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Search of human proteins with 150378549
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150378549 tangerin [Homo sapiens]
(1523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150378549 tangerin [Homo sapiens] 2986 0.0
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens] 285 2e-76
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens] 285 2e-76
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens] 285 2e-76
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens] 285 3e-76
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 110 8e-24
gi|157738619 smoothelin-like 1 [Homo sapiens] 108 3e-23
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 103 1e-21
gi|209862793 microtubule associated monoxygenase, calponin and L... 103 2e-21
gi|170172518 microtubule associated monoxygenase, calponin and L... 101 6e-21
gi|209862789 microtubule associated monoxygenase, calponin and L... 101 6e-21
gi|19913396 smoothelin isoform b [Homo sapiens] 98 5e-20
gi|19913394 smoothelin isoform c [Homo sapiens] 95 5e-19
gi|19913398 smoothelin isoform a [Homo sapiens] 94 8e-19
gi|169234649 smoothelin-like 2 isoform 2 [Homo sapiens] 91 1e-17
gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens] 91 1e-17
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 90 2e-17
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 87 1e-16
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 87 1e-16
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 86 2e-16
gi|7662284 microtubule associated monoxygenase, calponin and LIM... 85 5e-16
gi|224451082 cytospin A [Homo sapiens] 85 6e-16
gi|224451080 cytospin A [Homo sapiens] 85 6e-16
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 84 8e-16
gi|118918413 MICAL C-terminal like [Homo sapiens] 84 1e-15
gi|4557241 actinin, alpha 3 [Homo sapiens] 83 2e-15
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 82 4e-15
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 82 4e-15
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 82 4e-15
gi|67782321 spectrin beta isoform a [Homo sapiens] 81 7e-15
>gi|150378549 tangerin [Homo sapiens]
Length = 1523
Score = 2986 bits (7741), Expect = 0.0
Identities = 1523/1523 (100%), Positives = 1523/1523 (100%)
Query: 1 MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP 60
MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP
Sbjct: 1 MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP 60
Query: 61 GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENESKGQRKVLATAEVDL 120
GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENESKGQRKVLATAEVDL
Sbjct: 61 GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENESKGQRKVLATAEVDL 120
Query: 121 ARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKPS 180
ARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKPS
Sbjct: 121 ARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKPS 180
Query: 181 DVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSN 240
DVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSN
Sbjct: 181 DVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSN 240
Query: 241 AEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAP 300
AEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAP
Sbjct: 241 AEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAP 300
Query: 301 TPAPRLRKGSDALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGP 360
TPAPRLRKGSDALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGP
Sbjct: 301 TPAPRLRKGSDALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGP 360
Query: 361 SIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGEAEESSA 420
SIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGEAEESSA
Sbjct: 361 SIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGEAEESSA 420
Query: 421 VCQVDAEQRSKVRHVDTKGPEATGVMPEARCRGTPEAPPRGSQGRLGVRTRDEAPSGLSL 480
VCQVDAEQRSKVRHVDTKGPEATGVMPEARCRGTPEAPPRGSQGRLGVRTRDEAPSGLSL
Sbjct: 421 VCQVDAEQRSKVRHVDTKGPEATGVMPEARCRGTPEAPPRGSQGRLGVRTRDEAPSGLSL 480
Query: 481 PPAEPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGIEGTGLEQGPSVGAISTRPQVSS 540
PPAEPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGIEGTGLEQGPSVGAISTRPQVSS
Sbjct: 481 PPAEPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGIEGTGLEQGPSVGAISTRPQVSS 540
Query: 541 WQGALLSTAQGAISRGLGGWEAEAGGSGDLETETEVVGLEVLGTQEKEVEGSGFPETRTL 600
WQGALLSTAQGAISRGLGGWEAEAGGSGDLETETEVVGLEVLGTQEKEVEGSGFPETRTL
Sbjct: 541 WQGALLSTAQGAISRGLGGWEAEAGGSGDLETETEVVGLEVLGTQEKEVEGSGFPETRTL 600
Query: 601 EIEILGALEKEAARSRVLESEVAGTAQCEGLETQETEVGVIETPGTETEVLGTQKTEAGG 660
EIEILGALEKEAARSRVLESEVAGTAQCEGLETQETEVGVIETPGTETEVLGTQKTEAGG
Sbjct: 601 EIEILGALEKEAARSRVLESEVAGTAQCEGLETQETEVGVIETPGTETEVLGTQKTEAGG 660
Query: 661 SGVLQTRTTIAETEVLVTQEISGDLGPLKIEDTIQSEMLGTQETEVEASRVPESEAEGTE 720
SGVLQTRTTIAETEVLVTQEISGDLGPLKIEDTIQSEMLGTQETEVEASRVPESEAEGTE
Sbjct: 661 SGVLQTRTTIAETEVLVTQEISGDLGPLKIEDTIQSEMLGTQETEVEASRVPESEAEGTE 720
Query: 721 AKILGTQEITARDSGVREIEAEIAESDILVAQEIEVGLLGVLGIETGAAEGAILGTQEIA 780
AKILGTQEITARDSGVREIEAEIAESDILVAQEIEVGLLGVLGIETGAAEGAILGTQEIA
Sbjct: 721 AKILGTQEITARDSGVREIEAEIAESDILVAQEIEVGLLGVLGIETGAAEGAILGTQEIA 780
Query: 781 SRDSGVPGLEADTTGIQVKEVGGSEVPEIATGTAETEILGTQEIASRSSGVPGLESEVAG 840
SRDSGVPGLEADTTGIQVKEVGGSEVPEIATGTAETEILGTQEIASRSSGVPGLESEVAG
Sbjct: 781 SRDSGVPGLEADTTGIQVKEVGGSEVPEIATGTAETEILGTQEIASRSSGVPGLESEVAG 840
Query: 841 AQETEVGGSGISGPEAGMAEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYE 900
AQETEVGGSGISGPEAGMAEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYE
Sbjct: 841 AQETEVGGSGISGPEAGMAEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYE 900
Query: 901 ALRAPVTQPRVLGSQEAKAEISGVQGSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMK 960
ALRAPVTQPRVLGSQEAKAEISGVQGSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMK
Sbjct: 901 ALRAPVTQPRVLGSQEAKAEISGVQGSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMK 960
Query: 961 VLESPENKSGTFKAQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEK 1020
VLESPENKSGTFKAQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEK
Sbjct: 961 VLESPENKSGTFKAQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEK 1020
Query: 1021 AEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFY 1080
AEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFY
Sbjct: 1021 AEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFY 1080
Query: 1081 PDKIDYASLDPLNIKQNNKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAF 1140
PDKIDYASLDPLNIKQNNKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAF
Sbjct: 1081 PDKIDYASLDPLNIKQNNKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAF 1140
Query: 1141 CTGQELQLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRA 1200
CTGQELQLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRA
Sbjct: 1141 CTGQELQLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRA 1200
Query: 1201 DGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNG 1260
DGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNG
Sbjct: 1201 DGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNG 1260
Query: 1261 EPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSP 1320
EPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSP
Sbjct: 1261 EPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSP 1320
Query: 1321 APGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQIDGR 1380
APGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQIDGR
Sbjct: 1321 APGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQIDGR 1380
Query: 1381 AAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFEL 1440
AAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFEL
Sbjct: 1381 AAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFEL 1440
Query: 1441 LSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLE 1500
LSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLE
Sbjct: 1441 LSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLE 1500
Query: 1501 RGLEQRRRKLSRQLSRRERCVLS 1523
RGLEQRRRKLSRQLSRRERCVLS
Sbjct: 1501 RGLEQRRRKLSRQLSRRERCVLS 1523
>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 285 bits (730), Expect = 2e-76
Identities = 146/265 (55%), Positives = 187/265 (70%), Gaps = 8/265 (3%)
Query: 1 MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP 60
M SVWKRLQRVGK A+KFQFVA Y EL++ECTKKWQPDKLVVVWTRR+RR SKAHSWQP
Sbjct: 1 MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQP 60
Query: 61 GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENES-KGQRKVLATAEVD 119
GI+NPYRG VVW VPEN++I+VTL++DPH +++E KEWTF+IENES G+RK LAT+ ++
Sbjct: 61 GIKNPYRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSSIN 120
Query: 120 LARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKP 179
+ ++A P+P Q V+L+ KP S KVV A L +LS + LREG+ATD+DMQSLASLMS+K
Sbjct: 121 MKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ 180
Query: 180 SDVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPS 239
+D+GNLDDF E +ED+ E +A + +L L E E++ P
Sbjct: 181 ADIGNLDDFEEDNEDDDENRVNQEEKA-AKITELINKLNFLDEAEKDLATVNSNPFDDPD 239
Query: 240 NAE------DTSPAPVSAPAPPART 258
AE S P++ A P +T
Sbjct: 240 AAELNPFGDPDSEEPITETASPRKT 264
Score = 217 bits (552), Expect = 8e-56
Identities = 126/241 (52%), Positives = 160/241 (66%), Gaps = 4/241 (1%)
Query: 1283 LKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEE 1342
L+K R RN FS D + ++ P D+++ + E
Sbjct: 922 LQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITE 981
Query: 1343 PPPSPGEEAGLQR-FQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQE 1401
P E+ L + F+DTSQYV EL ALE EQ+QID RAA VE +LR LM++G N +E
Sbjct: 982 TQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE 1041
Query: 1402 EVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQ 1461
E ++QEWF LVNKKNALIRR +QL LL +E DLERR+ELL+RELRAMLAIEDWQKT AQ+
Sbjct: 1042 EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQK 1101
Query: 1462 HREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKLSRQLSRRERCV 1521
REQLLL+ELV+LVN+RD LVRDLD +E+ A EEDE LER LEQ + K+++ + E+CV
Sbjct: 1102 RREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAK---KEEKCV 1158
Query: 1522 L 1522
L
Sbjct: 1159 L 1159
Score = 188 bits (477), Expect = 4e-47
Identities = 88/137 (64%), Positives = 111/137 (81%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
++SQSLL WC+EVT YRGV+ITNFTTSWRNGL+FCAILH F PD IDY SL+P +IK+N
Sbjct: 409 NASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKEN 468
