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Search of human proteins with 151108489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
(210 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151108489 TBC1 domain family, member 28 [Homo sapiens] 428 e-120
gi|239756750 PREDICTED: similar to TBC1 domain family, member 28... 420 e-118
gi|148235002 TBC1 domain family, member 26 [Homo sapiens] 354 3e-98
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 179 2e-45
gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 171 5e-43
gi|90577185 TBC1 domain family member 3C [Homo sapiens] 171 5e-43
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 171 5e-43
gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 169 1e-42
gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 169 1e-42
gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 169 1e-42
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 169 2e-42
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 166 1e-41
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ... 140 6e-34
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 127 9e-30
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 126 2e-29
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 60 1e-09
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 60 1e-09
gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 54 1e-07
gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 53 2e-07
gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 53 2e-07
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 52 4e-07
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 42 4e-04
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 40 0.002
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 39 0.003
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 36 0.021
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 35 0.060
gi|219555700 leucine rich repeat containing 27 isoform a [Homo s... 34 0.079
gi|55741567 leucine rich repeat containing 27 isoform a [Homo sa... 34 0.079
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso... 34 0.10
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 34 0.10
>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
Length = 210
Score = 428 bits (1100), Expect = e-120
Identities = 210/210 (100%), Positives = 210/210 (100%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV
Sbjct: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
Query: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120
SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI
Sbjct: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120
Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
Query: 181 NPVSIPGQRYSWYLCPYSQAWVSLGGVATS 210
NPVSIPGQRYSWYLCPYSQAWVSLGGVATS
Sbjct: 181 NPVSIPGQRYSWYLCPYSQAWVSLGGVATS 210
>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
[Homo sapiens]
Length = 234
Score = 420 bits (1079), Expect = e-118
Identities = 207/210 (98%), Positives = 207/210 (98%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
MEMD DP NLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELP V
Sbjct: 25 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
Query: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120
SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI
Sbjct: 85 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 144
Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 145 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 204
Query: 181 NPVSIPGQRYSWYLCPYSQAWVSLGGVATS 210
NPVSIPGQRYSWYLCPYSQAWVSLGGVATS
Sbjct: 205 NPVSIPGQRYSWYLCPYSQAWVSLGGVATS 234
>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
Length = 250
Score = 354 bits (908), Expect = 3e-98
Identities = 177/182 (97%), Positives = 178/182 (97%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
MEMD DP NLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV
Sbjct: 1 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
Query: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120
SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRV KVIPLAVRGRA SLLLDID+I
Sbjct: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120
Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
Query: 181 NP 182
NP
Sbjct: 181 NP 182
