query: 156 IEETETVTKSY--QKNDWRDAEENKKEDKE---------KEEEEEEKPKRGSIGENQGEE 204
+ + + Q+ +W++ EE + E+++ +E +EE+ +R + E + +
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG 222
Query: 205 KGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM 264
+ K Q +RE+ +D+ F++EE K+ + ++ KEE K + ++ + + Q E
Sbjct: 223 REEKQQQRRER--QDR-VFQEEEEKEWRKRETVLRKEEEK--LQEEEPQRQRELQEEEEQ 277
Query: 265 THKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ 324
KL+ E +E + Q + R E+ RR+ E E E ++ +++QQ
Sbjct: 278 LRKLERQELR------------RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 325 EAALELEE-----LKKKREERRKVL---EEEEQRRKQEEADRKLREEEEKRRLKEEIERR 376
E + EE L++++EERR+ E+EE+RR+Q + R+ EE +++L+ E + R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQ-QLRREQEEERREQQLRREQQLR 384
Query: 377 RAEAAEKRQKM 387
R + + Q++
Sbjct: 385 REQQLRREQQL 395
Score = 84.0 bits (206), Expect = 3e-16
Identities = 95/397 (23%), Positives = 188/397 (47%), Gaps = 40/397 (10%)
Query: 26 DDEEEAARERRRRARQER----LRQKQEEESLGQ--VTDQVEVNAQNSVPDEEAKTTTTN 79
+++EE +++ RR +QER L++++EEE L Q + E + + +EE +
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 80 T---------QVEGDDEAAFLERLAR-REERRQKRLQEALERQKEFDPTITDASLSLPSR 129
Q+E + +A + +R R++ Q+R QE E+++ + + R
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 130 RMQNDTAENETT---EKEEKSESRQERY-------EIEETETVTKSYQKNDWRDA-EENK 178
+ Q + + T + EEKSE ++R E E + + Q+ + R EE +
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 179 KEDKEKEEEEEEKPKRGSIGENQGE--EKGTKVQAKREKLQEDKPTFK-KEEIKDEKIKK 235
KE + ++ E EK + E Q + E+ ++Q + + LQED+ + +E+ +D+K +
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Query: 236 D-KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDT--KEAEGA 292
+E ++ + + K E + + + + + + R + +E E
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 293 PQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK 352
Q E EE +RR + ++ K K+ QQ+ E + L ++ E+RR+ E++ R +
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQK---EEQLLGEEPEKRRRQEREKKYREE 993
Query: 353 ---QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
Q+E ++ LREE EKRR ++E ER+ + E +Q+
Sbjct: 994 EELQQEEEQLLREEREKRR-RQEWERQYRKKDELQQE 1029
Score = 81.6 bits (200), Expect = 2e-15
Identities = 75/367 (20%), Positives = 170/367 (46%), Gaps = 62/367 (16%)
Query: 26 DDEEEAARERRRRARQERL--RQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVE 83
D +E ++RR+ Q R R +Q EE GQ Q + + E
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL-------------AE 150
Query: 84 GDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEK 143
G++++ ERL +R+ RQ+R +E +++E+ R + E + K
Sbjct: 151 GEEQSEKQERLEQRD--RQRRDEELWRQRQEWQ-----------EREERRAEEEQLQSCK 197
Query: 144 EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGE 203
++E + ++ E + + + + + +++D+ +EEEE+ +
Sbjct: 198 GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK----------EWR 247
Query: 204 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEF 263
++ T ++ + EKLQE++P ++ E+++E+ + K ++E++ + Q E
Sbjct: 248 KRETVLRKEEEKLQEEEPQ-RQRELQEEEEQLRKLERQELRR-----------ERQEEEQ 295
Query: 264 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ 323
+L+ + + +E E Q E + +E R ++ E ++ + ++++
Sbjct: 296 QQQRLRREQQLRRK---------QEEERREQQEERREQQERREQQEERREQQLRREQEER 346
Query: 324 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR---LKEEIERRRAEA 380
+E L E+ +++RE++ + +EEE+R +Q +++LR E++ RR L+ E + RR +
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 381 AEKRQKM 387
+ Q++
Sbjct: 407 LRREQQL 413
Score = 79.7 bits (195), Expect = 6e-15
Identities = 74/354 (20%), Positives = 165/354 (46%), Gaps = 18/354 (5%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE-VNAQNSVPDEEAKTT 76
Q+ +R + R+R+ R ++++R++++E + Q+ Q + E +
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 77 TTNTQVEGDDEAAFLERLARREERRQKRLQEA--LERQKEFDPTITDASLSLPSRRMQND 134
+ Q+ + E E+ R+ER +K L+E L RQ+ D + +
Sbjct: 1622 REDEQLLQERE----EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF----REEE 1673
Query: 135 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 194
E E++ + + R ++ EE + + ++ ++ ++ ++++ E++ EEE+
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ--- 1730
Query: 195 GSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT 254
+ + +E+ + + R+ L+E++ ++EE + + ++D++ +EE + +R++
Sbjct: 1731 --LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Query: 255 EVKSQNGEFMTHKL--KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETE 312
+ + +F + + E RP R E E E +RL + R R+ E
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848
Query: 313 SEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK 366
+ + K +++E L EE +K+R+ER + L EE RR+Q+E R + E K
Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
Score = 53.1 bits (126), Expect = 6e-07
Identities = 44/181 (24%), Positives = 89/181 (49%), Gaps = 19/181 (10%)
Query: 231 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 290
E + +D+ +E+ + F R + +++ + G+ K + E + +++ E
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDR---QLEEEPGQRRRQKRQEQERELAE----GEEQSEKQE 159
Query: 291 GAPQVEAGKRLEELRRRRGE--------TESEEFEKLKQKQQEAALELEELKKKR--EER 340
Q + +R EEL R+R E E E+ + K + E + E+L+++ E R
Sbjct: 160 RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELR 219
Query: 341 RKVLEEEEQRRKQEEADRKLREEEEKR-RLKEEIERRRAEAAEKRQKMPEDGLSDDKKPF 399
RK EE++Q+R+ E DR +EEEEK R +E + R+ E ++ + + L ++++
Sbjct: 220 RKGREEKQQQRR-ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 400 K 400
+
Sbjct: 279 R 279
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/242 (19%), Positives = 103/242 (42%), Gaps = 37/242 (15%)
Query: 23 RNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
R + E + +E ++ RQE R+ +EEE L Q T+Q ++
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL-------------------- 1740
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
RR+ER +K L+E R + + + R + E E +
Sbjct: 1741 -------------RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
+ R+ R E + + + + RD + +E++ + EE+E++ ++ + +
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 203 EEKGTKVQAKREKLQE--DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 260
EE+ + R + QE + K+ + ++ K++++ +++ + R+ G E+KSQ
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVG--EIKSQE 1905
Query: 261 GE 262
G+
Sbjct: 1906 GK 1907
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/155 (25%), Positives = 77/155 (49%), Gaps = 14/155 (9%)
Query: 304 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE---EADRKL 360
L+ RR E + FE + +Q E +K++E+ R++ E EEQ KQE + DR+
Sbjct: 110 LQDRRQEEDQRRFEP-RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
Query: 361 REEEEKRRLKE--EIERRRAEAAE-------KRQKMPEDGLSDDKKPFKCFTPKGSSLKI 411
R+EE R+ +E E E RRAE + + ++ P++ ++ + KG K
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE-LRRKGREEKQ 227
Query: 412 EERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQ 446
++R E ++ Q+ + + ++ K + +L++
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 22/129 (17%)
Query: 281 RASVDTKEA--EGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 338
RA D KE+ + Q E +R E R + E E ++ +QK+QE EL E +++ E
Sbjct: 100 RARCDGKESLLQDRRQEEDQRRFEPRDR---QLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 339 ERRKVLEEEEQ-------RRKQEEADRKLREEEEKR----------RLKEEIERRRAEAA 381
++ ++ + + Q R++QE +R+ R EE++ +E + RR E
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 382 EKRQKMPED 390
E R+K E+
Sbjct: 217 ELRRKGREE 225
Score = 29.3 bits (64), Expect = 10.0
Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Query: 327 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
A L+E K+ R + ++ L ++ R+QEE R+ E R+L+EE +RR + +++++
Sbjct: 92 ATGLDEEKRARCDGKESLLQD---RRQEEDQRRF--EPRDRQLEEEPGQRRRQKRQEQER 146
Query: 387 MPEDGLSDDKK 397
+G +K
Sbjct: 147 ELAEGEEQSEK 157
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 105 bits (261), Expect = 1e-22
Identities = 97/406 (23%), Positives = 196/406 (48%), Gaps = 21/406 (5%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEE-ESLGQVTDQVE-VNAQNSVPDEEAKTTTTN 79
Q + +++ +E R + ERLR+K+E ++ +QVE + + + ++E KT
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 443
Query: 80 TQVEGDDEAAFLERLARREERRQKRLQEALERQKE--FDPTITDASLSLPSRRMQNDTAE 137
+++ ++ E+ R EE + +E +++Q+E ++ + + + +
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
+ E+EEK ++E+ +E +K WR + ++ED+ E+EE+ + + +
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMW---GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 198 GENQGE-EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
+ + EK T+ Q K+ QE+K ++EE E+ KK +E +EE+ + K E
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEK--MREEERMREREKKMRE-EEEMMREQEEKMQEQEE 617
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRA-SVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 315
K Q E K+ E + + K E ++ +RL E + + E E +
Sbjct: 618 KMQEQE---EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 674
Query: 316 FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE---EADRKLREEEEKRRLKEE 372
++ Q+Q+E E E+++KK +E+ K ++E+ R++E E ++K+REEEE R +EE
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734
Query: 373 IERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFL 418
+ E EK Q+ E+ ++K ++ ++ E+ E L
Sbjct: 735 ---KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Score = 102 bits (254), Expect = 9e-22
Identities = 102/373 (27%), Positives = 178/373 (47%), Gaps = 23/373 (6%)
Query: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQ-NSVPDEEAKTTTTNTQVEG 84
+ EE+ R+ +R QE+ ++QE+E + +Q E+ Q + ++E K ++
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKE----LREQKELREQEEQMQEQEEKMWEQEEKMRE 366
Query: 85 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEK- 143
+E + + E+ +Q R QE R +E D L RM+ E EK
Sbjct: 367 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM 426
Query: 144 -EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
EEK QE+ ++ E K ++ R+ E+ +E++E E+EEK ++ +
Sbjct: 427 REEKKMQEQEKKTRDQEE---KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 483
Query: 203 EEKGTKVQ---AKREKLQEDKPTFKKEE---IKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
EEK + Q ++EKL E + ++EE ++EKI+ +E + K M R++ E
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK-MWRQEKMREQ 542
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316
+ Q E K++ E R T+E E + K EE R R E + E
Sbjct: 543 EDQMWE-QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 317 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERR 376
E++ ++Q+E E EE K +E+ K+ E+EE+ ++QEE K+ E+EEK +EE
Sbjct: 602 EEMMREQEEKMQEQEE--KMQEQEEKMWEQEEKMQEQEE---KMWEQEEKMWEQEEKMWE 656
Query: 377 RAEAAEKRQKMPE 389
+ E+++K+ E
Sbjct: 657 QQRLPEQKEKLWE 669
Score = 88.2 bits (217), Expect = 2e-17
Identities = 89/392 (22%), Positives = 180/392 (45%), Gaps = 42/392 (10%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
++ D EE+ E R R R++++R+ EEE++ + ++++ +N EE +
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMRE--EEETMREQEEKMQKQEENMWEQEEKEWQQ---- 490
Query: 82 VEGDDEAAFLERLARREER--RQKRLQEALERQKEFDPTITDASLSLPS-----RRMQND 134
+RL ++E+ Q+++QE E+ E + I D R+ +
Sbjct: 491 ----------QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 135 TAENETTEKEEKSESRQERY--EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP 192
E++ E+EEK ++++ + E E T+ +K W E+ ++E++ +E E++ +
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 193 KRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMD 248
+ E E+ K+Q + EK+QE + ++E K +EK+ + +E E + M
Sbjct: 601 E-----EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 249 RKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRR 308
++ E K + E K++ E + + +E E K+ + + R
Sbjct: 656 EQQRLPEQKEKLWEH--EKMQEQEKMQEQ---EEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 309 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE--EQRRKQEEADRKLREEEEK 366
E E EK ++++E E EE +++EE+ + EEE EQ K E + K+ E++
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL 770
Query: 367 RRLKEEI-ERRRAEAAEKRQKMPEDGLSDDKK 397
KE++ E + + EK + E ++K
Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Score = 86.7 bits (213), Expect = 5e-17
Identities = 94/393 (23%), Positives = 186/393 (47%), Gaps = 47/393 (11%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQ----VTDQVEVN-AQNSVPDEEAKTT 76
Q EEE RER ++ R+E +++EE + + + +Q E Q +P+++ K
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 77 TTNTQVEGDDEAAFLERLARREER---------RQKRLQEALERQKEFDPTITDASLSL- 126
E +++ E R +E RQ++++E ++ E + + D +
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 127 -PSRRMQNDTAENE--TTEKEEKSESRQ-----ERYEIEETETVTKSYQKNDWRDAEENK 178
RM+ T E E T ++EEK + E+ EE E + + +K ++ + +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 179 KEDK--EKEEEEEEKPKRGSIGEN---QGEEK---GTKVQAKREKLQEDKPTFKKEEIKD 230
+E+K E+EE+ +E+ ++ E + EEK ++ ++EKL E + ++E++++
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 231 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 290
++ K ++ K E K+ KK + + K + E M + K R + +
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM---------REEEEMMREQ 732
Query: 291 GAPQVEAGKRLEELRRRRGETESEEFEKLKQ--KQQEAALELEEL--KKKREERRKVLEE 346
E ++++E E E + +E+ ++ +QQ + E+L +K +E+ K+ E+
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 347 EEQRRKQEEADRKLREEEEKRRLKEEIERRRAE 379
EE+ R QEE K+R +EEK R +EE R + E
Sbjct: 793 EEKMRDQEE---KMRGQEEKMRGQEEKMRGQEE 822
Score = 84.3 bits (207), Expect = 3e-16
Identities = 89/385 (23%), Positives = 173/385 (44%), Gaps = 56/385 (14%)
Query: 27 DEEEAARERRRRARQERLRQKQEE--ESLGQVTDQV------EVNAQNSVPDEEAKTTTT 78
D+EE + ++ RQE++R+++++ E ++ DQ E + ++E KT
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Query: 79 NTQVEGDDEAAFLERLARREER----RQKRLQEALERQKEFDPTITDASLSLPSRRMQND 134
++ ++ E+ R EE +++++QE E+ +E + + + + + +
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641
Query: 135 TAENETTEKEEKS----------------ESRQERYEIEETETVTKSYQKNDWRDAEENK 178
E + E+EEK E QE+ +++E E +K + + E+ K
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 179 KE-DKEKEEEEE---EKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK 234
K D+EK EEE E+ K+ E E+ K+Q + EK+QE + ++E EK+
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE---EKMW 758
Query: 235 KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 294
+ +E E + ++K+ E + K++ E + + E + Q
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHE---------KMQEQEKIWEQ----------EEKMRDQ 799
Query: 295 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 354
E + EE + RG+ E ++ K QE + +E K +E + +EE+ K +
Sbjct: 800 EEKMRGQEE--KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Query: 355 EADRKLREEEEKRRLKEEIERRRAE 379
+ K+RE+EEK R +EE R + E
Sbjct: 858 GQEEKMREQEEKMRGQEEKMREQEE 882
Score = 84.0 bits (206), Expect = 3e-16
Identities = 88/381 (23%), Positives = 184/381 (48%), Gaps = 36/381 (9%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 87
+EE RE+ ++ R++ + ++EE L + ++ + E+ E + E
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 88 AAFLERLARREERRQK---RLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKE 144
+ L +EE+ Q+ ++ E E+ +E + + L + Q E + ++E
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 145 EKSESRQERYEIEETETVTKSYQKNDWRDAE----ENKKEDKEKEEEEEEKPKRGSIGEN 200
E+ + ER E+ E + + Q+ W E E K +++EK+ ++E E
Sbjct: 397 ERMWEQDERLR-EKEERMRE--QEKMWEQVEKMREEKKMQEQEKKTRDQE--------EK 445
Query: 201 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 260
EE+ +++ + +K++E++ T +++E EK++K +E E + +++ E K +
Sbjct: 446 MQEEE--RIREREKKMREEEETMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 261 GEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLK 320
E K++ E + D +E G Q + R E++R + + +E EK++
Sbjct: 501 WE--QEKMQEQEEKIWEQEEKIR-DQEEMWG--QEKKMWRQEKMREQEDQMWEQE-EKMR 554
Query: 321 QKQQEAALELEELKKK-REERRKVLEEEEQRRKQE---EADRKLREEEEKRRLKEEIERR 376
++Q+ + E ++KK +E+ +K ++EE+ R++E E ++K+REEEE R +EE +
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE---K 611
Query: 377 RAEAAEKRQKMPEDGLSDDKK 397
E EK Q+ E ++K
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEK 632
Score = 79.7 bits (195), Expect = 6e-15
Identities = 81/397 (20%), Positives = 181/397 (45%), Gaps = 35/397 (8%)
Query: 32 ARERRRRARQERLRQKQEEESLGQVTDQVEVNA----QNSVPDEEAKTTTTNTQVEGDDE 87
A E +R R K+ + + ++T + + + +N++ +EE K Q ++
Sbjct: 178 AGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQ----EK 233
Query: 88 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 147
E + K L+ LER K P + +L R + + E E ++++
Sbjct: 234 LPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE 293
Query: 148 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE-----------KEEEEEEKPKRGS 196
+ ++ + E E + ++ WR + ++++KE KE E+E+ +
Sbjct: 294 KMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQ 353
Query: 197 -----IGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK----DEKI-KKDKEPKEEVKSF 246
E + E+ K+ + E+L E + +++E K +E++ ++D+ +E+ +
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 247 MDRKKGFTEV-KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 305
+++K + +V K + + M + K T + + + +E + + E + EE
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473
Query: 306 RRRGET--ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE---ADRKL 360
+++ E E EE E +Q+ E +L E +K +E+ K+ E+EE+ R QEE ++K+
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 361 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 397
+E+ R ++++ + + ++ QKM + +KK
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/244 (21%), Positives = 116/244 (47%), Gaps = 11/244 (4%)
Query: 26 DDEEEAARERRRRARQERLRQKQE---EESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
+ EE+ + + Q+RL +++E E Q ++++ + E+ + T +
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
+ D+ E + RE R+K+++E E +E + + + + + + E + E
Sbjct: 702 KTWDQEKMREEESMRE--REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
+EEK +Q E +E + Q+ + +E K D+E++ +E+ RG + +G
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 203 EEKGTKVQAKREKL--QEDKPTFKKEEI--KDEKIKKDKEPKEEVKSFMDRKKGFTEVKS 258
+E+ K+ + EK+ QE+K ++E++ ++EK+++ + +EE + K E K
Sbjct: 820 QEE--KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKM 877
Query: 259 QNGE 262
+ E
Sbjct: 878 REQE 881
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 102 bits (255), Expect = 7e-22
Identities = 86/367 (23%), Positives = 183/367 (49%), Gaps = 28/367 (7%)
Query: 27 DEEEAARERRRRARQERLRQKQEE----ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
++E RE+ + R++ + +++E E GQV +Q + V ++E + QV
Sbjct: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-----EGQVREQEGQVREQEGQV 124
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
+ + RE+ Q R QE R++E + + R + E E
Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQEGQV 180
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
+E++ + R++ ++ E E ++ E+ +K++++ E+EE+ K+ E Q
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ----EEQM 236
Query: 203 EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 262
E+ +VQ + E++Q+ + +K+E E++++ +E E + M ++K TE + Q GE
Sbjct: 237 GEQEEQVQKQEEQVQKQEEQMRKQE---EQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Query: 263 FMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK 322
+++ E R + +E + + GK+ E++ ++ + ++ + KQ+
Sbjct: 294 -QEEQMREQEEQM-REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
Query: 323 QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE 382
+Q E E+++K+ E+ RK +EEQ RKQEE RK +EE+ R+ +E++ ++ + E
Sbjct: 352 EQMGEQE-EQMQKQEEQVRK---QEEQMRKQEEQMRK--QEEQMRKQEEQMGEQKEQMGE 405
Query: 383 KRQKMPE 389
++++M E
Sbjct: 406 QKEQMRE 412
Score = 79.7 bits (195), Expect = 6e-15
Identities = 78/353 (22%), Positives = 162/353 (45%), Gaps = 36/353 (10%)
Query: 27 DEEEAARERRRRARQERLRQKQEE----ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
++E RE+ + R++ + +++E E GQV +Q + V ++E + QV
Sbjct: 112 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-----EGQVREQEGQVREQEGQV 166
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT----AEN 138
+ + RE+ Q R QE ++E + + +MQ +
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
Query: 139 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 198
E K+E+ QE ++ E V K Q+ R EE +E +E+ E+EE+ +
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQK--QEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284
Query: 199 ENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKS 258
Q E+ G + + RE QE++ ++E+++++ +++ +E+ + +++ E K
Sbjct: 285 TEQEEQTGEQEEQMRE--QEEQMREQEEQMREQ----EEQMREQEEQMGKQEEQMWEQKE 338
Query: 259 QNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEK 318
Q E K E + +E + Q E ++ EE R++ E ++ E+
Sbjct: 339 QMWEQKEQMWKQEE----------QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 319 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 371
+++++++ + E++ +++E+ R E+EEQ +Q+E RK +EE KE
Sbjct: 389 MRKQEEQMGEQKEQMGEQKEQMR---EQEEQMGEQKEQMRK--QEEHMGEQKE 436
Score = 78.2 bits (191), Expect = 2e-14
Identities = 62/330 (18%), Positives = 156/330 (47%), Gaps = 41/330 (12%)
Query: 57 TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFD 116
TD++ + + V ++E + QV + + RE+ Q R QE R++E
Sbjct: 43 TDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 102
Query: 117 PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEE 176
+ + R + E E +E++ + R++ ++ E E + ++ +
Sbjct: 103 VREQEGQV----REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE------QEGQV 152
Query: 177 NKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 236
++E + +E+E + + + G + E +G+ + + Q + ++ Q + + E +++ +++
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
Query: 237 KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVE 296
++ +++ + ++++ + + Q GE +E + Q E
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGE------------------------QEEQVQKQEE 248
Query: 297 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 356
++ EE R++ E E+ E++++++++ + K++ E+ + E+EEQ R+QEE
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ----KEQTEQEEQTGEQEEQMREQEE- 303
Query: 357 DRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
++RE+EE+ R +EE R + E K+++
Sbjct: 304 --QMREQEEQMREQEEQMREQEEQMGKQEE 331
Score = 73.6 bits (179), Expect = 5e-13
Identities = 73/390 (18%), Positives = 177/390 (45%), Gaps = 32/390 (8%)
Query: 38 RARQERLRQKQEE--ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLA 95
R E L++K E E L Q+ + + Q + + + K T + + +
Sbjct: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEGQV------- 54
Query: 96 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 155
RE+ Q R QE R++E + + R + E E +E++ + R++ +