Query: 1098 NKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQLEGGGGA 1157
NK+A+DGFA++G+SRLLEP+DMVLL++PDKL VMTYL QIRA +GQEL +VQ+E
Sbjct: 469 NKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSK 528
Query: 1158 GTYRVGSAQPSPPDDLD 1174
TY+VG+ + +D
Sbjct: 529 STYKVGNYETDTNSSVD 545
>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 285 bits (730), Expect = 2e-76
Identities = 146/265 (55%), Positives = 187/265 (70%), Gaps = 8/265 (3%)
Query: 1 MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP 60
M SVWKRLQRVGK A+KFQFVA Y EL++ECTKKWQPDKLVVVWTRR+RR SKAHSWQP
Sbjct: 1 MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQP 60
Query: 61 GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENES-KGQRKVLATAEVD 119
GI+NPYRG VVW VPEN++I+VTL++DPH +++E KEWTF+IENES G+RK LAT+ ++
Sbjct: 61 GIKNPYRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSSIN 120
Query: 120 LARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKP 179
+ ++A P+P Q V+L+ KP S KVV A L +LS + LREG+ATD+DMQSLASLMS+K
Sbjct: 121 MKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ 180
Query: 180 SDVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPS 239
+D+GNLDDF E +ED+ E +A + +L L E E++ P
Sbjct: 181 ADIGNLDDFEEDNEDDDENRVNQEEKA-AKITELINKLNFLDEAEKDLATVNSNPFDDPD 239
Query: 240 NAE------DTSPAPVSAPAPPART 258
AE S P++ A P +T
Sbjct: 240 AAELNPFGDPDSEEPITETASPRKT 264
Score = 217 bits (552), Expect = 8e-56
Identities = 126/241 (52%), Positives = 160/241 (66%), Gaps = 4/241 (1%)
Query: 1283 LKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEE 1342
L+K R RN FS D + ++ P D+++ + E
Sbjct: 922 LQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITE 981
Query: 1343 PPPSPGEEAGLQR-FQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQE 1401
P E+ L + F+DTSQYV EL ALE EQ+QID RAA VE +LR LM++G N +E
Sbjct: 982 TQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE 1041
Query: 1402 EVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQ 1461
E ++QEWF LVNKKNALIRR +QL LL +E DLERR+ELL+RELRAMLAIEDWQKT AQ+
Sbjct: 1042 EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQK 1101
Query: 1462 HREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKLSRQLSRRERCV 1521
REQLLL+ELV+LVN+RD LVRDLD +E+ A EEDE LER LEQ + K+++ + E+CV
Sbjct: 1102 RREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAK---KEEKCV 1158
Query: 1522 L 1522
L
Sbjct: 1159 L 1159
Score = 188 bits (477), Expect = 4e-47
Identities = 88/137 (64%), Positives = 111/137 (81%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
++SQSLL WC+EVT YRGV+ITNFTTSWRNGL+FCAILH F PD IDY SL+P +IK+N
Sbjct: 409 NASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKEN 468
Query: 1098 NKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQLEGGGGA 1157
NK+A+DGFA++G+SRLLEP+DMVLL++PDKL VMTYL QIRA +GQEL +VQ+E
Sbjct: 469 NKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSK 528
Query: 1158 GTYRVGSAQPSPPDDLD 1174
TY+VG+ + +D
Sbjct: 529 STYKVGNYETDTNSSVD 545
>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
Length = 1196
Score = 285 bits (730), Expect = 2e-76
Identities = 146/265 (55%), Positives = 187/265 (70%), Gaps = 8/265 (3%)
Query: 1 MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP 60
M SVWKRLQRVGK A+KFQFVA Y EL++ECTKKWQPDKLVVVWTRR+RR SKAHSWQP
Sbjct: 1 MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQP 60
Query: 61 GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENES-KGQRKVLATAEVD 119
GI+NPYRG VVW VPEN++I+VTL++DPH +++E KEWTF+IENES G+RK LAT+ ++
Sbjct: 61 GIKNPYRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSSIN 120
Query: 120 LARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKP 179
+ ++A P+P Q V+L+ KP S KVV A L +LS + LREG+ATD+DMQSLASLMS+K
Sbjct: 121 MKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ 180
Query: 180 SDVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPS 239
+D+GNLDDF E +ED+ E +A + +L L E E++ P
Sbjct: 181 ADIGNLDDFEEDNEDDDENRVNQEEKA-AKITELINKLNFLDEAEKDLATVNSNPFDDPD 239
Query: 240 NAE------DTSPAPVSAPAPPART 258
AE S P++ A P +T
Sbjct: 240 AAELNPFGDPDSEEPITETASPRKT 264
Score = 217 bits (552), Expect = 8e-56
Identities = 126/241 (52%), Positives = 160/241 (66%), Gaps = 4/241 (1%)
Query: 1283 LKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEE 1342
L+K R RN FS D + ++ P D+++ + E
Sbjct: 958 LQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITE 1017
Query: 1343 PPPSPGEEAGLQR-FQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQE 1401
P E+ L + F+DTSQYV EL ALE EQ+QID RAA VE +LR LM++G N +E
Sbjct: 1018 TQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE 1077
Query: 1402 EVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQ 1461
E ++QEWF LVNKKNALIRR +QL LL +E DLERR+ELL+RELRAMLAIEDWQKT AQ+
Sbjct: 1078 EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQK 1137
Query: 1462 HREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKLSRQLSRRERCV 1521
REQLLL+ELV+LVN+RD LVRDLD +E+ A EEDE LER LEQ + K+++ + E+CV
Sbjct: 1138 RREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAK---KEEKCV 1194
Query: 1522 L 1522
L
Sbjct: 1195 L 1195
Score = 188 bits (477), Expect = 4e-47
Identities = 88/137 (64%), Positives = 111/137 (81%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
++SQSLL WC+EVT YRGV+ITNFTTSWRNGL+FCAILH F PD IDY SL+P +IK+N
Sbjct: 409 NASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKEN 468
Query: 1098 NKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQLEGGGGA 1157
NK+A+DGFA++G+SRLLEP+DMVLL++PDKL VMTYL QIRA +GQEL +VQ+E
Sbjct: 469 NKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSK 528
Query: 1158 GTYRVGSAQPSPPDDLD 1174
TY+VG+ + +D
Sbjct: 529 STYKVGNYETDTNSSVD 545
>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
Length = 1231
Score = 285 bits (728), Expect = 3e-76
Identities = 132/196 (67%), Positives = 165/196 (84%), Gaps = 1/196 (0%)
Query: 1 MTSVWKRLQRVGKRAAKFQFVACYHELVLECTKKWQPDKLVVVWTRRNRRICSKAHSWQP 60
M SVWKRLQRVGK A+KFQFVA Y EL++ECTKKWQPDKLVVVWTRR+RR SKAHSWQP
Sbjct: 1 MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQP 60
Query: 61 GIQNPYRGTVVWMVPENVDISVTLYRDPHVDQYEAKEWTFIIENES-KGQRKVLATAEVD 119
GI+NPYRG VVW VPEN++I+VTL++DPH +++E KEWTF+IENES G+RK LAT+ ++
Sbjct: 61 GIKNPYRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSSIN 120
Query: 120 LARHAGPVPVQVPVRLRLKPKSVKVVQAELSLTLSGVLLREGRATDDDMQSLASLMSVKP 179
+ ++A P+P Q V+L+ KP S KVV A L +LS + LREG+ATD+DMQSLASLMS+K
Sbjct: 121 MKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ 180
Query: 180 SDVGNLDDFAESDEDE 195
+D+GNLDDF E +ED+
Sbjct: 181 ADIGNLDDFEEDNEDD 196
Score = 217 bits (552), Expect = 8e-56
Identities = 126/241 (52%), Positives = 160/241 (66%), Gaps = 4/241 (1%)
Query: 1283 LKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEE 1342
L+K R RN FS D + ++ P D+++ + E
Sbjct: 993 LQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITE 1052
Query: 1343 PPPSPGEEAGLQR-FQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQE 1401
P E+ L + F+DTSQYV EL ALE EQ+QID RAA VE +LR LM++G N +E
Sbjct: 1053 TQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE 1112
Query: 1402 EVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQ 1461
E ++QEWF LVNKKNALIRR +QL LL +E DLERR+ELL+RELRAMLAIEDWQKT AQ+
Sbjct: 1113 EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQK 1172
Query: 1462 HREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKLSRQLSRRERCV 1521
REQLLL+ELV+LVN+RD LVRDLD +E+ A EEDE LER LEQ + K+++ + E+CV
Sbjct: 1173 RREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAK---KEEKCV 1229
Query: 1522 L 1522
L
Sbjct: 1230 L 1230
Score = 188 bits (477), Expect = 4e-47
Identities = 88/137 (64%), Positives = 111/137 (81%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
++SQSLL WC+EVT YRGV+ITNFTTSWRNGL+FCAILH F PD IDY SL+P +IK+N
Sbjct: 444 NASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKEN 503
Query: 1098 NKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQLEGGGGA 1157
NK+A+DGFA++G+SRLLEP+DMVLL++PDKL VMTYL QIRA +GQEL +VQ+E
Sbjct: 504 NKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSK 563
Query: 1158 GTYRVGSAQPSPPDDLD 1174
TY+VG+ + +D
Sbjct: 564 STYKVGNYETDTNSSVD 580
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 110 bits (276), Expect = 8e-24
Identities = 99/332 (29%), Positives = 138/332 (41%), Gaps = 59/332 (17%)
Query: 1042 SLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQA 1101
+LL WC+ GYRGV I + ++S+R+GLAFCAILHR PD +D+ SL N+ +NN+ A
Sbjct: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
Query: 1102 FD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQ-IRAFCTGQELQLVQLEGGGGAGT 1159
F+ LG+ LL+P DMV +SVPD L +MTY+ Q FC+ G G
Sbjct: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCS---------PGQAGVSP 117
Query: 1160 YRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAGRASK 1219
R G A SPP A P EP++ A +G S+
Sbjct: 118 PRKGLAPCSPPS--------------VAPTPVEPEDVAQ----------GEELSSGSLSE 153
Query: 1220 DGGAEAPRESRPAEVPAEGLVNGAGAPG----GGGVRLRRPSVNGEPGSVPPPRAHGSF- 1274
G + P + A LV A G R RR S PG+ G+F
Sbjct: 154 QGTGQTPSSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFV 213
Query: 1275 -------------SHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPA 1321
S R + ++ + + + D P G +A A +A P +
Sbjct: 214 CAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKAS 273
Query: 1322 P-GPPTAADSQQPPG-----GSSPSEEPPPSP 1347
P P + PG S P+ P P+P
Sbjct: 274 PEARPQIPTKPRVPGKLQELASPPAGRPTPAP 305
Score = 93.6 bits (231), Expect = 1e-18
Identities = 89/363 (24%), Positives = 163/363 (44%), Gaps = 57/363 (15%)
Query: 1190 PQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGG 1249
P+ K A RA A+P +A AS+ +E P + + E L + + + G
Sbjct: 472 PKTKKRPAPRAPSASP-------LALHASRLSHSEPPSATPSPALSVESLSSESASQTAG 524
Query: 1250 GVRLRRPSVNGE--------PGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDP 1301
L P+V PG+ P + + S + + L + R +S +
Sbjct: 525 AELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPR 584
Query: 1302 DAGAMGAAAAE---GQAPDP-------SPAPGPPTAADSQQ-------------PPGGSS 1338
G+ G A+ G P P SP P P +++ Q P +S
Sbjct: 585 TRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAAS 644
Query: 1339 PSEEP---------PPSPGEEAGL-QRFQDTSQYVC-----AELQALEQEQRQIDGRAAE 1383
P+ + PP+PG L +R QY+ E+ +E+ ++ R
Sbjct: 645 PATKKATKGSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVL 704
Query: 1384 VEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSR 1443
+E +LR G N+ +E+ ++ +WF L+++K+ L+RR+ +L + ++Q+LE+R +
Sbjct: 705 LEEKLRG----GLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEY 760