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 179 bits (453), Expect = 2e-45
Identities = 91/182 (50%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
M+M E+ D+L AQ + +I++ KY++GHRAG D G E V + + GI+HE ELP V
Sbjct: 1 MDMVENADSLQAQERKDILM-KYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPV 59
Query: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120
+A E K+ R+E RT+KW +ML +W Y+ + KL RV K IP+ +RG S+LL+I +I
Sbjct: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
K +NPG+Y++MKE+GKRSS IH I LDV TL+ H+ F R+G KQ+EL IL+AYS Y
Sbjct: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
Query: 181 NP 182
NP
Sbjct: 180 NP 181
>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
Length = 549
Score = 171 bits (432), Expect = 5e-43
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
Length = 549
Score = 171 bits (432), Expect = 5e-43
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 171 bits (432), Expect = 5e-43
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
Length = 549
Score = 169 bits (429), Expect = 1e-42
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I DVS TL+KH+ F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
Length = 549
Score = 169 bits (429), Expect = 1e-42
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I DVS TL+KH+ F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
Length = 549
Score = 169 bits (429), Expect = 1e-42
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I DVS TL+KH+ F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 169 bits (428), Expect = 2e-42
Identities = 88/167 (52%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GH+AG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHQAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 166 bits (421), Expect = 1e-41
Identities = 87/167 (52%), Positives = 114/167 (68%), Gaps = 5/167 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+ +++K +NPG+Y++MKEKG
Sbjct: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
K+SS I I DVS TL+KH+ F R+G KQ+EL IL+AY YNP
Sbjct: 136 KKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182
>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
[Homo sapiens]
Length = 424
Score = 140 bits (354), Expect = 6e-34
Identities = 73/149 (48%), Positives = 102/149 (68%), Gaps = 5/149 (3%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNNL---GIVHEMELPRVSALEVKQRRKESKRT 75
II KYE+GHRAG D G + Y NN+ G+ HE ELP ++A EVKQ R+E R
Sbjct: 18 IIMKYEKGHRAGLPEDKGPKPFG--SYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75
Query: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
+KW KML +W Y++++KL R + IP+ +RG S+LL+I++IK +NPG+Y++MKEKG
Sbjct: 76 SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135
Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFG 164
KRSS I + LDVS TL++H+ F R+G
Sbjct: 136 KRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 127 bits (318), Expect = 9e-30
Identities = 75/183 (40%), Positives = 106/183 (57%), Gaps = 5/183 (2%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVD--VRKYTNNLGIVHEMELP 58
M D+D AQ + I+ KY++G R GA ++ E D V K T+ G +HE ELP
Sbjct: 1 MNSDQDVALKLAQERAEIV-AKYDRG-REGAEIE-PWEDADYLVYKVTDRFGFLHEEELP 57
Query: 59 RVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDID 118
+ +Q+ E +RT KW KML W KY++T+K +R+ K IPL +RG +LLL+I
Sbjct: 58 DHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIP 117
Query: 119 KIKSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYS 178
K+K + Y +K + + S I I LDV+ T + H+MF R+GVKQQ L +L AYS
Sbjct: 118 KMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYS 177
Query: 179 AYN 181
YN
Sbjct: 178 IYN 180
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 126 bits (316), Expect = 2e-29
Identities = 70/165 (42%), Positives = 99/165 (60%), Gaps = 4/165 (2%)
Query: 19 IITKYEQGHRAGAAVDLGHEQVD--VRKYTNNLGIVHEMELPRVSALEVKQRRKESKRTN 76
I+ KY++G R GA ++ E D V K T+ G +HE ELP + +Q+ E +RT
Sbjct: 35 IVAKYDRG-REGAEIE-PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTT 92
Query: 77 KWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKGK 136
KW KML W KY++T+K +R+ K IPL +RG +LLL+I K+K + Y +K + +
Sbjct: 93 KWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRAR 152
Query: 137 RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYN 181
S I I LDV+ T + H+MF R+GVKQQ L +L AYS YN