Sbjct: 55 -REQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQEGQVREQEGQVREQEGQ 109
Query: 156 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREK 215
+ E E + ++ + ++E + +E+E + + + G + E +G+ + + Q + ++
Sbjct: 110 VREQEGQVRE------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 163
Query: 216 LQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTF 275
Q + + E + + +++ + +E+ +++ E + Q GE K E
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM- 222
Query: 276 SRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKK 335
G + K+ E + G++ E+++++ + + +E + KQ++Q E E++++
Sbjct: 223 ---GEQEEQMRKQEE-----QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE-EQMRE 273
Query: 336 KREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAEKRQKMPEDGLSD 394
+ E+ K E+ EQ + E + ++RE+EE+ R +E++ + + E+ ++M +
Sbjct: 274 QEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQM 333
Query: 395 DKKPFKCFTPKGSSLKIEERAEFLNKSVQK 424
++ + + K K EE+ + +QK
Sbjct: 334 WEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Score = 64.7 bits (156), Expect = 2e-10
Identities = 52/249 (20%), Positives = 118/249 (47%), Gaps = 15/249 (6%)
Query: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 85
+ E + + + QE QKQEE+ +G+ +Q+ + + ++E + QV+
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQ-MGEQEEQMR-KQEEQMGEQEEQVQKQEEQVQKQ 253
Query: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 145
+E + RE+ Q R QE + K+ + T + +M+ E E +E+
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEE-QMLKQKEQTEQEEQTGEQEEQMR----EQEEQMREQ 308
Query: 146 KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEK 205
+ + R++ ++ E E ++ W E+ ++ ++ ++EE+ ++ E Q +++
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ----EEQMQKQ 364
Query: 206 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM-DRKKGFTEVKSQNGEFM 264
+V+ + E++++ + +K+E E+++K +E E K M ++K+ E + Q GE
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQE---EQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Query: 265 THKLKHTEN 273
K E+
Sbjct: 422 EQMRKQEEH 430
Score = 46.2 bits (108), Expect = 8e-05
Identities = 35/173 (20%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
Q+ Q+ ++EE E+ + R++ + +++EE + + +Q+ + EE
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
E ++ E +E + ++ +E + +Q+E +M+ +
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE---------------QMRK---Q 378
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEE 190
E K+E+ +QE E+ E + + QK R+ EE E KE+ ++EE
Sbjct: 379 EEQMRKQEEQMRKQEEQMGEQKEQMGE--QKEQMREQEEQMGEQKEQMRKQEE 429
Score = 40.0 bits (92), Expect = 0.006
Identities = 35/168 (20%), Positives = 70/168 (41%), Gaps = 34/168 (20%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQ------KQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
Q + +E+ +E + R ++E++R+ KQEE+ Q E Q +E+
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ--- 353
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 135
E +++ E R++E + ++ +E + +Q+E R+ +
Sbjct: 354 -----MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE------------QMRKQEEQM 396
Query: 136 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE 183
E + E+K + R++ ++ E QK R EE+ E KE
Sbjct: 397 GEQKEQMGEQKEQMREQEEQMGE--------QKEQMRKQEEHMGEQKE 436
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 101 bits (252), Expect = 2e-21
Identities = 84/383 (21%), Positives = 180/383 (46%), Gaps = 29/383 (7%)
Query: 21 YQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 80
++ ++EE RE+ + R++ + +++EE + + +++ + EE
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 81 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 140
E +++ E + +E + + L+E + Q++ +R + + +
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ--------EEKRQEEEKIREQE 423
Query: 141 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 200
+E++++ ++ +I E E + +K WR E+ +++K +EEE+ ++ + E
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 201 QGEEKGTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFTEV 256
+ E+ ++ ++EK+ E + +K+E K +EKI++ +E E + M R++ ++
Sbjct: 484 KIHEQ-EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE--EKI 540
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRASVDTK----EAEGAPQVEAGKRLEELRRRRGETE 312
+ Q + + H + R + K E + Q E R EE R + E
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 313 SEEFEKLKQKQQEAALELEEL-----KKKREERRKVLEEEEQRRKQE----EADRKLREE 363
E+ EK+ KQ+E E EE +K RE+ K+ E+EE ++QE E + K+ E+
Sbjct: 601 QEQEEKM-WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
Query: 364 EEKRRLKEEIERRRAEAAEKRQK 386
EEK + +EE R+ E +++K
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEK 682
Score = 97.1 bits (240), Expect = 4e-20
Identities = 87/385 (22%), Positives = 185/385 (48%), Gaps = 42/385 (10%)
Query: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
L + +++ E+E R+ + R++ RQ+QE + Q + + ++E K
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---------EEKIREQEEKI 446
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQK-----RLQEALERQKEFDPTITDASLSLPSRR 130
++ +E + R EE+RQ+ R +E + Q+E R+
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI------------WRQ 494
Query: 131 MQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEE 190
+ + E K+E+ RQE +I E E + ++ WR E+ +++++ EEE+
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEE-KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553
Query: 191 KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 250
+ E + +E+ K+ + EK++E + ++E EKI++ +E ++E + M ++
Sbjct: 554 HEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE---EKIREQEEKRQEQEEKMWKQ 610
Query: 251 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR--- 307
+ + + + K++ E R + + +E G + + ++ E+++ +
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKI-REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 308 --RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 365
R E + E EK ++Q+E E EE+ +++EE K+ E+EE+ +QEE K++E+EE
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE--KMWEQEEKMCEQEE---KMQEQEE 724
Query: 366 K-RRLKEEIERRRAEAAEKRQKMPE 389
K RR +E++ + ++ +KM E
Sbjct: 725 KMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 95.9 bits (237), Expect = 9e-20
Identities = 94/413 (22%), Positives = 188/413 (45%), Gaps = 54/413 (13%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 87
+EE +E + +++ + +++EE + + +++ + EE E +++
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 88 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 147
E + +E + +R +E + ++E + + R Q + + E +E++
Sbjct: 365 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 424
Query: 148 ESRQE------RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEE-------------- 187
QE +I E E + +K WR E+ +++K +EEE
Sbjct: 425 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 188 --EEEKPKRGSIGENQGEEK----GTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDK 237
E+E+ R ++ EEK KV + EK++E + +++E K +EKI++ +
Sbjct: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544
Query: 238 EPKEEVKSFMDRKKGFTEVKSQNGE----FMTHKLKHTENTFSRPGGRASVDTKEAEGAP 293
E E + +++K + E K Q E K++ E R + +E +
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ--EEKIREQEEKRQE 602
Query: 294 QVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER-----RKVLEEEE 348
Q E + EE R + E E+ EK+++ Q+E E EE+ +++EE+ K+ E+EE
Sbjct: 603 QEEKMWKQEEKIREQEEKIQEQEEKIRE-QEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 349 QRRKQEEA-----------DRKLREEEEKRRLKEEIERRRAEAA-EKRQKMPE 389
+ ++QEE ++K+RE+EEK R +EE+ + + E E+ +KM E
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
Score = 90.1 bits (222), Expect = 5e-18
Identities = 89/339 (26%), Positives = 166/339 (48%), Gaps = 35/339 (10%)
Query: 65 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 124
+N++ DEE K Q ++ +E + K L+ LER K L
Sbjct: 211 RNTITDEELKEKNAKLQ----EKLQLVESEKSEIQLNVKELKRKLERAK----------L 256
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND---WRDAEENKKED 181
LP +++Q AE + KE +S S + + ++EE E + Q+ + WR EE +E
Sbjct: 257 LLPQQQLQ---AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ-EEKIQEW 312
Query: 182 KEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEE----IKDEKIKKDK 237
+EK +E+EEK + E + E+ K++ + E + E + +++E K+EK+++ +
Sbjct: 313 EEKIQEQEEKIRE---QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369
Query: 238 EPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVD-TKEAEGAPQVE 296
E E + M R++ K + + K+ E + R + +E E + E
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 297 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK--KKREERRKVLEEEEQRRKQE 354
A +E + R E + E EK +Q+E E E+++ +KR+E+ ++ +EE+ +QE
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 355 EADR---KLREEEEK-RRLKEEIERRRAEAAEKRQKMPE 389
E R K+ E+EEK R+ +E++ R+ + E+ +K+ E
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Score = 81.3 bits (199), Expect = 2e-15
Identities = 99/396 (25%), Positives = 178/396 (44%), Gaps = 46/396 (11%)
Query: 42 ERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE-- 99
+ L++K E L Q++ A + + ++ + QVE E RL +++E
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQQEEK 301
Query: 100 --RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQER-YEI 156
R+++++QE E+ +E + I + + + + E EKEEK ++E +E
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 157 EET-----------ETVTKSYQKNDW------RDAEENKKEDKEKEEEEEEKPKRGSIGE 199
EE E + ++ W R+ EE E ++ E+EE++ + I E
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
Query: 200 NQG-EEKGTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFT 254
+ +E+ K+ + EK++E + +++E K +EKI + ++ +EE K +
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 481
Query: 255 EVK-SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGET-- 311
E K + E K K E V +E + Q E + EE R+ E
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 312 ESEEFEKLKQKQQEAALELEELKKKREERR------KVLEEEEQRRKQEEADRKLREEEE 365
E EE + ++K E EE K++ +E + K+ E+EE+ +QEE K+RE+EE
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE---KIREQEE 598
Query: 366 KRRLKEE----IERRRAEAAEKRQKMPEDGLSDDKK 397
KR+ +EE E + E EK Q+ E ++K
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 99.4 bits (246), Expect = 8e-21
Identities = 107/447 (23%), Positives = 190/447 (42%), Gaps = 58/447 (12%)
Query: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS-VPDEEAKTTTTNTQVEG 84
+ EE+ R+ +R QE+ ++QE+E + +Q ++ Q + ++E K ++
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKE----LREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 85 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKE 144
+E + + E+ +Q R QE R +E D L RM+ E EK
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 145 EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP--KRGSIGENQG 202
++ E +ER + E T Q+ + EEN E +EKE +++ P K + +
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448
Query: 203 EEKGTKVQAKREKL---------------------QEDKPTFKKEEIKDEKIK------- 234
+E+ K+ + EK+ QED+ ++E+++D++ K
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Query: 235 ----------KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASV 284
K++ +E+ K + +K E K+Q E T + R R
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 285 DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL 344
+E E + E + +E + R E + E E+ Q+Q+E E EE ++EE K+
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 345 EEE----EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFK 400
E+E EQ K +E + K+ E+EEK R +EE + E EK Q E ++K
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE---KMREQEEKMQGQEEKMREQEEK--- 682
Query: 401 CFTPKGSSLKIEERAEFLNKSVQKSSG 427
+G K+ E+ E + +K G
Sbjct: 683 ---MQGQEEKMREQEEKMRGQEEKMWG 706
Score = 89.0 bits (219), Expect = 1e-17
Identities = 89/372 (23%), Positives = 178/372 (47%), Gaps = 42/372 (11%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 87
+EE RE+ + R++ + +++E+ L + + E+ Q E+ K Q++ +E
Sbjct: 260 QEERLREQEGKMREQEEKMRRQEKRLRE--QEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 88 AAFLERLARREE-----RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
+ + RE+ R+++RL E ++ +E + + D R + D E
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE----ERMWEQD---ERLRE 370
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
KEE+ +++ +E EE + EE + ++EK+ EEE+ R + Q
Sbjct: 371 KEERMREQEKMWEQEE-------------KMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 203 EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP-KEEVKSFMDRKKGFTEVKSQNG 261
+E+ Q ++E Q+ P K++ + EK+++ +E E+ + D+++ + + K
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM-- 475
Query: 262 EFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQ 321
+ K++ E+ + +E + Q E R+ E R E E E+ K
Sbjct: 476 -WRQEKMREQEDQMWEQ--EEKMRDQEQKMWDQEE---RMWEQDERLREKEERMREQKKM 529
Query: 322 KQQEAALELEELKKKREERRKVLEEEEQRRKQE---EADRKLREEEEKRRLKEE-IERRR 377
QQE ++ E KK +E+ +K ++EE+ R++E E ++K+REEEE R +EE ++ +
Sbjct: 530 WQQEE--KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 378 AEAAEKRQKMPE 389
+ E+ +KM E
Sbjct: 588 EKMREQEEKMWE 599
Score = 86.7 bits (213), Expect = 5e-17
Identities = 85/385 (22%), Positives = 177/385 (45%), Gaps = 45/385 (11%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQ----VTDQVEVN-AQNSVPDEEAKTT 76
Q EEE RER ++ R+E +++EE + + + +Q E Q +P+++ K
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 77 TTNTQVEGDDEAAFLERLARREER---------RQKRLQEALERQKEFDPTITDASLSLP 127
E +++ E R +E RQ++++E ++ E + + D +
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 128 SRRMQNDTAENETTEKEEKSESRQERYEIEET---ETVTKSYQKNDWRDAEENKKEDKEK 184
+ + + EKEE+ +++ ++ EE E T+ +K W E+ ++E++ +
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 185 EEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 244
E E++ + + E E+ K+Q + EK++E + ++E EK+++ +E E +
Sbjct: 564 EREKKMREE-----EEMMREQEEKMQEQEEKMREQEEKMWEQE---EKMQEQEEKMWEQE 615
Query: 245 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL 304
M ++ E K Q E M + + +E E + K E+
Sbjct: 616 EKMWEQE--EEDKMQEQEEMMWEQEEK--------------MQEQEEKMWEQEEKMREQE 659
Query: 305 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEE 364
+ R + E + ++ K ++QE ++ +E +K RE+ K+ +EE+ QEE K+ +E
Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQE-EKMREQEEKMRGQEEKMWGQEE---KMWGQE 715
Query: 365 EKRRLKEEIERRRAEAAEKRQKMPE 389
EK +EE+ + ++++KM E
Sbjct: 716 EKMWGQEEMREKEERIRDQKEKMQE 740
Score = 60.5 bits (145), Expect = 4e-09
Identities = 43/199 (21%), Positives = 97/199 (48%), Gaps = 9/199 (4%)
Query: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 85
D EE+ E R R R++++R+ EEE + + ++++ + + ++E K +++
Sbjct: 551 DQEEKMREEERMREREKKMRE--EEEMMREQEEKMQ-EQEEKMREQEEKMWEQEEKMQEQ 607
Query: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 145
+E + + E+ + ++QE E E + + + + + + E + E+EE
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Query: 146 KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEK---PKRGSIGENQG 202
K + ++E+ +E + Q+ R+ EE + +EK +EEK + G+ +
Sbjct: 668 KMQGQEEKMREQEEK---MQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724
Query: 203 EEKGTKVQAKREKLQEDKP 221
EK +++ ++EK+QE P
Sbjct: 725 REKEERIRDQKEKMQERLP 743
Score = 56.6 bits (135), Expect = 6e-08
Identities = 82/351 (23%), Positives = 153/351 (43%), Gaps = 57/351 (16%)
Query: 98 EERRQKRLQEALERQKEFDPT----ITDASLSLPSRRMQNDTAENETTEK------EEKS 147
E+ RQ +L EA ++ ++ + + +++ N T TT + +EK
Sbjct: 15 EKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKK 74
Query: 148 ESRQE----RYEIEETETVTK--SYQKNDWRDAEENKKEDKEKEEEE---EEKPKRGSI- 197
S Q R EIE + + + QK + A ++ K E+ E K G +
Sbjct: 75 ASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLH 134
Query: 198 ------GENQGEEKGTKVQAKR-----EKLQEDKPTFKKE----EIKDEKIKKDKEPKEE 242
GE Q K+ E+L +++ E I +E++KK +E
Sbjct: 135 HSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQE 194
Query: 243 VKSFMDRKKGFTEV-------KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQV 295
+ +K ++ K + +F+ +++ NT R + +E E +
Sbjct: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQ--TNTLQEEMWRQEEELREQEKKIRK 252
Query: 296 EAGK---RLEELRRRRGETESEEFEKLKQKQQ---EAALELEELKKKREERRKVLEEEEQ 349
+ K + E LR + G+ +E EK++++++ E EL E +K+ E++K+ E+EEQ
Sbjct: 253 QEEKMWRQEERLREQEGKMREQE-EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 350 RRKQEEADRKLREEEEKRRLKEEIERRRAE---AAEKRQKMPEDGLSDDKK 397
++QEE K+ E+EEK R +EE R+ E EK+ + E + D ++
Sbjct: 312 MQEQEE---KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/147 (27%), Positives = 70/147 (47%), Gaps = 35/147 (23%)
Query: 302 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL----------------- 344
EEL+++ E + E+ + ++ E L ++ELK+K E + +L
Sbjct: 183 EELKKKNAELQ-EKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 345 ---EEEEQRRKQEE----ADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 397
E+E++ RKQEE + +LRE+E K R +EE RR+ EKR + E L + +K
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ----EKRLREQEKELREQEK 297
Query: 398 PFKCFTPKGSSLKIEERAEFLNKSVQK 424
+ K+ E+ E + + +K
Sbjct: 298 ELR------EQKKLREQEEQMQEQEEK 318
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 96.7 bits (239), Expect = 5e-20
Identities = 104/485 (21%), Positives = 195/485 (40%), Gaps = 37/485 (7%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
+R D + E RE+ R +++R R++Q + + E Q + + N Q
Sbjct: 72 ERETDRKRERRREKDRHRKRDRHRERQRDR-------EKERERQTDRERDRQREKERNRQ 124
Query: 82 VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
E + E ER R RQ Q ERQ++ + R Q D T
Sbjct: 125 KERERET---EREGERGRDRQTDGQRERERQRDAEK----------ERERQTDRERQRQT 171
Query: 142 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 201
E+ + E +E+ E E + ++N D + ++E+E E E + +R + +
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 202 GEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG 261
++ K + +REK E +E + + ++DKE + E DR + E + Q
Sbjct: 232 -RDRQRKTEREREKQAE------RERASERETERDKERERERDRDRDRDRRQKERERQTD 284
Query: 262 EFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQ 321
+ + T R R +E E + E + E R R+ ETE + EK ++
Sbjct: 285 RKRQRRTERDRET-ERKRERQRERERERERNRKRERERERERERERQRETERDR-EKERE 342
Query: 322 KQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA 381
++++ E++ + ++ R + E +R ++ E DR+ E E+R + + +R R +
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER--ERDRDRDRQKER 400
Query: 382 EKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKID 441
E++ + DG + +K + + S ER + +K G + + +
Sbjct: 401 ERQTEKDRDGQRETEKQREREKDRES-----ERGRERGREREKQKGRERDRERQTDRQAG 455
Query: 442 SRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETA 501
+ ++ T + + SD P G+R KS E S+ G P K +
Sbjct: 456 RQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIR-WKSSPEDPKAASTRFPWGRPAKASR 514
Query: 502 GLKVG 506
G G
Sbjct: 515 GRVAG 519
Score = 85.9 bits (211), Expect = 9e-17
Identities = 84/361 (23%), Positives = 157/361 (43%), Gaps = 31/361 (8%)
Query: 35 RRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERL 94
RRR QE R++ LGQ + + + +E + Q E + + +R
Sbjct: 28 RRRPGSQESPRRR----GLGQAHKDADGDDRERNRQKERERRREKRQTERETDR---KRE 80
Query: 95 ARREERRQKRLQEALERQKEFDP-----TITDASLSLPSRRMQNDTAENETTEKEEKSES 149
RRE+ R ++ ERQ++ + T + R + E ET + E+
Sbjct: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 150 RQE--RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGT 207
RQ + E E K ++ R+ + + +++KE E E +N+ E +
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE---------KNRQERRER 191
Query: 208 KVQAKREKLQEDKPTFK-KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTH 266
+ Q ++E ED+ + + +E ++ + + + E K + DR++ + + E
Sbjct: 192 ERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251
Query: 267 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 326
+ TE R R D Q E ++ + R+RR E + E E+ +++Q+E
Sbjct: 252 SERETERDKERERER---DRDRDRDRRQKERERQTDRKRQRRTERD-RETERKRERQRER 307
Query: 327 ALELEELKKKREERRKVLEEEEQRRKQEEADR-KLREEEEKRRLKEEIERRRAEAAEKRQ 385
E E +K+ ER + E E +R+++ E DR K RE + KR+ + + ER R E R+
Sbjct: 308 ERERERNRKRERERER--ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR 365
Query: 386 K 386
+
Sbjct: 366 Q 366
Score = 82.8 bits (203), Expect = 8e-16
Identities = 74/369 (20%), Positives = 150/369 (40%), Gaps = 55/369 (14%)
Query: 9 GRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSV 68
G+R +R + E R+ R ++ER R+K +E + + + N
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 69 PDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPS 128
E + + E + E +R RE RQ++ + E+Q E +
Sbjct: 205 HSERGRERERERETETETER---KRQTDRERDRQRKTEREREKQAERE------------ 249
Query: 129 RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE 188
R + +T ++ E+E + ++R + E + Q+ RD E +K ++++E E
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 189 EEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMD 248
E + R KRE+ +E + +++ + +K++E K + ++ MD
Sbjct: 310 ERERNR-----------------KRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 249 RKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRR 308
R++ Q G R G R + +E E ++ + EE R R
Sbjct: 353 RER-----NRQTG---------------REGRRQAERERERERERDRQSAREREERERDR 392
Query: 309 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 368
+E E+ +K ++ E E+ +++ ++R E + R +E +K RE + +R+
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRE---SERGRERGREREKQKGRERDRERQ 449
Query: 369 LKEEIERRR 377
+ R+R
Sbjct: 450 TDRQAGRQR 458
Score = 77.0 bits (188), Expect = 4e-14
Identities = 71/320 (22%), Positives = 139/320 (43%), Gaps = 40/320 (12%)
Query: 83 EGDDEAAFLERLARREERRQKRLQEA-LERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
+GDD R RE RR+KR E +R++E RR + D
Sbjct: 50 DGDDRER--NRQKERERRREKRQTERETDRKRE--------------RRREKDRHRKRDR 93
Query: 142 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 201
+E + + +ER + E ++ R+ E N+++++E+E E E + R + Q
Sbjct: 94 HRERQRDREKERERQTDRE-------RDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 202 GE-------EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE---PKEEVKSFMDR-- 249
E EK + Q RE+ ++ + +KE +++ ++ +E +E+ DR
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 250 KKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG 309
++G + + E T + + T+ R R +E E + E E R +
Sbjct: 207 ERGRERERERETETETERKRQTD----RERDRQRKTEREREKQAERERASERETERDKER 262
Query: 310 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 369
E E + ++Q+E + + +++R ER + E + +R+++ E +R+ + E+ R
Sbjct: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Query: 370 KEEIERRRAEAAEKRQKMPE 389
+E R+ E R+K E
Sbjct: 323 RERERERQRETERDREKERE 342
Score = 65.1 bits (157), Expect = 2e-10
Identities = 61/277 (22%), Positives = 123/277 (44%), Gaps = 15/277 (5%)