Query: 1444 ELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGL 1503
ELR +L + T + RE++L++ELV+L+ QR+ ++ LD + EED+ LE +
Sbjct: 761 ELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMI 820
Query: 1504 EQR 1506
+++
Sbjct: 821 KKK 823
Score = 42.7 bits (99), Expect = 0.003
Identities = 62/271 (22%), Positives = 92/271 (33%), Gaps = 33/271 (12%)
Query: 209 PQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPARTSRGQGSERAN 268
P P S E K EEE + + ++A A+PS A TSPA + P G +
Sbjct: 413 PSPTASLESKPYNPFEEEEEDKEEEAPAAPSLA--TSPALGHPESTPKSLHPWYGITPTS 470
Query: 269 EAGGQVGPEAPRPPETSP-EMRSSR-QPAQDTAPTPAPRL------------RKGSDALR 314
+ P APR P SP + +SR ++ + TP+P L G++ L
Sbjct: 471 SPKTKKRP-APRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLE 529
Query: 315 PPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFGRQ 374
PP VPK+S P + G + P +E P
Sbjct: 530 PPA------VPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASP---- 579
Query: 375 RLKAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRSKVRH 434
+ R + +P SG G R+ S+ Q+ + K
Sbjct: 580 -----GLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENP 634
Query: 435 VDTK-GPEATGVMPEARCRGTPEAPPRGSQG 464
+ K P A+ +A P PP G
Sbjct: 635 FNRKPSPAASPATKKATKGSKPVRPPAPGHG 665
Score = 37.4 bits (85), Expect = 0.11
Identities = 41/164 (25%), Positives = 62/164 (37%), Gaps = 25/164 (15%)
Query: 1190 PQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRP-AEVPAEGLVNGAGAPGG 1248
P +P+ + A+P A R A R + + AP RP + + E LV AG+
Sbjct: 281 PTKPRVPGKLQELASPP-AGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSS- 338
Query: 1249 GGVRLRRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGA 1308
VNG +P P+ G+ +K D P + A
Sbjct: 339 --------LVNGRLHELPVPKPRGTPKPSEGTPAPRK-------------DPPWITLVQA 377
Query: 1309 AAAEGQAP-DPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEA 1351
+ AP PS +PGPP+ Q GG+ +P P+ E+
Sbjct: 378 EPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLES 421
Score = 36.6 bits (83), Expect = 0.19
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Query: 241 AEDTSPAPVSAPAPPART-SRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTA 299
AED P P+ A + G + + EA Q+ P PR P E+ S PA
Sbjct: 246 AEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQI-PTKPRVPGKLQELASP--PAG--R 300
Query: 300 PTPAPRLRKGSDALRPPVPQGEDEVPKASGAPPAGLGS 337
PTPAPR S PP P+ + + + AG S
Sbjct: 301 PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSS 338
Score = 31.2 bits (69), Expect = 8.0
Identities = 29/118 (24%), Positives = 42/118 (35%), Gaps = 12/118 (10%)
Query: 347 PQEGT---EAHGARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREA 403
P+EGT H ARLGP PF + + + ++ ED + G GG +
Sbjct: 207 PEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPG-------GGPSS 259
Query: 404 NTKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMPEAR--CRGTPEAPP 459
+ G A Q+ + R + + P A P R T APP
Sbjct: 260 SAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPP 317
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 108 bits (271), Expect = 3e-23
Identities = 127/441 (28%), Positives = 184/441 (41%), Gaps = 90/441 (20%)
Query: 775 GTQEIASRDSGVPG-LEADTTGIQV------KEVGGSEVPEIAT----GTAETEILGTQE 823
G QE A + G+ L+ + G+ +E GG E E G E +G+QE
Sbjct: 69 GKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQE 128
Query: 824 IASR-----SSGVPGLESEVAGAQETEVGGSGISGPEAGMAEARVLMTRKTEIIVPEA-- 876
+ R S E E A E + + PE+G +A K E P+A
Sbjct: 129 MTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQ-KADANDRDKPE---PKATV 184
Query: 877 EKEEAQTSGVQEAETRVGSAL----KYEALRAPVTQPRVLGSQEAKAEISGVQGSETQVL 932
E+E+A+T+ +E R + K A + + EAKAE G E
Sbjct: 185 EEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKE---- 240
Query: 933 RVQEAEAGVWGMSEGKSGAWGAQEAEMKVLESPENKSGTFKAQEAEAGVLGNEKGKEAEG 992
EA+ G ++ K A A+EAE S E + K E AGV+ + + E
Sbjct: 241 ---EAKHGAKEEADAKEEAEDAEEAEPGS-PSEEQEQDVEKEPEGGAGVIPSSPEEWPES 296
Query: 993 ------SLTEASLPEAQVASGAGAGAPRASSP-----------------EKAEEDR---- 1025
+L+ L VASG + + SSP EKA E R
Sbjct: 297 PTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEKAPERRVSAP 356
Query: 1026 ---RLPGSQ--------------APPALVSSSQS-----------LLEWCQEVTTGYRGV 1057
R P +Q P AL ++++ LLEWC+ +T Y V
Sbjct: 357 ARPRGPRAQNRKAIVDKFGGAASGPTALFRNTKAAGAAIGGVKNMLLEWCRAMTKKYEHV 416
Query: 1058 RITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQAFDGFAALG-VSRLLEP 1116
I NF++SW +G+AFCA++H+F+PD DYA LDP + N AF L ++LL+
Sbjct: 417 DIQNFSSSWSSGMAFCALIHKFFPDAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLDV 476
Query: 1117 ADMVLLSVPDKLIVMTYLCQI 1137
DMV L+VPD V TY+ ++
Sbjct: 477 DDMVRLAVPDSKCVYTYIQEL 497
Score = 47.4 bits (111), Expect = 1e-04
Identities = 70/319 (21%), Positives = 110/319 (34%), Gaps = 39/319 (12%)
Query: 256 ARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTPAPRLRKGSDALRP 315
AR Q + +E G V P A +PEM PA++T T + +G P
Sbjct: 15 AREKMEQKEGKLSEDGTTVSPAAD-----NPEMSGGGAPAEETKGTAGKAINEG-----P 64
Query: 316 PVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFGRQR 375
P G+ E PA G + E Q +A + + R ED
Sbjct: 65 PTESGKQE------KAPAEDGMSAELQGEANGLDEVKVESQREAGGKED-------AEAE 111
Query: 376 LKAEEMDTEDRP----EASGVDTEPRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRSK 431
LK E+ + E+ E +G E +S +EA K S + + + + + ++ Q++
Sbjct: 112 LKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKAD 171
Query: 432 VRHVDTKGPEATGVMPEARCRGTPEAPPRGS-QGRLGVRTRDEAPSGLSL-------PPA 483
D P+AT +A+ E R + DE S A
Sbjct: 172 ANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKA 231
Query: 484 EPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGI----EGTGLEQGPSVGAISTRPQVS 539
EP G+ GA+ A + E + PG + +E+ P GA
Sbjct: 232 EPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPE 291
Query: 540 SWQGALLSTAQGAISRGLG 558
W + + GLG
Sbjct: 292 EWPESPTGEGHNLSTDGLG 310
Score = 34.3 bits (77), Expect = 0.95
Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 22/163 (13%)
Query: 203 EARARVPQPDPSRELKTLCEEE----EEGQGRPQQAVASPS--NAEDTSPAPVSA----P 252
EA+A +PD E K +EE EE + + SPS +D P P
Sbjct: 228 EAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIP 287
Query: 253 APPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTPAPRL------ 306
+ P E N + +GP+ +TSP S +P +P
Sbjct: 288 SSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEK 347
Query: 307 ---RKGSDALRPPVPQGEDE---VPKASGAPPAGLGSARETQA 343
R+ S RP P+ ++ V K GA R T+A
Sbjct: 348 APERRVSAPARPRGPRAQNRKAIVDKFGGAASGPTALFRNTKA 390
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 103 bits (258), Expect = 1e-21
Identities = 69/192 (35%), Positives = 97/192 (50%), Gaps = 19/192 (9%)
Query: 1037 VSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQ 1096
+++ ++L +WC++ GYR V I N TTS+R+GLAFCAILHR PD I++++L NI +
Sbjct: 1 MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE 60
Query: 1097 NNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQLEGGG 1155
NNK AF LG+ LL+ DMV L VPD+L ++TY+ Q + G+ GG
Sbjct: 61 NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRS------PIGG 114
Query: 1156 GAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAG 1215
AG R P A A +L P A R +P A N V
Sbjct: 115 MAGVKRASEDSEEEPSGKKAPVQAAKL----------PSPAPARKPPLSP--AQTNPVVQ 162
Query: 1216 RASKDGGAEAPR 1227
R ++ G P+
Sbjct: 163 RRNEGAGGPPPK 174
Score = 85.5 bits (210), Expect = 4e-16
Identities = 98/371 (26%), Positives = 155/371 (41%), Gaps = 32/371 (8%)
Query: 1157 AGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAGR 1216
+G RVG+ P+ A G + L + QE +E A R + A R
Sbjct: 543 SGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAER 602
Query: 1217 ASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSH 1276
K A E R E P + V+G+ A G V + V P P P + G
Sbjct: 603 TLKPKEPRALAEPRAGEAPRK--VSGSFA---GSVHITLTPVR--PDRTPRPASPGPSLP 655
Query: 1277 VRDADLLKKRRSRLRNSSSFSMDD----PDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQ 1332
R RR RL +S + D P+ A + + P Q
Sbjct: 656 ARSPS--PPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKP--------HLQG 705
Query: 1333 PPGGSSPSEEPPPSPGEEAG----LQRFQDTSQYVCAELQALEQEQRQIDGRAAEVEMQL 1388
PG P PGE L + + + +LQ +E+ ++ R E+E +L
Sbjct: 706 KPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRL 765
Query: 1389 RSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAM 1448
R+ A E+ L+ +WF L+++K L+R++ +L + Q LE + + ELR +
Sbjct: 766 RAAEGDDA----EDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRL 821
Query: 1449 LAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQ--- 1505
+A + K+ ++ REQ LLE+ VS VN R ++V LD EED+ L +E+
Sbjct: 822 MAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGL 881
Query: 1506 RRRKLSRQLSR 1516
+R+K +LS+
Sbjct: 882 QRKKSKFRLSK 892
Score = 33.9 bits (76), Expect = 1.2
Identities = 45/181 (24%), Positives = 68/181 (37%), Gaps = 25/181 (13%)
Query: 256 ARTSRGQGSERANEAG----GQVGPEAPRPPETSPEMRSSR-QPAQDTAPTPAPRLRKGS 310
AR Q EAG G+ P P + P+ + + P + +PR+
Sbjct: 452 ARNFLKQALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLP 511
Query: 311 DALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGT----EAHGAR--------- 357
+ PP P +AS PPAG + E+ G+ EA A+
Sbjct: 512 SRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQD 571
Query: 358 LGPSIEDKGSGDPFG-RQRLKAEE----MDTEDRPEASGVDTEPRSGGREANTKRSGVRA 412
+ S+++ P G R LK + + +P+ EPR+G EA K SG A
Sbjct: 572 MSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAG--EAPRKVSGSFA 629
Query: 413 G 413
G
Sbjct: 630 G 630
Score = 33.5 bits (75), Expect = 1.6
Identities = 84/346 (24%), Positives = 112/346 (32%), Gaps = 50/346 (14%)
Query: 196 AHGPGAPEARARVPQPDPSR--ELKTLC---EEEEEGQGRPQQAVASPSNAEDTSPAPVS 250
A +P+ VP+ + + +T C + +E + RP + N SPA S
Sbjct: 244 AAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGN----SPARAS 299
Query: 251 APAPP--ARTSR--------GQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQ---- 296
PA P A TS + SE G PR +SP SS P
Sbjct: 300 VPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAA 359
Query: 297 ------DTAPTPAPRLRKGSDALRPPVPQ---GEDEVPKASGAPPAGLGSARET------ 341
+AP P P +G A R PQ A+ PPA SA T
Sbjct: 360 SHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNK 419
Query: 342 --QAQACPQEGTEAHGARLGPSI-----EDKGSGDPFGRQRLKA-EEMDTEDRPEASGVD 393
Q A P GT G PS+ K F +Q L A EE S
Sbjct: 420 FFQTSAVP-PGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPAT 478
Query: 394 TEPRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMPEARCRG 453
S + ++ A + SS + + T +P A R
Sbjct: 479 AAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRN 538
Query: 454 TPEAPPRGSQGRLGVRTRDEAP--SGLSLPPAEPAGHSGQLGDLEG 497