Sbjct: 153 GCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN 197
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 60.5 bits (145), Expect = 1e-09
Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 3/112 (2%)
Query: 73 KRTNKWQKMLADWTKYRSTK--KLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKV 130
+R KW M ++W K+ S + K+ R K IP ++R +A L + ++ QNPGK++
Sbjct: 330 QRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEE 389
Query: 131 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
+ E+ + + I+ D+ H MF R G QQ+L IL AY+ Y P
Sbjct: 390 L-ERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRP 440
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 60.1 bits (144), Expect = 1e-09
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Query: 73 KRTNKWQKMLADWTKY--RSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKV 130
+R +KW ML +W K+ + KK+ R K IP ++RGRA L QNPGK+
Sbjct: 81 QRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDE 140
Query: 131 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
+ + + + I+ D+ H MF+ R G QQ+L +L AY+ Y P
Sbjct: 141 L-DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRP 191
>gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
Length = 617
Score = 53.5 bits (127), Expect = 1e-07
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 18/81 (22%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAA-----------------VDLGHEQVDV- 42
MEMDE PD LP QGQGNIIITKYEQ HR LGH ++
Sbjct: 37 MEMDEHPDILPTQGQGNIIITKYEQDHRVKTGSPCRQDPKPFTLPLSPWPSLGHRDAELG 96
Query: 43 RKYTNNLGIVHEMELPRVSAL 63
+++T ++ ++ P VS L
Sbjct: 97 QQWTQSMSVLTSGNSPVVSGL 117
>gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
Length = 339
Score = 53.1 bits (126), Expect = 2e-07
Identities = 25/36 (69%), Positives = 27/36 (75%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLG 36
MEMDE PD LP QGQGNIIITKYEQG +A +G
Sbjct: 1 MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMG 36
>gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
Length = 339
Score = 53.1 bits (126), Expect = 2e-07
Identities = 25/36 (69%), Positives = 27/36 (75%)
Query: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLG 36
MEMDE PD LP QGQGNIIITKYEQG +A +G
Sbjct: 1 MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMG 36
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 52.0 bits (123), Expect = 4e-07
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 73 KRTNKWQKMLADWTKYRST--KKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKV 130
+R KW +M + W K S KK+ + K IP A+R R LL + +PG Y+
Sbjct: 62 QREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQE 121
Query: 131 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
+ E + + I D+ H MF+ G QQ L +L AY+ Y P
Sbjct: 122 LAE-APGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRP 172
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 42.0 bits (97), Expect = 4e-04
Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Query: 72 SKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVM 131
++R KW ++L RS + + + V K +PL R R +L QNPG Y +
Sbjct: 40 TRRAIKWSRLLQGGGVPRS-RTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQL 98
Query: 132 KEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFG-VKQQELCDILVAYSAYN 181
+ G+R+ R+ I+ D++ T ++ F + Q+ L ++L+AY +N
Sbjct: 99 LQ-GERNPRLEDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHN 148
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 39.7 bits (91), Expect = 0.002
Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 75 TNKWQKMLADWTKYR---STKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVM 131
T W+KML+ + + +K+ V + +P RG L + +K Q P K +
Sbjct: 771 TTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPK 830
Query: 132 ----KEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYS 178
KE K+ + H I +D+ T H F + G Q L +IL AYS
Sbjct: 831 DVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYS 881
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 38.9 bits (89), Expect = 0.003
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 70 KESKRTNKWQKMLADWTK----YRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNP 125
KE + W+ A++ + YR T+K + V K IP ++RG LL K+ +P
Sbjct: 481 KEFLKEQAWKIHFAEYGQGICMYR-TEKTRELVLKGIPESMRGELWLLLSGAINEKATHP 539
Query: 126 GKYKVMKEKGK-RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