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
+P+ Q T E T + S R E + ++++ D D E N++ KE+E
Sbjct: 6 VPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQ--KERE 63
Query: 186 EEEE----------EKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 235
E ++ +R ++ ++ + Q REK +E + +++ ++++ +
Sbjct: 64 RRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR 123
Query: 236 DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQV 295
KE + E + +R + + E K E R R + ++ E +
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK 183
Query: 296 EAGKRLEELRRRRGE--TESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 353
+R E R+R E TE E+ +++++E E E +K++ +R + + + +R ++
Sbjct: 184 NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
Query: 354 EEADRKLREEEEKRRLKE-EIERRRAEAAEKRQKMPE 389
++A+R+ E E R KE E ER R ++RQK E
Sbjct: 244 KQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Query: 286 TKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLE 345
T + G VE L+ RRR G ES L Q ++A + E +++E R+
Sbjct: 9 TADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR--- 65
Query: 346 EEEQRRKQEEADRKL-REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 397
E+R+ + E DRK R E+ R K + R R EK ++ D D ++
Sbjct: 66 -REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 94.0 bits (232), Expect = 3e-19
Identities = 86/356 (24%), Positives = 177/356 (49%), Gaps = 27/356 (7%)
Query: 42 ERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERR 101
+ L++K E L Q++ A + + ++ + QVE E RL +++E +
Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQQEEK 289
Query: 102 QKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE-RYEIEE-- 158
R +E ++ ++E I + + + + E EKEEK ++E +E EE
Sbjct: 290 MWRQEEKIQEREE---KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 159 TETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQE 218
E K +++ R+ EE ++E+++ E+E+ + + + + K++ + EK++E
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-----EKIREQEEKIRE 401
Query: 219 DKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENT 274
+ +++E K +EK+ + +E +E + M R++ +++ Q + + K E
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE--EKIREQEKKIREQEEKIREQE 459
Query: 275 FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 334
+ +E + Q EA + +E + RR E + E EK ++Q+E E EE+
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQ-EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 335 KKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAEKRQKMPE 389
+++EE K+ E+EE+ +QEE K++E+EEK RR +E++ + ++ +KM E
Sbjct: 519 QEQEE--KMWEQEEKMCEQEE---KMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 88.2 bits (217), Expect = 2e-17
Identities = 95/375 (25%), Positives = 176/375 (46%), Gaps = 64/375 (17%)
Query: 65 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 124
+N++ DEE K Q ++ +E + K L+ LER K L
Sbjct: 199 RNTITDEELKEKNAKLQ----EKLQLVESEKSEIQLNVKELKRKLERAK----------L 244
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND---WRDAEENKKED 181
LP +++Q AE + KE +S S + + ++EE E + Q+ + WR EE +E
Sbjct: 245 LLPQQQLQ---AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ-EEKIQER 300
Query: 182 KEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEI----KDEKIKKDK 237
+EK +E+EEK + E+ K++ + E + E + +++E K+EKI++ +
Sbjct: 301 EEKIQEQEEKIR----------EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 350
Query: 238 EPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEA 297
E E + ++ E K Q E + + K E A + +E + Q E
Sbjct: 351 EKMHEQEKIREQ-----EEKRQEEEKIREQEKRQEQ-------EAKMWRQEEKIREQEEK 398
Query: 298 GKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKK----REERRKVLEEEEQRRKQ 353
+ EE+ + + E E+ EK+ ++++E + E+++++ RE+ +K+ E+EE+ R+Q
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 354 EEADRKLREEEEKRRLKE----EIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSL 409
EE ++E+EEK +E E E + E EK ++ E +KK +
Sbjct: 459 EE---MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK------IREQEE 509
Query: 410 KIEERAEFLNKSVQK 424
KI E+ E + + +K
Sbjct: 510 KIREQEEMMQEQEEK 524
Score = 78.6 bits (192), Expect = 1e-14
Identities = 86/354 (24%), Positives = 158/354 (44%), Gaps = 69/354 (19%)
Query: 21 YQRNDDDEEEA--ARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTT 78
+ R + +EE +E + + R+E++ Q+QEE+ Q EE
Sbjct: 279 WNRLNQQQEEKMWRQEEKIQEREEKI-QEQEEKIREQ---------------EEKMRRQE 322
Query: 79 NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN 138
E +++ E + +E + + L+E + Q++ R Q + +
Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI--------------REQEEKRQE 368
Query: 139 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 198
E +E++ QE + E + + Q+ R+ EE +E +EK E+EEK
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIRE--QEEKIREQEEMMQEQEEKMGEQEEKMWE---Q 423
Query: 199 ENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKS 258
E + +E+ K++ + EK++E + +++E EKI++ +E +E + K G
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQE---EKIREQEEMMQE----QEEKMG-----E 471
Query: 259 QNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEK 318
Q G+ + K E + E + E R +E + R E + E E+
Sbjct: 472 QEGKMCEQEAKMQE---------------QEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 319 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEE 372
+ Q+Q+E E EE K E+ K+ E+EE+ R+QEE K+RE+E + R +EE
Sbjct: 517 MMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEE---KMREQEVRLRQQEE 565
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/217 (23%), Positives = 100/217 (46%), Gaps = 21/217 (9%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
+I Q EEE RE+ +R QE +QEE+ + + +++ + EE
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 78 TNTQVEGDDEAAFLERLARREERR----QKRLQEALERQKEFDPTITDASLSLPSRRMQN 133
E ++E E RR+E + +K+++E E+ +E + + + + + +
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 134 DTAENETTEKEEKSESRQERY------------EIEETETVTKSYQKNDWRDAEENKKED 181
E + E+EEK ++E+ +I E E + + ++ W + EE E
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW-EQEEKMCEQ 535
Query: 182 KEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQE 218
+EK +E+EEK +R E + E+ +++ + EK+QE
Sbjct: 536 EEKMQEQEEKMRRQ---EEKMREQEVRLRQQEEKMQE 569
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/224 (21%), Positives = 106/224 (47%), Gaps = 16/224 (7%)
Query: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQE------EESLGQVTDQVEVNAQNSVP 69
L + +++ E+E R+ + R++ RQ+QE EE + + +++ +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE 408
Query: 70 DEEAKTTTTNTQVEGDDEAAFLERLARREERR----QKRLQEALERQKEFDPTITDASLS 125
EE E ++E E RR+E + +K+++E E+ +E + + +
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
+ + + E E +E++ + R++ +I E E + Q+ R+ EE +E +EK
Sbjct: 469 MGEQ--EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE-QEEKIREQEEMMQEQEEKM 525
Query: 186 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK 229
E+EEK E + +E+ K++ + EK++E + +++E K
Sbjct: 526 WEQEEKMCE---QEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 93.2 bits (230), Expect = 6e-19
Identities = 78/372 (20%), Positives = 178/372 (47%), Gaps = 27/372 (7%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 87
+EE +E + +++ + +++EE + + +++ + EE E +++
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 88 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 147
LE + +E + + L+E + Q++ +R + + + +E+++
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQ--------EEKRQEEEKIREQEKRQEQEA 416
Query: 148 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGT 207
+ ++ +I E E + +K WR E+ +++K +EEE+ ++ + E + E+
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ-E 475
Query: 208 KVQAKREKLQEDKPTFKKEEI---KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM 264
++ ++EK+ E + K+EE ++EK+ +E E + M R++ + +
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 265 THKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK-- 322
K++ E + ++ E + E +R EE R + E E+ EK++++
Sbjct: 536 EEKIREQEEMMQEQEEKMG---EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 323 ----QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRR 377
Q+E E EE+ +++EE K+ E+EE+ +QEE K++E+EEK RR +E++ +
Sbjct: 593 KIWEQEEKIREQEEMMQEQEE--KMWEQEEKMCEQEE---KMQEQEEKMRRQEEKMWEQE 647
Query: 378 AEAAEKRQKMPE 389
++ +KM E
Sbjct: 648 VRLRQQEEKMQE 659
Score = 90.5 bits (223), Expect = 4e-18
Identities = 89/372 (23%), Positives = 179/372 (48%), Gaps = 29/372 (7%)
Query: 42 ERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE-- 99
+ L++K E L Q++ A + + ++ + QVE E RL +++E
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQQEEK 301
Query: 100 --RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE 157
R+++++QE E+ +E + I + + + + E EKEEK ++E +
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM--MW 359
Query: 158 ETETVTKSYQKNDW------RDAEENKKEDKEKEEEEEEKPKRGSIGENQG-EEKGTKVQ 210
E E + ++ W R+ EE E ++ E+EE++ + I E + +E+ K+
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419
Query: 211 AKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTH 266
+ EK++E + +++E K +EKI + ++ +EE K + E K + E +
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 267 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 326
+ + V +E + Q E + EE R+ E E+ EK+++ Q+E
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE-QEEK 538
Query: 327 ALELEELKKKREER-----RKVLEEEEQRRKQE---EADRKLREEEEKRRLKEEIERRRA 378
E EE+ +++EE+ K+ E+E+ RR++E E + K+RE++EK R +EE +
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 379 EAAEKRQKMPED 390
E ++++M ++
Sbjct: 599 EKIREQEEMMQE 610
Score = 85.9 bits (211), Expect = 9e-17
Identities = 85/334 (25%), Positives = 161/334 (48%), Gaps = 40/334 (11%)
Query: 65 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 124
+N++ DEE K Q ++ +E + K L+ LER K L
Sbjct: 211 RNTITDEELKEKNAKLQ----EKLQLVESEKSEIQLNVKELKRKLERAK----------L 256
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND---WRDAEENKKED 181
LP +++Q AE + KE +S S + + ++EE E + Q+ + WR EE +E
Sbjct: 257 LLPQQQLQ---AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ-EEKIQEW 312
Query: 182 KEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 241
+EK +E+EEK + E+ K++ + EK++ + + K+EK+++ +E
Sbjct: 313 EEKIQEQEEKIR----------EQEEKIREQEEKMRRQEEMMWE---KEEKMRRQEEMMW 359
Query: 242 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDT-KEAEGAPQVEAGKR 300
E + M R + K + + K+ E + R + +E E + EA
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419
Query: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKK--KREERRKVLEEEEQRRKQEEADR 358
+E + R E + E EK +Q+E E E++++ KR+E+ ++ +EE+ R+QEE R
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 359 ---KLREEEEKRRLKEEIERRRAEAAEKRQKMPE 389
K+ E+E+ R+ +E++ R+ + ++ +K+ E
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Score = 85.9 bits (211), Expect = 9e-17
Identities = 92/377 (24%), Positives = 176/377 (46%), Gaps = 51/377 (13%)
Query: 21 YQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 80
++ ++EE RE+ + R++ + +++EE + + +++ + EE
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 81 QVEGDDEAAFLE-------RLARREERRQ----------KRLQEALERQKEFDPTITDAS 123
E +++ LE ++ +EE+RQ ++ QEA ++E +
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
Query: 124 LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE 183
+ ++M + EK + E RQE+ E+ E + Q+ WR E K ++E
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE-QEEIWRQKE--KMHEQE 488
Query: 184 KEEEEEEKPKRGSIGENQGEEKGTKVQAKREKL--QEDKPTFKKEEIKD--EKIKKDKEP 239
K ++EEK R E + ++ K++ + EK+ QE+K ++E+I++ EKI++ +E
Sbjct: 489 KIRKQEEKVWRQ---EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 240 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGK 299
+E + K G E K Q E K++ E + +E + Q E +
Sbjct: 546 MQE----QEEKMGEQEEKMQEQE----KMRRQEE---------KIREQEEKIREQKEKIR 588
Query: 300 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE----E 355
EE + E + E E++ Q+Q+E E EE K E+ K+ E+EE+ R+QE E
Sbjct: 589 EQEE-KIWEQEEKIREQEEMMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEEKMWE 645
Query: 356 ADRKLREEEEKRRLKEE 372
+ +LR++EEK + +E
Sbjct: 646 QEVRLRQQEEKMQEHQE 662
Score = 85.1 bits (209), Expect = 2e-16
Identities = 83/352 (23%), Positives = 164/352 (46%), Gaps = 25/352 (7%)
Query: 43 RLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQ 102
RL Q+QEE+ Q ++ + + ++E K ++ +E RR+E
Sbjct: 293 RLNQQQEEKMWRQ--EEKIQEWEEKIQEQEEKIREQEEKIREQEEKM------RRQEEMM 344
Query: 103 KRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 162
+E + RQ+E + L + + E EK + E +E+ E + E
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 163 TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPT 222
+ +K ++A+ ++E+K +E+EE+ + + + + + + + EK QE +
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 464
Query: 223 FKKEEI--KDEKIKKDKEPKEEVKSF--MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRP 278
+++EE + E+I + KE E + + K E K + E K++ E R
Sbjct: 465 WRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE---EKIREQEEKMWRQ 521
Query: 279 GGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 338
+ +E + Q E + EE+ + + E E+ EK++++++ E +K RE
Sbjct: 522 --EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE----EKIRE 575
Query: 339 ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA-EKRQKMPE 389
+ K+ E++E+ R+QEE K+ E+EEK R +EE+ + + E E+ +KM E
Sbjct: 576 QEEKIREQKEKIREQEE---KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Score = 78.6 bits (192), Expect = 1e-14
Identities = 103/429 (24%), Positives = 194/429 (45%), Gaps = 41/429 (9%)
Query: 15 ALSQIAYQRNDDDE--EEAARER--------RRRARQERLRQKQE--EESLGQVTDQVEV 62
ALS +A Q+ D EE +ER R E L++K +E L Q+ + +
Sbjct: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL-QLVESEKS 238
Query: 63 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA 122
Q +V + + K + A + L + + +LQ +E + ++
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 123 SLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDK 182
+ + + E + E+EEK ++E+ I E E + ++ W + EE + +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEK--IREQEEKMRRQEEMMW-EKEEKMRRQE 355
Query: 183 EKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK-KDKEPKE 241
E E+EEK +R E EK K++ EK+ E + ++EE + E+ K +++E ++
Sbjct: 356 EMMWEKEEKMRRL---EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
Query: 242 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 301
E ++ M R++ +++ Q K++ E R + E E + E +
Sbjct: 413 EQEAKMWRQE--EKIREQE-----EKIREQEKKMWRQEEKIH----EQEKIREEEKRQEQ 461
Query: 302 EELRRRRGET-ESEEFEKLKQKQQEAA-LELEELKKKREERRKVLEEEEQRRKQEE---A 356
EE+ R+ + E EE + K+K E + +E K R+E + +EE+ R ++E+
Sbjct: 462 EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521
Query: 357 DRKLREEEEKRRLKEEIERRRAE-AAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERA 415
+ K+RE+EEK R +EE R + E E+ +KM E ++K + + KI E+
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE----QEEKMQEQEKMRRQEEKIREQE 577
Query: 416 EFLNKSVQK 424
E + + +K
Sbjct: 578 EKIREQKEK 586
Score = 53.5 bits (127), Expect = 5e-07
Identities = 52/230 (22%), Positives = 111/230 (48%), Gaps = 21/230 (9%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 87
E+E RE +R QE + +++E+ + +Q E+ Q E+ K +V +E
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEK-----IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502
Query: 88 AAF--LERLARREE---RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
E++ +EE R++++++E E+ +E + I + + + + E E
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM--QEQEEKMGEQEEKM 560
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
+E++ RQE E+ E + + QK R+ EE E +EK E+E+ + E +
Sbjct: 561 QEQEKMRRQEEKIREQEEKIRE--QKEKIREQEEKIWEQEEKI-REQEEMMQEQ--EEKM 615
Query: 203 EEKGTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMD 248
E+ K+ + EK+QE + +++E K + ++++ +E +E + ++
Sbjct: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 92.8 bits (229), Expect = 7e-19
Identities = 85/374 (22%), Positives = 179/374 (47%), Gaps = 36/374 (9%)
Query: 21 YQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 80
++ ++EE RE+ + R++ + +++EE + + +++ + EE
Sbjct: 373 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 432
Query: 81 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 140
E + E++ EE+ + QE + Q+E R+ + E E
Sbjct: 433 MWEKE------EKIRELEEKMHE--QEKIREQEE-------------KRQEEEKIREQEK 471
Query: 141 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 200
+++E RQE +I E E + ++ WR E+ +++K +EEE+ ++ + E
Sbjct: 472 RQEQEAKMWRQEE-KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 201 QGEEKGTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFTEV 256
+ E+ ++ ++EK+ E + +K+E K +EK+ +E E + + R++ ++
Sbjct: 531 KIREQ-EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE--EKI 587
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316
+ Q + + K E + +E + Q E + EE RR+ E E+
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Query: 317 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIER 375
+K+++ Q+E E EE+ +++EE K+ E+EE+ +QEE K++E+EEK RR +E++
Sbjct: 648 KKIRE-QEEKIREQEEMMQEQEE--KMWEQEEKMCEQEE---KMQEQEEKMRRQEEKMWE 701
Query: 376 RRAEAAEKRQKMPE 389
+ ++ +KM E
Sbjct: 702 QEVRLRQQEEKMQE 715
Score = 86.3 bits (212), Expect = 7e-17
Identities = 97/384 (25%), Positives = 180/384 (46%), Gaps = 45/384 (11%)
Query: 42 ERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE-- 99
+ L++K E L Q++ A + + ++ + QVE E RL +++E
Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQQEEK 362
Query: 100 --RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE 157
R+++++QE E+ +E + I + + + + E EKEEK RQE E
Sbjct: 363 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR-RQEEMMWE 421
Query: 158 ETETVTKSYQ-----KNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG-EEKGTKVQA 211
+ E + + + + R+ EE E ++ E+EE++ + I E + +E+ K+
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 212 KREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM--- 264
+ EK++E + +++E K +EKI + ++ +EE K + E K + E +
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 265 -------THKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 317
K++ E R + +E + Q E R EE R + E E+ E
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQ--EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 318 KLK------QKQQEAALELEEL-----KKKREERRKVLEEEEQRRKQEEADRKLREEEEK 366
K++ Q+Q+E E EE +K +E+ K+ +EE+ R+QE +K+RE+EEK
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE---KKIREQEEK 656
Query: 367 RRLKEEIERRRAEAA-EKRQKMPE 389
R +EE+ + + E E+ +KM E
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCE 680
Score = 85.1 bits (209), Expect = 2e-16
Identities = 97/369 (26%), Positives = 175/369 (47%), Gaps = 38/369 (10%)
Query: 43 RLRQKQEE------ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAF-LERLA 95
RL Q+QEE E + + ++++ + + ++E K ++ +E + E
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 96 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 155
RR+E +E + RQ+E + + + R ++ E E ++E E RQE +
Sbjct: 413 RRQEEMMWEKEEKMRRQEEM---MWEKEEKI--RELEEKMHEQEKIREQE--EKRQEEEK 465
Query: 156 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS--IGENQGEEKGTKVQAKR 213
I E E + K WR EE +E +EK E+EEK R I E + + K Q +
Sbjct: 466 IREQEKRQEQEAKM-WRQ-EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 214 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTEN 273
E ++++ ++EEI +K +K E +E+++ + K E K + E K++ E
Sbjct: 524 EMWRQEEKIREQEEIWRQK-EKIHEQEEKIRK-QEEKMWRQEEKMHDQE---EKIREQEE 578
Query: 274 TFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL-----KQKQQEAAL 328
R + +E + Q E + EE+ + + E E+ EK+ K ++QE +
Sbjct: 579 KVWRQ--EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Query: 329 ELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 388
+E +K RE+ +K+ E+EE+ R+QEE ++E+EEK +EE + E EK Q+
Sbjct: 637 RRQE-EKIREQEKKIREQEEKIREQEE---MMQEQEEKMWEQEE---KMCEQEEKMQEQE 689
Query: 389 EDGLSDDKK 397
E ++K
Sbjct: 690 EKMRRQEEK 698
Score = 84.7 bits (208), Expect = 2e-16
Identities = 86/335 (25%), Positives = 163/335 (48%), Gaps = 41/335 (12%)
Query: 65 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 124
+N++ DEE K Q ++ +E + K L+ LER K L
Sbjct: 272 RNTITDEELKEKNAKLQ----EKLQLVESEKSEIQLNVKELKRKLERAK----------L 317
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND---WRDAEENKKED 181
LP +++Q AE + KE +S S + + ++EE E + Q+ + WR EE +E
Sbjct: 318 LLPQQQLQ---AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ-EEKIQEW 373
Query: 182 KEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 241
+EK +E+EEK + E+ K++ + EK++ + + K+EK+++ +E
Sbjct: 374 EEKIQEQEEKIR----------EQEEKIREQEEKMRRQEEMMWE---KEEKMRRQEEMMW 420
Query: 242 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDT-KEAEGAPQVEAGKR 300
E + M R++ K + + K+ E + R + +E E + EA
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480
Query: 301 LEELRRRRGETESEEFEKLKQKQQEAALELEELKK--KREERRKVLEEEEQRRKQEEADR 358
+E + R E + E E+ +Q+E E E++++ KR+E+ ++ +EE+ R+QEE R
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 359 ---KLREEEEK-RRLKEEIERRRAEAAEKRQKMPE 389
K+ E+EEK R+ +E++ R+ + ++ +K+ E
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE 575
Score = 80.1 bits (196), Expect = 5e-15
Identities = 81/346 (23%), Positives = 155/346 (44%), Gaps = 55/346 (15%)
Query: 33 RERRRRARQERLRQKQEE--ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAF 90
+E + R ++E + +K+E+ E ++ +Q ++ Q EE K + E + +
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 91 LERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESR 150
E R +E + + +E + RQ+E + +R + + + + E+ E
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEE--KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 151 QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQ 210
+++ +I E E + ++ WR +E K D+E++ E+E+ KV
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWR--QEEKMHDQEEKIREQEE----------------KVW 581
Query: 211 AKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH 270
+ EK++E + +++E EKI++ +E +E + K G E K E K++
Sbjct: 582 RQEEKIREQEEKIREQE---EKIREQEEMTQE----QEEKMGEQEEKMCEQE---EKMQE 631
Query: 271 TENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALEL 330
E R E R +E + R E + E E++ Q+Q+E E
Sbjct: 632 QEEKMRRQ-----------------EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 331 EELKKKREERRKVLEEEEQRRKQE----EADRKLREEEEKRRLKEE 372
EE K E+ K+ E+EE+ R+QE E + +LR++EEK + +E
Sbjct: 675 EE--KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 71.6 bits (174), Expect = 2e-12
Identities = 82/350 (23%), Positives = 152/350 (43%), Gaps = 74/350 (21%)
Query: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
L + +++ E+E R+ + R++ RQ+QE + Q + + ++E K