E+ G G G R + EAP G S + S Q G +G
Sbjct: 539 LAESSGVGRVG-AGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDG 583
>gi|209862793 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 2 [Homo sapiens]
Length = 1073
Score = 103 bits (256), Expect = 2e-21
Identities = 105/399 (26%), Positives = 154/399 (38%), Gaps = 73/399 (18%)
Query: 1023 EDRRLPGSQAPPAL-----VSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILH 1077
E L S+ P L V+ S LL WCQ T GY GV +T+ T SW++GLA CAI+H
Sbjct: 499 EMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIH 558
Query: 1078 RFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQ 1136
R+ PD ID+ SLD N+++NN+ AFD LG+S ++ +M + PDKL ++ YL Q
Sbjct: 559 RYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQ 618
Query: 1137 I--------------------RAFCTGQELQLVQLEGGGGAGTYRVGSAQPSPPDDLDAG 1176
+A + G R S + DLD
Sbjct: 619 FYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQTISRKRSPKDKKEKDLDGA 678
Query: 1177 GLAQRL---------RGHGAEGPQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPR 1227
G ++ RGH E P DR A V ++N V A++
Sbjct: 679 GKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVA--VGNQNKVKYMATQ--LLAKFE 734
Query: 1228 ESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRR 1287
E+ PA+ + G+ ++ P + PP RAHG RD
Sbjct: 735 ENAPAQ--SIGIRRQQREKECSRTCPKKVITLSPPPTPPPCRAHGGQQTYRDL------- 785
Query: 1288 SRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEEPPPSP 1347
DA G + + P+P P P Q S S P SP
Sbjct: 786 --------------DADNRGKQSPHHERPEPEP---PRRFFVDQWELSLSLRSSARPASP 828
Query: 1348 GEEAGLQRF--------QDTSQYVCAELQALEQEQRQID 1378
++ Q++ ++ + +LQ EQ + +D
Sbjct: 829 SSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKALLD 867
>gi|170172518 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 3 [Homo sapiens]
Length = 966
Score = 101 bits (251), Expect = 6e-21
Identities = 53/120 (44%), Positives = 73/120 (60%), Gaps = 6/120 (5%)
Query: 1023 EDRRLPGSQAPPAL-----VSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILH 1077
E L S+ P L V+ S LL WCQ T GY GV +T+ T SW++GLA CAI+H
Sbjct: 499 EMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIH 558
Query: 1078 RFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQ 1136
R+ PD ID+ SLD N+++NN+ AFD LG+S ++ +M + PDKL ++ YL Q
Sbjct: 559 RYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQ 618
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 101 bits (251), Expect = 6e-21
Identities = 53/120 (44%), Positives = 73/120 (60%), Gaps = 6/120 (5%)
Query: 1023 EDRRLPGSQAPPAL-----VSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILH 1077
E L S+ P L V+ S LL WCQ T GY GV +T+ T SW++GLA CAI+H
Sbjct: 499 EMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIH 558
Query: 1078 RFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQ 1136
R+ PD ID+ SLD N+++NN+ AFD LG+S ++ +M + PDKL ++ YL Q
Sbjct: 559 RYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQ 618
Score = 99.8 bits (247), Expect = 2e-20
Identities = 98/383 (25%), Positives = 161/383 (42%), Gaps = 35/383 (9%)
Query: 1147 QLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADR------A 1200
++ Q+E GA R S+ PS + R G+E P EA +
Sbjct: 1619 RMQQMELASGAPRPRKASSAPSQGKERRPDS-PTRPTLRGSEEPTLKHEATSEEVLSPPS 1677
Query: 1201 DGAAP--GVASRNAVAGRASKDGGAEAPR----------ESRPAEVPAEGLVNGAGAPGG 1248
D P S +G++ K +PR E RP E P+ L+ A A
Sbjct: 1678 DSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPK 1737
Query: 1249 G-------GVRLRRPSVNGEPGSVPPPRAHGSFSHVRDADL-LKKRRSRLRNSSSFSMDD 1300
G + + + P + + + L + + +LR SFS +D
Sbjct: 1738 SLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFS-ED 1796
Query: 1301 PDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTS 1360
D + Q P T + + + ++ ++ L+R +
Sbjct: 1797 SDLSSDDVLEKSSQKSRREPR----TYTEEELNAKLTRRVQKAARRQAKQEELKRLH-RA 1851
Query: 1361 QYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIR 1420
Q + +LQ +E+ QR+++ R VE LR E+G K + L+QEWF LV +KNA++R
Sbjct: 1852 QIIQRQLQQVEERQRRLEERGVAVEKALRG--EAGMGKKDDPKLMQEWFKLVQEKNAMVR 1909
Query: 1421 RQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDE 1480
+ +L + E +LE R L +ELR +A+ED KT + E+ +L E++ +V QRD
Sbjct: 1910 YESELMIFARELELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDS 1969
Query: 1481 LVRDLDHKERIALEEDERLERGL 1503
LV L+ + EED+ LE +
Sbjct: 1970 LVALLEEQRLREREEDKDLEAAM 1992
Score = 32.3 bits (72), Expect = 3.6
Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 18/104 (17%)
Query: 1252 RLRRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAA 1311
RL P GEP S+P PR+ R+ ++ R L +SS + + M +
Sbjct: 1388 RLGLPKPEGEPLSLPTPRSPSD----RELRSAQEERRELSSSSGLGLHGSSSN-MKTLGS 1442
Query: 1312 EGQAPDPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQR 1355
+ S PP++ PP PPP PGEE R
Sbjct: 1443 QSFNTSDSAMLTPPSS-----PP--------PPPPPGEEPATLR 1473
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 98.2 bits (243), Expect = 5e-20
Identities = 78/294 (26%), Positives = 119/294 (40%), Gaps = 24/294 (8%)
Query: 859 AEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYEALRAPVTQPRVLGSQEAK 918
A R L RK + ++++ + +QEA R G A + A
Sbjct: 610 AALRELRQRKRD------QRDKERERRLQEARGRPGEGRGNTATETTTRHSQRAADGSAV 663
Query: 919 AEISGVQ-----GSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMKVLESPENKSGTFK 973
+ ++ + T+ R E+ SE SG+ Q S + F
Sbjct: 664 STVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGSTMMQTKTFSSSSSSKKMGSIFD 723
Query: 974 AQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAP 1033
++ + G+ E + + L +AQ A R + EK E++ P
Sbjct: 724 REDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGAAGSPGGP 783
Query: 1034 PALVSSS------------QSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYP 1081
A V S Q LL+WC+ T GY V I NF++SW +G+AFCA++H F+P
Sbjct: 784 RAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFP 843
Query: 1082 DKIDYASLDPLNIKQNNKQAFDGFAA-LGVSRLLEPADMVLLSVPDKLIVMTYL 1134
+ DY L P N +QN + AF +LL+ DMV L PD V TY+
Sbjct: 844 EAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDMVRLREPDWKCVYTYI 897
Score = 45.8 bits (107), Expect = 3e-04
Identities = 93/372 (25%), Positives = 136/372 (36%), Gaps = 78/372 (20%)
Query: 189 AESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAP 248
AE+ A PG+PE P P P KT E +E P P
Sbjct: 221 AEAQCLTAEVPGSPE-----PPPSPP---KTTSPEPQESPTLPS---TEGQVVNKLLSGP 269
Query: 249 VSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTP---APR 305
PA + T ++RA+ AG PRP + S + S RQPAQ+ TP P
Sbjct: 270 KETPAAQSPTRGPSDTKRADVAG-------PRPCQRSLSVLSPRQPAQNRESTPLASGPS 322
Query: 306 LRKGSDALRPPVPQGEDEVPKAS----GAPPAG---------LGSARETQAQACPQEGTE 352
+ + ++R V + + P A+ G P A LG + + A G+
Sbjct: 323 SFQRAGSVRDRVHKFTSDSPMAARLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSS 382
Query: 353 AHG---ARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEP---RSGGREANTK 406
+ G S E +G P + R E+ P G+ P R+GG A ++
Sbjct: 383 SRGPSDTSSRFSKEQRGVAQPLAQLR----SCPQEEGPRGRGLAARPLENRAGGPVARSE 438
Query: 407 RSG----VRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATG--VMPEARCRGT----PE 456
G V G AE ++ + + D +G +TG ++P R
Sbjct: 439 EPGAPLPVAVGTAEPGGSM-----KTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLR 493
Query: 457 APP---RGSQGRLGVRTRDEAPSGLS-------------LPPAEPAGHSGQLGDLEGAR- 499
APP S G TR +P L+ PP+ G S ++ + E A
Sbjct: 494 APPTLLSTSSGGKSTITRVNSPGTLARLGSVTHVTSFSHAPPSSRGGCSIKM-EAEPAEP 552
Query: 500 -AAAGQEREGAE 510
AAA + GAE
Sbjct: 553 LAAAVEAANGAE 564
Score = 37.4 bits (85), Expect = 0.11
Identities = 59/289 (20%), Positives = 92/289 (31%), Gaps = 36/289 (12%)
Query: 200 GAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPS-----NAEDTSPAPVSAPAP 254
G P + +R + CE E + Q V+ P+ ++D + + AP
Sbjct: 135 GRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAP 194
Query: 255 PARTSRGQGSERANEAGGQVGPEAPRPPETSPEMR--SSRQPAQDTAPTPAPRLRKGSDA 312
P TS S ++ P +P PP E + ++ P P P+
Sbjct: 195 PGSTSSSPASPSSSPT-----PASPEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTS---- 245
Query: 313 LRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFG 372
P PQ +P G L S P+E A GPS D D G
Sbjct: 246 ---PEPQESPTLPSTEGQVVNKLLSG--------PKETPAAQSPTRGPS--DTKRADVAG 292
Query: 373 RQRLKAEEMDTEDRPEASGVDTEPRSGG----REANTKRSGVRAGEAEESSAVCQVDAEQ 428
+ + R A ++ P + G + A + R V ++ A D
Sbjct: 293 PRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARLQDGTP 352
Query: 429 R---SKVRHVDTKGPEATGVMPEARCRGTPEAPPRGSQGRLGVRTRDEA 474
+ S + GP T P + G+ P + R R A
Sbjct: 353 QAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVA 401
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 95.1 bits (235), Expect = 5e-19
Identities = 80/309 (25%), Positives = 125/309 (40%), Gaps = 25/309 (8%)
Query: 859 AEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYEALRAPVTQPRVLGSQEAK 918
A R L RK + ++++ + +QEA R G A + A
Sbjct: 610 AALRELRQRKRD------QRDKERERRLQEARGRPGEGRGNTATETTTRHSQRAADGSAV 663
Query: 919 AEISGVQ-----GSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMKVLESPENKSGTFK 973
+ ++ + T+ R E+ SE SG+ Q S + F
Sbjct: 664 STVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGSTMMQTKTFSSSSSSKKMGSIFD 723
Query: 974 AQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAP 1033
++ + G+ E + + L +AQ A R + EK E++ P
Sbjct: 724 REDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGAAGSPGGP 783
Query: 1034 PALVSSS------------QSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYP 1081
A V S Q LL+WC+ T GY V I NF++SW +G+AFCA++H F+P
Sbjct: 784 RAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFP 843
Query: 1082 DKIDYASLDPLNIKQNNKQAFDGFAAL-GVSRLLEPADMVLL-SVPDKLIVMTYLCQIRA 1139
+ DY L P N +QN + AF L L+E DM+++ PD V TY+ +
Sbjct: 844 EAFDYGQLSPQNRRQNFEVAFSSAEMLVDCVPLVEVDDMMIMGKKPDPKCVFTYVQSLYN 903
Query: 1140 FCTGQELQL 1148
EL+L
Sbjct: 904 HLRRHELRL 912
Score = 45.8 bits (107), Expect = 3e-04
Identities = 93/372 (25%), Positives = 136/372 (36%), Gaps = 78/372 (20%)
Query: 189 AESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAP 248
AE+ A PG+PE P P P KT E +E P P
Sbjct: 221 AEAQCLTAEVPGSPE-----PPPSPP---KTTSPEPQESPTLPS---TEGQVVNKLLSGP 269
Query: 249 VSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTP---APR 305
PA + T ++RA+ AG PRP + S + S RQPAQ+ TP P
Sbjct: 270 KETPAAQSPTRGPSDTKRADVAG-------PRPCQRSLSVLSPRQPAQNRESTPLASGPS 322
Query: 306 LRKGSDALRPPVPQGEDEVPKAS----GAPPAG---------LGSARETQAQACPQEGTE 352
+ + ++R V + + P A+ G P A LG + + A G+
Sbjct: 323 SFQRAGSVRDRVHKFTSDSPMAARLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSS 382
Query: 353 AHG---ARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEP---RSGGREANTK 406