G Y+ + EK + + I+ D+ +L +H F G+ L +L AY+ NP
Sbjct: 540 GYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGI--AALRRVLTAYAFRNP 595
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 36.2 bits (82), Expect = 0.021
Identities = 45/202 (22%), Positives = 77/202 (38%), Gaps = 39/202 (19%)
Query: 3 MDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRVSA 62
+++ P NLPA+ + + E A ++ RK R+
Sbjct: 399 LEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRK--------------RIMK 444
Query: 63 LEVKQRRKESKRTNKW-QKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIK 121
KQ + W ++L +W RST+++ + + +P +VRG+ SL +
Sbjct: 445 ERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLA--VGNEL 502
Query: 122 SQNPGKYKVM----KEKGKRSSRI-----------------IHCIQLDVSHTLQKHMMFI 160
+ P Y++ KE+ K S + I+LD+S T +F
Sbjct: 503 NITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF- 561
Query: 161 QRFGVKQQELCDILVAYSAYNP 182
Q+ G L IL AY+ Y P
Sbjct: 562 QKGGPYHDVLHSILGAYTCYRP 583
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 34.7 bits (78), Expect = 0.060
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 91 TKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKY-KVMKEKGKRSSRIIHCIQLDV 149
T+K+ + V IP ++RGR L D + +PG Y +++E + + I+ D+
Sbjct: 495 TEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDL 554
Query: 150 SHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
+L +H F G+ L +L AY+ NP
Sbjct: 555 HRSLPEHPAFQNETGI--AALRRVLTAYAHRNP 585
>gi|219555700 leucine rich repeat containing 27 isoform a [Homo
sapiens]
Length = 530
Score = 34.3 bits (77), Expect = 0.079
Identities = 25/109 (22%), Positives = 58/109 (53%), Gaps = 13/109 (11%)
Query: 56 ELPRVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIP-----LAVRGRA 110
EL AL ++Q+R+E + +W++ + + +K + + K++P +A + +
Sbjct: 345 ELQEKQAL-MEQQRREKRALQEWRE------RAQRMRKRKEELSKLLPPRRSMVASKIPS 397
Query: 111 LSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQ-LDVSHTLQKHMM 158
+ L+D K+ PGK K KEK ++S+ + +Q ++ +++H++
Sbjct: 398 ATDLIDNRKVPLNPPGKMKPSKEKSPQASKEMSALQERNLEEKIKQHVL 446
>gi|55741567 leucine rich repeat containing 27 isoform a [Homo
sapiens]
Length = 530
Score = 34.3 bits (77), Expect = 0.079
Identities = 25/109 (22%), Positives = 58/109 (53%), Gaps = 13/109 (11%)
Query: 56 ELPRVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIP-----LAVRGRA 110
EL AL ++Q+R+E + +W++ + + +K + + K++P +A + +
Sbjct: 345 ELQEKQAL-MEQQRREKRALQEWRE------RAQRMRKRKEELSKLLPPRRSMVASKIPS 397
Query: 111 LSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQ-LDVSHTLQKHMM 158
+ L+D K+ PGK K KEK ++S+ + +Q ++ +++H++
Sbjct: 398 ATDLIDNRKVPLNPPGKMKPSKEKSPQASKEMSALQERNLEEKIKQHVL 446
>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
isoform b [Homo sapiens]
Length = 632
Score = 33.9 bits (76), Expect = 0.10
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 10/136 (7%)
Query: 51 IVHEMELPRVSALEVKQRRKESKRTNKWQKMLADWTKYRS---TKKLSQRVCKVIPLAVR 107
+ H L +++ +K++ KE W+ + A+ + S TKK V + IP +R
Sbjct: 438 VFHPQNLETLNSKMLKEKMKEQS----WKILFAECGRGVSMFRTKKTRDLVVRGIPETLR 493
Query: 108 GRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRI-IHCIQLDVSHTLQKHMMFIQRFGVK 166
G L + NP Y + E+ + + I+ D+ +L +H F G+
Sbjct: 494 GELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGI- 552
Query: 167 QQELCDILVAYSAYNP 182
L +L AY+ NP
Sbjct: 553 -SALRRVLTAYAYRNP 567
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 33.9 bits (76), Expect = 0.10
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 10/136 (7%)
Query: 51 IVHEMELPRVSALEVKQRRKESKRTNKWQKMLADWTKYRS---TKKLSQRVCKVIPLAVR 107
+ H L +++ +K++ KE W+ + A+ + S TKK V + IP +R
Sbjct: 438 VFHPQNLETLNSKMLKEKMKEQS----WKILFAECGRGVSMFRTKKTRDLVVRGIPETLR 493
Query: 108 GRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRI-IHCIQLDVSHTLQKHMMFIQRFGVK 166
G L + NP Y + E+ + + I+ D+ +L +H F G+
Sbjct: 494 GELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGI- 552
Query: 167 QQELCDILVAYSAYNP 182
L +L AY+ NP
Sbjct: 553 -SALRRVLTAYAYRNP 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,897,305
Number of Sequences: 37866
Number of extensions: 303858
Number of successful extensions: 776
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 722
Number of HSP's gapped (non-prelim): 57
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.