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---------EEKIREQEEKI 493
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 135
++ +E + R EE+RQ+ QE + RQ+E
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQE--QEEMWRQEE--------------------- 530
Query: 136 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 195
+ E+ E +++ +I E E + ++ WR EE + +EK E+EE
Sbjct: 531 ------KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ-EEKMHDQEEKIREQEE----- 578
Query: 196 SIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 255
KV + EK++E + +++E EKI++ +E +E + K G E
Sbjct: 579 ------------KVWRQEEKIREQEEKIREQE---EKIREQEEMTQE----QEEKMGEQE 619
Query: 256 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 315
K E K++ E R + +E + Q E + EE+ + + E E+
Sbjct: 620 EKMCEQE---EKMQEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 316 FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 365
EK+ + Q+E E EE +++EE K+ E+E + R+QEE K++E +E
Sbjct: 675 EEKMCE-QEEKMQEQEEKMRRQEE--KMWEQEVRLRQQEE---KMQEHQE 718
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/224 (22%), Positives = 112/224 (50%), Gaps = 21/224 (9%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS-VPDEEAKTTTTNTQVEGDD 86
E+E RE +R QE + +++E+ + +Q E+ Q + ++E K ++ +
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEK-----IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Query: 87 EAAF--LERLARREE---RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
E E++ +EE R++++++E E+ +E + I + + + E +
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 142 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEK----PKRGSI 197
E+EEK + ++E+ +E + Q+ R+ EE +E +E +E+EEK ++
Sbjct: 624 EQEEKMQEQEEKMRRQEEKI---REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 241
E + +E+ K++ + EK+ E + +++E EK+++ +E E
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQE---EKMQEHQEHLE 721
Score = 54.3 bits (129), Expect = 3e-07
Identities = 47/214 (21%), Positives = 98/214 (45%), Gaps = 15/214 (7%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQ---EEESLGQVTDQVEVNAQNSVPDEEAKTTTT 78
++ + EE +E + R ++E RQK+ E+E + ++ + + D+E K
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576
Query: 79 NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN 138
+V +E + RE+ + R QE + +++E + + +MQ +
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Query: 139 ETTE---KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 195
E +E++ + R++ +I E E + + ++ W + EE E +EK +E+EEK +R
Sbjct: 637 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW-EQEEKMCEQEEKMQEQEEKMRR- 694
Query: 196 SIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK 229
+E+ Q R + QE+K +E ++
Sbjct: 695 -------QEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 52.0 bits (123), Expect = 1e-06
Identities = 61/281 (21%), Positives = 126/281 (44%), Gaps = 37/281 (13%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEE---ESLGQVTDQVE--------VNAQN 66
+I Q EEE RE+ +R QE +QEE E ++ +Q E ++ Q
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Query: 67 SVPDEEAKTTTTNT-----QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITD 121
+ +EE + ++ +E + +E + ++ +E + RQ+E + D
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE---KMHD 568
Query: 122 ASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEE----- 176
+ + + E + E+EEK ++E+ I E E +T+ ++ E+
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEK--IREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 177 ---NKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQE-DKPTFKKEEIKDEK 232
++E+K + +EE+ + + I E + K++ + E +QE ++ +++EE E+
Sbjct: 627 EKMQEQEEKMRRQEEKIREQEKKIREQE-----EKIREQEEMMQEQEEKMWEQEEKMCEQ 681
Query: 233 IKKDKEPKEEVKSFMDRKKGFTEVK-SQNGEFMTHKLKHTE 272
+K +E +E+++ + K EV+ Q E M +H E
Sbjct: 682 EEKMQEQEEKMRR-QEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 36.2 bits (82), Expect = 0.081
Identities = 26/155 (16%), Positives = 62/155 (40%), Gaps = 7/155 (4%)
Query: 27 DEEEAARERRRRA--RQERLRQKQE-----EESLGQVTDQVEVNAQNSVPDEEAKTTTTN 79
D+EE RE+ + ++E++R+++E EE + + + + + EE
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 80 TQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENE 139
E +++ E R +E++ + +E + Q+E + + + + E
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 140 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 174
EK + E + E+ + K + + +A
Sbjct: 688 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 29.6 bits (65), Expect = 7.6
Identities = 21/106 (19%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 11 RSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPD 70
R ++Q ++ + EE+ + + QE ++QEE+ Q + + +
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ---------EKKIRE 652
Query: 71 EEAKTTTTNTQVEGDDEAAF--LERLARREERRQKRLQEALERQKE 114
+E K ++ +E + E++ +EE+ Q++ +E + RQ+E
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ-EEKMRRQEE 697
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 92.4 bits (228), Expect = 1e-18
Identities = 96/401 (23%), Positives = 185/401 (46%), Gaps = 36/401 (8%)
Query: 17 SQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV--NAQNSVPDEEAK 74
+++ QR ++ + ER+RR Q+ L +++ + L + +Q+E N EE
Sbjct: 107 AEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGD 166
Query: 75 TTTTNTQV-------EGDDEAAFLERLARREERRQKRLQEALE-RQKEFDPTITDAS-LS 125
+ T V G + F + REE+ + + +E R +E P++ +A LS
Sbjct: 167 DSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKCLS 226
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
L + +D E+E K+E + + EE E + Q+N + AEE ++ E+E
Sbjct: 227 L----VMDDEIESEA--KKESLSPGKLKLTFEELE---RQRQENRKKQAEEEARKRLEEE 277
Query: 186 EEEEEKPKRGSIGENQGEEKGTKVQA--KREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 243
+ E+ +R + E++ + K+ + KL+ +++ +DEK K ++E + +
Sbjct: 278 KRAFEEARRQMVNEDEENQDTAKIFKGYRPGKLKLSFEEMERQRREDEKRKAEEEARRRI 337
Query: 244 KSFMDRKKGFTEVKSQN--GEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 301
+ + KK F E + + K F PG + ++ +E E +R
Sbjct: 338 E---EEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPG-KLEINFEELLKQKMEEEKRRT 393
Query: 302 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE-------ERRKVLEEEEQRRKQE 354
EE R+ + E E +EFE+L+Q+ E E E RE +R ++ + + K E
Sbjct: 394 EEERKHKLEMEKQEFEQLRQEMGEEEEENETFGLSREYEELIKLKRSGSIQAKNLKSKFE 453
Query: 355 EADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDD 395
+ +L E+E +++++EE RRRA E +++ E+ +D
Sbjct: 454 KIG-QLSEKEIQKKIEEERARRRAIDLEIKEREAENFHEED 493
Score = 87.4 bits (215), Expect = 3e-17
Identities = 117/468 (25%), Positives = 201/468 (42%), Gaps = 76/468 (16%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
QR DE++ +E+ R R+ R+KQE + + D+ +V+++ E+A
Sbjct: 47 QRRSRDEKQRRKEQYIREREWN-RRKQEIKEMLASDDEEDVSSKV----EKAYVPKLTGT 101
Query: 82 VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN--- 138
V+G F E +R+E ++KR +E +R+ E D L R++Q + A+
Sbjct: 102 VKG----RFAEMEKQRQEEQRKRTEEERKRRIEQD--------MLEKRKIQRELAKRAEQ 149
Query: 139 ----ETTEKEEKSESRQERYEIEETETVTKSYQKND--WRDAEENKKEDKEKEEEEEEKP 192
T E SE + I T KSY+ + ++ E+ +KE +EKE + E+
Sbjct: 150 IEDINNTGTESASEEGDDSLLI--TVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEED 207
Query: 193 KRGSIGENQGEEKGTKV-----------QAKREKLQED--KPTFKKEEIKDEKIKKDKEP 239
KR E + K K +AK+E L K TF++ E + ++ +K +
Sbjct: 208 KRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAE 267
Query: 240 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFS-----RPGGRASVDTKEAEGAPQ 294
+E K + K+ F E + Q M ++ + ++T RP G+ + +E E +
Sbjct: 268 EEARKRLEEEKRAFEEARRQ----MVNEDEENQDTAKIFKGYRP-GKLKLSFEEMERQRR 322
Query: 295 VEAGKRLEELRRRRGETESEEFEKLKQKQ-------------QEAALELEELKKKREERR 341
+ ++ EE RRR E E + F + ++ + L +L+ EE
Sbjct: 323 EDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLEINFEELL 382
Query: 342 KVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKC 401
K EEE+RR +EE KL E K+E E+ R E E+ ++ GLS + +
Sbjct: 383 KQKMEEEKRRTEEERKHKLEME------KQEFEQLRQEMGEEEEENETFGLSREYEELIK 436
Query: 402 FTPKGS------SLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSR 443
GS K E+ + K +QK + + AI +I R
Sbjct: 437 LKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDLEIKER 484
Score = 70.1 bits (170), Expect = 5e-12
Identities = 88/371 (23%), Positives = 161/371 (43%), Gaps = 58/371 (15%)
Query: 83 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
+GD + F REER Q+R ++ +R+KE I + +RR Q + +
Sbjct: 28 KGDVKDKFEAMQRAREERNQRRSRDEKQRRKE--QYIREREW---NRRKQEIKEMLASDD 82
Query: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
+E+ S ++ Y + T TV K + + E+ ++E++ K EEE K + I ++
Sbjct: 83 EEDVSSKVEKAYVPKLTGTV-----KGRFAEMEKQRQEEQRKRTEEERKRR---IEQDML 134
Query: 203 EEKGTKVQ---AKREKLQED--------------------------KPTFKKEEIKDEKI 233
E++ K+Q AKR + ED T K + E +
Sbjct: 135 EKR--KIQRELAKRAEQIEDINNTGTESASEEGDDSLLITVVPVKSYKTSGKMKKNFEDL 192
Query: 234 KKDKEPKEEVKSFMDRKKGFTEVKSQNGE------FMTHKLKHTENTFSRPGGRASVDTK 287
+K++E KE +K D++ + E + E M +++ S G+ + +
Sbjct: 193 EKEREEKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFE 252
Query: 288 EAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK---QQEAALELEELKKKREERRKVL 344
E E Q K+ EE R+R E E FE+ +++ + E + ++ K + L
Sbjct: 253 ELERQRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTAKIFKGYRPGKLKL 312
Query: 345 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPF--KCF 402
EE R++ E +++ EEE +RR++EE ++A A +R + +D + K +
Sbjct: 313 SFEEMERQRREDEKRKAEEEARRRIEEE---KKAFAEARRNMVVDDDSPEMYKTISQEFL 369
Query: 403 TPKGSSLKIEE 413
TP + EE
Sbjct: 370 TPGKLEINFEE 380
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/329 (23%), Positives = 134/329 (40%), Gaps = 81/329 (24%)
Query: 149 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTK 208
S++ + ++ V K+Y + ++K E ++ EE NQ + K
Sbjct: 5 SQKAEILLSSSKPVPKTYVPKLGKGDVKDKFEAMQRAREER----------NQRRSRDEK 54
Query: 209 VQAKREKLQEDKPTFKKEEIK------DEKIKKDKEPKEEVKSFMDRKKG-FTEVKSQNG 261
+ K + ++E + +K+EIK DE+ K K V KG F E++ Q
Sbjct: 55 QRRKEQYIREREWNRRKQEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQ 114
Query: 262 EFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE------ 315
E + K TE R + ++ ++ + + +++E++ E+ SEE
Sbjct: 115 E---EQRKRTEEERKRRIEQDMLEKRKIQ-RELAKRAEQIEDINNTGTESASEEGDDSLL 170
Query: 316 ------------------FEKL-KQKQQEAALELEELKKKR-EERRKVLEE--------- 346
FE L K+++++ ++ EE K+ R EE+R L+E
Sbjct: 171 ITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMD 230
Query: 347 ---------------------EEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 385
EE R+++E +K EEE ++RL+EE +RA +RQ
Sbjct: 231 DEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEE---KRAFEEARRQ 287
Query: 386 KMPEDGLSDD-KKPFKCFTPKGSSLKIEE 413
+ ED + D K FK + P L EE
Sbjct: 288 MVNEDEENQDTAKIFKGYRPGKLKLSFEE 316
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/202 (22%), Positives = 83/202 (41%), Gaps = 33/202 (16%)
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTK-EAEGAPQVEAGKRL---EELRRRRGETES 313
SQ E + K T+ G+ V K EA + E +R E+ RR+
Sbjct: 5 SQKAEILLSSSKPVPKTYVPKLGKGDVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIRE 64
Query: 314 EEFEKLKQK---------QQEAALELEEL-----------------KKKREERRKVLEEE 347
E+ + KQ+ +++ + ++E+ K+++EE+RK EEE
Sbjct: 65 REWNRRKQEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEE 124
Query: 348 EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGS 407
+RR +++ K + + E + E+IE E + +D L P K + G
Sbjct: 125 RKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGDDSLLITVVPVKSYKTSG- 183
Query: 408 SLKIEERAEFLNKSVQKSSGVK 429
K+++ E L K ++ +K
Sbjct: 184 --KMKKNFEDLEKEREEKERIK 203
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 91.3 bits (225), Expect = 2e-18
Identities = 106/417 (25%), Positives = 179/417 (42%), Gaps = 24/417 (5%)
Query: 26 DDEEEAARERRRRARQERLRQKQE--EESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVE 83
D EE+ +ER + ++ER ++ +E EE G+ ++ + + E K +VE
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765
Query: 84 GDDEAAFLERLARREER---RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN-- 138
G+ E ER ++EER +K +E + + E + T ++ E
Sbjct: 766 GEREKEEGER--KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 139 -ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
E E+EE+ E +E E EE E + ++ + + EE ++ + E+E EE E
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEE-EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 257
GE +GEE+G + E E + + E ++E K +E EE + + ++G E +
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 317
GE + + G E EG + E G+ E GE E EE E
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEG------EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996
Query: 318 KLKQKQQEAALELE---ELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIE 374
+ +++ E E E E +++ E +V EE + +EE + EE EK EE
Sbjct: 997 EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR 1056
Query: 375 RRRAEAAEKRQKMPEDGLSD----DKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSG 427
R R E E+ K E G + D + +K + S+K + + KSV + G
Sbjct: 1057 RNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQG 1113
Score = 78.6 bits (192), Expect = 1e-14
Identities = 101/431 (23%), Positives = 181/431 (41%), Gaps = 61/431 (14%)
Query: 10 RRSLAALSQ-IAYQRNDDDEE--EAARERRRRARQERLRQ--------------KQEEES 52
++++ L+Q A NDD +E E + + +A ++ + Q EE
Sbjct: 526 QQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVE 585
Query: 53 LGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAF------LERLARREERRQKRLQ 106
+ + + E + N + ++E + N +V G + L A E + K +
Sbjct: 586 IPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVG 645
Query: 107 EALERQK-EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKS 165
EA + + D T + S AE+ E+ EK E + R E+E K
Sbjct: 646 EAEDGPEGRGDGTCEEGSSG----------AEHWQDEEREKGEKDKGRGEMERPGEGEKE 695
Query: 166 Y-QKNDWRDAEENKKEDKEKE-----EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQED 219
+K +W+ + ++E KE+E E +E + G +GEE+ + + EK E
Sbjct: 696 LAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEG 755
Query: 220 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK---------------KGFTEVKSQNGEFM 264
K + EE++ E+ K++ E K+E ++ + K +G E K + GE
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVE 815
Query: 265 THKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ 324
+++ E R + +E EG + E G+ EE +GE E EE E ++ ++
Sbjct: 816 GGEVE--EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Query: 325 ---EAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA 381
E E E + + E + EEE + +EE + + EEE + + +EE E E
Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGE 933
Query: 382 EKR-QKMPEDG 391
E+ + EDG
Sbjct: 934 EEEGEGEGEDG 944
Score = 45.4 bits (106), Expect = 1e-04
Identities = 50/235 (21%), Positives = 95/235 (40%), Gaps = 7/235 (2%)
Query: 25 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 84
+ +EEE E +E + +EEE G+ ++ E + +EE + + + EG
Sbjct: 894 EGEEEEGEGE----GEEEGEGEGEEEEGEGKGEEEGE-EGEGEGEEEEGEGEGEDGEGEG 948
Query: 85 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKE 144
++E E EE + +E +E + + + + E E E
Sbjct: 949 EEEEGEWE--GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 145 EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEE 204
E+ E E E E E + + + EE ++E +E+E+E E + R + E + EE
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 205 KGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 259
+ + E ++D +KK +K K + KS + + E +S+
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121
Score = 43.5 bits (101), Expect = 5e-04
Identities = 70/301 (23%), Positives = 120/301 (39%), Gaps = 53/301 (17%)
Query: 176 ENKKEDKEKEEEEEEKPKRGSIGENQG---EEKGTKVQAKREKLQEDKPTFKKEEIKDEK 232
EN D+ +E E ++ K +QG + T ++A + +E + +KE +D K
Sbjct: 540 ENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSD--EEVEIPEEKEGAEDSK 597
Query: 233 ----IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 288
+++ E EE +K TE+ S + +T K + +E G + D E
Sbjct: 598 GNGIEEQEVEANEENVKVHGGRKEKTEILSDD---LTDKAEVSEGKAKSVG--EAEDGPE 652
Query: 289 AEGAPQVEAG----KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL 344
G E G + ++ R +GE + E + + E L +E KKR+ +
Sbjct: 653 GRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQ 712
Query: 345 EEEEQRR-------------------KQEEADRKLREEE-------------EKRRLKEE 372
+E EQ ++EE DR+ EE+ E R KEE
Sbjct: 713 KEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772
Query: 373 IERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTH 432
ER++ E A K +K E+G D+ + +G + EE E V++ G +
Sbjct: 773 GERKKEERAGKEEKGEEEG---DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 433 Q 433
+
Sbjct: 830 E 830
Score = 40.4 bits (93), Expect = 0.004
Identities = 50/243 (20%), Positives = 90/243 (37%), Gaps = 14/243 (5%)
Query: 25 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 84
++ E E E +E K EEE + E + D E + + EG
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957
Query: 85 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKE 144
++E E E ++ E E + E + + + E E E+E
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Query: 145 E-----KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE---------EE 190
E + E + E EE E + ++ + EEN++ +E+EEEE E
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEEN 1077
Query: 191 KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 250
+ + G + + KG+ K + Q+ T + K+++ K + K +K+
Sbjct: 1078 ERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPSGS 1137
Query: 251 KGF 253
K F
Sbjct: 1138 KKF 1140
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 90.1 bits (222), Expect = 5e-18
Identities = 104/479 (21%), Positives = 217/479 (45%), Gaps = 59/479 (12%)
Query: 15 ALSQIAYQRNDDDEE-----EAARERRRRARQER---------LRQKQEEESLGQVTDQV 60
ALS Y+ DEE +E+ R E+ L++K E L Q+
Sbjct: 201 ALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQL 260
Query: 61 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE---RRQKRLQEALERQKEFDP 117
+V A + ++ + QVE ++ L + ++EE R+++++QE E+ E +
Sbjct: 261 QVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKIQEQEEKMCEQEL 318
Query: 118 TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN 177
I + + + + E + E+E+K ++E+ I E E + ++ WR E+
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK--IREQEEKIREQEEKMWRQEEKI 376
Query: 178 KKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 237
+++D++ +E+EEE ++ Q E++ K+ + +K++E +++E +E ++++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE--EEMWRQEE 434
Query: 238 EPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEA 297
+ +E + D+++ EV+ + E K++ E R +E + Q E
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQE-EEEKMQEQEEKIQR---------QEEKIQEQEEK 484
Query: 298 GKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE--- 354
R E+L ++ E + E E+ +Q+E E EE K +E+ K+ +EE+ R+QE
Sbjct: 485 TWRQEKLLKQ--EEKIWEQEEKMWRQEEKMWEQEE--KMQEQEEKMQRQEEKMREQEVRL 540
Query: 355 -EADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEE 413
+ + K++E+E + +E+E R + +K + + G + TP L++E
Sbjct: 541 WQQEEKMQEQEVR---LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTP---ILQVEL 594
Query: 414 RAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAE 472
+++ Q+ + L+QY +A + S K P+ S + A+
Sbjct: 595 KSQEAQSLQQQQDHYR------------GHLQQYVAAYQQLASGKEALPSCSSRKLRAK 641
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 89.0 bits (219), Expect = 1e-17
Identities = 94/436 (21%), Positives = 203/436 (46%), Gaps = 45/436 (10%)
Query: 44 LRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE---R 100
L++K E L Q++V A + ++ + QVE ++ L + ++EE R
Sbjct: 244 LKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWR 301
Query: 101 RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETE 160
+++++QE E+ E + I + + + + E + E+E+K ++E+ I E E
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK--IREQE 359
Query: 161 TVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDK 220
+ ++ WR E+ +++D++ +E+EEE ++ Q E++ K+ + +K++E
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 221 PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGG 280
+++E +E +++++ +E + D+++ EV+ + E K++ E R
Sbjct: 420 EKIREQE--EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE-EEEKMQEQEEKIQR--- 473
Query: 281 RASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER 340
+E + Q E R E+L ++ E + E E+ +Q+E E EE K +E+
Sbjct: 474 ------QEEKIQEQEEKTWRQEKLLKQ--EEKIWEQEEKMWRQEEKMWEQEE--KMQEQE 523
Query: 341 RKVLEEEEQRRKQE----EADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 396
K+ +EE+ R+QE + + K++E+E + +E+E R + +K + + G
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVR---LQELEERLGKLGQKAELLGGAGRESGS 580
Query: 397 KPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKS 456
+ TP L++E +++ Q+ + L+QY +A + S
Sbjct: 581 QRLPTLTP---ILQVELKSQEAQSLQQQQDHYR------------GHLQQYVAAYQQLAS 625
Query: 457 AKPTKPAASDLPVPAE 472
K P+ S + A+
Sbjct: 626 GKEALPSCSSRKLRAK 641
Score = 64.7 bits (156), Expect = 2e-10
Identities = 66/320 (20%), Positives = 150/320 (46%), Gaps = 21/320 (6%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 87
+EE +E+ + ++ L+ +++EE + + +++ + + ++E K ++ +E
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH-EQEEKIREQEDKMWRQEEKIREQEE 360
Query: 88 --AAFLERLARREER---RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTE 142
E++ R+EE+ + +++QE E + I + + + + E E
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 143 K--EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 200
K E++ E ++ +I E E + + Q+ R+ EE +E++EK +E+EEK +R
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQD-QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 201 QGEEK---GTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGF 253
+ EEK K+ + EK+ E + ++E K +EK+++ +E + + M ++
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR 539
Query: 254 TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR-RRGETE 312
+ + + +L+ E + G +A + GA + +RL L + E +
Sbjct: 540 LWQQEEKMQEQEVRLQELEERLGKLGQKAEL----LGGAGRESGSQRLPTLTPILQVELK 595
Query: 313 SEEFEKLKQKQQEAALELEE 332
S+E + L+Q+Q L++
Sbjct: 596 SQEAQSLQQQQDHYRGHLQQ 615
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/383 (21%), Positives = 165/383 (43%), Gaps = 49/383 (12%)
Query: 28 EEEAARERRRRARQERLRQ----------KQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
E EA E R+R +R + KQ +ESL +VT ++PD+EA
Sbjct: 68 EMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTF--------TLPDDEAIEDA 119
Query: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
+ V+ + + + +KR ++ E+ F + + P R+ TA+
Sbjct: 120 GVSHVKKNSDEV--------KSSFKKRQEKMNEKNYTFRKRVV---IKKPWLRLGEVTAQ 168
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE--ENKKEDKEKEEEEEEKPKRG 195