+ G S E +G P + R E+ P G+ P R+GG A ++
Sbjct: 383 SRGPSDTSSRFSKEQRGVAQPLAQLR----SCPQEEGPRGRGLAARPLENRAGGPVARSE 438
Query: 407 RSG----VRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATG--VMPEARCRGT----PE 456
G V G AE ++ + + D +G +TG ++P R
Sbjct: 439 EPGAPLPVAVGTAEPGGSM-----KTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLR 493
Query: 457 APP---RGSQGRLGVRTRDEAPSGLS-------------LPPAEPAGHSGQLGDLEGAR- 499
APP S G TR +P L+ PP+ G S ++ + E A
Sbjct: 494 APPTLLSTSSGGKSTITRVNSPGTLARLGSVTHVTSFSHAPPSSRGGCSIKM-EAEPAEP 552
Query: 500 -AAAGQEREGAE 510
AAA + GAE
Sbjct: 553 LAAAVEAANGAE 564
Score = 37.4 bits (85), Expect = 0.11
Identities = 59/289 (20%), Positives = 92/289 (31%), Gaps = 36/289 (12%)
Query: 200 GAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPS-----NAEDTSPAPVSAPAP 254
G P + +R + CE E + Q V+ P+ ++D + + AP
Sbjct: 135 GRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAP 194
Query: 255 PARTSRGQGSERANEAGGQVGPEAPRPPETSPEMR--SSRQPAQDTAPTPAPRLRKGSDA 312
P TS S ++ P +P PP E + ++ P P P+
Sbjct: 195 PGSTSSSPASPSSSPT-----PASPEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTS---- 245
Query: 313 LRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFG 372
P PQ +P G L S P+E A GPS D D G
Sbjct: 246 ---PEPQESPTLPSTEGQVVNKLLSG--------PKETPAAQSPTRGPS--DTKRADVAG 292
Query: 373 RQRLKAEEMDTEDRPEASGVDTEPRSGG----REANTKRSGVRAGEAEESSAVCQVDAEQ 428
+ + R A ++ P + G + A + R V ++ A D
Sbjct: 293 PRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARLQDGTP 352
Query: 429 R---SKVRHVDTKGPEATGVMPEARCRGTPEAPPRGSQGRLGVRTRDEA 474
+ S + GP T P + G+ P + R R A
Sbjct: 353 QAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVA 401
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 94.4 bits (233), Expect = 8e-19
Identities = 77/291 (26%), Positives = 119/291 (40%), Gaps = 25/291 (8%)
Query: 859 AEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYEALRAPVTQPRVLGSQEAK 918
A R L RK + ++++ + +QEA R G A + A
Sbjct: 610 AALRELRQRKRD------QRDKERERRLQEARGRPGEGRGNTATETTTRHSQRAADGSAV 663
Query: 919 AEISGVQ-----GSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMKVLESPENKSGTFK 973
+ ++ + T+ R E+ SE SG+ Q S + F
Sbjct: 664 STVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGSTMMQTKTFSSSSSSKKMGSIFD 723
Query: 974 AQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAP 1033
++ + G+ E + + L +AQ A R + EK E++ P
Sbjct: 724 REDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGAAGSPGGP 783
Query: 1034 PALVSSS------------QSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYP 1081
A V S Q LL+WC+ T GY V I NF++SW +G+AFCA++H F+P
Sbjct: 784 RAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFP 843
Query: 1082 DKIDYASLDPLNIKQNNKQAFDGFAA-LGVSRLLEPADMVLLSVPD-KLIV 1130
+ DY L P N +QN + AF +LL+ DMV L PD K++V
Sbjct: 844 EAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDMVRLREPDWKMLV 894
Score = 45.4 bits (106), Expect = 4e-04
Identities = 89/376 (23%), Positives = 133/376 (35%), Gaps = 77/376 (20%)
Query: 199 PGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPA-- 256
P +P + P+P E E G P+ PS + TSP P +P P+
Sbjct: 202 PASPSSSPTPASPEPPLEPAEAQCLTAEVPGSPEPP---PSPPKTTSPEPQESPTLPSTE 258
Query: 257 ------------RTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTP-- 302
T Q R + PRP + S + S RQPAQ+ TP
Sbjct: 259 GQVVNKLLSGPKETPAAQSPHRGPSDTKRADVAGPRPCQRSLSVLSPRQPAQNRESTPLA 318
Query: 303 -APRLRKGSDALRPPVPQGEDEVPKAS----GAPPAG---------LGSARETQAQACPQ 348
P + + ++R V + + P A+ G P A LG + + A
Sbjct: 319 SGPSSFQRAGSVRDRVHKFTSDSPMAARLQDGTPQAALSPLTPARLLGPSLTSTTPASSS 378
Query: 349 EGTEAHG---ARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEP---RSGGRE 402
G+ + G S E +G P + R E+ P G+ P R+GG
Sbjct: 379 SGSSSRGPSDTSSRFSKEQRGVAQPLAQLR----SCPQEEGPRGRGLAARPLENRAGGPV 434
Query: 403 ANTKRSG----VRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATG--VMPEARCRGT-- 454
A ++ G V G AE ++ + + D +G +TG ++P R
Sbjct: 435 ARSEEPGAPLPVAVGTAEPGGSM-----KTTFTIEIKDGRGQASTGRVLLPTGNQRAELT 489
Query: 455 --PEAPP---RGSQGRLGVRTRDEAPSGLS-------------LPPAEPAGHSGQLGDLE 496
APP S G TR +P L+ PP+ G S ++ + E
Sbjct: 490 LGLRAPPTLLSTSSGGKSTITRVNSPGTLARLGSVTHVTSFSHAPPSSRGGCSIKM-EAE 548
Query: 497 GAR--AAAGQEREGAE 510
A AAA + GAE
Sbjct: 549 PAEPLAAAVEAANGAE 564
Score = 37.7 bits (86), Expect = 0.085
Identities = 59/289 (20%), Positives = 92/289 (31%), Gaps = 36/289 (12%)
Query: 200 GAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPS-----NAEDTSPAPVSAPAP 254
G P + +R + CE E + Q V+ P+ ++D + + AP
Sbjct: 135 GRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAP 194
Query: 255 PARTSRGQGSERANEAGGQVGPEAPRPPETSPEMR--SSRQPAQDTAPTPAPRLRKGSDA 312
P TS S ++ P +P PP E + ++ P P P+
Sbjct: 195 PGSTSSSPASPSSSPT-----PASPEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTS---- 245
Query: 313 LRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFG 372
P PQ +P G L S P+E A GPS D D G
Sbjct: 246 ---PEPQESPTLPSTEGQVVNKLLSG--------PKETPAAQSPHRGPS--DTKRADVAG 292
Query: 373 RQRLKAEEMDTEDRPEASGVDTEPRSGG----REANTKRSGVRAGEAEESSAVCQVDAEQ 428
+ + R A ++ P + G + A + R V ++ A D
Sbjct: 293 PRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARLQDGTP 352
Query: 429 R---SKVRHVDTKGPEATGVMPEARCRGTPEAPPRGSQGRLGVRTRDEA 474
+ S + GP T P + G+ P + R R A
Sbjct: 353 QAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVA 401
>gi|169234649 smoothelin-like 2 isoform 2 [Homo sapiens]
Length = 317
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/138 (39%), Positives = 78/138 (56%), Gaps = 14/138 (10%)
Query: 1001 EAQVASGAGAGAPRASSPEKAEEDRRLPGSQAPPALVSSS--QSLLEWCQEVTTGYRGVR 1058
E + A+G G G RA RL SQ+ +SS Q LLEWC+ T GY+ V
Sbjct: 179 EQETAAGKGKGEARA----------RLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVD 228
Query: 1059 ITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQAFDGFAAL-GVSRLLEPA 1117
+ NF++SW +G+AFCA++H F+PD DY SL P ++N + AF L RL+E
Sbjct: 229 LQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCERLIEVE 288
Query: 1118 DMVLLS-VPDKLIVMTYL 1134
DM+++ PD + V TY+
Sbjct: 289 DMMVMGRKPDPMCVFTYV 306
>gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens]
Length = 461
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/138 (39%), Positives = 78/138 (56%), Gaps = 14/138 (10%)
Query: 1001 EAQVASGAGAGAPRASSPEKAEEDRRLPGSQAPPALVSSS--QSLLEWCQEVTTGYRGVR 1058
E + A+G G G RA RL SQ+ +SS Q LLEWC+ T GY+ V
Sbjct: 323 EQETAAGKGKGEARA----------RLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVD 372
Query: 1059 ITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQAFDGFAAL-GVSRLLEPA 1117
+ NF++SW +G+AFCA++H F+PD DY SL P ++N + AF L RL+E
Sbjct: 373 LQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCERLIEVE 432
Query: 1118 DMVLLS-VPDKLIVMTYL 1134
DM+++ PD + V TY+
Sbjct: 433 DMMVMGRKPDPMCVFTYV 450
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 89.7 bits (221), Expect = 2e-17
Identities = 177/699 (25%), Positives = 260/699 (37%), Gaps = 119/699 (17%)
Query: 409 GVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMP-EARCRGTPEAPPRGSQGRLG 467
G G +E+ + Q+ QR + H D EA V P + T +G++G LG
Sbjct: 1677 GATRGPIKEAFDLQQI--LQRKRGEHTDG---EAAEVAPGKTHTDPTSTRTVQGAEGGLG 1731
Query: 468 VRTRDEAPSGLSLPPAEPAGHSGQ------------LGDLEGARAAAGQEREG------- 508
GLS P G G+ LG+ EG A QEREG
Sbjct: 1732 --------PGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGD--AMAQEREGKTHNSET 1781
Query: 509 -AEVRGGAPGIEGTGL-EQGPSVGAISTRPQVSSWQGALLSTAQGAISRGLGGWEAEAGG 566
A G EG G+ E+G + G S + A S G G EA
Sbjct: 1782 SAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEA- 1840
Query: 567 SGDLETETEVVGLEVLGTQEKEVEGSGFPETRTLEI-EILGALEKEAARSRVLESEVAGT 625
G+ + E+E V +E EG PE+ +E E G + E+ E+E
Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQ 1900
Query: 626 AQCEGLETQETE---------VGVIETPGT-ETEVLGTQKTEAGGSGVLQTRTTIAETEV 675
+ EG E E E V +ET G E E G + EA + T E+EV
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960
Query: 676 LVTQEI-------SGDLGPLKIEDTIQSEMLGTQETEVEASRVPESEAEGTEAKILGTQE 728
+ +QE S D+ L++E Q E G + E E PE+E E EA+ +E
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQ-EAEGEAQPESEDVEAPEAEGEMQEAE----EE 2015
Query: 729 ITARDSGV-----------REIEAEIA--------ESDILVAQEIEVGLLGVLGIETGAA 769
GV +E+E E ESD + A E E G E A
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEG-EVQEA 2074
Query: 770 EGAILGTQEIASRDSGVPGLEADTTGIQVKEVGGS-------EVPEIATGTAETEILGTQ 822
EG E + ++ G++ E G E PE G A+ E G +
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE-TEGEAQPESEGIE 2133
Query: 823 EIASRSSGVPGLESEVAGAQETEVGGSGISGPEAGMAEARVLMTRKTEIIVPEAEKE-EA 881
A + G ESE AQ+ E G + PE+ EA+ EAE+E +
Sbjct: 2134 --APEAEGEAQPESEGVEAQDAE----GEAQPESEGIEAQ------------EAEEEAQP 2175
Query: 882 QTSGVQEAETRVGSALKYEALRAPVTQPRVLGSQEAKAEISGVQGSETQVLRVQEAEAGV 941
+ GV+ E + + E + AP + EA+ E+ GV+ E + E E
Sbjct: 2176 ELEGVEAPEAEGEAQPESEGIEAPEAEG------EAQPELEGVEAPEAEEEAQPEPEGVE 2229
Query: 942 WGMSEGKSGAWGAQEAEMKVLESPENKSGTFKAQEAEAGVLGNEKGKEAEGSLTEASLPE 1001
+EG++ E + + SP+ G +++EA + + P
Sbjct: 2230 TPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPH 2289
Query: 1002 AQVASGAGAGAPRASS-----PEKAEEDRRLPGSQAPPA 1035
+ S G + RASS + +E D L +++P A
Sbjct: 2290 QRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDA 2328
Score = 76.6 bits (187), Expect = 2e-13
Identities = 120/504 (23%), Positives = 185/504 (36%), Gaps = 67/504 (13%)
Query: 160 EGRATDDDMQSLASLMSVKPSDVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKT 219
+G +D++Q A+ D G D + EA G PE+ V P+ +
Sbjct: 1806 QGSGHEDNLQGEAAAGG--DQDPGQSDGAEGIEAPEAEGEAQPESEG-VEAPEAEGDA-- 1860
Query: 220 LCEEEEEGQGRPQ-QAVASPSNAEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEA 278
+E EG+ +P+ + V +P + P P A E E+ G PEA
Sbjct: 1861 ---QEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEW------EVQPESEGAEAPEA 1911
Query: 279 PRPPETSPEMRSSRQPAQDTAPTPAPRLRKGSDALRPPVPQGEDEVPKASGA--PPAGLG 336
+ E PE S A +T P +G++A + E+ +A G P + +
Sbjct: 1912 EK--EAQPETESVE--ALETEGEDEPE-SEGAEA-----QEAEEAAQEAEGQTQPESEVI 1961
Query: 337 SARETQAQACPQ-EGTEAHGARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTE 395
++E + +A P+ E EA + E +G P E + E + + + +
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQ-EAEGEAQPESED---VEAPEAEGEMQEAEEEAQ 2017
Query: 396 PRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRS---KVRHVDTKGPEATGVMPEARCR 452
P S G EA K G A E E + + DA+ S + + + EA G + EA
Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077
Query: 453 GTPEAPPRGSQGRLGVRTRDEAPSGLSLPPAEPAGHSGQLGDLEGARAAAGQEREGAEVR 512