E E+ + + + K ++ D E N D+E +E+ E ++
Sbjct: 169 KRP-ENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKL 227
Query: 196 SIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 255
+ E++ E V+ + KL+ + +++++ E + KE + V + + + E
Sbjct: 228 RLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE-LQSVSAKLQAQVEENE 286
Query: 256 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 315
+ + + K+ E + +E + Q + EE R+ E E+
Sbjct: 287 LWNLLNQQQEEKMWRQEE---------KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
Query: 316 FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIE 374
EK+++++ + + E++ RE+ K+ E+EE+ +QEE K+RE++EK + +EE+
Sbjct: 338 EEKIREQEDKMWRQEEKI---REQEEKIREQEEKMWRQEE---KIREQDEKIQEQEEEMW 391
Query: 375 RRRAEAAEKRQKMPEDGLSDDKK 397
R+ + E+ +K E +KK
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKK 414
Score = 41.2 bits (95), Expect = 0.003
Identities = 36/186 (19%), Positives = 82/186 (44%), Gaps = 31/186 (16%)
Query: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 85
+ EEE R+ + E + Q QEE+ L +V ++++ + + ++E K +++
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEK-LREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQ 481
Query: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 145
+E + + ++E + +E + RQ+E + E+EE
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEE------------------------KMWEQEE 517
Query: 146 KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGE---NQG 202
K + ++E+ + +E + + + W+ E+ ++++ +E EE K G E G
Sbjct: 518 KMQEQEEKMQRQEEK--MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAG 575
Query: 203 EEKGTK 208
E G++
Sbjct: 576 RESGSQ 581
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 88.6 bits (218), Expect = 1e-17
Identities = 79/361 (21%), Positives = 168/361 (46%), Gaps = 28/361 (7%)
Query: 59 QVEVNAQNSVPDEEAKTTTTNTQVEGDD-----EAAFLERLARREERRQKRLQEALERQK 113
++E + ++ + E +K T+ ++E + E +E+ R ER ++R +E ER++
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 114 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 173
E + R + D + T E++ + ++R E +S +N R
Sbjct: 328 EREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE-----RSSDRNKDRS 382
Query: 174 AEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKD--E 231
K D+E+E E E + +R E + E + + + + + ++DK ++E+ +D E
Sbjct: 383 RSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYE 442
Query: 232 KIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA-- 289
+ K +++ +E+ ++ +R K + E++ + K E R + + KE
Sbjct: 443 RRKLERKLREKEAAYQERLKNW-EIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501
Query: 290 -----EGAPQVEAGKRLEE-LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 343
P+ G L++ LR R E E++E ++ ++K+ ELEE++++
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE-----ELEEIRQRLLAEGHP 556
Query: 344 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFT 403
+ E +R ++EA+R+ + + ++ EE E + E EKR++ E+ ++KP C
Sbjct: 557 DPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP--CLK 614
Query: 404 P 404
P
Sbjct: 615 P 615
Score = 77.0 bits (188), Expect = 4e-14
Identities = 85/375 (22%), Positives = 160/375 (42%), Gaps = 38/375 (10%)
Query: 59 QVEVNAQNSVPDEEAKTTTTNTQ-----VEGDDEAAFLERLARREERRQKRLQEALERQK 113
+V+ + + + +AK +N V DDE A E RR++ + ++ +
Sbjct: 160 KVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYS 219
Query: 114 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEI-----------EETETV 162
+ L+ PS+ ++ + +K+EK E R+ + E+ +
Sbjct: 220 --------SELNAPSQ----ESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAI 267
Query: 163 TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPT 222
K D E +K D K+ EEE+ K E + E + + + +RE+ + ++
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 223 FKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRA 282
++ E + EK +K++E + E DR K + + + + + ++ R R
Sbjct: 328 EREREREREK-EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386
Query: 283 SVDTKEAEGAPQVEAGKRLEELRRRRGETESE---EFEKLKQKQQEAALELEELKKKREE 339
+E E + E + E R R E E E E E+ K K+++ + E+ ++R+
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKL 446
Query: 340 RRKVLEEE----EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDD 395
RK+ E+E E+ + E +RK E EK +EE RR KR K + DD
Sbjct: 447 ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD 506
Query: 396 KKPFKCFTPKGSSLK 410
+ K + +GS+L+
Sbjct: 507 RDDPKYY--RGSALQ 519
Score = 75.5 bits (184), Expect = 1e-13
Identities = 78/332 (23%), Positives = 137/332 (41%), Gaps = 51/332 (15%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
+R + E E RER + +ER R++ + + D+ ++ D E + +
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR 381
Query: 82 VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
+++ ER RE R++ + ER++E + R + + +++
Sbjct: 382 SRSREKSRDRERERERERERERERERERERERERE----------REREREREREKDKKR 431
Query: 142 EKEEKSESRQERYEIE----ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
++EE E ER ++E E E + KN W E K + EKE E EE+ +R
Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKN-WEIRERKKTREYEKEAEREEERRR--- 487
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 257
E E K K + D P + + +++ +D+E KE DRK+ E++
Sbjct: 488 -EMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRL-RDRE-KEMEADERDRKREKEELE 544
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 317
+ AEG P +A EL+R E E
Sbjct: 545 EIRQRLL------------------------AEGHPDPDA-----ELQRMEQEAERRRQP 575
Query: 318 KLKQKQQEAALELEELKKKREERRKVLEEEEQ 349
++KQ + E+ E EE ++K E+R + +EEEE+
Sbjct: 576 QIKQ-EPESEEEEEEKQEKEEKREEPMEEEEE 606
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 87.0 bits (214), Expect = 4e-17
Identities = 101/436 (23%), Positives = 201/436 (46%), Gaps = 50/436 (11%)
Query: 28 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEE--AKTTTTNTQVEG- 84
+E+ ++ + + ++E+ +Q +E+ + + +++ + AQ D E A T N + E
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 85 ----------------DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPS 128
DD + E L ++ + +K + +E D D LP
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDS--EELEDKDSKSKKTAKPKVEMYSGSDDD--DDFNKLPK 148
Query: 129 RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE 188
+ N+ + E+ E ++ I+E + S + D +++E + K +++ +
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKK--IKERSRINSSGESGD--ESDEFLQSRKGQKKNQ 204
Query: 189 EEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE-KIKKDKEPKEEVKSFM 247
+ KP N+ ++ K++ +K E K +K+ +++ K++K KE KEE+++
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE-KEELET-- 261
Query: 248 DRKKGFTEVKSQNGEFM--THKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 305
KK ++ K +F T K K T +T P +T A E K+ ++ +
Sbjct: 262 -GKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTA-AEDDNEGDKKKKDKK 319
Query: 306 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR--KLREE 363
+++GE E +E EK K + ++E K L+EEE+R+K+EE +R +L E
Sbjct: 320 KKKGEKEEKEKEKKKGPSKATVKAMQEALAK-------LKEEEERQKREEEERIKRLEEL 372
Query: 364 EEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 423
E KR+ +E +E+ + E ++++K ++ L KK K T S + RAE K +Q
Sbjct: 373 EAKRKEEERLEQEKRERKKQKEKERKERL---KKEGKLLTK--SQREARARAEATLKLLQ 427
Query: 424 KSSGVKSTHQAAIVSK 439
+ GV+ + ++ K
Sbjct: 428 -AQGVEVPSKDSLPKK 442
Score = 74.7 bits (182), Expect = 2e-13
Identities = 97/460 (21%), Positives = 193/460 (41%), Gaps = 88/460 (19%)
Query: 21 YQRNDDDEEEAARERRRRARQERLRQK-----QEEESLGQVTDQVEVNAQNSVPDE---- 71
Y +DDD++ ++ + + ++ +K ++E++ ++ ++ +N+ DE
Sbjct: 134 YSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEF 193
Query: 72 --------EAKTTTTNTQVEG---DDEAAF-----LERLARREERRQKRLQEA------L 109
+ + +E DD+A+F ++ A ++ER +K+ E L
Sbjct: 194 LQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKL 253
Query: 110 ERQKEFDPTITDASLSLPS-RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 168
+ ++E + D S S R+ + +T +++ T + +E+ ET T + +
Sbjct: 254 KEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEK---AETPTAAEDDNE 310
Query: 169 NDWRDAEENKK--EDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKE 226
D + ++ KK E +EKE+E+++ P + ++ Q K + +R+K +E++ + E
Sbjct: 311 GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE 370
Query: 227 EI--------------KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM----THKL 268
E+ ++ K +K+KE KE +K K+G KSQ T KL
Sbjct: 371 ELEAKRKEEERLEQEKRERKKQKEKERKERLK-----KEGKLLTKSQREARARAEATLKL 425
Query: 269 KHTENTF-----SRPGGRASVDTKEAEGAPQVEAGKRLEELRR-------------RRGE 310
+ S P R + K+ + PQ K + E + E
Sbjct: 426 LQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEE 485
Query: 311 T-------ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 363
T E E+ E EA EE +K + + +E ++EE + + +E
Sbjct: 486 TPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDE 545
Query: 364 EEKRRLKEEIERRRAEAAEKRQKMPED---GLSDDKKPFK 400
E + +EE E +E E+ +K+ ++ G + DKKP K
Sbjct: 546 ESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Score = 70.9 bits (172), Expect = 3e-12
Identities = 78/394 (19%), Positives = 166/394 (42%), Gaps = 58/394 (14%)
Query: 22 QRNDDDEEEAA------RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
+R DEE+A +E ++++ +QK+ + + T + +V V +
Sbjct: 239 ERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEK 298
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 135
T T E D+E +++++++K +E E++K+ P+ + MQ
Sbjct: 299 AETPTAAEDDNEGD----KKKKDKKKKKGEKEEKEKEKKKGPSKATV------KAMQEAL 348
Query: 136 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 195
A+ + E+ +K E + +EE E K ++ + E K+++KE++E +++ K
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 196 SIGENQG-----------EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 244
+ + + + +G +V +K + L + +P + E+ K +KI + E KE +
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSK-DSLPKKRPIY--EDKKRKKIPQQLESKEVSE 465
Query: 245 SFM-------------DRKKGFTEVKSQNGEFMT-------HKLKHTENTFSRPGGRASV 284
S ++++ V+ + E + E T G + +
Sbjct: 466 SMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHI 525
Query: 285 DTKE-----AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK---QQEAALELEELKKK 336
+ KE E + E + EE GE+E E ++ +K ++++ L++ K
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Query: 337 REERRKVLEEEEQRRKQEEADRKLREEEEKRRLK 370
+ ++ R K+E A K + EKRRL+
Sbjct: 586 EMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLE 619
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/259 (22%), Positives = 122/259 (47%), Gaps = 25/259 (9%)
Query: 27 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDD 86
+EE +E+R R +Q+ +K+ + G++ + + A+ A+ T Q +G
Sbjct: 378 EEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREAR-----ARAEATLKLLQAQGV- 431
Query: 87 EAAFLERLARR----EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT- 141
E + L ++ E++++K++ + LE ++ + A++ + M+ E E T
Sbjct: 432 EVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEV----MEQGVPEKEETP 487
Query: 142 ------EKEEKSESRQERYEIEETETVTKSYQKNDWR-DAEENKKEDKEKEEEEEEKPKR 194
E+E+ ++ + +E ++ T+ + N + +EN +E++E+EEEEEE +
Sbjct: 488 PPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 195 GSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT 254
E +GE +G++ + EK+ ++K + K D+K K+ E S DR K
Sbjct: 548 EEEEEEEGESEGSEGDEEDEKVSDEKDSGK---TLDKKPSKEMSSDSEYDSDDDRTKEER 604
Query: 255 EVKSQNGEFMTHKLKHTEN 273
+L+H++N
Sbjct: 605 AYDKAKRRIEKRRLEHSKN 623
Score = 46.6 bits (109), Expect = 6e-05
Identities = 69/310 (22%), Positives = 128/310 (41%), Gaps = 56/310 (18%)
Query: 175 EENKKEDKEKEEEEEE---KPKRGSIGENQGEEKGTKVQAKREKLQED------------ 219
++NK ED K++ + + G+ + E + +K + K+EK ++D
Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE 64
Query: 220 -----------------KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 262
KPT EE K KK K K + +SF D E K +
Sbjct: 65 LSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSK 124
Query: 263 FMTHKLK-------HTENTFS----RPGGRASVDTKEAEGAPQVE-AGKRLEELRR--RR 308
T K K ++ F+ + G+A K+ +G+ + E K+++E R
Sbjct: 125 -KTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSS 183
Query: 309 GET--ESEEF-----EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 361
GE+ ES+EF + K ++ + +E + + K+ +++ +++E +RK R
Sbjct: 184 GESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKR 243
Query: 362 EEEEK--RRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLN 419
+EE+ R+LKE+ E + + +QK + ++ K G EE+AE
Sbjct: 244 DEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPT 303
Query: 420 KSVQKSSGVK 429
+ + G K
Sbjct: 304 AAEDDNEGDK 313
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/277 (19%), Positives = 113/277 (40%), Gaps = 23/277 (8%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQ-VEVNAQNSVPD-----EEAKT 75
Q+ + +E +E + + +R + + E +L + Q VEV +++S+P E+ K
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 135
Q+E + + +E A E +++ + ++E P + +D
Sbjct: 452 KKIPQQLESKEVSESMELCAAVEV-----MEQGVPEKEETPPPVEPEEEEDTEDAGLDDW 506
Query: 136 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE------EEEE 189
+ E+ EK E + E++E + ++ + D E ++E++E E +EE+
Sbjct: 507 EAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
Query: 190 EKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR 249
EK ++K +K + + D K+E D+ ++ ++ + E ++
Sbjct: 567 EKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNT 626
Query: 250 KKGFTEVKSQNGEFMT------HKLKHTENTFSRPGG 280
+K + G T KL+HT GG
Sbjct: 627 EKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGG 663
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 85.1 bits (209), Expect = 2e-16
Identities = 81/332 (24%), Positives = 151/332 (45%), Gaps = 28/332 (8%)
Query: 66 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE----RRQKRLQEALERQKEFDPTITD 121
NS P+ + ++ T G EA + RE RR++ ++A+ E + + D
Sbjct: 410 NSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDE-EQHLED 468
Query: 122 ASLSLPSRRMQNDTAENETTEKEEKS--ESRQERYEIEETETVTKSYQKNDWRDAEENKK 179
L P + + + ++ + Q + + +S K+ + +
Sbjct: 469 EELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM 528
Query: 180 EDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK---DEKIKKD 236
+ KEKE + E +R E Q +R+K++EDK + EE+K +E+++K
Sbjct: 529 DPKEKERQRLENLRRKEEAE----------QLRRQKVEEDKRR-RLEEVKLKREERLRKV 577
Query: 237 KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVE 296
+ +E V+ + KK E K + T K K E + + K+ E +VE
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKME---EVE 632
Query: 297 AGKRLEELRRRRGETESEEFEKLKQK--QQEAALELEELKKKREERRKVLEEEEQRRKQE 354
A ++ EE RR + EE E+ Q+ Q++ E E L+K E +R + E++RR+QE
Sbjct: 633 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692
Query: 355 EADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
+++ RE+E + + + E ER+ AE +R++
Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQ 724
Score = 72.0 bits (175), Expect = 1e-12
Identities = 72/264 (27%), Positives = 127/264 (48%), Gaps = 29/264 (10%)
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
L + R + + + + EE R E +++ E + K Q R+ E KE+K+K+
Sbjct: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA---RERVEQMKEEKKKQ 594
Query: 186 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 245
E++ Q +EK K AK E+L E+K K K E+++ ++ +EE +
Sbjct: 595 IEQKFA---------QIDEKTEK--AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
Query: 246 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS--VDTKEAEGAPQVEAGKRLEE 303
++ E + Q + K K E R A + +E E Q +R E+
Sbjct: 644 LRWLQQEEEERRHQE---LLQKKKEEEQERLRKAAEAKRLAEQREQERREQ----ERREQ 696
Query: 304 LRRRRGETESEEFEKLKQ-KQQEAALELEELKKKRE--ERRKVLEEEEQRRKQEEADRKL 360
RR + E E E+ +Q +QE E E L+ +RE ER K L ++++ ++E ++K
Sbjct: 697 ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 756
Query: 361 REEEEK---RRLKEEIERRRAEAA 381
+EE+++ R+L+EE E++ EAA
Sbjct: 757 KEEQQRLAERQLQEEQEKKAKEAA 780
Score = 68.6 bits (166), Expect = 1e-11
Identities = 64/271 (23%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 184
S P M++ N + K + RQ + E + ++ D +E K K
Sbjct: 510 SAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK 569
Query: 185 EEEEEEKPKRGSIG-ENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK--E 241
EE K + E EEK +++ K ++ E K+E + +EK KK K E
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 242 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 301
EV++ R+K E + + + + + ++A A ++ +
Sbjct: 630 EVEA---RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Query: 302 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERR-----KVLEEEEQRRKQ-EE 355
E + R E E E E+ +Q+++E +L E +++RE+ R ++ E E+ R Q E+
Sbjct: 687 ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ 746
Query: 356 ADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
R+L E+++K + ER+ E EK+ K
Sbjct: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/214 (22%), Positives = 105/214 (49%), Gaps = 22/214 (10%)
Query: 32 ARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFL 91
ARER + ++E+ +KQ E+ Q+ ++ E + + +E+AK ++E +
Sbjct: 580 ARERVEQMKEEK--KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 92 ERLARR-----EERRQKRLQEALERQKEFDPTITD--ASLSLPSRRMQNDTAENETTEKE 144
E ARR +E ++R QE L+++KE + A + + + + E E E+E
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
Query: 145 EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEE 204
+ + R+E+ E+ + AE+ ++ ++E+ + E E +R Q E+
Sbjct: 698 RREQERREQERREQERQL-----------AEQERRREQERLQAERELQEREKALRLQKEQ 746
Query: 205 KGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE 238
+++ K++K E++ + ++++E+ KK KE
Sbjct: 747 LQRELEEKKKK--EEQQRLAERQLQEEQEKKAKE 778
Score = 60.8 bits (146), Expect = 3e-09
Identities = 78/354 (22%), Positives = 141/354 (39%), Gaps = 41/354 (11%)
Query: 89 AFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET-----TEK 143
++LERL E QK E E +E +P + A +P N N+T T
Sbjct: 357 SYLERLLNVEVP-QKVGSEQKEPPEEAEP-VAAAEPEVPENNGNNSWPHNDTEIANSTPN 414
Query: 144 EEKSESRQERYEIEETETVT-----------KSYQKNDWRDAEENKKEDKEKEEEEEEKP 192
+ + S E + E T + +K ++ A E++ E+EE + P
Sbjct: 415 PKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPP 474
Query: 193 KRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE-PKEEVKSFMDRKK 251
+ K K+ TF +++ + P+ +KSF+ R
Sbjct: 475 R----------SKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNT 524
Query: 252 GFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGET 311
+ L+ E + D + +++ +RL ++ + R
Sbjct: 525 PLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERV 584
Query: 312 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK-----QEEADRKLREEEEK 366
E + EK KQ +Q+ A E+ +K +EER L EE+ ++K EE + + ++EEE
Sbjct: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEER---LAEEKAKKKAAAKKMEEVEARRKQEEEA 641
Query: 367 RRLK----EEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAE 416
RRL+ EE ERR E +K+++ ++ L + + + + +ER E
Sbjct: 642 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 695
Score = 47.0 bits (110), Expect = 5e-05
Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 48/363 (13%)
Query: 128 SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEE 187
SRR+ TAE S ER E S QK +AE E E
Sbjct: 336 SRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAA----EPE 391
Query: 188 EEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM 247
E S N E + K + P+ ++E K ++ +EP + +
Sbjct: 392 VPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSAR--- 448
Query: 248 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR-LEELRR 306
RK+ + + S+ E +H E+ +P R+ + + V + L ++R
Sbjct: 449 -RKRSYKQAVSELDEE-----QHLEDEELQPP-RSKTPSSPCPASKVVRPLRTFLHTVQR 501
Query: 307 RR-----GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE-EADR-- 358
+ + ++ ++ +E +++R E + EE EQ R+Q+ E D+
Sbjct: 502 NQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRR 561
Query: 359 -----KLREEEEKRRL--------------KEEIERRRAEAAEKRQKMPEDGLSDDKKPF 399
KL+ EE R++ K++IE++ A+ EK +K E+ L+++K
Sbjct: 562 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 621
Query: 400 KCFTPKGSSL----KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTK 455
K K + K EE A L Q+ + HQ + K + E+ A E +
Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEE--ERRHQELLQKKKEEEQERLRKAAEAKR 679
Query: 456 SAK 458
A+
Sbjct: 680 LAE 682
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/137 (21%), Positives = 62/137 (45%), Gaps = 11/137 (8%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
Q ++ + ++++ QERLR+ E + L + +Q + ++E + Q
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQ 706
Query: 82 VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
+ E E+ RRE+ R + +E ER+K +L L ++Q + E +
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREK---------ALRLQKEQLQRELEEKKKK 757
Query: 142 EKEEKSESRQERYEIEE 158
E++++ RQ + E E+
Sbjct: 758 EEQQRLAERQLQEEQEK 774
Score = 38.9 bits (89), Expect = 0.013
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 10/131 (7%)
Query: 11 RSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEE----SLGQVTDQVEVNAQN 66
R A ++A QR + E+ RE+ RR ++ R ++++E+E + +Q + A+
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731
Query: 67 SVPDEEAKTTTTNTQVEGDDE----AAFLERLARR--EERRQKRLQEALERQKEFDPTIT 120
+ + E Q++ + E +RLA R +E ++K+ +EA K + T+
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVD 791
Query: 121 DASLSLPSRRM 131
S + S +M
Sbjct: 792 VQSPACTSYQM 802
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 84.3 bits (207), Expect = 3e-16
Identities = 62/212 (29%), Positives = 110/212 (51%), Gaps = 29/212 (13%)
Query: 178 KKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 237
+ E +E+E E E + + G+ + E + K + +REK + ++ +K E + +K KK +
Sbjct: 35 QSEIREREREIETRKE----GKKERESERKKERREREKRKREREKERKRE-RGKKEKKGE 89
Query: 238 EPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEA 297
KEE +RKK E +++ GE + K + + GR S + KE
Sbjct: 90 RKKEE----RERKKRRREKENKEGEEKEKRKKKEK----KERGRTSKEGKE--------- 132
Query: 298 GKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEAD 357
R R+ E + EE ++ ++K++E E E ++K+ ER++V E+EE+R+++E +
Sbjct: 133 -------RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 358 RKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 389
RK RE K R KE + R E ++R+K E
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKEE 217
Score = 75.5 bits (184), Expect = 1e-13
Identities = 64/249 (25%), Positives = 125/249 (50%), Gaps = 38/249 (15%)
Query: 137 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 196
++E E+E + E+R+E + E+E R E ++E +++E E+E K +RG
Sbjct: 35 QSEIREREREIETRKEGKKERESE-----------RKKERREREKRKREREKERKRERG- 82
Query: 197 IGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
+ E+KG + + +RE+ + + KE + EK KK KE KE ++ + K+ +
Sbjct: 83 ----KKEKKGERKKEERERKKRRREKENKEGEEKEKRKK-KEKKERGRTSKEGKERERKE 137
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316
+ + E R + K+ E + E +R + R++ GE E E
Sbjct: 138 ERKREE------------------RKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 317 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERR 376
EK ++++++ +E KK+RE RK E ++ RK++E +K R+++ + +E+ ER
Sbjct: 180 EKERKERKKRERNRKERKKERE--RKERRERKKERKKKEERKKERQKDRQTNWREK-ERG 236
Query: 377 RAEAAEKRQ 385
+ E E+++
Sbjct: 237 KRERKERKK 245
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/163 (30%), Positives = 88/163 (53%), Gaps = 6/163 (3%)
Query: 92 ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ 151
ER R+ ER ++R +E +++K+ + + RR + + E E EK +K E ++
Sbjct: 65 EREKRKREREKERKRERGKKEKKGERKKEERERK--KRRREKENKEGEEKEKRKKKEKKE 122
Query: 152 E-RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK--RGSIGENQGEEKGTK 208
R E E K +K + R E KKE++EKE E +E+ K R +GE + EE+ K
Sbjct: 123 RGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE-EERKEK 181
Query: 209 VQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKK 251
+ +R+K + ++ KKE + E+ ++ KE K++ + +R+K
Sbjct: 182 ERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Score = 67.4 bits (163), Expect = 3e-11
Identities = 59/266 (22%), Positives = 115/266 (43%), Gaps = 51/266 (19%)
Query: 112 QKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW 171
Q + I + + +R+ E+E ++ + E R+ E E K +K +
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 172 RDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE 231
+ E +K+ + ++E +E GE + + K + + + +E K +KEE K E
Sbjct: 91 KKEERERKKRRREKENKE--------GEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 232 KIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG 291
+ K+ + KEE + +RK+ + Q GE KE E
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGE------------------------KEEE- 177
Query: 292 APQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRR 351
R E+ R+ R + E E+ K+++ +K+R ER+K +++E+R+
Sbjct: 178 --------RKEKERKERKKRERNRKERKKERE----------RKERRERKKERKKKEERK 219
Query: 352 KQEEADRKLREEEEKRRLKEEIERRR 377
K+ + DR+ E++R +E ER++
Sbjct: 220 KERQKDRQTNWREKERGKRERKERKK 245
Score = 66.2 bits (160), Expect = 7e-11
Identities = 58/233 (24%), Positives = 101/233 (43%), Gaps = 37/233 (15%)
Query: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
+I ++ E E+ R++ RR R++R R++++E K
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKER----------------------KRER 81
Query: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
+ +G+ + ER RR E+ K +E +R+K+ S R + +
Sbjct: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
E E+E K E R E E K +K + + E ++E KEKE +E +K +R
Sbjct: 142 EERKERERKKEER-------EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR- 193
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKD------EKIKKDKEPKEEVK 244
+ + +E+ K + +R+K ++ K KKE KD EK + +E KE K
Sbjct: 194 -KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 62.4 bits (150), Expect = 1e-09
Identities = 48/175 (27%), Positives = 77/175 (44%), Gaps = 10/175 (5%)
Query: 260 NGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE----------ELRRRRG 309
N E H ++PG ++ + +E E + E K E E R+R
Sbjct: 14 NTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKRER 73
Query: 310 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 369
E E + K+K+ E E E KK+R E+ EE+++RK++E + R +E +
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 370 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQK 424
+ + ER+R E E+ +K E ++K K K K EER E K +K
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188
Score = 62.0 bits (149), Expect = 1e-09
Identities = 69/265 (26%), Positives = 113/265 (42%), Gaps = 68/265 (25%)
Query: 80 TQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENE 139
T+ EG E + RRE ++KR +E ER++E R + E +
Sbjct: 47 TRKEGKKERESERKKERREREKRKREREK-ERKRE--------------RGKKEKKGERK 91
Query: 140 TTEKEEKSESRQ-ERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 198
E+E K R+ E E EE E K +K R ++E K+ ++++E + EE+ +R
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 199 ENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKS 258
E + +E+ K + KRE+ Q + K+EE +K+KE KE K +RK+
Sbjct: 152 EEREKERERKERKKRERKQVGE---KEEE------RKEKERKERKKRERNRKE------- 195
Query: 259 QNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEK 318
KE E R E R++ + EE +K
Sbjct: 196 --------------------------RKKERE---------RKERRERKKERKKKEERKK 220
Query: 319 LKQKQQEAA-LELEELKKKREERRK 342
+QK ++ E E K++R+ER+K
Sbjct: 221 ERQKDRQTNWREKERGKRERKERKK 245
Score = 57.4 bits (137), Expect = 3e-08
Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 9/153 (5%)
Query: 254 TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES 313
+E++ + E T K E R R + ++ E + + + +E + R + E
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 314 EEFEKLKQKQQEAALELEELKKKREERR-------KVLEEEEQRRKQE--EADRKLREEE 364
E ++ ++K+ + E E+ KKK ++ R K E +E+R+++E E +RK E E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 365 EKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 397
++R KE +R R + EK ++ E + KK
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKK 188
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 82.8 bits (203), Expect = 8e-16
Identities = 86/336 (25%), Positives = 153/336 (45%), Gaps = 32/336 (9%)
Query: 66 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE----RRQKRLQEALERQKEFDPTITD 121
NS P+ + ++ T G EA + RE RR++ ++A+ E + + D
Sbjct: 410 NSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDE-EQHLED 468
Query: 122 ASLSLP-SRRMQNDTAENETTEKEEKSESRQERYEIEETET-----VTKSYQKNDWRDAE 175
L P S+ + ++ +R ++ T T V KS+ K +
Sbjct: 469 EELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM 528
Query: 176 ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIK---DEK 232
+ K EKE + E +R E Q +R+K++EDK + EE+K +E+
Sbjct: 529 DPKCSFVEKERQRLENLRRKEEAE----------QLRRQKVEEDKRR-RLEEVKLKREER 577
Query: 233 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 292
++K + +E V+ + KK E K + T K K E + + K+ E
Sbjct: 578 LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKME-- 633
Query: 293 PQVEAGKRLEELRRRRGETESEEFEKLKQK--QQEAALELEELKKKREERRKVLEEEEQR 350
+VEA ++ EE RR + EE E+ Q+ Q++ E E L+K E +R + E++R
Sbjct: 634 -EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 692
Query: 351 RKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
R+QE +++ RE+E + + + E ER+ AE +R++
Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQ 728
Score = 74.3 bits (181), Expect = 3e-13
Identities = 84/312 (26%), Positives = 141/312 (45%), Gaps = 59/312 (18%)
Query: 79 NTQVEGDDEAAFLERLARR-EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
NT + D + +F+E+ +R E R+K E L RQK
Sbjct: 523 NTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKV----------------------- 559
Query: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
EE R E +++ E + K Q R+ E KE+K+K+ E++
Sbjct: 560 ------EEDKRRRLEEVKLKREERLRKVLQA---RERVEQMKEEKKKQIEQKFA------ 604
Query: 198 GENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 257
Q +EK K AK E+L E+K K K E+++ ++ +EE + ++ E +
Sbjct: 605 ---QIDEKTEK--AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 258 SQNGEFMTHKLKHTENTFSRPGGRAS--VDTKEAEGAPQVEAGKRLEELRRRRGETESEE 315
Q + K K E R A + +E E Q +R E+ RR + E E
Sbjct: 660 HQE---LLQKKKEEEQERLRKAAEAKRLAEQREQERREQ----ERREQERREQERREQER 712
Query: 316 FEKLKQ-KQQEAALELEELKKKRE--ERRKVLEEEEQRRKQEEADRKLREEEEK---RRL 369
E+ +Q +QE E E L+ +RE ER K L ++++ ++E ++K +EE+++ R+L
Sbjct: 713 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 772
Query: 370 KEEIERRRAEAA 381
+EE E++ EAA
Sbjct: 773 QEEQEKKAKEAA 784
Score = 63.2 bits (152), Expect = 6e-10
Identities = 84/360 (23%), Positives = 148/360 (41%), Gaps = 49/360 (13%)
Query: 89 AFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET-----TEK 143
++LERL E QK E E +E +P + A +P N N+T T
Sbjct: 357 SYLERLLNVEVP-QKVGSEQKEPPEEAEP-VAAAEPEVPENNGNNSWPHNDTEIANSTPN 414
Query: 144 EEKSESRQERYEIEETETVT-----------KSYQKNDWRDAEENKKEDKEKEEEEEEKP 192
+ + S E + E T + +K ++ A E++ E+EE + P
Sbjct: 415 PKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPP 474
Query: 193 KRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE-PKEEVKSF----- 246
+ K K+ TF +++ + P+ +KSF
Sbjct: 475 R----------SKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNT 524
Query: 247 ---MDRKKGFTEVKSQNGEFMTHK-----LKHTENTFSRPGGRASVDTKEAEGAPQV-EA 297
MD K F E + Q E + K L+ + + V K E +V +A
Sbjct: 525 PLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 584
Query: 298 GKRLEELRRRRGETESEEFEKLKQKQQEAALE-LEELKKKREERRKVLEEEEQRRKQEEA 356
+R+E+++ + + ++F ++ +K ++A E L E K K++ K +EE E RRKQEE
Sbjct: 585 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644
Query: 357 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAE 416
R+LR ++ EE ERR E +K+++ ++ L + + + + +ER E
Sbjct: 645 ARRLRWLQQ-----EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/214 (22%), Positives = 105/214 (49%), Gaps = 22/214 (10%)
Query: 32 ARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFL 91
ARER + ++E+ +KQ E+ Q+ ++ E + + +E+AK ++E +
Sbjct: 584 ARERVEQMKEEK--KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 641
Query: 92 ERLARR-----EERRQKRLQEALERQKEFDPTITD--ASLSLPSRRMQNDTAENETTEKE 144
E ARR +E ++R QE L+++KE + A + + + + E E E+E
Sbjct: 642 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 701
Query: 145 EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEE 204
+ + R+E+ E+ + AE+ ++ ++E+ + E E +R Q E+
Sbjct: 702 RREQERREQERREQERQL-----------AEQERRREQERLQAERELQEREKALRLQKEQ 750
Query: 205 KGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE 238
+++ K++K E++ + ++++E+ KK KE
Sbjct: 751 LQRELEEKKKK--EEQQRLAERQLQEEQEKKAKE 782
Score = 50.4 bits (119), Expect = 4e-06
Identities = 82/368 (22%), Positives = 137/368 (37%), Gaps = 54/368 (14%)
Query: 128 SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEE 187
SRR+ TAE S ER E S QK +AE E E
Sbjct: 336 SRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAA----EPE 391
Query: 188 EEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM 247
E S N E + K + P+ ++E K ++ +EP + +
Sbjct: 392 VPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKR 451
Query: 248 DRKKGFTEV----------------KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG 291
K+ +E+ K+ + K+ TF R +
Sbjct: 452 SYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQM-LMTPTS 510
Query: 292 APQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE---RRKVLEEEE 348
AP+ ++ R + + EK +Q+ LE L++K E RR+ +EE++
Sbjct: 511 APRSVMKSFIKRNTPLRMDPKCSFVEKERQR-------LENLRRKEEAEQLRRQKVEEDK 563
Query: 349 QRRKQEEADRKLREEEEKRRL--------------KEEIERRRAEAAEKRQKMPEDGLSD 394
+RR +E KL+ EE R++ K++IE++ A+ EK +K E+ L++
Sbjct: 564 RRRLEEV---KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE 620
Query: 395 DKKPFKCFTPKGSSL----KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSA 450
+K K K + K EE A L Q+ + HQ + K + E+ A
Sbjct: 621 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE--ERRHQELLQKKKEEEQERLRKA 678
Query: 451 IEGTKSAK 458
E + A+
Sbjct: 679 AEAKRLAE 686
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/137 (21%), Positives = 62/137 (45%), Gaps = 11/137 (8%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
Q ++ + ++++ QERLR+ E + L + +Q + ++E + Q
Sbjct: 653 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQ 710
Query: 82 VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
+ E E+ RRE+ R + +E ER+K +L L ++Q + E +
Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREK---------ALRLQKEQLQRELEEKKKK 761
Query: 142 EKEEKSESRQERYEIEE 158
E++++ RQ + E E+
Sbjct: 762 EEQQRLAERQLQEEQEK 778
Score = 38.9 bits (89), Expect = 0.013
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 10/131 (7%)
Query: 11 RSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEE----SLGQVTDQVEVNAQN 66
R A ++A QR + E+ RE+ RR ++ R ++++E+E + +Q + A+
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735
Query: 67 SVPDEEAKTTTTNTQVEGDDE----AAFLERLARR--EERRQKRLQEALERQKEFDPTIT 120
+ + E Q++ + E +RLA R +E ++K+ +EA K + T+
Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVD 795
Query: 121 DASLSLPSRRM 131
S + S +M
Sbjct: 796 VQSPACTSYQM 806
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 81.6 bits (200), Expect = 2e-15
Identities = 91/388 (23%), Positives = 160/388 (41%), Gaps = 40/388 (10%)
Query: 6 GSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQ 65
GS G R S + D E + R ER + Q +S +
Sbjct: 574 GSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRD 633
Query: 66 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEAL-ERQKEFDPTITDASL 124
N D+ + + Q D+ LER RREERR R+ + ER +E D
Sbjct: 634 NRERDQRPSSPIRH-QGRNDE----LERDERREERRVDRVDDRRDERARERD-------- 680
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 184
R + E E + E+ R++ E+E + ++ RD E ++ D ++
Sbjct: 681 -----RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735
Query: 185 EEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 244
E E E + R E + EE+ + + +RE+ +E +E ++ ++DKE +E +
Sbjct: 736 ERERERERDREKEREREREERERERERERERERE------RERERERARERDKE-RERQR 788
Query: 245 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL 304
+ D+ KG + + + E ++ N R S EG+P R
Sbjct: 789 DWEDKDKGRDDRREKREE-----IREDRNPRDGHDERKSKKRYRNEGSP----SPRQSPK 839
Query: 305 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERR---KVLEEEEQRRKQEEADRKLR 361
RRR +S+ + K ++ L L ++ + +E R L E+ Q R +EE DRK
Sbjct: 840 RRREHSPDSDAYNSGDDKNEKHRL-LSQVVRPQESRSLSPSHLTEDRQGRWKEE-DRKPE 897
Query: 362 EEEEKRRLKEEIERRRAEAAEKRQKMPE 389
+E RR +E+ + + + +K+++ E
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQREQTE 925
Score = 70.1 bits (170), Expect = 5e-12
Identities = 87/410 (21%), Positives = 169/410 (41%), Gaps = 37/410 (9%)
Query: 23 RNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 82
R DD +E ARER R ++R R+++ E + ++ + + E + +
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 83 EGDDEAAFLERLARREERRQK---RLQEALERQKEFDPTITDASLSLPSRRMQNDTAENE 139
D ER RE R+K R +E ER++E + R + D
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERER 786
Query: 140 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDK-EKEEEEEEKPKR---- 194
+ E+K + R +R E + E + + D D ++KK + E + PKR
Sbjct: 787 QRDWEDKDKGRDDRRE--KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREH 844
Query: 195 --GSIGENQGEEKGTK-------VQAKREK------LQEDKP-TFKKEEIKDEKIK---- 234
S N G++K K V+ + + L ED+ +K+E+ K E+ +
Sbjct: 845 SPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR 904
Query: 235 -KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAP 293
+++E KE+V S +D+++ TE+ + + H ++ RA + K+
Sbjct: 905 YEEQELKEKVSS-VDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQ 963
Query: 294 QVEAGKRLEE---LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQR 350
+ K+ E+ + R ET SE+ + K+ + +E+ +KK + + +EE +
Sbjct: 964 KKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQ 1023
Query: 351 RKQEEADRKLREEEEKRRLKEEIERRRA--EAAEKRQKMPEDGLSDDKKP 398
+ +++ + K L E + E ++K++ SD+ P
Sbjct: 1024 QSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVP 1073
Score = 62.8 bits (151), Expect = 8e-10
Identities = 76/400 (19%), Positives = 162/400 (40%), Gaps = 33/400 (8%)
Query: 25 DDDEEEAARERR--RRARQER-LRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
DD E R+RR R R R LR ++ ++ D ++ P + T +
Sbjct: 448 DDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDY 507
Query: 82 VEGDDEAAFLERLARREERR---QKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE- 137
+ + + EE R + L+E R + + + ++ + + RM
Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRV 567
Query: 138 NETTEKEEKS------ESRQERYEIEETETVTKSYQKNDWRDAEENKKE--DKEKEEEEE 189
E EK + +S ++ SY + D +N+ + D E
Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHG 627
Query: 190 EKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI--KKDKEPKEEVKSFM 247
E+ +R + +Q + Q + ++L+ D+ ++EE + +++ ++D+ +E +
Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELERDE---RREERRVDRVDDRRDERARERDR--- 681
Query: 248 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR 307
+R++ + + E + K E R R KE + + E R R
Sbjct: 682 ERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERER 741
Query: 308 RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKR 367
+ E E + +++++E E E +++ ER + E +++R +Q + + K + +++R
Sbjct: 742 ERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRR 801
Query: 368 RLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGS 407
+EEI + + P DG D++K K + +GS
Sbjct: 802 EKREEI---------REDRNPRDG-HDERKSKKRYRNEGS 831
Score = 49.7 bits (117), Expect = 7e-06
Identities = 79/416 (18%), Positives = 165/416 (39%), Gaps = 57/416 (13%)
Query: 4 GSGSHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVN 63
G S+ RRS + +R + ++ E ++R +E ++E S G+ ++ ++
Sbjct: 69 GYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIK 128
Query: 64 -AQNSVPDEEAKTTTTNTQVEGDDEAAF---------LERLARREERRQKRL-QEALERQ 112
+ P+ E + T + D LE ++ +R +L QE +E++
Sbjct: 129 ITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKR 188
Query: 113 ------KEFDPTITDASLS-LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKS 165
KE P + + LS PS R + + + +++ K S S+++R +T V+
Sbjct: 189 EEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSS-SASKKDR----KTSAVSSP 243
Query: 166 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQED----KP 221
D + N K NQ ++KG + + + ED K
Sbjct: 244 LL-----DQQRNSKT-------------------NQSKKKGPRTPSPPPPIPEDIALGKK 279
Query: 222 TFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHK----LKHTENTFSR 277
+K ++KD +K ++ K+ + F +++ + +S + H H+ ++ S
Sbjct: 280 YKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSG 339
Query: 278 PGGRASVDTKEAEGAPQVEAGKRLEE-LRRRRGETESEEFEKLKQKQQEAALELEELKKK 336
+ + + P + L LRR S ++KQ +K
Sbjct: 340 SSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKG 399
Query: 337 REERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR-QKMPEDG 391
R + + + ++R ++ E R R+ E+ R + E E+ ++ + + R + P DG
Sbjct: 400 RHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG 455
Score = 39.7 bits (91), Expect = 0.007
Identities = 50/269 (18%), Positives = 116/269 (43%), Gaps = 32/269 (11%)
Query: 7 SHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN 66
SH L + S + R+ DD+ R+R R +++ +SL ++T + +
Sbjct: 1200 SHTSGRLRSPSNDSAHRSGDDQSG-----RKRVLHSGSRDREKTKSL-EITGERKSRIDQ 1253
Query: 67 SVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSL 126
E +++T+++ Q D + R + E RQ R FD
Sbjct: 1254 LKRGEPSRSTSSDRQ----DSRSHSSRRSSPESDRQVH-----SRSGSFDSR-------- 1296
Query: 127 PSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE- 185
R + D E++ + E+ ++RQ ++ + + ++ ++ R+ E ++ DK ++
Sbjct: 1297 -DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDL 1355
Query: 186 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE-KIKKDKEPKEEVK 244
+ E E+ S+ ++ ++ ++ + + + K+ E K E + ++D E
Sbjct: 1356 DRERERLISDSVERDRDRDRDRTFESSQIE------SVKRCEAKLEGEHERDLESTSRDS 1409
Query: 245 SFMDRKKGFTEVKSQNGEFMTHKLKHTEN 273
+D+++ ++ S G T+K + TE+
Sbjct: 1410 LALDKERMDKDLGSVQGFEETNKSERTES 1438
Score = 35.4 bits (80), Expect = 0.14
Identities = 41/207 (19%), Positives = 80/207 (38%), Gaps = 16/207 (7%)
Query: 332 ELKKKREERRKVLEEEEQRRKQEEADRKLREEEE--KRRLKEEIERRRAEAAEKRQKMPE 389
+L+++ + +R+ ++ E Q+R EE+ +R+E + R KE+I+ + E ++ E
Sbjct: 84 DLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVE 143
Query: 390 -DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYT 448
+ DD L +E + + + + + K + I+ K + E
Sbjct: 144 WETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVR 203
Query: 449 SAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVS 508
S + + S + + + P + K K + SSP N +T
Sbjct: 204 SKLSPSPSLRKSSKSPKRKSSPKSSSASKKD--RKTSAVSSPLLDQQRNSKT-------- 253
Query: 509 SRINEWLTKTPDGNKSPAPKPSDLRPG 535
N+ K P P P P D+ G
Sbjct: 254 ---NQSKKKGPRTPSPPPPIPEDIALG 277
Score = 32.3 bits (72), Expect = 1.2
Identities = 54/306 (17%), Positives = 117/306 (38%), Gaps = 50/306 (16%)
Query: 118 TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN 177
+ + +++++ + +T N ++ + + R E ET VT DA+
Sbjct: 1129 SFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIE-------DAQHR 1181
Query: 178 KKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 237
K D+++ S+G N+ T + + + + + +
Sbjct: 1182 KPMDQKRSS---------SLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGS 1232
Query: 238 EPKEEVKSFM---DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 294
+E+ KS +RK ++K GE P S D +++
Sbjct: 1233 RDREKTKSLEITGERKSRIDQLK--RGE---------------PSRSTSSDRQDSRS--- 1272
Query: 295 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 354
+ +R R+ + S F+ + Q+ E + ++RE R+ + QR
Sbjct: 1273 -HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHD---RERERERR---DTRQREWDR 1325
Query: 355 EADRKLREEEEKRRLKE-EIER---RRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLK 410
+AD+ ++ RL+E E ER +R + +R+++ D + D+ + T + S ++
Sbjct: 1326 DADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIE 1385
Query: 411 IEERAE 416
+R E
Sbjct: 1386 SVKRCE 1391
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 80.9 bits (198), Expect = 3e-15
Identities = 87/316 (27%), Positives = 157/316 (49%), Gaps = 31/316 (9%)
Query: 94 LARRE--ERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE------ 145
LARR+ E R++RL E+L Q+E + + R+ + + E E+E+
Sbjct: 569 LARRQTIEERKERL-ESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQE 627
Query: 146 ----KSESRQERYE-IEETETVTKSYQKNDWRDAEENKKE---DKEKEEEEEEKPKRGSI 197
K ++ +ER E I++TE K+++ D D EE + K+ E+ E+EK +
Sbjct: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQER 687
Query: 198 GENQGEEKGTKVQAKR-EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
+NQ ++ +AKR E++ K ++++ IKD + + +E + ++R+K
Sbjct: 688 LKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKAL--- 744
Query: 257 KSQNGEFMTHKLKHTENTFSR-PGGRASV---DTKEAEGAPQVEAGKRLEELRRRRGETE 312
++ M+ L+ + R R SV K+ E E RLEE +R+R E
Sbjct: 745 --EHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEER 802
Query: 313 SEEFEKLKQKQQEAALELEELKKKREERRKV--LEEEEQRRKQEEADRKLREEEEKRRLK 370
+ + K+++++ E E++ K+REER + + EE+ R+ +E +KL E E K+R +
Sbjct: 803 RITYYREKEEEEQRRAE-EQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQR 861
Query: 371 E-EIERRRAEAAEKRQ 385
E EIE R E+R+
Sbjct: 862 ELEIEERERRREEERR 877
Score = 77.4 bits (189), Expect = 3e-14
Identities = 81/309 (26%), Positives = 144/309 (46%), Gaps = 36/309 (11%)
Query: 109 LERQKEFDPTITDASLSLPSRRMQNDTAENETTE-KEEKSES---RQERYEIEETETVTK 164
L+ ++E A L + Q A +T E ++E+ ES ++E+ E+E+ E +