PE+ +Q G + G+ P AE + + A E EG E
Sbjct: 2078 AHPESEDVDAQEAEGEAQPES--EGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIE-- 2133
Query: 513 GGAPGIEGTGLEQGPSVGAISTRPQVSSWQGALLSTAQGAISRGLGGWEAEAGGSGDLET 572
AP EG + V A + S G+ EAE +LE
Sbjct: 2134 --APEAEGEAQPESEGVEAQDAEGEAQ------------PESEGIEAQEAEEEAQPELE- 2178
Query: 573 ETEVVGLEVLGTQEKEVEGSGFPETRTLEI-EILGALEKEAARSRVLESEVAGTAQCEGL 631
G + E EG PE+ +E E G + E E+E + EG+
Sbjct: 2179 ----------GVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV 2228
Query: 632 ETQETEVGVIETPGTETEVLGTQK 655
ET E E P +E E G +K
Sbjct: 2229 ETPEAEGEA--QPESEGETQGEKK 2250
Score = 68.2 bits (165), Expect = 6e-11
Identities = 78/313 (24%), Positives = 119/313 (38%), Gaps = 46/313 (14%)
Query: 189 AESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAP 248
AE + EA PE+ QP K+ EE +E +G Q+ D P
Sbjct: 2005 AEGEMQEAEEEAQPESDGVEAQP------KSEGEEAQEVEGETQKTEG------DAQPES 2052
Query: 249 VSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTP-APRLR 307
AP A + EA G+ PE+ + E QP + P A
Sbjct: 2053 DGVEAPEAEEEAQEAEGEVQEAEGEAHPESE--DVDAQEAEGEAQPESEGVEAPEAEGEA 2110
Query: 308 KGSDALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQ-EGTEAHGARLGPSIEDKG 366
+ ++ + P +GE + P++ G A E + +A P+ EG EA A E +G
Sbjct: 2111 QKAEGIEAPETEGEAQ-PESEGI------EAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163
Query: 367 SGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGEAE-----ESSAV 421
++A+E + E +PE GV+ G EA + G+ A EAE E V
Sbjct: 2164 ---------IEAQEAEEEAQPELEGVEAPEAEG--EAQPESEGIEAPEAEGEAQPELEGV 2212
Query: 422 CQVDAEQRSKVRHVDTKGPEATG-VMPEA------RCRGTPEAPPRGSQGRLGVRTRDEA 474
+AE+ ++ + PEA G PE+ +G+P+ Q +
Sbjct: 2213 EAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPV 2272
Query: 475 PSGLSLPPAEPAG 487
P PP P G
Sbjct: 2273 PEDRPTPPPSPGG 2285
Score = 62.8 bits (151), Expect = 2e-09
Identities = 174/797 (21%), Positives = 262/797 (32%), Gaps = 138/797 (17%)
Query: 348 QEGTEAHGARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREANTKR 407
+EG + G +L + E +G G +L+ E + + GV E G E +
Sbjct: 1328 EEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQG 1387
Query: 408 SGVRAGEAEES-SAVCQVDAEQRSKVRHVDTKG-PEATGVMPEARCRGTPEAPPRGSQGR 465
+ G EE V ++ S+ D KG E V E R + A P ++G
Sbjct: 1388 EALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEG- 1446
Query: 466 LGVRTRDEAPSGLSLPPAEPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGIEGTGLEQ 525
+ P EP H + R + Q G E GA + +
Sbjct: 1447 -------------TEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQA 1493
Query: 526 GPSVGAISTRPQVSS---------WQGALLSTAQGAISRGLGGWEAEAGGSGDLE----- 571
P+ GA V+ W LL + A L AE L+
Sbjct: 1494 QPTQGAAERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLL 1553
Query: 572 ------------------TETEVVGLE-------------------VLGTQEKEVEGSGF 594
T+ E+ L+ +L TQ++ G
Sbjct: 1554 DQMAAELQQDVAQRLQDSTKRELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGL 1613
Query: 595 PETRTLEIEILG------ALEKEAARSRVLESEVAGTAQCEGLETQETEVGVIETPGTET 648
LG LE E A S L S++ A+ E E V +P +
Sbjct: 1614 RNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPK 1673
Query: 649 EVLGT--------------------QKTEAGGSGVLQTRTTIAETEVLVTQEISGDLGP- 687
+G + T+ + V +T T Q G LGP
Sbjct: 1674 ATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPG 1733
Query: 688 -------LKIEDTIQSEMLGTQETEVEASRVPESEAEGTEAKILGTQEITARDSGVREIE 740
+ ED S+ L + ++ A+ E K ++ + G E E
Sbjct: 1734 LSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQE 1793
Query: 741 AEIAESDILVAQEIEVGLLGVLGIETGAAEGAILGTQEIASRDSGVPGLEA-DTTGIQVK 799
E +++ E G G G E A G + + G G+EA + G
Sbjct: 1794 GE------GISERGETGGQG-SGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQP 1846
Query: 800 EVGGSEVPEI------ATGTAETEILGTQEIASRSSGVPGLESEVAGAQETEVGGSGISG 853
E G E PE A G A+ E + + P E E EV G
Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPES-EG 1905
Query: 854 PEAGMAEARVL-MTRKTEIIVPEAEKE-EAQTSGVQEAETRVGSALKYEALRAPVTQPRV 911
EA AE T E + E E E E++ + QEAE +A + E P + V
Sbjct: 1906 AEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE---AAQEAEGQTQP--ESEV 1960
Query: 912 LGSQEAKAEISGVQGSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMKVLESPEN---- 967
+ SQEA+ E + + + + L V+ G ++ +S A EAE ++ E+ E
Sbjct: 1961 IESQEAEEE-AQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPE 2019
Query: 968 --------KSGTFKAQEAEAGVLGNEKGKEAEGSLTEA--SLPEAQVASGAGAGAPRASS 1017
KS +AQE E E + E EA + EAQ A G A +
Sbjct: 2020 SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAH 2079
Query: 1018 PEKAEEDRRLPGSQAPP 1034
PE + D + +A P
Sbjct: 2080 PESEDVDAQEAEGEAQP 2096
Score = 59.7 bits (143), Expect = 2e-08
Identities = 80/338 (23%), Positives = 133/338 (39%), Gaps = 34/338 (10%)
Query: 189 AESDEDEAHGPGAPEAR---ARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTS 245
AE + EA G PE+ A+ + + E + + E EG+ + + + +P +
Sbjct: 2067 AEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQ 2126
Query: 246 PAPVSAPAPPARTSRGQGSE--RANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTAPTPA 303
P AP A SE A +A G+ PE+ E + + AP
Sbjct: 2127 PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAE 2186
Query: 304 PRLRKGSDALRPPVPQGEDEVPKASG--APPAGLGSARETQAQACPQ--EGTEAHGARLG 359
+ S+ + P +GE + P+ G AP A E +AQ P+ E EA G
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQ-PELEGVEAPEA------EEEAQPEPEGVETPEAEG-EAQ 2238
Query: 360 PSIEDKGSGDPFGRQRL-----KAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGE 414
P E + G+ G ++ ++EE P T P S G + +R G + G
Sbjct: 2239 PESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGP 2298
Query: 415 AEESSAVCQVDAEQRSKVRHV--DTKGPEATGVMPEARCRGTPEAPPRGSQ--GRLGVRT 470
+ ++ ++ S+ HV DT+ P+A+ GTP A + ++
Sbjct: 2299 SSSRASSWGNCWQKDSENDHVLGDTRS-------PDAKSTGTPHAERKATRMYPESSTSE 2351
Query: 471 RDEAPSGLSLPPAEPAGHSGQLGDLEGARAAAGQEREG 508
++EAP G S P + A L + + + A E G
Sbjct: 2352 QEEAPLG-SRTPEQGASEGYDLQEDQALGSLAPTEAVG 2388
Score = 47.8 bits (112), Expect = 8e-05
Identities = 200/947 (21%), Positives = 324/947 (34%), Gaps = 139/947 (14%)
Query: 491 QLGDLEGARAAAGQEREGAEVR----GGAPGIEGTGLEQGPSVGAISTRPQVSSWQGALL 546
QL ++E G + EG ++ G G++G LE+G + V + +
Sbjct: 1355 QLEEIEET-GGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEA 1413
Query: 547 STAQGAISRGLGGWEAEAGGSGDLETETEVVGLEVLGTQEKEVEGSGFPETRTLEIEILG 606
S+ G S+ + E G E GT+E S ET E
Sbjct: 1414 SSPDGKGSQEDDPVQEEEAGRASASAEP----CPAEGTEEPTEPPSHLSETDPSASERQS 1469
Query: 607 ALEKEAARSRVLESEVAGTAQCEGLETQ---ETEVGVIETPGTETEVLGT----QKTE-- 657
+ E + + + G + TQ E V + + + + +KTE
Sbjct: 1470 GSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLLKKTEKA 1529
Query: 658 -----AGGSGVLQTRTTIAETEVL--VTQEISGDLGPLKIEDTIQSEMLGTQETEVEASR 710
A L+ R + + ++L + E+ D+ +++D+ + E+ Q
Sbjct: 1530 FLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQ-RLQDSTKRELQKLQGRAGRMVL 1588
Query: 711 VPESEAEGTEAKILGTQEITARDSGVREIEA----EIAESDILVAQEIEVGLLGVLGIET 766
P EA E +L TQ+ R G+R + A + + E E L LG +
Sbjct: 1589 EPPREALTGEL-LLQTQQRRHRLRGLRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQL 1647
Query: 767 GA-AEGAILGTQEIASRDSGVPGLEADTTGIQ---VKEV--------------GGSEVPE 808
G AEG E R P T G +KE E E
Sbjct: 1648 GEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAE 1707
Query: 809 IATGTAETEILGTQEIASRSSGV-PGLESEVAGAQETEVGGSGISGPEAGMAEARVLMTR 867
+A G T+ T+ + G+ PGL G G+ E G R+ +
Sbjct: 1708 VAPGKTHTDPTSTRTVQGAEGGLGPGLSQ-----------GPGVDEGEDGEGSQRLNRDK 1756
Query: 868 KTEIIVPEAEKEEAQTSG-VQEAETRVGSALKYEALRAPVTQPRVLGSQEAKAEISGVQG 926
++ E + + G +ET GS L + G ++ +G QG
Sbjct: 1757 DPKLGEAEGDAMAQEREGKTHNSETSAGSELG---------EAEQEGEGISERGETGGQG 1807
Query: 927 SETQVLRVQEAEAGVW---GMSEGKSG-----AWGAQEAEMKVLESPENKSGTFKAQEAE 978
S + EA AG G S+G G A G + E + +E+PE + AQEAE
Sbjct: 1808 SGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGD---AQEAE 1864
Query: 979 A-------GVLGNEKGKEAEGSLTEASLPEAQ---VASGAGAGAPRASSPEKAE----ED 1024
V E EA+ + PEA+ GA AP A + E E
Sbjct: 1865 GEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA 1924
Query: 1025 RRLPGSQAPPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKI 1084
G P + + +Q E QE T + P+
Sbjct: 1925 LETEGEDEPESEGAEAQEAEEAAQEAE---------GQTQPESEVIESQEAEEEAQPESE 1975
Query: 1085 DYASLDPLNIKQNNKQAFDGFAALGVSRLLEP-ADMVLLSVPDKLIVMTYLCQIRAFCTG 1143
D ++ L ++ ++A +G A + P A+ + ++ + + + G
Sbjct: 1976 D---VEALEVEVETQEA-EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEG 2031
Query: 1144 QELQLVQLEGG---GGAGTYRVGSAQPSPPDDL-DAGGLAQRLRG--HGAEGPQEPKEAA 1197
+E Q V+ E G A G P ++ +A G Q G H + +EA
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Query: 1198 DRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGL----VNGAGAPGGGGVRL 1253
A + GV + A G A K G EAP A+ +EG+ G P GV
Sbjct: 2092 GEAQPESEGVEAPEA-EGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEA 2150
Query: 1254 RRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMD---DPDAGAMGAAA 1310
+ +P S + + ++ + L + + P++ + A
Sbjct: 2151 QDAEGEAQPES----------EGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPE 2200
Query: 1311 AEGQA-PDPSPAPGPPTAADSQQPPGG----SSPSEEPPPSPGEEAG 1352
AEG+A P+ P ++Q P G + E P S GE G
Sbjct: 2201 AEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQG 2247
Score = 46.6 bits (109), Expect = 2e-04
Identities = 103/424 (24%), Positives = 151/424 (35%), Gaps = 90/424 (21%)
Query: 195 EAHGPGAPEARARVPQPDPSREL------------KTLCEEEEEGQGRPQQAVASPS--- 239
+ H P +VP+P R + + G RP + + PS
Sbjct: 673 DTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDL 732
Query: 240 ---NAEDTSPAP----VSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSR 292
++ +PA VS +P S G A +AG + AP PP TS S
Sbjct: 733 LGTSSATVTPAVHSDFVSGVSPHNAPSAGW----AGDAGSRTCSPAPIPPHTSDSCSKSG 788
Query: 293 QPA--QDTAPTPAPRLRKGSDALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEG 350
+ ++ TP P S L V + E G+ ++ C Q G
Sbjct: 789 AASLGEEARDTPQP-----SSPLVLQVGRPEQ-------------GAVGPHRSHCCSQPG 830
Query: 351 TE-AHGARLGPSIEDKG----------SGDPFGRQRLKA-EEMDTEDRPEASGVDTEPRS 398
T+ A A+ GPS E G P ++R + + + A G P+
Sbjct: 831 TQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQE 890
Query: 399 GGREAN-TKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKG-----PEATGVMPEARCR 452
G R+ T G +G + SSA + S+ + + + G EA+GV P + R
Sbjct: 891 GTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGVSPSSLPR 950
Query: 453 GTPEA-----------PPRGSQGRLGVRTRDEAPSGLSLPPAEPAGHSGQLGDLEGARAA 501
+PEA P L T A GL P +P G LEG
Sbjct: 951 SSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDP----GDDHSLEGLGEP 1006
Query: 502 AGQEREGAEVRGGAPGIEGTGLEQGPSVGAISTRPQVSSWQGALLSTAQGAISRGLGGWE 561
A ++ E G PG + +G +G+ T PQ S +G QGA G+
Sbjct: 1007 AQAGQQSLE---GDPGQDPE--PEGALLGSSDTGPQ--SGEG----VPQGAAPEGVSEAP 1055
Query: 562 AEAG 565
AEAG
Sbjct: 1056 AEAG 1059
Score = 42.4 bits (98), Expect = 0.003
Identities = 48/199 (24%), Positives = 71/199 (35%), Gaps = 37/199 (18%)
Query: 1163 GSAQP------SPPDDLDAGGLAQRLRGHGAEGPQEPK-------EAADRADGAAPGVAS 1209
G AQP +P + +A ++ + AEG +P+ EA + A GV +
Sbjct: 2123 GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEA 2182
Query: 1210 RNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPR 1269
A + G EAP AE A+ + G AP EP V P
Sbjct: 2183 PEAEGEAQPESEGIEAPE----AEGEAQPELEGVEAPEA------EEEAQPEPEGVETPE 2232
Query: 1270 AHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAAD 1329
A G + + + + S S+ D A+E +P P P PP +
Sbjct: 2233 AEGEAQPESEGE----TQGEKKGSPQVSLGD----GQSEEASESSSPVPEDRPTPPPS-- 2282
Query: 1330 SQQPPGGSSPSEEPPPSPG 1348
PGG +P + P G
Sbjct: 2283 ----PGGDTPHQRPGSQTG 2297
Score = 42.0 bits (97), Expect = 0.005
Identities = 52/212 (24%), Positives = 81/212 (38%), Gaps = 35/212 (16%)
Query: 1218 SKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSHV 1277
SK G A E+R P+ LV G P G V R +PG+ P A S
Sbjct: 785 SKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPS-- 842
Query: 1278 RDADLL---------KKRRSRLRNSSSFSMDDPDAGAMGAA-AAEGQAPDPSPAPGPPTA 1327
+A L + R R SSS G+ G++ + + P SP G
Sbjct: 843 PEASWLCGRYCPTPPRGRPCPQRRSSS-------CGSTGSSHQSTARGPGGSPQEG---- 891
Query: 1328 ADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQIDGRAAEVEMQ 1387
++QP P PSPG +G R SQ A + L +E+ G + + +
Sbjct: 892 --TRQP--------GPTPSPGPNSGASRRSSASQ--GAGSRGLSEEKTLRSGGGPQGQEE 939
Query: 1388 LRSLMESGANKLQEEVLIQEWFTLVNKKNALI 1419
+ S + E +++EW + ++ L+
Sbjct: 940 ASGVSPSSLPRSSPEAVVREWLDNIPEEPILM 971
Score = 39.7 bits (91), Expect = 0.022
Identities = 163/709 (22%), Positives = 252/709 (35%), Gaps = 131/709 (18%)
Query: 199 PGAPEARA--RVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPA 256
PG A+ R P P+ S C G+ PQ+ +S + + +
Sbjct: 829 PGTQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQS--------- 879
Query: 257 RTSRGQGSERANEAGGQVGPEAPRPPETSPEMRSSR-QPAQDTAPTPAPRLRKGSDALRP 315
T+RG G E Q GP P + RSS Q A + LR G
Sbjct: 880 -TARGPGGS-PQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGG---- 933
Query: 316 PVPQGEDEVPKASGAPPAGLGSA------RE----------TQAQACPQEGTEAHGARL- 358
PQG++E ASG P+ L + RE E T A G L
Sbjct: 934 --PQGQEE---ASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLR 988
Query: 359 GPSIED------KGSGDPF--GRQRLKAEEMDTEDRPEASGV-----DTEPRSG-GREAN 404
GP ++ +G G+P G+Q L E D PE G DT P+SG G
Sbjct: 989 GPEVDPGDDHSLEGLGEPAQAGQQSL---EGDPGQDPEPEGALLGSSDTGPQSGEGVPQG 1045
Query: 405 TKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMPE--ARCRGTPEAPPRGS 462
GV AE + A + A R +R + + +T +M +G P + P S
Sbjct: 1046 AAPEGVSEAPAE-AGADREAPAGCRVSLRALPGRVSASTQIMRALMGSKQGRPSSVPEVS 1104
Query: 463 QGRLGVRTRDEAPSGLSLPPAEPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGIEGTG 522
+ + R +G + L L+ G + E
Sbjct: 1105 RP---MARRLSCSAGALITC---------LASLQLFEEDLGSPASKVRFKDSPRYQELLS 1152
Query: 523 LEQGPSVGAISTRPQVSS------WQGALLSTAQGAISRGLGGWEAE-------AGGSGD 569
+ + G Q+ S W AL A++ + +GGSG+
Sbjct: 1153 ISKDLWPGCDVGEDQLDSGLWELTWSQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGE 1212
Query: 570 LETETEVVG-LEVLGTQEKEVEGSGFPETRTLEIEILGALE--KEAARSRVLESEVAGTA 626
+ G L GT+ + P++RT E G LE ++ L + A
Sbjct: 1213 SSVPCAMDGTLVTQGTELPLKTSNQRPDSRTYESP--GDLENQQQCCFPTFLNARACACA 1270
Query: 627 QCEGLETQETEVGVIET------PGTETEVLGTQKTEAG--GSGVLQTRTTIAETEVLVT 678
E +++E + T E + ++T+ G G G+ + + ET+ T
Sbjct: 1271 TNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETK---T 1327
Query: 679 QEISGDLGPLKIEDTIQSEMLGTQETEVEASRVPESEAEGTEAKILGTQEITARDSGVRE 738
+E + G +++E+T ++E G QE E + + E+ EG + + GV+
Sbjct: 1328 EEGLQEEG-VQLEETKETEGEGQQEEEAQLEEIEETGGEGLQ------------EEGVQL 1374
Query: 739 IEAEIAESDILVAQEIEVGLLGVLGIETGAAEGAILGTQEIASRDSGVPGLEADTTGIQV 798
E + L + +E GL E G E + QE++ S + +Q
Sbjct: 1375 EEVKEGPEGGLQGEALEEGLK-----EEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQE 1429
Query: 799 KEVG---GSEVPEIATGTAE-----TEILGTQEIAS-RSSG---VPGLE 835
+E G S P A GT E + + T AS R SG PGLE
Sbjct: 1430 EEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLE 1478
Score = 35.4 bits (80), Expect = 0.42
Identities = 48/211 (22%), Positives = 74/211 (35%), Gaps = 29/211 (13%)
Query: 1163 GSAQPSPP--DDLDAGGLAQRLRGHGA---EGPQEPK-------EAADRADGAAPGVASR 1210
G AQP + +A G AQ+ G A EG +P+ EA A + GV ++
Sbjct: 2092 GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQ 2151
Query: 1211 NAVAGRASKDGGAEAPRESRPAEVPAEGL----VNGAGAPGGGGVRLRRPSVNGEPG--S 1264
+A + G EA A+ EG+ G P G+ +P
Sbjct: 2152 DAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEG 2211
Query: 1265 VPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGP 1324
V P A + + + S G+ + +GQ+ +
Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEE------- 2264
Query: 1325 PTAADSQQPPGGSSPSEEPPPSPGEEAGLQR 1355
A++S P P+ PPPSPG + QR
Sbjct: 2265 --ASESSSPVPEDRPT--PPPSPGGDTPHQR 2291
Score = 34.7 bits (78), Expect = 0.72
Identities = 201/976 (20%), Positives = 321/976 (32%), Gaps = 166/976 (17%)
Query: 161 GRATDDDMQSLASLMSVKPSDVGNLDDFAESD-EDEAHGPGAPEARARVPQPDPSRELKT 219
G+A + Q AS S +L D + E G G +A +P L
Sbjct: 557 GKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPL-VLGL 615
Query: 220 LCEEEEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPARTSRGQGSERANEA--------- 270
C + EG S + + SA + P+ G+ + R +
Sbjct: 616 SCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTH 675
Query: 271 ---GGQVGPEAPRPPETSPEMRSSRQPAQDTAPTPAPRLRKGSDALRPPVPQGEDEVPKA 327
V + PRPPE + P + + G+ LRPP +
Sbjct: 676 SPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGN--LRPP----------S 723
Query: 328 SGAPPAG--LGSARETQAQACPQE---GTEAHGARLGPSIEDKGSG-------------- 368
SG+ P+ LG++ T A + G H A D GS
Sbjct: 724 SGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDS 783
Query: 369 -DPFGRQRLKAEEMDTED----------RPEASGVDTEPRSGGREANTKRSG-VRAGEAE 416
G L E DT RPE V + T+ + + G +
Sbjct: 784 CSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSP 843
Query: 417 ESSAVCQVDAEQRSKVRHVDTKGPEA---TGVMPEARCRGTPEAPPRGSQGRLGVRTRDE 473
E+S +C + R + + TG ++ RG +P G TR
Sbjct: 844 EASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEG--------TRQP 895
Query: 474 APSGLSLPPAEPAGHSGQLGDLEGARAAAGQEREGAEVRGGAPGIEGTGLEQGPSVGAIS 533
P+ P +G S + +GA + E + GG G E S+ S
Sbjct: 896 GPTP---SPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGVSPSSLPRSS 952
Query: 534 TRPQVSSW-----QGALLSTAQ------GAISRGLGGWEAEAGGSGDLETETEVV----- 577
V W + +L T + GA GL G E + G LE E
Sbjct: 953 PEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQ 1012
Query: 578 GLEVLGTQEKEVEGS--GFPETRTLEIEILGALEKEAARSRVLESEVAGTAQCEGLETQE 635
LE Q+ E EG+ G +T E + + AA V E+ A E
Sbjct: 1013 SLEGDPGQDPEPEGALLGSSDTGPQSGE---GVPQGAAPEGVSEAPAEAGADREA--PAG 1067
Query: 636 TEVGVIETPGTETEVLGTQKTEAGGSGVLQTRTTIAETEVLVTQEISGDLGPL---KIED 692
V + PG + TQ A +++ E + + +S G L
Sbjct: 1068 CRVSLRALPGRVSA--STQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGALITCLASL 1125
Query: 693 TIQSEMLGTQETEVEASRVPESEAEGTEAKIL------GTQEITARDSGVREIEAEIAES 746
+ E LG+ ++V P + + +K L G ++ DSG+ E+ A
Sbjct: 1126 QLFEEDLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQL---DSGLWELTWSQALP 1182
Query: 747 DILVAQEIEVGLLGVLGIETGAAEGAILGTQEIASRDSGVPGLEADTTGIQVKEVG---G 803
D+ E ++ G + + S +S VP T Q E+
Sbjct: 1183 DLGSHAMTE-------NFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTS 1235
Query: 804 SEVPEIATGTAETEILGTQE------IASRSSGVPGLESEVAGAQETEVGGSGISGPEAG 857
++ P+ T + ++ Q+ + +R+ E E E + S +
Sbjct: 1236 NQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAEN 1295
Query: 858 MAEARVLMTRKTEIIVPEAEKEEAQTSGVQEAETRVGSALKYEALRAPVTQPRVLGSQEA 917
+ V + E E +EEA VQ ET+ L+ E ++ T+
Sbjct: 1296 TVQEEVQLEETKEGTEGEGLQEEA----VQLEETKTEEGLQEEGVQLEETK--------- 1342
Query: 918 KAEISGVQGSETQVLRVQEAEAGVWGMSEGKSGAWGAQEAEMKVLESPENKSGTFKAQEA 977
+ E G Q E Q+ ++E +G G QE +++ +E
Sbjct: 1343 ETEGEGQQEEEAQLEEIEE------------TGGEGLQEEGVQL-------------EEV 1377
Query: 978 EAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPE--KAEEDRRLPGSQAPPA 1035
+ G G +G+ E L E LPE S G ASSP+ ++ED + +A A
Sbjct: 1378 KEGPEGGLQGEALEEGLKEEGLPEE--GSVHGQELSEASSPDGKGSQEDDPVQEEEAGRA 1435
Query: 1036 LVSSSQSLLEWCQEVT 1051
S+ E +E T
Sbjct: 1436 SASAEPCPAEGTEEPT 1451
Score = 34.7 bits (78), Expect = 0.72
Identities = 54/263 (20%), Positives = 86/263 (32%), Gaps = 23/263 (8%)
Query: 1152 EGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRN 1211
EG G G+ R+ + + + +AQ G A+ G++ R
Sbjct: 1742 EGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERG 1801
Query: 1212 AVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGS--VPPPR 1269
G+ S ++ E A G + + G G+ +P S V P
Sbjct: 1802 ETGGQGS------GHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPE 1855
Query: 1270 AHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAAD 1329
A G + + + P++ + AE + S P A
Sbjct: 1856 AEGDAQEAEGE--AQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEK 1913
Query: 1330 SQQPPGGS-----SPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQIDGRAAEV 1384
QP S + E+ P S G EA Q ++ +Q + Q E I+ + AE
Sbjct: 1914 EAQPETESVEALETEGEDEPESEGAEA--QEAEEAAQEAEGQTQ---PESEVIESQEAEE 1968
Query: 1385 EMQLRSLMESGANKLQEEVLIQE 1407
E Q S L+ EV QE
Sbjct: 1969 EAQPES---EDVEALEVEVETQE 1988
Score = 32.0 bits (71), Expect = 4.7
Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 12/110 (10%)
Query: 192 DEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAPVSA 251
+E HG EA + P S+E + +EEE G+ A A P AE T
Sbjct: 1401 EEGSVHGQELSEASS--PDGKGSQEDDPV-QEEEAGRA---SASAEPCPAEGTE----EP 1450
Query: 252 PAPPARTSRGQGSERANEAGGQVGPEAPRPPETS--PEMRSSRQPAQDTA 299
PP+ S S ++G Q+ P +PP + + + QP Q A
Sbjct: 1451 TEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAA 1500
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 87.0 bits (214), Expect = 1e-16
Identities = 42/100 (42%), Positives = 61/100 (61%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
S +LL+WCQ+ T GY + ITNF++SW +GLAFCA+LH + P I Y L+ K+N
Sbjct: 882 SKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRN 941
Query: 1098 NKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQI 1137
AF+ ++G+ LE ++M+ PD VM Y+ QI
Sbjct: 942 LLLAFEAAESVGIKPSLELSEMLYTDRPDWQSVMQYVAQI 981
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 87.0 bits (214), Expect = 1e-16