Sbjct: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQ 602
Query: 165 SYQK-NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKR------EKLQ 217
+K + R +E K+ +KE+ +E E+ K+ ++ E + K T++ AK E L+
Sbjct: 603 KVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
Query: 218 EDKPTFKKEEIKDEKIKKDKEPKEEVKS------FMDRKKGFTEVKSQNGEFMTHKLKHT 271
E P F + ++ K+ KE +E +K+ + +R K E+ + ++K
Sbjct: 663 ELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDM 722
Query: 272 ENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE 331
+ + R + Q+E K LE R E + ++ K ++ E
Sbjct: 723 DLWEQQEEERITT--------MQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEE 774
Query: 332 ELK----KKREERRKVLEEEEQRRKQEEADRKLRE--EEEKRR-----LKEEIERRRAEA 380
+LK + EER LEE +++RK+E RE EEE+RR LKE ER RAE
Sbjct: 775 KLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
Query: 381 AEKRQKMPE 389
A++ +++ E
Sbjct: 835 AKREEELRE 843
Score = 75.5 bits (184), Expect = 1e-13
Identities = 88/416 (21%), Positives = 178/416 (42%), Gaps = 70/416 (16%)
Query: 19 IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPD--EEAKTT 76
I ++ + ++ EA ++ R+A +ERLRQ+ +E ++ + E + +V + E+ K T
Sbjct: 587 IQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKT 646
Query: 77 TTNTQVEGDDEAAFLERL------ARREERRQKRLQEALERQKEFDPTITDASLSLPSRR 130
+ D + LE L A++ E+ +K +E ER K
Sbjct: 647 ELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKN---------------- 690
Query: 131 MQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE--ENKKEDK------ 182
+E+K + + +EE + +Y++ +D + E ++E++
Sbjct: 691 ------------QEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738
Query: 183 EKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE 242
E+E+ E K + + E++ + +++A R+ + E+K +E + +E+ + +E K +
Sbjct: 739 EREKALEHKNRMSRMLEDR-DLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQ 797
Query: 243 VKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE 302
K +R+ + K + + + E RA +E E E K+LE
Sbjct: 798 RKE--ERRITYYREKEEEEQRRAEEQMLKEREERERAERAK---REEELREYQERVKKLE 852
Query: 303 ELRRRRGETESEEFEKLKQKQQEAALELEELKKK--------------------REERRK 342
E+ R++ + E E E+ +++++E L L +K E RR
Sbjct: 853 EVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRG 912
Query: 343 VLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKP 398
E+E +R + + DR R +EE+ R + E R ++P G+ DD+ P
Sbjct: 913 PPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGP 968
Score = 53.5 bits (127), Expect = 5e-07
Identities = 54/238 (22%), Positives = 108/238 (45%), Gaps = 31/238 (13%)
Query: 13 LAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV---NAQNSVP 69
L A Q Y+ EE E R +ER RQ++EE + ++ E A+ +
Sbjct: 764 LKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQML 823
Query: 70 DEEAKTTTTNTQVEGDDEAAFLERLARREE----RRQKRLQ-EALERQKEFDPTITDASL 124
E + ++ + ER+ + EE +RQ+ L+ E ER++E + + D+SL
Sbjct: 824 KEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSL 883
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 184
S R + +E T K +++S R E K +++ + RD + + + D+E+
Sbjct: 884 SRKDSRWGDRDSEG-TWRKGPEADSEWRRGPPE------KEWRRGEGRDEDRSHRRDEER 936
Query: 185 -----EEEEEEK---------PKRGSIGENQGEEKGTKV-QAKREKLQEDKPTFKKEE 227
++E+ E P+RG + +++G +G + + R +D+P+++ +
Sbjct: 937 PRRLGDDEDREPSLRPDDDRVPRRG-MDDDRGPRRGPEEDRFSRRGADDDRPSWRNTD 993
Score = 38.5 bits (88), Expect = 0.016
Identities = 50/261 (19%), Positives = 107/261 (40%), Gaps = 32/261 (12%)
Query: 168 KNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEE 227
+ WR+ ++++ + +++ P+RG K REK E+
Sbjct: 1137 RGPWRNMDDDRLS---RRADDDRFPRRGDDSRPGPWRPLVKPGGWREK----------EK 1183
Query: 228 IKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTK 287
++E +E + + DR+K + ++ + K E R VD +
Sbjct: 1184 AREESWGPPRESRPSEEREWDREKE----RDRDNQDREENDKDPERERDR---ERDVDRE 1236
Query: 288 EAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE 347
+ P+ E G R RG +EE + + + ++ +++R++RR + E
Sbjct: 1237 DRFRRPRDEGGWR-------RGP--AEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERR 1287
Query: 348 EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKR---QKMPEDGLSDDKKPFKCFTP 404
+ R ++ LR E E+ + R+ + E+R +++P LS D++ +
Sbjct: 1288 DLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRER 1347
Query: 405 KGSSLKIEERAEFLNKSVQKS 425
+G K RAE +S++++
Sbjct: 1348 EGEKEKASWRAEKDRESLRRT 1368
Score = 36.6 bits (83), Expect = 0.062
Identities = 43/211 (20%), Positives = 90/211 (42%), Gaps = 37/211 (17%)
Query: 92 ERLARREER----RQKRLQEALE--RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 145
E+ REE R+ R E E R+KE D D R +ND + E E
Sbjct: 1180 EKEKAREESWGPPRESRPSEEREWDREKERDRDNQD--------REENDK-DPERERDRE 1230
Query: 146 KSESRQERYEIEETETVTK---SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQG 202
+ R++R+ E + + + + WRD+ ++D+++++ E+ R + E +
Sbjct: 1231 RDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSR--RDDRDRDDRRRERDDRRDLRERRD 1288
Query: 203 -----EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR-------- 249
+ +G ++++RE++ + + ++ KD+++++ P+ + R
Sbjct: 1289 LRDDRDRRGPPLRSEREEVSSWR---RADDRKDDRVEERDPPRRVPPPALSRDRERDRDR 1345
Query: 250 -KKGFTEVKSQNGEFMTHKLKHTENTFSRPG 279
++G E S E L+ T+N G
Sbjct: 1346 EREGEKEKASWRAEKDRESLRRTKNETDEDG 1376
Score = 33.9 bits (76), Expect = 0.40
Identities = 38/203 (18%), Positives = 79/203 (38%), Gaps = 8/203 (3%)
Query: 137 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 196
E E +E R+ R EE E + + D +D EEN K D E+E + E R
Sbjct: 1180 EKEKAREESWGPPRESRPS-EEREWDREKERDRDNQDREENDK-DPERERDRERDVDRED 1237
Query: 197 IGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
+E G R E+ +++ +D++ + D+ + + + + ++ +
Sbjct: 1238 RFRRPRDEGGW-----RRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDD 1292
Query: 257 KSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316
+ + G + + + +++ R R +E + +V + R R E
Sbjct: 1293 RDRRGPPLRSE-REEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEK 1351
Query: 317 EKLKQKQQEAALELEELKKKREE 339
EK + ++ L K + +E
Sbjct: 1352 EKASWRAEKDRESLRRTKNETDE 1374
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 80.9 bits (198), Expect = 3e-15
Identities = 100/442 (22%), Positives = 191/442 (43%), Gaps = 55/442 (12%)
Query: 10 RRSLAA---LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN 66
RR+L++ +I + D EE++ + +++ ++ ++K V ++ + +
Sbjct: 1099 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVI-----VKEKKRNSLRT 1153
Query: 67 SVPDEEAK-TTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 125
S ++A T+++++ +E DD+ + E + ++ + L F + D +LS
Sbjct: 1154 STKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALS 1213
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
+D +++ + E + + EI+ + + +D + EE KK ++
Sbjct: 1214 KSVPVTVDD--DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD--EPEEGKKRTGKQN 1269
Query: 186 EEE--EEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 243
EE +E+ K E+ + + +K R +L K T E +EK K KE KE V
Sbjct: 1270 EENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE-V 1328
Query: 244 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 303
K RK V S++ E ++ F G V E E P+ + K+ E
Sbjct: 1329 KGRNRRK-----VSSEDSE---------DSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1374
Query: 304 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE-------- 355
+R + ++ ++K ++ ++ +++ EE+ + EEEE+ ++EE
Sbjct: 1375 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1434
Query: 356 ------------ADRKLREEEEKRRLKEEIERRR--AEAAEKRQKMPEDGLSDDKKPFKC 401
D KLR E + LKEE ERR+ AE +R+K+ E +D P KC
Sbjct: 1435 PGKGRKKIRKILKDDKLRTETQ-NALKEEEERRKRIAEREREREKLREVIEIEDASPTKC 1493
Query: 402 FTPKGSSLKIEERAEFLNKSVQ 423
P + L ++E E VQ
Sbjct: 1494 --PITTKLVLDEDEETKEPLVQ 1513
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/375 (20%), Positives = 149/375 (39%), Gaps = 70/375 (18%)
Query: 7 SHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN 66
S G +L+ + +DDD + + R+ +K E + E + +
Sbjct: 1206 SSGDEALSKSVPVTVDDDDDDNDP----------ENRIAKKMLLEEIKANLSSDEDGSSD 1255
Query: 67 SVPDEEAKTT-TTNTQVEGDDEA---AFLERLARREERRQKRLQEALERQKEFDPTITDA 122
P+E K T N + GD+EA E + EE ++ R + L R K T++D
Sbjct: 1256 DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL---TVSDG 1312
Query: 123 SLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDK 182
E +T KE K + R ++ ++ +Q++ E E +
Sbjct: 1313 ESG----------EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG---VSEEVSESE 1359
Query: 183 EKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE 242
+++ K+ + ENQ K K + +R K+QED + K ++E+ +K++E +EE
Sbjct: 1360 DEQRPRTRSAKKAELEENQRSYKQKK-KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Query: 243 VKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE 302
+ + + EN S+ G+ G ++ + +
Sbjct: 1419 EEE--------------------EEEEEDENDDSKSPGK---------GRKKIRKILKDD 1449
Query: 303 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK--L 360
+LR EE E+ K+ + E +++RE+ R+V+E E+ + K L
Sbjct: 1450 KLRTETQNALKEEEERRKR--------IAEREREREKLREVIEIEDASPTKCPITTKLVL 1501
Query: 361 REEEEKRRLKEEIER 375
E+EE + ++ R
Sbjct: 1502 DEDEETKEPLVQVHR 1516
Score = 55.5 bits (132), Expect = 1e-07
Identities = 84/411 (20%), Positives = 175/411 (42%), Gaps = 64/411 (15%)
Query: 40 RQERLRQKQEEESLGQVTDQVEVNA---QNSVPDEEAKTTTTNTQVEGDDEAAFLERLAR 96
+ +L + ++ E++ Q +D E+ A + S + + T ++ + + + +
Sbjct: 674 KPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQA 733
Query: 97 REERRQKRLQEALERQKEFDP----TITDASLSLPSRRMQNDTAENETT-EKEEKSESRQ 151
++ + KR +++ +FD + + +S R+ Q++++ ++ EKE KS S+
Sbjct: 734 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSK- 792
Query: 152 ERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQA 211
I T K D+ E++K K+ + + K + S ++G+ A
Sbjct: 793 ----IGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTS-------QEGSSDDA 841
Query: 212 KREKLQEDKPTFKKEEIKDEKIK--KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 269
+R++ +E + + KD I +D+ PK++ S S +G KL
Sbjct: 842 ERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQAS-----------ASTDG---VDKLS 887
Query: 270 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE---------LRRRRGETESEEFEKLK 320
E +F+ R +TKE + + K++++ L++ + + SE+ +K
Sbjct: 888 GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 947
Query: 321 QKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEA 380
+K E E KK + ++KV++ E+Q + KL E EE + I
Sbjct: 948 KKGTE------EKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI------- 994
Query: 381 AEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 431
K ++G +D +K K K +S K +E +++ KS K S+
Sbjct: 995 -----KQIKNGTTDGEKKSKKIRDK-TSKKKDELSDYAEKSTGKGDSCDSS 1039
Score = 43.1 bits (100), Expect = 7e-04
Identities = 79/405 (19%), Positives = 153/405 (37%), Gaps = 95/405 (23%)
Query: 65 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 124
++ + D K+T + ++ RE++R K L ++ +++ D S
Sbjct: 1019 KDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ-------DCSS 1071
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 184
S + + N + ++ ++ E R ER + + + DAEE+ +++K+K
Sbjct: 1072 SDTEKYSMKEDGCNSSDKRLKRIELR-ERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKK 1130
Query: 185 EEEEEEKPK-----------------------------------RGSIGENQGEEKGTKV 209
++ K K + SIGE +E+ K+
Sbjct: 1131 KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ--KI 1188
Query: 210 QAKREKLQEDKPTFKKEEIKDEKIKK-----------DKEPK---------EEVKSFMDR 249
+ E L T + DE + K D +P+ EE+K+ +
Sbjct: 1189 KPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSS 1248
Query: 250 -KKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGK------RLE 302
+ G ++ + + G+ T K ++ EN PG + + +E E K RL
Sbjct: 1249 DEDGSSDDEPEEGKKRTGK-QNEEN----PGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303
Query: 303 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE-----------RRKVLEEEEQRR 351
+ + ES E +K K K+ + K E+ +V E E+++R
Sbjct: 1304 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1363
Query: 352 KQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 396
+ + +K EE +R K++ +RRR K+ ED S++K
Sbjct: 1364 PRTRSAKKAELEENQRSYKQKKKRRRI-------KVQEDSSSENK 1401
Score = 34.7 bits (78), Expect = 0.24
Identities = 73/387 (18%), Positives = 147/387 (37%), Gaps = 45/387 (11%)
Query: 47 KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 106
K+ ++ L + ++ Q+ E+ K + E + F +++ + E++ +
Sbjct: 917 KKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSD 976
Query: 107 --EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 164
E L ++E ++++N T + E K+ + ++ +++ E+ ++ K
Sbjct: 977 GTEKLPEREEI------CHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL--SDYAEK 1028
Query: 165 SYQKNDWRDAEENKKEDKEKEEEEEEK--------PKRGSIGENQGEEKGTK-------- 208
S K D D+ E+KK E+++ KR + E+ K
Sbjct: 1029 STGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSD 1088
Query: 209 VQAKREKLQEDKPTFKKEEIK---------DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 259
+ KR +L+E + K K D + + K++ ++ +K + K +
Sbjct: 1089 KRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1148
Query: 260 NGEFMTHKLKHTENTFSRPGGRASVDTKE-AEGAPQVEAGKRLEE---LRRRRGETESEE 315
N + K K + T S D EG+ + K + E L G +S
Sbjct: 1149 NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSG 1208
Query: 316 FEKLKQKQQEAALELEELKKKREER--RKVLEEEEQRRKQEEADRKLREEEE---KRRLK 370
E L K ++ ++ E R +K+L EE + + D +E E KR K
Sbjct: 1209 DEAL-SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK 1267
Query: 371 EEIERRRAEAAEKRQKMPEDGLSDDKK 397
+ E E A+ + D S++ K
Sbjct: 1268 QNEENPGDEEAKNQVNSESDSDSEESK 1294
Score = 33.5 bits (75), Expect = 0.53
Identities = 75/368 (20%), Positives = 142/368 (38%), Gaps = 46/368 (12%)
Query: 53 LGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQK-RLQEALER 111
L Q TD E+++ + +A + V D + A LA E+ + R +A+ +
Sbjct: 336 LKQATDNSEISSATKLRQLKAFKS-----VLADIKKA---HLALEEDLNSEFRAMDAVNK 387
Query: 112 QKEF-DPTITDASLSLPSRRMQNDTA-ENETTEKEEKSESRQERYEIEETETVTKSYQKN 169
+K + + DA +R+ + A E + K E SR++ + V Q+
Sbjct: 388 EKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRT 447
Query: 170 DWRDAEENKKEDKEKEEEEEEKPKR-----------GSIGENQGEEKGTKVQAKRE-KLQ 217
+ E+KK D+++E + E S+ E+ E T ++ + Q
Sbjct: 448 NKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQ 507
Query: 218 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL--KHTENTF 275
D + ++E++ +K + K D + G +KS+ +T +L K T +
Sbjct: 508 GDGSSGTEQEVESSSVKLNISSK-------DNRGG---IKSKTTAKVTKELYVKLTPVSL 557
Query: 276 SR---PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEE 332
S G ++ +G +LE+ + +++E + E +L LEE
Sbjct: 558 SNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHL-----VENEVSLLLEE 612
Query: 333 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 392
+R R K RR E +EE +E ++ +K ++ D
Sbjct: 613 SDLRRSPRVKT---TPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSA 669
Query: 393 SDDKKPFK 400
D+ KP K
Sbjct: 670 IDNPKPNK 677
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 80.9 bits (198), Expect = 3e-15
Identities = 100/442 (22%), Positives = 191/442 (43%), Gaps = 55/442 (12%)
Query: 10 RRSLAA---LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN 66
RR+L++ +I + D EE++ + +++ ++ ++K V ++ + +
Sbjct: 1137 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVI-----VKEKKRNSLRT 1191
Query: 67 SVPDEEAK-TTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 125
S ++A T+++++ +E DD+ + E + ++ + L F + D +LS
Sbjct: 1192 STKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALS 1251
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
+D +++ + E + + EI+ + + +D + EE KK ++
Sbjct: 1252 KSVPVTVDD--DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD--EPEEGKKRTGKQN 1307
Query: 186 EEE--EEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 243
EE +E+ K E+ + + +K R +L K T E +EK K KE KE V
Sbjct: 1308 EENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE-V 1366
Query: 244 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 303
K RK V S++ E ++ F G V E E P+ + K+ E
Sbjct: 1367 KGRNRRK-----VSSEDSE---------DSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1412
Query: 304 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE-------- 355
+R + ++ ++K ++ ++ +++ EE+ + EEEE+ ++EE
Sbjct: 1413 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1472
Query: 356 ------------ADRKLREEEEKRRLKEEIERRR--AEAAEKRQKMPEDGLSDDKKPFKC 401
D KLR E + LKEE ERR+ AE +R+K+ E +D P KC
Sbjct: 1473 PGKGRKKIRKILKDDKLRTETQ-NALKEEEERRKRIAEREREREKLREVIEIEDASPTKC 1531
Query: 402 FTPKGSSLKIEERAEFLNKSVQ 423
P + L ++E E VQ
Sbjct: 1532 --PITTKLVLDEDEETKEPLVQ 1551
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/375 (20%), Positives = 149/375 (39%), Gaps = 70/375 (18%)
Query: 7 SHGRRSLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN 66
S G +L+ + +DDD + + R+ +K E + E + +
Sbjct: 1244 SSGDEALSKSVPVTVDDDDDDNDP----------ENRIAKKMLLEEIKANLSSDEDGSSD 1293
Query: 67 SVPDEEAKTT-TTNTQVEGDDEA---AFLERLARREERRQKRLQEALERQKEFDPTITDA 122
P+E K T N + GD+EA E + EE ++ R + L R K T++D
Sbjct: 1294 DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL---TVSDG 1350
Query: 123 SLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDK 182
E +T KE K + R ++ ++ +Q++ E E +
Sbjct: 1351 ESG----------EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG---VSEEVSESE 1397
Query: 183 EKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE 242
+++ K+ + ENQ K K + +R K+QED + K ++E+ +K++E +EE
Sbjct: 1398 DEQRPRTRSAKKAELEENQRSYKQKK-KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1456
Query: 243 VKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE 302
+ + + EN S+ G+ G ++ + +
Sbjct: 1457 EEE--------------------EEEEEDENDDSKSPGK---------GRKKIRKILKDD 1487
Query: 303 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK--L 360
+LR EE E+ K+ + E +++RE+ R+V+E E+ + K L
Sbjct: 1488 KLRTETQNALKEEEERRKR--------IAEREREREKLREVIEIEDASPTKCPITTKLVL 1539
Query: 361 REEEEKRRLKEEIER 375
E+EE + ++ R
Sbjct: 1540 DEDEETKEPLVQVHR 1554
Score = 55.5 bits (132), Expect = 1e-07
Identities = 84/411 (20%), Positives = 175/411 (42%), Gaps = 64/411 (15%)
Query: 40 RQERLRQKQEEESLGQVTDQVEVNA---QNSVPDEEAKTTTTNTQVEGDDEAAFLERLAR 96
+ +L + ++ E++ Q +D E+ A + S + + T ++ + + + +
Sbjct: 712 KPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQA 771
Query: 97 REERRQKRLQEALERQKEFDP----TITDASLSLPSRRMQNDTAENETT-EKEEKSESRQ 151
++ + KR +++ +FD + + +S R+ Q++++ ++ EKE KS S+
Sbjct: 772 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSK- 830
Query: 152 ERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQA 211
I T K D+ E++K K+ + + K + S ++G+ A
Sbjct: 831 ----IGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTS-------QEGSSDDA 879
Query: 212 KREKLQEDKPTFKKEEIKDEKIK--KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 269
+R++ +E + + KD I +D+ PK++ S S +G KL
Sbjct: 880 ERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQAS-----------ASTDG---VDKLS 925
Query: 270 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE---------LRRRRGETESEEFEKLK 320
E +F+ R +TKE + + K++++ L++ + + SE+ +K
Sbjct: 926 GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 985
Query: 321 QKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEA 380
+K E E KK + ++KV++ E+Q + KL E EE + I
Sbjct: 986 KKGTE------EKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI------- 1032
Query: 381 AEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 431
K ++G +D +K K K +S K +E +++ KS K S+
Sbjct: 1033 -----KQIKNGTTDGEKKSKKIRDK-TSKKKDELSDYAEKSTGKGDSCDSS 1077
Score = 43.1 bits (100), Expect = 7e-04
Identities = 79/405 (19%), Positives = 153/405 (37%), Gaps = 95/405 (23%)
Query: 65 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 124
++ + D K+T + ++ RE++R K L ++ +++ D S
Sbjct: 1057 KDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ-------DCSS 1109
Query: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 184
S + + N + ++ ++ E R ER + + + DAEE+ +++K+K
Sbjct: 1110 SDTEKYSMKEDGCNSSDKRLKRIELR-ERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKK 1168
Query: 185 EEEEEEKPK-----------------------------------RGSIGENQGEEKGTKV 209
++ K K + SIGE +E+ K+
Sbjct: 1169 KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ--KI 1226
Query: 210 QAKREKLQEDKPTFKKEEIKDEKIKK-----------DKEPK---------EEVKSFMDR 249
+ E L T + DE + K D +P+ EE+K+ +
Sbjct: 1227 KPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSS 1286
Query: 250 -KKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGK------RLE 302
+ G ++ + + G+ T K ++ EN PG + + +E E K RL
Sbjct: 1287 DEDGSSDDEPEEGKKRTGK-QNEEN----PGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1341
Query: 303 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE-----------RRKVLEEEEQRR 351
+ + ES E +K K K+ + K E+ +V E E+++R
Sbjct: 1342 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1401
Query: 352 KQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 396
+ + +K EE +R K++ +RRR K+ ED S++K
Sbjct: 1402 PRTRSAKKAELEENQRSYKQKKKRRRI-------KVQEDSSSENK 1439
Score = 35.0 bits (79), Expect = 0.18
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 14/112 (12%)
Query: 134 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE-ENKKEDKEKEEEEEEKP 192
+ ++ E T EKS+S + VTK + +D + + E ED E E +
Sbjct: 58 ENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDIT 117
Query: 193 KRGSIGENQGEEKGTKVQAKREKLQEDKPTFK------KEEIKDEKIKKDKE 238
Q KGT + L EDK FK + ++K E +KK E
Sbjct: 118 M-------QSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGE 162
Score = 34.7 bits (78), Expect = 0.24
Identities = 73/387 (18%), Positives = 147/387 (37%), Gaps = 45/387 (11%)
Query: 47 KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 106
K+ ++ L + ++ Q+ E+ K + E + F +++ + E++ +
Sbjct: 955 KKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSD 1014
Query: 107 --EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 164
E L ++E ++++N T + E K+ + ++ +++ E+ ++ K
Sbjct: 1015 GTEKLPEREEI------CHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL--SDYAEK 1066
Query: 165 SYQKNDWRDAEENKKEDKEKEEEEEEK--------PKRGSIGENQGEEKGTK-------- 208
S K D D+ E+KK E+++ KR + E+ K
Sbjct: 1067 STGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSD 1126
Query: 209 VQAKREKLQEDKPTFKKEEIK---------DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 259
+ KR +L+E + K K D + + K++ ++ +K + K +
Sbjct: 1127 KRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1186
Query: 260 NGEFMTHKLKHTENTFSRPGGRASVDTKE-AEGAPQVEAGKRLEE---LRRRRGETESEE 315
N + K K + T S D EG+ + K + E L G +S
Sbjct: 1187 NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSG 1246
Query: 316 FEKLKQKQQEAALELEELKKKREER--RKVLEEEEQRRKQEEADRKLREEEE---KRRLK 370
E L K ++ ++ E R +K+L EE + + D +E E KR K