Identities = 42/100 (42%), Positives = 61/100 (61%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
S +LL+WCQ+ T GY + ITNF++SW +GLAFCA+LH + P I Y L+ K+N
Sbjct: 963 SKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRN 1022
Query: 1098 NKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQI 1137
AF+ ++G+ LE ++M+ PD VM Y+ QI
Sbjct: 1023 LLLAFEAAESVGIKPSLELSEMLYTDRPDWQSVMQYVAQI 1062
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 86.3 bits (212), Expect = 2e-16
Identities = 45/98 (45%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
S+ +LL WCQ T GY V I NFTTSWR+GLAF A++HR PD +D++ L N N
Sbjct: 181 SAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYN 240
Query: 1098 NKQAF-DGFAALGVSRLLEPADMVLLSVPDKLIVMTYL 1134
++AF LG++RLL+P D V + PD+ ++TY+
Sbjct: 241 LQRAFRTAEQHLGLARLLDPED-VNMEAPDEKSIITYV 277
Score = 35.8 bits (81), Expect = 0.32
Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 21/186 (11%)
Query: 1336 GSSPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESG 1395
G+ S P + GL++ Q A L+ + ++Q+ A +VE + E
Sbjct: 1579 GALASLRSPEAEAVRRGLEQLQSA----WAGLREAAERRQQVLDAAFQVEQYYFDVAEVE 1634
Query: 1396 ANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQ 1455
A ++E+L+ ++++ L + LQL ++ E LSR+ RA+L E
Sbjct: 1635 AWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALL--EMGH 1692
Query: 1456 KTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKLSRQLS 1515
S Q R Q S V++ +++L + R+ALE+ L +LSRQ+S
Sbjct: 1693 PDSEQISRRQ-------SQVDRLYVALKELGEERRVALEQQYWL--------YQLSRQVS 1737
Query: 1516 RRERCV 1521
E +
Sbjct: 1738 ELEHWI 1743
Score = 34.7 bits (78), Expect = 0.72
Identities = 53/218 (24%), Positives = 78/218 (35%), Gaps = 27/218 (12%)
Query: 224 EEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEAPRPPE 283
E G+ P A+P +A +T P +A R R + ++RA E + PE +
Sbjct: 2197 EIPGRVEPAALPAAPEDAAETPATPAAAEQVRPRPERQESADRAEELPRRRRPERQESVD 2256
Query: 284 TSPEMRSSRQP-AQDTAPTPA------------PRLRKGSDALRPPVPQGEDEVPKASGA 330
S E R+P Q++A A R R+ + E E+P G
Sbjct: 2257 QSEEAARRRRPERQESAEHEAAHSLTLGRYEQMERRRERRERRLERQESSEQEMP-IRGD 2315
Query: 331 PPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEAS 390
G + + Q QE G GPS+ P GR E + RP+
Sbjct: 2316 LVKGKATLADIVEQL--QEKEAGPGLPAGPSLPQPRELPP-GRLPNGLELPERTPRPDRP 2372
Query: 391 GV--------DTEPRSGGREANTKRSGVRAGEAEESSA 420
PR GG ++RS R+ A+ SA
Sbjct: 2373 RARDRPKPRRRPRPREGGEGGGSRRS--RSAPAQGGSA 2408
>gi|7662284 microtubule associated monoxygenase, calponin and LIM
domain containing 2 [Homo sapiens]
Length = 1124
Score = 85.1 bits (209), Expect = 5e-16
Identities = 44/108 (40%), Positives = 64/108 (59%), Gaps = 1/108 (0%)
Query: 1043 LLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQAF 1102
LL WCQ+ T GY+ V +T+ TTSWR+GLA CAI+HRF P+ I++ SL+ + +NN+ AF
Sbjct: 522 LLTWCQQQTEGYQHVNVTDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQLAF 581
Query: 1103 D-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLV 1149
D G+ + +M PDKL ++ YL + G L+ V
Sbjct: 582 DVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRGTPLRPV 629
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 84.7 bits (208), Expect = 6e-16
Identities = 49/164 (29%), Positives = 80/164 (48%)
Query: 974 AQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAP 1033
++E + + E A + P+ ++S A + EE + + A
Sbjct: 948 SEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAR 1007
Query: 1034 PALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLN 1093
S +LL+WCQ+ T GY+ + ITNF++SW +GLAFCA+LH + P I Y L+ +
Sbjct: 1008 EYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQD 1067
Query: 1094 IKQNNKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQI 1137
++N AF ++G+ L+ +MV PD VM Y+ I
Sbjct: 1068 KRRNFMLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAI 1111
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 84.7 bits (208), Expect = 6e-16
Identities = 49/164 (29%), Positives = 80/164 (48%)
Query: 974 AQEAEAGVLGNEKGKEAEGSLTEASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAP 1033
++E + + E A + P+ ++S A + EE + + A
Sbjct: 948 SEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAR 1007
Query: 1034 PALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLN 1093
S +LL+WCQ+ T GY+ + ITNF++SW +GLAFCA+LH + P I Y L+ +
Sbjct: 1008 EYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQD 1067
Query: 1094 IKQNNKQAFDGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQI 1137
++N AF ++G+ L+ +MV PD VM Y+ I
Sbjct: 1068 KRRNFMLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAI 1111
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 84.3 bits (207), Expect = 8e-16
Identities = 44/98 (44%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
S+ +LL WCQ T GY V + NFTTSWR+GLAF AI+H+ PD +D+ SL N N
Sbjct: 177 SAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYN 236
Query: 1098 NKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYL 1134
+ AF+ LG+++LL+P D V + PD+ ++TY+
Sbjct: 237 LQNAFNLAEKELGLTKLLDPED-VNVDQPDEKSIITYV 273
Score = 34.3 bits (77), Expect = 0.95
Identities = 39/176 (22%), Positives = 79/176 (44%), Gaps = 8/176 (4%)
Query: 1349 EEAGLQRFQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVL--IQ 1406
+E + + T + ++++AL E ++I G+ + M+ L+E L E+L I+
Sbjct: 265 DEKSIITYVATYYHYFSKMKALAVEGKRI-GKVLDHAMEAERLVEK-YESLASELLQWIE 322
Query: 1407 EWFTLVNKK---NALIRRQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQHR 1463
+ +N + N+L Q+QLQ + +E+ + + +L K A +
Sbjct: 323 QTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQK 382
Query: 1464 EQLLLE-ELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKLSRQLSRRE 1518
E L+S +N+ E + +H+ +AL + + LEQ + R+ + RE
Sbjct: 383 VYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRE 438
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 84.0 bits (206), Expect = 1e-15
Identities = 71/242 (29%), Positives = 109/242 (45%), Gaps = 41/242 (16%)
Query: 1310 AAEGQAPDPSPAPGPPTA--ADSQQPP---------------GGSSPSEEPPPSPG---- 1348
AA P P P P PPTA ADS+ P SS EE P
Sbjct: 455 AAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLK 514
Query: 1349 EEAGLQRFQDT------------------SQYVCAELQALEQEQRQIDGRAAEVEMQLRS 1390
E+ L+R + +Q + +L+ +E+ QR + + +E LR
Sbjct: 515 EKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRG 574
Query: 1391 LMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLA 1450
+SG E L+QEWF LV +KN L+R + +L ++ +E +LE L ++LR +
Sbjct: 575 EADSGTQ--DEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKML 632
Query: 1451 IEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKL 1510
E+ QK + EQ + EL+ ++ QRD+LV L+ + ED+ E + R +L
Sbjct: 633 KEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQL 692
Query: 1511 SR 1512
SR
Sbjct: 693 SR 694
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 83.2 bits (204), Expect = 2e-15
Identities = 46/115 (40%), Positives = 66/115 (57%), Gaps = 8/115 (6%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASL---DPLNI 1094
S+ + LL WCQ T YR V + NF TSW++GLA CA++HR PD IDYA L DP+
Sbjct: 159 SAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIG- 217
Query: 1095 KQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYL-CQIRAFCTGQELQ 1147
N AF+ L + ++L+ D+V PD+ +MTY+ C AF ++ +
Sbjct: 218 --NLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAE 270
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 82.0 bits (201), Expect = 4e-15
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 17/158 (10%)
Query: 996 EASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYR 1055
+ SL + V + A +P A K + ++ S+ ++LL W QE Y
Sbjct: 150 QPSLDDVSVVDSSPASSPPAKKCSKVQARWQM----------SARKALLLWAQEQCATYE 199
Query: 1056 GVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLL 1114
V +T+F +SWRNG+AF AI+H PD ID S+ + K N ++AF L + RLL
Sbjct: 200 SVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLL 259
Query: 1115 EPADMVLLSVPDKLIVMTYLCQIRAFC-----TGQELQ 1147
EP D+ ++ PD+ +MTY+ Q + TG+E Q
Sbjct: 260 EPEDVDVVD-PDEKSIMTYVAQFLQYSKDAPGTGEEAQ 296
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 82.0 bits (201), Expect = 4e-15
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 17/158 (10%)
Query: 996 EASLPEAQVASGAGAGAPRASSPEKAEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYR 1055
+ SL + V + A +P A K + ++ S+ ++LL W QE Y
Sbjct: 150 QPSLDDVSVVDSSPASSPPAKKCSKVQARWQM----------SARKALLLWAQEQCATYE 199
Query: 1056 GVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLL 1114
V +T+F +SWRNG+AF AI+H PD ID S+ + K N ++AF L + RLL
Sbjct: 200 SVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLL 259
Query: 1115 EPADMVLLSVPDKLIVMTYLCQIRAFC-----TGQELQ 1147
EP D+ ++ PD+ +MTY+ Q + TG+E Q
Sbjct: 260 EPEDVDVVD-PDEKSIMTYVAQFLQYSKDAPGTGEEAQ 296
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 82.0 bits (201), Expect = 4e-15
Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 6/121 (4%)
Query: 1032 APPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDP 1091
A AL+S+ ++LL WCQ T Y V IT+F+ SW +GL F A++H PD +DY SL P
Sbjct: 137 ASAALLSTKEALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHAHRPDLLDYGSLRP 196
Query: 1092 LNIKQNNKQAF-DGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCT----GQEL 1146
N AF LG+++LL+P D V + PD+ +MTY+ +C+ GQ +
Sbjct: 197 DRPLHNLAFAFLVAEQELGIAQLLDPED-VAAAQPDERSIMTYVSLYYHYCSRLHQGQTV 255
Query: 1147 Q 1147
Q
Sbjct: 256 Q 256
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 81.3 bits (199), Expect = 7e-15
Identities = 42/98 (42%), Positives = 61/98 (62%), Gaps = 2/98 (2%)
Query: 1038 SSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQN 1097
S+ +LL WCQ T GY V +TNFT+SW++GLAF A++H+ PD ID+ L N + N
Sbjct: 174 SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHN 233
Query: 1098 NKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYL 1134
+ AF+ LG+ LL+P D V PD+ ++TY+
Sbjct: 234 LEHAFNVAERQLGIIPLLDPED-VFTENPDEKSIITYV 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.128 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,197,698
Number of Sequences: 37866
Number of extensions: 3865861
Number of successful extensions: 40167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 273
Number of HSP's successfully gapped in prelim test: 1970
Number of HSP's that attempted gapping in prelim test: 24100
Number of HSP's gapped (non-prelim): 14987
length of query: 1523
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1408
effective length of database: 13,892,928
effective search space: 19561242624
effective search space used: 19561242624
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.