Sbjct: 1247 DEAL-SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK 1305
Query: 371 EEIERRRAEAAEKRQKMPEDGLSDDKK 397
+ E E A+ + D S++ K
Sbjct: 1306 QNEENPGDEEAKNQVNSESDSDSEESK 1332
Score = 33.5 bits (75), Expect = 0.53
Identities = 75/368 (20%), Positives = 142/368 (38%), Gaps = 46/368 (12%)
Query: 53 LGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQK-RLQEALER 111
L Q TD E+++ + +A + V D + A LA E+ + R +A+ +
Sbjct: 374 LKQATDNSEISSATKLRQLKAFKS-----VLADIKKA---HLALEEDLNSEFRAMDAVNK 425
Query: 112 QKEF-DPTITDASLSLPSRRMQNDTA-ENETTEKEEKSESRQERYEIEETETVTKSYQKN 169
+K + + DA +R+ + A E + K E SR++ + V Q+
Sbjct: 426 EKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRT 485
Query: 170 DWRDAEENKKEDKEKEEEEEEKPKR-----------GSIGENQGEEKGTKVQAKRE-KLQ 217
+ E+KK D+++E + E S+ E+ E T ++ + Q
Sbjct: 486 NKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQ 545
Query: 218 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL--KHTENTF 275
D + ++E++ +K + K D + G +KS+ +T +L K T +
Sbjct: 546 GDGSSGTEQEVESSSVKLNISSK-------DNRGG---IKSKTTAKVTKELYVKLTPVSL 595
Query: 276 SR---PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEE 332
S G ++ +G +LE+ + +++E + E +L LEE
Sbjct: 596 SNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHL-----VENEVSLLLEE 650
Query: 333 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 392
+R R K RR E +EE +E ++ +K ++ D
Sbjct: 651 SDLRRSPRVKT---TPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSA 707
Query: 393 SDDKKPFK 400
D+ KP K
Sbjct: 708 IDNPKPNK 715
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 80.5 bits (197), Expect = 4e-15
Identities = 88/399 (22%), Positives = 178/399 (44%), Gaps = 38/399 (9%)
Query: 10 RRSLAALSQIAYQRND--DDEEEAARERRRRA--RQERLRQKQEEESLGQVTDQVEVNAQ 65
R+ + ++ + N D EE A+ER + R +LR +QEEE ++ +NA+
Sbjct: 145 RKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDM--SKIILNAK 202
Query: 66 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 125
+ Q E D E L+++ E ++ + QE LER++ +
Sbjct: 203 CHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREE--------R 254
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
+ RR + E E+ +E R++ E E+ + Q+ D +D E +++ + +
Sbjct: 255 IRGRRQIVEQMEKNQEERSLLAEQREQ--EKEQMLEYMEQLQEEDLKDMERRQQQKLKMQ 312
Query: 186 EE------EEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEK---IKKD 236
E E +K K + + + ++ K++ +E + ++E I+ EK I +
Sbjct: 313 AEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARL 372
Query: 237 KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVE 296
+ +E+ + + + ++Q + K EN R ++T+ ++E
Sbjct: 373 RAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENA------RKKMETEAELRKSRLE 426
Query: 297 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK---- 352
E + + + +EFE++ + Q+E +E E L+++++ ++ E RR+
Sbjct: 427 QVAFKEHALAVQVQRDRDEFERILRAQREQ-IEKERLEEEKKATGRLQHANELRRQVREN 485
Query: 353 -QEEADRKLREEEEKRRLKEEIERRRAEAAE-KRQKMPE 389
Q+E ++ EE RRLKEE ++RR E KR+K+ E
Sbjct: 486 QQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEE 524
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/212 (18%), Positives = 94/212 (44%), Gaps = 16/212 (7%)
Query: 222 TFKKEEIKDEKIKKDKEPKEEV----KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 277
T ++ E +D+ KK+KE + K M +K+ + + + +N R
Sbjct: 120 TREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQR 179
Query: 278 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEK---LKQKQQEAALELEELK 334
+E + ++ + +R + E ++ +K ++K+ + +E+E K
Sbjct: 180 ANKLRMEQEEELKDMSKIILNAKCHAIRDAQ-ILEKQQIQKELDTEEKRLDQMMEVERQK 238
Query: 335 --KKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 392
+++EE + EE R +++ ++ + +EE+ L E+ E+ + + E +++ E+ L
Sbjct: 239 SIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDL 298
Query: 393 SDDKKPFKCFTPKGSSLKIEERAEFLNKSVQK 424
D ++ + LK++ + +N QK
Sbjct: 299 KDMER------RQQQKLKMQAEIKRINDENQK 324
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 79.0 bits (193), Expect = 1e-14
Identities = 77/292 (26%), Positives = 134/292 (45%), Gaps = 29/292 (9%)
Query: 127 PSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 186
P+ + +D E E +++ S R EI+ +TV K +K + + EE K ED +KEE
Sbjct: 487 PAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKK--EEKKPEDIKKEE 544
Query: 187 EEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDK--PTFKKEEIKDEKIKKDKEPKEEVK 244
+++++ K G ++ + G++ + + + K P +K KE
Sbjct: 545 KDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVIS--------VKTTSRSKERSS 596
Query: 245 SFMDRKKGFTEVKSQNGEFMTHKLKHT-ENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 303
DRK +E K + K+K E R R +T+ Q E +RLE
Sbjct: 597 KSQDRK---SESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEA 653
Query: 304 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 363
R+ + + E+L+ + Q LE E ++++R ER ++ E E+R++QE R RE
Sbjct: 654 FHERKEKARLQR-ERLQLECQRQRLERERMERERLERERMRVERERRKEQE---RIHRER 709
Query: 364 EEKRRLKEEIERRRAEAAEKRQKMPED-GLSDDKKPFKCFTPKGSSLKIEER 414
EE RR +E++ R E + + P D DD + P+G + +E+R
Sbjct: 710 EELRRQQEQL---RYEQERRPGRRPYDLDRRDD-----AYWPEGKRVAMEDR 753
Score = 39.3 bits (90), Expect = 0.010
Identities = 36/163 (22%), Positives = 69/163 (42%), Gaps = 28/163 (17%)
Query: 33 RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE 92
R + + R+ ++K++ S ++ +Q E Q E +T E
Sbjct: 594 RSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRET----------------E 637
Query: 93 RLARREER-RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ 151
R RE+R R++RL+ ER+++ L +R++ + E E E+E R+
Sbjct: 638 RRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERE 697
Query: 152 ERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 194
R E Q+ R+ EE +++ ++ E+E +P R
Sbjct: 698 RRKE-----------QERIHREREELRRQQEQLRYEQERRPGR 729
Score = 39.3 bits (90), Expect = 0.010
Identities = 46/215 (21%), Positives = 90/215 (41%), Gaps = 27/215 (12%)
Query: 5 SGSHGRRSLAALSQIAYQRNDDD---------EEEAARERRRRARQERL---RQKQEEES 52
S S +R + + +I QR + E E RER +R R++RL +++E+
Sbjct: 603 SESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKAR 662
Query: 53 LGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQ 112
L + Q+E Q + + + E +ER R+E+ R R +E L RQ
Sbjct: 663 LQRERLQLECQRQRLERERMERERL-------ERERMRVERERRKEQERIHREREELRRQ 715
Query: 113 KEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWR 172
+E + P RR + ++ E K + ++RY + ++ +D+
Sbjct: 716 QE---QLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRY---RADFPRPDHRFHDFD 769
Query: 173 DAEENKKEDKEKEEEEEEKPKRGS--IGENQGEEK 205
+ + +D + E +P G G++ G+++
Sbjct: 770 HRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDR 804
Score = 34.7 bits (78), Expect = 0.24
Identities = 95/434 (21%), Positives = 160/434 (36%), Gaps = 74/434 (17%)
Query: 47 KQEEESLGQ--VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 104
K+E L Q D V + +EE + + + EGD + A E A + +
Sbjct: 230 KEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPE-EGDLDLAS-ESTAHAQSSKADS 287
Query: 105 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 164
L ++R+ P + + P + + A +++ E +E+ E E+ E T
Sbjct: 288 LLAVVKREPAEQPGDGERTDCEP---VGLEPAVEQSSAASELAEASSE--ELAEAPTEAP 342
Query: 165 SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK 224
S + D + E+ +K D + E PK S E + K +E+K
Sbjct: 343 SPEARDSK--EDGRKFDFDACNEVPPAPKESSTSEGADQ--------KMSSFKEEKDI-- 390
Query: 225 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG---GR 281
K IKDEK + V S R + + S T + +N FS+ G G
Sbjct: 391 KPIIKDEKGR--------VGSGSGRNLWVSGLSS------TTRATDLKNLFSKYGKVVGA 436
Query: 282 ASVDTKEAEGA---------PQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEE 332
V + GA EA K + L R E K K + A +L +
Sbjct: 437 KVVTNARSPGARCYGFVTMSTSDEATKCISHLHRT--ELHGRMISVEKAKNEPAGKKLSD 494
Query: 333 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 392
K+ ++ K+ + + + ++ + ++EEK KEE K PED
Sbjct: 495 RKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEE-------------KKPEDIK 541
Query: 393 SDDK-----KPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQY 447
++K KP P S + + + ++V KS + I K SR ++
Sbjct: 542 KEEKDQDELKP----GPTNRSRVTKSGSRGMERTVVMD---KSKGEPVISVKTTSRSKER 594
Query: 448 TSAIEGTKSAKPTK 461
+S + KS K
Sbjct: 595 SSKSQDRKSESKEK 608
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 77.8 bits (190), Expect = 2e-14
Identities = 104/477 (21%), Positives = 193/477 (40%), Gaps = 85/477 (17%)
Query: 29 EEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA 88
EE + + +++ + + E+ L QV D + Q + E+ K V+G
Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLVQVEDSL-AKKQEKLAQEKMKLALEKAMVQGKKRL 1950
Query: 89 AFLERLARREER---RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEK-- 143
+A+ E+ KRL E R E T++ SR+ + E E E+
Sbjct: 1951 RGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKL 2010
Query: 144 --EEKSESRQERYEIEETETVTKS----------YQKNDWRDAEENKKEDKEKEEEEEEK 191
EEK ++R E + K + + + A+ ++K K++E +E
Sbjct: 2011 SLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEP 2070
Query: 192 PKRGSIGE------------NQGEEKGTK------VQAKREKLQEDKPTFKKEEIKDEKI 233
K I + Q E K TK V+ +R +++ K K+ + +++
Sbjct: 2071 AKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRS 2130
Query: 234 KKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAP 293
+ K+ K+ + RK+ K + K+ E+ +R +D +E G
Sbjct: 2131 ELTKDEKK-----LARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 294 QVEAGKRLEELRRRRGETE----------------------SEEFEKLK---QKQQEAAL 328
+ E L+ R+R E + SEE E L +KQ+ +
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS 2245
Query: 329 ELEELKKKREERRK--VLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386
E EE +++ EER + V EEEE+R+++EE + K E+EE+ + K++ E+++ E EK +
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305
Query: 387 MPE----------DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQ 433
E + LSD+++ + S +EE + + ++K K Q
Sbjct: 2306 FEEKEEIMSEEETESLSDEEE-------EEESCSLEEEVDREKEILKKEKQFKLQEQ 2355
Score = 71.2 bits (173), Expect = 2e-12
Identities = 84/410 (20%), Positives = 183/410 (44%), Gaps = 51/410 (12%)
Query: 21 YQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 80
+Q++ +A ++ R+ + +R K+E + +V + + + V +E K
Sbjct: 1396 FQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATL--EEKVVKQEGKLVMIER 1453
Query: 81 ---------------QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 125
QV G+ ++ A +EE ++ LQE + + + + +
Sbjct: 1454 TPSWQDWKKAWDEWKQVHGETRKSWK---AWKEEWEKRLLQEEEKLHQAGEKLSPEEEML 1510
Query: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
++++ + + + E S+S++++Y+ EE T+ + R+ EE +++ E++
Sbjct: 1511 QEDKKLKWEEWK-QVWENMLSSKSKEQQYKDEEEVTLEEEVS----REGEEKEQQVTEEQ 1565
Query: 186 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK---------- 235
+E+ K I + + + Q +R+ QE++ ++E ++ +K
Sbjct: 1566 RHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQ 1625
Query: 236 -DKEPKEEVKSFMDRKKGFT---EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG 291
D+E + F +++ E SQ E + K K + + K+
Sbjct: 1626 DDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGK 1685
Query: 292 APQVE--AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERR----KVLE 345
+V+ +++EEL +R + +E E L Q+ +E ++EEL K EE K++E
Sbjct: 1686 LAEVKNILAQKVEELPQREQNLDWQEKE-LAQELEELEWDMEELSWKEEELNQEEGKLVE 1744
Query: 346 EEEQRRKQEEA----DRKLREEEEKRRLKEEIE-RRRAEAAEKRQKMPED 390
E+++ ++EEA KL EEE K +EE+ + + + A+ ++KMPE+
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794
Score = 70.5 bits (171), Expect = 4e-12
Identities = 93/414 (22%), Positives = 179/414 (43%), Gaps = 56/414 (13%)
Query: 97 REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEI 156
+E + ++ +AL++ + +T + + + E + ++ K + ++ +
Sbjct: 2068 KEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSE 2127
Query: 157 EETETVTKSYQKNDWRDAE-ENK------KEDKEKEEEEEEKPKRGSIGENQGEEKGTKV 209
+ +E +TK +K + + NK KE+K EEE + K + + EE G +
Sbjct: 2128 KRSE-LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEE 2186
Query: 210 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 269
+ E P K+ K ++ K+ +PKE+ S +D EV+S+ H +
Sbjct: 2187 E-------EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVD------EVESEE-----HFSE 2228
Query: 270 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ-QEAAL 328
E+ + S+ ++E E +R EE R E EE E+ ++++ +E +
Sbjct: 2229 EMESLLDELEKQESLSSEEEE--------EREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 329 ELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 388
E EE +KK++++ K EE +++ + E ++ EEE L +E E + + E+
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Query: 389 EDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYT 448
++ L +K+ FK + SL+ ER + + V G +A + + S L++
Sbjct: 2341 KEILKKEKQ-FKLQEQRRKSLRGRERVLSILRGVPHGKG-----RAIRLGVLKSPLKKLM 2394
Query: 449 SAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWE--KGNVFSSPTA-AGTPNKE 499
S K P +PVP + + WE K V P GT +KE
Sbjct: 2395 STALEMKEKTP-------VPVPEKQI-----SWEDKKATVVEIPRKFLGTMDKE 2436
Score = 69.7 bits (169), Expect = 7e-12
Identities = 95/439 (21%), Positives = 182/439 (41%), Gaps = 74/439 (16%)
Query: 22 QRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81
QR+ +E + AR R+RAR E+ ++ QEE L Q +++ + + EE K +
Sbjct: 1565 QRHIQEEHKWARIHRKRARAEK-KRAQEERKLAQEEEKL-AQEERQLAQEERKLAQAYVK 1622
Query: 82 VEGDD------EAAFL---ERLARREERRQKRLQEALERQK------------------- 113
+ DD E F E LA+R E+ + ++ +++K
Sbjct: 1623 ITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKK 1682
Query: 114 -----EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSE-------------SRQERYE 155
E + LP R D E E ++ E+ E +++E
Sbjct: 1683 GGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKL 1742
Query: 156 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEE---EEKPKRGSIGENQGEEKGTKVQAK 212
+EE + + + + W+ + +++E K +EEE +EK K E EE+ ++ K
Sbjct: 1743 VEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE-ERLGRK 1801
Query: 213 REKLQEDKPTFKKEEIK----DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ--------- 259
RE+L E K ++ + E++ K+K + K+ KK + K +
Sbjct: 1802 REQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLL 1861
Query: 260 -NGEFMTHKLKHTENTFSRPGG----RASVDTK-EAEGAPQVEAGKRLEELRRRRGETE- 312
N E +TH K ++ G A V+ K E ++ ++L E ++ + E
Sbjct: 1862 YNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVED 1921
Query: 313 --SEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLK 370
+++ EKL Q++ + ALE ++ K+ R ++ +E++ E R E+ K
Sbjct: 1922 SLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGK 1981
Query: 371 EEIERRRAEAAEKRQKMPE 389
E + + +++KM +
Sbjct: 1982 ETLSKGETPETSRQRKMTQ 2000
Score = 64.7 bits (156), Expect = 2e-10
Identities = 84/388 (21%), Positives = 166/388 (42%), Gaps = 44/388 (11%)
Query: 29 EEAARERRRRARQERLRQK----QEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 84
+E +++ ++ Q+ +Q Q+E +G++ ++ ++ + E T V+
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQ 1444
Query: 85 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKE 144
+ + +ER ++ + K +D + S + + E ++E
Sbjct: 1445 EGKLVMIERTPSWQDWK-----------KAWDEWKQVHGETRKSWKAWKEEWEKRLLQEE 1493
Query: 145 EKSESRQERYEIEETETVT-KSYQKNDWRDAEENKKEDKEKEEE--EEEKPKRGSIGENQ 201
EK E+ EE K + +W+ EN K KE++ +EE+ +
Sbjct: 1494 EKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSRE 1553
Query: 202 GEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG 261
GEEK +V ++ +QE E K +I + + E+ ++ +RK E K
Sbjct: 1554 GEEKEQQVTEEQRHIQE--------EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQE 1605
Query: 262 EFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQ 321
E +L E ++ + + D +E A A K EE +RGE S+E EKL Q
Sbjct: 1606 E---RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQK--EETLAQRGEKLSQEAEKLAQ 1660
Query: 322 KQQEAALELEELKKKRE----------ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 371
K+++ A + E++ ++ E E + +L ++ + Q E + +E+E + L E
Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL-E 1719
Query: 372 EIERRRAEAAEKRQKM--PEDGLSDDKK 397
E+E E + K +++ E L ++KK
Sbjct: 1720 ELEWDMEELSWKEEELNQEEGKLVEEKK 1747
Score = 64.3 bits (155), Expect = 3e-10
Identities = 54/236 (22%), Positives = 114/236 (48%), Gaps = 24/236 (10%)
Query: 27 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDD 86
DE++ AR++R+ A + R +EE+ + + +++ + DEE +E ++
Sbjct: 2135 DEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEE------EGGIEEEE 2188
Query: 87 EAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEK 146
FL+R R+ + ++ + + + D ++ S + ++ + E+ EE+
Sbjct: 2189 VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Query: 147 SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE---KEEEEEEKPKRGSIGENQGE 203
E R+E E EE E R+ EE +KE++E K+ E+EE+ K+ + + E
Sbjct: 2249 EE-REEEEEREEEEV----------REEEEERKEEEEGEEKQVEKEEEEKK----KKKKE 2293
Query: 204 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 259
+K +VQ K E +E + +EE + ++++E ++ +DR+K + + Q
Sbjct: 2294 KKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Score = 60.5 bits (145), Expect = 4e-09
Identities = 77/372 (20%), Positives = 158/372 (42%), Gaps = 35/372 (9%)
Query: 34 ERRRRARQERLRQKQE----EESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAA 89
E+R +E+L Q E EE + Q +++ V + + + Q + ++E
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVT 1545
Query: 90 FLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT-EKEEKSE 148
E ++R E ++ Q+ E Q+ A + R + A+ E +EE+
Sbjct: 1546 LEEEVSREGEEKE---QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKL 1602
Query: 149 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDK--EKEEEEEEKPKRGSIGENQGEEKG 206
+++ER +E + ++Y K D E + E K +KEE ++ ++ S + +K
Sbjct: 1603 AQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKR 1662
Query: 207 TKVQAKREKLQEDKPTFKKE-----EIKDEKIKKDKEPKEEVKSFMDRKKGFT------- 254
K+ K EK+ ++ K+ E+K+ +K +E + ++ ++K
Sbjct: 1663 KKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELE 1722
Query: 255 -----------EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 303
E+ + G+ + K K E + R + +E + A + E + +E
Sbjct: 1723 WDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKE 1782
Query: 304 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 363
+ E EE E+L +K+++ + +L +KRE R + EE + + +K
Sbjct: 1783 KLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRE--RWINSMEELTKNKMILYQKKNLA 1840
Query: 364 EEKRRLKEEIER 375
+EK+ L +E E+
Sbjct: 1841 QEKKNLAQEKEK 1852
Score = 56.2 bits (134), Expect = 8e-08
Identities = 54/205 (26%), Positives = 89/205 (43%), Gaps = 38/205 (18%)
Query: 26 DDEEEAARE---------RRRRARQERLRQKQEEESLGQVTDQVE-----VNAQNSVPDE 71
DDEEE E RR R R+E R + +E D+VE S+ DE
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 72 EAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRM 131
K + +++ E + E EER ++ ++E E +KE + +++
Sbjct: 2237 LEKQESLSSEEEEERE--------EEEEREEEEVREEEEERKEEEEG--------EEKQV 2280
Query: 132 QNDTAENETTEKEEKSESRQERYEI-EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEE 190
+ + E + +KE+K E QE+ E+ EE E + + D EE ++ +EE + E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Query: 191 KPKRGSIGENQGEEKGTKVQAKREK 215
K E +EK K+Q +R K
Sbjct: 2341 K-------EILKKEKQFKLQEQRRK 2358
Score = 52.8 bits (125), Expect = 8e-07
Identities = 85/409 (20%), Positives = 168/409 (41%), Gaps = 68/409 (16%)
Query: 27 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV---- 82
+EEEA +R + +E + QEEE L Q +++ + +P+EE + Q+
Sbjct: 1751 EEEEALAWQREKLSEEETKLAQEEELLIQEKEKL-AQHKEKMPEEEERLGRKREQLIEKK 1809
Query: 83 --------------------------------EGDDEAAFLERLARREERRQKRLQEALE 110
E + A E+LA+R+E +
Sbjct: 1810 MKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTH 1869
Query: 111 RQKEFDPTITDASL--SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 168
+K+ + + ++ + T E ET K+++ + E+ ++ +++ K +K
Sbjct: 1870 SKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEK 1929
Query: 169 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEI 228
A+E K EK + +K RG + + EEK ++ KR L E+K + +
Sbjct: 1930 L----AQEKMKLALEKAMVQGKKRLRGEL-DIAKEEKALNLEMKR--LAEEKMRLVEGK- 1981
Query: 229 KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 288
E + K + P+ R++ T+V+ E KL E +++ E
Sbjct: 1982 --ETLSKGETPE------TSRQRKMTQVEQ---ELFERKLSLEEKILLHEDRILAMEESE 2030
Query: 289 -AEGAPQVEAGKRLEELRRRRGETESEEF----EKLKQKQQEAALELEELKKKREERRKV 343
A+G + G+R+ +R+ S + E L ++ + L+ L+K + RK+
Sbjct: 2031 IAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKL 2090
Query: 344 LEEEEQRRKQEEA----DRKLREEEEKRRLKE-EIERRRAEAAEKRQKM 387
+EE + K + A +R+L E+ K +KE + +R+E + +K+
Sbjct: 2091 TQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKL 2139
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 51/180 (28%)
Query: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKT 75
L ++ Q + EEE RE +E +R+++EE +EE +
Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVREEEEERK----------------EEEEGE- 2276
Query: 76 TTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 135
QVE ++E +++++++K+ +E E+++ F+
Sbjct: 2277 ---EKQVEKEEE-------EKKKKKKEKKKEEVQEKEEVFE------------------- 2307
Query: 136 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 195
E E EE++ES + EE E + S ++ R+ E KKE + K +E+ K RG
Sbjct: 2308 -EKEEIMSEEETESLSD----EEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362
Score = 32.0 bits (71), Expect = 1.5
Identities = 46/225 (20%), Positives = 95/225 (42%), Gaps = 32/225 (14%)
Query: 217 QEDKPTFKKEEIKDEKIKKDKEP---KEE----VKSFMDRKKGFTEVKSQNGEFMTHKLK 269
+++KP F + ++K +P EE +K +++G VK + +++ LK
Sbjct: 1043 RDEKPAFSLDVSMPSELKSSLKPPTVSEESEVAIKPSKGQRRGQAGVKKHSQKWL-RGLK 1101
Query: 270 HTENTFSR-----PG--------GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316
T+ S+ PG A ++ +EA Q + + +L + + +S+E
Sbjct: 1102 KTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLSK---DVDSQEK 1158
Query: 317 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE------EEKRRLK 370
+ K L++++ KR+++ + +++ +K+ + + + EE E+ K
Sbjct: 1159 DISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEETTPPVMEQPVTKK 1218
Query: 371 EEIERRRAEAAEKRQKMPEDGLS--DDKKPFKCFTPKGSSLKIEE 413
+I+ R A R+ DG S DD GS K+ E
Sbjct: 1219 VKIQGRGASGISGRRSTAGDGSSWRDDLCRLMALRISGSQTKMSE 1263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.122 0.319
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,852,491
Number of Sequences: 37866
Number of extensions: 1305673
Number of successful extensions: 58041
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1232
Number of HSP's successfully gapped in prelim test: 1576
Number of HSP's that attempted gapping in prelim test: 9382
Number of HSP's gapped (non-prelim): 16422
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.